[{"Gene":"AANAT","Gene synonym":["SNAT"],"Ensembl":"ENSG00000129673","Gene description":"Aralkylamine N-acetyltransferase","Uniprot":["Q16613"],"Chromosome":"17","Position":"76453351-76470117","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Melatonin biosynthesis"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"11.0","testis":"4.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Bipolar cells":"302.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"2.5","Daudi":"2.0","SCLC-21H":"3.2","U-266\/70":"2.3","U-266\/84":"2.7","U-698":"3.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054321"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA054321":"AB_2682449"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"11.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"2.5","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"2.7","Cell RNA - U-698 [nTPM]":"3.6","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"302.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"7.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"19.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"AARS1","Gene synonym":["AARS","AlaRS","CMT2N"],"Ensembl":"ENSG00000090861","Gene description":"Alanyl-tRNA synthetase 1","Uniprot":["P49588"],"Chromosome":"16","Position":"70251983-70289707","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","RNA-binding","tRNA-binding"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Epilepsy","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cardiomyocytes":"25.1","Cytotrophoblasts":"63.0","Extravillous trophoblasts":"29.9","Hofbauer cells":"27.1","Syncytiotrophoblasts":"52.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034261","HPA040870","HPA044223"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"620000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034261":"AB_1562673","HPA040870":"AB_10794995","HPA044223":"AB_2678862"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Tissue RNA - adipose tissue [nTPM]":"43.7","Tissue RNA - adrenal gland [nTPM]":"54.7","Tissue RNA - amygdala [nTPM]":"60.1","Tissue RNA - appendix [nTPM]":"33.4","Tissue RNA - basal ganglia [nTPM]":"64.3","Tissue RNA - bone marrow [nTPM]":"7.9","Tissue RNA - breast [nTPM]":"41.4","Tissue RNA - cerebellum [nTPM]":"73.3","Tissue RNA - cerebral cortex [nTPM]":"88.6","Tissue RNA - cervix [nTPM]":"42.1","Tissue RNA - choroid plexus [nTPM]":"49.2","Tissue RNA - colon [nTPM]":"48.9","Tissue RNA - duodenum [nTPM]":"26.0","Tissue RNA - endometrium 1 [nTPM]":"49.8","Tissue RNA - epididymis [nTPM]":"49.6","Tissue RNA - esophagus [nTPM]":"29.5","Tissue RNA - fallopian tube [nTPM]":"40.4","Tissue RNA - gallbladder [nTPM]":"22.3","Tissue RNA - heart muscle [nTPM]":"47.9","Tissue RNA - hippocampal formation [nTPM]":"62.8","Tissue RNA - hypothalamus [nTPM]":"71.7","Tissue RNA - kidney [nTPM]":"43.6","Tissue RNA - liver [nTPM]":"72.0","Tissue RNA - lung [nTPM]":"45.3","Tissue RNA - lymph node [nTPM]":"30.0","Tissue RNA - medulla oblongata [nTPM]":"78.6","Tissue RNA - midbrain [nTPM]":"68.6","Tissue RNA - ovary [nTPM]":"37.3","Tissue RNA - pancreas [nTPM]":"75.8","Tissue RNA - parathyroid gland [nTPM]":"74.9","Tissue RNA - pituitary gland [nTPM]":"50.1","Tissue RNA - placenta [nTPM]":"35.6","Tissue RNA - pons [nTPM]":"84.9","Tissue RNA - prostate [nTPM]":"40.0","Tissue RNA - rectum [nTPM]":"26.2","Tissue RNA - retina [nTPM]":"59.3","Tissue RNA - salivary gland [nTPM]":"53.3","Tissue RNA - seminal vesicle [nTPM]":"47.2","Tissue RNA - skeletal muscle [nTPM]":"62.4","Tissue RNA - skin 1 [nTPM]":"28.8","Tissue RNA - small intestine [nTPM]":"32.7","Tissue RNA - smooth muscle [nTPM]":"47.8","Tissue RNA - spinal cord [nTPM]":"66.3","Tissue RNA - spleen [nTPM]":"38.3","Tissue RNA - stomach 1 [nTPM]":"51.8","Tissue RNA - testis [nTPM]":"23.8","Tissue RNA - thalamus [nTPM]":"74.8","Tissue RNA - thymus [nTPM]":"36.4","Tissue RNA - thyroid gland [nTPM]":"66.6","Tissue RNA - tongue [nTPM]":"39.7","Tissue RNA - tonsil [nTPM]":"35.5","Tissue RNA - urinary bladder [nTPM]":"45.9","Tissue RNA - vagina [nTPM]":"32.8","Tissue RNA - white matter [nTPM]":"83.9","Cell RNA - A-431 [nTPM]":"123.7","Cell RNA - A549 [nTPM]":"192.8","Cell RNA - AF22 [nTPM]":"52.9","Cell RNA - AN3-CA [nTPM]":"205.7","Cell RNA - ASC diff [nTPM]":"127.3","Cell RNA - ASC TERT1 [nTPM]":"115.0","Cell RNA - BEWO [nTPM]":"125.7","Cell RNA - BJ [nTPM]":"97.7","Cell RNA - BJ hTERT+ [nTPM]":"135.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"119.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"151.8","Cell RNA - CACO-2 [nTPM]":"162.5","Cell RNA - CAPAN-2 [nTPM]":"163.2","Cell RNA - Daudi [nTPM]":"140.4","Cell RNA - EFO-21 [nTPM]":"127.2","Cell RNA - fHDF\/TERT166 [nTPM]":"99.3","Cell RNA - GAMG [nTPM]":"90.8","Cell RNA - HaCaT [nTPM]":"137.2","Cell RNA - HAP1 [nTPM]":"160.5","Cell RNA - HBEC3-KT [nTPM]":"133.1","Cell RNA - HBF TERT88 [nTPM]":"170.7","Cell RNA - HDLM-2 [nTPM]":"63.2","Cell RNA - HEK 293 [nTPM]":"54.7","Cell RNA - HEL [nTPM]":"135.6","Cell RNA - HeLa [nTPM]":"78.0","Cell RNA - Hep G2 [nTPM]":"152.2","Cell RNA - HHSteC [nTPM]":"348.0","Cell RNA - HL-60 [nTPM]":"74.4","Cell RNA - HMC-1 [nTPM]":"77.2","Cell RNA - HSkMC [nTPM]":"133.9","Cell RNA - hTCEpi [nTPM]":"193.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"228.1","Cell RNA - hTERT-HME1 [nTPM]":"508.4","Cell RNA - hTERT-RPE1 [nTPM]":"91.4","Cell RNA - HUVEC TERT2 [nTPM]":"120.3","Cell RNA - JURKAT [nTPM]":"209.3","Cell RNA - K-562 [nTPM]":"176.0","Cell RNA - Karpas-707 [nTPM]":"173.4","Cell RNA - LHCN-M2 [nTPM]":"91.3","Cell RNA - MCF7 [nTPM]":"282.0","Cell RNA - MOLT-4 [nTPM]":"89.4","Cell RNA - NB-4 [nTPM]":"85.0","Cell RNA - NTERA-2 [nTPM]":"104.3","Cell RNA - OE19 [nTPM]":"160.0","Cell RNA - PC-3 [nTPM]":"108.5","Cell RNA - REH [nTPM]":"170.4","Cell RNA - RH-30 [nTPM]":"36.1","Cell RNA - RPMI-8226 [nTPM]":"317.0","Cell RNA - RPTEC TERT1 [nTPM]":"84.7","Cell RNA - RT4 [nTPM]":"60.3","Cell RNA - SCLC-21H [nTPM]":"67.9","Cell RNA - SH-SY5Y [nTPM]":"57.3","Cell RNA - SiHa [nTPM]":"269.5","Cell RNA - SK-BR-3 [nTPM]":"62.3","Cell RNA - SK-MEL-30 [nTPM]":"246.1","Cell RNA - SuSa [nTPM]":"75.8","Cell RNA - T-47d [nTPM]":"197.7","Cell RNA - THP-1 [nTPM]":"181.3","Cell RNA - TIME [nTPM]":"75.2","Cell RNA - U-138 MG [nTPM]":"85.2","Cell RNA - U-2 OS [nTPM]":"82.9","Cell RNA - U-2197 [nTPM]":"84.9","Cell RNA - U-251 MG [nTPM]":"78.8","Cell RNA - U-266\/70 [nTPM]":"233.8","Cell RNA - U-266\/84 [nTPM]":"174.2","Cell RNA - U-698 [nTPM]":"258.2","Cell RNA - U-87 MG [nTPM]":"155.4","Cell RNA - U-937 [nTPM]":"124.9","Cell RNA - WM-115 [nTPM]":"175.9","Blood RNA - basophil [nTPM]":"6.5","Blood RNA - classical monocyte [nTPM]":"7.8","Blood RNA - eosinophil [nTPM]":"2.7","Blood RNA - gdT-cell [nTPM]":"11.9","Blood RNA - intermediate monocyte [nTPM]":"13.2","Blood RNA - MAIT T-cell [nTPM]":"13.0","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"9.7","Blood RNA - memory CD8 T-cell [nTPM]":"11.7","Blood RNA - myeloid DC [nTPM]":"11.9","Blood RNA - naive B-cell [nTPM]":"9.1","Blood RNA - naive CD4 T-cell [nTPM]":"11.2","Blood RNA - naive CD8 T-cell [nTPM]":"12.2","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"22.7","Blood RNA - non-classical monocyte [nTPM]":"14.1","Blood RNA - plasmacytoid DC [nTPM]":"7.0","Blood RNA - T-reg [nTPM]":"8.0","Blood RNA - total PBMC [nTPM]":"12.6","Brain RNA - amygdala [nTPM]":"60.1","Brain RNA - basal ganglia [nTPM]":"64.3","Brain RNA - cerebellum [nTPM]":"73.3","Brain RNA - cerebral cortex [nTPM]":"88.6","Brain RNA - hippocampal formation [nTPM]":"62.8","Brain RNA - hypothalamus [nTPM]":"71.7","Brain RNA - medulla oblongata [nTPM]":"78.6","Brain RNA - midbrain [nTPM]":"68.6","Brain RNA - pons [nTPM]":"84.9","Brain RNA - spinal cord [nTPM]":"66.3","Brain RNA - thalamus [nTPM]":"74.8","Brain RNA - white matter [nTPM]":"83.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.9","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"AARS2","Gene synonym":["AARSL","bA444E17.1","KIAA1270"],"Ensembl":"ENSG00000124608","Gene description":"Alanyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q5JTZ9"],"Chromosome":"6","Position":"44298731-44313347","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","RNA-binding","tRNA-binding"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Disease variant","Neurodegeneration","Premature ovarian failure","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035636","HPA061396"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA035636":"AB_10670837","HPA061396":"AB_2684502"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"6.5","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"5.8","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"6.1","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"6.9","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"7.0","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"4.8","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"6.2","Tissue RNA - thyroid gland [nTPM]":"6.2","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"6.7","Cell RNA - A-431 [nTPM]":"14.6","Cell RNA - A549 [nTPM]":"9.9","Cell RNA - AF22 [nTPM]":"13.9","Cell RNA - AN3-CA [nTPM]":"23.8","Cell RNA - ASC diff [nTPM]":"8.1","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"18.3","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.6","Cell RNA - CACO-2 [nTPM]":"11.4","Cell RNA - CAPAN-2 [nTPM]":"7.1","Cell RNA - Daudi [nTPM]":"16.3","Cell RNA - EFO-21 [nTPM]":"16.2","Cell RNA - fHDF\/TERT166 [nTPM]":"4.8","Cell RNA - GAMG [nTPM]":"12.2","Cell RNA - HaCaT [nTPM]":"10.0","Cell RNA - HAP1 [nTPM]":"14.7","Cell RNA - HBEC3-KT [nTPM]":"16.0","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"23.7","Cell RNA - HEL [nTPM]":"18.9","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"14.5","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"17.9","Cell RNA - HMC-1 [nTPM]":"16.0","Cell RNA - HSkMC [nTPM]":"5.9","Cell RNA - hTCEpi [nTPM]":"9.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.0","Cell RNA - hTERT-HME1 [nTPM]":"10.2","Cell RNA - hTERT-RPE1 [nTPM]":"7.3","Cell RNA - HUVEC TERT2 [nTPM]":"9.5","Cell RNA - JURKAT [nTPM]":"21.8","Cell RNA - K-562 [nTPM]":"21.0","Cell RNA - Karpas-707 [nTPM]":"15.4","Cell RNA - LHCN-M2 [nTPM]":"6.2","Cell RNA - MCF7 [nTPM]":"16.0","Cell RNA - MOLT-4 [nTPM]":"14.2","Cell RNA - NB-4 [nTPM]":"15.9","Cell RNA - NTERA-2 [nTPM]":"9.9","Cell RNA - OE19 [nTPM]":"40.3","Cell RNA - PC-3 [nTPM]":"9.8","Cell RNA - REH [nTPM]":"16.4","Cell RNA - RH-30 [nTPM]":"8.7","Cell RNA - RPMI-8226 [nTPM]":"10.4","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"12.7","Cell RNA - SCLC-21H [nTPM]":"32.0","Cell RNA - SH-SY5Y [nTPM]":"11.4","Cell RNA - SiHa [nTPM]":"9.4","Cell RNA - SK-BR-3 [nTPM]":"10.9","Cell RNA - SK-MEL-30 [nTPM]":"15.5","Cell RNA - SuSa [nTPM]":"9.7","Cell RNA - T-47d [nTPM]":"9.9","Cell RNA - THP-1 [nTPM]":"21.6","Cell RNA - TIME [nTPM]":"8.4","Cell RNA - U-138 MG [nTPM]":"12.1","Cell RNA - U-2 OS [nTPM]":"13.5","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"13.9","Cell RNA - U-266\/70 [nTPM]":"8.8","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"16.5","Cell RNA - U-87 MG [nTPM]":"6.8","Cell RNA - U-937 [nTPM]":"15.9","Cell RNA - WM-115 [nTPM]":"22.1","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"6.5","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"6.7","Single Cell Type RNA - Adipocytes [nTPM]":"2.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.3","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"3.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.3","Single Cell Type RNA - Early spermatids [nTPM]":"10.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"6.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - T-cells [nTPM]":"4.1","Single Cell Type RNA - Theca cells [nTPM]":"4.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"ABCA4","Gene synonym":["ABCR","ARMD2","CORD3","FFM","RP19","STGD","STGD1"],"Ensembl":"ENSG00000198691","Gene description":"ATP binding cassette subfamily A member 4","Uniprot":["P78363"],"Chromosome":"1","Position":"93992834-94121148","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Transport","Vision"],"Molecular function":["Translocase"],"Disease involvement":["Age-related macular degeneration","Cone-rod dystrophy","Disease variant","Retinitis pigmentosa","Stargardt disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"choroid plexus":"144.6","retina":"461.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"450.4","Rod photoreceptor cells":"482.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"3.1"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"hippocampal formation":"9.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"3.1","EFO-21":"6.8","HeLa":"2.3","SK-BR-3":"3.0","SuSa":"3.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064420","HPA078826"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA064420":null,"HPA078826":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.45e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.72e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"144.6","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"2.5","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"8.4","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"9.3","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"8.7","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"461.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"2.9","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"1.4","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"3.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"9.3","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"1.4","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"27.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"450.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"21.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"37.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"482.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"ABCC1","Gene synonym":["GS-X","MRP","MRP1"],"Ensembl":"ENSG00000103222","Gene description":"ATP binding cassette subfamily C member 1","Uniprot":["P33527"],"Chromosome":"16","Position":"15949138-16143257","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Hydrolase","Translocase"],"Disease involvement":["Cancer-related genes","Deafness","FDA approved drug targets","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"49.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"79.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002380","HPA076011"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA002380":"AB_1844432","HPA076011":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.42e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.4","Tissue RNA - adrenal gland [nTPM]":"11.6","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"10.4","Tissue RNA - choroid plexus [nTPM]":"4.1","Tissue RNA - colon [nTPM]":"16.1","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"22.8","Tissue RNA - fallopian tube [nTPM]":"7.0","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"11.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"2.3","Tissue RNA - lung [nTPM]":"15.5","Tissue RNA - lymph node [nTPM]":"4.4","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"3.6","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"2.0","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"9.2","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"21.2","Tissue RNA - skin 1 [nTPM]":"9.7","Tissue RNA - small intestine [nTPM]":"12.4","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"15.7","Tissue RNA - stomach 1 [nTPM]":"15.0","Tissue RNA - testis [nTPM]":"13.1","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"4.3","Tissue RNA - thyroid gland [nTPM]":"21.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"15.4","Tissue RNA - vagina [nTPM]":"12.8","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"43.7","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"11.7","Cell RNA - ASC diff [nTPM]":"3.2","Cell RNA - ASC TERT1 [nTPM]":"4.5","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"15.4","Cell RNA - BJ hTERT+ [nTPM]":"19.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.8","Cell RNA - CACO-2 [nTPM]":"6.7","Cell RNA - CAPAN-2 [nTPM]":"34.8","Cell RNA - Daudi [nTPM]":"7.0","Cell RNA - EFO-21 [nTPM]":"79.6","Cell RNA - fHDF\/TERT166 [nTPM]":"29.6","Cell RNA - GAMG [nTPM]":"11.0","Cell RNA - HaCaT [nTPM]":"12.1","Cell RNA - HAP1 [nTPM]":"3.4","Cell RNA - HBEC3-KT [nTPM]":"12.4","Cell RNA - HBF TERT88 [nTPM]":"4.6","Cell RNA - HDLM-2 [nTPM]":"22.2","Cell RNA - HEK 293 [nTPM]":"4.4","Cell RNA - HEL [nTPM]":"16.4","Cell RNA - HeLa [nTPM]":"22.0","Cell RNA - Hep G2 [nTPM]":"16.3","Cell RNA - HHSteC [nTPM]":"25.1","Cell RNA - HL-60 [nTPM]":"5.9","Cell RNA - HMC-1 [nTPM]":"39.5","Cell RNA - HSkMC [nTPM]":"15.0","Cell RNA - hTCEpi [nTPM]":"9.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"2.3","Cell RNA - hTERT-RPE1 [nTPM]":"3.8","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"28.6","Cell RNA - K-562 [nTPM]":"17.8","Cell RNA - Karpas-707 [nTPM]":"6.8","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"5.4","Cell RNA - MOLT-4 [nTPM]":"12.0","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"3.5","Cell RNA - OE19 [nTPM]":"1.8","Cell RNA - PC-3 [nTPM]":"8.2","Cell RNA - REH [nTPM]":"41.9","Cell RNA - RH-30 [nTPM]":"7.8","Cell RNA - RPMI-8226 [nTPM]":"5.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"15.2","Cell RNA - SCLC-21H [nTPM]":"6.4","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"18.9","Cell RNA - SK-BR-3 [nTPM]":"17.8","Cell RNA - SK-MEL-30 [nTPM]":"3.6","Cell RNA - SuSa [nTPM]":"11.9","Cell RNA - T-47d [nTPM]":"6.2","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"3.5","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"11.4","Cell RNA - U-251 MG [nTPM]":"11.9","Cell RNA - U-266\/70 [nTPM]":"13.5","Cell RNA - U-266\/84 [nTPM]":"7.4","Cell RNA - U-698 [nTPM]":"3.3","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"8.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.6","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"13.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"14.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"9.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.1","Single Cell Type RNA - Early spermatids [nTPM]":"11.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.9","Single Cell Type RNA - Endothelial cells [nTPM]":"8.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.6","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"12.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"22.1","Single Cell Type RNA - Granulosa cells [nTPM]":"16.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.4","Single Cell Type RNA - Langerhans cells [nTPM]":"9.1","Single Cell Type RNA - Late spermatids [nTPM]":"14.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"12.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.2","Single Cell Type RNA - Paneth cells [nTPM]":"4.5","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"15.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"4.9","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"17.4","Single Cell Type RNA - Theca cells [nTPM]":"37.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"11.6"},{"Gene":"ABHD12","Gene synonym":["ABHD12A","BEM46L2","C20orf22","dJ965G21.2","DKFZP434P106"],"Ensembl":"ENSG00000100997","Gene description":"Abhydrolase domain containing 12, lysophospholipase","Uniprot":["Q8N2K0"],"Chromosome":"20","Position":"25294742-25390835","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Cataract","Deafness","Disease variant","Neuropathy","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"315.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026866"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026866":"AB_1844446"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.81e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.30e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.18e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"29.5","Tissue RNA - adrenal gland [nTPM]":"33.0","Tissue RNA - amygdala [nTPM]":"55.7","Tissue RNA - appendix [nTPM]":"27.4","Tissue RNA - basal ganglia [nTPM]":"67.3","Tissue RNA - bone marrow [nTPM]":"26.5","Tissue RNA - breast [nTPM]":"26.9","Tissue RNA - cerebellum [nTPM]":"70.0","Tissue RNA - cerebral cortex [nTPM]":"64.7","Tissue RNA - cervix [nTPM]":"32.1","Tissue RNA - choroid plexus [nTPM]":"35.9","Tissue RNA - colon [nTPM]":"37.0","Tissue RNA - duodenum [nTPM]":"47.0","Tissue RNA - endometrium 1 [nTPM]":"25.3","Tissue RNA - epididymis [nTPM]":"133.1","Tissue RNA - esophagus [nTPM]":"50.0","Tissue RNA - fallopian tube [nTPM]":"24.8","Tissue RNA - gallbladder [nTPM]":"33.4","Tissue RNA - heart muscle [nTPM]":"30.5","Tissue RNA - hippocampal formation [nTPM]":"77.3","Tissue RNA - hypothalamus [nTPM]":"58.2","Tissue RNA - kidney [nTPM]":"45.5","Tissue RNA - liver [nTPM]":"29.8","Tissue RNA - lung [nTPM]":"32.6","Tissue RNA - lymph node [nTPM]":"30.8","Tissue RNA - medulla oblongata [nTPM]":"70.9","Tissue RNA - midbrain [nTPM]":"64.6","Tissue RNA - ovary [nTPM]":"30.6","Tissue RNA - pancreas [nTPM]":"117.8","Tissue RNA - parathyroid gland [nTPM]":"55.3","Tissue RNA - pituitary gland [nTPM]":"42.1","Tissue RNA - placenta [nTPM]":"29.6","Tissue RNA - pons [nTPM]":"73.3","Tissue RNA - prostate [nTPM]":"35.5","Tissue RNA - rectum [nTPM]":"36.4","Tissue RNA - retina [nTPM]":"30.8","Tissue RNA - salivary gland [nTPM]":"36.9","Tissue RNA - seminal vesicle [nTPM]":"39.9","Tissue RNA - skeletal muscle [nTPM]":"13.3","Tissue RNA - skin 1 [nTPM]":"52.4","Tissue RNA - small intestine [nTPM]":"52.8","Tissue RNA - smooth muscle [nTPM]":"23.6","Tissue RNA - spinal cord [nTPM]":"66.0","Tissue RNA - spleen [nTPM]":"22.0","Tissue RNA - stomach 1 [nTPM]":"55.0","Tissue RNA - testis [nTPM]":"19.2","Tissue RNA - thalamus [nTPM]":"71.8","Tissue RNA - thymus [nTPM]":"23.4","Tissue RNA - thyroid gland [nTPM]":"80.8","Tissue RNA - tongue [nTPM]":"14.8","Tissue RNA - tonsil [nTPM]":"41.5","Tissue RNA - urinary bladder [nTPM]":"37.2","Tissue RNA - vagina [nTPM]":"35.1","Tissue RNA - white matter [nTPM]":"96.9","Cell RNA - A-431 [nTPM]":"67.2","Cell RNA - A549 [nTPM]":"148.3","Cell RNA - AF22 [nTPM]":"41.6","Cell RNA - AN3-CA [nTPM]":"50.9","Cell RNA - ASC diff [nTPM]":"79.6","Cell RNA - ASC TERT1 [nTPM]":"47.1","Cell RNA - BEWO [nTPM]":"93.3","Cell RNA - BJ [nTPM]":"97.0","Cell RNA - BJ hTERT+ [nTPM]":"84.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"73.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"84.6","Cell RNA - CACO-2 [nTPM]":"90.1","Cell RNA - CAPAN-2 [nTPM]":"93.0","Cell RNA - Daudi [nTPM]":"21.8","Cell RNA - EFO-21 [nTPM]":"53.3","Cell RNA - fHDF\/TERT166 [nTPM]":"77.0","Cell RNA - GAMG [nTPM]":"155.1","Cell RNA - HaCaT [nTPM]":"116.5","Cell RNA - HAP1 [nTPM]":"44.4","Cell RNA - HBEC3-KT [nTPM]":"56.8","Cell RNA - HBF TERT88 [nTPM]":"62.8","Cell RNA - HDLM-2 [nTPM]":"22.7","Cell RNA - HEK 293 [nTPM]":"41.9","Cell RNA - HEL [nTPM]":"33.3","Cell RNA - HeLa [nTPM]":"46.8","Cell RNA - Hep G2 [nTPM]":"128.4","Cell RNA - HHSteC [nTPM]":"59.3","Cell RNA - HL-60 [nTPM]":"33.3","Cell RNA - HMC-1 [nTPM]":"71.6","Cell RNA - HSkMC [nTPM]":"58.7","Cell RNA - hTCEpi [nTPM]":"42.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"85.4","Cell RNA - hTERT-HME1 [nTPM]":"44.1","Cell RNA - hTERT-RPE1 [nTPM]":"95.7","Cell RNA - HUVEC TERT2 [nTPM]":"33.2","Cell RNA - JURKAT [nTPM]":"37.8","Cell RNA - K-562 [nTPM]":"25.8","Cell RNA - Karpas-707 [nTPM]":"315.3","Cell RNA - LHCN-M2 [nTPM]":"72.8","Cell RNA - MCF7 [nTPM]":"142.5","Cell RNA - MOLT-4 [nTPM]":"51.8","Cell RNA - NB-4 [nTPM]":"31.0","Cell RNA - NTERA-2 [nTPM]":"29.4","Cell RNA - OE19 [nTPM]":"77.8","Cell RNA - PC-3 [nTPM]":"96.8","Cell RNA - REH [nTPM]":"39.2","Cell RNA - RH-30 [nTPM]":"95.3","Cell RNA - RPMI-8226 [nTPM]":"195.0","Cell RNA - RPTEC TERT1 [nTPM]":"43.4","Cell RNA - RT4 [nTPM]":"145.7","Cell RNA - SCLC-21H [nTPM]":"46.6","Cell RNA - SH-SY5Y [nTPM]":"39.7","Cell RNA - SiHa [nTPM]":"75.4","Cell RNA - SK-BR-3 [nTPM]":"198.9","Cell RNA - SK-MEL-30 [nTPM]":"133.8","Cell RNA - SuSa [nTPM]":"72.3","Cell RNA - T-47d [nTPM]":"67.4","Cell RNA - THP-1 [nTPM]":"47.6","Cell RNA - TIME [nTPM]":"44.6","Cell RNA - U-138 MG [nTPM]":"98.3","Cell RNA - U-2 OS [nTPM]":"63.0","Cell RNA - U-2197 [nTPM]":"57.1","Cell RNA - U-251 MG [nTPM]":"54.0","Cell RNA - U-266\/70 [nTPM]":"38.8","Cell RNA - U-266\/84 [nTPM]":"36.1","Cell RNA - U-698 [nTPM]":"33.4","Cell RNA - U-87 MG [nTPM]":"61.8","Cell RNA - U-937 [nTPM]":"38.7","Cell RNA - WM-115 [nTPM]":"57.3","Blood RNA - basophil [nTPM]":"15.8","Blood RNA - classical monocyte [nTPM]":"18.8","Blood RNA - eosinophil [nTPM]":"17.3","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"17.0","Blood RNA - MAIT T-cell [nTPM]":"7.5","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"10.2","Blood RNA - memory CD8 T-cell [nTPM]":"13.7","Blood RNA - myeloid DC [nTPM]":"17.9","Blood RNA - naive B-cell [nTPM]":"5.1","Blood RNA - naive CD4 T-cell [nTPM]":"8.9","Blood RNA - naive CD8 T-cell [nTPM]":"8.9","Blood RNA - neutrophil [nTPM]":"3.6","Blood RNA - NK-cell [nTPM]":"15.4","Blood RNA - non-classical monocyte [nTPM]":"17.7","Blood RNA - plasmacytoid DC [nTPM]":"17.0","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"8.6","Brain RNA - amygdala [nTPM]":"55.7","Brain RNA - basal ganglia [nTPM]":"67.3","Brain RNA - cerebellum [nTPM]":"70.0","Brain RNA - cerebral cortex [nTPM]":"64.7","Brain RNA - hippocampal formation [nTPM]":"77.3","Brain RNA - hypothalamus [nTPM]":"58.2","Brain RNA - medulla oblongata [nTPM]":"70.9","Brain RNA - midbrain [nTPM]":"64.6","Brain RNA - pons [nTPM]":"73.3","Brain RNA - spinal cord [nTPM]":"66.0","Brain RNA - thalamus [nTPM]":"71.8","Brain RNA - white matter [nTPM]":"96.9","Single Cell Type RNA - Adipocytes [nTPM]":"20.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.5","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"34.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"13.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"91.6","Single Cell Type RNA - dendritic cells [nTPM]":"22.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"97.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"33.7","Single Cell Type RNA - Early spermatids [nTPM]":"53.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.1","Single Cell Type RNA - Endothelial cells [nTPM]":"17.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.0","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"95.2","Single Cell Type RNA - Fibroblasts [nTPM]":"22.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.3","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"26.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"19.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"114.1","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"37.8","Single Cell Type RNA - Langerhans cells [nTPM]":"43.8","Single Cell Type RNA - Late spermatids [nTPM]":"107.1","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"62.4","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"58.7","Single Cell Type RNA - Muller glia cells [nTPM]":"44.1","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"67.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.9","Single Cell Type RNA - Paneth cells [nTPM]":"77.7","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"39.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"126.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.5","Single Cell Type RNA - Spermatocytes [nTPM]":"19.9","Single Cell Type RNA - Spermatogonia [nTPM]":"37.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"130.8","Single Cell Type RNA - T-cells [nTPM]":"18.0","Single Cell Type RNA - Theca cells [nTPM]":"19.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.3","Single Cell Type RNA - Urothelial cells [nTPM]":"35.2"},{"Gene":"AC022414.1","Gene synonym":[],"Ensembl":"ENSG00000284762","Gene description":"Phosphodiesterase 8B","Uniprot":[],"Chromosome":"5","Position":"77086732-77427124","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"12.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"2.4","HeLa":"5.3","SCLC-21H":"2.5"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036912"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036912":"AB_10670377"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"3.6","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"3.0","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":null,"Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"12.5","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":null,"Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"2.4","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"1.7","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"5.3","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"1.9","Cell RNA - SK-BR-3 [nTPM]":"1.5","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"3.0","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ACE","Gene synonym":["ACE1","CD143","DCP1"],"Ensembl":"ENSG00000159640","Gene description":"Angiotensin I converting enzyme","Uniprot":["P12821"],"Chromosome":"17","Position":"63477061-63498380","Protein class":["Candidate cardiovascular disease genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"265.1","testis":"101.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Early spermatids":"543.6","Late spermatids":"1322.9","Proximal enterocytes":"1172.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"8.1"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"ASC TERT1":"63.3","HUVEC TERT2":"33.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002426","CAB002921","HPA029298","HPA069790"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":104000000,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002426":"AB_442052","CAB002921":null,"HPA029298":"AB_10960255","HPA069790":"AB_2686197"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.4","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"4.8","Tissue RNA - basal ganglia [nTPM]":"8.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"2.5","Tissue RNA - cervix [nTPM]":"18.1","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"11.2","Tissue RNA - duodenum [nTPM]":"176.4","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"4.1","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"10.4","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"10.8","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"49.0","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"6.2","Tissue RNA - parathyroid gland [nTPM]":"18.7","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"23.8","Tissue RNA - skeletal muscle [nTPM]":"16.1","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"265.1","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"8.3","Tissue RNA - testis [nTPM]":"101.9","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"19.2","Tissue RNA - tongue [nTPM]":"10.0","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.6","Cell RNA - ASC TERT1 [nTPM]":"63.3","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"2.4","Cell RNA - BJ hTERT+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"5.1","Cell RNA - Daudi [nTPM]":"1.3","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"11.4","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"3.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"4.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.2","Cell RNA - HUVEC TERT2 [nTPM]":"33.8","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"5.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"11.7","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"8.2","Cell RNA - SH-SY5Y [nTPM]":"5.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"8.1","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"2.5","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"50.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.9","Single Cell Type RNA - Early spermatids [nTPM]":"543.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.0","Single Cell Type RNA - Endothelial cells [nTPM]":"34.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.3","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"33.7","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"1322.9","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"13.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"40.9","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1172.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"13.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"ACO2","Gene synonym":["ACONM"],"Ensembl":"ENSG00000100412","Gene description":"Aconitase 2","Uniprot":["Q99798"],"Chromosome":"22","Position":"41447830-41529273","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"567.7","skeletal muscle":"660.4","tongue":"695.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"374.2","Proximal tubular cells":"285.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001097"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA001097":"AB_1078092"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"88.8","Tissue RNA - adrenal gland [nTPM]":"81.6","Tissue RNA - amygdala [nTPM]":"154.2","Tissue RNA - appendix [nTPM]":"38.6","Tissue RNA - basal ganglia [nTPM]":"152.2","Tissue RNA - bone marrow [nTPM]":"32.0","Tissue RNA - breast [nTPM]":"52.4","Tissue RNA - cerebellum [nTPM]":"153.0","Tissue RNA - cerebral cortex [nTPM]":"190.0","Tissue RNA - cervix [nTPM]":"39.5","Tissue RNA - choroid plexus [nTPM]":"160.1","Tissue RNA - colon [nTPM]":"94.4","Tissue RNA - duodenum [nTPM]":"162.9","Tissue RNA - endometrium 1 [nTPM]":"42.0","Tissue RNA - epididymis [nTPM]":"26.1","Tissue RNA - esophagus [nTPM]":"60.4","Tissue RNA - fallopian tube [nTPM]":"53.6","Tissue RNA - gallbladder [nTPM]":"36.5","Tissue RNA - heart muscle [nTPM]":"567.7","Tissue RNA - hippocampal formation [nTPM]":"155.2","Tissue RNA - hypothalamus [nTPM]":"153.1","Tissue RNA - kidney [nTPM]":"138.9","Tissue RNA - liver [nTPM]":"73.9","Tissue RNA - lung [nTPM]":"40.7","Tissue RNA - lymph node [nTPM]":"40.5","Tissue RNA - medulla oblongata [nTPM]":"146.1","Tissue RNA - midbrain [nTPM]":"145.3","Tissue RNA - ovary [nTPM]":"30.8","Tissue RNA - pancreas [nTPM]":"53.8","Tissue RNA - parathyroid gland [nTPM]":"233.8","Tissue RNA - pituitary gland [nTPM]":"33.6","Tissue RNA - placenta [nTPM]":"30.5","Tissue RNA - pons [nTPM]":"147.8","Tissue RNA - prostate [nTPM]":"41.2","Tissue RNA - rectum [nTPM]":"69.6","Tissue RNA - retina [nTPM]":"46.9","Tissue RNA - salivary gland [nTPM]":"72.0","Tissue RNA - seminal vesicle [nTPM]":"49.5","Tissue RNA - skeletal muscle [nTPM]":"660.4","Tissue RNA - skin 1 [nTPM]":"45.5","Tissue RNA - small intestine [nTPM]":"158.5","Tissue RNA - smooth muscle [nTPM]":"43.7","Tissue RNA - spinal cord [nTPM]":"152.5","Tissue RNA - spleen [nTPM]":"44.7","Tissue RNA - stomach 1 [nTPM]":"110.2","Tissue RNA - testis [nTPM]":"35.1","Tissue RNA - thalamus [nTPM]":"186.3","Tissue RNA - thymus [nTPM]":"38.0","Tissue RNA - thyroid gland [nTPM]":"53.7","Tissue RNA - tongue [nTPM]":"695.8","Tissue RNA - tonsil [nTPM]":"43.3","Tissue RNA - urinary bladder [nTPM]":"52.5","Tissue RNA - vagina [nTPM]":"42.4","Tissue RNA - white matter [nTPM]":"159.6","Cell RNA - A-431 [nTPM]":"47.2","Cell RNA - A549 [nTPM]":"55.8","Cell RNA - AF22 [nTPM]":"56.5","Cell RNA - AN3-CA [nTPM]":"116.3","Cell RNA - ASC diff [nTPM]":"101.2","Cell RNA - ASC TERT1 [nTPM]":"69.8","Cell RNA - BEWO [nTPM]":"78.7","Cell RNA - BJ [nTPM]":"43.7","Cell RNA - BJ hTERT+ [nTPM]":"60.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"79.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"71.9","Cell RNA - CACO-2 [nTPM]":"81.2","Cell RNA - CAPAN-2 [nTPM]":"63.5","Cell RNA - Daudi [nTPM]":"115.7","Cell RNA - EFO-21 [nTPM]":"72.2","Cell RNA - fHDF\/TERT166 [nTPM]":"70.6","Cell RNA - GAMG [nTPM]":"60.3","Cell RNA - HaCaT [nTPM]":"109.8","Cell RNA - HAP1 [nTPM]":"108.8","Cell RNA - HBEC3-KT [nTPM]":"88.3","Cell RNA - HBF TERT88 [nTPM]":"42.8","Cell RNA - HDLM-2 [nTPM]":"75.8","Cell RNA - HEK 293 [nTPM]":"80.2","Cell RNA - HEL [nTPM]":"51.0","Cell RNA - HeLa [nTPM]":"73.7","Cell RNA - Hep G2 [nTPM]":"95.0","Cell RNA - HHSteC [nTPM]":"86.7","Cell RNA - HL-60 [nTPM]":"147.8","Cell RNA - HMC-1 [nTPM]":"77.8","Cell RNA - HSkMC [nTPM]":"120.8","Cell RNA - hTCEpi [nTPM]":"64.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"78.9","Cell RNA - hTERT-HME1 [nTPM]":"83.2","Cell RNA - hTERT-RPE1 [nTPM]":"61.7","Cell RNA - HUVEC TERT2 [nTPM]":"81.2","Cell RNA - JURKAT [nTPM]":"61.5","Cell RNA - K-562 [nTPM]":"72.9","Cell RNA - Karpas-707 [nTPM]":"118.4","Cell RNA - LHCN-M2 [nTPM]":"65.4","Cell RNA - MCF7 [nTPM]":"91.7","Cell RNA - MOLT-4 [nTPM]":"73.7","Cell RNA - NB-4 [nTPM]":"47.9","Cell RNA - NTERA-2 [nTPM]":"37.0","Cell RNA - OE19 [nTPM]":"282.6","Cell RNA - PC-3 [nTPM]":"115.1","Cell RNA - REH [nTPM]":"102.3","Cell RNA - RH-30 [nTPM]":"37.8","Cell RNA - RPMI-8226 [nTPM]":"162.1","Cell RNA - RPTEC TERT1 [nTPM]":"106.8","Cell RNA - RT4 [nTPM]":"97.3","Cell RNA - SCLC-21H [nTPM]":"37.8","Cell RNA - SH-SY5Y [nTPM]":"33.9","Cell RNA - SiHa [nTPM]":"112.2","Cell RNA - SK-BR-3 [nTPM]":"128.7","Cell RNA - SK-MEL-30 [nTPM]":"82.0","Cell RNA - SuSa [nTPM]":"44.9","Cell RNA - T-47d [nTPM]":"74.9","Cell RNA - THP-1 [nTPM]":"74.7","Cell RNA - TIME [nTPM]":"55.5","Cell RNA - U-138 MG [nTPM]":"60.0","Cell RNA - U-2 OS [nTPM]":"68.7","Cell RNA - U-2197 [nTPM]":"50.2","Cell RNA - U-251 MG [nTPM]":"45.0","Cell RNA - U-266\/70 [nTPM]":"64.7","Cell RNA - U-266\/84 [nTPM]":"92.1","Cell RNA - U-698 [nTPM]":"80.6","Cell RNA - U-87 MG [nTPM]":"102.0","Cell RNA - U-937 [nTPM]":"64.0","Cell RNA - WM-115 [nTPM]":"66.5","Blood RNA - basophil [nTPM]":"10.3","Blood RNA - classical monocyte [nTPM]":"52.9","Blood RNA - eosinophil [nTPM]":"18.1","Blood RNA - gdT-cell [nTPM]":"32.0","Blood RNA - intermediate monocyte [nTPM]":"76.4","Blood RNA - MAIT T-cell [nTPM]":"29.3","Blood RNA - memory B-cell [nTPM]":"49.4","Blood RNA - memory CD4 T-cell [nTPM]":"25.5","Blood RNA - memory CD8 T-cell [nTPM]":"34.9","Blood RNA - myeloid DC [nTPM]":"69.0","Blood RNA - naive B-cell [nTPM]":"46.4","Blood RNA - naive CD4 T-cell [nTPM]":"29.2","Blood RNA - naive CD8 T-cell [nTPM]":"30.8","Blood RNA - neutrophil [nTPM]":"9.0","Blood RNA - NK-cell [nTPM]":"39.4","Blood RNA - non-classical monocyte [nTPM]":"97.1","Blood RNA - plasmacytoid DC [nTPM]":"24.0","Blood RNA - T-reg [nTPM]":"41.2","Blood RNA - total PBMC [nTPM]":"58.6","Brain RNA - amygdala [nTPM]":"154.2","Brain RNA - basal ganglia [nTPM]":"152.2","Brain RNA - cerebellum [nTPM]":"153.0","Brain RNA - cerebral cortex [nTPM]":"190.0","Brain RNA - hippocampal formation [nTPM]":"155.2","Brain RNA - hypothalamus [nTPM]":"153.1","Brain RNA - medulla oblongata [nTPM]":"146.1","Brain RNA - midbrain [nTPM]":"145.3","Brain RNA - pons [nTPM]":"147.8","Brain RNA - spinal cord [nTPM]":"152.5","Brain RNA - thalamus [nTPM]":"186.3","Brain RNA - white matter [nTPM]":"159.6","Single Cell Type RNA - Adipocytes [nTPM]":"26.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.8","Single Cell Type RNA - Astrocytes [nTPM]":"45.4","Single Cell Type RNA - B-cells [nTPM]":"49.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"54.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"60.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"63.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"81.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"100.3","Single Cell Type RNA - dendritic cells [nTPM]":"33.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"190.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"131.0","Single Cell Type RNA - Ductal cells [nTPM]":"58.3","Single Cell Type RNA - Early spermatids [nTPM]":"14.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.7","Single Cell Type RNA - Endothelial cells [nTPM]":"26.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"53.2","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"60.0","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"77.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.1","Single Cell Type RNA - granulocytes [nTPM]":"40.6","Single Cell Type RNA - Granulosa cells [nTPM]":"56.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"64.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"91.5","Single Cell Type RNA - Horizontal cells [nTPM]":"53.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"99.1","Single Cell Type RNA - Ionocytes [nTPM]":"89.5","Single Cell Type RNA - Kupffer cells [nTPM]":"35.5","Single Cell Type RNA - Langerhans cells [nTPM]":"26.4","Single Cell Type RNA - Late spermatids [nTPM]":"8.9","Single Cell Type RNA - Leydig cells [nTPM]":"24.2","Single Cell Type RNA - Macrophages [nTPM]":"39.2","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"68.3","Single Cell Type RNA - Muller glia cells [nTPM]":"73.9","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"43.9","Single Cell Type RNA - Paneth cells [nTPM]":"103.5","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"63.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"374.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"285.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"59.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.5","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"38.4","Single Cell Type RNA - Spermatocytes [nTPM]":"26.4","Single Cell Type RNA - Spermatogonia [nTPM]":"38.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"193.2","Single Cell Type RNA - T-cells [nTPM]":"30.7","Single Cell Type RNA - Theca cells [nTPM]":"54.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"113.6","Single Cell Type RNA - Urothelial cells [nTPM]":"64.9"},{"Gene":"ACTG1","Gene synonym":["ACTG","DFNA20","DFNA26"],"Ensembl":"ENSG00000184009","Gene description":"Actin gamma 1","Uniprot":["P63261"],"Chromosome":"17","Position":"81509413-81523847","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Mental retardation","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"9107.1","Exocrine glandular cells":"8305.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041264","HPA041271"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4900000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041264":"AB_2677383","HPA041271":"AB_2677386"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.41e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-3"},"Tissue RNA - adipose tissue [nTPM]":"1548.5","Tissue RNA - adrenal gland [nTPM]":"950.4","Tissue RNA - amygdala [nTPM]":"523.3","Tissue RNA - appendix [nTPM]":"1325.4","Tissue RNA - basal ganglia [nTPM]":"549.3","Tissue RNA - bone marrow [nTPM]":"1130.2","Tissue RNA - breast [nTPM]":"1158.2","Tissue RNA - cerebellum [nTPM]":"582.8","Tissue RNA - cerebral cortex [nTPM]":"628.6","Tissue RNA - cervix [nTPM]":"1634.2","Tissue RNA - choroid plexus [nTPM]":"506.2","Tissue RNA - colon [nTPM]":"1258.5","Tissue RNA - duodenum [nTPM]":"994.5","Tissue RNA - endometrium 1 [nTPM]":"1629.9","Tissue RNA - epididymis [nTPM]":"558.1","Tissue RNA - esophagus [nTPM]":"2422.2","Tissue RNA - fallopian tube [nTPM]":"1315.8","Tissue RNA - gallbladder [nTPM]":"1179.5","Tissue RNA - heart muscle [nTPM]":"666.3","Tissue RNA - hippocampal formation [nTPM]":"548.5","Tissue RNA - hypothalamus [nTPM]":"677.3","Tissue RNA - kidney [nTPM]":"905.8","Tissue RNA - liver [nTPM]":"762.8","Tissue RNA - lung [nTPM]":"1516.1","Tissue RNA - lymph node [nTPM]":"1696.9","Tissue RNA - medulla oblongata [nTPM]":"652.8","Tissue RNA - midbrain [nTPM]":"592.5","Tissue RNA - ovary [nTPM]":"2046.6","Tissue RNA - pancreas [nTPM]":"1693.4","Tissue RNA - parathyroid gland [nTPM]":"608.2","Tissue RNA - pituitary gland [nTPM]":"824.5","Tissue RNA - placenta [nTPM]":"922.4","Tissue RNA - pons [nTPM]":"629.8","Tissue RNA - prostate [nTPM]":"723.8","Tissue RNA - rectum [nTPM]":"662.3","Tissue RNA - retina [nTPM]":"293.9","Tissue RNA - salivary gland [nTPM]":"1291.3","Tissue RNA - seminal vesicle [nTPM]":"643.0","Tissue RNA - skeletal muscle [nTPM]":"358.4","Tissue RNA - skin 1 [nTPM]":"1455.8","Tissue RNA - small intestine [nTPM]":"1026.3","Tissue RNA - smooth muscle [nTPM]":"739.2","Tissue RNA - spinal cord [nTPM]":"589.8","Tissue RNA - spleen [nTPM]":"1034.8","Tissue RNA - stomach 1 [nTPM]":"1385.5","Tissue RNA - testis [nTPM]":"438.5","Tissue RNA - thalamus [nTPM]":"611.8","Tissue RNA - thymus [nTPM]":"1347.8","Tissue RNA - thyroid gland [nTPM]":"1252.2","Tissue RNA - tongue [nTPM]":"270.9","Tissue RNA - tonsil [nTPM]":"1292.7","Tissue RNA - urinary bladder [nTPM]":"1540.3","Tissue RNA - vagina [nTPM]":"1571.3","Tissue RNA - white matter [nTPM]":"709.7","Cell RNA - A-431 [nTPM]":"3652.9","Cell RNA - A549 [nTPM]":"4010.4","Cell RNA - AF22 [nTPM]":"4601.5","Cell RNA - AN3-CA [nTPM]":"2275.7","Cell RNA - ASC diff [nTPM]":"813.0","Cell RNA - ASC TERT1 [nTPM]":"2758.2","Cell RNA - BEWO [nTPM]":"1601.3","Cell RNA - BJ [nTPM]":"4193.6","Cell RNA - BJ hTERT+ [nTPM]":"3154.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3546.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2675.5","Cell RNA - CACO-2 [nTPM]":"3699.5","Cell RNA - CAPAN-2 [nTPM]":"1690.3","Cell RNA - Daudi [nTPM]":"2114.0","Cell RNA - EFO-21 [nTPM]":"2566.1","Cell RNA - fHDF\/TERT166 [nTPM]":"4263.6","Cell RNA - GAMG [nTPM]":"2867.3","Cell RNA - HaCaT [nTPM]":"2049.5","Cell RNA - HAP1 [nTPM]":"1722.7","Cell RNA - HBEC3-KT [nTPM]":"3395.6","Cell RNA - HBF TERT88 [nTPM]":"1727.7","Cell RNA - HDLM-2 [nTPM]":"3745.8","Cell RNA - HEK 293 [nTPM]":"2549.8","Cell RNA - HEL [nTPM]":"1724.3","Cell RNA - HeLa [nTPM]":"1784.6","Cell RNA - Hep G2 [nTPM]":"3515.1","Cell RNA - HHSteC [nTPM]":"2165.8","Cell RNA - HL-60 [nTPM]":"1909.2","Cell RNA - HMC-1 [nTPM]":"2003.4","Cell RNA - HSkMC [nTPM]":"3599.7","Cell RNA - hTCEpi [nTPM]":"1366.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3586.4","Cell RNA - hTERT-HME1 [nTPM]":"938.0","Cell RNA - hTERT-RPE1 [nTPM]":"4516.4","Cell RNA - HUVEC TERT2 [nTPM]":"5237.2","Cell RNA - JURKAT [nTPM]":"1343.4","Cell RNA - K-562 [nTPM]":"331.2","Cell RNA - Karpas-707 [nTPM]":"2723.2","Cell RNA - LHCN-M2 [nTPM]":"3288.0","Cell RNA - MCF7 [nTPM]":"2677.4","Cell RNA - MOLT-4 [nTPM]":"6305.5","Cell RNA - NB-4 [nTPM]":"2235.8","Cell RNA - NTERA-2 [nTPM]":"1970.8","Cell RNA - OE19 [nTPM]":"2272.7","Cell RNA - PC-3 [nTPM]":"2122.3","Cell RNA - REH [nTPM]":"3520.6","Cell RNA - RH-30 [nTPM]":"1537.3","Cell RNA - RPMI-8226 [nTPM]":"1716.3","Cell RNA - RPTEC TERT1 [nTPM]":"3385.4","Cell RNA - RT4 [nTPM]":"2838.3","Cell RNA - SCLC-21H [nTPM]":"1234.4","Cell RNA - SH-SY5Y [nTPM]":"1284.1","Cell RNA - SiHa [nTPM]":"4804.4","Cell RNA - SK-BR-3 [nTPM]":"969.0","Cell RNA - SK-MEL-30 [nTPM]":"5127.0","Cell RNA - SuSa [nTPM]":"1530.7","Cell RNA - T-47d [nTPM]":"2192.3","Cell RNA - THP-1 [nTPM]":"1908.9","Cell RNA - TIME [nTPM]":"5402.3","Cell RNA - U-138 MG [nTPM]":"4755.5","Cell RNA - U-2 OS [nTPM]":"1993.3","Cell RNA - U-2197 [nTPM]":"2802.6","Cell RNA - U-251 MG [nTPM]":"7012.2","Cell RNA - U-266\/70 [nTPM]":"908.3","Cell RNA - U-266\/84 [nTPM]":"791.7","Cell RNA - U-698 [nTPM]":"1505.4","Cell RNA - U-87 MG [nTPM]":"3808.4","Cell RNA - U-937 [nTPM]":"1910.5","Cell RNA - WM-115 [nTPM]":"2940.1","Blood RNA - basophil [nTPM]":"4240.1","Blood RNA - classical monocyte [nTPM]":"1897.3","Blood RNA - eosinophil [nTPM]":"3013.3","Blood RNA - gdT-cell [nTPM]":"2108.9","Blood RNA - intermediate monocyte [nTPM]":"2333.9","Blood RNA - MAIT T-cell [nTPM]":"2026.4","Blood RNA - memory B-cell [nTPM]":"1297.8","Blood RNA - memory CD4 T-cell [nTPM]":"1892.2","Blood RNA - memory CD8 T-cell [nTPM]":"2024.3","Blood RNA - myeloid DC [nTPM]":"3012.5","Blood RNA - naive B-cell [nTPM]":"939.2","Blood RNA - naive CD4 T-cell [nTPM]":"1391.8","Blood RNA - naive CD8 T-cell [nTPM]":"1827.7","Blood RNA - neutrophil [nTPM]":"1532.7","Blood RNA - NK-cell [nTPM]":"1355.2","Blood RNA - non-classical monocyte [nTPM]":"2939.2","Blood RNA - plasmacytoid DC [nTPM]":"1616.5","Blood RNA - T-reg [nTPM]":"2980.5","Blood RNA - total PBMC [nTPM]":"5301.8","Brain RNA - amygdala [nTPM]":"523.3","Brain RNA - basal ganglia [nTPM]":"549.3","Brain RNA - cerebellum [nTPM]":"582.8","Brain RNA - cerebral cortex [nTPM]":"628.6","Brain RNA - hippocampal formation [nTPM]":"548.5","Brain RNA - hypothalamus [nTPM]":"677.3","Brain RNA - medulla oblongata [nTPM]":"652.8","Brain RNA - midbrain [nTPM]":"592.5","Brain RNA - pons [nTPM]":"629.8","Brain RNA - spinal cord [nTPM]":"589.8","Brain RNA - thalamus [nTPM]":"611.8","Brain RNA - white matter [nTPM]":"709.7","Single Cell Type RNA - Adipocytes [nTPM]":"1602.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"974.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"558.2","Single Cell Type RNA - Astrocytes [nTPM]":"107.1","Single Cell Type RNA - B-cells [nTPM]":"1285.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5276.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9107.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3827.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2541.1","Single Cell Type RNA - Bipolar cells [nTPM]":"493.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1477.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1943.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"233.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"825.0","Single Cell Type RNA - Club cells [nTPM]":"1924.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1140.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"244.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2002.6","Single Cell Type RNA - dendritic cells [nTPM]":"1886.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2460.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1058.5","Single Cell Type RNA - Ductal cells [nTPM]":"4368.6","Single Cell Type RNA - Early spermatids [nTPM]":"293.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1028.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1501.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1664.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1914.5","Single Cell Type RNA - Erythroid cells [nTPM]":"567.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8305.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4361.7","Single Cell Type RNA - Fibroblasts [nTPM]":"1595.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2440.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1433.3","Single Cell Type RNA - granulocytes [nTPM]":"588.7","Single Cell Type RNA - Granulosa cells [nTPM]":"3067.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1031.6","Single Cell Type RNA - Hepatocytes [nTPM]":"517.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"3219.5","Single Cell Type RNA - Horizontal cells [nTPM]":"267.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"65.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2206.9","Single Cell Type RNA - Ionocytes [nTPM]":"1957.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1426.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1807.7","Single Cell Type RNA - Late spermatids [nTPM]":"258.5","Single Cell Type RNA - Leydig cells [nTPM]":"1718.6","Single Cell Type RNA - Macrophages [nTPM]":"1840.3","Single Cell Type RNA - Melanocytes [nTPM]":"1398.1","Single Cell Type RNA - Microglial cells [nTPM]":"70.3","Single Cell Type RNA - monocytes [nTPM]":"4004.3","Single Cell Type RNA - Muller glia cells [nTPM]":"3402.9","Single Cell Type RNA - NK-cells [nTPM]":"1971.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"111.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7194.7","Single Cell Type RNA - Paneth cells [nTPM]":"2426.5","Single Cell Type RNA - Peritubular cells [nTPM]":"1363.9","Single Cell Type RNA - Plasma cells [nTPM]":"1369.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3987.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1673.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"566.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"950.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"571.1","Single Cell Type RNA - Sertoli cells [nTPM]":"1360.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"873.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2277.1","Single Cell Type RNA - Spermatocytes [nTPM]":"756.5","Single Cell Type RNA - Spermatogonia [nTPM]":"995.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3085.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5371.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2827.2","Single Cell Type RNA - T-cells [nTPM]":"1823.7","Single Cell Type RNA - Theca cells [nTPM]":"2394.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2187.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6279.2"},{"Gene":"ACTL6B","Gene synonym":["ACTL6","BAF53B"],"Ensembl":"ENSG00000077080","Gene description":"Actin like 6B","Uniprot":["O94805"],"Chromosome":"7","Position":"100643097-100656448","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"20.7","pituitary gland":"15.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"8.0","Excitatory neurons":"22.1","Horizontal cells":"6.7","Inhibitory neurons":"19.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"3.9","pancreatic cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"76","RNA cell line specific nTPM":{"SCLC-21H":"28.5","SH-SY5Y":"28.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045126"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli rim","Mitotic chromosome"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoli rim","Mitotic chromosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA045126":"AB_10961265"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"13.8","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"14.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"20.7","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"14.9","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"15.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"4.3","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"28.5","Cell RNA - SH-SY5Y [nTPM]":"28.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.8","Brain RNA - basal ganglia [nTPM]":"14.5","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"20.7","Brain RNA - hippocampal formation [nTPM]":"14.9","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"4.3","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ADAM22","Gene synonym":["MDC2"],"Ensembl":"ENSG00000008277","Gene description":"ADAM metallopeptidase domain 22","Uniprot":["Q9P0K1"],"Chromosome":"7","Position":"87934143-88202889","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"77.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"286.7","Inhibitory neurons":"304.9","Oligodendrocyte precursor cells":"184.0","Oligodendrocytes":"125.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.0"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"77.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"81.8","SH-SY5Y":"76.9","U-266\/84":"33.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050325","CAB079064"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB079064":null,"HPA050325":"AB_2681087"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"9.2","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"77.2","Tissue RNA - cerebral cortex [nTPM]":"30.6","Tissue RNA - cervix [nTPM]":"6.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.5","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"4.6","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"12.2","Tissue RNA - hypothalamus [nTPM]":"8.9","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"14.4","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"3.9","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"14.7","Tissue RNA - prostate [nTPM]":"11.0","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"10.3","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"5.1","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"13.8","Tissue RNA - thymus [nTPM]":"2.5","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"12.3","Cell RNA - A-431 [nTPM]":"2.5","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"5.8","Cell RNA - ASC diff [nTPM]":"1.4","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"3.5","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"8.3","Cell RNA - Daudi [nTPM]":"7.4","Cell RNA - EFO-21 [nTPM]":"2.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"7.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"20.5","Cell RNA - HEK 293 [nTPM]":"9.0","Cell RNA - HEL [nTPM]":"5.6","Cell RNA - HeLa [nTPM]":"5.4","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"6.9","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"6.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"8.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"81.8","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"6.7","Cell RNA - MOLT-4 [nTPM]":"8.9","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"11.6","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"2.6","Cell RNA - REH [nTPM]":"5.2","Cell RNA - RH-30 [nTPM]":"18.8","Cell RNA - RPMI-8226 [nTPM]":"10.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"4.1","Cell RNA - SCLC-21H [nTPM]":"25.9","Cell RNA - SH-SY5Y [nTPM]":"76.9","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"3.7","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"18.8","Cell RNA - U-266\/84 [nTPM]":"33.2","Cell RNA - U-698 [nTPM]":"5.9","Cell RNA - U-87 MG [nTPM]":"4.1","Cell RNA - U-937 [nTPM]":"14.2","Cell RNA - WM-115 [nTPM]":"7.2","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"9.2","Brain RNA - cerebellum [nTPM]":"77.2","Brain RNA - cerebral cortex [nTPM]":"30.6","Brain RNA - hippocampal formation [nTPM]":"12.2","Brain RNA - hypothalamus [nTPM]":"8.9","Brain RNA - medulla oblongata [nTPM]":"14.4","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"14.7","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"13.8","Brain RNA - white matter [nTPM]":"12.3","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"45.7","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"28.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"7.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.9","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"286.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"304.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"184.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"125.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"ADAM9","Gene synonym":["CORD9","KIAA0021","MCMP","MDC9","Mltng"],"Ensembl":"ENSG00000168615","Gene description":"ADAM metallopeptidase domain 9","Uniprot":["Q13443"],"Chromosome":"8","Position":"38996754-39105445","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes","Cone-rod dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Pancreatic endocrine cells":"179.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"4.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004000"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"740000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA004000":"AB_1844584"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.25e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.21e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"34.2","Tissue RNA - adrenal gland [nTPM]":"28.0","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"28.8","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"2.1","Tissue RNA - breast [nTPM]":"21.5","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"8.3","Tissue RNA - cervix [nTPM]":"34.8","Tissue RNA - choroid plexus [nTPM]":"11.4","Tissue RNA - colon [nTPM]":"32.9","Tissue RNA - duodenum [nTPM]":"24.5","Tissue RNA - endometrium 1 [nTPM]":"29.7","Tissue RNA - epididymis [nTPM]":"15.2","Tissue RNA - esophagus [nTPM]":"29.7","Tissue RNA - fallopian tube [nTPM]":"19.3","Tissue RNA - gallbladder [nTPM]":"47.1","Tissue RNA - heart muscle [nTPM]":"32.1","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"8.4","Tissue RNA - kidney [nTPM]":"34.9","Tissue RNA - liver [nTPM]":"13.5","Tissue RNA - lung [nTPM]":"51.4","Tissue RNA - lymph node [nTPM]":"9.7","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"7.5","Tissue RNA - ovary [nTPM]":"16.8","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"52.5","Tissue RNA - pituitary gland [nTPM]":"7.8","Tissue RNA - placenta [nTPM]":"47.4","Tissue RNA - pons [nTPM]":"9.0","Tissue RNA - prostate [nTPM]":"34.9","Tissue RNA - rectum [nTPM]":"41.7","Tissue RNA - retina [nTPM]":"18.5","Tissue RNA - salivary gland [nTPM]":"54.9","Tissue RNA - seminal vesicle [nTPM]":"34.8","Tissue RNA - skeletal muscle [nTPM]":"24.1","Tissue RNA - skin 1 [nTPM]":"16.1","Tissue RNA - small intestine [nTPM]":"23.0","Tissue RNA - smooth muscle [nTPM]":"51.6","Tissue RNA - spinal cord [nTPM]":"9.4","Tissue RNA - spleen [nTPM]":"24.0","Tissue RNA - stomach 1 [nTPM]":"44.2","Tissue RNA - testis [nTPM]":"11.1","Tissue RNA - thalamus [nTPM]":"10.6","Tissue RNA - thymus [nTPM]":"5.9","Tissue RNA - thyroid gland [nTPM]":"39.9","Tissue RNA - tongue [nTPM]":"25.0","Tissue RNA - tonsil [nTPM]":"13.2","Tissue RNA - urinary bladder [nTPM]":"56.1","Tissue RNA - vagina [nTPM]":"24.3","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"188.3","Cell RNA - A549 [nTPM]":"163.6","Cell RNA - AF22 [nTPM]":"63.5","Cell RNA - AN3-CA [nTPM]":"32.6","Cell RNA - ASC diff [nTPM]":"117.2","Cell RNA - ASC TERT1 [nTPM]":"374.0","Cell RNA - BEWO [nTPM]":"67.0","Cell RNA - BJ [nTPM]":"259.6","Cell RNA - BJ hTERT+ [nTPM]":"382.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"191.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"177.9","Cell RNA - CACO-2 [nTPM]":"82.7","Cell RNA - CAPAN-2 [nTPM]":"147.1","Cell RNA - Daudi [nTPM]":"10.1","Cell RNA - EFO-21 [nTPM]":"86.1","Cell RNA - fHDF\/TERT166 [nTPM]":"247.2","Cell RNA - GAMG [nTPM]":"156.7","Cell RNA - HaCaT [nTPM]":"79.5","Cell RNA - HAP1 [nTPM]":"30.8","Cell RNA - HBEC3-KT [nTPM]":"249.7","Cell RNA - HBF TERT88 [nTPM]":"373.2","Cell RNA - HDLM-2 [nTPM]":"6.9","Cell RNA - HEK 293 [nTPM]":"21.5","Cell RNA - HEL [nTPM]":"12.1","Cell RNA - HeLa [nTPM]":"102.8","Cell RNA - Hep G2 [nTPM]":"73.0","Cell RNA - HHSteC [nTPM]":"226.4","Cell RNA - HL-60 [nTPM]":"8.9","Cell RNA - HMC-1 [nTPM]":"19.1","Cell RNA - HSkMC [nTPM]":"287.5","Cell RNA - hTCEpi [nTPM]":"139.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"193.3","Cell RNA - hTERT-HME1 [nTPM]":"212.7","Cell RNA - hTERT-RPE1 [nTPM]":"341.0","Cell RNA - HUVEC TERT2 [nTPM]":"268.9","Cell RNA - JURKAT [nTPM]":"15.2","Cell RNA - K-562 [nTPM]":"21.5","Cell RNA - Karpas-707 [nTPM]":"53.2","Cell RNA - LHCN-M2 [nTPM]":"406.2","Cell RNA - MCF7 [nTPM]":"25.0","Cell RNA - MOLT-4 [nTPM]":"7.2","Cell RNA - NB-4 [nTPM]":"4.4","Cell RNA - NTERA-2 [nTPM]":"8.3","Cell RNA - OE19 [nTPM]":"175.2","Cell RNA - PC-3 [nTPM]":"46.7","Cell RNA - REH [nTPM]":"3.8","Cell RNA - RH-30 [nTPM]":"106.3","Cell RNA - RPMI-8226 [nTPM]":"27.6","Cell RNA - RPTEC TERT1 [nTPM]":"299.3","Cell RNA - RT4 [nTPM]":"62.4","Cell RNA - SCLC-21H [nTPM]":"6.4","Cell RNA - SH-SY5Y [nTPM]":"11.5","Cell RNA - SiHa [nTPM]":"78.4","Cell RNA - SK-BR-3 [nTPM]":"90.9","Cell RNA - SK-MEL-30 [nTPM]":"57.8","Cell RNA - SuSa [nTPM]":"72.9","Cell RNA - T-47d [nTPM]":"67.3","Cell RNA - THP-1 [nTPM]":"12.0","Cell RNA - TIME [nTPM]":"374.2","Cell RNA - U-138 MG [nTPM]":"109.9","Cell RNA - U-2 OS [nTPM]":"97.9","Cell RNA - U-2197 [nTPM]":"213.9","Cell RNA - U-251 MG [nTPM]":"124.1","Cell RNA - U-266\/70 [nTPM]":"12.9","Cell RNA - U-266\/84 [nTPM]":"29.5","Cell RNA - U-698 [nTPM]":"7.7","Cell RNA - U-87 MG [nTPM]":"175.8","Cell RNA - U-937 [nTPM]":"12.0","Cell RNA - WM-115 [nTPM]":"72.1","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"8.3","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"8.4","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"7.5","Brain RNA - pons [nTPM]":"9.0","Brain RNA - spinal cord [nTPM]":"9.4","Brain RNA - thalamus [nTPM]":"10.6","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"14.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"3.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"66.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"78.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"19.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"82.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"90.2","Single Cell Type RNA - Early spermatids [nTPM]":"14.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.3","Single Cell Type RNA - Endothelial cells [nTPM]":"20.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"115.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"85.1","Single Cell Type RNA - Fibroblasts [nTPM]":"42.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"82.1","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"26.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"7.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"125.9","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.2","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"60.2","Single Cell Type RNA - Langerhans cells [nTPM]":"44.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"28.6","Single Cell Type RNA - Macrophages [nTPM]":"54.7","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"21.8","Single Cell Type RNA - Muller glia cells [nTPM]":"17.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"179.4","Single Cell Type RNA - Paneth cells [nTPM]":"30.6","Single Cell Type RNA - Peritubular cells [nTPM]":"24.8","Single Cell Type RNA - Plasma cells [nTPM]":"5.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"108.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"51.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.9","Single Cell Type RNA - Spermatocytes [nTPM]":"4.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.3","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"11.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.7","Single Cell Type RNA - Urothelial cells [nTPM]":"103.8"},{"Gene":"ADCY1","Gene synonym":["AC1","DFNB44"],"Ensembl":"ENSG00000164742","Gene description":"Adenylate cyclase 1","Uniprot":["Q08828"],"Chromosome":"7","Position":"45574140-45723116","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","cAMP biosynthesis"],"Molecular function":["Calmodulin-binding","Lyase"],"Disease involvement":["Cancer-related genes","Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"33.7","liver":"19.2","retina":"53.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"521.3","Excitatory neurons":"147.2","Inhibitory neurons":"117.9","Rod photoreceptor cells":"174.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"22.2","SH-SY5Y":"25.5","SK-MEL-30":"30.1","WM-115":"17.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018364","HPA068274"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB018364":"AB_2223098","HPA068274":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"22.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"4.7","Tissue RNA - cerebellum [nTPM]":"15.4","Tissue RNA - cerebral cortex [nTPM]":"33.7","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"2.0","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"31.9","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"19.2","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"1.9","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"53.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"8.5","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"24.5","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"5.9","Cell RNA - AF22 [nTPM]":"2.1","Cell RNA - AN3-CA [nTPM]":"3.2","Cell RNA - ASC diff [nTPM]":"4.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"5.8","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"10.7","Cell RNA - HEK 293 [nTPM]":"2.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"2.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"22.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"8.6","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"7.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"7.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"8.3","Cell RNA - OE19 [nTPM]":"5.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"11.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"5.7","Cell RNA - SCLC-21H [nTPM]":"13.4","Cell RNA - SH-SY5Y [nTPM]":"25.5","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"30.1","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"17.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"22.4","Brain RNA - cerebellum [nTPM]":"15.4","Brain RNA - cerebral cortex [nTPM]":"33.7","Brain RNA - hippocampal formation [nTPM]":"31.9","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"24.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"30.7","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"43.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"521.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"147.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"52.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"117.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"13.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"63.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"174.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"ADCY5","Gene synonym":["AC5"],"Ensembl":"ENSG00000173175","Gene description":"Adenylate cyclase 5","Uniprot":["O95622"],"Chromosome":"3","Position":"123282296-123449090","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"97.7","heart muscle":"105.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"75.5","Inhibitory neurons":"44.0","Oligodendrocytes":"89.7","Paneth cells":"59.6","Peritubular cells":"73.7","Sertoli cells":"65.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"15.5","RPMI-8226":"2.7","RPTEC TERT1":"5.2"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"388.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"155.9"},"Antibody":["HPA017730","HPA077682"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA017730":"AB_1844595","HPA077682":"AB_2686851"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.46e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-4"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"3.3","Tissue RNA - amygdala [nTPM]":"25.5","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"97.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"13.9","Tissue RNA - cerebral cortex [nTPM]":"43.9","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"35.1","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"14.7","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"18.8","Tissue RNA - fallopian tube [nTPM]":"12.7","Tissue RNA - gallbladder [nTPM]":"10.0","Tissue RNA - heart muscle [nTPM]":"105.2","Tissue RNA - hippocampal formation [nTPM]":"25.8","Tissue RNA - hypothalamus [nTPM]":"15.9","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"3.3","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"20.5","Tissue RNA - midbrain [nTPM]":"18.3","Tissue RNA - ovary [nTPM]":"13.2","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"14.3","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"17.4","Tissue RNA - prostate [nTPM]":"19.8","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"21.5","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"13.0","Tissue RNA - smooth muscle [nTPM]":"18.2","Tissue RNA - spinal cord [nTPM]":"10.8","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"21.2","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"34.4","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"23.2","Tissue RNA - vagina [nTPM]":"7.8","Tissue RNA - white matter [nTPM]":"30.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"2.3","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"15.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"2.7","Cell RNA - RPTEC TERT1 [nTPM]":"5.2","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"1.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"25.5","Brain RNA - basal ganglia [nTPM]":"97.7","Brain RNA - cerebellum [nTPM]":"13.9","Brain RNA - cerebral cortex [nTPM]":"43.9","Brain RNA - hippocampal formation [nTPM]":"25.8","Brain RNA - hypothalamus [nTPM]":"15.9","Brain RNA - medulla oblongata [nTPM]":"20.5","Brain RNA - midbrain [nTPM]":"18.3","Brain RNA - pons [nTPM]":"17.4","Brain RNA - spinal cord [nTPM]":"10.8","Brain RNA - thalamus [nTPM]":"34.4","Brain RNA - white matter [nTPM]":"30.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"21.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"75.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"15.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"44.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"89.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"59.6","Single Cell Type RNA - Peritubular cells [nTPM]":"73.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ADD3","Gene synonym":["ADDL"],"Ensembl":"ENSG00000148700","Gene description":"Adducin 3","Uniprot":["Q9UEY8"],"Chromosome":"10","Position":"109996368-110135565","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding","Calmodulin-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"449.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"313.2","ASC TERT1":"292.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009797","HPA035696"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB009797":"AB_2223583","HPA035696":"AB_2674740"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"57.7","Tissue RNA - adrenal gland [nTPM]":"21.7","Tissue RNA - amygdala [nTPM]":"105.6","Tissue RNA - appendix [nTPM]":"38.8","Tissue RNA - basal ganglia [nTPM]":"97.2","Tissue RNA - bone marrow [nTPM]":"37.5","Tissue RNA - breast [nTPM]":"89.4","Tissue RNA - cerebellum [nTPM]":"88.6","Tissue RNA - cerebral cortex [nTPM]":"129.3","Tissue RNA - cervix [nTPM]":"57.6","Tissue RNA - choroid plexus [nTPM]":"65.9","Tissue RNA - colon [nTPM]":"58.2","Tissue RNA - duodenum [nTPM]":"71.9","Tissue RNA - endometrium 1 [nTPM]":"24.9","Tissue RNA - epididymis [nTPM]":"62.4","Tissue RNA - esophagus [nTPM]":"39.0","Tissue RNA - fallopian tube [nTPM]":"47.6","Tissue RNA - gallbladder [nTPM]":"72.0","Tissue RNA - heart muscle [nTPM]":"59.9","Tissue RNA - hippocampal formation [nTPM]":"113.3","Tissue RNA - hypothalamus [nTPM]":"108.1","Tissue RNA - kidney [nTPM]":"102.7","Tissue RNA - liver [nTPM]":"27.8","Tissue RNA - lung [nTPM]":"38.4","Tissue RNA - lymph node [nTPM]":"70.9","Tissue RNA - medulla oblongata [nTPM]":"107.3","Tissue RNA - midbrain [nTPM]":"94.8","Tissue RNA - ovary [nTPM]":"46.4","Tissue RNA - pancreas [nTPM]":"67.9","Tissue RNA - parathyroid gland [nTPM]":"18.8","Tissue RNA - pituitary gland [nTPM]":"25.3","Tissue RNA - placenta [nTPM]":"36.6","Tissue RNA - pons [nTPM]":"102.0","Tissue RNA - prostate [nTPM]":"32.7","Tissue RNA - rectum [nTPM]":"66.0","Tissue RNA - retina [nTPM]":"99.4","Tissue RNA - salivary gland [nTPM]":"59.1","Tissue RNA - seminal vesicle [nTPM]":"31.8","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"33.6","Tissue RNA - small intestine [nTPM]":"85.4","Tissue RNA - smooth muscle [nTPM]":"23.9","Tissue RNA - spinal cord [nTPM]":"105.2","Tissue RNA - spleen [nTPM]":"40.0","Tissue RNA - stomach 1 [nTPM]":"63.7","Tissue RNA - testis [nTPM]":"51.5","Tissue RNA - thalamus [nTPM]":"95.6","Tissue RNA - thymus [nTPM]":"87.4","Tissue RNA - thyroid gland [nTPM]":"87.7","Tissue RNA - tongue [nTPM]":"25.6","Tissue RNA - tonsil [nTPM]":"65.4","Tissue RNA - urinary bladder [nTPM]":"42.3","Tissue RNA - vagina [nTPM]":"40.1","Tissue RNA - white matter [nTPM]":"122.4","Cell RNA - A-431 [nTPM]":"29.2","Cell RNA - A549 [nTPM]":"6.0","Cell RNA - AF22 [nTPM]":"41.7","Cell RNA - AN3-CA [nTPM]":"19.8","Cell RNA - ASC diff [nTPM]":"313.2","Cell RNA - ASC TERT1 [nTPM]":"292.1","Cell RNA - BEWO [nTPM]":"17.7","Cell RNA - BJ [nTPM]":"41.2","Cell RNA - BJ hTERT+ [nTPM]":"110.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.9","Cell RNA - CACO-2 [nTPM]":"60.3","Cell RNA - CAPAN-2 [nTPM]":"90.6","Cell RNA - Daudi [nTPM]":"89.9","Cell RNA - EFO-21 [nTPM]":"45.2","Cell RNA - fHDF\/TERT166 [nTPM]":"63.9","Cell RNA - GAMG [nTPM]":"26.4","Cell RNA - HaCaT [nTPM]":"10.0","Cell RNA - HAP1 [nTPM]":"37.3","Cell RNA - HBEC3-KT [nTPM]":"27.1","Cell RNA - HBF TERT88 [nTPM]":"39.5","Cell RNA - HDLM-2 [nTPM]":"9.0","Cell RNA - HEK 293 [nTPM]":"46.5","Cell RNA - HEL [nTPM]":"8.8","Cell RNA - HeLa [nTPM]":"28.5","Cell RNA - Hep G2 [nTPM]":"45.9","Cell RNA - HHSteC [nTPM]":"35.5","Cell RNA - HL-60 [nTPM]":"30.5","Cell RNA - HMC-1 [nTPM]":"66.0","Cell RNA - HSkMC [nTPM]":"142.5","Cell RNA - hTCEpi [nTPM]":"12.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.3","Cell RNA - hTERT-HME1 [nTPM]":"2.6","Cell RNA - hTERT-RPE1 [nTPM]":"96.4","Cell RNA - HUVEC TERT2 [nTPM]":"37.8","Cell RNA - JURKAT [nTPM]":"109.9","Cell RNA - K-562 [nTPM]":"23.5","Cell RNA - Karpas-707 [nTPM]":"48.7","Cell RNA - LHCN-M2 [nTPM]":"46.7","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"32.3","Cell RNA - NB-4 [nTPM]":"31.0","Cell RNA - NTERA-2 [nTPM]":"25.8","Cell RNA - OE19 [nTPM]":"69.2","Cell RNA - PC-3 [nTPM]":"15.3","Cell RNA - REH [nTPM]":"27.7","Cell RNA - RH-30 [nTPM]":"58.2","Cell RNA - RPMI-8226 [nTPM]":"4.8","Cell RNA - RPTEC TERT1 [nTPM]":"65.7","Cell RNA - RT4 [nTPM]":"14.2","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"67.9","Cell RNA - SiHa [nTPM]":"27.6","Cell RNA - SK-BR-3 [nTPM]":"8.9","Cell RNA - SK-MEL-30 [nTPM]":"66.5","Cell RNA - SuSa [nTPM]":"62.2","Cell RNA - T-47d [nTPM]":"10.7","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"9.5","Cell RNA - U-138 MG [nTPM]":"16.0","Cell RNA - U-2 OS [nTPM]":"42.0","Cell RNA - U-2197 [nTPM]":"33.5","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"68.9","Cell RNA - U-266\/84 [nTPM]":"31.5","Cell RNA - U-698 [nTPM]":"82.7","Cell RNA - U-87 MG [nTPM]":"47.8","Cell RNA - U-937 [nTPM]":"16.2","Cell RNA - WM-115 [nTPM]":"27.7","Blood RNA - basophil [nTPM]":"139.5","Blood RNA - classical monocyte [nTPM]":"29.6","Blood RNA - eosinophil [nTPM]":"98.0","Blood RNA - gdT-cell [nTPM]":"68.8","Blood RNA - intermediate monocyte [nTPM]":"26.5","Blood RNA - MAIT T-cell [nTPM]":"55.7","Blood RNA - memory B-cell [nTPM]":"51.4","Blood RNA - memory CD4 T-cell [nTPM]":"72.9","Blood RNA - memory CD8 T-cell [nTPM]":"59.1","Blood RNA - myeloid DC [nTPM]":"24.8","Blood RNA - naive B-cell [nTPM]":"42.9","Blood RNA - naive CD4 T-cell [nTPM]":"83.2","Blood RNA - naive CD8 T-cell [nTPM]":"67.6","Blood RNA - neutrophil [nTPM]":"47.1","Blood RNA - NK-cell [nTPM]":"73.4","Blood RNA - non-classical monocyte [nTPM]":"32.6","Blood RNA - plasmacytoid DC [nTPM]":"16.3","Blood RNA - T-reg [nTPM]":"73.3","Blood RNA - total PBMC [nTPM]":"94.9","Brain RNA - amygdala [nTPM]":"105.6","Brain RNA - basal ganglia [nTPM]":"97.2","Brain RNA - cerebellum [nTPM]":"88.6","Brain RNA - cerebral cortex [nTPM]":"129.3","Brain RNA - hippocampal formation [nTPM]":"113.3","Brain RNA - hypothalamus [nTPM]":"108.1","Brain RNA - medulla oblongata [nTPM]":"107.3","Brain RNA - midbrain [nTPM]":"94.8","Brain RNA - pons [nTPM]":"102.0","Brain RNA - spinal cord [nTPM]":"105.2","Brain RNA - thalamus [nTPM]":"95.6","Brain RNA - white matter [nTPM]":"122.4","Single Cell Type RNA - Adipocytes [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"52.9","Single Cell Type RNA - Astrocytes [nTPM]":"449.2","Single Cell Type RNA - B-cells [nTPM]":"110.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"55.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"77.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.7","Single Cell Type RNA - Bipolar cells [nTPM]":"26.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"56.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"128.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"74.4","Single Cell Type RNA - Club cells [nTPM]":"85.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.6","Single Cell Type RNA - dendritic cells [nTPM]":"112.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"125.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"27.2","Single Cell Type RNA - Early spermatids [nTPM]":"51.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"70.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"76.0","Single Cell Type RNA - Endothelial cells [nTPM]":"77.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"102.4","Single Cell Type RNA - Erythroid cells [nTPM]":"32.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"83.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"61.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.1","Single Cell Type RNA - Fibroblasts [nTPM]":"182.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"100.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"56.0","Single Cell Type RNA - granulocytes [nTPM]":"26.0","Single Cell Type RNA - Granulosa cells [nTPM]":"18.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"126.7","Single Cell Type RNA - Hepatocytes [nTPM]":"12.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.7","Single Cell Type RNA - Horizontal cells [nTPM]":"116.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"141.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"71.6","Single Cell Type RNA - Ionocytes [nTPM]":"48.8","Single Cell Type RNA - Kupffer cells [nTPM]":"88.5","Single Cell Type RNA - Langerhans cells [nTPM]":"41.1","Single Cell Type RNA - Late spermatids [nTPM]":"25.7","Single Cell Type RNA - Leydig cells [nTPM]":"226.5","Single Cell Type RNA - Macrophages [nTPM]":"66.3","Single Cell Type RNA - Melanocytes [nTPM]":"58.7","Single Cell Type RNA - Microglial cells [nTPM]":"70.3","Single Cell Type RNA - monocytes [nTPM]":"65.3","Single Cell Type RNA - Muller glia cells [nTPM]":"339.0","Single Cell Type RNA - NK-cells [nTPM]":"151.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"236.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"279.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"59.8","Single Cell Type RNA - Paneth cells [nTPM]":"167.1","Single Cell Type RNA - Peritubular cells [nTPM]":"251.3","Single Cell Type RNA - Plasma cells [nTPM]":"68.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"135.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"162.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"151.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"121.7","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.2","Single Cell Type RNA - Spermatocytes [nTPM]":"122.7","Single Cell Type RNA - Spermatogonia [nTPM]":"62.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.3","Single Cell Type RNA - T-cells [nTPM]":"111.5","Single Cell Type RNA - Theca cells [nTPM]":"30.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"166.7","Single Cell Type RNA - Urothelial cells [nTPM]":"98.6"},{"Gene":"ADGRV1","Gene synonym":["DKFZp761P0710","FEB4","GPR98","KIAA0686","MASS1","USH2C","VLGR1"],"Ensembl":"ENSG00000164199","Gene description":"Adhesion G protein-coupled receptor V1","Uniprot":["Q8WXG9"],"Chromosome":"5","Position":"90529344-91164437","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Hydrolase","Receptor","Transducer"],"Disease involvement":["Deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"adrenal gland":"533.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"2207.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"15.5","HAP1":"23.0","K-562":"9.8","NTERA-2":"11.6","SCLC-21H":"11.1","SuSa":"15.0","U-266\/70":"13.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067503"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA067503":"AB_2685856"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"533.0","Tissue RNA - amygdala [nTPM]":"36.9","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"47.8","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"40.3","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"22.4","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"12.3","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"39.1","Tissue RNA - hypothalamus [nTPM]":"11.6","Tissue RNA - kidney [nTPM]":"21.5","Tissue RNA - liver [nTPM]":"42.3","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"12.8","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"15.1","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"18.2","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"18.3","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"17.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"26.1","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"15.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"23.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"4.1","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"9.8","Cell RNA - Karpas-707 [nTPM]":"2.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"11.6","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"4.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"11.1","Cell RNA - SH-SY5Y [nTPM]":"2.7","Cell RNA - SiHa [nTPM]":"3.4","Cell RNA - SK-BR-3 [nTPM]":"2.2","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"15.0","Cell RNA - T-47d [nTPM]":"5.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"13.4","Cell RNA - U-266\/84 [nTPM]":"4.1","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"4.6","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"36.9","Brain RNA - basal ganglia [nTPM]":"47.8","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"40.3","Brain RNA - hippocampal formation [nTPM]":"39.1","Brain RNA - hypothalamus [nTPM]":"11.6","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"12.8","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"18.3","Brain RNA - white matter [nTPM]":"26.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.5","Single Cell Type RNA - Astrocytes [nTPM]":"2207.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"28.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"264.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"43.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"54.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.6","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"12.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"54.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"84.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.0"},{"Gene":"AFG3L2","Gene synonym":["SCA28","SPAX5"],"Ensembl":"ENSG00000141385","Gene description":"AFG3 like matrix AAA peptidase subunit 2","Uniprot":["Q9Y4W6"],"Chromosome":"18","Position":"12328944-12377227","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004479","HPA004480"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA004479":"AB_1078109","HPA004480":"AB_1078108"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.68e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.05e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.1","Tissue RNA - adrenal gland [nTPM]":"25.9","Tissue RNA - amygdala [nTPM]":"16.4","Tissue RNA - appendix [nTPM]":"21.9","Tissue RNA - basal ganglia [nTPM]":"17.0","Tissue RNA - bone marrow [nTPM]":"32.4","Tissue RNA - breast [nTPM]":"29.2","Tissue RNA - cerebellum [nTPM]":"18.2","Tissue RNA - cerebral cortex [nTPM]":"19.0","Tissue RNA - cervix [nTPM]":"24.1","Tissue RNA - choroid plexus [nTPM]":"30.8","Tissue RNA - colon [nTPM]":"60.8","Tissue RNA - duodenum [nTPM]":"79.9","Tissue RNA - endometrium 1 [nTPM]":"22.1","Tissue RNA - epididymis [nTPM]":"17.5","Tissue RNA - esophagus [nTPM]":"41.5","Tissue RNA - fallopian tube [nTPM]":"23.8","Tissue RNA - gallbladder [nTPM]":"18.3","Tissue RNA - heart muscle [nTPM]":"88.0","Tissue RNA - hippocampal formation [nTPM]":"17.0","Tissue RNA - hypothalamus [nTPM]":"18.7","Tissue RNA - kidney [nTPM]":"62.7","Tissue RNA - liver [nTPM]":"51.0","Tissue RNA - lung [nTPM]":"21.8","Tissue RNA - lymph node [nTPM]":"23.7","Tissue RNA - medulla oblongata [nTPM]":"17.7","Tissue RNA - midbrain [nTPM]":"16.6","Tissue RNA - ovary [nTPM]":"24.1","Tissue RNA - pancreas [nTPM]":"41.1","Tissue RNA - parathyroid gland [nTPM]":"76.0","Tissue RNA - pituitary gland [nTPM]":"18.6","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"18.8","Tissue RNA - prostate [nTPM]":"24.6","Tissue RNA - rectum [nTPM]":"54.1","Tissue RNA - retina [nTPM]":"20.3","Tissue RNA - salivary gland [nTPM]":"30.8","Tissue RNA - seminal vesicle [nTPM]":"24.4","Tissue RNA - skeletal muscle [nTPM]":"145.4","Tissue RNA - skin 1 [nTPM]":"29.8","Tissue RNA - small intestine [nTPM]":"58.7","Tissue RNA - smooth muscle [nTPM]":"25.4","Tissue RNA - spinal cord [nTPM]":"15.8","Tissue RNA - spleen [nTPM]":"18.5","Tissue RNA - stomach 1 [nTPM]":"39.1","Tissue RNA - testis [nTPM]":"18.5","Tissue RNA - thalamus [nTPM]":"19.0","Tissue RNA - thymus [nTPM]":"24.3","Tissue RNA - thyroid gland [nTPM]":"39.2","Tissue RNA - tongue [nTPM]":"155.8","Tissue RNA - tonsil [nTPM]":"31.0","Tissue RNA - urinary bladder [nTPM]":"30.9","Tissue RNA - vagina [nTPM]":"19.6","Tissue RNA - white matter [nTPM]":"17.6","Cell RNA - A-431 [nTPM]":"56.5","Cell RNA - A549 [nTPM]":"56.6","Cell RNA - AF22 [nTPM]":"39.7","Cell RNA - AN3-CA [nTPM]":"44.8","Cell RNA - ASC diff [nTPM]":"45.2","Cell RNA - ASC TERT1 [nTPM]":"48.6","Cell RNA - BEWO [nTPM]":"52.7","Cell RNA - BJ [nTPM]":"61.9","Cell RNA - BJ hTERT+ [nTPM]":"61.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"86.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"63.1","Cell RNA - CACO-2 [nTPM]":"88.1","Cell RNA - CAPAN-2 [nTPM]":"34.1","Cell RNA - Daudi [nTPM]":"161.3","Cell RNA - EFO-21 [nTPM]":"66.3","Cell RNA - fHDF\/TERT166 [nTPM]":"56.6","Cell RNA - GAMG [nTPM]":"76.8","Cell RNA - HaCaT [nTPM]":"55.6","Cell RNA - HAP1 [nTPM]":"101.4","Cell RNA - HBEC3-KT [nTPM]":"71.3","Cell RNA - HBF TERT88 [nTPM]":"70.3","Cell RNA - HDLM-2 [nTPM]":"38.1","Cell RNA - HEK 293 [nTPM]":"43.5","Cell RNA - HEL [nTPM]":"48.5","Cell RNA - HeLa [nTPM]":"59.3","Cell RNA - Hep G2 [nTPM]":"83.5","Cell RNA - HHSteC [nTPM]":"61.1","Cell RNA - HL-60 [nTPM]":"185.0","Cell RNA - HMC-1 [nTPM]":"69.8","Cell RNA - HSkMC [nTPM]":"54.3","Cell RNA - hTCEpi [nTPM]":"76.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"82.1","Cell RNA - hTERT-HME1 [nTPM]":"107.7","Cell RNA - hTERT-RPE1 [nTPM]":"47.8","Cell RNA - HUVEC TERT2 [nTPM]":"64.0","Cell RNA - JURKAT [nTPM]":"57.0","Cell RNA - K-562 [nTPM]":"111.3","Cell RNA - Karpas-707 [nTPM]":"92.8","Cell RNA - LHCN-M2 [nTPM]":"43.6","Cell RNA - MCF7 [nTPM]":"89.0","Cell RNA - MOLT-4 [nTPM]":"66.7","Cell RNA - NB-4 [nTPM]":"58.5","Cell RNA - NTERA-2 [nTPM]":"55.3","Cell RNA - OE19 [nTPM]":"277.4","Cell RNA - PC-3 [nTPM]":"41.9","Cell RNA - REH [nTPM]":"74.0","Cell RNA - RH-30 [nTPM]":"125.1","Cell RNA - RPMI-8226 [nTPM]":"135.2","Cell RNA - RPTEC TERT1 [nTPM]":"74.9","Cell RNA - RT4 [nTPM]":"123.6","Cell RNA - SCLC-21H [nTPM]":"73.7","Cell RNA - SH-SY5Y [nTPM]":"51.3","Cell RNA - SiHa [nTPM]":"97.0","Cell RNA - SK-BR-3 [nTPM]":"103.8","Cell RNA - SK-MEL-30 [nTPM]":"90.0","Cell RNA - SuSa [nTPM]":"50.5","Cell RNA - T-47d [nTPM]":"47.8","Cell RNA - THP-1 [nTPM]":"84.5","Cell RNA - TIME [nTPM]":"49.0","Cell RNA - U-138 MG [nTPM]":"102.4","Cell RNA - U-2 OS [nTPM]":"88.6","Cell RNA - U-2197 [nTPM]":"98.7","Cell RNA - U-251 MG [nTPM]":"81.7","Cell RNA - U-266\/70 [nTPM]":"64.7","Cell RNA - U-266\/84 [nTPM]":"80.7","Cell RNA - U-698 [nTPM]":"104.1","Cell RNA - U-87 MG [nTPM]":"56.2","Cell RNA - U-937 [nTPM]":"71.4","Cell RNA - WM-115 [nTPM]":"48.0","Blood RNA - basophil [nTPM]":"3.8","Blood RNA - classical monocyte [nTPM]":"16.5","Blood RNA - eosinophil [nTPM]":"12.4","Blood RNA - gdT-cell [nTPM]":"11.6","Blood RNA - intermediate monocyte [nTPM]":"17.6","Blood RNA - MAIT T-cell [nTPM]":"13.9","Blood RNA - memory B-cell [nTPM]":"14.0","Blood RNA - memory CD4 T-cell [nTPM]":"13.8","Blood RNA - memory CD8 T-cell [nTPM]":"17.9","Blood RNA - myeloid DC [nTPM]":"21.8","Blood RNA - naive B-cell [nTPM]":"10.3","Blood RNA - naive CD4 T-cell [nTPM]":"17.2","Blood RNA - naive CD8 T-cell [nTPM]":"20.2","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"28.4","Blood RNA - non-classical monocyte [nTPM]":"16.2","Blood RNA - plasmacytoid DC [nTPM]":"11.5","Blood RNA - T-reg [nTPM]":"9.5","Blood RNA - total PBMC [nTPM]":"13.4","Brain RNA - amygdala [nTPM]":"16.4","Brain RNA - basal ganglia [nTPM]":"17.0","Brain RNA - cerebellum [nTPM]":"18.2","Brain RNA - cerebral cortex [nTPM]":"19.0","Brain RNA - hippocampal formation [nTPM]":"17.0","Brain RNA - hypothalamus [nTPM]":"18.7","Brain RNA - medulla oblongata [nTPM]":"17.7","Brain RNA - midbrain [nTPM]":"16.6","Brain RNA - pons [nTPM]":"18.8","Brain RNA - spinal cord [nTPM]":"15.8","Brain RNA - thalamus [nTPM]":"19.0","Brain RNA - white matter [nTPM]":"17.6","Single Cell Type RNA - Adipocytes [nTPM]":"24.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.2","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"36.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.7","Single Cell Type RNA - Bipolar cells [nTPM]":"50.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"74.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"28.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"58.5","Single Cell Type RNA - dendritic cells [nTPM]":"29.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"85.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"72.4","Single Cell Type RNA - Ductal cells [nTPM]":"39.5","Single Cell Type RNA - Early spermatids [nTPM]":"5.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.3","Single Cell Type RNA - Endothelial cells [nTPM]":"27.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"39.1","Single Cell Type RNA - Erythroid cells [nTPM]":"61.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.9","Single Cell Type RNA - Fibroblasts [nTPM]":"31.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"53.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.1","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"41.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"85.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.0","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"82.6","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"32.6","Single Cell Type RNA - Langerhans cells [nTPM]":"14.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"32.9","Single Cell Type RNA - Macrophages [nTPM]":"34.2","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"27.6","Single Cell Type RNA - Muller glia cells [nTPM]":"26.9","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.8","Single Cell Type RNA - Paneth cells [nTPM]":"43.1","Single Cell Type RNA - Peritubular cells [nTPM]":"30.1","Single Cell Type RNA - Plasma cells [nTPM]":"38.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"88.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"100.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"53.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.9","Single Cell Type RNA - Spermatocytes [nTPM]":"50.9","Single Cell Type RNA - Spermatogonia [nTPM]":"65.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"75.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"92.8","Single Cell Type RNA - T-cells [nTPM]":"28.4","Single Cell Type RNA - Theca cells [nTPM]":"60.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"94.9","Single Cell Type RNA - Urothelial cells [nTPM]":"38.2"},{"Gene":"AGBL1","Gene synonym":["CCP4","FLJ32310"],"Ensembl":"ENSG00000273540","Gene description":"ATP\/GTP binding protein like 1","Uniprot":["Q96MI9"],"Chromosome":"15","Position":"86079871-87049169","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Corneal dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"skeletal muscle":"7.8","tongue":"23.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"16.7","Astrocytes":"28.7","Excitatory neurons":"15.6","Inhibitory neurons":"25.6","Oligodendrocyte precursor cells":"47.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"23.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.7","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"47.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"AGBL5","Gene synonym":["CCP5","FLJ21839"],"Ensembl":"ENSG00000084693","Gene description":"ATP\/GTP binding protein like 5","Uniprot":["Q8NDL9"],"Chromosome":"2","Position":"27042364-27070622","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"parathyroid gland":"49.9","testis":"192.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"302.7","Late spermatids":"338.0","Spermatocytes":"156.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030981"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytokinetic bridge"],"Subcellular additional location":["Microtubules","Cytosol"],"Antibody RRID":{"HPA030981":"AB_10611673"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.87e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"16.7","Tissue RNA - amygdala [nTPM]":"8.4","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"13.6","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"8.2","Tissue RNA - cervix [nTPM]":"14.4","Tissue RNA - choroid plexus [nTPM]":"9.5","Tissue RNA - colon [nTPM]":"16.2","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"14.0","Tissue RNA - epididymis [nTPM]":"26.0","Tissue RNA - esophagus [nTPM]":"18.3","Tissue RNA - fallopian tube [nTPM]":"20.8","Tissue RNA - gallbladder [nTPM]":"14.3","Tissue RNA - heart muscle [nTPM]":"12.7","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"22.5","Tissue RNA - liver [nTPM]":"7.2","Tissue RNA - lung [nTPM]":"11.2","Tissue RNA - lymph node [nTPM]":"10.7","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"14.4","Tissue RNA - pancreas [nTPM]":"15.0","Tissue RNA - parathyroid gland [nTPM]":"49.9","Tissue RNA - pituitary gland [nTPM]":"12.5","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"11.5","Tissue RNA - retina [nTPM]":"16.3","Tissue RNA - salivary gland [nTPM]":"21.2","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"20.5","Tissue RNA - small intestine [nTPM]":"9.9","Tissue RNA - smooth muscle [nTPM]":"14.6","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"8.5","Tissue RNA - stomach 1 [nTPM]":"11.8","Tissue RNA - testis [nTPM]":"192.9","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"15.6","Tissue RNA - thyroid gland [nTPM]":"28.5","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"14.9","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"55.0","Cell RNA - A549 [nTPM]":"34.7","Cell RNA - AF22 [nTPM]":"55.4","Cell RNA - AN3-CA [nTPM]":"37.2","Cell RNA - ASC diff [nTPM]":"11.6","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"62.9","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"23.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.9","Cell RNA - CACO-2 [nTPM]":"30.2","Cell RNA - CAPAN-2 [nTPM]":"40.5","Cell RNA - Daudi [nTPM]":"30.3","Cell RNA - EFO-21 [nTPM]":"34.0","Cell RNA - fHDF\/TERT166 [nTPM]":"18.9","Cell RNA - GAMG [nTPM]":"43.4","Cell RNA - HaCaT [nTPM]":"24.6","Cell RNA - HAP1 [nTPM]":"44.8","Cell RNA - HBEC3-KT [nTPM]":"49.4","Cell RNA - HBF TERT88 [nTPM]":"33.9","Cell RNA - HDLM-2 [nTPM]":"25.9","Cell RNA - HEK 293 [nTPM]":"66.8","Cell RNA - HEL [nTPM]":"44.5","Cell RNA - HeLa [nTPM]":"42.0","Cell RNA - Hep G2 [nTPM]":"65.7","Cell RNA - HHSteC [nTPM]":"23.6","Cell RNA - HL-60 [nTPM]":"21.6","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"24.4","Cell RNA - hTCEpi [nTPM]":"36.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.1","Cell RNA - hTERT-HME1 [nTPM]":"22.0","Cell RNA - hTERT-RPE1 [nTPM]":"46.9","Cell RNA - HUVEC TERT2 [nTPM]":"32.8","Cell RNA - JURKAT [nTPM]":"43.5","Cell RNA - K-562 [nTPM]":"38.9","Cell RNA - Karpas-707 [nTPM]":"23.8","Cell RNA - LHCN-M2 [nTPM]":"30.3","Cell RNA - MCF7 [nTPM]":"21.5","Cell RNA - MOLT-4 [nTPM]":"63.2","Cell RNA - NB-4 [nTPM]":"32.3","Cell RNA - NTERA-2 [nTPM]":"39.4","Cell RNA - OE19 [nTPM]":"39.4","Cell RNA - PC-3 [nTPM]":"23.7","Cell RNA - REH [nTPM]":"64.5","Cell RNA - RH-30 [nTPM]":"62.9","Cell RNA - RPMI-8226 [nTPM]":"48.0","Cell RNA - RPTEC TERT1 [nTPM]":"31.9","Cell RNA - RT4 [nTPM]":"13.6","Cell RNA - SCLC-21H [nTPM]":"37.1","Cell RNA - SH-SY5Y [nTPM]":"53.6","Cell RNA - SiHa [nTPM]":"21.5","Cell RNA - SK-BR-3 [nTPM]":"16.7","Cell RNA - SK-MEL-30 [nTPM]":"35.0","Cell RNA - SuSa [nTPM]":"53.9","Cell RNA - T-47d [nTPM]":"24.9","Cell RNA - THP-1 [nTPM]":"16.3","Cell RNA - TIME [nTPM]":"16.4","Cell RNA - U-138 MG [nTPM]":"28.6","Cell RNA - U-2 OS [nTPM]":"39.2","Cell RNA - U-2197 [nTPM]":"13.8","Cell RNA - U-251 MG [nTPM]":"23.9","Cell RNA - U-266\/70 [nTPM]":"47.7","Cell RNA - U-266\/84 [nTPM]":"27.2","Cell RNA - U-698 [nTPM]":"62.4","Cell RNA - U-87 MG [nTPM]":"31.8","Cell RNA - U-937 [nTPM]":"24.4","Cell RNA - WM-115 [nTPM]":"26.1","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"4.5","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"4.6","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"4.1","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"8.5","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"3.8","Brain RNA - amygdala [nTPM]":"8.4","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"8.2","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.7","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"8.3","Single Cell Type RNA - Early spermatids [nTPM]":"302.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.9","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.9","Single Cell Type RNA - Fibroblasts [nTPM]":"6.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"4.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"338.0","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"17.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.0","Single Cell Type RNA - Spermatocytes [nTPM]":"156.8","Single Cell Type RNA - Spermatogonia [nTPM]":"41.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"9.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.6","Single Cell Type RNA - Urothelial cells [nTPM]":"10.5"},{"Gene":"AGK","Gene synonym":["FLJ10842","MULK"],"Ensembl":"ENSG00000006530","Gene description":"Acylglycerol kinase","Uniprot":["Q53H12"],"Chromosome":"7","Position":"141551278-141655244","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Cardiomyopathy","Cataract","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"43.4","Inhibitory neurons":"43.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"97.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020959","HPA053471"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA020959":"AB_1854206","HPA053471":"AB_2682164"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.1","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"8.5","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"11.9","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"5.9","Tissue RNA - endometrium 1 [nTPM]":"11.7","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"12.2","Tissue RNA - fallopian tube [nTPM]":"12.2","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"30.4","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"15.7","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"12.1","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"8.8","Tissue RNA - ovary [nTPM]":"11.3","Tissue RNA - pancreas [nTPM]":"10.1","Tissue RNA - parathyroid gland [nTPM]":"21.5","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"9.0","Tissue RNA - prostate [nTPM]":"12.8","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"12.7","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"12.0","Tissue RNA - smooth muscle [nTPM]":"15.4","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"16.6","Tissue RNA - stomach 1 [nTPM]":"12.2","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"14.0","Tissue RNA - thyroid gland [nTPM]":"12.7","Tissue RNA - tongue [nTPM]":"10.0","Tissue RNA - tonsil [nTPM]":"14.7","Tissue RNA - urinary bladder [nTPM]":"10.8","Tissue RNA - vagina [nTPM]":"11.5","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"23.7","Cell RNA - A549 [nTPM]":"25.6","Cell RNA - AF22 [nTPM]":"26.7","Cell RNA - AN3-CA [nTPM]":"21.8","Cell RNA - ASC diff [nTPM]":"21.2","Cell RNA - ASC TERT1 [nTPM]":"29.4","Cell RNA - BEWO [nTPM]":"16.2","Cell RNA - BJ [nTPM]":"23.5","Cell RNA - BJ hTERT+ [nTPM]":"29.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"50.9","Cell RNA - CACO-2 [nTPM]":"24.7","Cell RNA - CAPAN-2 [nTPM]":"18.3","Cell RNA - Daudi [nTPM]":"26.3","Cell RNA - EFO-21 [nTPM]":"24.0","Cell RNA - fHDF\/TERT166 [nTPM]":"26.8","Cell RNA - GAMG [nTPM]":"40.5","Cell RNA - HaCaT [nTPM]":"18.7","Cell RNA - HAP1 [nTPM]":"41.6","Cell RNA - HBEC3-KT [nTPM]":"32.8","Cell RNA - HBF TERT88 [nTPM]":"51.0","Cell RNA - HDLM-2 [nTPM]":"33.8","Cell RNA - HEK 293 [nTPM]":"32.7","Cell RNA - HEL [nTPM]":"26.1","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"18.7","Cell RNA - HHSteC [nTPM]":"34.1","Cell RNA - HL-60 [nTPM]":"15.6","Cell RNA - HMC-1 [nTPM]":"12.5","Cell RNA - HSkMC [nTPM]":"29.9","Cell RNA - hTCEpi [nTPM]":"26.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.3","Cell RNA - hTERT-HME1 [nTPM]":"33.1","Cell RNA - hTERT-RPE1 [nTPM]":"19.8","Cell RNA - HUVEC TERT2 [nTPM]":"34.1","Cell RNA - JURKAT [nTPM]":"32.3","Cell RNA - K-562 [nTPM]":"36.3","Cell RNA - Karpas-707 [nTPM]":"36.9","Cell RNA - LHCN-M2 [nTPM]":"25.3","Cell RNA - MCF7 [nTPM]":"24.6","Cell RNA - MOLT-4 [nTPM]":"47.3","Cell RNA - NB-4 [nTPM]":"9.1","Cell RNA - NTERA-2 [nTPM]":"25.6","Cell RNA - OE19 [nTPM]":"19.9","Cell RNA - PC-3 [nTPM]":"32.4","Cell RNA - REH [nTPM]":"29.2","Cell RNA - RH-30 [nTPM]":"4.2","Cell RNA - RPMI-8226 [nTPM]":"80.1","Cell RNA - RPTEC TERT1 [nTPM]":"33.1","Cell RNA - RT4 [nTPM]":"20.8","Cell RNA - SCLC-21H [nTPM]":"23.3","Cell RNA - SH-SY5Y [nTPM]":"29.6","Cell RNA - SiHa [nTPM]":"24.6","Cell RNA - SK-BR-3 [nTPM]":"29.7","Cell RNA - SK-MEL-30 [nTPM]":"27.1","Cell RNA - SuSa [nTPM]":"26.1","Cell RNA - T-47d [nTPM]":"16.3","Cell RNA - THP-1 [nTPM]":"20.2","Cell RNA - TIME [nTPM]":"19.5","Cell RNA - U-138 MG [nTPM]":"18.9","Cell RNA - U-2 OS [nTPM]":"14.1","Cell RNA - U-2197 [nTPM]":"23.8","Cell RNA - U-251 MG [nTPM]":"38.1","Cell RNA - U-266\/70 [nTPM]":"29.5","Cell RNA - U-266\/84 [nTPM]":"31.9","Cell RNA - U-698 [nTPM]":"14.4","Cell RNA - U-87 MG [nTPM]":"30.7","Cell RNA - U-937 [nTPM]":"9.1","Cell RNA - WM-115 [nTPM]":"50.4","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"7.1","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"22.1","Blood RNA - intermediate monocyte [nTPM]":"13.9","Blood RNA - MAIT T-cell [nTPM]":"15.3","Blood RNA - memory B-cell [nTPM]":"10.8","Blood RNA - memory CD4 T-cell [nTPM]":"17.3","Blood RNA - memory CD8 T-cell [nTPM]":"26.0","Blood RNA - myeloid DC [nTPM]":"16.2","Blood RNA - naive B-cell [nTPM]":"6.5","Blood RNA - naive CD4 T-cell [nTPM]":"12.8","Blood RNA - naive CD8 T-cell [nTPM]":"23.5","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"97.3","Blood RNA - non-classical monocyte [nTPM]":"8.2","Blood RNA - plasmacytoid DC [nTPM]":"6.3","Blood RNA - T-reg [nTPM]":"18.9","Blood RNA - total PBMC [nTPM]":"15.7","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"8.8","Brain RNA - pons [nTPM]":"9.0","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"11.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"6.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - dendritic cells [nTPM]":"15.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"11.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.2","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.6","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"9.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"4.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.9","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.1","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"12.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"12.4","Single Cell Type RNA - Muller glia cells [nTPM]":"11.2","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"22.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.0","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - T-cells [nTPM]":"15.0","Single Cell Type RNA - Theca cells [nTPM]":"14.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"AGRN","Gene synonym":["AGRIN"],"Ensembl":"ENSG00000188157","Gene description":"Agrin","Uniprot":["O00468"],"Chromosome":"1","Position":"1020120-1056118","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"94.5","Collecting duct cells":"156.3","Ductal cells":"91.2","Pancreatic endocrine cells":"87.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"205.3","EFO-21":"236.9","HaCaT":"210.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040090"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA040090":"AB_10805603"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"2.7","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"13.9","Tissue RNA - cervix [nTPM]":"14.4","Tissue RNA - choroid plexus [nTPM]":"8.9","Tissue RNA - colon [nTPM]":"10.9","Tissue RNA - duodenum [nTPM]":"7.9","Tissue RNA - endometrium 1 [nTPM]":"13.7","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"14.6","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"44.0","Tissue RNA - liver [nTPM]":"13.3","Tissue RNA - lung [nTPM]":"19.8","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"28.0","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"8.3","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"14.4","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"24.8","Tissue RNA - seminal vesicle [nTPM]":"8.2","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"16.5","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"13.4","Tissue RNA - testis [nTPM]":"9.7","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"34.7","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"16.2","Tissue RNA - vagina [nTPM]":"11.6","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"124.3","Cell RNA - A549 [nTPM]":"75.1","Cell RNA - AF22 [nTPM]":"11.1","Cell RNA - AN3-CA [nTPM]":"42.7","Cell RNA - ASC diff [nTPM]":"2.4","Cell RNA - ASC TERT1 [nTPM]":"3.0","Cell RNA - BEWO [nTPM]":"122.1","Cell RNA - BJ [nTPM]":"61.4","Cell RNA - BJ hTERT+ [nTPM]":"19.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.5","Cell RNA - CACO-2 [nTPM]":"60.6","Cell RNA - CAPAN-2 [nTPM]":"205.3","Cell RNA - Daudi [nTPM]":"2.3","Cell RNA - EFO-21 [nTPM]":"236.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.6","Cell RNA - GAMG [nTPM]":"19.3","Cell RNA - HaCaT [nTPM]":"210.1","Cell RNA - HAP1 [nTPM]":"4.1","Cell RNA - HBEC3-KT [nTPM]":"75.6","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"4.4","Cell RNA - HEK 293 [nTPM]":"28.6","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"102.1","Cell RNA - Hep G2 [nTPM]":"54.2","Cell RNA - HHSteC [nTPM]":"17.1","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"23.1","Cell RNA - HSkMC [nTPM]":"10.5","Cell RNA - hTCEpi [nTPM]":"32.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.6","Cell RNA - hTERT-HME1 [nTPM]":"27.7","Cell RNA - hTERT-RPE1 [nTPM]":"55.9","Cell RNA - HUVEC TERT2 [nTPM]":"7.2","Cell RNA - JURKAT [nTPM]":"1.7","Cell RNA - K-562 [nTPM]":"25.7","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"3.5","Cell RNA - MCF7 [nTPM]":"93.0","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"17.6","Cell RNA - NTERA-2 [nTPM]":"28.4","Cell RNA - OE19 [nTPM]":"39.7","Cell RNA - PC-3 [nTPM]":"54.5","Cell RNA - REH [nTPM]":"20.1","Cell RNA - RH-30 [nTPM]":"27.0","Cell RNA - RPMI-8226 [nTPM]":"18.5","Cell RNA - RPTEC TERT1 [nTPM]":"70.0","Cell RNA - RT4 [nTPM]":"51.4","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"25.9","Cell RNA - SiHa [nTPM]":"124.8","Cell RNA - SK-BR-3 [nTPM]":"129.1","Cell RNA - SK-MEL-30 [nTPM]":"121.9","Cell RNA - SuSa [nTPM]":"12.7","Cell RNA - T-47d [nTPM]":"114.8","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"107.8","Cell RNA - U-138 MG [nTPM]":"47.7","Cell RNA - U-2 OS [nTPM]":"169.0","Cell RNA - U-2197 [nTPM]":"6.4","Cell RNA - U-251 MG [nTPM]":"50.6","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"3.5","Cell RNA - U-87 MG [nTPM]":"30.4","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"13.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"13.9","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"27.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.8","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"94.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"42.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"156.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"91.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.0","Single Cell Type RNA - Endothelial cells [nTPM]":"29.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.8","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"13.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"10.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"10.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"87.3","Single Cell Type RNA - Paneth cells [nTPM]":"17.7","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"11.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.3","Single Cell Type RNA - Urothelial cells [nTPM]":"21.2"},{"Gene":"AHR","Gene synonym":["bHLHe76"],"Ensembl":"ENSG00000106546","Gene description":"Aryl hydrocarbon receptor","Uniprot":["P35869"],"Chromosome":"7","Position":"16916359-17346152","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Cell cycle","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Receptor","Repressor"],"Disease involvement":["Cancer-related genes","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"262.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"71.0","hTERT-HME1":"73.8","OE19":"61.2","RT4":"63.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005072","HPA029722","HPA029723"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB005072":"AB_633731","HPA029722":"AB_10599189","HPA029723":"AB_10599025"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.3","Tissue RNA - adrenal gland [nTPM]":"15.0","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"25.8","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"44.1","Tissue RNA - breast [nTPM]":"19.5","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"2.3","Tissue RNA - colon [nTPM]":"13.7","Tissue RNA - duodenum [nTPM]":"16.4","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"17.4","Tissue RNA - fallopian tube [nTPM]":"10.5","Tissue RNA - gallbladder [nTPM]":"33.7","Tissue RNA - heart muscle [nTPM]":"9.5","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"45.0","Tissue RNA - lung [nTPM]":"37.6","Tissue RNA - lymph node [nTPM]":"15.4","Tissue RNA - medulla oblongata [nTPM]":"5.4","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"6.9","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"6.6","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"17.7","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"11.0","Tissue RNA - rectum [nTPM]":"16.3","Tissue RNA - retina [nTPM]":"4.0","Tissue RNA - salivary gland [nTPM]":"10.5","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"22.0","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"15.2","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"18.7","Tissue RNA - stomach 1 [nTPM]":"25.2","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"12.7","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"19.8","Tissue RNA - urinary bladder [nTPM]":"49.5","Tissue RNA - vagina [nTPM]":"15.0","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"8.2","Cell RNA - A549 [nTPM]":"6.6","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"19.2","Cell RNA - ASC TERT1 [nTPM]":"13.1","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"16.5","Cell RNA - BJ hTERT+ [nTPM]":"23.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.8","Cell RNA - CACO-2 [nTPM]":"8.2","Cell RNA - CAPAN-2 [nTPM]":"17.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"5.0","Cell RNA - fHDF\/TERT166 [nTPM]":"24.4","Cell RNA - GAMG [nTPM]":"29.7","Cell RNA - HaCaT [nTPM]":"21.8","Cell RNA - HAP1 [nTPM]":"1.6","Cell RNA - HBEC3-KT [nTPM]":"15.1","Cell RNA - HBF TERT88 [nTPM]":"19.7","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"3.6","Cell RNA - HEL [nTPM]":"4.8","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"7.3","Cell RNA - HHSteC [nTPM]":"35.5","Cell RNA - HL-60 [nTPM]":"8.1","Cell RNA - HMC-1 [nTPM]":"11.5","Cell RNA - HSkMC [nTPM]":"18.1","Cell RNA - hTCEpi [nTPM]":"71.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.8","Cell RNA - hTERT-HME1 [nTPM]":"73.8","Cell RNA - hTERT-RPE1 [nTPM]":"33.8","Cell RNA - HUVEC TERT2 [nTPM]":"25.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"34.3","Cell RNA - MCF7 [nTPM]":"4.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"12.6","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"61.2","Cell RNA - PC-3 [nTPM]":"10.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"23.5","Cell RNA - RT4 [nTPM]":"63.2","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"12.4","Cell RNA - SK-BR-3 [nTPM]":"13.0","Cell RNA - SK-MEL-30 [nTPM]":"12.5","Cell RNA - SuSa [nTPM]":"19.0","Cell RNA - T-47d [nTPM]":"9.4","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"4.3","Cell RNA - U-138 MG [nTPM]":"3.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"40.7","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"51.6","Cell RNA - U-937 [nTPM]":"30.6","Cell RNA - WM-115 [nTPM]":"51.9","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"5.6","Blood RNA - eosinophil [nTPM]":"4.2","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"6.9","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"5.4","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"78.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"150.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"76.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"15.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"75.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"67.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"104.2","Single Cell Type RNA - Bipolar cells [nTPM]":"37.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"84.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - dendritic cells [nTPM]":"13.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"6.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.4","Single Cell Type RNA - Endothelial cells [nTPM]":"78.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.8","Single Cell Type RNA - Fibroblasts [nTPM]":"57.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"78.8","Single Cell Type RNA - granulocytes [nTPM]":"133.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"52.1","Single Cell Type RNA - Hepatocytes [nTPM]":"48.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.4","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"88.4","Single Cell Type RNA - Langerhans cells [nTPM]":"262.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"107.1","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"70.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"40.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.3","Single Cell Type RNA - Paneth cells [nTPM]":"19.8","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"16.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"48.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"51.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"89.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.5","Single Cell Type RNA - T-cells [nTPM]":"54.7","Single Cell Type RNA - Theca cells [nTPM]":"3.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.3","Single Cell Type RNA - Urothelial cells [nTPM]":"116.1"},{"Gene":"AIFM1","Gene synonym":["AIF","AUNX1","CMTX4","DFNX5","NAMSD","PDCD8"],"Ensembl":"ENSG00000156709","Gene description":"Apoptosis inducing factor mitochondria associated 1","Uniprot":["O95831"],"Chromosome":"X","Position":"130124666-130165879","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["DNA-binding","Oxidoreductase"],"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Disease variant","Dwarfism","Mental retardation","Neurodegeneration","Neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"165.4","Proximal tubular cells":"326.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003764","HPA030611"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB003764":"AB_289587","HPA030611":"AB_2673549"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.42e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.0","Tissue RNA - adrenal gland [nTPM]":"65.2","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"17.6","Tissue RNA - basal ganglia [nTPM]":"11.2","Tissue RNA - bone marrow [nTPM]":"11.8","Tissue RNA - breast [nTPM]":"17.8","Tissue RNA - cerebellum [nTPM]":"11.9","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"15.7","Tissue RNA - choroid plexus [nTPM]":"24.7","Tissue RNA - colon [nTPM]":"34.3","Tissue RNA - duodenum [nTPM]":"52.9","Tissue RNA - endometrium 1 [nTPM]":"15.3","Tissue RNA - epididymis [nTPM]":"8.9","Tissue RNA - esophagus [nTPM]":"20.8","Tissue RNA - fallopian tube [nTPM]":"22.1","Tissue RNA - gallbladder [nTPM]":"10.1","Tissue RNA - heart muscle [nTPM]":"107.7","Tissue RNA - hippocampal formation [nTPM]":"10.9","Tissue RNA - hypothalamus [nTPM]":"11.6","Tissue RNA - kidney [nTPM]":"97.3","Tissue RNA - liver [nTPM]":"110.6","Tissue RNA - lung [nTPM]":"13.9","Tissue RNA - lymph node [nTPM]":"16.2","Tissue RNA - medulla oblongata [nTPM]":"11.3","Tissue RNA - midbrain [nTPM]":"11.0","Tissue RNA - ovary [nTPM]":"11.9","Tissue RNA - pancreas [nTPM]":"27.8","Tissue RNA - parathyroid gland [nTPM]":"29.7","Tissue RNA - pituitary gland [nTPM]":"16.2","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"14.8","Tissue RNA - rectum [nTPM]":"15.9","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"18.6","Tissue RNA - seminal vesicle [nTPM]":"7.6","Tissue RNA - skeletal muscle [nTPM]":"68.9","Tissue RNA - skin 1 [nTPM]":"15.2","Tissue RNA - small intestine [nTPM]":"29.9","Tissue RNA - smooth muscle [nTPM]":"10.1","Tissue RNA - spinal cord [nTPM]":"11.2","Tissue RNA - spleen [nTPM]":"20.3","Tissue RNA - stomach 1 [nTPM]":"41.2","Tissue RNA - testis [nTPM]":"30.3","Tissue RNA - thalamus [nTPM]":"12.1","Tissue RNA - thymus [nTPM]":"18.5","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"25.2","Tissue RNA - tonsil [nTPM]":"11.0","Tissue RNA - urinary bladder [nTPM]":"18.4","Tissue RNA - vagina [nTPM]":"13.4","Tissue RNA - white matter [nTPM]":"11.6","Cell RNA - A-431 [nTPM]":"52.8","Cell RNA - A549 [nTPM]":"95.4","Cell RNA - AF22 [nTPM]":"22.6","Cell RNA - AN3-CA [nTPM]":"85.2","Cell RNA - ASC diff [nTPM]":"24.1","Cell RNA - ASC TERT1 [nTPM]":"14.6","Cell RNA - BEWO [nTPM]":"50.0","Cell RNA - BJ [nTPM]":"28.6","Cell RNA - BJ hTERT+ [nTPM]":"19.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.2","Cell RNA - CACO-2 [nTPM]":"55.8","Cell RNA - CAPAN-2 [nTPM]":"36.4","Cell RNA - Daudi [nTPM]":"105.0","Cell RNA - EFO-21 [nTPM]":"113.3","Cell RNA - fHDF\/TERT166 [nTPM]":"17.5","Cell RNA - GAMG [nTPM]":"39.3","Cell RNA - HaCaT [nTPM]":"47.2","Cell RNA - HAP1 [nTPM]":"61.3","Cell RNA - HBEC3-KT [nTPM]":"33.3","Cell RNA - HBF TERT88 [nTPM]":"12.7","Cell RNA - HDLM-2 [nTPM]":"48.2","Cell RNA - HEK 293 [nTPM]":"73.4","Cell RNA - HEL [nTPM]":"61.6","Cell RNA - HeLa [nTPM]":"59.1","Cell RNA - Hep G2 [nTPM]":"68.9","Cell RNA - HHSteC [nTPM]":"34.0","Cell RNA - HL-60 [nTPM]":"51.5","Cell RNA - HMC-1 [nTPM]":"63.5","Cell RNA - HSkMC [nTPM]":"26.1","Cell RNA - hTCEpi [nTPM]":"21.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.5","Cell RNA - hTERT-HME1 [nTPM]":"22.0","Cell RNA - hTERT-RPE1 [nTPM]":"12.1","Cell RNA - HUVEC TERT2 [nTPM]":"27.2","Cell RNA - JURKAT [nTPM]":"83.4","Cell RNA - K-562 [nTPM]":"62.6","Cell RNA - Karpas-707 [nTPM]":"50.7","Cell RNA - LHCN-M2 [nTPM]":"13.1","Cell RNA - MCF7 [nTPM]":"96.7","Cell RNA - MOLT-4 [nTPM]":"57.6","Cell RNA - NB-4 [nTPM]":"74.5","Cell RNA - NTERA-2 [nTPM]":"24.4","Cell RNA - OE19 [nTPM]":"53.6","Cell RNA - PC-3 [nTPM]":"65.1","Cell RNA - REH [nTPM]":"55.6","Cell RNA - RH-30 [nTPM]":"31.7","Cell RNA - RPMI-8226 [nTPM]":"132.7","Cell RNA - RPTEC TERT1 [nTPM]":"60.8","Cell RNA - RT4 [nTPM]":"36.6","Cell RNA - SCLC-21H [nTPM]":"46.0","Cell RNA - SH-SY5Y [nTPM]":"28.2","Cell RNA - SiHa [nTPM]":"35.5","Cell RNA - SK-BR-3 [nTPM]":"68.0","Cell RNA - SK-MEL-30 [nTPM]":"67.5","Cell RNA - SuSa [nTPM]":"13.2","Cell RNA - T-47d [nTPM]":"46.0","Cell RNA - THP-1 [nTPM]":"40.8","Cell RNA - TIME [nTPM]":"31.7","Cell RNA - U-138 MG [nTPM]":"20.5","Cell RNA - U-2 OS [nTPM]":"20.4","Cell RNA - U-2197 [nTPM]":"63.9","Cell RNA - U-251 MG [nTPM]":"58.7","Cell RNA - U-266\/70 [nTPM]":"24.2","Cell RNA - U-266\/84 [nTPM]":"45.0","Cell RNA - U-698 [nTPM]":"47.5","Cell RNA - U-87 MG [nTPM]":"25.3","Cell RNA - U-937 [nTPM]":"86.4","Cell RNA - WM-115 [nTPM]":"33.4","Blood RNA - basophil [nTPM]":"4.1","Blood RNA - classical monocyte [nTPM]":"21.0","Blood RNA - eosinophil [nTPM]":"14.1","Blood RNA - gdT-cell [nTPM]":"11.8","Blood RNA - intermediate monocyte [nTPM]":"26.6","Blood RNA - MAIT T-cell [nTPM]":"13.1","Blood RNA - memory B-cell [nTPM]":"14.6","Blood RNA - memory CD4 T-cell [nTPM]":"12.8","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"31.7","Blood RNA - naive B-cell [nTPM]":"10.3","Blood RNA - naive CD4 T-cell [nTPM]":"12.7","Blood RNA - naive CD8 T-cell [nTPM]":"12.6","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"20.7","Blood RNA - non-classical monocyte [nTPM]":"24.8","Blood RNA - plasmacytoid DC [nTPM]":"14.7","Blood RNA - T-reg [nTPM]":"17.9","Blood RNA - total PBMC [nTPM]":"12.4","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"11.2","Brain RNA - cerebellum [nTPM]":"11.9","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"10.9","Brain RNA - hypothalamus [nTPM]":"11.6","Brain RNA - medulla oblongata [nTPM]":"11.3","Brain RNA - midbrain [nTPM]":"11.0","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"11.2","Brain RNA - thalamus [nTPM]":"12.1","Brain RNA - white matter [nTPM]":"11.6","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.1","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"17.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"19.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"165.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"21.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"58.0","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"92.0","Single Cell Type RNA - Ductal cells [nTPM]":"24.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.3","Single Cell Type RNA - Endothelial cells [nTPM]":"11.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"26.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.0","Single Cell Type RNA - Fibroblasts [nTPM]":"16.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"50.4","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"33.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"92.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.0","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.0","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"14.4","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"16.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"16.6","Single Cell Type RNA - Muller glia cells [nTPM]":"17.2","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.0","Single Cell Type RNA - Paneth cells [nTPM]":"18.9","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"19.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"326.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"39.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.2","Single Cell Type RNA - Spermatogonia [nTPM]":"32.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.7","Single Cell Type RNA - T-cells [nTPM]":"15.8","Single Cell Type RNA - Theca cells [nTPM]":"45.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"37.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.8"},{"Gene":"AIPL1","Gene synonym":["LCA4"],"Ensembl":"ENSG00000129221","Gene description":"Aryl hydrocarbon receptor interacting protein like 1","Uniprot":["Q9NZN9"],"Chromosome":"17","Position":"6393693-6435199","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"1012","RNA tissue specific nTPM":{"retina":"836.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"1926.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"testis cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"1.5","OE19":"2.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026578"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA026578":"AB_2671905"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"836.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"2.8","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"139.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"412.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"7.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"8.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"65.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"256.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1926.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"ALDH18A1","Gene synonym":["GSAS","P5CS","PYCS","SPG9"],"Ensembl":"ENSG00000059573","Gene description":"Aldehyde dehydrogenase 18 family member A1","Uniprot":["P54886"],"Chromosome":"10","Position":"95605941-95656711","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Proline biosynthesis"],"Molecular function":["Kinase","Multifunctional enzyme","Oxidoreductase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"120.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"80.5","Granulosa cells":"81.6","Proximal enterocytes":"79.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008333","HPA012604"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"48000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA008333":"AB_1078125","HPA012604":"AB_1844721"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.20e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.60e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.3","Tissue RNA - adrenal gland [nTPM]":"16.1","Tissue RNA - amygdala [nTPM]":"12.2","Tissue RNA - appendix [nTPM]":"21.2","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"16.7","Tissue RNA - breast [nTPM]":"20.2","Tissue RNA - cerebellum [nTPM]":"12.4","Tissue RNA - cerebral cortex [nTPM]":"13.1","Tissue RNA - cervix [nTPM]":"33.4","Tissue RNA - choroid plexus [nTPM]":"21.0","Tissue RNA - colon [nTPM]":"51.9","Tissue RNA - duodenum [nTPM]":"89.3","Tissue RNA - endometrium 1 [nTPM]":"18.5","Tissue RNA - epididymis [nTPM]":"30.9","Tissue RNA - esophagus [nTPM]":"21.0","Tissue RNA - fallopian tube [nTPM]":"21.9","Tissue RNA - gallbladder [nTPM]":"25.2","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"12.2","Tissue RNA - hypothalamus [nTPM]":"13.6","Tissue RNA - kidney [nTPM]":"17.7","Tissue RNA - liver [nTPM]":"24.3","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"22.0","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"14.7","Tissue RNA - ovary [nTPM]":"16.7","Tissue RNA - pancreas [nTPM]":"61.8","Tissue RNA - parathyroid gland [nTPM]":"33.5","Tissue RNA - pituitary gland [nTPM]":"28.2","Tissue RNA - placenta [nTPM]":"26.3","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"24.2","Tissue RNA - rectum [nTPM]":"49.3","Tissue RNA - retina [nTPM]":"11.4","Tissue RNA - salivary gland [nTPM]":"120.1","Tissue RNA - seminal vesicle [nTPM]":"24.9","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"22.4","Tissue RNA - small intestine [nTPM]":"73.1","Tissue RNA - smooth muscle [nTPM]":"26.3","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"12.1","Tissue RNA - stomach 1 [nTPM]":"40.5","Tissue RNA - testis [nTPM]":"11.7","Tissue RNA - thalamus [nTPM]":"14.0","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"37.5","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"26.9","Tissue RNA - urinary bladder [nTPM]":"25.2","Tissue RNA - vagina [nTPM]":"14.3","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"66.5","Cell RNA - A549 [nTPM]":"61.6","Cell RNA - AF22 [nTPM]":"57.9","Cell RNA - AN3-CA [nTPM]":"152.7","Cell RNA - ASC diff [nTPM]":"76.0","Cell RNA - ASC TERT1 [nTPM]":"72.9","Cell RNA - BEWO [nTPM]":"62.2","Cell RNA - BJ [nTPM]":"75.6","Cell RNA - BJ hTERT+ [nTPM]":"112.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"75.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"93.7","Cell RNA - CACO-2 [nTPM]":"124.4","Cell RNA - CAPAN-2 [nTPM]":"51.6","Cell RNA - Daudi [nTPM]":"223.7","Cell RNA - EFO-21 [nTPM]":"68.9","Cell RNA - fHDF\/TERT166 [nTPM]":"119.7","Cell RNA - GAMG [nTPM]":"36.2","Cell RNA - HaCaT [nTPM]":"85.6","Cell RNA - HAP1 [nTPM]":"117.1","Cell RNA - HBEC3-KT [nTPM]":"77.8","Cell RNA - HBF TERT88 [nTPM]":"84.6","Cell RNA - HDLM-2 [nTPM]":"64.0","Cell RNA - HEK 293 [nTPM]":"92.0","Cell RNA - HEL [nTPM]":"71.2","Cell RNA - HeLa [nTPM]":"40.5","Cell RNA - Hep G2 [nTPM]":"177.9","Cell RNA - HHSteC [nTPM]":"49.7","Cell RNA - HL-60 [nTPM]":"125.6","Cell RNA - HMC-1 [nTPM]":"76.1","Cell RNA - HSkMC [nTPM]":"77.0","Cell RNA - hTCEpi [nTPM]":"46.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"61.5","Cell RNA - hTERT-HME1 [nTPM]":"119.1","Cell RNA - hTERT-RPE1 [nTPM]":"124.5","Cell RNA - HUVEC TERT2 [nTPM]":"79.9","Cell RNA - JURKAT [nTPM]":"82.6","Cell RNA - K-562 [nTPM]":"67.5","Cell RNA - Karpas-707 [nTPM]":"46.0","Cell RNA - LHCN-M2 [nTPM]":"57.1","Cell RNA - MCF7 [nTPM]":"95.0","Cell RNA - MOLT-4 [nTPM]":"114.5","Cell RNA - NB-4 [nTPM]":"80.5","Cell RNA - NTERA-2 [nTPM]":"68.6","Cell RNA - OE19 [nTPM]":"109.2","Cell RNA - PC-3 [nTPM]":"60.7","Cell RNA - REH [nTPM]":"105.9","Cell RNA - RH-30 [nTPM]":"66.3","Cell RNA - RPMI-8226 [nTPM]":"76.9","Cell RNA - RPTEC TERT1 [nTPM]":"88.3","Cell RNA - RT4 [nTPM]":"49.7","Cell RNA - SCLC-21H [nTPM]":"57.5","Cell RNA - SH-SY5Y [nTPM]":"56.9","Cell RNA - SiHa [nTPM]":"60.1","Cell RNA - SK-BR-3 [nTPM]":"47.1","Cell RNA - SK-MEL-30 [nTPM]":"56.9","Cell RNA - SuSa [nTPM]":"66.0","Cell RNA - T-47d [nTPM]":"70.5","Cell RNA - THP-1 [nTPM]":"57.9","Cell RNA - TIME [nTPM]":"66.7","Cell RNA - U-138 MG [nTPM]":"31.1","Cell RNA - U-2 OS [nTPM]":"49.0","Cell RNA - U-2197 [nTPM]":"80.9","Cell RNA - U-251 MG [nTPM]":"88.2","Cell RNA - U-266\/70 [nTPM]":"52.4","Cell RNA - U-266\/84 [nTPM]":"41.7","Cell RNA - U-698 [nTPM]":"135.8","Cell RNA - U-87 MG [nTPM]":"60.4","Cell RNA - U-937 [nTPM]":"142.8","Cell RNA - WM-115 [nTPM]":"40.7","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"27.3","Blood RNA - intermediate monocyte [nTPM]":"5.2","Blood RNA - MAIT T-cell [nTPM]":"28.7","Blood RNA - memory B-cell [nTPM]":"23.0","Blood RNA - memory CD4 T-cell [nTPM]":"24.5","Blood RNA - memory CD8 T-cell [nTPM]":"28.3","Blood RNA - myeloid DC [nTPM]":"9.6","Blood RNA - naive B-cell [nTPM]":"16.1","Blood RNA - naive CD4 T-cell [nTPM]":"20.7","Blood RNA - naive CD8 T-cell [nTPM]":"23.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"26.3","Blood RNA - non-classical monocyte [nTPM]":"8.3","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"25.8","Blood RNA - total PBMC [nTPM]":"15.5","Brain RNA - amygdala [nTPM]":"12.2","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"12.4","Brain RNA - cerebral cortex [nTPM]":"13.1","Brain RNA - hippocampal formation [nTPM]":"12.2","Brain RNA - hypothalamus [nTPM]":"13.6","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"14.7","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"14.0","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"12.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"14.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"80.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.1","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"17.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.6","Single Cell Type RNA - Fibroblasts [nTPM]":"16.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.9","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"81.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"27.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.5","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"3.5","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"2.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"56.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"30.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"79.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.2","Single Cell Type RNA - Spermatogonia [nTPM]":"9.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.2","Single Cell Type RNA - T-cells [nTPM]":"9.0","Single Cell Type RNA - Theca cells [nTPM]":"10.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"38.7","Single Cell Type RNA - Urothelial cells [nTPM]":"9.4"},{"Gene":"ALDH7A1","Gene synonym":["ATQ1","EPD","PDE"],"Ensembl":"ENSG00000164904","Gene description":"Aldehyde dehydrogenase 7 family member A1","Uniprot":["P49419"],"Chromosome":"5","Position":"126531200-126595362","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"162.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"414.1","Proximal tubular cells":"302.1","Syncytiotrophoblasts":"222.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"6.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"6.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"256.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023296","HPA053675"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"430000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA023296":"AB_1844738","HPA053675":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.7","Tissue RNA - adrenal gland [nTPM]":"38.3","Tissue RNA - amygdala [nTPM]":"46.6","Tissue RNA - appendix [nTPM]":"9.1","Tissue RNA - basal ganglia [nTPM]":"47.6","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"47.1","Tissue RNA - cerebellum [nTPM]":"43.7","Tissue RNA - cerebral cortex [nTPM]":"45.8","Tissue RNA - cervix [nTPM]":"32.7","Tissue RNA - choroid plexus [nTPM]":"40.7","Tissue RNA - colon [nTPM]":"29.5","Tissue RNA - duodenum [nTPM]":"23.7","Tissue RNA - endometrium 1 [nTPM]":"25.1","Tissue RNA - epididymis [nTPM]":"8.8","Tissue RNA - esophagus [nTPM]":"35.9","Tissue RNA - fallopian tube [nTPM]":"28.8","Tissue RNA - gallbladder [nTPM]":"19.1","Tissue RNA - heart muscle [nTPM]":"27.9","Tissue RNA - hippocampal formation [nTPM]":"44.7","Tissue RNA - hypothalamus [nTPM]":"43.2","Tissue RNA - kidney [nTPM]":"115.1","Tissue RNA - liver [nTPM]":"162.2","Tissue RNA - lung [nTPM]":"15.7","Tissue RNA - lymph node [nTPM]":"8.6","Tissue RNA - medulla oblongata [nTPM]":"43.1","Tissue RNA - midbrain [nTPM]":"43.5","Tissue RNA - ovary [nTPM]":"65.3","Tissue RNA - pancreas [nTPM]":"27.0","Tissue RNA - parathyroid gland [nTPM]":"34.0","Tissue RNA - pituitary gland [nTPM]":"8.8","Tissue RNA - placenta [nTPM]":"44.9","Tissue RNA - pons [nTPM]":"42.6","Tissue RNA - prostate [nTPM]":"42.0","Tissue RNA - rectum [nTPM]":"27.4","Tissue RNA - retina [nTPM]":"19.7","Tissue RNA - salivary gland [nTPM]":"40.6","Tissue RNA - seminal vesicle [nTPM]":"27.9","Tissue RNA - skeletal muscle [nTPM]":"12.2","Tissue RNA - skin 1 [nTPM]":"29.4","Tissue RNA - small intestine [nTPM]":"21.0","Tissue RNA - smooth muscle [nTPM]":"23.6","Tissue RNA - spinal cord [nTPM]":"44.8","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"23.6","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"44.0","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"47.6","Tissue RNA - tongue [nTPM]":"26.5","Tissue RNA - tonsil [nTPM]":"17.1","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"20.9","Tissue RNA - white matter [nTPM]":"45.2","Cell RNA - A-431 [nTPM]":"64.9","Cell RNA - A549 [nTPM]":"41.9","Cell RNA - AF22 [nTPM]":"116.6","Cell RNA - AN3-CA [nTPM]":"193.4","Cell RNA - ASC diff [nTPM]":"95.5","Cell RNA - ASC TERT1 [nTPM]":"56.4","Cell RNA - BEWO [nTPM]":"147.8","Cell RNA - BJ [nTPM]":"76.1","Cell RNA - BJ hTERT+ [nTPM]":"93.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"86.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"110.5","Cell RNA - CACO-2 [nTPM]":"118.6","Cell RNA - CAPAN-2 [nTPM]":"60.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"75.5","Cell RNA - fHDF\/TERT166 [nTPM]":"60.0","Cell RNA - GAMG [nTPM]":"36.1","Cell RNA - HaCaT [nTPM]":"47.1","Cell RNA - HAP1 [nTPM]":"36.5","Cell RNA - HBEC3-KT [nTPM]":"256.2","Cell RNA - HBF TERT88 [nTPM]":"78.8","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"44.6","Cell RNA - HEL [nTPM]":"12.3","Cell RNA - HeLa [nTPM]":"63.1","Cell RNA - Hep G2 [nTPM]":"102.1","Cell RNA - HHSteC [nTPM]":"46.3","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"69.0","Cell RNA - hTCEpi [nTPM]":"59.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"67.3","Cell RNA - hTERT-HME1 [nTPM]":"47.7","Cell RNA - hTERT-RPE1 [nTPM]":"64.2","Cell RNA - HUVEC TERT2 [nTPM]":"70.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"77.1","Cell RNA - MCF7 [nTPM]":"42.1","Cell RNA - MOLT-4 [nTPM]":"2.6","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"79.4","Cell RNA - OE19 [nTPM]":"47.5","Cell RNA - PC-3 [nTPM]":"35.2","Cell RNA - REH [nTPM]":"38.9","Cell RNA - RH-30 [nTPM]":"131.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"81.2","Cell RNA - RT4 [nTPM]":"48.4","Cell RNA - SCLC-21H [nTPM]":"39.4","Cell RNA - SH-SY5Y [nTPM]":"47.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"41.1","Cell RNA - SK-MEL-30 [nTPM]":"44.7","Cell RNA - SuSa [nTPM]":"89.0","Cell RNA - T-47d [nTPM]":"75.2","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"86.1","Cell RNA - U-138 MG [nTPM]":"24.8","Cell RNA - U-2 OS [nTPM]":"75.6","Cell RNA - U-2197 [nTPM]":"28.8","Cell RNA - U-251 MG [nTPM]":"53.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"13.4","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"40.6","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"6.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"46.6","Brain RNA - basal ganglia [nTPM]":"47.6","Brain RNA - cerebellum [nTPM]":"43.7","Brain RNA - cerebral cortex [nTPM]":"45.8","Brain RNA - hippocampal formation [nTPM]":"44.7","Brain RNA - hypothalamus [nTPM]":"43.2","Brain RNA - medulla oblongata [nTPM]":"43.1","Brain RNA - midbrain [nTPM]":"43.5","Brain RNA - pons [nTPM]":"42.6","Brain RNA - spinal cord [nTPM]":"44.8","Brain RNA - thalamus [nTPM]":"44.0","Brain RNA - white matter [nTPM]":"45.2","Single Cell Type RNA - Adipocytes [nTPM]":"17.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"99.3","Single Cell Type RNA - B-cells [nTPM]":"5.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"110.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"87.0","Single Cell Type RNA - Bipolar cells [nTPM]":"23.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"91.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"43.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"414.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"76.3","Single Cell Type RNA - Ductal cells [nTPM]":"43.5","Single Cell Type RNA - Early spermatids [nTPM]":"31.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.3","Single Cell Type RNA - Endothelial cells [nTPM]":"19.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"107.8","Single Cell Type RNA - Fibroblasts [nTPM]":"34.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.4","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"50.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"74.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"41.7","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"7.5","Single Cell Type RNA - Muller glia cells [nTPM]":"102.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.6","Single Cell Type RNA - Paneth cells [nTPM]":"15.6","Single Cell Type RNA - Peritubular cells [nTPM]":"37.2","Single Cell Type RNA - Plasma cells [nTPM]":"2.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"302.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"59.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"222.3","Single Cell Type RNA - T-cells [nTPM]":"4.6","Single Cell Type RNA - Theca cells [nTPM]":"39.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.4","Single Cell Type RNA - Urothelial cells [nTPM]":"50.4"},{"Gene":"ALG13","Gene synonym":["CDG1S","CXorf45","FLJ23018","GLT28D1","MDS031","TDRD13","YGL047W"],"Ensembl":"ENSG00000101901","Gene description":"ALG13 UDP-N-acetylglucosaminyltransferase subunit","Uniprot":["Q9NP73"],"Chromosome":"X","Position":"111665811-111760649","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Glycosyltransferase","Hydrolase","Multifunctional enzyme","Protease","Thiol protease","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002853","HPA005498"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA002853":"AB_1078131","HPA005498":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.10e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.1","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"18.8","Tissue RNA - basal ganglia [nTPM]":"11.7","Tissue RNA - bone marrow [nTPM]":"16.6","Tissue RNA - breast [nTPM]":"18.3","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"19.0","Tissue RNA - cervix [nTPM]":"17.2","Tissue RNA - choroid plexus [nTPM]":"12.3","Tissue RNA - colon [nTPM]":"18.2","Tissue RNA - duodenum [nTPM]":"13.7","Tissue RNA - endometrium 1 [nTPM]":"16.1","Tissue RNA - epididymis [nTPM]":"20.5","Tissue RNA - esophagus [nTPM]":"14.7","Tissue RNA - fallopian tube [nTPM]":"15.4","Tissue RNA - gallbladder [nTPM]":"16.4","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"13.8","Tissue RNA - kidney [nTPM]":"21.0","Tissue RNA - liver [nTPM]":"23.8","Tissue RNA - lung [nTPM]":"13.8","Tissue RNA - lymph node [nTPM]":"23.4","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"12.1","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"14.7","Tissue RNA - parathyroid gland [nTPM]":"23.4","Tissue RNA - pituitary gland [nTPM]":"17.9","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"13.3","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"19.4","Tissue RNA - retina [nTPM]":"11.8","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"13.4","Tissue RNA - skeletal muscle [nTPM]":"9.2","Tissue RNA - skin 1 [nTPM]":"19.4","Tissue RNA - small intestine [nTPM]":"17.3","Tissue RNA - smooth muscle [nTPM]":"17.5","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"18.5","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"17.4","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"18.2","Tissue RNA - tongue [nTPM]":"9.9","Tissue RNA - tonsil [nTPM]":"20.1","Tissue RNA - urinary bladder [nTPM]":"21.3","Tissue RNA - vagina [nTPM]":"14.7","Tissue RNA - white matter [nTPM]":"16.6","Cell RNA - A-431 [nTPM]":"22.3","Cell RNA - A549 [nTPM]":"24.4","Cell RNA - AF22 [nTPM]":"21.8","Cell RNA - AN3-CA [nTPM]":"13.8","Cell RNA - ASC diff [nTPM]":"13.8","Cell RNA - ASC TERT1 [nTPM]":"19.6","Cell RNA - BEWO [nTPM]":"12.3","Cell RNA - BJ [nTPM]":"17.7","Cell RNA - BJ hTERT+ [nTPM]":"18.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.5","Cell RNA - CACO-2 [nTPM]":"24.9","Cell RNA - CAPAN-2 [nTPM]":"23.1","Cell RNA - Daudi [nTPM]":"19.5","Cell RNA - EFO-21 [nTPM]":"33.0","Cell RNA - fHDF\/TERT166 [nTPM]":"24.7","Cell RNA - GAMG [nTPM]":"46.5","Cell RNA - HaCaT [nTPM]":"12.6","Cell RNA - HAP1 [nTPM]":"26.1","Cell RNA - HBEC3-KT [nTPM]":"12.5","Cell RNA - HBF TERT88 [nTPM]":"23.5","Cell RNA - HDLM-2 [nTPM]":"14.4","Cell RNA - HEK 293 [nTPM]":"17.6","Cell RNA - HEL [nTPM]":"10.7","Cell RNA - HeLa [nTPM]":"26.1","Cell RNA - Hep G2 [nTPM]":"28.4","Cell RNA - HHSteC [nTPM]":"20.3","Cell RNA - HL-60 [nTPM]":"19.5","Cell RNA - HMC-1 [nTPM]":"40.5","Cell RNA - HSkMC [nTPM]":"23.6","Cell RNA - hTCEpi [nTPM]":"22.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.0","Cell RNA - hTERT-HME1 [nTPM]":"38.6","Cell RNA - hTERT-RPE1 [nTPM]":"23.3","Cell RNA - HUVEC TERT2 [nTPM]":"24.8","Cell RNA - JURKAT [nTPM]":"21.8","Cell RNA - K-562 [nTPM]":"23.9","Cell RNA - Karpas-707 [nTPM]":"53.5","Cell RNA - LHCN-M2 [nTPM]":"22.5","Cell RNA - MCF7 [nTPM]":"55.8","Cell RNA - MOLT-4 [nTPM]":"16.4","Cell RNA - NB-4 [nTPM]":"17.6","Cell RNA - NTERA-2 [nTPM]":"19.9","Cell RNA - OE19 [nTPM]":"66.3","Cell RNA - PC-3 [nTPM]":"33.6","Cell RNA - REH [nTPM]":"12.8","Cell RNA - RH-30 [nTPM]":"13.9","Cell RNA - RPMI-8226 [nTPM]":"26.7","Cell RNA - RPTEC TERT1 [nTPM]":"36.6","Cell RNA - RT4 [nTPM]":"34.0","Cell RNA - SCLC-21H [nTPM]":"13.1","Cell RNA - SH-SY5Y [nTPM]":"19.1","Cell RNA - SiHa [nTPM]":"25.2","Cell RNA - SK-BR-3 [nTPM]":"15.2","Cell RNA - SK-MEL-30 [nTPM]":"16.3","Cell RNA - SuSa [nTPM]":"21.7","Cell RNA - T-47d [nTPM]":"13.6","Cell RNA - THP-1 [nTPM]":"18.5","Cell RNA - TIME [nTPM]":"16.7","Cell RNA - U-138 MG [nTPM]":"19.2","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"24.9","Cell RNA - U-251 MG [nTPM]":"34.4","Cell RNA - U-266\/70 [nTPM]":"25.8","Cell RNA - U-266\/84 [nTPM]":"47.1","Cell RNA - U-698 [nTPM]":"31.5","Cell RNA - U-87 MG [nTPM]":"20.5","Cell RNA - U-937 [nTPM]":"25.5","Cell RNA - WM-115 [nTPM]":"15.2","Blood RNA - basophil [nTPM]":"39.5","Blood RNA - classical monocyte [nTPM]":"15.8","Blood RNA - eosinophil [nTPM]":"16.6","Blood RNA - gdT-cell [nTPM]":"9.5","Blood RNA - intermediate monocyte [nTPM]":"16.3","Blood RNA - MAIT T-cell [nTPM]":"9.3","Blood RNA - memory B-cell [nTPM]":"10.6","Blood RNA - memory CD4 T-cell [nTPM]":"10.6","Blood RNA - memory CD8 T-cell [nTPM]":"9.2","Blood RNA - myeloid DC [nTPM]":"18.5","Blood RNA - naive B-cell [nTPM]":"12.1","Blood RNA - naive CD4 T-cell [nTPM]":"13.0","Blood RNA - naive CD8 T-cell [nTPM]":"10.8","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"4.6","Blood RNA - non-classical monocyte [nTPM]":"12.9","Blood RNA - plasmacytoid DC [nTPM]":"9.5","Blood RNA - T-reg [nTPM]":"14.6","Blood RNA - total PBMC [nTPM]":"9.6","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"11.7","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"19.0","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"13.8","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"12.1","Brain RNA - pons [nTPM]":"13.3","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"16.6","Single Cell Type RNA - Adipocytes [nTPM]":"50.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.8","Single Cell Type RNA - Astrocytes [nTPM]":"33.6","Single Cell Type RNA - B-cells [nTPM]":"127.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"65.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"36.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.3","Single Cell Type RNA - dendritic cells [nTPM]":"73.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Ductal cells [nTPM]":"37.4","Single Cell Type RNA - Early spermatids [nTPM]":"21.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.1","Single Cell Type RNA - Endothelial cells [nTPM]":"37.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.5","Single Cell Type RNA - Erythroid cells [nTPM]":"27.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"64.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.1","Single Cell Type RNA - Fibroblasts [nTPM]":"34.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.9","Single Cell Type RNA - granulocytes [nTPM]":"109.8","Single Cell Type RNA - Granulosa cells [nTPM]":"15.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"28.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.5","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"57.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.0","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"39.2","Single Cell Type RNA - Langerhans cells [nTPM]":"52.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.4","Single Cell Type RNA - Leydig cells [nTPM]":"21.5","Single Cell Type RNA - Macrophages [nTPM]":"56.1","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"83.4","Single Cell Type RNA - monocytes [nTPM]":"41.8","Single Cell Type RNA - Muller glia cells [nTPM]":"16.0","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"77.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.0","Single Cell Type RNA - Paneth cells [nTPM]":"55.6","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"60.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"55.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.2","Single Cell Type RNA - Spermatocytes [nTPM]":"32.6","Single Cell Type RNA - Spermatogonia [nTPM]":"22.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.7","Single Cell Type RNA - T-cells [nTPM]":"71.1","Single Cell Type RNA - Theca cells [nTPM]":"28.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.8","Single Cell Type RNA - Urothelial cells [nTPM]":"64.6"},{"Gene":"ALG14","Gene synonym":["MGC19780"],"Ensembl":"ENSG00000172339","Gene description":"ALG14 UDP-N-acetylglucosaminyltransferase subunit","Uniprot":["Q96F25"],"Chromosome":"1","Position":"94974405-95072951","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031829"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA031829":"AB_2674062"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"1.5","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"2.5","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"1.2","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"1.7","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"1.8","Cell RNA - BJ hTERT+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.5","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"1.3","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"2.2","Cell RNA - GAMG [nTPM]":"2.2","Cell RNA - HaCaT [nTPM]":"1.7","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"1.7","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"2.8","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"1.6","Cell RNA - Hep G2 [nTPM]":"2.9","Cell RNA - HHSteC [nTPM]":"1.6","Cell RNA - HL-60 [nTPM]":"1.7","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"1.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.4","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.6","Cell RNA - JURKAT [nTPM]":"1.7","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"1.6","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"2.5","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"1.4","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"3.4","Cell RNA - SK-MEL-30 [nTPM]":"3.2","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"3.9","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"11.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.2","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"13.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"16.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"20.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.6","Single Cell Type RNA - dendritic cells [nTPM]":"10.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"24.9","Single Cell Type RNA - Early spermatids [nTPM]":"10.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.6","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"13.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"53.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.9","Single Cell Type RNA - Fibroblasts [nTPM]":"18.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"32.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"8.4","Single Cell Type RNA - Langerhans cells [nTPM]":"8.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.4","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"8.6","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"30.9","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.6","Single Cell Type RNA - Paneth cells [nTPM]":"22.6","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"41.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.2","Single Cell Type RNA - Spermatocytes [nTPM]":"36.1","Single Cell Type RNA - Spermatogonia [nTPM]":"23.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"39.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.9","Single Cell Type RNA - Urothelial cells [nTPM]":"12.9"},{"Gene":"ALG2","Gene synonym":["CDG1I","CDGIi","FLJ14511","hALPG2","NET38"],"Ensembl":"ENSG00000119523","Gene description":"ALG2 alpha-1,3\/1,6-mannosyltransferase","Uniprot":["Q9H553"],"Chromosome":"9","Position":"99216425-99221942","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041512","HPA041601"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA041512":"AB_10794380","HPA041601":"AB_10794302"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.44e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.56e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.7","Tissue RNA - adrenal gland [nTPM]":"38.2","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"19.4","Tissue RNA - basal ganglia [nTPM]":"14.6","Tissue RNA - bone marrow [nTPM]":"23.0","Tissue RNA - breast [nTPM]":"27.1","Tissue RNA - cerebellum [nTPM]":"16.6","Tissue RNA - cerebral cortex [nTPM]":"18.4","Tissue RNA - cervix [nTPM]":"35.1","Tissue RNA - choroid plexus [nTPM]":"19.8","Tissue RNA - colon [nTPM]":"24.9","Tissue RNA - duodenum [nTPM]":"21.9","Tissue RNA - endometrium 1 [nTPM]":"23.8","Tissue RNA - epididymis [nTPM]":"74.0","Tissue RNA - esophagus [nTPM]":"15.1","Tissue RNA - fallopian tube [nTPM]":"29.5","Tissue RNA - gallbladder [nTPM]":"26.2","Tissue RNA - heart muscle [nTPM]":"13.4","Tissue RNA - hippocampal formation [nTPM]":"14.5","Tissue RNA - hypothalamus [nTPM]":"15.0","Tissue RNA - kidney [nTPM]":"34.3","Tissue RNA - liver [nTPM]":"47.4","Tissue RNA - lung [nTPM]":"24.3","Tissue RNA - lymph node [nTPM]":"20.8","Tissue RNA - medulla oblongata [nTPM]":"14.7","Tissue RNA - midbrain [nTPM]":"16.1","Tissue RNA - ovary [nTPM]":"30.2","Tissue RNA - pancreas [nTPM]":"42.0","Tissue RNA - parathyroid gland [nTPM]":"37.0","Tissue RNA - pituitary gland [nTPM]":"21.8","Tissue RNA - placenta [nTPM]":"29.9","Tissue RNA - pons [nTPM]":"15.1","Tissue RNA - prostate [nTPM]":"32.8","Tissue RNA - rectum [nTPM]":"27.3","Tissue RNA - retina [nTPM]":"15.0","Tissue RNA - salivary gland [nTPM]":"37.9","Tissue RNA - seminal vesicle [nTPM]":"34.5","Tissue RNA - skeletal muscle [nTPM]":"15.3","Tissue RNA - skin 1 [nTPM]":"17.9","Tissue RNA - small intestine [nTPM]":"20.5","Tissue RNA - smooth muscle [nTPM]":"24.2","Tissue RNA - spinal cord [nTPM]":"14.8","Tissue RNA - spleen [nTPM]":"17.9","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"19.2","Tissue RNA - thalamus [nTPM]":"14.7","Tissue RNA - thymus [nTPM]":"16.7","Tissue RNA - thyroid gland [nTPM]":"42.3","Tissue RNA - tongue [nTPM]":"13.5","Tissue RNA - tonsil [nTPM]":"27.5","Tissue RNA - urinary bladder [nTPM]":"31.7","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"16.9","Cell RNA - A-431 [nTPM]":"22.9","Cell RNA - A549 [nTPM]":"28.7","Cell RNA - AF22 [nTPM]":"22.7","Cell RNA - AN3-CA [nTPM]":"34.4","Cell RNA - ASC diff [nTPM]":"82.6","Cell RNA - ASC TERT1 [nTPM]":"52.7","Cell RNA - BEWO [nTPM]":"42.0","Cell RNA - BJ [nTPM]":"46.7","Cell RNA - BJ hTERT+ [nTPM]":"75.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.3","Cell RNA - CACO-2 [nTPM]":"34.9","Cell RNA - CAPAN-2 [nTPM]":"31.2","Cell RNA - Daudi [nTPM]":"24.6","Cell RNA - EFO-21 [nTPM]":"18.8","Cell RNA - fHDF\/TERT166 [nTPM]":"54.3","Cell RNA - GAMG [nTPM]":"60.0","Cell RNA - HaCaT [nTPM]":"85.3","Cell RNA - HAP1 [nTPM]":"37.9","Cell RNA - HBEC3-KT [nTPM]":"49.1","Cell RNA - HBF TERT88 [nTPM]":"45.7","Cell RNA - HDLM-2 [nTPM]":"35.2","Cell RNA - HEK 293 [nTPM]":"16.2","Cell RNA - HEL [nTPM]":"14.4","Cell RNA - HeLa [nTPM]":"23.7","Cell RNA - Hep G2 [nTPM]":"54.0","Cell RNA - HHSteC [nTPM]":"99.7","Cell RNA - HL-60 [nTPM]":"28.2","Cell RNA - HMC-1 [nTPM]":"26.2","Cell RNA - HSkMC [nTPM]":"61.9","Cell RNA - hTCEpi [nTPM]":"65.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.7","Cell RNA - hTERT-HME1 [nTPM]":"72.8","Cell RNA - hTERT-RPE1 [nTPM]":"45.8","Cell RNA - HUVEC TERT2 [nTPM]":"52.3","Cell RNA - JURKAT [nTPM]":"15.1","Cell RNA - K-562 [nTPM]":"23.2","Cell RNA - Karpas-707 [nTPM]":"56.2","Cell RNA - LHCN-M2 [nTPM]":"44.7","Cell RNA - MCF7 [nTPM]":"47.8","Cell RNA - MOLT-4 [nTPM]":"12.9","Cell RNA - NB-4 [nTPM]":"29.8","Cell RNA - NTERA-2 [nTPM]":"27.6","Cell RNA - OE19 [nTPM]":"75.0","Cell RNA - PC-3 [nTPM]":"39.6","Cell RNA - REH [nTPM]":"14.0","Cell RNA - RH-30 [nTPM]":"43.4","Cell RNA - RPMI-8226 [nTPM]":"38.1","Cell RNA - RPTEC TERT1 [nTPM]":"65.2","Cell RNA - RT4 [nTPM]":"31.1","Cell RNA - SCLC-21H [nTPM]":"22.5","Cell RNA - SH-SY5Y [nTPM]":"19.3","Cell RNA - SiHa [nTPM]":"33.5","Cell RNA - SK-BR-3 [nTPM]":"63.8","Cell RNA - SK-MEL-30 [nTPM]":"61.6","Cell RNA - SuSa [nTPM]":"33.5","Cell RNA - T-47d [nTPM]":"24.4","Cell RNA - THP-1 [nTPM]":"23.3","Cell RNA - TIME [nTPM]":"38.8","Cell RNA - U-138 MG [nTPM]":"31.4","Cell RNA - U-2 OS [nTPM]":"27.9","Cell RNA - U-2197 [nTPM]":"40.9","Cell RNA - U-251 MG [nTPM]":"28.6","Cell RNA - U-266\/70 [nTPM]":"45.8","Cell RNA - U-266\/84 [nTPM]":"28.0","Cell RNA - U-698 [nTPM]":"10.5","Cell RNA - U-87 MG [nTPM]":"58.6","Cell RNA - U-937 [nTPM]":"20.5","Cell RNA - WM-115 [nTPM]":"16.3","Blood RNA - basophil [nTPM]":"38.7","Blood RNA - classical monocyte [nTPM]":"35.5","Blood RNA - eosinophil [nTPM]":"22.0","Blood RNA - gdT-cell [nTPM]":"33.7","Blood RNA - intermediate monocyte [nTPM]":"28.2","Blood RNA - MAIT T-cell [nTPM]":"49.2","Blood RNA - memory B-cell [nTPM]":"30.8","Blood RNA - memory CD4 T-cell [nTPM]":"32.0","Blood RNA - memory CD8 T-cell [nTPM]":"33.9","Blood RNA - myeloid DC [nTPM]":"45.1","Blood RNA - naive B-cell [nTPM]":"26.3","Blood RNA - naive CD4 T-cell [nTPM]":"27.7","Blood RNA - naive CD8 T-cell [nTPM]":"27.4","Blood RNA - neutrophil [nTPM]":"9.3","Blood RNA - NK-cell [nTPM]":"38.0","Blood RNA - non-classical monocyte [nTPM]":"28.4","Blood RNA - plasmacytoid DC [nTPM]":"79.9","Blood RNA - T-reg [nTPM]":"38.3","Blood RNA - total PBMC [nTPM]":"36.0","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"14.6","Brain RNA - cerebellum [nTPM]":"16.6","Brain RNA - cerebral cortex [nTPM]":"18.4","Brain RNA - hippocampal formation [nTPM]":"14.5","Brain RNA - hypothalamus [nTPM]":"15.0","Brain RNA - medulla oblongata [nTPM]":"14.7","Brain RNA - midbrain [nTPM]":"16.1","Brain RNA - pons [nTPM]":"15.1","Brain RNA - spinal cord [nTPM]":"14.8","Brain RNA - thalamus [nTPM]":"14.7","Brain RNA - white matter [nTPM]":"16.9","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.9","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"22.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"56.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"35.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"50.3","Single Cell Type RNA - dendritic cells [nTPM]":"30.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"36.1","Single Cell Type RNA - Early spermatids [nTPM]":"28.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.9","Single Cell Type RNA - Endothelial cells [nTPM]":"19.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.2","Single Cell Type RNA - Fibroblasts [nTPM]":"30.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.4","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"55.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.3","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"25.8","Single Cell Type RNA - Langerhans cells [nTPM]":"45.4","Single Cell Type RNA - Late spermatids [nTPM]":"20.3","Single Cell Type RNA - Leydig cells [nTPM]":"26.8","Single Cell Type RNA - Macrophages [nTPM]":"23.0","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"64.2","Single Cell Type RNA - Muller glia cells [nTPM]":"15.5","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.9","Single Cell Type RNA - Paneth cells [nTPM]":"16.0","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"47.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.2","Single Cell Type RNA - Spermatocytes [nTPM]":"22.6","Single Cell Type RNA - Spermatogonia [nTPM]":"24.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"89.2","Single Cell Type RNA - T-cells [nTPM]":"16.6","Single Cell Type RNA - Theca cells [nTPM]":"25.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.8","Single Cell Type RNA - Urothelial cells [nTPM]":"31.3"},{"Gene":"ALS2","Gene synonym":["ALS2CR6"],"Ensembl":"ENSG00000003393","Gene description":"Alsin Rho guanine nucleotide exchange factor ALS2","Uniprot":["Q96Q42"],"Chromosome":"2","Position":"201700267-201782112","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Amyotrophic lateral sclerosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"91.8","granulocytes":"46.9","Inhibitory neurons":"66.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"26.4"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"23.0","eosinophil":"6.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"23.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"50.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"87.8"},"Antibody":["HPA046588"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Intermediate filaments","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046588":"AB_2679709"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"5.5","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"26.4","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"6.6","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"6.6","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"3.8","Tissue RNA - heart muscle [nTPM]":"13.7","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"6.7","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"6.0","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"10.0","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"13.5","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"5.3","Tissue RNA - stomach 1 [nTPM]":"6.8","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"1.4","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"6.2","Tissue RNA - vagina [nTPM]":"5.7","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"6.5","Cell RNA - A549 [nTPM]":"6.7","Cell RNA - AF22 [nTPM]":"7.1","Cell RNA - AN3-CA [nTPM]":"5.6","Cell RNA - ASC diff [nTPM]":"7.0","Cell RNA - ASC TERT1 [nTPM]":"5.1","Cell RNA - BEWO [nTPM]":"7.2","Cell RNA - BJ [nTPM]":"8.6","Cell RNA - BJ hTERT+ [nTPM]":"10.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.2","Cell RNA - CACO-2 [nTPM]":"5.8","Cell RNA - CAPAN-2 [nTPM]":"8.4","Cell RNA - Daudi [nTPM]":"1.2","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"11.7","Cell RNA - GAMG [nTPM]":"6.1","Cell RNA - HaCaT [nTPM]":"3.7","Cell RNA - HAP1 [nTPM]":"4.6","Cell RNA - HBEC3-KT [nTPM]":"10.6","Cell RNA - HBF TERT88 [nTPM]":"18.0","Cell RNA - HDLM-2 [nTPM]":"3.5","Cell RNA - HEK 293 [nTPM]":"4.8","Cell RNA - HEL [nTPM]":"15.3","Cell RNA - HeLa [nTPM]":"6.2","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"16.4","Cell RNA - HMC-1 [nTPM]":"50.4","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"4.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.5","Cell RNA - hTERT-HME1 [nTPM]":"14.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.7","Cell RNA - HUVEC TERT2 [nTPM]":"10.0","Cell RNA - JURKAT [nTPM]":"8.6","Cell RNA - K-562 [nTPM]":"9.8","Cell RNA - Karpas-707 [nTPM]":"5.7","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"7.5","Cell RNA - MOLT-4 [nTPM]":"6.7","Cell RNA - NB-4 [nTPM]":"20.3","Cell RNA - NTERA-2 [nTPM]":"9.2","Cell RNA - OE19 [nTPM]":"4.6","Cell RNA - PC-3 [nTPM]":"5.3","Cell RNA - REH [nTPM]":"5.4","Cell RNA - RH-30 [nTPM]":"7.7","Cell RNA - RPMI-8226 [nTPM]":"4.2","Cell RNA - RPTEC TERT1 [nTPM]":"9.8","Cell RNA - RT4 [nTPM]":"8.8","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"6.4","Cell RNA - SK-BR-3 [nTPM]":"7.1","Cell RNA - SK-MEL-30 [nTPM]":"9.2","Cell RNA - SuSa [nTPM]":"14.3","Cell RNA - T-47d [nTPM]":"5.4","Cell RNA - THP-1 [nTPM]":"7.2","Cell RNA - TIME [nTPM]":"7.9","Cell RNA - U-138 MG [nTPM]":"11.6","Cell RNA - U-2 OS [nTPM]":"7.2","Cell RNA - U-2197 [nTPM]":"3.5","Cell RNA - U-251 MG [nTPM]":"6.2","Cell RNA - U-266\/70 [nTPM]":"7.1","Cell RNA - U-266\/84 [nTPM]":"9.2","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"8.5","Cell RNA - U-937 [nTPM]":"3.4","Cell RNA - WM-115 [nTPM]":"7.2","Blood RNA - basophil [nTPM]":"23.0","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"6.8","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"26.4","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"1.4","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"7.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.7","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"15.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"32.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.9","Single Cell Type RNA - Early spermatids [nTPM]":"16.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.8","Single Cell Type RNA - Endothelial cells [nTPM]":"10.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"91.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"6.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.8","Single Cell Type RNA - granulocytes [nTPM]":"46.9","Single Cell Type RNA - Granulosa cells [nTPM]":"10.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"20.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"66.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.5","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"4.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"5.9","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.9","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"2.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.4","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"5.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"3.9","Single Cell Type RNA - Theca cells [nTPM]":"5.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.7"},{"Gene":"AMPD2","Gene synonym":["SPG63"],"Ensembl":"ENSG00000116337","Gene description":"Adenosine monophosphate deaminase 2","Uniprot":["Q01433"],"Chromosome":"1","Position":"109616104-109632051","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Nucleotide metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"62.6","Horizontal cells":"52.2","Macrophages":"52.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"19.4","eosinophil":"19.2","intermediate monocyte":"40.7","myeloid DC":"18.9","neutrophil":"61.1","non-classical monocyte":"44.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"18.9","granulocytes":"61.1","monocytes":"44.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027137","HPA045760"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027137":"AB_2672129","HPA045760":"AB_2679443"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.78e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"17.5","Tissue RNA - amygdala [nTPM]":"31.2","Tissue RNA - appendix [nTPM]":"12.0","Tissue RNA - basal ganglia [nTPM]":"41.6","Tissue RNA - bone marrow [nTPM]":"28.6","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"22.9","Tissue RNA - cerebral cortex [nTPM]":"34.7","Tissue RNA - cervix [nTPM]":"13.1","Tissue RNA - choroid plexus [nTPM]":"36.6","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"10.7","Tissue RNA - endometrium 1 [nTPM]":"11.5","Tissue RNA - epididymis [nTPM]":"4.1","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"34.8","Tissue RNA - hypothalamus [nTPM]":"37.0","Tissue RNA - kidney [nTPM]":"10.5","Tissue RNA - liver [nTPM]":"16.2","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"34.7","Tissue RNA - midbrain [nTPM]":"31.7","Tissue RNA - ovary [nTPM]":"17.5","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"45.8","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"33.6","Tissue RNA - prostate [nTPM]":"10.8","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"10.5","Tissue RNA - salivary gland [nTPM]":"9.2","Tissue RNA - seminal vesicle [nTPM]":"12.0","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"8.5","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"27.9","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"39.3","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"10.6","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"7.5","Tissue RNA - vagina [nTPM]":"11.4","Tissue RNA - white matter [nTPM]":"29.0","Cell RNA - A-431 [nTPM]":"20.6","Cell RNA - A549 [nTPM]":"22.5","Cell RNA - AF22 [nTPM]":"20.5","Cell RNA - AN3-CA [nTPM]":"20.1","Cell RNA - ASC diff [nTPM]":"18.0","Cell RNA - ASC TERT1 [nTPM]":"18.7","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"25.6","Cell RNA - BJ hTERT+ [nTPM]":"57.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.0","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"7.0","Cell RNA - Daudi [nTPM]":"10.5","Cell RNA - EFO-21 [nTPM]":"21.8","Cell RNA - fHDF\/TERT166 [nTPM]":"39.1","Cell RNA - GAMG [nTPM]":"16.0","Cell RNA - HaCaT [nTPM]":"11.3","Cell RNA - HAP1 [nTPM]":"15.8","Cell RNA - HBEC3-KT [nTPM]":"20.0","Cell RNA - HBF TERT88 [nTPM]":"13.4","Cell RNA - HDLM-2 [nTPM]":"13.0","Cell RNA - HEK 293 [nTPM]":"20.7","Cell RNA - HEL [nTPM]":"46.0","Cell RNA - HeLa [nTPM]":"15.6","Cell RNA - Hep G2 [nTPM]":"19.3","Cell RNA - HHSteC [nTPM]":"24.9","Cell RNA - HL-60 [nTPM]":"15.7","Cell RNA - HMC-1 [nTPM]":"45.7","Cell RNA - HSkMC [nTPM]":"23.3","Cell RNA - hTCEpi [nTPM]":"13.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.5","Cell RNA - hTERT-HME1 [nTPM]":"24.1","Cell RNA - hTERT-RPE1 [nTPM]":"28.2","Cell RNA - HUVEC TERT2 [nTPM]":"26.7","Cell RNA - JURKAT [nTPM]":"17.0","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"13.0","Cell RNA - LHCN-M2 [nTPM]":"16.0","Cell RNA - MCF7 [nTPM]":"23.2","Cell RNA - MOLT-4 [nTPM]":"26.7","Cell RNA - NB-4 [nTPM]":"29.0","Cell RNA - NTERA-2 [nTPM]":"20.6","Cell RNA - OE19 [nTPM]":"17.1","Cell RNA - PC-3 [nTPM]":"22.9","Cell RNA - REH [nTPM]":"18.6","Cell RNA - RH-30 [nTPM]":"15.8","Cell RNA - RPMI-8226 [nTPM]":"17.3","Cell RNA - RPTEC TERT1 [nTPM]":"24.2","Cell RNA - RT4 [nTPM]":"8.7","Cell RNA - SCLC-21H [nTPM]":"19.3","Cell RNA - SH-SY5Y [nTPM]":"22.4","Cell RNA - SiHa [nTPM]":"17.4","Cell RNA - SK-BR-3 [nTPM]":"19.8","Cell RNA - SK-MEL-30 [nTPM]":"24.6","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"10.4","Cell RNA - THP-1 [nTPM]":"16.2","Cell RNA - TIME [nTPM]":"16.7","Cell RNA - U-138 MG [nTPM]":"27.7","Cell RNA - U-2 OS [nTPM]":"39.0","Cell RNA - U-2197 [nTPM]":"33.7","Cell RNA - U-251 MG [nTPM]":"25.4","Cell RNA - U-266\/70 [nTPM]":"48.4","Cell RNA - U-266\/84 [nTPM]":"28.4","Cell RNA - U-698 [nTPM]":"12.1","Cell RNA - U-87 MG [nTPM]":"50.8","Cell RNA - U-937 [nTPM]":"25.9","Cell RNA - WM-115 [nTPM]":"35.1","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"19.4","Blood RNA - eosinophil [nTPM]":"19.2","Blood RNA - gdT-cell [nTPM]":"5.3","Blood RNA - intermediate monocyte [nTPM]":"40.7","Blood RNA - MAIT T-cell [nTPM]":"8.0","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"5.2","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"18.9","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"6.4","Blood RNA - naive CD8 T-cell [nTPM]":"5.1","Blood RNA - neutrophil [nTPM]":"61.1","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"44.6","Blood RNA - plasmacytoid DC [nTPM]":"2.6","Blood RNA - T-reg [nTPM]":"4.0","Blood RNA - total PBMC [nTPM]":"12.3","Brain RNA - amygdala [nTPM]":"31.2","Brain RNA - basal ganglia [nTPM]":"41.6","Brain RNA - cerebellum [nTPM]":"22.9","Brain RNA - cerebral cortex [nTPM]":"34.7","Brain RNA - hippocampal formation [nTPM]":"34.8","Brain RNA - hypothalamus [nTPM]":"37.0","Brain RNA - medulla oblongata [nTPM]":"34.7","Brain RNA - midbrain [nTPM]":"31.7","Brain RNA - pons [nTPM]":"33.6","Brain RNA - spinal cord [nTPM]":"27.9","Brain RNA - thalamus [nTPM]":"39.3","Brain RNA - white matter [nTPM]":"29.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"9.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"41.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"5.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - dendritic cells [nTPM]":"10.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.4","Single Cell Type RNA - Endothelial cells [nTPM]":"7.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.5","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"11.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"20.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.8","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"42.1","Single Cell Type RNA - Langerhans cells [nTPM]":"42.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"52.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"16.1","Single Cell Type RNA - Muller glia cells [nTPM]":"10.5","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.3","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"11.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"15.4","Single Cell Type RNA - Theca cells [nTPM]":"8.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.7","Single Cell Type RNA - Urothelial cells [nTPM]":"4.0"},{"Gene":"ANG","Gene synonym":["RAA1","RNASE5"],"Ensembl":"ENSG00000214274","Gene description":"Angiogenin","Uniprot":["P03950"],"Chromosome":"14","Position":"20684177-20698971","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Angiogenesis","Differentiation","Stress response"],"Molecular function":["Developmental protein","DNA-binding","Endonuclease","Hydrolase","Nuclease","Protein synthesis inhibitor"],"Disease involvement":["Amyotrophic lateral sclerosis","Cancer-related genes","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"52","RNA tissue specific nTPM":{"liver":"3018.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"24","RNA single cell type specific nTPM":{"Hepatocytes":"4816.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"liver cancer":"279.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"24.5","myeloid DC":"14.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Hep G2":"152.2","OE19":"116.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055896"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nucleoli rim","Mitotic chromosome","Actin filaments"],"Secretome location":"Secreted to blood","CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":308000000,"Blood concentration - Conc. blood MS [pg\/L]":"410000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Nucleoli","Nucleoli rim","Mitotic chromosome"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA055896":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.85e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.83e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"37.6","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"37.8","Tissue RNA - cerebellum [nTPM]":"3.5","Tissue RNA - cerebral cortex [nTPM]":"4.9","Tissue RNA - cervix [nTPM]":"38.2","Tissue RNA - choroid plexus [nTPM]":"5.6","Tissue RNA - colon [nTPM]":"32.6","Tissue RNA - duodenum [nTPM]":"23.2","Tissue RNA - endometrium 1 [nTPM]":"23.4","Tissue RNA - epididymis [nTPM]":"17.9","Tissue RNA - esophagus [nTPM]":"9.8","Tissue RNA - fallopian tube [nTPM]":"30.5","Tissue RNA - gallbladder [nTPM]":"28.5","Tissue RNA - heart muscle [nTPM]":"16.9","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"18.4","Tissue RNA - liver [nTPM]":"3018.1","Tissue RNA - lung [nTPM]":"18.5","Tissue RNA - lymph node [nTPM]":"3.5","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"58.1","Tissue RNA - pancreas [nTPM]":"30.8","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"4.3","Tissue RNA - prostate [nTPM]":"32.7","Tissue RNA - rectum [nTPM]":"45.7","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"52.6","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"6.2","Tissue RNA - skin 1 [nTPM]":"27.4","Tissue RNA - small intestine [nTPM]":"27.1","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"58.2","Tissue RNA - testis [nTPM]":"10.2","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"10.5","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"24.8","Tissue RNA - vagina [nTPM]":"31.4","Tissue RNA - white matter [nTPM]":"4.8","Cell RNA - A-431 [nTPM]":"3.7","Cell RNA - A549 [nTPM]":"9.9","Cell RNA - AF22 [nTPM]":"2.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"23.9","Cell RNA - ASC TERT1 [nTPM]":"27.8","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"4.8","Cell RNA - BJ hTERT+ [nTPM]":"8.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.0","Cell RNA - CACO-2 [nTPM]":"5.9","Cell RNA - CAPAN-2 [nTPM]":"5.1","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"12.0","Cell RNA - GAMG [nTPM]":"8.0","Cell RNA - HaCaT [nTPM]":"3.8","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"3.1","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"18.4","Cell RNA - HEK 293 [nTPM]":"3.8","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"5.1","Cell RNA - Hep G2 [nTPM]":"152.2","Cell RNA - HHSteC [nTPM]":"5.0","Cell RNA - HL-60 [nTPM]":"4.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"22.2","Cell RNA - hTCEpi [nTPM]":"2.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.5","Cell RNA - hTERT-HME1 [nTPM]":"5.1","Cell RNA - hTERT-RPE1 [nTPM]":"11.8","Cell RNA - HUVEC TERT2 [nTPM]":"5.7","Cell RNA - JURKAT [nTPM]":"4.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"27.0","Cell RNA - LHCN-M2 [nTPM]":"3.5","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"116.1","Cell RNA - PC-3 [nTPM]":"10.7","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"3.9","Cell RNA - RPMI-8226 [nTPM]":"11.3","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"4.6","Cell RNA - SK-BR-3 [nTPM]":"1.7","Cell RNA - SK-MEL-30 [nTPM]":"6.5","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"4.0","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"6.0","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"3.2","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"5.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"24.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"2.9","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"5.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"14.5","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"7.1","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"3.5","Brain RNA - cerebral cortex [nTPM]":"4.9","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"4.3","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"4.8","Single Cell Type RNA - Adipocytes [nTPM]":"9.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"9.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"194.5","Single Cell Type RNA - Club cells [nTPM]":"24.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"40.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.7","Single Cell Type RNA - Endothelial cells [nTPM]":"11.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"71.0","Single Cell Type RNA - Erythroid cells [nTPM]":"27.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"48.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"62.4","Single Cell Type RNA - Hepatocytes [nTPM]":"4816.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"171.9","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"95.9","Single Cell Type RNA - Langerhans cells [nTPM]":"18.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"71.1","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"10.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.6","Single Cell Type RNA - Paneth cells [nTPM]":"33.3","Single Cell Type RNA - Peritubular cells [nTPM]":"24.0","Single Cell Type RNA - Plasma cells [nTPM]":"11.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"91.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"61.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"76.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"52.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.6","Single Cell Type RNA - Urothelial cells [nTPM]":"39.2"},{"Gene":"ANO10","Gene synonym":["FLJ10375","MGC47890","SCAR10","TMEM16K"],"Ensembl":"ENSG00000160746","Gene description":"Anoctamin 10","Uniprot":["Q9NW15"],"Chromosome":"3","Position":"43354859-43691594","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"123.3","Excitatory neurons":"77.4","Inhibitory neurons":"97.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016624","HPA051569"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA016624":null,"HPA051569":"AB_2681537"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.70e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.41e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"26.6","Tissue RNA - adrenal gland [nTPM]":"14.1","Tissue RNA - amygdala [nTPM]":"17.6","Tissue RNA - appendix [nTPM]":"15.1","Tissue RNA - basal ganglia [nTPM]":"18.6","Tissue RNA - bone marrow [nTPM]":"33.0","Tissue RNA - breast [nTPM]":"21.8","Tissue RNA - cerebellum [nTPM]":"23.9","Tissue RNA - cerebral cortex [nTPM]":"20.9","Tissue RNA - cervix [nTPM]":"22.3","Tissue RNA - choroid plexus [nTPM]":"18.4","Tissue RNA - colon [nTPM]":"39.4","Tissue RNA - duodenum [nTPM]":"61.1","Tissue RNA - endometrium 1 [nTPM]":"21.6","Tissue RNA - epididymis [nTPM]":"13.6","Tissue RNA - esophagus [nTPM]":"25.3","Tissue RNA - fallopian tube [nTPM]":"13.9","Tissue RNA - gallbladder [nTPM]":"19.4","Tissue RNA - heart muscle [nTPM]":"12.7","Tissue RNA - hippocampal formation [nTPM]":"18.1","Tissue RNA - hypothalamus [nTPM]":"21.1","Tissue RNA - kidney [nTPM]":"29.9","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"16.9","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"22.7","Tissue RNA - midbrain [nTPM]":"22.9","Tissue RNA - ovary [nTPM]":"13.9","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"23.7","Tissue RNA - pituitary gland [nTPM]":"13.9","Tissue RNA - placenta [nTPM]":"18.1","Tissue RNA - pons [nTPM]":"23.2","Tissue RNA - prostate [nTPM]":"14.2","Tissue RNA - rectum [nTPM]":"33.7","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"28.6","Tissue RNA - seminal vesicle [nTPM]":"20.2","Tissue RNA - skeletal muscle [nTPM]":"15.5","Tissue RNA - skin 1 [nTPM]":"32.0","Tissue RNA - small intestine [nTPM]":"54.7","Tissue RNA - smooth muscle [nTPM]":"28.0","Tissue RNA - spinal cord [nTPM]":"19.6","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"13.5","Tissue RNA - testis [nTPM]":"13.0","Tissue RNA - thalamus [nTPM]":"19.8","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"24.5","Tissue RNA - tongue [nTPM]":"11.6","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"21.5","Tissue RNA - white matter [nTPM]":"24.1","Cell RNA - A-431 [nTPM]":"30.6","Cell RNA - A549 [nTPM]":"23.6","Cell RNA - AF22 [nTPM]":"26.1","Cell RNA - AN3-CA [nTPM]":"27.4","Cell RNA - ASC diff [nTPM]":"101.1","Cell RNA - ASC TERT1 [nTPM]":"53.5","Cell RNA - BEWO [nTPM]":"31.2","Cell RNA - BJ [nTPM]":"87.7","Cell RNA - BJ hTERT+ [nTPM]":"141.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"54.4","Cell RNA - CACO-2 [nTPM]":"16.2","Cell RNA - CAPAN-2 [nTPM]":"27.5","Cell RNA - Daudi [nTPM]":"3.1","Cell RNA - EFO-21 [nTPM]":"27.4","Cell RNA - fHDF\/TERT166 [nTPM]":"114.8","Cell RNA - GAMG [nTPM]":"43.1","Cell RNA - HaCaT [nTPM]":"16.3","Cell RNA - HAP1 [nTPM]":"20.6","Cell RNA - HBEC3-KT [nTPM]":"47.0","Cell RNA - HBF TERT88 [nTPM]":"52.6","Cell RNA - HDLM-2 [nTPM]":"33.6","Cell RNA - HEK 293 [nTPM]":"14.2","Cell RNA - HEL [nTPM]":"39.4","Cell RNA - HeLa [nTPM]":"28.7","Cell RNA - Hep G2 [nTPM]":"17.7","Cell RNA - HHSteC [nTPM]":"43.9","Cell RNA - HL-60 [nTPM]":"7.2","Cell RNA - HMC-1 [nTPM]":"31.1","Cell RNA - HSkMC [nTPM]":"50.5","Cell RNA - hTCEpi [nTPM]":"36.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"53.6","Cell RNA - hTERT-HME1 [nTPM]":"71.8","Cell RNA - hTERT-RPE1 [nTPM]":"79.4","Cell RNA - HUVEC TERT2 [nTPM]":"100.3","Cell RNA - JURKAT [nTPM]":"18.7","Cell RNA - K-562 [nTPM]":"30.8","Cell RNA - Karpas-707 [nTPM]":"24.9","Cell RNA - LHCN-M2 [nTPM]":"95.2","Cell RNA - MCF7 [nTPM]":"20.8","Cell RNA - MOLT-4 [nTPM]":"7.8","Cell RNA - NB-4 [nTPM]":"5.2","Cell RNA - NTERA-2 [nTPM]":"31.3","Cell RNA - OE19 [nTPM]":"23.7","Cell RNA - PC-3 [nTPM]":"28.6","Cell RNA - REH [nTPM]":"6.3","Cell RNA - RH-30 [nTPM]":"18.7","Cell RNA - RPMI-8226 [nTPM]":"10.2","Cell RNA - RPTEC TERT1 [nTPM]":"85.5","Cell RNA - RT4 [nTPM]":"31.4","Cell RNA - SCLC-21H [nTPM]":"6.4","Cell RNA - SH-SY5Y [nTPM]":"19.4","Cell RNA - SiHa [nTPM]":"34.4","Cell RNA - SK-BR-3 [nTPM]":"27.0","Cell RNA - SK-MEL-30 [nTPM]":"19.8","Cell RNA - SuSa [nTPM]":"45.3","Cell RNA - T-47d [nTPM]":"59.5","Cell RNA - THP-1 [nTPM]":"14.5","Cell RNA - TIME [nTPM]":"84.7","Cell RNA - U-138 MG [nTPM]":"66.2","Cell RNA - U-2 OS [nTPM]":"24.4","Cell RNA - U-2197 [nTPM]":"70.2","Cell RNA - U-251 MG [nTPM]":"40.7","Cell RNA - U-266\/70 [nTPM]":"15.7","Cell RNA - U-266\/84 [nTPM]":"22.9","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"60.2","Cell RNA - U-937 [nTPM]":"14.6","Cell RNA - WM-115 [nTPM]":"44.2","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"19.0","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"6.7","Blood RNA - intermediate monocyte [nTPM]":"11.1","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"4.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.5","Blood RNA - myeloid DC [nTPM]":"13.1","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"3.9","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"32.8","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"12.7","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"5.4","Blood RNA - total PBMC [nTPM]":"7.0","Brain RNA - amygdala [nTPM]":"17.6","Brain RNA - basal ganglia [nTPM]":"18.6","Brain RNA - cerebellum [nTPM]":"23.9","Brain RNA - cerebral cortex [nTPM]":"20.9","Brain RNA - hippocampal formation [nTPM]":"18.1","Brain RNA - hypothalamus [nTPM]":"21.1","Brain RNA - medulla oblongata [nTPM]":"22.7","Brain RNA - midbrain [nTPM]":"22.9","Brain RNA - pons [nTPM]":"23.2","Brain RNA - spinal cord [nTPM]":"19.6","Brain RNA - thalamus [nTPM]":"19.8","Brain RNA - white matter [nTPM]":"24.1","Single Cell Type RNA - Adipocytes [nTPM]":"24.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"70.2","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"8.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"13.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.4","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"123.3","Single Cell Type RNA - Ductal cells [nTPM]":"21.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.6","Single Cell Type RNA - Endothelial cells [nTPM]":"17.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"11.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"77.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.5","Single Cell Type RNA - Fibroblasts [nTPM]":"10.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.6","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"97.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"5.2","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"69.3","Single Cell Type RNA - monocytes [nTPM]":"9.2","Single Cell Type RNA - Muller glia cells [nTPM]":"17.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"71.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"22.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"58.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.7","Single Cell Type RNA - Spermatocytes [nTPM]":"17.1","Single Cell Type RNA - Spermatogonia [nTPM]":"23.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.1","Single Cell Type RNA - T-cells [nTPM]":"5.8","Single Cell Type RNA - Theca cells [nTPM]":"6.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"ANO3","Gene synonym":["C11orf25","DYT23","GENX-3947","TMEM16C"],"Ensembl":"ENSG00000134343","Gene description":"Anoctamin 3","Uniprot":["Q9BYT9"],"Chromosome":"11","Position":"26188842-26663289","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"brain":"59.2","epididymis":"57.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"201.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"59.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"1.9","HDLM-2":"6.8","U-2 OS":"1.6","U-2197":"4.3"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"158.9"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"basal ganglia":"180.1"},"Antibody":["HPA041629"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041629":"AB_10793969"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"59.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"11.8","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"57.4","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.1","Cell RNA - GAMG [nTPM]":"1.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"6.8","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"4.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"59.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"11.8","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"12.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"201.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ANXA11","Gene synonym":["ANX11"],"Ensembl":"ENSG00000122359","Gene description":"Annexin A11","Uniprot":["P50995"],"Chromosome":"10","Position":"80150889-80205572","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","Cell division"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Cancer-related genes","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"443.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004851","HPA027545"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004851":"AB_626682","HPA027545":"AB_1844851"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"139.9","Tissue RNA - adrenal gland [nTPM]":"29.5","Tissue RNA - amygdala [nTPM]":"39.0","Tissue RNA - appendix [nTPM]":"99.4","Tissue RNA - basal ganglia [nTPM]":"40.6","Tissue RNA - bone marrow [nTPM]":"192.9","Tissue RNA - breast [nTPM]":"107.6","Tissue RNA - cerebellum [nTPM]":"27.5","Tissue RNA - cerebral cortex [nTPM]":"46.8","Tissue RNA - cervix [nTPM]":"86.6","Tissue RNA - choroid plexus [nTPM]":"52.8","Tissue RNA - colon [nTPM]":"130.3","Tissue RNA - duodenum [nTPM]":"138.0","Tissue RNA - endometrium 1 [nTPM]":"74.3","Tissue RNA - epididymis [nTPM]":"107.5","Tissue RNA - esophagus [nTPM]":"210.2","Tissue RNA - fallopian tube [nTPM]":"109.0","Tissue RNA - gallbladder [nTPM]":"84.8","Tissue RNA - heart muscle [nTPM]":"236.2","Tissue RNA - hippocampal formation [nTPM]":"47.3","Tissue RNA - hypothalamus [nTPM]":"29.0","Tissue RNA - kidney [nTPM]":"144.7","Tissue RNA - liver [nTPM]":"47.7","Tissue RNA - lung [nTPM]":"109.5","Tissue RNA - lymph node [nTPM]":"81.2","Tissue RNA - medulla oblongata [nTPM]":"26.4","Tissue RNA - midbrain [nTPM]":"26.6","Tissue RNA - ovary [nTPM]":"78.2","Tissue RNA - pancreas [nTPM]":"95.4","Tissue RNA - parathyroid gland [nTPM]":"81.8","Tissue RNA - pituitary gland [nTPM]":"27.2","Tissue RNA - placenta [nTPM]":"91.1","Tissue RNA - pons [nTPM]":"23.9","Tissue RNA - prostate [nTPM]":"100.3","Tissue RNA - rectum [nTPM]":"120.7","Tissue RNA - retina [nTPM]":"4.8","Tissue RNA - salivary gland [nTPM]":"94.1","Tissue RNA - seminal vesicle [nTPM]":"81.8","Tissue RNA - skeletal muscle [nTPM]":"188.9","Tissue RNA - skin 1 [nTPM]":"75.6","Tissue RNA - small intestine [nTPM]":"137.2","Tissue RNA - smooth muscle [nTPM]":"86.0","Tissue RNA - spinal cord [nTPM]":"25.4","Tissue RNA - spleen [nTPM]":"76.2","Tissue RNA - stomach 1 [nTPM]":"139.3","Tissue RNA - testis [nTPM]":"24.5","Tissue RNA - thalamus [nTPM]":"24.6","Tissue RNA - thymus [nTPM]":"100.2","Tissue RNA - thyroid gland [nTPM]":"61.4","Tissue RNA - tongue [nTPM]":"166.2","Tissue RNA - tonsil [nTPM]":"101.7","Tissue RNA - urinary bladder [nTPM]":"148.1","Tissue RNA - vagina [nTPM]":"102.8","Tissue RNA - white matter [nTPM]":"30.4","Cell RNA - A-431 [nTPM]":"221.7","Cell RNA - A549 [nTPM]":"195.7","Cell RNA - AF22 [nTPM]":"10.4","Cell RNA - AN3-CA [nTPM]":"53.9","Cell RNA - ASC diff [nTPM]":"220.2","Cell RNA - ASC TERT1 [nTPM]":"201.1","Cell RNA - BEWO [nTPM]":"119.6","Cell RNA - BJ [nTPM]":"149.5","Cell RNA - BJ hTERT+ [nTPM]":"397.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"95.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"98.8","Cell RNA - CACO-2 [nTPM]":"168.7","Cell RNA - CAPAN-2 [nTPM]":"338.2","Cell RNA - Daudi [nTPM]":"13.1","Cell RNA - EFO-21 [nTPM]":"113.6","Cell RNA - fHDF\/TERT166 [nTPM]":"236.7","Cell RNA - GAMG [nTPM]":"8.1","Cell RNA - HaCaT [nTPM]":"277.7","Cell RNA - HAP1 [nTPM]":"44.6","Cell RNA - HBEC3-KT [nTPM]":"136.2","Cell RNA - HBF TERT88 [nTPM]":"54.2","Cell RNA - HDLM-2 [nTPM]":"384.3","Cell RNA - HEK 293 [nTPM]":"76.0","Cell RNA - HEL [nTPM]":"84.4","Cell RNA - HeLa [nTPM]":"98.9","Cell RNA - Hep G2 [nTPM]":"131.5","Cell RNA - HHSteC [nTPM]":"129.4","Cell RNA - HL-60 [nTPM]":"92.0","Cell RNA - HMC-1 [nTPM]":"212.3","Cell RNA - HSkMC [nTPM]":"222.9","Cell RNA - hTCEpi [nTPM]":"74.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"57.8","Cell RNA - hTERT-HME1 [nTPM]":"39.4","Cell RNA - hTERT-RPE1 [nTPM]":"178.9","Cell RNA - HUVEC TERT2 [nTPM]":"143.9","Cell RNA - JURKAT [nTPM]":"117.9","Cell RNA - K-562 [nTPM]":"82.1","Cell RNA - Karpas-707 [nTPM]":"163.7","Cell RNA - LHCN-M2 [nTPM]":"76.8","Cell RNA - MCF7 [nTPM]":"127.3","Cell RNA - MOLT-4 [nTPM]":"119.8","Cell RNA - NB-4 [nTPM]":"200.9","Cell RNA - NTERA-2 [nTPM]":"19.6","Cell RNA - OE19 [nTPM]":"211.5","Cell RNA - PC-3 [nTPM]":"367.7","Cell RNA - REH [nTPM]":"91.7","Cell RNA - RH-30 [nTPM]":"14.9","Cell RNA - RPMI-8226 [nTPM]":"344.0","Cell RNA - RPTEC TERT1 [nTPM]":"155.1","Cell RNA - RT4 [nTPM]":"191.8","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"37.9","Cell RNA - SiHa [nTPM]":"65.0","Cell RNA - SK-BR-3 [nTPM]":"269.9","Cell RNA - SK-MEL-30 [nTPM]":"156.4","Cell RNA - SuSa [nTPM]":"83.4","Cell RNA - T-47d [nTPM]":"80.6","Cell RNA - THP-1 [nTPM]":"120.6","Cell RNA - TIME [nTPM]":"160.0","Cell RNA - U-138 MG [nTPM]":"68.7","Cell RNA - U-2 OS [nTPM]":"101.4","Cell RNA - U-2197 [nTPM]":"157.6","Cell RNA - U-251 MG [nTPM]":"84.4","Cell RNA - U-266\/70 [nTPM]":"91.7","Cell RNA - U-266\/84 [nTPM]":"145.6","Cell RNA - U-698 [nTPM]":"96.0","Cell RNA - U-87 MG [nTPM]":"66.6","Cell RNA - U-937 [nTPM]":"155.4","Cell RNA - WM-115 [nTPM]":"47.4","Blood RNA - basophil [nTPM]":"130.8","Blood RNA - classical monocyte [nTPM]":"66.8","Blood RNA - eosinophil [nTPM]":"443.8","Blood RNA - gdT-cell [nTPM]":"72.9","Blood RNA - intermediate monocyte [nTPM]":"52.4","Blood RNA - MAIT T-cell [nTPM]":"75.0","Blood RNA - memory B-cell [nTPM]":"64.9","Blood RNA - memory CD4 T-cell [nTPM]":"92.5","Blood RNA - memory CD8 T-cell [nTPM]":"100.5","Blood RNA - myeloid DC [nTPM]":"49.4","Blood RNA - naive B-cell [nTPM]":"54.2","Blood RNA - naive CD4 T-cell [nTPM]":"83.7","Blood RNA - naive CD8 T-cell [nTPM]":"74.4","Blood RNA - neutrophil [nTPM]":"231.8","Blood RNA - NK-cell [nTPM]":"61.3","Blood RNA - non-classical monocyte [nTPM]":"59.1","Blood RNA - plasmacytoid DC [nTPM]":"78.5","Blood RNA - T-reg [nTPM]":"126.5","Blood RNA - total PBMC [nTPM]":"85.4","Brain RNA - amygdala [nTPM]":"39.0","Brain RNA - basal ganglia [nTPM]":"40.6","Brain RNA - cerebellum [nTPM]":"27.5","Brain RNA - cerebral cortex [nTPM]":"46.8","Brain RNA - hippocampal formation [nTPM]":"47.3","Brain RNA - hypothalamus [nTPM]":"29.0","Brain RNA - medulla oblongata [nTPM]":"26.4","Brain RNA - midbrain [nTPM]":"26.6","Brain RNA - pons [nTPM]":"23.9","Brain RNA - spinal cord [nTPM]":"25.4","Brain RNA - thalamus [nTPM]":"24.6","Brain RNA - white matter [nTPM]":"30.4","Single Cell Type RNA - Adipocytes [nTPM]":"150.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"96.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"78.4","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"101.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"51.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"266.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"219.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"92.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"293.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"203.0","Single Cell Type RNA - Club cells [nTPM]":"227.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"220.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"271.7","Single Cell Type RNA - dendritic cells [nTPM]":"137.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"457.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"332.6","Single Cell Type RNA - Ductal cells [nTPM]":"429.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"180.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.7","Single Cell Type RNA - Endothelial cells [nTPM]":"82.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"77.5","Single Cell Type RNA - Erythroid cells [nTPM]":"29.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"352.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"309.8","Single Cell Type RNA - Fibroblasts [nTPM]":"113.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"175.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"265.7","Single Cell Type RNA - granulocytes [nTPM]":"116.1","Single Cell Type RNA - Granulosa cells [nTPM]":"81.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"91.4","Single Cell Type RNA - Hepatocytes [nTPM]":"40.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"228.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"186.9","Single Cell Type RNA - Ionocytes [nTPM]":"97.6","Single Cell Type RNA - Kupffer cells [nTPM]":"149.7","Single Cell Type RNA - Langerhans cells [nTPM]":"167.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.6","Single Cell Type RNA - Leydig cells [nTPM]":"92.9","Single Cell Type RNA - Macrophages [nTPM]":"155.0","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"208.2","Single Cell Type RNA - Muller glia cells [nTPM]":"38.9","Single Cell Type RNA - NK-cells [nTPM]":"159.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"420.6","Single Cell Type RNA - Paneth cells [nTPM]":"461.0","Single Cell Type RNA - Peritubular cells [nTPM]":"92.6","Single Cell Type RNA - Plasma cells [nTPM]":"98.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"414.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"367.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"156.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"229.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.8","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"137.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"51.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"98.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"42.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"185.5","Single Cell Type RNA - T-cells [nTPM]":"131.9","Single Cell Type RNA - Theca cells [nTPM]":"50.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"227.8","Single Cell Type RNA - Urothelial cells [nTPM]":"581.4"},{"Gene":"AP000812.4","Gene synonym":[],"Ensembl":"ENSG00000284922","Gene description":"Leucine rich transmembrane and O-methyltransferase domain containing","Uniprot":["Q8WZ04"],"Chromosome":"11","Position":"72080331-72110782","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Catecholamine metabolism","Hearing","Neurotransmitter degradation"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"fallopian tube":"14.1","testis":"9.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"2.9","HBEC3-KT":"2.9","MCF7":"3.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039949"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":null,"Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA039949":"AB_10960708"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":null,"Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"9.5","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":null,"Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"2.9","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.3","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"3.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"AP3B2","Gene synonym":["NAPTB"],"Ensembl":"ENSG00000103723","Gene description":"Adaptor related protein complex 3 subunit beta 2","Uniprot":["Q13367"],"Chromosome":"15","Position":"82659281-82710112","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"20.7","pituitary gland":"18.8","retina":"33.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"27.1","Excitatory neurons":"61.7","Inhibitory neurons":"56.9","Oligodendrocyte precursor cells":"44.7","Oligodendrocytes":"22.8","Rod photoreceptor cells":"58.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"9.5","NTERA-2":"9.5","RT4":"17.3","SCLC-21H":"29.0","SH-SY5Y":"17.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039467","HPA039818"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA039467":"AB_10795143","HPA039818":"AB_10795299"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"15.3","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"18.6","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"15.5","Tissue RNA - cerebral cortex [nTPM]":"20.7","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"19.6","Tissue RNA - hypothalamus [nTPM]":"5.5","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"12.7","Tissue RNA - pituitary gland [nTPM]":"18.8","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"33.0","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"2.1","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"11.3","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"3.2","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"5.7","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"4.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"1.8","Cell RNA - HaCaT [nTPM]":"0.9","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"3.2","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"1.0","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"2.5","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"9.5","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"17.3","Cell RNA - SCLC-21H [nTPM]":"29.0","Cell RNA - SH-SY5Y [nTPM]":"17.5","Cell RNA - SiHa [nTPM]":"3.2","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"2.4","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"1.6","Cell RNA - U-266\/84 [nTPM]":"8.8","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"2.2","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"15.3","Brain RNA - basal ganglia [nTPM]":"18.6","Brain RNA - cerebellum [nTPM]":"15.5","Brain RNA - cerebral cortex [nTPM]":"20.7","Brain RNA - hippocampal formation [nTPM]":"19.6","Brain RNA - hypothalamus [nTPM]":"5.5","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"11.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"20.9","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"18.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"8.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"44.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"9.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"AP4B1","Gene synonym":["BETA-4","SPG47"],"Ensembl":"ENSG00000134262","Gene description":"Adaptor related protein complex 4 subunit beta 1","Uniprot":["Q9Y6B7"],"Chromosome":"1","Position":"113894194-113905201","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"31.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"65.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028162","HPA028652"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA028162":"AB_10610976","HPA028652":"AB_10601451"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.60e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"8.5","Tissue RNA - amygdala [nTPM]":"12.5","Tissue RNA - appendix [nTPM]":"11.1","Tissue RNA - basal ganglia [nTPM]":"13.1","Tissue RNA - bone marrow [nTPM]":"20.5","Tissue RNA - breast [nTPM]":"9.3","Tissue RNA - cerebellum [nTPM]":"14.6","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"11.9","Tissue RNA - choroid plexus [nTPM]":"10.9","Tissue RNA - colon [nTPM]":"11.5","Tissue RNA - duodenum [nTPM]":"10.6","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"14.2","Tissue RNA - esophagus [nTPM]":"12.1","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"11.2","Tissue RNA - hippocampal formation [nTPM]":"13.0","Tissue RNA - hypothalamus [nTPM]":"13.0","Tissue RNA - kidney [nTPM]":"9.7","Tissue RNA - liver [nTPM]":"8.4","Tissue RNA - lung [nTPM]":"9.5","Tissue RNA - lymph node [nTPM]":"14.3","Tissue RNA - medulla oblongata [nTPM]":"11.6","Tissue RNA - midbrain [nTPM]":"11.4","Tissue RNA - ovary [nTPM]":"13.7","Tissue RNA - pancreas [nTPM]":"14.0","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"11.8","Tissue RNA - prostate [nTPM]":"9.6","Tissue RNA - rectum [nTPM]":"12.7","Tissue RNA - retina [nTPM]":"20.0","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"6.2","Tissue RNA - skeletal muscle [nTPM]":"11.7","Tissue RNA - skin 1 [nTPM]":"11.5","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"11.5","Tissue RNA - spleen [nTPM]":"20.1","Tissue RNA - stomach 1 [nTPM]":"10.4","Tissue RNA - testis [nTPM]":"11.1","Tissue RNA - thalamus [nTPM]":"13.3","Tissue RNA - thymus [nTPM]":"16.1","Tissue RNA - thyroid gland [nTPM]":"11.0","Tissue RNA - tongue [nTPM]":"9.1","Tissue RNA - tonsil [nTPM]":"13.9","Tissue RNA - urinary bladder [nTPM]":"9.2","Tissue RNA - vagina [nTPM]":"10.0","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"11.0","Cell RNA - A549 [nTPM]":"9.8","Cell RNA - AF22 [nTPM]":"10.0","Cell RNA - AN3-CA [nTPM]":"11.8","Cell RNA - ASC diff [nTPM]":"15.7","Cell RNA - ASC TERT1 [nTPM]":"14.1","Cell RNA - BEWO [nTPM]":"6.4","Cell RNA - BJ [nTPM]":"10.1","Cell RNA - BJ hTERT+ [nTPM]":"9.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.0","Cell RNA - CACO-2 [nTPM]":"6.8","Cell RNA - CAPAN-2 [nTPM]":"7.7","Cell RNA - Daudi [nTPM]":"21.5","Cell RNA - EFO-21 [nTPM]":"15.9","Cell RNA - fHDF\/TERT166 [nTPM]":"12.4","Cell RNA - GAMG [nTPM]":"6.5","Cell RNA - HaCaT [nTPM]":"9.7","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"13.4","Cell RNA - HBF TERT88 [nTPM]":"16.5","Cell RNA - HDLM-2 [nTPM]":"16.6","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"17.6","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"8.3","Cell RNA - HHSteC [nTPM]":"9.5","Cell RNA - HL-60 [nTPM]":"19.6","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"16.1","Cell RNA - hTCEpi [nTPM]":"6.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.5","Cell RNA - hTERT-HME1 [nTPM]":"15.3","Cell RNA - hTERT-RPE1 [nTPM]":"7.8","Cell RNA - HUVEC TERT2 [nTPM]":"22.7","Cell RNA - JURKAT [nTPM]":"20.9","Cell RNA - K-562 [nTPM]":"12.3","Cell RNA - Karpas-707 [nTPM]":"18.5","Cell RNA - LHCN-M2 [nTPM]":"17.6","Cell RNA - MCF7 [nTPM]":"65.2","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"21.6","Cell RNA - NTERA-2 [nTPM]":"9.4","Cell RNA - OE19 [nTPM]":"7.7","Cell RNA - PC-3 [nTPM]":"19.0","Cell RNA - REH [nTPM]":"15.0","Cell RNA - RH-30 [nTPM]":"19.5","Cell RNA - RPMI-8226 [nTPM]":"13.3","Cell RNA - RPTEC TERT1 [nTPM]":"13.2","Cell RNA - RT4 [nTPM]":"5.5","Cell RNA - SCLC-21H [nTPM]":"10.2","Cell RNA - SH-SY5Y [nTPM]":"8.5","Cell RNA - SiHa [nTPM]":"10.1","Cell RNA - SK-BR-3 [nTPM]":"19.1","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"9.5","Cell RNA - T-47d [nTPM]":"5.7","Cell RNA - THP-1 [nTPM]":"15.4","Cell RNA - TIME [nTPM]":"21.8","Cell RNA - U-138 MG [nTPM]":"15.0","Cell RNA - U-2 OS [nTPM]":"13.9","Cell RNA - U-2197 [nTPM]":"17.4","Cell RNA - U-251 MG [nTPM]":"20.8","Cell RNA - U-266\/70 [nTPM]":"15.2","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"21.3","Cell RNA - U-87 MG [nTPM]":"24.6","Cell RNA - U-937 [nTPM]":"26.0","Cell RNA - WM-115 [nTPM]":"25.1","Blood RNA - basophil [nTPM]":"15.9","Blood RNA - classical monocyte [nTPM]":"10.5","Blood RNA - eosinophil [nTPM]":"8.6","Blood RNA - gdT-cell [nTPM]":"14.7","Blood RNA - intermediate monocyte [nTPM]":"10.8","Blood RNA - MAIT T-cell [nTPM]":"15.6","Blood RNA - memory B-cell [nTPM]":"9.5","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.6","Blood RNA - myeloid DC [nTPM]":"12.9","Blood RNA - naive B-cell [nTPM]":"11.9","Blood RNA - naive CD4 T-cell [nTPM]":"12.7","Blood RNA - naive CD8 T-cell [nTPM]":"11.1","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"12.2","Blood RNA - non-classical monocyte [nTPM]":"8.5","Blood RNA - plasmacytoid DC [nTPM]":"9.1","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"9.5","Brain RNA - amygdala [nTPM]":"12.5","Brain RNA - basal ganglia [nTPM]":"13.1","Brain RNA - cerebellum [nTPM]":"14.6","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"13.0","Brain RNA - hypothalamus [nTPM]":"13.0","Brain RNA - medulla oblongata [nTPM]":"11.6","Brain RNA - midbrain [nTPM]":"11.4","Brain RNA - pons [nTPM]":"11.8","Brain RNA - spinal cord [nTPM]":"11.5","Brain RNA - thalamus [nTPM]":"13.3","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"7.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"12.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"11.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - dendritic cells [nTPM]":"12.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"4.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"6.9","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"6.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.9","Single Cell Type RNA - Paneth cells [nTPM]":"6.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"7.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.2","Single Cell Type RNA - Spermatocytes [nTPM]":"16.4","Single Cell Type RNA - Spermatogonia [nTPM]":"11.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"14.8","Single Cell Type RNA - Theca cells [nTPM]":"6.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"AP4E1","Gene synonym":["AP-4-EPSILON","SPG51"],"Ensembl":"ENSG00000081014","Gene description":"Adaptor related protein complex 4 subunit epsilon 1","Uniprot":["Q9UPM8"],"Chromosome":"15","Position":"50908672-51005895","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"36.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041749","HPA041891"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041749":"AB_10794490","HPA041891":"AB_10796462"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"3.1","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"4.7","Tissue RNA - fallopian tube [nTPM]":"3.2","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"5.5","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"5.1","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"3.8","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"8.2","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"11.5","Cell RNA - A549 [nTPM]":"8.7","Cell RNA - AF22 [nTPM]":"6.0","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"7.9","Cell RNA - ASC TERT1 [nTPM]":"12.0","Cell RNA - BEWO [nTPM]":"11.7","Cell RNA - BJ [nTPM]":"11.1","Cell RNA - BJ hTERT+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.1","Cell RNA - CACO-2 [nTPM]":"10.7","Cell RNA - CAPAN-2 [nTPM]":"1.8","Cell RNA - Daudi [nTPM]":"11.2","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"12.5","Cell RNA - GAMG [nTPM]":"10.8","Cell RNA - HaCaT [nTPM]":"13.7","Cell RNA - HAP1 [nTPM]":"9.0","Cell RNA - HBEC3-KT [nTPM]":"9.6","Cell RNA - HBF TERT88 [nTPM]":"12.4","Cell RNA - HDLM-2 [nTPM]":"12.3","Cell RNA - HEK 293 [nTPM]":"4.6","Cell RNA - HEL [nTPM]":"9.8","Cell RNA - HeLa [nTPM]":"14.5","Cell RNA - Hep G2 [nTPM]":"4.3","Cell RNA - HHSteC [nTPM]":"11.1","Cell RNA - HL-60 [nTPM]":"12.1","Cell RNA - HMC-1 [nTPM]":"8.2","Cell RNA - HSkMC [nTPM]":"12.2","Cell RNA - hTCEpi [nTPM]":"11.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.4","Cell RNA - hTERT-HME1 [nTPM]":"21.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.6","Cell RNA - HUVEC TERT2 [nTPM]":"7.2","Cell RNA - JURKAT [nTPM]":"8.8","Cell RNA - K-562 [nTPM]":"9.1","Cell RNA - Karpas-707 [nTPM]":"6.3","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"15.4","Cell RNA - MOLT-4 [nTPM]":"7.1","Cell RNA - NB-4 [nTPM]":"6.9","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"5.2","Cell RNA - PC-3 [nTPM]":"4.4","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"8.5","Cell RNA - RPMI-8226 [nTPM]":"6.9","Cell RNA - RPTEC TERT1 [nTPM]":"7.9","Cell RNA - RT4 [nTPM]":"10.4","Cell RNA - SCLC-21H [nTPM]":"4.1","Cell RNA - SH-SY5Y [nTPM]":"6.7","Cell RNA - SiHa [nTPM]":"11.8","Cell RNA - SK-BR-3 [nTPM]":"8.4","Cell RNA - SK-MEL-30 [nTPM]":"8.7","Cell RNA - SuSa [nTPM]":"10.7","Cell RNA - T-47d [nTPM]":"7.6","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"10.0","Cell RNA - U-138 MG [nTPM]":"15.7","Cell RNA - U-2 OS [nTPM]":"5.8","Cell RNA - U-2197 [nTPM]":"9.5","Cell RNA - U-251 MG [nTPM]":"15.9","Cell RNA - U-266\/70 [nTPM]":"9.6","Cell RNA - U-266\/84 [nTPM]":"11.7","Cell RNA - U-698 [nTPM]":"14.1","Cell RNA - U-87 MG [nTPM]":"12.3","Cell RNA - U-937 [nTPM]":"26.1","Cell RNA - WM-115 [nTPM]":"7.3","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.1","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"8.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"9.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"8.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.9","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"8.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"17.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"6.5","Single Cell Type RNA - Muller glia cells [nTPM]":"3.9","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"9.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"9.6","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.5","Single Cell Type RNA - Urothelial cells [nTPM]":"2.4"},{"Gene":"AP4M1","Gene synonym":["MU-4","MU-ARP2","SPG50"],"Ensembl":"ENSG00000221838","Gene description":"Adaptor related protein complex 4 subunit mu 1","Uniprot":["O00189"],"Chromosome":"7","Position":"100101549-100110345","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"95.9","Spermatocytes":"84.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066774"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066774":"AB_2685718"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.63e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.4","Tissue RNA - adrenal gland [nTPM]":"7.3","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"9.9","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"11.4","Tissue RNA - choroid plexus [nTPM]":"10.0","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"12.5","Tissue RNA - endometrium 1 [nTPM]":"15.7","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"9.8","Tissue RNA - hippocampal formation [nTPM]":"9.9","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"8.8","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"11.2","Tissue RNA - midbrain [nTPM]":"10.5","Tissue RNA - ovary [nTPM]":"9.3","Tissue RNA - pancreas [nTPM]":"12.3","Tissue RNA - parathyroid gland [nTPM]":"7.7","Tissue RNA - pituitary gland [nTPM]":"15.4","Tissue RNA - placenta [nTPM]":"5.6","Tissue RNA - pons [nTPM]":"10.7","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"10.1","Tissue RNA - seminal vesicle [nTPM]":"11.0","Tissue RNA - skeletal muscle [nTPM]":"10.7","Tissue RNA - skin 1 [nTPM]":"11.7","Tissue RNA - small intestine [nTPM]":"9.9","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"32.6","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"6.1","Tissue RNA - thyroid gland [nTPM]":"10.9","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"9.3","Cell RNA - A549 [nTPM]":"13.0","Cell RNA - AF22 [nTPM]":"13.9","Cell RNA - AN3-CA [nTPM]":"35.4","Cell RNA - ASC diff [nTPM]":"7.8","Cell RNA - ASC TERT1 [nTPM]":"17.8","Cell RNA - BEWO [nTPM]":"15.8","Cell RNA - BJ [nTPM]":"5.5","Cell RNA - BJ hTERT+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.9","Cell RNA - CACO-2 [nTPM]":"10.6","Cell RNA - CAPAN-2 [nTPM]":"23.7","Cell RNA - Daudi [nTPM]":"11.1","Cell RNA - EFO-21 [nTPM]":"25.2","Cell RNA - fHDF\/TERT166 [nTPM]":"13.4","Cell RNA - GAMG [nTPM]":"10.2","Cell RNA - HaCaT [nTPM]":"9.9","Cell RNA - HAP1 [nTPM]":"6.1","Cell RNA - HBEC3-KT [nTPM]":"12.0","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"8.9","Cell RNA - HEK 293 [nTPM]":"8.6","Cell RNA - HEL [nTPM]":"6.2","Cell RNA - HeLa [nTPM]":"12.7","Cell RNA - Hep G2 [nTPM]":"9.4","Cell RNA - HHSteC [nTPM]":"16.2","Cell RNA - HL-60 [nTPM]":"7.2","Cell RNA - HMC-1 [nTPM]":"10.9","Cell RNA - HSkMC [nTPM]":"15.1","Cell RNA - hTCEpi [nTPM]":"20.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.7","Cell RNA - hTERT-HME1 [nTPM]":"12.5","Cell RNA - hTERT-RPE1 [nTPM]":"13.7","Cell RNA - HUVEC TERT2 [nTPM]":"23.5","Cell RNA - JURKAT [nTPM]":"14.3","Cell RNA - K-562 [nTPM]":"11.9","Cell RNA - Karpas-707 [nTPM]":"8.4","Cell RNA - LHCN-M2 [nTPM]":"24.6","Cell RNA - MCF7 [nTPM]":"28.7","Cell RNA - MOLT-4 [nTPM]":"25.9","Cell RNA - NB-4 [nTPM]":"14.1","Cell RNA - NTERA-2 [nTPM]":"10.9","Cell RNA - OE19 [nTPM]":"8.4","Cell RNA - PC-3 [nTPM]":"13.3","Cell RNA - REH [nTPM]":"21.8","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"13.9","Cell RNA - RPTEC TERT1 [nTPM]":"18.0","Cell RNA - RT4 [nTPM]":"11.9","Cell RNA - SCLC-21H [nTPM]":"24.2","Cell RNA - SH-SY5Y [nTPM]":"21.1","Cell RNA - SiHa [nTPM]":"14.0","Cell RNA - SK-BR-3 [nTPM]":"40.9","Cell RNA - SK-MEL-30 [nTPM]":"11.9","Cell RNA - SuSa [nTPM]":"7.9","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"14.0","Cell RNA - TIME [nTPM]":"26.0","Cell RNA - U-138 MG [nTPM]":"21.2","Cell RNA - U-2 OS [nTPM]":"16.9","Cell RNA - U-2197 [nTPM]":"19.8","Cell RNA - U-251 MG [nTPM]":"9.4","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"6.8","Cell RNA - U-698 [nTPM]":"16.8","Cell RNA - U-87 MG [nTPM]":"17.7","Cell RNA - U-937 [nTPM]":"8.3","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"6.3","Blood RNA - eosinophil [nTPM]":"9.1","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"7.9","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.0","Blood RNA - memory CD8 T-cell [nTPM]":"5.1","Blood RNA - myeloid DC [nTPM]":"8.7","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"10.8","Blood RNA - plasmacytoid DC [nTPM]":"5.3","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"4.3","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"9.9","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"9.9","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"11.2","Brain RNA - midbrain [nTPM]":"10.5","Brain RNA - pons [nTPM]":"10.7","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"10.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"17.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"13.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.7","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.4","Single Cell Type RNA - Early spermatids [nTPM]":"69.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.6","Single Cell Type RNA - Endothelial cells [nTPM]":"12.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.1","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.2","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"22.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.9","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"7.7","Single Cell Type RNA - Late spermatids [nTPM]":"95.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"6.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"14.5","Single Cell Type RNA - Muller glia cells [nTPM]":"21.0","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.6","Single Cell Type RNA - Paneth cells [nTPM]":"17.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"5.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"67.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.4","Single Cell Type RNA - Spermatocytes [nTPM]":"84.7","Single Cell Type RNA - Spermatogonia [nTPM]":"39.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - T-cells [nTPM]":"8.2","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.2","Single Cell Type RNA - Urothelial cells [nTPM]":"11.2"},{"Gene":"AP4S1","Gene synonym":["AP47B","CLA20","SPG52"],"Ensembl":"ENSG00000100478","Gene description":"Adaptor related protein complex 4 subunit sigma 1","Uniprot":["Q9Y587"],"Chromosome":"14","Position":"31025106-31130996","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"36.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039963"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA039963":"AB_10795240"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.44e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.87e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"9.8","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"10.6","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"14.1","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"5.6","Tissue RNA - colon [nTPM]":"8.6","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"8.7","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"10.2","Tissue RNA - kidney [nTPM]":"7.8","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"10.7","Tissue RNA - pancreas [nTPM]":"7.9","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"6.2","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"11.9","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"6.7","Tissue RNA - skeletal muscle [nTPM]":"12.6","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"18.4","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"6.2","Tissue RNA - vagina [nTPM]":"4.8","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"9.0","Cell RNA - A549 [nTPM]":"12.6","Cell RNA - AF22 [nTPM]":"11.0","Cell RNA - AN3-CA [nTPM]":"3.2","Cell RNA - ASC diff [nTPM]":"4.4","Cell RNA - ASC TERT1 [nTPM]":"7.9","Cell RNA - BEWO [nTPM]":"8.5","Cell RNA - BJ [nTPM]":"6.0","Cell RNA - BJ hTERT+ [nTPM]":"10.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.5","Cell RNA - CACO-2 [nTPM]":"12.2","Cell RNA - CAPAN-2 [nTPM]":"14.5","Cell RNA - Daudi [nTPM]":"10.6","Cell RNA - EFO-21 [nTPM]":"5.5","Cell RNA - fHDF\/TERT166 [nTPM]":"7.3","Cell RNA - GAMG [nTPM]":"7.2","Cell RNA - HaCaT [nTPM]":"9.7","Cell RNA - HAP1 [nTPM]":"7.6","Cell RNA - HBEC3-KT [nTPM]":"9.4","Cell RNA - HBF TERT88 [nTPM]":"15.9","Cell RNA - HDLM-2 [nTPM]":"9.1","Cell RNA - HEK 293 [nTPM]":"4.4","Cell RNA - HEL [nTPM]":"16.4","Cell RNA - HeLa [nTPM]":"5.5","Cell RNA - Hep G2 [nTPM]":"19.0","Cell RNA - HHSteC [nTPM]":"9.5","Cell RNA - HL-60 [nTPM]":"14.1","Cell RNA - HMC-1 [nTPM]":"9.2","Cell RNA - HSkMC [nTPM]":"6.3","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.6","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.4","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"8.4","Cell RNA - Karpas-707 [nTPM]":"7.0","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"12.5","Cell RNA - MOLT-4 [nTPM]":"9.7","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"13.1","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"10.9","Cell RNA - REH [nTPM]":"10.3","Cell RNA - RH-30 [nTPM]":"9.8","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"10.5","Cell RNA - RT4 [nTPM]":"12.4","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"6.1","Cell RNA - SiHa [nTPM]":"10.7","Cell RNA - SK-BR-3 [nTPM]":"5.1","Cell RNA - SK-MEL-30 [nTPM]":"16.3","Cell RNA - SuSa [nTPM]":"7.3","Cell RNA - T-47d [nTPM]":"10.8","Cell RNA - THP-1 [nTPM]":"6.5","Cell RNA - TIME [nTPM]":"8.8","Cell RNA - U-138 MG [nTPM]":"7.3","Cell RNA - U-2 OS [nTPM]":"6.5","Cell RNA - U-2197 [nTPM]":"5.0","Cell RNA - U-251 MG [nTPM]":"5.2","Cell RNA - U-266\/70 [nTPM]":"8.6","Cell RNA - U-266\/84 [nTPM]":"17.0","Cell RNA - U-698 [nTPM]":"15.9","Cell RNA - U-87 MG [nTPM]":"4.2","Cell RNA - U-937 [nTPM]":"4.4","Cell RNA - WM-115 [nTPM]":"5.7","Blood RNA - basophil [nTPM]":"3.4","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"3.3","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"5.8","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"6.6","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"9.8","Brain RNA - basal ganglia [nTPM]":"10.6","Brain RNA - cerebellum [nTPM]":"14.1","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"10.2","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"8.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.1","Single Cell Type RNA - dendritic cells [nTPM]":"7.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.6","Single Cell Type RNA - Early spermatids [nTPM]":"21.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.8","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"7.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"4.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.1","Single Cell Type RNA - Late spermatids [nTPM]":"17.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"6.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"7.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.8","Single Cell Type RNA - Paneth cells [nTPM]":"6.2","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"36.0","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - T-cells [nTPM]":"7.3","Single Cell Type RNA - Theca cells [nTPM]":"8.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.0","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"AP5Z1","Gene synonym":["KIAA0415","SPG48","zeta"],"Ensembl":"ENSG00000242802","Gene description":"Adaptor related protein complex 5 subunit zeta 1","Uniprot":["O43299"],"Chromosome":"7","Position":"4775615-4794397","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NB-4":"15.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035693"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA035693":"AB_10960687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.35e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.8","Tissue RNA - adrenal gland [nTPM]":"18.5","Tissue RNA - amygdala [nTPM]":"7.0","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"7.1","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"12.4","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"13.2","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"13.4","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"5.7","Tissue RNA - kidney [nTPM]":"9.2","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"12.9","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"11.8","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"11.7","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"12.4","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"21.8","Tissue RNA - small intestine [nTPM]":"15.5","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"22.9","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"8.6","Tissue RNA - thalamus [nTPM]":"7.4","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"13.4","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"2.8","Cell RNA - A549 [nTPM]":"4.2","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"2.4","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"4.3","Cell RNA - BJ [nTPM]":"1.3","Cell RNA - BJ hTERT+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"5.2","Cell RNA - CAPAN-2 [nTPM]":"3.5","Cell RNA - Daudi [nTPM]":"1.6","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"5.1","Cell RNA - HaCaT [nTPM]":"5.4","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"1.8","Cell RNA - HEK 293 [nTPM]":"3.5","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"4.5","Cell RNA - Hep G2 [nTPM]":"4.6","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"2.5","Cell RNA - HMC-1 [nTPM]":"5.1","Cell RNA - HSkMC [nTPM]":"2.2","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"2.2","Cell RNA - K-562 [nTPM]":"3.4","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"7.7","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"15.0","Cell RNA - NTERA-2 [nTPM]":"5.9","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"4.3","Cell RNA - REH [nTPM]":"2.9","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"4.8","Cell RNA - RPTEC TERT1 [nTPM]":"1.0","Cell RNA - RT4 [nTPM]":"4.4","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"3.0","Cell RNA - SiHa [nTPM]":"1.8","Cell RNA - SK-BR-3 [nTPM]":"8.7","Cell RNA - SK-MEL-30 [nTPM]":"6.4","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"6.4","Cell RNA - THP-1 [nTPM]":"8.9","Cell RNA - TIME [nTPM]":"3.8","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"4.4","Cell RNA - U-2197 [nTPM]":"6.5","Cell RNA - U-251 MG [nTPM]":"1.7","Cell RNA - U-266\/70 [nTPM]":"8.5","Cell RNA - U-266\/84 [nTPM]":"7.4","Cell RNA - U-698 [nTPM]":"2.3","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"5.6","Cell RNA - WM-115 [nTPM]":"3.6","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"2.8","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"7.0","Brain RNA - basal ganglia [nTPM]":"7.1","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"5.7","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"7.4","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"18.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"6.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - dendritic cells [nTPM]":"20.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"14.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.1","Single Cell Type RNA - Endothelial cells [nTPM]":"11.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"9.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.4","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"14.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"8.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.7","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.3","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"16.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"23.4","Single Cell Type RNA - Muller glia cells [nTPM]":"8.2","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.6","Single Cell Type RNA - Paneth cells [nTPM]":"15.9","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"19.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.5","Single Cell Type RNA - Spermatocytes [nTPM]":"8.1","Single Cell Type RNA - Spermatogonia [nTPM]":"10.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"15.6","Single Cell Type RNA - Theca cells [nTPM]":"12.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"APOA1","Gene synonym":[],"Ensembl":"ENSG00000118137","Gene description":"Apolipoprotein A1","Uniprot":["P02647"],"Chromosome":"11","Position":"116835751-116837622","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":null,"Disease involvement":["Amyloidosis","Atherosclerosis","Cancer-related genes","Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"19248.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Hepatocytes":"27332.1","Proximal enterocytes":"18348.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"48","RNA cancer specific FPKM":{"liver cancer":"4515.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"Hep G2":"3460.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016778","HPA046715"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1450000000000,"Blood concentration - Conc. blood MS [pg\/L]":"110000000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016778":null,"HPA046715":"AB_2679768"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.05e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.67e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.2","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"3.6","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"1709.3","Tissue RNA - endometrium 1 [nTPM]":"3.5","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"67.2","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"19248.5","Tissue RNA - lung [nTPM]":"2.7","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"23.1","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"4.2","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"4053.7","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"9.0","Tissue RNA - stomach 1 [nTPM]":"14.6","Tissue RNA - testis [nTPM]":"384.5","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"3.7","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"15.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"203.4","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"3.1","Cell RNA - EFO-21 [nTPM]":"6.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"3460.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"16.6","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"2.3","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"15.0","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"15.0","Cell RNA - RPMI-8226 [nTPM]":"20.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"2.6","Cell RNA - SCLC-21H [nTPM]":"5.7","Cell RNA - SH-SY5Y [nTPM]":"20.7","Cell RNA - SiHa [nTPM]":"8.9","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"4.9","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"5.5","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"49.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"479.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"5.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"36.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.3","Single Cell Type RNA - Endothelial cells [nTPM]":"50.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"541.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"419.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"458.7","Single Cell Type RNA - Hepatocytes [nTPM]":"27332.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"458.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"681.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.0","Single Cell Type RNA - Late spermatids [nTPM]":"149.7","Single Cell Type RNA - Leydig cells [nTPM]":"22.4","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"458.2","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18348.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.0","Single Cell Type RNA - Spermatocytes [nTPM]":"39.8","Single Cell Type RNA - Spermatogonia [nTPM]":"11.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"35.7","Single Cell Type RNA - Theca cells [nTPM]":"1051.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"175.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"APOE","Gene synonym":["AD2"],"Ensembl":"ENSG00000130203","Gene description":"Apolipoprotein E","Uniprot":["P02649"],"Chromosome":"19","Position":"44905791-44909393","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted secreted proteins"],"Biological process":["Cholesterol metabolism","Host-virus interaction","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":["Heparin-binding"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cancer-related genes","Disease variant","Hyperlipidemia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"3453.9","liver":"6592.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"9363.4","Hofbauer cells":"6072.6","Muller glia cells":"9454.8","Peritubular cells":"4958.2","Proximal tubular cells":"8155.9","Theca cells":"7201.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"3183.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1867.0","CACO-2":"466.1","Hep G2":"935.3","HSkMC":"1374.2","SK-MEL-30":"1956.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008363","HPA065539","HPA068768","CAB069921"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":51800000000,"Blood concentration - Conc. blood MS [pg\/L]":"29000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB008363":"AB_590560","CAB069921":"AB_920623","HPA065539":"AB_2685509","HPA068768":"AB_2686029"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"522.1","Tissue RNA - adrenal gland [nTPM]":"3453.9","Tissue RNA - amygdala [nTPM]":"813.4","Tissue RNA - appendix [nTPM]":"92.8","Tissue RNA - basal ganglia [nTPM]":"1164.2","Tissue RNA - bone marrow [nTPM]":"66.5","Tissue RNA - breast [nTPM]":"325.1","Tissue RNA - cerebellum [nTPM]":"775.0","Tissue RNA - cerebral cortex [nTPM]":"943.2","Tissue RNA - cervix [nTPM]":"271.2","Tissue RNA - choroid plexus [nTPM]":"329.2","Tissue RNA - colon [nTPM]":"130.9","Tissue RNA - duodenum [nTPM]":"40.3","Tissue RNA - endometrium 1 [nTPM]":"81.5","Tissue RNA - epididymis [nTPM]":"20.0","Tissue RNA - esophagus [nTPM]":"37.2","Tissue RNA - fallopian tube [nTPM]":"72.2","Tissue RNA - gallbladder [nTPM]":"100.2","Tissue RNA - heart muscle [nTPM]":"176.3","Tissue RNA - hippocampal formation [nTPM]":"606.1","Tissue RNA - hypothalamus [nTPM]":"841.6","Tissue RNA - kidney [nTPM]":"1066.0","Tissue RNA - liver [nTPM]":"6592.5","Tissue RNA - lung [nTPM]":"258.8","Tissue RNA - lymph node [nTPM]":"352.2","Tissue RNA - medulla oblongata [nTPM]":"1016.0","Tissue RNA - midbrain [nTPM]":"1037.0","Tissue RNA - ovary [nTPM]":"508.2","Tissue RNA - pancreas [nTPM]":"41.9","Tissue RNA - parathyroid gland [nTPM]":"34.5","Tissue RNA - pituitary gland [nTPM]":"110.9","Tissue RNA - placenta [nTPM]":"102.2","Tissue RNA - pons [nTPM]":"1106.9","Tissue RNA - prostate [nTPM]":"45.4","Tissue RNA - rectum [nTPM]":"22.9","Tissue RNA - retina [nTPM]":"87.6","Tissue RNA - salivary gland [nTPM]":"80.5","Tissue RNA - seminal vesicle [nTPM]":"10.8","Tissue RNA - skeletal muscle [nTPM]":"31.1","Tissue RNA - skin 1 [nTPM]":"381.2","Tissue RNA - small intestine [nTPM]":"165.9","Tissue RNA - smooth muscle [nTPM]":"12.6","Tissue RNA - spinal cord [nTPM]":"823.2","Tissue RNA - spleen [nTPM]":"620.3","Tissue RNA - stomach 1 [nTPM]":"83.3","Tissue RNA - testis [nTPM]":"140.5","Tissue RNA - thalamus [nTPM]":"962.6","Tissue RNA - thymus [nTPM]":"57.8","Tissue RNA - thyroid gland [nTPM]":"146.4","Tissue RNA - tongue [nTPM]":"10.4","Tissue RNA - tonsil [nTPM]":"46.1","Tissue RNA - urinary bladder [nTPM]":"93.4","Tissue RNA - vagina [nTPM]":"135.5","Tissue RNA - white matter [nTPM]":"964.4","Cell RNA - A-431 [nTPM]":"3.2","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"1867.0","Cell RNA - ASC TERT1 [nTPM]":"76.3","Cell RNA - BEWO [nTPM]":"69.4","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"466.1","Cell RNA - CAPAN-2 [nTPM]":"2.8","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"9.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"9.1","Cell RNA - HaCaT [nTPM]":"6.4","Cell RNA - HAP1 [nTPM]":"12.6","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"1.7","Cell RNA - HEK 293 [nTPM]":"4.0","Cell RNA - HEL [nTPM]":"3.3","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"935.3","Cell RNA - HHSteC [nTPM]":"192.4","Cell RNA - HL-60 [nTPM]":"6.8","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"1374.2","Cell RNA - hTCEpi [nTPM]":"2.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.8","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"15.6","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"124.9","Cell RNA - Karpas-707 [nTPM]":"2.8","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"243.2","Cell RNA - OE19 [nTPM]":"3.0","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"2.6","Cell RNA - RH-30 [nTPM]":"8.0","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"5.6","Cell RNA - SH-SY5Y [nTPM]":"2.4","Cell RNA - SiHa [nTPM]":"4.5","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"1956.0","Cell RNA - SuSa [nTPM]":"131.6","Cell RNA - T-47d [nTPM]":"165.3","Cell RNA - THP-1 [nTPM]":"52.8","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"13.2","Cell RNA - U-2 OS [nTPM]":"3.1","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"1.6","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"8.6","Cell RNA - U-698 [nTPM]":"3.8","Cell RNA - U-87 MG [nTPM]":"5.9","Cell RNA - U-937 [nTPM]":"4.0","Cell RNA - WM-115 [nTPM]":"2.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"813.4","Brain RNA - basal ganglia [nTPM]":"1164.2","Brain RNA - cerebellum [nTPM]":"775.0","Brain RNA - cerebral cortex [nTPM]":"943.2","Brain RNA - hippocampal formation [nTPM]":"606.1","Brain RNA - hypothalamus [nTPM]":"841.6","Brain RNA - medulla oblongata [nTPM]":"1016.0","Brain RNA - midbrain [nTPM]":"1037.0","Brain RNA - pons [nTPM]":"1106.9","Brain RNA - spinal cord [nTPM]":"823.2","Brain RNA - thalamus [nTPM]":"962.6","Brain RNA - white matter [nTPM]":"964.4","Single Cell Type RNA - Adipocytes [nTPM]":"136.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"444.0","Single Cell Type RNA - B-cells [nTPM]":"66.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"935.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"67.7","Single Cell Type RNA - Bipolar cells [nTPM]":"81.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"86.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"565.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"450.4","Single Cell Type RNA - Club cells [nTPM]":"5.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"228.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.3","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"682.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"73.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"936.6","Single Cell Type RNA - Endothelial cells [nTPM]":"140.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"331.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.8","Single Cell Type RNA - Fibroblasts [nTPM]":"860.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.9","Single Cell Type RNA - granulocytes [nTPM]":"174.4","Single Cell Type RNA - Granulosa cells [nTPM]":"103.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"208.9","Single Cell Type RNA - Hepatocytes [nTPM]":"9363.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"6072.6","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"718.0","Single Cell Type RNA - Langerhans cells [nTPM]":"292.6","Single Cell Type RNA - Late spermatids [nTPM]":"355.3","Single Cell Type RNA - Leydig cells [nTPM]":"2629.4","Single Cell Type RNA - Macrophages [nTPM]":"940.6","Single Cell Type RNA - Melanocytes [nTPM]":"2481.3","Single Cell Type RNA - Microglial cells [nTPM]":"60.9","Single Cell Type RNA - monocytes [nTPM]":"70.3","Single Cell Type RNA - Muller glia cells [nTPM]":"9454.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"4958.2","Single Cell Type RNA - Plasma cells [nTPM]":"7.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8155.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"311.4","Single Cell Type RNA - Sertoli cells [nTPM]":"223.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2958.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"345.5","Single Cell Type RNA - Spermatocytes [nTPM]":"14.8","Single Cell Type RNA - Spermatogonia [nTPM]":"12.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1684.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"74.3","Single Cell Type RNA - T-cells [nTPM]":"60.6","Single Cell Type RNA - Theca cells [nTPM]":"7201.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"4.7"},{"Gene":"APP","Gene synonym":["AD1"],"Ensembl":"ENSG00000142192","Gene description":"Amyloid beta precursor protein","Uniprot":["P05067"],"Chromosome":"21","Position":"25880550-26171128","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Apoptosis","Cell adhesion","Endocytosis","Notch signaling pathway"],"Molecular function":["Heparin-binding","Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Alzheimer disease","Amyloidosis","Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"870.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"38.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"38.1"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000157","HPA001462"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB000157":"AB_323833","HPA001462":"AB_1078185"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.79e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Tissue RNA - adipose tissue [nTPM]":"249.9","Tissue RNA - adrenal gland [nTPM]":"498.0","Tissue RNA - amygdala [nTPM]":"413.0","Tissue RNA - appendix [nTPM]":"157.4","Tissue RNA - basal ganglia [nTPM]":"457.6","Tissue RNA - bone marrow [nTPM]":"134.4","Tissue RNA - breast [nTPM]":"447.5","Tissue RNA - cerebellum [nTPM]":"413.1","Tissue RNA - cerebral cortex [nTPM]":"572.4","Tissue RNA - cervix [nTPM]":"264.2","Tissue RNA - choroid plexus [nTPM]":"396.8","Tissue RNA - colon [nTPM]":"357.2","Tissue RNA - duodenum [nTPM]":"226.4","Tissue RNA - endometrium 1 [nTPM]":"281.1","Tissue RNA - epididymis [nTPM]":"293.3","Tissue RNA - esophagus [nTPM]":"178.6","Tissue RNA - fallopian tube [nTPM]":"308.1","Tissue RNA - gallbladder [nTPM]":"350.8","Tissue RNA - heart muscle [nTPM]":"389.0","Tissue RNA - hippocampal formation [nTPM]":"456.2","Tissue RNA - hypothalamus [nTPM]":"405.3","Tissue RNA - kidney [nTPM]":"532.5","Tissue RNA - liver [nTPM]":"298.2","Tissue RNA - lung [nTPM]":"279.4","Tissue RNA - lymph node [nTPM]":"78.9","Tissue RNA - medulla oblongata [nTPM]":"425.0","Tissue RNA - midbrain [nTPM]":"481.9","Tissue RNA - ovary [nTPM]":"306.2","Tissue RNA - pancreas [nTPM]":"323.5","Tissue RNA - parathyroid gland [nTPM]":"278.6","Tissue RNA - pituitary gland [nTPM]":"155.4","Tissue RNA - placenta [nTPM]":"451.9","Tissue RNA - pons [nTPM]":"448.7","Tissue RNA - prostate [nTPM]":"260.6","Tissue RNA - rectum [nTPM]":"328.5","Tissue RNA - retina [nTPM]":"209.3","Tissue RNA - salivary gland [nTPM]":"270.7","Tissue RNA - seminal vesicle [nTPM]":"343.6","Tissue RNA - skeletal muscle [nTPM]":"107.5","Tissue RNA - skin 1 [nTPM]":"218.6","Tissue RNA - small intestine [nTPM]":"200.3","Tissue RNA - smooth muscle [nTPM]":"379.9","Tissue RNA - spinal cord [nTPM]":"419.7","Tissue RNA - spleen [nTPM]":"154.4","Tissue RNA - stomach 1 [nTPM]":"213.5","Tissue RNA - testis [nTPM]":"165.6","Tissue RNA - thalamus [nTPM]":"426.4","Tissue RNA - thymus [nTPM]":"159.2","Tissue RNA - thyroid gland [nTPM]":"469.9","Tissue RNA - tongue [nTPM]":"176.0","Tissue RNA - tonsil [nTPM]":"78.2","Tissue RNA - urinary bladder [nTPM]":"304.9","Tissue RNA - vagina [nTPM]":"151.7","Tissue RNA - white matter [nTPM]":"523.5","Cell RNA - A-431 [nTPM]":"388.7","Cell RNA - A549 [nTPM]":"489.9","Cell RNA - AF22 [nTPM]":"538.4","Cell RNA - AN3-CA [nTPM]":"448.5","Cell RNA - ASC diff [nTPM]":"707.7","Cell RNA - ASC TERT1 [nTPM]":"869.8","Cell RNA - BEWO [nTPM]":"559.8","Cell RNA - BJ [nTPM]":"757.1","Cell RNA - BJ hTERT+ [nTPM]":"1029.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"386.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"449.3","Cell RNA - CACO-2 [nTPM]":"286.4","Cell RNA - CAPAN-2 [nTPM]":"941.0","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"848.3","Cell RNA - fHDF\/TERT166 [nTPM]":"614.8","Cell RNA - GAMG [nTPM]":"505.1","Cell RNA - HaCaT [nTPM]":"255.6","Cell RNA - HAP1 [nTPM]":"326.4","Cell RNA - HBEC3-KT [nTPM]":"921.6","Cell RNA - HBF TERT88 [nTPM]":"324.4","Cell RNA - HDLM-2 [nTPM]":"14.7","Cell RNA - HEK 293 [nTPM]":"253.1","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"275.6","Cell RNA - Hep G2 [nTPM]":"204.1","Cell RNA - HHSteC [nTPM]":"688.0","Cell RNA - HL-60 [nTPM]":"372.0","Cell RNA - HMC-1 [nTPM]":"19.6","Cell RNA - HSkMC [nTPM]":"790.4","Cell RNA - hTCEpi [nTPM]":"990.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"456.8","Cell RNA - hTERT-HME1 [nTPM]":"823.0","Cell RNA - hTERT-RPE1 [nTPM]":"1584.3","Cell RNA - HUVEC TERT2 [nTPM]":"1750.7","Cell RNA - JURKAT [nTPM]":"158.6","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"39.0","Cell RNA - LHCN-M2 [nTPM]":"614.5","Cell RNA - MCF7 [nTPM]":"433.1","Cell RNA - MOLT-4 [nTPM]":"6.5","Cell RNA - NB-4 [nTPM]":"4.0","Cell RNA - NTERA-2 [nTPM]":"416.2","Cell RNA - OE19 [nTPM]":"644.9","Cell RNA - PC-3 [nTPM]":"418.6","Cell RNA - REH [nTPM]":"241.2","Cell RNA - RH-30 [nTPM]":"505.2","Cell RNA - RPMI-8226 [nTPM]":"325.3","Cell RNA - RPTEC TERT1 [nTPM]":"1283.3","Cell RNA - RT4 [nTPM]":"270.1","Cell RNA - SCLC-21H [nTPM]":"267.3","Cell RNA - SH-SY5Y [nTPM]":"385.6","Cell RNA - SiHa [nTPM]":"824.0","Cell RNA - SK-BR-3 [nTPM]":"549.0","Cell RNA - SK-MEL-30 [nTPM]":"393.4","Cell RNA - SuSa [nTPM]":"720.0","Cell RNA - T-47d [nTPM]":"482.4","Cell RNA - THP-1 [nTPM]":"400.1","Cell RNA - TIME [nTPM]":"1837.1","Cell RNA - U-138 MG [nTPM]":"850.8","Cell RNA - U-2 OS [nTPM]":"350.2","Cell RNA - U-2197 [nTPM]":"310.4","Cell RNA - U-251 MG [nTPM]":"371.6","Cell RNA - U-266\/70 [nTPM]":"232.3","Cell RNA - U-266\/84 [nTPM]":"3.1","Cell RNA - U-698 [nTPM]":"4.8","Cell RNA - U-87 MG [nTPM]":"690.4","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"836.3","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"7.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"5.6","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"38.1","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"413.0","Brain RNA - basal ganglia [nTPM]":"457.6","Brain RNA - cerebellum [nTPM]":"413.1","Brain RNA - cerebral cortex [nTPM]":"572.4","Brain RNA - hippocampal formation [nTPM]":"456.2","Brain RNA - hypothalamus [nTPM]":"405.3","Brain RNA - medulla oblongata [nTPM]":"425.0","Brain RNA - midbrain [nTPM]":"481.9","Brain RNA - pons [nTPM]":"448.7","Brain RNA - spinal cord [nTPM]":"419.7","Brain RNA - thalamus [nTPM]":"426.4","Brain RNA - white matter [nTPM]":"523.5","Single Cell Type RNA - Adipocytes [nTPM]":"330.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"109.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"39.6","Single Cell Type RNA - Astrocytes [nTPM]":"70.5","Single Cell Type RNA - B-cells [nTPM]":"47.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"181.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"215.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"449.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"306.7","Single Cell Type RNA - Bipolar cells [nTPM]":"45.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"280.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"199.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"143.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"296.0","Single Cell Type RNA - Club cells [nTPM]":"214.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"502.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"472.6","Single Cell Type RNA - dendritic cells [nTPM]":"180.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"395.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"56.7","Single Cell Type RNA - Ductal cells [nTPM]":"398.7","Single Cell Type RNA - Early spermatids [nTPM]":"46.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"78.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"162.2","Single Cell Type RNA - Endothelial cells [nTPM]":"416.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"162.6","Single Cell Type RNA - Erythroid cells [nTPM]":"29.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"481.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"180.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"141.2","Single Cell Type RNA - Fibroblasts [nTPM]":"309.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"164.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"110.7","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"100.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"539.7","Single Cell Type RNA - Hepatocytes [nTPM]":"125.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"76.3","Single Cell Type RNA - Horizontal cells [nTPM]":"84.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"525.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"303.1","Single Cell Type RNA - Ionocytes [nTPM]":"256.3","Single Cell Type RNA - Kupffer cells [nTPM]":"61.6","Single Cell Type RNA - Langerhans cells [nTPM]":"79.9","Single Cell Type RNA - Late spermatids [nTPM]":"61.8","Single Cell Type RNA - Leydig cells [nTPM]":"242.6","Single Cell Type RNA - Macrophages [nTPM]":"69.9","Single Cell Type RNA - Melanocytes [nTPM]":"161.9","Single Cell Type RNA - Microglial cells [nTPM]":"189.3","Single Cell Type RNA - monocytes [nTPM]":"89.9","Single Cell Type RNA - Muller glia cells [nTPM]":"329.9","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"423.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"870.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"205.4","Single Cell Type RNA - Paneth cells [nTPM]":"223.1","Single Cell Type RNA - Peritubular cells [nTPM]":"296.8","Single Cell Type RNA - Plasma cells [nTPM]":"24.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"187.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"95.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"165.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"164.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.5","Single Cell Type RNA - Sertoli cells [nTPM]":"118.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"336.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"198.5","Single Cell Type RNA - Spermatocytes [nTPM]":"38.3","Single Cell Type RNA - Spermatogonia [nTPM]":"86.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"85.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"106.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"552.1","Single Cell Type RNA - T-cells [nTPM]":"27.0","Single Cell Type RNA - Theca cells [nTPM]":"111.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"283.5","Single Cell Type RNA - Urothelial cells [nTPM]":"133.6"},{"Gene":"APTX","Gene synonym":["AOA","AOA1","AXA1","EAOH","EOAHA","FLJ20157"],"Ensembl":"ENSG00000137074","Gene description":"Aprataxin","Uniprot":["Q7Z2E3"],"Chromosome":"9","Position":"32886601-33025130","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Hydrolase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064930"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA064930":"AB_2685386"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.01e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"14.8","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"14.8","Tissue RNA - bone marrow [nTPM]":"11.0","Tissue RNA - breast [nTPM]":"10.4","Tissue RNA - cerebellum [nTPM]":"14.8","Tissue RNA - cerebral cortex [nTPM]":"20.2","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"13.9","Tissue RNA - colon [nTPM]":"10.2","Tissue RNA - duodenum [nTPM]":"8.6","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"14.7","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"4.9","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"14.8","Tissue RNA - hypothalamus [nTPM]":"15.0","Tissue RNA - kidney [nTPM]":"13.6","Tissue RNA - liver [nTPM]":"15.6","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"14.7","Tissue RNA - midbrain [nTPM]":"14.6","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"12.1","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"15.0","Tissue RNA - prostate [nTPM]":"9.6","Tissue RNA - rectum [nTPM]":"11.2","Tissue RNA - retina [nTPM]":"8.0","Tissue RNA - salivary gland [nTPM]":"9.0","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"9.8","Tissue RNA - skin 1 [nTPM]":"15.3","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"8.9","Tissue RNA - stomach 1 [nTPM]":"9.7","Tissue RNA - testis [nTPM]":"14.7","Tissue RNA - thalamus [nTPM]":"15.2","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"11.0","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"15.0","Cell RNA - A-431 [nTPM]":"36.2","Cell RNA - A549 [nTPM]":"26.1","Cell RNA - AF22 [nTPM]":"18.4","Cell RNA - AN3-CA [nTPM]":"17.1","Cell RNA - ASC diff [nTPM]":"19.0","Cell RNA - ASC TERT1 [nTPM]":"17.4","Cell RNA - BEWO [nTPM]":"25.6","Cell RNA - BJ [nTPM]":"24.8","Cell RNA - BJ hTERT+ [nTPM]":"26.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.5","Cell RNA - CACO-2 [nTPM]":"35.1","Cell RNA - CAPAN-2 [nTPM]":"12.7","Cell RNA - Daudi [nTPM]":"27.8","Cell RNA - EFO-21 [nTPM]":"14.6","Cell RNA - fHDF\/TERT166 [nTPM]":"21.1","Cell RNA - GAMG [nTPM]":"18.4","Cell RNA - HaCaT [nTPM]":"19.4","Cell RNA - HAP1 [nTPM]":"33.7","Cell RNA - HBEC3-KT [nTPM]":"32.8","Cell RNA - HBF TERT88 [nTPM]":"35.1","Cell RNA - HDLM-2 [nTPM]":"39.2","Cell RNA - HEK 293 [nTPM]":"11.2","Cell RNA - HEL [nTPM]":"17.9","Cell RNA - HeLa [nTPM]":"32.5","Cell RNA - Hep G2 [nTPM]":"37.8","Cell RNA - HHSteC [nTPM]":"24.4","Cell RNA - HL-60 [nTPM]":"29.4","Cell RNA - HMC-1 [nTPM]":"15.1","Cell RNA - HSkMC [nTPM]":"23.8","Cell RNA - hTCEpi [nTPM]":"36.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.5","Cell RNA - hTERT-HME1 [nTPM]":"37.9","Cell RNA - hTERT-RPE1 [nTPM]":"16.9","Cell RNA - HUVEC TERT2 [nTPM]":"26.8","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"27.0","Cell RNA - Karpas-707 [nTPM]":"24.2","Cell RNA - LHCN-M2 [nTPM]":"26.0","Cell RNA - MCF7 [nTPM]":"15.6","Cell RNA - MOLT-4 [nTPM]":"24.4","Cell RNA - NB-4 [nTPM]":"43.2","Cell RNA - NTERA-2 [nTPM]":"33.5","Cell RNA - OE19 [nTPM]":"24.4","Cell RNA - PC-3 [nTPM]":"29.0","Cell RNA - REH [nTPM]":"21.2","Cell RNA - RH-30 [nTPM]":"14.4","Cell RNA - RPMI-8226 [nTPM]":"21.5","Cell RNA - RPTEC TERT1 [nTPM]":"25.2","Cell RNA - RT4 [nTPM]":"21.2","Cell RNA - SCLC-21H [nTPM]":"15.6","Cell RNA - SH-SY5Y [nTPM]":"11.1","Cell RNA - SiHa [nTPM]":"21.4","Cell RNA - SK-BR-3 [nTPM]":"18.0","Cell RNA - SK-MEL-30 [nTPM]":"15.5","Cell RNA - SuSa [nTPM]":"17.9","Cell RNA - T-47d [nTPM]":"23.0","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"17.7","Cell RNA - U-138 MG [nTPM]":"16.2","Cell RNA - U-2 OS [nTPM]":"21.1","Cell RNA - U-2197 [nTPM]":"29.9","Cell RNA - U-251 MG [nTPM]":"25.0","Cell RNA - U-266\/70 [nTPM]":"11.1","Cell RNA - U-266\/84 [nTPM]":"21.2","Cell RNA - U-698 [nTPM]":"27.5","Cell RNA - U-87 MG [nTPM]":"23.4","Cell RNA - U-937 [nTPM]":"23.8","Cell RNA - WM-115 [nTPM]":"13.2","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"14.7","Blood RNA - eosinophil [nTPM]":"13.4","Blood RNA - gdT-cell [nTPM]":"12.2","Blood RNA - intermediate monocyte [nTPM]":"15.6","Blood RNA - MAIT T-cell [nTPM]":"15.2","Blood RNA - memory B-cell [nTPM]":"16.3","Blood RNA - memory CD4 T-cell [nTPM]":"12.8","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"17.6","Blood RNA - naive B-cell [nTPM]":"16.1","Blood RNA - naive CD4 T-cell [nTPM]":"16.0","Blood RNA - naive CD8 T-cell [nTPM]":"12.1","Blood RNA - neutrophil [nTPM]":"5.9","Blood RNA - NK-cell [nTPM]":"23.1","Blood RNA - non-classical monocyte [nTPM]":"21.7","Blood RNA - plasmacytoid DC [nTPM]":"15.2","Blood RNA - T-reg [nTPM]":"17.3","Blood RNA - total PBMC [nTPM]":"16.1","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"14.8","Brain RNA - cerebellum [nTPM]":"14.8","Brain RNA - cerebral cortex [nTPM]":"20.2","Brain RNA - hippocampal formation [nTPM]":"14.8","Brain RNA - hypothalamus [nTPM]":"15.0","Brain RNA - medulla oblongata [nTPM]":"14.7","Brain RNA - midbrain [nTPM]":"14.6","Brain RNA - pons [nTPM]":"15.0","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"15.2","Brain RNA - white matter [nTPM]":"15.0","Single Cell Type RNA - Adipocytes [nTPM]":"14.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.0","Single Cell Type RNA - Astrocytes [nTPM]":"31.3","Single Cell Type RNA - B-cells [nTPM]":"16.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"23.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.7","Single Cell Type RNA - dendritic cells [nTPM]":"15.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"25.3","Single Cell Type RNA - Early spermatids [nTPM]":"55.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"20.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.1","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"17.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"21.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.8","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"14.7","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"48.7","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"15.0","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"19.3","Single Cell Type RNA - Muller glia cells [nTPM]":"18.3","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.9","Single Cell Type RNA - Paneth cells [nTPM]":"6.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"28.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.2","Single Cell Type RNA - Spermatocytes [nTPM]":"42.2","Single Cell Type RNA - Spermatogonia [nTPM]":"26.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"20.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.3","Single Cell Type RNA - Urothelial cells [nTPM]":"23.1"},{"Gene":"AQP4","Gene synonym":["MIWC"],"Ensembl":"ENSG00000171885","Gene description":"Aquaporin 4","Uniprot":["P55087"],"Chromosome":"18","Position":"26852043-26865771","Protein class":["Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"440.5","lung":"114.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"1102.6","Alveolar cells type 2":"342.3","Astrocytes":"487.7","Muller glia cells":"227.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"22","RNA cancer specific FPKM":{"glioma":"223.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"2.4","RPTEC TERT1":"1.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005079","HPA014784","CAB058689"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB005079":"AB_2274338","CAB058689":"AB_2665579","HPA014784":"AB_1844967"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-8"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"272.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"298.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"282.0","Tissue RNA - cerebral cortex [nTPM]":"246.3","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"62.9","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"283.6","Tissue RNA - hypothalamus [nTPM]":"440.5","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"114.8","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"250.5","Tissue RNA - midbrain [nTPM]":"351.2","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"2.2","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"333.3","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"60.2","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"60.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"333.0","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"11.4","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"387.1","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"20.9","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"376.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"272.7","Brain RNA - basal ganglia [nTPM]":"298.7","Brain RNA - cerebellum [nTPM]":"282.0","Brain RNA - cerebral cortex [nTPM]":"246.3","Brain RNA - hippocampal formation [nTPM]":"283.6","Brain RNA - hypothalamus [nTPM]":"440.5","Brain RNA - medulla oblongata [nTPM]":"250.5","Brain RNA - midbrain [nTPM]":"351.2","Brain RNA - pons [nTPM]":"333.3","Brain RNA - spinal cord [nTPM]":"333.0","Brain RNA - thalamus [nTPM]":"387.1","Brain RNA - white matter [nTPM]":"376.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1102.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"342.3","Single Cell Type RNA - Astrocytes [nTPM]":"487.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"76.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"227.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"AR","Gene synonym":["AIS","DHTR","HUMARA","NR3C4","SBMA","SMAX1"],"Ensembl":"ENSG00000169083","Gene description":"Androgen receptor","Uniprot":["P10275"],"Chromosome":"X","Position":"67544021-67730619","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Nuclear receptors","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Neurodegeneration","Pseudohermaphroditism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"38.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"93.7","Granulosa cells":"104.8","Hepatocytes":"269.2","Leydig cells":"77.9","Peritubular cells":"86.5","Skeletal myocytes":"75.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"15.6","prostate cancer":"16.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"13.3","BJ hTERT+":"10.3","HAP1":"14.9","LHCN-M2":"16.1","RH-30":"23.6","T-47d":"10.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000001","HPA004733","CAB065764"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB000001":"AB_2060174","CAB065764":"AB_10620739","HPA004733":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.77e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.03e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"8.7","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"23.6","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"18.6","Tissue RNA - epididymis [nTPM]":"16.1","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"20.7","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"38.2","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"3.5","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"14.6","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"16.5","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"18.2","Tissue RNA - skeletal muscle [nTPM]":"13.9","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"9.5","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"2.1","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"4.8","Cell RNA - AF22 [nTPM]":"13.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"7.3","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"14.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"5.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"3.9","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"4.6","Cell RNA - Karpas-707 [nTPM]":"2.2","Cell RNA - LHCN-M2 [nTPM]":"16.1","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"23.6","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.6","Cell RNA - T-47d [nTPM]":"10.9","Cell RNA - THP-1 [nTPM]":"7.6","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"3.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.5","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"28.4","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"93.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"10.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.5","Single Cell Type RNA - dendritic cells [nTPM]":"14.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"39.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"104.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.0","Single Cell Type RNA - Hepatocytes [nTPM]":"269.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"77.9","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"86.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"75.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"37.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"22.0"},{"Gene":"ARHGEF18","Gene synonym":["KIAA0521","MGC15913","P114-RhoGEF","p114RhoGEF"],"Ensembl":"ENSG00000104880","Gene description":"Rho\/Rac guanine nucleotide exchange factor 18","Uniprot":["Q6ZSZ5"],"Chromosome":"19","Position":"7348937-7472485","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"17.0","Excitatory neurons":"22.2","Inhibitory neurons":"18.0","Microglial cells":"14.0","Oligodendrocyte precursor cells":"18.1","Oligodendrocytes":"30.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042689","HPA049151","HPA071867"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042689":"AB_10794385","HPA049151":"AB_2680654","HPA071867":"AB_2686466"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.21e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.11e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.2","Tissue RNA - adrenal gland [nTPM]":"15.9","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"20.0","Tissue RNA - basal ganglia [nTPM]":"13.3","Tissue RNA - bone marrow [nTPM]":"27.1","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"9.7","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"12.2","Tissue RNA - choroid plexus [nTPM]":"7.0","Tissue RNA - colon [nTPM]":"22.1","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"16.8","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"19.9","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"10.7","Tissue RNA - heart muscle [nTPM]":"7.1","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"8.8","Tissue RNA - kidney [nTPM]":"24.1","Tissue RNA - liver [nTPM]":"13.1","Tissue RNA - lung [nTPM]":"14.6","Tissue RNA - lymph node [nTPM]":"29.8","Tissue RNA - medulla oblongata [nTPM]":"12.1","Tissue RNA - midbrain [nTPM]":"13.0","Tissue RNA - ovary [nTPM]":"10.1","Tissue RNA - pancreas [nTPM]":"21.0","Tissue RNA - parathyroid gland [nTPM]":"11.2","Tissue RNA - pituitary gland [nTPM]":"15.8","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"10.8","Tissue RNA - prostate [nTPM]":"14.2","Tissue RNA - rectum [nTPM]":"7.7","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"11.0","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"5.3","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"31.1","Tissue RNA - smooth muscle [nTPM]":"13.9","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"35.9","Tissue RNA - stomach 1 [nTPM]":"22.6","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"12.2","Tissue RNA - thymus [nTPM]":"33.1","Tissue RNA - thyroid gland [nTPM]":"10.8","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"17.5","Tissue RNA - urinary bladder [nTPM]":"14.0","Tissue RNA - vagina [nTPM]":"12.1","Tissue RNA - white matter [nTPM]":"15.3","Cell RNA - A-431 [nTPM]":"31.2","Cell RNA - A549 [nTPM]":"17.9","Cell RNA - AF22 [nTPM]":"10.2","Cell RNA - AN3-CA [nTPM]":"13.9","Cell RNA - ASC diff [nTPM]":"9.4","Cell RNA - ASC TERT1 [nTPM]":"7.8","Cell RNA - BEWO [nTPM]":"30.8","Cell RNA - BJ [nTPM]":"13.4","Cell RNA - BJ hTERT+ [nTPM]":"12.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.8","Cell RNA - CACO-2 [nTPM]":"24.5","Cell RNA - CAPAN-2 [nTPM]":"17.4","Cell RNA - Daudi [nTPM]":"62.9","Cell RNA - EFO-21 [nTPM]":"29.4","Cell RNA - fHDF\/TERT166 [nTPM]":"15.2","Cell RNA - GAMG [nTPM]":"15.3","Cell RNA - HaCaT [nTPM]":"24.6","Cell RNA - HAP1 [nTPM]":"12.7","Cell RNA - HBEC3-KT [nTPM]":"29.7","Cell RNA - HBF TERT88 [nTPM]":"11.8","Cell RNA - HDLM-2 [nTPM]":"37.6","Cell RNA - HEK 293 [nTPM]":"16.1","Cell RNA - HEL [nTPM]":"15.5","Cell RNA - HeLa [nTPM]":"11.7","Cell RNA - Hep G2 [nTPM]":"16.4","Cell RNA - HHSteC [nTPM]":"22.1","Cell RNA - HL-60 [nTPM]":"31.2","Cell RNA - HMC-1 [nTPM]":"30.4","Cell RNA - HSkMC [nTPM]":"12.8","Cell RNA - hTCEpi [nTPM]":"20.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.7","Cell RNA - hTERT-HME1 [nTPM]":"16.3","Cell RNA - hTERT-RPE1 [nTPM]":"10.1","Cell RNA - HUVEC TERT2 [nTPM]":"11.2","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"13.4","Cell RNA - Karpas-707 [nTPM]":"14.7","Cell RNA - LHCN-M2 [nTPM]":"21.3","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"36.0","Cell RNA - NB-4 [nTPM]":"26.8","Cell RNA - NTERA-2 [nTPM]":"16.0","Cell RNA - OE19 [nTPM]":"16.9","Cell RNA - PC-3 [nTPM]":"29.2","Cell RNA - REH [nTPM]":"42.2","Cell RNA - RH-30 [nTPM]":"17.6","Cell RNA - RPMI-8226 [nTPM]":"17.2","Cell RNA - RPTEC TERT1 [nTPM]":"9.0","Cell RNA - RT4 [nTPM]":"34.6","Cell RNA - SCLC-21H [nTPM]":"9.8","Cell RNA - SH-SY5Y [nTPM]":"13.7","Cell RNA - SiHa [nTPM]":"16.4","Cell RNA - SK-BR-3 [nTPM]":"16.1","Cell RNA - SK-MEL-30 [nTPM]":"18.8","Cell RNA - SuSa [nTPM]":"9.6","Cell RNA - T-47d [nTPM]":"17.4","Cell RNA - THP-1 [nTPM]":"36.4","Cell RNA - TIME [nTPM]":"21.9","Cell RNA - U-138 MG [nTPM]":"16.8","Cell RNA - U-2 OS [nTPM]":"20.1","Cell RNA - U-2197 [nTPM]":"25.9","Cell RNA - U-251 MG [nTPM]":"17.2","Cell RNA - U-266\/70 [nTPM]":"35.6","Cell RNA - U-266\/84 [nTPM]":"23.2","Cell RNA - U-698 [nTPM]":"40.2","Cell RNA - U-87 MG [nTPM]":"16.7","Cell RNA - U-937 [nTPM]":"27.5","Cell RNA - WM-115 [nTPM]":"15.1","Blood RNA - basophil [nTPM]":"6.4","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"23.0","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"4.5","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"8.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.3","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"12.4","Blood RNA - naive CD4 T-cell [nTPM]":"5.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"12.5","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"6.9","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"3.9","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"13.3","Brain RNA - cerebellum [nTPM]":"9.7","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"8.8","Brain RNA - medulla oblongata [nTPM]":"12.1","Brain RNA - midbrain [nTPM]":"13.0","Brain RNA - pons [nTPM]":"10.8","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"12.2","Brain RNA - white matter [nTPM]":"15.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"ARHGEF9","Gene synonym":["KIAA0424","PEM-2"],"Ensembl":"ENSG00000131089","Gene description":"Cdc42 guanine nucleotide exchange factor 9","Uniprot":["O43307"],"Chromosome":"X","Position":"63634967-63809274","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"88.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"184.3","Cone photoreceptor cells":"233.5","Rod photoreceptor cells":"320.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"48.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035419","HPA055291"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035419":"AB_10669859","HPA055291":"AB_2682774"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.02e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.7","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"32.6","Tissue RNA - appendix [nTPM]":"6.4","Tissue RNA - basal ganglia [nTPM]":"39.3","Tissue RNA - bone marrow [nTPM]":"4.1","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"51.0","Tissue RNA - cervix [nTPM]":"8.4","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"13.6","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"11.2","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"35.9","Tissue RNA - hippocampal formation [nTPM]":"46.2","Tissue RNA - hypothalamus [nTPM]":"36.6","Tissue RNA - kidney [nTPM]":"13.2","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"13.1","Tissue RNA - midbrain [nTPM]":"14.3","Tissue RNA - ovary [nTPM]":"16.2","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"15.0","Tissue RNA - pituitary gland [nTPM]":"15.7","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"14.3","Tissue RNA - prostate [nTPM]":"13.8","Tissue RNA - rectum [nTPM]":"14.3","Tissue RNA - retina [nTPM]":"88.1","Tissue RNA - salivary gland [nTPM]":"6.3","Tissue RNA - seminal vesicle [nTPM]":"14.6","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"17.2","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"6.9","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"26.7","Tissue RNA - thymus [nTPM]":"9.5","Tissue RNA - thyroid gland [nTPM]":"8.2","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"7.3","Tissue RNA - urinary bladder [nTPM]":"14.3","Tissue RNA - vagina [nTPM]":"6.5","Tissue RNA - white matter [nTPM]":"27.2","Cell RNA - A-431 [nTPM]":"6.3","Cell RNA - A549 [nTPM]":"9.7","Cell RNA - AF22 [nTPM]":"20.2","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"7.6","Cell RNA - ASC TERT1 [nTPM]":"11.1","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"12.3","Cell RNA - BJ hTERT+ [nTPM]":"11.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.8","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"6.8","Cell RNA - Daudi [nTPM]":"14.1","Cell RNA - EFO-21 [nTPM]":"8.7","Cell RNA - fHDF\/TERT166 [nTPM]":"8.0","Cell RNA - GAMG [nTPM]":"10.8","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"8.4","Cell RNA - HBEC3-KT [nTPM]":"14.5","Cell RNA - HBF TERT88 [nTPM]":"15.1","Cell RNA - HDLM-2 [nTPM]":"18.5","Cell RNA - HEK 293 [nTPM]":"6.6","Cell RNA - HEL [nTPM]":"13.7","Cell RNA - HeLa [nTPM]":"4.5","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"4.5","Cell RNA - HL-60 [nTPM]":"6.7","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"12.2","Cell RNA - hTCEpi [nTPM]":"6.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.9","Cell RNA - hTERT-HME1 [nTPM]":"18.5","Cell RNA - hTERT-RPE1 [nTPM]":"11.9","Cell RNA - HUVEC TERT2 [nTPM]":"7.1","Cell RNA - JURKAT [nTPM]":"14.8","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"20.8","Cell RNA - LHCN-M2 [nTPM]":"14.0","Cell RNA - MCF7 [nTPM]":"10.0","Cell RNA - MOLT-4 [nTPM]":"12.6","Cell RNA - NB-4 [nTPM]":"3.3","Cell RNA - NTERA-2 [nTPM]":"16.4","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"12.1","Cell RNA - REH [nTPM]":"22.9","Cell RNA - RH-30 [nTPM]":"48.2","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"7.8","Cell RNA - RT4 [nTPM]":"6.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"5.6","Cell RNA - SK-BR-3 [nTPM]":"9.8","Cell RNA - SK-MEL-30 [nTPM]":"6.7","Cell RNA - SuSa [nTPM]":"8.4","Cell RNA - T-47d [nTPM]":"7.5","Cell RNA - THP-1 [nTPM]":"8.9","Cell RNA - TIME [nTPM]":"3.4","Cell RNA - U-138 MG [nTPM]":"7.1","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"34.6","Cell RNA - U-251 MG [nTPM]":"5.1","Cell RNA - U-266\/70 [nTPM]":"7.8","Cell RNA - U-266\/84 [nTPM]":"6.5","Cell RNA - U-698 [nTPM]":"10.2","Cell RNA - U-87 MG [nTPM]":"8.7","Cell RNA - U-937 [nTPM]":"10.7","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"3.1","Blood RNA - myeloid DC [nTPM]":"2.2","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.9","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"8.4","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"32.6","Brain RNA - basal ganglia [nTPM]":"39.3","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"51.0","Brain RNA - hippocampal formation [nTPM]":"46.2","Brain RNA - hypothalamus [nTPM]":"36.6","Brain RNA - medulla oblongata [nTPM]":"13.1","Brain RNA - midbrain [nTPM]":"14.3","Brain RNA - pons [nTPM]":"14.3","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"26.7","Brain RNA - white matter [nTPM]":"27.2","Single Cell Type RNA - Adipocytes [nTPM]":"9.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.4","Single Cell Type RNA - Astrocytes [nTPM]":"59.4","Single Cell Type RNA - B-cells [nTPM]":"20.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"184.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"45.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"233.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.0","Single Cell Type RNA - dendritic cells [nTPM]":"19.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.8","Single Cell Type RNA - Endothelial cells [nTPM]":"10.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.9","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"105.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"11.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.0","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"20.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.5","Single Cell Type RNA - Horizontal cells [nTPM]":"82.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"90.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"8.2","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"3.8","Single Cell Type RNA - Muller glia cells [nTPM]":"29.9","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"89.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"50.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.9","Single Cell Type RNA - Paneth cells [nTPM]":"14.5","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"320.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"21.8","Single Cell Type RNA - Theca cells [nTPM]":"39.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.8","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"ARL2BP","Gene synonym":["BART","BART1","RP66"],"Ensembl":"ENSG00000102931","Gene description":"ADP ribosylation factor like GTPase 2 binding protein","Uniprot":["Q9Y2Y0"],"Chromosome":"16","Position":"57245259-57253635","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"264.6","Late spermatids":"503.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043066","HPA048440"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043066":"AB_2678302","HPA048440":"AB_2680393"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.06e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.5","Tissue RNA - adrenal gland [nTPM]":"42.6","Tissue RNA - amygdala [nTPM]":"49.8","Tissue RNA - appendix [nTPM]":"30.1","Tissue RNA - basal ganglia [nTPM]":"51.6","Tissue RNA - bone marrow [nTPM]":"35.7","Tissue RNA - breast [nTPM]":"37.4","Tissue RNA - cerebellum [nTPM]":"51.1","Tissue RNA - cerebral cortex [nTPM]":"58.1","Tissue RNA - cervix [nTPM]":"35.5","Tissue RNA - choroid plexus [nTPM]":"51.9","Tissue RNA - colon [nTPM]":"36.0","Tissue RNA - duodenum [nTPM]":"20.8","Tissue RNA - endometrium 1 [nTPM]":"45.0","Tissue RNA - epididymis [nTPM]":"34.8","Tissue RNA - esophagus [nTPM]":"49.6","Tissue RNA - fallopian tube [nTPM]":"44.1","Tissue RNA - gallbladder [nTPM]":"36.2","Tissue RNA - heart muscle [nTPM]":"54.4","Tissue RNA - hippocampal formation [nTPM]":"51.5","Tissue RNA - hypothalamus [nTPM]":"52.2","Tissue RNA - kidney [nTPM]":"44.0","Tissue RNA - liver [nTPM]":"32.7","Tissue RNA - lung [nTPM]":"44.5","Tissue RNA - lymph node [nTPM]":"37.7","Tissue RNA - medulla oblongata [nTPM]":"50.1","Tissue RNA - midbrain [nTPM]":"51.9","Tissue RNA - ovary [nTPM]":"50.6","Tissue RNA - pancreas [nTPM]":"29.6","Tissue RNA - parathyroid gland [nTPM]":"48.0","Tissue RNA - pituitary gland [nTPM]":"27.6","Tissue RNA - placenta [nTPM]":"37.4","Tissue RNA - pons [nTPM]":"51.6","Tissue RNA - prostate [nTPM]":"34.9","Tissue RNA - rectum [nTPM]":"36.0","Tissue RNA - retina [nTPM]":"37.2","Tissue RNA - salivary gland [nTPM]":"25.4","Tissue RNA - seminal vesicle [nTPM]":"46.0","Tissue RNA - skeletal muscle [nTPM]":"31.8","Tissue RNA - skin 1 [nTPM]":"31.3","Tissue RNA - small intestine [nTPM]":"24.8","Tissue RNA - smooth muscle [nTPM]":"59.3","Tissue RNA - spinal cord [nTPM]":"51.1","Tissue RNA - spleen [nTPM]":"49.4","Tissue RNA - stomach 1 [nTPM]":"27.5","Tissue RNA - testis [nTPM]":"57.1","Tissue RNA - thalamus [nTPM]":"51.6","Tissue RNA - thymus [nTPM]":"44.8","Tissue RNA - thyroid gland [nTPM]":"29.9","Tissue RNA - tongue [nTPM]":"46.1","Tissue RNA - tonsil [nTPM]":"46.3","Tissue RNA - urinary bladder [nTPM]":"39.9","Tissue RNA - vagina [nTPM]":"29.9","Tissue RNA - white matter [nTPM]":"52.1","Cell RNA - A-431 [nTPM]":"74.2","Cell RNA - A549 [nTPM]":"49.4","Cell RNA - AF22 [nTPM]":"93.3","Cell RNA - AN3-CA [nTPM]":"48.7","Cell RNA - ASC diff [nTPM]":"82.6","Cell RNA - ASC TERT1 [nTPM]":"106.0","Cell RNA - BEWO [nTPM]":"23.2","Cell RNA - BJ [nTPM]":"91.2","Cell RNA - BJ hTERT+ [nTPM]":"105.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"104.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"65.9","Cell RNA - CACO-2 [nTPM]":"37.4","Cell RNA - CAPAN-2 [nTPM]":"28.9","Cell RNA - Daudi [nTPM]":"61.9","Cell RNA - EFO-21 [nTPM]":"104.0","Cell RNA - fHDF\/TERT166 [nTPM]":"126.3","Cell RNA - GAMG [nTPM]":"48.8","Cell RNA - HaCaT [nTPM]":"48.5","Cell RNA - HAP1 [nTPM]":"60.3","Cell RNA - HBEC3-KT [nTPM]":"74.0","Cell RNA - HBF TERT88 [nTPM]":"97.8","Cell RNA - HDLM-2 [nTPM]":"28.5","Cell RNA - HEK 293 [nTPM]":"57.8","Cell RNA - HEL [nTPM]":"54.9","Cell RNA - HeLa [nTPM]":"36.3","Cell RNA - Hep G2 [nTPM]":"64.2","Cell RNA - HHSteC [nTPM]":"112.3","Cell RNA - HL-60 [nTPM]":"50.8","Cell RNA - HMC-1 [nTPM]":"113.6","Cell RNA - HSkMC [nTPM]":"91.6","Cell RNA - hTCEpi [nTPM]":"94.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"75.4","Cell RNA - hTERT-HME1 [nTPM]":"103.3","Cell RNA - hTERT-RPE1 [nTPM]":"77.4","Cell RNA - HUVEC TERT2 [nTPM]":"127.5","Cell RNA - JURKAT [nTPM]":"46.7","Cell RNA - K-562 [nTPM]":"42.5","Cell RNA - Karpas-707 [nTPM]":"23.3","Cell RNA - LHCN-M2 [nTPM]":"73.0","Cell RNA - MCF7 [nTPM]":"28.7","Cell RNA - MOLT-4 [nTPM]":"52.3","Cell RNA - NB-4 [nTPM]":"63.9","Cell RNA - NTERA-2 [nTPM]":"32.7","Cell RNA - OE19 [nTPM]":"25.7","Cell RNA - PC-3 [nTPM]":"98.7","Cell RNA - REH [nTPM]":"71.3","Cell RNA - RH-30 [nTPM]":"91.7","Cell RNA - RPMI-8226 [nTPM]":"120.8","Cell RNA - RPTEC TERT1 [nTPM]":"113.8","Cell RNA - RT4 [nTPM]":"26.4","Cell RNA - SCLC-21H [nTPM]":"29.2","Cell RNA - SH-SY5Y [nTPM]":"61.1","Cell RNA - SiHa [nTPM]":"140.1","Cell RNA - SK-BR-3 [nTPM]":"66.1","Cell RNA - SK-MEL-30 [nTPM]":"82.8","Cell RNA - SuSa [nTPM]":"58.1","Cell RNA - T-47d [nTPM]":"48.8","Cell RNA - THP-1 [nTPM]":"66.6","Cell RNA - TIME [nTPM]":"114.6","Cell RNA - U-138 MG [nTPM]":"61.2","Cell RNA - U-2 OS [nTPM]":"37.8","Cell RNA - U-2197 [nTPM]":"53.3","Cell RNA - U-251 MG [nTPM]":"70.8","Cell RNA - U-266\/70 [nTPM]":"58.8","Cell RNA - U-266\/84 [nTPM]":"49.6","Cell RNA - U-698 [nTPM]":"58.9","Cell RNA - U-87 MG [nTPM]":"79.8","Cell RNA - U-937 [nTPM]":"33.2","Cell RNA - WM-115 [nTPM]":"60.2","Blood RNA - basophil [nTPM]":"35.5","Blood RNA - classical monocyte [nTPM]":"46.1","Blood RNA - eosinophil [nTPM]":"27.3","Blood RNA - gdT-cell [nTPM]":"40.5","Blood RNA - intermediate monocyte [nTPM]":"45.3","Blood RNA - MAIT T-cell [nTPM]":"42.3","Blood RNA - memory B-cell [nTPM]":"37.6","Blood RNA - memory CD4 T-cell [nTPM]":"36.7","Blood RNA - memory CD8 T-cell [nTPM]":"44.1","Blood RNA - myeloid DC [nTPM]":"56.5","Blood RNA - naive B-cell [nTPM]":"29.8","Blood RNA - naive CD4 T-cell [nTPM]":"49.5","Blood RNA - naive CD8 T-cell [nTPM]":"42.0","Blood RNA - neutrophil [nTPM]":"7.6","Blood RNA - NK-cell [nTPM]":"63.6","Blood RNA - non-classical monocyte [nTPM]":"51.3","Blood RNA - plasmacytoid DC [nTPM]":"16.3","Blood RNA - T-reg [nTPM]":"33.7","Blood RNA - total PBMC [nTPM]":"55.1","Brain RNA - amygdala [nTPM]":"49.8","Brain RNA - basal ganglia [nTPM]":"51.6","Brain RNA - cerebellum [nTPM]":"51.1","Brain RNA - cerebral cortex [nTPM]":"58.1","Brain RNA - hippocampal formation [nTPM]":"51.5","Brain RNA - hypothalamus [nTPM]":"52.2","Brain RNA - medulla oblongata [nTPM]":"50.1","Brain RNA - midbrain [nTPM]":"51.9","Brain RNA - pons [nTPM]":"51.6","Brain RNA - spinal cord [nTPM]":"51.1","Brain RNA - thalamus [nTPM]":"51.6","Brain RNA - white matter [nTPM]":"52.1","Single Cell Type RNA - Adipocytes [nTPM]":"60.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.4","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"47.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"57.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.7","Single Cell Type RNA - Bipolar cells [nTPM]":"44.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"28.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"51.0","Single Cell Type RNA - dendritic cells [nTPM]":"50.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"76.3","Single Cell Type RNA - Ductal cells [nTPM]":"46.2","Single Cell Type RNA - Early spermatids [nTPM]":"264.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"49.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"57.8","Single Cell Type RNA - Endothelial cells [nTPM]":"63.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.4","Single Cell Type RNA - Erythroid cells [nTPM]":"105.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"58.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.2","Single Cell Type RNA - Fibroblasts [nTPM]":"66.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"58.7","Single Cell Type RNA - granulocytes [nTPM]":"74.3","Single Cell Type RNA - Granulosa cells [nTPM]":"105.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"62.8","Single Cell Type RNA - Hepatocytes [nTPM]":"34.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"63.3","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.5","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"52.8","Single Cell Type RNA - Langerhans cells [nTPM]":"36.5","Single Cell Type RNA - Late spermatids [nTPM]":"503.7","Single Cell Type RNA - Leydig cells [nTPM]":"82.3","Single Cell Type RNA - Macrophages [nTPM]":"42.2","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"71.2","Single Cell Type RNA - Muller glia cells [nTPM]":"66.0","Single Cell Type RNA - NK-cells [nTPM]":"66.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"42.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.6","Single Cell Type RNA - Paneth cells [nTPM]":"18.5","Single Cell Type RNA - Peritubular cells [nTPM]":"109.1","Single Cell Type RNA - Plasma cells [nTPM]":"50.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"65.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.5","Single Cell Type RNA - Spermatocytes [nTPM]":"122.2","Single Cell Type RNA - Spermatogonia [nTPM]":"51.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"66.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"37.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.3","Single Cell Type RNA - T-cells [nTPM]":"60.8","Single Cell Type RNA - Theca cells [nTPM]":"170.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.6","Single Cell Type RNA - Urothelial cells [nTPM]":"22.6"},{"Gene":"ARL3","Gene synonym":["ARFL3"],"Ensembl":"ENSG00000138175","Gene description":"ADP ribosylation factor like GTPase 3","Uniprot":["P36405"],"Chromosome":"10","Position":"102673731-102714397","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"96.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"289.1","Rod photoreceptor cells":"318.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036292","HPA063596"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Centrosome"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA036292":"AB_10673618","HPA063596":"AB_2685053"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.71e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.1","Tissue RNA - adrenal gland [nTPM]":"8.9","Tissue RNA - amygdala [nTPM]":"20.2","Tissue RNA - appendix [nTPM]":"4.2","Tissue RNA - basal ganglia [nTPM]":"21.3","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"20.8","Tissue RNA - cerebral cortex [nTPM]":"25.1","Tissue RNA - cervix [nTPM]":"12.4","Tissue RNA - choroid plexus [nTPM]":"19.1","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"4.2","Tissue RNA - endometrium 1 [nTPM]":"11.5","Tissue RNA - epididymis [nTPM]":"10.6","Tissue RNA - esophagus [nTPM]":"4.6","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"13.5","Tissue RNA - hippocampal formation [nTPM]":"20.8","Tissue RNA - hypothalamus [nTPM]":"19.5","Tissue RNA - kidney [nTPM]":"15.4","Tissue RNA - liver [nTPM]":"5.2","Tissue RNA - lung [nTPM]":"8.3","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"19.3","Tissue RNA - midbrain [nTPM]":"19.1","Tissue RNA - ovary [nTPM]":"16.8","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"19.8","Tissue RNA - pituitary gland [nTPM]":"21.0","Tissue RNA - placenta [nTPM]":"4.9","Tissue RNA - pons [nTPM]":"19.7","Tissue RNA - prostate [nTPM]":"8.7","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"96.3","Tissue RNA - salivary gland [nTPM]":"6.3","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"5.6","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"6.1","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"18.5","Tissue RNA - spleen [nTPM]":"4.5","Tissue RNA - stomach 1 [nTPM]":"8.8","Tissue RNA - testis [nTPM]":"11.0","Tissue RNA - thalamus [nTPM]":"20.5","Tissue RNA - thymus [nTPM]":"5.7","Tissue RNA - thyroid gland [nTPM]":"11.4","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"8.3","Tissue RNA - white matter [nTPM]":"19.5","Cell RNA - A-431 [nTPM]":"14.7","Cell RNA - A549 [nTPM]":"25.0","Cell RNA - AF22 [nTPM]":"33.6","Cell RNA - AN3-CA [nTPM]":"24.7","Cell RNA - ASC diff [nTPM]":"15.2","Cell RNA - ASC TERT1 [nTPM]":"22.7","Cell RNA - BEWO [nTPM]":"5.9","Cell RNA - BJ [nTPM]":"11.4","Cell RNA - BJ hTERT+ [nTPM]":"17.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.7","Cell RNA - CACO-2 [nTPM]":"8.7","Cell RNA - CAPAN-2 [nTPM]":"7.4","Cell RNA - Daudi [nTPM]":"6.1","Cell RNA - EFO-21 [nTPM]":"10.8","Cell RNA - fHDF\/TERT166 [nTPM]":"18.5","Cell RNA - GAMG [nTPM]":"16.4","Cell RNA - HaCaT [nTPM]":"10.7","Cell RNA - HAP1 [nTPM]":"12.7","Cell RNA - HBEC3-KT [nTPM]":"15.3","Cell RNA - HBF TERT88 [nTPM]":"16.9","Cell RNA - HDLM-2 [nTPM]":"16.1","Cell RNA - HEK 293 [nTPM]":"13.4","Cell RNA - HEL [nTPM]":"9.9","Cell RNA - HeLa [nTPM]":"16.9","Cell RNA - Hep G2 [nTPM]":"8.3","Cell RNA - HHSteC [nTPM]":"16.4","Cell RNA - HL-60 [nTPM]":"4.6","Cell RNA - HMC-1 [nTPM]":"9.5","Cell RNA - HSkMC [nTPM]":"11.5","Cell RNA - hTCEpi [nTPM]":"12.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.8","Cell RNA - hTERT-HME1 [nTPM]":"11.0","Cell RNA - hTERT-RPE1 [nTPM]":"36.1","Cell RNA - HUVEC TERT2 [nTPM]":"15.8","Cell RNA - JURKAT [nTPM]":"12.0","Cell RNA - K-562 [nTPM]":"4.5","Cell RNA - Karpas-707 [nTPM]":"6.0","Cell RNA - LHCN-M2 [nTPM]":"23.0","Cell RNA - MCF7 [nTPM]":"15.1","Cell RNA - MOLT-4 [nTPM]":"9.5","Cell RNA - NB-4 [nTPM]":"7.3","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"9.2","Cell RNA - PC-3 [nTPM]":"9.8","Cell RNA - REH [nTPM]":"7.9","Cell RNA - RH-30 [nTPM]":"24.8","Cell RNA - RPMI-8226 [nTPM]":"5.4","Cell RNA - RPTEC TERT1 [nTPM]":"18.1","Cell RNA - RT4 [nTPM]":"7.7","Cell RNA - SCLC-21H [nTPM]":"11.8","Cell RNA - SH-SY5Y [nTPM]":"25.7","Cell RNA - SiHa [nTPM]":"8.7","Cell RNA - SK-BR-3 [nTPM]":"1.8","Cell RNA - SK-MEL-30 [nTPM]":"14.1","Cell RNA - SuSa [nTPM]":"18.5","Cell RNA - T-47d [nTPM]":"45.1","Cell RNA - THP-1 [nTPM]":"4.6","Cell RNA - TIME [nTPM]":"9.1","Cell RNA - U-138 MG [nTPM]":"9.2","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"18.9","Cell RNA - U-251 MG [nTPM]":"16.0","Cell RNA - U-266\/70 [nTPM]":"4.2","Cell RNA - U-266\/84 [nTPM]":"8.9","Cell RNA - U-698 [nTPM]":"11.3","Cell RNA - U-87 MG [nTPM]":"24.4","Cell RNA - U-937 [nTPM]":"13.6","Cell RNA - WM-115 [nTPM]":"8.1","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"7.2","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"6.1","Blood RNA - MAIT T-cell [nTPM]":"9.4","Blood RNA - memory B-cell [nTPM]":"4.5","Blood RNA - memory CD4 T-cell [nTPM]":"6.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.5","Blood RNA - myeloid DC [nTPM]":"7.1","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.7","Blood RNA - neutrophil [nTPM]":"13.4","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"5.4","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"4.9","Blood RNA - total PBMC [nTPM]":"5.4","Brain RNA - amygdala [nTPM]":"20.2","Brain RNA - basal ganglia [nTPM]":"21.3","Brain RNA - cerebellum [nTPM]":"20.8","Brain RNA - cerebral cortex [nTPM]":"25.1","Brain RNA - hippocampal formation [nTPM]":"20.8","Brain RNA - hypothalamus [nTPM]":"19.5","Brain RNA - medulla oblongata [nTPM]":"19.3","Brain RNA - midbrain [nTPM]":"19.1","Brain RNA - pons [nTPM]":"19.7","Brain RNA - spinal cord [nTPM]":"18.5","Brain RNA - thalamus [nTPM]":"20.5","Brain RNA - white matter [nTPM]":"19.5","Single Cell Type RNA - Adipocytes [nTPM]":"46.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"39.3","Single Cell Type RNA - Astrocytes [nTPM]":"47.7","Single Cell Type RNA - B-cells [nTPM]":"16.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"70.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"144.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"167.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"57.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"135.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"85.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"116.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"45.5","Single Cell Type RNA - dendritic cells [nTPM]":"12.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"234.8","Single Cell Type RNA - Ductal cells [nTPM]":"70.7","Single Cell Type RNA - Early spermatids [nTPM]":"46.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"250.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"85.2","Single Cell Type RNA - Endothelial cells [nTPM]":"41.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"74.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.8","Single Cell Type RNA - Fibroblasts [nTPM]":"61.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"84.6","Single Cell Type RNA - granulocytes [nTPM]":"33.0","Single Cell Type RNA - Granulosa cells [nTPM]":"94.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.9","Single Cell Type RNA - Hepatocytes [nTPM]":"25.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"64.7","Single Cell Type RNA - Horizontal cells [nTPM]":"97.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.6","Single Cell Type RNA - Ionocytes [nTPM]":"73.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.4","Single Cell Type RNA - Langerhans cells [nTPM]":"33.6","Single Cell Type RNA - Late spermatids [nTPM]":"25.8","Single Cell Type RNA - Leydig cells [nTPM]":"60.6","Single Cell Type RNA - Macrophages [nTPM]":"26.8","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"67.3","Single Cell Type RNA - Muller glia cells [nTPM]":"289.1","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.1","Single Cell Type RNA - Paneth cells [nTPM]":"13.5","Single Cell Type RNA - Peritubular cells [nTPM]":"104.2","Single Cell Type RNA - Plasma cells [nTPM]":"18.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"54.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"225.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"268.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"318.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"50.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"122.0","Single Cell Type RNA - Spermatocytes [nTPM]":"145.6","Single Cell Type RNA - Spermatogonia [nTPM]":"43.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.3","Single Cell Type RNA - T-cells [nTPM]":"20.8","Single Cell Type RNA - Theca cells [nTPM]":"58.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.4","Single Cell Type RNA - Urothelial cells [nTPM]":"50.5"},{"Gene":"ARL6","Gene synonym":["BBS3","RP55"],"Ensembl":"ENSG00000113966","Gene description":"ADP ribosylation factor like GTPase 6","Uniprot":["Q9H0F7"],"Chromosome":"3","Position":"97764521-97801229","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Protein transport","Sensory transduction","Transport","Vision"],"Molecular function":null,"Disease involvement":["Bardet-Biedl syndrome","Ciliopathy","Disease variant","Mental retardation","Obesity","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"46.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"55.0","Inhibitory neurons":"51.5","Rod photoreceptor cells":"57.4","Spermatocytes":"39.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"26.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019361"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA019361":"AB_1845028"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.53e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.6","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"3.3","Tissue RNA - cerebellum [nTPM]":"4.2","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"3.4","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"3.6","Tissue RNA - hippocampal formation [nTPM]":"5.7","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"3.5","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"3.5","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"12.8","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"3.9","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"46.3","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"3.1","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"3.9","Tissue RNA - spleen [nTPM]":"3.0","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"5.5","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"3.2","Tissue RNA - vagina [nTPM]":"2.1","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"10.1","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"4.9","Cell RNA - AN3-CA [nTPM]":"4.1","Cell RNA - ASC diff [nTPM]":"11.5","Cell RNA - ASC TERT1 [nTPM]":"7.6","Cell RNA - BEWO [nTPM]":"1.3","Cell RNA - BJ [nTPM]":"6.2","Cell RNA - BJ hTERT+ [nTPM]":"5.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.7","Cell RNA - CACO-2 [nTPM]":"2.2","Cell RNA - CAPAN-2 [nTPM]":"3.6","Cell RNA - Daudi [nTPM]":"5.8","Cell RNA - EFO-21 [nTPM]":"6.1","Cell RNA - fHDF\/TERT166 [nTPM]":"3.1","Cell RNA - GAMG [nTPM]":"8.5","Cell RNA - HaCaT [nTPM]":"4.6","Cell RNA - HAP1 [nTPM]":"6.1","Cell RNA - HBEC3-KT [nTPM]":"6.8","Cell RNA - HBF TERT88 [nTPM]":"10.4","Cell RNA - HDLM-2 [nTPM]":"6.3","Cell RNA - HEK 293 [nTPM]":"3.7","Cell RNA - HEL [nTPM]":"1.5","Cell RNA - HeLa [nTPM]":"3.9","Cell RNA - Hep G2 [nTPM]":"2.2","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"7.6","Cell RNA - HMC-1 [nTPM]":"3.5","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.4","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"4.5","Cell RNA - HUVEC TERT2 [nTPM]":"6.1","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"8.1","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"4.1","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"6.1","Cell RNA - OE19 [nTPM]":"4.9","Cell RNA - PC-3 [nTPM]":"7.5","Cell RNA - REH [nTPM]":"1.9","Cell RNA - RH-30 [nTPM]":"5.9","Cell RNA - RPMI-8226 [nTPM]":"4.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.5","Cell RNA - RT4 [nTPM]":"2.8","Cell RNA - SCLC-21H [nTPM]":"26.0","Cell RNA - SH-SY5Y [nTPM]":"14.4","Cell RNA - SiHa [nTPM]":"5.4","Cell RNA - SK-BR-3 [nTPM]":"3.4","Cell RNA - SK-MEL-30 [nTPM]":"11.2","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"4.3","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"5.3","Cell RNA - U-138 MG [nTPM]":"5.2","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"4.5","Cell RNA - U-251 MG [nTPM]":"8.7","Cell RNA - U-266\/70 [nTPM]":"4.2","Cell RNA - U-266\/84 [nTPM]":"5.3","Cell RNA - U-698 [nTPM]":"6.4","Cell RNA - U-87 MG [nTPM]":"9.5","Cell RNA - U-937 [nTPM]":"4.0","Cell RNA - WM-115 [nTPM]":"6.4","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"4.2","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"5.7","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"3.5","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"3.9","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.6","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.4","Single Cell Type RNA - Early spermatids [nTPM]":"25.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"55.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"2.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"51.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"8.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"3.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"57.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.6","Single Cell Type RNA - Spermatocytes [nTPM]":"39.6","Single Cell Type RNA - Spermatogonia [nTPM]":"6.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"ARL6IP1","Gene synonym":["AIP1","ARL6IP","ARMER","KIAA0069","SPG61"],"Ensembl":"ENSG00000170540","Gene description":"ADP ribosylation factor like GTPase 6 interacting protein 1","Uniprot":["Q15041"],"Chromosome":"16","Position":"18791669-18801572","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045307"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA045307":"AB_10961042"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-3"},"Tissue RNA - adipose tissue [nTPM]":"142.0","Tissue RNA - adrenal gland [nTPM]":"171.3","Tissue RNA - amygdala [nTPM]":"206.4","Tissue RNA - appendix [nTPM]":"77.7","Tissue RNA - basal ganglia [nTPM]":"217.3","Tissue RNA - bone marrow [nTPM]":"209.7","Tissue RNA - breast [nTPM]":"112.9","Tissue RNA - cerebellum [nTPM]":"200.6","Tissue RNA - cerebral cortex [nTPM]":"282.2","Tissue RNA - cervix [nTPM]":"79.2","Tissue RNA - choroid plexus [nTPM]":"182.4","Tissue RNA - colon [nTPM]":"140.9","Tissue RNA - duodenum [nTPM]":"138.8","Tissue RNA - endometrium 1 [nTPM]":"70.8","Tissue RNA - epididymis [nTPM]":"122.9","Tissue RNA - esophagus [nTPM]":"70.0","Tissue RNA - fallopian tube [nTPM]":"86.6","Tissue RNA - gallbladder [nTPM]":"131.9","Tissue RNA - heart muscle [nTPM]":"32.1","Tissue RNA - hippocampal formation [nTPM]":"227.7","Tissue RNA - hypothalamus [nTPM]":"209.2","Tissue RNA - kidney [nTPM]":"150.1","Tissue RNA - liver [nTPM]":"359.6","Tissue RNA - lung [nTPM]":"79.6","Tissue RNA - lymph node [nTPM]":"132.6","Tissue RNA - medulla oblongata [nTPM]":"192.0","Tissue RNA - midbrain [nTPM]":"197.8","Tissue RNA - ovary [nTPM]":"101.6","Tissue RNA - pancreas [nTPM]":"81.7","Tissue RNA - parathyroid gland [nTPM]":"180.6","Tissue RNA - pituitary gland [nTPM]":"40.7","Tissue RNA - placenta [nTPM]":"90.3","Tissue RNA - pons [nTPM]":"200.0","Tissue RNA - prostate [nTPM]":"75.9","Tissue RNA - rectum [nTPM]":"123.4","Tissue RNA - retina [nTPM]":"316.0","Tissue RNA - salivary gland [nTPM]":"84.3","Tissue RNA - seminal vesicle [nTPM]":"70.4","Tissue RNA - skeletal muscle [nTPM]":"23.1","Tissue RNA - skin 1 [nTPM]":"66.1","Tissue RNA - small intestine [nTPM]":"123.4","Tissue RNA - smooth muscle [nTPM]":"69.1","Tissue RNA - spinal cord [nTPM]":"185.0","Tissue RNA - spleen [nTPM]":"72.8","Tissue RNA - stomach 1 [nTPM]":"125.8","Tissue RNA - testis [nTPM]":"129.9","Tissue RNA - thalamus [nTPM]":"200.5","Tissue RNA - thymus [nTPM]":"158.5","Tissue RNA - thyroid gland [nTPM]":"112.5","Tissue RNA - tongue [nTPM]":"51.5","Tissue RNA - tonsil [nTPM]":"113.4","Tissue RNA - urinary bladder [nTPM]":"132.5","Tissue RNA - vagina [nTPM]":"47.4","Tissue RNA - white matter [nTPM]":"197.6","Cell RNA - A-431 [nTPM]":"375.3","Cell RNA - A549 [nTPM]":"334.6","Cell RNA - AF22 [nTPM]":"417.8","Cell RNA - AN3-CA [nTPM]":"331.6","Cell RNA - ASC diff [nTPM]":"146.7","Cell RNA - ASC TERT1 [nTPM]":"93.5","Cell RNA - BEWO [nTPM]":"373.2","Cell RNA - BJ [nTPM]":"208.9","Cell RNA - BJ hTERT+ [nTPM]":"196.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"311.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"246.7","Cell RNA - CACO-2 [nTPM]":"205.7","Cell RNA - CAPAN-2 [nTPM]":"851.1","Cell RNA - Daudi [nTPM]":"315.7","Cell RNA - EFO-21 [nTPM]":"388.4","Cell RNA - fHDF\/TERT166 [nTPM]":"198.0","Cell RNA - GAMG [nTPM]":"209.2","Cell RNA - HaCaT [nTPM]":"388.9","Cell RNA - HAP1 [nTPM]":"303.7","Cell RNA - HBEC3-KT [nTPM]":"144.2","Cell RNA - HBF TERT88 [nTPM]":"359.1","Cell RNA - HDLM-2 [nTPM]":"421.2","Cell RNA - HEK 293 [nTPM]":"137.1","Cell RNA - HEL [nTPM]":"227.9","Cell RNA - HeLa [nTPM]":"192.5","Cell RNA - Hep G2 [nTPM]":"549.1","Cell RNA - HHSteC [nTPM]":"116.4","Cell RNA - HL-60 [nTPM]":"329.9","Cell RNA - HMC-1 [nTPM]":"232.0","Cell RNA - HSkMC [nTPM]":"78.6","Cell RNA - hTCEpi [nTPM]":"137.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"216.2","Cell RNA - hTERT-HME1 [nTPM]":"224.0","Cell RNA - hTERT-RPE1 [nTPM]":"229.1","Cell RNA - HUVEC TERT2 [nTPM]":"316.1","Cell RNA - JURKAT [nTPM]":"180.5","Cell RNA - K-562 [nTPM]":"251.0","Cell RNA - Karpas-707 [nTPM]":"318.5","Cell RNA - LHCN-M2 [nTPM]":"607.6","Cell RNA - MCF7 [nTPM]":"331.4","Cell RNA - MOLT-4 [nTPM]":"229.9","Cell RNA - NB-4 [nTPM]":"238.3","Cell RNA - NTERA-2 [nTPM]":"520.0","Cell RNA - OE19 [nTPM]":"311.7","Cell RNA - PC-3 [nTPM]":"109.8","Cell RNA - REH [nTPM]":"387.9","Cell RNA - RH-30 [nTPM]":"535.9","Cell RNA - RPMI-8226 [nTPM]":"266.0","Cell RNA - RPTEC TERT1 [nTPM]":"337.8","Cell RNA - RT4 [nTPM]":"206.1","Cell RNA - SCLC-21H [nTPM]":"255.2","Cell RNA - SH-SY5Y [nTPM]":"287.5","Cell RNA - SiHa [nTPM]":"466.5","Cell RNA - SK-BR-3 [nTPM]":"279.8","Cell RNA - SK-MEL-30 [nTPM]":"204.5","Cell RNA - SuSa [nTPM]":"280.1","Cell RNA - T-47d [nTPM]":"576.1","Cell RNA - THP-1 [nTPM]":"315.9","Cell RNA - TIME [nTPM]":"189.2","Cell RNA - U-138 MG [nTPM]":"204.2","Cell RNA - U-2 OS [nTPM]":"192.9","Cell RNA - U-2197 [nTPM]":"147.1","Cell RNA - U-251 MG [nTPM]":"384.1","Cell RNA - U-266\/70 [nTPM]":"109.5","Cell RNA - U-266\/84 [nTPM]":"209.5","Cell RNA - U-698 [nTPM]":"383.2","Cell RNA - U-87 MG [nTPM]":"182.8","Cell RNA - U-937 [nTPM]":"215.6","Cell RNA - WM-115 [nTPM]":"405.5","Blood RNA - basophil [nTPM]":"211.4","Blood RNA - classical monocyte [nTPM]":"125.2","Blood RNA - eosinophil [nTPM]":"84.2","Blood RNA - gdT-cell [nTPM]":"179.4","Blood RNA - intermediate monocyte [nTPM]":"119.5","Blood RNA - MAIT T-cell [nTPM]":"167.0","Blood RNA - memory B-cell [nTPM]":"163.2","Blood RNA - memory CD4 T-cell [nTPM]":"159.0","Blood RNA - memory CD8 T-cell [nTPM]":"199.1","Blood RNA - myeloid DC [nTPM]":"127.4","Blood RNA - naive B-cell [nTPM]":"160.7","Blood RNA - naive CD4 T-cell [nTPM]":"137.9","Blood RNA - naive CD8 T-cell [nTPM]":"166.4","Blood RNA - neutrophil [nTPM]":"105.9","Blood RNA - NK-cell [nTPM]":"179.2","Blood RNA - non-classical monocyte [nTPM]":"133.3","Blood RNA - plasmacytoid DC [nTPM]":"221.6","Blood RNA - T-reg [nTPM]":"281.5","Blood RNA - total PBMC [nTPM]":"295.0","Brain RNA - amygdala [nTPM]":"206.4","Brain RNA - basal ganglia [nTPM]":"217.3","Brain RNA - cerebellum [nTPM]":"200.6","Brain RNA - cerebral cortex [nTPM]":"282.2","Brain RNA - hippocampal formation [nTPM]":"227.7","Brain RNA - hypothalamus [nTPM]":"209.2","Brain RNA - medulla oblongata [nTPM]":"192.0","Brain RNA - midbrain [nTPM]":"197.8","Brain RNA - pons [nTPM]":"200.0","Brain RNA - spinal cord [nTPM]":"185.0","Brain RNA - thalamus [nTPM]":"200.5","Brain RNA - white matter [nTPM]":"197.6","Single Cell Type RNA - Adipocytes [nTPM]":"306.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.0","Single Cell Type RNA - Astrocytes [nTPM]":"56.8","Single Cell Type RNA - B-cells [nTPM]":"170.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"372.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"241.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"170.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"309.6","Single Cell Type RNA - Bipolar cells [nTPM]":"189.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"256.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"216.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"361.8","Single Cell Type RNA - Club cells [nTPM]":"128.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"286.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"131.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"296.7","Single Cell Type RNA - dendritic cells [nTPM]":"164.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"269.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"174.1","Single Cell Type RNA - Ductal cells [nTPM]":"398.2","Single Cell Type RNA - Early spermatids [nTPM]":"74.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"93.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"61.7","Single Cell Type RNA - Endothelial cells [nTPM]":"188.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"145.9","Single Cell Type RNA - Erythroid cells [nTPM]":"503.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"203.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"385.4","Single Cell Type RNA - Fibroblasts [nTPM]":"150.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"257.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"158.3","Single Cell Type RNA - granulocytes [nTPM]":"135.8","Single Cell Type RNA - Granulosa cells [nTPM]":"198.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"275.5","Single Cell Type RNA - Hepatocytes [nTPM]":"457.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"253.9","Single Cell Type RNA - Horizontal cells [nTPM]":"89.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"94.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"234.6","Single Cell Type RNA - Ionocytes [nTPM]":"229.9","Single Cell Type RNA - Kupffer cells [nTPM]":"275.8","Single Cell Type RNA - Langerhans cells [nTPM]":"424.6","Single Cell Type RNA - Late spermatids [nTPM]":"42.7","Single Cell Type RNA - Leydig cells [nTPM]":"84.8","Single Cell Type RNA - Macrophages [nTPM]":"205.8","Single Cell Type RNA - Melanocytes [nTPM]":"200.9","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"267.3","Single Cell Type RNA - Muller glia cells [nTPM]":"318.5","Single Cell Type RNA - NK-cells [nTPM]":"142.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"57.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"50.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"271.0","Single Cell Type RNA - Paneth cells [nTPM]":"288.5","Single Cell Type RNA - Peritubular cells [nTPM]":"110.9","Single Cell Type RNA - Plasma cells [nTPM]":"107.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"219.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"217.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"189.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"126.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"218.0","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"125.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"118.6","Single Cell Type RNA - Spermatocytes [nTPM]":"193.6","Single Cell Type RNA - Spermatogonia [nTPM]":"56.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"295.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"326.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"326.6","Single Cell Type RNA - T-cells [nTPM]":"186.9","Single Cell Type RNA - Theca cells [nTPM]":"53.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"319.7","Single Cell Type RNA - Urothelial cells [nTPM]":"323.8"},{"Gene":"ARMS2","Gene synonym":["ARMD8","LOC387715"],"Ensembl":"ENSG00000254636","Gene description":"Age-related maculopathy susceptibility 2","Uniprot":["P0C7Q2"],"Chromosome":"10","Position":"122454653-122457352","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Age-related macular degeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"2.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"16.9","Late spermatids":"59.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067225"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067225":"AB_2685806"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"16.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"59.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.6","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ARR3","Gene synonym":["ARRX"],"Ensembl":"ENSG00000120500","Gene description":"Arrestin 3","Uniprot":["P36575"],"Chromosome":"X","Position":"70268305-70281840","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"170","RNA tissue specific nTPM":{"retina":"392.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1538.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"2.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063129"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA063129":"AB_2732696"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"392.2","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"2.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.7","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"46.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"1538.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"68.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"172.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ARV1","Gene synonym":[],"Ensembl":"ENSG00000173409","Gene description":"ARV1 homolog, fatty acid homeostasis modulator","Uniprot":["Q9H2C2"],"Chromosome":"1","Position":"230978981-231000733","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"116.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035709"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035709":"AB_2674744"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.27e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.6","Tissue RNA - adrenal gland [nTPM]":"18.4","Tissue RNA - amygdala [nTPM]":"23.4","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"24.5","Tissue RNA - bone marrow [nTPM]":"13.9","Tissue RNA - breast [nTPM]":"19.0","Tissue RNA - cerebellum [nTPM]":"26.2","Tissue RNA - cerebral cortex [nTPM]":"32.8","Tissue RNA - cervix [nTPM]":"12.2","Tissue RNA - choroid plexus [nTPM]":"25.7","Tissue RNA - colon [nTPM]":"24.6","Tissue RNA - duodenum [nTPM]":"16.4","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"22.9","Tissue RNA - esophagus [nTPM]":"15.7","Tissue RNA - fallopian tube [nTPM]":"14.3","Tissue RNA - gallbladder [nTPM]":"16.4","Tissue RNA - heart muscle [nTPM]":"30.1","Tissue RNA - hippocampal formation [nTPM]":"24.5","Tissue RNA - hypothalamus [nTPM]":"25.6","Tissue RNA - kidney [nTPM]":"25.2","Tissue RNA - liver [nTPM]":"26.2","Tissue RNA - lung [nTPM]":"15.0","Tissue RNA - lymph node [nTPM]":"14.8","Tissue RNA - medulla oblongata [nTPM]":"25.2","Tissue RNA - midbrain [nTPM]":"24.1","Tissue RNA - ovary [nTPM]":"11.2","Tissue RNA - pancreas [nTPM]":"17.5","Tissue RNA - parathyroid gland [nTPM]":"33.3","Tissue RNA - pituitary gland [nTPM]":"20.1","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"25.0","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"25.9","Tissue RNA - retina [nTPM]":"29.0","Tissue RNA - salivary gland [nTPM]":"22.0","Tissue RNA - seminal vesicle [nTPM]":"15.2","Tissue RNA - skeletal muscle [nTPM]":"21.7","Tissue RNA - skin 1 [nTPM]":"17.8","Tissue RNA - small intestine [nTPM]":"17.3","Tissue RNA - smooth muscle [nTPM]":"13.1","Tissue RNA - spinal cord [nTPM]":"25.7","Tissue RNA - spleen [nTPM]":"13.5","Tissue RNA - stomach 1 [nTPM]":"17.1","Tissue RNA - testis [nTPM]":"31.3","Tissue RNA - thalamus [nTPM]":"25.2","Tissue RNA - thymus [nTPM]":"15.0","Tissue RNA - thyroid gland [nTPM]":"21.9","Tissue RNA - tongue [nTPM]":"24.8","Tissue RNA - tonsil [nTPM]":"15.3","Tissue RNA - urinary bladder [nTPM]":"15.2","Tissue RNA - vagina [nTPM]":"11.2","Tissue RNA - white matter [nTPM]":"27.7","Cell RNA - A-431 [nTPM]":"40.8","Cell RNA - A549 [nTPM]":"43.6","Cell RNA - AF22 [nTPM]":"20.8","Cell RNA - AN3-CA [nTPM]":"25.1","Cell RNA - ASC diff [nTPM]":"29.6","Cell RNA - ASC TERT1 [nTPM]":"26.4","Cell RNA - BEWO [nTPM]":"20.1","Cell RNA - BJ [nTPM]":"19.0","Cell RNA - BJ hTERT+ [nTPM]":"34.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.3","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"31.4","Cell RNA - Daudi [nTPM]":"11.4","Cell RNA - EFO-21 [nTPM]":"22.7","Cell RNA - fHDF\/TERT166 [nTPM]":"21.3","Cell RNA - GAMG [nTPM]":"20.5","Cell RNA - HaCaT [nTPM]":"32.3","Cell RNA - HAP1 [nTPM]":"40.6","Cell RNA - HBEC3-KT [nTPM]":"25.5","Cell RNA - HBF TERT88 [nTPM]":"39.2","Cell RNA - HDLM-2 [nTPM]":"30.4","Cell RNA - HEK 293 [nTPM]":"55.7","Cell RNA - HEL [nTPM]":"36.8","Cell RNA - HeLa [nTPM]":"28.9","Cell RNA - Hep G2 [nTPM]":"22.1","Cell RNA - HHSteC [nTPM]":"30.5","Cell RNA - HL-60 [nTPM]":"53.6","Cell RNA - HMC-1 [nTPM]":"27.9","Cell RNA - HSkMC [nTPM]":"28.0","Cell RNA - hTCEpi [nTPM]":"25.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.1","Cell RNA - hTERT-HME1 [nTPM]":"20.9","Cell RNA - hTERT-RPE1 [nTPM]":"21.9","Cell RNA - HUVEC TERT2 [nTPM]":"22.5","Cell RNA - JURKAT [nTPM]":"34.7","Cell RNA - K-562 [nTPM]":"53.7","Cell RNA - Karpas-707 [nTPM]":"30.7","Cell RNA - LHCN-M2 [nTPM]":"22.2","Cell RNA - MCF7 [nTPM]":"14.3","Cell RNA - MOLT-4 [nTPM]":"22.3","Cell RNA - NB-4 [nTPM]":"16.4","Cell RNA - NTERA-2 [nTPM]":"27.1","Cell RNA - OE19 [nTPM]":"43.0","Cell RNA - PC-3 [nTPM]":"27.1","Cell RNA - REH [nTPM]":"25.2","Cell RNA - RH-30 [nTPM]":"32.1","Cell RNA - RPMI-8226 [nTPM]":"33.1","Cell RNA - RPTEC TERT1 [nTPM]":"47.1","Cell RNA - RT4 [nTPM]":"33.0","Cell RNA - SCLC-21H [nTPM]":"21.2","Cell RNA - SH-SY5Y [nTPM]":"32.6","Cell RNA - SiHa [nTPM]":"22.6","Cell RNA - SK-BR-3 [nTPM]":"26.6","Cell RNA - SK-MEL-30 [nTPM]":"57.9","Cell RNA - SuSa [nTPM]":"5.3","Cell RNA - T-47d [nTPM]":"46.6","Cell RNA - THP-1 [nTPM]":"46.6","Cell RNA - TIME [nTPM]":"13.9","Cell RNA - U-138 MG [nTPM]":"13.4","Cell RNA - U-2 OS [nTPM]":"8.7","Cell RNA - U-2197 [nTPM]":"23.6","Cell RNA - U-251 MG [nTPM]":"45.9","Cell RNA - U-266\/70 [nTPM]":"47.4","Cell RNA - U-266\/84 [nTPM]":"44.6","Cell RNA - U-698 [nTPM]":"28.9","Cell RNA - U-87 MG [nTPM]":"36.8","Cell RNA - U-937 [nTPM]":"45.9","Cell RNA - WM-115 [nTPM]":"36.7","Blood RNA - basophil [nTPM]":"9.1","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"8.5","Blood RNA - gdT-cell [nTPM]":"10.0","Blood RNA - intermediate monocyte [nTPM]":"12.2","Blood RNA - MAIT T-cell [nTPM]":"13.9","Blood RNA - memory B-cell [nTPM]":"18.1","Blood RNA - memory CD4 T-cell [nTPM]":"11.2","Blood RNA - memory CD8 T-cell [nTPM]":"12.4","Blood RNA - myeloid DC [nTPM]":"10.1","Blood RNA - naive B-cell [nTPM]":"11.2","Blood RNA - naive CD4 T-cell [nTPM]":"13.7","Blood RNA - naive CD8 T-cell [nTPM]":"13.0","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"12.7","Blood RNA - non-classical monocyte [nTPM]":"21.2","Blood RNA - plasmacytoid DC [nTPM]":"14.9","Blood RNA - T-reg [nTPM]":"15.4","Blood RNA - total PBMC [nTPM]":"9.0","Brain RNA - amygdala [nTPM]":"23.4","Brain RNA - basal ganglia [nTPM]":"24.5","Brain RNA - cerebellum [nTPM]":"26.2","Brain RNA - cerebral cortex [nTPM]":"32.8","Brain RNA - hippocampal formation [nTPM]":"24.5","Brain RNA - hypothalamus [nTPM]":"25.6","Brain RNA - medulla oblongata [nTPM]":"25.2","Brain RNA - midbrain [nTPM]":"24.1","Brain RNA - pons [nTPM]":"25.0","Brain RNA - spinal cord [nTPM]":"25.7","Brain RNA - thalamus [nTPM]":"25.2","Brain RNA - white matter [nTPM]":"27.7","Single Cell Type RNA - Adipocytes [nTPM]":"13.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.7","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"12.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"18.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"32.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"38.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.9","Single Cell Type RNA - dendritic cells [nTPM]":"12.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"24.1","Single Cell Type RNA - Early spermatids [nTPM]":"52.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"12.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"58.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"40.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.5","Single Cell Type RNA - Fibroblasts [nTPM]":"14.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.7","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"14.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"17.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.9","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.5","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"13.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"22.9","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"9.8","Single Cell Type RNA - Muller glia cells [nTPM]":"33.6","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.5","Single Cell Type RNA - Paneth cells [nTPM]":"11.5","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"14.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.6","Single Cell Type RNA - Spermatocytes [nTPM]":"116.7","Single Cell Type RNA - Spermatogonia [nTPM]":"21.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.6","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.4","Single Cell Type RNA - Urothelial cells [nTPM]":"20.9"},{"Gene":"ARX","Gene synonym":["CT121","EIEE1","ISSX","MRX29","MRX32","MRX33","MRX36","MRX38","MRX43","MRX54","MRX76","MRX87","MRXS1","PRTS"],"Ensembl":"ENSG00000004848","Gene description":"Aristaless related homeobox","Uniprot":["Q96QS3"],"Chromosome":"X","Position":"25003694-25016420","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Disease variant","Epilepsy","Lissencephaly","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.4","ovary":"78.7","skeletal muscle":"26.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Enteroendocrine cells":"83.7","Inhibitory neurons":"53.2","Leydig cells":"131.7","Peritubular cells":"70.0","Theca cells":"66.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"1.9","PC-3":"3.9","THP-1":"1.7","U-266\/70":"8.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.54e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"7.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"10.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"17.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"3.5","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"6.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"78.7","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"1.8","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"26.7","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"7.2","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"1.9","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.9","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"1.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"8.3","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.6","Brain RNA - basal ganglia [nTPM]":"10.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"17.4","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"6.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"83.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.4","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"131.7","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"70.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"66.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"ASB10","Gene synonym":["GLC1F"],"Ensembl":"ENSG00000146926","Gene description":"Ankyrin repeat and SOCS box containing 10","Uniprot":["Q8WXI3"],"Chromosome":"7","Position":"151175698-151187832","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Glaucoma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"26.7","skeletal muscle":"77.9","tongue":"14.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"12.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079685"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079685":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"26.7","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"77.9","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"14.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ASCL1","Gene synonym":["ASH1","bHLHa46","HASH1"],"Ensembl":"ENSG00000139352","Gene description":"Achaete-scute family bHLH transcription factor 1","Uniprot":["P50553"],"Chromosome":"12","Position":"102957674-102960513","Protein class":["Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"23.0","choroid plexus":"13.7","liver":"11.1","pituitary gland":"30.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"17.0","Enteroendocrine cells":"36.4","Oligodendrocyte precursor cells":"42.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"21.4","lung cancer":"11.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"21","RNA cell line specific nTPM":{"SCLC-21H":"53.7","SH-SY5Y":"29.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029217","HPA076307"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA029217":"AB_10669595","HPA076307":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"18.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"18.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"18.9","Tissue RNA - cerebral cortex [nTPM]":"23.0","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"13.7","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"18.2","Tissue RNA - hypothalamus [nTPM]":"16.8","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"11.1","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"20.1","Tissue RNA - midbrain [nTPM]":"18.1","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"30.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"19.9","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"18.7","Tissue RNA - thymus [nTPM]":"5.5","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"19.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"53.7","Cell RNA - SH-SY5Y [nTPM]":"29.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"1.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"18.7","Brain RNA - basal ganglia [nTPM]":"18.3","Brain RNA - cerebellum [nTPM]":"18.9","Brain RNA - cerebral cortex [nTPM]":"23.0","Brain RNA - hippocampal formation [nTPM]":"18.2","Brain RNA - hypothalamus [nTPM]":"16.8","Brain RNA - medulla oblongata [nTPM]":"20.1","Brain RNA - midbrain [nTPM]":"18.1","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"19.9","Brain RNA - thalamus [nTPM]":"18.7","Brain RNA - white matter [nTPM]":"19.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"42.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"ASPA","Gene synonym":["ACY2","ASP"],"Ensembl":"ENSG00000108381","Gene description":"Aspartoacylase","Uniprot":["P45381"],"Chromosome":"17","Position":"3472374-3503405","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"69.0","kidney":"38.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"49.7","Melanocytes":"46.2","Oligodendrocytes":"217.0","Peritubular cells":"48.2","Proximal enterocytes":"37.5","Proximal tubular cells":"74.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"7.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"5.4","ASC TERT1":"4.1","CACO-2":"3.8","HSkMC":"7.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022142","HPA022145"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA022142":"AB_1845102","HPA022145":"AB_1845103"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.9","Tissue RNA - adrenal gland [nTPM]":"4.3","Tissue RNA - amygdala [nTPM]":"25.9","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"46.4","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"4.1","Tissue RNA - cerebellum [nTPM]":"27.6","Tissue RNA - cerebral cortex [nTPM]":"40.9","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"14.2","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"11.2","Tissue RNA - endometrium 1 [nTPM]":"4.5","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"25.8","Tissue RNA - hypothalamus [nTPM]":"27.7","Tissue RNA - kidney [nTPM]":"38.2","Tissue RNA - liver [nTPM]":"15.0","Tissue RNA - lung [nTPM]":"3.5","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"30.4","Tissue RNA - midbrain [nTPM]":"35.4","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"29.5","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"4.9","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"11.9","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"24.7","Tissue RNA - spleen [nTPM]":"5.4","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"42.4","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"2.1","Tissue RNA - tongue [nTPM]":"15.0","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"6.3","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"69.0","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"5.4","Cell RNA - ASC TERT1 [nTPM]":"4.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"3.8","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"7.5","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"25.9","Brain RNA - basal ganglia [nTPM]":"46.4","Brain RNA - cerebellum [nTPM]":"27.6","Brain RNA - cerebral cortex [nTPM]":"40.9","Brain RNA - hippocampal formation [nTPM]":"25.8","Brain RNA - hypothalamus [nTPM]":"27.7","Brain RNA - medulla oblongata [nTPM]":"30.4","Brain RNA - midbrain [nTPM]":"35.4","Brain RNA - pons [nTPM]":"29.5","Brain RNA - spinal cord [nTPM]":"24.7","Brain RNA - thalamus [nTPM]":"42.4","Brain RNA - white matter [nTPM]":"69.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"12.1","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"15.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"11.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"49.7","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"48.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"74.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.6","Single Cell Type RNA - Spermatocytes [nTPM]":"11.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"28.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.7"},{"Gene":"ATAD1","Gene synonym":["FLJ14600","Msp1"],"Ensembl":"ENSG00000138138","Gene description":"ATPase family AAA domain containing 1","Uniprot":["Q8NBU5"],"Chromosome":"10","Position":"87751512-87841361","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Early spermatids":"987.5","Late spermatids":"1846.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037569"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli rim","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoli rim"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA037569":"AB_10672496"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.98e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.7","Tissue RNA - adrenal gland [nTPM]":"17.4","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"9.0","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"16.3","Tissue RNA - cerebellum [nTPM]":"11.3","Tissue RNA - cerebral cortex [nTPM]":"12.6","Tissue RNA - cervix [nTPM]":"16.0","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"18.2","Tissue RNA - duodenum [nTPM]":"10.9","Tissue RNA - endometrium 1 [nTPM]":"16.8","Tissue RNA - epididymis [nTPM]":"13.7","Tissue RNA - esophagus [nTPM]":"16.2","Tissue RNA - fallopian tube [nTPM]":"13.8","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"36.1","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"16.7","Tissue RNA - liver [nTPM]":"18.0","Tissue RNA - lung [nTPM]":"14.5","Tissue RNA - lymph node [nTPM]":"11.8","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"11.5","Tissue RNA - ovary [nTPM]":"15.9","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"28.5","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"15.2","Tissue RNA - pons [nTPM]":"11.1","Tissue RNA - prostate [nTPM]":"18.7","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"28.0","Tissue RNA - salivary gland [nTPM]":"14.9","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"37.2","Tissue RNA - skin 1 [nTPM]":"15.1","Tissue RNA - small intestine [nTPM]":"12.5","Tissue RNA - smooth muscle [nTPM]":"13.6","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"10.0","Tissue RNA - stomach 1 [nTPM]":"13.6","Tissue RNA - testis [nTPM]":"26.4","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"13.8","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"31.8","Tissue RNA - tonsil [nTPM]":"12.1","Tissue RNA - urinary bladder [nTPM]":"15.5","Tissue RNA - vagina [nTPM]":"16.0","Tissue RNA - white matter [nTPM]":"10.2","Cell RNA - A-431 [nTPM]":"18.8","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"20.8","Cell RNA - AN3-CA [nTPM]":"18.2","Cell RNA - ASC diff [nTPM]":"27.4","Cell RNA - ASC TERT1 [nTPM]":"29.5","Cell RNA - BEWO [nTPM]":"14.4","Cell RNA - BJ [nTPM]":"19.7","Cell RNA - BJ hTERT+ [nTPM]":"33.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.6","Cell RNA - CACO-2 [nTPM]":"14.6","Cell RNA - CAPAN-2 [nTPM]":"53.8","Cell RNA - Daudi [nTPM]":"17.6","Cell RNA - EFO-21 [nTPM]":"15.4","Cell RNA - fHDF\/TERT166 [nTPM]":"17.3","Cell RNA - GAMG [nTPM]":"9.8","Cell RNA - HaCaT [nTPM]":"31.3","Cell RNA - HAP1 [nTPM]":"18.9","Cell RNA - HBEC3-KT [nTPM]":"14.4","Cell RNA - HBF TERT88 [nTPM]":"21.2","Cell RNA - HDLM-2 [nTPM]":"18.6","Cell RNA - HEK 293 [nTPM]":"26.4","Cell RNA - HEL [nTPM]":"15.3","Cell RNA - HeLa [nTPM]":"24.0","Cell RNA - Hep G2 [nTPM]":"18.8","Cell RNA - HHSteC [nTPM]":"30.5","Cell RNA - HL-60 [nTPM]":"41.7","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"23.0","Cell RNA - hTCEpi [nTPM]":"45.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.7","Cell RNA - hTERT-HME1 [nTPM]":"42.1","Cell RNA - hTERT-RPE1 [nTPM]":"37.2","Cell RNA - HUVEC TERT2 [nTPM]":"12.7","Cell RNA - JURKAT [nTPM]":"14.1","Cell RNA - K-562 [nTPM]":"15.9","Cell RNA - Karpas-707 [nTPM]":"20.7","Cell RNA - LHCN-M2 [nTPM]":"22.7","Cell RNA - MCF7 [nTPM]":"11.2","Cell RNA - MOLT-4 [nTPM]":"23.1","Cell RNA - NB-4 [nTPM]":"22.9","Cell RNA - NTERA-2 [nTPM]":"16.4","Cell RNA - OE19 [nTPM]":"13.9","Cell RNA - PC-3 [nTPM]":"10.0","Cell RNA - REH [nTPM]":"15.8","Cell RNA - RH-30 [nTPM]":"13.2","Cell RNA - RPMI-8226 [nTPM]":"19.2","Cell RNA - RPTEC TERT1 [nTPM]":"28.9","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"31.5","Cell RNA - SiHa [nTPM]":"20.3","Cell RNA - SK-BR-3 [nTPM]":"12.3","Cell RNA - SK-MEL-30 [nTPM]":"32.0","Cell RNA - SuSa [nTPM]":"21.0","Cell RNA - T-47d [nTPM]":"29.1","Cell RNA - THP-1 [nTPM]":"18.0","Cell RNA - TIME [nTPM]":"19.3","Cell RNA - U-138 MG [nTPM]":"16.2","Cell RNA - U-2 OS [nTPM]":"13.9","Cell RNA - U-2197 [nTPM]":"11.2","Cell RNA - U-251 MG [nTPM]":"24.5","Cell RNA - U-266\/70 [nTPM]":"25.4","Cell RNA - U-266\/84 [nTPM]":"39.4","Cell RNA - U-698 [nTPM]":"22.5","Cell RNA - U-87 MG [nTPM]":"20.8","Cell RNA - U-937 [nTPM]":"23.7","Cell RNA - WM-115 [nTPM]":"11.5","Blood RNA - basophil [nTPM]":"8.4","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"6.3","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"10.3","Blood RNA - memory B-cell [nTPM]":"7.2","Blood RNA - memory CD4 T-cell [nTPM]":"7.3","Blood RNA - memory CD8 T-cell [nTPM]":"8.3","Blood RNA - myeloid DC [nTPM]":"5.4","Blood RNA - naive B-cell [nTPM]":"5.7","Blood RNA - naive CD4 T-cell [nTPM]":"9.1","Blood RNA - naive CD8 T-cell [nTPM]":"8.6","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"6.9","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"7.6","Blood RNA - total PBMC [nTPM]":"5.7","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"11.3","Brain RNA - cerebral cortex [nTPM]":"12.6","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"11.5","Brain RNA - pons [nTPM]":"11.1","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"10.2","Single Cell Type RNA - Adipocytes [nTPM]":"31.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.0","Single Cell Type RNA - Astrocytes [nTPM]":"46.4","Single Cell Type RNA - B-cells [nTPM]":"41.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"46.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"50.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"81.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"44.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.7","Single Cell Type RNA - dendritic cells [nTPM]":"35.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"37.0","Single Cell Type RNA - Early spermatids [nTPM]":"987.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.3","Single Cell Type RNA - Endothelial cells [nTPM]":"21.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.8","Single Cell Type RNA - Erythroid cells [nTPM]":"24.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"69.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.2","Single Cell Type RNA - Fibroblasts [nTPM]":"35.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.7","Single Cell Type RNA - granulocytes [nTPM]":"29.2","Single Cell Type RNA - Granulosa cells [nTPM]":"23.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"28.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.3","Single Cell Type RNA - Horizontal cells [nTPM]":"70.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"73.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.9","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"18.0","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"1846.8","Single Cell Type RNA - Leydig cells [nTPM]":"35.8","Single Cell Type RNA - Macrophages [nTPM]":"25.1","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"37.5","Single Cell Type RNA - monocytes [nTPM]":"16.1","Single Cell Type RNA - Muller glia cells [nTPM]":"59.6","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"58.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"52.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.0","Single Cell Type RNA - Paneth cells [nTPM]":"25.2","Single Cell Type RNA - Peritubular cells [nTPM]":"47.0","Single Cell Type RNA - Plasma cells [nTPM]":"32.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"44.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"54.8","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.8","Single Cell Type RNA - Spermatocytes [nTPM]":"77.2","Single Cell Type RNA - Spermatogonia [nTPM]":"29.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.4","Single Cell Type RNA - T-cells [nTPM]":"40.0","Single Cell Type RNA - Theca cells [nTPM]":"34.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.7","Single Cell Type RNA - Urothelial cells [nTPM]":"54.6"},{"Gene":"ATCAY","Gene synonym":["BNIP-H"],"Ensembl":"ENSG00000167654","Gene description":"ATCAY kinesin light chain interacting caytaxin","Uniprot":["Q86WG3"],"Chromosome":"19","Position":"3879864-3928082","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Neurogenesis","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"46.6","pituitary gland":"25.6","retina":"17.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"128.5","Excitatory neurons":"67.0","Horizontal cells":"47.1","Inhibitory neurons":"82.2","Oligodendrocyte precursor cells":"94.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"15.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"7.3","SCLC-21H":"13.2","SH-SY5Y":"9.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017755"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017755":"AB_2669655"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"6.9","Tissue RNA - amygdala [nTPM]":"32.1","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"34.6","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"46.6","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"29.8","Tissue RNA - hypothalamus [nTPM]":"36.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"17.8","Tissue RNA - midbrain [nTPM]":"13.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"25.6","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"16.7","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"17.6","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"17.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"24.6","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.5","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"7.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"13.2","Cell RNA - SH-SY5Y [nTPM]":"9.3","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.2","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"32.1","Brain RNA - basal ganglia [nTPM]":"34.6","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"46.6","Brain RNA - hippocampal formation [nTPM]":"29.8","Brain RNA - hypothalamus [nTPM]":"36.1","Brain RNA - medulla oblongata [nTPM]":"17.8","Brain RNA - midbrain [nTPM]":"13.8","Brain RNA - pons [nTPM]":"16.7","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"17.3","Brain RNA - white matter [nTPM]":"24.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"128.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"67.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"5.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"94.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"ATF6","Gene synonym":["ATF6A"],"Ensembl":"ENSG00000118217","Gene description":"Activating transcription factor 6","Uniprot":["P18850"],"Chromosome":"1","Position":"161766298-161977574","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Unfolded protein response"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005935"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005935":"AB_2667472"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-3"},"Tissue RNA - adipose tissue [nTPM]":"13.6","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"12.6","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"8.4","Tissue RNA - choroid plexus [nTPM]":"13.6","Tissue RNA - colon [nTPM]":"9.9","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"10.6","Tissue RNA - epididymis [nTPM]":"18.9","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"11.3","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"9.9","Tissue RNA - kidney [nTPM]":"14.6","Tissue RNA - liver [nTPM]":"22.0","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"10.6","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"34.4","Tissue RNA - parathyroid gland [nTPM]":"18.9","Tissue RNA - pituitary gland [nTPM]":"7.1","Tissue RNA - placenta [nTPM]":"18.0","Tissue RNA - pons [nTPM]":"10.5","Tissue RNA - prostate [nTPM]":"10.7","Tissue RNA - rectum [nTPM]":"11.2","Tissue RNA - retina [nTPM]":"16.7","Tissue RNA - salivary gland [nTPM]":"13.3","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"8.9","Tissue RNA - skin 1 [nTPM]":"11.2","Tissue RNA - small intestine [nTPM]":"9.4","Tissue RNA - smooth muscle [nTPM]":"12.8","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"11.3","Tissue RNA - stomach 1 [nTPM]":"11.2","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"8.4","Tissue RNA - thyroid gland [nTPM]":"15.1","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"11.1","Tissue RNA - urinary bladder [nTPM]":"13.7","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"23.3","Cell RNA - A549 [nTPM]":"17.9","Cell RNA - AF22 [nTPM]":"15.1","Cell RNA - AN3-CA [nTPM]":"22.4","Cell RNA - ASC diff [nTPM]":"18.6","Cell RNA - ASC TERT1 [nTPM]":"17.7","Cell RNA - BEWO [nTPM]":"26.7","Cell RNA - BJ [nTPM]":"27.8","Cell RNA - BJ hTERT+ [nTPM]":"25.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.2","Cell RNA - CACO-2 [nTPM]":"11.6","Cell RNA - CAPAN-2 [nTPM]":"38.2","Cell RNA - Daudi [nTPM]":"16.9","Cell RNA - EFO-21 [nTPM]":"39.6","Cell RNA - fHDF\/TERT166 [nTPM]":"34.6","Cell RNA - GAMG [nTPM]":"19.9","Cell RNA - HaCaT [nTPM]":"34.0","Cell RNA - HAP1 [nTPM]":"15.1","Cell RNA - HBEC3-KT [nTPM]":"18.6","Cell RNA - HBF TERT88 [nTPM]":"17.6","Cell RNA - HDLM-2 [nTPM]":"23.2","Cell RNA - HEK 293 [nTPM]":"12.9","Cell RNA - HEL [nTPM]":"15.9","Cell RNA - HeLa [nTPM]":"22.6","Cell RNA - Hep G2 [nTPM]":"12.7","Cell RNA - HHSteC [nTPM]":"40.3","Cell RNA - HL-60 [nTPM]":"29.7","Cell RNA - HMC-1 [nTPM]":"40.6","Cell RNA - HSkMC [nTPM]":"18.3","Cell RNA - hTCEpi [nTPM]":"29.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.2","Cell RNA - hTERT-HME1 [nTPM]":"53.3","Cell RNA - hTERT-RPE1 [nTPM]":"23.8","Cell RNA - HUVEC TERT2 [nTPM]":"40.3","Cell RNA - JURKAT [nTPM]":"22.7","Cell RNA - K-562 [nTPM]":"37.9","Cell RNA - Karpas-707 [nTPM]":"19.2","Cell RNA - LHCN-M2 [nTPM]":"19.3","Cell RNA - MCF7 [nTPM]":"23.0","Cell RNA - MOLT-4 [nTPM]":"15.9","Cell RNA - NB-4 [nTPM]":"17.3","Cell RNA - NTERA-2 [nTPM]":"12.2","Cell RNA - OE19 [nTPM]":"24.5","Cell RNA - PC-3 [nTPM]":"23.1","Cell RNA - REH [nTPM]":"13.7","Cell RNA - RH-30 [nTPM]":"21.4","Cell RNA - RPMI-8226 [nTPM]":"39.2","Cell RNA - RPTEC TERT1 [nTPM]":"19.3","Cell RNA - RT4 [nTPM]":"11.1","Cell RNA - SCLC-21H [nTPM]":"9.1","Cell RNA - SH-SY5Y [nTPM]":"13.8","Cell RNA - SiHa [nTPM]":"33.3","Cell RNA - SK-BR-3 [nTPM]":"19.8","Cell RNA - SK-MEL-30 [nTPM]":"41.0","Cell RNA - SuSa [nTPM]":"32.9","Cell RNA - T-47d [nTPM]":"24.5","Cell RNA - THP-1 [nTPM]":"39.2","Cell RNA - TIME [nTPM]":"54.4","Cell RNA - U-138 MG [nTPM]":"23.2","Cell RNA - U-2 OS [nTPM]":"21.9","Cell RNA - U-2197 [nTPM]":"8.7","Cell RNA - U-251 MG [nTPM]":"31.5","Cell RNA - U-266\/70 [nTPM]":"28.0","Cell RNA - U-266\/84 [nTPM]":"29.2","Cell RNA - U-698 [nTPM]":"20.4","Cell RNA - U-87 MG [nTPM]":"28.2","Cell RNA - U-937 [nTPM]":"5.1","Cell RNA - WM-115 [nTPM]":"29.0","Blood RNA - basophil [nTPM]":"9.7","Blood RNA - classical monocyte [nTPM]":"17.8","Blood RNA - eosinophil [nTPM]":"12.0","Blood RNA - gdT-cell [nTPM]":"9.2","Blood RNA - intermediate monocyte [nTPM]":"18.3","Blood RNA - MAIT T-cell [nTPM]":"9.0","Blood RNA - memory B-cell [nTPM]":"8.7","Blood RNA - memory CD4 T-cell [nTPM]":"8.3","Blood RNA - memory CD8 T-cell [nTPM]":"7.7","Blood RNA - myeloid DC [nTPM]":"12.8","Blood RNA - naive B-cell [nTPM]":"9.5","Blood RNA - naive CD4 T-cell [nTPM]":"9.5","Blood RNA - naive CD8 T-cell [nTPM]":"9.7","Blood RNA - neutrophil [nTPM]":"33.2","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"24.4","Blood RNA - plasmacytoid DC [nTPM]":"5.7","Blood RNA - T-reg [nTPM]":"9.6","Blood RNA - total PBMC [nTPM]":"10.6","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"9.9","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"10.5","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"40.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"102.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"85.1","Single Cell Type RNA - Astrocytes [nTPM]":"41.8","Single Cell Type RNA - B-cells [nTPM]":"31.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"38.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"67.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"49.2","Single Cell Type RNA - dendritic cells [nTPM]":"23.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"45.9","Single Cell Type RNA - Early spermatids [nTPM]":"13.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.3","Single Cell Type RNA - Endothelial cells [nTPM]":"49.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.1","Single Cell Type RNA - Erythroid cells [nTPM]":"17.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"79.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.1","Single Cell Type RNA - Fibroblasts [nTPM]":"46.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.2","Single Cell Type RNA - granulocytes [nTPM]":"54.3","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"53.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.3","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"69.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.2","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"59.5","Single Cell Type RNA - Langerhans cells [nTPM]":"59.4","Single Cell Type RNA - Late spermatids [nTPM]":"10.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"66.6","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"103.0","Single Cell Type RNA - monocytes [nTPM]":"62.0","Single Cell Type RNA - Muller glia cells [nTPM]":"34.1","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"60.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"105.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.9","Single Cell Type RNA - Paneth cells [nTPM]":"15.6","Single Cell Type RNA - Peritubular cells [nTPM]":"24.5","Single Cell Type RNA - Plasma cells [nTPM]":"53.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"61.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"61.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.8","Single Cell Type RNA - Spermatocytes [nTPM]":"43.1","Single Cell Type RNA - Spermatogonia [nTPM]":"30.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"47.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"103.0","Single Cell Type RNA - T-cells [nTPM]":"29.0","Single Cell Type RNA - Theca cells [nTPM]":"22.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.9","Single Cell Type RNA - Urothelial cells [nTPM]":"44.1"},{"Gene":"ATG5","Gene synonym":["APG5","APG5L","ASP","hAPG5"],"Ensembl":"ENSG00000057663","Gene description":"Autophagy related 5","Uniprot":["Q9H1Y0"],"Chromosome":"6","Position":"106045423-106325791","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis","Autophagy","Host-virus interaction","Immunity"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034432","CAB037309","HPA042973"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"CAB034432":"AB_2243288","CAB037309":"AB_796188","HPA042973":"AB_2678246"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.84e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.5","Tissue RNA - adrenal gland [nTPM]":"19.2","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"10.2","Tissue RNA - bone marrow [nTPM]":"8.1","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"13.2","Tissue RNA - cervix [nTPM]":"15.3","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"15.8","Tissue RNA - duodenum [nTPM]":"12.8","Tissue RNA - endometrium 1 [nTPM]":"14.9","Tissue RNA - epididymis [nTPM]":"16.6","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"14.7","Tissue RNA - gallbladder [nTPM]":"9.5","Tissue RNA - heart muscle [nTPM]":"9.7","Tissue RNA - hippocampal formation [nTPM]":"10.3","Tissue RNA - hypothalamus [nTPM]":"10.7","Tissue RNA - kidney [nTPM]":"14.4","Tissue RNA - liver [nTPM]":"17.7","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"10.0","Tissue RNA - midbrain [nTPM]":"10.3","Tissue RNA - ovary [nTPM]":"14.3","Tissue RNA - pancreas [nTPM]":"12.1","Tissue RNA - parathyroid gland [nTPM]":"11.8","Tissue RNA - pituitary gland [nTPM]":"7.9","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"15.3","Tissue RNA - rectum [nTPM]":"15.2","Tissue RNA - retina [nTPM]":"10.5","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"13.1","Tissue RNA - skeletal muscle [nTPM]":"15.7","Tissue RNA - skin 1 [nTPM]":"8.0","Tissue RNA - small intestine [nTPM]":"13.1","Tissue RNA - smooth muscle [nTPM]":"14.2","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"10.6","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"10.2","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"17.5","Tissue RNA - tongue [nTPM]":"15.2","Tissue RNA - tonsil [nTPM]":"9.8","Tissue RNA - urinary bladder [nTPM]":"13.4","Tissue RNA - vagina [nTPM]":"11.9","Tissue RNA - white matter [nTPM]":"10.5","Cell RNA - A-431 [nTPM]":"14.6","Cell RNA - A549 [nTPM]":"6.0","Cell RNA - AF22 [nTPM]":"10.3","Cell RNA - AN3-CA [nTPM]":"14.0","Cell RNA - ASC diff [nTPM]":"23.2","Cell RNA - ASC TERT1 [nTPM]":"24.0","Cell RNA - BEWO [nTPM]":"10.7","Cell RNA - BJ [nTPM]":"15.4","Cell RNA - BJ hTERT+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.2","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"8.6","Cell RNA - Daudi [nTPM]":"10.2","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"23.7","Cell RNA - GAMG [nTPM]":"25.0","Cell RNA - HaCaT [nTPM]":"10.2","Cell RNA - HAP1 [nTPM]":"15.2","Cell RNA - HBEC3-KT [nTPM]":"22.2","Cell RNA - HBF TERT88 [nTPM]":"39.2","Cell RNA - HDLM-2 [nTPM]":"4.6","Cell RNA - HEK 293 [nTPM]":"7.3","Cell RNA - HEL [nTPM]":"11.8","Cell RNA - HeLa [nTPM]":"6.8","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"25.0","Cell RNA - HL-60 [nTPM]":"14.6","Cell RNA - HMC-1 [nTPM]":"6.0","Cell RNA - HSkMC [nTPM]":"19.3","Cell RNA - hTCEpi [nTPM]":"24.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.1","Cell RNA - hTERT-HME1 [nTPM]":"20.0","Cell RNA - hTERT-RPE1 [nTPM]":"29.7","Cell RNA - HUVEC TERT2 [nTPM]":"23.9","Cell RNA - JURKAT [nTPM]":"9.4","Cell RNA - K-562 [nTPM]":"17.6","Cell RNA - Karpas-707 [nTPM]":"10.0","Cell RNA - LHCN-M2 [nTPM]":"25.7","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"6.0","Cell RNA - NB-4 [nTPM]":"17.5","Cell RNA - NTERA-2 [nTPM]":"11.9","Cell RNA - OE19 [nTPM]":"19.4","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"6.0","Cell RNA - RH-30 [nTPM]":"23.7","Cell RNA - RPMI-8226 [nTPM]":"7.9","Cell RNA - RPTEC TERT1 [nTPM]":"24.0","Cell RNA - RT4 [nTPM]":"10.3","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"9.4","Cell RNA - SK-BR-3 [nTPM]":"17.8","Cell RNA - SK-MEL-30 [nTPM]":"14.6","Cell RNA - SuSa [nTPM]":"18.6","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"27.5","Cell RNA - TIME [nTPM]":"19.8","Cell RNA - U-138 MG [nTPM]":"8.6","Cell RNA - U-2 OS [nTPM]":"4.8","Cell RNA - U-2197 [nTPM]":"10.1","Cell RNA - U-251 MG [nTPM]":"26.7","Cell RNA - U-266\/70 [nTPM]":"4.1","Cell RNA - U-266\/84 [nTPM]":"4.2","Cell RNA - U-698 [nTPM]":"9.3","Cell RNA - U-87 MG [nTPM]":"31.7","Cell RNA - U-937 [nTPM]":"19.6","Cell RNA - WM-115 [nTPM]":"16.1","Blood RNA - basophil [nTPM]":"4.7","Blood RNA - classical monocyte [nTPM]":"4.8","Blood RNA - eosinophil [nTPM]":"9.6","Blood RNA - gdT-cell [nTPM]":"2.9","Blood RNA - intermediate monocyte [nTPM]":"6.1","Blood RNA - MAIT T-cell [nTPM]":"8.4","Blood RNA - memory B-cell [nTPM]":"5.1","Blood RNA - memory CD4 T-cell [nTPM]":"5.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"5.3","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"6.0","Blood RNA - naive CD8 T-cell [nTPM]":"5.0","Blood RNA - neutrophil [nTPM]":"4.1","Blood RNA - NK-cell [nTPM]":"4.8","Blood RNA - non-classical monocyte [nTPM]":"8.8","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"6.9","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"10.2","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"13.2","Brain RNA - hippocampal formation [nTPM]":"10.3","Brain RNA - hypothalamus [nTPM]":"10.7","Brain RNA - medulla oblongata [nTPM]":"10.0","Brain RNA - midbrain [nTPM]":"10.3","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"10.2","Brain RNA - white matter [nTPM]":"10.5","Single Cell Type RNA - Adipocytes [nTPM]":"35.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.9","Single Cell Type RNA - Astrocytes [nTPM]":"24.2","Single Cell Type RNA - B-cells [nTPM]":"41.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"45.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"14.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"36.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.3","Single Cell Type RNA - dendritic cells [nTPM]":"46.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"48.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"39.6","Single Cell Type RNA - Early spermatids [nTPM]":"35.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.4","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"27.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"79.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.8","Single Cell Type RNA - Fibroblasts [nTPM]":"25.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.5","Single Cell Type RNA - granulocytes [nTPM]":"20.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"20.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.1","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"71.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.4","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"26.9","Single Cell Type RNA - Langerhans cells [nTPM]":"32.3","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"33.6","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"43.1","Single Cell Type RNA - monocytes [nTPM]":"44.6","Single Cell Type RNA - Muller glia cells [nTPM]":"18.3","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"43.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"49.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.5","Single Cell Type RNA - Paneth cells [nTPM]":"59.8","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"85.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"43.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.1","Single Cell Type RNA - Spermatocytes [nTPM]":"36.5","Single Cell Type RNA - Spermatogonia [nTPM]":"39.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.5","Single Cell Type RNA - T-cells [nTPM]":"47.3","Single Cell Type RNA - Theca cells [nTPM]":"21.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.6","Single Cell Type RNA - Urothelial cells [nTPM]":"43.0"},{"Gene":"ATL1","Gene synonym":["AD-FSP","FSP1","SPG3","SPG3A"],"Ensembl":"ENSG00000198513","Gene description":"Atlastin GTPase 1","Uniprot":["Q8WXF7"],"Chromosome":"14","Position":"50532509-50634017","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"42.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"138.6","Inhibitory neurons":"95.5","Oligodendrocyte precursor cells":"81.4","Oligodendrocytes":"136.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"22.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"22.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"19.8","SCLC-21H":"17.1","SH-SY5Y":"15.4","SiHa":"18.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027550"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027550":"AB_10600983"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"5.6","Tissue RNA - amygdala [nTPM]":"29.1","Tissue RNA - appendix [nTPM]":"3.3","Tissue RNA - basal ganglia [nTPM]":"33.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"11.3","Tissue RNA - cerebellum [nTPM]":"18.8","Tissue RNA - cerebral cortex [nTPM]":"42.8","Tissue RNA - cervix [nTPM]":"5.7","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"8.1","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"37.1","Tissue RNA - hypothalamus [nTPM]":"30.3","Tissue RNA - kidney [nTPM]":"4.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"25.2","Tissue RNA - midbrain [nTPM]":"21.5","Tissue RNA - ovary [nTPM]":"10.5","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"1.9","Tissue RNA - pituitary gland [nTPM]":"7.7","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"29.6","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"9.5","Tissue RNA - salivary gland [nTPM]":"13.2","Tissue RNA - seminal vesicle [nTPM]":"8.6","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"15.6","Tissue RNA - spinal cord [nTPM]":"24.9","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"25.0","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"30.0","Cell RNA - A-431 [nTPM]":"1.2","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.4","Cell RNA - BJ [nTPM]":"5.7","Cell RNA - BJ hTERT+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"4.1","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"2.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"8.4","Cell RNA - HBEC3-KT [nTPM]":"1.1","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"19.8","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"1.2","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"3.1","Cell RNA - HSkMC [nTPM]":"3.6","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.6","Cell RNA - hTERT-HME1 [nTPM]":"1.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"4.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"8.7","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"1.2","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"4.4","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"17.1","Cell RNA - SH-SY5Y [nTPM]":"15.4","Cell RNA - SiHa [nTPM]":"18.9","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"6.0","Cell RNA - U-2 OS [nTPM]":"4.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"2.9","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"4.7","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"22.9","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"29.1","Brain RNA - basal ganglia [nTPM]":"33.2","Brain RNA - cerebellum [nTPM]":"18.8","Brain RNA - cerebral cortex [nTPM]":"42.8","Brain RNA - hippocampal formation [nTPM]":"37.1","Brain RNA - hypothalamus [nTPM]":"30.3","Brain RNA - medulla oblongata [nTPM]":"25.2","Brain RNA - midbrain [nTPM]":"21.5","Brain RNA - pons [nTPM]":"29.6","Brain RNA - spinal cord [nTPM]":"24.9","Brain RNA - thalamus [nTPM]":"25.0","Brain RNA - white matter [nTPM]":"30.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"3.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"27.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"6.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.6","Single Cell Type RNA - Early spermatids [nTPM]":"31.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"138.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"14.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.3","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.6","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"95.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.7","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"23.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"81.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"136.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.2","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.8","Single Cell Type RNA - Spermatocytes [nTPM]":"31.9","Single Cell Type RNA - Spermatogonia [nTPM]":"5.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"ATL3","Gene synonym":["DKFZP564J0863"],"Ensembl":"ENSG00000184743","Gene description":"Atlastin GTPase 3","Uniprot":["Q6DD88"],"Chromosome":"11","Position":"63624087-63671921","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"264.4","Late spermatids":"728.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065702","HPA076616"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA065702":"AB_2685536","HPA076616":"AB_2732318"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Tissue RNA - adipose tissue [nTPM]":"30.6","Tissue RNA - adrenal gland [nTPM]":"18.1","Tissue RNA - amygdala [nTPM]":"11.6","Tissue RNA - appendix [nTPM]":"17.9","Tissue RNA - basal ganglia [nTPM]":"16.6","Tissue RNA - bone marrow [nTPM]":"13.2","Tissue RNA - breast [nTPM]":"22.1","Tissue RNA - cerebellum [nTPM]":"14.9","Tissue RNA - cerebral cortex [nTPM]":"12.6","Tissue RNA - cervix [nTPM]":"23.0","Tissue RNA - choroid plexus [nTPM]":"22.0","Tissue RNA - colon [nTPM]":"26.0","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"24.3","Tissue RNA - epididymis [nTPM]":"16.5","Tissue RNA - esophagus [nTPM]":"24.5","Tissue RNA - fallopian tube [nTPM]":"20.1","Tissue RNA - gallbladder [nTPM]":"15.9","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"17.7","Tissue RNA - lung [nTPM]":"18.8","Tissue RNA - lymph node [nTPM]":"12.6","Tissue RNA - medulla oblongata [nTPM]":"19.8","Tissue RNA - midbrain [nTPM]":"16.4","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"15.4","Tissue RNA - parathyroid gland [nTPM]":"13.3","Tissue RNA - pituitary gland [nTPM]":"6.6","Tissue RNA - placenta [nTPM]":"14.9","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"16.7","Tissue RNA - rectum [nTPM]":"16.6","Tissue RNA - retina [nTPM]":"4.0","Tissue RNA - salivary gland [nTPM]":"15.4","Tissue RNA - seminal vesicle [nTPM]":"20.4","Tissue RNA - skeletal muscle [nTPM]":"6.3","Tissue RNA - skin 1 [nTPM]":"25.2","Tissue RNA - small intestine [nTPM]":"13.7","Tissue RNA - smooth muscle [nTPM]":"33.2","Tissue RNA - spinal cord [nTPM]":"16.8","Tissue RNA - spleen [nTPM]":"16.9","Tissue RNA - stomach 1 [nTPM]":"17.4","Tissue RNA - testis [nTPM]":"36.9","Tissue RNA - thalamus [nTPM]":"15.5","Tissue RNA - thymus [nTPM]":"10.8","Tissue RNA - thyroid gland [nTPM]":"20.9","Tissue RNA - tongue [nTPM]":"9.6","Tissue RNA - tonsil [nTPM]":"15.4","Tissue RNA - urinary bladder [nTPM]":"27.1","Tissue RNA - vagina [nTPM]":"19.4","Tissue RNA - white matter [nTPM]":"20.6","Cell RNA - A-431 [nTPM]":"44.2","Cell RNA - A549 [nTPM]":"39.4","Cell RNA - AF22 [nTPM]":"11.7","Cell RNA - AN3-CA [nTPM]":"28.4","Cell RNA - ASC diff [nTPM]":"59.2","Cell RNA - ASC TERT1 [nTPM]":"82.5","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"53.2","Cell RNA - BJ hTERT+ [nTPM]":"60.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.0","Cell RNA - CACO-2 [nTPM]":"32.9","Cell RNA - CAPAN-2 [nTPM]":"69.7","Cell RNA - Daudi [nTPM]":"26.3","Cell RNA - EFO-21 [nTPM]":"53.8","Cell RNA - fHDF\/TERT166 [nTPM]":"93.6","Cell RNA - GAMG [nTPM]":"40.0","Cell RNA - HaCaT [nTPM]":"28.3","Cell RNA - HAP1 [nTPM]":"21.8","Cell RNA - HBEC3-KT [nTPM]":"34.8","Cell RNA - HBF TERT88 [nTPM]":"69.8","Cell RNA - HDLM-2 [nTPM]":"40.4","Cell RNA - HEK 293 [nTPM]":"5.8","Cell RNA - HEL [nTPM]":"27.9","Cell RNA - HeLa [nTPM]":"41.8","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"40.7","Cell RNA - HL-60 [nTPM]":"53.2","Cell RNA - HMC-1 [nTPM]":"39.2","Cell RNA - HSkMC [nTPM]":"54.0","Cell RNA - hTCEpi [nTPM]":"55.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"69.1","Cell RNA - hTERT-HME1 [nTPM]":"42.8","Cell RNA - hTERT-RPE1 [nTPM]":"34.7","Cell RNA - HUVEC TERT2 [nTPM]":"56.3","Cell RNA - JURKAT [nTPM]":"28.5","Cell RNA - K-562 [nTPM]":"30.6","Cell RNA - Karpas-707 [nTPM]":"70.2","Cell RNA - LHCN-M2 [nTPM]":"59.6","Cell RNA - MCF7 [nTPM]":"46.6","Cell RNA - MOLT-4 [nTPM]":"19.2","Cell RNA - NB-4 [nTPM]":"30.7","Cell RNA - NTERA-2 [nTPM]":"14.9","Cell RNA - OE19 [nTPM]":"14.1","Cell RNA - PC-3 [nTPM]":"33.7","Cell RNA - REH [nTPM]":"40.7","Cell RNA - RH-30 [nTPM]":"29.3","Cell RNA - RPMI-8226 [nTPM]":"37.8","Cell RNA - RPTEC TERT1 [nTPM]":"41.2","Cell RNA - RT4 [nTPM]":"29.7","Cell RNA - SCLC-21H [nTPM]":"6.3","Cell RNA - SH-SY5Y [nTPM]":"17.0","Cell RNA - SiHa [nTPM]":"174.3","Cell RNA - SK-BR-3 [nTPM]":"37.6","Cell RNA - SK-MEL-30 [nTPM]":"50.5","Cell RNA - SuSa [nTPM]":"14.5","Cell RNA - T-47d [nTPM]":"65.7","Cell RNA - THP-1 [nTPM]":"19.1","Cell RNA - TIME [nTPM]":"79.1","Cell RNA - U-138 MG [nTPM]":"109.0","Cell RNA - U-2 OS [nTPM]":"51.9","Cell RNA - U-2197 [nTPM]":"105.3","Cell RNA - U-251 MG [nTPM]":"38.3","Cell RNA - U-266\/70 [nTPM]":"19.0","Cell RNA - U-266\/84 [nTPM]":"29.6","Cell RNA - U-698 [nTPM]":"51.4","Cell RNA - U-87 MG [nTPM]":"57.7","Cell RNA - U-937 [nTPM]":"33.6","Cell RNA - WM-115 [nTPM]":"67.1","Blood RNA - basophil [nTPM]":"7.1","Blood RNA - classical monocyte [nTPM]":"8.3","Blood RNA - eosinophil [nTPM]":"3.7","Blood RNA - gdT-cell [nTPM]":"8.9","Blood RNA - intermediate monocyte [nTPM]":"11.4","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"7.4","Blood RNA - memory CD8 T-cell [nTPM]":"7.3","Blood RNA - myeloid DC [nTPM]":"8.6","Blood RNA - naive B-cell [nTPM]":"4.2","Blood RNA - naive CD4 T-cell [nTPM]":"5.9","Blood RNA - naive CD8 T-cell [nTPM]":"8.2","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"13.4","Blood RNA - plasmacytoid DC [nTPM]":"4.3","Blood RNA - T-reg [nTPM]":"9.3","Blood RNA - total PBMC [nTPM]":"7.8","Brain RNA - amygdala [nTPM]":"11.6","Brain RNA - basal ganglia [nTPM]":"16.6","Brain RNA - cerebellum [nTPM]":"14.9","Brain RNA - cerebral cortex [nTPM]":"12.6","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"19.8","Brain RNA - midbrain [nTPM]":"16.4","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"16.8","Brain RNA - thalamus [nTPM]":"15.5","Brain RNA - white matter [nTPM]":"20.6","Single Cell Type RNA - Adipocytes [nTPM]":"56.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.2","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"18.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"43.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"4.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"29.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - dendritic cells [nTPM]":"28.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"45.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"41.2","Single Cell Type RNA - Early spermatids [nTPM]":"264.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.4","Single Cell Type RNA - Endothelial cells [nTPM]":"48.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"29.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"50.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.1","Single Cell Type RNA - Fibroblasts [nTPM]":"46.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.8","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"20.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"51.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.0","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"55.3","Single Cell Type RNA - Langerhans cells [nTPM]":"43.0","Single Cell Type RNA - Late spermatids [nTPM]":"728.4","Single Cell Type RNA - Leydig cells [nTPM]":"54.3","Single Cell Type RNA - Macrophages [nTPM]":"35.7","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"49.5","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"72.7","Single Cell Type RNA - Paneth cells [nTPM]":"24.7","Single Cell Type RNA - Peritubular cells [nTPM]":"67.4","Single Cell Type RNA - Plasma cells [nTPM]":"21.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"55.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.5","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.2","Single Cell Type RNA - Spermatocytes [nTPM]":"36.0","Single Cell Type RNA - Spermatogonia [nTPM]":"29.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"28.2","Single Cell Type RNA - Theca cells [nTPM]":"25.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.8","Single Cell Type RNA - Urothelial cells [nTPM]":"50.9"},{"Gene":"ATM","Gene synonym":["ATA","ATC","ATD","ATDC","TEL1","TELO1"],"Ensembl":"ENSG00000149311","Gene description":"ATM serine\/threonine kinase","Uniprot":["Q13315"],"Chromosome":"11","Position":"108222832-108369102","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"210.6","NK-cells":"339.8","Oligodendrocytes":"217.6","Rod photoreceptor cells":"200.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"78.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000102","HPA067142"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB000102":null,"HPA067142":"AB_2685789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"16.2","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"17.0","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"33.7","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"17.0","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"20.6","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"18.2","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"25.9","Tissue RNA - urinary bladder [nTPM]":"7.1","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"28.8","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"6.8","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"7.6","Cell RNA - ASC diff [nTPM]":"20.2","Cell RNA - ASC TERT1 [nTPM]":"29.1","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"18.3","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"9.0","Cell RNA - HDLM-2 [nTPM]":"12.3","Cell RNA - HEK 293 [nTPM]":"5.7","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"10.5","Cell RNA - HL-60 [nTPM]":"16.4","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"18.3","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"21.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"16.5","Cell RNA - K-562 [nTPM]":"12.4","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"10.6","Cell RNA - NB-4 [nTPM]":"18.5","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"8.6","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"9.7","Cell RNA - RPMI-8226 [nTPM]":"24.9","Cell RNA - RPTEC TERT1 [nTPM]":"8.1","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"9.0","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"11.1","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"20.6","Cell RNA - SuSa [nTPM]":"13.2","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"23.7","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"7.3","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"7.0","Cell RNA - U-698 [nTPM]":"78.3","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"19.0","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"5.5","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"16.5","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"11.1","Blood RNA - memory B-cell [nTPM]":"11.6","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.5","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"13.0","Blood RNA - naive CD4 T-cell [nTPM]":"21.1","Blood RNA - naive CD8 T-cell [nTPM]":"20.4","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"17.0","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"17.0","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"28.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"62.7","Single Cell Type RNA - B-cells [nTPM]":"146.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"111.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"19.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"210.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.9","Single Cell Type RNA - dendritic cells [nTPM]":"140.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"19.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.1","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"39.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.2","Single Cell Type RNA - Fibroblasts [nTPM]":"39.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.9","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"45.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"23.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.1","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"96.4","Single Cell Type RNA - Langerhans cells [nTPM]":"34.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"69.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"178.9","Single Cell Type RNA - monocytes [nTPM]":"63.2","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"339.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"96.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"200.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.2","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"37.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"147.7","Single Cell Type RNA - Theca cells [nTPM]":"52.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"ATN1","Gene synonym":["B37","D12S755E","DRPLA"],"Ensembl":"ENSG00000111676","Gene description":"Atrophin 1","Uniprot":["P54259"],"Chromosome":"12","Position":"6924463-6942321","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031619"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA031619":"AB_10601667"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"125.2","Tissue RNA - adrenal gland [nTPM]":"148.3","Tissue RNA - amygdala [nTPM]":"71.7","Tissue RNA - appendix [nTPM]":"33.7","Tissue RNA - basal ganglia [nTPM]":"60.1","Tissue RNA - bone marrow [nTPM]":"6.9","Tissue RNA - breast [nTPM]":"120.6","Tissue RNA - cerebellum [nTPM]":"94.2","Tissue RNA - cerebral cortex [nTPM]":"120.0","Tissue RNA - cervix [nTPM]":"143.8","Tissue RNA - choroid plexus [nTPM]":"14.5","Tissue RNA - colon [nTPM]":"155.4","Tissue RNA - duodenum [nTPM]":"36.3","Tissue RNA - endometrium 1 [nTPM]":"146.4","Tissue RNA - epididymis [nTPM]":"25.5","Tissue RNA - esophagus [nTPM]":"71.9","Tissue RNA - fallopian tube [nTPM]":"148.9","Tissue RNA - gallbladder [nTPM]":"43.2","Tissue RNA - heart muscle [nTPM]":"94.2","Tissue RNA - hippocampal formation [nTPM]":"66.8","Tissue RNA - hypothalamus [nTPM]":"75.7","Tissue RNA - kidney [nTPM]":"95.5","Tissue RNA - liver [nTPM]":"42.7","Tissue RNA - lung [nTPM]":"109.0","Tissue RNA - lymph node [nTPM]":"20.4","Tissue RNA - medulla oblongata [nTPM]":"81.3","Tissue RNA - midbrain [nTPM]":"70.6","Tissue RNA - ovary [nTPM]":"234.6","Tissue RNA - pancreas [nTPM]":"79.6","Tissue RNA - parathyroid gland [nTPM]":"56.7","Tissue RNA - pituitary gland [nTPM]":"188.9","Tissue RNA - placenta [nTPM]":"43.8","Tissue RNA - pons [nTPM]":"60.0","Tissue RNA - prostate [nTPM]":"117.6","Tissue RNA - rectum [nTPM]":"21.1","Tissue RNA - retina [nTPM]":"58.8","Tissue RNA - salivary gland [nTPM]":"89.8","Tissue RNA - seminal vesicle [nTPM]":"59.5","Tissue RNA - skeletal muscle [nTPM]":"81.9","Tissue RNA - skin 1 [nTPM]":"79.2","Tissue RNA - small intestine [nTPM]":"82.0","Tissue RNA - smooth muscle [nTPM]":"49.4","Tissue RNA - spinal cord [nTPM]":"41.2","Tissue RNA - spleen [nTPM]":"74.2","Tissue RNA - stomach 1 [nTPM]":"100.4","Tissue RNA - testis [nTPM]":"33.3","Tissue RNA - thalamus [nTPM]":"71.5","Tissue RNA - thymus [nTPM]":"16.3","Tissue RNA - thyroid gland [nTPM]":"189.0","Tissue RNA - tongue [nTPM]":"34.4","Tissue RNA - tonsil [nTPM]":"14.0","Tissue RNA - urinary bladder [nTPM]":"122.2","Tissue RNA - vagina [nTPM]":"108.8","Tissue RNA - white matter [nTPM]":"67.4","Cell RNA - A-431 [nTPM]":"56.4","Cell RNA - A549 [nTPM]":"72.1","Cell RNA - AF22 [nTPM]":"75.9","Cell RNA - AN3-CA [nTPM]":"154.7","Cell RNA - ASC diff [nTPM]":"69.6","Cell RNA - ASC TERT1 [nTPM]":"61.7","Cell RNA - BEWO [nTPM]":"126.3","Cell RNA - BJ [nTPM]":"65.5","Cell RNA - BJ hTERT+ [nTPM]":"55.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"45.8","Cell RNA - CACO-2 [nTPM]":"73.6","Cell RNA - CAPAN-2 [nTPM]":"65.6","Cell RNA - Daudi [nTPM]":"15.2","Cell RNA - EFO-21 [nTPM]":"20.4","Cell RNA - fHDF\/TERT166 [nTPM]":"80.8","Cell RNA - GAMG [nTPM]":"54.1","Cell RNA - HaCaT [nTPM]":"36.8","Cell RNA - HAP1 [nTPM]":"46.2","Cell RNA - HBEC3-KT [nTPM]":"63.8","Cell RNA - HBF TERT88 [nTPM]":"33.3","Cell RNA - HDLM-2 [nTPM]":"178.0","Cell RNA - HEK 293 [nTPM]":"46.3","Cell RNA - HEL [nTPM]":"70.6","Cell RNA - HeLa [nTPM]":"71.7","Cell RNA - Hep G2 [nTPM]":"35.6","Cell RNA - HHSteC [nTPM]":"108.3","Cell RNA - HL-60 [nTPM]":"14.6","Cell RNA - HMC-1 [nTPM]":"103.8","Cell RNA - HSkMC [nTPM]":"101.8","Cell RNA - hTCEpi [nTPM]":"46.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"82.4","Cell RNA - hTERT-HME1 [nTPM]":"63.6","Cell RNA - hTERT-RPE1 [nTPM]":"112.5","Cell RNA - HUVEC TERT2 [nTPM]":"64.4","Cell RNA - JURKAT [nTPM]":"22.4","Cell RNA - K-562 [nTPM]":"61.1","Cell RNA - Karpas-707 [nTPM]":"29.9","Cell RNA - LHCN-M2 [nTPM]":"58.2","Cell RNA - MCF7 [nTPM]":"81.2","Cell RNA - MOLT-4 [nTPM]":"31.9","Cell RNA - NB-4 [nTPM]":"13.5","Cell RNA - NTERA-2 [nTPM]":"156.0","Cell RNA - OE19 [nTPM]":"26.2","Cell RNA - PC-3 [nTPM]":"30.1","Cell RNA - REH [nTPM]":"65.9","Cell RNA - RH-30 [nTPM]":"40.6","Cell RNA - RPMI-8226 [nTPM]":"11.2","Cell RNA - RPTEC TERT1 [nTPM]":"48.3","Cell RNA - RT4 [nTPM]":"78.3","Cell RNA - SCLC-21H [nTPM]":"23.4","Cell RNA - SH-SY5Y [nTPM]":"75.3","Cell RNA - SiHa [nTPM]":"66.5","Cell RNA - SK-BR-3 [nTPM]":"77.2","Cell RNA - SK-MEL-30 [nTPM]":"47.1","Cell RNA - SuSa [nTPM]":"73.6","Cell RNA - T-47d [nTPM]":"29.5","Cell RNA - THP-1 [nTPM]":"40.3","Cell RNA - TIME [nTPM]":"85.2","Cell RNA - U-138 MG [nTPM]":"76.7","Cell RNA - U-2 OS [nTPM]":"97.9","Cell RNA - U-2197 [nTPM]":"61.1","Cell RNA - U-251 MG [nTPM]":"102.2","Cell RNA - U-266\/70 [nTPM]":"22.7","Cell RNA - U-266\/84 [nTPM]":"8.1","Cell RNA - U-698 [nTPM]":"10.7","Cell RNA - U-87 MG [nTPM]":"60.1","Cell RNA - U-937 [nTPM]":"18.7","Cell RNA - WM-115 [nTPM]":"82.3","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"71.7","Brain RNA - basal ganglia [nTPM]":"60.1","Brain RNA - cerebellum [nTPM]":"94.2","Brain RNA - cerebral cortex [nTPM]":"120.0","Brain RNA - hippocampal formation [nTPM]":"66.8","Brain RNA - hypothalamus [nTPM]":"75.7","Brain RNA - medulla oblongata [nTPM]":"81.3","Brain RNA - midbrain [nTPM]":"70.6","Brain RNA - pons [nTPM]":"60.0","Brain RNA - spinal cord [nTPM]":"41.2","Brain RNA - thalamus [nTPM]":"71.5","Brain RNA - white matter [nTPM]":"67.4","Single Cell Type RNA - Adipocytes [nTPM]":"66.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.2","Single Cell Type RNA - Astrocytes [nTPM]":"76.4","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"26.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"51.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"57.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"20.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"20.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"61.2","Single Cell Type RNA - Endothelial cells [nTPM]":"40.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.3","Single Cell Type RNA - Fibroblasts [nTPM]":"30.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"51.7","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"37.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"39.7","Single Cell Type RNA - Hepatocytes [nTPM]":"8.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.9","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.9","Single Cell Type RNA - Langerhans cells [nTPM]":"21.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.5","Single Cell Type RNA - Leydig cells [nTPM]":"63.6","Single Cell Type RNA - Macrophages [nTPM]":"13.7","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"4.8","Single Cell Type RNA - Muller glia cells [nTPM]":"17.3","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.9","Single Cell Type RNA - Paneth cells [nTPM]":"25.3","Single Cell Type RNA - Peritubular cells [nTPM]":"52.6","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"39.5","Single Cell Type RNA - Spermatocytes [nTPM]":"9.7","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.1","Single Cell Type RNA - T-cells [nTPM]":"10.9","Single Cell Type RNA - Theca cells [nTPM]":"26.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.4","Single Cell Type RNA - Urothelial cells [nTPM]":"17.9"},{"Gene":"ATOH7","Gene synonym":["bHLHa13","Math5"],"Ensembl":"ENSG00000179774","Gene description":"Atonal bHLH transcription factor 7","Uniprot":["Q8N100"],"Chromosome":"10","Position":"68230595-68232113","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.0","liver":"3.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"2.1","Excitatory neurons":"1.7","Hepatocytes":"1.1","Spermatogonia":"1.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"SCLC-21H":"7.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"cerebellum":"28.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027008"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027008":"AB_10600783"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"3.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"7.5","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ATP13A2","Gene synonym":["CLN12","HSA9947","PARK9"],"Ensembl":"ENSG00000159363","Gene description":"ATPase cation transporting 13A2","Uniprot":["Q9NQ11"],"Chromosome":"1","Position":"16985958-17011928","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuronal ceroid lipofuscinosis","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"112.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"61.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"plasmacytoid DC":"20.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"20.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037038","CAB037111","HPA050910","HPA054717"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037038":"AB_1840715","CAB037111":"AB_1840714","HPA050910":"AB_2681269","HPA054717":"AB_2682583"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"},"Tissue RNA - adipose tissue [nTPM]":"15.3","Tissue RNA - adrenal gland [nTPM]":"18.6","Tissue RNA - amygdala [nTPM]":"49.7","Tissue RNA - appendix [nTPM]":"20.2","Tissue RNA - basal ganglia [nTPM]":"45.8","Tissue RNA - bone marrow [nTPM]":"11.6","Tissue RNA - breast [nTPM]":"14.3","Tissue RNA - cerebellum [nTPM]":"30.3","Tissue RNA - cerebral cortex [nTPM]":"81.2","Tissue RNA - cervix [nTPM]":"10.6","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"15.9","Tissue RNA - duodenum [nTPM]":"12.7","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"6.6","Tissue RNA - esophagus [nTPM]":"23.6","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"9.3","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"46.7","Tissue RNA - hypothalamus [nTPM]":"66.0","Tissue RNA - kidney [nTPM]":"16.6","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"17.9","Tissue RNA - lymph node [nTPM]":"17.7","Tissue RNA - medulla oblongata [nTPM]":"112.4","Tissue RNA - midbrain [nTPM]":"60.8","Tissue RNA - ovary [nTPM]":"8.7","Tissue RNA - pancreas [nTPM]":"55.7","Tissue RNA - parathyroid gland [nTPM]":"12.9","Tissue RNA - pituitary gland [nTPM]":"57.0","Tissue RNA - placenta [nTPM]":"12.6","Tissue RNA - pons [nTPM]":"110.8","Tissue RNA - prostate [nTPM]":"14.3","Tissue RNA - rectum [nTPM]":"9.8","Tissue RNA - retina [nTPM]":"22.8","Tissue RNA - salivary gland [nTPM]":"27.4","Tissue RNA - seminal vesicle [nTPM]":"7.9","Tissue RNA - skeletal muscle [nTPM]":"17.2","Tissue RNA - skin 1 [nTPM]":"16.5","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"32.0","Tissue RNA - spleen [nTPM]":"26.0","Tissue RNA - stomach 1 [nTPM]":"19.3","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"64.1","Tissue RNA - thymus [nTPM]":"9.5","Tissue RNA - thyroid gland [nTPM]":"16.7","Tissue RNA - tongue [nTPM]":"5.3","Tissue RNA - tonsil [nTPM]":"10.3","Tissue RNA - urinary bladder [nTPM]":"12.9","Tissue RNA - vagina [nTPM]":"12.1","Tissue RNA - white matter [nTPM]":"44.3","Cell RNA - A-431 [nTPM]":"28.3","Cell RNA - A549 [nTPM]":"27.4","Cell RNA - AF22 [nTPM]":"14.7","Cell RNA - AN3-CA [nTPM]":"60.8","Cell RNA - ASC diff [nTPM]":"13.8","Cell RNA - ASC TERT1 [nTPM]":"12.2","Cell RNA - BEWO [nTPM]":"40.8","Cell RNA - BJ [nTPM]":"15.8","Cell RNA - BJ hTERT+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.6","Cell RNA - CACO-2 [nTPM]":"48.9","Cell RNA - CAPAN-2 [nTPM]":"31.4","Cell RNA - Daudi [nTPM]":"12.5","Cell RNA - EFO-21 [nTPM]":"65.9","Cell RNA - fHDF\/TERT166 [nTPM]":"26.9","Cell RNA - GAMG [nTPM]":"14.6","Cell RNA - HaCaT [nTPM]":"43.1","Cell RNA - HAP1 [nTPM]":"32.1","Cell RNA - HBEC3-KT [nTPM]":"59.5","Cell RNA - HBF TERT88 [nTPM]":"6.2","Cell RNA - HDLM-2 [nTPM]":"17.2","Cell RNA - HEK 293 [nTPM]":"58.5","Cell RNA - HEL [nTPM]":"43.7","Cell RNA - HeLa [nTPM]":"28.0","Cell RNA - Hep G2 [nTPM]":"27.2","Cell RNA - HHSteC [nTPM]":"17.5","Cell RNA - HL-60 [nTPM]":"15.6","Cell RNA - HMC-1 [nTPM]":"19.6","Cell RNA - HSkMC [nTPM]":"10.0","Cell RNA - hTCEpi [nTPM]":"31.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"47.1","Cell RNA - hTERT-HME1 [nTPM]":"36.6","Cell RNA - hTERT-RPE1 [nTPM]":"55.0","Cell RNA - HUVEC TERT2 [nTPM]":"32.3","Cell RNA - JURKAT [nTPM]":"32.2","Cell RNA - K-562 [nTPM]":"28.2","Cell RNA - Karpas-707 [nTPM]":"22.6","Cell RNA - LHCN-M2 [nTPM]":"70.2","Cell RNA - MCF7 [nTPM]":"22.2","Cell RNA - MOLT-4 [nTPM]":"18.4","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"23.2","Cell RNA - OE19 [nTPM]":"66.3","Cell RNA - PC-3 [nTPM]":"20.0","Cell RNA - REH [nTPM]":"20.0","Cell RNA - RH-30 [nTPM]":"60.1","Cell RNA - RPMI-8226 [nTPM]":"50.7","Cell RNA - RPTEC TERT1 [nTPM]":"19.0","Cell RNA - RT4 [nTPM]":"42.8","Cell RNA - SCLC-21H [nTPM]":"40.9","Cell RNA - SH-SY5Y [nTPM]":"27.4","Cell RNA - SiHa [nTPM]":"73.8","Cell RNA - SK-BR-3 [nTPM]":"87.7","Cell RNA - SK-MEL-30 [nTPM]":"60.2","Cell RNA - SuSa [nTPM]":"18.8","Cell RNA - T-47d [nTPM]":"29.9","Cell RNA - THP-1 [nTPM]":"19.6","Cell RNA - TIME [nTPM]":"34.4","Cell RNA - U-138 MG [nTPM]":"18.0","Cell RNA - U-2 OS [nTPM]":"34.5","Cell RNA - U-2197 [nTPM]":"30.8","Cell RNA - U-251 MG [nTPM]":"33.1","Cell RNA - U-266\/70 [nTPM]":"4.8","Cell RNA - U-266\/84 [nTPM]":"6.1","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"34.6","Cell RNA - U-937 [nTPM]":"85.2","Cell RNA - WM-115 [nTPM]":"30.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"20.6","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"49.7","Brain RNA - basal ganglia [nTPM]":"45.8","Brain RNA - cerebellum [nTPM]":"30.3","Brain RNA - cerebral cortex [nTPM]":"81.2","Brain RNA - hippocampal formation [nTPM]":"46.7","Brain RNA - hypothalamus [nTPM]":"66.0","Brain RNA - medulla oblongata [nTPM]":"112.4","Brain RNA - midbrain [nTPM]":"60.8","Brain RNA - pons [nTPM]":"110.8","Brain RNA - spinal cord [nTPM]":"32.0","Brain RNA - thalamus [nTPM]":"64.1","Brain RNA - white matter [nTPM]":"44.3","Single Cell Type RNA - Adipocytes [nTPM]":"18.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"8.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"35.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.8","Single Cell Type RNA - dendritic cells [nTPM]":"33.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.8","Single Cell Type RNA - Endothelial cells [nTPM]":"14.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.6","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.0","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"20.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.4","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"61.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"17.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"10.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"6.1","Single Cell Type RNA - Muller glia cells [nTPM]":"34.0","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"57.0","Single Cell Type RNA - Paneth cells [nTPM]":"49.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"5.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.7","Single Cell Type RNA - Spermatocytes [nTPM]":"13.6","Single Cell Type RNA - Spermatogonia [nTPM]":"16.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"11.1","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"12.8"},{"Gene":"ATP1A1","Gene synonym":[],"Ensembl":"ENSG00000163399","Gene description":"ATPase Na+\/K+ transporting subunit alpha 1","Uniprot":["P05023"],"Chromosome":"1","Position":"116372668-116410261","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Epilepsy","FDA approved drug targets","Mental retardation","Neurodegeneration","Neuropathy","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"1482.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"1879.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-MEL-30":"2979.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018702","CAB069993"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"420000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB018702":"AB_626713","CAB069993":"AB_2060979"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.42e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.98e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.01e-4"},"Tissue RNA - adipose tissue [nTPM]":"150.9","Tissue RNA - adrenal gland [nTPM]":"206.6","Tissue RNA - amygdala [nTPM]":"115.5","Tissue RNA - appendix [nTPM]":"144.1","Tissue RNA - basal ganglia [nTPM]":"135.7","Tissue RNA - bone marrow [nTPM]":"104.3","Tissue RNA - breast [nTPM]":"220.2","Tissue RNA - cerebellum [nTPM]":"176.4","Tissue RNA - cerebral cortex [nTPM]":"264.7","Tissue RNA - cervix [nTPM]":"137.6","Tissue RNA - choroid plexus [nTPM]":"209.2","Tissue RNA - colon [nTPM]":"580.5","Tissue RNA - duodenum [nTPM]":"785.5","Tissue RNA - endometrium 1 [nTPM]":"92.3","Tissue RNA - epididymis [nTPM]":"304.6","Tissue RNA - esophagus [nTPM]":"255.9","Tissue RNA - fallopian tube [nTPM]":"143.6","Tissue RNA - gallbladder [nTPM]":"361.3","Tissue RNA - heart muscle [nTPM]":"233.1","Tissue RNA - hippocampal formation [nTPM]":"176.0","Tissue RNA - hypothalamus [nTPM]":"133.9","Tissue RNA - kidney [nTPM]":"1127.5","Tissue RNA - liver [nTPM]":"132.5","Tissue RNA - lung [nTPM]":"255.7","Tissue RNA - lymph node [nTPM]":"89.7","Tissue RNA - medulla oblongata [nTPM]":"140.8","Tissue RNA - midbrain [nTPM]":"103.5","Tissue RNA - ovary [nTPM]":"137.7","Tissue RNA - pancreas [nTPM]":"661.3","Tissue RNA - parathyroid gland [nTPM]":"1482.3","Tissue RNA - pituitary gland [nTPM]":"160.6","Tissue RNA - placenta [nTPM]":"120.0","Tissue RNA - pons [nTPM]":"196.3","Tissue RNA - prostate [nTPM]":"176.4","Tissue RNA - rectum [nTPM]":"542.6","Tissue RNA - retina [nTPM]":"301.2","Tissue RNA - salivary gland [nTPM]":"721.9","Tissue RNA - seminal vesicle [nTPM]":"294.1","Tissue RNA - skeletal muscle [nTPM]":"147.3","Tissue RNA - skin 1 [nTPM]":"316.6","Tissue RNA - small intestine [nTPM]":"813.9","Tissue RNA - smooth muscle [nTPM]":"146.1","Tissue RNA - spinal cord [nTPM]":"117.4","Tissue RNA - spleen [nTPM]":"78.1","Tissue RNA - stomach 1 [nTPM]":"201.5","Tissue RNA - testis [nTPM]":"140.0","Tissue RNA - thalamus [nTPM]":"104.1","Tissue RNA - thymus [nTPM]":"92.8","Tissue RNA - thyroid gland [nTPM]":"744.4","Tissue RNA - tongue [nTPM]":"117.7","Tissue RNA - tonsil [nTPM]":"132.4","Tissue RNA - urinary bladder [nTPM]":"149.7","Tissue RNA - vagina [nTPM]":"187.4","Tissue RNA - white matter [nTPM]":"142.2","Cell RNA - A-431 [nTPM]":"399.8","Cell RNA - A549 [nTPM]":"144.8","Cell RNA - AF22 [nTPM]":"147.2","Cell RNA - AN3-CA [nTPM]":"74.5","Cell RNA - ASC diff [nTPM]":"288.8","Cell RNA - ASC TERT1 [nTPM]":"277.5","Cell RNA - BEWO [nTPM]":"750.8","Cell RNA - BJ [nTPM]":"232.9","Cell RNA - BJ hTERT+ [nTPM]":"462.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"281.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"396.6","Cell RNA - CACO-2 [nTPM]":"583.9","Cell RNA - CAPAN-2 [nTPM]":"278.5","Cell RNA - Daudi [nTPM]":"314.2","Cell RNA - EFO-21 [nTPM]":"321.3","Cell RNA - fHDF\/TERT166 [nTPM]":"279.0","Cell RNA - GAMG [nTPM]":"284.4","Cell RNA - HaCaT [nTPM]":"505.1","Cell RNA - HAP1 [nTPM]":"293.8","Cell RNA - HBEC3-KT [nTPM]":"493.7","Cell RNA - HBF TERT88 [nTPM]":"406.2","Cell RNA - HDLM-2 [nTPM]":"116.1","Cell RNA - HEK 293 [nTPM]":"324.2","Cell RNA - HEL [nTPM]":"183.5","Cell RNA - HeLa [nTPM]":"249.2","Cell RNA - Hep G2 [nTPM]":"498.4","Cell RNA - HHSteC [nTPM]":"220.1","Cell RNA - HL-60 [nTPM]":"465.2","Cell RNA - HMC-1 [nTPM]":"246.1","Cell RNA - HSkMC [nTPM]":"311.6","Cell RNA - hTCEpi [nTPM]":"808.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"328.4","Cell RNA - hTERT-HME1 [nTPM]":"429.0","Cell RNA - hTERT-RPE1 [nTPM]":"395.5","Cell RNA - HUVEC TERT2 [nTPM]":"350.8","Cell RNA - JURKAT [nTPM]":"187.4","Cell RNA - K-562 [nTPM]":"306.9","Cell RNA - Karpas-707 [nTPM]":"294.2","Cell RNA - LHCN-M2 [nTPM]":"253.0","Cell RNA - MCF7 [nTPM]":"793.7","Cell RNA - MOLT-4 [nTPM]":"189.6","Cell RNA - NB-4 [nTPM]":"167.7","Cell RNA - NTERA-2 [nTPM]":"346.0","Cell RNA - OE19 [nTPM]":"630.5","Cell RNA - PC-3 [nTPM]":"285.6","Cell RNA - REH [nTPM]":"179.7","Cell RNA - RH-30 [nTPM]":"343.4","Cell RNA - RPMI-8226 [nTPM]":"278.6","Cell RNA - RPTEC TERT1 [nTPM]":"1023.2","Cell RNA - RT4 [nTPM]":"405.1","Cell RNA - SCLC-21H [nTPM]":"143.8","Cell RNA - SH-SY5Y [nTPM]":"126.7","Cell RNA - SiHa [nTPM]":"363.0","Cell RNA - SK-BR-3 [nTPM]":"679.6","Cell RNA - SK-MEL-30 [nTPM]":"2979.2","Cell RNA - SuSa [nTPM]":"358.2","Cell RNA - T-47d [nTPM]":"179.1","Cell RNA - THP-1 [nTPM]":"265.9","Cell RNA - TIME [nTPM]":"311.9","Cell RNA - U-138 MG [nTPM]":"159.4","Cell RNA - U-2 OS [nTPM]":"221.4","Cell RNA - U-2197 [nTPM]":"415.4","Cell RNA - U-251 MG [nTPM]":"479.5","Cell RNA - U-266\/70 [nTPM]":"140.7","Cell RNA - U-266\/84 [nTPM]":"118.1","Cell RNA - U-698 [nTPM]":"238.0","Cell RNA - U-87 MG [nTPM]":"488.2","Cell RNA - U-937 [nTPM]":"263.1","Cell RNA - WM-115 [nTPM]":"956.1","Blood RNA - basophil [nTPM]":"19.2","Blood RNA - classical monocyte [nTPM]":"36.6","Blood RNA - eosinophil [nTPM]":"17.2","Blood RNA - gdT-cell [nTPM]":"59.7","Blood RNA - intermediate monocyte [nTPM]":"56.6","Blood RNA - MAIT T-cell [nTPM]":"62.8","Blood RNA - memory B-cell [nTPM]":"26.4","Blood RNA - memory CD4 T-cell [nTPM]":"66.9","Blood RNA - memory CD8 T-cell [nTPM]":"64.2","Blood RNA - myeloid DC [nTPM]":"59.6","Blood RNA - naive B-cell [nTPM]":"15.2","Blood RNA - naive CD4 T-cell [nTPM]":"76.5","Blood RNA - naive CD8 T-cell [nTPM]":"55.5","Blood RNA - neutrophil [nTPM]":"4.5","Blood RNA - NK-cell [nTPM]":"30.8","Blood RNA - non-classical monocyte [nTPM]":"86.0","Blood RNA - plasmacytoid DC [nTPM]":"30.4","Blood RNA - T-reg [nTPM]":"57.6","Blood RNA - total PBMC [nTPM]":"53.6","Brain RNA - amygdala [nTPM]":"115.5","Brain RNA - basal ganglia [nTPM]":"135.7","Brain RNA - cerebellum [nTPM]":"176.4","Brain RNA - cerebral cortex [nTPM]":"264.7","Brain RNA - hippocampal formation [nTPM]":"176.0","Brain RNA - hypothalamus [nTPM]":"133.9","Brain RNA - medulla oblongata [nTPM]":"140.8","Brain RNA - midbrain [nTPM]":"103.5","Brain RNA - pons [nTPM]":"196.3","Brain RNA - spinal cord [nTPM]":"117.4","Brain RNA - thalamus [nTPM]":"104.1","Brain RNA - white matter [nTPM]":"142.2","Single Cell Type RNA - Adipocytes [nTPM]":"199.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"275.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"295.3","Single Cell Type RNA - Astrocytes [nTPM]":"26.8","Single Cell Type RNA - B-cells [nTPM]":"84.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"276.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"336.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"220.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"390.9","Single Cell Type RNA - Bipolar cells [nTPM]":"101.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"189.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"145.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"74.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"579.0","Single Cell Type RNA - Club cells [nTPM]":"238.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"770.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"398.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"83.7","Single Cell Type RNA - dendritic cells [nTPM]":"89.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"789.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"373.7","Single Cell Type RNA - Ductal cells [nTPM]":"625.6","Single Cell Type RNA - Early spermatids [nTPM]":"31.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"205.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.3","Single Cell Type RNA - Endothelial cells [nTPM]":"201.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"176.4","Single Cell Type RNA - Erythroid cells [nTPM]":"89.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"130.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"315.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"160.6","Single Cell Type RNA - Fibroblasts [nTPM]":"141.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"134.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"372.1","Single Cell Type RNA - granulocytes [nTPM]":"43.8","Single Cell Type RNA - Granulosa cells [nTPM]":"212.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"144.2","Single Cell Type RNA - Hepatocytes [nTPM]":"71.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"129.8","Single Cell Type RNA - Horizontal cells [nTPM]":"102.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"123.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"353.4","Single Cell Type RNA - Ionocytes [nTPM]":"463.9","Single Cell Type RNA - Kupffer cells [nTPM]":"98.8","Single Cell Type RNA - Langerhans cells [nTPM]":"254.2","Single Cell Type RNA - Late spermatids [nTPM]":"19.3","Single Cell Type RNA - Leydig cells [nTPM]":"117.8","Single Cell Type RNA - Macrophages [nTPM]":"145.5","Single Cell Type RNA - Melanocytes [nTPM]":"208.1","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"56.9","Single Cell Type RNA - Muller glia cells [nTPM]":"556.8","Single Cell Type RNA - NK-cells [nTPM]":"64.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"77.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"60.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"187.6","Single Cell Type RNA - Paneth cells [nTPM]":"307.8","Single Cell Type RNA - Peritubular cells [nTPM]":"100.8","Single Cell Type RNA - Plasma cells [nTPM]":"73.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"271.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1879.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"308.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"171.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"147.7","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"109.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"147.4","Single Cell Type RNA - Spermatocytes [nTPM]":"20.2","Single Cell Type RNA - Spermatogonia [nTPM]":"35.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"320.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"268.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"67.6","Single Cell Type RNA - T-cells [nTPM]":"133.3","Single Cell Type RNA - Theca cells [nTPM]":"58.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"498.6","Single Cell Type RNA - Urothelial cells [nTPM]":"280.6"},{"Gene":"ATP1A2","Gene synonym":["FHM2","MHP2"],"Ensembl":"ENSG00000018625","Gene description":"ATPase Na+\/K+ transporting subunit alpha 2","Uniprot":["P50993"],"Chromosome":"1","Position":"160115759-160143591","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"515.9","skeletal muscle":"882.2","tongue":"478.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"515.8","Cardiomyocytes":"158.7","Microglial cells":"141.5","Muller glia cells":"73.0","Oligodendrocyte precursor cells":"94.0","Sertoli cells":"85.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"glioma":"91.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"51.9","HHSteC":"14.6","RH-30":"16.8","U-87 MG":"10.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022230"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022230":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-3"},"Tissue RNA - adipose tissue [nTPM]":"37.4","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"401.5","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"480.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"27.4","Tissue RNA - cerebellum [nTPM]":"419.8","Tissue RNA - cerebral cortex [nTPM]":"412.8","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"164.9","Tissue RNA - colon [nTPM]":"55.8","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"33.5","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"144.6","Tissue RNA - hippocampal formation [nTPM]":"337.4","Tissue RNA - hypothalamus [nTPM]":"398.5","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"429.5","Tissue RNA - midbrain [nTPM]":"478.8","Tissue RNA - ovary [nTPM]":"18.9","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"32.3","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"375.3","Tissue RNA - prostate [nTPM]":"28.5","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"58.5","Tissue RNA - salivary gland [nTPM]":"18.2","Tissue RNA - seminal vesicle [nTPM]":"28.5","Tissue RNA - skeletal muscle [nTPM]":"882.2","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"15.9","Tissue RNA - smooth muscle [nTPM]":"7.8","Tissue RNA - spinal cord [nTPM]":"365.0","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"15.7","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"515.9","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"478.0","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"29.9","Tissue RNA - vagina [nTPM]":"9.8","Tissue RNA - white matter [nTPM]":"327.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"51.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"5.9","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"14.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"16.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"4.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"10.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"401.5","Brain RNA - basal ganglia [nTPM]":"480.5","Brain RNA - cerebellum [nTPM]":"419.8","Brain RNA - cerebral cortex [nTPM]":"412.8","Brain RNA - hippocampal formation [nTPM]":"337.4","Brain RNA - hypothalamus [nTPM]":"398.5","Brain RNA - medulla oblongata [nTPM]":"429.5","Brain RNA - midbrain [nTPM]":"478.8","Brain RNA - pons [nTPM]":"375.3","Brain RNA - spinal cord [nTPM]":"365.0","Brain RNA - thalamus [nTPM]":"515.9","Brain RNA - white matter [nTPM]":"327.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"515.8","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"158.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"141.5","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"73.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"94.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"39.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"5.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"ATP1A3","Gene synonym":["DYT12"],"Ensembl":"ENSG00000105409","Gene description":"ATPase Na+\/K+ transporting subunit alpha 3","Uniprot":["P13637"],"Chromosome":"19","Position":"41966582-41997497","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Deafness","Disease variant","Dystonia","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"645.2","heart muscle":"157.7","retina":"292.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"418.1","Cone photoreceptor cells":"171.0","Horizontal cells":"213.7","Inhibitory neurons":"119.1","Late spermatids":"115.6","Rod photoreceptor cells":"291.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"21.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"57.7","JURKAT":"36.3","Karpas-707":"35.9","REH":"37.1","SCLC-21H":"128.2","SH-SY5Y":"57.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033630","HPA045367","HPA056446"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033630":"AB_781528","HPA045367":"AB_2679297","HPA056446":"AB_2683136"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.44e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.15e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"115.4","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"126.3","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"76.0","Tissue RNA - cerebral cortex [nTPM]":"645.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"157.7","Tissue RNA - hippocampal formation [nTPM]":"165.8","Tissue RNA - hypothalamus [nTPM]":"275.3","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"390.1","Tissue RNA - midbrain [nTPM]":"61.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"15.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"320.4","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"292.4","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.5","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"26.3","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"31.5","Tissue RNA - thalamus [nTPM]":"174.9","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"200.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"23.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"4.3","Cell RNA - Daudi [nTPM]":"57.7","Cell RNA - EFO-21 [nTPM]":"2.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"5.6","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"16.2","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"10.7","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"5.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"18.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"36.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"35.9","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"10.4","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"8.4","Cell RNA - PC-3 [nTPM]":"14.3","Cell RNA - REH [nTPM]":"37.1","Cell RNA - RH-30 [nTPM]":"18.5","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"128.2","Cell RNA - SH-SY5Y [nTPM]":"57.7","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"3.4","Cell RNA - THP-1 [nTPM]":"2.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"3.0","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"3.7","Cell RNA - U-266\/84 [nTPM]":"2.6","Cell RNA - U-698 [nTPM]":"12.7","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"20.6","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"115.4","Brain RNA - basal ganglia [nTPM]":"126.3","Brain RNA - cerebellum [nTPM]":"76.0","Brain RNA - cerebral cortex [nTPM]":"645.2","Brain RNA - hippocampal formation [nTPM]":"165.8","Brain RNA - hypothalamus [nTPM]":"275.3","Brain RNA - medulla oblongata [nTPM]":"390.1","Brain RNA - midbrain [nTPM]":"61.8","Brain RNA - pons [nTPM]":"320.4","Brain RNA - spinal cord [nTPM]":"26.3","Brain RNA - thalamus [nTPM]":"174.9","Brain RNA - white matter [nTPM]":"200.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"418.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"171.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"43.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"213.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"119.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"115.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"40.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"291.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"21.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"ATP6V1A","Gene synonym":["ATP6A1","ATP6V1A1","VA68","Vma1","VPP2"],"Ensembl":"ENSG00000114573","Gene description":"ATPase H+ transporting V1 subunit A","Uniprot":["P38606"],"Chromosome":"3","Position":"113747033-113812056","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"463.7","Late spermatids":"870.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"79.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"38.8","granulocytes":"79.2","monocytes":"37.0"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006910","HPA035084"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"700000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB006910":null,"HPA035084":"AB_2674454"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.82e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.1","Tissue RNA - adrenal gland [nTPM]":"32.2","Tissue RNA - amygdala [nTPM]":"40.1","Tissue RNA - appendix [nTPM]":"21.6","Tissue RNA - basal ganglia [nTPM]":"46.4","Tissue RNA - bone marrow [nTPM]":"16.6","Tissue RNA - breast [nTPM]":"24.5","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"53.0","Tissue RNA - cervix [nTPM]":"25.3","Tissue RNA - choroid plexus [nTPM]":"62.4","Tissue RNA - colon [nTPM]":"22.1","Tissue RNA - duodenum [nTPM]":"18.5","Tissue RNA - endometrium 1 [nTPM]":"14.2","Tissue RNA - epididymis [nTPM]":"15.1","Tissue RNA - esophagus [nTPM]":"22.7","Tissue RNA - fallopian tube [nTPM]":"19.0","Tissue RNA - gallbladder [nTPM]":"20.9","Tissue RNA - heart muscle [nTPM]":"9.0","Tissue RNA - hippocampal formation [nTPM]":"47.5","Tissue RNA - hypothalamus [nTPM]":"58.5","Tissue RNA - kidney [nTPM]":"92.7","Tissue RNA - liver [nTPM]":"36.4","Tissue RNA - lung [nTPM]":"24.5","Tissue RNA - lymph node [nTPM]":"25.1","Tissue RNA - medulla oblongata [nTPM]":"39.6","Tissue RNA - midbrain [nTPM]":"23.0","Tissue RNA - ovary [nTPM]":"11.3","Tissue RNA - pancreas [nTPM]":"20.9","Tissue RNA - parathyroid gland [nTPM]":"60.1","Tissue RNA - pituitary gland [nTPM]":"17.1","Tissue RNA - placenta [nTPM]":"24.5","Tissue RNA - pons [nTPM]":"39.0","Tissue RNA - prostate [nTPM]":"20.9","Tissue RNA - rectum [nTPM]":"22.5","Tissue RNA - retina [nTPM]":"58.7","Tissue RNA - salivary gland [nTPM]":"37.5","Tissue RNA - seminal vesicle [nTPM]":"14.9","Tissue RNA - skeletal muscle [nTPM]":"7.9","Tissue RNA - skin 1 [nTPM]":"25.0","Tissue RNA - small intestine [nTPM]":"15.9","Tissue RNA - smooth muscle [nTPM]":"15.8","Tissue RNA - spinal cord [nTPM]":"16.9","Tissue RNA - spleen [nTPM]":"26.5","Tissue RNA - stomach 1 [nTPM]":"22.1","Tissue RNA - testis [nTPM]":"18.1","Tissue RNA - thalamus [nTPM]":"28.4","Tissue RNA - thymus [nTPM]":"22.9","Tissue RNA - thyroid gland [nTPM]":"40.8","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"28.0","Tissue RNA - urinary bladder [nTPM]":"19.6","Tissue RNA - vagina [nTPM]":"14.2","Tissue RNA - white matter [nTPM]":"21.9","Cell RNA - A-431 [nTPM]":"61.7","Cell RNA - A549 [nTPM]":"27.4","Cell RNA - AF22 [nTPM]":"33.9","Cell RNA - AN3-CA [nTPM]":"29.7","Cell RNA - ASC diff [nTPM]":"70.0","Cell RNA - ASC TERT1 [nTPM]":"30.9","Cell RNA - BEWO [nTPM]":"36.0","Cell RNA - BJ [nTPM]":"32.7","Cell RNA - BJ hTERT+ [nTPM]":"49.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"46.1","Cell RNA - CACO-2 [nTPM]":"52.4","Cell RNA - CAPAN-2 [nTPM]":"48.3","Cell RNA - Daudi [nTPM]":"50.4","Cell RNA - EFO-21 [nTPM]":"75.5","Cell RNA - fHDF\/TERT166 [nTPM]":"48.0","Cell RNA - GAMG [nTPM]":"37.3","Cell RNA - HaCaT [nTPM]":"39.1","Cell RNA - HAP1 [nTPM]":"77.5","Cell RNA - HBEC3-KT [nTPM]":"43.2","Cell RNA - HBF TERT88 [nTPM]":"43.8","Cell RNA - HDLM-2 [nTPM]":"23.1","Cell RNA - HEK 293 [nTPM]":"21.4","Cell RNA - HEL [nTPM]":"44.8","Cell RNA - HeLa [nTPM]":"39.3","Cell RNA - Hep G2 [nTPM]":"40.6","Cell RNA - HHSteC [nTPM]":"57.6","Cell RNA - HL-60 [nTPM]":"33.2","Cell RNA - HMC-1 [nTPM]":"50.0","Cell RNA - HSkMC [nTPM]":"42.0","Cell RNA - hTCEpi [nTPM]":"29.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.7","Cell RNA - hTERT-HME1 [nTPM]":"30.2","Cell RNA - hTERT-RPE1 [nTPM]":"52.0","Cell RNA - HUVEC TERT2 [nTPM]":"55.7","Cell RNA - JURKAT [nTPM]":"25.1","Cell RNA - K-562 [nTPM]":"52.0","Cell RNA - Karpas-707 [nTPM]":"37.0","Cell RNA - LHCN-M2 [nTPM]":"50.5","Cell RNA - MCF7 [nTPM]":"40.5","Cell RNA - MOLT-4 [nTPM]":"24.4","Cell RNA - NB-4 [nTPM]":"14.9","Cell RNA - NTERA-2 [nTPM]":"42.8","Cell RNA - OE19 [nTPM]":"42.9","Cell RNA - PC-3 [nTPM]":"34.3","Cell RNA - REH [nTPM]":"20.8","Cell RNA - RH-30 [nTPM]":"24.6","Cell RNA - RPMI-8226 [nTPM]":"57.4","Cell RNA - RPTEC TERT1 [nTPM]":"92.5","Cell RNA - RT4 [nTPM]":"58.0","Cell RNA - SCLC-21H [nTPM]":"65.4","Cell RNA - SH-SY5Y [nTPM]":"24.1","Cell RNA - SiHa [nTPM]":"57.3","Cell RNA - SK-BR-3 [nTPM]":"38.6","Cell RNA - SK-MEL-30 [nTPM]":"44.9","Cell RNA - SuSa [nTPM]":"46.4","Cell RNA - T-47d [nTPM]":"58.5","Cell RNA - THP-1 [nTPM]":"26.6","Cell RNA - TIME [nTPM]":"51.4","Cell RNA - U-138 MG [nTPM]":"31.1","Cell RNA - U-2 OS [nTPM]":"23.1","Cell RNA - U-2197 [nTPM]":"21.7","Cell RNA - U-251 MG [nTPM]":"19.8","Cell RNA - U-266\/70 [nTPM]":"38.4","Cell RNA - U-266\/84 [nTPM]":"44.5","Cell RNA - U-698 [nTPM]":"46.2","Cell RNA - U-87 MG [nTPM]":"61.1","Cell RNA - U-937 [nTPM]":"41.2","Cell RNA - WM-115 [nTPM]":"35.3","Blood RNA - basophil [nTPM]":"26.8","Blood RNA - classical monocyte [nTPM]":"37.0","Blood RNA - eosinophil [nTPM]":"12.8","Blood RNA - gdT-cell [nTPM]":"6.3","Blood RNA - intermediate monocyte [nTPM]":"27.7","Blood RNA - MAIT T-cell [nTPM]":"5.9","Blood RNA - memory B-cell [nTPM]":"8.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.6","Blood RNA - memory CD8 T-cell [nTPM]":"6.0","Blood RNA - myeloid DC [nTPM]":"38.8","Blood RNA - naive B-cell [nTPM]":"6.8","Blood RNA - naive CD4 T-cell [nTPM]":"5.4","Blood RNA - naive CD8 T-cell [nTPM]":"6.2","Blood RNA - neutrophil [nTPM]":"79.2","Blood RNA - NK-cell [nTPM]":"9.2","Blood RNA - non-classical monocyte [nTPM]":"23.9","Blood RNA - plasmacytoid DC [nTPM]":"10.8","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"16.7","Brain RNA - amygdala [nTPM]":"40.1","Brain RNA - basal ganglia [nTPM]":"46.4","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"53.0","Brain RNA - hippocampal formation [nTPM]":"47.5","Brain RNA - hypothalamus [nTPM]":"58.5","Brain RNA - medulla oblongata [nTPM]":"39.6","Brain RNA - midbrain [nTPM]":"23.0","Brain RNA - pons [nTPM]":"39.0","Brain RNA - spinal cord [nTPM]":"16.9","Brain RNA - thalamus [nTPM]":"28.4","Brain RNA - white matter [nTPM]":"21.9","Single Cell Type RNA - Adipocytes [nTPM]":"18.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.0","Single Cell Type RNA - Astrocytes [nTPM]":"43.4","Single Cell Type RNA - B-cells [nTPM]":"24.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"94.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"32.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"99.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.0","Single Cell Type RNA - dendritic cells [nTPM]":"20.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"82.2","Single Cell Type RNA - Ductal cells [nTPM]":"29.5","Single Cell Type RNA - Early spermatids [nTPM]":"463.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.5","Single Cell Type RNA - Endothelial cells [nTPM]":"26.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"55.8","Single Cell Type RNA - Erythroid cells [nTPM]":"49.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"119.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"100.6","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"19.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.0","Single Cell Type RNA - Hepatocytes [nTPM]":"74.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"74.3","Single Cell Type RNA - Horizontal cells [nTPM]":"101.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"107.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.4","Single Cell Type RNA - Ionocytes [nTPM]":"197.4","Single Cell Type RNA - Kupffer cells [nTPM]":"104.7","Single Cell Type RNA - Langerhans cells [nTPM]":"73.3","Single Cell Type RNA - Late spermatids [nTPM]":"870.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"70.9","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"82.8","Single Cell Type RNA - Muller glia cells [nTPM]":"45.6","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"54.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"53.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.1","Single Cell Type RNA - Paneth cells [nTPM]":"30.5","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"23.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"80.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.6","Single Cell Type RNA - Spermatocytes [nTPM]":"28.7","Single Cell Type RNA - Spermatogonia [nTPM]":"15.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"47.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"43.9","Single Cell Type RNA - T-cells [nTPM]":"19.0","Single Cell Type RNA - Theca cells [nTPM]":"25.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.2","Single Cell Type RNA - Urothelial cells [nTPM]":"26.8"},{"Gene":"ATP7A","Gene synonym":["MNK"],"Ensembl":"ENSG00000165240","Gene description":"ATPase copper transporting alpha","Uniprot":["Q04656"],"Chromosome":"X","Position":"77910656-78050395","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"61.1","Microglial cells":"44.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012887","HPA048107"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA012887":"AB_1845205","HPA048107":"AB_2680266"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"4.3","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"3.6","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"2.5","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"2.3","Tissue RNA - lung [nTPM]":"4.5","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"2.4","Tissue RNA - parathyroid gland [nTPM]":"7.3","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"3.4","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"4.7","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"2.9","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"3.9","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"3.2","Cell RNA - A549 [nTPM]":"8.3","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"5.5","Cell RNA - ASC diff [nTPM]":"5.0","Cell RNA - ASC TERT1 [nTPM]":"5.3","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"4.8","Cell RNA - BJ hTERT+ [nTPM]":"6.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"3.6","Cell RNA - Daudi [nTPM]":"4.7","Cell RNA - EFO-21 [nTPM]":"6.9","Cell RNA - fHDF\/TERT166 [nTPM]":"4.8","Cell RNA - GAMG [nTPM]":"3.3","Cell RNA - HaCaT [nTPM]":"3.8","Cell RNA - HAP1 [nTPM]":"7.1","Cell RNA - HBEC3-KT [nTPM]":"3.9","Cell RNA - HBF TERT88 [nTPM]":"5.2","Cell RNA - HDLM-2 [nTPM]":"7.0","Cell RNA - HEK 293 [nTPM]":"4.8","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"7.8","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"6.3","Cell RNA - HL-60 [nTPM]":"4.1","Cell RNA - HMC-1 [nTPM]":"4.1","Cell RNA - HSkMC [nTPM]":"5.6","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.9","Cell RNA - hTERT-HME1 [nTPM]":"1.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.5","Cell RNA - HUVEC TERT2 [nTPM]":"7.3","Cell RNA - JURKAT [nTPM]":"4.7","Cell RNA - K-562 [nTPM]":"19.6","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"5.2","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"4.6","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"11.2","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"3.7","Cell RNA - RH-30 [nTPM]":"9.0","Cell RNA - RPMI-8226 [nTPM]":"15.8","Cell RNA - RPTEC TERT1 [nTPM]":"4.6","Cell RNA - RT4 [nTPM]":"8.8","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"20.4","Cell RNA - SiHa [nTPM]":"11.9","Cell RNA - SK-BR-3 [nTPM]":"2.8","Cell RNA - SK-MEL-30 [nTPM]":"6.0","Cell RNA - SuSa [nTPM]":"3.3","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"9.4","Cell RNA - U-138 MG [nTPM]":"3.7","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"5.2","Cell RNA - U-251 MG [nTPM]":"1.9","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"10.7","Cell RNA - U-698 [nTPM]":"5.2","Cell RNA - U-87 MG [nTPM]":"6.0","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"5.7","Blood RNA - basophil [nTPM]":"7.1","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"4.5","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"12.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"6.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"15.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"22.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.8","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"3.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"61.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.7","Single Cell Type RNA - Langerhans cells [nTPM]":"6.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"12.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"4.4","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.2","Single Cell Type RNA - Paneth cells [nTPM]":"4.1","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"10.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.2","Single Cell Type RNA - Urothelial cells [nTPM]":"6.6"},{"Gene":"ATP8A2","Gene synonym":["ATPIB","ML-1"],"Ensembl":"ENSG00000132932","Gene description":"ATPase phospholipid transporting 8A2","Uniprot":["Q9NTI2"],"Chromosome":"13","Position":"25371974-26025851","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"21.6","pituitary gland":"15.2","retina":"17.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"518.7","Inhibitory neurons":"727.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"19.9","JURKAT":"9.8","MOLT-4":"3.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039926","HPA040033"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA039926":"AB_10794205","HPA040033":"AB_2676809"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"8.0","Tissue RNA - cerebral cortex [nTPM]":"21.6","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"8.7","Tissue RNA - hypothalamus [nTPM]":"19.3","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"12.8","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"15.2","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"12.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"17.2","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"19.9","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"9.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"3.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.7","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"8.0","Brain RNA - cerebral cortex [nTPM]":"21.6","Brain RNA - hippocampal formation [nTPM]":"8.7","Brain RNA - hypothalamus [nTPM]":"19.3","Brain RNA - medulla oblongata [nTPM]":"12.8","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"12.1","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"21.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"95.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"39.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.6","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"518.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"3.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.2","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"727.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"30.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"88.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"91.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"19.8","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"10.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ATXN1","Gene synonym":["ATX1","D6S504E","SCA1"],"Ensembl":"ENSG00000124788","Gene description":"Ataxin 1","Uniprot":["P54253"],"Chromosome":"6","Position":"16299112-16761491","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Repressor","RNA-binding"],"Disease involvement":["Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"582.5","Inhibitory neurons":"519.0","Oligodendrocyte precursor cells":"318.2","Oligodendrocytes":"466.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"14.4"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"30.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008335","HPA070756"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA008335":"AB_1845129","HPA070756":"AB_2686306"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"3.2","Tissue RNA - appendix [nTPM]":"5.9","Tissue RNA - basal ganglia [nTPM]":"5.3","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"4.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"8.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"6.2","Tissue RNA - gallbladder [nTPM]":"5.7","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"8.4","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"4.1","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"6.9","Tissue RNA - lymph node [nTPM]":"4.2","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"5.5","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"4.9","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"3.8","Tissue RNA - retina [nTPM]":"13.9","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"6.2","Tissue RNA - skeletal muscle [nTPM]":"14.6","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"6.1","Tissue RNA - tongue [nTPM]":"14.8","Tissue RNA - tonsil [nTPM]":"3.1","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"4.5","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"4.4","Cell RNA - ASC TERT1 [nTPM]":"5.9","Cell RNA - BEWO [nTPM]":"5.8","Cell RNA - BJ [nTPM]":"4.8","Cell RNA - BJ hTERT+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.3","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"2.8","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"6.3","Cell RNA - fHDF\/TERT166 [nTPM]":"9.3","Cell RNA - GAMG [nTPM]":"3.7","Cell RNA - HaCaT [nTPM]":"4.2","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"3.0","Cell RNA - HBF TERT88 [nTPM]":"4.2","Cell RNA - HDLM-2 [nTPM]":"2.6","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"4.4","Cell RNA - Hep G2 [nTPM]":"9.0","Cell RNA - HHSteC [nTPM]":"7.0","Cell RNA - HL-60 [nTPM]":"4.2","Cell RNA - HMC-1 [nTPM]":"7.0","Cell RNA - HSkMC [nTPM]":"4.6","Cell RNA - hTCEpi [nTPM]":"5.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.1","Cell RNA - hTERT-HME1 [nTPM]":"5.1","Cell RNA - hTERT-RPE1 [nTPM]":"11.2","Cell RNA - HUVEC TERT2 [nTPM]":"5.9","Cell RNA - JURKAT [nTPM]":"0.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"5.3","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"2.3","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"4.8","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"4.3","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"5.8","Cell RNA - RPMI-8226 [nTPM]":"4.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.0","Cell RNA - RT4 [nTPM]":"7.6","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"2.5","Cell RNA - SiHa [nTPM]":"4.4","Cell RNA - SK-BR-3 [nTPM]":"5.5","Cell RNA - SK-MEL-30 [nTPM]":"9.1","Cell RNA - SuSa [nTPM]":"8.4","Cell RNA - T-47d [nTPM]":"3.6","Cell RNA - THP-1 [nTPM]":"7.2","Cell RNA - TIME [nTPM]":"9.1","Cell RNA - U-138 MG [nTPM]":"4.0","Cell RNA - U-2 OS [nTPM]":"6.1","Cell RNA - U-2197 [nTPM]":"4.8","Cell RNA - U-251 MG [nTPM]":"4.4","Cell RNA - U-266\/70 [nTPM]":"30.7","Cell RNA - U-266\/84 [nTPM]":"19.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"4.3","Cell RNA - WM-115 [nTPM]":"10.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"3.2","Brain RNA - basal ganglia [nTPM]":"5.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"8.4","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.9","Single Cell Type RNA - Astrocytes [nTPM]":"206.3","Single Cell Type RNA - B-cells [nTPM]":"20.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"91.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"72.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"48.9","Single Cell Type RNA - Bipolar cells [nTPM]":"39.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"26.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"100.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"48.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.7","Single Cell Type RNA - Early spermatids [nTPM]":"4.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"80.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"144.4","Single Cell Type RNA - Endothelial cells [nTPM]":"21.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"582.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.0","Single Cell Type RNA - Fibroblasts [nTPM]":"32.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"75.8","Single Cell Type RNA - granulocytes [nTPM]":"38.7","Single Cell Type RNA - Granulosa cells [nTPM]":"67.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"25.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.4","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"519.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"39.6","Single Cell Type RNA - Langerhans cells [nTPM]":"79.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.3","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"41.7","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"217.4","Single Cell Type RNA - monocytes [nTPM]":"42.3","Single Cell Type RNA - Muller glia cells [nTPM]":"24.1","Single Cell Type RNA - NK-cells [nTPM]":"33.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"318.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"466.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.3","Single Cell Type RNA - Paneth cells [nTPM]":"16.3","Single Cell Type RNA - Peritubular cells [nTPM]":"28.2","Single Cell Type RNA - Plasma cells [nTPM]":"82.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"56.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"99.9","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"6.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"48.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"61.5","Single Cell Type RNA - Theca cells [nTPM]":"6.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.7","Single Cell Type RNA - Urothelial cells [nTPM]":"63.8"},{"Gene":"ATXN10","Gene synonym":["E46L","FLJ37990","SCA10"],"Ensembl":"ENSG00000130638","Gene description":"Ataxin 10","Uniprot":["Q9UBB4"],"Chromosome":"22","Position":"45671798-45845307","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Ciliopathy","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049531"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"40000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA049531":"AB_2680806"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"40.9","Tissue RNA - adrenal gland [nTPM]":"59.5","Tissue RNA - amygdala [nTPM]":"42.2","Tissue RNA - appendix [nTPM]":"34.7","Tissue RNA - basal ganglia [nTPM]":"46.1","Tissue RNA - bone marrow [nTPM]":"41.9","Tissue RNA - breast [nTPM]":"41.7","Tissue RNA - cerebellum [nTPM]":"35.3","Tissue RNA - cerebral cortex [nTPM]":"56.8","Tissue RNA - cervix [nTPM]":"50.6","Tissue RNA - choroid plexus [nTPM]":"26.9","Tissue RNA - colon [nTPM]":"43.7","Tissue RNA - duodenum [nTPM]":"23.8","Tissue RNA - endometrium 1 [nTPM]":"50.0","Tissue RNA - epididymis [nTPM]":"39.0","Tissue RNA - esophagus [nTPM]":"46.4","Tissue RNA - fallopian tube [nTPM]":"56.1","Tissue RNA - gallbladder [nTPM]":"39.6","Tissue RNA - heart muscle [nTPM]":"74.5","Tissue RNA - hippocampal formation [nTPM]":"50.2","Tissue RNA - hypothalamus [nTPM]":"49.6","Tissue RNA - kidney [nTPM]":"53.5","Tissue RNA - liver [nTPM]":"64.8","Tissue RNA - lung [nTPM]":"38.2","Tissue RNA - lymph node [nTPM]":"48.3","Tissue RNA - medulla oblongata [nTPM]":"37.6","Tissue RNA - midbrain [nTPM]":"40.1","Tissue RNA - ovary [nTPM]":"57.7","Tissue RNA - pancreas [nTPM]":"57.4","Tissue RNA - parathyroid gland [nTPM]":"64.9","Tissue RNA - pituitary gland [nTPM]":"56.1","Tissue RNA - placenta [nTPM]":"48.8","Tissue RNA - pons [nTPM]":"42.1","Tissue RNA - prostate [nTPM]":"46.5","Tissue RNA - rectum [nTPM]":"36.3","Tissue RNA - retina [nTPM]":"55.1","Tissue RNA - salivary gland [nTPM]":"41.6","Tissue RNA - seminal vesicle [nTPM]":"40.9","Tissue RNA - skeletal muscle [nTPM]":"70.6","Tissue RNA - skin 1 [nTPM]":"34.9","Tissue RNA - small intestine [nTPM]":"27.8","Tissue RNA - smooth muscle [nTPM]":"50.2","Tissue RNA - spinal cord [nTPM]":"42.5","Tissue RNA - spleen [nTPM]":"34.2","Tissue RNA - stomach 1 [nTPM]":"34.4","Tissue RNA - testis [nTPM]":"57.3","Tissue RNA - thalamus [nTPM]":"46.5","Tissue RNA - thymus [nTPM]":"65.9","Tissue RNA - thyroid gland [nTPM]":"63.0","Tissue RNA - tongue [nTPM]":"59.3","Tissue RNA - tonsil [nTPM]":"51.6","Tissue RNA - urinary bladder [nTPM]":"51.1","Tissue RNA - vagina [nTPM]":"45.8","Tissue RNA - white matter [nTPM]":"44.5","Cell RNA - A-431 [nTPM]":"163.4","Cell RNA - A549 [nTPM]":"84.9","Cell RNA - AF22 [nTPM]":"156.2","Cell RNA - AN3-CA [nTPM]":"95.0","Cell RNA - ASC diff [nTPM]":"70.5","Cell RNA - ASC TERT1 [nTPM]":"107.6","Cell RNA - BEWO [nTPM]":"85.4","Cell RNA - BJ [nTPM]":"181.0","Cell RNA - BJ hTERT+ [nTPM]":"194.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"128.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"139.4","Cell RNA - CACO-2 [nTPM]":"42.9","Cell RNA - CAPAN-2 [nTPM]":"106.4","Cell RNA - Daudi [nTPM]":"169.3","Cell RNA - EFO-21 [nTPM]":"73.2","Cell RNA - fHDF\/TERT166 [nTPM]":"184.5","Cell RNA - GAMG [nTPM]":"66.4","Cell RNA - HaCaT [nTPM]":"94.4","Cell RNA - HAP1 [nTPM]":"114.3","Cell RNA - HBEC3-KT [nTPM]":"121.3","Cell RNA - HBF TERT88 [nTPM]":"137.7","Cell RNA - HDLM-2 [nTPM]":"32.8","Cell RNA - HEK 293 [nTPM]":"119.4","Cell RNA - HEL [nTPM]":"78.9","Cell RNA - HeLa [nTPM]":"141.7","Cell RNA - Hep G2 [nTPM]":"79.8","Cell RNA - HHSteC [nTPM]":"101.9","Cell RNA - HL-60 [nTPM]":"213.1","Cell RNA - HMC-1 [nTPM]":"56.4","Cell RNA - HSkMC [nTPM]":"109.0","Cell RNA - hTCEpi [nTPM]":"82.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"66.5","Cell RNA - hTERT-HME1 [nTPM]":"103.1","Cell RNA - hTERT-RPE1 [nTPM]":"153.1","Cell RNA - HUVEC TERT2 [nTPM]":"96.3","Cell RNA - JURKAT [nTPM]":"76.2","Cell RNA - K-562 [nTPM]":"58.7","Cell RNA - Karpas-707 [nTPM]":"89.8","Cell RNA - LHCN-M2 [nTPM]":"197.2","Cell RNA - MCF7 [nTPM]":"69.6","Cell RNA - MOLT-4 [nTPM]":"116.7","Cell RNA - NB-4 [nTPM]":"95.6","Cell RNA - NTERA-2 [nTPM]":"104.2","Cell RNA - OE19 [nTPM]":"90.8","Cell RNA - PC-3 [nTPM]":"64.0","Cell RNA - REH [nTPM]":"166.2","Cell RNA - RH-30 [nTPM]":"60.7","Cell RNA - RPMI-8226 [nTPM]":"135.9","Cell RNA - RPTEC TERT1 [nTPM]":"162.6","Cell RNA - RT4 [nTPM]":"152.3","Cell RNA - SCLC-21H [nTPM]":"86.9","Cell RNA - SH-SY5Y [nTPM]":"136.6","Cell RNA - SiHa [nTPM]":"113.5","Cell RNA - SK-BR-3 [nTPM]":"67.2","Cell RNA - SK-MEL-30 [nTPM]":"129.2","Cell RNA - SuSa [nTPM]":"119.8","Cell RNA - T-47d [nTPM]":"101.4","Cell RNA - THP-1 [nTPM]":"111.9","Cell RNA - TIME [nTPM]":"87.6","Cell RNA - U-138 MG [nTPM]":"127.5","Cell RNA - U-2 OS [nTPM]":"47.7","Cell RNA - U-2197 [nTPM]":"46.0","Cell RNA - U-251 MG [nTPM]":"61.4","Cell RNA - U-266\/70 [nTPM]":"87.8","Cell RNA - U-266\/84 [nTPM]":"57.3","Cell RNA - U-698 [nTPM]":"136.8","Cell RNA - U-87 MG [nTPM]":"79.5","Cell RNA - U-937 [nTPM]":"88.5","Cell RNA - WM-115 [nTPM]":"138.5","Blood RNA - basophil [nTPM]":"80.5","Blood RNA - classical monocyte [nTPM]":"99.9","Blood RNA - eosinophil [nTPM]":"91.8","Blood RNA - gdT-cell [nTPM]":"69.0","Blood RNA - intermediate monocyte [nTPM]":"121.7","Blood RNA - MAIT T-cell [nTPM]":"92.3","Blood RNA - memory B-cell [nTPM]":"72.1","Blood RNA - memory CD4 T-cell [nTPM]":"68.0","Blood RNA - memory CD8 T-cell [nTPM]":"84.3","Blood RNA - myeloid DC [nTPM]":"163.9","Blood RNA - naive B-cell [nTPM]":"72.6","Blood RNA - naive CD4 T-cell [nTPM]":"74.4","Blood RNA - naive CD8 T-cell [nTPM]":"71.9","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"86.2","Blood RNA - non-classical monocyte [nTPM]":"138.5","Blood RNA - plasmacytoid DC [nTPM]":"58.1","Blood RNA - T-reg [nTPM]":"70.8","Blood RNA - total PBMC [nTPM]":"120.2","Brain RNA - amygdala [nTPM]":"42.2","Brain RNA - basal ganglia [nTPM]":"46.1","Brain RNA - cerebellum [nTPM]":"35.3","Brain RNA - cerebral cortex [nTPM]":"56.8","Brain RNA - hippocampal formation [nTPM]":"50.2","Brain RNA - hypothalamus [nTPM]":"49.6","Brain RNA - medulla oblongata [nTPM]":"37.6","Brain RNA - midbrain [nTPM]":"40.1","Brain RNA - pons [nTPM]":"42.1","Brain RNA - spinal cord [nTPM]":"42.5","Brain RNA - thalamus [nTPM]":"46.5","Brain RNA - white matter [nTPM]":"44.5","Single Cell Type RNA - Adipocytes [nTPM]":"38.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.3","Single Cell Type RNA - Astrocytes [nTPM]":"127.3","Single Cell Type RNA - B-cells [nTPM]":"50.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"124.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"156.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"68.9","Single Cell Type RNA - Bipolar cells [nTPM]":"66.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"94.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"65.8","Single Cell Type RNA - Club cells [nTPM]":"76.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.9","Single Cell Type RNA - dendritic cells [nTPM]":"32.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"68.4","Single Cell Type RNA - Ductal cells [nTPM]":"91.1","Single Cell Type RNA - Early spermatids [nTPM]":"69.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"53.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"53.7","Single Cell Type RNA - Endothelial cells [nTPM]":"44.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"60.3","Single Cell Type RNA - Erythroid cells [nTPM]":"63.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"148.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"69.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"106.3","Single Cell Type RNA - Fibroblasts [nTPM]":"70.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.8","Single Cell Type RNA - granulocytes [nTPM]":"39.9","Single Cell Type RNA - Granulosa cells [nTPM]":"93.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.4","Single Cell Type RNA - Hepatocytes [nTPM]":"54.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"72.2","Single Cell Type RNA - Horizontal cells [nTPM]":"70.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"157.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.4","Single Cell Type RNA - Ionocytes [nTPM]":"79.3","Single Cell Type RNA - Kupffer cells [nTPM]":"49.0","Single Cell Type RNA - Langerhans cells [nTPM]":"36.5","Single Cell Type RNA - Late spermatids [nTPM]":"40.6","Single Cell Type RNA - Leydig cells [nTPM]":"57.5","Single Cell Type RNA - Macrophages [nTPM]":"48.3","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"103.0","Single Cell Type RNA - monocytes [nTPM]":"67.9","Single Cell Type RNA - Muller glia cells [nTPM]":"79.3","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"186.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"168.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.6","Single Cell Type RNA - Paneth cells [nTPM]":"24.0","Single Cell Type RNA - Peritubular cells [nTPM]":"75.6","Single Cell Type RNA - Plasma cells [nTPM]":"53.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"115.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"67.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.6","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"54.6","Single Cell Type RNA - Spermatocytes [nTPM]":"133.8","Single Cell Type RNA - Spermatogonia [nTPM]":"108.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"65.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.3","Single Cell Type RNA - T-cells [nTPM]":"47.8","Single Cell Type RNA - Theca cells [nTPM]":"102.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.5","Single Cell Type RNA - Urothelial cells [nTPM]":"102.0"},{"Gene":"ATXN2","Gene synonym":["ATX2","SCA2","TNRC13"],"Ensembl":"ENSG00000204842","Gene description":"Ataxin 2","Uniprot":["Q99700"],"Chromosome":"12","Position":"111443485-111599676","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Neurodegeneration","Parkinsonism","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"209.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018295","HPA020339","HPA021146"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9600","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018295":"AB_1845130","HPA020339":"AB_1845131","HPA021146":"AB_1845132"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.66e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.6","Tissue RNA - adrenal gland [nTPM]":"23.5","Tissue RNA - amygdala [nTPM]":"20.5","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"21.9","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"17.5","Tissue RNA - cerebellum [nTPM]":"22.8","Tissue RNA - cerebral cortex [nTPM]":"30.3","Tissue RNA - cervix [nTPM]":"21.6","Tissue RNA - choroid plexus [nTPM]":"20.8","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"11.2","Tissue RNA - endometrium 1 [nTPM]":"21.7","Tissue RNA - epididymis [nTPM]":"13.9","Tissue RNA - esophagus [nTPM]":"14.2","Tissue RNA - fallopian tube [nTPM]":"20.4","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"22.2","Tissue RNA - hippocampal formation [nTPM]":"20.5","Tissue RNA - hypothalamus [nTPM]":"29.9","Tissue RNA - kidney [nTPM]":"17.5","Tissue RNA - liver [nTPM]":"20.1","Tissue RNA - lung [nTPM]":"19.7","Tissue RNA - lymph node [nTPM]":"9.5","Tissue RNA - medulla oblongata [nTPM]":"25.2","Tissue RNA - midbrain [nTPM]":"26.0","Tissue RNA - ovary [nTPM]":"25.9","Tissue RNA - pancreas [nTPM]":"13.8","Tissue RNA - parathyroid gland [nTPM]":"18.6","Tissue RNA - pituitary gland [nTPM]":"21.9","Tissue RNA - placenta [nTPM]":"16.3","Tissue RNA - pons [nTPM]":"24.5","Tissue RNA - prostate [nTPM]":"19.4","Tissue RNA - rectum [nTPM]":"11.6","Tissue RNA - retina [nTPM]":"15.7","Tissue RNA - salivary gland [nTPM]":"14.5","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"25.8","Tissue RNA - skin 1 [nTPM]":"15.6","Tissue RNA - small intestine [nTPM]":"14.9","Tissue RNA - smooth muscle [nTPM]":"18.3","Tissue RNA - spinal cord [nTPM]":"18.6","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"16.3","Tissue RNA - testis [nTPM]":"23.2","Tissue RNA - thalamus [nTPM]":"22.7","Tissue RNA - thymus [nTPM]":"12.8","Tissue RNA - thyroid gland [nTPM]":"17.1","Tissue RNA - tongue [nTPM]":"20.8","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"19.6","Tissue RNA - vagina [nTPM]":"18.3","Tissue RNA - white matter [nTPM]":"25.8","Cell RNA - A-431 [nTPM]":"31.0","Cell RNA - A549 [nTPM]":"38.0","Cell RNA - AF22 [nTPM]":"30.3","Cell RNA - AN3-CA [nTPM]":"38.2","Cell RNA - ASC diff [nTPM]":"35.9","Cell RNA - ASC TERT1 [nTPM]":"29.0","Cell RNA - BEWO [nTPM]":"29.4","Cell RNA - BJ [nTPM]":"35.8","Cell RNA - BJ hTERT+ [nTPM]":"25.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.4","Cell RNA - CACO-2 [nTPM]":"25.2","Cell RNA - CAPAN-2 [nTPM]":"25.7","Cell RNA - Daudi [nTPM]":"25.8","Cell RNA - EFO-21 [nTPM]":"14.2","Cell RNA - fHDF\/TERT166 [nTPM]":"47.7","Cell RNA - GAMG [nTPM]":"23.8","Cell RNA - HaCaT [nTPM]":"25.5","Cell RNA - HAP1 [nTPM]":"45.0","Cell RNA - HBEC3-KT [nTPM]":"18.2","Cell RNA - HBF TERT88 [nTPM]":"36.0","Cell RNA - HDLM-2 [nTPM]":"23.3","Cell RNA - HEK 293 [nTPM]":"33.9","Cell RNA - HEL [nTPM]":"38.2","Cell RNA - HeLa [nTPM]":"22.8","Cell RNA - Hep G2 [nTPM]":"42.4","Cell RNA - HHSteC [nTPM]":"49.7","Cell RNA - HL-60 [nTPM]":"27.1","Cell RNA - HMC-1 [nTPM]":"21.4","Cell RNA - HSkMC [nTPM]":"32.4","Cell RNA - hTCEpi [nTPM]":"20.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.0","Cell RNA - hTERT-HME1 [nTPM]":"42.6","Cell RNA - hTERT-RPE1 [nTPM]":"48.0","Cell RNA - HUVEC TERT2 [nTPM]":"27.8","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"46.8","Cell RNA - Karpas-707 [nTPM]":"13.1","Cell RNA - LHCN-M2 [nTPM]":"37.2","Cell RNA - MCF7 [nTPM]":"24.7","Cell RNA - MOLT-4 [nTPM]":"23.2","Cell RNA - NB-4 [nTPM]":"24.2","Cell RNA - NTERA-2 [nTPM]":"30.1","Cell RNA - OE19 [nTPM]":"19.4","Cell RNA - PC-3 [nTPM]":"24.6","Cell RNA - REH [nTPM]":"21.8","Cell RNA - RH-30 [nTPM]":"18.6","Cell RNA - RPMI-8226 [nTPM]":"19.2","Cell RNA - RPTEC TERT1 [nTPM]":"30.1","Cell RNA - RT4 [nTPM]":"34.5","Cell RNA - SCLC-21H [nTPM]":"28.7","Cell RNA - SH-SY5Y [nTPM]":"25.2","Cell RNA - SiHa [nTPM]":"38.5","Cell RNA - SK-BR-3 [nTPM]":"49.3","Cell RNA - SK-MEL-30 [nTPM]":"24.7","Cell RNA - SuSa [nTPM]":"29.1","Cell RNA - T-47d [nTPM]":"30.9","Cell RNA - THP-1 [nTPM]":"16.5","Cell RNA - TIME [nTPM]":"34.9","Cell RNA - U-138 MG [nTPM]":"36.9","Cell RNA - U-2 OS [nTPM]":"21.6","Cell RNA - U-2197 [nTPM]":"30.4","Cell RNA - U-251 MG [nTPM]":"20.6","Cell RNA - U-266\/70 [nTPM]":"23.4","Cell RNA - U-266\/84 [nTPM]":"30.0","Cell RNA - U-698 [nTPM]":"22.5","Cell RNA - U-87 MG [nTPM]":"19.0","Cell RNA - U-937 [nTPM]":"20.9","Cell RNA - WM-115 [nTPM]":"23.5","Blood RNA - basophil [nTPM]":"4.5","Blood RNA - classical monocyte [nTPM]":"3.6","Blood RNA - eosinophil [nTPM]":"5.8","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"5.2","Blood RNA - memory B-cell [nTPM]":"5.1","Blood RNA - memory CD4 T-cell [nTPM]":"4.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"5.0","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"5.6","Blood RNA - non-classical monocyte [nTPM]":"6.4","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"2.8","Brain RNA - amygdala [nTPM]":"20.5","Brain RNA - basal ganglia [nTPM]":"21.9","Brain RNA - cerebellum [nTPM]":"22.8","Brain RNA - cerebral cortex [nTPM]":"30.3","Brain RNA - hippocampal formation [nTPM]":"20.5","Brain RNA - hypothalamus [nTPM]":"29.9","Brain RNA - medulla oblongata [nTPM]":"25.2","Brain RNA - midbrain [nTPM]":"26.0","Brain RNA - pons [nTPM]":"24.5","Brain RNA - spinal cord [nTPM]":"18.6","Brain RNA - thalamus [nTPM]":"22.7","Brain RNA - white matter [nTPM]":"25.8","Single Cell Type RNA - Adipocytes [nTPM]":"43.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"72.6","Single Cell Type RNA - Astrocytes [nTPM]":"175.3","Single Cell Type RNA - B-cells [nTPM]":"26.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.9","Single Cell Type RNA - Bipolar cells [nTPM]":"101.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"36.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"36.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"135.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.5","Single Cell Type RNA - dendritic cells [nTPM]":"28.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"26.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"87.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"72.2","Single Cell Type RNA - Endothelial cells [nTPM]":"43.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.4","Single Cell Type RNA - Erythroid cells [nTPM]":"34.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"146.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.4","Single Cell Type RNA - Fibroblasts [nTPM]":"40.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"50.3","Single Cell Type RNA - granulocytes [nTPM]":"23.5","Single Cell Type RNA - Granulosa cells [nTPM]":"67.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.5","Single Cell Type RNA - Hepatocytes [nTPM]":"38.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.5","Single Cell Type RNA - Horizontal cells [nTPM]":"65.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"171.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"35.9","Single Cell Type RNA - Langerhans cells [nTPM]":"35.9","Single Cell Type RNA - Late spermatids [nTPM]":"11.9","Single Cell Type RNA - Leydig cells [nTPM]":"65.6","Single Cell Type RNA - Macrophages [nTPM]":"30.6","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"106.8","Single Cell Type RNA - monocytes [nTPM]":"35.1","Single Cell Type RNA - Muller glia cells [nTPM]":"32.6","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"128.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"209.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.6","Single Cell Type RNA - Paneth cells [nTPM]":"16.0","Single Cell Type RNA - Peritubular cells [nTPM]":"47.4","Single Cell Type RNA - Plasma cells [nTPM]":"24.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"56.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"90.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.6","Single Cell Type RNA - Spermatocytes [nTPM]":"78.0","Single Cell Type RNA - Spermatogonia [nTPM]":"70.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.9","Single Cell Type RNA - T-cells [nTPM]":"27.4","Single Cell Type RNA - Theca cells [nTPM]":"68.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.5","Single Cell Type RNA - Urothelial cells [nTPM]":"42.2"},{"Gene":"ATXN3","Gene synonym":["ATX3","JOS","MJD","SCA3"],"Ensembl":"ENSG00000066427","Gene description":"Ataxin 3","Uniprot":["P54252"],"Chromosome":"14","Position":"92044496-92106621","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB021976","HPA024123","HPA069338"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB021976":null,"HPA024123":"AB_1845133","HPA069338":"AB_2686124"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.0","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"4.2","Tissue RNA - bone marrow [nTPM]":"9.9","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"5.0","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"7.3","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"6.0","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"9.6","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"6.2","Tissue RNA - midbrain [nTPM]":"5.7","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"6.0","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"12.9","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"9.3","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"9.8","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"8.0","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"8.6","Cell RNA - A549 [nTPM]":"16.7","Cell RNA - AF22 [nTPM]":"14.6","Cell RNA - AN3-CA [nTPM]":"13.6","Cell RNA - ASC diff [nTPM]":"20.9","Cell RNA - ASC TERT1 [nTPM]":"20.1","Cell RNA - BEWO [nTPM]":"28.4","Cell RNA - BJ [nTPM]":"9.7","Cell RNA - BJ hTERT+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.5","Cell RNA - CACO-2 [nTPM]":"12.3","Cell RNA - CAPAN-2 [nTPM]":"23.2","Cell RNA - Daudi [nTPM]":"17.6","Cell RNA - EFO-21 [nTPM]":"18.5","Cell RNA - fHDF\/TERT166 [nTPM]":"15.8","Cell RNA - GAMG [nTPM]":"14.1","Cell RNA - HaCaT [nTPM]":"14.6","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"21.0","Cell RNA - HBF TERT88 [nTPM]":"26.3","Cell RNA - HDLM-2 [nTPM]":"20.0","Cell RNA - HEK 293 [nTPM]":"3.5","Cell RNA - HEL [nTPM]":"7.4","Cell RNA - HeLa [nTPM]":"8.0","Cell RNA - Hep G2 [nTPM]":"18.2","Cell RNA - HHSteC [nTPM]":"17.3","Cell RNA - HL-60 [nTPM]":"13.5","Cell RNA - HMC-1 [nTPM]":"12.6","Cell RNA - HSkMC [nTPM]":"16.5","Cell RNA - hTCEpi [nTPM]":"18.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.9","Cell RNA - hTERT-HME1 [nTPM]":"21.8","Cell RNA - hTERT-RPE1 [nTPM]":"15.9","Cell RNA - HUVEC TERT2 [nTPM]":"18.7","Cell RNA - JURKAT [nTPM]":"19.4","Cell RNA - K-562 [nTPM]":"10.1","Cell RNA - Karpas-707 [nTPM]":"12.5","Cell RNA - LHCN-M2 [nTPM]":"18.2","Cell RNA - MCF7 [nTPM]":"33.1","Cell RNA - MOLT-4 [nTPM]":"14.0","Cell RNA - NB-4 [nTPM]":"11.9","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"28.5","Cell RNA - PC-3 [nTPM]":"13.6","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"27.0","Cell RNA - RPMI-8226 [nTPM]":"9.9","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"19.4","Cell RNA - SCLC-21H [nTPM]":"5.3","Cell RNA - SH-SY5Y [nTPM]":"8.8","Cell RNA - SiHa [nTPM]":"23.1","Cell RNA - SK-BR-3 [nTPM]":"9.5","Cell RNA - SK-MEL-30 [nTPM]":"13.3","Cell RNA - SuSa [nTPM]":"19.6","Cell RNA - T-47d [nTPM]":"18.1","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"10.0","Cell RNA - U-138 MG [nTPM]":"11.7","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"7.5","Cell RNA - U-251 MG [nTPM]":"5.2","Cell RNA - U-266\/70 [nTPM]":"10.8","Cell RNA - U-266\/84 [nTPM]":"19.8","Cell RNA - U-698 [nTPM]":"16.2","Cell RNA - U-87 MG [nTPM]":"8.3","Cell RNA - U-937 [nTPM]":"12.9","Cell RNA - WM-115 [nTPM]":"6.9","Blood RNA - basophil [nTPM]":"13.5","Blood RNA - classical monocyte [nTPM]":"14.3","Blood RNA - eosinophil [nTPM]":"10.8","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"16.5","Blood RNA - MAIT T-cell [nTPM]":"7.4","Blood RNA - memory B-cell [nTPM]":"7.7","Blood RNA - memory CD4 T-cell [nTPM]":"7.0","Blood RNA - memory CD8 T-cell [nTPM]":"6.9","Blood RNA - myeloid DC [nTPM]":"16.2","Blood RNA - naive B-cell [nTPM]":"10.6","Blood RNA - naive CD4 T-cell [nTPM]":"7.8","Blood RNA - naive CD8 T-cell [nTPM]":"8.8","Blood RNA - neutrophil [nTPM]":"12.2","Blood RNA - NK-cell [nTPM]":"8.7","Blood RNA - non-classical monocyte [nTPM]":"23.0","Blood RNA - plasmacytoid DC [nTPM]":"9.3","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"6.3","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"4.2","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"5.0","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"6.2","Brain RNA - midbrain [nTPM]":"5.7","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"55.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"33.6","Single Cell Type RNA - B-cells [nTPM]":"27.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"35.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"20.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.3","Single Cell Type RNA - dendritic cells [nTPM]":"31.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"25.8","Single Cell Type RNA - Early spermatids [nTPM]":"19.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.9","Single Cell Type RNA - Endothelial cells [nTPM]":"53.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.1","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.8","Single Cell Type RNA - Fibroblasts [nTPM]":"34.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.5","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"25.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"21.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.4","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"35.1","Single Cell Type RNA - Langerhans cells [nTPM]":"27.2","Single Cell Type RNA - Late spermatids [nTPM]":"26.8","Single Cell Type RNA - Leydig cells [nTPM]":"67.7","Single Cell Type RNA - Macrophages [nTPM]":"30.0","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"48.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.4","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"51.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.6","Single Cell Type RNA - Paneth cells [nTPM]":"16.1","Single Cell Type RNA - Peritubular cells [nTPM]":"65.1","Single Cell Type RNA - Plasma cells [nTPM]":"20.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"46.7","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"51.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"38.2","Single Cell Type RNA - Spermatocytes [nTPM]":"39.1","Single Cell Type RNA - Spermatogonia [nTPM]":"57.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - T-cells [nTPM]":"28.8","Single Cell Type RNA - Theca cells [nTPM]":"24.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.9","Single Cell Type RNA - Urothelial cells [nTPM]":"28.2"},{"Gene":"ATXN7","Gene synonym":["ADCAII","OPCA3","SCA7","SGF73"],"Ensembl":"ENSG00000163635","Gene description":"Ataxin 7","Uniprot":["O15265"],"Chromosome":"3","Position":"63863155-64003462","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"102.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"15.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034989"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA034989":"AB_10602596"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.22e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.5","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"4.5","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"4.1","Tissue RNA - bone marrow [nTPM]":"24.4","Tissue RNA - breast [nTPM]":"7.1","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"7.4","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"8.4","Tissue RNA - lung [nTPM]":"9.0","Tissue RNA - lymph node [nTPM]":"12.7","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"3.3","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"21.0","Tissue RNA - parathyroid gland [nTPM]":"10.9","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"8.8","Tissue RNA - retina [nTPM]":"16.3","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"9.3","Tissue RNA - small intestine [nTPM]":"9.2","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"10.6","Tissue RNA - stomach 1 [nTPM]":"8.4","Tissue RNA - testis [nTPM]":"15.0","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"16.5","Tissue RNA - thyroid gland [nTPM]":"7.5","Tissue RNA - tongue [nTPM]":"8.7","Tissue RNA - tonsil [nTPM]":"11.7","Tissue RNA - urinary bladder [nTPM]":"7.4","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"8.4","Cell RNA - A549 [nTPM]":"5.7","Cell RNA - AF22 [nTPM]":"8.1","Cell RNA - AN3-CA [nTPM]":"7.2","Cell RNA - ASC diff [nTPM]":"8.5","Cell RNA - ASC TERT1 [nTPM]":"11.3","Cell RNA - BEWO [nTPM]":"9.5","Cell RNA - BJ [nTPM]":"6.5","Cell RNA - BJ hTERT+ [nTPM]":"9.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.5","Cell RNA - CACO-2 [nTPM]":"8.9","Cell RNA - CAPAN-2 [nTPM]":"8.7","Cell RNA - Daudi [nTPM]":"12.5","Cell RNA - EFO-21 [nTPM]":"3.1","Cell RNA - fHDF\/TERT166 [nTPM]":"9.0","Cell RNA - GAMG [nTPM]":"12.5","Cell RNA - HaCaT [nTPM]":"6.5","Cell RNA - HAP1 [nTPM]":"9.6","Cell RNA - HBEC3-KT [nTPM]":"9.1","Cell RNA - HBF TERT88 [nTPM]":"11.9","Cell RNA - HDLM-2 [nTPM]":"22.8","Cell RNA - HEK 293 [nTPM]":"4.9","Cell RNA - HEL [nTPM]":"16.1","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"4.2","Cell RNA - HHSteC [nTPM]":"6.4","Cell RNA - HL-60 [nTPM]":"8.5","Cell RNA - HMC-1 [nTPM]":"17.7","Cell RNA - HSkMC [nTPM]":"7.9","Cell RNA - hTCEpi [nTPM]":"9.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.7","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"9.0","Cell RNA - HUVEC TERT2 [nTPM]":"8.4","Cell RNA - JURKAT [nTPM]":"13.3","Cell RNA - K-562 [nTPM]":"6.3","Cell RNA - Karpas-707 [nTPM]":"26.2","Cell RNA - LHCN-M2 [nTPM]":"7.7","Cell RNA - MCF7 [nTPM]":"25.8","Cell RNA - MOLT-4 [nTPM]":"12.7","Cell RNA - NB-4 [nTPM]":"6.8","Cell RNA - NTERA-2 [nTPM]":"5.5","Cell RNA - OE19 [nTPM]":"5.7","Cell RNA - PC-3 [nTPM]":"3.0","Cell RNA - REH [nTPM]":"9.1","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"10.1","Cell RNA - RPTEC TERT1 [nTPM]":"6.1","Cell RNA - RT4 [nTPM]":"11.0","Cell RNA - SCLC-21H [nTPM]":"3.1","Cell RNA - SH-SY5Y [nTPM]":"5.6","Cell RNA - SiHa [nTPM]":"13.2","Cell RNA - SK-BR-3 [nTPM]":"9.4","Cell RNA - SK-MEL-30 [nTPM]":"10.8","Cell RNA - SuSa [nTPM]":"6.4","Cell RNA - T-47d [nTPM]":"5.1","Cell RNA - THP-1 [nTPM]":"12.2","Cell RNA - TIME [nTPM]":"11.9","Cell RNA - U-138 MG [nTPM]":"11.4","Cell RNA - U-2 OS [nTPM]":"12.0","Cell RNA - U-2197 [nTPM]":"12.7","Cell RNA - U-251 MG [nTPM]":"12.9","Cell RNA - U-266\/70 [nTPM]":"12.9","Cell RNA - U-266\/84 [nTPM]":"13.2","Cell RNA - U-698 [nTPM]":"10.3","Cell RNA - U-87 MG [nTPM]":"10.3","Cell RNA - U-937 [nTPM]":"11.6","Cell RNA - WM-115 [nTPM]":"9.4","Blood RNA - basophil [nTPM]":"15.8","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.2","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"6.2","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"4.5","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"6.2","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"4.5","Brain RNA - basal ganglia [nTPM]":"4.1","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"3.3","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"34.6","Single Cell Type RNA - B-cells [nTPM]":"17.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"43.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.6","Single Cell Type RNA - Bipolar cells [nTPM]":"73.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"17.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"102.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - dendritic cells [nTPM]":"21.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.8","Single Cell Type RNA - Early spermatids [nTPM]":"17.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"16.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.4","Single Cell Type RNA - Erythroid cells [nTPM]":"29.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"81.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.6","Single Cell Type RNA - Fibroblasts [nTPM]":"16.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.5","Single Cell Type RNA - granulocytes [nTPM]":"14.7","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"22.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.2","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"67.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"34.6","Single Cell Type RNA - Langerhans cells [nTPM]":"30.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.5","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"20.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"64.6","Single Cell Type RNA - monocytes [nTPM]":"33.5","Single Cell Type RNA - Muller glia cells [nTPM]":"24.5","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"60.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.5","Single Cell Type RNA - Paneth cells [nTPM]":"28.5","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"14.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"70.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.6","Single Cell Type RNA - Spermatocytes [nTPM]":"14.8","Single Cell Type RNA - Spermatogonia [nTPM]":"15.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"46.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"61.2","Single Cell Type RNA - T-cells [nTPM]":"41.5","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.1","Single Cell Type RNA - Urothelial cells [nTPM]":"38.6"},{"Gene":"B2M","Gene synonym":[],"Ensembl":"ENSG00000166710","Gene description":"Beta-2-microglobulin","Uniprot":["P61769"],"Chromosome":"15","Position":"44711487-44718851","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":["Amyloidosis","Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"31919.3","NK-cells":"24726.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002572","HPA006361"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1790000000,"Blood concentration - Conc. blood MS [pg\/L]":"2100000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB002572":"AB_563434","HPA006361":"AB_1078278"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"3160.2","Tissue RNA - adrenal gland [nTPM]":"3214.7","Tissue RNA - amygdala [nTPM]":"697.6","Tissue RNA - appendix [nTPM]":"5686.5","Tissue RNA - basal ganglia [nTPM]":"705.1","Tissue RNA - bone marrow [nTPM]":"7839.2","Tissue RNA - breast [nTPM]":"2606.9","Tissue RNA - cerebellum [nTPM]":"711.8","Tissue RNA - cerebral cortex [nTPM]":"1145.0","Tissue RNA - cervix [nTPM]":"2539.9","Tissue RNA - choroid plexus [nTPM]":"789.6","Tissue RNA - colon [nTPM]":"5139.0","Tissue RNA - duodenum [nTPM]":"5180.7","Tissue RNA - endometrium 1 [nTPM]":"2192.2","Tissue RNA - epididymis [nTPM]":"1735.6","Tissue RNA - esophagus [nTPM]":"2283.9","Tissue RNA - fallopian tube [nTPM]":"1648.3","Tissue RNA - gallbladder [nTPM]":"4948.8","Tissue RNA - heart muscle [nTPM]":"2327.2","Tissue RNA - hippocampal formation [nTPM]":"651.0","Tissue RNA - hypothalamus [nTPM]":"769.9","Tissue RNA - kidney [nTPM]":"2462.6","Tissue RNA - liver [nTPM]":"6206.2","Tissue RNA - lung [nTPM]":"6159.2","Tissue RNA - lymph node [nTPM]":"9311.8","Tissue RNA - medulla oblongata [nTPM]":"889.5","Tissue RNA - midbrain [nTPM]":"763.2","Tissue RNA - ovary [nTPM]":"1945.7","Tissue RNA - pancreas [nTPM]":"1310.9","Tissue RNA - parathyroid gland [nTPM]":"1940.5","Tissue RNA - pituitary gland [nTPM]":"318.4","Tissue RNA - placenta [nTPM]":"3502.0","Tissue RNA - pons [nTPM]":"815.3","Tissue RNA - prostate [nTPM]":"2345.0","Tissue RNA - rectum [nTPM]":"5593.5","Tissue RNA - retina [nTPM]":"139.3","Tissue RNA - salivary gland [nTPM]":"5657.1","Tissue RNA - seminal vesicle [nTPM]":"1784.5","Tissue RNA - skeletal muscle [nTPM]":"931.7","Tissue RNA - skin 1 [nTPM]":"3015.6","Tissue RNA - small intestine [nTPM]":"5693.3","Tissue RNA - smooth muscle [nTPM]":"2545.3","Tissue RNA - spinal cord [nTPM]":"838.3","Tissue RNA - spleen [nTPM]":"7896.1","Tissue RNA - stomach 1 [nTPM]":"4878.2","Tissue RNA - testis [nTPM]":"615.6","Tissue RNA - thalamus [nTPM]":"771.9","Tissue RNA - thymus [nTPM]":"4217.4","Tissue RNA - thyroid gland [nTPM]":"2340.8","Tissue RNA - tongue [nTPM]":"2026.5","Tissue RNA - tonsil [nTPM]":"5333.4","Tissue RNA - urinary bladder [nTPM]":"5753.1","Tissue RNA - vagina [nTPM]":"549.4","Tissue RNA - white matter [nTPM]":"909.5","Cell RNA - A-431 [nTPM]":"1735.4","Cell RNA - A549 [nTPM]":"378.9","Cell RNA - AF22 [nTPM]":"226.0","Cell RNA - AN3-CA [nTPM]":"633.6","Cell RNA - ASC diff [nTPM]":"4348.7","Cell RNA - ASC TERT1 [nTPM]":"4719.4","Cell RNA - BEWO [nTPM]":"1662.5","Cell RNA - BJ [nTPM]":"2045.5","Cell RNA - BJ hTERT+ [nTPM]":"4961.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3609.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6561.4","Cell RNA - CACO-2 [nTPM]":"425.3","Cell RNA - CAPAN-2 [nTPM]":"5417.9","Cell RNA - Daudi [nTPM]":"554.8","Cell RNA - EFO-21 [nTPM]":"2567.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1948.8","Cell RNA - GAMG [nTPM]":"2410.2","Cell RNA - HaCaT [nTPM]":"2537.0","Cell RNA - HAP1 [nTPM]":"497.2","Cell RNA - HBEC3-KT [nTPM]":"878.7","Cell RNA - HBF TERT88 [nTPM]":"1226.2","Cell RNA - HDLM-2 [nTPM]":"4762.2","Cell RNA - HEK 293 [nTPM]":"435.9","Cell RNA - HEL [nTPM]":"2956.9","Cell RNA - HeLa [nTPM]":"2263.6","Cell RNA - Hep G2 [nTPM]":"600.3","Cell RNA - HHSteC [nTPM]":"3609.3","Cell RNA - HL-60 [nTPM]":"2074.5","Cell RNA - HMC-1 [nTPM]":"3328.6","Cell RNA - HSkMC [nTPM]":"2735.9","Cell RNA - hTCEpi [nTPM]":"609.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1075.7","Cell RNA - hTERT-HME1 [nTPM]":"1044.4","Cell RNA - hTERT-RPE1 [nTPM]":"2442.6","Cell RNA - HUVEC TERT2 [nTPM]":"1884.1","Cell RNA - JURKAT [nTPM]":"965.4","Cell RNA - K-562 [nTPM]":"611.9","Cell RNA - Karpas-707 [nTPM]":"3649.1","Cell RNA - LHCN-M2 [nTPM]":"2195.5","Cell RNA - MCF7 [nTPM]":"476.9","Cell RNA - MOLT-4 [nTPM]":"1518.4","Cell RNA - NB-4 [nTPM]":"3213.8","Cell RNA - NTERA-2 [nTPM]":"206.5","Cell RNA - OE19 [nTPM]":"629.8","Cell RNA - PC-3 [nTPM]":"1014.3","Cell RNA - REH [nTPM]":"2240.2","Cell RNA - RH-30 [nTPM]":"1926.6","Cell RNA - RPMI-8226 [nTPM]":"4789.2","Cell RNA - RPTEC TERT1 [nTPM]":"2425.5","Cell RNA - RT4 [nTPM]":"3486.4","Cell RNA - SCLC-21H [nTPM]":"254.1","Cell RNA - SH-SY5Y [nTPM]":"179.1","Cell RNA - SiHa [nTPM]":"1288.4","Cell RNA - SK-BR-3 [nTPM]":"1571.2","Cell RNA - SK-MEL-30 [nTPM]":"1338.5","Cell RNA - SuSa [nTPM]":"394.3","Cell RNA - T-47d [nTPM]":"655.3","Cell RNA - THP-1 [nTPM]":"6180.6","Cell RNA - TIME [nTPM]":"2548.7","Cell RNA - U-138 MG [nTPM]":"4531.4","Cell RNA - U-2 OS [nTPM]":"676.5","Cell RNA - U-2197 [nTPM]":"5389.2","Cell RNA - U-251 MG [nTPM]":"2193.3","Cell RNA - U-266\/70 [nTPM]":"4771.7","Cell RNA - U-266\/84 [nTPM]":"7118.6","Cell RNA - U-698 [nTPM]":"1683.1","Cell RNA - U-87 MG [nTPM]":"5384.6","Cell RNA - U-937 [nTPM]":"3783.6","Cell RNA - WM-115 [nTPM]":"2567.3","Blood RNA - basophil [nTPM]":"48105.4","Blood RNA - classical monocyte [nTPM]":"18117.1","Blood RNA - eosinophil [nTPM]":"33178.9","Blood RNA - gdT-cell [nTPM]":"20639.1","Blood RNA - intermediate monocyte [nTPM]":"17775.0","Blood RNA - MAIT T-cell [nTPM]":"20836.8","Blood RNA - memory B-cell [nTPM]":"15768.0","Blood RNA - memory CD4 T-cell [nTPM]":"23783.0","Blood RNA - memory CD8 T-cell [nTPM]":"22245.1","Blood RNA - myeloid DC [nTPM]":"9978.8","Blood RNA - naive B-cell [nTPM]":"11988.4","Blood RNA - naive CD4 T-cell [nTPM]":"17122.9","Blood RNA - naive CD8 T-cell [nTPM]":"22791.8","Blood RNA - neutrophil [nTPM]":"50453.6","Blood RNA - NK-cell [nTPM]":"18779.6","Blood RNA - non-classical monocyte [nTPM]":"19034.9","Blood RNA - plasmacytoid DC [nTPM]":"12052.6","Blood RNA - T-reg [nTPM]":"29659.1","Blood RNA - total PBMC [nTPM]":"56957.2","Brain RNA - amygdala [nTPM]":"697.6","Brain RNA - basal ganglia [nTPM]":"705.1","Brain RNA - cerebellum [nTPM]":"711.8","Brain RNA - cerebral cortex [nTPM]":"1145.0","Brain RNA - hippocampal formation [nTPM]":"651.0","Brain RNA - hypothalamus [nTPM]":"769.9","Brain RNA - medulla oblongata [nTPM]":"889.5","Brain RNA - midbrain [nTPM]":"763.2","Brain RNA - pons [nTPM]":"815.3","Brain RNA - spinal cord [nTPM]":"838.3","Brain RNA - thalamus [nTPM]":"771.9","Brain RNA - white matter [nTPM]":"909.5","Single Cell Type RNA - Adipocytes [nTPM]":"12048.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3387.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3505.1","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"8472.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7843.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3197.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8420.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1628.8","Single Cell Type RNA - Bipolar cells [nTPM]":"33.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2399.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2015.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1068.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"3593.1","Single Cell Type RNA - Club cells [nTPM]":"5347.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"2100.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1354.6","Single Cell Type RNA - dendritic cells [nTPM]":"14028.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"8753.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1038.9","Single Cell Type RNA - Ductal cells [nTPM]":"13898.6","Single Cell Type RNA - Early spermatids [nTPM]":"43.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2073.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2414.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8385.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2266.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2087.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9034.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4397.5","Single Cell Type RNA - Fibroblasts [nTPM]":"3691.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1981.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2282.2","Single Cell Type RNA - granulocytes [nTPM]":"3029.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1270.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6835.7","Single Cell Type RNA - Hepatocytes [nTPM]":"3832.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"11985.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5982.6","Single Cell Type RNA - Ionocytes [nTPM]":"8701.4","Single Cell Type RNA - Kupffer cells [nTPM]":"12536.8","Single Cell Type RNA - Langerhans cells [nTPM]":"14507.0","Single Cell Type RNA - Late spermatids [nTPM]":"158.8","Single Cell Type RNA - Leydig cells [nTPM]":"3018.0","Single Cell Type RNA - Macrophages [nTPM]":"10687.9","Single Cell Type RNA - Melanocytes [nTPM]":"6744.8","Single Cell Type RNA - Microglial cells [nTPM]":"368.2","Single Cell Type RNA - monocytes [nTPM]":"31919.3","Single Cell Type RNA - Muller glia cells [nTPM]":"322.0","Single Cell Type RNA - NK-cells [nTPM]":"24726.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"95.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"129.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10115.7","Single Cell Type RNA - Paneth cells [nTPM]":"7085.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1688.8","Single Cell Type RNA - Plasma cells [nTPM]":"11026.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5300.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18327.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3122.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8367.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"52.5","Single Cell Type RNA - Sertoli cells [nTPM]":"4016.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2055.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4107.1","Single Cell Type RNA - Spermatocytes [nTPM]":"64.2","Single Cell Type RNA - Spermatogonia [nTPM]":"72.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1541.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8619.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"804.8","Single Cell Type RNA - T-cells [nTPM]":"14266.2","Single Cell Type RNA - Theca cells [nTPM]":"3229.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3063.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8248.6"},{"Gene":"B4GALNT1","Gene synonym":["beta1-4GalNAc-T","GALGT","SPG26"],"Ensembl":"ENSG00000135454","Gene description":"Beta-1,4-N-acetyl-galactosaminyltransferase 1","Uniprot":["Q00973"],"Chromosome":"12","Position":"57623409-57633239","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"61.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"10.0","Excitatory neurons":"22.0","Horizontal cells":"21.9","Inhibitory neurons":"13.4","Smooth muscle cells":"7.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"10.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"67.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008968"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"35000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008968":"AB_1078253"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.18e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-4"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"26.9","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"29.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"29.3","Tissue RNA - cerebral cortex [nTPM]":"61.1","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"34.9","Tissue RNA - hypothalamus [nTPM]":"21.9","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"16.7","Tissue RNA - midbrain [nTPM]":"11.8","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"20.5","Tissue RNA - prostate [nTPM]":"2.6","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"9.5","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"19.1","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"29.9","Cell RNA - A-431 [nTPM]":"7.5","Cell RNA - A549 [nTPM]":"38.2","Cell RNA - AF22 [nTPM]":"18.2","Cell RNA - AN3-CA [nTPM]":"38.7","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"3.0","Cell RNA - BJ hTERT+ [nTPM]":"11.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.5","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"21.9","Cell RNA - Daudi [nTPM]":"3.0","Cell RNA - EFO-21 [nTPM]":"47.9","Cell RNA - fHDF\/TERT166 [nTPM]":"13.2","Cell RNA - GAMG [nTPM]":"35.9","Cell RNA - HaCaT [nTPM]":"3.3","Cell RNA - HAP1 [nTPM]":"15.3","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"5.2","Cell RNA - HDLM-2 [nTPM]":"67.4","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"10.1","Cell RNA - Hep G2 [nTPM]":"9.9","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"3.1","Cell RNA - HMC-1 [nTPM]":"4.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.0","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"6.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"11.4","Cell RNA - K-562 [nTPM]":"8.7","Cell RNA - Karpas-707 [nTPM]":"34.8","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"13.5","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"27.1","Cell RNA - RPMI-8226 [nTPM]":"8.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"34.9","Cell RNA - SH-SY5Y [nTPM]":"12.3","Cell RNA - SiHa [nTPM]":"3.1","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"7.0","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"22.8","Cell RNA - U-2 OS [nTPM]":"28.1","Cell RNA - U-2197 [nTPM]":"24.0","Cell RNA - U-251 MG [nTPM]":"26.1","Cell RNA - U-266\/70 [nTPM]":"37.0","Cell RNA - U-266\/84 [nTPM]":"34.0","Cell RNA - U-698 [nTPM]":"2.6","Cell RNA - U-87 MG [nTPM]":"28.9","Cell RNA - U-937 [nTPM]":"2.3","Cell RNA - WM-115 [nTPM]":"45.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"26.9","Brain RNA - basal ganglia [nTPM]":"29.7","Brain RNA - cerebellum [nTPM]":"29.3","Brain RNA - cerebral cortex [nTPM]":"61.1","Brain RNA - hippocampal formation [nTPM]":"34.9","Brain RNA - hypothalamus [nTPM]":"21.9","Brain RNA - medulla oblongata [nTPM]":"16.7","Brain RNA - midbrain [nTPM]":"11.8","Brain RNA - pons [nTPM]":"20.5","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"19.1","Brain RNA - white matter [nTPM]":"29.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"2.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"BBS2","Gene synonym":["BBS"],"Ensembl":"ENSG00000125124","Gene description":"Bardet-Biedl syndrome 2","Uniprot":["Q9BXC9"],"Chromosome":"16","Position":"56466836-56520087","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Protein transport","Sensory transduction","Transport","Vision"],"Molecular function":null,"Disease involvement":["Bardet-Biedl syndrome","Ciliopathy","Disease variant","Mental retardation","Obesity","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"144.3","Oligodendrocytes":"97.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041315"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041315":"AB_10960892"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.83e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.3","Tissue RNA - adrenal gland [nTPM]":"78.3","Tissue RNA - amygdala [nTPM]":"90.1","Tissue RNA - appendix [nTPM]":"9.3","Tissue RNA - basal ganglia [nTPM]":"102.5","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"29.5","Tissue RNA - cerebellum [nTPM]":"93.2","Tissue RNA - cerebral cortex [nTPM]":"117.7","Tissue RNA - cervix [nTPM]":"31.1","Tissue RNA - choroid plexus [nTPM]":"80.7","Tissue RNA - colon [nTPM]":"23.6","Tissue RNA - duodenum [nTPM]":"13.5","Tissue RNA - endometrium 1 [nTPM]":"25.9","Tissue RNA - epididymis [nTPM]":"47.1","Tissue RNA - esophagus [nTPM]":"23.2","Tissue RNA - fallopian tube [nTPM]":"32.7","Tissue RNA - gallbladder [nTPM]":"21.6","Tissue RNA - heart muscle [nTPM]":"32.8","Tissue RNA - hippocampal formation [nTPM]":"87.5","Tissue RNA - hypothalamus [nTPM]":"89.4","Tissue RNA - kidney [nTPM]":"41.7","Tissue RNA - liver [nTPM]":"13.2","Tissue RNA - lung [nTPM]":"20.2","Tissue RNA - lymph node [nTPM]":"18.4","Tissue RNA - medulla oblongata [nTPM]":"94.4","Tissue RNA - midbrain [nTPM]":"90.4","Tissue RNA - ovary [nTPM]":"40.7","Tissue RNA - pancreas [nTPM]":"15.7","Tissue RNA - parathyroid gland [nTPM]":"53.7","Tissue RNA - pituitary gland [nTPM]":"38.1","Tissue RNA - placenta [nTPM]":"16.1","Tissue RNA - pons [nTPM]":"96.2","Tissue RNA - prostate [nTPM]":"26.9","Tissue RNA - rectum [nTPM]":"16.9","Tissue RNA - retina [nTPM]":"86.5","Tissue RNA - salivary gland [nTPM]":"20.0","Tissue RNA - seminal vesicle [nTPM]":"27.0","Tissue RNA - skeletal muscle [nTPM]":"41.5","Tissue RNA - skin 1 [nTPM]":"36.4","Tissue RNA - small intestine [nTPM]":"17.7","Tissue RNA - smooth muscle [nTPM]":"24.0","Tissue RNA - spinal cord [nTPM]":"89.4","Tissue RNA - spleen [nTPM]":"21.0","Tissue RNA - stomach 1 [nTPM]":"17.2","Tissue RNA - testis [nTPM]":"28.6","Tissue RNA - thalamus [nTPM]":"91.5","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"28.1","Tissue RNA - tongue [nTPM]":"50.8","Tissue RNA - tonsil [nTPM]":"16.2","Tissue RNA - urinary bladder [nTPM]":"21.1","Tissue RNA - vagina [nTPM]":"29.7","Tissue RNA - white matter [nTPM]":"107.9","Cell RNA - A-431 [nTPM]":"22.3","Cell RNA - A549 [nTPM]":"19.7","Cell RNA - AF22 [nTPM]":"29.6","Cell RNA - AN3-CA [nTPM]":"29.9","Cell RNA - ASC diff [nTPM]":"47.1","Cell RNA - ASC TERT1 [nTPM]":"56.9","Cell RNA - BEWO [nTPM]":"17.4","Cell RNA - BJ [nTPM]":"10.7","Cell RNA - BJ hTERT+ [nTPM]":"40.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.8","Cell RNA - CACO-2 [nTPM]":"11.0","Cell RNA - CAPAN-2 [nTPM]":"18.0","Cell RNA - Daudi [nTPM]":"22.1","Cell RNA - EFO-21 [nTPM]":"17.6","Cell RNA - fHDF\/TERT166 [nTPM]":"24.3","Cell RNA - GAMG [nTPM]":"19.0","Cell RNA - HaCaT [nTPM]":"25.3","Cell RNA - HAP1 [nTPM]":"11.7","Cell RNA - HBEC3-KT [nTPM]":"36.4","Cell RNA - HBF TERT88 [nTPM]":"36.0","Cell RNA - HDLM-2 [nTPM]":"4.9","Cell RNA - HEK 293 [nTPM]":"26.3","Cell RNA - HEL [nTPM]":"10.4","Cell RNA - HeLa [nTPM]":"19.4","Cell RNA - Hep G2 [nTPM]":"28.1","Cell RNA - HHSteC [nTPM]":"30.7","Cell RNA - HL-60 [nTPM]":"12.1","Cell RNA - HMC-1 [nTPM]":"11.4","Cell RNA - HSkMC [nTPM]":"35.4","Cell RNA - hTCEpi [nTPM]":"26.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.3","Cell RNA - hTERT-HME1 [nTPM]":"16.8","Cell RNA - hTERT-RPE1 [nTPM]":"49.0","Cell RNA - HUVEC TERT2 [nTPM]":"50.0","Cell RNA - JURKAT [nTPM]":"16.7","Cell RNA - K-562 [nTPM]":"4.7","Cell RNA - Karpas-707 [nTPM]":"2.7","Cell RNA - LHCN-M2 [nTPM]":"28.9","Cell RNA - MCF7 [nTPM]":"15.2","Cell RNA - MOLT-4 [nTPM]":"16.8","Cell RNA - NB-4 [nTPM]":"14.1","Cell RNA - NTERA-2 [nTPM]":"7.9","Cell RNA - OE19 [nTPM]":"14.9","Cell RNA - PC-3 [nTPM]":"32.7","Cell RNA - REH [nTPM]":"12.9","Cell RNA - RH-30 [nTPM]":"8.3","Cell RNA - RPMI-8226 [nTPM]":"25.7","Cell RNA - RPTEC TERT1 [nTPM]":"36.2","Cell RNA - RT4 [nTPM]":"18.1","Cell RNA - SCLC-21H [nTPM]":"20.7","Cell RNA - SH-SY5Y [nTPM]":"15.5","Cell RNA - SiHa [nTPM]":"51.9","Cell RNA - SK-BR-3 [nTPM]":"20.2","Cell RNA - SK-MEL-30 [nTPM]":"27.8","Cell RNA - SuSa [nTPM]":"23.7","Cell RNA - T-47d [nTPM]":"17.2","Cell RNA - THP-1 [nTPM]":"14.3","Cell RNA - TIME [nTPM]":"43.3","Cell RNA - U-138 MG [nTPM]":"18.3","Cell RNA - U-2 OS [nTPM]":"11.6","Cell RNA - U-2197 [nTPM]":"8.3","Cell RNA - U-251 MG [nTPM]":"5.7","Cell RNA - U-266\/70 [nTPM]":"10.4","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"17.1","Cell RNA - U-87 MG [nTPM]":"31.6","Cell RNA - U-937 [nTPM]":"10.5","Cell RNA - WM-115 [nTPM]":"13.7","Blood RNA - basophil [nTPM]":"9.9","Blood RNA - classical monocyte [nTPM]":"9.6","Blood RNA - eosinophil [nTPM]":"24.5","Blood RNA - gdT-cell [nTPM]":"15.6","Blood RNA - intermediate monocyte [nTPM]":"13.6","Blood RNA - MAIT T-cell [nTPM]":"15.8","Blood RNA - memory B-cell [nTPM]":"11.4","Blood RNA - memory CD4 T-cell [nTPM]":"18.7","Blood RNA - memory CD8 T-cell [nTPM]":"20.6","Blood RNA - myeloid DC [nTPM]":"11.8","Blood RNA - naive B-cell [nTPM]":"12.4","Blood RNA - naive CD4 T-cell [nTPM]":"24.4","Blood RNA - naive CD8 T-cell [nTPM]":"23.2","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"22.4","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"16.4","Blood RNA - total PBMC [nTPM]":"14.0","Brain RNA - amygdala [nTPM]":"90.1","Brain RNA - basal ganglia [nTPM]":"102.5","Brain RNA - cerebellum [nTPM]":"93.2","Brain RNA - cerebral cortex [nTPM]":"117.7","Brain RNA - hippocampal formation [nTPM]":"87.5","Brain RNA - hypothalamus [nTPM]":"89.4","Brain RNA - medulla oblongata [nTPM]":"94.4","Brain RNA - midbrain [nTPM]":"90.4","Brain RNA - pons [nTPM]":"96.2","Brain RNA - spinal cord [nTPM]":"89.4","Brain RNA - thalamus [nTPM]":"91.5","Brain RNA - white matter [nTPM]":"107.9","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.3","Single Cell Type RNA - Astrocytes [nTPM]":"144.3","Single Cell Type RNA - B-cells [nTPM]":"9.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"21.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"18.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.3","Single Cell Type RNA - dendritic cells [nTPM]":"6.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.1","Single Cell Type RNA - Early spermatids [nTPM]":"21.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"41.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"18.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.9","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"27.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.1","Single Cell Type RNA - Hepatocytes [nTPM]":"6.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.2","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.3","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"11.3","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"19.7","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"8.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"9.0","Single Cell Type RNA - Muller glia cells [nTPM]":"26.6","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"71.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"97.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.0","Single Cell Type RNA - Paneth cells [nTPM]":"10.4","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"4.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"56.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.0","Single Cell Type RNA - Spermatocytes [nTPM]":"18.4","Single Cell Type RNA - Spermatogonia [nTPM]":"20.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - T-cells [nTPM]":"10.5","Single Cell Type RNA - Theca cells [nTPM]":"59.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.0"},{"Gene":"BDNF","Gene synonym":[],"Ensembl":"ENSG00000176697","Gene description":"Brain derived neurotrophic factor","Uniprot":["P23560"],"Chromosome":"11","Position":"27654893-27722058","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"38.5","Bipolar cells":"13.8","Cardiomyocytes":"9.1","Excitatory neurons":"22.3","Smooth muscle cells":"25.8","Theca cells":"9.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"36.6","BJ hTERT+ SV40 Large T+":"28.0","BJ hTERT+ SV40 Large T+ RasG12V":"20.9","HBF TERT88":"26.5","U-138 MG":"37.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009564","HPA031440","HPA056104"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Mitochondria"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":16000000,"Blood concentration - Conc. blood MS [pg\/L]":"24000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nuclear speckles","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB009564":"AB_2064213","HPA031440":"AB_2673883","HPA056104":"AB_2683038"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"3.6","Tissue RNA - hippocampal formation [nTPM]":"8.2","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"2.5","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.7","Cell RNA - ASC TERT1 [nTPM]":"2.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"36.6","Cell RNA - BJ hTERT+ [nTPM]":"7.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.9","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"4.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"11.8","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"26.5","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"3.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"17.4","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"9.2","Cell RNA - hTCEpi [nTPM]":"4.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.8","Cell RNA - hTERT-HME1 [nTPM]":"3.7","Cell RNA - hTERT-RPE1 [nTPM]":"18.1","Cell RNA - HUVEC TERT2 [nTPM]":"1.3","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"4.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"2.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"7.8","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"11.0","Cell RNA - U-138 MG [nTPM]":"37.6","Cell RNA - U-2 OS [nTPM]":"6.9","Cell RNA - U-2197 [nTPM]":"14.4","Cell RNA - U-251 MG [nTPM]":"9.2","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"14.1","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"8.2","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"2.5","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"13.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"9.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"BDP1","Gene synonym":["HSA238520","KIAA1241","KIAA1689","TAF3B1","TFC5","TFIIIB150","TFIIIB90","TFNR"],"Ensembl":"ENSG00000145734","Gene description":"B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB","Uniprot":["A6H8Y1"],"Chromosome":"5","Position":"71455651-71567820","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"TIME":"16.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064166","HPA077984"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA064166":null,"HPA077984":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.5","Tissue RNA - adrenal gland [nTPM]":"2.7","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"2.7","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"5.8","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"1.9","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"2.8","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"10.1","Cell RNA - AN3-CA [nTPM]":"3.1","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"5.0","Cell RNA - BEWO [nTPM]":"7.7","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"9.4","Cell RNA - fHDF\/TERT166 [nTPM]":"4.0","Cell RNA - GAMG [nTPM]":"11.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"3.2","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"11.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"7.0","Cell RNA - Hep G2 [nTPM]":"3.1","Cell RNA - HHSteC [nTPM]":"4.2","Cell RNA - HL-60 [nTPM]":"4.4","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"5.9","Cell RNA - hTERT-RPE1 [nTPM]":"5.4","Cell RNA - HUVEC TERT2 [nTPM]":"7.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"12.7","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"5.0","Cell RNA - MCF7 [nTPM]":"3.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"10.5","Cell RNA - RH-30 [nTPM]":"1.3","Cell RNA - RPMI-8226 [nTPM]":"7.9","Cell RNA - RPTEC TERT1 [nTPM]":"4.4","Cell RNA - RT4 [nTPM]":"6.6","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"7.3","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"2.1","Cell RNA - SK-MEL-30 [nTPM]":"6.4","Cell RNA - SuSa [nTPM]":"7.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"16.1","Cell RNA - U-138 MG [nTPM]":"5.6","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"3.6","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"8.5","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"8.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"69.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"96.2","Single Cell Type RNA - Astrocytes [nTPM]":"52.5","Single Cell Type RNA - B-cells [nTPM]":"79.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"63.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"55.8","Single Cell Type RNA - Bipolar cells [nTPM]":"78.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"57.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"55.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"110.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"57.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"102.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.9","Single Cell Type RNA - dendritic cells [nTPM]":"101.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"48.1","Single Cell Type RNA - Early spermatids [nTPM]":"37.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"88.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"109.5","Single Cell Type RNA - Endothelial cells [nTPM]":"71.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"58.6","Single Cell Type RNA - Erythroid cells [nTPM]":"59.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"116.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"50.2","Single Cell Type RNA - Fibroblasts [nTPM]":"57.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"57.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"127.3","Single Cell Type RNA - granulocytes [nTPM]":"58.2","Single Cell Type RNA - Granulosa cells [nTPM]":"66.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.9","Single Cell Type RNA - Hepatocytes [nTPM]":"32.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.7","Single Cell Type RNA - Horizontal cells [nTPM]":"94.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"96.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.3","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"27.7","Single Cell Type RNA - Langerhans cells [nTPM]":"36.9","Single Cell Type RNA - Late spermatids [nTPM]":"21.1","Single Cell Type RNA - Leydig cells [nTPM]":"58.7","Single Cell Type RNA - Macrophages [nTPM]":"53.3","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"57.1","Single Cell Type RNA - monocytes [nTPM]":"62.3","Single Cell Type RNA - Muller glia cells [nTPM]":"41.7","Single Cell Type RNA - NK-cells [nTPM]":"76.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"57.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"86.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"52.2","Single Cell Type RNA - Paneth cells [nTPM]":"26.0","Single Cell Type RNA - Peritubular cells [nTPM]":"54.5","Single Cell Type RNA - Plasma cells [nTPM]":"72.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"57.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"125.1","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"104.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"74.0","Single Cell Type RNA - Spermatocytes [nTPM]":"85.8","Single Cell Type RNA - Spermatogonia [nTPM]":"60.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.2","Single Cell Type RNA - T-cells [nTPM]":"86.3","Single Cell Type RNA - Theca cells [nTPM]":"69.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"50.0","Single Cell Type RNA - Urothelial cells [nTPM]":"64.5"},{"Gene":"BEAN1","Gene synonym":["SCA31"],"Ensembl":"ENSG00000166546","Gene description":"Brain expressed associated with NEDD4 1","Uniprot":["Q3B7T3"],"Chromosome":"16","Position":"66427295-66493529","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"5.8","Early spermatids":"10.7","Excitatory neurons":"9.9","Extravillous trophoblasts":"10.9","Inhibitory neurons":"7.7","Late spermatids":"13.6","Oligodendrocyte precursor cells":"7.5","Spermatocytes":"6.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"9.2","BEWO":"4.2","RPTEC TERT1":"9.1","U-87 MG":"4.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053851"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA053851":"AB_2682280"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"4.1","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"9.2","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"4.2","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"9.1","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"4.1","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"10.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"13.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"BEST1","Gene synonym":["BEST","BMD","RP50","VMD2"],"Ensembl":"ENSG00000167995","Gene description":"Bestrophin 1","Uniprot":["O76090"],"Chromosome":"11","Position":"61950063-61965515","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"26.3","brain":"41.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"272.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"2.0","melanoma":"6.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"37.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"37.6"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"SK-MEL-30":"71.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057464"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057464":"AB_2683444"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"3.7","Tissue RNA - amygdala [nTPM]":"16.3","Tissue RNA - appendix [nTPM]":"8.3","Tissue RNA - basal ganglia [nTPM]":"30.5","Tissue RNA - bone marrow [nTPM]":"26.3","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"24.9","Tissue RNA - cerebral cortex [nTPM]":"23.2","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"3.8","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"4.1","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"5.9","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"5.7","Tissue RNA - hippocampal formation [nTPM]":"16.5","Tissue RNA - hypothalamus [nTPM]":"20.2","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"10.3","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"27.9","Tissue RNA - midbrain [nTPM]":"27.3","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"26.7","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"6.7","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"19.2","Tissue RNA - spleen [nTPM]":"11.0","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"5.4","Tissue RNA - thalamus [nTPM]":"28.6","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"5.3","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"41.7","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"17.7","Cell RNA - ASC TERT1 [nTPM]":"3.8","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.1","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"6.7","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"5.6","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"4.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"7.6","Cell RNA - LHCN-M2 [nTPM]":"1.9","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"71.6","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"2.3","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"10.3","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"4.6","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"37.6","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"16.3","Brain RNA - basal ganglia [nTPM]":"30.5","Brain RNA - cerebellum [nTPM]":"24.9","Brain RNA - cerebral cortex [nTPM]":"23.2","Brain RNA - hippocampal formation [nTPM]":"16.5","Brain RNA - hypothalamus [nTPM]":"20.2","Brain RNA - medulla oblongata [nTPM]":"27.9","Brain RNA - midbrain [nTPM]":"27.3","Brain RNA - pons [nTPM]":"26.7","Brain RNA - spinal cord [nTPM]":"19.2","Brain RNA - thalamus [nTPM]":"28.6","Brain RNA - white matter [nTPM]":"41.7","Single Cell Type RNA - Adipocytes [nTPM]":"2.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"59.3","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"11.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"54.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"57.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.5","Single Cell Type RNA - dendritic cells [nTPM]":"5.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.8","Single Cell Type RNA - Early spermatids [nTPM]":"8.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"16.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"29.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.4","Single Cell Type RNA - Fibroblasts [nTPM]":"32.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.0","Single Cell Type RNA - granulocytes [nTPM]":"76.4","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"13.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.7","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"75.4","Single Cell Type RNA - Langerhans cells [nTPM]":"272.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"49.0","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"14.1","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"21.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"5.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.4","Single Cell Type RNA - T-cells [nTPM]":"24.5","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.9","Single Cell Type RNA - Urothelial cells [nTPM]":"13.2"},{"Gene":"BFSP1","Gene synonym":["CP115","CP94","filensin","LIFL-H"],"Ensembl":"ENSG00000125864","Gene description":"Beaded filament structural protein 1","Uniprot":["Q12934"],"Chromosome":"20","Position":"17493905-17569220","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"5.7","NK-cells":"17.5","Spermatogonia":"11.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"2.5"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"T-cells":"2.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-RPE1":"10.8","RPTEC TERT1":"19.5","SK-BR-3":"10.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"amygdala":"2.5","cerebral cortex":"3.2","hippocampal formation":"3.6"},"Antibody":["HPA040748","HPA042038"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040748":"AB_10963786","HPA042038":"AB_10964054"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.39e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"1.5","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"2.6","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"2.0","Cell RNA - BJ hTERT+ [nTPM]":"9.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"3.7","Cell RNA - CAPAN-2 [nTPM]":"7.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"5.1","Cell RNA - HaCaT [nTPM]":"1.2","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"1.8","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"1.2","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"1.5","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"3.1","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"2.3","Cell RNA - hTERT-RPE1 [nTPM]":"10.8","Cell RNA - HUVEC TERT2 [nTPM]":"5.7","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"4.2","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"6.1","Cell RNA - OE19 [nTPM]":"5.2","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.8","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"19.5","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"2.4","Cell RNA - SK-BR-3 [nTPM]":"10.6","Cell RNA - SK-MEL-30 [nTPM]":"4.3","Cell RNA - SuSa [nTPM]":"1.2","Cell RNA - T-47d [nTPM]":"5.2","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"6.5","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"2.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"1.5","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"11.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"BFSP2","Gene synonym":["CP47","CP49","LIFL-L","phakinin"],"Ensembl":"ENSG00000170819","Gene description":"Beaded filament structural protein 2","Uniprot":["Q13515"],"Chromosome":"3","Position":"133400056-133475222","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"6.3","Melanocytes":"5.4","Plasma cells":"10.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"testis cancer":"1.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"T-reg":"13.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"43","RNA blood lineage specific nTPM":{"T-cells":"13.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Daudi":"2.4","U-698":"2.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038464","HPA062959"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038464":"AB_10672746","HPA062959":"AB_2684912"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"2.4","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"2.6","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"13.4","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"BICD2","Gene synonym":["KIAA0699"],"Ensembl":"ENSG00000185963","Gene description":"BICD cargo adaptor 2","Uniprot":["Q8TD16"],"Chromosome":"9","Position":"92711363-92764833","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"63.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"83.6","Squamous epithelial cells":"103.2","Suprabasal keratinocytes":"130.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023013","HPA024452"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":["Golgi apparatus","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023013":"AB_1845352","HPA024452":"AB_1845353"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.4","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"11.4","Tissue RNA - appendix [nTPM]":"13.5","Tissue RNA - basal ganglia [nTPM]":"10.0","Tissue RNA - bone marrow [nTPM]":"12.0","Tissue RNA - breast [nTPM]":"10.9","Tissue RNA - cerebellum [nTPM]":"10.9","Tissue RNA - cerebral cortex [nTPM]":"10.5","Tissue RNA - cervix [nTPM]":"20.8","Tissue RNA - choroid plexus [nTPM]":"7.8","Tissue RNA - colon [nTPM]":"18.5","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"15.5","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"47.0","Tissue RNA - fallopian tube [nTPM]":"12.8","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"19.8","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"8.6","Tissue RNA - kidney [nTPM]":"9.1","Tissue RNA - liver [nTPM]":"8.5","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"11.0","Tissue RNA - midbrain [nTPM]":"9.8","Tissue RNA - ovary [nTPM]":"12.5","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"17.7","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"10.4","Tissue RNA - pons [nTPM]":"10.3","Tissue RNA - prostate [nTPM]":"11.3","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"14.6","Tissue RNA - seminal vesicle [nTPM]":"13.1","Tissue RNA - skeletal muscle [nTPM]":"22.3","Tissue RNA - skin 1 [nTPM]":"63.4","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"13.7","Tissue RNA - spinal cord [nTPM]":"10.5","Tissue RNA - spleen [nTPM]":"17.3","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"9.4","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"13.8","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"15.3","Tissue RNA - tonsil [nTPM]":"16.8","Tissue RNA - urinary bladder [nTPM]":"15.2","Tissue RNA - vagina [nTPM]":"30.9","Tissue RNA - white matter [nTPM]":"12.3","Cell RNA - A-431 [nTPM]":"32.6","Cell RNA - A549 [nTPM]":"26.5","Cell RNA - AF22 [nTPM]":"19.2","Cell RNA - AN3-CA [nTPM]":"19.8","Cell RNA - ASC diff [nTPM]":"36.6","Cell RNA - ASC TERT1 [nTPM]":"25.1","Cell RNA - BEWO [nTPM]":"27.1","Cell RNA - BJ [nTPM]":"30.8","Cell RNA - BJ hTERT+ [nTPM]":"22.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.6","Cell RNA - CACO-2 [nTPM]":"15.6","Cell RNA - CAPAN-2 [nTPM]":"14.4","Cell RNA - Daudi [nTPM]":"36.3","Cell RNA - EFO-21 [nTPM]":"19.5","Cell RNA - fHDF\/TERT166 [nTPM]":"34.4","Cell RNA - GAMG [nTPM]":"22.0","Cell RNA - HaCaT [nTPM]":"99.4","Cell RNA - HAP1 [nTPM]":"21.8","Cell RNA - HBEC3-KT [nTPM]":"49.1","Cell RNA - HBF TERT88 [nTPM]":"19.4","Cell RNA - HDLM-2 [nTPM]":"17.4","Cell RNA - HEK 293 [nTPM]":"23.5","Cell RNA - HEL [nTPM]":"19.2","Cell RNA - HeLa [nTPM]":"25.6","Cell RNA - Hep G2 [nTPM]":"21.7","Cell RNA - HHSteC [nTPM]":"21.8","Cell RNA - HL-60 [nTPM]":"26.9","Cell RNA - HMC-1 [nTPM]":"30.0","Cell RNA - HSkMC [nTPM]":"25.8","Cell RNA - hTCEpi [nTPM]":"67.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.8","Cell RNA - hTERT-HME1 [nTPM]":"22.0","Cell RNA - hTERT-RPE1 [nTPM]":"20.4","Cell RNA - HUVEC TERT2 [nTPM]":"26.0","Cell RNA - JURKAT [nTPM]":"15.4","Cell RNA - K-562 [nTPM]":"19.3","Cell RNA - Karpas-707 [nTPM]":"27.5","Cell RNA - LHCN-M2 [nTPM]":"38.1","Cell RNA - MCF7 [nTPM]":"21.4","Cell RNA - MOLT-4 [nTPM]":"25.6","Cell RNA - NB-4 [nTPM]":"16.7","Cell RNA - NTERA-2 [nTPM]":"13.3","Cell RNA - OE19 [nTPM]":"23.8","Cell RNA - PC-3 [nTPM]":"32.0","Cell RNA - REH [nTPM]":"27.8","Cell RNA - RH-30 [nTPM]":"41.8","Cell RNA - RPMI-8226 [nTPM]":"19.3","Cell RNA - RPTEC TERT1 [nTPM]":"27.8","Cell RNA - RT4 [nTPM]":"27.0","Cell RNA - SCLC-21H [nTPM]":"13.4","Cell RNA - SH-SY5Y [nTPM]":"20.7","Cell RNA - SiHa [nTPM]":"21.7","Cell RNA - SK-BR-3 [nTPM]":"19.9","Cell RNA - SK-MEL-30 [nTPM]":"14.3","Cell RNA - SuSa [nTPM]":"19.2","Cell RNA - T-47d [nTPM]":"8.2","Cell RNA - THP-1 [nTPM]":"12.3","Cell RNA - TIME [nTPM]":"34.9","Cell RNA - U-138 MG [nTPM]":"31.8","Cell RNA - U-2 OS [nTPM]":"21.1","Cell RNA - U-2197 [nTPM]":"53.9","Cell RNA - U-251 MG [nTPM]":"33.9","Cell RNA - U-266\/70 [nTPM]":"22.5","Cell RNA - U-266\/84 [nTPM]":"17.5","Cell RNA - U-698 [nTPM]":"31.9","Cell RNA - U-87 MG [nTPM]":"26.9","Cell RNA - U-937 [nTPM]":"16.3","Cell RNA - WM-115 [nTPM]":"28.4","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"3.4","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"3.6","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"3.8","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"7.5","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"5.9","Blood RNA - plasmacytoid DC [nTPM]":"3.2","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"11.4","Brain RNA - basal ganglia [nTPM]":"10.0","Brain RNA - cerebellum [nTPM]":"10.9","Brain RNA - cerebral cortex [nTPM]":"10.5","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"8.6","Brain RNA - medulla oblongata [nTPM]":"11.0","Brain RNA - midbrain [nTPM]":"9.8","Brain RNA - pons [nTPM]":"10.3","Brain RNA - spinal cord [nTPM]":"10.5","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"12.3","Single Cell Type RNA - Adipocytes [nTPM]":"21.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"27.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"73.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"83.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"54.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"16.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - dendritic cells [nTPM]":"26.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.7","Single Cell Type RNA - Endothelial cells [nTPM]":"26.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.5","Single Cell Type RNA - Fibroblasts [nTPM]":"26.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.1","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"13.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.2","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"32.4","Single Cell Type RNA - Langerhans cells [nTPM]":"30.2","Single Cell Type RNA - Late spermatids [nTPM]":"7.6","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"40.7","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"38.9","Single Cell Type RNA - Muller glia cells [nTPM]":"22.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.5","Single Cell Type RNA - Paneth cells [nTPM]":"3.6","Single Cell Type RNA - Peritubular cells [nTPM]":"33.4","Single Cell Type RNA - Plasma cells [nTPM]":"22.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.1","Single Cell Type RNA - Spermatocytes [nTPM]":"9.7","Single Cell Type RNA - Spermatogonia [nTPM]":"8.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"103.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"130.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"17.2","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.6","Single Cell Type RNA - Urothelial cells [nTPM]":"20.3"},{"Gene":"BRAT1","Gene synonym":["BAAT1","C7orf27","MGC22916"],"Ensembl":"ENSG00000106009","Gene description":"BRCA1 associated ATM activator 1","Uniprot":["Q6PJG6"],"Chromosome":"7","Position":"2537810-2555694","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029455","HPA076508"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA029455":"AB_10600761","HPA076508":"AB_2686803"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.90e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.4","Tissue RNA - adrenal gland [nTPM]":"31.0","Tissue RNA - amygdala [nTPM]":"10.7","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"7.9","Tissue RNA - breast [nTPM]":"17.8","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"14.3","Tissue RNA - cervix [nTPM]":"22.5","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"16.2","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"19.4","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"15.1","Tissue RNA - fallopian tube [nTPM]":"19.2","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"14.5","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"11.2","Tissue RNA - kidney [nTPM]":"15.2","Tissue RNA - liver [nTPM]":"20.7","Tissue RNA - lung [nTPM]":"12.2","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"13.5","Tissue RNA - midbrain [nTPM]":"11.4","Tissue RNA - ovary [nTPM]":"21.6","Tissue RNA - pancreas [nTPM]":"20.2","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"19.8","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"24.5","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"17.4","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"14.8","Tissue RNA - skin 1 [nTPM]":"21.6","Tissue RNA - small intestine [nTPM]":"16.6","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"10.6","Tissue RNA - spleen [nTPM]":"21.1","Tissue RNA - stomach 1 [nTPM]":"19.6","Tissue RNA - testis [nTPM]":"31.5","Tissue RNA - thalamus [nTPM]":"11.2","Tissue RNA - thymus [nTPM]":"5.0","Tissue RNA - thyroid gland [nTPM]":"18.7","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"17.6","Tissue RNA - vagina [nTPM]":"18.8","Tissue RNA - white matter [nTPM]":"10.5","Cell RNA - A-431 [nTPM]":"35.1","Cell RNA - A549 [nTPM]":"31.1","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"27.2","Cell RNA - ASC diff [nTPM]":"6.8","Cell RNA - ASC TERT1 [nTPM]":"6.3","Cell RNA - BEWO [nTPM]":"24.5","Cell RNA - BJ [nTPM]":"11.7","Cell RNA - BJ hTERT+ [nTPM]":"6.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.5","Cell RNA - CACO-2 [nTPM]":"22.5","Cell RNA - CAPAN-2 [nTPM]":"21.5","Cell RNA - Daudi [nTPM]":"26.3","Cell RNA - EFO-21 [nTPM]":"18.1","Cell RNA - fHDF\/TERT166 [nTPM]":"7.8","Cell RNA - GAMG [nTPM]":"19.4","Cell RNA - HaCaT [nTPM]":"35.1","Cell RNA - HAP1 [nTPM]":"8.8","Cell RNA - HBEC3-KT [nTPM]":"13.7","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"10.4","Cell RNA - HEK 293 [nTPM]":"44.4","Cell RNA - HEL [nTPM]":"12.2","Cell RNA - HeLa [nTPM]":"23.5","Cell RNA - Hep G2 [nTPM]":"14.3","Cell RNA - HHSteC [nTPM]":"8.7","Cell RNA - HL-60 [nTPM]":"16.5","Cell RNA - HMC-1 [nTPM]":"18.2","Cell RNA - HSkMC [nTPM]":"10.6","Cell RNA - hTCEpi [nTPM]":"9.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.2","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"11.4","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"39.1","Cell RNA - Karpas-707 [nTPM]":"9.6","Cell RNA - LHCN-M2 [nTPM]":"7.1","Cell RNA - MCF7 [nTPM]":"50.0","Cell RNA - MOLT-4 [nTPM]":"11.8","Cell RNA - NB-4 [nTPM]":"77.9","Cell RNA - NTERA-2 [nTPM]":"35.3","Cell RNA - OE19 [nTPM]":"8.8","Cell RNA - PC-3 [nTPM]":"47.0","Cell RNA - REH [nTPM]":"28.6","Cell RNA - RH-30 [nTPM]":"21.9","Cell RNA - RPMI-8226 [nTPM]":"25.5","Cell RNA - RPTEC TERT1 [nTPM]":"6.5","Cell RNA - RT4 [nTPM]":"11.3","Cell RNA - SCLC-21H [nTPM]":"19.5","Cell RNA - SH-SY5Y [nTPM]":"30.2","Cell RNA - SiHa [nTPM]":"17.1","Cell RNA - SK-BR-3 [nTPM]":"29.8","Cell RNA - SK-MEL-30 [nTPM]":"12.9","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"26.5","Cell RNA - THP-1 [nTPM]":"33.4","Cell RNA - TIME [nTPM]":"11.8","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"43.3","Cell RNA - U-2197 [nTPM]":"28.5","Cell RNA - U-251 MG [nTPM]":"23.2","Cell RNA - U-266\/70 [nTPM]":"20.7","Cell RNA - U-266\/84 [nTPM]":"17.3","Cell RNA - U-698 [nTPM]":"19.0","Cell RNA - U-87 MG [nTPM]":"15.2","Cell RNA - U-937 [nTPM]":"32.8","Cell RNA - WM-115 [nTPM]":"33.2","Blood RNA - basophil [nTPM]":"5.1","Blood RNA - classical monocyte [nTPM]":"30.8","Blood RNA - eosinophil [nTPM]":"17.5","Blood RNA - gdT-cell [nTPM]":"21.9","Blood RNA - intermediate monocyte [nTPM]":"28.2","Blood RNA - MAIT T-cell [nTPM]":"19.3","Blood RNA - memory B-cell [nTPM]":"18.6","Blood RNA - memory CD4 T-cell [nTPM]":"19.8","Blood RNA - memory CD8 T-cell [nTPM]":"22.6","Blood RNA - myeloid DC [nTPM]":"32.4","Blood RNA - naive B-cell [nTPM]":"15.2","Blood RNA - naive CD4 T-cell [nTPM]":"16.3","Blood RNA - naive CD8 T-cell [nTPM]":"17.9","Blood RNA - neutrophil [nTPM]":"25.4","Blood RNA - NK-cell [nTPM]":"15.9","Blood RNA - non-classical monocyte [nTPM]":"27.1","Blood RNA - plasmacytoid DC [nTPM]":"22.7","Blood RNA - T-reg [nTPM]":"18.4","Blood RNA - total PBMC [nTPM]":"22.8","Brain RNA - amygdala [nTPM]":"10.7","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"14.3","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"11.2","Brain RNA - medulla oblongata [nTPM]":"13.5","Brain RNA - midbrain [nTPM]":"11.4","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"10.6","Brain RNA - thalamus [nTPM]":"11.2","Brain RNA - white matter [nTPM]":"10.5","Single Cell Type RNA - Adipocytes [nTPM]":"10.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"11.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"12.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"14.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - dendritic cells [nTPM]":"15.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"10.6","Single Cell Type RNA - Early spermatids [nTPM]":"20.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.9","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.5","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"34.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"15.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.1","Single Cell Type RNA - Langerhans cells [nTPM]":"6.7","Single Cell Type RNA - Late spermatids [nTPM]":"9.4","Single Cell Type RNA - Leydig cells [nTPM]":"22.7","Single Cell Type RNA - Macrophages [nTPM]":"13.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"17.6","Single Cell Type RNA - Muller glia cells [nTPM]":"14.4","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.0","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"14.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.7","Single Cell Type RNA - Spermatocytes [nTPM]":"28.8","Single Cell Type RNA - Spermatogonia [nTPM]":"39.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - T-cells [nTPM]":"11.9","Single Cell Type RNA - Theca cells [nTPM]":"31.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.9","Single Cell Type RNA - Urothelial cells [nTPM]":"7.6"},{"Gene":"BSCL2","Gene synonym":["GNG3LG","seipin","SPG17"],"Ensembl":"ENSG00000168000","Gene description":"BSCL2 lipid droplet biogenesis associated, seipin","Uniprot":["Q96G97"],"Chromosome":"11","Position":"62690275-62709845","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":null,"Disease involvement":["Congenital generalized lipodystrophy","Diabetes mellitus","Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"292.1","pituitary gland":"237.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"35.9","Late spermatids":"53.1","Plasma cells":"86.3","Spermatocytes":"32.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"242.1","RPMI-8226":"176.1","SCLC-21H":"181.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042394"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042394":"AB_10794047"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.9","Tissue RNA - adrenal gland [nTPM]":"88.1","Tissue RNA - amygdala [nTPM]":"126.6","Tissue RNA - appendix [nTPM]":"7.4","Tissue RNA - basal ganglia [nTPM]":"133.2","Tissue RNA - bone marrow [nTPM]":"12.0","Tissue RNA - breast [nTPM]":"26.2","Tissue RNA - cerebellum [nTPM]":"75.0","Tissue RNA - cerebral cortex [nTPM]":"155.6","Tissue RNA - cervix [nTPM]":"38.2","Tissue RNA - choroid plexus [nTPM]":"85.4","Tissue RNA - colon [nTPM]":"24.3","Tissue RNA - duodenum [nTPM]":"10.8","Tissue RNA - endometrium 1 [nTPM]":"28.4","Tissue RNA - epididymis [nTPM]":"156.7","Tissue RNA - esophagus [nTPM]":"24.1","Tissue RNA - fallopian tube [nTPM]":"63.7","Tissue RNA - gallbladder [nTPM]":"21.5","Tissue RNA - heart muscle [nTPM]":"18.7","Tissue RNA - hippocampal formation [nTPM]":"134.9","Tissue RNA - hypothalamus [nTPM]":"292.1","Tissue RNA - kidney [nTPM]":"50.8","Tissue RNA - liver [nTPM]":"39.3","Tissue RNA - lung [nTPM]":"26.7","Tissue RNA - lymph node [nTPM]":"15.3","Tissue RNA - medulla oblongata [nTPM]":"138.1","Tissue RNA - midbrain [nTPM]":"139.0","Tissue RNA - ovary [nTPM]":"32.7","Tissue RNA - pancreas [nTPM]":"79.4","Tissue RNA - parathyroid gland [nTPM]":"61.7","Tissue RNA - pituitary gland [nTPM]":"237.0","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"203.4","Tissue RNA - prostate [nTPM]":"35.4","Tissue RNA - rectum [nTPM]":"13.3","Tissue RNA - retina [nTPM]":"52.6","Tissue RNA - salivary gland [nTPM]":"66.1","Tissue RNA - seminal vesicle [nTPM]":"30.3","Tissue RNA - skeletal muscle [nTPM]":"30.9","Tissue RNA - skin 1 [nTPM]":"25.1","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"13.7","Tissue RNA - spinal cord [nTPM]":"83.1","Tissue RNA - spleen [nTPM]":"16.2","Tissue RNA - stomach 1 [nTPM]":"37.1","Tissue RNA - testis [nTPM]":"190.3","Tissue RNA - thalamus [nTPM]":"169.3","Tissue RNA - thymus [nTPM]":"14.4","Tissue RNA - thyroid gland [nTPM]":"37.9","Tissue RNA - tongue [nTPM]":"15.5","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"17.5","Tissue RNA - vagina [nTPM]":"26.1","Tissue RNA - white matter [nTPM]":"89.9","Cell RNA - A-431 [nTPM]":"18.0","Cell RNA - A549 [nTPM]":"61.7","Cell RNA - AF22 [nTPM]":"49.6","Cell RNA - AN3-CA [nTPM]":"83.8","Cell RNA - ASC diff [nTPM]":"130.8","Cell RNA - ASC TERT1 [nTPM]":"41.5","Cell RNA - BEWO [nTPM]":"7.2","Cell RNA - BJ [nTPM]":"7.2","Cell RNA - BJ hTERT+ [nTPM]":"34.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.5","Cell RNA - CACO-2 [nTPM]":"9.6","Cell RNA - CAPAN-2 [nTPM]":"26.3","Cell RNA - Daudi [nTPM]":"11.9","Cell RNA - EFO-21 [nTPM]":"16.5","Cell RNA - fHDF\/TERT166 [nTPM]":"25.2","Cell RNA - GAMG [nTPM]":"11.8","Cell RNA - HaCaT [nTPM]":"62.1","Cell RNA - HAP1 [nTPM]":"5.2","Cell RNA - HBEC3-KT [nTPM]":"21.8","Cell RNA - HBF TERT88 [nTPM]":"7.0","Cell RNA - HDLM-2 [nTPM]":"30.7","Cell RNA - HEK 293 [nTPM]":"5.0","Cell RNA - HEL [nTPM]":"10.9","Cell RNA - HeLa [nTPM]":"33.4","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"27.7","Cell RNA - HL-60 [nTPM]":"9.7","Cell RNA - HMC-1 [nTPM]":"13.5","Cell RNA - HSkMC [nTPM]":"27.8","Cell RNA - hTCEpi [nTPM]":"16.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.9","Cell RNA - hTERT-HME1 [nTPM]":"10.9","Cell RNA - hTERT-RPE1 [nTPM]":"19.7","Cell RNA - HUVEC TERT2 [nTPM]":"10.8","Cell RNA - JURKAT [nTPM]":"33.0","Cell RNA - K-562 [nTPM]":"7.8","Cell RNA - Karpas-707 [nTPM]":"242.1","Cell RNA - LHCN-M2 [nTPM]":"19.8","Cell RNA - MCF7 [nTPM]":"44.0","Cell RNA - MOLT-4 [nTPM]":"11.4","Cell RNA - NB-4 [nTPM]":"21.8","Cell RNA - NTERA-2 [nTPM]":"132.4","Cell RNA - OE19 [nTPM]":"13.9","Cell RNA - PC-3 [nTPM]":"13.0","Cell RNA - REH [nTPM]":"21.3","Cell RNA - RH-30 [nTPM]":"4.2","Cell RNA - RPMI-8226 [nTPM]":"176.1","Cell RNA - RPTEC TERT1 [nTPM]":"65.0","Cell RNA - RT4 [nTPM]":"2.4","Cell RNA - SCLC-21H [nTPM]":"181.2","Cell RNA - SH-SY5Y [nTPM]":"29.4","Cell RNA - SiHa [nTPM]":"28.2","Cell RNA - SK-BR-3 [nTPM]":"13.9","Cell RNA - SK-MEL-30 [nTPM]":"25.3","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"41.3","Cell RNA - THP-1 [nTPM]":"15.3","Cell RNA - TIME [nTPM]":"6.5","Cell RNA - U-138 MG [nTPM]":"16.5","Cell RNA - U-2 OS [nTPM]":"3.7","Cell RNA - U-2197 [nTPM]":"24.5","Cell RNA - U-251 MG [nTPM]":"4.2","Cell RNA - U-266\/70 [nTPM]":"32.2","Cell RNA - U-266\/84 [nTPM]":"72.5","Cell RNA - U-698 [nTPM]":"16.6","Cell RNA - U-87 MG [nTPM]":"82.4","Cell RNA - U-937 [nTPM]":"3.2","Cell RNA - WM-115 [nTPM]":"14.5","Blood RNA - basophil [nTPM]":"26.6","Blood RNA - classical monocyte [nTPM]":"59.2","Blood RNA - eosinophil [nTPM]":"34.6","Blood RNA - gdT-cell [nTPM]":"24.7","Blood RNA - intermediate monocyte [nTPM]":"46.2","Blood RNA - MAIT T-cell [nTPM]":"27.4","Blood RNA - memory B-cell [nTPM]":"27.5","Blood RNA - memory CD4 T-cell [nTPM]":"25.5","Blood RNA - memory CD8 T-cell [nTPM]":"26.1","Blood RNA - myeloid DC [nTPM]":"42.4","Blood RNA - naive B-cell [nTPM]":"29.7","Blood RNA - naive CD4 T-cell [nTPM]":"25.7","Blood RNA - naive CD8 T-cell [nTPM]":"27.0","Blood RNA - neutrophil [nTPM]":"14.2","Blood RNA - NK-cell [nTPM]":"41.0","Blood RNA - non-classical monocyte [nTPM]":"40.3","Blood RNA - plasmacytoid DC [nTPM]":"54.3","Blood RNA - T-reg [nTPM]":"33.1","Blood RNA - total PBMC [nTPM]":"43.3","Brain RNA - amygdala [nTPM]":"126.6","Brain RNA - basal ganglia [nTPM]":"133.2","Brain RNA - cerebellum [nTPM]":"75.0","Brain RNA - cerebral cortex [nTPM]":"155.6","Brain RNA - hippocampal formation [nTPM]":"134.9","Brain RNA - hypothalamus [nTPM]":"292.1","Brain RNA - medulla oblongata [nTPM]":"138.1","Brain RNA - midbrain [nTPM]":"139.0","Brain RNA - pons [nTPM]":"203.4","Brain RNA - spinal cord [nTPM]":"83.1","Brain RNA - thalamus [nTPM]":"169.3","Brain RNA - white matter [nTPM]":"89.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.9","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"25.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"9.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"53.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"6.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"86.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.1","Single Cell Type RNA - Spermatocytes [nTPM]":"32.6","Single Cell Type RNA - Spermatogonia [nTPM]":"18.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"C12orf65","Gene synonym":["FLJ38663","SPG55"],"Ensembl":"ENSG00000130921","Gene description":"Chromosome 12 open reading frame 65","Uniprot":["Q9H3J6"],"Chromosome":"12","Position":"123233385-123258079","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["RNA-binding"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"60.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057595"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA057595":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.29e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.82e-5"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"12.6","Tissue RNA - amygdala [nTPM]":"16.2","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"16.1","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"8.0","Tissue RNA - cerebellum [nTPM]":"23.0","Tissue RNA - cerebral cortex [nTPM]":"19.6","Tissue RNA - cervix [nTPM]":"13.0","Tissue RNA - choroid plexus [nTPM]":"13.5","Tissue RNA - colon [nTPM]":"10.9","Tissue RNA - duodenum [nTPM]":"11.4","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"13.8","Tissue RNA - esophagus [nTPM]":"9.5","Tissue RNA - fallopian tube [nTPM]":"11.4","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"15.0","Tissue RNA - hippocampal formation [nTPM]":"16.0","Tissue RNA - hypothalamus [nTPM]":"13.2","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"8.9","Tissue RNA - lymph node [nTPM]":"18.2","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"12.3","Tissue RNA - ovary [nTPM]":"17.2","Tissue RNA - pancreas [nTPM]":"8.5","Tissue RNA - parathyroid gland [nTPM]":"10.2","Tissue RNA - pituitary gland [nTPM]":"19.7","Tissue RNA - placenta [nTPM]":"7.3","Tissue RNA - pons [nTPM]":"14.9","Tissue RNA - prostate [nTPM]":"13.7","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"15.7","Tissue RNA - salivary gland [nTPM]":"16.2","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"13.0","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"11.3","Tissue RNA - smooth muscle [nTPM]":"7.0","Tissue RNA - spinal cord [nTPM]":"8.8","Tissue RNA - spleen [nTPM]":"12.8","Tissue RNA - stomach 1 [nTPM]":"10.6","Tissue RNA - testis [nTPM]":"16.7","Tissue RNA - thalamus [nTPM]":"14.8","Tissue RNA - thymus [nTPM]":"60.0","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"12.5","Tissue RNA - tonsil [nTPM]":"13.4","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"11.0","Tissue RNA - white matter [nTPM]":"18.3","Cell RNA - A-431 [nTPM]":"28.4","Cell RNA - A549 [nTPM]":"20.5","Cell RNA - AF22 [nTPM]":"20.8","Cell RNA - AN3-CA [nTPM]":"39.1","Cell RNA - ASC diff [nTPM]":"12.0","Cell RNA - ASC TERT1 [nTPM]":"11.1","Cell RNA - BEWO [nTPM]":"13.7","Cell RNA - BJ [nTPM]":"22.3","Cell RNA - BJ hTERT+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.0","Cell RNA - CACO-2 [nTPM]":"21.8","Cell RNA - CAPAN-2 [nTPM]":"15.8","Cell RNA - Daudi [nTPM]":"36.1","Cell RNA - EFO-21 [nTPM]":"20.3","Cell RNA - fHDF\/TERT166 [nTPM]":"8.4","Cell RNA - GAMG [nTPM]":"23.5","Cell RNA - HaCaT [nTPM]":"20.4","Cell RNA - HAP1 [nTPM]":"25.7","Cell RNA - HBEC3-KT [nTPM]":"12.5","Cell RNA - HBF TERT88 [nTPM]":"25.0","Cell RNA - HDLM-2 [nTPM]":"29.2","Cell RNA - HEK 293 [nTPM]":"22.5","Cell RNA - HEL [nTPM]":"44.0","Cell RNA - HeLa [nTPM]":"20.7","Cell RNA - Hep G2 [nTPM]":"18.6","Cell RNA - HHSteC [nTPM]":"26.1","Cell RNA - HL-60 [nTPM]":"20.4","Cell RNA - HMC-1 [nTPM]":"19.7","Cell RNA - HSkMC [nTPM]":"14.2","Cell RNA - hTCEpi [nTPM]":"33.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.9","Cell RNA - hTERT-HME1 [nTPM]":"35.1","Cell RNA - hTERT-RPE1 [nTPM]":"37.0","Cell RNA - HUVEC TERT2 [nTPM]":"17.0","Cell RNA - JURKAT [nTPM]":"53.6","Cell RNA - K-562 [nTPM]":"45.6","Cell RNA - Karpas-707 [nTPM]":"13.4","Cell RNA - LHCN-M2 [nTPM]":"16.7","Cell RNA - MCF7 [nTPM]":"12.3","Cell RNA - MOLT-4 [nTPM]":"46.2","Cell RNA - NB-4 [nTPM]":"39.3","Cell RNA - NTERA-2 [nTPM]":"13.7","Cell RNA - OE19 [nTPM]":"25.6","Cell RNA - PC-3 [nTPM]":"31.7","Cell RNA - REH [nTPM]":"35.7","Cell RNA - RH-30 [nTPM]":"25.9","Cell RNA - RPMI-8226 [nTPM]":"33.5","Cell RNA - RPTEC TERT1 [nTPM]":"22.8","Cell RNA - RT4 [nTPM]":"13.0","Cell RNA - SCLC-21H [nTPM]":"40.7","Cell RNA - SH-SY5Y [nTPM]":"18.2","Cell RNA - SiHa [nTPM]":"24.0","Cell RNA - SK-BR-3 [nTPM]":"8.8","Cell RNA - SK-MEL-30 [nTPM]":"23.4","Cell RNA - SuSa [nTPM]":"16.5","Cell RNA - T-47d [nTPM]":"18.3","Cell RNA - THP-1 [nTPM]":"24.7","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"23.1","Cell RNA - U-2 OS [nTPM]":"27.3","Cell RNA - U-2197 [nTPM]":"23.3","Cell RNA - U-251 MG [nTPM]":"24.4","Cell RNA - U-266\/70 [nTPM]":"22.7","Cell RNA - U-266\/84 [nTPM]":"28.3","Cell RNA - U-698 [nTPM]":"32.6","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"26.2","Cell RNA - WM-115 [nTPM]":"28.1","Blood RNA - basophil [nTPM]":"85.3","Blood RNA - classical monocyte [nTPM]":"12.9","Blood RNA - eosinophil [nTPM]":"50.6","Blood RNA - gdT-cell [nTPM]":"53.9","Blood RNA - intermediate monocyte [nTPM]":"14.9","Blood RNA - MAIT T-cell [nTPM]":"67.6","Blood RNA - memory B-cell [nTPM]":"83.9","Blood RNA - memory CD4 T-cell [nTPM]":"72.3","Blood RNA - memory CD8 T-cell [nTPM]":"71.9","Blood RNA - myeloid DC [nTPM]":"21.7","Blood RNA - naive B-cell [nTPM]":"73.5","Blood RNA - naive CD4 T-cell [nTPM]":"96.6","Blood RNA - naive CD8 T-cell [nTPM]":"78.2","Blood RNA - neutrophil [nTPM]":"11.8","Blood RNA - NK-cell [nTPM]":"63.3","Blood RNA - non-classical monocyte [nTPM]":"16.3","Blood RNA - plasmacytoid DC [nTPM]":"36.6","Blood RNA - T-reg [nTPM]":"73.1","Blood RNA - total PBMC [nTPM]":"33.5","Brain RNA - amygdala [nTPM]":"16.2","Brain RNA - basal ganglia [nTPM]":"16.1","Brain RNA - cerebellum [nTPM]":"23.0","Brain RNA - cerebral cortex [nTPM]":"19.6","Brain RNA - hippocampal formation [nTPM]":"16.0","Brain RNA - hypothalamus [nTPM]":"13.2","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"12.3","Brain RNA - pons [nTPM]":"14.9","Brain RNA - spinal cord [nTPM]":"8.8","Brain RNA - thalamus [nTPM]":"14.8","Brain RNA - white matter [nTPM]":"18.3","Single Cell Type RNA - Adipocytes [nTPM]":"46.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.7","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"54.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"45.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"59.2","Single Cell Type RNA - Bipolar cells [nTPM]":"34.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"52.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"18.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.1","Single Cell Type RNA - dendritic cells [nTPM]":"56.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"20.7","Single Cell Type RNA - Early spermatids [nTPM]":"22.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.2","Single Cell Type RNA - Endothelial cells [nTPM]":"27.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"37.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.8","Single Cell Type RNA - Fibroblasts [nTPM]":"41.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.2","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"24.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.5","Single Cell Type RNA - Hepatocytes [nTPM]":"33.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.3","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.7","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"9.2","Single Cell Type RNA - Langerhans cells [nTPM]":"24.2","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"37.9","Single Cell Type RNA - Macrophages [nTPM]":"19.7","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"26.3","Single Cell Type RNA - Muller glia cells [nTPM]":"35.7","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.6","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"42.2","Single Cell Type RNA - Plasma cells [nTPM]":"42.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.1","Single Cell Type RNA - Spermatocytes [nTPM]":"115.2","Single Cell Type RNA - Spermatogonia [nTPM]":"59.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.8","Single Cell Type RNA - T-cells [nTPM]":"63.0","Single Cell Type RNA - Theca cells [nTPM]":"43.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.8","Single Cell Type RNA - Urothelial cells [nTPM]":"8.0"},{"Gene":"C19orf12","Gene synonym":["DKFZP762D096","MGC10922","MPAN","NBIA4","SPG43"],"Ensembl":"ENSG00000131943","Gene description":"Chromosome 19 open reading frame 12","Uniprot":["Q9NSK7"],"Chromosome":"19","Position":"29698886-29715789","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"118.9","tongue":"105.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"62.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046930"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046930":"AB_10962836"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Tissue RNA - adipose tissue [nTPM]":"118.9","Tissue RNA - adrenal gland [nTPM]":"25.3","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"14.4","Tissue RNA - basal ganglia [nTPM]":"25.8","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"40.8","Tissue RNA - cerebellum [nTPM]":"16.6","Tissue RNA - cerebral cortex [nTPM]":"24.8","Tissue RNA - cervix [nTPM]":"13.8","Tissue RNA - choroid plexus [nTPM]":"12.6","Tissue RNA - colon [nTPM]":"16.8","Tissue RNA - duodenum [nTPM]":"19.5","Tissue RNA - endometrium 1 [nTPM]":"14.3","Tissue RNA - epididymis [nTPM]":"9.0","Tissue RNA - esophagus [nTPM]":"13.2","Tissue RNA - fallopian tube [nTPM]":"12.8","Tissue RNA - gallbladder [nTPM]":"12.9","Tissue RNA - heart muscle [nTPM]":"30.9","Tissue RNA - hippocampal formation [nTPM]":"23.9","Tissue RNA - hypothalamus [nTPM]":"22.7","Tissue RNA - kidney [nTPM]":"20.8","Tissue RNA - liver [nTPM]":"69.3","Tissue RNA - lung [nTPM]":"11.3","Tissue RNA - lymph node [nTPM]":"21.2","Tissue RNA - medulla oblongata [nTPM]":"20.5","Tissue RNA - midbrain [nTPM]":"20.3","Tissue RNA - ovary [nTPM]":"14.7","Tissue RNA - pancreas [nTPM]":"17.1","Tissue RNA - parathyroid gland [nTPM]":"15.4","Tissue RNA - pituitary gland [nTPM]":"14.5","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"21.7","Tissue RNA - prostate [nTPM]":"14.1","Tissue RNA - rectum [nTPM]":"9.3","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"18.1","Tissue RNA - seminal vesicle [nTPM]":"12.4","Tissue RNA - skeletal muscle [nTPM]":"62.2","Tissue RNA - skin 1 [nTPM]":"14.7","Tissue RNA - small intestine [nTPM]":"17.6","Tissue RNA - smooth muscle [nTPM]":"13.4","Tissue RNA - spinal cord [nTPM]":"16.8","Tissue RNA - spleen [nTPM]":"16.0","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"7.3","Tissue RNA - thalamus [nTPM]":"23.1","Tissue RNA - thymus [nTPM]":"14.1","Tissue RNA - thyroid gland [nTPM]":"10.7","Tissue RNA - tongue [nTPM]":"105.5","Tissue RNA - tonsil [nTPM]":"13.6","Tissue RNA - urinary bladder [nTPM]":"15.2","Tissue RNA - vagina [nTPM]":"11.7","Tissue RNA - white matter [nTPM]":"19.9","Cell RNA - A-431 [nTPM]":"19.9","Cell RNA - A549 [nTPM]":"39.4","Cell RNA - AF22 [nTPM]":"18.4","Cell RNA - AN3-CA [nTPM]":"23.2","Cell RNA - ASC diff [nTPM]":"45.0","Cell RNA - ASC TERT1 [nTPM]":"27.5","Cell RNA - BEWO [nTPM]":"28.8","Cell RNA - BJ [nTPM]":"23.1","Cell RNA - BJ hTERT+ [nTPM]":"22.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.2","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"8.1","Cell RNA - Daudi [nTPM]":"16.1","Cell RNA - EFO-21 [nTPM]":"24.1","Cell RNA - fHDF\/TERT166 [nTPM]":"29.1","Cell RNA - GAMG [nTPM]":"20.4","Cell RNA - HaCaT [nTPM]":"8.5","Cell RNA - HAP1 [nTPM]":"15.7","Cell RNA - HBEC3-KT [nTPM]":"9.5","Cell RNA - HBF TERT88 [nTPM]":"15.1","Cell RNA - HDLM-2 [nTPM]":"42.8","Cell RNA - HEK 293 [nTPM]":"28.3","Cell RNA - HEL [nTPM]":"18.0","Cell RNA - HeLa [nTPM]":"13.5","Cell RNA - Hep G2 [nTPM]":"33.2","Cell RNA - HHSteC [nTPM]":"25.1","Cell RNA - HL-60 [nTPM]":"14.0","Cell RNA - HMC-1 [nTPM]":"22.8","Cell RNA - HSkMC [nTPM]":"31.8","Cell RNA - hTCEpi [nTPM]":"20.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.7","Cell RNA - hTERT-HME1 [nTPM]":"10.9","Cell RNA - hTERT-RPE1 [nTPM]":"18.0","Cell RNA - HUVEC TERT2 [nTPM]":"20.1","Cell RNA - JURKAT [nTPM]":"9.8","Cell RNA - K-562 [nTPM]":"14.0","Cell RNA - Karpas-707 [nTPM]":"20.3","Cell RNA - LHCN-M2 [nTPM]":"23.7","Cell RNA - MCF7 [nTPM]":"13.8","Cell RNA - MOLT-4 [nTPM]":"9.9","Cell RNA - NB-4 [nTPM]":"10.1","Cell RNA - NTERA-2 [nTPM]":"11.1","Cell RNA - OE19 [nTPM]":"17.3","Cell RNA - PC-3 [nTPM]":"9.9","Cell RNA - REH [nTPM]":"19.2","Cell RNA - RH-30 [nTPM]":"19.1","Cell RNA - RPMI-8226 [nTPM]":"12.3","Cell RNA - RPTEC TERT1 [nTPM]":"17.2","Cell RNA - RT4 [nTPM]":"20.1","Cell RNA - SCLC-21H [nTPM]":"11.3","Cell RNA - SH-SY5Y [nTPM]":"23.8","Cell RNA - SiHa [nTPM]":"13.9","Cell RNA - SK-BR-3 [nTPM]":"17.8","Cell RNA - SK-MEL-30 [nTPM]":"37.0","Cell RNA - SuSa [nTPM]":"18.8","Cell RNA - T-47d [nTPM]":"7.6","Cell RNA - THP-1 [nTPM]":"15.4","Cell RNA - TIME [nTPM]":"20.9","Cell RNA - U-138 MG [nTPM]":"47.4","Cell RNA - U-2 OS [nTPM]":"37.0","Cell RNA - U-2197 [nTPM]":"19.5","Cell RNA - U-251 MG [nTPM]":"21.2","Cell RNA - U-266\/70 [nTPM]":"28.4","Cell RNA - U-266\/84 [nTPM]":"27.1","Cell RNA - U-698 [nTPM]":"12.0","Cell RNA - U-87 MG [nTPM]":"28.3","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"20.3","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"16.0","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"9.4","Blood RNA - memory B-cell [nTPM]":"4.6","Blood RNA - memory CD4 T-cell [nTPM]":"9.1","Blood RNA - memory CD8 T-cell [nTPM]":"11.6","Blood RNA - myeloid DC [nTPM]":"2.2","Blood RNA - naive B-cell [nTPM]":"3.6","Blood RNA - naive CD4 T-cell [nTPM]":"9.2","Blood RNA - naive CD8 T-cell [nTPM]":"11.5","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"7.1","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"11.9","Blood RNA - total PBMC [nTPM]":"8.0","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"25.8","Brain RNA - cerebellum [nTPM]":"16.6","Brain RNA - cerebral cortex [nTPM]":"24.8","Brain RNA - hippocampal formation [nTPM]":"23.9","Brain RNA - hypothalamus [nTPM]":"22.7","Brain RNA - medulla oblongata [nTPM]":"20.5","Brain RNA - midbrain [nTPM]":"20.3","Brain RNA - pons [nTPM]":"21.7","Brain RNA - spinal cord [nTPM]":"16.8","Brain RNA - thalamus [nTPM]":"23.1","Brain RNA - white matter [nTPM]":"19.9","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.7","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"13.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"15.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.2","Single Cell Type RNA - dendritic cells [nTPM]":"21.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"17.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.0","Single Cell Type RNA - Endothelial cells [nTPM]":"10.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"9.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.5","Single Cell Type RNA - Fibroblasts [nTPM]":"20.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.8","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"16.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"62.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.5","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.5","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"20.1","Single Cell Type RNA - Muller glia cells [nTPM]":"15.8","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.0","Single Cell Type RNA - Paneth cells [nTPM]":"11.0","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"20.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.3","Single Cell Type RNA - Spermatocytes [nTPM]":"4.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.9","Single Cell Type RNA - T-cells [nTPM]":"21.6","Single Cell Type RNA - Theca cells [nTPM]":"23.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.2","Single Cell Type RNA - Urothelial cells [nTPM]":"7.8"},{"Gene":"C1QTNF5","Gene synonym":["CTRP5","DKFZp586B0621","LORD"],"Ensembl":"ENSG00000223953","Gene description":"C1q and TNF related 5","Uniprot":["Q9BXJ0"],"Chromosome":"11","Position":"119338942-119340940","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"4.7","Endothelial cells":"1.5","Exocrine glandular cells":"1.1","Fibroblasts":"3.6","Gastric mucus-secreting cells":"1.5","Smooth muscle cells":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"17.7","fHDF\/TERT166":"14.7","HHSteC":"35.8","hTERT-RPE1":"28.5","HUVEC TERT2":"54.7","TIME":"50.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025607","HPA038604"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":219000000,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025607":null,"HPA038604":"AB_2676110"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"51.9","Tissue RNA - adrenal gland [nTPM]":"13.4","Tissue RNA - amygdala [nTPM]":"19.1","Tissue RNA - appendix [nTPM]":"12.9","Tissue RNA - basal ganglia [nTPM]":"20.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"36.6","Tissue RNA - cerebellum [nTPM]":"20.3","Tissue RNA - cerebral cortex [nTPM]":"20.7","Tissue RNA - cervix [nTPM]":"38.4","Tissue RNA - choroid plexus [nTPM]":"25.5","Tissue RNA - colon [nTPM]":"23.0","Tissue RNA - duodenum [nTPM]":"14.9","Tissue RNA - endometrium 1 [nTPM]":"50.7","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"11.5","Tissue RNA - fallopian tube [nTPM]":"27.2","Tissue RNA - gallbladder [nTPM]":"45.5","Tissue RNA - heart muscle [nTPM]":"36.1","Tissue RNA - hippocampal formation [nTPM]":"17.3","Tissue RNA - hypothalamus [nTPM]":"19.8","Tissue RNA - kidney [nTPM]":"42.4","Tissue RNA - liver [nTPM]":"11.1","Tissue RNA - lung [nTPM]":"42.0","Tissue RNA - lymph node [nTPM]":"8.9","Tissue RNA - medulla oblongata [nTPM]":"21.8","Tissue RNA - midbrain [nTPM]":"22.2","Tissue RNA - ovary [nTPM]":"11.3","Tissue RNA - pancreas [nTPM]":"18.8","Tissue RNA - parathyroid gland [nTPM]":"6.8","Tissue RNA - pituitary gland [nTPM]":"14.8","Tissue RNA - placenta [nTPM]":"13.6","Tissue RNA - pons [nTPM]":"20.4","Tissue RNA - prostate [nTPM]":"19.5","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"16.9","Tissue RNA - seminal vesicle [nTPM]":"8.7","Tissue RNA - skeletal muscle [nTPM]":"8.8","Tissue RNA - skin 1 [nTPM]":"20.4","Tissue RNA - small intestine [nTPM]":"24.2","Tissue RNA - smooth muscle [nTPM]":"26.8","Tissue RNA - spinal cord [nTPM]":"21.7","Tissue RNA - spleen [nTPM]":"32.3","Tissue RNA - stomach 1 [nTPM]":"27.1","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"27.5","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"32.0","Tissue RNA - tongue [nTPM]":"15.2","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"31.6","Tissue RNA - vagina [nTPM]":"20.8","Tissue RNA - white matter [nTPM]":"21.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"3.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"17.7","Cell RNA - ASC TERT1 [nTPM]":"4.9","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"4.6","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.7","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"2.0","Cell RNA - fHDF\/TERT166 [nTPM]":"14.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"35.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"8.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"28.5","Cell RNA - HUVEC TERT2 [nTPM]":"54.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"2.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"4.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"6.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.1","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"50.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"19.1","Brain RNA - basal ganglia [nTPM]":"20.8","Brain RNA - cerebellum [nTPM]":"20.3","Brain RNA - cerebral cortex [nTPM]":"20.7","Brain RNA - hippocampal formation [nTPM]":"17.3","Brain RNA - hypothalamus [nTPM]":"19.8","Brain RNA - medulla oblongata [nTPM]":"21.8","Brain RNA - midbrain [nTPM]":"22.2","Brain RNA - pons [nTPM]":"20.4","Brain RNA - spinal cord [nTPM]":"21.7","Brain RNA - thalamus [nTPM]":"27.5","Brain RNA - white matter [nTPM]":"21.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"C2","Gene synonym":[],"Ensembl":"ENSG00000166278","Gene description":"Complement C2","Uniprot":["P06681"],"Chromosome":"6","Position":"31897785-31945672","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"477.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 2":"142.4","Hepatocytes":"380.3","Hofbauer cells":"282.7","Kupffer cells":"99.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"100.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"21.1","non-classical monocyte":"25.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"monocytes":"25.9"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Karpas-707":"284.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016775"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016775":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.64e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"42.6","Tissue RNA - adrenal gland [nTPM]":"12.1","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"27.6","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"3.2","Tissue RNA - breast [nTPM]":"11.7","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"8.1","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"14.3","Tissue RNA - duodenum [nTPM]":"16.7","Tissue RNA - endometrium 1 [nTPM]":"7.0","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"12.0","Tissue RNA - gallbladder [nTPM]":"23.0","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"23.2","Tissue RNA - liver [nTPM]":"477.9","Tissue RNA - lung [nTPM]":"80.0","Tissue RNA - lymph node [nTPM]":"27.8","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"48.4","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"13.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"5.8","Tissue RNA - small intestine [nTPM]":"30.2","Tissue RNA - smooth muscle [nTPM]":"23.6","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"46.3","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"5.5","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"12.5","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"6.8","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"52.8","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"284.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"16.5","Cell RNA - RPMI-8226 [nTPM]":"3.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"31.6","Cell RNA - U-698 [nTPM]":"2.7","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"5.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"21.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"25.9","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"142.4","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"380.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"282.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"99.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"32.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"7.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.5","Single Cell Type RNA - Paneth cells [nTPM]":"33.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"55.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.8","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"C3","Gene synonym":["ARMD9","C3a","C3b","CPAMD1"],"Ensembl":"ENSG00000125730","Gene description":"Complement C3","Uniprot":["P01024"],"Chromosome":"19","Position":"6677704-6730562","Protein class":["Candidate cardiovascular disease genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Complement pathway","Fatty acid metabolism","Immunity","Inflammatory response","Innate immunity","Lipid metabolism"],"Molecular function":null,"Disease involvement":["Age-related macular degeneration","Disease variant","FDA approved drug targets","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"liver":"4761.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"4512.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"1213.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"non-classical monocyte":"13.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"monocytes":"13.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"BJ hTERT+":"357.8","EFO-21":"738.6","Hep G2":"795.3","HSkMC":"534.8","SiHa":"209.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003563","CAB004209","HPA020432"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1260000000000,"Blood concentration - Conc. blood MS [pg\/L]":"200000000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004209":"AB_627277","HPA003563":"AB_1847117","HPA020432":"AB_1847118"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Tissue RNA - adipose tissue [nTPM]":"585.2","Tissue RNA - adrenal gland [nTPM]":"286.5","Tissue RNA - amygdala [nTPM]":"46.0","Tissue RNA - appendix [nTPM]":"194.3","Tissue RNA - basal ganglia [nTPM]":"53.7","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"213.9","Tissue RNA - cerebellum [nTPM]":"47.8","Tissue RNA - cerebral cortex [nTPM]":"46.0","Tissue RNA - cervix [nTPM]":"237.5","Tissue RNA - choroid plexus [nTPM]":"31.5","Tissue RNA - colon [nTPM]":"128.9","Tissue RNA - duodenum [nTPM]":"22.9","Tissue RNA - endometrium 1 [nTPM]":"82.9","Tissue RNA - epididymis [nTPM]":"41.1","Tissue RNA - esophagus [nTPM]":"76.4","Tissue RNA - fallopian tube [nTPM]":"350.3","Tissue RNA - gallbladder [nTPM]":"354.9","Tissue RNA - heart muscle [nTPM]":"221.6","Tissue RNA - hippocampal formation [nTPM]":"36.5","Tissue RNA - hypothalamus [nTPM]":"81.8","Tissue RNA - kidney [nTPM]":"51.4","Tissue RNA - liver [nTPM]":"4761.3","Tissue RNA - lung [nTPM]":"176.0","Tissue RNA - lymph node [nTPM]":"68.2","Tissue RNA - medulla oblongata [nTPM]":"143.3","Tissue RNA - midbrain [nTPM]":"99.2","Tissue RNA - ovary [nTPM]":"228.1","Tissue RNA - pancreas [nTPM]":"182.7","Tissue RNA - parathyroid gland [nTPM]":"17.9","Tissue RNA - pituitary gland [nTPM]":"21.8","Tissue RNA - placenta [nTPM]":"17.7","Tissue RNA - pons [nTPM]":"116.4","Tissue RNA - prostate [nTPM]":"35.4","Tissue RNA - rectum [nTPM]":"76.5","Tissue RNA - retina [nTPM]":"11.7","Tissue RNA - salivary gland [nTPM]":"155.6","Tissue RNA - seminal vesicle [nTPM]":"57.4","Tissue RNA - skeletal muscle [nTPM]":"36.6","Tissue RNA - skin 1 [nTPM]":"51.4","Tissue RNA - small intestine [nTPM]":"156.4","Tissue RNA - smooth muscle [nTPM]":"123.0","Tissue RNA - spinal cord [nTPM]":"89.9","Tissue RNA - spleen [nTPM]":"7.1","Tissue RNA - stomach 1 [nTPM]":"107.9","Tissue RNA - testis [nTPM]":"41.1","Tissue RNA - thalamus [nTPM]":"103.4","Tissue RNA - thymus [nTPM]":"34.1","Tissue RNA - thyroid gland [nTPM]":"92.4","Tissue RNA - tongue [nTPM]":"52.0","Tissue RNA - tonsil [nTPM]":"126.4","Tissue RNA - urinary bladder [nTPM]":"363.3","Tissue RNA - vagina [nTPM]":"101.3","Tissue RNA - white matter [nTPM]":"121.9","Cell RNA - A-431 [nTPM]":"65.0","Cell RNA - A549 [nTPM]":"23.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"10.8","Cell RNA - ASC TERT1 [nTPM]":"36.0","Cell RNA - BEWO [nTPM]":"74.7","Cell RNA - BJ [nTPM]":"5.2","Cell RNA - BJ hTERT+ [nTPM]":"357.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"3.6","Cell RNA - CAPAN-2 [nTPM]":"49.5","Cell RNA - Daudi [nTPM]":"1.9","Cell RNA - EFO-21 [nTPM]":"738.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"54.2","Cell RNA - HaCaT [nTPM]":"46.6","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"43.1","Cell RNA - HBF TERT88 [nTPM]":"6.9","Cell RNA - HDLM-2 [nTPM]":"24.0","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"3.1","Cell RNA - HeLa [nTPM]":"31.2","Cell RNA - Hep G2 [nTPM]":"795.3","Cell RNA - HHSteC [nTPM]":"16.3","Cell RNA - HL-60 [nTPM]":"6.2","Cell RNA - HMC-1 [nTPM]":"9.1","Cell RNA - HSkMC [nTPM]":"534.8","Cell RNA - hTCEpi [nTPM]":"12.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.8","Cell RNA - hTERT-HME1 [nTPM]":"27.3","Cell RNA - hTERT-RPE1 [nTPM]":"9.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"2.1","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"1.6","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"5.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"32.1","Cell RNA - RT4 [nTPM]":"6.2","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"209.5","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"17.2","Cell RNA - THP-1 [nTPM]":"8.8","Cell RNA - TIME [nTPM]":"3.5","Cell RNA - U-138 MG [nTPM]":"5.7","Cell RNA - U-2 OS [nTPM]":"7.4","Cell RNA - U-2197 [nTPM]":"4.8","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"1.6","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"75.1","Cell RNA - U-937 [nTPM]":"4.5","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"46.0","Brain RNA - basal ganglia [nTPM]":"53.7","Brain RNA - cerebellum [nTPM]":"47.8","Brain RNA - cerebral cortex [nTPM]":"46.0","Brain RNA - hippocampal formation [nTPM]":"36.5","Brain RNA - hypothalamus [nTPM]":"81.8","Brain RNA - medulla oblongata [nTPM]":"143.3","Brain RNA - midbrain [nTPM]":"99.2","Brain RNA - pons [nTPM]":"116.4","Brain RNA - spinal cord [nTPM]":"89.9","Brain RNA - thalamus [nTPM]":"103.4","Brain RNA - white matter [nTPM]":"121.9","Single Cell Type RNA - Adipocytes [nTPM]":"36.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"473.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"29.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"141.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"783.5","Single Cell Type RNA - Club cells [nTPM]":"422.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"494.1","Single Cell Type RNA - Early spermatids [nTPM]":"45.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"63.5","Single Cell Type RNA - Endothelial cells [nTPM]":"26.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"209.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"136.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"482.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"57.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"124.9","Single Cell Type RNA - Hepatocytes [nTPM]":"4512.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"164.5","Single Cell Type RNA - Langerhans cells [nTPM]":"44.8","Single Cell Type RNA - Late spermatids [nTPM]":"97.5","Single Cell Type RNA - Leydig cells [nTPM]":"226.2","Single Cell Type RNA - Macrophages [nTPM]":"45.1","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"70.3","Single Cell Type RNA - monocytes [nTPM]":"14.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"376.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"53.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"177.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.1","Single Cell Type RNA - Spermatocytes [nTPM]":"4.0","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - T-cells [nTPM]":"15.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"38.2"},{"Gene":"C8orf37","Gene synonym":["BBS21","CORD16","FAP418","FLJ30600","MOT25","RP64"],"Ensembl":"ENSG00000156172","Gene description":"Chromosome 8 open reading frame 37","Uniprot":["Q96NL8"],"Chromosome":"8","Position":"95244913-95269201","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Bardet-Biedl syndrome","Ciliopathy","Cone-rod dystrophy","Disease variant","Obesity","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024198"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane","Cell Junctions"],"Antibody RRID":{"HPA024198":"AB_1845775"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.63e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.7","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"2.4","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"3.9","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"1.7","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"3.5","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"1.5","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"1.8","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"2.8","Cell RNA - A549 [nTPM]":"4.5","Cell RNA - AF22 [nTPM]":"3.6","Cell RNA - AN3-CA [nTPM]":"1.9","Cell RNA - ASC diff [nTPM]":"1.2","Cell RNA - ASC TERT1 [nTPM]":"3.3","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"1.2","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"5.6","Cell RNA - EFO-21 [nTPM]":"2.8","Cell RNA - fHDF\/TERT166 [nTPM]":"2.0","Cell RNA - GAMG [nTPM]":"3.8","Cell RNA - HaCaT [nTPM]":"2.3","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"3.1","Cell RNA - HBF TERT88 [nTPM]":"3.3","Cell RNA - HDLM-2 [nTPM]":"1.8","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"4.4","Cell RNA - HeLa [nTPM]":"2.7","Cell RNA - Hep G2 [nTPM]":"2.0","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"5.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.9","Cell RNA - HUVEC TERT2 [nTPM]":"2.3","Cell RNA - JURKAT [nTPM]":"3.3","Cell RNA - K-562 [nTPM]":"2.3","Cell RNA - Karpas-707 [nTPM]":"3.2","Cell RNA - LHCN-M2 [nTPM]":"2.0","Cell RNA - MCF7 [nTPM]":"2.1","Cell RNA - MOLT-4 [nTPM]":"4.8","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"5.6","Cell RNA - PC-3 [nTPM]":"3.0","Cell RNA - REH [nTPM]":"2.5","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"3.4","Cell RNA - RT4 [nTPM]":"1.2","Cell RNA - SCLC-21H [nTPM]":"3.5","Cell RNA - SH-SY5Y [nTPM]":"3.4","Cell RNA - SiHa [nTPM]":"2.5","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"2.1","Cell RNA - SuSa [nTPM]":"2.7","Cell RNA - T-47d [nTPM]":"4.2","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"2.0","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"2.4","Cell RNA - U-2197 [nTPM]":"1.6","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"2.9","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"3.8","Cell RNA - U-87 MG [nTPM]":"3.6","Cell RNA - U-937 [nTPM]":"2.1","Cell RNA - WM-115 [nTPM]":"2.4","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"1.7","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"1.8","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"10.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.9","Single Cell Type RNA - Fibroblasts [nTPM]":"2.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.3","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"8.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"1.8","Single Cell Type RNA - Muller glia cells [nTPM]":"5.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"6.0","Single Cell Type RNA - Spermatogonia [nTPM]":"3.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"3.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"C9orf72","Gene synonym":["DENND9","DENNL72","MGC23980"],"Ensembl":"ENSG00000147894","Gene description":"C9orf72-SMCR8 complex subunit","Uniprot":["Q96LT7"],"Chromosome":"9","Position":"27535640-27573866","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Amyotrophic lateral sclerosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"127.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"24.3","classical monocyte":"32.0","intermediate monocyte":"44.7","myeloid DC":"25.2","neutrophil":"34.3","non-classical monocyte":"36.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"25.2","granulocytes":"34.3","monocytes":"44.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023873"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Midbody ring","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Midbody ring"],"Antibody RRID":{"HPA023873":"AB_1845834"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"12.1","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"16.6","Tissue RNA - basal ganglia [nTPM]":"9.5","Tissue RNA - bone marrow [nTPM]":"25.3","Tissue RNA - breast [nTPM]":"9.4","Tissue RNA - cerebellum [nTPM]":"21.0","Tissue RNA - cerebral cortex [nTPM]":"12.5","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"12.4","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"12.0","Tissue RNA - epididymis [nTPM]":"11.3","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"10.2","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"9.7","Tissue RNA - hypothalamus [nTPM]":"13.5","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"16.0","Tissue RNA - lung [nTPM]":"17.7","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"24.2","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"6.9","Tissue RNA - pituitary gland [nTPM]":"16.2","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"14.2","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"31.3","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"14.9","Tissue RNA - skin 1 [nTPM]":"8.8","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"12.4","Tissue RNA - spleen [nTPM]":"16.8","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"17.6","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"11.1","Tissue RNA - thyroid gland [nTPM]":"13.1","Tissue RNA - tongue [nTPM]":"9.9","Tissue RNA - tonsil [nTPM]":"8.8","Tissue RNA - urinary bladder [nTPM]":"9.2","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"14.5","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"3.7","Cell RNA - AF22 [nTPM]":"28.7","Cell RNA - AN3-CA [nTPM]":"4.4","Cell RNA - ASC diff [nTPM]":"5.7","Cell RNA - ASC TERT1 [nTPM]":"7.0","Cell RNA - BEWO [nTPM]":"4.4","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.8","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"1.4","Cell RNA - Daudi [nTPM]":"10.2","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"5.3","Cell RNA - GAMG [nTPM]":"7.5","Cell RNA - HaCaT [nTPM]":"3.1","Cell RNA - HAP1 [nTPM]":"9.4","Cell RNA - HBEC3-KT [nTPM]":"7.2","Cell RNA - HBF TERT88 [nTPM]":"2.5","Cell RNA - HDLM-2 [nTPM]":"19.8","Cell RNA - HEK 293 [nTPM]":"3.6","Cell RNA - HEL [nTPM]":"4.9","Cell RNA - HeLa [nTPM]":"11.0","Cell RNA - Hep G2 [nTPM]":"3.0","Cell RNA - HHSteC [nTPM]":"8.9","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"5.2","Cell RNA - HSkMC [nTPM]":"7.3","Cell RNA - hTCEpi [nTPM]":"8.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"16.1","Cell RNA - hTERT-RPE1 [nTPM]":"3.5","Cell RNA - HUVEC TERT2 [nTPM]":"7.6","Cell RNA - JURKAT [nTPM]":"11.1","Cell RNA - K-562 [nTPM]":"9.8","Cell RNA - Karpas-707 [nTPM]":"18.6","Cell RNA - LHCN-M2 [nTPM]":"4.3","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"6.6","Cell RNA - NB-4 [nTPM]":"5.0","Cell RNA - NTERA-2 [nTPM]":"14.2","Cell RNA - OE19 [nTPM]":"6.8","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"2.4","Cell RNA - RH-30 [nTPM]":"9.5","Cell RNA - RPMI-8226 [nTPM]":"5.1","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"3.3","Cell RNA - SCLC-21H [nTPM]":"9.9","Cell RNA - SH-SY5Y [nTPM]":"24.4","Cell RNA - SiHa [nTPM]":"4.0","Cell RNA - SK-BR-3 [nTPM]":"4.4","Cell RNA - SK-MEL-30 [nTPM]":"3.7","Cell RNA - SuSa [nTPM]":"10.9","Cell RNA - T-47d [nTPM]":"3.7","Cell RNA - THP-1 [nTPM]":"2.9","Cell RNA - TIME [nTPM]":"6.6","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"14.5","Cell RNA - U-2197 [nTPM]":"8.6","Cell RNA - U-251 MG [nTPM]":"4.0","Cell RNA - U-266\/70 [nTPM]":"4.8","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"6.8","Cell RNA - U-87 MG [nTPM]":"11.4","Cell RNA - U-937 [nTPM]":"11.0","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"24.3","Blood RNA - classical monocyte [nTPM]":"32.0","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"44.7","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"25.2","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.9","Blood RNA - neutrophil [nTPM]":"34.3","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"36.9","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"4.0","Blood RNA - total PBMC [nTPM]":"10.0","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"9.5","Brain RNA - cerebellum [nTPM]":"21.0","Brain RNA - cerebral cortex [nTPM]":"12.5","Brain RNA - hippocampal formation [nTPM]":"9.7","Brain RNA - hypothalamus [nTPM]":"13.5","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"12.4","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"14.5","Single Cell Type RNA - Adipocytes [nTPM]":"15.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.7","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"43.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"50.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"22.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"15.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.2","Single Cell Type RNA - dendritic cells [nTPM]":"11.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"94.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.8","Single Cell Type RNA - Endothelial cells [nTPM]":"15.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"18.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"57.6","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"18.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"9.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.8","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"58.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"71.9","Single Cell Type RNA - Langerhans cells [nTPM]":"127.8","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"94.8","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"58.2","Single Cell Type RNA - Muller glia cells [nTPM]":"45.2","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"60.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.6","Single Cell Type RNA - Paneth cells [nTPM]":"11.1","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"10.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"80.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.6","Single Cell Type RNA - Spermatocytes [nTPM]":"29.2","Single Cell Type RNA - Spermatogonia [nTPM]":"20.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.6","Single Cell Type RNA - T-cells [nTPM]":"18.2","Single Cell Type RNA - Theca cells [nTPM]":"7.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.1","Single Cell Type RNA - Urothelial cells [nTPM]":"37.6"},{"Gene":"CA4","Gene synonym":["CAIV","Car4","RP17"],"Ensembl":"ENSG00000167434","Gene description":"Carbonic anhydrase 4","Uniprot":["P22748"],"Chromosome":"17","Position":"60149942-60170899","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant","FDA approved drug targets","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"263.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Adipocytes":"704.2","Distal enterocytes":"1289.3","Paneth cells":"2368.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"7.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"99.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"995","RNA blood lineage specific nTPM":{"granulocytes":"99.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"1.1"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"300.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011089","HPA017258"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA011089":"AB_1845996","HPA017258":"AB_1845997"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"83.0","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"17.8","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"18.8","Tissue RNA - bone marrow [nTPM]":"19.5","Tissue RNA - breast [nTPM]":"80.9","Tissue RNA - cerebellum [nTPM]":"86.8","Tissue RNA - cerebral cortex [nTPM]":"34.2","Tissue RNA - cervix [nTPM]":"12.7","Tissue RNA - choroid plexus [nTPM]":"13.9","Tissue RNA - colon [nTPM]":"263.6","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"51.9","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"5.0","Tissue RNA - gallbladder [nTPM]":"38.3","Tissue RNA - heart muscle [nTPM]":"55.2","Tissue RNA - hippocampal formation [nTPM]":"22.8","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"47.6","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"87.2","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"13.4","Tissue RNA - midbrain [nTPM]":"17.8","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"31.8","Tissue RNA - parathyroid gland [nTPM]":"16.9","Tissue RNA - pituitary gland [nTPM]":"15.7","Tissue RNA - placenta [nTPM]":"8.6","Tissue RNA - pons [nTPM]":"22.8","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"172.6","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"10.4","Tissue RNA - seminal vesicle [nTPM]":"36.9","Tissue RNA - skeletal muscle [nTPM]":"30.5","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"11.2","Tissue RNA - smooth muscle [nTPM]":"2.7","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"16.0","Tissue RNA - stomach 1 [nTPM]":"10.0","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"15.1","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"74.6","Tissue RNA - tongue [nTPM]":"42.3","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"6.2","Tissue RNA - vagina [nTPM]":"5.6","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"15.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"99.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"17.8","Brain RNA - basal ganglia [nTPM]":"18.8","Brain RNA - cerebellum [nTPM]":"86.8","Brain RNA - cerebral cortex [nTPM]":"34.2","Brain RNA - hippocampal formation [nTPM]":"22.8","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"13.4","Brain RNA - midbrain [nTPM]":"17.8","Brain RNA - pons [nTPM]":"22.8","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"15.1","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"704.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1289.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.0","Single Cell Type RNA - Endothelial cells [nTPM]":"88.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"23.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"2368.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"72.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.4","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"CA8","Gene synonym":["CALS","CARP"],"Ensembl":"ENSG00000178538","Gene description":"Carbonic anhydrase 8","Uniprot":["P35219"],"Chromosome":"8","Position":"60185412-60281400","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.3","parathyroid gland":"40.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"92.7","Enteroendocrine cells":"35.2","Gastric mucus-secreting cells":"40.2","Oligodendrocyte precursor cells":"129.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"7.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"24","RNA blood cell specific nTPM":{"basophil":"76.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"granulocytes":"76.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"10.1","JURKAT":"11.0","K-562":"20.3","NB-4":"12.3","OE19":"17.4"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"38","RNA mouse brain regional specific nTPM":{"cerebellum":"1260.5"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"9","RNA pig brain regional specific nTPM":{"cerebellum":"86.3"},"Antibody":["HPA024748","CAB025545","CAB047309"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025545":null,"CAB047309":null,"HPA024748":"AB_1846003"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.79e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"5.8","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"18.3","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"4.3","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"10.2","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"4.4","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"5.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"40.1","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"6.2","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"3.7","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"5.1","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"2.3","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"4.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.4","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"10.1","Cell RNA - HEL [nTPM]":"4.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.6","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"11.0","Cell RNA - K-562 [nTPM]":"20.3","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"3.3","Cell RNA - NB-4 [nTPM]":"12.3","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"17.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.0","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"5.5","Blood RNA - basophil [nTPM]":"76.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"5.8","Brain RNA - cerebellum [nTPM]":"18.3","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"4.4","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"5.1","Brain RNA - white matter [nTPM]":"4.0","Single Cell Type RNA - Adipocytes [nTPM]":"22.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"92.7","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"8.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - dendritic cells [nTPM]":"10.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.1","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.4","Single Cell Type RNA - Endothelial cells [nTPM]":"16.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.2","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"129.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.6","Single Cell Type RNA - Paneth cells [nTPM]":"3.5","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"14.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"3.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"CABP2","Gene synonym":["DFNB93"],"Ensembl":"ENSG00000167791","Gene description":"Calcium binding protein 2","Uniprot":["Q9NPB3"],"Chromosome":"11","Position":"67518912-67524517","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Hearing","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"retina":"7.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Bipolar cells":"100.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"22","RNA mouse brain regional specific nTPM":{"cerebellum":"9.3"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"100.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CABP4","Gene synonym":["CSNB2B"],"Ensembl":"ENSG00000175544","Gene description":"Calcium binding protein 4","Uniprot":["P57796"],"Chromosome":"11","Position":"67452406-67461752","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"retina":"68.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"141.8","Rod photoreceptor cells":"254.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"12.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HMC-1":"19.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"1.6","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"68.2","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"1.5","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"4.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"4.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"19.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.9","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"4.0","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"12.1","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.6","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.5","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"17.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"141.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.9","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"28.9","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"254.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"CACNA1A","Gene synonym":["APCA","CACNL1A4","Cav2.1","EA2","FHM","HPCA","MHP","MHP1","SCA6"],"Ensembl":"ENSG00000141837","Gene description":"Calcium voltage-gated channel subunit alpha1 A","Uniprot":["O00555"],"Chromosome":"19","Position":"13206442-13633025","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"99.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Bipolar cells":"101.4","Enteroendocrine cells":"214.1","Excitatory neurons":"318.3","Horizontal cells":"249.0","Inhibitory neurons":"372.1","Oligodendrocyte precursor cells":"271.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"99.3","cerebral cortex":"30.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SCLC-21H":"45.1","U-87 MG":"23.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064258","HPA068138","HPA071902"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA064258":"AB_2685229","HPA068138":null,"HPA071902":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.32e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"15.4","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"15.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"99.3","Tissue RNA - cerebral cortex [nTPM]":"30.4","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"3.2","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"15.1","Tissue RNA - hypothalamus [nTPM]":"6.8","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"7.2","Tissue RNA - midbrain [nTPM]":"11.2","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"4.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"10.6","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"7.1","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.7","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"9.4","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"2.7","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"15.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"6.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.2","Cell RNA - BJ hTERT+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"5.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"2.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"7.2","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"1.4","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"45.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"23.9","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"15.4","Brain RNA - basal ganglia [nTPM]":"15.8","Brain RNA - cerebellum [nTPM]":"99.3","Brain RNA - cerebral cortex [nTPM]":"30.4","Brain RNA - hippocampal formation [nTPM]":"15.1","Brain RNA - hypothalamus [nTPM]":"6.8","Brain RNA - medulla oblongata [nTPM]":"7.2","Brain RNA - midbrain [nTPM]":"11.2","Brain RNA - pons [nTPM]":"10.6","Brain RNA - spinal cord [nTPM]":"9.4","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"15.2","Single Cell Type RNA - Adipocytes [nTPM]":"7.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"31.3","Single Cell Type RNA - B-cells [nTPM]":"9.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"101.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"27.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.3","Single Cell Type RNA - Endothelial cells [nTPM]":"6.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"214.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"318.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"5.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"249.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"372.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"28.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"3.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"271.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"2.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"CACNA1B","Gene synonym":["CACNL1A5","CACNN","Cav2.2"],"Ensembl":"ENSG00000148408","Gene description":"Calcium voltage-gated channel subunit alpha1 B","Uniprot":["Q00975"],"Chromosome":"9","Position":"137877782-138124624","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.2","pituitary gland":"6.8","testis":"5.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Excitatory neurons":"388.8","Inhibitory neurons":"330.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"amygdala":"5.9","basal ganglia":"7.8","cerebral cortex":"10.2","hippocampal formation":"3.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SCLC-21H":"19.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022919","HPA044347"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA022919":null,"HPA044347":"AB_10960837"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"2.8","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"10.2","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"3.1","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"3.5","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"19.5","Cell RNA - SH-SY5Y [nTPM]":"3.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"10.2","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"43.4","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"11.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"388.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"330.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"8.2","Single Cell Type RNA - Spermatogonia [nTPM]":"9.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CACNA1E","Gene synonym":["BII","CACH6","CACNL1A6","Cav2.3"],"Ensembl":"ENSG00000198216","Gene description":"Calcium voltage-gated channel subunit alpha1 E","Uniprot":["Q15878"],"Chromosome":"1","Position":"181317690-181808084","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"brain":"42.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"188.7","Inhibitory neurons":"116.0","Oligodendrocyte precursor cells":"73.9","Oligodendrocytes":"34.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"1.6","NB-4":"1.0","NTERA-2":"1.1","U-266\/70":"2.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042515","CAB079032"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments","Cytosol"],"Antibody RRID":{"CAB079032":null,"HPA042515":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"33.5","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"30.5","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"34.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"42.8","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.6","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"2.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"33.5","Brain RNA - basal ganglia [nTPM]":"30.5","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"34.6","Brain RNA - hippocampal formation [nTPM]":"42.8","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"188.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"116.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"73.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CACNA1F","Gene synonym":["AIED","Cav1.4","CORDX3","CSNB2","CSNB2A","CSNBX2","JM8","JMC8","OA2"],"Ensembl":"ENSG00000102001","Gene description":"Calcium voltage-gated channel subunit alpha1 F","Uniprot":["O60840"],"Chromosome":"X","Position":"49205063-49233371","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Cone-rod dystrophy","Congenital stationary night blindness","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"53","RNA tissue specific nTPM":{"retina":"125.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Bipolar cells":"66.5","Cone photoreceptor cells":"133.5","Rod photoreceptor cells":"97.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"1.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068379"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA068379":"AB_2732782"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"1.9","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"125.3","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"66.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"133.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"2.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"97.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CACNA1G","Gene synonym":["Cav3.1","NBR13"],"Ensembl":"ENSG00000006283","Gene description":"Calcium voltage-gated channel subunit alpha1 G","Uniprot":["O43497"],"Chromosome":"17","Position":"50560715-50627474","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"37.5","cervix":"9.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"176.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.6","testis cancer":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"9.2","GAMG":"3.2","HeLa":"3.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004714"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004714":"AB_1078368"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"5.3","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"19.3","Tissue RNA - cerebral cortex [nTPM]":"9.9","Tissue RNA - cervix [nTPM]":"9.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"3.4","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"3.6","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"10.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"19.4","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"8.8","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"12.8","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"37.5","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"9.2","Cell RNA - AF22 [nTPM]":"2.1","Cell RNA - AN3-CA [nTPM]":"2.4","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"3.2","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"3.2","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"1.8","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"2.5","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"5.3","Brain RNA - cerebellum [nTPM]":"19.3","Brain RNA - cerebral cortex [nTPM]":"9.9","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"10.3","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"19.4","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"12.8","Brain RNA - thalamus [nTPM]":"37.5","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"176.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CACNA1H","Gene synonym":["Cav3.2"],"Ensembl":"ENSG00000196557","Gene description":"Calcium voltage-gated channel subunit alpha1 H","Uniprot":["O95180"],"Chromosome":"16","Position":"1153106-1221771","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"107.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"22.8","Late spermatids":"15.5","Peritubular cells":"25.9","Sertoli cells":"26.3","Smooth muscle cells":"22.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"17.9","AN3-CA":"25.4","MCF7":"48.3","OE19":"16.0","T-47d":"13.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039125"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA039125":"AB_10795578"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.12e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.6","Tissue RNA - adrenal gland [nTPM]":"28.0","Tissue RNA - amygdala [nTPM]":"13.6","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"24.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"2.1","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"26.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"107.7","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"57.3","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"37.8","Tissue RNA - gallbladder [nTPM]":"10.3","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"11.0","Tissue RNA - hypothalamus [nTPM]":"8.1","Tissue RNA - kidney [nTPM]":"14.1","Tissue RNA - liver [nTPM]":"13.4","Tissue RNA - lung [nTPM]":"11.8","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"3.8","Tissue RNA - ovary [nTPM]":"80.1","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"3.6","Tissue RNA - pituitary gland [nTPM]":"45.9","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"28.0","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"27.5","Tissue RNA - skeletal muscle [nTPM]":"6.2","Tissue RNA - skin 1 [nTPM]":"19.4","Tissue RNA - small intestine [nTPM]":"22.3","Tissue RNA - smooth muscle [nTPM]":"15.6","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"27.5","Tissue RNA - testis [nTPM]":"19.4","Tissue RNA - thalamus [nTPM]":"13.5","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"11.0","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"57.0","Tissue RNA - vagina [nTPM]":"17.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"17.9","Cell RNA - AF22 [nTPM]":"3.0","Cell RNA - AN3-CA [nTPM]":"25.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"11.0","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"4.5","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.0","Cell RNA - K-562 [nTPM]":"4.9","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"48.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"9.4","Cell RNA - OE19 [nTPM]":"16.0","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"13.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"10.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.6","Brain RNA - basal ganglia [nTPM]":"24.5","Brain RNA - cerebellum [nTPM]":"2.1","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"11.0","Brain RNA - hypothalamus [nTPM]":"8.1","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"3.8","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"13.5","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.7","Single Cell Type RNA - Early spermatids [nTPM]":"7.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"7.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"15.5","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"CACNA2D4","Gene synonym":[],"Ensembl":"ENSG00000151062","Gene description":"Calcium voltage-gated channel auxiliary subunit alpha2delta 4","Uniprot":["Q7Z3S7"],"Chromosome":"12","Position":"1791963-1918666","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"39","RNA tissue specific nTPM":{"retina":"20.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"56.3","Cone photoreceptor cells":"156.4","Early spermatids":"56.3","Late spermatids":"117.6","Rod photoreceptor cells":"98.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"2.9","monocytes":"4.4","T-cells":"4.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"4.7","HL-60":"2.8","HMC-1":"14.0","NB-4":"6.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031952"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031952":"AB_10600798"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"20.2","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"4.7","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"2.8","Cell RNA - HMC-1 [nTPM]":"14.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"6.6","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.8","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"4.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"2.1","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"4.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"56.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"156.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"5.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"56.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"29.2","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"117.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"23.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"17.3","Single Cell Type RNA - Muller glia cells [nTPM]":"6.9","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"3.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"98.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"9.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"8.6","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"CACNB4","Gene synonym":["EJM4"],"Ensembl":"ENSG00000182389","Gene description":"Calcium voltage-gated channel auxiliary subunit beta 4","Uniprot":["O00305"],"Chromosome":"2","Position":"151832771-152099167","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"16.4","skin 1":"7.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"495.6","Inhibitory neurons":"470.7","Microglial cells":"136.8","Oligodendrocyte precursor cells":"155.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"3.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"3.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"4.1","HMC-1":"20.2","U-937":"5.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015601"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015601":"AB_1845873"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"12.0","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"16.4","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"7.3","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"3.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"20.2","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"1.1","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"3.3","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.8","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"5.9","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"12.0","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"16.4","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.3","Single Cell Type RNA - Astrocytes [nTPM]":"80.6","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"9.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"495.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"7.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"84.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.4","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"470.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"136.8","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"2.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"155.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"2.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"6.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"16.3"},{"Gene":"CAD","Gene synonym":["GATD4"],"Ensembl":"ENSG00000084774","Gene description":"Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase","Uniprot":["P27708"],"Chromosome":"2","Position":"27217369-27243943","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pyrimidine biosynthesis"],"Molecular function":["Allosteric enzyme","Hydrolase","Ligase","Multifunctional enzyme","Transferase"],"Disease involvement":["Cancer-related genes","Congenital disorder of glycosylation","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007781","HPA065158","HPA069341"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB007781":"AB_562057","HPA065158":null,"HPA069341":"AB_2686125"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-11"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Tissue RNA - adipose tissue [nTPM]":"15.0","Tissue RNA - adrenal gland [nTPM]":"13.5","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"12.4","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"14.9","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"15.5","Tissue RNA - cervix [nTPM]":"19.8","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"16.5","Tissue RNA - duodenum [nTPM]":"8.5","Tissue RNA - endometrium 1 [nTPM]":"23.8","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"19.2","Tissue RNA - fallopian tube [nTPM]":"19.3","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"12.3","Tissue RNA - hypothalamus [nTPM]":"12.8","Tissue RNA - kidney [nTPM]":"18.0","Tissue RNA - liver [nTPM]":"27.8","Tissue RNA - lung [nTPM]":"12.3","Tissue RNA - lymph node [nTPM]":"14.9","Tissue RNA - medulla oblongata [nTPM]":"13.8","Tissue RNA - midbrain [nTPM]":"13.5","Tissue RNA - ovary [nTPM]":"22.3","Tissue RNA - pancreas [nTPM]":"22.3","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"18.7","Tissue RNA - placenta [nTPM]":"7.5","Tissue RNA - pons [nTPM]":"14.5","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"12.3","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"10.3","Tissue RNA - skin 1 [nTPM]":"18.7","Tissue RNA - small intestine [nTPM]":"16.1","Tissue RNA - smooth muscle [nTPM]":"11.9","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"20.1","Tissue RNA - stomach 1 [nTPM]":"14.0","Tissue RNA - testis [nTPM]":"22.2","Tissue RNA - thalamus [nTPM]":"14.2","Tissue RNA - thymus [nTPM]":"11.6","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"10.5","Tissue RNA - urinary bladder [nTPM]":"16.9","Tissue RNA - vagina [nTPM]":"15.8","Tissue RNA - white matter [nTPM]":"15.2","Cell RNA - A-431 [nTPM]":"75.2","Cell RNA - A549 [nTPM]":"66.4","Cell RNA - AF22 [nTPM]":"28.9","Cell RNA - AN3-CA [nTPM]":"58.4","Cell RNA - ASC diff [nTPM]":"46.1","Cell RNA - ASC TERT1 [nTPM]":"37.6","Cell RNA - BEWO [nTPM]":"22.9","Cell RNA - BJ [nTPM]":"31.0","Cell RNA - BJ hTERT+ [nTPM]":"21.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.0","Cell RNA - CACO-2 [nTPM]":"75.7","Cell RNA - CAPAN-2 [nTPM]":"29.2","Cell RNA - Daudi [nTPM]":"66.4","Cell RNA - EFO-21 [nTPM]":"27.4","Cell RNA - fHDF\/TERT166 [nTPM]":"28.5","Cell RNA - GAMG [nTPM]":"29.6","Cell RNA - HaCaT [nTPM]":"41.4","Cell RNA - HAP1 [nTPM]":"85.7","Cell RNA - HBEC3-KT [nTPM]":"41.1","Cell RNA - HBF TERT88 [nTPM]":"28.5","Cell RNA - HDLM-2 [nTPM]":"43.8","Cell RNA - HEK 293 [nTPM]":"69.2","Cell RNA - HEL [nTPM]":"95.2","Cell RNA - HeLa [nTPM]":"55.0","Cell RNA - Hep G2 [nTPM]":"40.0","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"75.7","Cell RNA - HMC-1 [nTPM]":"46.2","Cell RNA - HSkMC [nTPM]":"28.8","Cell RNA - hTCEpi [nTPM]":"33.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.7","Cell RNA - hTERT-HME1 [nTPM]":"63.0","Cell RNA - hTERT-RPE1 [nTPM]":"17.8","Cell RNA - HUVEC TERT2 [nTPM]":"41.6","Cell RNA - JURKAT [nTPM]":"60.6","Cell RNA - K-562 [nTPM]":"68.3","Cell RNA - Karpas-707 [nTPM]":"36.0","Cell RNA - LHCN-M2 [nTPM]":"34.2","Cell RNA - MCF7 [nTPM]":"74.8","Cell RNA - MOLT-4 [nTPM]":"48.7","Cell RNA - NB-4 [nTPM]":"112.0","Cell RNA - NTERA-2 [nTPM]":"69.7","Cell RNA - OE19 [nTPM]":"31.3","Cell RNA - PC-3 [nTPM]":"49.7","Cell RNA - REH [nTPM]":"84.0","Cell RNA - RH-30 [nTPM]":"86.5","Cell RNA - RPMI-8226 [nTPM]":"69.5","Cell RNA - RPTEC TERT1 [nTPM]":"28.6","Cell RNA - RT4 [nTPM]":"37.6","Cell RNA - SCLC-21H [nTPM]":"57.9","Cell RNA - SH-SY5Y [nTPM]":"29.1","Cell RNA - SiHa [nTPM]":"43.3","Cell RNA - SK-BR-3 [nTPM]":"30.5","Cell RNA - SK-MEL-30 [nTPM]":"37.4","Cell RNA - SuSa [nTPM]":"21.3","Cell RNA - T-47d [nTPM]":"23.9","Cell RNA - THP-1 [nTPM]":"31.3","Cell RNA - TIME [nTPM]":"37.7","Cell RNA - U-138 MG [nTPM]":"57.7","Cell RNA - U-2 OS [nTPM]":"47.5","Cell RNA - U-2197 [nTPM]":"45.5","Cell RNA - U-251 MG [nTPM]":"63.5","Cell RNA - U-266\/70 [nTPM]":"74.0","Cell RNA - U-266\/84 [nTPM]":"51.8","Cell RNA - U-698 [nTPM]":"135.2","Cell RNA - U-87 MG [nTPM]":"23.3","Cell RNA - U-937 [nTPM]":"71.7","Cell RNA - WM-115 [nTPM]":"51.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"5.2","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"2.8","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"15.5","Brain RNA - hippocampal formation [nTPM]":"12.3","Brain RNA - hypothalamus [nTPM]":"12.8","Brain RNA - medulla oblongata [nTPM]":"13.8","Brain RNA - midbrain [nTPM]":"13.5","Brain RNA - pons [nTPM]":"14.5","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"14.2","Brain RNA - white matter [nTPM]":"15.2","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"5.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"10.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - dendritic cells [nTPM]":"3.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.6","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.6","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.3","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"16.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"7.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.6","Single Cell Type RNA - Spermatogonia [nTPM]":"12.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"5.1","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"CAMTA1","Gene synonym":["KIAA0833"],"Ensembl":"ENSG00000171735","Gene description":"Calmodulin binding transcription activator 1","Uniprot":["Q9Y6Y1"],"Chromosome":"1","Position":"6785454-7769706","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036342","HPA036343"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036342":"AB_2675072","HPA036343":"AB_10671839"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.10e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-3"},"Tissue RNA - adipose tissue [nTPM]":"37.1","Tissue RNA - adrenal gland [nTPM]":"43.7","Tissue RNA - amygdala [nTPM]":"56.2","Tissue RNA - appendix [nTPM]":"23.6","Tissue RNA - basal ganglia [nTPM]":"55.3","Tissue RNA - bone marrow [nTPM]":"26.5","Tissue RNA - breast [nTPM]":"38.7","Tissue RNA - cerebellum [nTPM]":"63.4","Tissue RNA - cerebral cortex [nTPM]":"75.8","Tissue RNA - cervix [nTPM]":"33.0","Tissue RNA - choroid plexus [nTPM]":"29.4","Tissue RNA - colon [nTPM]":"71.8","Tissue RNA - duodenum [nTPM]":"52.8","Tissue RNA - endometrium 1 [nTPM]":"40.1","Tissue RNA - epididymis [nTPM]":"81.7","Tissue RNA - esophagus [nTPM]":"37.5","Tissue RNA - fallopian tube [nTPM]":"36.0","Tissue RNA - gallbladder [nTPM]":"30.4","Tissue RNA - heart muscle [nTPM]":"114.0","Tissue RNA - hippocampal formation [nTPM]":"55.0","Tissue RNA - hypothalamus [nTPM]":"68.6","Tissue RNA - kidney [nTPM]":"68.4","Tissue RNA - liver [nTPM]":"70.5","Tissue RNA - lung [nTPM]":"36.7","Tissue RNA - lymph node [nTPM]":"27.3","Tissue RNA - medulla oblongata [nTPM]":"69.4","Tissue RNA - midbrain [nTPM]":"66.0","Tissue RNA - ovary [nTPM]":"35.4","Tissue RNA - pancreas [nTPM]":"26.4","Tissue RNA - parathyroid gland [nTPM]":"43.3","Tissue RNA - pituitary gland [nTPM]":"35.5","Tissue RNA - placenta [nTPM]":"26.4","Tissue RNA - pons [nTPM]":"68.7","Tissue RNA - prostate [nTPM]":"47.0","Tissue RNA - rectum [nTPM]":"48.5","Tissue RNA - retina [nTPM]":"68.2","Tissue RNA - salivary gland [nTPM]":"50.5","Tissue RNA - seminal vesicle [nTPM]":"50.5","Tissue RNA - skeletal muscle [nTPM]":"101.6","Tissue RNA - skin 1 [nTPM]":"26.0","Tissue RNA - small intestine [nTPM]":"41.1","Tissue RNA - smooth muscle [nTPM]":"42.4","Tissue RNA - spinal cord [nTPM]":"61.5","Tissue RNA - spleen [nTPM]":"30.7","Tissue RNA - stomach 1 [nTPM]":"45.2","Tissue RNA - testis [nTPM]":"44.5","Tissue RNA - thalamus [nTPM]":"66.4","Tissue RNA - thymus [nTPM]":"31.9","Tissue RNA - thyroid gland [nTPM]":"52.0","Tissue RNA - tongue [nTPM]":"104.7","Tissue RNA - tonsil [nTPM]":"33.5","Tissue RNA - urinary bladder [nTPM]":"56.5","Tissue RNA - vagina [nTPM]":"35.2","Tissue RNA - white matter [nTPM]":"60.8","Cell RNA - A-431 [nTPM]":"67.6","Cell RNA - A549 [nTPM]":"37.2","Cell RNA - AF22 [nTPM]":"101.2","Cell RNA - AN3-CA [nTPM]":"51.7","Cell RNA - ASC diff [nTPM]":"51.2","Cell RNA - ASC TERT1 [nTPM]":"77.6","Cell RNA - BEWO [nTPM]":"28.4","Cell RNA - BJ [nTPM]":"71.0","Cell RNA - BJ hTERT+ [nTPM]":"54.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"75.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"63.1","Cell RNA - CACO-2 [nTPM]":"45.1","Cell RNA - CAPAN-2 [nTPM]":"83.2","Cell RNA - Daudi [nTPM]":"55.5","Cell RNA - EFO-21 [nTPM]":"54.6","Cell RNA - fHDF\/TERT166 [nTPM]":"75.2","Cell RNA - GAMG [nTPM]":"50.3","Cell RNA - HaCaT [nTPM]":"40.8","Cell RNA - HAP1 [nTPM]":"53.6","Cell RNA - HBEC3-KT [nTPM]":"73.7","Cell RNA - HBF TERT88 [nTPM]":"106.5","Cell RNA - HDLM-2 [nTPM]":"41.8","Cell RNA - HEK 293 [nTPM]":"57.8","Cell RNA - HEL [nTPM]":"62.7","Cell RNA - HeLa [nTPM]":"85.1","Cell RNA - Hep G2 [nTPM]":"89.6","Cell RNA - HHSteC [nTPM]":"83.0","Cell RNA - HL-60 [nTPM]":"48.2","Cell RNA - HMC-1 [nTPM]":"43.6","Cell RNA - HSkMC [nTPM]":"52.5","Cell RNA - hTCEpi [nTPM]":"50.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"54.5","Cell RNA - hTERT-HME1 [nTPM]":"83.0","Cell RNA - hTERT-RPE1 [nTPM]":"64.6","Cell RNA - HUVEC TERT2 [nTPM]":"85.1","Cell RNA - JURKAT [nTPM]":"77.7","Cell RNA - K-562 [nTPM]":"44.8","Cell RNA - Karpas-707 [nTPM]":"73.2","Cell RNA - LHCN-M2 [nTPM]":"87.9","Cell RNA - MCF7 [nTPM]":"65.0","Cell RNA - MOLT-4 [nTPM]":"64.6","Cell RNA - NB-4 [nTPM]":"130.9","Cell RNA - NTERA-2 [nTPM]":"70.2","Cell RNA - OE19 [nTPM]":"85.2","Cell RNA - PC-3 [nTPM]":"43.2","Cell RNA - REH [nTPM]":"42.5","Cell RNA - RH-30 [nTPM]":"90.2","Cell RNA - RPMI-8226 [nTPM]":"123.7","Cell RNA - RPTEC TERT1 [nTPM]":"103.4","Cell RNA - RT4 [nTPM]":"38.7","Cell RNA - SCLC-21H [nTPM]":"104.2","Cell RNA - SH-SY5Y [nTPM]":"83.7","Cell RNA - SiHa [nTPM]":"50.4","Cell RNA - SK-BR-3 [nTPM]":"74.1","Cell RNA - SK-MEL-30 [nTPM]":"113.9","Cell RNA - SuSa [nTPM]":"72.3","Cell RNA - T-47d [nTPM]":"40.2","Cell RNA - THP-1 [nTPM]":"59.4","Cell RNA - TIME [nTPM]":"50.1","Cell RNA - U-138 MG [nTPM]":"53.1","Cell RNA - U-2 OS [nTPM]":"44.9","Cell RNA - U-2197 [nTPM]":"55.3","Cell RNA - U-251 MG [nTPM]":"45.2","Cell RNA - U-266\/70 [nTPM]":"55.2","Cell RNA - U-266\/84 [nTPM]":"74.3","Cell RNA - U-698 [nTPM]":"153.2","Cell RNA - U-87 MG [nTPM]":"79.6","Cell RNA - U-937 [nTPM]":"107.4","Cell RNA - WM-115 [nTPM]":"30.7","Blood RNA - basophil [nTPM]":"80.1","Blood RNA - classical monocyte [nTPM]":"74.7","Blood RNA - eosinophil [nTPM]":"70.5","Blood RNA - gdT-cell [nTPM]":"25.8","Blood RNA - intermediate monocyte [nTPM]":"48.5","Blood RNA - MAIT T-cell [nTPM]":"28.3","Blood RNA - memory B-cell [nTPM]":"48.1","Blood RNA - memory CD4 T-cell [nTPM]":"39.8","Blood RNA - memory CD8 T-cell [nTPM]":"32.0","Blood RNA - myeloid DC [nTPM]":"73.4","Blood RNA - naive B-cell [nTPM]":"41.8","Blood RNA - naive CD4 T-cell [nTPM]":"32.2","Blood RNA - naive CD8 T-cell [nTPM]":"28.1","Blood RNA - neutrophil [nTPM]":"15.4","Blood RNA - NK-cell [nTPM]":"26.7","Blood RNA - non-classical monocyte [nTPM]":"37.9","Blood RNA - plasmacytoid DC [nTPM]":"77.5","Blood RNA - T-reg [nTPM]":"45.6","Blood RNA - total PBMC [nTPM]":"46.3","Brain RNA - amygdala [nTPM]":"56.2","Brain RNA - basal ganglia [nTPM]":"55.3","Brain RNA - cerebellum [nTPM]":"63.4","Brain RNA - cerebral cortex [nTPM]":"75.8","Brain RNA - hippocampal formation [nTPM]":"55.0","Brain RNA - hypothalamus [nTPM]":"68.6","Brain RNA - medulla oblongata [nTPM]":"69.4","Brain RNA - midbrain [nTPM]":"66.0","Brain RNA - pons [nTPM]":"68.7","Brain RNA - spinal cord [nTPM]":"61.5","Brain RNA - thalamus [nTPM]":"66.4","Brain RNA - white matter [nTPM]":"60.8","Single Cell Type RNA - Adipocytes [nTPM]":"142.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"48.8","Single Cell Type RNA - Astrocytes [nTPM]":"314.7","Single Cell Type RNA - B-cells [nTPM]":"74.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"309.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"340.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"306.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"169.0","Single Cell Type RNA - Bipolar cells [nTPM]":"106.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"231.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"283.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"565.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"101.5","Single Cell Type RNA - Club cells [nTPM]":"135.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"191.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"252.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"69.8","Single Cell Type RNA - dendritic cells [nTPM]":"44.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"198.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"418.7","Single Cell Type RNA - Ductal cells [nTPM]":"180.1","Single Cell Type RNA - Early spermatids [nTPM]":"166.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"84.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"80.3","Single Cell Type RNA - Endothelial cells [nTPM]":"155.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"130.8","Single Cell Type RNA - Erythroid cells [nTPM]":"81.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"346.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"206.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"144.9","Single Cell Type RNA - Fibroblasts [nTPM]":"134.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"63.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"99.8","Single Cell Type RNA - granulocytes [nTPM]":"55.2","Single Cell Type RNA - Granulosa cells [nTPM]":"205.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"106.1","Single Cell Type RNA - Hepatocytes [nTPM]":"239.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"106.3","Single Cell Type RNA - Horizontal cells [nTPM]":"158.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"479.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"185.8","Single Cell Type RNA - Ionocytes [nTPM]":"223.8","Single Cell Type RNA - Kupffer cells [nTPM]":"95.5","Single Cell Type RNA - Langerhans cells [nTPM]":"254.0","Single Cell Type RNA - Late spermatids [nTPM]":"137.9","Single Cell Type RNA - Leydig cells [nTPM]":"76.4","Single Cell Type RNA - Macrophages [nTPM]":"122.0","Single Cell Type RNA - Melanocytes [nTPM]":"238.3","Single Cell Type RNA - Microglial cells [nTPM]":"117.1","Single Cell Type RNA - monocytes [nTPM]":"172.9","Single Cell Type RNA - Muller glia cells [nTPM]":"112.3","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"330.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"227.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"184.2","Single Cell Type RNA - Paneth cells [nTPM]":"234.5","Single Cell Type RNA - Peritubular cells [nTPM]":"128.6","Single Cell Type RNA - Plasma cells [nTPM]":"87.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"486.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"251.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"750.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"117.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"156.2","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"91.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"233.2","Single Cell Type RNA - Spermatocytes [nTPM]":"151.0","Single Cell Type RNA - Spermatogonia [nTPM]":"211.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"158.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"282.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.1","Single Cell Type RNA - T-cells [nTPM]":"68.2","Single Cell Type RNA - Theca cells [nTPM]":"137.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"186.5","Single Cell Type RNA - Urothelial cells [nTPM]":"413.7"},{"Gene":"CAPN1","Gene synonym":["CANP","CANPL1","muCANP","muCL"],"Ensembl":"ENSG00000014216","Gene description":"Calpain 1","Uniprot":["P07384"],"Chromosome":"11","Position":"65180566-65212006","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"276.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RT4":"516.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005992"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9100000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA005992":"AB_1845924"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.30e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.06e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"44.8","Tissue RNA - adrenal gland [nTPM]":"43.1","Tissue RNA - amygdala [nTPM]":"27.8","Tissue RNA - appendix [nTPM]":"51.9","Tissue RNA - basal ganglia [nTPM]":"26.1","Tissue RNA - bone marrow [nTPM]":"66.5","Tissue RNA - breast [nTPM]":"48.4","Tissue RNA - cerebellum [nTPM]":"29.7","Tissue RNA - cerebral cortex [nTPM]":"30.1","Tissue RNA - cervix [nTPM]":"80.9","Tissue RNA - choroid plexus [nTPM]":"28.3","Tissue RNA - colon [nTPM]":"78.6","Tissue RNA - duodenum [nTPM]":"80.4","Tissue RNA - endometrium 1 [nTPM]":"56.3","Tissue RNA - epididymis [nTPM]":"27.5","Tissue RNA - esophagus [nTPM]":"276.2","Tissue RNA - fallopian tube [nTPM]":"92.3","Tissue RNA - gallbladder [nTPM]":"55.5","Tissue RNA - heart muscle [nTPM]":"53.1","Tissue RNA - hippocampal formation [nTPM]":"27.7","Tissue RNA - hypothalamus [nTPM]":"33.0","Tissue RNA - kidney [nTPM]":"53.1","Tissue RNA - liver [nTPM]":"44.3","Tissue RNA - lung [nTPM]":"56.9","Tissue RNA - lymph node [nTPM]":"57.0","Tissue RNA - medulla oblongata [nTPM]":"41.4","Tissue RNA - midbrain [nTPM]":"31.5","Tissue RNA - ovary [nTPM]":"44.5","Tissue RNA - pancreas [nTPM]":"71.7","Tissue RNA - parathyroid gland [nTPM]":"36.6","Tissue RNA - pituitary gland [nTPM]":"40.8","Tissue RNA - placenta [nTPM]":"56.2","Tissue RNA - pons [nTPM]":"43.4","Tissue RNA - prostate [nTPM]":"62.1","Tissue RNA - rectum [nTPM]":"57.6","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"118.7","Tissue RNA - seminal vesicle [nTPM]":"67.4","Tissue RNA - skeletal muscle [nTPM]":"84.8","Tissue RNA - skin 1 [nTPM]":"125.1","Tissue RNA - small intestine [nTPM]":"88.1","Tissue RNA - smooth muscle [nTPM]":"45.3","Tissue RNA - spinal cord [nTPM]":"33.9","Tissue RNA - spleen [nTPM]":"50.2","Tissue RNA - stomach 1 [nTPM]":"65.5","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"37.9","Tissue RNA - thymus [nTPM]":"49.5","Tissue RNA - thyroid gland [nTPM]":"71.5","Tissue RNA - tongue [nTPM]":"55.3","Tissue RNA - tonsil [nTPM]":"86.4","Tissue RNA - urinary bladder [nTPM]":"83.4","Tissue RNA - vagina [nTPM]":"117.4","Tissue RNA - white matter [nTPM]":"27.4","Cell RNA - A-431 [nTPM]":"285.6","Cell RNA - A549 [nTPM]":"147.9","Cell RNA - AF22 [nTPM]":"42.9","Cell RNA - AN3-CA [nTPM]":"97.2","Cell RNA - ASC diff [nTPM]":"77.9","Cell RNA - ASC TERT1 [nTPM]":"104.3","Cell RNA - BEWO [nTPM]":"127.0","Cell RNA - BJ [nTPM]":"84.1","Cell RNA - BJ hTERT+ [nTPM]":"144.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"103.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"74.9","Cell RNA - CACO-2 [nTPM]":"94.8","Cell RNA - CAPAN-2 [nTPM]":"250.2","Cell RNA - Daudi [nTPM]":"71.2","Cell RNA - EFO-21 [nTPM]":"136.0","Cell RNA - fHDF\/TERT166 [nTPM]":"179.3","Cell RNA - GAMG [nTPM]":"111.1","Cell RNA - HaCaT [nTPM]":"409.8","Cell RNA - HAP1 [nTPM]":"60.9","Cell RNA - HBEC3-KT [nTPM]":"366.9","Cell RNA - HBF TERT88 [nTPM]":"32.2","Cell RNA - HDLM-2 [nTPM]":"76.4","Cell RNA - HEK 293 [nTPM]":"44.1","Cell RNA - HEL [nTPM]":"170.8","Cell RNA - HeLa [nTPM]":"80.4","Cell RNA - Hep G2 [nTPM]":"93.7","Cell RNA - HHSteC [nTPM]":"76.2","Cell RNA - HL-60 [nTPM]":"40.6","Cell RNA - HMC-1 [nTPM]":"228.0","Cell RNA - HSkMC [nTPM]":"107.3","Cell RNA - hTCEpi [nTPM]":"196.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"85.9","Cell RNA - hTERT-HME1 [nTPM]":"43.2","Cell RNA - hTERT-RPE1 [nTPM]":"92.6","Cell RNA - HUVEC TERT2 [nTPM]":"178.5","Cell RNA - JURKAT [nTPM]":"50.6","Cell RNA - K-562 [nTPM]":"103.1","Cell RNA - Karpas-707 [nTPM]":"55.9","Cell RNA - LHCN-M2 [nTPM]":"87.4","Cell RNA - MCF7 [nTPM]":"181.8","Cell RNA - MOLT-4 [nTPM]":"83.1","Cell RNA - NB-4 [nTPM]":"130.6","Cell RNA - NTERA-2 [nTPM]":"120.5","Cell RNA - OE19 [nTPM]":"145.2","Cell RNA - PC-3 [nTPM]":"133.8","Cell RNA - REH [nTPM]":"80.7","Cell RNA - RH-30 [nTPM]":"43.0","Cell RNA - RPMI-8226 [nTPM]":"43.2","Cell RNA - RPTEC TERT1 [nTPM]":"138.1","Cell RNA - RT4 [nTPM]":"516.5","Cell RNA - SCLC-21H [nTPM]":"76.2","Cell RNA - SH-SY5Y [nTPM]":"55.7","Cell RNA - SiHa [nTPM]":"87.4","Cell RNA - SK-BR-3 [nTPM]":"331.4","Cell RNA - SK-MEL-30 [nTPM]":"80.3","Cell RNA - SuSa [nTPM]":"45.8","Cell RNA - T-47d [nTPM]":"142.8","Cell RNA - THP-1 [nTPM]":"77.9","Cell RNA - TIME [nTPM]":"147.1","Cell RNA - U-138 MG [nTPM]":"73.1","Cell RNA - U-2 OS [nTPM]":"50.5","Cell RNA - U-2197 [nTPM]":"159.0","Cell RNA - U-251 MG [nTPM]":"38.5","Cell RNA - U-266\/70 [nTPM]":"33.8","Cell RNA - U-266\/84 [nTPM]":"26.9","Cell RNA - U-698 [nTPM]":"86.6","Cell RNA - U-87 MG [nTPM]":"127.5","Cell RNA - U-937 [nTPM]":"48.8","Cell RNA - WM-115 [nTPM]":"82.3","Blood RNA - basophil [nTPM]":"87.6","Blood RNA - classical monocyte [nTPM]":"57.5","Blood RNA - eosinophil [nTPM]":"77.9","Blood RNA - gdT-cell [nTPM]":"39.4","Blood RNA - intermediate monocyte [nTPM]":"51.2","Blood RNA - MAIT T-cell [nTPM]":"31.0","Blood RNA - memory B-cell [nTPM]":"30.8","Blood RNA - memory CD4 T-cell [nTPM]":"30.7","Blood RNA - memory CD8 T-cell [nTPM]":"35.8","Blood RNA - myeloid DC [nTPM]":"48.4","Blood RNA - naive B-cell [nTPM]":"31.7","Blood RNA - naive CD4 T-cell [nTPM]":"17.6","Blood RNA - naive CD8 T-cell [nTPM]":"24.9","Blood RNA - neutrophil [nTPM]":"33.1","Blood RNA - NK-cell [nTPM]":"34.8","Blood RNA - non-classical monocyte [nTPM]":"30.4","Blood RNA - plasmacytoid DC [nTPM]":"38.1","Blood RNA - T-reg [nTPM]":"35.9","Blood RNA - total PBMC [nTPM]":"74.8","Brain RNA - amygdala [nTPM]":"27.8","Brain RNA - basal ganglia [nTPM]":"26.1","Brain RNA - cerebellum [nTPM]":"29.7","Brain RNA - cerebral cortex [nTPM]":"30.1","Brain RNA - hippocampal formation [nTPM]":"27.7","Brain RNA - hypothalamus [nTPM]":"33.0","Brain RNA - medulla oblongata [nTPM]":"41.4","Brain RNA - midbrain [nTPM]":"31.5","Brain RNA - pons [nTPM]":"43.4","Brain RNA - spinal cord [nTPM]":"33.9","Brain RNA - thalamus [nTPM]":"37.9","Brain RNA - white matter [nTPM]":"27.4","Single Cell Type RNA - Adipocytes [nTPM]":"27.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.9","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"39.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"59.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"127.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"120.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"56.9","Single Cell Type RNA - Bipolar cells [nTPM]":"10.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"44.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"74.4","Single Cell Type RNA - Club cells [nTPM]":"81.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"77.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"238.5","Single Cell Type RNA - dendritic cells [nTPM]":"61.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"184.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"180.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.3","Single Cell Type RNA - Endothelial cells [nTPM]":"31.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.3","Single Cell Type RNA - Erythroid cells [nTPM]":"58.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"115.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"111.7","Single Cell Type RNA - Fibroblasts [nTPM]":"39.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"57.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"58.2","Single Cell Type RNA - granulocytes [nTPM]":"46.9","Single Cell Type RNA - Granulosa cells [nTPM]":"48.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.9","Single Cell Type RNA - Hepatocytes [nTPM]":"36.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"88.7","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"76.9","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"51.2","Single Cell Type RNA - Langerhans cells [nTPM]":"34.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"43.5","Single Cell Type RNA - Macrophages [nTPM]":"67.1","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"112.7","Single Cell Type RNA - Muller glia cells [nTPM]":"38.5","Single Cell Type RNA - NK-cells [nTPM]":"61.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"179.4","Single Cell Type RNA - Paneth cells [nTPM]":"124.1","Single Cell Type RNA - Peritubular cells [nTPM]":"50.8","Single Cell Type RNA - Plasma cells [nTPM]":"17.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"78.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"155.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"34.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"71.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.2","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"102.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"68.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"196.6","Single Cell Type RNA - T-cells [nTPM]":"40.2","Single Cell Type RNA - Theca cells [nTPM]":"35.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"125.3","Single Cell Type RNA - Urothelial cells [nTPM]":"156.6"},{"Gene":"CAPN5","Gene synonym":["ADNIV","HTRA3","nCL-3","VRNI"],"Ensembl":"ENSG00000149260","Gene description":"Calpain 5","Uniprot":["O15484"],"Chromosome":"11","Position":"77066961-77126155","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"60.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"170.3","Gastric mucus-secreting cells":"80.0","Intestinal goblet cells":"89.8","Paneth cells":"72.6","Proximal enterocytes":"75.6","Undifferentiated cells":"69.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"1.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"106.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033237","HPA072319"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB033237":"AB_2069673","HPA072319":"AB_2686512"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.16e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"12.2","Tissue RNA - amygdala [nTPM]":"8.5","Tissue RNA - appendix [nTPM]":"10.9","Tissue RNA - basal ganglia [nTPM]":"7.9","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"8.6","Tissue RNA - cervix [nTPM]":"13.5","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"60.5","Tissue RNA - duodenum [nTPM]":"60.7","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"31.6","Tissue RNA - fallopian tube [nTPM]":"10.8","Tissue RNA - gallbladder [nTPM]":"36.3","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"15.1","Tissue RNA - liver [nTPM]":"52.1","Tissue RNA - lung [nTPM]":"4.8","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"11.7","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"13.2","Tissue RNA - pancreas [nTPM]":"5.6","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"5.1","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"16.0","Tissue RNA - rectum [nTPM]":"49.9","Tissue RNA - retina [nTPM]":"3.8","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"3.1","Tissue RNA - small intestine [nTPM]":"52.4","Tissue RNA - smooth muscle [nTPM]":"11.3","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"3.5","Tissue RNA - stomach 1 [nTPM]":"47.9","Tissue RNA - testis [nTPM]":"21.5","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"2.7","Tissue RNA - urinary bladder [nTPM]":"15.4","Tissue RNA - vagina [nTPM]":"10.5","Tissue RNA - white matter [nTPM]":"8.1","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"12.5","Cell RNA - AF22 [nTPM]":"8.6","Cell RNA - AN3-CA [nTPM]":"7.8","Cell RNA - ASC diff [nTPM]":"32.0","Cell RNA - ASC TERT1 [nTPM]":"30.4","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"11.8","Cell RNA - BJ hTERT+ [nTPM]":"22.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"3.6","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"7.7","Cell RNA - fHDF\/TERT166 [nTPM]":"24.5","Cell RNA - GAMG [nTPM]":"14.4","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"1.0","Cell RNA - HBF TERT88 [nTPM]":"6.4","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"2.1","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"7.9","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"16.1","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.6","Cell RNA - hTERT-HME1 [nTPM]":"5.2","Cell RNA - hTERT-RPE1 [nTPM]":"18.8","Cell RNA - HUVEC TERT2 [nTPM]":"14.4","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"26.9","Cell RNA - MCF7 [nTPM]":"19.9","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"6.6","Cell RNA - OE19 [nTPM]":"106.6","Cell RNA - PC-3 [nTPM]":"9.3","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"27.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"4.6","Cell RNA - RT4 [nTPM]":"16.4","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"13.5","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"2.7","Cell RNA - SK-MEL-30 [nTPM]":"5.9","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"23.9","Cell RNA - U-138 MG [nTPM]":"25.4","Cell RNA - U-2 OS [nTPM]":"12.3","Cell RNA - U-2197 [nTPM]":"34.8","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"13.1","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"5.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"8.5","Brain RNA - basal ganglia [nTPM]":"7.9","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"8.6","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"11.7","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"8.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"170.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.3","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"40.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"89.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.4","Single Cell Type RNA - Paneth cells [nTPM]":"72.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"75.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"5.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"69.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.4"},{"Gene":"CASR","Gene synonym":["FHH","GPRC2A","HHC","HHC1","NSHPT"],"Ensembl":"ENSG00000036828","Gene description":"Calcium sensing receptor","Uniprot":["P41180"],"Chromosome":"3","Position":"122183668-122291629","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"parathyroid gland":"654.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"25.6","Alveolar cells type 2":"20.2","Cholangiocytes":"27.1","Distal tubular cells":"13.7","Enteroendocrine cells":"11.5","Granulosa cells":"20.7","Respiratory ciliated cells":"15.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"pancreatic cancer":"5.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039686","HPA050335"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039686":"AB_10673536","HPA050335":"AB_2681092"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"22.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"654.4","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CCDC50","Gene synonym":["C3orf6","DFNA44","Ymer"],"Ensembl":"ENSG00000152492","Gene description":"Coiled-coil domain containing 50","Uniprot":["Q8IVM0"],"Chromosome":"3","Position":"191329085-191398659","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"363.7","Oligodendrocyte precursor cells":"365.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"630.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"630.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001336"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001336":"AB_1078421"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-1"},"Tissue RNA - adipose tissue [nTPM]":"63.2","Tissue RNA - adrenal gland [nTPM]":"28.3","Tissue RNA - amygdala [nTPM]":"19.6","Tissue RNA - appendix [nTPM]":"34.3","Tissue RNA - basal ganglia [nTPM]":"20.7","Tissue RNA - bone marrow [nTPM]":"10.3","Tissue RNA - breast [nTPM]":"30.6","Tissue RNA - cerebellum [nTPM]":"21.5","Tissue RNA - cerebral cortex [nTPM]":"19.1","Tissue RNA - cervix [nTPM]":"24.1","Tissue RNA - choroid plexus [nTPM]":"18.8","Tissue RNA - colon [nTPM]":"26.9","Tissue RNA - duodenum [nTPM]":"24.2","Tissue RNA - endometrium 1 [nTPM]":"33.0","Tissue RNA - epididymis [nTPM]":"24.8","Tissue RNA - esophagus [nTPM]":"27.9","Tissue RNA - fallopian tube [nTPM]":"24.3","Tissue RNA - gallbladder [nTPM]":"34.8","Tissue RNA - heart muscle [nTPM]":"39.7","Tissue RNA - hippocampal formation [nTPM]":"17.6","Tissue RNA - hypothalamus [nTPM]":"23.3","Tissue RNA - kidney [nTPM]":"32.4","Tissue RNA - liver [nTPM]":"56.5","Tissue RNA - lung [nTPM]":"31.6","Tissue RNA - lymph node [nTPM]":"42.2","Tissue RNA - medulla oblongata [nTPM]":"24.1","Tissue RNA - midbrain [nTPM]":"22.0","Tissue RNA - ovary [nTPM]":"46.2","Tissue RNA - pancreas [nTPM]":"35.1","Tissue RNA - parathyroid gland [nTPM]":"27.6","Tissue RNA - pituitary gland [nTPM]":"13.5","Tissue RNA - placenta [nTPM]":"34.9","Tissue RNA - pons [nTPM]":"24.1","Tissue RNA - prostate [nTPM]":"26.2","Tissue RNA - rectum [nTPM]":"25.4","Tissue RNA - retina [nTPM]":"11.8","Tissue RNA - salivary gland [nTPM]":"23.7","Tissue RNA - seminal vesicle [nTPM]":"33.3","Tissue RNA - skeletal muscle [nTPM]":"19.0","Tissue RNA - skin 1 [nTPM]":"18.4","Tissue RNA - small intestine [nTPM]":"25.8","Tissue RNA - smooth muscle [nTPM]":"48.1","Tissue RNA - spinal cord [nTPM]":"23.2","Tissue RNA - spleen [nTPM]":"45.0","Tissue RNA - stomach 1 [nTPM]":"24.3","Tissue RNA - testis [nTPM]":"29.6","Tissue RNA - thalamus [nTPM]":"21.3","Tissue RNA - thymus [nTPM]":"17.7","Tissue RNA - thyroid gland [nTPM]":"27.4","Tissue RNA - tongue [nTPM]":"26.1","Tissue RNA - tonsil [nTPM]":"41.0","Tissue RNA - urinary bladder [nTPM]":"36.7","Tissue RNA - vagina [nTPM]":"18.6","Tissue RNA - white matter [nTPM]":"24.7","Cell RNA - A-431 [nTPM]":"74.9","Cell RNA - A549 [nTPM]":"24.5","Cell RNA - AF22 [nTPM]":"93.6","Cell RNA - AN3-CA [nTPM]":"24.7","Cell RNA - ASC diff [nTPM]":"82.3","Cell RNA - ASC TERT1 [nTPM]":"72.1","Cell RNA - BEWO [nTPM]":"32.3","Cell RNA - BJ [nTPM]":"135.4","Cell RNA - BJ hTERT+ [nTPM]":"135.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"95.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"95.0","Cell RNA - CACO-2 [nTPM]":"52.6","Cell RNA - CAPAN-2 [nTPM]":"28.9","Cell RNA - Daudi [nTPM]":"14.6","Cell RNA - EFO-21 [nTPM]":"163.0","Cell RNA - fHDF\/TERT166 [nTPM]":"76.8","Cell RNA - GAMG [nTPM]":"70.6","Cell RNA - HaCaT [nTPM]":"83.6","Cell RNA - HAP1 [nTPM]":"75.6","Cell RNA - HBEC3-KT [nTPM]":"60.5","Cell RNA - HBF TERT88 [nTPM]":"141.9","Cell RNA - HDLM-2 [nTPM]":"109.0","Cell RNA - HEK 293 [nTPM]":"37.8","Cell RNA - HEL [nTPM]":"10.0","Cell RNA - HeLa [nTPM]":"31.7","Cell RNA - Hep G2 [nTPM]":"60.3","Cell RNA - HHSteC [nTPM]":"120.8","Cell RNA - HL-60 [nTPM]":"36.8","Cell RNA - HMC-1 [nTPM]":"37.8","Cell RNA - HSkMC [nTPM]":"58.2","Cell RNA - hTCEpi [nTPM]":"79.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"75.6","Cell RNA - hTERT-HME1 [nTPM]":"169.7","Cell RNA - hTERT-RPE1 [nTPM]":"82.2","Cell RNA - HUVEC TERT2 [nTPM]":"148.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"33.9","Cell RNA - Karpas-707 [nTPM]":"77.3","Cell RNA - LHCN-M2 [nTPM]":"85.4","Cell RNA - MCF7 [nTPM]":"26.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"23.1","Cell RNA - NTERA-2 [nTPM]":"33.2","Cell RNA - OE19 [nTPM]":"7.6","Cell RNA - PC-3 [nTPM]":"103.0","Cell RNA - REH [nTPM]":"56.3","Cell RNA - RH-30 [nTPM]":"51.9","Cell RNA - RPMI-8226 [nTPM]":"73.1","Cell RNA - RPTEC TERT1 [nTPM]":"104.3","Cell RNA - RT4 [nTPM]":"31.9","Cell RNA - SCLC-21H [nTPM]":"21.8","Cell RNA - SH-SY5Y [nTPM]":"33.2","Cell RNA - SiHa [nTPM]":"48.2","Cell RNA - SK-BR-3 [nTPM]":"51.6","Cell RNA - SK-MEL-30 [nTPM]":"95.8","Cell RNA - SuSa [nTPM]":"67.3","Cell RNA - T-47d [nTPM]":"35.6","Cell RNA - THP-1 [nTPM]":"32.9","Cell RNA - TIME [nTPM]":"153.3","Cell RNA - U-138 MG [nTPM]":"93.4","Cell RNA - U-2 OS [nTPM]":"78.4","Cell RNA - U-2197 [nTPM]":"68.4","Cell RNA - U-251 MG [nTPM]":"176.3","Cell RNA - U-266\/70 [nTPM]":"118.6","Cell RNA - U-266\/84 [nTPM]":"54.9","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"50.5","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"76.9","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"22.1","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"5.9","Blood RNA - intermediate monocyte [nTPM]":"20.8","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"128.5","Blood RNA - memory CD4 T-cell [nTPM]":"6.1","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"44.3","Blood RNA - naive B-cell [nTPM]":"76.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"24.0","Blood RNA - non-classical monocyte [nTPM]":"12.1","Blood RNA - plasmacytoid DC [nTPM]":"630.7","Blood RNA - T-reg [nTPM]":"22.1","Blood RNA - total PBMC [nTPM]":"18.0","Brain RNA - amygdala [nTPM]":"19.6","Brain RNA - basal ganglia [nTPM]":"20.7","Brain RNA - cerebellum [nTPM]":"21.5","Brain RNA - cerebral cortex [nTPM]":"19.1","Brain RNA - hippocampal formation [nTPM]":"17.6","Brain RNA - hypothalamus [nTPM]":"23.3","Brain RNA - medulla oblongata [nTPM]":"24.1","Brain RNA - midbrain [nTPM]":"22.0","Brain RNA - pons [nTPM]":"24.1","Brain RNA - spinal cord [nTPM]":"23.2","Brain RNA - thalamus [nTPM]":"21.3","Brain RNA - white matter [nTPM]":"24.7","Single Cell Type RNA - Adipocytes [nTPM]":"143.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.5","Single Cell Type RNA - Astrocytes [nTPM]":"40.5","Single Cell Type RNA - B-cells [nTPM]":"134.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"52.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"27.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"58.6","Single Cell Type RNA - Club cells [nTPM]":"34.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.1","Single Cell Type RNA - dendritic cells [nTPM]":"363.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"120.4","Single Cell Type RNA - Early spermatids [nTPM]":"183.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"97.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"58.1","Single Cell Type RNA - Endothelial cells [nTPM]":"134.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.8","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"78.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.3","Single Cell Type RNA - Fibroblasts [nTPM]":"66.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"79.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"58.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"175.6","Single Cell Type RNA - Hepatocytes [nTPM]":"79.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"84.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"41.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.8","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"59.4","Single Cell Type RNA - Langerhans cells [nTPM]":"78.3","Single Cell Type RNA - Late spermatids [nTPM]":"92.1","Single Cell Type RNA - Leydig cells [nTPM]":"69.3","Single Cell Type RNA - Macrophages [nTPM]":"61.4","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"98.4","Single Cell Type RNA - monocytes [nTPM]":"101.4","Single Cell Type RNA - Muller glia cells [nTPM]":"32.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"365.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"174.7","Single Cell Type RNA - Paneth cells [nTPM]":"33.9","Single Cell Type RNA - Peritubular cells [nTPM]":"75.6","Single Cell Type RNA - Plasma cells [nTPM]":"102.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"69.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"71.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.4","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"74.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.7","Single Cell Type RNA - Spermatocytes [nTPM]":"73.2","Single Cell Type RNA - Spermatogonia [nTPM]":"26.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.5","Single Cell Type RNA - T-cells [nTPM]":"22.4","Single Cell Type RNA - Theca cells [nTPM]":"49.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.7","Single Cell Type RNA - Urothelial cells [nTPM]":"62.4"},{"Gene":"CCDC88A","Gene synonym":["APE","FLJ10392","GIV","GRDN","HkRP1","KIAA1212"],"Ensembl":"ENSG00000115355","Gene description":"Coiled-coil domain containing 88A","Uniprot":["Q3V6T2"],"Chromosome":"2","Position":"55287842-55419895","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","DNA replication","Neurogenesis"],"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Epilepsy","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"80.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"634.4","Late spermatids":"699.8","Oligodendrocytes":"754.9","Spermatocytes":"429.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"7.4","classical monocyte":"7.2","intermediate monocyte":"7.0","myeloid DC":"11.3","non-classical monocyte":"6.8","plasmacytoid DC":"23.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"23.9","granulocytes":"7.4","monocytes":"7.2"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038101","HPA038102"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038101":"AB_10670654","HPA038102":"AB_2675833"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.06e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.98e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"9.7","Tissue RNA - amygdala [nTPM]":"48.4","Tissue RNA - appendix [nTPM]":"14.0","Tissue RNA - basal ganglia [nTPM]":"65.3","Tissue RNA - bone marrow [nTPM]":"15.6","Tissue RNA - breast [nTPM]":"8.4","Tissue RNA - cerebellum [nTPM]":"53.2","Tissue RNA - cerebral cortex [nTPM]":"77.6","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"29.6","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"9.8","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"9.2","Tissue RNA - hippocampal formation [nTPM]":"48.8","Tissue RNA - hypothalamus [nTPM]":"54.4","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"8.4","Tissue RNA - lung [nTPM]":"14.5","Tissue RNA - lymph node [nTPM]":"17.2","Tissue RNA - medulla oblongata [nTPM]":"54.8","Tissue RNA - midbrain [nTPM]":"60.8","Tissue RNA - ovary [nTPM]":"9.3","Tissue RNA - pancreas [nTPM]":"10.7","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"13.2","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"57.7","Tissue RNA - prostate [nTPM]":"5.9","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"26.3","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"7.3","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"7.1","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"48.8","Tissue RNA - spleen [nTPM]":"13.3","Tissue RNA - stomach 1 [nTPM]":"6.5","Tissue RNA - testis [nTPM]":"47.3","Tissue RNA - thalamus [nTPM]":"62.6","Tissue RNA - thymus [nTPM]":"18.8","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"9.6","Tissue RNA - tonsil [nTPM]":"15.1","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"80.9","Cell RNA - A-431 [nTPM]":"22.8","Cell RNA - A549 [nTPM]":"19.7","Cell RNA - AF22 [nTPM]":"45.2","Cell RNA - AN3-CA [nTPM]":"18.3","Cell RNA - ASC diff [nTPM]":"29.4","Cell RNA - ASC TERT1 [nTPM]":"24.3","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"32.3","Cell RNA - BJ hTERT+ [nTPM]":"30.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.6","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"12.0","Cell RNA - Daudi [nTPM]":"60.2","Cell RNA - EFO-21 [nTPM]":"19.5","Cell RNA - fHDF\/TERT166 [nTPM]":"32.6","Cell RNA - GAMG [nTPM]":"28.9","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"28.9","Cell RNA - HBEC3-KT [nTPM]":"19.3","Cell RNA - HBF TERT88 [nTPM]":"46.8","Cell RNA - HDLM-2 [nTPM]":"69.8","Cell RNA - HEK 293 [nTPM]":"16.8","Cell RNA - HEL [nTPM]":"41.4","Cell RNA - HeLa [nTPM]":"21.7","Cell RNA - Hep G2 [nTPM]":"28.6","Cell RNA - HHSteC [nTPM]":"12.6","Cell RNA - HL-60 [nTPM]":"70.7","Cell RNA - HMC-1 [nTPM]":"26.8","Cell RNA - HSkMC [nTPM]":"15.8","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.6","Cell RNA - hTERT-HME1 [nTPM]":"28.6","Cell RNA - hTERT-RPE1 [nTPM]":"27.1","Cell RNA - HUVEC TERT2 [nTPM]":"50.3","Cell RNA - JURKAT [nTPM]":"48.1","Cell RNA - K-562 [nTPM]":"44.9","Cell RNA - Karpas-707 [nTPM]":"95.9","Cell RNA - LHCN-M2 [nTPM]":"51.9","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"33.5","Cell RNA - NB-4 [nTPM]":"41.1","Cell RNA - NTERA-2 [nTPM]":"37.4","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"24.8","Cell RNA - REH [nTPM]":"39.7","Cell RNA - RH-30 [nTPM]":"71.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"22.9","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"23.5","Cell RNA - SH-SY5Y [nTPM]":"34.8","Cell RNA - SiHa [nTPM]":"57.4","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"28.9","Cell RNA - SuSa [nTPM]":"26.2","Cell RNA - T-47d [nTPM]":"1.1","Cell RNA - THP-1 [nTPM]":"20.2","Cell RNA - TIME [nTPM]":"34.9","Cell RNA - U-138 MG [nTPM]":"54.4","Cell RNA - U-2 OS [nTPM]":"36.5","Cell RNA - U-2197 [nTPM]":"36.6","Cell RNA - U-251 MG [nTPM]":"39.6","Cell RNA - U-266\/70 [nTPM]":"28.8","Cell RNA - U-266\/84 [nTPM]":"24.0","Cell RNA - U-698 [nTPM]":"25.8","Cell RNA - U-87 MG [nTPM]":"38.0","Cell RNA - U-937 [nTPM]":"56.2","Cell RNA - WM-115 [nTPM]":"23.7","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"7.2","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"7.0","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"11.3","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"6.8","Blood RNA - plasmacytoid DC [nTPM]":"23.9","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"48.4","Brain RNA - basal ganglia [nTPM]":"65.3","Brain RNA - cerebellum [nTPM]":"53.2","Brain RNA - cerebral cortex [nTPM]":"77.6","Brain RNA - hippocampal formation [nTPM]":"48.8","Brain RNA - hypothalamus [nTPM]":"54.4","Brain RNA - medulla oblongata [nTPM]":"54.8","Brain RNA - midbrain [nTPM]":"60.8","Brain RNA - pons [nTPM]":"57.7","Brain RNA - spinal cord [nTPM]":"48.8","Brain RNA - thalamus [nTPM]":"62.6","Brain RNA - white matter [nTPM]":"80.9","Single Cell Type RNA - Adipocytes [nTPM]":"35.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.9","Single Cell Type RNA - Astrocytes [nTPM]":"197.9","Single Cell Type RNA - B-cells [nTPM]":"25.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"225.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"52.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"12.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"90.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.2","Single Cell Type RNA - Early spermatids [nTPM]":"634.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"58.8","Single Cell Type RNA - Endothelial cells [nTPM]":"41.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"51.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"317.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.4","Single Cell Type RNA - Fibroblasts [nTPM]":"38.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.1","Single Cell Type RNA - granulocytes [nTPM]":"152.8","Single Cell Type RNA - Granulosa cells [nTPM]":"64.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"110.8","Single Cell Type RNA - Horizontal cells [nTPM]":"79.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"318.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"142.0","Single Cell Type RNA - Langerhans cells [nTPM]":"126.7","Single Cell Type RNA - Late spermatids [nTPM]":"699.8","Single Cell Type RNA - Leydig cells [nTPM]":"29.8","Single Cell Type RNA - Macrophages [nTPM]":"184.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"129.3","Single Cell Type RNA - monocytes [nTPM]":"236.1","Single Cell Type RNA - Muller glia cells [nTPM]":"109.8","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"296.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"754.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"114.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"61.9","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.4","Single Cell Type RNA - Spermatocytes [nTPM]":"429.0","Single Cell Type RNA - Spermatogonia [nTPM]":"95.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"22.4","Single Cell Type RNA - Theca cells [nTPM]":"82.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"2.8"},{"Gene":"CCDC88C","Gene synonym":["DAPLE","HkRP2","KIAA1509","SCA40"],"Ensembl":"ENSG00000015133","Gene description":"Coiled-coil domain containing 88C","Uniprot":["Q9P219"],"Chromosome":"14","Position":"91271323-91417844","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"33.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"80.1","NK-cells":"142.2","Plasma cells":"93.2","Respiratory ciliated cells":"112.5","T-cells":"89.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"JURKAT":"55.6","Karpas-707":"50.1","SCLC-21H":"53.6","U-266\/70":"58.5","U-266\/84":"76.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"basal ganglia":"37.0"},"Antibody":["HPA005832"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA005832":"AB_1079202"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.47e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.80e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"19.4","Tissue RNA - basal ganglia [nTPM]":"23.9","Tissue RNA - bone marrow [nTPM]":"31.2","Tissue RNA - breast [nTPM]":"6.9","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"7.1","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"9.4","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"3.1","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"12.5","Tissue RNA - fallopian tube [nTPM]":"12.2","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"4.0","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"3.6","Tissue RNA - lung [nTPM]":"9.7","Tissue RNA - lymph node [nTPM]":"33.9","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"6.7","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"9.4","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"10.1","Tissue RNA - seminal vesicle [nTPM]":"3.9","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"7.0","Tissue RNA - small intestine [nTPM]":"11.7","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"21.7","Tissue RNA - stomach 1 [nTPM]":"12.4","Tissue RNA - testis [nTPM]":"8.0","Tissue RNA - thalamus [nTPM]":"7.8","Tissue RNA - thymus [nTPM]":"20.4","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"20.4","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"7.6","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"8.5","Cell RNA - A549 [nTPM]":"6.9","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"34.9","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"6.8","Cell RNA - CAPAN-2 [nTPM]":"13.4","Cell RNA - Daudi [nTPM]":"45.1","Cell RNA - EFO-21 [nTPM]":"6.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"6.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"28.8","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"10.0","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"9.9","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"23.0","Cell RNA - HMC-1 [nTPM]":"8.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"11.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"8.6","Cell RNA - JURKAT [nTPM]":"55.6","Cell RNA - K-562 [nTPM]":"11.2","Cell RNA - Karpas-707 [nTPM]":"50.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"24.9","Cell RNA - MOLT-4 [nTPM]":"24.2","Cell RNA - NB-4 [nTPM]":"29.6","Cell RNA - NTERA-2 [nTPM]":"7.1","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"11.5","Cell RNA - REH [nTPM]":"19.5","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"14.2","Cell RNA - RPTEC TERT1 [nTPM]":"2.6","Cell RNA - RT4 [nTPM]":"10.2","Cell RNA - SCLC-21H [nTPM]":"53.6","Cell RNA - SH-SY5Y [nTPM]":"11.6","Cell RNA - SiHa [nTPM]":"4.6","Cell RNA - SK-BR-3 [nTPM]":"16.9","Cell RNA - SK-MEL-30 [nTPM]":"4.6","Cell RNA - SuSa [nTPM]":"5.6","Cell RNA - T-47d [nTPM]":"10.2","Cell RNA - THP-1 [nTPM]":"20.7","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"58.5","Cell RNA - U-266\/84 [nTPM]":"76.2","Cell RNA - U-698 [nTPM]":"22.8","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"20.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"7.8","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"9.4","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"8.8","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"9.2","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"5.8","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"4.0","Blood RNA - non-classical monocyte [nTPM]":"3.0","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"10.7","Blood RNA - total PBMC [nTPM]":"4.1","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"23.9","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"7.1","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"6.7","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"7.8","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"26.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.8","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"54.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"22.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.6","Single Cell Type RNA - dendritic cells [nTPM]":"80.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"17.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.9","Single Cell Type RNA - Erythroid cells [nTPM]":"20.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"12.4","Single Cell Type RNA - Late spermatids [nTPM]":"18.7","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"18.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"20.1","Single Cell Type RNA - Muller glia cells [nTPM]":"8.0","Single Cell Type RNA - NK-cells [nTPM]":"142.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.8","Single Cell Type RNA - Paneth cells [nTPM]":"18.2","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"93.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"112.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"17.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"89.2","Single Cell Type RNA - Theca cells [nTPM]":"3.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.4","Single Cell Type RNA - Urothelial cells [nTPM]":"19.8"},{"Gene":"CCT5","Gene synonym":["KIAA0098"],"Ensembl":"ENSG00000150753","Gene description":"Chaperonin containing TCP1 subunit 5","Uniprot":["P48643"],"Chromosome":"5","Position":"10249929-10266389","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002238","HPA005958","CAB006271"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB006271":"AB_425898","HPA002238":"AB_1078427","HPA005958":"AB_1846209"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.57e-11"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.23e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"85.3","Tissue RNA - adrenal gland [nTPM]":"79.5","Tissue RNA - amygdala [nTPM]":"68.6","Tissue RNA - appendix [nTPM]":"95.3","Tissue RNA - basal ganglia [nTPM]":"70.4","Tissue RNA - bone marrow [nTPM]":"82.0","Tissue RNA - breast [nTPM]":"74.7","Tissue RNA - cerebellum [nTPM]":"73.2","Tissue RNA - cerebral cortex [nTPM]":"112.4","Tissue RNA - cervix [nTPM]":"58.2","Tissue RNA - choroid plexus [nTPM]":"79.2","Tissue RNA - colon [nTPM]":"85.7","Tissue RNA - duodenum [nTPM]":"67.5","Tissue RNA - endometrium 1 [nTPM]":"66.8","Tissue RNA - epididymis [nTPM]":"53.3","Tissue RNA - esophagus [nTPM]":"100.8","Tissue RNA - fallopian tube [nTPM]":"77.4","Tissue RNA - gallbladder [nTPM]":"48.1","Tissue RNA - heart muscle [nTPM]":"74.8","Tissue RNA - hippocampal formation [nTPM]":"72.7","Tissue RNA - hypothalamus [nTPM]":"82.4","Tissue RNA - kidney [nTPM]":"76.0","Tissue RNA - liver [nTPM]":"74.1","Tissue RNA - lung [nTPM]":"58.7","Tissue RNA - lymph node [nTPM]":"96.3","Tissue RNA - medulla oblongata [nTPM]":"71.5","Tissue RNA - midbrain [nTPM]":"74.7","Tissue RNA - ovary [nTPM]":"50.8","Tissue RNA - pancreas [nTPM]":"58.4","Tissue RNA - parathyroid gland [nTPM]":"175.6","Tissue RNA - pituitary gland [nTPM]":"46.1","Tissue RNA - placenta [nTPM]":"85.8","Tissue RNA - pons [nTPM]":"78.7","Tissue RNA - prostate [nTPM]":"52.3","Tissue RNA - rectum [nTPM]":"97.2","Tissue RNA - retina [nTPM]":"48.9","Tissue RNA - salivary gland [nTPM]":"60.3","Tissue RNA - seminal vesicle [nTPM]":"52.9","Tissue RNA - skeletal muscle [nTPM]":"128.2","Tissue RNA - skin 1 [nTPM]":"60.5","Tissue RNA - small intestine [nTPM]":"62.2","Tissue RNA - smooth muscle [nTPM]":"89.5","Tissue RNA - spinal cord [nTPM]":"74.5","Tissue RNA - spleen [nTPM]":"62.3","Tissue RNA - stomach 1 [nTPM]":"62.6","Tissue RNA - testis [nTPM]":"104.3","Tissue RNA - thalamus [nTPM]":"76.0","Tissue RNA - thymus [nTPM]":"106.6","Tissue RNA - thyroid gland [nTPM]":"63.2","Tissue RNA - tongue [nTPM]":"90.8","Tissue RNA - tonsil [nTPM]":"118.4","Tissue RNA - urinary bladder [nTPM]":"105.8","Tissue RNA - vagina [nTPM]":"63.7","Tissue RNA - white matter [nTPM]":"83.8","Cell RNA - A-431 [nTPM]":"350.5","Cell RNA - A549 [nTPM]":"489.8","Cell RNA - AF22 [nTPM]":"405.1","Cell RNA - AN3-CA [nTPM]":"463.7","Cell RNA - ASC diff [nTPM]":"250.9","Cell RNA - ASC TERT1 [nTPM]":"188.5","Cell RNA - BEWO [nTPM]":"568.4","Cell RNA - BJ [nTPM]":"454.1","Cell RNA - BJ hTERT+ [nTPM]":"288.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"704.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"492.6","Cell RNA - CACO-2 [nTPM]":"657.8","Cell RNA - CAPAN-2 [nTPM]":"372.2","Cell RNA - Daudi [nTPM]":"537.6","Cell RNA - EFO-21 [nTPM]":"490.4","Cell RNA - fHDF\/TERT166 [nTPM]":"326.4","Cell RNA - GAMG [nTPM]":"615.9","Cell RNA - HaCaT [nTPM]":"332.8","Cell RNA - HAP1 [nTPM]":"770.4","Cell RNA - HBEC3-KT [nTPM]":"492.7","Cell RNA - HBF TERT88 [nTPM]":"774.2","Cell RNA - HDLM-2 [nTPM]":"504.5","Cell RNA - HEK 293 [nTPM]":"527.9","Cell RNA - HEL [nTPM]":"440.2","Cell RNA - HeLa [nTPM]":"1063.7","Cell RNA - Hep G2 [nTPM]":"510.7","Cell RNA - HHSteC [nTPM]":"293.8","Cell RNA - HL-60 [nTPM]":"667.6","Cell RNA - HMC-1 [nTPM]":"303.7","Cell RNA - HSkMC [nTPM]":"221.3","Cell RNA - hTCEpi [nTPM]":"300.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"556.8","Cell RNA - hTERT-HME1 [nTPM]":"368.9","Cell RNA - hTERT-RPE1 [nTPM]":"191.4","Cell RNA - HUVEC TERT2 [nTPM]":"422.7","Cell RNA - JURKAT [nTPM]":"343.6","Cell RNA - K-562 [nTPM]":"597.5","Cell RNA - Karpas-707 [nTPM]":"188.2","Cell RNA - LHCN-M2 [nTPM]":"453.3","Cell RNA - MCF7 [nTPM]":"494.0","Cell RNA - MOLT-4 [nTPM]":"481.4","Cell RNA - NB-4 [nTPM]":"659.7","Cell RNA - NTERA-2 [nTPM]":"432.6","Cell RNA - OE19 [nTPM]":"348.3","Cell RNA - PC-3 [nTPM]":"579.4","Cell RNA - REH [nTPM]":"437.9","Cell RNA - RH-30 [nTPM]":"304.4","Cell RNA - RPMI-8226 [nTPM]":"275.8","Cell RNA - RPTEC TERT1 [nTPM]":"447.3","Cell RNA - RT4 [nTPM]":"359.1","Cell RNA - SCLC-21H [nTPM]":"304.8","Cell RNA - SH-SY5Y [nTPM]":"335.3","Cell RNA - SiHa [nTPM]":"953.5","Cell RNA - SK-BR-3 [nTPM]":"424.6","Cell RNA - SK-MEL-30 [nTPM]":"335.6","Cell RNA - SuSa [nTPM]":"316.9","Cell RNA - T-47d [nTPM]":"327.2","Cell RNA - THP-1 [nTPM]":"490.9","Cell RNA - TIME [nTPM]":"285.2","Cell RNA - U-138 MG [nTPM]":"576.4","Cell RNA - U-2 OS [nTPM]":"517.7","Cell RNA - U-2197 [nTPM]":"214.1","Cell RNA - U-251 MG [nTPM]":"687.9","Cell RNA - U-266\/70 [nTPM]":"192.2","Cell RNA - U-266\/84 [nTPM]":"322.7","Cell RNA - U-698 [nTPM]":"570.1","Cell RNA - U-87 MG [nTPM]":"323.7","Cell RNA - U-937 [nTPM]":"955.4","Cell RNA - WM-115 [nTPM]":"470.8","Blood RNA - basophil [nTPM]":"125.6","Blood RNA - classical monocyte [nTPM]":"181.5","Blood RNA - eosinophil [nTPM]":"139.3","Blood RNA - gdT-cell [nTPM]":"117.5","Blood RNA - intermediate monocyte [nTPM]":"248.8","Blood RNA - MAIT T-cell [nTPM]":"155.7","Blood RNA - memory B-cell [nTPM]":"151.6","Blood RNA - memory CD4 T-cell [nTPM]":"131.3","Blood RNA - memory CD8 T-cell [nTPM]":"130.7","Blood RNA - myeloid DC [nTPM]":"188.9","Blood RNA - naive B-cell [nTPM]":"125.6","Blood RNA - naive CD4 T-cell [nTPM]":"121.8","Blood RNA - naive CD8 T-cell [nTPM]":"123.7","Blood RNA - neutrophil [nTPM]":"101.4","Blood RNA - NK-cell [nTPM]":"147.3","Blood RNA - non-classical monocyte [nTPM]":"286.1","Blood RNA - plasmacytoid DC [nTPM]":"69.5","Blood RNA - T-reg [nTPM]":"150.3","Blood RNA - total PBMC [nTPM]":"255.3","Brain RNA - amygdala [nTPM]":"68.6","Brain RNA - basal ganglia [nTPM]":"70.4","Brain RNA - cerebellum [nTPM]":"73.2","Brain RNA - cerebral cortex [nTPM]":"112.4","Brain RNA - hippocampal formation [nTPM]":"72.7","Brain RNA - hypothalamus [nTPM]":"82.4","Brain RNA - medulla oblongata [nTPM]":"71.5","Brain RNA - midbrain [nTPM]":"74.7","Brain RNA - pons [nTPM]":"78.7","Brain RNA - spinal cord [nTPM]":"74.5","Brain RNA - thalamus [nTPM]":"76.0","Brain RNA - white matter [nTPM]":"83.8","Single Cell Type RNA - Adipocytes [nTPM]":"81.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"41.3","Single Cell Type RNA - Astrocytes [nTPM]":"12.1","Single Cell Type RNA - B-cells [nTPM]":"71.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"88.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"172.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"206.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"60.3","Single Cell Type RNA - Bipolar cells [nTPM]":"46.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"50.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"54.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"116.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"214.2","Single Cell Type RNA - dendritic cells [nTPM]":"60.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"81.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"217.4","Single Cell Type RNA - Early spermatids [nTPM]":"235.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"127.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"107.5","Single Cell Type RNA - Endothelial cells [nTPM]":"92.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"70.9","Single Cell Type RNA - Erythroid cells [nTPM]":"98.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"162.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"271.8","Single Cell Type RNA - Fibroblasts [nTPM]":"81.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"62.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"101.1","Single Cell Type RNA - granulocytes [nTPM]":"48.8","Single Cell Type RNA - Granulosa cells [nTPM]":"100.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.0","Single Cell Type RNA - Hepatocytes [nTPM]":"52.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"175.7","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"89.9","Single Cell Type RNA - Ionocytes [nTPM]":"116.0","Single Cell Type RNA - Kupffer cells [nTPM]":"69.2","Single Cell Type RNA - Langerhans cells [nTPM]":"64.7","Single Cell Type RNA - Late spermatids [nTPM]":"93.1","Single Cell Type RNA - Leydig cells [nTPM]":"83.0","Single Cell Type RNA - Macrophages [nTPM]":"84.0","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"92.1","Single Cell Type RNA - Muller glia cells [nTPM]":"56.6","Single Cell Type RNA - NK-cells [nTPM]":"72.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"199.0","Single Cell Type RNA - Paneth cells [nTPM]":"81.8","Single Cell Type RNA - Peritubular cells [nTPM]":"75.6","Single Cell Type RNA - Plasma cells [nTPM]":"59.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"128.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"61.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"99.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"131.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"60.8","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"81.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"272.5","Single Cell Type RNA - Spermatocytes [nTPM]":"282.3","Single Cell Type RNA - Spermatogonia [nTPM]":"184.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"93.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"74.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"155.4","Single Cell Type RNA - T-cells [nTPM]":"66.5","Single Cell Type RNA - Theca cells [nTPM]":"170.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"126.9","Single Cell Type RNA - Urothelial cells [nTPM]":"126.1"},{"Gene":"CD164","Gene synonym":["DFNA66","MGC-24","MUC-24"],"Ensembl":"ENSG00000135535","Gene description":"CD164 molecule","Uniprot":["Q04900"],"Chromosome":"6","Position":"109366514-109382467","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Myogenesis"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010636"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010636":"AB_1078447"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Tissue RNA - adipose tissue [nTPM]":"260.9","Tissue RNA - adrenal gland [nTPM]":"123.6","Tissue RNA - amygdala [nTPM]":"43.6","Tissue RNA - appendix [nTPM]":"119.1","Tissue RNA - basal ganglia [nTPM]":"53.6","Tissue RNA - bone marrow [nTPM]":"213.9","Tissue RNA - breast [nTPM]":"211.2","Tissue RNA - cerebellum [nTPM]":"57.4","Tissue RNA - cerebral cortex [nTPM]":"69.5","Tissue RNA - cervix [nTPM]":"151.0","Tissue RNA - choroid plexus [nTPM]":"68.9","Tissue RNA - colon [nTPM]":"264.8","Tissue RNA - duodenum [nTPM]":"252.0","Tissue RNA - endometrium 1 [nTPM]":"117.0","Tissue RNA - epididymis [nTPM]":"161.9","Tissue RNA - esophagus [nTPM]":"95.0","Tissue RNA - fallopian tube [nTPM]":"124.8","Tissue RNA - gallbladder [nTPM]":"159.3","Tissue RNA - heart muscle [nTPM]":"91.8","Tissue RNA - hippocampal formation [nTPM]":"40.6","Tissue RNA - hypothalamus [nTPM]":"57.7","Tissue RNA - kidney [nTPM]":"298.1","Tissue RNA - liver [nTPM]":"256.8","Tissue RNA - lung [nTPM]":"121.9","Tissue RNA - lymph node [nTPM]":"137.8","Tissue RNA - medulla oblongata [nTPM]":"65.3","Tissue RNA - midbrain [nTPM]":"56.1","Tissue RNA - ovary [nTPM]":"126.4","Tissue RNA - pancreas [nTPM]":"124.1","Tissue RNA - parathyroid gland [nTPM]":"219.2","Tissue RNA - pituitary gland [nTPM]":"89.5","Tissue RNA - placenta [nTPM]":"190.1","Tissue RNA - pons [nTPM]":"64.1","Tissue RNA - prostate [nTPM]":"146.1","Tissue RNA - rectum [nTPM]":"270.5","Tissue RNA - retina [nTPM]":"36.4","Tissue RNA - salivary gland [nTPM]":"303.8","Tissue RNA - seminal vesicle [nTPM]":"112.7","Tissue RNA - skeletal muscle [nTPM]":"96.0","Tissue RNA - skin 1 [nTPM]":"89.2","Tissue RNA - small intestine [nTPM]":"277.6","Tissue RNA - smooth muscle [nTPM]":"116.1","Tissue RNA - spinal cord [nTPM]":"52.3","Tissue RNA - spleen [nTPM]":"121.0","Tissue RNA - stomach 1 [nTPM]":"272.8","Tissue RNA - testis [nTPM]":"113.6","Tissue RNA - thalamus [nTPM]":"50.7","Tissue RNA - thymus [nTPM]":"132.0","Tissue RNA - thyroid gland [nTPM]":"360.4","Tissue RNA - tongue [nTPM]":"91.7","Tissue RNA - tonsil [nTPM]":"122.9","Tissue RNA - urinary bladder [nTPM]":"154.2","Tissue RNA - vagina [nTPM]":"76.0","Tissue RNA - white matter [nTPM]":"70.7","Cell RNA - A-431 [nTPM]":"130.0","Cell RNA - A549 [nTPM]":"73.0","Cell RNA - AF22 [nTPM]":"34.6","Cell RNA - AN3-CA [nTPM]":"242.9","Cell RNA - ASC diff [nTPM]":"503.0","Cell RNA - ASC TERT1 [nTPM]":"496.6","Cell RNA - BEWO [nTPM]":"235.7","Cell RNA - BJ [nTPM]":"230.8","Cell RNA - BJ hTERT+ [nTPM]":"304.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"213.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"308.0","Cell RNA - CACO-2 [nTPM]":"148.1","Cell RNA - CAPAN-2 [nTPM]":"194.9","Cell RNA - Daudi [nTPM]":"105.7","Cell RNA - EFO-21 [nTPM]":"218.0","Cell RNA - fHDF\/TERT166 [nTPM]":"261.5","Cell RNA - GAMG [nTPM]":"198.0","Cell RNA - HaCaT [nTPM]":"125.4","Cell RNA - HAP1 [nTPM]":"136.9","Cell RNA - HBEC3-KT [nTPM]":"152.7","Cell RNA - HBF TERT88 [nTPM]":"315.4","Cell RNA - HDLM-2 [nTPM]":"220.1","Cell RNA - HEK 293 [nTPM]":"144.5","Cell RNA - HEL [nTPM]":"177.8","Cell RNA - HeLa [nTPM]":"72.0","Cell RNA - Hep G2 [nTPM]":"173.9","Cell RNA - HHSteC [nTPM]":"294.9","Cell RNA - HL-60 [nTPM]":"209.5","Cell RNA - HMC-1 [nTPM]":"399.0","Cell RNA - HSkMC [nTPM]":"384.6","Cell RNA - hTCEpi [nTPM]":"279.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"211.3","Cell RNA - hTERT-HME1 [nTPM]":"186.5","Cell RNA - hTERT-RPE1 [nTPM]":"270.3","Cell RNA - HUVEC TERT2 [nTPM]":"196.9","Cell RNA - JURKAT [nTPM]":"86.9","Cell RNA - K-562 [nTPM]":"178.9","Cell RNA - Karpas-707 [nTPM]":"279.9","Cell RNA - LHCN-M2 [nTPM]":"287.8","Cell RNA - MCF7 [nTPM]":"141.1","Cell RNA - MOLT-4 [nTPM]":"191.5","Cell RNA - NB-4 [nTPM]":"251.2","Cell RNA - NTERA-2 [nTPM]":"52.9","Cell RNA - OE19 [nTPM]":"273.1","Cell RNA - PC-3 [nTPM]":"119.6","Cell RNA - REH [nTPM]":"126.3","Cell RNA - RH-30 [nTPM]":"109.0","Cell RNA - RPMI-8226 [nTPM]":"135.1","Cell RNA - RPTEC TERT1 [nTPM]":"292.2","Cell RNA - RT4 [nTPM]":"180.5","Cell RNA - SCLC-21H [nTPM]":"40.2","Cell RNA - SH-SY5Y [nTPM]":"80.9","Cell RNA - SiHa [nTPM]":"144.6","Cell RNA - SK-BR-3 [nTPM]":"184.0","Cell RNA - SK-MEL-30 [nTPM]":"348.6","Cell RNA - SuSa [nTPM]":"168.0","Cell RNA - T-47d [nTPM]":"167.7","Cell RNA - THP-1 [nTPM]":"265.0","Cell RNA - TIME [nTPM]":"205.6","Cell RNA - U-138 MG [nTPM]":"138.8","Cell RNA - U-2 OS [nTPM]":"99.1","Cell RNA - U-2197 [nTPM]":"199.5","Cell RNA - U-251 MG [nTPM]":"188.6","Cell RNA - U-266\/70 [nTPM]":"96.3","Cell RNA - U-266\/84 [nTPM]":"147.4","Cell RNA - U-698 [nTPM]":"121.2","Cell RNA - U-87 MG [nTPM]":"244.0","Cell RNA - U-937 [nTPM]":"242.8","Cell RNA - WM-115 [nTPM]":"147.2","Blood RNA - basophil [nTPM]":"349.0","Blood RNA - classical monocyte [nTPM]":"192.3","Blood RNA - eosinophil [nTPM]":"167.0","Blood RNA - gdT-cell [nTPM]":"166.8","Blood RNA - intermediate monocyte [nTPM]":"198.6","Blood RNA - MAIT T-cell [nTPM]":"175.0","Blood RNA - memory B-cell [nTPM]":"126.2","Blood RNA - memory CD4 T-cell [nTPM]":"135.2","Blood RNA - memory CD8 T-cell [nTPM]":"155.1","Blood RNA - myeloid DC [nTPM]":"189.7","Blood RNA - naive B-cell [nTPM]":"111.0","Blood RNA - naive CD4 T-cell [nTPM]":"138.0","Blood RNA - naive CD8 T-cell [nTPM]":"150.1","Blood RNA - neutrophil [nTPM]":"128.5","Blood RNA - NK-cell [nTPM]":"255.2","Blood RNA - non-classical monocyte [nTPM]":"197.5","Blood RNA - plasmacytoid DC [nTPM]":"214.1","Blood RNA - T-reg [nTPM]":"192.9","Blood RNA - total PBMC [nTPM]":"413.8","Brain RNA - amygdala [nTPM]":"43.6","Brain RNA - basal ganglia [nTPM]":"53.6","Brain RNA - cerebellum [nTPM]":"57.4","Brain RNA - cerebral cortex [nTPM]":"69.5","Brain RNA - hippocampal formation [nTPM]":"40.6","Brain RNA - hypothalamus [nTPM]":"57.7","Brain RNA - medulla oblongata [nTPM]":"65.3","Brain RNA - midbrain [nTPM]":"56.1","Brain RNA - pons [nTPM]":"64.1","Brain RNA - spinal cord [nTPM]":"52.3","Brain RNA - thalamus [nTPM]":"50.7","Brain RNA - white matter [nTPM]":"70.7","Single Cell Type RNA - Adipocytes [nTPM]":"76.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"163.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"78.9","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"168.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"200.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"180.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"149.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"128.7","Single Cell Type RNA - Bipolar cells [nTPM]":"33.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"251.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"123.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"70.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"174.5","Single Cell Type RNA - Club cells [nTPM]":"153.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"281.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"244.9","Single Cell Type RNA - dendritic cells [nTPM]":"372.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"600.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"93.9","Single Cell Type RNA - Ductal cells [nTPM]":"178.8","Single Cell Type RNA - Early spermatids [nTPM]":"103.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"111.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"109.2","Single Cell Type RNA - Endothelial cells [nTPM]":"89.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"166.5","Single Cell Type RNA - Erythroid cells [nTPM]":"92.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"136.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"407.2","Single Cell Type RNA - Fibroblasts [nTPM]":"176.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"175.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"151.2","Single Cell Type RNA - granulocytes [nTPM]":"128.6","Single Cell Type RNA - Granulosa cells [nTPM]":"76.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"98.2","Single Cell Type RNA - Hepatocytes [nTPM]":"177.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"311.9","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"427.3","Single Cell Type RNA - Ionocytes [nTPM]":"215.7","Single Cell Type RNA - Kupffer cells [nTPM]":"360.4","Single Cell Type RNA - Langerhans cells [nTPM]":"223.9","Single Cell Type RNA - Late spermatids [nTPM]":"97.3","Single Cell Type RNA - Leydig cells [nTPM]":"158.8","Single Cell Type RNA - Macrophages [nTPM]":"237.3","Single Cell Type RNA - Melanocytes [nTPM]":"247.3","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"147.1","Single Cell Type RNA - Muller glia cells [nTPM]":"113.3","Single Cell Type RNA - NK-cells [nTPM]":"266.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"83.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"177.6","Single Cell Type RNA - Paneth cells [nTPM]":"430.0","Single Cell Type RNA - Peritubular cells [nTPM]":"182.1","Single Cell Type RNA - Plasma cells [nTPM]":"173.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"230.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"425.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"348.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"351.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.4","Single Cell Type RNA - Sertoli cells [nTPM]":"124.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"110.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"138.1","Single Cell Type RNA - Spermatocytes [nTPM]":"160.5","Single Cell Type RNA - Spermatogonia [nTPM]":"184.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"143.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"231.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"674.5","Single Cell Type RNA - T-cells [nTPM]":"165.9","Single Cell Type RNA - Theca cells [nTPM]":"87.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"285.0","Single Cell Type RNA - Urothelial cells [nTPM]":"334.7"},{"Gene":"CDC14A","Gene synonym":["cdc14","Cdc14A1","Cdc14A2","DFNB105","DFNB32"],"Ensembl":"ENSG00000079335","Gene description":"Cell division cycle 14A","Uniprot":["Q9UNH5"],"Chromosome":"1","Position":"100345001-100520277","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Hearing"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"28.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"145.9","Early spermatids":"171.5","Late spermatids":"191.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"44.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023783"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA023783":"AB_1846352"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.6","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"15.5","Tissue RNA - breast [nTPM]":"11.3","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"5.3","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"13.0","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"6.0","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"3.3","Tissue RNA - prostate [nTPM]":"7.6","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"5.5","Tissue RNA - salivary gland [nTPM]":"3.4","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"10.7","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"28.2","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"4.4","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"3.3","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"8.1","Cell RNA - AN3-CA [nTPM]":"9.3","Cell RNA - ASC diff [nTPM]":"2.9","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"5.7","Cell RNA - BJ [nTPM]":"4.1","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"8.9","Cell RNA - CAPAN-2 [nTPM]":"2.7","Cell RNA - Daudi [nTPM]":"1.6","Cell RNA - EFO-21 [nTPM]":"3.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"3.2","Cell RNA - HaCaT [nTPM]":"2.5","Cell RNA - HAP1 [nTPM]":"5.6","Cell RNA - HBEC3-KT [nTPM]":"2.3","Cell RNA - HBF TERT88 [nTPM]":"4.0","Cell RNA - HDLM-2 [nTPM]":"3.4","Cell RNA - HEK 293 [nTPM]":"13.7","Cell RNA - HEL [nTPM]":"5.8","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"2.9","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"7.8","Cell RNA - HMC-1 [nTPM]":"9.8","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.3","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"2.0","Cell RNA - HUVEC TERT2 [nTPM]":"7.0","Cell RNA - JURKAT [nTPM]":"3.3","Cell RNA - K-562 [nTPM]":"44.7","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"5.8","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"6.3","Cell RNA - NB-4 [nTPM]":"8.7","Cell RNA - NTERA-2 [nTPM]":"5.1","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"3.3","Cell RNA - REH [nTPM]":"6.8","Cell RNA - RH-30 [nTPM]":"10.6","Cell RNA - RPMI-8226 [nTPM]":"1.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"7.2","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"2.7","Cell RNA - SiHa [nTPM]":"4.3","Cell RNA - SK-BR-3 [nTPM]":"4.1","Cell RNA - SK-MEL-30 [nTPM]":"5.6","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"10.0","Cell RNA - TIME [nTPM]":"3.1","Cell RNA - U-138 MG [nTPM]":"2.2","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"2.4","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"2.5","Cell RNA - U-87 MG [nTPM]":"2.7","Cell RNA - U-937 [nTPM]":"7.3","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"12.2","Blood RNA - classical monocyte [nTPM]":"3.6","Blood RNA - eosinophil [nTPM]":"9.0","Blood RNA - gdT-cell [nTPM]":"6.9","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"12.5","Blood RNA - memory B-cell [nTPM]":"4.5","Blood RNA - memory CD4 T-cell [nTPM]":"10.9","Blood RNA - memory CD8 T-cell [nTPM]":"8.2","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"10.2","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"5.4","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"4.1","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"3.3","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"14.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"145.9","Single Cell Type RNA - B-cells [nTPM]":"10.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - dendritic cells [nTPM]":"23.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"171.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.8","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"51.1","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"4.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.3","Single Cell Type RNA - Late spermatids [nTPM]":"191.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"11.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"9.3","Single Cell Type RNA - Muller glia cells [nTPM]":"11.4","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"53.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"11.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"13.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"44.1","Single Cell Type RNA - Theca cells [nTPM]":"3.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"CDH23","Gene synonym":["CDHR23","DFNB12","USH1D"],"Ensembl":"ENSG00000107736","Gene description":"Cadherin related 23","Uniprot":["Q9H251"],"Chromosome":"10","Position":"71396920-71815947","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Hearing","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.6","ovary":"35.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"78.4","Late spermatids":"67.7","Microglial cells":"33.7","Muller glia cells":"90.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"26.8","non-classical monocyte":"38.1","plasmacytoid DC":"9.5"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"monocytes":"38.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"RT4":"13.4","SCLC-21H":"5.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017232"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"950000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017232":"AB_1845903"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.40e-4"},"Tissue RNA - adipose tissue [nTPM]":"11.3","Tissue RNA - adrenal gland [nTPM]":"3.3","Tissue RNA - amygdala [nTPM]":"9.6","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"10.6","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"3.3","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"1.7","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"1.8","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"16.2","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"14.4","Tissue RNA - lung [nTPM]":"7.8","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"35.6","Tissue RNA - midbrain [nTPM]":"18.5","Tissue RNA - ovary [nTPM]":"35.3","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"9.9","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"34.7","Tissue RNA - prostate [nTPM]":"3.7","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"14.4","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"2.3","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"11.0","Tissue RNA - thalamus [nTPM]":"23.6","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"1.8","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"8.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"1.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"1.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"5.3","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"2.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"1.5","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"6.0","Blood RNA - eosinophil [nTPM]":"5.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"26.8","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"4.9","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"6.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"38.1","Blood RNA - plasmacytoid DC [nTPM]":"9.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"9.6","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"10.6","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"16.2","Brain RNA - medulla oblongata [nTPM]":"35.6","Brain RNA - midbrain [nTPM]":"18.5","Brain RNA - pons [nTPM]":"34.7","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"23.6","Brain RNA - white matter [nTPM]":"8.8","Single Cell Type RNA - Adipocytes [nTPM]":"8.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"78.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"20.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.2","Single Cell Type RNA - Langerhans cells [nTPM]":"11.6","Single Cell Type RNA - Late spermatids [nTPM]":"67.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"15.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"10.6","Single Cell Type RNA - Muller glia cells [nTPM]":"90.7","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"CDHR1","Gene synonym":["CORD15","KIAA1775","PCDH21","RP65"],"Ensembl":"ENSG00000148600","Gene description":"Cadherin related family member 1","Uniprot":["Q96JP9"],"Chromosome":"10","Position":"84194537-84219621","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Receptor"],"Disease involvement":["Cone-rod dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"313.8","skin 1":"214.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"379.5","Rod photoreceptor cells":"240.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"13.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"NK-cell":"7.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"NK-cells":"7.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"10.2","HEK 293":"5.2","HEL":"6.3","K-562":"4.6","NTERA-2":"4.4","RPTEC TERT1":"16.3"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"21","RNA mouse brain regional specific nTPM":{"olfactory bulb":"333.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036819"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036819":"AB_10671750"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"18.3","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"4.5","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"8.7","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"46.2","Tissue RNA - colon [nTPM]":"29.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"7.5","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"13.4","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"13.9","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"53.2","Tissue RNA - retina [nTPM]":"313.8","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"214.0","Tissue RNA - small intestine [nTPM]":"12.2","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"10.2","Cell RNA - HBEC3-KT [nTPM]":"2.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"6.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"4.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.5","Cell RNA - NTERA-2 [nTPM]":"4.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"16.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"7.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"18.3","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"8.7","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"7.5","Brain RNA - medulla oblongata [nTPM]":"13.4","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"13.9","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"51.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"24.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"379.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"47.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"26.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"31.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"240.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"67.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CDK19","Gene synonym":["bA346C16.3","CDC2L6","CDK11","KIAA1028"],"Ensembl":"ENSG00000155111","Gene description":"Cyclin dependent kinase 19","Uniprot":["Q9BWU1"],"Chromosome":"6","Position":"110609978-110815958","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"40.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"137.1","Oligodendrocyte precursor cells":"154.8","Oligodendrocytes":"476.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"23.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"4.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007053","HPA007062"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA007053":"AB_1233803","HPA007062":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.56e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.72e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"3.4","Tissue RNA - amygdala [nTPM]":"22.7","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"32.1","Tissue RNA - bone marrow [nTPM]":"11.7","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"17.9","Tissue RNA - cerebral cortex [nTPM]":"29.0","Tissue RNA - cervix [nTPM]":"6.6","Tissue RNA - choroid plexus [nTPM]":"7.5","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"3.8","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"4.4","Tissue RNA - hippocampal formation [nTPM]":"20.8","Tissue RNA - hypothalamus [nTPM]":"19.3","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"5.0","Tissue RNA - lung [nTPM]":"6.7","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"28.8","Tissue RNA - midbrain [nTPM]":"24.7","Tissue RNA - ovary [nTPM]":"9.8","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"11.5","Tissue RNA - pons [nTPM]":"22.7","Tissue RNA - prostate [nTPM]":"26.7","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"8.8","Tissue RNA - salivary gland [nTPM]":"4.4","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"8.5","Tissue RNA - small intestine [nTPM]":"6.7","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"19.4","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"7.1","Tissue RNA - testis [nTPM]":"18.5","Tissue RNA - thalamus [nTPM]":"26.9","Tissue RNA - thymus [nTPM]":"13.6","Tissue RNA - thyroid gland [nTPM]":"6.1","Tissue RNA - tongue [nTPM]":"5.4","Tissue RNA - tonsil [nTPM]":"9.2","Tissue RNA - urinary bladder [nTPM]":"5.3","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"40.8","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"6.1","Cell RNA - AF22 [nTPM]":"21.8","Cell RNA - AN3-CA [nTPM]":"26.4","Cell RNA - ASC diff [nTPM]":"11.1","Cell RNA - ASC TERT1 [nTPM]":"15.6","Cell RNA - BEWO [nTPM]":"10.8","Cell RNA - BJ [nTPM]":"18.8","Cell RNA - BJ hTERT+ [nTPM]":"19.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.8","Cell RNA - CACO-2 [nTPM]":"7.6","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"14.7","Cell RNA - EFO-21 [nTPM]":"6.5","Cell RNA - fHDF\/TERT166 [nTPM]":"13.2","Cell RNA - GAMG [nTPM]":"13.9","Cell RNA - HaCaT [nTPM]":"3.2","Cell RNA - HAP1 [nTPM]":"8.0","Cell RNA - HBEC3-KT [nTPM]":"3.9","Cell RNA - HBF TERT88 [nTPM]":"15.4","Cell RNA - HDLM-2 [nTPM]":"18.2","Cell RNA - HEK 293 [nTPM]":"4.5","Cell RNA - HEL [nTPM]":"26.0","Cell RNA - HeLa [nTPM]":"8.8","Cell RNA - Hep G2 [nTPM]":"8.9","Cell RNA - HHSteC [nTPM]":"6.8","Cell RNA - HL-60 [nTPM]":"10.5","Cell RNA - HMC-1 [nTPM]":"18.2","Cell RNA - HSkMC [nTPM]":"10.7","Cell RNA - hTCEpi [nTPM]":"8.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.7","Cell RNA - hTERT-HME1 [nTPM]":"14.1","Cell RNA - hTERT-RPE1 [nTPM]":"17.0","Cell RNA - HUVEC TERT2 [nTPM]":"6.8","Cell RNA - JURKAT [nTPM]":"12.3","Cell RNA - K-562 [nTPM]":"7.6","Cell RNA - Karpas-707 [nTPM]":"20.2","Cell RNA - LHCN-M2 [nTPM]":"14.5","Cell RNA - MCF7 [nTPM]":"9.7","Cell RNA - MOLT-4 [nTPM]":"14.3","Cell RNA - NB-4 [nTPM]":"15.0","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"8.1","Cell RNA - PC-3 [nTPM]":"4.1","Cell RNA - REH [nTPM]":"14.8","Cell RNA - RH-30 [nTPM]":"11.3","Cell RNA - RPMI-8226 [nTPM]":"5.8","Cell RNA - RPTEC TERT1 [nTPM]":"7.8","Cell RNA - RT4 [nTPM]":"11.0","Cell RNA - SCLC-21H [nTPM]":"10.6","Cell RNA - SH-SY5Y [nTPM]":"19.8","Cell RNA - SiHa [nTPM]":"14.4","Cell RNA - SK-BR-3 [nTPM]":"11.3","Cell RNA - SK-MEL-30 [nTPM]":"17.0","Cell RNA - SuSa [nTPM]":"7.2","Cell RNA - T-47d [nTPM]":"3.9","Cell RNA - THP-1 [nTPM]":"37.1","Cell RNA - TIME [nTPM]":"7.7","Cell RNA - U-138 MG [nTPM]":"14.2","Cell RNA - U-2 OS [nTPM]":"7.6","Cell RNA - U-2197 [nTPM]":"29.6","Cell RNA - U-251 MG [nTPM]":"11.4","Cell RNA - U-266\/70 [nTPM]":"2.1","Cell RNA - U-266\/84 [nTPM]":"3.2","Cell RNA - U-698 [nTPM]":"12.8","Cell RNA - U-87 MG [nTPM]":"15.6","Cell RNA - U-937 [nTPM]":"13.7","Cell RNA - WM-115 [nTPM]":"14.9","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"4.6","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"22.7","Brain RNA - basal ganglia [nTPM]":"32.1","Brain RNA - cerebellum [nTPM]":"17.9","Brain RNA - cerebral cortex [nTPM]":"29.0","Brain RNA - hippocampal formation [nTPM]":"20.8","Brain RNA - hypothalamus [nTPM]":"19.3","Brain RNA - medulla oblongata [nTPM]":"28.8","Brain RNA - midbrain [nTPM]":"24.7","Brain RNA - pons [nTPM]":"22.7","Brain RNA - spinal cord [nTPM]":"19.4","Brain RNA - thalamus [nTPM]":"26.9","Brain RNA - white matter [nTPM]":"40.8","Single Cell Type RNA - Adipocytes [nTPM]":"15.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.8","Single Cell Type RNA - Astrocytes [nTPM]":"50.6","Single Cell Type RNA - B-cells [nTPM]":"19.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"19.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - dendritic cells [nTPM]":"17.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.5","Single Cell Type RNA - Early spermatids [nTPM]":"102.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.5","Single Cell Type RNA - Endothelial cells [nTPM]":"13.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.6","Single Cell Type RNA - Erythroid cells [nTPM]":"21.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"85.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.4","Single Cell Type RNA - Fibroblasts [nTPM]":"12.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.6","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"23.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"12.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.4","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"51.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.5","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"33.9","Single Cell Type RNA - Langerhans cells [nTPM]":"19.9","Single Cell Type RNA - Late spermatids [nTPM]":"137.1","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"22.1","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"62.8","Single Cell Type RNA - monocytes [nTPM]":"19.6","Single Cell Type RNA - Muller glia cells [nTPM]":"33.9","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"154.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"476.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.0","Single Cell Type RNA - Paneth cells [nTPM]":"20.0","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"5.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.3","Single Cell Type RNA - Spermatocytes [nTPM]":"56.6","Single Cell Type RNA - Spermatogonia [nTPM]":"15.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.9","Single Cell Type RNA - T-cells [nTPM]":"13.3","Single Cell Type RNA - Theca cells [nTPM]":"10.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.8","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"},{"Gene":"CDKL5","Gene synonym":["CFAP247","EIEE2","STK9"],"Ensembl":"ENSG00000008086","Gene description":"Cyclin dependent kinase like 5","Uniprot":["O76039"],"Chromosome":"X","Position":"18425583-18653629","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"216.6","Horizontal cells":"80.8","Inhibitory neurons":"116.1","Oligodendrocytes":"79.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"5.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"5.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"10.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002847","CAB011577"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB011577":"AB_727019","HPA002847":"AB_1080107"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.54e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"2.5","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"11.7","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"2.6","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"2.4","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"12.2","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"7.1","Tissue RNA - thalamus [nTPM]":"5.7","Tissue RNA - thymus [nTPM]":"1.7","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"10.0","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"2.2","Cell RNA - ASC diff [nTPM]":"2.4","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"1.7","Cell RNA - BJ hTERT+ [nTPM]":"3.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.5","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"3.2","Cell RNA - HBEC3-KT [nTPM]":"1.8","Cell RNA - HBF TERT88 [nTPM]":"4.3","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"5.5","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"4.9","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"2.7","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"3.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.8","Cell RNA - RT4 [nTPM]":"7.1","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"3.2","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"1.5","Cell RNA - SuSa [nTPM]":"4.4","Cell RNA - T-47d [nTPM]":"1.3","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"6.2","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"5.5","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"1.4","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"5.7","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"11.7","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"5.7","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"9.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.8","Single Cell Type RNA - Astrocytes [nTPM]":"37.5","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"19.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"5.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.4","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.7","Single Cell Type RNA - Early spermatids [nTPM]":"34.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"216.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.1","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.2","Single Cell Type RNA - Horizontal cells [nTPM]":"80.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"116.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"55.3","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"4.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"4.6","Single Cell Type RNA - Muller glia cells [nTPM]":"23.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"79.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"4.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.4","Single Cell Type RNA - Spermatocytes [nTPM]":"5.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"47.3","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.8","Single Cell Type RNA - Urothelial cells [nTPM]":"22.9"},{"Gene":"CEACAM16","Gene synonym":["DFNA4B"],"Ensembl":"ENSG00000213892","Gene description":"CEA cell adhesion molecule 16, tectorial membrane component","Uniprot":["Q2WEN9"],"Chromosome":"19","Position":"44699151-44710718","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"2.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"7.7","Skeletal myocytes":"20.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"1.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045075"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045075":"AB_10959617"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.5","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"7.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CEP250","Gene synonym":["C-NAP1","CEP2"],"Ensembl":"ENSG00000126001","Gene description":"Centrosomal protein 250","Uniprot":["Q9BV73"],"Chromosome":"20","Position":"35455164-35519280","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064875"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA064875":"AB_2685379"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.77e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.27e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.97e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.2","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"12.8","Tissue RNA - appendix [nTPM]":"13.5","Tissue RNA - basal ganglia [nTPM]":"12.8","Tissue RNA - bone marrow [nTPM]":"22.6","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"11.9","Tissue RNA - cervix [nTPM]":"11.3","Tissue RNA - choroid plexus [nTPM]":"11.3","Tissue RNA - colon [nTPM]":"10.6","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"8.9","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"7.5","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"11.6","Tissue RNA - hypothalamus [nTPM]":"13.4","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"6.7","Tissue RNA - lung [nTPM]":"7.1","Tissue RNA - lymph node [nTPM]":"23.3","Tissue RNA - medulla oblongata [nTPM]":"11.6","Tissue RNA - midbrain [nTPM]":"12.5","Tissue RNA - ovary [nTPM]":"14.2","Tissue RNA - pancreas [nTPM]":"7.3","Tissue RNA - parathyroid gland [nTPM]":"12.7","Tissue RNA - pituitary gland [nTPM]":"12.2","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"11.1","Tissue RNA - prostate [nTPM]":"12.2","Tissue RNA - rectum [nTPM]":"8.3","Tissue RNA - retina [nTPM]":"15.7","Tissue RNA - salivary gland [nTPM]":"10.1","Tissue RNA - seminal vesicle [nTPM]":"8.7","Tissue RNA - skeletal muscle [nTPM]":"9.4","Tissue RNA - skin 1 [nTPM]":"13.3","Tissue RNA - small intestine [nTPM]":"11.2","Tissue RNA - smooth muscle [nTPM]":"9.7","Tissue RNA - spinal cord [nTPM]":"9.8","Tissue RNA - spleen [nTPM]":"20.2","Tissue RNA - stomach 1 [nTPM]":"8.3","Tissue RNA - testis [nTPM]":"18.8","Tissue RNA - thalamus [nTPM]":"14.9","Tissue RNA - thymus [nTPM]":"16.3","Tissue RNA - thyroid gland [nTPM]":"8.7","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"14.3","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"11.6","Cell RNA - A-431 [nTPM]":"33.9","Cell RNA - A549 [nTPM]":"38.2","Cell RNA - AF22 [nTPM]":"18.5","Cell RNA - AN3-CA [nTPM]":"34.6","Cell RNA - ASC diff [nTPM]":"27.6","Cell RNA - ASC TERT1 [nTPM]":"24.8","Cell RNA - BEWO [nTPM]":"27.4","Cell RNA - BJ [nTPM]":"16.5","Cell RNA - BJ hTERT+ [nTPM]":"18.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.3","Cell RNA - CACO-2 [nTPM]":"51.2","Cell RNA - CAPAN-2 [nTPM]":"27.0","Cell RNA - Daudi [nTPM]":"36.4","Cell RNA - EFO-21 [nTPM]":"21.5","Cell RNA - fHDF\/TERT166 [nTPM]":"23.7","Cell RNA - GAMG [nTPM]":"80.4","Cell RNA - HaCaT [nTPM]":"36.6","Cell RNA - HAP1 [nTPM]":"20.0","Cell RNA - HBEC3-KT [nTPM]":"50.7","Cell RNA - HBF TERT88 [nTPM]":"28.7","Cell RNA - HDLM-2 [nTPM]":"6.9","Cell RNA - HEK 293 [nTPM]":"8.2","Cell RNA - HEL [nTPM]":"68.1","Cell RNA - HeLa [nTPM]":"31.0","Cell RNA - Hep G2 [nTPM]":"49.0","Cell RNA - HHSteC [nTPM]":"16.7","Cell RNA - HL-60 [nTPM]":"33.7","Cell RNA - HMC-1 [nTPM]":"36.6","Cell RNA - HSkMC [nTPM]":"17.7","Cell RNA - hTCEpi [nTPM]":"30.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.7","Cell RNA - hTERT-HME1 [nTPM]":"61.9","Cell RNA - hTERT-RPE1 [nTPM]":"29.3","Cell RNA - HUVEC TERT2 [nTPM]":"27.0","Cell RNA - JURKAT [nTPM]":"38.3","Cell RNA - K-562 [nTPM]":"23.7","Cell RNA - Karpas-707 [nTPM]":"33.8","Cell RNA - LHCN-M2 [nTPM]":"44.2","Cell RNA - MCF7 [nTPM]":"17.4","Cell RNA - MOLT-4 [nTPM]":"41.5","Cell RNA - NB-4 [nTPM]":"34.0","Cell RNA - NTERA-2 [nTPM]":"12.4","Cell RNA - OE19 [nTPM]":"18.0","Cell RNA - PC-3 [nTPM]":"43.1","Cell RNA - REH [nTPM]":"23.6","Cell RNA - RH-30 [nTPM]":"53.6","Cell RNA - RPMI-8226 [nTPM]":"10.1","Cell RNA - RPTEC TERT1 [nTPM]":"24.7","Cell RNA - RT4 [nTPM]":"38.4","Cell RNA - SCLC-21H [nTPM]":"24.9","Cell RNA - SH-SY5Y [nTPM]":"27.7","Cell RNA - SiHa [nTPM]":"45.6","Cell RNA - SK-BR-3 [nTPM]":"30.3","Cell RNA - SK-MEL-30 [nTPM]":"21.5","Cell RNA - SuSa [nTPM]":"14.9","Cell RNA - T-47d [nTPM]":"21.3","Cell RNA - THP-1 [nTPM]":"29.3","Cell RNA - TIME [nTPM]":"43.7","Cell RNA - U-138 MG [nTPM]":"113.5","Cell RNA - U-2 OS [nTPM]":"29.3","Cell RNA - U-2197 [nTPM]":"42.4","Cell RNA - U-251 MG [nTPM]":"23.8","Cell RNA - U-266\/70 [nTPM]":"11.7","Cell RNA - U-266\/84 [nTPM]":"13.6","Cell RNA - U-698 [nTPM]":"33.9","Cell RNA - U-87 MG [nTPM]":"63.1","Cell RNA - U-937 [nTPM]":"22.4","Cell RNA - WM-115 [nTPM]":"19.9","Blood RNA - basophil [nTPM]":"20.2","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"5.2","Blood RNA - gdT-cell [nTPM]":"10.5","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"6.5","Blood RNA - memory B-cell [nTPM]":"5.7","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"8.5","Blood RNA - myeloid DC [nTPM]":"4.1","Blood RNA - naive B-cell [nTPM]":"6.7","Blood RNA - naive CD4 T-cell [nTPM]":"5.3","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"14.1","Blood RNA - T-reg [nTPM]":"5.1","Blood RNA - total PBMC [nTPM]":"4.6","Brain RNA - amygdala [nTPM]":"12.8","Brain RNA - basal ganglia [nTPM]":"12.8","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"11.9","Brain RNA - hippocampal formation [nTPM]":"11.6","Brain RNA - hypothalamus [nTPM]":"13.4","Brain RNA - medulla oblongata [nTPM]":"11.6","Brain RNA - midbrain [nTPM]":"12.5","Brain RNA - pons [nTPM]":"11.1","Brain RNA - spinal cord [nTPM]":"9.8","Brain RNA - thalamus [nTPM]":"14.9","Brain RNA - white matter [nTPM]":"11.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.2","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"14.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"21.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"12.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.6","Single Cell Type RNA - dendritic cells [nTPM]":"15.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"11.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"11.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"20.0","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"4.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"24.1","Single Cell Type RNA - Spermatogonia [nTPM]":"14.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"5.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"CEP290","Gene synonym":["3H11Ag","BBS14","CT87","FLJ13615","JBTS5","KIAA0373","LCA10","MKS4","NPHP6","POC3","rd16","SLSN6"],"Ensembl":"ENSG00000198707","Gene description":"Centrosomal protein 290","Uniprot":["O15078"],"Chromosome":"12","Position":"88049016-88142099","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Protein transport","Transport"],"Molecular function":["Activator"],"Disease involvement":["Bardet-Biedl syndrome","Ciliopathy","Disease variant","Joubert syndrome","Leber congenital amaurosis","Meckel syndrome","Mental retardation","Nephronophthisis","Obesity","Senior-Loken syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"150.5","Spermatocytes":"143.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB029995","HPA043918","HPA064397"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"CAB029995":null,"HPA043918":"AB_2678730","HPA064397":"AB_2685255"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"2.8","Tissue RNA - breast [nTPM]":"5.0","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"6.3","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"4.5","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"3.6","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"2.1","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"4.6","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"4.5","Tissue RNA - stomach 1 [nTPM]":"4.8","Tissue RNA - testis [nTPM]":"8.6","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"4.3","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"6.0","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"8.3","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"9.8","Cell RNA - AN3-CA [nTPM]":"2.0","Cell RNA - ASC diff [nTPM]":"4.2","Cell RNA - ASC TERT1 [nTPM]":"16.1","Cell RNA - BEWO [nTPM]":"3.8","Cell RNA - BJ [nTPM]":"8.2","Cell RNA - BJ hTERT+ [nTPM]":"6.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"7.3","Cell RNA - CAPAN-2 [nTPM]":"3.3","Cell RNA - Daudi [nTPM]":"7.6","Cell RNA - EFO-21 [nTPM]":"3.6","Cell RNA - fHDF\/TERT166 [nTPM]":"6.1","Cell RNA - GAMG [nTPM]":"9.1","Cell RNA - HaCaT [nTPM]":"6.4","Cell RNA - HAP1 [nTPM]":"2.7","Cell RNA - HBEC3-KT [nTPM]":"5.2","Cell RNA - HBF TERT88 [nTPM]":"9.1","Cell RNA - HDLM-2 [nTPM]":"4.2","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"7.5","Cell RNA - HeLa [nTPM]":"4.5","Cell RNA - Hep G2 [nTPM]":"4.7","Cell RNA - HHSteC [nTPM]":"7.6","Cell RNA - HL-60 [nTPM]":"10.0","Cell RNA - HMC-1 [nTPM]":"3.4","Cell RNA - HSkMC [nTPM]":"8.3","Cell RNA - hTCEpi [nTPM]":"3.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.5","Cell RNA - hTERT-HME1 [nTPM]":"10.4","Cell RNA - hTERT-RPE1 [nTPM]":"11.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.3","Cell RNA - JURKAT [nTPM]":"6.5","Cell RNA - K-562 [nTPM]":"15.4","Cell RNA - Karpas-707 [nTPM]":"1.4","Cell RNA - LHCN-M2 [nTPM]":"11.0","Cell RNA - MCF7 [nTPM]":"3.8","Cell RNA - MOLT-4 [nTPM]":"5.7","Cell RNA - NB-4 [nTPM]":"6.2","Cell RNA - NTERA-2 [nTPM]":"2.5","Cell RNA - OE19 [nTPM]":"1.3","Cell RNA - PC-3 [nTPM]":"8.5","Cell RNA - REH [nTPM]":"4.5","Cell RNA - RH-30 [nTPM]":"11.6","Cell RNA - RPMI-8226 [nTPM]":"5.1","Cell RNA - RPTEC TERT1 [nTPM]":"4.9","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"8.3","Cell RNA - SiHa [nTPM]":"5.0","Cell RNA - SK-BR-3 [nTPM]":"2.5","Cell RNA - SK-MEL-30 [nTPM]":"6.4","Cell RNA - SuSa [nTPM]":"7.6","Cell RNA - T-47d [nTPM]":"11.3","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"10.0","Cell RNA - U-138 MG [nTPM]":"9.5","Cell RNA - U-2 OS [nTPM]":"5.5","Cell RNA - U-2197 [nTPM]":"8.1","Cell RNA - U-251 MG [nTPM]":"10.7","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"10.4","Cell RNA - U-698 [nTPM]":"8.2","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"3.7","Cell RNA - WM-115 [nTPM]":"3.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"29.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.1","Single Cell Type RNA - Astrocytes [nTPM]":"56.2","Single Cell Type RNA - B-cells [nTPM]":"22.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"65.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"50.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"35.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"102.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.0","Single Cell Type RNA - dendritic cells [nTPM]":"28.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"26.0","Single Cell Type RNA - Early spermatids [nTPM]":"70.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"89.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"57.0","Single Cell Type RNA - Endothelial cells [nTPM]":"24.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"91.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.8","Single Cell Type RNA - Fibroblasts [nTPM]":"26.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.1","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"56.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"5.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.9","Single Cell Type RNA - Horizontal cells [nTPM]":"65.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"93.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.4","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"29.4","Single Cell Type RNA - Leydig cells [nTPM]":"28.6","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"11.4","Single Cell Type RNA - Muller glia cells [nTPM]":"35.0","Single Cell Type RNA - NK-cells [nTPM]":"33.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"67.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"100.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.0","Single Cell Type RNA - Paneth cells [nTPM]":"6.5","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"22.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"81.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"150.5","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.2","Single Cell Type RNA - Spermatocytes [nTPM]":"143.9","Single Cell Type RNA - Spermatogonia [nTPM]":"53.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"23.7","Single Cell Type RNA - Theca cells [nTPM]":"46.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.8","Single Cell Type RNA - Urothelial cells [nTPM]":"9.4"},{"Gene":"CEP78","Gene synonym":["C9orf81","FLJ12643"],"Ensembl":"ENSG00000148019","Gene description":"Centrosomal protein 78","Uniprot":["Q5JTW2"],"Chromosome":"9","Position":"78236062-78279690","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Cone-rod dystrophy","Deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"110.5","dendritic cells":"106.8","NK-cells":"249.3","Spermatocytes":"82.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"39.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"NK-cells":"39.1","T-cells":"18.3"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048846"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048846":"AB_2680537"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.2","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"12.3","Tissue RNA - breast [nTPM]":"4.3","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"4.1","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"3.5","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"3.4","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"3.5","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"6.2","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"3.1","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"9.2","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"3.5","Tissue RNA - small intestine [nTPM]":"2.9","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"5.1","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"3.0","Tissue RNA - testis [nTPM]":"15.1","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"11.5","Tissue RNA - thyroid gland [nTPM]":"3.7","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"3.2","Tissue RNA - vagina [nTPM]":"3.0","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"31.7","Cell RNA - A549 [nTPM]":"14.5","Cell RNA - AF22 [nTPM]":"33.3","Cell RNA - AN3-CA [nTPM]":"20.5","Cell RNA - ASC diff [nTPM]":"5.4","Cell RNA - ASC TERT1 [nTPM]":"9.4","Cell RNA - BEWO [nTPM]":"22.3","Cell RNA - BJ [nTPM]":"25.6","Cell RNA - BJ hTERT+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.1","Cell RNA - CACO-2 [nTPM]":"2.7","Cell RNA - CAPAN-2 [nTPM]":"8.4","Cell RNA - Daudi [nTPM]":"28.9","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"9.2","Cell RNA - GAMG [nTPM]":"21.4","Cell RNA - HaCaT [nTPM]":"36.9","Cell RNA - HAP1 [nTPM]":"49.6","Cell RNA - HBEC3-KT [nTPM]":"13.7","Cell RNA - HBF TERT88 [nTPM]":"22.5","Cell RNA - HDLM-2 [nTPM]":"24.3","Cell RNA - HEK 293 [nTPM]":"16.6","Cell RNA - HEL [nTPM]":"15.4","Cell RNA - HeLa [nTPM]":"17.1","Cell RNA - Hep G2 [nTPM]":"11.4","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"26.0","Cell RNA - HMC-1 [nTPM]":"14.6","Cell RNA - HSkMC [nTPM]":"5.2","Cell RNA - hTCEpi [nTPM]":"2.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.1","Cell RNA - hTERT-HME1 [nTPM]":"11.1","Cell RNA - hTERT-RPE1 [nTPM]":"7.5","Cell RNA - HUVEC TERT2 [nTPM]":"23.4","Cell RNA - JURKAT [nTPM]":"29.4","Cell RNA - K-562 [nTPM]":"12.2","Cell RNA - Karpas-707 [nTPM]":"22.4","Cell RNA - LHCN-M2 [nTPM]":"19.8","Cell RNA - MCF7 [nTPM]":"20.3","Cell RNA - MOLT-4 [nTPM]":"32.6","Cell RNA - NB-4 [nTPM]":"12.8","Cell RNA - NTERA-2 [nTPM]":"35.2","Cell RNA - OE19 [nTPM]":"32.7","Cell RNA - PC-3 [nTPM]":"14.0","Cell RNA - REH [nTPM]":"32.2","Cell RNA - RH-30 [nTPM]":"38.4","Cell RNA - RPMI-8226 [nTPM]":"8.4","Cell RNA - RPTEC TERT1 [nTPM]":"9.0","Cell RNA - RT4 [nTPM]":"14.0","Cell RNA - SCLC-21H [nTPM]":"30.4","Cell RNA - SH-SY5Y [nTPM]":"21.1","Cell RNA - SiHa [nTPM]":"33.7","Cell RNA - SK-BR-3 [nTPM]":"10.6","Cell RNA - SK-MEL-30 [nTPM]":"8.4","Cell RNA - SuSa [nTPM]":"22.7","Cell RNA - T-47d [nTPM]":"12.6","Cell RNA - THP-1 [nTPM]":"6.9","Cell RNA - TIME [nTPM]":"12.5","Cell RNA - U-138 MG [nTPM]":"13.3","Cell RNA - U-2 OS [nTPM]":"22.6","Cell RNA - U-2197 [nTPM]":"27.5","Cell RNA - U-251 MG [nTPM]":"24.7","Cell RNA - U-266\/70 [nTPM]":"13.1","Cell RNA - U-266\/84 [nTPM]":"17.8","Cell RNA - U-698 [nTPM]":"18.4","Cell RNA - U-87 MG [nTPM]":"11.8","Cell RNA - U-937 [nTPM]":"17.6","Cell RNA - WM-115 [nTPM]":"23.0","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"18.3","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"8.9","Blood RNA - memory B-cell [nTPM]":"5.0","Blood RNA - memory CD4 T-cell [nTPM]":"7.9","Blood RNA - memory CD8 T-cell [nTPM]":"16.0","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.9","Blood RNA - naive CD8 T-cell [nTPM]":"12.8","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"39.1","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"4.2","Blood RNA - T-reg [nTPM]":"13.1","Blood RNA - total PBMC [nTPM]":"8.3","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"5.1","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"10.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"13.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"27.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"110.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - dendritic cells [nTPM]":"106.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.4","Single Cell Type RNA - Early spermatids [nTPM]":"14.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.9","Single Cell Type RNA - Endothelial cells [nTPM]":"9.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"25.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.5","Single Cell Type RNA - Fibroblasts [nTPM]":"10.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.4","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"20.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"9.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.6","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.1","Single Cell Type RNA - Langerhans cells [nTPM]":"6.1","Single Cell Type RNA - Late spermatids [nTPM]":"9.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"10.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"9.7","Single Cell Type RNA - Muller glia cells [nTPM]":"14.7","Single Cell Type RNA - NK-cells [nTPM]":"249.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.1","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"43.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.3","Single Cell Type RNA - Spermatocytes [nTPM]":"82.1","Single Cell Type RNA - Spermatogonia [nTPM]":"34.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"34.0","Single Cell Type RNA - Theca cells [nTPM]":"12.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.2","Single Cell Type RNA - Urothelial cells [nTPM]":"4.0"},{"Gene":"CERKL","Gene synonym":["RP26"],"Ensembl":"ENSG00000188452","Gene description":"Ceramide kinase like","Uniprot":["Q49MI3"],"Chromosome":"2","Position":"181536672-181680665","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"17.1","retina":"16.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"18.8","Endometrial ciliated cells":"43.5","Proximal tubular cells":"13.4","Respiratory ciliated cells":"38.7","Rod photoreceptor cells":"22.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"9.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"28","RNA cell line specific nTPM":{"SCLC-21H":"58.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"14.5"},"Antibody":["HPA035443","HPA035444","HPA043203"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035443":"AB_2674625","HPA035444":"AB_10672093","HPA043203":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"9.7","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"6.0","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"16.6","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"6.8","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"17.1","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.2","Tissue RNA - white matter [nTPM]":"1.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"58.0","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"9.7","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"1.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CERS1","Gene synonym":["LAG1","LASS1","UOG1"],"Ensembl":"ENSG00000223802","Gene description":"Ceramide synthase 1","Uniprot":["P27544"],"Chromosome":"19","Position":"18868545-18896727","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"298.6","choroid plexus":"92.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"126.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"13.5","melanoma":"4.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"32.1","HEK 293":"34.7","NB-4":"39.3","NTERA-2":"25.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045724"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA045724":"AB_10969762"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"206.4","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"244.8","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"256.1","Tissue RNA - cerebral cortex [nTPM]":"216.6","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"92.2","Tissue RNA - colon [nTPM]":"3.5","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"218.8","Tissue RNA - hypothalamus [nTPM]":"200.4","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"298.6","Tissue RNA - midbrain [nTPM]":"233.8","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"12.8","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"240.9","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"4.8","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"21.3","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"247.7","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"29.3","Tissue RNA - thalamus [nTPM]":"251.3","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"12.3","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"1.7","Tissue RNA - white matter [nTPM]":"248.3","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"3.3","Cell RNA - AF22 [nTPM]":"19.1","Cell RNA - AN3-CA [nTPM]":"32.1","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"2.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.9","Cell RNA - CACO-2 [nTPM]":"15.7","Cell RNA - CAPAN-2 [nTPM]":"1.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"22.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.4","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"13.8","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"2.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"34.7","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"11.7","Cell RNA - HHSteC [nTPM]":"2.4","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.7","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"6.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.3","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"2.2","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"3.7","Cell RNA - MCF7 [nTPM]":"8.4","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"39.3","Cell RNA - NTERA-2 [nTPM]":"25.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"17.8","Cell RNA - SH-SY5Y [nTPM]":"15.8","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"14.1","Cell RNA - SuSa [nTPM]":"6.0","Cell RNA - T-47d [nTPM]":"5.5","Cell RNA - THP-1 [nTPM]":"20.5","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"3.4","Cell RNA - U-251 MG [nTPM]":"4.8","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"1.2","Cell RNA - WM-115 [nTPM]":"12.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"206.4","Brain RNA - basal ganglia [nTPM]":"244.8","Brain RNA - cerebellum [nTPM]":"256.1","Brain RNA - cerebral cortex [nTPM]":"216.6","Brain RNA - hippocampal formation [nTPM]":"218.8","Brain RNA - hypothalamus [nTPM]":"200.4","Brain RNA - medulla oblongata [nTPM]":"298.6","Brain RNA - midbrain [nTPM]":"233.8","Brain RNA - pons [nTPM]":"240.9","Brain RNA - spinal cord [nTPM]":"247.7","Brain RNA - thalamus [nTPM]":"251.3","Brain RNA - white matter [nTPM]":"248.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"21.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"126.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"10.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CFB","Gene synonym":["BF","BFD","H2-Bf"],"Ensembl":"ENSG00000243649","Gene description":"Complement factor B","Uniprot":["P00751"],"Chromosome":"6","Position":"31945650-31952084","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"liver":"2613.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"873.6","Exocrine glandular cells":"197.3","Hepatocytes":"284.0","Pancreatic endocrine cells":"318.0","Proximal enterocytes":"139.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"78.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"15.0","ASC TERT1":"23.0","EFO-21":"25.1","fHDF\/TERT166":"14.1","HSkMC":"19.1","U-87 MG":"10.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000951","HPA001817","HPA001832","CAB016381"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles","Cell Junctions"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":879000000,"Blood concentration - Conc. blood MS [pg\/L]":"120000000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB016381":"AB_627562","HPA000951":"AB_2797216","HPA001817":"AB_1078779","HPA001832":"AB_1078778"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"143.7","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"32.8","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"28.5","Tissue RNA - cerebellum [nTPM]":"3.4","Tissue RNA - cerebral cortex [nTPM]":"9.9","Tissue RNA - cervix [nTPM]":"16.3","Tissue RNA - choroid plexus [nTPM]":"3.9","Tissue RNA - colon [nTPM]":"22.3","Tissue RNA - duodenum [nTPM]":"28.1","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"14.2","Tissue RNA - esophagus [nTPM]":"24.1","Tissue RNA - fallopian tube [nTPM]":"53.7","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"42.6","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"58.7","Tissue RNA - liver [nTPM]":"2613.2","Tissue RNA - lung [nTPM]":"39.2","Tissue RNA - lymph node [nTPM]":"4.2","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"9.9","Tissue RNA - pancreas [nTPM]":"51.8","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"17.7","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"60.3","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"43.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"73.1","Tissue RNA - smooth muscle [nTPM]":"48.3","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"12.9","Tissue RNA - stomach 1 [nTPM]":"54.5","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"17.8","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"1.9","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"15.0","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"8.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"25.1","Cell RNA - fHDF\/TERT166 [nTPM]":"14.1","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"6.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.8","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"19.1","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"3.4","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"10.1","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"3.4","Brain RNA - cerebral cortex [nTPM]":"9.9","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"64.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"127.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"873.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"197.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"34.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"284.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"19.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"18.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"318.0","Single Cell Type RNA - Paneth cells [nTPM]":"10.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"139.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"75.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.4","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"CFH","Gene synonym":["ARMD4","ARMS1","FHL1","HF","HF1","HF2","HUS"],"Ensembl":"ENSG00000000971","Gene description":"Complement factor H","Uniprot":["P08603"],"Chromosome":"1","Position":"196652043-196747504","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Age-related macular degeneration","Cancer-related genes","Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"1676.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Fibroblasts":"448.0","Hepatocytes":"1114.8","Leydig cells":"283.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"151.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"18.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"T-cells":"18.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"123.1","HSkMC":"119.5","hTERT-RPE1":"374.9","RT4":"227.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016385","CAB016769","HPA038922","HPA049176","HPA053326"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":396000000000,"Blood concentration - Conc. blood MS [pg\/L]":"100000000000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB016385":"AB_627572","CAB016769":null,"HPA038922":"AB_2676271","HPA049176":"AB_2680663","HPA053326":"AB_2682113"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.92e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Tissue RNA - adipose tissue [nTPM]":"125.3","Tissue RNA - adrenal gland [nTPM]":"42.1","Tissue RNA - amygdala [nTPM]":"18.1","Tissue RNA - appendix [nTPM]":"32.7","Tissue RNA - basal ganglia [nTPM]":"21.5","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"66.9","Tissue RNA - cerebellum [nTPM]":"20.0","Tissue RNA - cerebral cortex [nTPM]":"29.6","Tissue RNA - cervix [nTPM]":"76.8","Tissue RNA - choroid plexus [nTPM]":"43.0","Tissue RNA - colon [nTPM]":"51.0","Tissue RNA - duodenum [nTPM]":"30.5","Tissue RNA - endometrium 1 [nTPM]":"12.8","Tissue RNA - epididymis [nTPM]":"15.9","Tissue RNA - esophagus [nTPM]":"63.8","Tissue RNA - fallopian tube [nTPM]":"24.2","Tissue RNA - gallbladder [nTPM]":"133.6","Tissue RNA - heart muscle [nTPM]":"301.5","Tissue RNA - hippocampal formation [nTPM]":"18.1","Tissue RNA - hypothalamus [nTPM]":"18.6","Tissue RNA - kidney [nTPM]":"25.5","Tissue RNA - liver [nTPM]":"1676.3","Tissue RNA - lung [nTPM]":"70.8","Tissue RNA - lymph node [nTPM]":"27.4","Tissue RNA - medulla oblongata [nTPM]":"19.3","Tissue RNA - midbrain [nTPM]":"19.0","Tissue RNA - ovary [nTPM]":"165.1","Tissue RNA - pancreas [nTPM]":"14.0","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"16.0","Tissue RNA - placenta [nTPM]":"26.1","Tissue RNA - pons [nTPM]":"19.9","Tissue RNA - prostate [nTPM]":"23.0","Tissue RNA - rectum [nTPM]":"80.2","Tissue RNA - retina [nTPM]":"4.3","Tissue RNA - salivary gland [nTPM]":"126.7","Tissue RNA - seminal vesicle [nTPM]":"24.0","Tissue RNA - skeletal muscle [nTPM]":"21.1","Tissue RNA - skin 1 [nTPM]":"74.5","Tissue RNA - small intestine [nTPM]":"52.1","Tissue RNA - smooth muscle [nTPM]":"32.5","Tissue RNA - spinal cord [nTPM]":"19.5","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"46.9","Tissue RNA - testis [nTPM]":"14.3","Tissue RNA - thalamus [nTPM]":"21.6","Tissue RNA - thymus [nTPM]":"12.1","Tissue RNA - thyroid gland [nTPM]":"102.5","Tissue RNA - tongue [nTPM]":"84.0","Tissue RNA - tonsil [nTPM]":"25.9","Tissue RNA - urinary bladder [nTPM]":"149.9","Tissue RNA - vagina [nTPM]":"27.0","Tissue RNA - white matter [nTPM]":"21.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"64.9","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"96.5","Cell RNA - ASC TERT1 [nTPM]":"54.7","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"25.8","Cell RNA - BJ hTERT+ [nTPM]":"63.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.5","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"11.9","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"9.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"23.6","Cell RNA - HBF TERT88 [nTPM]":"2.6","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"20.0","Cell RNA - HeLa [nTPM]":"74.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"123.1","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"119.5","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.4","Cell RNA - hTERT-HME1 [nTPM]":"7.9","Cell RNA - hTERT-RPE1 [nTPM]":"374.9","Cell RNA - HUVEC TERT2 [nTPM]":"79.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"74.4","Cell RNA - Karpas-707 [nTPM]":"2.7","Cell RNA - LHCN-M2 [nTPM]":"89.4","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"89.8","Cell RNA - RPMI-8226 [nTPM]":"21.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"227.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"73.6","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"13.1","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"5.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"18.7","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"18.1","Brain RNA - basal ganglia [nTPM]":"21.5","Brain RNA - cerebellum [nTPM]":"20.0","Brain RNA - cerebral cortex [nTPM]":"29.6","Brain RNA - hippocampal formation [nTPM]":"18.1","Brain RNA - hypothalamus [nTPM]":"18.6","Brain RNA - medulla oblongata [nTPM]":"19.3","Brain RNA - midbrain [nTPM]":"19.0","Brain RNA - pons [nTPM]":"19.9","Brain RNA - spinal cord [nTPM]":"19.5","Brain RNA - thalamus [nTPM]":"21.6","Brain RNA - white matter [nTPM]":"21.1","Single Cell Type RNA - Adipocytes [nTPM]":"73.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"4.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"63.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"140.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"141.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.8","Single Cell Type RNA - Endothelial cells [nTPM]":"49.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"52.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"448.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.9","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"6.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1114.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"43.8","Single Cell Type RNA - Langerhans cells [nTPM]":"62.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"283.9","Single Cell Type RNA - Macrophages [nTPM]":"5.7","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"138.8","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"115.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"94.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"59.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"13.2","Single Cell Type RNA - Theca cells [nTPM]":"26.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"61.5"},{"Gene":"CFHR1","Gene synonym":["CFHL","CFHL1","CFHL1P","CFHR1P","FHR1","H36-1","H36-2","HFL1","HFL2"],"Ensembl":"ENSG00000244414","Gene description":"Complement factor H related 1","Uniprot":["Q03591"],"Chromosome":"1","Position":"196819731-196832189","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"272","RNA tissue specific nTPM":{"liver":"2081.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hepatocytes":"320.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"798","RNA cancer specific FPKM":{"liver cancer":"182.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1.0","HeLa":"1.2","HL-60":"2.0","U-266\/70":"2.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038915","HPA038922","HPA040726"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA038915":"AB_2676269","HPA038922":"AB_2676271","HPA040726":"AB_2677101"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.71e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"7.6","Tissue RNA - liver [nTPM]":"2081.3","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"6.7","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"6.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"1.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"2.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"320.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"5.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CFHR3","Gene synonym":["CFHL3","DOWN16","FHR-3","FHR3","HLF4"],"Ensembl":"ENSG00000116785","Gene description":"Complement factor H related 3","Uniprot":["Q02985"],"Chromosome":"1","Position":"196774813-196795407","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"582","RNA tissue specific nTPM":{"liver":"505.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Hepatocytes":"205.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"80","RNA cancer specific FPKM":{"liver cancer":"27.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"1.7","SuSa":"1.5","T-47d":"3.6","U-266\/70":"6.4"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":582000000,"Blood concentration - Conc. blood MS [pg\/L]":"3100000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.86e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"505.7","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"3.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"205.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"CFI","Gene synonym":["C3b-INA","FI","IF","KAF"],"Ensembl":"ENSG00000205403","Gene description":"Complement factor I","Uniprot":["P05156"],"Chromosome":"4","Position":"109740694-109801999","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Complement pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"1098.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"108.7","Hepatocytes":"592.5","Muller glia cells":"147.8","Proximal tubular cells":"223.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"90.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"106.1","Hep G2":"179.8","HSkMC":"67.4","RPTEC TERT1":"190.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001143","CAB016777","HPA024061"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016777":null,"HPA001143":"AB_1078555","HPA024061":"AB_1847129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.06e-4"},"Tissue RNA - adipose tissue [nTPM]":"45.1","Tissue RNA - adrenal gland [nTPM]":"50.2","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"12.6","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"17.4","Tissue RNA - cerebellum [nTPM]":"7.7","Tissue RNA - cerebral cortex [nTPM]":"13.2","Tissue RNA - cervix [nTPM]":"36.8","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"38.0","Tissue RNA - endometrium 1 [nTPM]":"39.2","Tissue RNA - epididymis [nTPM]":"80.3","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"74.0","Tissue RNA - gallbladder [nTPM]":"73.0","Tissue RNA - heart muscle [nTPM]":"25.0","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"224.9","Tissue RNA - liver [nTPM]":"1098.8","Tissue RNA - lung [nTPM]":"50.7","Tissue RNA - lymph node [nTPM]":"8.9","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"32.1","Tissue RNA - pancreas [nTPM]":"26.0","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"24.1","Tissue RNA - pons [nTPM]":"10.7","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"53.0","Tissue RNA - salivary gland [nTPM]":"15.0","Tissue RNA - seminal vesicle [nTPM]":"26.7","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"22.3","Tissue RNA - smooth muscle [nTPM]":"24.3","Tissue RNA - spinal cord [nTPM]":"10.5","Tissue RNA - spleen [nTPM]":"33.1","Tissue RNA - stomach 1 [nTPM]":"14.4","Tissue RNA - testis [nTPM]":"8.8","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"14.5","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"34.1","Tissue RNA - vagina [nTPM]":"8.3","Tissue RNA - white matter [nTPM]":"10.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"106.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"32.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"34.8","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"179.8","Cell RNA - HHSteC [nTPM]":"6.2","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"67.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.6","Cell RNA - HUVEC TERT2 [nTPM]":"4.8","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"190.6","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"18.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"7.7","Brain RNA - cerebral cortex [nTPM]":"13.2","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"10.7","Brain RNA - spinal cord [nTPM]":"10.5","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"10.6","Single Cell Type RNA - Adipocytes [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"50.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"4.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"108.7","Single Cell Type RNA - Club cells [nTPM]":"36.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"64.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"69.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.4","Single Cell Type RNA - Endothelial cells [nTPM]":"57.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"34.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"72.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.0","Single Cell Type RNA - Hepatocytes [nTPM]":"592.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"2.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"147.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.8","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"223.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"3.4","Single Cell Type RNA - Theca cells [nTPM]":"18.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"CHAT","Gene synonym":[],"Ensembl":"ENSG00000070748","Gene description":"Choline O-acetyltransferase","Uniprot":["P28329"],"Chromosome":"10","Position":"49609095-49667942","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Neurotransmitter biosynthesis"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"13.0","placenta":"5.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"NB-4":"20.9"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"20.6"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"basal ganglia":"6.5","pons":"7.0","spinal cord":"12.0"},"Antibody":["CAB002313","HPA048547","CAB079053"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002313":"AB_563661","CAB079053":null,"HPA048547":"AB_2680437"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"13.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"7.9","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"5.5","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"20.9","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"13.0","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"7.9","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CHCHD10","Gene synonym":["C22orf16","MIX17A","N27C7-4"],"Ensembl":"ENSG00000250479","Gene description":"Coiled-coil-helix-coiled-coil-helix domain containing 10","Uniprot":["Q8WYQ3"],"Chromosome":"22","Position":"23765834-23767972","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"1622.6","skeletal muscle":"1220.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1264.7","Distal tubular cells":"2498.5","Hepatocytes":"1879.9","Proximal enterocytes":"1501.3","Proximal tubular cells":"1437.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003440"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA003440":"AB_1078348"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.15e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-3"},"Tissue RNA - adipose tissue [nTPM]":"216.5","Tissue RNA - adrenal gland [nTPM]":"136.5","Tissue RNA - amygdala [nTPM]":"181.6","Tissue RNA - appendix [nTPM]":"30.3","Tissue RNA - basal ganglia [nTPM]":"188.3","Tissue RNA - bone marrow [nTPM]":"12.5","Tissue RNA - breast [nTPM]":"144.5","Tissue RNA - cerebellum [nTPM]":"183.0","Tissue RNA - cerebral cortex [nTPM]":"248.9","Tissue RNA - cervix [nTPM]":"77.3","Tissue RNA - choroid plexus [nTPM]":"262.6","Tissue RNA - colon [nTPM]":"261.2","Tissue RNA - duodenum [nTPM]":"92.6","Tissue RNA - endometrium 1 [nTPM]":"35.5","Tissue RNA - epididymis [nTPM]":"32.4","Tissue RNA - esophagus [nTPM]":"147.3","Tissue RNA - fallopian tube [nTPM]":"43.1","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"1622.6","Tissue RNA - hippocampal formation [nTPM]":"176.6","Tissue RNA - hypothalamus [nTPM]":"190.5","Tissue RNA - kidney [nTPM]":"409.5","Tissue RNA - liver [nTPM]":"789.7","Tissue RNA - lung [nTPM]":"56.9","Tissue RNA - lymph node [nTPM]":"28.6","Tissue RNA - medulla oblongata [nTPM]":"182.2","Tissue RNA - midbrain [nTPM]":"182.2","Tissue RNA - ovary [nTPM]":"29.0","Tissue RNA - pancreas [nTPM]":"118.0","Tissue RNA - parathyroid gland [nTPM]":"220.0","Tissue RNA - pituitary gland [nTPM]":"112.3","Tissue RNA - placenta [nTPM]":"11.9","Tissue RNA - pons [nTPM]":"187.6","Tissue RNA - prostate [nTPM]":"106.4","Tissue RNA - rectum [nTPM]":"76.2","Tissue RNA - retina [nTPM]":"63.1","Tissue RNA - salivary gland [nTPM]":"148.3","Tissue RNA - seminal vesicle [nTPM]":"50.5","Tissue RNA - skeletal muscle [nTPM]":"1220.9","Tissue RNA - skin 1 [nTPM]":"71.8","Tissue RNA - small intestine [nTPM]":"159.0","Tissue RNA - smooth muscle [nTPM]":"17.9","Tissue RNA - spinal cord [nTPM]":"169.5","Tissue RNA - spleen [nTPM]":"100.3","Tissue RNA - stomach 1 [nTPM]":"160.2","Tissue RNA - testis [nTPM]":"27.8","Tissue RNA - thalamus [nTPM]":"204.8","Tissue RNA - thymus [nTPM]":"14.0","Tissue RNA - thyroid gland [nTPM]":"224.7","Tissue RNA - tongue [nTPM]":"660.7","Tissue RNA - tonsil [nTPM]":"34.5","Tissue RNA - urinary bladder [nTPM]":"110.2","Tissue RNA - vagina [nTPM]":"89.1","Tissue RNA - white matter [nTPM]":"179.3","Cell RNA - A-431 [nTPM]":"33.1","Cell RNA - A549 [nTPM]":"66.4","Cell RNA - AF22 [nTPM]":"19.7","Cell RNA - AN3-CA [nTPM]":"85.9","Cell RNA - ASC diff [nTPM]":"42.1","Cell RNA - ASC TERT1 [nTPM]":"27.7","Cell RNA - BEWO [nTPM]":"41.9","Cell RNA - BJ [nTPM]":"11.9","Cell RNA - BJ hTERT+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.4","Cell RNA - CACO-2 [nTPM]":"124.1","Cell RNA - CAPAN-2 [nTPM]":"35.1","Cell RNA - Daudi [nTPM]":"113.5","Cell RNA - EFO-21 [nTPM]":"30.7","Cell RNA - fHDF\/TERT166 [nTPM]":"41.2","Cell RNA - GAMG [nTPM]":"12.9","Cell RNA - HaCaT [nTPM]":"99.8","Cell RNA - HAP1 [nTPM]":"109.2","Cell RNA - HBEC3-KT [nTPM]":"34.1","Cell RNA - HBF TERT88 [nTPM]":"20.5","Cell RNA - HDLM-2 [nTPM]":"35.9","Cell RNA - HEK 293 [nTPM]":"140.6","Cell RNA - HEL [nTPM]":"22.5","Cell RNA - HeLa [nTPM]":"48.8","Cell RNA - Hep G2 [nTPM]":"117.1","Cell RNA - HHSteC [nTPM]":"73.8","Cell RNA - HL-60 [nTPM]":"63.6","Cell RNA - HMC-1 [nTPM]":"108.2","Cell RNA - HSkMC [nTPM]":"53.3","Cell RNA - hTCEpi [nTPM]":"91.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.6","Cell RNA - hTERT-HME1 [nTPM]":"9.3","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"29.0","Cell RNA - JURKAT [nTPM]":"17.2","Cell RNA - K-562 [nTPM]":"47.7","Cell RNA - Karpas-707 [nTPM]":"48.0","Cell RNA - LHCN-M2 [nTPM]":"20.6","Cell RNA - MCF7 [nTPM]":"121.8","Cell RNA - MOLT-4 [nTPM]":"21.8","Cell RNA - NB-4 [nTPM]":"48.2","Cell RNA - NTERA-2 [nTPM]":"16.9","Cell RNA - OE19 [nTPM]":"194.9","Cell RNA - PC-3 [nTPM]":"183.5","Cell RNA - REH [nTPM]":"90.0","Cell RNA - RH-30 [nTPM]":"4.0","Cell RNA - RPMI-8226 [nTPM]":"209.0","Cell RNA - RPTEC TERT1 [nTPM]":"112.7","Cell RNA - RT4 [nTPM]":"55.3","Cell RNA - SCLC-21H [nTPM]":"41.3","Cell RNA - SH-SY5Y [nTPM]":"23.8","Cell RNA - SiHa [nTPM]":"13.9","Cell RNA - SK-BR-3 [nTPM]":"145.7","Cell RNA - SK-MEL-30 [nTPM]":"149.7","Cell RNA - SuSa [nTPM]":"36.6","Cell RNA - T-47d [nTPM]":"54.9","Cell RNA - THP-1 [nTPM]":"47.0","Cell RNA - TIME [nTPM]":"15.3","Cell RNA - U-138 MG [nTPM]":"1.0","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"18.3","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"28.8","Cell RNA - U-266\/84 [nTPM]":"11.1","Cell RNA - U-698 [nTPM]":"62.5","Cell RNA - U-87 MG [nTPM]":"20.5","Cell RNA - U-937 [nTPM]":"54.9","Cell RNA - WM-115 [nTPM]":"11.2","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"4.1","Blood RNA - eosinophil [nTPM]":"11.2","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"9.1","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"11.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"10.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"8.2","Blood RNA - plasmacytoid DC [nTPM]":"7.3","Blood RNA - T-reg [nTPM]":"4.3","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"181.6","Brain RNA - basal ganglia [nTPM]":"188.3","Brain RNA - cerebellum [nTPM]":"183.0","Brain RNA - cerebral cortex [nTPM]":"248.9","Brain RNA - hippocampal formation [nTPM]":"176.6","Brain RNA - hypothalamus [nTPM]":"190.5","Brain RNA - medulla oblongata [nTPM]":"182.2","Brain RNA - midbrain [nTPM]":"182.2","Brain RNA - pons [nTPM]":"187.6","Brain RNA - spinal cord [nTPM]":"169.5","Brain RNA - thalamus [nTPM]":"204.8","Brain RNA - white matter [nTPM]":"179.3","Single Cell Type RNA - Adipocytes [nTPM]":"88.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.5","Single Cell Type RNA - Astrocytes [nTPM]":"36.2","Single Cell Type RNA - B-cells [nTPM]":"294.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"48.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"415.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"144.5","Single Cell Type RNA - Bipolar cells [nTPM]":"136.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"156.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"238.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"503.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"268.8","Single Cell Type RNA - Club cells [nTPM]":"20.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"419.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"114.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.5","Single Cell Type RNA - dendritic cells [nTPM]":"104.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"1264.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"2498.5","Single Cell Type RNA - Ductal cells [nTPM]":"88.1","Single Cell Type RNA - Early spermatids [nTPM]":"27.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"76.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"229.8","Single Cell Type RNA - Endothelial cells [nTPM]":"47.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"310.5","Single Cell Type RNA - Erythroid cells [nTPM]":"74.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"54.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"255.7","Single Cell Type RNA - Fibroblasts [nTPM]":"67.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"300.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"94.3","Single Cell Type RNA - granulocytes [nTPM]":"84.0","Single Cell Type RNA - Granulosa cells [nTPM]":"171.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"78.1","Single Cell Type RNA - Hepatocytes [nTPM]":"1879.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"647.5","Single Cell Type RNA - Horizontal cells [nTPM]":"99.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"860.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"262.1","Single Cell Type RNA - Langerhans cells [nTPM]":"127.5","Single Cell Type RNA - Late spermatids [nTPM]":"18.0","Single Cell Type RNA - Leydig cells [nTPM]":"48.7","Single Cell Type RNA - Macrophages [nTPM]":"243.1","Single Cell Type RNA - Melanocytes [nTPM]":"373.5","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"107.8","Single Cell Type RNA - Muller glia cells [nTPM]":"188.5","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.9","Single Cell Type RNA - Paneth cells [nTPM]":"890.1","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"297.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"192.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1501.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1437.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"287.8","Single Cell Type RNA - Sertoli cells [nTPM]":"124.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"254.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"200.4","Single Cell Type RNA - Spermatocytes [nTPM]":"32.3","Single Cell Type RNA - Spermatogonia [nTPM]":"43.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"459.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"105.2","Single Cell Type RNA - T-cells [nTPM]":"123.0","Single Cell Type RNA - Theca cells [nTPM]":"216.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"952.4","Single Cell Type RNA - Urothelial cells [nTPM]":"470.1"},{"Gene":"CHCHD2","Gene synonym":["C7orf17","MIX17B","MNRR1"],"Ensembl":"ENSG00000106153","Gene description":"Coiled-coil-helix-coiled-coil-helix domain containing 2","Uniprot":["Q9Y6H1"],"Chromosome":"7","Position":"56101573-56106476","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription"],"Molecular function":["Activator"],"Disease involvement":["Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"3195.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027407","HPA052510"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA027407":"AB_10959659","HPA052510":"AB_2681856"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"250.6","Tissue RNA - adrenal gland [nTPM]":"665.5","Tissue RNA - amygdala [nTPM]":"321.4","Tissue RNA - appendix [nTPM]":"167.4","Tissue RNA - basal ganglia [nTPM]":"331.8","Tissue RNA - bone marrow [nTPM]":"426.3","Tissue RNA - breast [nTPM]":"253.9","Tissue RNA - cerebellum [nTPM]":"361.8","Tissue RNA - cerebral cortex [nTPM]":"358.5","Tissue RNA - cervix [nTPM]":"220.7","Tissue RNA - choroid plexus [nTPM]":"351.0","Tissue RNA - colon [nTPM]":"257.6","Tissue RNA - duodenum [nTPM]":"252.0","Tissue RNA - endometrium 1 [nTPM]":"219.0","Tissue RNA - epididymis [nTPM]":"252.4","Tissue RNA - esophagus [nTPM]":"269.6","Tissue RNA - fallopian tube [nTPM]":"210.6","Tissue RNA - gallbladder [nTPM]":"132.1","Tissue RNA - heart muscle [nTPM]":"412.4","Tissue RNA - hippocampal formation [nTPM]":"325.3","Tissue RNA - hypothalamus [nTPM]":"352.7","Tissue RNA - kidney [nTPM]":"349.4","Tissue RNA - liver [nTPM]":"316.7","Tissue RNA - lung [nTPM]":"213.8","Tissue RNA - lymph node [nTPM]":"205.0","Tissue RNA - medulla oblongata [nTPM]":"340.1","Tissue RNA - midbrain [nTPM]":"341.5","Tissue RNA - ovary [nTPM]":"246.3","Tissue RNA - pancreas [nTPM]":"315.9","Tissue RNA - parathyroid gland [nTPM]":"322.9","Tissue RNA - pituitary gland [nTPM]":"272.3","Tissue RNA - placenta [nTPM]":"151.8","Tissue RNA - pons [nTPM]":"343.2","Tissue RNA - prostate [nTPM]":"237.2","Tissue RNA - rectum [nTPM]":"191.7","Tissue RNA - retina [nTPM]":"226.2","Tissue RNA - salivary gland [nTPM]":"281.2","Tissue RNA - seminal vesicle [nTPM]":"196.7","Tissue RNA - skeletal muscle [nTPM]":"791.4","Tissue RNA - skin 1 [nTPM]":"233.3","Tissue RNA - small intestine [nTPM]":"243.9","Tissue RNA - smooth muscle [nTPM]":"150.5","Tissue RNA - spinal cord [nTPM]":"354.6","Tissue RNA - spleen [nTPM]":"223.3","Tissue RNA - stomach 1 [nTPM]":"287.6","Tissue RNA - testis [nTPM]":"120.7","Tissue RNA - thalamus [nTPM]":"352.2","Tissue RNA - thymus [nTPM]":"267.7","Tissue RNA - thyroid gland [nTPM]":"208.2","Tissue RNA - tongue [nTPM]":"591.3","Tissue RNA - tonsil [nTPM]":"200.2","Tissue RNA - urinary bladder [nTPM]":"217.8","Tissue RNA - vagina [nTPM]":"214.2","Tissue RNA - white matter [nTPM]":"367.9","Cell RNA - A-431 [nTPM]":"3195.8","Cell RNA - A549 [nTPM]":"553.5","Cell RNA - AF22 [nTPM]":"351.8","Cell RNA - AN3-CA [nTPM]":"732.5","Cell RNA - ASC diff [nTPM]":"275.9","Cell RNA - ASC TERT1 [nTPM]":"379.3","Cell RNA - BEWO [nTPM]":"261.7","Cell RNA - BJ [nTPM]":"456.7","Cell RNA - BJ hTERT+ [nTPM]":"436.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"584.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"561.3","Cell RNA - CACO-2 [nTPM]":"513.0","Cell RNA - CAPAN-2 [nTPM]":"517.4","Cell RNA - Daudi [nTPM]":"932.1","Cell RNA - EFO-21 [nTPM]":"589.1","Cell RNA - fHDF\/TERT166 [nTPM]":"285.1","Cell RNA - GAMG [nTPM]":"741.3","Cell RNA - HaCaT [nTPM]":"527.6","Cell RNA - HAP1 [nTPM]":"456.5","Cell RNA - HBEC3-KT [nTPM]":"507.4","Cell RNA - HBF TERT88 [nTPM]":"469.6","Cell RNA - HDLM-2 [nTPM]":"609.1","Cell RNA - HEK 293 [nTPM]":"831.5","Cell RNA - HEL [nTPM]":"549.2","Cell RNA - HeLa [nTPM]":"422.0","Cell RNA - Hep G2 [nTPM]":"738.9","Cell RNA - HHSteC [nTPM]":"510.5","Cell RNA - HL-60 [nTPM]":"745.9","Cell RNA - HMC-1 [nTPM]":"844.8","Cell RNA - HSkMC [nTPM]":"339.1","Cell RNA - hTCEpi [nTPM]":"571.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"438.0","Cell RNA - hTERT-HME1 [nTPM]":"532.4","Cell RNA - hTERT-RPE1 [nTPM]":"312.3","Cell RNA - HUVEC TERT2 [nTPM]":"444.1","Cell RNA - JURKAT [nTPM]":"800.3","Cell RNA - K-562 [nTPM]":"1182.9","Cell RNA - Karpas-707 [nTPM]":"546.7","Cell RNA - LHCN-M2 [nTPM]":"486.4","Cell RNA - MCF7 [nTPM]":"449.9","Cell RNA - MOLT-4 [nTPM]":"1007.2","Cell RNA - NB-4 [nTPM]":"2306.5","Cell RNA - NTERA-2 [nTPM]":"760.6","Cell RNA - OE19 [nTPM]":"867.3","Cell RNA - PC-3 [nTPM]":"872.6","Cell RNA - REH [nTPM]":"668.3","Cell RNA - RH-30 [nTPM]":"343.3","Cell RNA - RPMI-8226 [nTPM]":"1539.3","Cell RNA - RPTEC TERT1 [nTPM]":"532.5","Cell RNA - RT4 [nTPM]":"417.0","Cell RNA - SCLC-21H [nTPM]":"671.5","Cell RNA - SH-SY5Y [nTPM]":"834.3","Cell RNA - SiHa [nTPM]":"360.6","Cell RNA - SK-BR-3 [nTPM]":"874.7","Cell RNA - SK-MEL-30 [nTPM]":"597.1","Cell RNA - SuSa [nTPM]":"239.4","Cell RNA - T-47d [nTPM]":"1002.5","Cell RNA - THP-1 [nTPM]":"1046.8","Cell RNA - TIME [nTPM]":"354.2","Cell RNA - U-138 MG [nTPM]":"354.2","Cell RNA - U-2 OS [nTPM]":"823.5","Cell RNA - U-2197 [nTPM]":"1473.9","Cell RNA - U-251 MG [nTPM]":"683.6","Cell RNA - U-266\/70 [nTPM]":"497.1","Cell RNA - U-266\/84 [nTPM]":"785.4","Cell RNA - U-698 [nTPM]":"1698.9","Cell RNA - U-87 MG [nTPM]":"555.3","Cell RNA - U-937 [nTPM]":"802.0","Cell RNA - WM-115 [nTPM]":"448.0","Blood RNA - basophil [nTPM]":"354.1","Blood RNA - classical monocyte [nTPM]":"509.1","Blood RNA - eosinophil [nTPM]":"400.6","Blood RNA - gdT-cell [nTPM]":"362.1","Blood RNA - intermediate monocyte [nTPM]":"458.7","Blood RNA - MAIT T-cell [nTPM]":"377.4","Blood RNA - memory B-cell [nTPM]":"461.2","Blood RNA - memory CD4 T-cell [nTPM]":"387.4","Blood RNA - memory CD8 T-cell [nTPM]":"387.2","Blood RNA - myeloid DC [nTPM]":"575.8","Blood RNA - naive B-cell [nTPM]":"435.0","Blood RNA - naive CD4 T-cell [nTPM]":"344.9","Blood RNA - naive CD8 T-cell [nTPM]":"354.9","Blood RNA - neutrophil [nTPM]":"268.0","Blood RNA - NK-cell [nTPM]":"400.9","Blood RNA - non-classical monocyte [nTPM]":"467.1","Blood RNA - plasmacytoid DC [nTPM]":"785.2","Blood RNA - T-reg [nTPM]":"550.9","Blood RNA - total PBMC [nTPM]":"1066.7","Brain RNA - amygdala [nTPM]":"321.4","Brain RNA - basal ganglia [nTPM]":"331.8","Brain RNA - cerebellum [nTPM]":"361.8","Brain RNA - cerebral cortex [nTPM]":"358.5","Brain RNA - hippocampal formation [nTPM]":"325.3","Brain RNA - hypothalamus [nTPM]":"352.7","Brain RNA - medulla oblongata [nTPM]":"340.1","Brain RNA - midbrain [nTPM]":"341.5","Brain RNA - pons [nTPM]":"343.2","Brain RNA - spinal cord [nTPM]":"354.6","Brain RNA - thalamus [nTPM]":"352.2","Brain RNA - white matter [nTPM]":"367.9","Single Cell Type RNA - Adipocytes [nTPM]":"465.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"256.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"284.0","Single Cell Type RNA - Astrocytes [nTPM]":"44.4","Single Cell Type RNA - B-cells [nTPM]":"521.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"717.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"956.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1072.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"387.0","Single Cell Type RNA - Bipolar cells [nTPM]":"348.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"758.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"929.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"160.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"513.3","Single Cell Type RNA - Club cells [nTPM]":"612.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"413.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"955.1","Single Cell Type RNA - dendritic cells [nTPM]":"577.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"807.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1860.7","Single Cell Type RNA - Ductal cells [nTPM]":"1034.0","Single Cell Type RNA - Early spermatids [nTPM]":"167.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"593.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"396.0","Single Cell Type RNA - Endothelial cells [nTPM]":"446.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"541.2","Single Cell Type RNA - Erythroid cells [nTPM]":"666.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1325.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1259.9","Single Cell Type RNA - Fibroblasts [nTPM]":"514.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"393.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"622.8","Single Cell Type RNA - granulocytes [nTPM]":"394.3","Single Cell Type RNA - Granulosa cells [nTPM]":"458.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"377.0","Single Cell Type RNA - Hepatocytes [nTPM]":"727.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"969.6","Single Cell Type RNA - Horizontal cells [nTPM]":"492.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"973.0","Single Cell Type RNA - Ionocytes [nTPM]":"752.7","Single Cell Type RNA - Kupffer cells [nTPM]":"483.5","Single Cell Type RNA - Langerhans cells [nTPM]":"701.2","Single Cell Type RNA - Late spermatids [nTPM]":"213.4","Single Cell Type RNA - Leydig cells [nTPM]":"614.2","Single Cell Type RNA - Macrophages [nTPM]":"496.2","Single Cell Type RNA - Melanocytes [nTPM]":"763.1","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"806.5","Single Cell Type RNA - Muller glia cells [nTPM]":"769.6","Single Cell Type RNA - NK-cells [nTPM]":"593.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1190.3","Single Cell Type RNA - Paneth cells [nTPM]":"974.5","Single Cell Type RNA - Peritubular cells [nTPM]":"505.9","Single Cell Type RNA - Plasma cells [nTPM]":"803.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1321.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1138.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1558.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"559.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"353.7","Single Cell Type RNA - Sertoli cells [nTPM]":"427.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"620.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"583.8","Single Cell Type RNA - Spermatocytes [nTPM]":"520.4","Single Cell Type RNA - Spermatogonia [nTPM]":"574.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"680.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"719.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1228.8","Single Cell Type RNA - T-cells [nTPM]":"492.5","Single Cell Type RNA - Theca cells [nTPM]":"633.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"929.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1464.2"},{"Gene":"CHD2","Gene synonym":["DKFZp547I1315","DKFZp686E01200","DKFZp781D1727","FLJ38614"],"Ensembl":"ENSG00000173575","Gene description":"Chromodomain helicase DNA binding protein 2","Uniprot":["O14647"],"Chromosome":"15","Position":"92900189-93027996","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Myogenesis","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060744","HPA060960"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA060744":"AB_2684353","HPA060960":"AB_2684398"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.9","Tissue RNA - adrenal gland [nTPM]":"12.3","Tissue RNA - amygdala [nTPM]":"22.7","Tissue RNA - appendix [nTPM]":"20.7","Tissue RNA - basal ganglia [nTPM]":"25.5","Tissue RNA - bone marrow [nTPM]":"73.5","Tissue RNA - breast [nTPM]":"20.4","Tissue RNA - cerebellum [nTPM]":"42.0","Tissue RNA - cerebral cortex [nTPM]":"32.7","Tissue RNA - cervix [nTPM]":"15.7","Tissue RNA - choroid plexus [nTPM]":"32.0","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"14.8","Tissue RNA - endometrium 1 [nTPM]":"19.4","Tissue RNA - epididymis [nTPM]":"29.1","Tissue RNA - esophagus [nTPM]":"14.6","Tissue RNA - fallopian tube [nTPM]":"16.2","Tissue RNA - gallbladder [nTPM]":"15.6","Tissue RNA - heart muscle [nTPM]":"12.0","Tissue RNA - hippocampal formation [nTPM]":"21.3","Tissue RNA - hypothalamus [nTPM]":"24.7","Tissue RNA - kidney [nTPM]":"16.9","Tissue RNA - liver [nTPM]":"15.4","Tissue RNA - lung [nTPM]":"21.6","Tissue RNA - lymph node [nTPM]":"26.4","Tissue RNA - medulla oblongata [nTPM]":"29.0","Tissue RNA - midbrain [nTPM]":"23.3","Tissue RNA - ovary [nTPM]":"26.1","Tissue RNA - pancreas [nTPM]":"19.6","Tissue RNA - parathyroid gland [nTPM]":"18.2","Tissue RNA - pituitary gland [nTPM]":"16.6","Tissue RNA - placenta [nTPM]":"20.5","Tissue RNA - pons [nTPM]":"24.5","Tissue RNA - prostate [nTPM]":"20.4","Tissue RNA - rectum [nTPM]":"14.8","Tissue RNA - retina [nTPM]":"30.8","Tissue RNA - salivary gland [nTPM]":"21.2","Tissue RNA - seminal vesicle [nTPM]":"13.4","Tissue RNA - skeletal muscle [nTPM]":"17.4","Tissue RNA - skin 1 [nTPM]":"18.8","Tissue RNA - small intestine [nTPM]":"18.7","Tissue RNA - smooth muscle [nTPM]":"13.3","Tissue RNA - spinal cord [nTPM]":"22.1","Tissue RNA - spleen [nTPM]":"23.3","Tissue RNA - stomach 1 [nTPM]":"17.7","Tissue RNA - testis [nTPM]":"20.8","Tissue RNA - thalamus [nTPM]":"25.9","Tissue RNA - thymus [nTPM]":"27.0","Tissue RNA - thyroid gland [nTPM]":"26.3","Tissue RNA - tongue [nTPM]":"14.7","Tissue RNA - tonsil [nTPM]":"25.4","Tissue RNA - urinary bladder [nTPM]":"13.7","Tissue RNA - vagina [nTPM]":"16.1","Tissue RNA - white matter [nTPM]":"27.6","Cell RNA - A-431 [nTPM]":"21.3","Cell RNA - A549 [nTPM]":"11.6","Cell RNA - AF22 [nTPM]":"30.6","Cell RNA - AN3-CA [nTPM]":"13.6","Cell RNA - ASC diff [nTPM]":"17.9","Cell RNA - ASC TERT1 [nTPM]":"45.3","Cell RNA - BEWO [nTPM]":"23.0","Cell RNA - BJ [nTPM]":"19.4","Cell RNA - BJ hTERT+ [nTPM]":"20.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.1","Cell RNA - CACO-2 [nTPM]":"14.5","Cell RNA - CAPAN-2 [nTPM]":"27.4","Cell RNA - Daudi [nTPM]":"5.2","Cell RNA - EFO-21 [nTPM]":"16.1","Cell RNA - fHDF\/TERT166 [nTPM]":"17.3","Cell RNA - GAMG [nTPM]":"22.1","Cell RNA - HaCaT [nTPM]":"31.1","Cell RNA - HAP1 [nTPM]":"17.6","Cell RNA - HBEC3-KT [nTPM]":"19.5","Cell RNA - HBF TERT88 [nTPM]":"18.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"10.6","Cell RNA - HEL [nTPM]":"25.3","Cell RNA - HeLa [nTPM]":"26.1","Cell RNA - Hep G2 [nTPM]":"12.9","Cell RNA - HHSteC [nTPM]":"24.6","Cell RNA - HL-60 [nTPM]":"27.1","Cell RNA - HMC-1 [nTPM]":"19.0","Cell RNA - HSkMC [nTPM]":"28.7","Cell RNA - hTCEpi [nTPM]":"23.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.5","Cell RNA - hTERT-HME1 [nTPM]":"31.1","Cell RNA - hTERT-RPE1 [nTPM]":"26.8","Cell RNA - HUVEC TERT2 [nTPM]":"22.4","Cell RNA - JURKAT [nTPM]":"36.7","Cell RNA - K-562 [nTPM]":"26.8","Cell RNA - Karpas-707 [nTPM]":"57.1","Cell RNA - LHCN-M2 [nTPM]":"19.9","Cell RNA - MCF7 [nTPM]":"13.1","Cell RNA - MOLT-4 [nTPM]":"14.2","Cell RNA - NB-4 [nTPM]":"14.0","Cell RNA - NTERA-2 [nTPM]":"19.5","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"12.6","Cell RNA - REH [nTPM]":"19.9","Cell RNA - RH-30 [nTPM]":"27.6","Cell RNA - RPMI-8226 [nTPM]":"28.4","Cell RNA - RPTEC TERT1 [nTPM]":"13.3","Cell RNA - RT4 [nTPM]":"28.5","Cell RNA - SCLC-21H [nTPM]":"16.8","Cell RNA - SH-SY5Y [nTPM]":"18.1","Cell RNA - SiHa [nTPM]":"34.2","Cell RNA - SK-BR-3 [nTPM]":"12.3","Cell RNA - SK-MEL-30 [nTPM]":"25.9","Cell RNA - SuSa [nTPM]":"30.6","Cell RNA - T-47d [nTPM]":"14.1","Cell RNA - THP-1 [nTPM]":"22.6","Cell RNA - TIME [nTPM]":"36.2","Cell RNA - U-138 MG [nTPM]":"10.7","Cell RNA - U-2 OS [nTPM]":"13.9","Cell RNA - U-2197 [nTPM]":"9.3","Cell RNA - U-251 MG [nTPM]":"12.8","Cell RNA - U-266\/70 [nTPM]":"53.4","Cell RNA - U-266\/84 [nTPM]":"23.2","Cell RNA - U-698 [nTPM]":"21.6","Cell RNA - U-87 MG [nTPM]":"15.9","Cell RNA - U-937 [nTPM]":"15.9","Cell RNA - WM-115 [nTPM]":"9.4","Blood RNA - basophil [nTPM]":"35.9","Blood RNA - classical monocyte [nTPM]":"10.8","Blood RNA - eosinophil [nTPM]":"27.7","Blood RNA - gdT-cell [nTPM]":"22.1","Blood RNA - intermediate monocyte [nTPM]":"6.6","Blood RNA - MAIT T-cell [nTPM]":"21.8","Blood RNA - memory B-cell [nTPM]":"48.7","Blood RNA - memory CD4 T-cell [nTPM]":"21.5","Blood RNA - memory CD8 T-cell [nTPM]":"20.5","Blood RNA - myeloid DC [nTPM]":"7.4","Blood RNA - naive B-cell [nTPM]":"39.6","Blood RNA - naive CD4 T-cell [nTPM]":"30.1","Blood RNA - naive CD8 T-cell [nTPM]":"22.1","Blood RNA - neutrophil [nTPM]":"53.7","Blood RNA - NK-cell [nTPM]":"20.6","Blood RNA - non-classical monocyte [nTPM]":"13.4","Blood RNA - plasmacytoid DC [nTPM]":"27.9","Blood RNA - T-reg [nTPM]":"24.9","Blood RNA - total PBMC [nTPM]":"10.9","Brain RNA - amygdala [nTPM]":"22.7","Brain RNA - basal ganglia [nTPM]":"25.5","Brain RNA - cerebellum [nTPM]":"42.0","Brain RNA - cerebral cortex [nTPM]":"32.7","Brain RNA - hippocampal formation [nTPM]":"21.3","Brain RNA - hypothalamus [nTPM]":"24.7","Brain RNA - medulla oblongata [nTPM]":"29.0","Brain RNA - midbrain [nTPM]":"23.3","Brain RNA - pons [nTPM]":"24.5","Brain RNA - spinal cord [nTPM]":"22.1","Brain RNA - thalamus [nTPM]":"25.9","Brain RNA - white matter [nTPM]":"27.6","Single Cell Type RNA - Adipocytes [nTPM]":"59.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"176.3","Single Cell Type RNA - Astrocytes [nTPM]":"182.2","Single Cell Type RNA - B-cells [nTPM]":"137.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"164.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"112.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"153.7","Single Cell Type RNA - Bipolar cells [nTPM]":"71.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"62.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"46.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"42.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"137.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"91.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.7","Single Cell Type RNA - dendritic cells [nTPM]":"116.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"59.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"36.1","Single Cell Type RNA - Early spermatids [nTPM]":"56.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"96.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"61.7","Single Cell Type RNA - Endothelial cells [nTPM]":"58.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"59.3","Single Cell Type RNA - Erythroid cells [nTPM]":"65.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"161.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.5","Single Cell Type RNA - Fibroblasts [nTPM]":"64.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"96.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"189.8","Single Cell Type RNA - granulocytes [nTPM]":"99.3","Single Cell Type RNA - Granulosa cells [nTPM]":"70.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"34.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.8","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"146.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.9","Single Cell Type RNA - Ionocytes [nTPM]":"91.6","Single Cell Type RNA - Kupffer cells [nTPM]":"55.1","Single Cell Type RNA - Langerhans cells [nTPM]":"297.4","Single Cell Type RNA - Late spermatids [nTPM]":"39.2","Single Cell Type RNA - Leydig cells [nTPM]":"34.8","Single Cell Type RNA - Macrophages [nTPM]":"89.5","Single Cell Type RNA - Melanocytes [nTPM]":"96.0","Single Cell Type RNA - Microglial cells [nTPM]":"119.9","Single Cell Type RNA - monocytes [nTPM]":"50.7","Single Cell Type RNA - Muller glia cells [nTPM]":"34.2","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"140.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"155.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.2","Single Cell Type RNA - Paneth cells [nTPM]":"61.6","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"133.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"110.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"39.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"93.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"82.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"52.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"64.4","Single Cell Type RNA - Spermatocytes [nTPM]":"15.3","Single Cell Type RNA - Spermatogonia [nTPM]":"14.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"125.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"180.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"60.5","Single Cell Type RNA - T-cells [nTPM]":"153.2","Single Cell Type RNA - Theca cells [nTPM]":"42.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.5","Single Cell Type RNA - Urothelial cells [nTPM]":"143.6"},{"Gene":"CHM","Gene synonym":["DXS540","REP-1","TCD"],"Ensembl":"ENSG00000188419","Gene description":"CHM Rab escort protein","Uniprot":["P24386"],"Chromosome":"X","Position":"85861180-86047561","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["GTPase activation"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"94.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003231","CAB016171"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016171":"AB_2229397","HPA003231":"AB_1078518"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"7.7","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"7.2","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"12.1","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"7.0","Tissue RNA - lymph node [nTPM]":"7.1","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"5.9","Tissue RNA - parathyroid gland [nTPM]":"14.2","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"9.5","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"7.6","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"9.3","Tissue RNA - salivary gland [nTPM]":"5.6","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"6.4","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"7.3","Tissue RNA - testis [nTPM]":"4.6","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"8.5","Tissue RNA - thyroid gland [nTPM]":"10.9","Tissue RNA - tongue [nTPM]":"10.5","Tissue RNA - tonsil [nTPM]":"6.3","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"16.8","Cell RNA - A549 [nTPM]":"10.9","Cell RNA - AF22 [nTPM]":"10.9","Cell RNA - AN3-CA [nTPM]":"7.2","Cell RNA - ASC diff [nTPM]":"17.4","Cell RNA - ASC TERT1 [nTPM]":"18.4","Cell RNA - BEWO [nTPM]":"6.9","Cell RNA - BJ [nTPM]":"19.3","Cell RNA - BJ hTERT+ [nTPM]":"16.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.4","Cell RNA - CACO-2 [nTPM]":"8.8","Cell RNA - CAPAN-2 [nTPM]":"15.0","Cell RNA - Daudi [nTPM]":"5.7","Cell RNA - EFO-21 [nTPM]":"24.3","Cell RNA - fHDF\/TERT166 [nTPM]":"14.0","Cell RNA - GAMG [nTPM]":"46.1","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"23.9","Cell RNA - HBEC3-KT [nTPM]":"10.9","Cell RNA - HBF TERT88 [nTPM]":"22.5","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"11.4","Cell RNA - HEL [nTPM]":"3.4","Cell RNA - HeLa [nTPM]":"14.6","Cell RNA - Hep G2 [nTPM]":"8.4","Cell RNA - HHSteC [nTPM]":"13.8","Cell RNA - HL-60 [nTPM]":"14.3","Cell RNA - HMC-1 [nTPM]":"23.8","Cell RNA - HSkMC [nTPM]":"14.1","Cell RNA - hTCEpi [nTPM]":"10.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.4","Cell RNA - hTERT-HME1 [nTPM]":"26.9","Cell RNA - hTERT-RPE1 [nTPM]":"14.6","Cell RNA - HUVEC TERT2 [nTPM]":"22.9","Cell RNA - JURKAT [nTPM]":"9.4","Cell RNA - K-562 [nTPM]":"11.9","Cell RNA - Karpas-707 [nTPM]":"19.0","Cell RNA - LHCN-M2 [nTPM]":"20.7","Cell RNA - MCF7 [nTPM]":"4.8","Cell RNA - MOLT-4 [nTPM]":"8.8","Cell RNA - NB-4 [nTPM]":"5.2","Cell RNA - NTERA-2 [nTPM]":"16.2","Cell RNA - OE19 [nTPM]":"11.6","Cell RNA - PC-3 [nTPM]":"17.5","Cell RNA - REH [nTPM]":"9.0","Cell RNA - RH-30 [nTPM]":"19.5","Cell RNA - RPMI-8226 [nTPM]":"8.8","Cell RNA - RPTEC TERT1 [nTPM]":"12.2","Cell RNA - RT4 [nTPM]":"9.5","Cell RNA - SCLC-21H [nTPM]":"9.6","Cell RNA - SH-SY5Y [nTPM]":"14.8","Cell RNA - SiHa [nTPM]":"23.3","Cell RNA - SK-BR-3 [nTPM]":"7.1","Cell RNA - SK-MEL-30 [nTPM]":"18.3","Cell RNA - SuSa [nTPM]":"14.9","Cell RNA - T-47d [nTPM]":"6.0","Cell RNA - THP-1 [nTPM]":"6.7","Cell RNA - TIME [nTPM]":"16.4","Cell RNA - U-138 MG [nTPM]":"16.7","Cell RNA - U-2 OS [nTPM]":"11.0","Cell RNA - U-2197 [nTPM]":"59.0","Cell RNA - U-251 MG [nTPM]":"9.7","Cell RNA - U-266\/70 [nTPM]":"7.2","Cell RNA - U-266\/84 [nTPM]":"27.7","Cell RNA - U-698 [nTPM]":"7.9","Cell RNA - U-87 MG [nTPM]":"18.0","Cell RNA - U-937 [nTPM]":"11.9","Cell RNA - WM-115 [nTPM]":"14.9","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"34.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.0","Single Cell Type RNA - Astrocytes [nTPM]":"33.6","Single Cell Type RNA - B-cells [nTPM]":"22.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"35.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"15.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - dendritic cells [nTPM]":"26.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"16.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.5","Single Cell Type RNA - Endothelial cells [nTPM]":"22.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.7","Single Cell Type RNA - Erythroid cells [nTPM]":"12.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"82.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.6","Single Cell Type RNA - Fibroblasts [nTPM]":"21.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.4","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"18.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"12.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.5","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"94.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.0","Single Cell Type RNA - Langerhans cells [nTPM]":"9.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"21.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"52.5","Single Cell Type RNA - monocytes [nTPM]":"19.6","Single Cell Type RNA - Muller glia cells [nTPM]":"27.5","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"76.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.7","Single Cell Type RNA - Paneth cells [nTPM]":"11.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"17.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"12.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - T-cells [nTPM]":"22.1","Single Cell Type RNA - Theca cells [nTPM]":"28.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.4","Single Cell Type RNA - Urothelial cells [nTPM]":"15.6"},{"Gene":"CHMP2B","Gene synonym":["CHMP2.5","DKFZP564O123","VPS2B"],"Ensembl":"ENSG00000083937","Gene description":"Charged multivesicular body protein 2B","Uniprot":["Q9UQN3"],"Chromosome":"3","Position":"87227271-87255556","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"445.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035069","HPA052754"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035069":"AB_10602798","HPA052754":"AB_2681936"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.11e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.74e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.0","Tissue RNA - adrenal gland [nTPM]":"24.2","Tissue RNA - amygdala [nTPM]":"15.7","Tissue RNA - appendix [nTPM]":"22.8","Tissue RNA - basal ganglia [nTPM]":"20.2","Tissue RNA - bone marrow [nTPM]":"42.7","Tissue RNA - breast [nTPM]":"26.3","Tissue RNA - cerebellum [nTPM]":"22.3","Tissue RNA - cerebral cortex [nTPM]":"22.2","Tissue RNA - cervix [nTPM]":"28.9","Tissue RNA - choroid plexus [nTPM]":"16.2","Tissue RNA - colon [nTPM]":"41.6","Tissue RNA - duodenum [nTPM]":"38.5","Tissue RNA - endometrium 1 [nTPM]":"29.5","Tissue RNA - epididymis [nTPM]":"22.5","Tissue RNA - esophagus [nTPM]":"35.2","Tissue RNA - fallopian tube [nTPM]":"22.6","Tissue RNA - gallbladder [nTPM]":"28.8","Tissue RNA - heart muscle [nTPM]":"27.0","Tissue RNA - hippocampal formation [nTPM]":"15.1","Tissue RNA - hypothalamus [nTPM]":"18.2","Tissue RNA - kidney [nTPM]":"29.6","Tissue RNA - liver [nTPM]":"34.5","Tissue RNA - lung [nTPM]":"22.9","Tissue RNA - lymph node [nTPM]":"21.9","Tissue RNA - medulla oblongata [nTPM]":"25.1","Tissue RNA - midbrain [nTPM]":"21.0","Tissue RNA - ovary [nTPM]":"24.9","Tissue RNA - pancreas [nTPM]":"29.2","Tissue RNA - parathyroid gland [nTPM]":"24.3","Tissue RNA - pituitary gland [nTPM]":"30.4","Tissue RNA - placenta [nTPM]":"25.0","Tissue RNA - pons [nTPM]":"24.1","Tissue RNA - prostate [nTPM]":"34.9","Tissue RNA - rectum [nTPM]":"37.5","Tissue RNA - retina [nTPM]":"15.3","Tissue RNA - salivary gland [nTPM]":"24.9","Tissue RNA - seminal vesicle [nTPM]":"27.7","Tissue RNA - skeletal muscle [nTPM]":"35.3","Tissue RNA - skin 1 [nTPM]":"26.4","Tissue RNA - small intestine [nTPM]":"40.8","Tissue RNA - smooth muscle [nTPM]":"29.6","Tissue RNA - spinal cord [nTPM]":"23.7","Tissue RNA - spleen [nTPM]":"22.1","Tissue RNA - stomach 1 [nTPM]":"31.1","Tissue RNA - testis [nTPM]":"16.1","Tissue RNA - thalamus [nTPM]":"20.3","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"43.1","Tissue RNA - tongue [nTPM]":"28.0","Tissue RNA - tonsil [nTPM]":"21.6","Tissue RNA - urinary bladder [nTPM]":"42.3","Tissue RNA - vagina [nTPM]":"29.7","Tissue RNA - white matter [nTPM]":"31.2","Cell RNA - A-431 [nTPM]":"68.4","Cell RNA - A549 [nTPM]":"71.6","Cell RNA - AF22 [nTPM]":"25.4","Cell RNA - AN3-CA [nTPM]":"17.4","Cell RNA - ASC diff [nTPM]":"45.0","Cell RNA - ASC TERT1 [nTPM]":"38.4","Cell RNA - BEWO [nTPM]":"29.7","Cell RNA - BJ [nTPM]":"52.8","Cell RNA - BJ hTERT+ [nTPM]":"71.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"57.1","Cell RNA - CACO-2 [nTPM]":"57.0","Cell RNA - CAPAN-2 [nTPM]":"115.0","Cell RNA - Daudi [nTPM]":"25.3","Cell RNA - EFO-21 [nTPM]":"36.7","Cell RNA - fHDF\/TERT166 [nTPM]":"60.1","Cell RNA - GAMG [nTPM]":"38.6","Cell RNA - HaCaT [nTPM]":"35.0","Cell RNA - HAP1 [nTPM]":"31.6","Cell RNA - HBEC3-KT [nTPM]":"37.6","Cell RNA - HBF TERT88 [nTPM]":"56.0","Cell RNA - HDLM-2 [nTPM]":"41.7","Cell RNA - HEK 293 [nTPM]":"34.7","Cell RNA - HEL [nTPM]":"29.5","Cell RNA - HeLa [nTPM]":"24.6","Cell RNA - Hep G2 [nTPM]":"25.4","Cell RNA - HHSteC [nTPM]":"39.2","Cell RNA - HL-60 [nTPM]":"44.9","Cell RNA - HMC-1 [nTPM]":"42.5","Cell RNA - HSkMC [nTPM]":"29.3","Cell RNA - hTCEpi [nTPM]":"63.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.9","Cell RNA - hTERT-HME1 [nTPM]":"58.3","Cell RNA - hTERT-RPE1 [nTPM]":"42.6","Cell RNA - HUVEC TERT2 [nTPM]":"35.8","Cell RNA - JURKAT [nTPM]":"29.6","Cell RNA - K-562 [nTPM]":"17.3","Cell RNA - Karpas-707 [nTPM]":"36.7","Cell RNA - LHCN-M2 [nTPM]":"50.2","Cell RNA - MCF7 [nTPM]":"53.2","Cell RNA - MOLT-4 [nTPM]":"41.1","Cell RNA - NB-4 [nTPM]":"18.3","Cell RNA - NTERA-2 [nTPM]":"32.4","Cell RNA - OE19 [nTPM]":"91.1","Cell RNA - PC-3 [nTPM]":"65.5","Cell RNA - REH [nTPM]":"21.4","Cell RNA - RH-30 [nTPM]":"31.0","Cell RNA - RPMI-8226 [nTPM]":"26.1","Cell RNA - RPTEC TERT1 [nTPM]":"36.0","Cell RNA - RT4 [nTPM]":"71.3","Cell RNA - SCLC-21H [nTPM]":"9.7","Cell RNA - SH-SY5Y [nTPM]":"10.8","Cell RNA - SiHa [nTPM]":"54.2","Cell RNA - SK-BR-3 [nTPM]":"45.6","Cell RNA - SK-MEL-30 [nTPM]":"91.4","Cell RNA - SuSa [nTPM]":"28.8","Cell RNA - T-47d [nTPM]":"40.6","Cell RNA - THP-1 [nTPM]":"13.7","Cell RNA - TIME [nTPM]":"30.6","Cell RNA - U-138 MG [nTPM]":"42.9","Cell RNA - U-2 OS [nTPM]":"36.5","Cell RNA - U-2197 [nTPM]":"445.0","Cell RNA - U-251 MG [nTPM]":"37.7","Cell RNA - U-266\/70 [nTPM]":"37.7","Cell RNA - U-266\/84 [nTPM]":"56.3","Cell RNA - U-698 [nTPM]":"41.6","Cell RNA - U-87 MG [nTPM]":"47.6","Cell RNA - U-937 [nTPM]":"24.8","Cell RNA - WM-115 [nTPM]":"30.9","Blood RNA - basophil [nTPM]":"124.7","Blood RNA - classical monocyte [nTPM]":"50.7","Blood RNA - eosinophil [nTPM]":"136.7","Blood RNA - gdT-cell [nTPM]":"27.3","Blood RNA - intermediate monocyte [nTPM]":"65.2","Blood RNA - MAIT T-cell [nTPM]":"37.3","Blood RNA - memory B-cell [nTPM]":"49.6","Blood RNA - memory CD4 T-cell [nTPM]":"34.6","Blood RNA - memory CD8 T-cell [nTPM]":"34.8","Blood RNA - myeloid DC [nTPM]":"55.1","Blood RNA - naive B-cell [nTPM]":"53.4","Blood RNA - naive CD4 T-cell [nTPM]":"32.0","Blood RNA - naive CD8 T-cell [nTPM]":"32.4","Blood RNA - neutrophil [nTPM]":"96.8","Blood RNA - NK-cell [nTPM]":"31.4","Blood RNA - non-classical monocyte [nTPM]":"67.8","Blood RNA - plasmacytoid DC [nTPM]":"31.3","Blood RNA - T-reg [nTPM]":"52.4","Blood RNA - total PBMC [nTPM]":"37.8","Brain RNA - amygdala [nTPM]":"15.7","Brain RNA - basal ganglia [nTPM]":"20.2","Brain RNA - cerebellum [nTPM]":"22.3","Brain RNA - cerebral cortex [nTPM]":"22.2","Brain RNA - hippocampal formation [nTPM]":"15.1","Brain RNA - hypothalamus [nTPM]":"18.2","Brain RNA - medulla oblongata [nTPM]":"25.1","Brain RNA - midbrain [nTPM]":"21.0","Brain RNA - pons [nTPM]":"24.1","Brain RNA - spinal cord [nTPM]":"23.7","Brain RNA - thalamus [nTPM]":"20.3","Brain RNA - white matter [nTPM]":"31.2","Single Cell Type RNA - Adipocytes [nTPM]":"56.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"68.7","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"58.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"132.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"254.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"90.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"53.5","Single Cell Type RNA - Bipolar cells [nTPM]":"19.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"52.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"68.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"62.9","Single Cell Type RNA - Club cells [nTPM]":"85.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"75.4","Single Cell Type RNA - dendritic cells [nTPM]":"45.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"268.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"138.9","Single Cell Type RNA - Ductal cells [nTPM]":"170.6","Single Cell Type RNA - Early spermatids [nTPM]":"6.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"86.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"45.2","Single Cell Type RNA - Endothelial cells [nTPM]":"54.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.7","Single Cell Type RNA - Erythroid cells [nTPM]":"36.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"261.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"187.0","Single Cell Type RNA - Fibroblasts [nTPM]":"68.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"48.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"86.9","Single Cell Type RNA - granulocytes [nTPM]":"74.1","Single Cell Type RNA - Granulosa cells [nTPM]":"27.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.5","Single Cell Type RNA - Hepatocytes [nTPM]":"60.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"86.9","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"80.3","Single Cell Type RNA - Ionocytes [nTPM]":"73.2","Single Cell Type RNA - Kupffer cells [nTPM]":"61.9","Single Cell Type RNA - Langerhans cells [nTPM]":"87.6","Single Cell Type RNA - Late spermatids [nTPM]":"7.5","Single Cell Type RNA - Leydig cells [nTPM]":"66.2","Single Cell Type RNA - Macrophages [nTPM]":"72.6","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"62.0","Single Cell Type RNA - Muller glia cells [nTPM]":"213.9","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"237.4","Single Cell Type RNA - Paneth cells [nTPM]":"241.3","Single Cell Type RNA - Peritubular cells [nTPM]":"96.3","Single Cell Type RNA - Plasma cells [nTPM]":"30.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"226.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"101.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"145.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"90.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"58.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"57.5","Single Cell Type RNA - Spermatocytes [nTPM]":"78.7","Single Cell Type RNA - Spermatogonia [nTPM]":"76.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"62.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"145.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"180.9","Single Cell Type RNA - T-cells [nTPM]":"52.9","Single Cell Type RNA - Theca cells [nTPM]":"38.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"81.3","Single Cell Type RNA - Urothelial cells [nTPM]":"330.3"},{"Gene":"CHMP4B","Gene synonym":["C20orf178","dJ553F4.4","Shax1","SNF7-2","VPS32B"],"Ensembl":"ENSG00000101421","Gene description":"Charged multivesicular body protein 4B","Uniprot":["Q9H444"],"Chromosome":"20","Position":"33811348-33854366","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041401","HPA051751"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"53000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041401":"AB_10965028","HPA051751":"AB_2681591"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.10e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"105.8","Tissue RNA - adrenal gland [nTPM]":"112.3","Tissue RNA - amygdala [nTPM]":"93.3","Tissue RNA - appendix [nTPM]":"75.8","Tissue RNA - basal ganglia [nTPM]":"95.3","Tissue RNA - bone marrow [nTPM]":"213.7","Tissue RNA - breast [nTPM]":"102.2","Tissue RNA - cerebellum [nTPM]":"93.9","Tissue RNA - cerebral cortex [nTPM]":"112.3","Tissue RNA - cervix [nTPM]":"112.9","Tissue RNA - choroid plexus [nTPM]":"82.5","Tissue RNA - colon [nTPM]":"155.1","Tissue RNA - duodenum [nTPM]":"103.0","Tissue RNA - endometrium 1 [nTPM]":"107.8","Tissue RNA - epididymis [nTPM]":"58.6","Tissue RNA - esophagus [nTPM]":"159.0","Tissue RNA - fallopian tube [nTPM]":"84.4","Tissue RNA - gallbladder [nTPM]":"80.6","Tissue RNA - heart muscle [nTPM]":"147.1","Tissue RNA - hippocampal formation [nTPM]":"98.4","Tissue RNA - hypothalamus [nTPM]":"98.9","Tissue RNA - kidney [nTPM]":"122.9","Tissue RNA - liver [nTPM]":"67.7","Tissue RNA - lung [nTPM]":"101.5","Tissue RNA - lymph node [nTPM]":"70.7","Tissue RNA - medulla oblongata [nTPM]":"97.7","Tissue RNA - midbrain [nTPM]":"94.5","Tissue RNA - ovary [nTPM]":"94.9","Tissue RNA - pancreas [nTPM]":"82.1","Tissue RNA - parathyroid gland [nTPM]":"74.8","Tissue RNA - pituitary gland [nTPM]":"74.6","Tissue RNA - placenta [nTPM]":"74.7","Tissue RNA - pons [nTPM]":"95.6","Tissue RNA - prostate [nTPM]":"90.4","Tissue RNA - rectum [nTPM]":"98.7","Tissue RNA - retina [nTPM]":"53.3","Tissue RNA - salivary gland [nTPM]":"118.1","Tissue RNA - seminal vesicle [nTPM]":"82.4","Tissue RNA - skeletal muscle [nTPM]":"231.3","Tissue RNA - skin 1 [nTPM]":"120.9","Tissue RNA - small intestine [nTPM]":"119.9","Tissue RNA - smooth muscle [nTPM]":"76.3","Tissue RNA - spinal cord [nTPM]":"93.7","Tissue RNA - spleen [nTPM]":"83.0","Tissue RNA - stomach 1 [nTPM]":"117.3","Tissue RNA - testis [nTPM]":"60.2","Tissue RNA - thalamus [nTPM]":"97.5","Tissue RNA - thymus [nTPM]":"82.8","Tissue RNA - thyroid gland [nTPM]":"88.4","Tissue RNA - tongue [nTPM]":"132.6","Tissue RNA - tonsil [nTPM]":"71.2","Tissue RNA - urinary bladder [nTPM]":"132.0","Tissue RNA - vagina [nTPM]":"106.9","Tissue RNA - white matter [nTPM]":"99.4","Cell RNA - A-431 [nTPM]":"206.4","Cell RNA - A549 [nTPM]":"131.3","Cell RNA - AF22 [nTPM]":"72.3","Cell RNA - AN3-CA [nTPM]":"69.3","Cell RNA - ASC diff [nTPM]":"118.8","Cell RNA - ASC TERT1 [nTPM]":"95.2","Cell RNA - BEWO [nTPM]":"114.5","Cell RNA - BJ [nTPM]":"120.4","Cell RNA - BJ hTERT+ [nTPM]":"159.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"126.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"117.5","Cell RNA - CACO-2 [nTPM]":"279.1","Cell RNA - CAPAN-2 [nTPM]":"171.2","Cell RNA - Daudi [nTPM]":"98.1","Cell RNA - EFO-21 [nTPM]":"183.3","Cell RNA - fHDF\/TERT166 [nTPM]":"122.3","Cell RNA - GAMG [nTPM]":"192.0","Cell RNA - HaCaT [nTPM]":"160.8","Cell RNA - HAP1 [nTPM]":"83.2","Cell RNA - HBEC3-KT [nTPM]":"182.3","Cell RNA - HBF TERT88 [nTPM]":"99.2","Cell RNA - HDLM-2 [nTPM]":"51.0","Cell RNA - HEK 293 [nTPM]":"89.3","Cell RNA - HEL [nTPM]":"174.1","Cell RNA - HeLa [nTPM]":"90.4","Cell RNA - Hep G2 [nTPM]":"189.3","Cell RNA - HHSteC [nTPM]":"137.5","Cell RNA - HL-60 [nTPM]":"86.1","Cell RNA - HMC-1 [nTPM]":"88.1","Cell RNA - HSkMC [nTPM]":"137.2","Cell RNA - hTCEpi [nTPM]":"99.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"116.3","Cell RNA - hTERT-HME1 [nTPM]":"106.6","Cell RNA - hTERT-RPE1 [nTPM]":"125.2","Cell RNA - HUVEC TERT2 [nTPM]":"141.9","Cell RNA - JURKAT [nTPM]":"113.1","Cell RNA - K-562 [nTPM]":"84.2","Cell RNA - Karpas-707 [nTPM]":"139.0","Cell RNA - LHCN-M2 [nTPM]":"97.8","Cell RNA - MCF7 [nTPM]":"130.2","Cell RNA - MOLT-4 [nTPM]":"189.8","Cell RNA - NB-4 [nTPM]":"246.5","Cell RNA - NTERA-2 [nTPM]":"63.4","Cell RNA - OE19 [nTPM]":"226.3","Cell RNA - PC-3 [nTPM]":"179.8","Cell RNA - REH [nTPM]":"97.7","Cell RNA - RH-30 [nTPM]":"147.2","Cell RNA - RPMI-8226 [nTPM]":"120.7","Cell RNA - RPTEC TERT1 [nTPM]":"142.7","Cell RNA - RT4 [nTPM]":"234.0","Cell RNA - SCLC-21H [nTPM]":"56.4","Cell RNA - SH-SY5Y [nTPM]":"68.6","Cell RNA - SiHa [nTPM]":"225.0","Cell RNA - SK-BR-3 [nTPM]":"192.2","Cell RNA - SK-MEL-30 [nTPM]":"165.8","Cell RNA - SuSa [nTPM]":"85.1","Cell RNA - T-47d [nTPM]":"149.0","Cell RNA - THP-1 [nTPM]":"123.9","Cell RNA - TIME [nTPM]":"129.9","Cell RNA - U-138 MG [nTPM]":"216.8","Cell RNA - U-2 OS [nTPM]":"85.0","Cell RNA - U-2197 [nTPM]":"108.7","Cell RNA - U-251 MG [nTPM]":"117.9","Cell RNA - U-266\/70 [nTPM]":"132.4","Cell RNA - U-266\/84 [nTPM]":"101.3","Cell RNA - U-698 [nTPM]":"117.0","Cell RNA - U-87 MG [nTPM]":"176.5","Cell RNA - U-937 [nTPM]":"91.6","Cell RNA - WM-115 [nTPM]":"65.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"93.3","Brain RNA - basal ganglia [nTPM]":"95.3","Brain RNA - cerebellum [nTPM]":"93.9","Brain RNA - cerebral cortex [nTPM]":"112.3","Brain RNA - hippocampal formation [nTPM]":"98.4","Brain RNA - hypothalamus [nTPM]":"98.9","Brain RNA - medulla oblongata [nTPM]":"97.7","Brain RNA - midbrain [nTPM]":"94.5","Brain RNA - pons [nTPM]":"95.6","Brain RNA - spinal cord [nTPM]":"93.7","Brain RNA - thalamus [nTPM]":"97.5","Brain RNA - white matter [nTPM]":"99.4","Single Cell Type RNA - Adipocytes [nTPM]":"66.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.6","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"71.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"298.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"224.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"133.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"113.3","Single Cell Type RNA - Bipolar cells [nTPM]":"22.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"149.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"64.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"95.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"112.9","Single Cell Type RNA - Club cells [nTPM]":"148.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"110.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"197.7","Single Cell Type RNA - dendritic cells [nTPM]":"77.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"565.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"144.8","Single Cell Type RNA - Ductal cells [nTPM]":"360.9","Single Cell Type RNA - Early spermatids [nTPM]":"17.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"81.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"76.1","Single Cell Type RNA - Endothelial cells [nTPM]":"126.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"127.4","Single Cell Type RNA - Erythroid cells [nTPM]":"81.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"497.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"151.2","Single Cell Type RNA - Fibroblasts [nTPM]":"130.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"112.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"130.6","Single Cell Type RNA - granulocytes [nTPM]":"28.5","Single Cell Type RNA - Granulosa cells [nTPM]":"22.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"71.7","Single Cell Type RNA - Hepatocytes [nTPM]":"69.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"215.3","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"212.7","Single Cell Type RNA - Ionocytes [nTPM]":"154.6","Single Cell Type RNA - Kupffer cells [nTPM]":"119.3","Single Cell Type RNA - Langerhans cells [nTPM]":"383.6","Single Cell Type RNA - Late spermatids [nTPM]":"18.8","Single Cell Type RNA - Leydig cells [nTPM]":"93.8","Single Cell Type RNA - Macrophages [nTPM]":"140.2","Single Cell Type RNA - Melanocytes [nTPM]":"220.5","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"289.8","Single Cell Type RNA - Muller glia cells [nTPM]":"73.6","Single Cell Type RNA - NK-cells [nTPM]":"46.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"540.2","Single Cell Type RNA - Paneth cells [nTPM]":"536.6","Single Cell Type RNA - Peritubular cells [nTPM]":"120.7","Single Cell Type RNA - Plasma cells [nTPM]":"139.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"426.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"482.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"180.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"101.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"79.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"120.5","Single Cell Type RNA - Spermatocytes [nTPM]":"24.5","Single Cell Type RNA - Spermatogonia [nTPM]":"29.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"291.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"341.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"440.3","Single Cell Type RNA - T-cells [nTPM]":"62.9","Single Cell Type RNA - Theca cells [nTPM]":"35.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"227.4","Single Cell Type RNA - Urothelial cells [nTPM]":"413.2"},{"Gene":"CHN1","Gene synonym":["ARHGAP2","CHN","DURS2","n-chimerin","RhoGAP2"],"Ensembl":"ENSG00000128656","Gene description":"Chimerin 1","Uniprot":["P15882"],"Chromosome":"2","Position":"174798809-175005381","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Neurogenesis"],"Molecular function":["GTPase activation"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"772.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"195.2","Excitatory neurons":"596.4","Inhibitory neurons":"111.7","Microglial cells":"97.4","Oligodendrocyte precursor cells":"149.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"18.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory CD4 T-cell":"6.5","memory CD8 T-cell":"2.1","T-reg":"8.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"T-cells":"8.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"186.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036111"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036111":"AB_10671241"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"13.3","Tissue RNA - amygdala [nTPM]":"368.6","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"445.9","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"10.5","Tissue RNA - cerebellum [nTPM]":"194.0","Tissue RNA - cerebral cortex [nTPM]":"772.6","Tissue RNA - cervix [nTPM]":"9.2","Tissue RNA - choroid plexus [nTPM]":"170.6","Tissue RNA - colon [nTPM]":"10.2","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"7.9","Tissue RNA - epididymis [nTPM]":"38.3","Tissue RNA - esophagus [nTPM]":"6.9","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"11.1","Tissue RNA - heart muscle [nTPM]":"15.1","Tissue RNA - hippocampal formation [nTPM]":"492.6","Tissue RNA - hypothalamus [nTPM]":"241.5","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"19.6","Tissue RNA - lymph node [nTPM]":"21.5","Tissue RNA - medulla oblongata [nTPM]":"210.2","Tissue RNA - midbrain [nTPM]":"225.4","Tissue RNA - ovary [nTPM]":"5.8","Tissue RNA - pancreas [nTPM]":"4.2","Tissue RNA - parathyroid gland [nTPM]":"43.4","Tissue RNA - pituitary gland [nTPM]":"36.3","Tissue RNA - placenta [nTPM]":"38.6","Tissue RNA - pons [nTPM]":"210.5","Tissue RNA - prostate [nTPM]":"17.0","Tissue RNA - rectum [nTPM]":"5.1","Tissue RNA - retina [nTPM]":"39.5","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"9.6","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"13.1","Tissue RNA - spinal cord [nTPM]":"192.4","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"7.1","Tissue RNA - testis [nTPM]":"21.3","Tissue RNA - thalamus [nTPM]":"239.1","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"18.7","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"422.8","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"17.4","Cell RNA - AF22 [nTPM]":"57.6","Cell RNA - AN3-CA [nTPM]":"16.3","Cell RNA - ASC diff [nTPM]":"14.7","Cell RNA - ASC TERT1 [nTPM]":"67.4","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"45.6","Cell RNA - BJ hTERT+ [nTPM]":"186.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"97.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"5.4","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"71.8","Cell RNA - GAMG [nTPM]":"39.9","Cell RNA - HaCaT [nTPM]":"2.0","Cell RNA - HAP1 [nTPM]":"68.0","Cell RNA - HBEC3-KT [nTPM]":"1.9","Cell RNA - HBF TERT88 [nTPM]":"30.3","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"32.9","Cell RNA - HEL [nTPM]":"11.1","Cell RNA - HeLa [nTPM]":"20.1","Cell RNA - Hep G2 [nTPM]":"3.8","Cell RNA - HHSteC [nTPM]":"34.4","Cell RNA - HL-60 [nTPM]":"6.4","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"53.6","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.6","Cell RNA - hTERT-HME1 [nTPM]":"11.1","Cell RNA - hTERT-RPE1 [nTPM]":"16.1","Cell RNA - HUVEC TERT2 [nTPM]":"33.6","Cell RNA - JURKAT [nTPM]":"30.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"1.9","Cell RNA - LHCN-M2 [nTPM]":"57.2","Cell RNA - MCF7 [nTPM]":"11.8","Cell RNA - MOLT-4 [nTPM]":"29.3","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"71.7","Cell RNA - OE19 [nTPM]":"2.6","Cell RNA - PC-3 [nTPM]":"23.7","Cell RNA - REH [nTPM]":"8.2","Cell RNA - RH-30 [nTPM]":"70.3","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"71.3","Cell RNA - SH-SY5Y [nTPM]":"76.3","Cell RNA - SiHa [nTPM]":"41.3","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"7.3","Cell RNA - SuSa [nTPM]":"36.0","Cell RNA - T-47d [nTPM]":"3.2","Cell RNA - THP-1 [nTPM]":"2.2","Cell RNA - TIME [nTPM]":"10.1","Cell RNA - U-138 MG [nTPM]":"26.8","Cell RNA - U-2 OS [nTPM]":"3.9","Cell RNA - U-2197 [nTPM]":"9.8","Cell RNA - U-251 MG [nTPM]":"20.6","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"33.7","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"6.7","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"6.6","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"6.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"8.0","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"368.6","Brain RNA - basal ganglia [nTPM]":"445.9","Brain RNA - cerebellum [nTPM]":"194.0","Brain RNA - cerebral cortex [nTPM]":"772.6","Brain RNA - hippocampal formation [nTPM]":"492.6","Brain RNA - hypothalamus [nTPM]":"241.5","Brain RNA - medulla oblongata [nTPM]":"210.2","Brain RNA - midbrain [nTPM]":"225.4","Brain RNA - pons [nTPM]":"210.5","Brain RNA - spinal cord [nTPM]":"192.4","Brain RNA - thalamus [nTPM]":"239.1","Brain RNA - white matter [nTPM]":"422.8","Single Cell Type RNA - Adipocytes [nTPM]":"15.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.9","Single Cell Type RNA - Astrocytes [nTPM]":"195.2","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"85.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"24.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.6","Single Cell Type RNA - Endothelial cells [nTPM]":"17.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"596.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"28.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.7","Single Cell Type RNA - Horizontal cells [nTPM]":"77.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"111.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"23.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"97.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"59.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"149.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"88.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.3","Single Cell Type RNA - Spermatocytes [nTPM]":"17.8","Single Cell Type RNA - Spermatogonia [nTPM]":"23.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"12.5","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"CHRDL1","Gene synonym":["CHL","MGC1","NRLN1"],"Ensembl":"ENSG00000101938","Gene description":"Chordin like 1","Uniprot":["Q9BU40"],"Chromosome":"X","Position":"110673856-110795819","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Differentiation","Neurogenesis","Osteogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"seminal vesicle":"224.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"50.3","Fibroblasts":"83.8","Leydig cells":"41.0","Muller glia cells":"81.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"16.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"ASC diff":"537.8","ASC TERT1":"724.7","hTERT-RPE1":"341.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000226","HPA000250"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"610000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000226":"AB_1078522","HPA000250":"AB_1078521"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.23e-4"},"Tissue RNA - adipose tissue [nTPM]":"188.3","Tissue RNA - adrenal gland [nTPM]":"7.3","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"26.2","Tissue RNA - basal ganglia [nTPM]":"14.5","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"69.8","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"14.1","Tissue RNA - cervix [nTPM]":"38.8","Tissue RNA - choroid plexus [nTPM]":"6.5","Tissue RNA - colon [nTPM]":"74.8","Tissue RNA - duodenum [nTPM]":"10.8","Tissue RNA - endometrium 1 [nTPM]":"148.2","Tissue RNA - epididymis [nTPM]":"20.2","Tissue RNA - esophagus [nTPM]":"58.0","Tissue RNA - fallopian tube [nTPM]":"53.5","Tissue RNA - gallbladder [nTPM]":"47.9","Tissue RNA - heart muscle [nTPM]":"22.0","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"15.1","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"76.3","Tissue RNA - lymph node [nTPM]":"24.4","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"12.5","Tissue RNA - parathyroid gland [nTPM]":"84.9","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"21.9","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"141.6","Tissue RNA - rectum [nTPM]":"35.5","Tissue RNA - retina [nTPM]":"55.6","Tissue RNA - salivary gland [nTPM]":"23.3","Tissue RNA - seminal vesicle [nTPM]":"224.4","Tissue RNA - skeletal muscle [nTPM]":"6.1","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"22.1","Tissue RNA - smooth muscle [nTPM]":"101.3","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"16.0","Tissue RNA - stomach 1 [nTPM]":"17.9","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"5.8","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"37.8","Tissue RNA - tongue [nTPM]":"34.9","Tissue RNA - tonsil [nTPM]":"11.7","Tissue RNA - urinary bladder [nTPM]":"28.3","Tissue RNA - vagina [nTPM]":"20.0","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"3.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"537.8","Cell RNA - ASC TERT1 [nTPM]":"724.7","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"7.6","Cell RNA - BJ hTERT+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"23.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"17.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"58.7","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"341.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"21.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"5.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"5.8","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"60.4","Cell RNA - U-251 MG [nTPM]":"7.8","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"14.5","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"14.1","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"5.8","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"50.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"13.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"83.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"8.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"41.0","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"81.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"8.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CHRNA1","Gene synonym":["CHRNA"],"Ensembl":"ENSG00000138435","Gene description":"Cholinergic receptor nicotinic alpha 1 subunit","Uniprot":["P02708"],"Chromosome":"2","Position":"174747592-174787935","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"skeletal muscle":"170.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"48","RNA single cell type specific nTPM":{"Skeletal myocytes":"193.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.8"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"13","RNA brain regional specific nTPM":{"cerebral cortex":"12.8","hippocampal formation":"5.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"LHCN-M2":"445.4","RH-30":"360.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071554"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA071554":"AB_2686416"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"1.5","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"5.5","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"170.1","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"20.4","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"21.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"445.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"360.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"2.9","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.8","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"5.5","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"193.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CHRNA2","Gene synonym":[],"Ensembl":"ENSG00000120903","Gene description":"Cholinergic receptor nicotinic alpha 2 subunit","Uniprot":["Q15822"],"Chromosome":"8","Position":"27459756-27479883","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"72.1","prostate":"29.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"6.5","Inhibitory neurons":"14.8","Prostatic glandular cells":"2.4","Theca cells":"3.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"421","RNA cancer specific FPKM":{"prostate cancer":"30.2"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"72.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048348"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytokinetic bridge"],"Antibody RRID":{"HPA048348":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"15.8","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"38.1","Tissue RNA - cerebral cortex [nTPM]":"2.9","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"15.7","Tissue RNA - midbrain [nTPM]":"21.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.5","Tissue RNA - prostate [nTPM]":"29.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"72.1","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"15.8","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"38.1","Brain RNA - cerebral cortex [nTPM]":"2.9","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"15.7","Brain RNA - midbrain [nTPM]":"21.5","Brain RNA - pons [nTPM]":"3.5","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"72.1","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"3.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CHRNA4","Gene synonym":["BFNC","EBN","EBN1"],"Ensembl":"ENSG00000101204","Gene description":"Cholinergic receptor nicotinic alpha 4 subunit","Uniprot":["P43681"],"Chromosome":"20","Position":"63343223-63378401","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.8","liver":"58.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"42.0","Horizontal cells":"139.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"U-2 OS":"2.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"midbrain":"21.8","pons":"20.5","thalamus":"33.5"},"Antibody":["CAB034064"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034064":"AB_2080535"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"6.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"58.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"5.7","Tissue RNA - midbrain [nTPM]":"15.7","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"12.7","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"28.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"6.2","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"5.7","Brain RNA - midbrain [nTPM]":"15.7","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"28.8","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"42.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"139.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CHRNB1","Gene synonym":["CHRNB"],"Ensembl":"ENSG00000170175","Gene description":"Cholinergic receptor nicotinic beta 1 subunit","Uniprot":["P11230"],"Chromosome":"17","Position":"7445061-7457710","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"158.4","tongue":"57.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"39.0","Skeletal myocytes":"47.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"LHCN-M2":"34.6","RH-30":"71.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005822","CAB011200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011200":"AB_262151","HPA005822":"AB_1079484"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.0","Tissue RNA - adrenal gland [nTPM]":"30.6","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"2.4","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"8.8","Tissue RNA - colon [nTPM]":"6.3","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"6.6","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"7.0","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"16.5","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"7.5","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"16.5","Tissue RNA - parathyroid gland [nTPM]":"9.1","Tissue RNA - pituitary gland [nTPM]":"6.7","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"10.7","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"158.4","Tissue RNA - skin 1 [nTPM]":"8.1","Tissue RNA - small intestine [nTPM]":"5.5","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"13.0","Tissue RNA - tongue [nTPM]":"57.7","Tissue RNA - tonsil [nTPM]":"3.9","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"7.2","Tissue RNA - white matter [nTPM]":"8.1","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"2.2","Cell RNA - AF22 [nTPM]":"3.8","Cell RNA - AN3-CA [nTPM]":"4.5","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"4.0","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.6","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"2.0","Cell RNA - Daudi [nTPM]":"6.2","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2.5","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"13.6","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"25.1","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"4.8","Cell RNA - HEL [nTPM]":"3.5","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"8.1","Cell RNA - HHSteC [nTPM]":"2.6","Cell RNA - HL-60 [nTPM]":"2.2","Cell RNA - HMC-1 [nTPM]":"8.6","Cell RNA - HSkMC [nTPM]":"8.8","Cell RNA - hTCEpi [nTPM]":"6.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.4","Cell RNA - hTERT-HME1 [nTPM]":"11.0","Cell RNA - hTERT-RPE1 [nTPM]":"9.3","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"12.0","Cell RNA - K-562 [nTPM]":"4.6","Cell RNA - Karpas-707 [nTPM]":"3.4","Cell RNA - LHCN-M2 [nTPM]":"34.6","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"6.7","Cell RNA - NB-4 [nTPM]":"4.1","Cell RNA - NTERA-2 [nTPM]":"2.7","Cell RNA - OE19 [nTPM]":"1.5","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"4.4","Cell RNA - RH-30 [nTPM]":"71.0","Cell RNA - RPMI-8226 [nTPM]":"15.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"1.2","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"11.1","Cell RNA - SiHa [nTPM]":"2.4","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"4.7","Cell RNA - SuSa [nTPM]":"5.9","Cell RNA - T-47d [nTPM]":"3.9","Cell RNA - THP-1 [nTPM]":"3.0","Cell RNA - TIME [nTPM]":"3.6","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"5.0","Cell RNA - U-266\/70 [nTPM]":"8.1","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"4.9","Cell RNA - WM-115 [nTPM]":"2.1","Blood RNA - basophil [nTPM]":"9.9","Blood RNA - classical monocyte [nTPM]":"5.4","Blood RNA - eosinophil [nTPM]":"13.6","Blood RNA - gdT-cell [nTPM]":"7.9","Blood RNA - intermediate monocyte [nTPM]":"6.3","Blood RNA - MAIT T-cell [nTPM]":"6.1","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"8.7","Blood RNA - memory CD8 T-cell [nTPM]":"8.0","Blood RNA - myeloid DC [nTPM]":"7.0","Blood RNA - naive B-cell [nTPM]":"7.0","Blood RNA - naive CD4 T-cell [nTPM]":"7.0","Blood RNA - naive CD8 T-cell [nTPM]":"9.2","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"10.4","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"7.9","Blood RNA - total PBMC [nTPM]":"6.1","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"7.5","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"8.1","Single Cell Type RNA - Adipocytes [nTPM]":"8.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"8.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.0","Single Cell Type RNA - dendritic cells [nTPM]":"17.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"16.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.4","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.1","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"5.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"10.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"21.8","Single Cell Type RNA - Macrophages [nTPM]":"7.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"17.0","Single Cell Type RNA - Muller glia cells [nTPM]":"14.0","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.3","Single Cell Type RNA - Paneth cells [nTPM]":"4.9","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.4","Single Cell Type RNA - T-cells [nTPM]":"11.2","Single Cell Type RNA - Theca cells [nTPM]":"12.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"CHRNB2","Gene synonym":[],"Ensembl":"ENSG00000160716","Gene description":"Cholinergic receptor nicotinic beta 2 subunit","Uniprot":["P17787"],"Chromosome":"1","Position":"154567778-154580013","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.4","retina":"8.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"12.7","Cone photoreceptor cells":"14.6","Horizontal cells":"42.1","Inhibitory neurons":"7.8","Late spermatids":"11.8","Rod photoreceptor cells":"7.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"SCLC-21H":"25.7","SH-SY5Y":"25.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"6.5","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"7.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"17.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"8.7","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"5.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"2.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.3","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"25.7","Cell RNA - SH-SY5Y [nTPM]":"25.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.5","Brain RNA - basal ganglia [nTPM]":"7.5","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"17.4","Brain RNA - hippocampal formation [nTPM]":"8.7","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"5.5","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"12.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CHRND","Gene synonym":["ACHRD"],"Ensembl":"ENSG00000135902","Gene description":"Cholinergic receptor nicotinic delta subunit","Uniprot":["Q07001"],"Chromosome":"2","Position":"232525993-232536667","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"skeletal muscle":"57.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Muller glia cells":"4.0","Skeletal myocytes":"4.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"head and neck cancer":"1.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"49","RNA cell line specific nTPM":{"RH-30":"99.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056404","HPA065404"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA056404":"AB_2732603","HPA065404":"AB_2732734"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"57.6","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"99.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CHRNE","Gene synonym":["ACHRE"],"Ensembl":"ENSG00000108556","Gene description":"Cholinergic receptor nicotinic epsilon subunit","Uniprot":["Q04844"],"Chromosome":"17","Position":"4897771-4934438","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"heart muscle":"55.3","pituitary gland":"27.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"161.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"2.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"HEL":"5.0","HMC-1":"11.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"14","RNA pig brain regional specific nTPM":{"basal ganglia":"6.3"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"55.3","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"3.5","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"27.6","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"5.1","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"5.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"11.5","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"4.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"27.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"1.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.4","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"13.0","Single Cell Type RNA - Late spermatids [nTPM]":"161.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"9.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"5.3","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"5.6","Single Cell Type RNA - Spermatogonia [nTPM]":"8.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - T-cells [nTPM]":"3.5","Single Cell Type RNA - Theca cells [nTPM]":"6.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"CHST6","Gene synonym":["MCDC1"],"Ensembl":"ENSG00000183196","Gene description":"Carbohydrate sulfotransferase 6","Uniprot":["Q9GZX3"],"Chromosome":"16","Position":"75472052-75495445","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"13.5","cervix":"9.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"60.0","Oligodendrocytes":"17.0","Respiratory ciliated cells":"16.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"9.3","CAPAN-2":"9.9","NTERA-2":"4.8","SK-MEL-30":"4.1","U-2 OS":"5.0","WM-115":"5.4"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068029"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA068029":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"5.4","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"11.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"9.4","Tissue RNA - choroid plexus [nTPM]":"3.4","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"4.5","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"10.7","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"13.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"11.5","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"10.9","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"13.5","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"11.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"9.3","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"9.9","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"4.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"4.1","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"5.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"2.1","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"5.4","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"11.8","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"10.7","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"13.2","Brain RNA - pons [nTPM]":"11.5","Brain RNA - spinal cord [nTPM]":"10.9","Brain RNA - thalamus [nTPM]":"13.5","Brain RNA - white matter [nTPM]":"11.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.4","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"60.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"8.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.9"},{"Gene":"CIB2","Gene synonym":["DFNB48","KIP2","USH1J"],"Ensembl":"ENSG00000136425","Gene description":"Calcium and integrin binding family member 2","Uniprot":["O75838"],"Chromosome":"15","Position":"78104606-78131535","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"47.7","lymphoid tissue":"47.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"73.1","Late spermatids":"269.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"48","RNA blood cell specific nTPM":{"plasmacytoid DC":"18.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"48","RNA blood lineage specific nTPM":{"dendritic cells":"18.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"44.0","GAMG":"39.0","HAP1":"38.6","SCLC-21H":"38.8","SH-SY5Y":"40.1","SuSa":"49.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036697"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036697":"AB_10672475"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.05e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-3"},"Tissue RNA - adipose tissue [nTPM]":"7.0","Tissue RNA - adrenal gland [nTPM]":"12.1","Tissue RNA - amygdala [nTPM]":"16.7","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"16.9","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"15.9","Tissue RNA - cerebral cortex [nTPM]":"22.9","Tissue RNA - cervix [nTPM]":"13.1","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"18.7","Tissue RNA - endometrium 1 [nTPM]":"9.1","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"2.8","Tissue RNA - heart muscle [nTPM]":"47.7","Tissue RNA - hippocampal formation [nTPM]":"18.1","Tissue RNA - hypothalamus [nTPM]":"17.4","Tissue RNA - kidney [nTPM]":"9.1","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"3.0","Tissue RNA - lymph node [nTPM]":"3.5","Tissue RNA - medulla oblongata [nTPM]":"20.1","Tissue RNA - midbrain [nTPM]":"18.3","Tissue RNA - ovary [nTPM]":"7.3","Tissue RNA - pancreas [nTPM]":"5.9","Tissue RNA - parathyroid gland [nTPM]":"13.4","Tissue RNA - pituitary gland [nTPM]":"10.4","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"20.1","Tissue RNA - prostate [nTPM]":"10.4","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"8.1","Tissue RNA - seminal vesicle [nTPM]":"8.7","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"6.8","Tissue RNA - small intestine [nTPM]":"24.6","Tissue RNA - smooth muscle [nTPM]":"6.6","Tissue RNA - spinal cord [nTPM]":"17.5","Tissue RNA - spleen [nTPM]":"3.0","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"23.3","Tissue RNA - thalamus [nTPM]":"16.9","Tissue RNA - thymus [nTPM]":"47.8","Tissue RNA - thyroid gland [nTPM]":"4.0","Tissue RNA - tongue [nTPM]":"1.9","Tissue RNA - tonsil [nTPM]":"6.5","Tissue RNA - urinary bladder [nTPM]":"8.6","Tissue RNA - vagina [nTPM]":"7.8","Tissue RNA - white matter [nTPM]":"16.2","Cell RNA - A-431 [nTPM]":"3.5","Cell RNA - A549 [nTPM]":"8.6","Cell RNA - AF22 [nTPM]":"24.2","Cell RNA - AN3-CA [nTPM]":"44.0","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"1.4","Cell RNA - BEWO [nTPM]":"18.1","Cell RNA - BJ [nTPM]":"2.4","Cell RNA - BJ hTERT+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"9.6","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"4.8","Cell RNA - fHDF\/TERT166 [nTPM]":"11.3","Cell RNA - GAMG [nTPM]":"39.0","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"38.6","Cell RNA - HBEC3-KT [nTPM]":"7.7","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"21.7","Cell RNA - HEK 293 [nTPM]":"26.8","Cell RNA - HEL [nTPM]":"2.6","Cell RNA - HeLa [nTPM]":"1.6","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"3.4","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"3.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.5","Cell RNA - hTERT-HME1 [nTPM]":"2.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.0","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"13.0","Cell RNA - K-562 [nTPM]":"9.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"3.7","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"1.1","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"31.1","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"16.9","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"38.8","Cell RNA - SH-SY5Y [nTPM]":"40.1","Cell RNA - SiHa [nTPM]":"5.9","Cell RNA - SK-BR-3 [nTPM]":"3.1","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"49.2","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"2.6","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"20.3","Cell RNA - U-2197 [nTPM]":"2.2","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"6.7","Cell RNA - U-87 MG [nTPM]":"1.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"5.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"18.7","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"16.7","Brain RNA - basal ganglia [nTPM]":"16.9","Brain RNA - cerebellum [nTPM]":"15.9","Brain RNA - cerebral cortex [nTPM]":"22.9","Brain RNA - hippocampal formation [nTPM]":"18.1","Brain RNA - hypothalamus [nTPM]":"17.4","Brain RNA - medulla oblongata [nTPM]":"20.1","Brain RNA - midbrain [nTPM]":"18.3","Brain RNA - pons [nTPM]":"20.1","Brain RNA - spinal cord [nTPM]":"17.5","Brain RNA - thalamus [nTPM]":"16.9","Brain RNA - white matter [nTPM]":"16.2","Single Cell Type RNA - Adipocytes [nTPM]":"11.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"17.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"73.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.5","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"269.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"18.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"16.2","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.9","Single Cell Type RNA - Spermatocytes [nTPM]":"10.0","Single Cell Type RNA - Spermatogonia [nTPM]":"17.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"18.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"CILK1","Gene synonym":["ICK","KIAA0936","LCK2","MGC46090","MRK"],"Ensembl":"ENSG00000112144","Gene description":"Ciliogenesis associated kinase 1","Uniprot":["Q9UPZ9"],"Chromosome":"6","Position":"53001279-53061824","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"11.0","Cytotrophoblasts":"20.6","Extravillous trophoblasts":"33.9","Syncytiotrophoblasts":"58.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000791","HPA001113"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA000791":"AB_2732392","HPA001113":"AB_1851385"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"10.2","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"10.7","Tissue RNA - cerebellum [nTPM]":"8.4","Tissue RNA - cerebral cortex [nTPM]":"9.7","Tissue RNA - cervix [nTPM]":"8.9","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"8.7","Tissue RNA - duodenum [nTPM]":"9.8","Tissue RNA - endometrium 1 [nTPM]":"8.0","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"6.9","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"7.8","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"7.5","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"5.2","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"11.6","Tissue RNA - ovary [nTPM]":"9.5","Tissue RNA - pancreas [nTPM]":"5.0","Tissue RNA - parathyroid gland [nTPM]":"7.3","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"8.8","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"17.4","Tissue RNA - salivary gland [nTPM]":"17.9","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"4.0","Tissue RNA - skin 1 [nTPM]":"8.7","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"8.8","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"14.9","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"12.8","Cell RNA - A-431 [nTPM]":"7.8","Cell RNA - A549 [nTPM]":"2.9","Cell RNA - AF22 [nTPM]":"14.6","Cell RNA - AN3-CA [nTPM]":"10.0","Cell RNA - ASC diff [nTPM]":"8.9","Cell RNA - ASC TERT1 [nTPM]":"14.0","Cell RNA - BEWO [nTPM]":"17.0","Cell RNA - BJ [nTPM]":"6.9","Cell RNA - BJ hTERT+ [nTPM]":"12.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.3","Cell RNA - CACO-2 [nTPM]":"4.1","Cell RNA - CAPAN-2 [nTPM]":"2.4","Cell RNA - Daudi [nTPM]":"5.7","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"21.0","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"5.0","Cell RNA - HAP1 [nTPM]":"17.6","Cell RNA - HBEC3-KT [nTPM]":"7.1","Cell RNA - HBF TERT88 [nTPM]":"14.2","Cell RNA - HDLM-2 [nTPM]":"19.9","Cell RNA - HEK 293 [nTPM]":"7.0","Cell RNA - HEL [nTPM]":"4.2","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"22.3","Cell RNA - HHSteC [nTPM]":"4.5","Cell RNA - HL-60 [nTPM]":"5.2","Cell RNA - HMC-1 [nTPM]":"5.4","Cell RNA - HSkMC [nTPM]":"12.5","Cell RNA - hTCEpi [nTPM]":"7.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.6","Cell RNA - hTERT-HME1 [nTPM]":"5.3","Cell RNA - hTERT-RPE1 [nTPM]":"7.7","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"12.1","Cell RNA - K-562 [nTPM]":"8.1","Cell RNA - Karpas-707 [nTPM]":"22.6","Cell RNA - LHCN-M2 [nTPM]":"24.9","Cell RNA - MCF7 [nTPM]":"6.7","Cell RNA - MOLT-4 [nTPM]":"5.6","Cell RNA - NB-4 [nTPM]":"6.4","Cell RNA - NTERA-2 [nTPM]":"5.6","Cell RNA - OE19 [nTPM]":"27.0","Cell RNA - PC-3 [nTPM]":"6.3","Cell RNA - REH [nTPM]":"8.8","Cell RNA - RH-30 [nTPM]":"6.5","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"4.5","Cell RNA - RT4 [nTPM]":"5.6","Cell RNA - SCLC-21H [nTPM]":"23.6","Cell RNA - SH-SY5Y [nTPM]":"10.6","Cell RNA - SiHa [nTPM]":"6.7","Cell RNA - SK-BR-3 [nTPM]":"16.3","Cell RNA - SK-MEL-30 [nTPM]":"9.6","Cell RNA - SuSa [nTPM]":"14.2","Cell RNA - T-47d [nTPM]":"9.5","Cell RNA - THP-1 [nTPM]":"10.9","Cell RNA - TIME [nTPM]":"8.5","Cell RNA - U-138 MG [nTPM]":"17.2","Cell RNA - U-2 OS [nTPM]":"8.0","Cell RNA - U-2197 [nTPM]":"6.5","Cell RNA - U-251 MG [nTPM]":"17.1","Cell RNA - U-266\/70 [nTPM]":"6.3","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"2.2","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"5.0","Cell RNA - WM-115 [nTPM]":"8.5","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"10.2","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"8.4","Brain RNA - cerebral cortex [nTPM]":"9.7","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"7.8","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"11.6","Brain RNA - pons [nTPM]":"8.8","Brain RNA - spinal cord [nTPM]":"8.8","Brain RNA - thalamus [nTPM]":"14.9","Brain RNA - white matter [nTPM]":"12.8","Single Cell Type RNA - Adipocytes [nTPM]":"6.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.6","Single Cell Type RNA - dendritic cells [nTPM]":"5.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.9","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"58.1","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CLCN2","Gene synonym":["ClC-2","CLC2","EJM6"],"Ensembl":"ENSG00000114859","Gene description":"Chloride voltage-gated channel 2","Uniprot":["P51788"],"Chromosome":"3","Position":"184346185-184361650","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"16.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"81.7","Proximal enterocytes":"27.4","Theca cells":"62.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009397","HPA014545","HPA024108"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009397":"AB_2079256","HPA014545":"AB_1846881","HPA024108":"AB_1846883"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.67e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.4","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"16.2","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"3.8","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"7.5","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"2.4","Tissue RNA - kidney [nTPM]":"3.0","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"4.0","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"10.8","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"2.8","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"8.4","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"1.5","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"10.6","Tissue RNA - thalamus [nTPM]":"3.3","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"2.0","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"8.9","Cell RNA - A549 [nTPM]":"3.2","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"6.9","Cell RNA - ASC diff [nTPM]":"2.2","Cell RNA - ASC TERT1 [nTPM]":"1.8","Cell RNA - BEWO [nTPM]":"5.8","Cell RNA - BJ [nTPM]":"2.9","Cell RNA - BJ hTERT+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"16.8","Cell RNA - CAPAN-2 [nTPM]":"3.0","Cell RNA - Daudi [nTPM]":"3.0","Cell RNA - EFO-21 [nTPM]":"8.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1.6","Cell RNA - GAMG [nTPM]":"8.0","Cell RNA - HaCaT [nTPM]":"15.1","Cell RNA - HAP1 [nTPM]":"3.6","Cell RNA - HBEC3-KT [nTPM]":"3.5","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"2.8","Cell RNA - HEK 293 [nTPM]":"4.2","Cell RNA - HEL [nTPM]":"2.7","Cell RNA - HeLa [nTPM]":"7.0","Cell RNA - Hep G2 [nTPM]":"7.7","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"2.6","Cell RNA - HSkMC [nTPM]":"3.6","Cell RNA - hTCEpi [nTPM]":"2.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.6","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"3.3","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"1.6","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"5.9","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"1.6","Cell RNA - NTERA-2 [nTPM]":"3.7","Cell RNA - OE19 [nTPM]":"7.6","Cell RNA - PC-3 [nTPM]":"4.4","Cell RNA - REH [nTPM]":"5.4","Cell RNA - RH-30 [nTPM]":"2.3","Cell RNA - RPMI-8226 [nTPM]":"10.7","Cell RNA - RPTEC TERT1 [nTPM]":"3.8","Cell RNA - RT4 [nTPM]":"6.9","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"2.4","Cell RNA - SiHa [nTPM]":"3.3","Cell RNA - SK-BR-3 [nTPM]":"11.4","Cell RNA - SK-MEL-30 [nTPM]":"5.2","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"9.4","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"1.4","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"4.5","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"7.7","Cell RNA - U-266\/70 [nTPM]":"3.6","Cell RNA - U-266\/84 [nTPM]":"5.5","Cell RNA - U-698 [nTPM]":"2.1","Cell RNA - U-87 MG [nTPM]":"2.7","Cell RNA - U-937 [nTPM]":"5.3","Cell RNA - WM-115 [nTPM]":"7.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"2.4","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"3.3","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"1.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"81.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.2","Single Cell Type RNA - Paneth cells [nTPM]":"16.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"62.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"CLDN14","Gene synonym":["DFNB29"],"Ensembl":"ENSG00000159261","Gene description":"Claudin 14","Uniprot":["O95500"],"Chromosome":"21","Position":"36460621-36576569","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"kidney":"13.8","liver":"39.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"7.2","Distal tubular cells":"19.6","Ductal cells":"11.8","Exocrine glandular cells":"8.2","Hepatocytes":"22.2","Pancreatic endocrine cells":"21.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"liver cancer":"7.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"1.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"HDLM-2":"224.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054707"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA054707":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.53e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"13.8","Tissue RNA - liver [nTPM]":"39.5","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"224.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"3.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"5.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"2.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"7.4","Cell RNA - U-138 MG [nTPM]":"4.2","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"6.7","Cell RNA - U-266\/84 [nTPM]":"15.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"11.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"3.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"22.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"6.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"CLIC5","Gene synonym":["DFNB102"],"Ensembl":"ENSG00000112782","Gene description":"Chloride intracellular channel 5","Uniprot":["Q9NZA1"],"Chromosome":"6","Position":"45880827-46080348","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Hearing","Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Chloride channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"102.7","skeletal muscle":"289.7","tongue":"98.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"509.6","Cardiomyocytes":"285.7","Distal enterocytes":"164.2","Late spermatids":"93.8","Proximal enterocytes":"126.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"11.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"5.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"T-cells":"5.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"13.5","EFO-21":"9.2","HDLM-2":"4.7","REH":"11.9","U-266\/70":"12.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074371"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA074371":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"3.2","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"2.9","Tissue RNA - cervix [nTPM]":"19.0","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"28.6","Tissue RNA - duodenum [nTPM]":"20.9","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"102.7","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"54.7","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"70.8","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"3.8","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"16.5","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"2.6","Tissue RNA - rectum [nTPM]":"25.8","Tissue RNA - retina [nTPM]":"16.9","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"289.7","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"36.6","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"44.5","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"98.3","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"0.9","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"13.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"9.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"4.7","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"11.9","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"12.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"5.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"3.2","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"2.9","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"3.8","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"59.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"509.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"285.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"26.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"164.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"52.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"29.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"7.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"93.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"53.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.9","Single Cell Type RNA - Paneth cells [nTPM]":"51.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"3.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"126.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"5.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.5","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"CLRN1","Gene synonym":["RP61","USH3","USH3A"],"Ensembl":"ENSG00000163646","Gene description":"Clarin 1","Uniprot":["P58418"],"Chromosome":"3","Position":"150926163-150972727","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hearing","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"adrenal gland":"4.9","retina":"12.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Muller glia cells":"165.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"30","RNA cell line specific nTPM":{"NTERA-2":"3.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"12.8","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"165.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CNGA1","Gene synonym":["CNCG","CNCG1","CNG1","RCNC1","RCNCa","RP49"],"Ensembl":"ENSG00000198515","Gene description":"Cyclic nucleotide gated channel subunit alpha 1","Uniprot":["P29973"],"Chromosome":"4","Position":"47935977-48016681","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"retina":"264.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"1139.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"4.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"9.2","RT4":"7.2","U-2 OS":"3.0"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076168"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA076168":"AB_2686781"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"9.3","Tissue RNA - esophagus [nTPM]":"9.0","Tissue RNA - fallopian tube [nTPM]":"4.1","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"23.5","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"2.6","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"264.4","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"3.4","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"3.7","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"0.9","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"2.0","Cell RNA - CAPAN-2 [nTPM]":"9.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"2.7","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"7.2","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"3.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"7.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"97.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"91.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"8.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"38.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"163.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1139.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"35.1"},{"Gene":"CNGA3","Gene synonym":["ACHM2","CCNC1","CCNCa","CNCG3","CNG3"],"Ensembl":"ENSG00000144191","Gene description":"Cyclic nucleotide gated channel subunit alpha 3","Uniprot":["Q16281"],"Chromosome":"2","Position":"98346188-98398601","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.7","intestine":"4.2","pituitary gland":"10.1","retina":"5.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"43.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"7.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"U-87 MG":"6.8"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"basal ganglia":"1.8","hypothalamus":"1.9"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049378","CAB079025"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079025":null,"HPA049378":"AB_2732551"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"5.7","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"6.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"5.7","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CNGB1","Gene synonym":["CNCG2","CNCG3L","CNGB1B","GAR1","GARP","RCNC2","RCNCb","RP45"],"Ensembl":"ENSG00000070729","Gene description":"Cyclic nucleotide gated channel subunit beta 1","Uniprot":["Q14028"],"Chromosome":"16","Position":"57882340-57971128","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Olfaction","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"retina":"600.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"331.5","Rod photoreceptor cells":"1111.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"head and neck cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"1.5","RPMI-8226":"1.8","SCLC-21H":"5.0","SiHa":"2.9","SK-BR-3":"1.4"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"4.5"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039159","HPA060355"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA039159":"AB_10795579","HPA060355":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"15.5","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"13.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"20.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"24.5","Tissue RNA - hypothalamus [nTPM]":"24.8","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"4.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"600.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"36.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"5.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.9","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"15.5","Brain RNA - basal ganglia [nTPM]":"13.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"20.4","Brain RNA - hippocampal formation [nTPM]":"24.5","Brain RNA - hypothalamus [nTPM]":"24.8","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"4.4","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"36.3","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"61.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"331.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"89.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1111.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CNGB3","Gene synonym":["ACHM1","ACHM3","RMCH"],"Ensembl":"ENSG00000170289","Gene description":"Cyclic nucleotide gated channel subunit beta 3","Uniprot":["Q9NQW8"],"Chromosome":"8","Position":"86553977-86743675","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Stargardt disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"4.1","retina":"13.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"158.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"SCLC-21H":"18.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057244"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057244":"AB_2683380"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"4.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"13.1","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"18.9","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"158.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CNNM2","Gene synonym":["ACDP2"],"Ensembl":"ENSG00000148842","Gene description":"Cyclin and CBS domain divalent metal cation transport mediator 2","Uniprot":["Q9H8M5"],"Chromosome":"10","Position":"102918294-103090222","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"37.9","parathyroid gland":"31.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"60.1","Excitatory neurons":"112.6","Inhibitory neurons":"146.9","Oligodendrocyte precursor cells":"92.5","Oligodendrocytes":"92.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"NK-cell":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"NK-cells":"1.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059954","HPA071631"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059954":"AB_2684177","HPA071631":"AB_2686427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.39e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"11.5","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"2.3","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"9.3","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"7.9","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"37.9","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"9.1","Tissue RNA - liver [nTPM]":"4.8","Tissue RNA - lung [nTPM]":"3.8","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"3.6","Tissue RNA - parathyroid gland [nTPM]":"31.6","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"8.7","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"3.0","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"3.2","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"5.0","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"8.5","Cell RNA - ASC diff [nTPM]":"7.8","Cell RNA - ASC TERT1 [nTPM]":"3.2","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.9","Cell RNA - CACO-2 [nTPM]":"5.8","Cell RNA - CAPAN-2 [nTPM]":"4.3","Cell RNA - Daudi [nTPM]":"1.9","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.4","Cell RNA - GAMG [nTPM]":"6.0","Cell RNA - HaCaT [nTPM]":"6.3","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"12.1","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"4.2","Cell RNA - Hep G2 [nTPM]":"11.8","Cell RNA - HHSteC [nTPM]":"4.6","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"3.6","Cell RNA - HSkMC [nTPM]":"4.2","Cell RNA - hTCEpi [nTPM]":"6.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.2","Cell RNA - hTERT-HME1 [nTPM]":"10.7","Cell RNA - hTERT-RPE1 [nTPM]":"7.9","Cell RNA - HUVEC TERT2 [nTPM]":"1.9","Cell RNA - JURKAT [nTPM]":"5.5","Cell RNA - K-562 [nTPM]":"4.8","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"8.6","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"2.2","Cell RNA - NTERA-2 [nTPM]":"5.1","Cell RNA - OE19 [nTPM]":"4.9","Cell RNA - PC-3 [nTPM]":"5.0","Cell RNA - REH [nTPM]":"5.5","Cell RNA - RH-30 [nTPM]":"4.0","Cell RNA - RPMI-8226 [nTPM]":"2.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.4","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"5.8","Cell RNA - SiHa [nTPM]":"5.9","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"6.3","Cell RNA - SuSa [nTPM]":"9.1","Cell RNA - T-47d [nTPM]":"10.4","Cell RNA - THP-1 [nTPM]":"3.7","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"4.2","Cell RNA - U-2 OS [nTPM]":"6.2","Cell RNA - U-2197 [nTPM]":"3.0","Cell RNA - U-251 MG [nTPM]":"4.2","Cell RNA - U-266\/70 [nTPM]":"11.7","Cell RNA - U-266\/84 [nTPM]":"14.1","Cell RNA - U-698 [nTPM]":"3.6","Cell RNA - U-87 MG [nTPM]":"7.4","Cell RNA - U-937 [nTPM]":"6.6","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"7.9","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"3.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"60.1","Single Cell Type RNA - B-cells [nTPM]":"7.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"16.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.8","Single Cell Type RNA - dendritic cells [nTPM]":"8.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"46.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.2","Single Cell Type RNA - Early spermatids [nTPM]":"10.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"112.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.4","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.4","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"13.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.8","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"146.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"15.1","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"4.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"92.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"92.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"9.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"6.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.7","Single Cell Type RNA - Spermatocytes [nTPM]":"15.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.8","Single Cell Type RNA - T-cells [nTPM]":"5.1","Single Cell Type RNA - Theca cells [nTPM]":"3.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.6","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"CNNM4","Gene synonym":["ACDP4","KIAA1592"],"Ensembl":"ENSG00000158158","Gene description":"Cyclin and CBS domain divalent metal cation transport mediator 4","Uniprot":["Q6P4Q7"],"Chromosome":"2","Position":"96760902-96811874","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Biomineralization","Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"38.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"112.6","Distal enterocytes":"103.4","Rod photoreceptor cells":"51.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"45.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017732"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA017732":"AB_1847395"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.14e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.75e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.8","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"6.1","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"11.2","Tissue RNA - cerebral cortex [nTPM]":"5.4","Tissue RNA - cervix [nTPM]":"5.8","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"32.4","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"10.4","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"12.5","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"4.4","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"9.1","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"5.7","Tissue RNA - rectum [nTPM]":"34.3","Tissue RNA - retina [nTPM]":"38.8","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"5.1","Tissue RNA - skeletal muscle [nTPM]":"24.8","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"11.3","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"5.3","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"7.9","Tissue RNA - thalamus [nTPM]":"4.5","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"13.1","Tissue RNA - tonsil [nTPM]":"4.9","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"5.7","Cell RNA - A-431 [nTPM]":"11.1","Cell RNA - A549 [nTPM]":"7.2","Cell RNA - AF22 [nTPM]":"5.7","Cell RNA - AN3-CA [nTPM]":"10.5","Cell RNA - ASC diff [nTPM]":"5.8","Cell RNA - ASC TERT1 [nTPM]":"3.9","Cell RNA - BEWO [nTPM]":"15.6","Cell RNA - BJ [nTPM]":"4.8","Cell RNA - BJ hTERT+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.3","Cell RNA - CACO-2 [nTPM]":"13.2","Cell RNA - CAPAN-2 [nTPM]":"11.8","Cell RNA - Daudi [nTPM]":"8.1","Cell RNA - EFO-21 [nTPM]":"13.5","Cell RNA - fHDF\/TERT166 [nTPM]":"5.0","Cell RNA - GAMG [nTPM]":"9.5","Cell RNA - HaCaT [nTPM]":"14.1","Cell RNA - HAP1 [nTPM]":"14.9","Cell RNA - HBEC3-KT [nTPM]":"8.1","Cell RNA - HBF TERT88 [nTPM]":"6.3","Cell RNA - HDLM-2 [nTPM]":"16.3","Cell RNA - HEK 293 [nTPM]":"11.7","Cell RNA - HEL [nTPM]":"6.4","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"7.2","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"3.1","Cell RNA - HMC-1 [nTPM]":"6.2","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"10.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.0","Cell RNA - hTERT-HME1 [nTPM]":"6.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.6","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"3.3","Cell RNA - Karpas-707 [nTPM]":"22.3","Cell RNA - LHCN-M2 [nTPM]":"3.6","Cell RNA - MCF7 [nTPM]":"15.7","Cell RNA - MOLT-4 [nTPM]":"6.6","Cell RNA - NB-4 [nTPM]":"4.5","Cell RNA - NTERA-2 [nTPM]":"7.5","Cell RNA - OE19 [nTPM]":"20.5","Cell RNA - PC-3 [nTPM]":"9.8","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"9.3","Cell RNA - RPTEC TERT1 [nTPM]":"6.9","Cell RNA - RT4 [nTPM]":"8.6","Cell RNA - SCLC-21H [nTPM]":"26.7","Cell RNA - SH-SY5Y [nTPM]":"8.0","Cell RNA - SiHa [nTPM]":"9.1","Cell RNA - SK-BR-3 [nTPM]":"45.7","Cell RNA - SK-MEL-30 [nTPM]":"6.8","Cell RNA - SuSa [nTPM]":"15.9","Cell RNA - T-47d [nTPM]":"22.3","Cell RNA - THP-1 [nTPM]":"5.3","Cell RNA - TIME [nTPM]":"3.4","Cell RNA - U-138 MG [nTPM]":"4.0","Cell RNA - U-2 OS [nTPM]":"8.9","Cell RNA - U-2197 [nTPM]":"8.8","Cell RNA - U-251 MG [nTPM]":"5.4","Cell RNA - U-266\/70 [nTPM]":"7.7","Cell RNA - U-266\/84 [nTPM]":"6.6","Cell RNA - U-698 [nTPM]":"4.0","Cell RNA - U-87 MG [nTPM]":"5.9","Cell RNA - U-937 [nTPM]":"6.1","Cell RNA - WM-115 [nTPM]":"7.2","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"11.2","Brain RNA - cerebral cortex [nTPM]":"5.4","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"4.5","Brain RNA - white matter [nTPM]":"5.7","Single Cell Type RNA - Adipocytes [nTPM]":"4.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"6.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"43.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"11.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"112.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.4","Single Cell Type RNA - dendritic cells [nTPM]":"6.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"103.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"5.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.3","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"5.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"21.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"51.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"4.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"5.4","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"CNPY3","Gene synonym":["CAG4A","TNRC5"],"Ensembl":"ENSG00000137161","Gene description":"Canopy FGF signaling regulator 3","Uniprot":["Q9BT09"],"Chromosome":"6","Position":"42929192-42939294","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Chaperone"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"248.5","Kupffer cells":"233.3","monocytes":"207.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016560"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4100000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016560":"AB_1858173"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.85e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Tissue RNA - adipose tissue [nTPM]":"35.3","Tissue RNA - adrenal gland [nTPM]":"31.4","Tissue RNA - amygdala [nTPM]":"58.2","Tissue RNA - appendix [nTPM]":"64.3","Tissue RNA - basal ganglia [nTPM]":"59.1","Tissue RNA - bone marrow [nTPM]":"144.6","Tissue RNA - breast [nTPM]":"32.7","Tissue RNA - cerebellum [nTPM]":"59.0","Tissue RNA - cerebral cortex [nTPM]":"72.8","Tissue RNA - cervix [nTPM]":"40.0","Tissue RNA - choroid plexus [nTPM]":"70.0","Tissue RNA - colon [nTPM]":"30.9","Tissue RNA - duodenum [nTPM]":"30.9","Tissue RNA - endometrium 1 [nTPM]":"37.5","Tissue RNA - epididymis [nTPM]":"32.3","Tissue RNA - esophagus [nTPM]":"23.4","Tissue RNA - fallopian tube [nTPM]":"49.8","Tissue RNA - gallbladder [nTPM]":"37.8","Tissue RNA - heart muscle [nTPM]":"28.8","Tissue RNA - hippocampal formation [nTPM]":"59.7","Tissue RNA - hypothalamus [nTPM]":"64.2","Tissue RNA - kidney [nTPM]":"31.8","Tissue RNA - liver [nTPM]":"64.7","Tissue RNA - lung [nTPM]":"45.4","Tissue RNA - lymph node [nTPM]":"78.6","Tissue RNA - medulla oblongata [nTPM]":"70.0","Tissue RNA - midbrain [nTPM]":"63.1","Tissue RNA - ovary [nTPM]":"48.5","Tissue RNA - pancreas [nTPM]":"90.0","Tissue RNA - parathyroid gland [nTPM]":"29.0","Tissue RNA - pituitary gland [nTPM]":"41.7","Tissue RNA - placenta [nTPM]":"47.6","Tissue RNA - pons [nTPM]":"67.0","Tissue RNA - prostate [nTPM]":"45.1","Tissue RNA - rectum [nTPM]":"29.7","Tissue RNA - retina [nTPM]":"23.9","Tissue RNA - salivary gland [nTPM]":"32.5","Tissue RNA - seminal vesicle [nTPM]":"33.8","Tissue RNA - skeletal muscle [nTPM]":"10.9","Tissue RNA - skin 1 [nTPM]":"22.2","Tissue RNA - small intestine [nTPM]":"50.1","Tissue RNA - smooth muscle [nTPM]":"42.0","Tissue RNA - spinal cord [nTPM]":"62.8","Tissue RNA - spleen [nTPM]":"105.2","Tissue RNA - stomach 1 [nTPM]":"36.7","Tissue RNA - testis [nTPM]":"46.7","Tissue RNA - thalamus [nTPM]":"65.8","Tissue RNA - thymus [nTPM]":"115.8","Tissue RNA - thyroid gland [nTPM]":"34.1","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"69.2","Tissue RNA - urinary bladder [nTPM]":"43.3","Tissue RNA - vagina [nTPM]":"30.0","Tissue RNA - white matter [nTPM]":"75.8","Cell RNA - A-431 [nTPM]":"78.2","Cell RNA - A549 [nTPM]":"75.6","Cell RNA - AF22 [nTPM]":"72.8","Cell RNA - AN3-CA [nTPM]":"157.0","Cell RNA - ASC diff [nTPM]":"118.4","Cell RNA - ASC TERT1 [nTPM]":"44.8","Cell RNA - BEWO [nTPM]":"73.5","Cell RNA - BJ [nTPM]":"60.3","Cell RNA - BJ hTERT+ [nTPM]":"78.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"79.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.0","Cell RNA - CACO-2 [nTPM]":"85.2","Cell RNA - CAPAN-2 [nTPM]":"57.0","Cell RNA - Daudi [nTPM]":"82.1","Cell RNA - EFO-21 [nTPM]":"91.0","Cell RNA - fHDF\/TERT166 [nTPM]":"102.9","Cell RNA - GAMG [nTPM]":"170.8","Cell RNA - HaCaT [nTPM]":"63.7","Cell RNA - HAP1 [nTPM]":"54.7","Cell RNA - HBEC3-KT [nTPM]":"68.7","Cell RNA - HBF TERT88 [nTPM]":"48.2","Cell RNA - HDLM-2 [nTPM]":"82.7","Cell RNA - HEK 293 [nTPM]":"61.6","Cell RNA - HEL [nTPM]":"88.6","Cell RNA - HeLa [nTPM]":"65.2","Cell RNA - Hep G2 [nTPM]":"134.0","Cell RNA - HHSteC [nTPM]":"70.0","Cell RNA - HL-60 [nTPM]":"155.7","Cell RNA - HMC-1 [nTPM]":"173.3","Cell RNA - HSkMC [nTPM]":"54.3","Cell RNA - hTCEpi [nTPM]":"41.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"61.2","Cell RNA - hTERT-HME1 [nTPM]":"67.4","Cell RNA - hTERT-RPE1 [nTPM]":"113.9","Cell RNA - HUVEC TERT2 [nTPM]":"72.4","Cell RNA - JURKAT [nTPM]":"77.6","Cell RNA - K-562 [nTPM]":"73.3","Cell RNA - Karpas-707 [nTPM]":"157.3","Cell RNA - LHCN-M2 [nTPM]":"51.9","Cell RNA - MCF7 [nTPM]":"147.9","Cell RNA - MOLT-4 [nTPM]":"141.4","Cell RNA - NB-4 [nTPM]":"188.8","Cell RNA - NTERA-2 [nTPM]":"59.1","Cell RNA - OE19 [nTPM]":"367.3","Cell RNA - PC-3 [nTPM]":"42.1","Cell RNA - REH [nTPM]":"97.2","Cell RNA - RH-30 [nTPM]":"50.6","Cell RNA - RPMI-8226 [nTPM]":"123.2","Cell RNA - RPTEC TERT1 [nTPM]":"79.6","Cell RNA - RT4 [nTPM]":"58.6","Cell RNA - SCLC-21H [nTPM]":"78.5","Cell RNA - SH-SY5Y [nTPM]":"68.9","Cell RNA - SiHa [nTPM]":"37.7","Cell RNA - SK-BR-3 [nTPM]":"38.6","Cell RNA - SK-MEL-30 [nTPM]":"134.4","Cell RNA - SuSa [nTPM]":"93.4","Cell RNA - T-47d [nTPM]":"49.8","Cell RNA - THP-1 [nTPM]":"334.6","Cell RNA - TIME [nTPM]":"54.6","Cell RNA - U-138 MG [nTPM]":"82.7","Cell RNA - U-2 OS [nTPM]":"82.9","Cell RNA - U-2197 [nTPM]":"30.9","Cell RNA - U-251 MG [nTPM]":"66.0","Cell RNA - U-266\/70 [nTPM]":"107.0","Cell RNA - U-266\/84 [nTPM]":"78.9","Cell RNA - U-698 [nTPM]":"115.0","Cell RNA - U-87 MG [nTPM]":"34.2","Cell RNA - U-937 [nTPM]":"178.6","Cell RNA - WM-115 [nTPM]":"70.9","Blood RNA - basophil [nTPM]":"212.7","Blood RNA - classical monocyte [nTPM]":"483.3","Blood RNA - eosinophil [nTPM]":"249.0","Blood RNA - gdT-cell [nTPM]":"115.2","Blood RNA - intermediate monocyte [nTPM]":"336.3","Blood RNA - MAIT T-cell [nTPM]":"110.9","Blood RNA - memory B-cell [nTPM]":"267.3","Blood RNA - memory CD4 T-cell [nTPM]":"101.1","Blood RNA - memory CD8 T-cell [nTPM]":"126.1","Blood RNA - myeloid DC [nTPM]":"407.0","Blood RNA - naive B-cell [nTPM]":"258.7","Blood RNA - naive CD4 T-cell [nTPM]":"112.6","Blood RNA - naive CD8 T-cell [nTPM]":"115.1","Blood RNA - neutrophil [nTPM]":"852.8","Blood RNA - NK-cell [nTPM]":"132.3","Blood RNA - non-classical monocyte [nTPM]":"327.2","Blood RNA - plasmacytoid DC [nTPM]":"696.4","Blood RNA - T-reg [nTPM]":"102.2","Blood RNA - total PBMC [nTPM]":"404.5","Brain RNA - amygdala [nTPM]":"58.2","Brain RNA - basal ganglia [nTPM]":"59.1","Brain RNA - cerebellum [nTPM]":"59.0","Brain RNA - cerebral cortex [nTPM]":"72.8","Brain RNA - hippocampal formation [nTPM]":"59.7","Brain RNA - hypothalamus [nTPM]":"64.2","Brain RNA - medulla oblongata [nTPM]":"70.0","Brain RNA - midbrain [nTPM]":"63.1","Brain RNA - pons [nTPM]":"67.0","Brain RNA - spinal cord [nTPM]":"62.8","Brain RNA - thalamus [nTPM]":"65.8","Brain RNA - white matter [nTPM]":"75.8","Single Cell Type RNA - Adipocytes [nTPM]":"32.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"132.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"41.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"41.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"26.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"51.1","Single Cell Type RNA - dendritic cells [nTPM]":"176.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"47.4","Single Cell Type RNA - Early spermatids [nTPM]":"61.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.2","Single Cell Type RNA - Endothelial cells [nTPM]":"36.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"55.3","Single Cell Type RNA - Erythroid cells [nTPM]":"47.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"180.8","Single Cell Type RNA - Fibroblasts [nTPM]":"33.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.8","Single Cell Type RNA - granulocytes [nTPM]":"46.3","Single Cell Type RNA - Granulosa cells [nTPM]":"81.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.1","Single Cell Type RNA - Hepatocytes [nTPM]":"58.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"248.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.1","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"233.3","Single Cell Type RNA - Langerhans cells [nTPM]":"61.7","Single Cell Type RNA - Late spermatids [nTPM]":"81.7","Single Cell Type RNA - Leydig cells [nTPM]":"33.5","Single Cell Type RNA - Macrophages [nTPM]":"184.3","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"207.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.8","Single Cell Type RNA - NK-cells [nTPM]":"62.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.9","Single Cell Type RNA - Paneth cells [nTPM]":"34.9","Single Cell Type RNA - Peritubular cells [nTPM]":"30.1","Single Cell Type RNA - Plasma cells [nTPM]":"70.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.0","Single Cell Type RNA - Spermatocytes [nTPM]":"72.3","Single Cell Type RNA - Spermatogonia [nTPM]":"39.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.1","Single Cell Type RNA - T-cells [nTPM]":"64.1","Single Cell Type RNA - Theca cells [nTPM]":"39.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.5","Single Cell Type RNA - Urothelial cells [nTPM]":"37.9"},{"Gene":"CNTN2","Gene synonym":["AXT","TAG-1","TAX","TAX1"],"Ensembl":"ENSG00000184144","Gene description":"Contactin 2","Uniprot":["Q02246"],"Chromosome":"1","Position":"205042937-205078289","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"248.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Oligodendrocytes":"335.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"6.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"NTERA-2":"3.9","SCLC-21H":"9.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001397","HPA012497"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001397":"AB_1847146","HPA012497":"AB_1847147"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"82.6","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"145.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"125.7","Tissue RNA - cerebral cortex [nTPM]":"112.4","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"32.4","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"85.2","Tissue RNA - hypothalamus [nTPM]":"96.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"161.6","Tissue RNA - midbrain [nTPM]":"128.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"139.8","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"110.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"125.7","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"248.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"9.5","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"82.6","Brain RNA - basal ganglia [nTPM]":"145.4","Brain RNA - cerebellum [nTPM]":"125.7","Brain RNA - cerebral cortex [nTPM]":"112.4","Brain RNA - hippocampal formation [nTPM]":"85.2","Brain RNA - hypothalamus [nTPM]":"96.6","Brain RNA - medulla oblongata [nTPM]":"161.6","Brain RNA - midbrain [nTPM]":"128.1","Brain RNA - pons [nTPM]":"139.8","Brain RNA - spinal cord [nTPM]":"110.1","Brain RNA - thalamus [nTPM]":"125.7","Brain RNA - white matter [nTPM]":"248.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"13.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"29.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"335.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CNTNAP1","Gene synonym":["Caspr","CNTNAP","NRXN4","p190"],"Ensembl":"ENSG00000108797","Gene description":"Contactin associated protein 1","Uniprot":["P78357"],"Chromosome":"17","Position":"42682531-42699993","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"46.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"11.4","Bipolar cells":"15.6","Endometrial stromal cells":"15.5","Excitatory neurons":"45.6","Inhibitory neurons":"37.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"10.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"43.5","TIME":"68.5","U-138 MG":"76.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011772"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA011772":"AB_1079541"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.16e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-3"},"Tissue RNA - adipose tissue [nTPM]":"7.1","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"27.5","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"30.8","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"5.0","Tissue RNA - cerebellum [nTPM]":"13.5","Tissue RNA - cerebral cortex [nTPM]":"46.7","Tissue RNA - cervix [nTPM]":"12.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"23.8","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"21.8","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"8.2","Tissue RNA - hippocampal formation [nTPM]":"29.5","Tissue RNA - hypothalamus [nTPM]":"15.7","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"6.9","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"21.6","Tissue RNA - midbrain [nTPM]":"15.4","Tissue RNA - ovary [nTPM]":"15.7","Tissue RNA - pancreas [nTPM]":"11.5","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"19.3","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"19.1","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"11.3","Tissue RNA - salivary gland [nTPM]":"2.9","Tissue RNA - seminal vesicle [nTPM]":"6.5","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"6.0","Tissue RNA - smooth muscle [nTPM]":"25.9","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"4.9","Tissue RNA - stomach 1 [nTPM]":"9.8","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"18.8","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"8.0","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"29.4","Cell RNA - A-431 [nTPM]":"4.1","Cell RNA - A549 [nTPM]":"5.4","Cell RNA - AF22 [nTPM]":"13.2","Cell RNA - AN3-CA [nTPM]":"4.2","Cell RNA - ASC diff [nTPM]":"20.0","Cell RNA - ASC TERT1 [nTPM]":"40.4","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"25.6","Cell RNA - BJ hTERT+ [nTPM]":"43.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.5","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.3","Cell RNA - fHDF\/TERT166 [nTPM]":"27.7","Cell RNA - GAMG [nTPM]":"18.6","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"6.4","Cell RNA - HBEC3-KT [nTPM]":"2.0","Cell RNA - HBF TERT88 [nTPM]":"14.2","Cell RNA - HDLM-2 [nTPM]":"9.0","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"24.0","Cell RNA - Hep G2 [nTPM]":"6.4","Cell RNA - HHSteC [nTPM]":"9.8","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"39.7","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.5","Cell RNA - hTERT-HME1 [nTPM]":"3.5","Cell RNA - hTERT-RPE1 [nTPM]":"29.1","Cell RNA - HUVEC TERT2 [nTPM]":"23.3","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"1.2","Cell RNA - Karpas-707 [nTPM]":"7.6","Cell RNA - LHCN-M2 [nTPM]":"7.1","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"3.8","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"5.5","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"2.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"7.7","Cell RNA - SiHa [nTPM]":"7.6","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"4.7","Cell RNA - SuSa [nTPM]":"12.0","Cell RNA - T-47d [nTPM]":"4.1","Cell RNA - THP-1 [nTPM]":"2.3","Cell RNA - TIME [nTPM]":"68.5","Cell RNA - U-138 MG [nTPM]":"76.2","Cell RNA - U-2 OS [nTPM]":"12.5","Cell RNA - U-2197 [nTPM]":"18.0","Cell RNA - U-251 MG [nTPM]":"7.0","Cell RNA - U-266\/70 [nTPM]":"8.5","Cell RNA - U-266\/84 [nTPM]":"5.7","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"21.4","Cell RNA - U-937 [nTPM]":"1.7","Cell RNA - WM-115 [nTPM]":"11.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"27.5","Brain RNA - basal ganglia [nTPM]":"30.8","Brain RNA - cerebellum [nTPM]":"13.5","Brain RNA - cerebral cortex [nTPM]":"46.7","Brain RNA - hippocampal formation [nTPM]":"29.5","Brain RNA - hypothalamus [nTPM]":"15.7","Brain RNA - medulla oblongata [nTPM]":"21.6","Brain RNA - midbrain [nTPM]":"15.4","Brain RNA - pons [nTPM]":"19.1","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"18.8","Brain RNA - white matter [nTPM]":"29.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"COA7","Gene synonym":["C1orf163","FLJ12439","RESA1","SELRC1"],"Ensembl":"ENSG00000162377","Gene description":"Cytochrome c oxidase assembly factor 7 (putative)","Uniprot":["Q96BR5"],"Chromosome":"1","Position":"52684449-52698347","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028154","HPA029926"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA028154":"AB_10600656","HPA029926":"AB_10602173"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.55e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.01e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.35e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"4.8","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"3.9","Tissue RNA - breast [nTPM]":"7.3","Tissue RNA - cerebellum [nTPM]":"5.2","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"4.6","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"7.9","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"5.5","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"4.6","Tissue RNA - gallbladder [nTPM]":"3.5","Tissue RNA - heart muscle [nTPM]":"5.5","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"12.1","Tissue RNA - lung [nTPM]":"3.9","Tissue RNA - lymph node [nTPM]":"4.0","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"3.7","Tissue RNA - pancreas [nTPM]":"10.7","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"5.2","Tissue RNA - pons [nTPM]":"4.8","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"7.5","Tissue RNA - retina [nTPM]":"4.3","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"3.6","Tissue RNA - skeletal muscle [nTPM]":"16.0","Tissue RNA - skin 1 [nTPM]":"6.5","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"5.9","Tissue RNA - spinal cord [nTPM]":"3.9","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"5.1","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"5.1","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"7.1","Tissue RNA - tongue [nTPM]":"20.4","Tissue RNA - tonsil [nTPM]":"4.5","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"5.7","Cell RNA - A-431 [nTPM]":"26.0","Cell RNA - A549 [nTPM]":"14.5","Cell RNA - AF22 [nTPM]":"13.0","Cell RNA - AN3-CA [nTPM]":"21.1","Cell RNA - ASC diff [nTPM]":"20.7","Cell RNA - ASC TERT1 [nTPM]":"17.9","Cell RNA - BEWO [nTPM]":"28.6","Cell RNA - BJ [nTPM]":"19.1","Cell RNA - BJ hTERT+ [nTPM]":"15.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.5","Cell RNA - CACO-2 [nTPM]":"18.2","Cell RNA - CAPAN-2 [nTPM]":"9.0","Cell RNA - Daudi [nTPM]":"59.4","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"11.4","Cell RNA - GAMG [nTPM]":"29.6","Cell RNA - HaCaT [nTPM]":"19.5","Cell RNA - HAP1 [nTPM]":"31.9","Cell RNA - HBEC3-KT [nTPM]":"27.1","Cell RNA - HBF TERT88 [nTPM]":"30.4","Cell RNA - HDLM-2 [nTPM]":"18.4","Cell RNA - HEK 293 [nTPM]":"31.9","Cell RNA - HEL [nTPM]":"49.9","Cell RNA - HeLa [nTPM]":"22.5","Cell RNA - Hep G2 [nTPM]":"20.9","Cell RNA - HHSteC [nTPM]":"25.5","Cell RNA - HL-60 [nTPM]":"49.7","Cell RNA - HMC-1 [nTPM]":"16.4","Cell RNA - HSkMC [nTPM]":"19.8","Cell RNA - hTCEpi [nTPM]":"23.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.6","Cell RNA - hTERT-HME1 [nTPM]":"33.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.3","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"16.6","Cell RNA - K-562 [nTPM]":"46.5","Cell RNA - Karpas-707 [nTPM]":"10.0","Cell RNA - LHCN-M2 [nTPM]":"17.9","Cell RNA - MCF7 [nTPM]":"17.3","Cell RNA - MOLT-4 [nTPM]":"17.0","Cell RNA - NB-4 [nTPM]":"25.3","Cell RNA - NTERA-2 [nTPM]":"57.7","Cell RNA - OE19 [nTPM]":"27.7","Cell RNA - PC-3 [nTPM]":"40.8","Cell RNA - REH [nTPM]":"32.9","Cell RNA - RH-30 [nTPM]":"44.6","Cell RNA - RPMI-8226 [nTPM]":"43.2","Cell RNA - RPTEC TERT1 [nTPM]":"20.7","Cell RNA - RT4 [nTPM]":"25.9","Cell RNA - SCLC-21H [nTPM]":"29.2","Cell RNA - SH-SY5Y [nTPM]":"15.4","Cell RNA - SiHa [nTPM]":"27.9","Cell RNA - SK-BR-3 [nTPM]":"35.0","Cell RNA - SK-MEL-30 [nTPM]":"36.3","Cell RNA - SuSa [nTPM]":"18.3","Cell RNA - T-47d [nTPM]":"20.5","Cell RNA - THP-1 [nTPM]":"33.4","Cell RNA - TIME [nTPM]":"18.2","Cell RNA - U-138 MG [nTPM]":"18.3","Cell RNA - U-2 OS [nTPM]":"24.0","Cell RNA - U-2197 [nTPM]":"25.5","Cell RNA - U-251 MG [nTPM]":"26.7","Cell RNA - U-266\/70 [nTPM]":"21.2","Cell RNA - U-266\/84 [nTPM]":"57.0","Cell RNA - U-698 [nTPM]":"27.2","Cell RNA - U-87 MG [nTPM]":"8.5","Cell RNA - U-937 [nTPM]":"35.4","Cell RNA - WM-115 [nTPM]":"15.2","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"4.3","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"5.2","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"4.8","Brain RNA - spinal cord [nTPM]":"3.9","Brain RNA - thalamus [nTPM]":"5.1","Brain RNA - white matter [nTPM]":"5.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"4.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"7.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"11.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.0","Single Cell Type RNA - Fibroblasts [nTPM]":"7.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"13.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.7","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"4.7","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"7.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"8.7","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.0","Single Cell Type RNA - Paneth cells [nTPM]":"7.0","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"9.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.6","Single Cell Type RNA - Spermatogonia [nTPM]":"13.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"4.2","Single Cell Type RNA - Theca cells [nTPM]":"10.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.5","Single Cell Type RNA - Urothelial cells [nTPM]":"17.8"},{"Gene":"COASY","Gene synonym":["DPCK","NBP","PPAT"],"Ensembl":"ENSG00000068120","Gene description":"Coenzyme A synthase","Uniprot":["Q13057"],"Chromosome":"17","Position":"42561467-42566277","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Coenzyme A biosynthesis"],"Molecular function":["Kinase","Multifunctional enzyme","Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022875","HPA022912","HPA023273"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA022875":"AB_1847066","HPA022912":"AB_1847067","HPA023273":"AB_1847068"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.15e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.54e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"27.4","Tissue RNA - adrenal gland [nTPM]":"60.0","Tissue RNA - amygdala [nTPM]":"24.0","Tissue RNA - appendix [nTPM]":"23.1","Tissue RNA - basal ganglia [nTPM]":"24.0","Tissue RNA - bone marrow [nTPM]":"29.5","Tissue RNA - breast [nTPM]":"32.8","Tissue RNA - cerebellum [nTPM]":"24.7","Tissue RNA - cerebral cortex [nTPM]":"28.1","Tissue RNA - cervix [nTPM]":"27.6","Tissue RNA - choroid plexus [nTPM]":"26.7","Tissue RNA - colon [nTPM]":"35.6","Tissue RNA - duodenum [nTPM]":"43.3","Tissue RNA - endometrium 1 [nTPM]":"25.2","Tissue RNA - epididymis [nTPM]":"17.2","Tissue RNA - esophagus [nTPM]":"54.4","Tissue RNA - fallopian tube [nTPM]":"29.8","Tissue RNA - gallbladder [nTPM]":"16.9","Tissue RNA - heart muscle [nTPM]":"29.4","Tissue RNA - hippocampal formation [nTPM]":"25.4","Tissue RNA - hypothalamus [nTPM]":"23.9","Tissue RNA - kidney [nTPM]":"45.6","Tissue RNA - liver [nTPM]":"70.9","Tissue RNA - lung [nTPM]":"30.3","Tissue RNA - lymph node [nTPM]":"25.0","Tissue RNA - medulla oblongata [nTPM]":"27.8","Tissue RNA - midbrain [nTPM]":"24.7","Tissue RNA - ovary [nTPM]":"26.0","Tissue RNA - pancreas [nTPM]":"59.0","Tissue RNA - parathyroid gland [nTPM]":"39.0","Tissue RNA - pituitary gland [nTPM]":"30.3","Tissue RNA - placenta [nTPM]":"25.5","Tissue RNA - pons [nTPM]":"28.1","Tissue RNA - prostate [nTPM]":"32.4","Tissue RNA - rectum [nTPM]":"24.3","Tissue RNA - retina [nTPM]":"13.3","Tissue RNA - salivary gland [nTPM]":"58.5","Tissue RNA - seminal vesicle [nTPM]":"28.7","Tissue RNA - skeletal muscle [nTPM]":"38.6","Tissue RNA - skin 1 [nTPM]":"46.6","Tissue RNA - small intestine [nTPM]":"36.9","Tissue RNA - smooth muscle [nTPM]":"17.2","Tissue RNA - spinal cord [nTPM]":"23.8","Tissue RNA - spleen [nTPM]":"35.9","Tissue RNA - stomach 1 [nTPM]":"47.2","Tissue RNA - testis [nTPM]":"32.4","Tissue RNA - thalamus [nTPM]":"25.7","Tissue RNA - thymus [nTPM]":"27.6","Tissue RNA - thyroid gland [nTPM]":"39.0","Tissue RNA - tongue [nTPM]":"25.3","Tissue RNA - tonsil [nTPM]":"25.2","Tissue RNA - urinary bladder [nTPM]":"26.8","Tissue RNA - vagina [nTPM]":"31.1","Tissue RNA - white matter [nTPM]":"24.6","Cell RNA - A-431 [nTPM]":"94.2","Cell RNA - A549 [nTPM]":"149.1","Cell RNA - AF22 [nTPM]":"27.2","Cell RNA - AN3-CA [nTPM]":"55.2","Cell RNA - ASC diff [nTPM]":"55.5","Cell RNA - ASC TERT1 [nTPM]":"34.8","Cell RNA - BEWO [nTPM]":"89.2","Cell RNA - BJ [nTPM]":"38.3","Cell RNA - BJ hTERT+ [nTPM]":"52.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"46.5","Cell RNA - CACO-2 [nTPM]":"85.7","Cell RNA - CAPAN-2 [nTPM]":"89.2","Cell RNA - Daudi [nTPM]":"52.7","Cell RNA - EFO-21 [nTPM]":"65.6","Cell RNA - fHDF\/TERT166 [nTPM]":"50.4","Cell RNA - GAMG [nTPM]":"69.5","Cell RNA - HaCaT [nTPM]":"146.9","Cell RNA - HAP1 [nTPM]":"66.1","Cell RNA - HBEC3-KT [nTPM]":"81.4","Cell RNA - HBF TERT88 [nTPM]":"43.7","Cell RNA - HDLM-2 [nTPM]":"47.6","Cell RNA - HEK 293 [nTPM]":"122.2","Cell RNA - HEL [nTPM]":"52.5","Cell RNA - HeLa [nTPM]":"91.2","Cell RNA - Hep G2 [nTPM]":"140.9","Cell RNA - HHSteC [nTPM]":"70.2","Cell RNA - HL-60 [nTPM]":"56.4","Cell RNA - HMC-1 [nTPM]":"73.1","Cell RNA - HSkMC [nTPM]":"51.5","Cell RNA - hTCEpi [nTPM]":"97.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"62.4","Cell RNA - hTERT-HME1 [nTPM]":"66.6","Cell RNA - hTERT-RPE1 [nTPM]":"52.4","Cell RNA - HUVEC TERT2 [nTPM]":"63.2","Cell RNA - JURKAT [nTPM]":"70.5","Cell RNA - K-562 [nTPM]":"98.7","Cell RNA - Karpas-707 [nTPM]":"70.8","Cell RNA - LHCN-M2 [nTPM]":"46.6","Cell RNA - MCF7 [nTPM]":"59.2","Cell RNA - MOLT-4 [nTPM]":"71.5","Cell RNA - NB-4 [nTPM]":"87.2","Cell RNA - NTERA-2 [nTPM]":"36.7","Cell RNA - OE19 [nTPM]":"125.8","Cell RNA - PC-3 [nTPM]":"75.1","Cell RNA - REH [nTPM]":"39.1","Cell RNA - RH-30 [nTPM]":"93.5","Cell RNA - RPMI-8226 [nTPM]":"88.1","Cell RNA - RPTEC TERT1 [nTPM]":"89.9","Cell RNA - RT4 [nTPM]":"66.7","Cell RNA - SCLC-21H [nTPM]":"63.3","Cell RNA - SH-SY5Y [nTPM]":"50.1","Cell RNA - SiHa [nTPM]":"34.9","Cell RNA - SK-BR-3 [nTPM]":"37.3","Cell RNA - SK-MEL-30 [nTPM]":"75.4","Cell RNA - SuSa [nTPM]":"52.2","Cell RNA - T-47d [nTPM]":"158.0","Cell RNA - THP-1 [nTPM]":"70.4","Cell RNA - TIME [nTPM]":"41.6","Cell RNA - U-138 MG [nTPM]":"68.3","Cell RNA - U-2 OS [nTPM]":"62.3","Cell RNA - U-2197 [nTPM]":"52.4","Cell RNA - U-251 MG [nTPM]":"40.1","Cell RNA - U-266\/70 [nTPM]":"84.6","Cell RNA - U-266\/84 [nTPM]":"127.4","Cell RNA - U-698 [nTPM]":"31.0","Cell RNA - U-87 MG [nTPM]":"80.9","Cell RNA - U-937 [nTPM]":"55.3","Cell RNA - WM-115 [nTPM]":"47.5","Blood RNA - basophil [nTPM]":"23.3","Blood RNA - classical monocyte [nTPM]":"29.8","Blood RNA - eosinophil [nTPM]":"26.8","Blood RNA - gdT-cell [nTPM]":"19.7","Blood RNA - intermediate monocyte [nTPM]":"31.8","Blood RNA - MAIT T-cell [nTPM]":"20.5","Blood RNA - memory B-cell [nTPM]":"15.8","Blood RNA - memory CD4 T-cell [nTPM]":"15.8","Blood RNA - memory CD8 T-cell [nTPM]":"19.1","Blood RNA - myeloid DC [nTPM]":"33.6","Blood RNA - naive B-cell [nTPM]":"15.7","Blood RNA - naive CD4 T-cell [nTPM]":"15.7","Blood RNA - naive CD8 T-cell [nTPM]":"16.3","Blood RNA - neutrophil [nTPM]":"19.5","Blood RNA - NK-cell [nTPM]":"21.0","Blood RNA - non-classical monocyte [nTPM]":"22.5","Blood RNA - plasmacytoid DC [nTPM]":"23.6","Blood RNA - T-reg [nTPM]":"18.1","Blood RNA - total PBMC [nTPM]":"24.0","Brain RNA - amygdala [nTPM]":"24.0","Brain RNA - basal ganglia [nTPM]":"24.0","Brain RNA - cerebellum [nTPM]":"24.7","Brain RNA - cerebral cortex [nTPM]":"28.1","Brain RNA - hippocampal formation [nTPM]":"25.4","Brain RNA - hypothalamus [nTPM]":"23.9","Brain RNA - medulla oblongata [nTPM]":"27.8","Brain RNA - midbrain [nTPM]":"24.7","Brain RNA - pons [nTPM]":"28.1","Brain RNA - spinal cord [nTPM]":"23.8","Brain RNA - thalamus [nTPM]":"25.7","Brain RNA - white matter [nTPM]":"24.6","Single Cell Type RNA - Adipocytes [nTPM]":"15.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"24.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"49.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"17.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"33.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"89.4","Single Cell Type RNA - dendritic cells [nTPM]":"21.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"44.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.6","Single Cell Type RNA - Endothelial cells [nTPM]":"20.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.4","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"51.6","Single Cell Type RNA - Fibroblasts [nTPM]":"18.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.0","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"101.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.9","Single Cell Type RNA - Hepatocytes [nTPM]":"94.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"40.3","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.7","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"23.6","Single Cell Type RNA - Langerhans cells [nTPM]":"16.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.7","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"19.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"36.2","Single Cell Type RNA - Muller glia cells [nTPM]":"29.4","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.9","Single Cell Type RNA - Paneth cells [nTPM]":"32.4","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"25.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"94.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.6","Single Cell Type RNA - Spermatocytes [nTPM]":"46.7","Single Cell Type RNA - Spermatogonia [nTPM]":"31.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"77.2","Single Cell Type RNA - T-cells [nTPM]":"16.9","Single Cell Type RNA - Theca cells [nTPM]":"36.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"45.1","Single Cell Type RNA - Urothelial cells [nTPM]":"30.7"},{"Gene":"COCH","Gene synonym":["COCH-5B2","DFNA31","DFNA9"],"Ensembl":"ENSG00000100473","Gene description":"Cochlin","Uniprot":["O43405"],"Chromosome":"14","Position":"30874514-30895065","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"pancreas":"502.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"63.0","Horizontal cells":"84.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"71.3"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"memory B-cell":"38.3","naive B-cell":"17.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"B-cells":"38.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"95.7","Hep G2":"63.8","K-562":"129.1","NB-4":"105.5","SCLC-21H":"111.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"50.8"},"Antibody":["HPA065086"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA065086":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.2","Tissue RNA - adrenal gland [nTPM]":"3.7","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"71.3","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"20.9","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"19.0","Tissue RNA - colon [nTPM]":"3.2","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"6.2","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"5.6","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"11.0","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"502.0","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"48.3","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"12.1","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"73.4","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"15.2","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"23.0","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"35.3","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"21.8","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.1","Cell RNA - CACO-2 [nTPM]":"20.9","Cell RNA - CAPAN-2 [nTPM]":"1.2","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"22.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"10.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"95.7","Cell RNA - HEL [nTPM]":"18.1","Cell RNA - HeLa [nTPM]":"7.6","Cell RNA - Hep G2 [nTPM]":"63.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"7.3","Cell RNA - HSkMC [nTPM]":"1.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"39.9","Cell RNA - K-562 [nTPM]":"129.1","Cell RNA - Karpas-707 [nTPM]":"5.1","Cell RNA - LHCN-M2 [nTPM]":"1.6","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"9.2","Cell RNA - NB-4 [nTPM]":"105.5","Cell RNA - NTERA-2 [nTPM]":"11.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"3.7","Cell RNA - REH [nTPM]":"26.7","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"1.1","Cell RNA - RT4 [nTPM]":"3.4","Cell RNA - SCLC-21H [nTPM]":"111.8","Cell RNA - SH-SY5Y [nTPM]":"30.4","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"12.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"48.7","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"5.7","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"11.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"38.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"17.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"71.3","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"20.9","Brain RNA - hippocampal formation [nTPM]":"5.6","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"13.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"63.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.3","Single Cell Type RNA - Fibroblasts [nTPM]":"22.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.8","Single Cell Type RNA - Horizontal cells [nTPM]":"84.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"25.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"22.1","Single Cell Type RNA - Spermatogonia [nTPM]":"20.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"COL11A1","Gene synonym":["CO11A1","COLL6","DFNA37","STL2"],"Ensembl":"ENSG00000060718","Gene description":"Collagen type XI alpha 1 chain","Uniprot":["P12107"],"Chromosome":"1","Position":"102876467-103108872","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Cataract","Deafness","Disease variant","Dwarfism","Ectodermal dysplasia","Non-syndromic deafness","Stickler syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"20.1","retina":"9.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"83.9","Excitatory neurons":"99.5","Oligodendrocyte precursor cells":"557.4","Theca cells":"139.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"27.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"116.9","BJ":"43.2","BJ hTERT+ SV40 Large T+ RasG12V":"85.3","HBF TERT88":"48.7","HSkMC":"142.5","SuSa":"60.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058335"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"640000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA058335":"AB_2683682"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"2.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"116.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"4.6","Cell RNA - ASC TERT1 [nTPM]":"5.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"43.2","Cell RNA - BJ hTERT+ [nTPM]":"16.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"85.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"48.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"142.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"17.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"31.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"7.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"15.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"60.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"27.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"4.7","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"2.2","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"83.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"9.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"21.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"99.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"18.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"29.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"557.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"139.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"COL11A2","Gene synonym":["DFNA13","DFNB53","HKE5"],"Ensembl":"ENSG00000204248","Gene description":"Collagen type XI alpha 2 chain","Uniprot":["P13942"],"Chromosome":"6","Position":"33162681-33192499","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Dwarfism","Non-syndromic deafness","Stickler syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"pituitary gland":"23.5","testis":"8.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"8.5","Early spermatids":"10.8","Muller glia cells":"5.2","Oligodendrocytes":"6.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"melanoma":"13.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"23.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"8.1","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"10.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"COL13A1","Gene synonym":[],"Ensembl":"ENSG00000197467","Gene description":"Collagen type XIII alpha 1 chain","Uniprot":["Q5TAT6"],"Chromosome":"10","Position":"69801880-69964275","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Differentiation","Osteogenesis"],"Molecular function":["Developmental protein","Heparin-binding"],"Disease involvement":["Congenital myasthenic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"30.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"10.1","granulocytes":"20.3","Melanocytes":"5.4","Microglial cells":"6.5","NK-cells":"9.2","Smooth muscle cells":"5.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"63.6","BJ hTERT+":"61.6","hTERT-RPE1":"83.7","HUVEC TERT2":"102.2","PC-3":"93.1","TIME":"137.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050392"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050392":"AB_2681110"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"9.5","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"5.7","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"30.4","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"1.4","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"10.9","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"13.6","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"1.5","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"22.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"4.3","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"63.6","Cell RNA - BJ hTERT+ [nTPM]":"61.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.4","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"10.5","Cell RNA - fHDF\/TERT166 [nTPM]":"30.1","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"2.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"18.9","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"2.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.5","Cell RNA - hTERT-HME1 [nTPM]":"9.0","Cell RNA - hTERT-RPE1 [nTPM]":"83.7","Cell RNA - HUVEC TERT2 [nTPM]":"102.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"10.4","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"93.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"10.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"3.4","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"137.4","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"17.1","Cell RNA - U-2197 [nTPM]":"5.7","Cell RNA - U-251 MG [nTPM]":"45.7","Cell RNA - U-266\/70 [nTPM]":"13.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"37.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"51.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"9.5","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"1.4","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"20.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"COL18A1","Gene synonym":["KNO","KNO1","KS"],"Ensembl":"ENSG00000182871","Gene description":"Collagen type XVIII alpha 1 chain","Uniprot":["P39060"],"Chromosome":"21","Position":"45405165-45513720","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Glaucoma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"561.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"479.6","Sertoli cells":"223.5","Smooth muscle cells":"268.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"3.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"139.0","EFO-21":"309.4","NTERA-2":"170.6","RPTEC TERT1":"131.6","TIME":"186.0"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"cerebellum":"22.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030933","HPA036104"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"290000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA030933":null,"HPA036104":"AB_2674943"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Tissue RNA - adipose tissue [nTPM]":"136.4","Tissue RNA - adrenal gland [nTPM]":"87.6","Tissue RNA - amygdala [nTPM]":"14.5","Tissue RNA - appendix [nTPM]":"33.9","Tissue RNA - basal ganglia [nTPM]":"22.3","Tissue RNA - bone marrow [nTPM]":"15.9","Tissue RNA - breast [nTPM]":"97.1","Tissue RNA - cerebellum [nTPM]":"26.4","Tissue RNA - cerebral cortex [nTPM]":"21.8","Tissue RNA - cervix [nTPM]":"229.4","Tissue RNA - choroid plexus [nTPM]":"34.4","Tissue RNA - colon [nTPM]":"91.2","Tissue RNA - duodenum [nTPM]":"30.4","Tissue RNA - endometrium 1 [nTPM]":"135.6","Tissue RNA - epididymis [nTPM]":"35.4","Tissue RNA - esophagus [nTPM]":"50.1","Tissue RNA - fallopian tube [nTPM]":"118.3","Tissue RNA - gallbladder [nTPM]":"28.9","Tissue RNA - heart muscle [nTPM]":"122.2","Tissue RNA - hippocampal formation [nTPM]":"15.7","Tissue RNA - hypothalamus [nTPM]":"18.1","Tissue RNA - kidney [nTPM]":"218.2","Tissue RNA - liver [nTPM]":"561.9","Tissue RNA - lung [nTPM]":"83.2","Tissue RNA - lymph node [nTPM]":"19.8","Tissue RNA - medulla oblongata [nTPM]":"43.7","Tissue RNA - midbrain [nTPM]":"28.6","Tissue RNA - ovary [nTPM]":"257.3","Tissue RNA - pancreas [nTPM]":"102.3","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"106.5","Tissue RNA - placenta [nTPM]":"40.7","Tissue RNA - pons [nTPM]":"39.1","Tissue RNA - prostate [nTPM]":"91.0","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"35.8","Tissue RNA - seminal vesicle [nTPM]":"46.8","Tissue RNA - skeletal muscle [nTPM]":"26.5","Tissue RNA - skin 1 [nTPM]":"77.8","Tissue RNA - small intestine [nTPM]":"65.7","Tissue RNA - smooth muscle [nTPM]":"28.5","Tissue RNA - spinal cord [nTPM]":"26.6","Tissue RNA - spleen [nTPM]":"86.8","Tissue RNA - stomach 1 [nTPM]":"44.5","Tissue RNA - testis [nTPM]":"30.0","Tissue RNA - thalamus [nTPM]":"27.0","Tissue RNA - thymus [nTPM]":"9.0","Tissue RNA - thyroid gland [nTPM]":"101.1","Tissue RNA - tongue [nTPM]":"7.4","Tissue RNA - tonsil [nTPM]":"7.2","Tissue RNA - urinary bladder [nTPM]":"109.8","Tissue RNA - vagina [nTPM]":"112.2","Tissue RNA - white matter [nTPM]":"45.4","Cell RNA - A-431 [nTPM]":"10.5","Cell RNA - A549 [nTPM]":"84.0","Cell RNA - AF22 [nTPM]":"20.6","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"38.6","Cell RNA - ASC TERT1 [nTPM]":"31.9","Cell RNA - BEWO [nTPM]":"3.3","Cell RNA - BJ [nTPM]":"82.0","Cell RNA - BJ hTERT+ [nTPM]":"139.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.5","Cell RNA - CACO-2 [nTPM]":"48.8","Cell RNA - CAPAN-2 [nTPM]":"28.9","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"309.4","Cell RNA - fHDF\/TERT166 [nTPM]":"82.8","Cell RNA - GAMG [nTPM]":"21.6","Cell RNA - HaCaT [nTPM]":"37.9","Cell RNA - HAP1 [nTPM]":"4.6","Cell RNA - HBEC3-KT [nTPM]":"5.0","Cell RNA - HBF TERT88 [nTPM]":"7.4","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"20.0","Cell RNA - HEL [nTPM]":"47.9","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"69.6","Cell RNA - HHSteC [nTPM]":"37.3","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"4.4","Cell RNA - HSkMC [nTPM]":"37.6","Cell RNA - hTCEpi [nTPM]":"3.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.8","Cell RNA - hTERT-HME1 [nTPM]":"4.5","Cell RNA - hTERT-RPE1 [nTPM]":"8.5","Cell RNA - HUVEC TERT2 [nTPM]":"121.3","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"49.6","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"16.7","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"170.6","Cell RNA - OE19 [nTPM]":"3.2","Cell RNA - PC-3 [nTPM]":"30.7","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"12.6","Cell RNA - RPMI-8226 [nTPM]":"4.0","Cell RNA - RPTEC TERT1 [nTPM]":"131.6","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"22.8","Cell RNA - SH-SY5Y [nTPM]":"16.3","Cell RNA - SiHa [nTPM]":"7.6","Cell RNA - SK-BR-3 [nTPM]":"7.8","Cell RNA - SK-MEL-30 [nTPM]":"26.6","Cell RNA - SuSa [nTPM]":"73.0","Cell RNA - T-47d [nTPM]":"7.5","Cell RNA - THP-1 [nTPM]":"9.9","Cell RNA - TIME [nTPM]":"186.0","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"11.4","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"17.7","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"1.7","Cell RNA - WM-115 [nTPM]":"32.7","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"14.5","Brain RNA - basal ganglia [nTPM]":"22.3","Brain RNA - cerebellum [nTPM]":"26.4","Brain RNA - cerebral cortex [nTPM]":"21.8","Brain RNA - hippocampal formation [nTPM]":"15.7","Brain RNA - hypothalamus [nTPM]":"18.1","Brain RNA - medulla oblongata [nTPM]":"43.7","Brain RNA - midbrain [nTPM]":"28.6","Brain RNA - pons [nTPM]":"39.1","Brain RNA - spinal cord [nTPM]":"26.6","Brain RNA - thalamus [nTPM]":"27.0","Brain RNA - white matter [nTPM]":"45.4","Single Cell Type RNA - Adipocytes [nTPM]":"156.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"67.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"67.7","Single Cell Type RNA - Bipolar cells [nTPM]":"13.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"112.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"3.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"117.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"58.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"99.5","Single Cell Type RNA - Endothelial cells [nTPM]":"91.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"33.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"101.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"144.2","Single Cell Type RNA - granulocytes [nTPM]":"57.8","Single Cell Type RNA - Granulosa cells [nTPM]":"6.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"75.0","Single Cell Type RNA - Hepatocytes [nTPM]":"479.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"12.1","Single Cell Type RNA - Langerhans cells [nTPM]":"32.5","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"79.9","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"49.8","Single Cell Type RNA - Microglial cells [nTPM]":"82.4","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"141.9","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"126.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"72.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.3","Single Cell Type RNA - Sertoli cells [nTPM]":"223.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"138.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"268.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"47.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.6"},{"Gene":"COL25A1","Gene synonym":[],"Ensembl":"ENSG00000188517","Gene description":"Collagen type XXV alpha 1 chain","Uniprot":["Q9BXS0"],"Chromosome":"4","Position":"108808725-109302752","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Heparin-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"30.0","retina":"24.7","testis":"19.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"107.1","Inhibitory neurons":"275.3","Late spermatids":"39.2","Rod photoreceptor cells":"71.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"HeLa":"47.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029107"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA029107":"AB_10600802"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.1","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"30.0","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"17.8","Tissue RNA - hypothalamus [nTPM]":"13.7","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"7.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"24.7","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"6.9","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"19.1","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"2.8","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"2.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"3.2","Cell RNA - HEL [nTPM]":"5.9","Cell RNA - HeLa [nTPM]":"47.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"1.2","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"5.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"2.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"30.0","Brain RNA - hippocampal formation [nTPM]":"17.8","Brain RNA - hypothalamus [nTPM]":"13.7","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"6.9","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"8.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"107.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"275.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"39.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"71.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.6","Single Cell Type RNA - Spermatocytes [nTPM]":"7.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"COL2A1","Gene synonym":["AOM","SEDC","STL1"],"Ensembl":"ENSG00000139219","Gene description":"Collagen type II alpha 1 chain","Uniprot":["P02458"],"Chromosome":"12","Position":"47972967-48004554","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Cataract","Deafness","Disease variant","Dwarfism","FDA approved drug targets","Stickler syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"epididymis":"19.1","pituitary gland":"9.2","retina":"5.6","stomach 1":"12.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"15.4","Enteroendocrine cells":"43.9","Late spermatids":"9.7","Muller glia cells":"22.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"156.3","HAP1":"98.9","HEK 293":"36.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002214","HPA055753"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 17: Intestinal endocrine cells - Hormone signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB002214":"AB_563666","HPA055753":"AB_2682908"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"19.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"5.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"156.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"5.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"98.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"36.3","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"5.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.9","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"11.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"15.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"9.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"22.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"COL4A6","Gene synonym":[],"Ensembl":"ENSG00000197565","Gene description":"Collagen type IV alpha 6 chain","Uniprot":["Q14031"],"Chromosome":"X","Position":"108155607-108439497","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"32.6","urinary bladder":"40.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"24.5","Basal respiratory cells":"16.0","Cardiomyocytes":"13.1","Prostatic glandular cells":"12.1","Urothelial cells":"15.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"46.0","HeLa":"40.1","HHSteC":"59.2","hTERT-HME1":"44.1","HUVEC TERT2":"41.7","TIME":"94.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065393"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA065393":"AB_2685483"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"12.6","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"32.6","Tissue RNA - epididymis [nTPM]":"17.0","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"13.3","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"4.2","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"9.3","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"5.5","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"12.5","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"21.5","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"6.5","Tissue RNA - small intestine [nTPM]":"1.5","Tissue RNA - smooth muscle [nTPM]":"24.5","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"13.3","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"40.7","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"31.1","Cell RNA - AF22 [nTPM]":"9.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"24.2","Cell RNA - ASC TERT1 [nTPM]":"1.7","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"17.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"5.8","Cell RNA - HAP1 [nTPM]":"10.3","Cell RNA - HBEC3-KT [nTPM]":"46.0","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"8.8","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"40.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"59.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.6","Cell RNA - hTCEpi [nTPM]":"27.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.5","Cell RNA - hTERT-HME1 [nTPM]":"44.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"41.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"14.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.9","Cell RNA - RT4 [nTPM]":"3.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"18.2","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"94.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"5.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"15.2"},{"Gene":"COL6A3","Gene synonym":[],"Ensembl":"ENSG00000163359","Gene description":"Collagen type VI alpha 3 chain","Uniprot":["P12111"],"Chromosome":"2","Position":"237324003-237414207","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystonia","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"smooth muscle":"391.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"355.2","Fibroblasts":"567.9","Leydig cells":"315.1","Smooth muscle cells":"197.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"3311.7","ASC TERT1":"4227.5","BJ hTERT+":"1279.6","HSkMC":"2705.3"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"4.5"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"spinal cord":"12.0"},"Antibody":["HPA010007","HPA010080"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA010007":null,"HPA010080":"AB_1078550"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.57e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Tissue RNA - adipose tissue [nTPM]":"150.8","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"126.5","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"74.5","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"212.6","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"94.8","Tissue RNA - duodenum [nTPM]":"22.9","Tissue RNA - endometrium 1 [nTPM]":"156.3","Tissue RNA - epididymis [nTPM]":"10.2","Tissue RNA - esophagus [nTPM]":"44.1","Tissue RNA - fallopian tube [nTPM]":"91.8","Tissue RNA - gallbladder [nTPM]":"236.4","Tissue RNA - heart muscle [nTPM]":"61.2","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"10.3","Tissue RNA - lung [nTPM]":"65.8","Tissue RNA - lymph node [nTPM]":"30.7","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"123.8","Tissue RNA - pancreas [nTPM]":"21.1","Tissue RNA - parathyroid gland [nTPM]":"17.3","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"132.9","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"47.7","Tissue RNA - rectum [nTPM]":"51.7","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"45.2","Tissue RNA - seminal vesicle [nTPM]":"55.4","Tissue RNA - skeletal muscle [nTPM]":"32.5","Tissue RNA - skin 1 [nTPM]":"35.7","Tissue RNA - small intestine [nTPM]":"46.6","Tissue RNA - smooth muscle [nTPM]":"391.3","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"41.5","Tissue RNA - testis [nTPM]":"15.6","Tissue RNA - thalamus [nTPM]":"1.8","Tissue RNA - thymus [nTPM]":"24.8","Tissue RNA - thyroid gland [nTPM]":"38.1","Tissue RNA - tongue [nTPM]":"62.3","Tissue RNA - tonsil [nTPM]":"16.1","Tissue RNA - urinary bladder [nTPM]":"188.4","Tissue RNA - vagina [nTPM]":"62.7","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3311.7","Cell RNA - ASC TERT1 [nTPM]":"4227.5","Cell RNA - BEWO [nTPM]":"60.9","Cell RNA - BJ [nTPM]":"815.6","Cell RNA - BJ hTERT+ [nTPM]":"1279.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"167.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"188.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"4.5","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"818.7","Cell RNA - GAMG [nTPM]":"67.4","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.9","Cell RNA - HBF TERT88 [nTPM]":"98.8","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"669.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"2705.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"596.3","Cell RNA - hTERT-HME1 [nTPM]":"1.8","Cell RNA - hTERT-RPE1 [nTPM]":"7.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"6.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"17.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"2.9","Cell RNA - U-138 MG [nTPM]":"19.0","Cell RNA - U-2 OS [nTPM]":"45.1","Cell RNA - U-2197 [nTPM]":"27.6","Cell RNA - U-251 MG [nTPM]":"142.4","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"859.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.8","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"48.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"61.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"355.2","Single Cell Type RNA - Endothelial cells [nTPM]":"17.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.2","Single Cell Type RNA - Fibroblasts [nTPM]":"567.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"85.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.6","Single Cell Type RNA - Leydig cells [nTPM]":"315.1","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"72.9","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"2.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"103.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"197.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"61.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - T-cells [nTPM]":"9.3","Single Cell Type RNA - Theca cells [nTPM]":"48.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"COL8A2","Gene synonym":["FECD","FECD1","PPCD","PPCD2"],"Ensembl":"ENSG00000171812","Gene description":"Collagen type VIII alpha 2 chain","Uniprot":["P25067"],"Chromosome":"1","Position":"36095239-36125222","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Angiogenesis","Cell adhesion"],"Molecular function":null,"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"10.2","Cardiomyocytes":"13.5","Fibroblasts":"13.4","Macrophages":"6.8","Melanocytes":"7.2","Microglial cells":"8.4","Sertoli cells":"6.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"5.8","fHDF\/TERT166":"4.3","HHSteC":"14.1","hTERT-RPE1":"18.2","THP-1":"4.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"3.6"},"Antibody":["HPA049788"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA049788":"AB_2680882"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.44e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.26e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.35e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"5.6","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"9.0","Tissue RNA - choroid plexus [nTPM]":"18.3","Tissue RNA - colon [nTPM]":"5.9","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"5.7","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"5.8","Tissue RNA - fallopian tube [nTPM]":"4.2","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"1.1","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"12.8","Tissue RNA - pons [nTPM]":"7.1","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"7.4","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"8.5","Tissue RNA - stomach 1 [nTPM]":"9.1","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"7.5","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"3.5","Tissue RNA - urinary bladder [nTPM]":"13.3","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"5.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.9","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"4.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"14.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"18.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"4.7","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"7.1","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"5.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"13.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"6.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"COLQ","Gene synonym":["EAD"],"Ensembl":"ENSG00000206561","Gene description":"Collagen like tail subunit of asymmetric acetylcholinesterase","Uniprot":["Q9Y215"],"Chromosome":"3","Position":"15450133-15521751","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Neurotransmitter degradation"],"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"17.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"17.3","Excitatory neurons":"45.1","Inhibitory neurons":"46.3","Late spermatids":"16.6","NK-cells":"15.5","Oligodendrocyte precursor cells":"18.1","Oligodendrocytes":"18.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"MAIT T-cell":"60.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"34","RNA blood lineage specific nTPM":{"T-cells":"60.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"BEWO":"11.5","HDLM-2":"3.8","U-937":"5.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045876"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA045876":"AB_2679479"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-4"},"Tissue RNA - adipose tissue [nTPM]":"2.5","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"4.6","Tissue RNA - choroid plexus [nTPM]":"11.9","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"3.4","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"8.8","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"17.9","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"2.9","Tissue RNA - liver [nTPM]":"3.4","Tissue RNA - lung [nTPM]":"2.5","Tissue RNA - lymph node [nTPM]":"3.9","Tissue RNA - medulla oblongata [nTPM]":"4.8","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"3.6","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"2.8","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"10.8","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"5.0","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"5.1","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"2.2","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"11.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"3.8","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"5.2","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"60.9","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"5.3","Blood RNA - memory CD8 T-cell [nTPM]":"7.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"4.8","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"2.8","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"16.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"2.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"4.1","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"COQ2","Gene synonym":["CL640","FLJ26072"],"Ensembl":"ENSG00000173085","Gene description":"Coenzyme Q2, polyprenyltransferase","Uniprot":["Q96H96"],"Chromosome":"4","Position":"83261536-83284914","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Isoprene biosynthesis","Ubiquinone biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinsonism","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"37.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"50.7","Kupffer cells":"53.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056599","HPA068727"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA056599":"AB_2683184","HPA068727":"AB_2686022"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.0","Tissue RNA - adrenal gland [nTPM]":"17.0","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"11.8","Tissue RNA - breast [nTPM]":"5.8","Tissue RNA - cerebellum [nTPM]":"3.5","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"14.2","Tissue RNA - duodenum [nTPM]":"9.5","Tissue RNA - endometrium 1 [nTPM]":"6.3","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"4.3","Tissue RNA - heart muscle [nTPM]":"15.0","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"13.6","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"6.5","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"6.0","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"14.2","Tissue RNA - retina [nTPM]":"4.0","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"29.1","Tissue RNA - skin 1 [nTPM]":"10.8","Tissue RNA - small intestine [nTPM]":"9.1","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"10.1","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"37.5","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"6.5","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"26.1","Cell RNA - A549 [nTPM]":"14.7","Cell RNA - AF22 [nTPM]":"14.1","Cell RNA - AN3-CA [nTPM]":"27.4","Cell RNA - ASC diff [nTPM]":"10.5","Cell RNA - ASC TERT1 [nTPM]":"11.9","Cell RNA - BEWO [nTPM]":"9.7","Cell RNA - BJ [nTPM]":"16.1","Cell RNA - BJ hTERT+ [nTPM]":"27.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.4","Cell RNA - CACO-2 [nTPM]":"10.5","Cell RNA - CAPAN-2 [nTPM]":"38.7","Cell RNA - Daudi [nTPM]":"17.2","Cell RNA - EFO-21 [nTPM]":"11.7","Cell RNA - fHDF\/TERT166 [nTPM]":"28.4","Cell RNA - GAMG [nTPM]":"24.6","Cell RNA - HaCaT [nTPM]":"18.6","Cell RNA - HAP1 [nTPM]":"23.9","Cell RNA - HBEC3-KT [nTPM]":"26.0","Cell RNA - HBF TERT88 [nTPM]":"38.7","Cell RNA - HDLM-2 [nTPM]":"17.2","Cell RNA - HEK 293 [nTPM]":"14.8","Cell RNA - HEL [nTPM]":"15.3","Cell RNA - HeLa [nTPM]":"22.3","Cell RNA - Hep G2 [nTPM]":"15.4","Cell RNA - HHSteC [nTPM]":"11.7","Cell RNA - HL-60 [nTPM]":"31.3","Cell RNA - HMC-1 [nTPM]":"73.5","Cell RNA - HSkMC [nTPM]":"15.9","Cell RNA - hTCEpi [nTPM]":"16.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.2","Cell RNA - hTERT-HME1 [nTPM]":"24.8","Cell RNA - hTERT-RPE1 [nTPM]":"8.9","Cell RNA - HUVEC TERT2 [nTPM]":"30.7","Cell RNA - JURKAT [nTPM]":"9.7","Cell RNA - K-562 [nTPM]":"10.0","Cell RNA - Karpas-707 [nTPM]":"21.4","Cell RNA - LHCN-M2 [nTPM]":"29.3","Cell RNA - MCF7 [nTPM]":"27.4","Cell RNA - MOLT-4 [nTPM]":"8.6","Cell RNA - NB-4 [nTPM]":"21.7","Cell RNA - NTERA-2 [nTPM]":"10.9","Cell RNA - OE19 [nTPM]":"30.6","Cell RNA - PC-3 [nTPM]":"19.9","Cell RNA - REH [nTPM]":"14.1","Cell RNA - RH-30 [nTPM]":"11.4","Cell RNA - RPMI-8226 [nTPM]":"22.1","Cell RNA - RPTEC TERT1 [nTPM]":"45.4","Cell RNA - RT4 [nTPM]":"13.8","Cell RNA - SCLC-21H [nTPM]":"10.3","Cell RNA - SH-SY5Y [nTPM]":"6.3","Cell RNA - SiHa [nTPM]":"19.0","Cell RNA - SK-BR-3 [nTPM]":"24.5","Cell RNA - SK-MEL-30 [nTPM]":"9.2","Cell RNA - SuSa [nTPM]":"6.7","Cell RNA - T-47d [nTPM]":"15.4","Cell RNA - THP-1 [nTPM]":"18.8","Cell RNA - TIME [nTPM]":"21.0","Cell RNA - U-138 MG [nTPM]":"14.6","Cell RNA - U-2 OS [nTPM]":"14.6","Cell RNA - U-2197 [nTPM]":"11.1","Cell RNA - U-251 MG [nTPM]":"23.4","Cell RNA - U-266\/70 [nTPM]":"5.7","Cell RNA - U-266\/84 [nTPM]":"5.2","Cell RNA - U-698 [nTPM]":"10.2","Cell RNA - U-87 MG [nTPM]":"29.5","Cell RNA - U-937 [nTPM]":"36.8","Cell RNA - WM-115 [nTPM]":"20.2","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"28.8","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"26.8","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"6.2","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"21.1","Blood RNA - naive B-cell [nTPM]":"6.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"9.8","Blood RNA - NK-cell [nTPM]":"6.7","Blood RNA - non-classical monocyte [nTPM]":"33.5","Blood RNA - plasmacytoid DC [nTPM]":"11.2","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"13.6","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"3.5","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.2","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"10.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.4","Single Cell Type RNA - dendritic cells [nTPM]":"7.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"6.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.5","Single Cell Type RNA - Endothelial cells [nTPM]":"6.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"17.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"15.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"53.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"25.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"21.8","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.4","Single Cell Type RNA - Paneth cells [nTPM]":"15.4","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"4.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.7","Single Cell Type RNA - Spermatocytes [nTPM]":"18.1","Single Cell Type RNA - Spermatogonia [nTPM]":"19.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - T-cells [nTPM]":"9.6","Single Cell Type RNA - Theca cells [nTPM]":"35.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.7","Single Cell Type RNA - Urothelial cells [nTPM]":"12.9"},{"Gene":"COQ4","Gene synonym":["CGI-92"],"Ensembl":"ENSG00000167113","Gene description":"Coenzyme Q4","Uniprot":["Q9Y3A0"],"Chromosome":"9","Position":"128322544-128334072","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ubiquinone biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"202.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021406","HPA042945"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA021406":"AB_2670691","HPA042945":"AB_10961047"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.97e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.93e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.76e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Tissue RNA - adipose tissue [nTPM]":"23.9","Tissue RNA - adrenal gland [nTPM]":"52.9","Tissue RNA - amygdala [nTPM]":"33.9","Tissue RNA - appendix [nTPM]":"21.7","Tissue RNA - basal ganglia [nTPM]":"35.3","Tissue RNA - bone marrow [nTPM]":"19.7","Tissue RNA - breast [nTPM]":"28.2","Tissue RNA - cerebellum [nTPM]":"32.9","Tissue RNA - cerebral cortex [nTPM]":"43.6","Tissue RNA - cervix [nTPM]":"31.8","Tissue RNA - choroid plexus [nTPM]":"43.1","Tissue RNA - colon [nTPM]":"35.9","Tissue RNA - duodenum [nTPM]":"76.7","Tissue RNA - endometrium 1 [nTPM]":"24.9","Tissue RNA - epididymis [nTPM]":"19.4","Tissue RNA - esophagus [nTPM]":"62.1","Tissue RNA - fallopian tube [nTPM]":"51.8","Tissue RNA - gallbladder [nTPM]":"21.5","Tissue RNA - heart muscle [nTPM]":"39.6","Tissue RNA - hippocampal formation [nTPM]":"34.8","Tissue RNA - hypothalamus [nTPM]":"37.8","Tissue RNA - kidney [nTPM]":"62.9","Tissue RNA - liver [nTPM]":"63.8","Tissue RNA - lung [nTPM]":"25.0","Tissue RNA - lymph node [nTPM]":"24.4","Tissue RNA - medulla oblongata [nTPM]":"33.4","Tissue RNA - midbrain [nTPM]":"33.9","Tissue RNA - ovary [nTPM]":"30.5","Tissue RNA - pancreas [nTPM]":"64.1","Tissue RNA - parathyroid gland [nTPM]":"45.5","Tissue RNA - pituitary gland [nTPM]":"53.4","Tissue RNA - placenta [nTPM]":"17.6","Tissue RNA - pons [nTPM]":"33.2","Tissue RNA - prostate [nTPM]":"41.2","Tissue RNA - rectum [nTPM]":"23.7","Tissue RNA - retina [nTPM]":"22.3","Tissue RNA - salivary gland [nTPM]":"47.1","Tissue RNA - seminal vesicle [nTPM]":"28.3","Tissue RNA - skeletal muscle [nTPM]":"31.8","Tissue RNA - skin 1 [nTPM]":"56.4","Tissue RNA - small intestine [nTPM]":"54.1","Tissue RNA - smooth muscle [nTPM]":"15.4","Tissue RNA - spinal cord [nTPM]":"32.3","Tissue RNA - spleen [nTPM]":"27.5","Tissue RNA - stomach 1 [nTPM]":"39.5","Tissue RNA - testis [nTPM]":"22.6","Tissue RNA - thalamus [nTPM]":"34.3","Tissue RNA - thymus [nTPM]":"20.3","Tissue RNA - thyroid gland [nTPM]":"51.2","Tissue RNA - tongue [nTPM]":"22.6","Tissue RNA - tonsil [nTPM]":"22.9","Tissue RNA - urinary bladder [nTPM]":"31.1","Tissue RNA - vagina [nTPM]":"34.1","Tissue RNA - white matter [nTPM]":"36.0","Cell RNA - A-431 [nTPM]":"36.6","Cell RNA - A549 [nTPM]":"54.4","Cell RNA - AF22 [nTPM]":"31.5","Cell RNA - AN3-CA [nTPM]":"36.6","Cell RNA - ASC diff [nTPM]":"22.4","Cell RNA - ASC TERT1 [nTPM]":"31.2","Cell RNA - BEWO [nTPM]":"58.2","Cell RNA - BJ [nTPM]":"31.7","Cell RNA - BJ hTERT+ [nTPM]":"20.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.0","Cell RNA - CACO-2 [nTPM]":"48.4","Cell RNA - CAPAN-2 [nTPM]":"46.5","Cell RNA - Daudi [nTPM]":"48.6","Cell RNA - EFO-21 [nTPM]":"28.1","Cell RNA - fHDF\/TERT166 [nTPM]":"24.2","Cell RNA - GAMG [nTPM]":"31.6","Cell RNA - HaCaT [nTPM]":"99.9","Cell RNA - HAP1 [nTPM]":"27.0","Cell RNA - HBEC3-KT [nTPM]":"38.0","Cell RNA - HBF TERT88 [nTPM]":"14.6","Cell RNA - HDLM-2 [nTPM]":"25.1","Cell RNA - HEK 293 [nTPM]":"50.5","Cell RNA - HEL [nTPM]":"18.1","Cell RNA - HeLa [nTPM]":"112.9","Cell RNA - Hep G2 [nTPM]":"52.9","Cell RNA - HHSteC [nTPM]":"38.9","Cell RNA - HL-60 [nTPM]":"51.5","Cell RNA - HMC-1 [nTPM]":"27.0","Cell RNA - HSkMC [nTPM]":"37.4","Cell RNA - hTCEpi [nTPM]":"45.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.6","Cell RNA - hTERT-HME1 [nTPM]":"36.6","Cell RNA - hTERT-RPE1 [nTPM]":"21.9","Cell RNA - HUVEC TERT2 [nTPM]":"32.4","Cell RNA - JURKAT [nTPM]":"40.8","Cell RNA - K-562 [nTPM]":"121.1","Cell RNA - Karpas-707 [nTPM]":"31.5","Cell RNA - LHCN-M2 [nTPM]":"26.0","Cell RNA - MCF7 [nTPM]":"106.2","Cell RNA - MOLT-4 [nTPM]":"60.5","Cell RNA - NB-4 [nTPM]":"38.0","Cell RNA - NTERA-2 [nTPM]":"37.0","Cell RNA - OE19 [nTPM]":"75.1","Cell RNA - PC-3 [nTPM]":"60.7","Cell RNA - REH [nTPM]":"60.7","Cell RNA - RH-30 [nTPM]":"45.2","Cell RNA - RPMI-8226 [nTPM]":"91.0","Cell RNA - RPTEC TERT1 [nTPM]":"49.0","Cell RNA - RT4 [nTPM]":"36.9","Cell RNA - SCLC-21H [nTPM]":"58.8","Cell RNA - SH-SY5Y [nTPM]":"40.1","Cell RNA - SiHa [nTPM]":"64.7","Cell RNA - SK-BR-3 [nTPM]":"71.5","Cell RNA - SK-MEL-30 [nTPM]":"41.4","Cell RNA - SuSa [nTPM]":"13.8","Cell RNA - T-47d [nTPM]":"92.2","Cell RNA - THP-1 [nTPM]":"18.0","Cell RNA - TIME [nTPM]":"43.3","Cell RNA - U-138 MG [nTPM]":"38.0","Cell RNA - U-2 OS [nTPM]":"35.1","Cell RNA - U-2197 [nTPM]":"56.9","Cell RNA - U-251 MG [nTPM]":"43.9","Cell RNA - U-266\/70 [nTPM]":"53.4","Cell RNA - U-266\/84 [nTPM]":"50.4","Cell RNA - U-698 [nTPM]":"38.5","Cell RNA - U-87 MG [nTPM]":"47.4","Cell RNA - U-937 [nTPM]":"25.0","Cell RNA - WM-115 [nTPM]":"28.1","Blood RNA - basophil [nTPM]":"22.6","Blood RNA - classical monocyte [nTPM]":"31.1","Blood RNA - eosinophil [nTPM]":"19.0","Blood RNA - gdT-cell [nTPM]":"44.1","Blood RNA - intermediate monocyte [nTPM]":"36.4","Blood RNA - MAIT T-cell [nTPM]":"39.8","Blood RNA - memory B-cell [nTPM]":"39.9","Blood RNA - memory CD4 T-cell [nTPM]":"39.4","Blood RNA - memory CD8 T-cell [nTPM]":"44.1","Blood RNA - myeloid DC [nTPM]":"39.6","Blood RNA - naive B-cell [nTPM]":"34.4","Blood RNA - naive CD4 T-cell [nTPM]":"31.1","Blood RNA - naive CD8 T-cell [nTPM]":"38.2","Blood RNA - neutrophil [nTPM]":"3.8","Blood RNA - NK-cell [nTPM]":"35.5","Blood RNA - non-classical monocyte [nTPM]":"37.2","Blood RNA - plasmacytoid DC [nTPM]":"63.7","Blood RNA - T-reg [nTPM]":"34.5","Blood RNA - total PBMC [nTPM]":"29.9","Brain RNA - amygdala [nTPM]":"33.9","Brain RNA - basal ganglia [nTPM]":"35.3","Brain RNA - cerebellum [nTPM]":"32.9","Brain RNA - cerebral cortex [nTPM]":"43.6","Brain RNA - hippocampal formation [nTPM]":"34.8","Brain RNA - hypothalamus [nTPM]":"37.8","Brain RNA - medulla oblongata [nTPM]":"33.4","Brain RNA - midbrain [nTPM]":"33.9","Brain RNA - pons [nTPM]":"33.2","Brain RNA - spinal cord [nTPM]":"32.3","Brain RNA - thalamus [nTPM]":"34.3","Brain RNA - white matter [nTPM]":"36.0","Single Cell Type RNA - Adipocytes [nTPM]":"21.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.0","Single Cell Type RNA - Astrocytes [nTPM]":"25.8","Single Cell Type RNA - B-cells [nTPM]":"31.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Bipolar cells [nTPM]":"29.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"60.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"65.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"48.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"57.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"90.3","Single Cell Type RNA - dendritic cells [nTPM]":"36.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"70.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"142.8","Single Cell Type RNA - Ductal cells [nTPM]":"56.4","Single Cell Type RNA - Early spermatids [nTPM]":"15.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"139.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.8","Single Cell Type RNA - Endothelial cells [nTPM]":"25.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.8","Single Cell Type RNA - Erythroid cells [nTPM]":"36.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"63.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.5","Single Cell Type RNA - Fibroblasts [nTPM]":"32.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.2","Single Cell Type RNA - granulocytes [nTPM]":"36.8","Single Cell Type RNA - Granulosa cells [nTPM]":"37.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.0","Single Cell Type RNA - Hepatocytes [nTPM]":"77.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.8","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"65.6","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"26.7","Single Cell Type RNA - Langerhans cells [nTPM]":"23.9","Single Cell Type RNA - Late spermatids [nTPM]":"27.4","Single Cell Type RNA - Leydig cells [nTPM]":"30.1","Single Cell Type RNA - Macrophages [nTPM]":"24.0","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"27.2","Single Cell Type RNA - Muller glia cells [nTPM]":"37.4","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"46.1","Single Cell Type RNA - Paneth cells [nTPM]":"66.2","Single Cell Type RNA - Peritubular cells [nTPM]":"30.9","Single Cell Type RNA - Plasma cells [nTPM]":"60.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"185.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"202.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"161.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.4","Single Cell Type RNA - Spermatocytes [nTPM]":"47.2","Single Cell Type RNA - Spermatogonia [nTPM]":"31.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"79.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"47.2","Single Cell Type RNA - T-cells [nTPM]":"32.3","Single Cell Type RNA - Theca cells [nTPM]":"69.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"85.5","Single Cell Type RNA - Urothelial cells [nTPM]":"58.0"},{"Gene":"COQ5","Gene synonym":["MGC4767"],"Ensembl":"ENSG00000110871","Gene description":"Coenzyme Q5, methyltransferase","Uniprot":["Q5HYK3"],"Chromosome":"12","Position":"120503279-120534434","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Ubiquinone biosynthesis"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049487"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA049487":"AB_2680789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.7","Tissue RNA - adrenal gland [nTPM]":"29.9","Tissue RNA - amygdala [nTPM]":"22.3","Tissue RNA - appendix [nTPM]":"15.9","Tissue RNA - basal ganglia [nTPM]":"25.3","Tissue RNA - bone marrow [nTPM]":"11.3","Tissue RNA - breast [nTPM]":"24.1","Tissue RNA - cerebellum [nTPM]":"24.5","Tissue RNA - cerebral cortex [nTPM]":"29.0","Tissue RNA - cervix [nTPM]":"19.7","Tissue RNA - choroid plexus [nTPM]":"26.7","Tissue RNA - colon [nTPM]":"24.7","Tissue RNA - duodenum [nTPM]":"23.4","Tissue RNA - endometrium 1 [nTPM]":"17.9","Tissue RNA - epididymis [nTPM]":"23.0","Tissue RNA - esophagus [nTPM]":"20.4","Tissue RNA - fallopian tube [nTPM]":"22.2","Tissue RNA - gallbladder [nTPM]":"14.4","Tissue RNA - heart muscle [nTPM]":"40.7","Tissue RNA - hippocampal formation [nTPM]":"22.1","Tissue RNA - hypothalamus [nTPM]":"23.4","Tissue RNA - kidney [nTPM]":"38.9","Tissue RNA - liver [nTPM]":"60.7","Tissue RNA - lung [nTPM]":"15.4","Tissue RNA - lymph node [nTPM]":"23.3","Tissue RNA - medulla oblongata [nTPM]":"24.9","Tissue RNA - midbrain [nTPM]":"24.2","Tissue RNA - ovary [nTPM]":"20.5","Tissue RNA - pancreas [nTPM]":"20.6","Tissue RNA - parathyroid gland [nTPM]":"21.6","Tissue RNA - pituitary gland [nTPM]":"18.1","Tissue RNA - placenta [nTPM]":"23.3","Tissue RNA - pons [nTPM]":"24.8","Tissue RNA - prostate [nTPM]":"18.9","Tissue RNA - rectum [nTPM]":"24.7","Tissue RNA - retina [nTPM]":"26.3","Tissue RNA - salivary gland [nTPM]":"22.4","Tissue RNA - seminal vesicle [nTPM]":"15.8","Tissue RNA - skeletal muscle [nTPM]":"98.5","Tissue RNA - skin 1 [nTPM]":"17.6","Tissue RNA - small intestine [nTPM]":"20.0","Tissue RNA - smooth muscle [nTPM]":"18.2","Tissue RNA - spinal cord [nTPM]":"22.8","Tissue RNA - spleen [nTPM]":"21.1","Tissue RNA - stomach 1 [nTPM]":"19.3","Tissue RNA - testis [nTPM]":"24.7","Tissue RNA - thalamus [nTPM]":"24.3","Tissue RNA - thymus [nTPM]":"22.3","Tissue RNA - thyroid gland [nTPM]":"25.7","Tissue RNA - tongue [nTPM]":"69.2","Tissue RNA - tonsil [nTPM]":"23.4","Tissue RNA - urinary bladder [nTPM]":"17.2","Tissue RNA - vagina [nTPM]":"17.6","Tissue RNA - white matter [nTPM]":"29.5","Cell RNA - A-431 [nTPM]":"35.7","Cell RNA - A549 [nTPM]":"56.1","Cell RNA - AF22 [nTPM]":"49.2","Cell RNA - AN3-CA [nTPM]":"14.2","Cell RNA - ASC diff [nTPM]":"63.5","Cell RNA - ASC TERT1 [nTPM]":"48.5","Cell RNA - BEWO [nTPM]":"33.7","Cell RNA - BJ [nTPM]":"42.3","Cell RNA - BJ hTERT+ [nTPM]":"27.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.9","Cell RNA - CACO-2 [nTPM]":"22.5","Cell RNA - CAPAN-2 [nTPM]":"29.2","Cell RNA - Daudi [nTPM]":"35.6","Cell RNA - EFO-21 [nTPM]":"48.8","Cell RNA - fHDF\/TERT166 [nTPM]":"44.7","Cell RNA - GAMG [nTPM]":"29.9","Cell RNA - HaCaT [nTPM]":"37.7","Cell RNA - HAP1 [nTPM]":"44.2","Cell RNA - HBEC3-KT [nTPM]":"47.2","Cell RNA - HBF TERT88 [nTPM]":"43.3","Cell RNA - HDLM-2 [nTPM]":"45.4","Cell RNA - HEK 293 [nTPM]":"26.3","Cell RNA - HEL [nTPM]":"47.4","Cell RNA - HeLa [nTPM]":"35.0","Cell RNA - Hep G2 [nTPM]":"37.8","Cell RNA - HHSteC [nTPM]":"51.8","Cell RNA - HL-60 [nTPM]":"52.2","Cell RNA - HMC-1 [nTPM]":"28.7","Cell RNA - HSkMC [nTPM]":"46.8","Cell RNA - hTCEpi [nTPM]":"50.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.0","Cell RNA - hTERT-HME1 [nTPM]":"46.1","Cell RNA - hTERT-RPE1 [nTPM]":"66.0","Cell RNA - HUVEC TERT2 [nTPM]":"38.0","Cell RNA - JURKAT [nTPM]":"67.5","Cell RNA - K-562 [nTPM]":"47.4","Cell RNA - Karpas-707 [nTPM]":"25.3","Cell RNA - LHCN-M2 [nTPM]":"49.7","Cell RNA - MCF7 [nTPM]":"46.9","Cell RNA - MOLT-4 [nTPM]":"30.3","Cell RNA - NB-4 [nTPM]":"60.0","Cell RNA - NTERA-2 [nTPM]":"43.2","Cell RNA - OE19 [nTPM]":"25.4","Cell RNA - PC-3 [nTPM]":"43.2","Cell RNA - REH [nTPM]":"55.9","Cell RNA - RH-30 [nTPM]":"49.8","Cell RNA - RPMI-8226 [nTPM]":"52.0","Cell RNA - RPTEC TERT1 [nTPM]":"55.2","Cell RNA - RT4 [nTPM]":"26.7","Cell RNA - SCLC-21H [nTPM]":"37.0","Cell RNA - SH-SY5Y [nTPM]":"29.8","Cell RNA - SiHa [nTPM]":"30.7","Cell RNA - SK-BR-3 [nTPM]":"15.5","Cell RNA - SK-MEL-30 [nTPM]":"58.3","Cell RNA - SuSa [nTPM]":"51.2","Cell RNA - T-47d [nTPM]":"77.8","Cell RNA - THP-1 [nTPM]":"42.6","Cell RNA - TIME [nTPM]":"37.9","Cell RNA - U-138 MG [nTPM]":"29.1","Cell RNA - U-2 OS [nTPM]":"33.4","Cell RNA - U-2197 [nTPM]":"21.8","Cell RNA - U-251 MG [nTPM]":"28.5","Cell RNA - U-266\/70 [nTPM]":"53.9","Cell RNA - U-266\/84 [nTPM]":"48.5","Cell RNA - U-698 [nTPM]":"40.5","Cell RNA - U-87 MG [nTPM]":"33.3","Cell RNA - U-937 [nTPM]":"48.9","Cell RNA - WM-115 [nTPM]":"35.8","Blood RNA - basophil [nTPM]":"28.6","Blood RNA - classical monocyte [nTPM]":"44.3","Blood RNA - eosinophil [nTPM]":"32.3","Blood RNA - gdT-cell [nTPM]":"39.7","Blood RNA - intermediate monocyte [nTPM]":"44.9","Blood RNA - MAIT T-cell [nTPM]":"39.0","Blood RNA - memory B-cell [nTPM]":"45.6","Blood RNA - memory CD4 T-cell [nTPM]":"42.4","Blood RNA - memory CD8 T-cell [nTPM]":"43.2","Blood RNA - myeloid DC [nTPM]":"61.0","Blood RNA - naive B-cell [nTPM]":"52.7","Blood RNA - naive CD4 T-cell [nTPM]":"56.8","Blood RNA - naive CD8 T-cell [nTPM]":"45.5","Blood RNA - neutrophil [nTPM]":"9.3","Blood RNA - NK-cell [nTPM]":"60.6","Blood RNA - non-classical monocyte [nTPM]":"43.5","Blood RNA - plasmacytoid DC [nTPM]":"40.3","Blood RNA - T-reg [nTPM]":"57.2","Blood RNA - total PBMC [nTPM]":"54.4","Brain RNA - amygdala [nTPM]":"22.3","Brain RNA - basal ganglia [nTPM]":"25.3","Brain RNA - cerebellum [nTPM]":"24.5","Brain RNA - cerebral cortex [nTPM]":"29.0","Brain RNA - hippocampal formation [nTPM]":"22.1","Brain RNA - hypothalamus [nTPM]":"23.4","Brain RNA - medulla oblongata [nTPM]":"24.9","Brain RNA - midbrain [nTPM]":"24.2","Brain RNA - pons [nTPM]":"24.8","Brain RNA - spinal cord [nTPM]":"22.8","Brain RNA - thalamus [nTPM]":"24.3","Brain RNA - white matter [nTPM]":"29.5","Single Cell Type RNA - Adipocytes [nTPM]":"14.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"15.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"12.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"18.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"73.0","Single Cell Type RNA - dendritic cells [nTPM]":"12.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"32.3","Single Cell Type RNA - Early spermatids [nTPM]":"59.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"15.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"17.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.6","Single Cell Type RNA - Fibroblasts [nTPM]":"16.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.3","Single Cell Type RNA - granulocytes [nTPM]":"17.2","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"42.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"46.3","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.0","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"12.8","Single Cell Type RNA - Langerhans cells [nTPM]":"10.1","Single Cell Type RNA - Late spermatids [nTPM]":"23.1","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"13.6","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"29.0","Single Cell Type RNA - Muller glia cells [nTPM]":"18.0","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.0","Single Cell Type RNA - Paneth cells [nTPM]":"23.9","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"11.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.4","Single Cell Type RNA - Spermatocytes [nTPM]":"34.7","Single Cell Type RNA - Spermatogonia [nTPM]":"14.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"58.3","Single Cell Type RNA - T-cells [nTPM]":"15.0","Single Cell Type RNA - Theca cells [nTPM]":"32.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.9"},{"Gene":"COQ6","Gene synonym":["CGI-10"],"Ensembl":"ENSG00000119723","Gene description":"Coenzyme Q6, monooxygenase","Uniprot":["Q9Y2Z9"],"Chromosome":"14","Position":"73949926-73963670","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Ubiquinone biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Deafness","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"167.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051371"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051371":"AB_2681459"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.2","Tissue RNA - adrenal gland [nTPM]":"38.4","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"5.5","Tissue RNA - breast [nTPM]":"12.0","Tissue RNA - cerebellum [nTPM]":"10.9","Tissue RNA - cerebral cortex [nTPM]":"13.1","Tissue RNA - cervix [nTPM]":"12.1","Tissue RNA - choroid plexus [nTPM]":"15.5","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"11.3","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"10.5","Tissue RNA - gallbladder [nTPM]":"6.7","Tissue RNA - heart muscle [nTPM]":"32.0","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"11.1","Tissue RNA - kidney [nTPM]":"23.0","Tissue RNA - liver [nTPM]":"25.7","Tissue RNA - lung [nTPM]":"7.4","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"10.6","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"7.0","Tissue RNA - parathyroid gland [nTPM]":"25.1","Tissue RNA - pituitary gland [nTPM]":"15.9","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"10.6","Tissue RNA - prostate [nTPM]":"12.6","Tissue RNA - rectum [nTPM]":"9.5","Tissue RNA - retina [nTPM]":"5.8","Tissue RNA - salivary gland [nTPM]":"11.1","Tissue RNA - seminal vesicle [nTPM]":"9.9","Tissue RNA - skeletal muscle [nTPM]":"38.6","Tissue RNA - skin 1 [nTPM]":"9.3","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"10.7","Tissue RNA - spleen [nTPM]":"11.3","Tissue RNA - stomach 1 [nTPM]":"13.4","Tissue RNA - testis [nTPM]":"22.0","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"7.3","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"42.6","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"13.6","Tissue RNA - vagina [nTPM]":"10.5","Tissue RNA - white matter [nTPM]":"11.1","Cell RNA - A-431 [nTPM]":"12.2","Cell RNA - A549 [nTPM]":"21.7","Cell RNA - AF22 [nTPM]":"11.1","Cell RNA - AN3-CA [nTPM]":"25.7","Cell RNA - ASC diff [nTPM]":"13.2","Cell RNA - ASC TERT1 [nTPM]":"10.7","Cell RNA - BEWO [nTPM]":"15.4","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"13.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.4","Cell RNA - CACO-2 [nTPM]":"16.4","Cell RNA - CAPAN-2 [nTPM]":"21.0","Cell RNA - Daudi [nTPM]":"10.7","Cell RNA - EFO-21 [nTPM]":"13.7","Cell RNA - fHDF\/TERT166 [nTPM]":"15.3","Cell RNA - GAMG [nTPM]":"15.0","Cell RNA - HaCaT [nTPM]":"19.1","Cell RNA - HAP1 [nTPM]":"16.6","Cell RNA - HBEC3-KT [nTPM]":"14.8","Cell RNA - HBF TERT88 [nTPM]":"20.6","Cell RNA - HDLM-2 [nTPM]":"16.3","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"7.2","Cell RNA - HeLa [nTPM]":"12.8","Cell RNA - Hep G2 [nTPM]":"14.3","Cell RNA - HHSteC [nTPM]":"18.0","Cell RNA - HL-60 [nTPM]":"7.2","Cell RNA - HMC-1 [nTPM]":"24.9","Cell RNA - HSkMC [nTPM]":"18.1","Cell RNA - hTCEpi [nTPM]":"19.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.9","Cell RNA - hTERT-HME1 [nTPM]":"19.5","Cell RNA - hTERT-RPE1 [nTPM]":"14.1","Cell RNA - HUVEC TERT2 [nTPM]":"13.9","Cell RNA - JURKAT [nTPM]":"21.5","Cell RNA - K-562 [nTPM]":"6.4","Cell RNA - Karpas-707 [nTPM]":"9.6","Cell RNA - LHCN-M2 [nTPM]":"19.2","Cell RNA - MCF7 [nTPM]":"33.3","Cell RNA - MOLT-4 [nTPM]":"12.4","Cell RNA - NB-4 [nTPM]":"11.7","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"24.8","Cell RNA - PC-3 [nTPM]":"26.0","Cell RNA - REH [nTPM]":"11.7","Cell RNA - RH-30 [nTPM]":"14.1","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"22.9","Cell RNA - RT4 [nTPM]":"15.2","Cell RNA - SCLC-21H [nTPM]":"16.6","Cell RNA - SH-SY5Y [nTPM]":"8.8","Cell RNA - SiHa [nTPM]":"25.2","Cell RNA - SK-BR-3 [nTPM]":"21.5","Cell RNA - SK-MEL-30 [nTPM]":"14.6","Cell RNA - SuSa [nTPM]":"7.2","Cell RNA - T-47d [nTPM]":"36.4","Cell RNA - THP-1 [nTPM]":"13.3","Cell RNA - TIME [nTPM]":"9.4","Cell RNA - U-138 MG [nTPM]":"24.8","Cell RNA - U-2 OS [nTPM]":"22.9","Cell RNA - U-2197 [nTPM]":"19.0","Cell RNA - U-251 MG [nTPM]":"10.8","Cell RNA - U-266\/70 [nTPM]":"8.9","Cell RNA - U-266\/84 [nTPM]":"9.0","Cell RNA - U-698 [nTPM]":"9.0","Cell RNA - U-87 MG [nTPM]":"13.7","Cell RNA - U-937 [nTPM]":"10.6","Cell RNA - WM-115 [nTPM]":"17.1","Blood RNA - basophil [nTPM]":"5.4","Blood RNA - classical monocyte [nTPM]":"11.3","Blood RNA - eosinophil [nTPM]":"9.2","Blood RNA - gdT-cell [nTPM]":"11.3","Blood RNA - intermediate monocyte [nTPM]":"14.2","Blood RNA - MAIT T-cell [nTPM]":"11.3","Blood RNA - memory B-cell [nTPM]":"10.3","Blood RNA - memory CD4 T-cell [nTPM]":"11.2","Blood RNA - memory CD8 T-cell [nTPM]":"11.3","Blood RNA - myeloid DC [nTPM]":"12.1","Blood RNA - naive B-cell [nTPM]":"5.3","Blood RNA - naive CD4 T-cell [nTPM]":"15.6","Blood RNA - naive CD8 T-cell [nTPM]":"9.4","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"14.5","Blood RNA - non-classical monocyte [nTPM]":"13.1","Blood RNA - plasmacytoid DC [nTPM]":"8.9","Blood RNA - T-reg [nTPM]":"7.6","Blood RNA - total PBMC [nTPM]":"8.5","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"10.9","Brain RNA - cerebral cortex [nTPM]":"13.1","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"11.1","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"10.6","Brain RNA - pons [nTPM]":"10.6","Brain RNA - spinal cord [nTPM]":"10.7","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"11.1","Single Cell Type RNA - Adipocytes [nTPM]":"11.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"11.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"18.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"23.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.3","Single Cell Type RNA - dendritic cells [nTPM]":"4.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"10.8","Single Cell Type RNA - Early spermatids [nTPM]":"167.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.0","Single Cell Type RNA - Endothelial cells [nTPM]":"9.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.6","Single Cell Type RNA - Fibroblasts [nTPM]":"11.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.9","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"13.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"14.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.2","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"5.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"49.5","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"7.5","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"9.6","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.6","Single Cell Type RNA - Paneth cells [nTPM]":"8.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"10.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"41.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.5","Single Cell Type RNA - Spermatocytes [nTPM]":"24.7","Single Cell Type RNA - Spermatogonia [nTPM]":"21.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.8","Single Cell Type RNA - T-cells [nTPM]":"11.9","Single Cell Type RNA - Theca cells [nTPM]":"39.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.4","Single Cell Type RNA - Urothelial cells [nTPM]":"7.1"},{"Gene":"COQ7","Gene synonym":["CAT5","CLK-1"],"Ensembl":"ENSG00000167186","Gene description":"Coenzyme Q7, hydroxylase","Uniprot":["Q99807"],"Chromosome":"16","Position":"19067614-19080095","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubiquinone biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"40.4","neutrophil":"126.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"126.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067252","HPA071922"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA067252":"AB_2685813","HPA071922":"AB_2686473"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.23e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"10.7","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"11.2","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"10.9","Tissue RNA - cerebral cortex [nTPM]":"11.6","Tissue RNA - cervix [nTPM]":"10.8","Tissue RNA - choroid plexus [nTPM]":"12.5","Tissue RNA - colon [nTPM]":"14.1","Tissue RNA - duodenum [nTPM]":"12.4","Tissue RNA - endometrium 1 [nTPM]":"15.6","Tissue RNA - epididymis [nTPM]":"12.3","Tissue RNA - esophagus [nTPM]":"12.4","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"10.7","Tissue RNA - heart muscle [nTPM]":"23.4","Tissue RNA - hippocampal formation [nTPM]":"11.0","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"14.1","Tissue RNA - liver [nTPM]":"12.3","Tissue RNA - lung [nTPM]":"10.0","Tissue RNA - lymph node [nTPM]":"8.3","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"11.3","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"10.3","Tissue RNA - parathyroid gland [nTPM]":"24.4","Tissue RNA - pituitary gland [nTPM]":"9.7","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"11.1","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"14.0","Tissue RNA - salivary gland [nTPM]":"10.4","Tissue RNA - seminal vesicle [nTPM]":"14.7","Tissue RNA - skeletal muscle [nTPM]":"45.8","Tissue RNA - skin 1 [nTPM]":"7.9","Tissue RNA - small intestine [nTPM]":"11.8","Tissue RNA - smooth muscle [nTPM]":"11.6","Tissue RNA - spinal cord [nTPM]":"10.4","Tissue RNA - spleen [nTPM]":"10.0","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"20.9","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"16.2","Tissue RNA - tongue [nTPM]":"44.9","Tissue RNA - tonsil [nTPM]":"8.4","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"8.8","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"23.5","Cell RNA - A549 [nTPM]":"24.8","Cell RNA - AF22 [nTPM]":"21.1","Cell RNA - AN3-CA [nTPM]":"12.4","Cell RNA - ASC diff [nTPM]":"11.6","Cell RNA - ASC TERT1 [nTPM]":"12.2","Cell RNA - BEWO [nTPM]":"17.7","Cell RNA - BJ [nTPM]":"13.5","Cell RNA - BJ hTERT+ [nTPM]":"11.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.5","Cell RNA - CACO-2 [nTPM]":"15.9","Cell RNA - CAPAN-2 [nTPM]":"19.1","Cell RNA - Daudi [nTPM]":"17.8","Cell RNA - EFO-21 [nTPM]":"63.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.4","Cell RNA - GAMG [nTPM]":"19.4","Cell RNA - HaCaT [nTPM]":"24.5","Cell RNA - HAP1 [nTPM]":"29.6","Cell RNA - HBEC3-KT [nTPM]":"16.9","Cell RNA - HBF TERT88 [nTPM]":"13.0","Cell RNA - HDLM-2 [nTPM]":"15.2","Cell RNA - HEK 293 [nTPM]":"29.9","Cell RNA - HEL [nTPM]":"9.5","Cell RNA - HeLa [nTPM]":"22.8","Cell RNA - Hep G2 [nTPM]":"49.3","Cell RNA - HHSteC [nTPM]":"14.4","Cell RNA - HL-60 [nTPM]":"22.9","Cell RNA - HMC-1 [nTPM]":"20.1","Cell RNA - HSkMC [nTPM]":"10.3","Cell RNA - hTCEpi [nTPM]":"14.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.8","Cell RNA - hTERT-HME1 [nTPM]":"12.2","Cell RNA - hTERT-RPE1 [nTPM]":"14.8","Cell RNA - HUVEC TERT2 [nTPM]":"14.8","Cell RNA - JURKAT [nTPM]":"20.9","Cell RNA - K-562 [nTPM]":"26.4","Cell RNA - Karpas-707 [nTPM]":"16.2","Cell RNA - LHCN-M2 [nTPM]":"12.9","Cell RNA - MCF7 [nTPM]":"42.4","Cell RNA - MOLT-4 [nTPM]":"24.0","Cell RNA - NB-4 [nTPM]":"18.4","Cell RNA - NTERA-2 [nTPM]":"16.1","Cell RNA - OE19 [nTPM]":"9.1","Cell RNA - PC-3 [nTPM]":"13.1","Cell RNA - REH [nTPM]":"29.0","Cell RNA - RH-30 [nTPM]":"23.3","Cell RNA - RPMI-8226 [nTPM]":"22.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.7","Cell RNA - RT4 [nTPM]":"15.5","Cell RNA - SCLC-21H [nTPM]":"30.4","Cell RNA - SH-SY5Y [nTPM]":"17.4","Cell RNA - SiHa [nTPM]":"12.6","Cell RNA - SK-BR-3 [nTPM]":"27.4","Cell RNA - SK-MEL-30 [nTPM]":"16.2","Cell RNA - SuSa [nTPM]":"10.2","Cell RNA - T-47d [nTPM]":"25.2","Cell RNA - THP-1 [nTPM]":"30.7","Cell RNA - TIME [nTPM]":"16.3","Cell RNA - U-138 MG [nTPM]":"19.0","Cell RNA - U-2 OS [nTPM]":"10.9","Cell RNA - U-2197 [nTPM]":"14.1","Cell RNA - U-251 MG [nTPM]":"19.7","Cell RNA - U-266\/70 [nTPM]":"15.0","Cell RNA - U-266\/84 [nTPM]":"26.2","Cell RNA - U-698 [nTPM]":"19.7","Cell RNA - U-87 MG [nTPM]":"20.4","Cell RNA - U-937 [nTPM]":"13.1","Cell RNA - WM-115 [nTPM]":"12.5","Blood RNA - basophil [nTPM]":"40.4","Blood RNA - classical monocyte [nTPM]":"11.4","Blood RNA - eosinophil [nTPM]":"17.8","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"10.6","Blood RNA - MAIT T-cell [nTPM]":"9.4","Blood RNA - memory B-cell [nTPM]":"16.3","Blood RNA - memory CD4 T-cell [nTPM]":"8.9","Blood RNA - memory CD8 T-cell [nTPM]":"8.7","Blood RNA - myeloid DC [nTPM]":"12.6","Blood RNA - naive B-cell [nTPM]":"15.3","Blood RNA - naive CD4 T-cell [nTPM]":"12.2","Blood RNA - naive CD8 T-cell [nTPM]":"10.8","Blood RNA - neutrophil [nTPM]":"126.5","Blood RNA - NK-cell [nTPM]":"12.9","Blood RNA - non-classical monocyte [nTPM]":"12.3","Blood RNA - plasmacytoid DC [nTPM]":"15.6","Blood RNA - T-reg [nTPM]":"6.2","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"10.7","Brain RNA - basal ganglia [nTPM]":"11.2","Brain RNA - cerebellum [nTPM]":"10.9","Brain RNA - cerebral cortex [nTPM]":"11.6","Brain RNA - hippocampal formation [nTPM]":"11.0","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"11.3","Brain RNA - pons [nTPM]":"11.1","Brain RNA - spinal cord [nTPM]":"10.4","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"13.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"35.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"31.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"14.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.2","Single Cell Type RNA - dendritic cells [nTPM]":"28.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Ductal cells [nTPM]":"25.2","Single Cell Type RNA - Early spermatids [nTPM]":"14.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.2","Single Cell Type RNA - Endothelial cells [nTPM]":"16.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.2","Single Cell Type RNA - granulocytes [nTPM]":"25.4","Single Cell Type RNA - Granulosa cells [nTPM]":"31.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"11.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.3","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.0","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"29.4","Single Cell Type RNA - Langerhans cells [nTPM]":"12.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"18.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"11.6","Single Cell Type RNA - Muller glia cells [nTPM]":"39.5","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.4","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"11.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"71.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.2","Single Cell Type RNA - Spermatocytes [nTPM]":"81.3","Single Cell Type RNA - Spermatogonia [nTPM]":"53.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.2","Single Cell Type RNA - T-cells [nTPM]":"23.9","Single Cell Type RNA - Theca cells [nTPM]":"38.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.8","Single Cell Type RNA - Urothelial cells [nTPM]":"24.0"},{"Gene":"COQ8A","Gene synonym":["ADCK3","CABC1","COQ8","SCAR9"],"Ensembl":"ENSG00000163050","Gene description":"Coenzyme Q8A","Uniprot":["Q8NI60"],"Chromosome":"1","Position":"226940286-226987544","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubiquinone biosynthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"skeletal muscle":"1165.1","tongue":"484.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"21.9","Collecting duct cells":"33.1","Ductal cells":"21.2","Exocrine glandular cells":"32.7","Proximal tubular cells":"24.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"82.0","RPMI-8226":"78.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061662"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA061662":"AB_2684578"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"63.9","Tissue RNA - adrenal gland [nTPM]":"123.8","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"10.3","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"26.1","Tissue RNA - breast [nTPM]":"35.8","Tissue RNA - cerebellum [nTPM]":"17.3","Tissue RNA - cerebral cortex [nTPM]":"8.1","Tissue RNA - cervix [nTPM]":"16.5","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"30.8","Tissue RNA - duodenum [nTPM]":"29.9","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"32.2","Tissue RNA - fallopian tube [nTPM]":"24.6","Tissue RNA - gallbladder [nTPM]":"19.7","Tissue RNA - heart muscle [nTPM]":"123.5","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"14.4","Tissue RNA - liver [nTPM]":"35.7","Tissue RNA - lung [nTPM]":"9.6","Tissue RNA - lymph node [nTPM]":"12.7","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"34.1","Tissue RNA - pancreas [nTPM]":"93.8","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"18.5","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"32.7","Tissue RNA - seminal vesicle [nTPM]":"11.7","Tissue RNA - skeletal muscle [nTPM]":"1165.1","Tissue RNA - skin 1 [nTPM]":"25.1","Tissue RNA - small intestine [nTPM]":"18.5","Tissue RNA - smooth muscle [nTPM]":"7.2","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"14.4","Tissue RNA - stomach 1 [nTPM]":"52.8","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"484.7","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"40.8","Tissue RNA - vagina [nTPM]":"13.4","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"14.4","Cell RNA - AF22 [nTPM]":"3.3","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"11.4","Cell RNA - ASC TERT1 [nTPM]":"7.3","Cell RNA - BEWO [nTPM]":"57.7","Cell RNA - BJ [nTPM]":"3.6","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.9","Cell RNA - CACO-2 [nTPM]":"23.0","Cell RNA - CAPAN-2 [nTPM]":"12.8","Cell RNA - Daudi [nTPM]":"24.5","Cell RNA - EFO-21 [nTPM]":"17.9","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"2.6","Cell RNA - HaCaT [nTPM]":"9.2","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"8.2","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"25.5","Cell RNA - HEK 293 [nTPM]":"82.0","Cell RNA - HEL [nTPM]":"16.7","Cell RNA - HeLa [nTPM]":"11.2","Cell RNA - Hep G2 [nTPM]":"38.8","Cell RNA - HHSteC [nTPM]":"2.5","Cell RNA - HL-60 [nTPM]":"25.8","Cell RNA - HMC-1 [nTPM]":"9.3","Cell RNA - HSkMC [nTPM]":"14.2","Cell RNA - hTCEpi [nTPM]":"12.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.0","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"2.5","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"29.4","Cell RNA - Karpas-707 [nTPM]":"19.4","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"15.2","Cell RNA - NB-4 [nTPM]":"37.3","Cell RNA - NTERA-2 [nTPM]":"15.5","Cell RNA - OE19 [nTPM]":"62.8","Cell RNA - PC-3 [nTPM]":"29.5","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"17.1","Cell RNA - RPMI-8226 [nTPM]":"78.6","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"5.9","Cell RNA - SCLC-21H [nTPM]":"59.9","Cell RNA - SH-SY5Y [nTPM]":"24.2","Cell RNA - SiHa [nTPM]":"7.3","Cell RNA - SK-BR-3 [nTPM]":"28.7","Cell RNA - SK-MEL-30 [nTPM]":"20.6","Cell RNA - SuSa [nTPM]":"3.4","Cell RNA - T-47d [nTPM]":"15.1","Cell RNA - THP-1 [nTPM]":"34.8","Cell RNA - TIME [nTPM]":"2.5","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"8.2","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"43.0","Cell RNA - U-266\/84 [nTPM]":"40.5","Cell RNA - U-698 [nTPM]":"13.1","Cell RNA - U-87 MG [nTPM]":"5.3","Cell RNA - U-937 [nTPM]":"29.3","Cell RNA - WM-115 [nTPM]":"6.0","Blood RNA - basophil [nTPM]":"47.7","Blood RNA - classical monocyte [nTPM]":"23.5","Blood RNA - eosinophil [nTPM]":"68.4","Blood RNA - gdT-cell [nTPM]":"15.8","Blood RNA - intermediate monocyte [nTPM]":"17.1","Blood RNA - MAIT T-cell [nTPM]":"15.3","Blood RNA - memory B-cell [nTPM]":"22.2","Blood RNA - memory CD4 T-cell [nTPM]":"15.8","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"18.6","Blood RNA - naive B-cell [nTPM]":"26.8","Blood RNA - naive CD4 T-cell [nTPM]":"21.5","Blood RNA - naive CD8 T-cell [nTPM]":"17.0","Blood RNA - neutrophil [nTPM]":"43.1","Blood RNA - NK-cell [nTPM]":"21.2","Blood RNA - non-classical monocyte [nTPM]":"13.6","Blood RNA - plasmacytoid DC [nTPM]":"8.1","Blood RNA - T-reg [nTPM]":"21.5","Blood RNA - total PBMC [nTPM]":"26.0","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"17.3","Brain RNA - cerebral cortex [nTPM]":"8.1","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"11.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.2","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"21.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.6","Single Cell Type RNA - granulocytes [nTPM]":"13.9","Single Cell Type RNA - Granulosa cells [nTPM]":"9.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"6.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"11.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - T-cells [nTPM]":"5.2","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"COQ9","Gene synonym":["C16orf49","DKFZP434K046"],"Ensembl":"ENSG00000088682","Gene description":"Coenzyme Q9","Uniprot":["O75208"],"Chromosome":"16","Position":"57447425-57461270","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ubiquinone biosynthesis"],"Molecular function":null,"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"255.4","tongue":"241.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"217.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040918"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040918":"AB_10794154"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.03e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.3","Tissue RNA - adrenal gland [nTPM]":"44.7","Tissue RNA - amygdala [nTPM]":"21.7","Tissue RNA - appendix [nTPM]":"15.1","Tissue RNA - basal ganglia [nTPM]":"22.7","Tissue RNA - bone marrow [nTPM]":"10.6","Tissue RNA - breast [nTPM]":"18.0","Tissue RNA - cerebellum [nTPM]":"23.4","Tissue RNA - cerebral cortex [nTPM]":"26.1","Tissue RNA - cervix [nTPM]":"19.6","Tissue RNA - choroid plexus [nTPM]":"38.4","Tissue RNA - colon [nTPM]":"48.6","Tissue RNA - duodenum [nTPM]":"47.3","Tissue RNA - endometrium 1 [nTPM]":"16.8","Tissue RNA - epididymis [nTPM]":"16.6","Tissue RNA - esophagus [nTPM]":"40.0","Tissue RNA - fallopian tube [nTPM]":"24.0","Tissue RNA - gallbladder [nTPM]":"19.4","Tissue RNA - heart muscle [nTPM]":"139.7","Tissue RNA - hippocampal formation [nTPM]":"21.2","Tissue RNA - hypothalamus [nTPM]":"22.1","Tissue RNA - kidney [nTPM]":"61.3","Tissue RNA - liver [nTPM]":"53.2","Tissue RNA - lung [nTPM]":"14.4","Tissue RNA - lymph node [nTPM]":"15.6","Tissue RNA - medulla oblongata [nTPM]":"21.5","Tissue RNA - midbrain [nTPM]":"21.8","Tissue RNA - ovary [nTPM]":"16.6","Tissue RNA - pancreas [nTPM]":"27.9","Tissue RNA - parathyroid gland [nTPM]":"79.7","Tissue RNA - pituitary gland [nTPM]":"14.9","Tissue RNA - placenta [nTPM]":"16.7","Tissue RNA - pons [nTPM]":"20.7","Tissue RNA - prostate [nTPM]":"26.2","Tissue RNA - rectum [nTPM]":"38.2","Tissue RNA - retina [nTPM]":"11.8","Tissue RNA - salivary gland [nTPM]":"44.1","Tissue RNA - seminal vesicle [nTPM]":"28.8","Tissue RNA - skeletal muscle [nTPM]":"255.4","Tissue RNA - skin 1 [nTPM]":"25.2","Tissue RNA - small intestine [nTPM]":"41.8","Tissue RNA - smooth muscle [nTPM]":"28.3","Tissue RNA - spinal cord [nTPM]":"21.3","Tissue RNA - spleen [nTPM]":"12.2","Tissue RNA - stomach 1 [nTPM]":"35.3","Tissue RNA - testis [nTPM]":"23.8","Tissue RNA - thalamus [nTPM]":"24.3","Tissue RNA - thymus [nTPM]":"18.7","Tissue RNA - thyroid gland [nTPM]":"29.2","Tissue RNA - tongue [nTPM]":"241.0","Tissue RNA - tonsil [nTPM]":"17.3","Tissue RNA - urinary bladder [nTPM]":"38.2","Tissue RNA - vagina [nTPM]":"21.6","Tissue RNA - white matter [nTPM]":"21.7","Cell RNA - A-431 [nTPM]":"33.6","Cell RNA - A549 [nTPM]":"67.2","Cell RNA - AF22 [nTPM]":"18.3","Cell RNA - AN3-CA [nTPM]":"45.8","Cell RNA - ASC diff [nTPM]":"36.0","Cell RNA - ASC TERT1 [nTPM]":"27.3","Cell RNA - BEWO [nTPM]":"21.3","Cell RNA - BJ [nTPM]":"31.9","Cell RNA - BJ hTERT+ [nTPM]":"25.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.9","Cell RNA - CACO-2 [nTPM]":"41.2","Cell RNA - CAPAN-2 [nTPM]":"43.0","Cell RNA - Daudi [nTPM]":"40.3","Cell RNA - EFO-21 [nTPM]":"59.0","Cell RNA - fHDF\/TERT166 [nTPM]":"28.8","Cell RNA - GAMG [nTPM]":"34.3","Cell RNA - HaCaT [nTPM]":"70.5","Cell RNA - HAP1 [nTPM]":"52.8","Cell RNA - HBEC3-KT [nTPM]":"56.6","Cell RNA - HBF TERT88 [nTPM]":"28.3","Cell RNA - HDLM-2 [nTPM]":"21.4","Cell RNA - HEK 293 [nTPM]":"49.3","Cell RNA - HEL [nTPM]":"27.7","Cell RNA - HeLa [nTPM]":"44.2","Cell RNA - Hep G2 [nTPM]":"66.1","Cell RNA - HHSteC [nTPM]":"39.8","Cell RNA - HL-60 [nTPM]":"36.1","Cell RNA - HMC-1 [nTPM]":"44.4","Cell RNA - HSkMC [nTPM]":"45.6","Cell RNA - hTCEpi [nTPM]":"73.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.9","Cell RNA - hTERT-HME1 [nTPM]":"68.1","Cell RNA - hTERT-RPE1 [nTPM]":"29.8","Cell RNA - HUVEC TERT2 [nTPM]":"51.1","Cell RNA - JURKAT [nTPM]":"35.6","Cell RNA - K-562 [nTPM]":"54.7","Cell RNA - Karpas-707 [nTPM]":"18.1","Cell RNA - LHCN-M2 [nTPM]":"27.4","Cell RNA - MCF7 [nTPM]":"48.6","Cell RNA - MOLT-4 [nTPM]":"30.5","Cell RNA - NB-4 [nTPM]":"26.8","Cell RNA - NTERA-2 [nTPM]":"29.6","Cell RNA - OE19 [nTPM]":"74.4","Cell RNA - PC-3 [nTPM]":"90.6","Cell RNA - REH [nTPM]":"60.8","Cell RNA - RH-30 [nTPM]":"58.7","Cell RNA - RPMI-8226 [nTPM]":"104.8","Cell RNA - RPTEC TERT1 [nTPM]":"71.3","Cell RNA - RT4 [nTPM]":"37.4","Cell RNA - SCLC-21H [nTPM]":"56.3","Cell RNA - SH-SY5Y [nTPM]":"56.7","Cell RNA - SiHa [nTPM]":"108.4","Cell RNA - SK-BR-3 [nTPM]":"103.8","Cell RNA - SK-MEL-30 [nTPM]":"54.9","Cell RNA - SuSa [nTPM]":"16.1","Cell RNA - T-47d [nTPM]":"59.4","Cell RNA - THP-1 [nTPM]":"39.5","Cell RNA - TIME [nTPM]":"34.4","Cell RNA - U-138 MG [nTPM]":"32.4","Cell RNA - U-2 OS [nTPM]":"38.9","Cell RNA - U-2197 [nTPM]":"34.8","Cell RNA - U-251 MG [nTPM]":"40.4","Cell RNA - U-266\/70 [nTPM]":"42.9","Cell RNA - U-266\/84 [nTPM]":"29.5","Cell RNA - U-698 [nTPM]":"48.0","Cell RNA - U-87 MG [nTPM]":"44.4","Cell RNA - U-937 [nTPM]":"51.2","Cell RNA - WM-115 [nTPM]":"37.3","Blood RNA - basophil [nTPM]":"21.0","Blood RNA - classical monocyte [nTPM]":"28.2","Blood RNA - eosinophil [nTPM]":"23.0","Blood RNA - gdT-cell [nTPM]":"19.5","Blood RNA - intermediate monocyte [nTPM]":"36.6","Blood RNA - MAIT T-cell [nTPM]":"20.1","Blood RNA - memory B-cell [nTPM]":"18.8","Blood RNA - memory CD4 T-cell [nTPM]":"16.6","Blood RNA - memory CD8 T-cell [nTPM]":"17.1","Blood RNA - myeloid DC [nTPM]":"34.4","Blood RNA - naive B-cell [nTPM]":"19.1","Blood RNA - naive CD4 T-cell [nTPM]":"17.7","Blood RNA - naive CD8 T-cell [nTPM]":"26.0","Blood RNA - neutrophil [nTPM]":"8.9","Blood RNA - NK-cell [nTPM]":"24.0","Blood RNA - non-classical monocyte [nTPM]":"38.2","Blood RNA - plasmacytoid DC [nTPM]":"21.5","Blood RNA - T-reg [nTPM]":"25.5","Blood RNA - total PBMC [nTPM]":"21.9","Brain RNA - amygdala [nTPM]":"21.7","Brain RNA - basal ganglia [nTPM]":"22.7","Brain RNA - cerebellum [nTPM]":"23.4","Brain RNA - cerebral cortex [nTPM]":"26.1","Brain RNA - hippocampal formation [nTPM]":"21.2","Brain RNA - hypothalamus [nTPM]":"22.1","Brain RNA - medulla oblongata [nTPM]":"21.5","Brain RNA - midbrain [nTPM]":"21.8","Brain RNA - pons [nTPM]":"20.7","Brain RNA - spinal cord [nTPM]":"21.3","Brain RNA - thalamus [nTPM]":"24.3","Brain RNA - white matter [nTPM]":"21.7","Single Cell Type RNA - Adipocytes [nTPM]":"17.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.9","Single Cell Type RNA - Astrocytes [nTPM]":"37.9","Single Cell Type RNA - B-cells [nTPM]":"15.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"55.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"16.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"79.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"28.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"74.7","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"68.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"217.2","Single Cell Type RNA - Ductal cells [nTPM]":"53.9","Single Cell Type RNA - Early spermatids [nTPM]":"37.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.3","Single Cell Type RNA - Endothelial cells [nTPM]":"17.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.6","Single Cell Type RNA - Erythroid cells [nTPM]":"21.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.6","Single Cell Type RNA - Fibroblasts [nTPM]":"20.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.0","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"40.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.5","Single Cell Type RNA - Hepatocytes [nTPM]":"53.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.8","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.6","Single Cell Type RNA - Ionocytes [nTPM]":"83.4","Single Cell Type RNA - Kupffer cells [nTPM]":"16.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.4","Single Cell Type RNA - Late spermatids [nTPM]":"28.4","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"14.1","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"22.7","Single Cell Type RNA - Muller glia cells [nTPM]":"29.1","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.2","Single Cell Type RNA - Paneth cells [nTPM]":"37.0","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"15.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"90.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"114.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.8","Single Cell Type RNA - Spermatocytes [nTPM]":"66.0","Single Cell Type RNA - Spermatogonia [nTPM]":"38.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"78.7","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"91.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"70.2","Single Cell Type RNA - Urothelial cells [nTPM]":"18.4"},{"Gene":"COX6A1","Gene synonym":["COX6A"],"Ensembl":"ENSG00000111775","Gene description":"Cytochrome c oxidase subunit 6A1","Uniprot":["P12074"],"Chromosome":"12","Position":"120438090-120440737","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Charcot-Marie-Tooth disease","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062394"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"85000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA062394":"AB_2684749"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.50e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"353.0","Tissue RNA - adrenal gland [nTPM]":"396.5","Tissue RNA - amygdala [nTPM]":"1004.7","Tissue RNA - appendix [nTPM]":"203.3","Tissue RNA - basal ganglia [nTPM]":"1040.0","Tissue RNA - bone marrow [nTPM]":"368.0","Tissue RNA - breast [nTPM]":"321.3","Tissue RNA - cerebellum [nTPM]":"1052.0","Tissue RNA - cerebral cortex [nTPM]":"1305.8","Tissue RNA - cervix [nTPM]":"265.4","Tissue RNA - choroid plexus [nTPM]":"959.8","Tissue RNA - colon [nTPM]":"597.1","Tissue RNA - duodenum [nTPM]":"611.5","Tissue RNA - endometrium 1 [nTPM]":"248.1","Tissue RNA - epididymis [nTPM]":"273.9","Tissue RNA - esophagus [nTPM]":"582.2","Tissue RNA - fallopian tube [nTPM]":"248.6","Tissue RNA - gallbladder [nTPM]":"231.3","Tissue RNA - heart muscle [nTPM]":"263.9","Tissue RNA - hippocampal formation [nTPM]":"1030.7","Tissue RNA - hypothalamus [nTPM]":"1086.0","Tissue RNA - kidney [nTPM]":"664.3","Tissue RNA - liver [nTPM]":"707.1","Tissue RNA - lung [nTPM]":"269.0","Tissue RNA - lymph node [nTPM]":"273.3","Tissue RNA - medulla oblongata [nTPM]":"1062.6","Tissue RNA - midbrain [nTPM]":"1045.6","Tissue RNA - ovary [nTPM]":"207.4","Tissue RNA - pancreas [nTPM]":"373.0","Tissue RNA - parathyroid gland [nTPM]":"986.0","Tissue RNA - pituitary gland [nTPM]":"344.2","Tissue RNA - placenta [nTPM]":"193.5","Tissue RNA - pons [nTPM]":"1075.6","Tissue RNA - prostate [nTPM]":"282.7","Tissue RNA - rectum [nTPM]":"443.1","Tissue RNA - retina [nTPM]":"392.4","Tissue RNA - salivary gland [nTPM]":"373.3","Tissue RNA - seminal vesicle [nTPM]":"244.3","Tissue RNA - skeletal muscle [nTPM]":"59.7","Tissue RNA - skin 1 [nTPM]":"372.2","Tissue RNA - small intestine [nTPM]":"481.2","Tissue RNA - smooth muscle [nTPM]":"230.4","Tissue RNA - spinal cord [nTPM]":"995.3","Tissue RNA - spleen [nTPM]":"262.3","Tissue RNA - stomach 1 [nTPM]":"493.9","Tissue RNA - testis [nTPM]":"224.4","Tissue RNA - thalamus [nTPM]":"1086.7","Tissue RNA - thymus [nTPM]":"327.9","Tissue RNA - thyroid gland [nTPM]":"316.1","Tissue RNA - tongue [nTPM]":"88.5","Tissue RNA - tonsil [nTPM]":"255.3","Tissue RNA - urinary bladder [nTPM]":"319.6","Tissue RNA - vagina [nTPM]":"348.8","Tissue RNA - white matter [nTPM]":"1046.6","Cell RNA - A-431 [nTPM]":"532.7","Cell RNA - A549 [nTPM]":"1142.5","Cell RNA - AF22 [nTPM]":"627.4","Cell RNA - AN3-CA [nTPM]":"653.5","Cell RNA - ASC diff [nTPM]":"475.4","Cell RNA - ASC TERT1 [nTPM]":"403.9","Cell RNA - BEWO [nTPM]":"755.8","Cell RNA - BJ [nTPM]":"327.1","Cell RNA - BJ hTERT+ [nTPM]":"447.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"585.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"497.2","Cell RNA - CACO-2 [nTPM]":"1388.3","Cell RNA - CAPAN-2 [nTPM]":"528.9","Cell RNA - Daudi [nTPM]":"1115.9","Cell RNA - EFO-21 [nTPM]":"955.5","Cell RNA - fHDF\/TERT166 [nTPM]":"477.1","Cell RNA - GAMG [nTPM]":"442.6","Cell RNA - HaCaT [nTPM]":"865.0","Cell RNA - HAP1 [nTPM]":"624.6","Cell RNA - HBEC3-KT [nTPM]":"737.3","Cell RNA - HBF TERT88 [nTPM]":"382.3","Cell RNA - HDLM-2 [nTPM]":"663.5","Cell RNA - HEK 293 [nTPM]":"1314.3","Cell RNA - HEL [nTPM]":"596.5","Cell RNA - HeLa [nTPM]":"594.9","Cell RNA - Hep G2 [nTPM]":"1036.8","Cell RNA - HHSteC [nTPM]":"434.6","Cell RNA - HL-60 [nTPM]":"661.9","Cell RNA - HMC-1 [nTPM]":"405.9","Cell RNA - HSkMC [nTPM]":"487.3","Cell RNA - hTCEpi [nTPM]":"895.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"531.3","Cell RNA - hTERT-HME1 [nTPM]":"632.3","Cell RNA - hTERT-RPE1 [nTPM]":"477.0","Cell RNA - HUVEC TERT2 [nTPM]":"505.0","Cell RNA - JURKAT [nTPM]":"801.0","Cell RNA - K-562 [nTPM]":"602.9","Cell RNA - Karpas-707 [nTPM]":"337.1","Cell RNA - LHCN-M2 [nTPM]":"494.2","Cell RNA - MCF7 [nTPM]":"1528.7","Cell RNA - MOLT-4 [nTPM]":"965.1","Cell RNA - NB-4 [nTPM]":"1667.1","Cell RNA - NTERA-2 [nTPM]":"566.1","Cell RNA - OE19 [nTPM]":"1034.6","Cell RNA - PC-3 [nTPM]":"1627.5","Cell RNA - REH [nTPM]":"644.7","Cell RNA - RH-30 [nTPM]":"414.7","Cell RNA - RPMI-8226 [nTPM]":"1044.5","Cell RNA - RPTEC TERT1 [nTPM]":"945.3","Cell RNA - RT4 [nTPM]":"1302.6","Cell RNA - SCLC-21H [nTPM]":"822.4","Cell RNA - SH-SY5Y [nTPM]":"708.6","Cell RNA - SiHa [nTPM]":"595.6","Cell RNA - SK-BR-3 [nTPM]":"589.9","Cell RNA - SK-MEL-30 [nTPM]":"803.5","Cell RNA - SuSa [nTPM]":"347.1","Cell RNA - T-47d [nTPM]":"1051.4","Cell RNA - THP-1 [nTPM]":"742.9","Cell RNA - TIME [nTPM]":"373.0","Cell RNA - U-138 MG [nTPM]":"355.0","Cell RNA - U-2 OS [nTPM]":"431.9","Cell RNA - U-2197 [nTPM]":"370.9","Cell RNA - U-251 MG [nTPM]":"466.8","Cell RNA - U-266\/70 [nTPM]":"513.0","Cell RNA - U-266\/84 [nTPM]":"791.3","Cell RNA - U-698 [nTPM]":"897.5","Cell RNA - U-87 MG [nTPM]":"558.7","Cell RNA - U-937 [nTPM]":"643.2","Cell RNA - WM-115 [nTPM]":"484.9","Blood RNA - basophil [nTPM]":"225.6","Blood RNA - classical monocyte [nTPM]":"347.3","Blood RNA - eosinophil [nTPM]":"316.4","Blood RNA - gdT-cell [nTPM]":"258.9","Blood RNA - intermediate monocyte [nTPM]":"353.6","Blood RNA - MAIT T-cell [nTPM]":"278.9","Blood RNA - memory B-cell [nTPM]":"377.1","Blood RNA - memory CD4 T-cell [nTPM]":"305.3","Blood RNA - memory CD8 T-cell [nTPM]":"287.3","Blood RNA - myeloid DC [nTPM]":"486.9","Blood RNA - naive B-cell [nTPM]":"296.9","Blood RNA - naive CD4 T-cell [nTPM]":"279.3","Blood RNA - naive CD8 T-cell [nTPM]":"287.3","Blood RNA - neutrophil [nTPM]":"297.9","Blood RNA - NK-cell [nTPM]":"253.7","Blood RNA - non-classical monocyte [nTPM]":"374.0","Blood RNA - plasmacytoid DC [nTPM]":"516.7","Blood RNA - T-reg [nTPM]":"460.6","Blood RNA - total PBMC [nTPM]":"534.3","Brain RNA - amygdala [nTPM]":"1004.7","Brain RNA - basal ganglia [nTPM]":"1040.0","Brain RNA - cerebellum [nTPM]":"1052.0","Brain RNA - cerebral cortex [nTPM]":"1305.8","Brain RNA - hippocampal formation [nTPM]":"1030.7","Brain RNA - hypothalamus [nTPM]":"1086.0","Brain RNA - medulla oblongata [nTPM]":"1062.6","Brain RNA - midbrain [nTPM]":"1045.6","Brain RNA - pons [nTPM]":"1075.6","Brain RNA - spinal cord [nTPM]":"995.3","Brain RNA - thalamus [nTPM]":"1086.7","Brain RNA - white matter [nTPM]":"1046.6","Single Cell Type RNA - Adipocytes [nTPM]":"346.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"397.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"312.4","Single Cell Type RNA - Astrocytes [nTPM]":"41.1","Single Cell Type RNA - B-cells [nTPM]":"355.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"383.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"526.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1145.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"508.2","Single Cell Type RNA - Bipolar cells [nTPM]":"238.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"411.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"426.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"124.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"543.3","Single Cell Type RNA - Club cells [nTPM]":"683.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"774.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"577.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"774.8","Single Cell Type RNA - dendritic cells [nTPM]":"289.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1306.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1481.1","Single Cell Type RNA - Ductal cells [nTPM]":"659.4","Single Cell Type RNA - Early spermatids [nTPM]":"207.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"487.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"239.6","Single Cell Type RNA - Endothelial cells [nTPM]":"311.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"515.7","Single Cell Type RNA - Erythroid cells [nTPM]":"348.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"661.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"701.5","Single Cell Type RNA - Fibroblasts [nTPM]":"304.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"437.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"425.9","Single Cell Type RNA - granulocytes [nTPM]":"272.2","Single Cell Type RNA - Granulosa cells [nTPM]":"263.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"266.0","Single Cell Type RNA - Hepatocytes [nTPM]":"971.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"779.3","Single Cell Type RNA - Horizontal cells [nTPM]":"146.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"861.7","Single Cell Type RNA - Ionocytes [nTPM]":"980.6","Single Cell Type RNA - Kupffer cells [nTPM]":"376.6","Single Cell Type RNA - Langerhans cells [nTPM]":"426.0","Single Cell Type RNA - Late spermatids [nTPM]":"136.4","Single Cell Type RNA - Leydig cells [nTPM]":"302.0","Single Cell Type RNA - Macrophages [nTPM]":"377.7","Single Cell Type RNA - Melanocytes [nTPM]":"524.7","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"583.9","Single Cell Type RNA - Muller glia cells [nTPM]":"440.8","Single Cell Type RNA - NK-cells [nTPM]":"332.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"56.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"726.1","Single Cell Type RNA - Paneth cells [nTPM]":"1417.1","Single Cell Type RNA - Peritubular cells [nTPM]":"265.5","Single Cell Type RNA - Plasma cells [nTPM]":"565.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"506.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1857.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1701.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"718.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"414.2","Single Cell Type RNA - Sertoli cells [nTPM]":"341.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"259.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"508.6","Single Cell Type RNA - Spermatocytes [nTPM]":"455.8","Single Cell Type RNA - Spermatogonia [nTPM]":"373.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1155.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"388.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"927.2","Single Cell Type RNA - T-cells [nTPM]":"341.0","Single Cell Type RNA - Theca cells [nTPM]":"399.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1049.7","Single Cell Type RNA - Urothelial cells [nTPM]":"778.9"},{"Gene":"CP","Gene synonym":[],"Ensembl":"ENSG00000047457","Gene description":"Ceruloplasmin","Uniprot":["P00450"],"Chromosome":"3","Position":"149162410-149221829","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"liver":"1871.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"558.1","Glandular and luminal cells":"406.0","Hepatocytes":"1687.2","Muller glia cells":"720.5","Respiratory ciliated cells":"318.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"98.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"EFO-21":"318.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001834","CAB008591"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":160000000000,"Blood concentration - Conc. blood MS [pg\/L]":"440000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB008591":"AB_1613734","HPA001834":"AB_1078502"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.0","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"17.9","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"18.1","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"20.8","Tissue RNA - cerebellum [nTPM]":"18.7","Tissue RNA - cerebral cortex [nTPM]":"29.8","Tissue RNA - cervix [nTPM]":"70.2","Tissue RNA - choroid plexus [nTPM]":"129.2","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"9.8","Tissue RNA - endometrium 1 [nTPM]":"14.8","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"8.3","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"39.2","Tissue RNA - hippocampal formation [nTPM]":"17.5","Tissue RNA - hypothalamus [nTPM]":"33.0","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"1871.4","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"18.9","Tissue RNA - medulla oblongata [nTPM]":"28.1","Tissue RNA - midbrain [nTPM]":"20.3","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"28.6","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"24.9","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"16.4","Tissue RNA - retina [nTPM]":"246.5","Tissue RNA - salivary gland [nTPM]":"39.9","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"13.0","Tissue RNA - small intestine [nTPM]":"20.8","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"19.2","Tissue RNA - spleen [nTPM]":"23.1","Tissue RNA - stomach 1 [nTPM]":"3.0","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"20.1","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"16.1","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"20.0","Tissue RNA - urinary bladder [nTPM]":"23.9","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"29.0","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"18.8","Cell RNA - AF22 [nTPM]":"15.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.3","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"318.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"29.4","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"32.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"2.5","Cell RNA - OE19 [nTPM]":"5.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"16.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"1.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"17.9","Brain RNA - basal ganglia [nTPM]":"18.1","Brain RNA - cerebellum [nTPM]":"18.7","Brain RNA - cerebral cortex [nTPM]":"29.8","Brain RNA - hippocampal formation [nTPM]":"17.5","Brain RNA - hypothalamus [nTPM]":"33.0","Brain RNA - medulla oblongata [nTPM]":"28.1","Brain RNA - midbrain [nTPM]":"20.3","Brain RNA - pons [nTPM]":"24.9","Brain RNA - spinal cord [nTPM]":"19.2","Brain RNA - thalamus [nTPM]":"20.1","Brain RNA - white matter [nTPM]":"29.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"76.6","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"10.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"65.8","Single Cell Type RNA - Club cells [nTPM]":"558.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"83.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"190.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"51.0","Single Cell Type RNA - Endothelial cells [nTPM]":"12.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"34.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"16.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"406.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1687.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"44.6","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"4.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"720.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"69.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"318.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"4.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"79.0"},{"Gene":"CPA6","Gene synonym":["CPAH"],"Ensembl":"ENSG00000165078","Gene description":"Carboxypeptidase A6","Uniprot":["Q8N4T0"],"Chromosome":"8","Position":"67422038-67746378","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"2.3","prostate":"2.7","retina":"2.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"31.7","Early spermatids":"21.7","Microglial cells":"12.2","Muller glia cells":"22.5","Pancreatic endocrine cells":"21.5","Paneth cells":"12.8","Prostatic glandular cells":"11.3","Urothelial cells":"36.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"2.5","EFO-21":"1.5","Hep G2":"3.4","OE19":"1.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"olfactory bulb":"12.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"21.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"22.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.5","Single Cell Type RNA - Paneth cells [nTPM]":"12.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.7","Single Cell Type RNA - Urothelial cells [nTPM]":"36.6"},{"Gene":"CPLX1","Gene synonym":["CPX-I"],"Ensembl":"ENSG00000168993","Gene description":"Complexin 1","Uniprot":["O14810"],"Chromosome":"4","Position":"784957-826129","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Exocytosis","Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"273.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"45.5","Bipolar cells":"33.4","Endothelial cells":"29.6","Excitatory neurons":"44.2","Inhibitory neurons":"90.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SCLC-21H":"84.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071191","HPA074390"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA071191":null,"HPA074390":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.20e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.05e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.2","Tissue RNA - adrenal gland [nTPM]":"13.4","Tissue RNA - amygdala [nTPM]":"26.1","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"43.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"18.2","Tissue RNA - cerebellum [nTPM]":"59.7","Tissue RNA - cerebral cortex [nTPM]":"273.5","Tissue RNA - cervix [nTPM]":"16.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"5.0","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"10.8","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"5.7","Tissue RNA - fallopian tube [nTPM]":"16.4","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"18.5","Tissue RNA - hypothalamus [nTPM]":"72.8","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"8.3","Tissue RNA - lung [nTPM]":"9.4","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"135.5","Tissue RNA - midbrain [nTPM]":"25.1","Tissue RNA - ovary [nTPM]":"9.4","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"12.8","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"128.2","Tissue RNA - prostate [nTPM]":"13.8","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"9.6","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"4.1","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"13.9","Tissue RNA - spleen [nTPM]":"27.2","Tissue RNA - stomach 1 [nTPM]":"4.9","Tissue RNA - testis [nTPM]":"8.6","Tissue RNA - thalamus [nTPM]":"124.2","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"7.5","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"8.3","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"89.9","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"4.2","Cell RNA - EFO-21 [nTPM]":"1.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.3","Cell RNA - K-562 [nTPM]":"2.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.5","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"4.4","Cell RNA - PC-3 [nTPM]":"2.6","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"84.3","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"5.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"4.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"26.1","Brain RNA - basal ganglia [nTPM]":"43.0","Brain RNA - cerebellum [nTPM]":"59.7","Brain RNA - cerebral cortex [nTPM]":"273.5","Brain RNA - hippocampal formation [nTPM]":"18.5","Brain RNA - hypothalamus [nTPM]":"72.8","Brain RNA - medulla oblongata [nTPM]":"135.5","Brain RNA - midbrain [nTPM]":"25.1","Brain RNA - pons [nTPM]":"128.2","Brain RNA - spinal cord [nTPM]":"13.9","Brain RNA - thalamus [nTPM]":"124.2","Brain RNA - white matter [nTPM]":"89.9","Single Cell Type RNA - Adipocytes [nTPM]":"45.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"33.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"2.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"29.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"4.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"90.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"16.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"5.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"4.3","Single Cell Type RNA - Spermatogonia [nTPM]":"9.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"CPT1C","Gene synonym":["CATL1","CPT1P","CPTIC","FLJ23809"],"Ensembl":"ENSG00000169169","Gene description":"Carnitine palmitoyltransferase 1C","Uniprot":["Q8TCG5"],"Chromosome":"19","Position":"49690898-49713731","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"19.2","pituitary gland":"28.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"43.4","Excitatory neurons":"34.0","Horizontal cells":"32.0","Inhibitory neurons":"28.1","Late spermatids":"29.7","Oligodendrocyte precursor cells":"21.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"9.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"40.2","AN3-CA":"33.2","SCLC-21H":"27.4","SH-SY5Y":"70.1","U-87 MG":"29.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014529","HPA063621"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA014529":"AB_1847206","HPA063621":"AB_2732706"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.84e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"5.3","Tissue RNA - amygdala [nTPM]":"14.0","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"14.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"19.1","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"18.8","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"4.9","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"19.2","Tissue RNA - hypothalamus [nTPM]":"15.6","Tissue RNA - kidney [nTPM]":"1.7","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"10.1","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"28.4","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"10.3","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"4.6","Tissue RNA - spinal cord [nTPM]":"4.9","Tissue RNA - spleen [nTPM]":"4.9","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"12.9","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"14.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"40.2","Cell RNA - AN3-CA [nTPM]":"33.2","Cell RNA - ASC diff [nTPM]":"14.0","Cell RNA - ASC TERT1 [nTPM]":"11.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"12.6","Cell RNA - BJ hTERT+ [nTPM]":"25.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.4","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.7","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"8.5","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"22.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"12.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.3","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"22.2","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"27.4","Cell RNA - SH-SY5Y [nTPM]":"70.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"18.3","Cell RNA - U-138 MG [nTPM]":"1.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"6.7","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"3.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"29.5","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"14.0","Brain RNA - basal ganglia [nTPM]":"14.8","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"19.1","Brain RNA - hippocampal formation [nTPM]":"19.2","Brain RNA - hypothalamus [nTPM]":"15.6","Brain RNA - medulla oblongata [nTPM]":"10.1","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"10.3","Brain RNA - spinal cord [nTPM]":"4.9","Brain RNA - thalamus [nTPM]":"12.9","Brain RNA - white matter [nTPM]":"14.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"43.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.4","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"29.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"18.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"4.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"CRAT","Gene synonym":["CAT1"],"Ensembl":"ENSG00000095321","Gene description":"Carnitine O-acetyltransferase","Uniprot":["P43155"],"Chromosome":"9","Position":"129094142-129111189","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Transport"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"227.5","tongue":"201.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"181.2","Late spermatids":"521.8","Proximal enterocytes":"136.4","Spermatocytes":"123.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019230","HPA020260","HPA022815"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8100","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA019230":"AB_1847212","HPA020260":"AB_1847210","HPA022815":"AB_2732427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.36e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"36.1","Tissue RNA - adrenal gland [nTPM]":"51.3","Tissue RNA - amygdala [nTPM]":"26.4","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"26.6","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"29.2","Tissue RNA - cerebellum [nTPM]":"27.0","Tissue RNA - cerebral cortex [nTPM]":"33.8","Tissue RNA - cervix [nTPM]":"31.7","Tissue RNA - choroid plexus [nTPM]":"27.5","Tissue RNA - colon [nTPM]":"36.1","Tissue RNA - duodenum [nTPM]":"33.0","Tissue RNA - endometrium 1 [nTPM]":"24.8","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"37.3","Tissue RNA - fallopian tube [nTPM]":"23.1","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"68.2","Tissue RNA - hippocampal formation [nTPM]":"25.1","Tissue RNA - hypothalamus [nTPM]":"27.8","Tissue RNA - kidney [nTPM]":"46.9","Tissue RNA - liver [nTPM]":"151.2","Tissue RNA - lung [nTPM]":"15.2","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"28.8","Tissue RNA - midbrain [nTPM]":"28.2","Tissue RNA - ovary [nTPM]":"23.0","Tissue RNA - pancreas [nTPM]":"107.1","Tissue RNA - parathyroid gland [nTPM]":"26.3","Tissue RNA - pituitary gland [nTPM]":"12.3","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"30.6","Tissue RNA - prostate [nTPM]":"42.2","Tissue RNA - rectum [nTPM]":"4.2","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"32.8","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"227.5","Tissue RNA - skin 1 [nTPM]":"29.6","Tissue RNA - small intestine [nTPM]":"37.2","Tissue RNA - smooth muscle [nTPM]":"6.8","Tissue RNA - spinal cord [nTPM]":"26.7","Tissue RNA - spleen [nTPM]":"15.2","Tissue RNA - stomach 1 [nTPM]":"34.0","Tissue RNA - testis [nTPM]":"146.4","Tissue RNA - thalamus [nTPM]":"30.2","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"21.5","Tissue RNA - tongue [nTPM]":"201.3","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"31.3","Tissue RNA - vagina [nTPM]":"27.5","Tissue RNA - white matter [nTPM]":"24.4","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"39.3","Cell RNA - AF22 [nTPM]":"10.7","Cell RNA - AN3-CA [nTPM]":"21.3","Cell RNA - ASC diff [nTPM]":"13.4","Cell RNA - ASC TERT1 [nTPM]":"25.9","Cell RNA - BEWO [nTPM]":"17.0","Cell RNA - BJ [nTPM]":"15.0","Cell RNA - BJ hTERT+ [nTPM]":"16.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.0","Cell RNA - CACO-2 [nTPM]":"7.8","Cell RNA - CAPAN-2 [nTPM]":"14.0","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"9.2","Cell RNA - fHDF\/TERT166 [nTPM]":"25.9","Cell RNA - GAMG [nTPM]":"23.2","Cell RNA - HaCaT [nTPM]":"6.7","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"4.9","Cell RNA - HBF TERT88 [nTPM]":"7.2","Cell RNA - HDLM-2 [nTPM]":"23.6","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"19.1","Cell RNA - Hep G2 [nTPM]":"30.4","Cell RNA - HHSteC [nTPM]":"34.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"26.1","Cell RNA - HSkMC [nTPM]":"26.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.7","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"15.8","Cell RNA - HUVEC TERT2 [nTPM]":"26.2","Cell RNA - JURKAT [nTPM]":"7.2","Cell RNA - K-562 [nTPM]":"3.6","Cell RNA - Karpas-707 [nTPM]":"5.7","Cell RNA - LHCN-M2 [nTPM]":"20.0","Cell RNA - MCF7 [nTPM]":"9.1","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"15.9","Cell RNA - NTERA-2 [nTPM]":"2.8","Cell RNA - OE19 [nTPM]":"32.0","Cell RNA - PC-3 [nTPM]":"18.0","Cell RNA - REH [nTPM]":"16.8","Cell RNA - RH-30 [nTPM]":"21.8","Cell RNA - RPMI-8226 [nTPM]":"12.2","Cell RNA - RPTEC TERT1 [nTPM]":"18.0","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"4.2","Cell RNA - SH-SY5Y [nTPM]":"12.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"7.1","Cell RNA - SK-MEL-30 [nTPM]":"4.8","Cell RNA - SuSa [nTPM]":"3.4","Cell RNA - T-47d [nTPM]":"49.7","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"22.6","Cell RNA - U-138 MG [nTPM]":"23.0","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"32.1","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"25.5","Cell RNA - U-266\/84 [nTPM]":"22.6","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"28.8","Cell RNA - U-937 [nTPM]":"4.2","Cell RNA - WM-115 [nTPM]":"16.8","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"8.4","Blood RNA - eosinophil [nTPM]":"3.5","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"5.5","Blood RNA - MAIT T-cell [nTPM]":"6.7","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"8.6","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"5.6","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"6.1","Brain RNA - amygdala [nTPM]":"26.4","Brain RNA - basal ganglia [nTPM]":"26.6","Brain RNA - cerebellum [nTPM]":"27.0","Brain RNA - cerebral cortex [nTPM]":"33.8","Brain RNA - hippocampal formation [nTPM]":"25.1","Brain RNA - hypothalamus [nTPM]":"27.8","Brain RNA - medulla oblongata [nTPM]":"28.8","Brain RNA - midbrain [nTPM]":"28.2","Brain RNA - pons [nTPM]":"30.6","Brain RNA - spinal cord [nTPM]":"26.7","Brain RNA - thalamus [nTPM]":"30.2","Brain RNA - white matter [nTPM]":"24.4","Single Cell Type RNA - Adipocytes [nTPM]":"10.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"57.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"45.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"64.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"22.6","Single Cell Type RNA - Early spermatids [nTPM]":"181.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.5","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"55.6","Single Cell Type RNA - Fibroblasts [nTPM]":"19.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.9","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"65.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.9","Single Cell Type RNA - Langerhans cells [nTPM]":"10.5","Single Cell Type RNA - Late spermatids [nTPM]":"521.8","Single Cell Type RNA - Leydig cells [nTPM]":"22.1","Single Cell Type RNA - Macrophages [nTPM]":"12.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"8.3","Single Cell Type RNA - Muller glia cells [nTPM]":"15.5","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.6","Single Cell Type RNA - Paneth cells [nTPM]":"47.6","Single Cell Type RNA - Peritubular cells [nTPM]":"24.5","Single Cell Type RNA - Plasma cells [nTPM]":"9.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"136.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.7","Single Cell Type RNA - Spermatocytes [nTPM]":"123.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"57.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.3","Single Cell Type RNA - T-cells [nTPM]":"7.6","Single Cell Type RNA - Theca cells [nTPM]":"20.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.3","Single Cell Type RNA - Urothelial cells [nTPM]":"13.8"},{"Gene":"CRB1","Gene synonym":["LCA8","RP12"],"Ensembl":"ENSG00000134376","Gene description":"Crumbs cell polarity complex component 1","Uniprot":["P82279"],"Chromosome":"1","Position":"197268204-197478455","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Leber congenital amaurosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"21.3","retina":"74.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"469.5","Cone photoreceptor cells":"164.7","Inhibitory neurons":"130.1","Muller glia cells":"79.7","Oligodendrocyte precursor cells":"280.0","Oligodendrocytes":"105.6","Rod photoreceptor cells":"149.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"glioma":"2.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"28","RNA blood cell specific nTPM":{"basophil":"7.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"28","RNA blood lineage specific nTPM":{"granulocytes":"7.7"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"HeLa":"12.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061250","HPA063127"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA061250":"AB_2684458","HPA063127":"AB_2684944"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"15.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"17.6","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"19.8","Tissue RNA - cerebral cortex [nTPM]":"20.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"15.8","Tissue RNA - hypothalamus [nTPM]":"14.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"18.7","Tissue RNA - midbrain [nTPM]":"18.4","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"17.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"74.7","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"18.9","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"16.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"21.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"12.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"7.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"15.7","Brain RNA - basal ganglia [nTPM]":"17.6","Brain RNA - cerebellum [nTPM]":"19.8","Brain RNA - cerebral cortex [nTPM]":"20.5","Brain RNA - hippocampal formation [nTPM]":"15.8","Brain RNA - hypothalamus [nTPM]":"14.2","Brain RNA - medulla oblongata [nTPM]":"18.7","Brain RNA - midbrain [nTPM]":"18.4","Brain RNA - pons [nTPM]":"17.5","Brain RNA - spinal cord [nTPM]":"18.9","Brain RNA - thalamus [nTPM]":"16.1","Brain RNA - white matter [nTPM]":"21.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"469.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"164.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"130.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"79.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"280.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"105.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"149.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CRX","Gene synonym":["CORD2","CRD","LCA7","OTX3"],"Ensembl":"ENSG00000105392","Gene description":"Cone-rod homeobox","Uniprot":["O43186"],"Chromosome":"19","Position":"47819779-47843330","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Sensory transduction","Transcription","Transcription regulation","Vision"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cone-rod dystrophy","Disease variant","Leber congenital amaurosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"136","RNA tissue specific nTPM":{"retina":"238.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"136.5","Cone photoreceptor cells":"285.7","Rod photoreceptor cells":"501.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036762","HPA036763"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036762":"AB_10673663","HPA036763":"AB_10670922"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"238.5","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"136.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"13.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"285.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"2.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"59.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"501.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"CRY1","Gene synonym":["PHLL1"],"Ensembl":"ENSG00000008405","Gene description":"Cryptochrome circadian regulator 1","Uniprot":["Q16526"],"Chromosome":"12","Position":"106991364-107093549","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Sensory transduction","Transcription","Transcription regulation"],"Molecular function":["Photoreceptor protein","Receptor","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"108.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018762"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm","Nuclear membrane","Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB018762":"AB_2083970"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.3","Tissue RNA - adrenal gland [nTPM]":"12.4","Tissue RNA - amygdala [nTPM]":"8.5","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"9.8","Tissue RNA - bone marrow [nTPM]":"12.4","Tissue RNA - breast [nTPM]":"11.2","Tissue RNA - cerebellum [nTPM]":"16.2","Tissue RNA - cerebral cortex [nTPM]":"10.9","Tissue RNA - cervix [nTPM]":"11.1","Tissue RNA - choroid plexus [nTPM]":"16.7","Tissue RNA - colon [nTPM]":"12.6","Tissue RNA - duodenum [nTPM]":"11.5","Tissue RNA - endometrium 1 [nTPM]":"14.2","Tissue RNA - epididymis [nTPM]":"6.4","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"16.4","Tissue RNA - gallbladder [nTPM]":"16.7","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"8.4","Tissue RNA - hypothalamus [nTPM]":"9.0","Tissue RNA - kidney [nTPM]":"13.7","Tissue RNA - liver [nTPM]":"13.6","Tissue RNA - lung [nTPM]":"19.3","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"10.1","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"13.5","Tissue RNA - parathyroid gland [nTPM]":"8.8","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"11.3","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"21.3","Tissue RNA - salivary gland [nTPM]":"9.0","Tissue RNA - seminal vesicle [nTPM]":"11.5","Tissue RNA - skeletal muscle [nTPM]":"10.9","Tissue RNA - skin 1 [nTPM]":"9.0","Tissue RNA - small intestine [nTPM]":"12.7","Tissue RNA - smooth muscle [nTPM]":"16.8","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"8.7","Tissue RNA - stomach 1 [nTPM]":"16.2","Tissue RNA - testis [nTPM]":"37.3","Tissue RNA - thalamus [nTPM]":"9.9","Tissue RNA - thymus [nTPM]":"19.0","Tissue RNA - thyroid gland [nTPM]":"17.0","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"15.6","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"17.3","Cell RNA - A549 [nTPM]":"16.9","Cell RNA - AF22 [nTPM]":"20.6","Cell RNA - AN3-CA [nTPM]":"23.0","Cell RNA - ASC diff [nTPM]":"14.6","Cell RNA - ASC TERT1 [nTPM]":"9.1","Cell RNA - BEWO [nTPM]":"36.9","Cell RNA - BJ [nTPM]":"17.9","Cell RNA - BJ hTERT+ [nTPM]":"19.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.2","Cell RNA - CACO-2 [nTPM]":"19.9","Cell RNA - CAPAN-2 [nTPM]":"10.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"11.1","Cell RNA - fHDF\/TERT166 [nTPM]":"16.7","Cell RNA - GAMG [nTPM]":"22.7","Cell RNA - HaCaT [nTPM]":"11.6","Cell RNA - HAP1 [nTPM]":"26.8","Cell RNA - HBEC3-KT [nTPM]":"9.3","Cell RNA - HBF TERT88 [nTPM]":"39.6","Cell RNA - HDLM-2 [nTPM]":"17.3","Cell RNA - HEK 293 [nTPM]":"16.6","Cell RNA - HEL [nTPM]":"16.9","Cell RNA - HeLa [nTPM]":"15.3","Cell RNA - Hep G2 [nTPM]":"13.8","Cell RNA - HHSteC [nTPM]":"18.6","Cell RNA - HL-60 [nTPM]":"17.3","Cell RNA - HMC-1 [nTPM]":"14.2","Cell RNA - HSkMC [nTPM]":"8.6","Cell RNA - hTCEpi [nTPM]":"9.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.4","Cell RNA - hTERT-HME1 [nTPM]":"24.9","Cell RNA - hTERT-RPE1 [nTPM]":"17.8","Cell RNA - HUVEC TERT2 [nTPM]":"30.5","Cell RNA - JURKAT [nTPM]":"31.4","Cell RNA - K-562 [nTPM]":"19.3","Cell RNA - Karpas-707 [nTPM]":"14.6","Cell RNA - LHCN-M2 [nTPM]":"22.7","Cell RNA - MCF7 [nTPM]":"12.1","Cell RNA - MOLT-4 [nTPM]":"39.2","Cell RNA - NB-4 [nTPM]":"19.7","Cell RNA - NTERA-2 [nTPM]":"25.1","Cell RNA - OE19 [nTPM]":"16.5","Cell RNA - PC-3 [nTPM]":"24.6","Cell RNA - REH [nTPM]":"34.5","Cell RNA - RH-30 [nTPM]":"52.3","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"25.3","Cell RNA - RT4 [nTPM]":"20.2","Cell RNA - SCLC-21H [nTPM]":"37.1","Cell RNA - SH-SY5Y [nTPM]":"19.2","Cell RNA - SiHa [nTPM]":"33.6","Cell RNA - SK-BR-3 [nTPM]":"22.1","Cell RNA - SK-MEL-30 [nTPM]":"10.9","Cell RNA - SuSa [nTPM]":"20.0","Cell RNA - T-47d [nTPM]":"15.6","Cell RNA - THP-1 [nTPM]":"9.6","Cell RNA - TIME [nTPM]":"13.5","Cell RNA - U-138 MG [nTPM]":"20.9","Cell RNA - U-2 OS [nTPM]":"22.2","Cell RNA - U-2197 [nTPM]":"14.6","Cell RNA - U-251 MG [nTPM]":"16.2","Cell RNA - U-266\/70 [nTPM]":"26.6","Cell RNA - U-266\/84 [nTPM]":"26.6","Cell RNA - U-698 [nTPM]":"7.8","Cell RNA - U-87 MG [nTPM]":"10.2","Cell RNA - U-937 [nTPM]":"16.3","Cell RNA - WM-115 [nTPM]":"17.5","Blood RNA - basophil [nTPM]":"12.0","Blood RNA - classical monocyte [nTPM]":"3.2","Blood RNA - eosinophil [nTPM]":"5.8","Blood RNA - gdT-cell [nTPM]":"12.8","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"16.1","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"9.6","Blood RNA - memory CD8 T-cell [nTPM]":"8.2","Blood RNA - myeloid DC [nTPM]":"4.3","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"8.9","Blood RNA - naive CD8 T-cell [nTPM]":"8.8","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"6.4","Blood RNA - non-classical monocyte [nTPM]":"8.9","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"13.5","Blood RNA - total PBMC [nTPM]":"5.7","Brain RNA - amygdala [nTPM]":"8.5","Brain RNA - basal ganglia [nTPM]":"9.8","Brain RNA - cerebellum [nTPM]":"16.2","Brain RNA - cerebral cortex [nTPM]":"10.9","Brain RNA - hippocampal formation [nTPM]":"8.4","Brain RNA - hypothalamus [nTPM]":"9.0","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"10.1","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"9.9","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"16.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.2","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"9.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"69.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"55.2","Single Cell Type RNA - Bipolar cells [nTPM]":"16.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - dendritic cells [nTPM]":"29.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"11.4","Single Cell Type RNA - Early spermatids [nTPM]":"12.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.3","Single Cell Type RNA - Endothelial cells [nTPM]":"20.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.6","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.4","Single Cell Type RNA - Fibroblasts [nTPM]":"24.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.2","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"6.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.1","Single Cell Type RNA - Hepatocytes [nTPM]":"20.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.3","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"21.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"8.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"16.3","Single Cell Type RNA - Muller glia cells [nTPM]":"22.8","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.5","Single Cell Type RNA - Paneth cells [nTPM]":"7.0","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"15.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.2","Single Cell Type RNA - Spermatocytes [nTPM]":"108.0","Single Cell Type RNA - Spermatogonia [nTPM]":"32.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - T-cells [nTPM]":"29.7","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.8","Single Cell Type RNA - Urothelial cells [nTPM]":"27.0"},{"Gene":"CRYAA","Gene synonym":["CRYA1","HSPB4"],"Ensembl":"ENSG00000160202","Gene description":"Crystallin alpha A","Uniprot":["P02489"],"Chromosome":"21","Position":"43169008-43172805","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Chaperone","Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"kidney":"85.6","retina":"55.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Muller glia cells":"2.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"148","RNA cell line specific nTPM":{"Hep G2":"38.0"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hippocampal formation":"3.9"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037737","HPA038430"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA037737":"AB_2675639","HPA038430":"AB_2732478"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"85.6","Tissue RNA - liver [nTPM]":"6.6","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"55.5","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"38.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CRYAB","Gene synonym":["CRYA2","HSPB5"],"Ensembl":"ENSG00000109846","Gene description":"Crystallin alpha B","Uniprot":["P02511"],"Chromosome":"11","Position":"111908564-111923722","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone","Eye lens protein"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Cataract","Disease variant","Myofibrillar myopathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5623.2","heart muscle":"10683.1","skeletal muscle":"6972.0","tongue":"9406.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"2889.5","Cardiomyocytes":"6878.2","Muller glia cells":"1664.3","Proximal tubular cells":"7285.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"426.4","renal cancer":"575.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"ASC diff":"2663.1","fHDF\/TERT166":"775.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002053","CAB040560","HPA057100"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002053":"AB_442024","CAB040560":null,"HPA057100":"AB_2683337"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.90e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-5"},"Tissue RNA - adipose tissue [nTPM]":"1035.0","Tissue RNA - adrenal gland [nTPM]":"106.6","Tissue RNA - amygdala [nTPM]":"2466.0","Tissue RNA - appendix [nTPM]":"113.9","Tissue RNA - basal ganglia [nTPM]":"3113.8","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"592.2","Tissue RNA - cerebellum [nTPM]":"3032.2","Tissue RNA - cerebral cortex [nTPM]":"5623.2","Tissue RNA - cervix [nTPM]":"439.1","Tissue RNA - choroid plexus [nTPM]":"2077.7","Tissue RNA - colon [nTPM]":"678.9","Tissue RNA - duodenum [nTPM]":"24.6","Tissue RNA - endometrium 1 [nTPM]":"351.4","Tissue RNA - epididymis [nTPM]":"179.1","Tissue RNA - esophagus [nTPM]":"312.2","Tissue RNA - fallopian tube [nTPM]":"204.0","Tissue RNA - gallbladder [nTPM]":"71.7","Tissue RNA - heart muscle [nTPM]":"10683.1","Tissue RNA - hippocampal formation [nTPM]":"2424.9","Tissue RNA - hypothalamus [nTPM]":"2666.2","Tissue RNA - kidney [nTPM]":"2123.2","Tissue RNA - liver [nTPM]":"37.2","Tissue RNA - lung [nTPM]":"253.4","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"3215.2","Tissue RNA - midbrain [nTPM]":"2856.7","Tissue RNA - ovary [nTPM]":"136.0","Tissue RNA - pancreas [nTPM]":"50.6","Tissue RNA - parathyroid gland [nTPM]":"24.9","Tissue RNA - pituitary gland [nTPM]":"209.2","Tissue RNA - placenta [nTPM]":"107.8","Tissue RNA - pons [nTPM]":"3147.1","Tissue RNA - prostate [nTPM]":"317.9","Tissue RNA - rectum [nTPM]":"78.2","Tissue RNA - retina [nTPM]":"478.7","Tissue RNA - salivary gland [nTPM]":"428.7","Tissue RNA - seminal vesicle [nTPM]":"358.5","Tissue RNA - skeletal muscle [nTPM]":"6972.0","Tissue RNA - skin 1 [nTPM]":"317.3","Tissue RNA - small intestine [nTPM]":"158.5","Tissue RNA - smooth muscle [nTPM]":"338.1","Tissue RNA - spinal cord [nTPM]":"2877.3","Tissue RNA - spleen [nTPM]":"88.5","Tissue RNA - stomach 1 [nTPM]":"263.8","Tissue RNA - testis [nTPM]":"23.5","Tissue RNA - thalamus [nTPM]":"2815.5","Tissue RNA - thymus [nTPM]":"20.9","Tissue RNA - thyroid gland [nTPM]":"477.7","Tissue RNA - tongue [nTPM]":"9406.7","Tissue RNA - tonsil [nTPM]":"34.4","Tissue RNA - urinary bladder [nTPM]":"490.0","Tissue RNA - vagina [nTPM]":"477.5","Tissue RNA - white matter [nTPM]":"4060.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"45.0","Cell RNA - ASC diff [nTPM]":"2663.1","Cell RNA - ASC TERT1 [nTPM]":"90.9","Cell RNA - BEWO [nTPM]":"15.0","Cell RNA - BJ [nTPM]":"54.5","Cell RNA - BJ hTERT+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.5","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"41.7","Cell RNA - fHDF\/TERT166 [nTPM]":"775.8","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"2.0","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"2.3","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"11.9","Cell RNA - Hep G2 [nTPM]":"3.9","Cell RNA - HHSteC [nTPM]":"16.9","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"77.1","Cell RNA - hTCEpi [nTPM]":"11.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"6.2","Cell RNA - hTERT-RPE1 [nTPM]":"44.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"4.6","Cell RNA - Karpas-707 [nTPM]":"2.5","Cell RNA - LHCN-M2 [nTPM]":"169.5","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"29.8","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"5.3","Cell RNA - SK-BR-3 [nTPM]":"9.1","Cell RNA - SK-MEL-30 [nTPM]":"39.8","Cell RNA - SuSa [nTPM]":"63.5","Cell RNA - T-47d [nTPM]":"4.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.7","Cell RNA - U-138 MG [nTPM]":"310.1","Cell RNA - U-2 OS [nTPM]":"105.0","Cell RNA - U-2197 [nTPM]":"6.5","Cell RNA - U-251 MG [nTPM]":"4.1","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"7.1","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"39.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2466.0","Brain RNA - basal ganglia [nTPM]":"3113.8","Brain RNA - cerebellum [nTPM]":"3032.2","Brain RNA - cerebral cortex [nTPM]":"5623.2","Brain RNA - hippocampal formation [nTPM]":"2424.9","Brain RNA - hypothalamus [nTPM]":"2666.2","Brain RNA - medulla oblongata [nTPM]":"3215.2","Brain RNA - midbrain [nTPM]":"2856.7","Brain RNA - pons [nTPM]":"3147.1","Brain RNA - spinal cord [nTPM]":"2877.3","Brain RNA - thalamus [nTPM]":"2815.5","Brain RNA - white matter [nTPM]":"4060.6","Single Cell Type RNA - Adipocytes [nTPM]":"38.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"96.0","Single Cell Type RNA - B-cells [nTPM]":"51.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"174.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2889.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"72.8","Single Cell Type RNA - Bipolar cells [nTPM]":"16.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"334.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"696.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6878.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"84.4","Single Cell Type RNA - Club cells [nTPM]":"15.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1338.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"677.0","Single Cell Type RNA - Ductal cells [nTPM]":"320.3","Single Cell Type RNA - Early spermatids [nTPM]":"24.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"345.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"265.3","Single Cell Type RNA - Endothelial cells [nTPM]":"88.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"880.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1008.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"16.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"85.8","Single Cell Type RNA - Late spermatids [nTPM]":"12.6","Single Cell Type RNA - Leydig cells [nTPM]":"228.6","Single Cell Type RNA - Macrophages [nTPM]":"67.7","Single Cell Type RNA - Melanocytes [nTPM]":"483.8","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"3.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1664.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"615.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"187.7","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"855.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7285.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.4","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"799.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1053.3","Single Cell Type RNA - Spermatocytes [nTPM]":"21.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"56.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"155.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.4","Single Cell Type RNA - T-cells [nTPM]":"55.4","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"249.0"},{"Gene":"CRYBA1","Gene synonym":["CRYB1"],"Ensembl":"ENSG00000108255","Gene description":"Crystallin beta A1","Uniprot":["P05813"],"Chromosome":"17","Position":"29246859-29254494","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"2.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1.1","Syncytiotrophoblasts":"2.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"AF22":"3.2","BEWO":"4.1","SuSa":"1.0"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"hippocampal formation":"2.7","hypothalamus":"1.2","thalamus":"1.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022016"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA022016":"AB_2732426"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"3.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"4.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CRYBA2","Gene synonym":[],"Ensembl":"ENSG00000163499","Gene description":"Crystallin beta A2","Uniprot":["P53672"],"Chromosome":"2","Position":"218990189-218993422","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.1","pancreas":"16.6","pituitary gland":"13.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"34","RNA single cell type specific nTPM":{"Enteroendocrine cells":"860.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"pancreatic cancer":"16.0"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"11.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"BEWO":"69.6"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"pons and medulla":"4.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062293"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 17: Intestinal endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062293":"AB_2732680"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.62e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"11.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"16.6","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"2.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"4.5","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"69.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"6.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"10.3","Cell RNA - SH-SY5Y [nTPM]":"2.5","Cell RNA - SiHa [nTPM]":"2.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"11.1","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"860.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"10.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.5","Single Cell Type RNA - Paneth cells [nTPM]":"17.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CRYBA4","Gene synonym":[],"Ensembl":"ENSG00000196431","Gene description":"Crystallin beta A4","Uniprot":["P53673"],"Chromosome":"22","Position":"26621963-26630669","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"1.5","testis":"1.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"3.3","NK-cells":"1.0","Spermatogonia":"3.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"2.0","testis cancer":"2.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HEL":"7.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"cerebral cortex":"4.3","hippocampal formation":"4.0"},"Antibody":["HPA071178"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA071178":"AB_2686354"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"3.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CRYBB1","Gene synonym":[],"Ensembl":"ENSG00000100122","Gene description":"Crystallin beta B1","Uniprot":["P53674"],"Chromosome":"22","Position":"26599278-26618027","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"9.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Hofbauer cells":"82.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"intermediate monocyte":"10.3","non-classical monocyte":"7.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"10.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Karpas-707":"43.3","RPMI-8226":"82.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003448","CAB010058"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"89000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010058":"AB_668166","HPA003448":"AB_2732396"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"9.6","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"2.2","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"5.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.5","Cell RNA - HMC-1 [nTPM]":"12.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"43.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"82.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"4.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"1.8","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"2.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"10.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"7.5","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"2.2","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"82.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CRYBB2","Gene synonym":["CCA2","CRYB2","CRYB2A"],"Ensembl":"ENSG00000244752","Gene description":"Crystallin beta B2","Uniprot":["P43320"],"Chromosome":"22","Position":"25212564-25231870","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"10.6","Breast myoepithelial cells":"12.8","Distal tubular cells":"27.4","Melanocytes":"12.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"2.1"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hippocampal formation":"1.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043749"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA043749":"AB_2678652"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"2.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"2.0","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"2.5","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"2.5","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"2.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"2.6","Brain RNA - cerebellum [nTPM]":"2.0","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"2.5","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"2.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"3.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"9.6","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"CRYBB3","Gene synonym":["CRYB3"],"Ensembl":"ENSG00000100053","Gene description":"Crystallin beta B3","Uniprot":["P26998"],"Chromosome":"22","Position":"25199858-25207359","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"2.6","Distal tubular cells":"1.9","granulocytes":"4.5","Muller glia cells":"4.3","Proximal tubular cells":"10.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"1.4","HEK 293":"1.4","HeLa":"1.8","hTERT-HME1":"1.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055840"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytokinetic bridge","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Microtubules"],"Subcellular additional location":["Cytokinetic bridge","Mitotic spindle"],"Antibody RRID":{"HPA055840":"AB_2682939"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"1.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CRYGB","Gene synonym":["CRYG2"],"Ensembl":"ENSG00000182187","Gene description":"Crystallin gamma B","Uniprot":["P07316"],"Chromosome":"2","Position":"208142573-208146158","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"1.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"ovarian cancer":"1.1","testis cancer":"1.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"hippocampal formation":"3.3","hypothalamus":"2.2","thalamus":"2.0"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043386"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043386":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CRYGC","Gene synonym":["CRYG3"],"Ensembl":"ENSG00000163254","Gene description":"Crystallin gamma C","Uniprot":["P07315"],"Chromosome":"2","Position":"208128137-208129828","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"testis":"1.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Early spermatids":"1.9","Granulosa cells":"3.7","Late spermatids":"3.2","Spermatocytes":"2.1","Spermatogonia":"2.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"0.8","ovarian cancer":"1.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"20","RNA mouse brain regional specific nTPM":{"hippocampal formation":"3.2","hypothalamus":"1.5","thalamus":"1.2"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"14","RNA pig brain regional specific nTPM":{"cerebral cortex":"1.2","hippocampal formation":"1.5"},"Antibody":["HPA043386"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043386":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CRYGD","Gene synonym":["CRYG4"],"Ensembl":"ENSG00000118231","Gene description":"Crystallin gamma D","Uniprot":["P07320"],"Chromosome":"2","Position":"208121607-208124524","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"ovary":"8.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Granulosa cells":"140.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"3.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"20","RNA cell line specific nTPM":{"HEL":"10.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041269","HPA043386"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041269":"AB_2732491","HPA043386":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.5","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"10.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"140.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"34.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CRYGS","Gene synonym":["CRYG8"],"Ensembl":"ENSG00000213139","Gene description":"Crystallin gamma S","Uniprot":["P22914"],"Chromosome":"3","Position":"186538441-186546702","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"5.2","Excitatory neurons":"5.4","Inhibitory neurons":"6.0","Microglial cells":"5.6","Oligodendrocyte precursor cells":"6.0","Oligodendrocytes":"7.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035103","HPA063539"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035103":"AB_10696367","HPA063539":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.72e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.73e-4"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"6.5","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"2.8","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"8.0","Tissue RNA - cerebral cortex [nTPM]":"10.5","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"1.7","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"7.0","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"8.1","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"4.8","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"1.7","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"1.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"1.1","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"1.7","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"1.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.8","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"1.5","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"1.7","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"2.2","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"1.0","Cell RNA - U-266\/70 [nTPM]":"1.7","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"1.8","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.5","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"8.0","Brain RNA - cerebral cortex [nTPM]":"10.5","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"7.0","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CRYM","Gene synonym":["DFNA40"],"Ensembl":"ENSG00000103316","Gene description":"Crystallin mu","Uniprot":["Q14894"],"Chromosome":"16","Position":"21238874-21303083","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"78.7","heart muscle":"175.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"126.0","Ionocytes":"114.0","Muller glia cells":"640.7","Proximal tubular cells":"190.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"14.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"21","RNA blood cell specific nTPM":{"plasmacytoid DC":"82.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"dendritic cells":"82.0"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"RPTEC TERT1":"100.3"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"amygdala":"124.0","basal ganglia":"275.1","cerebral cortex":"124.7","hippocampal formation":"324.3","white matter":"128.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019086","HPA030619"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019086":"AB_1847260","HPA030619":"AB_2673551"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"37.4","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"78.7","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"40.6","Tissue RNA - cerebral cortex [nTPM]":"62.2","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"13.6","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"175.3","Tissue RNA - hippocampal formation [nTPM]":"54.0","Tissue RNA - hypothalamus [nTPM]":"31.6","Tissue RNA - kidney [nTPM]":"64.4","Tissue RNA - liver [nTPM]":"14.2","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"13.9","Tissue RNA - midbrain [nTPM]":"19.8","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"8.9","Tissue RNA - pituitary gland [nTPM]":"55.6","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"15.6","Tissue RNA - prostate [nTPM]":"35.4","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"54.7","Tissue RNA - salivary gland [nTPM]":"20.6","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"14.1","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"20.5","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"21.8","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"31.3","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"4.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.8","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"5.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"23.2","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"2.2","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"9.7","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"100.3","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"5.2","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"2.6","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"6.8","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"16.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"82.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"37.4","Brain RNA - basal ganglia [nTPM]":"78.7","Brain RNA - cerebellum [nTPM]":"40.6","Brain RNA - cerebral cortex [nTPM]":"62.2","Brain RNA - hippocampal formation [nTPM]":"54.0","Brain RNA - hypothalamus [nTPM]":"31.6","Brain RNA - medulla oblongata [nTPM]":"13.9","Brain RNA - midbrain [nTPM]":"19.8","Brain RNA - pons [nTPM]":"15.6","Brain RNA - spinal cord [nTPM]":"14.1","Brain RNA - thalamus [nTPM]":"20.5","Brain RNA - white matter [nTPM]":"31.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"126.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"56.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"11.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"19.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"7.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"8.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.6","Single Cell Type RNA - Ionocytes [nTPM]":"114.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"12.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"640.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"2.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"190.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"7.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.2","Single Cell Type RNA - Urothelial cells [nTPM]":"68.0"},{"Gene":"CSF1R","Gene synonym":["C-FMS","CD115","CSFR","FMS"],"Ensembl":"ENSG00000182578","Gene description":"Colony stimulating factor 1 receptor","Uniprot":["P07333"],"Chromosome":"5","Position":"150053291-150113372","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Neurodegeneration","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"113.3","placenta":"103.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"103.2","Hofbauer cells":"340.4","Kupffer cells":"291.2","Langerhans cells":"73.4","Macrophages":"196.3","Microglial cells":"134.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"444.6","non-classical monocyte":"646.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"646.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"BEWO":"123.0","SK-BR-3":"47.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008970","HPA012323"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB008970":null,"HPA012323":"AB_1848977"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.92e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"51.3","Tissue RNA - adrenal gland [nTPM]":"31.0","Tissue RNA - amygdala [nTPM]":"19.6","Tissue RNA - appendix [nTPM]":"75.1","Tissue RNA - basal ganglia [nTPM]":"17.1","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"19.3","Tissue RNA - cerebellum [nTPM]":"20.2","Tissue RNA - cerebral cortex [nTPM]":"21.4","Tissue RNA - cervix [nTPM]":"21.6","Tissue RNA - choroid plexus [nTPM]":"19.3","Tissue RNA - colon [nTPM]":"21.9","Tissue RNA - duodenum [nTPM]":"24.3","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"5.8","Tissue RNA - esophagus [nTPM]":"21.0","Tissue RNA - fallopian tube [nTPM]":"17.2","Tissue RNA - gallbladder [nTPM]":"40.6","Tissue RNA - heart muscle [nTPM]":"16.6","Tissue RNA - hippocampal formation [nTPM]":"19.8","Tissue RNA - hypothalamus [nTPM]":"33.8","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"27.5","Tissue RNA - lung [nTPM]":"36.6","Tissue RNA - lymph node [nTPM]":"54.4","Tissue RNA - medulla oblongata [nTPM]":"41.4","Tissue RNA - midbrain [nTPM]":"35.5","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"11.8","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"103.3","Tissue RNA - pons [nTPM]":"40.1","Tissue RNA - prostate [nTPM]":"9.1","Tissue RNA - rectum [nTPM]":"21.5","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"10.1","Tissue RNA - seminal vesicle [nTPM]":"20.8","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"37.3","Tissue RNA - smooth muscle [nTPM]":"41.9","Tissue RNA - spinal cord [nTPM]":"36.6","Tissue RNA - spleen [nTPM]":"113.3","Tissue RNA - stomach 1 [nTPM]":"21.0","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"40.6","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"21.7","Tissue RNA - urinary bladder [nTPM]":"42.6","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"67.6","Cell RNA - A-431 [nTPM]":"4.5","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.9","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"123.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"5.9","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"6.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"47.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"20.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"3.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"138.4","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"444.6","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"139.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"21.6","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"646.9","Blood RNA - plasmacytoid DC [nTPM]":"11.1","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"132.7","Brain RNA - amygdala [nTPM]":"19.6","Brain RNA - basal ganglia [nTPM]":"17.1","Brain RNA - cerebellum [nTPM]":"20.2","Brain RNA - cerebral cortex [nTPM]":"21.4","Brain RNA - hippocampal formation [nTPM]":"19.8","Brain RNA - hypothalamus [nTPM]":"33.8","Brain RNA - medulla oblongata [nTPM]":"41.4","Brain RNA - midbrain [nTPM]":"35.5","Brain RNA - pons [nTPM]":"40.1","Brain RNA - spinal cord [nTPM]":"36.6","Brain RNA - thalamus [nTPM]":"40.6","Brain RNA - white matter [nTPM]":"67.6","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"103.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"340.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"291.2","Single Cell Type RNA - Langerhans cells [nTPM]":"73.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"196.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"134.9","Single Cell Type RNA - monocytes [nTPM]":"39.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.4","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"2.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CSNK1D","Gene synonym":["CKID","CKIdelta","HCKID"],"Ensembl":"ENSG00000141551","Gene description":"Casein kinase 1 delta","Uniprot":["P48730"],"Chromosome":"17","Position":"82239023-82273731","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Wnt signaling pathway"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"312.5","Late spermatids":"775.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015410"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB015410":"AB_831049"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.38e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.62e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"46.7","Tissue RNA - adrenal gland [nTPM]":"57.0","Tissue RNA - amygdala [nTPM]":"36.9","Tissue RNA - appendix [nTPM]":"28.9","Tissue RNA - basal ganglia [nTPM]":"36.9","Tissue RNA - bone marrow [nTPM]":"25.9","Tissue RNA - breast [nTPM]":"42.3","Tissue RNA - cerebellum [nTPM]":"34.4","Tissue RNA - cerebral cortex [nTPM]":"37.9","Tissue RNA - cervix [nTPM]":"45.3","Tissue RNA - choroid plexus [nTPM]":"30.3","Tissue RNA - colon [nTPM]":"57.1","Tissue RNA - duodenum [nTPM]":"35.1","Tissue RNA - endometrium 1 [nTPM]":"56.6","Tissue RNA - epididymis [nTPM]":"26.7","Tissue RNA - esophagus [nTPM]":"50.8","Tissue RNA - fallopian tube [nTPM]":"45.3","Tissue RNA - gallbladder [nTPM]":"24.8","Tissue RNA - heart muscle [nTPM]":"42.4","Tissue RNA - hippocampal formation [nTPM]":"39.0","Tissue RNA - hypothalamus [nTPM]":"40.2","Tissue RNA - kidney [nTPM]":"45.5","Tissue RNA - liver [nTPM]":"40.9","Tissue RNA - lung [nTPM]":"45.3","Tissue RNA - lymph node [nTPM]":"30.8","Tissue RNA - medulla oblongata [nTPM]":"37.2","Tissue RNA - midbrain [nTPM]":"37.6","Tissue RNA - ovary [nTPM]":"43.1","Tissue RNA - pancreas [nTPM]":"47.5","Tissue RNA - parathyroid gland [nTPM]":"43.1","Tissue RNA - pituitary gland [nTPM]":"54.2","Tissue RNA - placenta [nTPM]":"30.2","Tissue RNA - pons [nTPM]":"36.3","Tissue RNA - prostate [nTPM]":"51.8","Tissue RNA - rectum [nTPM]":"20.0","Tissue RNA - retina [nTPM]":"15.1","Tissue RNA - salivary gland [nTPM]":"48.6","Tissue RNA - seminal vesicle [nTPM]":"36.8","Tissue RNA - skeletal muscle [nTPM]":"88.9","Tissue RNA - skin 1 [nTPM]":"36.4","Tissue RNA - small intestine [nTPM]":"50.9","Tissue RNA - smooth muscle [nTPM]":"29.0","Tissue RNA - spinal cord [nTPM]":"36.3","Tissue RNA - spleen [nTPM]":"56.3","Tissue RNA - stomach 1 [nTPM]":"49.3","Tissue RNA - testis [nTPM]":"60.7","Tissue RNA - thalamus [nTPM]":"42.6","Tissue RNA - thymus [nTPM]":"34.0","Tissue RNA - thyroid gland [nTPM]":"44.7","Tissue RNA - tongue [nTPM]":"38.7","Tissue RNA - tonsil [nTPM]":"22.8","Tissue RNA - urinary bladder [nTPM]":"49.0","Tissue RNA - vagina [nTPM]":"37.0","Tissue RNA - white matter [nTPM]":"32.9","Cell RNA - A-431 [nTPM]":"60.3","Cell RNA - A549 [nTPM]":"70.9","Cell RNA - AF22 [nTPM]":"39.5","Cell RNA - AN3-CA [nTPM]":"54.7","Cell RNA - ASC diff [nTPM]":"50.8","Cell RNA - ASC TERT1 [nTPM]":"53.9","Cell RNA - BEWO [nTPM]":"77.7","Cell RNA - BJ [nTPM]":"85.1","Cell RNA - BJ hTERT+ [nTPM]":"54.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"61.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.8","Cell RNA - CACO-2 [nTPM]":"58.6","Cell RNA - CAPAN-2 [nTPM]":"49.4","Cell RNA - Daudi [nTPM]":"55.0","Cell RNA - EFO-21 [nTPM]":"66.3","Cell RNA - fHDF\/TERT166 [nTPM]":"62.5","Cell RNA - GAMG [nTPM]":"64.8","Cell RNA - HaCaT [nTPM]":"57.1","Cell RNA - HAP1 [nTPM]":"37.4","Cell RNA - HBEC3-KT [nTPM]":"88.3","Cell RNA - HBF TERT88 [nTPM]":"48.9","Cell RNA - HDLM-2 [nTPM]":"47.0","Cell RNA - HEK 293 [nTPM]":"90.5","Cell RNA - HEL [nTPM]":"68.5","Cell RNA - HeLa [nTPM]":"53.4","Cell RNA - Hep G2 [nTPM]":"63.7","Cell RNA - HHSteC [nTPM]":"146.9","Cell RNA - HL-60 [nTPM]":"56.9","Cell RNA - HMC-1 [nTPM]":"50.4","Cell RNA - HSkMC [nTPM]":"81.9","Cell RNA - hTCEpi [nTPM]":"61.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.6","Cell RNA - hTERT-HME1 [nTPM]":"61.3","Cell RNA - hTERT-RPE1 [nTPM]":"76.0","Cell RNA - HUVEC TERT2 [nTPM]":"90.0","Cell RNA - JURKAT [nTPM]":"39.5","Cell RNA - K-562 [nTPM]":"78.5","Cell RNA - Karpas-707 [nTPM]":"28.4","Cell RNA - LHCN-M2 [nTPM]":"58.5","Cell RNA - MCF7 [nTPM]":"70.6","Cell RNA - MOLT-4 [nTPM]":"73.7","Cell RNA - NB-4 [nTPM]":"59.3","Cell RNA - NTERA-2 [nTPM]":"42.2","Cell RNA - OE19 [nTPM]":"71.3","Cell RNA - PC-3 [nTPM]":"108.6","Cell RNA - REH [nTPM]":"62.6","Cell RNA - RH-30 [nTPM]":"48.7","Cell RNA - RPMI-8226 [nTPM]":"49.7","Cell RNA - RPTEC TERT1 [nTPM]":"64.8","Cell RNA - RT4 [nTPM]":"93.4","Cell RNA - SCLC-21H [nTPM]":"48.5","Cell RNA - SH-SY5Y [nTPM]":"87.4","Cell RNA - SiHa [nTPM]":"100.4","Cell RNA - SK-BR-3 [nTPM]":"85.5","Cell RNA - SK-MEL-30 [nTPM]":"97.7","Cell RNA - SuSa [nTPM]":"54.3","Cell RNA - T-47d [nTPM]":"61.5","Cell RNA - THP-1 [nTPM]":"73.0","Cell RNA - TIME [nTPM]":"95.6","Cell RNA - U-138 MG [nTPM]":"86.9","Cell RNA - U-2 OS [nTPM]":"77.3","Cell RNA - U-2197 [nTPM]":"76.2","Cell RNA - U-251 MG [nTPM]":"67.0","Cell RNA - U-266\/70 [nTPM]":"61.0","Cell RNA - U-266\/84 [nTPM]":"32.1","Cell RNA - U-698 [nTPM]":"58.4","Cell RNA - U-87 MG [nTPM]":"69.5","Cell RNA - U-937 [nTPM]":"48.1","Cell RNA - WM-115 [nTPM]":"64.7","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"20.8","Blood RNA - eosinophil [nTPM]":"27.4","Blood RNA - gdT-cell [nTPM]":"12.3","Blood RNA - intermediate monocyte [nTPM]":"21.3","Blood RNA - MAIT T-cell [nTPM]":"11.8","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"9.6","Blood RNA - memory CD8 T-cell [nTPM]":"12.1","Blood RNA - myeloid DC [nTPM]":"20.1","Blood RNA - naive B-cell [nTPM]":"9.0","Blood RNA - naive CD4 T-cell [nTPM]":"8.1","Blood RNA - naive CD8 T-cell [nTPM]":"8.7","Blood RNA - neutrophil [nTPM]":"50.4","Blood RNA - NK-cell [nTPM]":"15.3","Blood RNA - non-classical monocyte [nTPM]":"20.3","Blood RNA - plasmacytoid DC [nTPM]":"9.6","Blood RNA - T-reg [nTPM]":"9.2","Blood RNA - total PBMC [nTPM]":"15.4","Brain RNA - amygdala [nTPM]":"36.9","Brain RNA - basal ganglia [nTPM]":"36.9","Brain RNA - cerebellum [nTPM]":"34.4","Brain RNA - cerebral cortex [nTPM]":"37.9","Brain RNA - hippocampal formation [nTPM]":"39.0","Brain RNA - hypothalamus [nTPM]":"40.2","Brain RNA - medulla oblongata [nTPM]":"37.2","Brain RNA - midbrain [nTPM]":"37.6","Brain RNA - pons [nTPM]":"36.3","Brain RNA - spinal cord [nTPM]":"36.3","Brain RNA - thalamus [nTPM]":"42.6","Brain RNA - white matter [nTPM]":"32.9","Single Cell Type RNA - Adipocytes [nTPM]":"65.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.3","Single Cell Type RNA - Astrocytes [nTPM]":"36.6","Single Cell Type RNA - B-cells [nTPM]":"81.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"116.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"58.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.9","Single Cell Type RNA - Bipolar cells [nTPM]":"46.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"51.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"65.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"61.8","Single Cell Type RNA - dendritic cells [nTPM]":"101.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"105.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"71.6","Single Cell Type RNA - Early spermatids [nTPM]":"312.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"69.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.0","Single Cell Type RNA - Endothelial cells [nTPM]":"54.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.2","Single Cell Type RNA - Erythroid cells [nTPM]":"32.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"69.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"95.2","Single Cell Type RNA - Fibroblasts [nTPM]":"42.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"87.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"93.2","Single Cell Type RNA - granulocytes [nTPM]":"60.1","Single Cell Type RNA - Granulosa cells [nTPM]":"45.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.5","Single Cell Type RNA - Hepatocytes [nTPM]":"33.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"65.3","Single Cell Type RNA - Horizontal cells [nTPM]":"95.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"62.8","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"51.5","Single Cell Type RNA - Langerhans cells [nTPM]":"83.8","Single Cell Type RNA - Late spermatids [nTPM]":"775.6","Single Cell Type RNA - Leydig cells [nTPM]":"30.1","Single Cell Type RNA - Macrophages [nTPM]":"75.7","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"65.8","Single Cell Type RNA - Muller glia cells [nTPM]":"28.7","Single Cell Type RNA - NK-cells [nTPM]":"79.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"87.7","Single Cell Type RNA - Paneth cells [nTPM]":"83.2","Single Cell Type RNA - Peritubular cells [nTPM]":"40.3","Single Cell Type RNA - Plasma cells [nTPM]":"80.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"90.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"94.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"43.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"66.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"54.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"78.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"57.5","Single Cell Type RNA - Spermatocytes [nTPM]":"55.1","Single Cell Type RNA - Spermatogonia [nTPM]":"29.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"44.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"48.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"126.6","Single Cell Type RNA - T-cells [nTPM]":"87.6","Single Cell Type RNA - Theca cells [nTPM]":"46.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"56.7","Single Cell Type RNA - Urothelial cells [nTPM]":"118.6"},{"Gene":"CST3","Gene synonym":[],"Ensembl":"ENSG00000101439","Gene description":"Cystatin C","Uniprot":["P01034"],"Chromosome":"20","Position":"23626706-23638473","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Protease inhibitor","Thiol protease inhibitor"],"Disease involvement":["Age-related macular degeneration","Amyloidosis","Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4217.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"18746.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"classical monocyte":"4967.5","intermediate monocyte":"6424.5","myeloid DC":"7959.0","non-classical monocyte":"4297.7","plasmacytoid DC":"4427.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"7959.0","monocytes":"6424.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1733.4","ASC TERT1":"1179.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000118","HPA013143"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1040000000,"Blood concentration - Conc. blood MS [pg\/L]":"2800000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB000118":null,"HPA013143":"AB_1847417"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.77e-4"},"Tissue RNA - adipose tissue [nTPM]":"1046.2","Tissue RNA - adrenal gland [nTPM]":"707.6","Tissue RNA - amygdala [nTPM]":"3041.2","Tissue RNA - appendix [nTPM]":"262.3","Tissue RNA - basal ganglia [nTPM]":"3117.9","Tissue RNA - bone marrow [nTPM]":"170.8","Tissue RNA - breast [nTPM]":"900.3","Tissue RNA - cerebellum [nTPM]":"2823.3","Tissue RNA - cerebral cortex [nTPM]":"4217.6","Tissue RNA - cervix [nTPM]":"587.8","Tissue RNA - choroid plexus [nTPM]":"3094.8","Tissue RNA - colon [nTPM]":"788.7","Tissue RNA - duodenum [nTPM]":"389.6","Tissue RNA - endometrium 1 [nTPM]":"708.3","Tissue RNA - epididymis [nTPM]":"875.9","Tissue RNA - esophagus [nTPM]":"557.1","Tissue RNA - fallopian tube [nTPM]":"802.7","Tissue RNA - gallbladder [nTPM]":"583.0","Tissue RNA - heart muscle [nTPM]":"1275.3","Tissue RNA - hippocampal formation [nTPM]":"2976.3","Tissue RNA - hypothalamus [nTPM]":"2707.6","Tissue RNA - kidney [nTPM]":"517.4","Tissue RNA - liver [nTPM]":"833.6","Tissue RNA - lung [nTPM]":"595.8","Tissue RNA - lymph node [nTPM]":"463.5","Tissue RNA - medulla oblongata [nTPM]":"3258.4","Tissue RNA - midbrain [nTPM]":"3096.2","Tissue RNA - ovary [nTPM]":"575.8","Tissue RNA - pancreas [nTPM]":"944.1","Tissue RNA - parathyroid gland [nTPM]":"320.0","Tissue RNA - pituitary gland [nTPM]":"670.1","Tissue RNA - placenta [nTPM]":"165.9","Tissue RNA - pons [nTPM]":"2939.3","Tissue RNA - prostate [nTPM]":"773.9","Tissue RNA - rectum [nTPM]":"416.9","Tissue RNA - retina [nTPM]":"46.9","Tissue RNA - salivary gland [nTPM]":"2008.0","Tissue RNA - seminal vesicle [nTPM]":"441.5","Tissue RNA - skeletal muscle [nTPM]":"749.0","Tissue RNA - skin 1 [nTPM]":"497.1","Tissue RNA - small intestine [nTPM]":"800.3","Tissue RNA - smooth muscle [nTPM]":"367.6","Tissue RNA - spinal cord [nTPM]":"3028.1","Tissue RNA - spleen [nTPM]":"723.7","Tissue RNA - stomach 1 [nTPM]":"979.9","Tissue RNA - testis [nTPM]":"761.3","Tissue RNA - thalamus [nTPM]":"3302.7","Tissue RNA - thymus [nTPM]":"418.9","Tissue RNA - thyroid gland [nTPM]":"658.8","Tissue RNA - tongue [nTPM]":"517.4","Tissue RNA - tonsil [nTPM]":"208.1","Tissue RNA - urinary bladder [nTPM]":"703.0","Tissue RNA - vagina [nTPM]":"618.4","Tissue RNA - white matter [nTPM]":"2883.1","Cell RNA - A-431 [nTPM]":"155.2","Cell RNA - A549 [nTPM]":"328.2","Cell RNA - AF22 [nTPM]":"75.4","Cell RNA - AN3-CA [nTPM]":"175.8","Cell RNA - ASC diff [nTPM]":"1733.4","Cell RNA - ASC TERT1 [nTPM]":"1179.8","Cell RNA - BEWO [nTPM]":"145.3","Cell RNA - BJ [nTPM]":"261.4","Cell RNA - BJ hTERT+ [nTPM]":"350.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"170.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"137.7","Cell RNA - CACO-2 [nTPM]":"625.1","Cell RNA - CAPAN-2 [nTPM]":"219.7","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"241.0","Cell RNA - fHDF\/TERT166 [nTPM]":"345.2","Cell RNA - GAMG [nTPM]":"221.3","Cell RNA - HaCaT [nTPM]":"496.2","Cell RNA - HAP1 [nTPM]":"69.6","Cell RNA - HBEC3-KT [nTPM]":"499.9","Cell RNA - HBF TERT88 [nTPM]":"51.9","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"253.5","Cell RNA - HEL [nTPM]":"157.6","Cell RNA - HeLa [nTPM]":"61.1","Cell RNA - Hep G2 [nTPM]":"1082.9","Cell RNA - HHSteC [nTPM]":"621.2","Cell RNA - HL-60 [nTPM]":"7.5","Cell RNA - HMC-1 [nTPM]":"251.0","Cell RNA - HSkMC [nTPM]":"919.0","Cell RNA - hTCEpi [nTPM]":"415.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"226.6","Cell RNA - hTERT-HME1 [nTPM]":"241.5","Cell RNA - hTERT-RPE1 [nTPM]":"352.5","Cell RNA - HUVEC TERT2 [nTPM]":"268.5","Cell RNA - JURKAT [nTPM]":"18.5","Cell RNA - K-562 [nTPM]":"147.6","Cell RNA - Karpas-707 [nTPM]":"4.0","Cell RNA - LHCN-M2 [nTPM]":"239.5","Cell RNA - MCF7 [nTPM]":"234.4","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"162.2","Cell RNA - NTERA-2 [nTPM]":"103.5","Cell RNA - OE19 [nTPM]":"461.9","Cell RNA - PC-3 [nTPM]":"752.2","Cell RNA - REH [nTPM]":"5.7","Cell RNA - RH-30 [nTPM]":"96.4","Cell RNA - RPMI-8226 [nTPM]":"215.2","Cell RNA - RPTEC TERT1 [nTPM]":"708.0","Cell RNA - RT4 [nTPM]":"328.3","Cell RNA - SCLC-21H [nTPM]":"84.7","Cell RNA - SH-SY5Y [nTPM]":"98.2","Cell RNA - SiHa [nTPM]":"191.1","Cell RNA - SK-BR-3 [nTPM]":"54.6","Cell RNA - SK-MEL-30 [nTPM]":"343.3","Cell RNA - SuSa [nTPM]":"107.7","Cell RNA - T-47d [nTPM]":"156.5","Cell RNA - THP-1 [nTPM]":"548.2","Cell RNA - TIME [nTPM]":"702.0","Cell RNA - U-138 MG [nTPM]":"163.4","Cell RNA - U-2 OS [nTPM]":"119.0","Cell RNA - U-2197 [nTPM]":"231.6","Cell RNA - U-251 MG [nTPM]":"97.7","Cell RNA - U-266\/70 [nTPM]":"157.1","Cell RNA - U-266\/84 [nTPM]":"6.2","Cell RNA - U-698 [nTPM]":"1.8","Cell RNA - U-87 MG [nTPM]":"138.0","Cell RNA - U-937 [nTPM]":"339.5","Cell RNA - WM-115 [nTPM]":"184.0","Blood RNA - basophil [nTPM]":"48.1","Blood RNA - classical monocyte [nTPM]":"4967.5","Blood RNA - eosinophil [nTPM]":"33.2","Blood RNA - gdT-cell [nTPM]":"66.9","Blood RNA - intermediate monocyte [nTPM]":"6424.5","Blood RNA - MAIT T-cell [nTPM]":"25.5","Blood RNA - memory B-cell [nTPM]":"23.1","Blood RNA - memory CD4 T-cell [nTPM]":"18.3","Blood RNA - memory CD8 T-cell [nTPM]":"45.8","Blood RNA - myeloid DC [nTPM]":"7959.0","Blood RNA - naive B-cell [nTPM]":"13.6","Blood RNA - naive CD4 T-cell [nTPM]":"16.9","Blood RNA - naive CD8 T-cell [nTPM]":"31.1","Blood RNA - neutrophil [nTPM]":"809.3","Blood RNA - NK-cell [nTPM]":"191.4","Blood RNA - non-classical monocyte [nTPM]":"4297.7","Blood RNA - plasmacytoid DC [nTPM]":"4427.4","Blood RNA - T-reg [nTPM]":"13.6","Blood RNA - total PBMC [nTPM]":"4250.8","Brain RNA - amygdala [nTPM]":"3041.2","Brain RNA - basal ganglia [nTPM]":"3117.9","Brain RNA - cerebellum [nTPM]":"2823.3","Brain RNA - cerebral cortex [nTPM]":"4217.6","Brain RNA - hippocampal formation [nTPM]":"2976.3","Brain RNA - hypothalamus [nTPM]":"2707.6","Brain RNA - medulla oblongata [nTPM]":"3258.4","Brain RNA - midbrain [nTPM]":"3096.2","Brain RNA - pons [nTPM]":"2939.3","Brain RNA - spinal cord [nTPM]":"3028.1","Brain RNA - thalamus [nTPM]":"3302.7","Brain RNA - white matter [nTPM]":"2883.1","Single Cell Type RNA - Adipocytes [nTPM]":"662.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"115.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"168.8","Single Cell Type RNA - Astrocytes [nTPM]":"849.5","Single Cell Type RNA - B-cells [nTPM]":"93.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"942.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"571.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"568.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"213.9","Single Cell Type RNA - Bipolar cells [nTPM]":"152.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"660.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"512.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"240.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1361.2","Single Cell Type RNA - Club cells [nTPM]":"514.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"641.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"476.8","Single Cell Type RNA - dendritic cells [nTPM]":"603.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1889.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"414.8","Single Cell Type RNA - Ductal cells [nTPM]":"489.9","Single Cell Type RNA - Early spermatids [nTPM]":"46.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"441.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"795.0","Single Cell Type RNA - Endothelial cells [nTPM]":"728.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"882.1","Single Cell Type RNA - Erythroid cells [nTPM]":"252.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"783.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"308.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3026.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"981.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"631.0","Single Cell Type RNA - granulocytes [nTPM]":"359.9","Single Cell Type RNA - Granulosa cells [nTPM]":"687.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"491.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2563.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1816.7","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1360.6","Single Cell Type RNA - Ionocytes [nTPM]":"691.7","Single Cell Type RNA - Kupffer cells [nTPM]":"4301.1","Single Cell Type RNA - Langerhans cells [nTPM]":"18746.6","Single Cell Type RNA - Late spermatids [nTPM]":"184.3","Single Cell Type RNA - Leydig cells [nTPM]":"2132.6","Single Cell Type RNA - Macrophages [nTPM]":"4542.6","Single Cell Type RNA - Melanocytes [nTPM]":"1563.5","Single Cell Type RNA - Microglial cells [nTPM]":"87.1","Single Cell Type RNA - monocytes [nTPM]":"2025.6","Single Cell Type RNA - Muller glia cells [nTPM]":"248.7","Single Cell Type RNA - NK-cells [nTPM]":"99.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"263.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1458.5","Single Cell Type RNA - Paneth cells [nTPM]":"2342.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1790.4","Single Cell Type RNA - Plasma cells [nTPM]":"67.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"786.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4301.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1098.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"364.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.3","Single Cell Type RNA - Sertoli cells [nTPM]":"2195.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1417.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"846.2","Single Cell Type RNA - Spermatocytes [nTPM]":"125.5","Single Cell Type RNA - Spermatogonia [nTPM]":"400.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"461.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"822.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"469.0","Single Cell Type RNA - T-cells [nTPM]":"117.4","Single Cell Type RNA - Theca cells [nTPM]":"208.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1039.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1079.7"},{"Gene":"CSTB","Gene synonym":["CST6","EPM1","PME","STFB"],"Ensembl":"ENSG00000160213","Gene description":"Cystatin B","Uniprot":["P04080"],"Chromosome":"21","Position":"43772511-43776330","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Protease inhibitor","Thiol protease inhibitor"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"esophagus":"11304.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"5910.7","Club cells":"4352.8","Hofbauer cells":"2827.7","Squamous epithelial cells":"4910.2","Urothelial cells":"3198.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RT4":"2798.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017380","CAB047320","HPA058557"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8700000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB047320":null,"HPA017380":"AB_1847414","HPA058557":"AB_2683755"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.66e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"224.3","Tissue RNA - adrenal gland [nTPM]":"165.6","Tissue RNA - amygdala [nTPM]":"254.1","Tissue RNA - appendix [nTPM]":"141.6","Tissue RNA - basal ganglia [nTPM]":"253.6","Tissue RNA - bone marrow [nTPM]":"73.8","Tissue RNA - breast [nTPM]":"161.9","Tissue RNA - cerebellum [nTPM]":"255.4","Tissue RNA - cerebral cortex [nTPM]":"314.6","Tissue RNA - cervix [nTPM]":"585.8","Tissue RNA - choroid plexus [nTPM]":"275.2","Tissue RNA - colon [nTPM]":"243.8","Tissue RNA - duodenum [nTPM]":"122.9","Tissue RNA - endometrium 1 [nTPM]":"90.1","Tissue RNA - epididymis [nTPM]":"175.0","Tissue RNA - esophagus [nTPM]":"11304.7","Tissue RNA - fallopian tube [nTPM]":"154.1","Tissue RNA - gallbladder [nTPM]":"150.7","Tissue RNA - heart muscle [nTPM]":"192.2","Tissue RNA - hippocampal formation [nTPM]":"252.8","Tissue RNA - hypothalamus [nTPM]":"263.0","Tissue RNA - kidney [nTPM]":"144.7","Tissue RNA - liver [nTPM]":"189.4","Tissue RNA - lung [nTPM]":"290.1","Tissue RNA - lymph node [nTPM]":"176.4","Tissue RNA - medulla oblongata [nTPM]":"258.4","Tissue RNA - midbrain [nTPM]":"257.8","Tissue RNA - ovary [nTPM]":"136.1","Tissue RNA - pancreas [nTPM]":"116.2","Tissue RNA - parathyroid gland [nTPM]":"154.4","Tissue RNA - pituitary gland [nTPM]":"70.1","Tissue RNA - placenta [nTPM]":"132.1","Tissue RNA - pons [nTPM]":"259.6","Tissue RNA - prostate [nTPM]":"137.3","Tissue RNA - rectum [nTPM]":"194.7","Tissue RNA - retina [nTPM]":"78.9","Tissue RNA - salivary gland [nTPM]":"738.3","Tissue RNA - seminal vesicle [nTPM]":"138.6","Tissue RNA - skeletal muscle [nTPM]":"100.1","Tissue RNA - skin 1 [nTPM]":"256.9","Tissue RNA - small intestine [nTPM]":"135.6","Tissue RNA - smooth muscle [nTPM]":"110.4","Tissue RNA - spinal cord [nTPM]":"257.5","Tissue RNA - spleen [nTPM]":"125.8","Tissue RNA - stomach 1 [nTPM]":"249.9","Tissue RNA - testis [nTPM]":"71.7","Tissue RNA - thalamus [nTPM]":"262.8","Tissue RNA - thymus [nTPM]":"268.2","Tissue RNA - thyroid gland [nTPM]":"147.9","Tissue RNA - tongue [nTPM]":"197.4","Tissue RNA - tonsil [nTPM]":"1484.9","Tissue RNA - urinary bladder [nTPM]":"611.8","Tissue RNA - vagina [nTPM]":"1001.9","Tissue RNA - white matter [nTPM]":"262.9","Cell RNA - A-431 [nTPM]":"1573.6","Cell RNA - A549 [nTPM]":"495.5","Cell RNA - AF22 [nTPM]":"146.3","Cell RNA - AN3-CA [nTPM]":"188.1","Cell RNA - ASC diff [nTPM]":"874.5","Cell RNA - ASC TERT1 [nTPM]":"742.6","Cell RNA - BEWO [nTPM]":"379.6","Cell RNA - BJ [nTPM]":"310.1","Cell RNA - BJ hTERT+ [nTPM]":"431.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"230.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"230.6","Cell RNA - CACO-2 [nTPM]":"401.6","Cell RNA - CAPAN-2 [nTPM]":"868.6","Cell RNA - Daudi [nTPM]":"123.0","Cell RNA - EFO-21 [nTPM]":"245.8","Cell RNA - fHDF\/TERT166 [nTPM]":"570.1","Cell RNA - GAMG [nTPM]":"1814.0","Cell RNA - HaCaT [nTPM]":"260.5","Cell RNA - HAP1 [nTPM]":"384.4","Cell RNA - HBEC3-KT [nTPM]":"405.7","Cell RNA - HBF TERT88 [nTPM]":"153.5","Cell RNA - HDLM-2 [nTPM]":"529.0","Cell RNA - HEK 293 [nTPM]":"388.4","Cell RNA - HEL [nTPM]":"332.4","Cell RNA - HeLa [nTPM]":"385.3","Cell RNA - Hep G2 [nTPM]":"473.8","Cell RNA - HHSteC [nTPM]":"753.0","Cell RNA - HL-60 [nTPM]":"85.5","Cell RNA - HMC-1 [nTPM]":"267.1","Cell RNA - HSkMC [nTPM]":"754.5","Cell RNA - hTCEpi [nTPM]":"439.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"621.2","Cell RNA - hTERT-HME1 [nTPM]":"314.7","Cell RNA - hTERT-RPE1 [nTPM]":"389.3","Cell RNA - HUVEC TERT2 [nTPM]":"331.2","Cell RNA - JURKAT [nTPM]":"111.8","Cell RNA - K-562 [nTPM]":"276.9","Cell RNA - Karpas-707 [nTPM]":"681.1","Cell RNA - LHCN-M2 [nTPM]":"359.7","Cell RNA - MCF7 [nTPM]":"431.4","Cell RNA - MOLT-4 [nTPM]":"100.1","Cell RNA - NB-4 [nTPM]":"267.6","Cell RNA - NTERA-2 [nTPM]":"336.0","Cell RNA - OE19 [nTPM]":"1052.6","Cell RNA - PC-3 [nTPM]":"791.5","Cell RNA - REH [nTPM]":"169.7","Cell RNA - RH-30 [nTPM]":"80.5","Cell RNA - RPMI-8226 [nTPM]":"1472.0","Cell RNA - RPTEC TERT1 [nTPM]":"669.1","Cell RNA - RT4 [nTPM]":"2798.2","Cell RNA - SCLC-21H [nTPM]":"141.8","Cell RNA - SH-SY5Y [nTPM]":"121.6","Cell RNA - SiHa [nTPM]":"420.2","Cell RNA - SK-BR-3 [nTPM]":"229.2","Cell RNA - SK-MEL-30 [nTPM]":"928.8","Cell RNA - SuSa [nTPM]":"75.7","Cell RNA - T-47d [nTPM]":"210.4","Cell RNA - THP-1 [nTPM]":"214.0","Cell RNA - TIME [nTPM]":"426.3","Cell RNA - U-138 MG [nTPM]":"347.7","Cell RNA - U-2 OS [nTPM]":"162.7","Cell RNA - U-2197 [nTPM]":"305.5","Cell RNA - U-251 MG [nTPM]":"211.8","Cell RNA - U-266\/70 [nTPM]":"148.5","Cell RNA - U-266\/84 [nTPM]":"347.4","Cell RNA - U-698 [nTPM]":"251.1","Cell RNA - U-87 MG [nTPM]":"1432.5","Cell RNA - U-937 [nTPM]":"430.2","Cell RNA - WM-115 [nTPM]":"242.3","Blood RNA - basophil [nTPM]":"390.1","Blood RNA - classical monocyte [nTPM]":"505.5","Blood RNA - eosinophil [nTPM]":"313.1","Blood RNA - gdT-cell [nTPM]":"242.9","Blood RNA - intermediate monocyte [nTPM]":"840.3","Blood RNA - MAIT T-cell [nTPM]":"224.5","Blood RNA - memory B-cell [nTPM]":"198.5","Blood RNA - memory CD4 T-cell [nTPM]":"315.4","Blood RNA - memory CD8 T-cell [nTPM]":"255.4","Blood RNA - myeloid DC [nTPM]":"766.1","Blood RNA - naive B-cell [nTPM]":"172.7","Blood RNA - naive CD4 T-cell [nTPM]":"221.0","Blood RNA - naive CD8 T-cell [nTPM]":"217.6","Blood RNA - neutrophil [nTPM]":"445.6","Blood RNA - NK-cell [nTPM]":"152.4","Blood RNA - non-classical monocyte [nTPM]":"1322.9","Blood RNA - plasmacytoid DC [nTPM]":"93.4","Blood RNA - T-reg [nTPM]":"406.9","Blood RNA - total PBMC [nTPM]":"475.2","Brain RNA - amygdala [nTPM]":"254.1","Brain RNA - basal ganglia [nTPM]":"253.6","Brain RNA - cerebellum [nTPM]":"255.4","Brain RNA - cerebral cortex [nTPM]":"314.6","Brain RNA - hippocampal formation [nTPM]":"252.8","Brain RNA - hypothalamus [nTPM]":"263.0","Brain RNA - medulla oblongata [nTPM]":"258.4","Brain RNA - midbrain [nTPM]":"257.8","Brain RNA - pons [nTPM]":"259.6","Brain RNA - spinal cord [nTPM]":"257.5","Brain RNA - thalamus [nTPM]":"262.8","Brain RNA - white matter [nTPM]":"262.9","Single Cell Type RNA - Adipocytes [nTPM]":"210.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"176.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"298.4","Single Cell Type RNA - Astrocytes [nTPM]":"43.4","Single Cell Type RNA - B-cells [nTPM]":"140.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"385.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"460.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5910.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"191.2","Single Cell Type RNA - Bipolar cells [nTPM]":"69.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"317.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"345.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"105.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"268.8","Single Cell Type RNA - Club cells [nTPM]":"4352.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"415.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"310.4","Single Cell Type RNA - dendritic cells [nTPM]":"126.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"803.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"538.1","Single Cell Type RNA - Ductal cells [nTPM]":"588.4","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"388.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"205.1","Single Cell Type RNA - Endothelial cells [nTPM]":"307.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"239.3","Single Cell Type RNA - Erythroid cells [nTPM]":"61.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"488.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1199.4","Single Cell Type RNA - Fibroblasts [nTPM]":"238.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"297.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"458.8","Single Cell Type RNA - granulocytes [nTPM]":"228.2","Single Cell Type RNA - Granulosa cells [nTPM]":"131.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"250.6","Single Cell Type RNA - Hepatocytes [nTPM]":"464.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"2827.7","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"308.6","Single Cell Type RNA - Ionocytes [nTPM]":"1462.8","Single Cell Type RNA - Kupffer cells [nTPM]":"483.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1256.2","Single Cell Type RNA - Late spermatids [nTPM]":"40.8","Single Cell Type RNA - Leydig cells [nTPM]":"381.1","Single Cell Type RNA - Macrophages [nTPM]":"806.9","Single Cell Type RNA - Melanocytes [nTPM]":"471.4","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"915.9","Single Cell Type RNA - Muller glia cells [nTPM]":"160.6","Single Cell Type RNA - NK-cells [nTPM]":"255.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"810.9","Single Cell Type RNA - Paneth cells [nTPM]":"735.6","Single Cell Type RNA - Peritubular cells [nTPM]":"330.2","Single Cell Type RNA - Plasma cells [nTPM]":"167.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"674.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"524.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"469.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1997.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"72.9","Single Cell Type RNA - Sertoli cells [nTPM]":"118.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"86.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"320.0","Single Cell Type RNA - Spermatocytes [nTPM]":"33.7","Single Cell Type RNA - Spermatogonia [nTPM]":"111.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4910.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"596.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"402.5","Single Cell Type RNA - T-cells [nTPM]":"202.8","Single Cell Type RNA - Theca cells [nTPM]":"170.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"367.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3198.3"},{"Gene":"CTC1","Gene synonym":["AAF132","C17orf68","FLJ22170"],"Ensembl":"ENSG00000178971","Gene description":"CST telomere replication complex component 1","Uniprot":["Q2NKJ3"],"Chromosome":"17","Position":"8224815-8248056","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"37.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052436"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA052436":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.49e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.8","Tissue RNA - adrenal gland [nTPM]":"11.8","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"14.7","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"18.5","Tissue RNA - breast [nTPM]":"15.9","Tissue RNA - cerebellum [nTPM]":"19.7","Tissue RNA - cerebral cortex [nTPM]":"18.8","Tissue RNA - cervix [nTPM]":"17.6","Tissue RNA - choroid plexus [nTPM]":"13.2","Tissue RNA - colon [nTPM]":"16.9","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"13.5","Tissue RNA - epididymis [nTPM]":"10.7","Tissue RNA - esophagus [nTPM]":"11.1","Tissue RNA - fallopian tube [nTPM]":"17.2","Tissue RNA - gallbladder [nTPM]":"6.9","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"13.4","Tissue RNA - hypothalamus [nTPM]":"13.4","Tissue RNA - kidney [nTPM]":"16.6","Tissue RNA - liver [nTPM]":"18.3","Tissue RNA - lung [nTPM]":"18.5","Tissue RNA - lymph node [nTPM]":"24.1","Tissue RNA - medulla oblongata [nTPM]":"13.2","Tissue RNA - midbrain [nTPM]":"13.3","Tissue RNA - ovary [nTPM]":"19.9","Tissue RNA - pancreas [nTPM]":"18.2","Tissue RNA - parathyroid gland [nTPM]":"10.4","Tissue RNA - pituitary gland [nTPM]":"21.4","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"13.3","Tissue RNA - prostate [nTPM]":"16.6","Tissue RNA - rectum [nTPM]":"10.4","Tissue RNA - retina [nTPM]":"22.2","Tissue RNA - salivary gland [nTPM]":"12.4","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"14.1","Tissue RNA - small intestine [nTPM]":"25.0","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"37.2","Tissue RNA - stomach 1 [nTPM]":"15.8","Tissue RNA - testis [nTPM]":"10.8","Tissue RNA - thalamus [nTPM]":"13.7","Tissue RNA - thymus [nTPM]":"31.2","Tissue RNA - thyroid gland [nTPM]":"18.0","Tissue RNA - tongue [nTPM]":"5.7","Tissue RNA - tonsil [nTPM]":"21.4","Tissue RNA - urinary bladder [nTPM]":"14.8","Tissue RNA - vagina [nTPM]":"13.4","Tissue RNA - white matter [nTPM]":"14.6","Cell RNA - A-431 [nTPM]":"3.0","Cell RNA - A549 [nTPM]":"6.6","Cell RNA - AF22 [nTPM]":"5.9","Cell RNA - AN3-CA [nTPM]":"5.5","Cell RNA - ASC diff [nTPM]":"18.1","Cell RNA - ASC TERT1 [nTPM]":"4.3","Cell RNA - BEWO [nTPM]":"7.2","Cell RNA - BJ [nTPM]":"3.4","Cell RNA - BJ hTERT+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.2","Cell RNA - CACO-2 [nTPM]":"5.0","Cell RNA - CAPAN-2 [nTPM]":"8.8","Cell RNA - Daudi [nTPM]":"10.8","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"10.0","Cell RNA - HAP1 [nTPM]":"7.0","Cell RNA - HBEC3-KT [nTPM]":"5.2","Cell RNA - HBF TERT88 [nTPM]":"3.0","Cell RNA - HDLM-2 [nTPM]":"8.0","Cell RNA - HEK 293 [nTPM]":"6.8","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"7.2","Cell RNA - Hep G2 [nTPM]":"6.5","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"1.7","Cell RNA - HMC-1 [nTPM]":"16.1","Cell RNA - HSkMC [nTPM]":"4.4","Cell RNA - hTCEpi [nTPM]":"5.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.3","Cell RNA - hTERT-HME1 [nTPM]":"8.6","Cell RNA - hTERT-RPE1 [nTPM]":"9.5","Cell RNA - HUVEC TERT2 [nTPM]":"8.7","Cell RNA - JURKAT [nTPM]":"15.4","Cell RNA - K-562 [nTPM]":"5.1","Cell RNA - Karpas-707 [nTPM]":"3.6","Cell RNA - LHCN-M2 [nTPM]":"3.4","Cell RNA - MCF7 [nTPM]":"3.9","Cell RNA - MOLT-4 [nTPM]":"18.6","Cell RNA - NB-4 [nTPM]":"7.3","Cell RNA - NTERA-2 [nTPM]":"4.8","Cell RNA - OE19 [nTPM]":"9.7","Cell RNA - PC-3 [nTPM]":"1.6","Cell RNA - REH [nTPM]":"8.7","Cell RNA - RH-30 [nTPM]":"2.3","Cell RNA - RPMI-8226 [nTPM]":"6.9","Cell RNA - RPTEC TERT1 [nTPM]":"12.4","Cell RNA - RT4 [nTPM]":"7.1","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"5.9","Cell RNA - SiHa [nTPM]":"6.7","Cell RNA - SK-BR-3 [nTPM]":"8.6","Cell RNA - SK-MEL-30 [nTPM]":"6.0","Cell RNA - SuSa [nTPM]":"10.9","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"5.0","Cell RNA - TIME [nTPM]":"11.6","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"3.6","Cell RNA - U-251 MG [nTPM]":"4.0","Cell RNA - U-266\/70 [nTPM]":"7.4","Cell RNA - U-266\/84 [nTPM]":"4.7","Cell RNA - U-698 [nTPM]":"7.1","Cell RNA - U-87 MG [nTPM]":"2.9","Cell RNA - U-937 [nTPM]":"6.5","Cell RNA - WM-115 [nTPM]":"4.5","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"19.7","Brain RNA - cerebral cortex [nTPM]":"18.8","Brain RNA - hippocampal formation [nTPM]":"13.4","Brain RNA - hypothalamus [nTPM]":"13.4","Brain RNA - medulla oblongata [nTPM]":"13.2","Brain RNA - midbrain [nTPM]":"13.3","Brain RNA - pons [nTPM]":"13.3","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"13.7","Brain RNA - white matter [nTPM]":"14.6","Single Cell Type RNA - Adipocytes [nTPM]":"6.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.1","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"16.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"7.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"3.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - dendritic cells [nTPM]":"12.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"6.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.9","Single Cell Type RNA - Fibroblasts [nTPM]":"3.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.5","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"8.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"3.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"5.6","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.4","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.1","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - T-cells [nTPM]":"10.3","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.5","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"CTLA4","Gene synonym":["CD","CD152","CELIAC3","CTLA-4","GSE","IDDM12"],"Ensembl":"ENSG00000163599","Gene description":"Cytotoxic T-lymphocyte associated protein 4","Uniprot":["P16410"],"Chromosome":"2","Position":"203867771-203873965","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Diabetes mellitus","Disease variant","FDA approved drug targets","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"37.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"T-cells":"41.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"T-reg":"44.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"445","RNA blood lineage specific nTPM":{"T-cells":"44.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"1.5","SK-MEL-30":"3.0","U-266\/70":"4.3","U-266\/84":"13.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.48e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"18.5","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"37.4","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"6.2","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"17.0","Tissue RNA - urinary bladder [nTPM]":"5.8","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"4.3","Cell RNA - U-266\/84 [nTPM]":"13.5","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"44.5","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"41.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CTNNA1","Gene synonym":["CAP102"],"Ensembl":"ENSG00000044115","Gene description":"Catenin alpha 1","Uniprot":["P35221"],"Chromosome":"5","Position":"138610967-138935034","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB021089","HPA046119","HPA063535"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"57000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB021089":"AB_10123543","HPA046119":"AB_2679547","HPA063535":"AB_2685033"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.34e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"144.4","Tissue RNA - adrenal gland [nTPM]":"137.1","Tissue RNA - amygdala [nTPM]":"88.3","Tissue RNA - appendix [nTPM]":"65.9","Tissue RNA - basal ganglia [nTPM]":"110.4","Tissue RNA - bone marrow [nTPM]":"33.1","Tissue RNA - breast [nTPM]":"126.4","Tissue RNA - cerebellum [nTPM]":"102.9","Tissue RNA - cerebral cortex [nTPM]":"100.6","Tissue RNA - cervix [nTPM]":"110.9","Tissue RNA - choroid plexus [nTPM]":"103.2","Tissue RNA - colon [nTPM]":"155.8","Tissue RNA - duodenum [nTPM]":"115.5","Tissue RNA - endometrium 1 [nTPM]":"99.2","Tissue RNA - epididymis [nTPM]":"115.7","Tissue RNA - esophagus [nTPM]":"208.9","Tissue RNA - fallopian tube [nTPM]":"113.4","Tissue RNA - gallbladder [nTPM]":"95.6","Tissue RNA - heart muscle [nTPM]":"190.7","Tissue RNA - hippocampal formation [nTPM]":"83.7","Tissue RNA - hypothalamus [nTPM]":"91.3","Tissue RNA - kidney [nTPM]":"151.8","Tissue RNA - liver [nTPM]":"82.4","Tissue RNA - lung [nTPM]":"134.4","Tissue RNA - lymph node [nTPM]":"35.6","Tissue RNA - medulla oblongata [nTPM]":"106.8","Tissue RNA - midbrain [nTPM]":"99.4","Tissue RNA - ovary [nTPM]":"101.5","Tissue RNA - pancreas [nTPM]":"83.8","Tissue RNA - parathyroid gland [nTPM]":"120.4","Tissue RNA - pituitary gland [nTPM]":"54.3","Tissue RNA - placenta [nTPM]":"124.6","Tissue RNA - pons [nTPM]":"105.2","Tissue RNA - prostate [nTPM]":"96.3","Tissue RNA - rectum [nTPM]":"122.9","Tissue RNA - retina [nTPM]":"54.0","Tissue RNA - salivary gland [nTPM]":"127.7","Tissue RNA - seminal vesicle [nTPM]":"104.0","Tissue RNA - skeletal muscle [nTPM]":"87.1","Tissue RNA - skin 1 [nTPM]":"140.6","Tissue RNA - small intestine [nTPM]":"115.2","Tissue RNA - smooth muscle [nTPM]":"115.5","Tissue RNA - spinal cord [nTPM]":"95.9","Tissue RNA - spleen [nTPM]":"66.0","Tissue RNA - stomach 1 [nTPM]":"125.3","Tissue RNA - testis [nTPM]":"35.0","Tissue RNA - thalamus [nTPM]":"100.2","Tissue RNA - thymus [nTPM]":"33.0","Tissue RNA - thyroid gland [nTPM]":"122.9","Tissue RNA - tongue [nTPM]":"62.0","Tissue RNA - tonsil [nTPM]":"69.3","Tissue RNA - urinary bladder [nTPM]":"126.8","Tissue RNA - vagina [nTPM]":"126.3","Tissue RNA - white matter [nTPM]":"139.0","Cell RNA - A-431 [nTPM]":"225.3","Cell RNA - A549 [nTPM]":"161.1","Cell RNA - AF22 [nTPM]":"237.9","Cell RNA - AN3-CA [nTPM]":"353.6","Cell RNA - ASC diff [nTPM]":"202.2","Cell RNA - ASC TERT1 [nTPM]":"220.8","Cell RNA - BEWO [nTPM]":"362.0","Cell RNA - BJ [nTPM]":"222.0","Cell RNA - BJ hTERT+ [nTPM]":"277.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"208.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"261.1","Cell RNA - CACO-2 [nTPM]":"337.9","Cell RNA - CAPAN-2 [nTPM]":"297.4","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"182.9","Cell RNA - fHDF\/TERT166 [nTPM]":"334.3","Cell RNA - GAMG [nTPM]":"228.0","Cell RNA - HaCaT [nTPM]":"167.7","Cell RNA - HAP1 [nTPM]":"165.9","Cell RNA - HBEC3-KT [nTPM]":"366.0","Cell RNA - HBF TERT88 [nTPM]":"240.0","Cell RNA - HDLM-2 [nTPM]":"129.6","Cell RNA - HEK 293 [nTPM]":"144.0","Cell RNA - HEL [nTPM]":"94.3","Cell RNA - HeLa [nTPM]":"245.7","Cell RNA - Hep G2 [nTPM]":"206.5","Cell RNA - HHSteC [nTPM]":"243.6","Cell RNA - HL-60 [nTPM]":"1.7","Cell RNA - HMC-1 [nTPM]":"88.2","Cell RNA - HSkMC [nTPM]":"140.5","Cell RNA - hTCEpi [nTPM]":"286.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"249.1","Cell RNA - hTERT-HME1 [nTPM]":"269.6","Cell RNA - hTERT-RPE1 [nTPM]":"230.6","Cell RNA - HUVEC TERT2 [nTPM]":"397.7","Cell RNA - JURKAT [nTPM]":"66.0","Cell RNA - K-562 [nTPM]":"52.9","Cell RNA - Karpas-707 [nTPM]":"94.3","Cell RNA - LHCN-M2 [nTPM]":"227.2","Cell RNA - MCF7 [nTPM]":"199.4","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"28.9","Cell RNA - NTERA-2 [nTPM]":"96.2","Cell RNA - OE19 [nTPM]":"237.4","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"88.8","Cell RNA - RH-30 [nTPM]":"138.0","Cell RNA - RPMI-8226 [nTPM]":"135.7","Cell RNA - RPTEC TERT1 [nTPM]":"441.9","Cell RNA - RT4 [nTPM]":"295.5","Cell RNA - SCLC-21H [nTPM]":"94.9","Cell RNA - SH-SY5Y [nTPM]":"124.8","Cell RNA - SiHa [nTPM]":"409.7","Cell RNA - SK-BR-3 [nTPM]":"568.2","Cell RNA - SK-MEL-30 [nTPM]":"344.3","Cell RNA - SuSa [nTPM]":"503.4","Cell RNA - T-47d [nTPM]":"201.5","Cell RNA - THP-1 [nTPM]":"64.4","Cell RNA - TIME [nTPM]":"341.1","Cell RNA - U-138 MG [nTPM]":"217.1","Cell RNA - U-2 OS [nTPM]":"117.4","Cell RNA - U-2197 [nTPM]":"136.5","Cell RNA - U-251 MG [nTPM]":"156.5","Cell RNA - U-266\/70 [nTPM]":"33.8","Cell RNA - U-266\/84 [nTPM]":"69.9","Cell RNA - U-698 [nTPM]":"13.5","Cell RNA - U-87 MG [nTPM]":"207.0","Cell RNA - U-937 [nTPM]":"40.3","Cell RNA - WM-115 [nTPM]":"286.7","Blood RNA - basophil [nTPM]":"5.1","Blood RNA - classical monocyte [nTPM]":"37.8","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"5.8","Blood RNA - intermediate monocyte [nTPM]":"46.4","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"32.3","Blood RNA - naive B-cell [nTPM]":"6.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"20.9","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"46.8","Blood RNA - plasmacytoid DC [nTPM]":"7.9","Blood RNA - T-reg [nTPM]":"11.1","Blood RNA - total PBMC [nTPM]":"17.8","Brain RNA - amygdala [nTPM]":"88.3","Brain RNA - basal ganglia [nTPM]":"110.4","Brain RNA - cerebellum [nTPM]":"102.9","Brain RNA - cerebral cortex [nTPM]":"100.6","Brain RNA - hippocampal formation [nTPM]":"83.7","Brain RNA - hypothalamus [nTPM]":"91.3","Brain RNA - medulla oblongata [nTPM]":"106.8","Brain RNA - midbrain [nTPM]":"99.4","Brain RNA - pons [nTPM]":"105.2","Brain RNA - spinal cord [nTPM]":"95.9","Brain RNA - thalamus [nTPM]":"100.2","Brain RNA - white matter [nTPM]":"139.0","Single Cell Type RNA - Adipocytes [nTPM]":"137.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"259.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"161.0","Single Cell Type RNA - Astrocytes [nTPM]":"57.1","Single Cell Type RNA - B-cells [nTPM]":"19.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"78.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"119.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"134.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"82.0","Single Cell Type RNA - Bipolar cells [nTPM]":"7.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"74.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"52.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"230.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"87.2","Single Cell Type RNA - Club cells [nTPM]":"201.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"121.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"124.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"320.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"68.4","Single Cell Type RNA - Ductal cells [nTPM]":"184.9","Single Cell Type RNA - Early spermatids [nTPM]":"17.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"158.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.9","Single Cell Type RNA - Endothelial cells [nTPM]":"141.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"51.0","Single Cell Type RNA - Erythroid cells [nTPM]":"41.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"175.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"137.8","Single Cell Type RNA - Fibroblasts [nTPM]":"97.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"167.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"206.9","Single Cell Type RNA - granulocytes [nTPM]":"40.5","Single Cell Type RNA - Granulosa cells [nTPM]":"83.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"92.4","Single Cell Type RNA - Hepatocytes [nTPM]":"66.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"92.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"139.0","Single Cell Type RNA - Ionocytes [nTPM]":"87.5","Single Cell Type RNA - Kupffer cells [nTPM]":"80.5","Single Cell Type RNA - Langerhans cells [nTPM]":"80.9","Single Cell Type RNA - Late spermatids [nTPM]":"23.6","Single Cell Type RNA - Leydig cells [nTPM]":"77.9","Single Cell Type RNA - Macrophages [nTPM]":"77.9","Single Cell Type RNA - Melanocytes [nTPM]":"78.2","Single Cell Type RNA - Microglial cells [nTPM]":"104.0","Single Cell Type RNA - monocytes [nTPM]":"158.5","Single Cell Type RNA - Muller glia cells [nTPM]":"46.2","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"159.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"328.7","Single Cell Type RNA - Paneth cells [nTPM]":"201.4","Single Cell Type RNA - Peritubular cells [nTPM]":"84.7","Single Cell Type RNA - Plasma cells [nTPM]":"24.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"128.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"165.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"140.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"210.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.5","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"74.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"109.1","Single Cell Type RNA - Spermatocytes [nTPM]":"18.1","Single Cell Type RNA - Spermatogonia [nTPM]":"21.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"111.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"77.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"189.9","Single Cell Type RNA - T-cells [nTPM]":"20.4","Single Cell Type RNA - Theca cells [nTPM]":"44.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"130.6","Single Cell Type RNA - Urothelial cells [nTPM]":"181.4"},{"Gene":"CUX2","Gene synonym":["CDP2","CUTL2","KIAA0293"],"Ensembl":"ENSG00000111249","Gene description":"Cut like homeobox 2","Uniprot":["O14529"],"Chromosome":"12","Position":"111034165-111350554","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"20.6","choroid plexus":"25.7","liver":"20.4","prostate":"11.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"28.1","Excitatory neurons":"175.4","Hepatocytes":"50.9","Horizontal cells":"26.9","Inhibitory neurons":"72.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"5.2","prostate cancer":"11.2"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"20.6"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"70","RNA blood cell specific nTPM":{"plasmacytoid DC":"6.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"70","RNA blood lineage specific nTPM":{"dendritic cells":"6.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"6.6","HDLM-2":"2.9","hTERT-HME1":"3.5","SCLC-21H":"6.5","SH-SY5Y":"14.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"20.6","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"25.7","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"20.4","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"11.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"6.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.9","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"1.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"3.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"6.5","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.7","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"6.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"20.6","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"28.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"175.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"50.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"72.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"CWF19L1","Gene synonym":["FLJ10998","hDrn1"],"Ensembl":"ENSG00000095485","Gene description":"CWF19 like cell cycle control factor 1","Uniprot":["Q69YN2"],"Chromosome":"10","Position":"100232298-100267680","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036889","HPA036890"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA036889":"AB_10670928","HPA036890":"AB_10696789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.90e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.1","Tissue RNA - adrenal gland [nTPM]":"6.9","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"18.8","Tissue RNA - breast [nTPM]":"11.6","Tissue RNA - cerebellum [nTPM]":"7.5","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"7.2","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"6.9","Tissue RNA - fallopian tube [nTPM]":"8.7","Tissue RNA - gallbladder [nTPM]":"6.7","Tissue RNA - heart muscle [nTPM]":"7.4","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"6.5","Tissue RNA - kidney [nTPM]":"7.8","Tissue RNA - liver [nTPM]":"8.2","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"16.4","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"10.3","Tissue RNA - pancreas [nTPM]":"8.0","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"6.1","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"6.3","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"10.3","Tissue RNA - salivary gland [nTPM]":"8.6","Tissue RNA - seminal vesicle [nTPM]":"6.5","Tissue RNA - skeletal muscle [nTPM]":"10.1","Tissue RNA - skin 1 [nTPM]":"11.2","Tissue RNA - small intestine [nTPM]":"8.1","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"11.8","Tissue RNA - stomach 1 [nTPM]":"6.6","Tissue RNA - testis [nTPM]":"14.3","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"14.8","Tissue RNA - thyroid gland [nTPM]":"8.1","Tissue RNA - tongue [nTPM]":"10.2","Tissue RNA - tonsil [nTPM]":"16.9","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"8.4","Cell RNA - A-431 [nTPM]":"29.1","Cell RNA - A549 [nTPM]":"18.8","Cell RNA - AF22 [nTPM]":"18.7","Cell RNA - AN3-CA [nTPM]":"29.2","Cell RNA - ASC diff [nTPM]":"9.1","Cell RNA - ASC TERT1 [nTPM]":"10.8","Cell RNA - BEWO [nTPM]":"20.7","Cell RNA - BJ [nTPM]":"17.2","Cell RNA - BJ hTERT+ [nTPM]":"23.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"37.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.6","Cell RNA - CACO-2 [nTPM]":"21.5","Cell RNA - CAPAN-2 [nTPM]":"22.6","Cell RNA - Daudi [nTPM]":"30.5","Cell RNA - EFO-21 [nTPM]":"19.4","Cell RNA - fHDF\/TERT166 [nTPM]":"16.6","Cell RNA - GAMG [nTPM]":"16.3","Cell RNA - HaCaT [nTPM]":"27.9","Cell RNA - HAP1 [nTPM]":"42.2","Cell RNA - HBEC3-KT [nTPM]":"24.9","Cell RNA - HBF TERT88 [nTPM]":"39.6","Cell RNA - HDLM-2 [nTPM]":"19.4","Cell RNA - HEK 293 [nTPM]":"20.8","Cell RNA - HEL [nTPM]":"17.5","Cell RNA - HeLa [nTPM]":"15.8","Cell RNA - Hep G2 [nTPM]":"20.6","Cell RNA - HHSteC [nTPM]":"15.8","Cell RNA - HL-60 [nTPM]":"44.7","Cell RNA - HMC-1 [nTPM]":"19.6","Cell RNA - HSkMC [nTPM]":"15.2","Cell RNA - hTCEpi [nTPM]":"10.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.0","Cell RNA - hTERT-HME1 [nTPM]":"26.2","Cell RNA - hTERT-RPE1 [nTPM]":"14.2","Cell RNA - HUVEC TERT2 [nTPM]":"26.6","Cell RNA - JURKAT [nTPM]":"30.8","Cell RNA - K-562 [nTPM]":"20.7","Cell RNA - Karpas-707 [nTPM]":"26.8","Cell RNA - LHCN-M2 [nTPM]":"21.9","Cell RNA - MCF7 [nTPM]":"18.3","Cell RNA - MOLT-4 [nTPM]":"36.2","Cell RNA - NB-4 [nTPM]":"32.4","Cell RNA - NTERA-2 [nTPM]":"14.7","Cell RNA - OE19 [nTPM]":"15.0","Cell RNA - PC-3 [nTPM]":"23.2","Cell RNA - REH [nTPM]":"12.6","Cell RNA - RH-30 [nTPM]":"29.2","Cell RNA - RPMI-8226 [nTPM]":"21.2","Cell RNA - RPTEC TERT1 [nTPM]":"15.0","Cell RNA - RT4 [nTPM]":"16.5","Cell RNA - SCLC-21H [nTPM]":"9.4","Cell RNA - SH-SY5Y [nTPM]":"16.8","Cell RNA - SiHa [nTPM]":"20.6","Cell RNA - SK-BR-3 [nTPM]":"10.3","Cell RNA - SK-MEL-30 [nTPM]":"26.0","Cell RNA - SuSa [nTPM]":"12.6","Cell RNA - T-47d [nTPM]":"37.3","Cell RNA - THP-1 [nTPM]":"19.1","Cell RNA - TIME [nTPM]":"18.6","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"21.5","Cell RNA - U-2197 [nTPM]":"18.3","Cell RNA - U-251 MG [nTPM]":"32.8","Cell RNA - U-266\/70 [nTPM]":"23.9","Cell RNA - U-266\/84 [nTPM]":"29.6","Cell RNA - U-698 [nTPM]":"17.9","Cell RNA - U-87 MG [nTPM]":"20.1","Cell RNA - U-937 [nTPM]":"39.1","Cell RNA - WM-115 [nTPM]":"11.4","Blood RNA - basophil [nTPM]":"10.0","Blood RNA - classical monocyte [nTPM]":"17.0","Blood RNA - eosinophil [nTPM]":"22.7","Blood RNA - gdT-cell [nTPM]":"12.8","Blood RNA - intermediate monocyte [nTPM]":"15.9","Blood RNA - MAIT T-cell [nTPM]":"16.3","Blood RNA - memory B-cell [nTPM]":"14.0","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"14.4","Blood RNA - myeloid DC [nTPM]":"14.9","Blood RNA - naive B-cell [nTPM]":"13.0","Blood RNA - naive CD4 T-cell [nTPM]":"14.9","Blood RNA - naive CD8 T-cell [nTPM]":"15.0","Blood RNA - neutrophil [nTPM]":"9.6","Blood RNA - NK-cell [nTPM]":"18.1","Blood RNA - non-classical monocyte [nTPM]":"14.7","Blood RNA - plasmacytoid DC [nTPM]":"6.8","Blood RNA - T-reg [nTPM]":"17.7","Blood RNA - total PBMC [nTPM]":"13.8","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"7.5","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"6.5","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"6.3","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"8.4","Single Cell Type RNA - Adipocytes [nTPM]":"8.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"16.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"9.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"11.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - dendritic cells [nTPM]":"13.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.0","Single Cell Type RNA - Early spermatids [nTPM]":"23.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.4","Single Cell Type RNA - Endothelial cells [nTPM]":"8.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.3","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"5.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.5","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.1","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"11.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"15.5","Single Cell Type RNA - Muller glia cells [nTPM]":"5.1","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.2","Single Cell Type RNA - Paneth cells [nTPM]":"6.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"11.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.9","Single Cell Type RNA - Spermatocytes [nTPM]":"18.4","Single Cell Type RNA - Spermatogonia [nTPM]":"12.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.4"},{"Gene":"CX3CR1","Gene synonym":["CCRL1","CMKBRL1","CMKDR1","GPR13","V28"],"Ensembl":"ENSG00000168329","Gene description":"C-X3-C motif chemokine receptor 1","Uniprot":["P49238"],"Chromosome":"3","Position":"39263495-39281735","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Age-related macular degeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"26.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Microglial cells":"177.1","NK-cells":"350.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"21.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"449.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"21","RNA cell line specific nTPM":{"RPMI-8226":"589.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032478","HPA046587"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB032478":"AB_638830","HPA046587":"AB_2679708"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.3","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"6.4","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"5.1","Tissue RNA - cerebellum [nTPM]":"8.6","Tissue RNA - cerebral cortex [nTPM]":"6.0","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"2.7","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"8.4","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"9.9","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"17.3","Tissue RNA - midbrain [nTPM]":"14.8","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"4.5","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"7.2","Tissue RNA - skeletal muscle [nTPM]":"6.5","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"21.5","Tissue RNA - spleen [nTPM]":"11.9","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"17.4","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"2.4","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"26.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"6.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"24.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"589.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"8.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"16.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"28.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"7.7","Blood RNA - classical monocyte [nTPM]":"99.6","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"264.0","Blood RNA - intermediate monocyte [nTPM]":"261.2","Blood RNA - MAIT T-cell [nTPM]":"3.4","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"55.9","Blood RNA - memory CD8 T-cell [nTPM]":"145.2","Blood RNA - myeloid DC [nTPM]":"94.4","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"19.0","Blood RNA - naive CD8 T-cell [nTPM]":"122.4","Blood RNA - neutrophil [nTPM]":"20.8","Blood RNA - NK-cell [nTPM]":"39.7","Blood RNA - non-classical monocyte [nTPM]":"449.2","Blood RNA - plasmacytoid DC [nTPM]":"7.1","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"232.7","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"6.4","Brain RNA - cerebellum [nTPM]":"8.6","Brain RNA - cerebral cortex [nTPM]":"6.0","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"8.4","Brain RNA - medulla oblongata [nTPM]":"17.3","Brain RNA - midbrain [nTPM]":"14.8","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"21.5","Brain RNA - thalamus [nTPM]":"17.4","Brain RNA - white matter [nTPM]":"26.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"44.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"15.0","Single Cell Type RNA - Langerhans cells [nTPM]":"28.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"43.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"177.1","Single Cell Type RNA - monocytes [nTPM]":"50.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"350.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"22.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CYFIP2","Gene synonym":["PIR121"],"Ensembl":"ENSG00000055163","Gene description":"Cytoplasmic FMR1 interacting protein 2","Uniprot":["Q96F07"],"Chromosome":"5","Position":"157266079-157395595","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"112.2","kidney":"139.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"133.5","Collecting duct cells":"158.2","Distal tubular cells":"174.1","Excitatory neurons":"117.7","Inhibitory neurons":"147.5","Oligodendrocyte precursor cells":"120.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"202.4","JURKAT":"145.2","MOLT-4":"204.8","U-266\/70":"153.6","U-698":"142.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB055519","HPA068106","HPA071459"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB055519":null,"HPA068106":"AB_2685955","HPA071459":"AB_2686400"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.42e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.21e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.2","Tissue RNA - adrenal gland [nTPM]":"12.3","Tissue RNA - amygdala [nTPM]":"61.0","Tissue RNA - appendix [nTPM]":"30.8","Tissue RNA - basal ganglia [nTPM]":"54.4","Tissue RNA - bone marrow [nTPM]":"55.5","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"23.6","Tissue RNA - cerebral cortex [nTPM]":"103.8","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"16.3","Tissue RNA - colon [nTPM]":"8.9","Tissue RNA - duodenum [nTPM]":"6.3","Tissue RNA - endometrium 1 [nTPM]":"6.6","Tissue RNA - epididymis [nTPM]":"25.1","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"9.2","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"10.4","Tissue RNA - hippocampal formation [nTPM]":"112.2","Tissue RNA - hypothalamus [nTPM]":"25.6","Tissue RNA - kidney [nTPM]":"139.9","Tissue RNA - liver [nTPM]":"18.3","Tissue RNA - lung [nTPM]":"12.2","Tissue RNA - lymph node [nTPM]":"57.1","Tissue RNA - medulla oblongata [nTPM]":"8.4","Tissue RNA - midbrain [nTPM]":"33.4","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"7.1","Tissue RNA - parathyroid gland [nTPM]":"64.9","Tissue RNA - pituitary gland [nTPM]":"40.1","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"5.8","Tissue RNA - rectum [nTPM]":"9.8","Tissue RNA - retina [nTPM]":"35.4","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"17.5","Tissue RNA - smooth muscle [nTPM]":"5.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"35.0","Tissue RNA - stomach 1 [nTPM]":"20.9","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"67.7","Tissue RNA - thymus [nTPM]":"85.9","Tissue RNA - thyroid gland [nTPM]":"9.9","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"55.3","Tissue RNA - urinary bladder [nTPM]":"8.3","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"37.7","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"31.8","Cell RNA - AF22 [nTPM]":"47.3","Cell RNA - AN3-CA [nTPM]":"28.8","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"81.5","Cell RNA - BJ [nTPM]":"6.1","Cell RNA - BJ hTERT+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.8","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"202.4","Cell RNA - EFO-21 [nTPM]":"14.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.4","Cell RNA - GAMG [nTPM]":"7.4","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"38.0","Cell RNA - HBEC3-KT [nTPM]":"27.1","Cell RNA - HBF TERT88 [nTPM]":"5.8","Cell RNA - HDLM-2 [nTPM]":"48.8","Cell RNA - HEK 293 [nTPM]":"60.8","Cell RNA - HEL [nTPM]":"28.4","Cell RNA - HeLa [nTPM]":"42.3","Cell RNA - Hep G2 [nTPM]":"24.9","Cell RNA - HHSteC [nTPM]":"4.1","Cell RNA - HL-60 [nTPM]":"29.1","Cell RNA - HMC-1 [nTPM]":"71.8","Cell RNA - HSkMC [nTPM]":"5.4","Cell RNA - hTCEpi [nTPM]":"10.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.1","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"18.8","Cell RNA - HUVEC TERT2 [nTPM]":"8.8","Cell RNA - JURKAT [nTPM]":"145.2","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"81.1","Cell RNA - LHCN-M2 [nTPM]":"7.0","Cell RNA - MCF7 [nTPM]":"7.7","Cell RNA - MOLT-4 [nTPM]":"204.8","Cell RNA - NB-4 [nTPM]":"5.5","Cell RNA - NTERA-2 [nTPM]":"22.3","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"8.5","Cell RNA - REH [nTPM]":"50.6","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"102.3","Cell RNA - RPTEC TERT1 [nTPM]":"24.5","Cell RNA - RT4 [nTPM]":"30.2","Cell RNA - SCLC-21H [nTPM]":"70.5","Cell RNA - SH-SY5Y [nTPM]":"27.4","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"28.3","Cell RNA - SK-MEL-30 [nTPM]":"4.6","Cell RNA - SuSa [nTPM]":"46.8","Cell RNA - T-47d [nTPM]":"19.9","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"11.3","Cell RNA - U-138 MG [nTPM]":"2.0","Cell RNA - U-2 OS [nTPM]":"21.4","Cell RNA - U-2197 [nTPM]":"7.1","Cell RNA - U-251 MG [nTPM]":"5.4","Cell RNA - U-266\/70 [nTPM]":"153.6","Cell RNA - U-266\/84 [nTPM]":"40.2","Cell RNA - U-698 [nTPM]":"142.8","Cell RNA - U-87 MG [nTPM]":"21.4","Cell RNA - U-937 [nTPM]":"33.5","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"64.8","Blood RNA - classical monocyte [nTPM]":"12.6","Blood RNA - eosinophil [nTPM]":"90.1","Blood RNA - gdT-cell [nTPM]":"85.9","Blood RNA - intermediate monocyte [nTPM]":"57.4","Blood RNA - MAIT T-cell [nTPM]":"61.0","Blood RNA - memory B-cell [nTPM]":"35.8","Blood RNA - memory CD4 T-cell [nTPM]":"60.6","Blood RNA - memory CD8 T-cell [nTPM]":"75.7","Blood RNA - myeloid DC [nTPM]":"17.8","Blood RNA - naive B-cell [nTPM]":"35.9","Blood RNA - naive CD4 T-cell [nTPM]":"63.2","Blood RNA - naive CD8 T-cell [nTPM]":"73.2","Blood RNA - neutrophil [nTPM]":"41.0","Blood RNA - NK-cell [nTPM]":"53.9","Blood RNA - non-classical monocyte [nTPM]":"133.7","Blood RNA - plasmacytoid DC [nTPM]":"43.9","Blood RNA - T-reg [nTPM]":"53.5","Blood RNA - total PBMC [nTPM]":"78.0","Brain RNA - amygdala [nTPM]":"61.0","Brain RNA - basal ganglia [nTPM]":"54.4","Brain RNA - cerebellum [nTPM]":"23.6","Brain RNA - cerebral cortex [nTPM]":"103.8","Brain RNA - hippocampal formation [nTPM]":"112.2","Brain RNA - hypothalamus [nTPM]":"25.6","Brain RNA - medulla oblongata [nTPM]":"8.4","Brain RNA - midbrain [nTPM]":"33.4","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"67.7","Brain RNA - white matter [nTPM]":"37.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.9","Single Cell Type RNA - Astrocytes [nTPM]":"133.5","Single Cell Type RNA - B-cells [nTPM]":"76.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"62.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"7.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"158.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.2","Single Cell Type RNA - dendritic cells [nTPM]":"78.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"174.1","Single Cell Type RNA - Ductal cells [nTPM]":"9.7","Single Cell Type RNA - Early spermatids [nTPM]":"15.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.8","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"117.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"23.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"30.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.3","Single Cell Type RNA - Horizontal cells [nTPM]":"90.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"147.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.5","Single Cell Type RNA - Langerhans cells [nTPM]":"11.4","Single Cell Type RNA - Late spermatids [nTPM]":"24.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"15.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"20.3","Single Cell Type RNA - Muller glia cells [nTPM]":"14.0","Single Cell Type RNA - NK-cells [nTPM]":"101.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"120.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"41.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"55.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.0","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - T-cells [nTPM]":"88.8","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"CYP2U1","Gene synonym":["SPG49","SPG56"],"Ensembl":"ENSG00000155016","Gene description":"Cytochrome P450 family 2 subfamily U member 1","Uniprot":["Q7Z449"],"Chromosome":"4","Position":"107931549-107953461","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"lymphoid tissue":"84.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"30.2","Inhibitory neurons":"34.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"2.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041622","HPA046754","HPA064827"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA041622":"AB_2677583","HPA046754":"AB_2679787","HPA064827":"AB_2685362"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.97e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.7","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"4.5","Tissue RNA - cerebellum [nTPM]":"7.6","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"10.1","Tissue RNA - colon [nTPM]":"5.8","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"6.6","Tissue RNA - epididymis [nTPM]":"3.6","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"5.6","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"5.3","Tissue RNA - liver [nTPM]":"5.9","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"9.5","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"10.7","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"5.8","Tissue RNA - salivary gland [nTPM]":"3.4","Tissue RNA - seminal vesicle [nTPM]":"8.7","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"10.2","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"3.2","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"84.9","Tissue RNA - thyroid gland [nTPM]":"3.6","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"4.7","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"9.5","Cell RNA - A-431 [nTPM]":"4.0","Cell RNA - A549 [nTPM]":"1.9","Cell RNA - AF22 [nTPM]":"5.2","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"28.6","Cell RNA - ASC TERT1 [nTPM]":"13.4","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"16.8","Cell RNA - BJ hTERT+ [nTPM]":"25.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.7","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"2.5","Cell RNA - Daudi [nTPM]":"10.8","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"10.1","Cell RNA - GAMG [nTPM]":"7.8","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"6.4","Cell RNA - HBF TERT88 [nTPM]":"15.4","Cell RNA - HDLM-2 [nTPM]":"3.0","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"2.3","Cell RNA - HeLa [nTPM]":"3.5","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"11.3","Cell RNA - HL-60 [nTPM]":"3.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"5.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.7","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"20.8","Cell RNA - HUVEC TERT2 [nTPM]":"4.0","Cell RNA - JURKAT [nTPM]":"12.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"5.0","Cell RNA - LHCN-M2 [nTPM]":"8.4","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"11.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"4.7","Cell RNA - REH [nTPM]":"6.5","Cell RNA - RH-30 [nTPM]":"6.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.3","Cell RNA - RT4 [nTPM]":"6.7","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"7.6","Cell RNA - SiHa [nTPM]":"4.2","Cell RNA - SK-BR-3 [nTPM]":"7.3","Cell RNA - SK-MEL-30 [nTPM]":"18.6","Cell RNA - SuSa [nTPM]":"4.3","Cell RNA - T-47d [nTPM]":"3.6","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"10.6","Cell RNA - U-138 MG [nTPM]":"6.5","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"9.3","Cell RNA - U-251 MG [nTPM]":"6.9","Cell RNA - U-266\/70 [nTPM]":"21.1","Cell RNA - U-266\/84 [nTPM]":"21.2","Cell RNA - U-698 [nTPM]":"3.4","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"7.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"7.6","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"9.5","Single Cell Type RNA - Adipocytes [nTPM]":"5.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"13.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"12.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"7.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.5","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"4.7","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"3.7","Single Cell Type RNA - Muller glia cells [nTPM]":"9.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"CYP4V2","Gene synonym":["CYP4AH1"],"Ensembl":"ENSG00000145476","Gene description":"Cytochrome P450 family 4 subfamily V member 2","Uniprot":["Q6ZWL3"],"Chromosome":"4","Position":"186191567-186213463","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sensory transduction","Vision"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"113.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"103.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"15.2","SK-MEL-30":"27.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029122"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029122":"AB_10601806"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.86e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"16.4","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"2.1","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"5.6","Tissue RNA - cerebral cortex [nTPM]":"5.0","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"17.9","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"16.5","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"14.7","Tissue RNA - heart muscle [nTPM]":"9.2","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"33.9","Tissue RNA - liver [nTPM]":"113.5","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"6.0","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"15.6","Tissue RNA - parathyroid gland [nTPM]":"33.4","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"11.9","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"7.0","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"5.6","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"4.9","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"3.4","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"15.2","Cell RNA - ASC TERT1 [nTPM]":"6.3","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"9.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.9","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"13.0","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.5","Cell RNA - GAMG [nTPM]":"5.9","Cell RNA - HaCaT [nTPM]":"1.6","Cell RNA - HAP1 [nTPM]":"1.9","Cell RNA - HBEC3-KT [nTPM]":"1.7","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"6.0","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"4.7","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"5.6","Cell RNA - HL-60 [nTPM]":"2.6","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"5.8","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"6.4","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"14.3","Cell RNA - LHCN-M2 [nTPM]":"6.8","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"3.6","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"3.1","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"7.4","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"27.5","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"2.6","Cell RNA - THP-1 [nTPM]":"4.6","Cell RNA - TIME [nTPM]":"4.1","Cell RNA - U-138 MG [nTPM]":"3.6","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"3.5","Cell RNA - U-251 MG [nTPM]":"1.6","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"10.9","Cell RNA - U-937 [nTPM]":"11.0","Cell RNA - WM-115 [nTPM]":"4.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"3.1","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"5.6","Brain RNA - cerebral cortex [nTPM]":"5.0","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"6.0","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"5.6","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"9.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"31.3","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"33.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"9.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"24.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.9","Single Cell Type RNA - Erythroid cells [nTPM]":"16.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.6","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"103.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.8","Single Cell Type RNA - Langerhans cells [nTPM]":"6.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"11.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"3.5","Single Cell Type RNA - Muller glia cells [nTPM]":"52.2","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.6","Single Cell Type RNA - Paneth cells [nTPM]":"9.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"8.9","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"17.2","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.5","Single Cell Type RNA - Urothelial cells [nTPM]":"5.7"},{"Gene":"CYP7B1","Gene synonym":["SPG5A"],"Ensembl":"ENSG00000172817","Gene description":"Cytochrome P450 family 7 subfamily B member 1","Uniprot":["O75881"],"Chromosome":"8","Position":"64587763-64798737","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Intrahepatic cholestasis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"93.7","Oligodendrocyte precursor cells":"94.5","Oligodendrocytes":"119.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"basophil":"2.5","eosinophil":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"25","RNA blood lineage specific nTPM":{"granulocytes":"2.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HSkMC":"16.5","SH-SY5Y":"5.5","WM-115":"10.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017761"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017761":"AB_1847455"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.4","Tissue RNA - adrenal gland [nTPM]":"5.4","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"11.4","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"6.6","Tissue RNA - cervix [nTPM]":"5.7","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"7.3","Tissue RNA - fallopian tube [nTPM]":"2.7","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"3.6","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"6.8","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"21.5","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"11.8","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"4.2","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"11.4","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"5.6","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"4.3","Tissue RNA - spinal cord [nTPM]":"8.4","Tissue RNA - spleen [nTPM]":"9.2","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"12.2","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"3.0","Tissue RNA - white matter [nTPM]":"27.2","Cell RNA - A-431 [nTPM]":"1.5","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"16.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"5.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"10.3","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"11.4","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"6.6","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"6.8","Brain RNA - medulla oblongata [nTPM]":"11.8","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"8.4","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"27.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"93.7","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"4.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"7.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"8.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"94.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"119.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"DAB1","Gene synonym":[],"Ensembl":"ENSG00000173406","Gene description":"DAB adaptor protein 1","Uniprot":["O75553"],"Chromosome":"1","Position":"56994778-58546734","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"16.8","intestine":"22.3","seminal vesicle":"10.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Excitatory neurons":"460.3","Inhibitory neurons":"1170.3","Oligodendrocyte precursor cells":"814.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"2.1"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"T-cells":"2.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"54.0","HeLa":"18.6","NTERA-2":"23.4","RT4":"32.0","WM-115":"26.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032329","HPA052033","HPA067495"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB032329":"AB_638973","HPA052033":"AB_2681703","HPA067495":"AB_2685852"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"5.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"16.8","Tissue RNA - cerebral cortex [nTPM]":"8.8","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"1.6","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"3.9","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"10.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"22.3","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"5.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"10.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"54.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"18.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"23.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"6.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"32.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"26.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"5.3","Brain RNA - cerebellum [nTPM]":"16.8","Brain RNA - cerebral cortex [nTPM]":"8.8","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"5.1","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"30.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"23.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"460.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"5.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1170.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"814.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"101.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"DALRD3","Gene synonym":["FLJ10496"],"Ensembl":"ENSG00000178149","Gene description":"DALR anticodon binding domain containing 3","Uniprot":["Q5D0E6"],"Chromosome":"3","Position":"49015488-49022293","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"158.9","Late spermatids":"306.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036862"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA036862":"AB_10673507"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.03e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.79e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"18.5","Tissue RNA - amygdala [nTPM]":"11.2","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"14.2","Tissue RNA - cerebellum [nTPM]":"10.6","Tissue RNA - cerebral cortex [nTPM]":"12.4","Tissue RNA - cervix [nTPM]":"14.1","Tissue RNA - choroid plexus [nTPM]":"14.5","Tissue RNA - colon [nTPM]":"10.1","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"9.8","Tissue RNA - epididymis [nTPM]":"13.1","Tissue RNA - esophagus [nTPM]":"18.3","Tissue RNA - fallopian tube [nTPM]":"36.9","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"10.0","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"21.4","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"9.9","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"11.5","Tissue RNA - midbrain [nTPM]":"12.6","Tissue RNA - ovary [nTPM]":"15.2","Tissue RNA - pancreas [nTPM]":"38.7","Tissue RNA - parathyroid gland [nTPM]":"13.9","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"9.6","Tissue RNA - pons [nTPM]":"10.9","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"11.6","Tissue RNA - seminal vesicle [nTPM]":"9.5","Tissue RNA - skeletal muscle [nTPM]":"11.0","Tissue RNA - skin 1 [nTPM]":"18.8","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"12.0","Tissue RNA - spleen [nTPM]":"10.8","Tissue RNA - stomach 1 [nTPM]":"14.7","Tissue RNA - testis [nTPM]":"51.0","Tissue RNA - thalamus [nTPM]":"11.2","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"19.2","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"12.3","Tissue RNA - urinary bladder [nTPM]":"10.7","Tissue RNA - vagina [nTPM]":"11.5","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"12.0","Cell RNA - A549 [nTPM]":"16.6","Cell RNA - AF22 [nTPM]":"10.2","Cell RNA - AN3-CA [nTPM]":"20.0","Cell RNA - ASC diff [nTPM]":"28.5","Cell RNA - ASC TERT1 [nTPM]":"37.8","Cell RNA - BEWO [nTPM]":"12.4","Cell RNA - BJ [nTPM]":"9.9","Cell RNA - BJ hTERT+ [nTPM]":"27.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.8","Cell RNA - CACO-2 [nTPM]":"11.7","Cell RNA - CAPAN-2 [nTPM]":"14.9","Cell RNA - Daudi [nTPM]":"4.9","Cell RNA - EFO-21 [nTPM]":"13.7","Cell RNA - fHDF\/TERT166 [nTPM]":"27.3","Cell RNA - GAMG [nTPM]":"14.3","Cell RNA - HaCaT [nTPM]":"7.8","Cell RNA - HAP1 [nTPM]":"13.4","Cell RNA - HBEC3-KT [nTPM]":"26.1","Cell RNA - HBF TERT88 [nTPM]":"11.5","Cell RNA - HDLM-2 [nTPM]":"7.0","Cell RNA - HEK 293 [nTPM]":"9.1","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"13.9","Cell RNA - Hep G2 [nTPM]":"22.0","Cell RNA - HHSteC [nTPM]":"18.7","Cell RNA - HL-60 [nTPM]":"15.0","Cell RNA - HMC-1 [nTPM]":"10.5","Cell RNA - HSkMC [nTPM]":"25.7","Cell RNA - hTCEpi [nTPM]":"26.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.9","Cell RNA - hTERT-HME1 [nTPM]":"46.1","Cell RNA - hTERT-RPE1 [nTPM]":"42.0","Cell RNA - HUVEC TERT2 [nTPM]":"26.0","Cell RNA - JURKAT [nTPM]":"11.2","Cell RNA - K-562 [nTPM]":"4.3","Cell RNA - Karpas-707 [nTPM]":"12.0","Cell RNA - LHCN-M2 [nTPM]":"16.4","Cell RNA - MCF7 [nTPM]":"20.8","Cell RNA - MOLT-4 [nTPM]":"6.6","Cell RNA - NB-4 [nTPM]":"10.1","Cell RNA - NTERA-2 [nTPM]":"16.8","Cell RNA - OE19 [nTPM]":"25.3","Cell RNA - PC-3 [nTPM]":"15.5","Cell RNA - REH [nTPM]":"3.5","Cell RNA - RH-30 [nTPM]":"1.5","Cell RNA - RPMI-8226 [nTPM]":"35.7","Cell RNA - RPTEC TERT1 [nTPM]":"44.4","Cell RNA - RT4 [nTPM]":"19.0","Cell RNA - SCLC-21H [nTPM]":"6.5","Cell RNA - SH-SY5Y [nTPM]":"21.1","Cell RNA - SiHa [nTPM]":"10.9","Cell RNA - SK-BR-3 [nTPM]":"30.1","Cell RNA - SK-MEL-30 [nTPM]":"23.7","Cell RNA - SuSa [nTPM]":"16.8","Cell RNA - T-47d [nTPM]":"21.3","Cell RNA - THP-1 [nTPM]":"16.2","Cell RNA - TIME [nTPM]":"15.9","Cell RNA - U-138 MG [nTPM]":"6.4","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"22.6","Cell RNA - U-251 MG [nTPM]":"9.2","Cell RNA - U-266\/70 [nTPM]":"37.8","Cell RNA - U-266\/84 [nTPM]":"21.9","Cell RNA - U-698 [nTPM]":"3.0","Cell RNA - U-87 MG [nTPM]":"24.2","Cell RNA - U-937 [nTPM]":"8.3","Cell RNA - WM-115 [nTPM]":"12.9","Blood RNA - basophil [nTPM]":"12.0","Blood RNA - classical monocyte [nTPM]":"11.1","Blood RNA - eosinophil [nTPM]":"5.5","Blood RNA - gdT-cell [nTPM]":"13.9","Blood RNA - intermediate monocyte [nTPM]":"13.7","Blood RNA - MAIT T-cell [nTPM]":"25.0","Blood RNA - memory B-cell [nTPM]":"23.9","Blood RNA - memory CD4 T-cell [nTPM]":"22.4","Blood RNA - memory CD8 T-cell [nTPM]":"17.1","Blood RNA - myeloid DC [nTPM]":"11.7","Blood RNA - naive B-cell [nTPM]":"21.1","Blood RNA - naive CD4 T-cell [nTPM]":"18.7","Blood RNA - naive CD8 T-cell [nTPM]":"12.5","Blood RNA - neutrophil [nTPM]":"10.9","Blood RNA - NK-cell [nTPM]":"22.6","Blood RNA - non-classical monocyte [nTPM]":"12.8","Blood RNA - plasmacytoid DC [nTPM]":"8.1","Blood RNA - T-reg [nTPM]":"29.5","Blood RNA - total PBMC [nTPM]":"12.8","Brain RNA - amygdala [nTPM]":"11.2","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"10.6","Brain RNA - cerebral cortex [nTPM]":"12.4","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"11.5","Brain RNA - midbrain [nTPM]":"12.6","Brain RNA - pons [nTPM]":"10.9","Brain RNA - spinal cord [nTPM]":"12.0","Brain RNA - thalamus [nTPM]":"11.2","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"26.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.2","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"27.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"30.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"40.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"20.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.2","Single Cell Type RNA - dendritic cells [nTPM]":"30.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Ductal cells [nTPM]":"40.7","Single Cell Type RNA - Early spermatids [nTPM]":"158.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"61.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.5","Single Cell Type RNA - Endothelial cells [nTPM]":"16.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.1","Single Cell Type RNA - Erythroid cells [nTPM]":"11.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"39.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.0","Single Cell Type RNA - Fibroblasts [nTPM]":"19.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.6","Single Cell Type RNA - granulocytes [nTPM]":"24.7","Single Cell Type RNA - Granulosa cells [nTPM]":"32.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.2","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"12.9","Single Cell Type RNA - Langerhans cells [nTPM]":"24.5","Single Cell Type RNA - Late spermatids [nTPM]":"306.6","Single Cell Type RNA - Leydig cells [nTPM]":"24.2","Single Cell Type RNA - Macrophages [nTPM]":"16.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"23.5","Single Cell Type RNA - Muller glia cells [nTPM]":"25.8","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.5","Single Cell Type RNA - Paneth cells [nTPM]":"21.3","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"18.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"49.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"75.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.0","Single Cell Type RNA - Spermatocytes [nTPM]":"110.7","Single Cell Type RNA - Spermatogonia [nTPM]":"33.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - T-cells [nTPM]":"27.1","Single Cell Type RNA - Theca cells [nTPM]":"29.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.0","Single Cell Type RNA - Urothelial cells [nTPM]":"17.3"},{"Gene":"DARS2","Gene synonym":["FLJ10514","mtAspRS"],"Ensembl":"ENSG00000117593","Gene description":"Aspartyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q6PI48"],"Chromosome":"1","Position":"173824653-173858808","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026506","HPA026528"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA026506":"AB_1847482","HPA026528":"AB_1847483"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.74e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"9.8","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"7.5","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"11.5","Tissue RNA - colon [nTPM]":"14.6","Tissue RNA - duodenum [nTPM]":"8.7","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"3.8","Tissue RNA - kidney [nTPM]":"19.9","Tissue RNA - liver [nTPM]":"13.5","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"4.4","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"15.5","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"15.4","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"5.6","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"5.6","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"9.3","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"13.5","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"74.8","Cell RNA - A549 [nTPM]":"50.5","Cell RNA - AF22 [nTPM]":"26.3","Cell RNA - AN3-CA [nTPM]":"18.7","Cell RNA - ASC diff [nTPM]":"24.0","Cell RNA - ASC TERT1 [nTPM]":"34.2","Cell RNA - BEWO [nTPM]":"38.6","Cell RNA - BJ [nTPM]":"32.3","Cell RNA - BJ hTERT+ [nTPM]":"30.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.0","Cell RNA - CACO-2 [nTPM]":"47.5","Cell RNA - CAPAN-2 [nTPM]":"68.2","Cell RNA - Daudi [nTPM]":"41.6","Cell RNA - EFO-21 [nTPM]":"45.2","Cell RNA - fHDF\/TERT166 [nTPM]":"27.2","Cell RNA - GAMG [nTPM]":"31.3","Cell RNA - HaCaT [nTPM]":"77.5","Cell RNA - HAP1 [nTPM]":"86.6","Cell RNA - HBEC3-KT [nTPM]":"56.5","Cell RNA - HBF TERT88 [nTPM]":"66.7","Cell RNA - HDLM-2 [nTPM]":"48.6","Cell RNA - HEK 293 [nTPM]":"41.5","Cell RNA - HEL [nTPM]":"35.2","Cell RNA - HeLa [nTPM]":"22.7","Cell RNA - Hep G2 [nTPM]":"31.8","Cell RNA - HHSteC [nTPM]":"24.0","Cell RNA - HL-60 [nTPM]":"30.9","Cell RNA - HMC-1 [nTPM]":"30.8","Cell RNA - HSkMC [nTPM]":"23.2","Cell RNA - hTCEpi [nTPM]":"25.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.9","Cell RNA - hTERT-HME1 [nTPM]":"44.5","Cell RNA - hTERT-RPE1 [nTPM]":"15.4","Cell RNA - HUVEC TERT2 [nTPM]":"49.8","Cell RNA - JURKAT [nTPM]":"30.5","Cell RNA - K-562 [nTPM]":"74.7","Cell RNA - Karpas-707 [nTPM]":"31.0","Cell RNA - LHCN-M2 [nTPM]":"39.6","Cell RNA - MCF7 [nTPM]":"19.9","Cell RNA - MOLT-4 [nTPM]":"38.8","Cell RNA - NB-4 [nTPM]":"16.1","Cell RNA - NTERA-2 [nTPM]":"60.2","Cell RNA - OE19 [nTPM]":"83.0","Cell RNA - PC-3 [nTPM]":"63.2","Cell RNA - REH [nTPM]":"44.3","Cell RNA - RH-30 [nTPM]":"40.6","Cell RNA - RPMI-8226 [nTPM]":"78.2","Cell RNA - RPTEC TERT1 [nTPM]":"43.7","Cell RNA - RT4 [nTPM]":"24.9","Cell RNA - SCLC-21H [nTPM]":"40.4","Cell RNA - SH-SY5Y [nTPM]":"34.2","Cell RNA - SiHa [nTPM]":"36.3","Cell RNA - SK-BR-3 [nTPM]":"79.6","Cell RNA - SK-MEL-30 [nTPM]":"51.3","Cell RNA - SuSa [nTPM]":"47.0","Cell RNA - T-47d [nTPM]":"84.5","Cell RNA - THP-1 [nTPM]":"39.7","Cell RNA - TIME [nTPM]":"21.2","Cell RNA - U-138 MG [nTPM]":"22.9","Cell RNA - U-2 OS [nTPM]":"35.3","Cell RNA - U-2197 [nTPM]":"32.6","Cell RNA - U-251 MG [nTPM]":"52.5","Cell RNA - U-266\/70 [nTPM]":"21.7","Cell RNA - U-266\/84 [nTPM]":"60.4","Cell RNA - U-698 [nTPM]":"46.3","Cell RNA - U-87 MG [nTPM]":"13.3","Cell RNA - U-937 [nTPM]":"33.3","Cell RNA - WM-115 [nTPM]":"51.5","Blood RNA - basophil [nTPM]":"3.9","Blood RNA - classical monocyte [nTPM]":"4.4","Blood RNA - eosinophil [nTPM]":"3.3","Blood RNA - gdT-cell [nTPM]":"3.8","Blood RNA - intermediate monocyte [nTPM]":"7.0","Blood RNA - MAIT T-cell [nTPM]":"5.4","Blood RNA - memory B-cell [nTPM]":"6.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.4","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"6.4","Blood RNA - naive B-cell [nTPM]":"4.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"5.0","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"3.9","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"3.8","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"3.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.7","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.9","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.9","Single Cell Type RNA - Endothelial cells [nTPM]":"4.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.5","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"4.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.3","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"5.6","Single Cell Type RNA - Muller glia cells [nTPM]":"2.9","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"7.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"4.4","Single Cell Type RNA - Theca cells [nTPM]":"9.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"DBH","Gene synonym":["DBM"],"Ensembl":"ENSG00000123454","Gene description":"Dopamine beta-hydroxylase","Uniprot":["P09172"],"Chromosome":"9","Position":"133636363-133659329","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Catecholamine biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"adrenal gland":"272.7","brain":"236.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hepatic stellate cells":"10.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"1.7"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"pons":"236.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"346","RNA cell line specific nTPM":{"SH-SY5Y":"1826.4"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"pons and medulla":"22.1"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"26","RNA pig brain regional specific nTPM":{"pons":"18.5"},"Antibody":["HPA002130","HPA005960","HPA070789"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA002130":"AB_2666554","HPA005960":"AB_1078628","HPA070789":"AB_2686312"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.8","Tissue RNA - adrenal gland [nTPM]":"272.7","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"36.1","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"29.4","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"4.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"236.6","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"3.2","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"5.2","Cell RNA - RPMI-8226 [nTPM]":"4.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.1","Cell RNA - SH-SY5Y [nTPM]":"1826.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"29.4","Brain RNA - pons [nTPM]":"236.6","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"DCAF8","Gene synonym":["FLJ35857","H326","WDR42A"],"Ensembl":"ENSG00000132716","Gene description":"DDB1 and CUL4 associated factor 8","Uniprot":["Q5TAQ9"],"Chromosome":"1","Position":"160215715-160262549","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027218","HPA027381"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA027218":"AB_10602586","HPA027381":"AB_1858808"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.71e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.74e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Tissue RNA - adipose tissue [nTPM]":"63.3","Tissue RNA - adrenal gland [nTPM]":"62.6","Tissue RNA - amygdala [nTPM]":"35.3","Tissue RNA - appendix [nTPM]":"47.0","Tissue RNA - basal ganglia [nTPM]":"43.3","Tissue RNA - bone marrow [nTPM]":"54.6","Tissue RNA - breast [nTPM]":"60.6","Tissue RNA - cerebellum [nTPM]":"47.7","Tissue RNA - cerebral cortex [nTPM]":"52.8","Tissue RNA - cervix [nTPM]":"55.8","Tissue RNA - choroid plexus [nTPM]":"47.1","Tissue RNA - colon [nTPM]":"72.0","Tissue RNA - duodenum [nTPM]":"56.6","Tissue RNA - endometrium 1 [nTPM]":"60.4","Tissue RNA - epididymis [nTPM]":"76.2","Tissue RNA - esophagus [nTPM]":"50.2","Tissue RNA - fallopian tube [nTPM]":"58.9","Tissue RNA - gallbladder [nTPM]":"53.5","Tissue RNA - heart muscle [nTPM]":"85.1","Tissue RNA - hippocampal formation [nTPM]":"33.7","Tissue RNA - hypothalamus [nTPM]":"41.8","Tissue RNA - kidney [nTPM]":"55.8","Tissue RNA - liver [nTPM]":"103.4","Tissue RNA - lung [nTPM]":"50.9","Tissue RNA - lymph node [nTPM]":"60.5","Tissue RNA - medulla oblongata [nTPM]":"39.2","Tissue RNA - midbrain [nTPM]":"37.3","Tissue RNA - ovary [nTPM]":"62.2","Tissue RNA - pancreas [nTPM]":"80.2","Tissue RNA - parathyroid gland [nTPM]":"85.7","Tissue RNA - pituitary gland [nTPM]":"66.3","Tissue RNA - placenta [nTPM]":"45.1","Tissue RNA - pons [nTPM]":"37.0","Tissue RNA - prostate [nTPM]":"53.6","Tissue RNA - rectum [nTPM]":"40.6","Tissue RNA - retina [nTPM]":"106.7","Tissue RNA - salivary gland [nTPM]":"60.6","Tissue RNA - seminal vesicle [nTPM]":"53.2","Tissue RNA - skeletal muscle [nTPM]":"219.7","Tissue RNA - skin 1 [nTPM]":"67.2","Tissue RNA - small intestine [nTPM]":"61.8","Tissue RNA - smooth muscle [nTPM]":"44.0","Tissue RNA - spinal cord [nTPM]":"32.6","Tissue RNA - spleen [nTPM]":"65.6","Tissue RNA - stomach 1 [nTPM]":"67.3","Tissue RNA - testis [nTPM]":"40.7","Tissue RNA - thalamus [nTPM]":"41.1","Tissue RNA - thymus [nTPM]":"67.5","Tissue RNA - thyroid gland [nTPM]":"77.9","Tissue RNA - tongue [nTPM]":"118.3","Tissue RNA - tonsil [nTPM]":"51.1","Tissue RNA - urinary bladder [nTPM]":"61.1","Tissue RNA - vagina [nTPM]":"49.8","Tissue RNA - white matter [nTPM]":"53.0","Cell RNA - A-431 [nTPM]":"54.2","Cell RNA - A549 [nTPM]":"62.5","Cell RNA - AF22 [nTPM]":"72.0","Cell RNA - AN3-CA [nTPM]":"64.8","Cell RNA - ASC diff [nTPM]":"86.3","Cell RNA - ASC TERT1 [nTPM]":"65.5","Cell RNA - BEWO [nTPM]":"63.7","Cell RNA - BJ [nTPM]":"62.7","Cell RNA - BJ hTERT+ [nTPM]":"81.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.2","Cell RNA - CACO-2 [nTPM]":"69.8","Cell RNA - CAPAN-2 [nTPM]":"89.6","Cell RNA - Daudi [nTPM]":"56.3","Cell RNA - EFO-21 [nTPM]":"112.1","Cell RNA - fHDF\/TERT166 [nTPM]":"67.2","Cell RNA - GAMG [nTPM]":"34.6","Cell RNA - HaCaT [nTPM]":"64.8","Cell RNA - HAP1 [nTPM]":"34.6","Cell RNA - HBEC3-KT [nTPM]":"57.4","Cell RNA - HBF TERT88 [nTPM]":"31.0","Cell RNA - HDLM-2 [nTPM]":"134.9","Cell RNA - HEK 293 [nTPM]":"69.0","Cell RNA - HEL [nTPM]":"63.4","Cell RNA - HeLa [nTPM]":"99.7","Cell RNA - Hep G2 [nTPM]":"54.1","Cell RNA - HHSteC [nTPM]":"69.3","Cell RNA - HL-60 [nTPM]":"52.9","Cell RNA - HMC-1 [nTPM]":"80.3","Cell RNA - HSkMC [nTPM]":"74.6","Cell RNA - hTCEpi [nTPM]":"58.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.2","Cell RNA - hTERT-HME1 [nTPM]":"60.8","Cell RNA - hTERT-RPE1 [nTPM]":"55.3","Cell RNA - HUVEC TERT2 [nTPM]":"73.5","Cell RNA - JURKAT [nTPM]":"73.1","Cell RNA - K-562 [nTPM]":"60.6","Cell RNA - Karpas-707 [nTPM]":"98.4","Cell RNA - LHCN-M2 [nTPM]":"46.0","Cell RNA - MCF7 [nTPM]":"50.0","Cell RNA - MOLT-4 [nTPM]":"71.7","Cell RNA - NB-4 [nTPM]":"54.5","Cell RNA - NTERA-2 [nTPM]":"52.7","Cell RNA - OE19 [nTPM]":"70.1","Cell RNA - PC-3 [nTPM]":"62.6","Cell RNA - REH [nTPM]":"69.2","Cell RNA - RH-30 [nTPM]":"41.8","Cell RNA - RPMI-8226 [nTPM]":"115.5","Cell RNA - RPTEC TERT1 [nTPM]":"57.7","Cell RNA - RT4 [nTPM]":"87.6","Cell RNA - SCLC-21H [nTPM]":"49.0","Cell RNA - SH-SY5Y [nTPM]":"47.3","Cell RNA - SiHa [nTPM]":"101.8","Cell RNA - SK-BR-3 [nTPM]":"113.1","Cell RNA - SK-MEL-30 [nTPM]":"68.2","Cell RNA - SuSa [nTPM]":"68.9","Cell RNA - T-47d [nTPM]":"104.9","Cell RNA - THP-1 [nTPM]":"82.0","Cell RNA - TIME [nTPM]":"95.1","Cell RNA - U-138 MG [nTPM]":"60.7","Cell RNA - U-2 OS [nTPM]":"31.5","Cell RNA - U-2197 [nTPM]":"38.6","Cell RNA - U-251 MG [nTPM]":"58.7","Cell RNA - U-266\/70 [nTPM]":"169.8","Cell RNA - U-266\/84 [nTPM]":"124.9","Cell RNA - U-698 [nTPM]":"94.3","Cell RNA - U-87 MG [nTPM]":"68.7","Cell RNA - U-937 [nTPM]":"49.6","Cell RNA - WM-115 [nTPM]":"51.2","Blood RNA - basophil [nTPM]":"32.9","Blood RNA - classical monocyte [nTPM]":"21.5","Blood RNA - eosinophil [nTPM]":"22.0","Blood RNA - gdT-cell [nTPM]":"31.5","Blood RNA - intermediate monocyte [nTPM]":"19.7","Blood RNA - MAIT T-cell [nTPM]":"29.6","Blood RNA - memory B-cell [nTPM]":"28.5","Blood RNA - memory CD4 T-cell [nTPM]":"27.0","Blood RNA - memory CD8 T-cell [nTPM]":"29.2","Blood RNA - myeloid DC [nTPM]":"17.5","Blood RNA - naive B-cell [nTPM]":"30.4","Blood RNA - naive CD4 T-cell [nTPM]":"29.4","Blood RNA - naive CD8 T-cell [nTPM]":"27.0","Blood RNA - neutrophil [nTPM]":"24.9","Blood RNA - NK-cell [nTPM]":"30.4","Blood RNA - non-classical monocyte [nTPM]":"28.4","Blood RNA - plasmacytoid DC [nTPM]":"22.0","Blood RNA - T-reg [nTPM]":"30.4","Blood RNA - total PBMC [nTPM]":"19.2","Brain RNA - amygdala [nTPM]":"35.3","Brain RNA - basal ganglia [nTPM]":"43.3","Brain RNA - cerebellum [nTPM]":"47.7","Brain RNA - cerebral cortex [nTPM]":"52.8","Brain RNA - hippocampal formation [nTPM]":"33.7","Brain RNA - hypothalamus [nTPM]":"41.8","Brain RNA - medulla oblongata [nTPM]":"39.2","Brain RNA - midbrain [nTPM]":"37.3","Brain RNA - pons [nTPM]":"37.0","Brain RNA - spinal cord [nTPM]":"32.6","Brain RNA - thalamus [nTPM]":"41.1","Brain RNA - white matter [nTPM]":"53.0","Single Cell Type RNA - Adipocytes [nTPM]":"21.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.9","Single Cell Type RNA - Astrocytes [nTPM]":"57.5","Single Cell Type RNA - B-cells [nTPM]":"35.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.7","Single Cell Type RNA - Bipolar cells [nTPM]":"44.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"54.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"30.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.9","Single Cell Type RNA - dendritic cells [nTPM]":"26.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"62.6","Single Cell Type RNA - Ductal cells [nTPM]":"23.9","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.9","Single Cell Type RNA - Endothelial cells [nTPM]":"26.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.1","Single Cell Type RNA - Erythroid cells [nTPM]":"48.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.0","Single Cell Type RNA - Fibroblasts [nTPM]":"28.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.4","Single Cell Type RNA - granulocytes [nTPM]":"34.1","Single Cell Type RNA - Granulosa cells [nTPM]":"21.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"77.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.8","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"49.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.2","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"29.8","Single Cell Type RNA - Langerhans cells [nTPM]":"18.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"28.0","Single Cell Type RNA - Macrophages [nTPM]":"24.2","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"27.6","Single Cell Type RNA - Muller glia cells [nTPM]":"38.1","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"58.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"93.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.2","Single Cell Type RNA - Paneth cells [nTPM]":"13.6","Single Cell Type RNA - Peritubular cells [nTPM]":"32.7","Single Cell Type RNA - Plasma cells [nTPM]":"45.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.6","Single Cell Type RNA - Spermatocytes [nTPM]":"28.0","Single Cell Type RNA - Spermatogonia [nTPM]":"20.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"44.3","Single Cell Type RNA - T-cells [nTPM]":"36.5","Single Cell Type RNA - Theca cells [nTPM]":"25.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.8","Single Cell Type RNA - Urothelial cells [nTPM]":"12.5"},{"Gene":"DCC","Gene synonym":["IGDCC1","NTN1R1"],"Ensembl":"ENSG00000187323","Gene description":"DCC netrin 1 receptor","Uniprot":["P43146"],"Chromosome":"18","Position":"52340197-53535903","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"6.9","testis":"7.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"205.7","Excitatory neurons":"439.7","Inhibitory neurons":"455.8","Late spermatids":"174.9","Oligodendrocyte precursor cells":"1305.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"AF22":"36.4","U-266\/70":"112.5","U-266\/84":"57.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055376","HPA069552"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"64000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA055376":"AB_2682798","HPA069552":"AB_2686151"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"36.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"15.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"11.4","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"112.5","Cell RNA - U-266\/84 [nTPM]":"57.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"6.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"205.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"439.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"455.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"174.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"54.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1305.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"58.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"5.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"DCDC2","Gene synonym":["DCDC2A","DFNB66","KIAA1154","NPHP19","RU2"],"Ensembl":"ENSG00000146038","Gene description":"Doublecortin domain containing 2","Uniprot":["Q9UHG0"],"Chromosome":"6","Position":"24171755-24358059","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Neurogenesis"],"Molecular function":null,"Disease involvement":["Ciliopathy","Deafness","Disease variant","Nephronophthisis","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"15.1","kidney":"23.2","pancreas":"26.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"62.9","Collecting duct cells":"79.1","Distal tubular cells":"56.7","Ductal cells":"135.9","Endometrial ciliated cells":"160.3","Glandular and luminal cells":"102.4","Proximal tubular cells":"54.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"71.8","EFO-21":"48.3","Hep G2":"82.3","RPTEC TERT1":"254.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031582","HPA031583","HPA031584"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules","Mitotic spindle","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Microtubules","Mitotic spindle","Centriolar satellite"],"Antibody RRID":{"HPA031582":"AB_10600901","HPA031583":"AB_2673944","HPA031584":"AB_2673945"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"15.1","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"23.2","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"26.2","Tissue RNA - parathyroid gland [nTPM]":"8.2","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"1.8","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"8.2","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"8.8","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"71.8","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"48.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"8.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"82.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.7","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"10.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"254.5","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"12.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.4","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"62.9","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"56.7","Single Cell Type RNA - Ductal cells [nTPM]":"135.9","Single Cell Type RNA - Early spermatids [nTPM]":"40.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"160.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"102.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"14.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.9","Single Cell Type RNA - Paneth cells [nTPM]":"4.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"54.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"32.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"5.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"DCN","Gene synonym":["DSPG2","SLRR1B"],"Ensembl":"ENSG00000011465","Gene description":"Decorin","Uniprot":["P07585"],"Chromosome":"12","Position":"91140484-91183217","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Corneal dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"1218.7","Fibroblasts":"7960.2","Leydig cells":"6281.9","Peritubular cells":"1856.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"24.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"granulocytes":"24.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"3291.1","ASC TERT1":"2371.6","BJ hTERT+":"2546.6","HSkMC":"2289.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"spinal cord":"544.7"},"Antibody":["HPA003315","CAB017118","HPA064736","CAB068930"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB017118":null,"CAB068930":"AB_425394","HPA003315":"AB_1078639","HPA064736":"AB_2685340"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.46e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-3"},"Tissue RNA - adipose tissue [nTPM]":"1522.3","Tissue RNA - adrenal gland [nTPM]":"1171.7","Tissue RNA - amygdala [nTPM]":"60.6","Tissue RNA - appendix [nTPM]":"272.0","Tissue RNA - basal ganglia [nTPM]":"80.0","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"2342.2","Tissue RNA - cerebellum [nTPM]":"63.5","Tissue RNA - cerebral cortex [nTPM]":"119.2","Tissue RNA - cervix [nTPM]":"1493.0","Tissue RNA - choroid plexus [nTPM]":"111.6","Tissue RNA - colon [nTPM]":"549.9","Tissue RNA - duodenum [nTPM]":"163.5","Tissue RNA - endometrium 1 [nTPM]":"1308.5","Tissue RNA - epididymis [nTPM]":"1302.0","Tissue RNA - esophagus [nTPM]":"932.8","Tissue RNA - fallopian tube [nTPM]":"1213.4","Tissue RNA - gallbladder [nTPM]":"1802.7","Tissue RNA - heart muscle [nTPM]":"2108.9","Tissue RNA - hippocampal formation [nTPM]":"66.8","Tissue RNA - hypothalamus [nTPM]":"60.3","Tissue RNA - kidney [nTPM]":"394.8","Tissue RNA - liver [nTPM]":"459.6","Tissue RNA - lung [nTPM]":"955.8","Tissue RNA - lymph node [nTPM]":"130.4","Tissue RNA - medulla oblongata [nTPM]":"68.9","Tissue RNA - midbrain [nTPM]":"60.9","Tissue RNA - ovary [nTPM]":"2681.4","Tissue RNA - pancreas [nTPM]":"257.9","Tissue RNA - parathyroid gland [nTPM]":"80.2","Tissue RNA - pituitary gland [nTPM]":"112.0","Tissue RNA - placenta [nTPM]":"1534.8","Tissue RNA - pons [nTPM]":"75.7","Tissue RNA - prostate [nTPM]":"451.6","Tissue RNA - rectum [nTPM]":"493.0","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"362.5","Tissue RNA - seminal vesicle [nTPM]":"462.3","Tissue RNA - skeletal muscle [nTPM]":"469.0","Tissue RNA - skin 1 [nTPM]":"713.4","Tissue RNA - small intestine [nTPM]":"336.6","Tissue RNA - smooth muscle [nTPM]":"1027.8","Tissue RNA - spinal cord [nTPM]":"70.2","Tissue RNA - spleen [nTPM]":"20.0","Tissue RNA - stomach 1 [nTPM]":"434.5","Tissue RNA - testis [nTPM]":"279.6","Tissue RNA - thalamus [nTPM]":"72.8","Tissue RNA - thymus [nTPM]":"183.0","Tissue RNA - thyroid gland [nTPM]":"479.3","Tissue RNA - tongue [nTPM]":"1328.3","Tissue RNA - tonsil [nTPM]":"293.6","Tissue RNA - urinary bladder [nTPM]":"1895.5","Tissue RNA - vagina [nTPM]":"783.7","Tissue RNA - white matter [nTPM]":"57.9","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"4.4","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"3291.1","Cell RNA - ASC TERT1 [nTPM]":"2371.6","Cell RNA - BEWO [nTPM]":"6.2","Cell RNA - BJ [nTPM]":"608.7","Cell RNA - BJ hTERT+ [nTPM]":"2546.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.5","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"523.5","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"2.1","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"1.9","Cell RNA - HBF TERT88 [nTPM]":"4.9","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"20.4","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"717.4","Cell RNA - HL-60 [nTPM]":"1.3","Cell RNA - HMC-1 [nTPM]":"1.4","Cell RNA - HSkMC [nTPM]":"2289.4","Cell RNA - hTCEpi [nTPM]":"8.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"78.3","Cell RNA - hTERT-HME1 [nTPM]":"38.5","Cell RNA - hTERT-RPE1 [nTPM]":"12.1","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"63.0","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"10.8","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"1.6","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"2.3","Cell RNA - RPMI-8226 [nTPM]":"2.8","Cell RNA - RPTEC TERT1 [nTPM]":"3.4","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"10.3","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"1.8","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"132.3","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"497.5","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"3.3","Cell RNA - U-266\/84 [nTPM]":"3.1","Cell RNA - U-698 [nTPM]":"2.0","Cell RNA - U-87 MG [nTPM]":"8.0","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"24.5","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"60.6","Brain RNA - basal ganglia [nTPM]":"80.0","Brain RNA - cerebellum [nTPM]":"63.5","Brain RNA - cerebral cortex [nTPM]":"119.2","Brain RNA - hippocampal formation [nTPM]":"66.8","Brain RNA - hypothalamus [nTPM]":"60.3","Brain RNA - medulla oblongata [nTPM]":"68.9","Brain RNA - midbrain [nTPM]":"60.9","Brain RNA - pons [nTPM]":"75.7","Brain RNA - spinal cord [nTPM]":"70.2","Brain RNA - thalamus [nTPM]":"72.8","Brain RNA - white matter [nTPM]":"57.9","Single Cell Type RNA - Adipocytes [nTPM]":"351.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"44.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"609.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"264.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"154.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"11.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - dendritic cells [nTPM]":"12.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"25.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1218.7","Single Cell Type RNA - Endothelial cells [nTPM]":"158.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.0","Single Cell Type RNA - Fibroblasts [nTPM]":"7960.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"54.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.0","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"214.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"58.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"962.7","Single Cell Type RNA - Late spermatids [nTPM]":"103.0","Single Cell Type RNA - Leydig cells [nTPM]":"6281.9","Single Cell Type RNA - Macrophages [nTPM]":"52.5","Single Cell Type RNA - Melanocytes [nTPM]":"606.5","Single Cell Type RNA - Microglial cells [nTPM]":"122.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"1856.9","Single Cell Type RNA - Plasma cells [nTPM]":"23.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"210.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"236.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"408.2","Single Cell Type RNA - Spermatocytes [nTPM]":"13.4","Single Cell Type RNA - Spermatogonia [nTPM]":"9.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"482.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"63.9","Single Cell Type RNA - T-cells [nTPM]":"72.3","Single Cell Type RNA - Theca cells [nTPM]":"70.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"DCTN1","Gene synonym":[],"Ensembl":"ENSG00000204843","Gene description":"Dynactin subunit 1","Uniprot":["Q14203"],"Chromosome":"2","Position":"74361154-74392087","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","Transport"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Cancer-related genes","Neurodegeneration","Neuropathy","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009108","HPA034635","HPA071875"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules","Cytokinetic bridge","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"250000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Microtubules"],"Subcellular additional location":["Cytokinetic bridge","Mitotic spindle"],"Antibody RRID":{"CAB009108":"AB_2090601","HPA034635":"AB_2674256","HPA071875":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.34e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Tissue RNA - adipose tissue [nTPM]":"43.3","Tissue RNA - adrenal gland [nTPM]":"40.0","Tissue RNA - amygdala [nTPM]":"90.5","Tissue RNA - appendix [nTPM]":"27.0","Tissue RNA - basal ganglia [nTPM]":"94.7","Tissue RNA - bone marrow [nTPM]":"23.7","Tissue RNA - breast [nTPM]":"37.4","Tissue RNA - cerebellum [nTPM]":"76.4","Tissue RNA - cerebral cortex [nTPM]":"113.2","Tissue RNA - cervix [nTPM]":"44.3","Tissue RNA - choroid plexus [nTPM]":"20.8","Tissue RNA - colon [nTPM]":"51.3","Tissue RNA - duodenum [nTPM]":"22.2","Tissue RNA - endometrium 1 [nTPM]":"51.4","Tissue RNA - epididymis [nTPM]":"17.0","Tissue RNA - esophagus [nTPM]":"42.6","Tissue RNA - fallopian tube [nTPM]":"38.7","Tissue RNA - gallbladder [nTPM]":"28.2","Tissue RNA - heart muscle [nTPM]":"82.6","Tissue RNA - hippocampal formation [nTPM]":"99.9","Tissue RNA - hypothalamus [nTPM]":"80.1","Tissue RNA - kidney [nTPM]":"27.6","Tissue RNA - liver [nTPM]":"18.2","Tissue RNA - lung [nTPM]":"36.0","Tissue RNA - lymph node [nTPM]":"22.8","Tissue RNA - medulla oblongata [nTPM]":"110.9","Tissue RNA - midbrain [nTPM]":"85.1","Tissue RNA - ovary [nTPM]":"39.2","Tissue RNA - pancreas [nTPM]":"28.6","Tissue RNA - parathyroid gland [nTPM]":"118.0","Tissue RNA - pituitary gland [nTPM]":"61.2","Tissue RNA - placenta [nTPM]":"32.6","Tissue RNA - pons [nTPM]":"112.6","Tissue RNA - prostate [nTPM]":"30.0","Tissue RNA - rectum [nTPM]":"25.5","Tissue RNA - retina [nTPM]":"43.5","Tissue RNA - salivary gland [nTPM]":"56.3","Tissue RNA - seminal vesicle [nTPM]":"38.0","Tissue RNA - skeletal muscle [nTPM]":"87.6","Tissue RNA - skin 1 [nTPM]":"44.2","Tissue RNA - small intestine [nTPM]":"32.2","Tissue RNA - smooth muscle [nTPM]":"49.9","Tissue RNA - spinal cord [nTPM]":"76.0","Tissue RNA - spleen [nTPM]":"26.5","Tissue RNA - stomach 1 [nTPM]":"39.5","Tissue RNA - testis [nTPM]":"51.3","Tissue RNA - thalamus [nTPM]":"101.9","Tissue RNA - thymus [nTPM]":"34.7","Tissue RNA - thyroid gland [nTPM]":"31.3","Tissue RNA - tongue [nTPM]":"63.4","Tissue RNA - tonsil [nTPM]":"24.6","Tissue RNA - urinary bladder [nTPM]":"47.6","Tissue RNA - vagina [nTPM]":"39.0","Tissue RNA - white matter [nTPM]":"116.2","Cell RNA - A-431 [nTPM]":"65.0","Cell RNA - A549 [nTPM]":"74.7","Cell RNA - AF22 [nTPM]":"68.4","Cell RNA - AN3-CA [nTPM]":"71.9","Cell RNA - ASC diff [nTPM]":"122.5","Cell RNA - ASC TERT1 [nTPM]":"90.7","Cell RNA - BEWO [nTPM]":"55.2","Cell RNA - BJ [nTPM]":"102.0","Cell RNA - BJ hTERT+ [nTPM]":"105.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"127.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.9","Cell RNA - CACO-2 [nTPM]":"99.9","Cell RNA - CAPAN-2 [nTPM]":"48.6","Cell RNA - Daudi [nTPM]":"88.8","Cell RNA - EFO-21 [nTPM]":"40.8","Cell RNA - fHDF\/TERT166 [nTPM]":"213.0","Cell RNA - GAMG [nTPM]":"70.1","Cell RNA - HaCaT [nTPM]":"63.5","Cell RNA - HAP1 [nTPM]":"84.3","Cell RNA - HBEC3-KT [nTPM]":"129.5","Cell RNA - HBF TERT88 [nTPM]":"96.1","Cell RNA - HDLM-2 [nTPM]":"111.2","Cell RNA - HEK 293 [nTPM]":"85.0","Cell RNA - HEL [nTPM]":"92.5","Cell RNA - HeLa [nTPM]":"55.6","Cell RNA - Hep G2 [nTPM]":"84.7","Cell RNA - HHSteC [nTPM]":"94.4","Cell RNA - HL-60 [nTPM]":"50.7","Cell RNA - HMC-1 [nTPM]":"109.3","Cell RNA - HSkMC [nTPM]":"109.6","Cell RNA - hTCEpi [nTPM]":"62.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"138.3","Cell RNA - hTERT-HME1 [nTPM]":"82.3","Cell RNA - hTERT-RPE1 [nTPM]":"86.9","Cell RNA - HUVEC TERT2 [nTPM]":"110.3","Cell RNA - JURKAT [nTPM]":"79.4","Cell RNA - K-562 [nTPM]":"40.3","Cell RNA - Karpas-707 [nTPM]":"61.4","Cell RNA - LHCN-M2 [nTPM]":"97.3","Cell RNA - MCF7 [nTPM]":"55.6","Cell RNA - MOLT-4 [nTPM]":"92.8","Cell RNA - NB-4 [nTPM]":"52.5","Cell RNA - NTERA-2 [nTPM]":"74.0","Cell RNA - OE19 [nTPM]":"78.6","Cell RNA - PC-3 [nTPM]":"78.3","Cell RNA - REH [nTPM]":"82.3","Cell RNA - RH-30 [nTPM]":"120.1","Cell RNA - RPMI-8226 [nTPM]":"63.8","Cell RNA - RPTEC TERT1 [nTPM]":"70.2","Cell RNA - RT4 [nTPM]":"39.6","Cell RNA - SCLC-21H [nTPM]":"83.3","Cell RNA - SH-SY5Y [nTPM]":"74.1","Cell RNA - SiHa [nTPM]":"57.1","Cell RNA - SK-BR-3 [nTPM]":"67.7","Cell RNA - SK-MEL-30 [nTPM]":"60.6","Cell RNA - SuSa [nTPM]":"59.0","Cell RNA - T-47d [nTPM]":"43.5","Cell RNA - THP-1 [nTPM]":"36.5","Cell RNA - TIME [nTPM]":"84.3","Cell RNA - U-138 MG [nTPM]":"115.0","Cell RNA - U-2 OS [nTPM]":"82.7","Cell RNA - U-2197 [nTPM]":"50.0","Cell RNA - U-251 MG [nTPM]":"77.2","Cell RNA - U-266\/70 [nTPM]":"37.8","Cell RNA - U-266\/84 [nTPM]":"32.7","Cell RNA - U-698 [nTPM]":"78.9","Cell RNA - U-87 MG [nTPM]":"107.6","Cell RNA - U-937 [nTPM]":"81.4","Cell RNA - WM-115 [nTPM]":"82.5","Blood RNA - basophil [nTPM]":"8.3","Blood RNA - classical monocyte [nTPM]":"11.3","Blood RNA - eosinophil [nTPM]":"12.7","Blood RNA - gdT-cell [nTPM]":"14.4","Blood RNA - intermediate monocyte [nTPM]":"13.0","Blood RNA - MAIT T-cell [nTPM]":"11.7","Blood RNA - memory B-cell [nTPM]":"10.1","Blood RNA - memory CD4 T-cell [nTPM]":"8.2","Blood RNA - memory CD8 T-cell [nTPM]":"10.8","Blood RNA - myeloid DC [nTPM]":"11.2","Blood RNA - naive B-cell [nTPM]":"6.8","Blood RNA - naive CD4 T-cell [nTPM]":"5.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.3","Blood RNA - neutrophil [nTPM]":"9.2","Blood RNA - NK-cell [nTPM]":"9.2","Blood RNA - non-classical monocyte [nTPM]":"15.6","Blood RNA - plasmacytoid DC [nTPM]":"8.8","Blood RNA - T-reg [nTPM]":"7.7","Blood RNA - total PBMC [nTPM]":"16.5","Brain RNA - amygdala [nTPM]":"90.5","Brain RNA - basal ganglia [nTPM]":"94.7","Brain RNA - cerebellum [nTPM]":"76.4","Brain RNA - cerebral cortex [nTPM]":"113.2","Brain RNA - hippocampal formation [nTPM]":"99.9","Brain RNA - hypothalamus [nTPM]":"80.1","Brain RNA - medulla oblongata [nTPM]":"110.9","Brain RNA - midbrain [nTPM]":"85.1","Brain RNA - pons [nTPM]":"112.6","Brain RNA - spinal cord [nTPM]":"76.0","Brain RNA - thalamus [nTPM]":"101.9","Brain RNA - white matter [nTPM]":"116.2","Single Cell Type RNA - Adipocytes [nTPM]":"28.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.4","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"23.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"27.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"56.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"20.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.8","Single Cell Type RNA - dendritic cells [nTPM]":"19.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"22.5","Single Cell Type RNA - Early spermatids [nTPM]":"7.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.8","Single Cell Type RNA - Endothelial cells [nTPM]":"26.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.7","Single Cell Type RNA - Erythroid cells [nTPM]":"27.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.1","Single Cell Type RNA - Fibroblasts [nTPM]":"25.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.8","Single Cell Type RNA - granulocytes [nTPM]":"29.2","Single Cell Type RNA - Granulosa cells [nTPM]":"30.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"19.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.8","Single Cell Type RNA - Horizontal cells [nTPM]":"90.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.8","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"11.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.3","Single Cell Type RNA - Leydig cells [nTPM]":"44.7","Single Cell Type RNA - Macrophages [nTPM]":"21.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"27.3","Single Cell Type RNA - Muller glia cells [nTPM]":"14.9","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.6","Single Cell Type RNA - Paneth cells [nTPM]":"33.6","Single Cell Type RNA - Peritubular cells [nTPM]":"51.9","Single Cell Type RNA - Plasma cells [nTPM]":"24.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"45.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.0","Single Cell Type RNA - Spermatocytes [nTPM]":"40.6","Single Cell Type RNA - Spermatogonia [nTPM]":"38.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - T-cells [nTPM]":"20.0","Single Cell Type RNA - Theca cells [nTPM]":"33.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.9","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"DDC","Gene synonym":["AADC"],"Ensembl":"ENSG00000132437","Gene description":"Dopa decarboxylase","Uniprot":["P20711"],"Chromosome":"7","Position":"50458436-50565405","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Catecholamine biosynthesis"],"Molecular function":["Decarboxylase","Lyase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"165.8","kidney":"314.9","retina":"175.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Enteroendocrine cells":"410.3","Proximal enterocytes":"391.5","Proximal tubular cells":"429.5","Rod photoreceptor cells":"498.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"23.5","liver cancer":"13.4","pancreatic cancer":"6.4","renal cancer":"18.7","stomach cancer":"9.9"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"midbrain":"86.3","pons":"29.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"CACO-2":"54.5","Hep G2":"49.3","OE19":"83.6","SCLC-21H":"130.9","SH-SY5Y":"135.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"74.5","pons":"29.4"},"Antibody":["HPA017742"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA017742":"AB_1847832"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"48.9","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"2.3","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"36.5","Tissue RNA - duodenum [nTPM]":"154.8","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"9.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"314.9","Tissue RNA - liver [nTPM]":"54.6","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"86.3","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"15.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"29.4","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"37.5","Tissue RNA - retina [nTPM]":"175.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"165.8","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"18.1","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"54.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"49.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"11.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"83.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"1.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"130.9","Cell RNA - SH-SY5Y [nTPM]":"135.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"4.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"86.3","Brain RNA - pons [nTPM]":"29.4","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"89.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"410.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"67.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"67.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"45.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"31.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"391.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"429.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"498.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"88.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"DDHD1","Gene synonym":["KIAA1705","PA-PLA1","SPG28"],"Ensembl":"ENSG00000100523","Gene description":"DDHD domain containing 1","Uniprot":["Q8NEL9"],"Chromosome":"14","Position":"53036745-53153323","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"30.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"280.9","Excitatory neurons":"140.5","Late spermatids":"146.3","Oligodendrocytes":"177.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049870"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049870":"AB_2680925"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"6.6","Tissue RNA - bone marrow [nTPM]":"8.7","Tissue RNA - breast [nTPM]":"3.9","Tissue RNA - cerebellum [nTPM]":"9.7","Tissue RNA - cerebral cortex [nTPM]":"10.1","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"3.8","Tissue RNA - duodenum [nTPM]":"2.5","Tissue RNA - endometrium 1 [nTPM]":"5.0","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"2.5","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"10.0","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"4.4","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"7.5","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"3.7","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"16.7","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"3.3","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"3.8","Tissue RNA - testis [nTPM]":"30.7","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"5.3","Tissue RNA - tonsil [nTPM]":"8.5","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"10.2","Cell RNA - AF22 [nTPM]":"32.5","Cell RNA - AN3-CA [nTPM]":"12.7","Cell RNA - ASC diff [nTPM]":"14.0","Cell RNA - ASC TERT1 [nTPM]":"12.7","Cell RNA - BEWO [nTPM]":"6.7","Cell RNA - BJ [nTPM]":"13.0","Cell RNA - BJ hTERT+ [nTPM]":"9.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.3","Cell RNA - CACO-2 [nTPM]":"2.4","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"23.3","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"9.1","Cell RNA - GAMG [nTPM]":"8.7","Cell RNA - HaCaT [nTPM]":"3.7","Cell RNA - HAP1 [nTPM]":"15.8","Cell RNA - HBEC3-KT [nTPM]":"3.6","Cell RNA - HBF TERT88 [nTPM]":"11.3","Cell RNA - HDLM-2 [nTPM]":"12.8","Cell RNA - HEK 293 [nTPM]":"7.0","Cell RNA - HEL [nTPM]":"3.0","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"4.7","Cell RNA - HHSteC [nTPM]":"12.1","Cell RNA - HL-60 [nTPM]":"10.6","Cell RNA - HMC-1 [nTPM]":"10.3","Cell RNA - HSkMC [nTPM]":"6.9","Cell RNA - hTCEpi [nTPM]":"4.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"8.4","Cell RNA - hTERT-RPE1 [nTPM]":"6.7","Cell RNA - HUVEC TERT2 [nTPM]":"7.1","Cell RNA - JURKAT [nTPM]":"7.9","Cell RNA - K-562 [nTPM]":"5.9","Cell RNA - Karpas-707 [nTPM]":"19.6","Cell RNA - LHCN-M2 [nTPM]":"11.0","Cell RNA - MCF7 [nTPM]":"9.2","Cell RNA - MOLT-4 [nTPM]":"12.6","Cell RNA - NB-4 [nTPM]":"5.4","Cell RNA - NTERA-2 [nTPM]":"6.7","Cell RNA - OE19 [nTPM]":"5.6","Cell RNA - PC-3 [nTPM]":"8.4","Cell RNA - REH [nTPM]":"9.6","Cell RNA - RH-30 [nTPM]":"34.0","Cell RNA - RPMI-8226 [nTPM]":"4.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"11.3","Cell RNA - SCLC-21H [nTPM]":"14.5","Cell RNA - SH-SY5Y [nTPM]":"9.3","Cell RNA - SiHa [nTPM]":"15.2","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"4.4","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"5.9","Cell RNA - THP-1 [nTPM]":"6.9","Cell RNA - TIME [nTPM]":"10.5","Cell RNA - U-138 MG [nTPM]":"8.9","Cell RNA - U-2 OS [nTPM]":"13.9","Cell RNA - U-2197 [nTPM]":"13.4","Cell RNA - U-251 MG [nTPM]":"9.6","Cell RNA - U-266\/70 [nTPM]":"9.1","Cell RNA - U-266\/84 [nTPM]":"6.3","Cell RNA - U-698 [nTPM]":"15.3","Cell RNA - U-87 MG [nTPM]":"4.7","Cell RNA - U-937 [nTPM]":"9.6","Cell RNA - WM-115 [nTPM]":"5.0","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"4.6","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"4.4","Blood RNA - memory B-cell [nTPM]":"3.2","Blood RNA - memory CD4 T-cell [nTPM]":"3.7","Blood RNA - memory CD8 T-cell [nTPM]":"5.1","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"3.2","Blood RNA - naive CD8 T-cell [nTPM]":"3.9","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"4.6","Blood RNA - non-classical monocyte [nTPM]":"3.7","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"6.6","Brain RNA - cerebellum [nTPM]":"9.7","Brain RNA - cerebral cortex [nTPM]":"10.1","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"12.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.4","Single Cell Type RNA - Astrocytes [nTPM]":"69.9","Single Cell Type RNA - B-cells [nTPM]":"40.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"64.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"3.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"87.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.6","Single Cell Type RNA - dendritic cells [nTPM]":"46.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.8","Single Cell Type RNA - Early spermatids [nTPM]":"280.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.7","Single Cell Type RNA - Endothelial cells [nTPM]":"19.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"27.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"140.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"25.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.3","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"20.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"5.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.2","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"120.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"13.3","Single Cell Type RNA - Late spermatids [nTPM]":"146.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"31.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"22.1","Single Cell Type RNA - Muller glia cells [nTPM]":"19.1","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"104.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"177.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.4","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"42.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.8","Single Cell Type RNA - Spermatocytes [nTPM]":"57.4","Single Cell Type RNA - Spermatogonia [nTPM]":"46.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - T-cells [nTPM]":"42.4","Single Cell Type RNA - Theca cells [nTPM]":"24.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.6","Single Cell Type RNA - Urothelial cells [nTPM]":"5.9"},{"Gene":"DDHD2","Gene synonym":["KIAA0725","SAMWD1","SPG54"],"Ensembl":"ENSG00000085788","Gene description":"DDHD domain containing 2","Uniprot":["O94830"],"Chromosome":"8","Position":"38225218-38275558","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015202","HPA023143","HPA023147"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"CAB015202":null,"HPA023143":"AB_1847534","HPA023147":"AB_1847535"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.72e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.9","Tissue RNA - adrenal gland [nTPM]":"18.1","Tissue RNA - amygdala [nTPM]":"27.3","Tissue RNA - appendix [nTPM]":"14.4","Tissue RNA - basal ganglia [nTPM]":"32.1","Tissue RNA - bone marrow [nTPM]":"14.9","Tissue RNA - breast [nTPM]":"19.4","Tissue RNA - cerebellum [nTPM]":"33.8","Tissue RNA - cerebral cortex [nTPM]":"39.7","Tissue RNA - cervix [nTPM]":"22.0","Tissue RNA - choroid plexus [nTPM]":"23.5","Tissue RNA - colon [nTPM]":"20.1","Tissue RNA - duodenum [nTPM]":"19.6","Tissue RNA - endometrium 1 [nTPM]":"20.9","Tissue RNA - epididymis [nTPM]":"23.3","Tissue RNA - esophagus [nTPM]":"20.9","Tissue RNA - fallopian tube [nTPM]":"19.1","Tissue RNA - gallbladder [nTPM]":"17.5","Tissue RNA - heart muscle [nTPM]":"27.7","Tissue RNA - hippocampal formation [nTPM]":"30.1","Tissue RNA - hypothalamus [nTPM]":"29.3","Tissue RNA - kidney [nTPM]":"21.6","Tissue RNA - liver [nTPM]":"12.1","Tissue RNA - lung [nTPM]":"16.9","Tissue RNA - lymph node [nTPM]":"19.8","Tissue RNA - medulla oblongata [nTPM]":"32.1","Tissue RNA - midbrain [nTPM]":"27.7","Tissue RNA - ovary [nTPM]":"28.9","Tissue RNA - pancreas [nTPM]":"22.2","Tissue RNA - parathyroid gland [nTPM]":"21.1","Tissue RNA - pituitary gland [nTPM]":"18.3","Tissue RNA - placenta [nTPM]":"15.2","Tissue RNA - pons [nTPM]":"35.1","Tissue RNA - prostate [nTPM]":"22.6","Tissue RNA - rectum [nTPM]":"16.7","Tissue RNA - retina [nTPM]":"31.7","Tissue RNA - salivary gland [nTPM]":"18.3","Tissue RNA - seminal vesicle [nTPM]":"29.3","Tissue RNA - skeletal muscle [nTPM]":"32.0","Tissue RNA - skin 1 [nTPM]":"16.8","Tissue RNA - small intestine [nTPM]":"22.2","Tissue RNA - smooth muscle [nTPM]":"18.2","Tissue RNA - spinal cord [nTPM]":"30.7","Tissue RNA - spleen [nTPM]":"17.2","Tissue RNA - stomach 1 [nTPM]":"15.0","Tissue RNA - testis [nTPM]":"22.7","Tissue RNA - thalamus [nTPM]":"32.4","Tissue RNA - thymus [nTPM]":"19.5","Tissue RNA - thyroid gland [nTPM]":"18.7","Tissue RNA - tongue [nTPM]":"35.8","Tissue RNA - tonsil [nTPM]":"22.3","Tissue RNA - urinary bladder [nTPM]":"17.6","Tissue RNA - vagina [nTPM]":"17.7","Tissue RNA - white matter [nTPM]":"38.8","Cell RNA - A-431 [nTPM]":"57.7","Cell RNA - A549 [nTPM]":"26.1","Cell RNA - AF22 [nTPM]":"58.3","Cell RNA - AN3-CA [nTPM]":"28.3","Cell RNA - ASC diff [nTPM]":"21.8","Cell RNA - ASC TERT1 [nTPM]":"30.6","Cell RNA - BEWO [nTPM]":"18.4","Cell RNA - BJ [nTPM]":"18.1","Cell RNA - BJ hTERT+ [nTPM]":"33.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.4","Cell RNA - CACO-2 [nTPM]":"30.8","Cell RNA - CAPAN-2 [nTPM]":"22.6","Cell RNA - Daudi [nTPM]":"22.8","Cell RNA - EFO-21 [nTPM]":"24.1","Cell RNA - fHDF\/TERT166 [nTPM]":"32.8","Cell RNA - GAMG [nTPM]":"26.3","Cell RNA - HaCaT [nTPM]":"22.7","Cell RNA - HAP1 [nTPM]":"33.9","Cell RNA - HBEC3-KT [nTPM]":"34.1","Cell RNA - HBF TERT88 [nTPM]":"64.9","Cell RNA - HDLM-2 [nTPM]":"19.8","Cell RNA - HEK 293 [nTPM]":"22.6","Cell RNA - HEL [nTPM]":"83.0","Cell RNA - HeLa [nTPM]":"36.0","Cell RNA - Hep G2 [nTPM]":"29.9","Cell RNA - HHSteC [nTPM]":"19.6","Cell RNA - HL-60 [nTPM]":"9.6","Cell RNA - HMC-1 [nTPM]":"12.8","Cell RNA - HSkMC [nTPM]":"16.0","Cell RNA - hTCEpi [nTPM]":"26.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.4","Cell RNA - hTERT-HME1 [nTPM]":"26.8","Cell RNA - hTERT-RPE1 [nTPM]":"27.0","Cell RNA - HUVEC TERT2 [nTPM]":"51.5","Cell RNA - JURKAT [nTPM]":"31.2","Cell RNA - K-562 [nTPM]":"59.6","Cell RNA - Karpas-707 [nTPM]":"24.5","Cell RNA - LHCN-M2 [nTPM]":"27.3","Cell RNA - MCF7 [nTPM]":"12.3","Cell RNA - MOLT-4 [nTPM]":"66.6","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"13.2","Cell RNA - OE19 [nTPM]":"9.5","Cell RNA - PC-3 [nTPM]":"15.1","Cell RNA - REH [nTPM]":"34.0","Cell RNA - RH-30 [nTPM]":"50.1","Cell RNA - RPMI-8226 [nTPM]":"16.5","Cell RNA - RPTEC TERT1 [nTPM]":"22.5","Cell RNA - RT4 [nTPM]":"34.8","Cell RNA - SCLC-21H [nTPM]":"21.2","Cell RNA - SH-SY5Y [nTPM]":"32.0","Cell RNA - SiHa [nTPM]":"44.4","Cell RNA - SK-BR-3 [nTPM]":"21.9","Cell RNA - SK-MEL-30 [nTPM]":"22.2","Cell RNA - SuSa [nTPM]":"18.2","Cell RNA - T-47d [nTPM]":"26.3","Cell RNA - THP-1 [nTPM]":"26.1","Cell RNA - TIME [nTPM]":"46.6","Cell RNA - U-138 MG [nTPM]":"24.8","Cell RNA - U-2 OS [nTPM]":"31.1","Cell RNA - U-2197 [nTPM]":"24.3","Cell RNA - U-251 MG [nTPM]":"28.4","Cell RNA - U-266\/70 [nTPM]":"25.7","Cell RNA - U-266\/84 [nTPM]":"25.8","Cell RNA - U-698 [nTPM]":"54.0","Cell RNA - U-87 MG [nTPM]":"39.5","Cell RNA - U-937 [nTPM]":"18.4","Cell RNA - WM-115 [nTPM]":"35.3","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"4.7","Blood RNA - gdT-cell [nTPM]":"10.6","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"11.8","Blood RNA - memory B-cell [nTPM]":"9.8","Blood RNA - memory CD4 T-cell [nTPM]":"9.6","Blood RNA - memory CD8 T-cell [nTPM]":"11.9","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"15.2","Blood RNA - naive CD4 T-cell [nTPM]":"10.2","Blood RNA - naive CD8 T-cell [nTPM]":"7.5","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"16.5","Blood RNA - non-classical monocyte [nTPM]":"3.5","Blood RNA - plasmacytoid DC [nTPM]":"3.8","Blood RNA - T-reg [nTPM]":"15.6","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"27.3","Brain RNA - basal ganglia [nTPM]":"32.1","Brain RNA - cerebellum [nTPM]":"33.8","Brain RNA - cerebral cortex [nTPM]":"39.7","Brain RNA - hippocampal formation [nTPM]":"30.1","Brain RNA - hypothalamus [nTPM]":"29.3","Brain RNA - medulla oblongata [nTPM]":"32.1","Brain RNA - midbrain [nTPM]":"27.7","Brain RNA - pons [nTPM]":"35.1","Brain RNA - spinal cord [nTPM]":"30.7","Brain RNA - thalamus [nTPM]":"32.4","Brain RNA - white matter [nTPM]":"38.8","Single Cell Type RNA - Adipocytes [nTPM]":"15.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.0","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"17.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"27.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"8.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.1","Single Cell Type RNA - dendritic cells [nTPM]":"16.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"11.6","Single Cell Type RNA - Early spermatids [nTPM]":"4.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.4","Single Cell Type RNA - Endothelial cells [nTPM]":"13.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.7","Single Cell Type RNA - Erythroid cells [nTPM]":"25.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.5","Single Cell Type RNA - Fibroblasts [nTPM]":"13.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.4","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"22.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"5.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.4","Single Cell Type RNA - Horizontal cells [nTPM]":"53.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"51.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.3","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.4","Single Cell Type RNA - Langerhans cells [nTPM]":"11.2","Single Cell Type RNA - Late spermatids [nTPM]":"10.8","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"13.0","Single Cell Type RNA - Muller glia cells [nTPM]":"19.9","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.2","Single Cell Type RNA - Paneth cells [nTPM]":"6.2","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"24.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.6","Single Cell Type RNA - Spermatocytes [nTPM]":"30.9","Single Cell Type RNA - Spermatogonia [nTPM]":"35.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - T-cells [nTPM]":"17.9","Single Cell Type RNA - Theca cells [nTPM]":"13.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.9","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"DENND5A","Gene synonym":["FLJ22354","FLJ33829","FLJ43455","KIAA1091","RAB6IP1"],"Ensembl":"ENSG00000184014","Gene description":"DENN domain containing 5A","Uniprot":["Q6IQ26"],"Chromosome":"11","Position":"9138825-9265959","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"136.2","Oligodendrocytes":"287.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052923","HPA055009"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA052923":"AB_2681989","HPA055009":"AB_2682669"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.05e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"45.8","Tissue RNA - adrenal gland [nTPM]":"23.5","Tissue RNA - amygdala [nTPM]":"72.4","Tissue RNA - appendix [nTPM]":"23.2","Tissue RNA - basal ganglia [nTPM]":"90.5","Tissue RNA - bone marrow [nTPM]":"21.7","Tissue RNA - breast [nTPM]":"36.3","Tissue RNA - cerebellum [nTPM]":"85.0","Tissue RNA - cerebral cortex [nTPM]":"80.7","Tissue RNA - cervix [nTPM]":"36.1","Tissue RNA - choroid plexus [nTPM]":"45.5","Tissue RNA - colon [nTPM]":"44.2","Tissue RNA - duodenum [nTPM]":"5.8","Tissue RNA - endometrium 1 [nTPM]":"38.5","Tissue RNA - epididymis [nTPM]":"14.1","Tissue RNA - esophagus [nTPM]":"17.4","Tissue RNA - fallopian tube [nTPM]":"37.5","Tissue RNA - gallbladder [nTPM]":"23.3","Tissue RNA - heart muscle [nTPM]":"58.0","Tissue RNA - hippocampal formation [nTPM]":"65.1","Tissue RNA - hypothalamus [nTPM]":"85.4","Tissue RNA - kidney [nTPM]":"25.5","Tissue RNA - liver [nTPM]":"15.7","Tissue RNA - lung [nTPM]":"46.1","Tissue RNA - lymph node [nTPM]":"16.8","Tissue RNA - medulla oblongata [nTPM]":"81.5","Tissue RNA - midbrain [nTPM]":"86.6","Tissue RNA - ovary [nTPM]":"30.2","Tissue RNA - pancreas [nTPM]":"23.2","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"20.5","Tissue RNA - placenta [nTPM]":"28.8","Tissue RNA - pons [nTPM]":"77.0","Tissue RNA - prostate [nTPM]":"24.5","Tissue RNA - rectum [nTPM]":"12.9","Tissue RNA - retina [nTPM]":"34.7","Tissue RNA - salivary gland [nTPM]":"19.5","Tissue RNA - seminal vesicle [nTPM]":"40.0","Tissue RNA - skeletal muscle [nTPM]":"26.7","Tissue RNA - skin 1 [nTPM]":"17.3","Tissue RNA - small intestine [nTPM]":"20.2","Tissue RNA - smooth muscle [nTPM]":"47.5","Tissue RNA - spinal cord [nTPM]":"74.9","Tissue RNA - spleen [nTPM]":"31.4","Tissue RNA - stomach 1 [nTPM]":"23.7","Tissue RNA - testis [nTPM]":"15.8","Tissue RNA - thalamus [nTPM]":"87.3","Tissue RNA - thymus [nTPM]":"28.0","Tissue RNA - thyroid gland [nTPM]":"22.0","Tissue RNA - tongue [nTPM]":"33.7","Tissue RNA - tonsil [nTPM]":"15.9","Tissue RNA - urinary bladder [nTPM]":"40.4","Tissue RNA - vagina [nTPM]":"25.1","Tissue RNA - white matter [nTPM]":"81.3","Cell RNA - A-431 [nTPM]":"18.8","Cell RNA - A549 [nTPM]":"23.3","Cell RNA - AF22 [nTPM]":"63.7","Cell RNA - AN3-CA [nTPM]":"56.1","Cell RNA - ASC diff [nTPM]":"113.0","Cell RNA - ASC TERT1 [nTPM]":"92.0","Cell RNA - BEWO [nTPM]":"61.7","Cell RNA - BJ [nTPM]":"69.2","Cell RNA - BJ hTERT+ [nTPM]":"99.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"85.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"104.5","Cell RNA - CACO-2 [nTPM]":"16.4","Cell RNA - CAPAN-2 [nTPM]":"13.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"30.5","Cell RNA - fHDF\/TERT166 [nTPM]":"129.0","Cell RNA - GAMG [nTPM]":"82.4","Cell RNA - HaCaT [nTPM]":"12.7","Cell RNA - HAP1 [nTPM]":"64.3","Cell RNA - HBEC3-KT [nTPM]":"22.5","Cell RNA - HBF TERT88 [nTPM]":"111.4","Cell RNA - HDLM-2 [nTPM]":"73.0","Cell RNA - HEK 293 [nTPM]":"30.9","Cell RNA - HEL [nTPM]":"6.2","Cell RNA - HeLa [nTPM]":"32.2","Cell RNA - Hep G2 [nTPM]":"34.5","Cell RNA - HHSteC [nTPM]":"61.0","Cell RNA - HL-60 [nTPM]":"34.4","Cell RNA - HMC-1 [nTPM]":"13.9","Cell RNA - HSkMC [nTPM]":"76.8","Cell RNA - hTCEpi [nTPM]":"11.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"51.1","Cell RNA - hTERT-HME1 [nTPM]":"74.6","Cell RNA - hTERT-RPE1 [nTPM]":"59.7","Cell RNA - HUVEC TERT2 [nTPM]":"83.8","Cell RNA - JURKAT [nTPM]":"21.9","Cell RNA - K-562 [nTPM]":"33.6","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"101.9","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"19.4","Cell RNA - NB-4 [nTPM]":"15.1","Cell RNA - NTERA-2 [nTPM]":"19.7","Cell RNA - OE19 [nTPM]":"3.2","Cell RNA - PC-3 [nTPM]":"28.6","Cell RNA - REH [nTPM]":"34.2","Cell RNA - RH-30 [nTPM]":"46.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"41.6","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"15.9","Cell RNA - SH-SY5Y [nTPM]":"32.1","Cell RNA - SiHa [nTPM]":"65.8","Cell RNA - SK-BR-3 [nTPM]":"29.7","Cell RNA - SK-MEL-30 [nTPM]":"27.2","Cell RNA - SuSa [nTPM]":"70.4","Cell RNA - T-47d [nTPM]":"15.7","Cell RNA - THP-1 [nTPM]":"24.6","Cell RNA - TIME [nTPM]":"59.2","Cell RNA - U-138 MG [nTPM]":"63.0","Cell RNA - U-2 OS [nTPM]":"41.0","Cell RNA - U-2197 [nTPM]":"78.7","Cell RNA - U-251 MG [nTPM]":"47.3","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"18.7","Cell RNA - U-87 MG [nTPM]":"63.4","Cell RNA - U-937 [nTPM]":"14.1","Cell RNA - WM-115 [nTPM]":"51.9","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"5.0","Blood RNA - eosinophil [nTPM]":"5.7","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"6.3","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"4.6","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"10.8","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"9.2","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"72.4","Brain RNA - basal ganglia [nTPM]":"90.5","Brain RNA - cerebellum [nTPM]":"85.0","Brain RNA - cerebral cortex [nTPM]":"80.7","Brain RNA - hippocampal formation [nTPM]":"65.1","Brain RNA - hypothalamus [nTPM]":"85.4","Brain RNA - medulla oblongata [nTPM]":"81.5","Brain RNA - midbrain [nTPM]":"86.6","Brain RNA - pons [nTPM]":"77.0","Brain RNA - spinal cord [nTPM]":"74.9","Brain RNA - thalamus [nTPM]":"87.3","Brain RNA - white matter [nTPM]":"81.3","Single Cell Type RNA - Adipocytes [nTPM]":"34.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.5","Single Cell Type RNA - Astrocytes [nTPM]":"43.8","Single Cell Type RNA - B-cells [nTPM]":"7.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"9.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"8.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.8","Single Cell Type RNA - Endothelial cells [nTPM]":"31.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.1","Single Cell Type RNA - Fibroblasts [nTPM]":"27.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"57.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"11.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"10.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.8","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"36.3","Single Cell Type RNA - Langerhans cells [nTPM]":"63.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"21.5","Single Cell Type RNA - Macrophages [nTPM]":"48.9","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"68.4","Single Cell Type RNA - monocytes [nTPM]":"41.1","Single Cell Type RNA - Muller glia cells [nTPM]":"11.6","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"136.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"287.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.6","Single Cell Type RNA - Spermatocytes [nTPM]":"7.9","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.2","Single Cell Type RNA - T-cells [nTPM]":"6.3","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"15.0"},{"Gene":"DEPDC5","Gene synonym":["DEP.5","KIAA0645"],"Ensembl":"ENSG00000100150","Gene description":"DEP domain containing 5, GATOR1 subcomplex subunit","Uniprot":["O75140"],"Chromosome":"22","Position":"31753867-31908033","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"31.9","Inhibitory neurons":"29.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"34.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"34.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"31.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054969","HPA055619"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054969":"AB_2682655","HPA055619":"AB_2682864"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.46e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.86e-5"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"7.7","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"5.1","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"5.6","Tissue RNA - cerebellum [nTPM]":"8.7","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"6.6","Tissue RNA - gallbladder [nTPM]":"3.5","Tissue RNA - heart muscle [nTPM]":"4.8","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"5.5","Tissue RNA - liver [nTPM]":"9.9","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"11.3","Tissue RNA - pancreas [nTPM]":"4.2","Tissue RNA - parathyroid gland [nTPM]":"4.9","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"4.0","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"9.4","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"7.4","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"6.6","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"5.0","Cell RNA - AF22 [nTPM]":"9.1","Cell RNA - AN3-CA [nTPM]":"5.7","Cell RNA - ASC diff [nTPM]":"4.5","Cell RNA - ASC TERT1 [nTPM]":"4.7","Cell RNA - BEWO [nTPM]":"7.4","Cell RNA - BJ [nTPM]":"3.9","Cell RNA - BJ hTERT+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.8","Cell RNA - CACO-2 [nTPM]":"6.8","Cell RNA - CAPAN-2 [nTPM]":"3.4","Cell RNA - Daudi [nTPM]":"13.0","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"5.5","Cell RNA - GAMG [nTPM]":"4.1","Cell RNA - HaCaT [nTPM]":"5.8","Cell RNA - HAP1 [nTPM]":"6.3","Cell RNA - HBEC3-KT [nTPM]":"6.3","Cell RNA - HBF TERT88 [nTPM]":"9.1","Cell RNA - HDLM-2 [nTPM]":"6.7","Cell RNA - HEK 293 [nTPM]":"5.8","Cell RNA - HEL [nTPM]":"6.1","Cell RNA - HeLa [nTPM]":"6.1","Cell RNA - Hep G2 [nTPM]":"6.7","Cell RNA - HHSteC [nTPM]":"4.4","Cell RNA - HL-60 [nTPM]":"20.6","Cell RNA - HMC-1 [nTPM]":"19.0","Cell RNA - HSkMC [nTPM]":"5.2","Cell RNA - hTCEpi [nTPM]":"3.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.6","Cell RNA - hTERT-HME1 [nTPM]":"4.8","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"9.3","Cell RNA - JURKAT [nTPM]":"4.8","Cell RNA - K-562 [nTPM]":"4.3","Cell RNA - Karpas-707 [nTPM]":"3.9","Cell RNA - LHCN-M2 [nTPM]":"7.3","Cell RNA - MCF7 [nTPM]":"5.5","Cell RNA - MOLT-4 [nTPM]":"5.8","Cell RNA - NB-4 [nTPM]":"5.8","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"9.9","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"11.2","Cell RNA - RH-30 [nTPM]":"10.0","Cell RNA - RPMI-8226 [nTPM]":"7.4","Cell RNA - RPTEC TERT1 [nTPM]":"6.0","Cell RNA - RT4 [nTPM]":"12.0","Cell RNA - SCLC-21H [nTPM]":"6.0","Cell RNA - SH-SY5Y [nTPM]":"6.7","Cell RNA - SiHa [nTPM]":"7.8","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"5.2","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"4.4","Cell RNA - THP-1 [nTPM]":"11.5","Cell RNA - TIME [nTPM]":"8.0","Cell RNA - U-138 MG [nTPM]":"5.0","Cell RNA - U-2 OS [nTPM]":"6.0","Cell RNA - U-2197 [nTPM]":"5.2","Cell RNA - U-251 MG [nTPM]":"3.8","Cell RNA - U-266\/70 [nTPM]":"5.8","Cell RNA - U-266\/84 [nTPM]":"5.7","Cell RNA - U-698 [nTPM]":"31.5","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"6.0","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"34.8","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"15.2","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"6.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"4.2","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"4.2","Blood RNA - non-classical monocyte [nTPM]":"3.7","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"8.7","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"4.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"12.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"5.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - dendritic cells [nTPM]":"4.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.1","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.5","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"18.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"4.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.2","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"6.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"4.2","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"5.6","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"4.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"5.3","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"DHDDS","Gene synonym":["DS","FLJ13102","hCIT","HDS","RP59"],"Ensembl":"ENSG00000117682","Gene description":"Dehydrodolichyl diphosphate synthase subunit","Uniprot":["Q86SQ9"],"Chromosome":"1","Position":"26432282-26471306","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"256.5","Early spermatids":"99.1","Rod photoreceptor cells":"106.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026721","HPA026727"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA026721":"AB_1847643","HPA026727":"AB_1847644"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Tissue RNA - adipose tissue [nTPM]":"57.3","Tissue RNA - adrenal gland [nTPM]":"19.6","Tissue RNA - amygdala [nTPM]":"12.3","Tissue RNA - appendix [nTPM]":"18.9","Tissue RNA - basal ganglia [nTPM]":"11.8","Tissue RNA - bone marrow [nTPM]":"12.4","Tissue RNA - breast [nTPM]":"22.7","Tissue RNA - cerebellum [nTPM]":"32.5","Tissue RNA - cerebral cortex [nTPM]":"14.0","Tissue RNA - cervix [nTPM]":"14.6","Tissue RNA - choroid plexus [nTPM]":"14.6","Tissue RNA - colon [nTPM]":"37.3","Tissue RNA - duodenum [nTPM]":"19.1","Tissue RNA - endometrium 1 [nTPM]":"13.5","Tissue RNA - epididymis [nTPM]":"38.5","Tissue RNA - esophagus [nTPM]":"26.3","Tissue RNA - fallopian tube [nTPM]":"12.9","Tissue RNA - gallbladder [nTPM]":"15.9","Tissue RNA - heart muscle [nTPM]":"19.8","Tissue RNA - hippocampal formation [nTPM]":"12.8","Tissue RNA - hypothalamus [nTPM]":"13.3","Tissue RNA - kidney [nTPM]":"25.5","Tissue RNA - liver [nTPM]":"22.0","Tissue RNA - lung [nTPM]":"13.9","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"15.5","Tissue RNA - midbrain [nTPM]":"16.9","Tissue RNA - ovary [nTPM]":"11.4","Tissue RNA - pancreas [nTPM]":"18.5","Tissue RNA - parathyroid gland [nTPM]":"39.8","Tissue RNA - pituitary gland [nTPM]":"20.9","Tissue RNA - placenta [nTPM]":"12.6","Tissue RNA - pons [nTPM]":"18.8","Tissue RNA - prostate [nTPM]":"14.1","Tissue RNA - rectum [nTPM]":"38.8","Tissue RNA - retina [nTPM]":"37.8","Tissue RNA - salivary gland [nTPM]":"43.3","Tissue RNA - seminal vesicle [nTPM]":"14.0","Tissue RNA - skeletal muscle [nTPM]":"13.5","Tissue RNA - skin 1 [nTPM]":"21.2","Tissue RNA - small intestine [nTPM]":"18.2","Tissue RNA - smooth muscle [nTPM]":"18.4","Tissue RNA - spinal cord [nTPM]":"9.0","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"23.3","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"14.1","Tissue RNA - thymus [nTPM]":"14.1","Tissue RNA - thyroid gland [nTPM]":"19.1","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"20.8","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"14.4","Tissue RNA - white matter [nTPM]":"12.2","Cell RNA - A-431 [nTPM]":"34.2","Cell RNA - A549 [nTPM]":"24.8","Cell RNA - AF22 [nTPM]":"20.6","Cell RNA - AN3-CA [nTPM]":"23.8","Cell RNA - ASC diff [nTPM]":"36.1","Cell RNA - ASC TERT1 [nTPM]":"28.2","Cell RNA - BEWO [nTPM]":"28.4","Cell RNA - BJ [nTPM]":"54.9","Cell RNA - BJ hTERT+ [nTPM]":"33.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.6","Cell RNA - CACO-2 [nTPM]":"37.4","Cell RNA - CAPAN-2 [nTPM]":"34.6","Cell RNA - Daudi [nTPM]":"38.4","Cell RNA - EFO-21 [nTPM]":"33.3","Cell RNA - fHDF\/TERT166 [nTPM]":"57.2","Cell RNA - GAMG [nTPM]":"30.0","Cell RNA - HaCaT [nTPM]":"24.1","Cell RNA - HAP1 [nTPM]":"25.4","Cell RNA - HBEC3-KT [nTPM]":"42.8","Cell RNA - HBF TERT88 [nTPM]":"42.9","Cell RNA - HDLM-2 [nTPM]":"22.7","Cell RNA - HEK 293 [nTPM]":"13.9","Cell RNA - HEL [nTPM]":"38.0","Cell RNA - HeLa [nTPM]":"66.9","Cell RNA - Hep G2 [nTPM]":"30.8","Cell RNA - HHSteC [nTPM]":"39.3","Cell RNA - HL-60 [nTPM]":"41.4","Cell RNA - HMC-1 [nTPM]":"51.5","Cell RNA - HSkMC [nTPM]":"40.3","Cell RNA - hTCEpi [nTPM]":"27.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"59.1","Cell RNA - hTERT-HME1 [nTPM]":"32.2","Cell RNA - hTERT-RPE1 [nTPM]":"29.4","Cell RNA - HUVEC TERT2 [nTPM]":"51.2","Cell RNA - JURKAT [nTPM]":"26.7","Cell RNA - K-562 [nTPM]":"27.3","Cell RNA - Karpas-707 [nTPM]":"41.0","Cell RNA - LHCN-M2 [nTPM]":"39.7","Cell RNA - MCF7 [nTPM]":"19.4","Cell RNA - MOLT-4 [nTPM]":"23.1","Cell RNA - NB-4 [nTPM]":"20.2","Cell RNA - NTERA-2 [nTPM]":"26.3","Cell RNA - OE19 [nTPM]":"53.1","Cell RNA - PC-3 [nTPM]":"36.2","Cell RNA - REH [nTPM]":"25.3","Cell RNA - RH-30 [nTPM]":"33.4","Cell RNA - RPMI-8226 [nTPM]":"31.2","Cell RNA - RPTEC TERT1 [nTPM]":"25.4","Cell RNA - RT4 [nTPM]":"28.8","Cell RNA - SCLC-21H [nTPM]":"24.4","Cell RNA - SH-SY5Y [nTPM]":"19.4","Cell RNA - SiHa [nTPM]":"36.4","Cell RNA - SK-BR-3 [nTPM]":"38.0","Cell RNA - SK-MEL-30 [nTPM]":"26.6","Cell RNA - SuSa [nTPM]":"26.8","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"20.9","Cell RNA - TIME [nTPM]":"63.0","Cell RNA - U-138 MG [nTPM]":"30.1","Cell RNA - U-2 OS [nTPM]":"26.3","Cell RNA - U-2197 [nTPM]":"60.4","Cell RNA - U-251 MG [nTPM]":"32.0","Cell RNA - U-266\/70 [nTPM]":"48.1","Cell RNA - U-266\/84 [nTPM]":"72.4","Cell RNA - U-698 [nTPM]":"39.5","Cell RNA - U-87 MG [nTPM]":"43.0","Cell RNA - U-937 [nTPM]":"54.0","Cell RNA - WM-115 [nTPM]":"26.8","Blood RNA - basophil [nTPM]":"9.4","Blood RNA - classical monocyte [nTPM]":"16.1","Blood RNA - eosinophil [nTPM]":"9.6","Blood RNA - gdT-cell [nTPM]":"13.8","Blood RNA - intermediate monocyte [nTPM]":"23.6","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"13.2","Blood RNA - memory CD4 T-cell [nTPM]":"9.0","Blood RNA - memory CD8 T-cell [nTPM]":"9.1","Blood RNA - myeloid DC [nTPM]":"13.6","Blood RNA - naive B-cell [nTPM]":"10.2","Blood RNA - naive CD4 T-cell [nTPM]":"7.4","Blood RNA - naive CD8 T-cell [nTPM]":"10.9","Blood RNA - neutrophil [nTPM]":"13.0","Blood RNA - NK-cell [nTPM]":"10.1","Blood RNA - non-classical monocyte [nTPM]":"23.1","Blood RNA - plasmacytoid DC [nTPM]":"11.5","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"10.5","Brain RNA - amygdala [nTPM]":"12.3","Brain RNA - basal ganglia [nTPM]":"11.8","Brain RNA - cerebellum [nTPM]":"32.5","Brain RNA - cerebral cortex [nTPM]":"14.0","Brain RNA - hippocampal formation [nTPM]":"12.8","Brain RNA - hypothalamus [nTPM]":"13.3","Brain RNA - medulla oblongata [nTPM]":"15.5","Brain RNA - midbrain [nTPM]":"16.9","Brain RNA - pons [nTPM]":"18.8","Brain RNA - spinal cord [nTPM]":"9.0","Brain RNA - thalamus [nTPM]":"14.1","Brain RNA - white matter [nTPM]":"12.2","Single Cell Type RNA - Adipocytes [nTPM]":"9.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"13.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"29.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"13.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"256.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - dendritic cells [nTPM]":"13.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"76.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"99.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.9","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.9","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.4","Single Cell Type RNA - Fibroblasts [nTPM]":"11.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.0","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"14.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"13.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.5","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"11.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.1","Single Cell Type RNA - Late spermatids [nTPM]":"23.4","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"10.5","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"34.4","Single Cell Type RNA - Muller glia cells [nTPM]":"16.3","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.6","Single Cell Type RNA - Paneth cells [nTPM]":"40.3","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"106.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.5","Single Cell Type RNA - Spermatocytes [nTPM]":"13.2","Single Cell Type RNA - Spermatogonia [nTPM]":"13.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.4","Single Cell Type RNA - T-cells [nTPM]":"10.3","Single Cell Type RNA - Theca cells [nTPM]":"15.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"DHTKD1","Gene synonym":["CMT2Q","DKFZP762M115","KIAA1630","MGC3090"],"Ensembl":"ENSG00000181192","Gene description":"Dehydrogenase E1 and transketolase domain containing 1","Uniprot":["Q96HY7"],"Chromosome":"10","Position":"12068954-12123221","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"129.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"227.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"T-47d":"102.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037949","HPA037950","HPA066098"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA037949":"AB_2675752","HPA037950":"AB_10673650","HPA066098":"AB_2685617"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.7","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"8.4","Tissue RNA - cerebellum [nTPM]":"12.6","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"11.9","Tissue RNA - colon [nTPM]":"10.1","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"6.2","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"7.6","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"42.7","Tissue RNA - liver [nTPM]":"129.5","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"10.0","Tissue RNA - pancreas [nTPM]":"18.0","Tissue RNA - parathyroid gland [nTPM]":"12.7","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"7.7","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"12.9","Tissue RNA - rectum [nTPM]":"10.8","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"13.1","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"18.7","Tissue RNA - skin 1 [nTPM]":"5.6","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"8.8","Tissue RNA - spleen [nTPM]":"7.8","Tissue RNA - stomach 1 [nTPM]":"10.9","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"11.6","Tissue RNA - tongue [nTPM]":"23.1","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"6.3","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"11.4","Cell RNA - A-431 [nTPM]":"27.0","Cell RNA - A549 [nTPM]":"20.4","Cell RNA - AF22 [nTPM]":"29.8","Cell RNA - AN3-CA [nTPM]":"23.8","Cell RNA - ASC diff [nTPM]":"18.2","Cell RNA - ASC TERT1 [nTPM]":"10.8","Cell RNA - BEWO [nTPM]":"35.9","Cell RNA - BJ [nTPM]":"13.3","Cell RNA - BJ hTERT+ [nTPM]":"8.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.6","Cell RNA - CACO-2 [nTPM]":"13.1","Cell RNA - CAPAN-2 [nTPM]":"15.7","Cell RNA - Daudi [nTPM]":"19.3","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"8.4","Cell RNA - GAMG [nTPM]":"10.8","Cell RNA - HaCaT [nTPM]":"37.4","Cell RNA - HAP1 [nTPM]":"31.6","Cell RNA - HBEC3-KT [nTPM]":"10.4","Cell RNA - HBF TERT88 [nTPM]":"26.6","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"14.2","Cell RNA - HEL [nTPM]":"10.6","Cell RNA - HeLa [nTPM]":"7.7","Cell RNA - Hep G2 [nTPM]":"10.1","Cell RNA - HHSteC [nTPM]":"17.8","Cell RNA - HL-60 [nTPM]":"4.2","Cell RNA - HMC-1 [nTPM]":"3.8","Cell RNA - HSkMC [nTPM]":"13.3","Cell RNA - hTCEpi [nTPM]":"7.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.7","Cell RNA - hTERT-HME1 [nTPM]":"5.5","Cell RNA - hTERT-RPE1 [nTPM]":"9.2","Cell RNA - HUVEC TERT2 [nTPM]":"13.0","Cell RNA - JURKAT [nTPM]":"23.1","Cell RNA - K-562 [nTPM]":"16.7","Cell RNA - Karpas-707 [nTPM]":"15.1","Cell RNA - LHCN-M2 [nTPM]":"6.3","Cell RNA - MCF7 [nTPM]":"52.3","Cell RNA - MOLT-4 [nTPM]":"14.4","Cell RNA - NB-4 [nTPM]":"7.7","Cell RNA - NTERA-2 [nTPM]":"16.7","Cell RNA - OE19 [nTPM]":"24.9","Cell RNA - PC-3 [nTPM]":"4.7","Cell RNA - REH [nTPM]":"24.3","Cell RNA - RH-30 [nTPM]":"9.7","Cell RNA - RPMI-8226 [nTPM]":"16.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.2","Cell RNA - RT4 [nTPM]":"6.4","Cell RNA - SCLC-21H [nTPM]":"7.7","Cell RNA - SH-SY5Y [nTPM]":"34.9","Cell RNA - SiHa [nTPM]":"26.3","Cell RNA - SK-BR-3 [nTPM]":"46.3","Cell RNA - SK-MEL-30 [nTPM]":"15.4","Cell RNA - SuSa [nTPM]":"31.7","Cell RNA - T-47d [nTPM]":"102.2","Cell RNA - THP-1 [nTPM]":"15.2","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"7.5","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"15.8","Cell RNA - U-251 MG [nTPM]":"9.9","Cell RNA - U-266\/70 [nTPM]":"13.4","Cell RNA - U-266\/84 [nTPM]":"10.3","Cell RNA - U-698 [nTPM]":"12.6","Cell RNA - U-87 MG [nTPM]":"9.7","Cell RNA - U-937 [nTPM]":"7.4","Cell RNA - WM-115 [nTPM]":"12.8","Blood RNA - basophil [nTPM]":"23.8","Blood RNA - classical monocyte [nTPM]":"6.8","Blood RNA - eosinophil [nTPM]":"15.4","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"9.2","Blood RNA - MAIT T-cell [nTPM]":"4.5","Blood RNA - memory B-cell [nTPM]":"13.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"11.9","Blood RNA - naive B-cell [nTPM]":"9.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"19.4","Blood RNA - NK-cell [nTPM]":"14.3","Blood RNA - non-classical monocyte [nTPM]":"17.0","Blood RNA - plasmacytoid DC [nTPM]":"17.3","Blood RNA - T-reg [nTPM]":"5.7","Blood RNA - total PBMC [nTPM]":"4.9","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"12.6","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"7.6","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"8.8","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"11.4","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.8","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"21.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"13.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"7.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.4","Single Cell Type RNA - dendritic cells [nTPM]":"23.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"10.9","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.3","Single Cell Type RNA - Erythroid cells [nTPM]":"21.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.1","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.8","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"45.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"227.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.3","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.3","Single Cell Type RNA - Langerhans cells [nTPM]":"10.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"13.4","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.6","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"22.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"62.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.4","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.5","Single Cell Type RNA - T-cells [nTPM]":"8.4","Single Cell Type RNA - Theca cells [nTPM]":"21.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.6","Single Cell Type RNA - Urothelial cells [nTPM]":"7.8"},{"Gene":"DHX38","Gene synonym":["DDX38","hPrp16","KIAA0224","PRP16","PRPF16"],"Ensembl":"ENSG00000140829","Gene description":"DEAH-box helicase 38","Uniprot":["Q92620"],"Chromosome":"16","Position":"72093613-72112912","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041347","HPA041604"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA041347":"AB_10796571","HPA041604":"AB_2677577"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"25.8","Tissue RNA - adrenal gland [nTPM]":"18.7","Tissue RNA - amygdala [nTPM]":"22.4","Tissue RNA - appendix [nTPM]":"22.8","Tissue RNA - basal ganglia [nTPM]":"24.4","Tissue RNA - bone marrow [nTPM]":"39.7","Tissue RNA - breast [nTPM]":"23.8","Tissue RNA - cerebellum [nTPM]":"22.2","Tissue RNA - cerebral cortex [nTPM]":"24.7","Tissue RNA - cervix [nTPM]":"25.1","Tissue RNA - choroid plexus [nTPM]":"25.9","Tissue RNA - colon [nTPM]":"24.8","Tissue RNA - duodenum [nTPM]":"19.6","Tissue RNA - endometrium 1 [nTPM]":"25.5","Tissue RNA - epididymis [nTPM]":"10.7","Tissue RNA - esophagus [nTPM]":"24.2","Tissue RNA - fallopian tube [nTPM]":"23.8","Tissue RNA - gallbladder [nTPM]":"15.0","Tissue RNA - heart muscle [nTPM]":"27.0","Tissue RNA - hippocampal formation [nTPM]":"21.5","Tissue RNA - hypothalamus [nTPM]":"21.6","Tissue RNA - kidney [nTPM]":"19.6","Tissue RNA - liver [nTPM]":"24.0","Tissue RNA - lung [nTPM]":"23.9","Tissue RNA - lymph node [nTPM]":"27.8","Tissue RNA - medulla oblongata [nTPM]":"23.2","Tissue RNA - midbrain [nTPM]":"23.2","Tissue RNA - ovary [nTPM]":"30.6","Tissue RNA - pancreas [nTPM]":"20.2","Tissue RNA - parathyroid gland [nTPM]":"22.9","Tissue RNA - pituitary gland [nTPM]":"19.3","Tissue RNA - placenta [nTPM]":"18.6","Tissue RNA - pons [nTPM]":"22.5","Tissue RNA - prostate [nTPM]":"20.9","Tissue RNA - rectum [nTPM]":"16.1","Tissue RNA - retina [nTPM]":"13.2","Tissue RNA - salivary gland [nTPM]":"21.1","Tissue RNA - seminal vesicle [nTPM]":"14.4","Tissue RNA - skeletal muscle [nTPM]":"39.9","Tissue RNA - skin 1 [nTPM]":"27.6","Tissue RNA - small intestine [nTPM]":"27.3","Tissue RNA - smooth muscle [nTPM]":"17.6","Tissue RNA - spinal cord [nTPM]":"22.2","Tissue RNA - spleen [nTPM]":"30.4","Tissue RNA - stomach 1 [nTPM]":"22.5","Tissue RNA - testis [nTPM]":"21.3","Tissue RNA - thalamus [nTPM]":"23.5","Tissue RNA - thymus [nTPM]":"24.2","Tissue RNA - thyroid gland [nTPM]":"22.8","Tissue RNA - tongue [nTPM]":"21.4","Tissue RNA - tonsil [nTPM]":"23.1","Tissue RNA - urinary bladder [nTPM]":"23.7","Tissue RNA - vagina [nTPM]":"22.9","Tissue RNA - white matter [nTPM]":"25.0","Cell RNA - A-431 [nTPM]":"38.5","Cell RNA - A549 [nTPM]":"55.0","Cell RNA - AF22 [nTPM]":"39.4","Cell RNA - AN3-CA [nTPM]":"21.9","Cell RNA - ASC diff [nTPM]":"33.4","Cell RNA - ASC TERT1 [nTPM]":"25.8","Cell RNA - BEWO [nTPM]":"51.1","Cell RNA - BJ [nTPM]":"33.6","Cell RNA - BJ hTERT+ [nTPM]":"32.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.8","Cell RNA - CACO-2 [nTPM]":"66.4","Cell RNA - CAPAN-2 [nTPM]":"37.5","Cell RNA - Daudi [nTPM]":"50.5","Cell RNA - EFO-21 [nTPM]":"29.2","Cell RNA - fHDF\/TERT166 [nTPM]":"50.9","Cell RNA - GAMG [nTPM]":"27.0","Cell RNA - HaCaT [nTPM]":"48.6","Cell RNA - HAP1 [nTPM]":"46.3","Cell RNA - HBEC3-KT [nTPM]":"45.8","Cell RNA - HBF TERT88 [nTPM]":"38.0","Cell RNA - HDLM-2 [nTPM]":"25.3","Cell RNA - HEK 293 [nTPM]":"50.0","Cell RNA - HEL [nTPM]":"38.7","Cell RNA - HeLa [nTPM]":"48.9","Cell RNA - Hep G2 [nTPM]":"92.5","Cell RNA - HHSteC [nTPM]":"30.8","Cell RNA - HL-60 [nTPM]":"46.9","Cell RNA - HMC-1 [nTPM]":"66.7","Cell RNA - HSkMC [nTPM]":"35.6","Cell RNA - hTCEpi [nTPM]":"41.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"66.1","Cell RNA - hTERT-HME1 [nTPM]":"47.4","Cell RNA - hTERT-RPE1 [nTPM]":"25.9","Cell RNA - HUVEC TERT2 [nTPM]":"42.9","Cell RNA - JURKAT [nTPM]":"35.7","Cell RNA - K-562 [nTPM]":"58.9","Cell RNA - Karpas-707 [nTPM]":"22.9","Cell RNA - LHCN-M2 [nTPM]":"30.6","Cell RNA - MCF7 [nTPM]":"112.8","Cell RNA - MOLT-4 [nTPM]":"43.9","Cell RNA - NB-4 [nTPM]":"53.1","Cell RNA - NTERA-2 [nTPM]":"49.7","Cell RNA - OE19 [nTPM]":"23.9","Cell RNA - PC-3 [nTPM]":"30.9","Cell RNA - REH [nTPM]":"55.8","Cell RNA - RH-30 [nTPM]":"27.1","Cell RNA - RPMI-8226 [nTPM]":"49.9","Cell RNA - RPTEC TERT1 [nTPM]":"24.0","Cell RNA - RT4 [nTPM]":"35.6","Cell RNA - SCLC-21H [nTPM]":"35.6","Cell RNA - SH-SY5Y [nTPM]":"38.9","Cell RNA - SiHa [nTPM]":"43.8","Cell RNA - SK-BR-3 [nTPM]":"20.3","Cell RNA - SK-MEL-30 [nTPM]":"24.5","Cell RNA - SuSa [nTPM]":"22.5","Cell RNA - T-47d [nTPM]":"36.8","Cell RNA - THP-1 [nTPM]":"38.4","Cell RNA - TIME [nTPM]":"49.4","Cell RNA - U-138 MG [nTPM]":"46.6","Cell RNA - U-2 OS [nTPM]":"40.8","Cell RNA - U-2197 [nTPM]":"34.8","Cell RNA - U-251 MG [nTPM]":"37.3","Cell RNA - U-266\/70 [nTPM]":"56.2","Cell RNA - U-266\/84 [nTPM]":"47.6","Cell RNA - U-698 [nTPM]":"96.7","Cell RNA - U-87 MG [nTPM]":"43.9","Cell RNA - U-937 [nTPM]":"32.1","Cell RNA - WM-115 [nTPM]":"37.5","Blood RNA - basophil [nTPM]":"7.1","Blood RNA - classical monocyte [nTPM]":"6.2","Blood RNA - eosinophil [nTPM]":"7.1","Blood RNA - gdT-cell [nTPM]":"11.3","Blood RNA - intermediate monocyte [nTPM]":"8.3","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"8.1","Blood RNA - memory CD4 T-cell [nTPM]":"6.8","Blood RNA - memory CD8 T-cell [nTPM]":"8.2","Blood RNA - myeloid DC [nTPM]":"6.2","Blood RNA - naive B-cell [nTPM]":"6.0","Blood RNA - naive CD4 T-cell [nTPM]":"7.4","Blood RNA - naive CD8 T-cell [nTPM]":"7.9","Blood RNA - neutrophil [nTPM]":"6.4","Blood RNA - NK-cell [nTPM]":"8.8","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"8.6","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"22.4","Brain RNA - basal ganglia [nTPM]":"24.4","Brain RNA - cerebellum [nTPM]":"22.2","Brain RNA - cerebral cortex [nTPM]":"24.7","Brain RNA - hippocampal formation [nTPM]":"21.5","Brain RNA - hypothalamus [nTPM]":"21.6","Brain RNA - medulla oblongata [nTPM]":"23.2","Brain RNA - midbrain [nTPM]":"23.2","Brain RNA - pons [nTPM]":"22.5","Brain RNA - spinal cord [nTPM]":"22.2","Brain RNA - thalamus [nTPM]":"23.5","Brain RNA - white matter [nTPM]":"25.0","Single Cell Type RNA - Adipocytes [nTPM]":"22.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.3","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"24.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"30.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"22.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.0","Single Cell Type RNA - dendritic cells [nTPM]":"33.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"14.5","Single Cell Type RNA - Early spermatids [nTPM]":"9.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.0","Single Cell Type RNA - Endothelial cells [nTPM]":"22.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.5","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.3","Single Cell Type RNA - Fibroblasts [nTPM]":"17.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.6","Single Cell Type RNA - granulocytes [nTPM]":"43.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"13.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.9","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.2","Single Cell Type RNA - Langerhans cells [nTPM]":"13.9","Single Cell Type RNA - Late spermatids [nTPM]":"11.0","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"20.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"16.9","Single Cell Type RNA - Muller glia cells [nTPM]":"17.9","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.7","Single Cell Type RNA - Paneth cells [nTPM]":"17.1","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"22.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.1","Single Cell Type RNA - Spermatocytes [nTPM]":"25.5","Single Cell Type RNA - Spermatogonia [nTPM]":"17.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.4","Single Cell Type RNA - T-cells [nTPM]":"28.2","Single Cell Type RNA - Theca cells [nTPM]":"20.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"DIABLO","Gene synonym":["DFNA64","DIABLO-S","FLJ10537","FLJ25049","SMAC"],"Ensembl":"ENSG00000184047","Gene description":"Diablo IAP-binding mitochondrial protein","Uniprot":["Q9NR28"],"Chromosome":"12","Position":"122207663-122227456","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"31.3","Plasma cells":"29.2","Squamous epithelial cells":"30.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001825","CAB003857","CAB016688"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB003857":"AB_365498","CAB016688":"AB_1615783","HPA001825":"AB_1857247"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"23.8","Tissue RNA - adrenal gland [nTPM]":"34.3","Tissue RNA - amygdala [nTPM]":"29.8","Tissue RNA - appendix [nTPM]":"17.3","Tissue RNA - basal ganglia [nTPM]":"30.8","Tissue RNA - bone marrow [nTPM]":"32.5","Tissue RNA - breast [nTPM]":"25.3","Tissue RNA - cerebellum [nTPM]":"33.7","Tissue RNA - cerebral cortex [nTPM]":"36.8","Tissue RNA - cervix [nTPM]":"21.4","Tissue RNA - choroid plexus [nTPM]":"30.4","Tissue RNA - colon [nTPM]":"28.7","Tissue RNA - duodenum [nTPM]":"21.7","Tissue RNA - endometrium 1 [nTPM]":"27.0","Tissue RNA - epididymis [nTPM]":"36.1","Tissue RNA - esophagus [nTPM]":"30.8","Tissue RNA - fallopian tube [nTPM]":"23.3","Tissue RNA - gallbladder [nTPM]":"18.0","Tissue RNA - heart muscle [nTPM]":"30.3","Tissue RNA - hippocampal formation [nTPM]":"28.7","Tissue RNA - hypothalamus [nTPM]":"32.0","Tissue RNA - kidney [nTPM]":"34.5","Tissue RNA - liver [nTPM]":"39.6","Tissue RNA - lung [nTPM]":"21.2","Tissue RNA - lymph node [nTPM]":"21.0","Tissue RNA - medulla oblongata [nTPM]":"32.0","Tissue RNA - midbrain [nTPM]":"31.4","Tissue RNA - ovary [nTPM]":"27.8","Tissue RNA - pancreas [nTPM]":"27.7","Tissue RNA - parathyroid gland [nTPM]":"32.2","Tissue RNA - pituitary gland [nTPM]":"41.4","Tissue RNA - placenta [nTPM]":"25.8","Tissue RNA - pons [nTPM]":"32.1","Tissue RNA - prostate [nTPM]":"21.9","Tissue RNA - rectum [nTPM]":"24.5","Tissue RNA - retina [nTPM]":"27.5","Tissue RNA - salivary gland [nTPM]":"28.9","Tissue RNA - seminal vesicle [nTPM]":"19.5","Tissue RNA - skeletal muscle [nTPM]":"37.4","Tissue RNA - skin 1 [nTPM]":"25.4","Tissue RNA - small intestine [nTPM]":"26.9","Tissue RNA - smooth muscle [nTPM]":"20.5","Tissue RNA - spinal cord [nTPM]":"33.6","Tissue RNA - spleen [nTPM]":"24.3","Tissue RNA - stomach 1 [nTPM]":"26.6","Tissue RNA - testis [nTPM]":"53.2","Tissue RNA - thalamus [nTPM]":"31.0","Tissue RNA - thymus [nTPM]":"26.9","Tissue RNA - thyroid gland [nTPM]":"25.8","Tissue RNA - tongue [nTPM]":"34.5","Tissue RNA - tonsil [nTPM]":"24.9","Tissue RNA - urinary bladder [nTPM]":"32.0","Tissue RNA - vagina [nTPM]":"24.5","Tissue RNA - white matter [nTPM]":"33.4","Cell RNA - A-431 [nTPM]":"49.0","Cell RNA - A549 [nTPM]":"94.7","Cell RNA - AF22 [nTPM]":"65.4","Cell RNA - AN3-CA [nTPM]":"44.7","Cell RNA - ASC diff [nTPM]":"45.9","Cell RNA - ASC TERT1 [nTPM]":"44.6","Cell RNA - BEWO [nTPM]":"50.2","Cell RNA - BJ [nTPM]":"49.5","Cell RNA - BJ hTERT+ [nTPM]":"48.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"56.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"50.8","Cell RNA - CACO-2 [nTPM]":"82.4","Cell RNA - CAPAN-2 [nTPM]":"24.9","Cell RNA - Daudi [nTPM]":"59.2","Cell RNA - EFO-21 [nTPM]":"45.4","Cell RNA - fHDF\/TERT166 [nTPM]":"45.2","Cell RNA - GAMG [nTPM]":"42.4","Cell RNA - HaCaT [nTPM]":"47.4","Cell RNA - HAP1 [nTPM]":"72.2","Cell RNA - HBEC3-KT [nTPM]":"59.3","Cell RNA - HBF TERT88 [nTPM]":"67.0","Cell RNA - HDLM-2 [nTPM]":"51.1","Cell RNA - HEK 293 [nTPM]":"56.4","Cell RNA - HEL [nTPM]":"65.2","Cell RNA - HeLa [nTPM]":"36.6","Cell RNA - Hep G2 [nTPM]":"76.7","Cell RNA - HHSteC [nTPM]":"65.3","Cell RNA - HL-60 [nTPM]":"71.0","Cell RNA - HMC-1 [nTPM]":"25.9","Cell RNA - HSkMC [nTPM]":"62.2","Cell RNA - hTCEpi [nTPM]":"41.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"67.3","Cell RNA - hTERT-HME1 [nTPM]":"100.1","Cell RNA - hTERT-RPE1 [nTPM]":"64.4","Cell RNA - HUVEC TERT2 [nTPM]":"66.8","Cell RNA - JURKAT [nTPM]":"57.9","Cell RNA - K-562 [nTPM]":"75.9","Cell RNA - Karpas-707 [nTPM]":"24.5","Cell RNA - LHCN-M2 [nTPM]":"56.1","Cell RNA - MCF7 [nTPM]":"72.4","Cell RNA - MOLT-4 [nTPM]":"58.6","Cell RNA - NB-4 [nTPM]":"103.8","Cell RNA - NTERA-2 [nTPM]":"52.9","Cell RNA - OE19 [nTPM]":"69.5","Cell RNA - PC-3 [nTPM]":"88.0","Cell RNA - REH [nTPM]":"52.3","Cell RNA - RH-30 [nTPM]":"65.2","Cell RNA - RPMI-8226 [nTPM]":"65.4","Cell RNA - RPTEC TERT1 [nTPM]":"64.4","Cell RNA - RT4 [nTPM]":"74.7","Cell RNA - SCLC-21H [nTPM]":"61.7","Cell RNA - SH-SY5Y [nTPM]":"62.6","Cell RNA - SiHa [nTPM]":"66.1","Cell RNA - SK-BR-3 [nTPM]":"26.2","Cell RNA - SK-MEL-30 [nTPM]":"54.8","Cell RNA - SuSa [nTPM]":"73.3","Cell RNA - T-47d [nTPM]":"87.9","Cell RNA - THP-1 [nTPM]":"49.2","Cell RNA - TIME [nTPM]":"46.0","Cell RNA - U-138 MG [nTPM]":"43.7","Cell RNA - U-2 OS [nTPM]":"53.6","Cell RNA - U-2197 [nTPM]":"50.0","Cell RNA - U-251 MG [nTPM]":"45.4","Cell RNA - U-266\/70 [nTPM]":"52.8","Cell RNA - U-266\/84 [nTPM]":"95.5","Cell RNA - U-698 [nTPM]":"84.3","Cell RNA - U-87 MG [nTPM]":"55.8","Cell RNA - U-937 [nTPM]":"53.6","Cell RNA - WM-115 [nTPM]":"58.8","Blood RNA - basophil [nTPM]":"43.3","Blood RNA - classical monocyte [nTPM]":"39.8","Blood RNA - eosinophil [nTPM]":"39.8","Blood RNA - gdT-cell [nTPM]":"39.9","Blood RNA - intermediate monocyte [nTPM]":"41.4","Blood RNA - MAIT T-cell [nTPM]":"37.8","Blood RNA - memory B-cell [nTPM]":"46.3","Blood RNA - memory CD4 T-cell [nTPM]":"36.4","Blood RNA - memory CD8 T-cell [nTPM]":"37.2","Blood RNA - myeloid DC [nTPM]":"48.3","Blood RNA - naive B-cell [nTPM]":"36.4","Blood RNA - naive CD4 T-cell [nTPM]":"35.6","Blood RNA - naive CD8 T-cell [nTPM]":"36.1","Blood RNA - neutrophil [nTPM]":"17.9","Blood RNA - NK-cell [nTPM]":"45.5","Blood RNA - non-classical monocyte [nTPM]":"40.1","Blood RNA - plasmacytoid DC [nTPM]":"37.5","Blood RNA - T-reg [nTPM]":"46.3","Blood RNA - total PBMC [nTPM]":"42.0","Brain RNA - amygdala [nTPM]":"29.8","Brain RNA - basal ganglia [nTPM]":"30.8","Brain RNA - cerebellum [nTPM]":"33.7","Brain RNA - cerebral cortex [nTPM]":"36.8","Brain RNA - hippocampal formation [nTPM]":"28.7","Brain RNA - hypothalamus [nTPM]":"32.0","Brain RNA - medulla oblongata [nTPM]":"32.0","Brain RNA - midbrain [nTPM]":"31.4","Brain RNA - pons [nTPM]":"32.1","Brain RNA - spinal cord [nTPM]":"33.6","Brain RNA - thalamus [nTPM]":"31.0","Brain RNA - white matter [nTPM]":"33.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"19.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"7.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"3.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.3","Single Cell Type RNA - dendritic cells [nTPM]":"3.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"6.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.3","Single Cell Type RNA - Erythroid cells [nTPM]":"20.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.8","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"2.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.3","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"7.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.6","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"11.9","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"29.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.9","Single Cell Type RNA - Spermatocytes [nTPM]":"19.2","Single Cell Type RNA - Spermatogonia [nTPM]":"16.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.4","Single Cell Type RNA - T-cells [nTPM]":"13.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.9"},{"Gene":"DIAPH1","Gene synonym":["DFNA1","hDIA1","LFHL1"],"Ensembl":"ENSG00000131504","Gene description":"Diaphanous related formin 1","Uniprot":["O60610"],"Chromosome":"5","Position":"141515016-141619055","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":["Actin-binding"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Epilepsy","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"172.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"564.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004916","HPA076913"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA004916":"AB_1847668","HPA076913":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.81e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"27.9","Tissue RNA - adrenal gland [nTPM]":"20.3","Tissue RNA - amygdala [nTPM]":"21.0","Tissue RNA - appendix [nTPM]":"42.1","Tissue RNA - basal ganglia [nTPM]":"22.5","Tissue RNA - bone marrow [nTPM]":"90.2","Tissue RNA - breast [nTPM]":"24.2","Tissue RNA - cerebellum [nTPM]":"18.3","Tissue RNA - cerebral cortex [nTPM]":"20.9","Tissue RNA - cervix [nTPM]":"24.4","Tissue RNA - choroid plexus [nTPM]":"40.0","Tissue RNA - colon [nTPM]":"31.0","Tissue RNA - duodenum [nTPM]":"40.6","Tissue RNA - endometrium 1 [nTPM]":"18.5","Tissue RNA - epididymis [nTPM]":"44.3","Tissue RNA - esophagus [nTPM]":"58.0","Tissue RNA - fallopian tube [nTPM]":"25.2","Tissue RNA - gallbladder [nTPM]":"30.0","Tissue RNA - heart muscle [nTPM]":"34.9","Tissue RNA - hippocampal formation [nTPM]":"21.5","Tissue RNA - hypothalamus [nTPM]":"25.7","Tissue RNA - kidney [nTPM]":"38.1","Tissue RNA - liver [nTPM]":"91.7","Tissue RNA - lung [nTPM]":"51.3","Tissue RNA - lymph node [nTPM]":"67.0","Tissue RNA - medulla oblongata [nTPM]":"18.8","Tissue RNA - midbrain [nTPM]":"19.9","Tissue RNA - ovary [nTPM]":"12.9","Tissue RNA - pancreas [nTPM]":"37.3","Tissue RNA - parathyroid gland [nTPM]":"44.6","Tissue RNA - pituitary gland [nTPM]":"24.5","Tissue RNA - placenta [nTPM]":"25.1","Tissue RNA - pons [nTPM]":"20.1","Tissue RNA - prostate [nTPM]":"14.7","Tissue RNA - rectum [nTPM]":"31.1","Tissue RNA - retina [nTPM]":"28.4","Tissue RNA - salivary gland [nTPM]":"36.1","Tissue RNA - seminal vesicle [nTPM]":"19.3","Tissue RNA - skeletal muscle [nTPM]":"172.0","Tissue RNA - skin 1 [nTPM]":"47.3","Tissue RNA - small intestine [nTPM]":"36.5","Tissue RNA - smooth muscle [nTPM]":"18.7","Tissue RNA - spinal cord [nTPM]":"18.0","Tissue RNA - spleen [nTPM]":"36.3","Tissue RNA - stomach 1 [nTPM]":"45.1","Tissue RNA - testis [nTPM]":"19.9","Tissue RNA - thalamus [nTPM]":"27.4","Tissue RNA - thymus [nTPM]":"68.5","Tissue RNA - thyroid gland [nTPM]":"33.1","Tissue RNA - tongue [nTPM]":"55.7","Tissue RNA - tonsil [nTPM]":"66.4","Tissue RNA - urinary bladder [nTPM]":"47.1","Tissue RNA - vagina [nTPM]":"30.4","Tissue RNA - white matter [nTPM]":"18.6","Cell RNA - A-431 [nTPM]":"147.8","Cell RNA - A549 [nTPM]":"92.6","Cell RNA - AF22 [nTPM]":"53.2","Cell RNA - AN3-CA [nTPM]":"68.4","Cell RNA - ASC diff [nTPM]":"40.4","Cell RNA - ASC TERT1 [nTPM]":"54.5","Cell RNA - BEWO [nTPM]":"71.3","Cell RNA - BJ [nTPM]":"59.5","Cell RNA - BJ hTERT+ [nTPM]":"62.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"70.2","Cell RNA - CACO-2 [nTPM]":"318.1","Cell RNA - CAPAN-2 [nTPM]":"131.6","Cell RNA - Daudi [nTPM]":"156.5","Cell RNA - EFO-21 [nTPM]":"88.1","Cell RNA - fHDF\/TERT166 [nTPM]":"85.5","Cell RNA - GAMG [nTPM]":"103.0","Cell RNA - HaCaT [nTPM]":"157.9","Cell RNA - HAP1 [nTPM]":"116.9","Cell RNA - HBEC3-KT [nTPM]":"191.5","Cell RNA - HBF TERT88 [nTPM]":"84.8","Cell RNA - HDLM-2 [nTPM]":"88.9","Cell RNA - HEK 293 [nTPM]":"66.6","Cell RNA - HEL [nTPM]":"282.6","Cell RNA - HeLa [nTPM]":"121.4","Cell RNA - Hep G2 [nTPM]":"103.6","Cell RNA - HHSteC [nTPM]":"37.7","Cell RNA - HL-60 [nTPM]":"198.9","Cell RNA - HMC-1 [nTPM]":"564.7","Cell RNA - HSkMC [nTPM]":"34.4","Cell RNA - hTCEpi [nTPM]":"102.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"94.5","Cell RNA - hTERT-HME1 [nTPM]":"95.5","Cell RNA - hTERT-RPE1 [nTPM]":"30.5","Cell RNA - HUVEC TERT2 [nTPM]":"87.0","Cell RNA - JURKAT [nTPM]":"234.8","Cell RNA - K-562 [nTPM]":"101.2","Cell RNA - Karpas-707 [nTPM]":"106.9","Cell RNA - LHCN-M2 [nTPM]":"67.7","Cell RNA - MCF7 [nTPM]":"141.5","Cell RNA - MOLT-4 [nTPM]":"217.2","Cell RNA - NB-4 [nTPM]":"256.8","Cell RNA - NTERA-2 [nTPM]":"51.6","Cell RNA - OE19 [nTPM]":"75.2","Cell RNA - PC-3 [nTPM]":"61.6","Cell RNA - REH [nTPM]":"240.1","Cell RNA - RH-30 [nTPM]":"87.1","Cell RNA - RPMI-8226 [nTPM]":"87.6","Cell RNA - RPTEC TERT1 [nTPM]":"129.8","Cell RNA - RT4 [nTPM]":"158.5","Cell RNA - SCLC-21H [nTPM]":"69.4","Cell RNA - SH-SY5Y [nTPM]":"37.3","Cell RNA - SiHa [nTPM]":"146.2","Cell RNA - SK-BR-3 [nTPM]":"184.6","Cell RNA - SK-MEL-30 [nTPM]":"59.5","Cell RNA - SuSa [nTPM]":"47.5","Cell RNA - T-47d [nTPM]":"77.5","Cell RNA - THP-1 [nTPM]":"92.1","Cell RNA - TIME [nTPM]":"52.8","Cell RNA - U-138 MG [nTPM]":"93.9","Cell RNA - U-2 OS [nTPM]":"49.9","Cell RNA - U-2197 [nTPM]":"52.1","Cell RNA - U-251 MG [nTPM]":"119.9","Cell RNA - U-266\/70 [nTPM]":"54.2","Cell RNA - U-266\/84 [nTPM]":"94.4","Cell RNA - U-698 [nTPM]":"111.7","Cell RNA - U-87 MG [nTPM]":"50.2","Cell RNA - U-937 [nTPM]":"153.7","Cell RNA - WM-115 [nTPM]":"57.8","Blood RNA - basophil [nTPM]":"23.6","Blood RNA - classical monocyte [nTPM]":"12.8","Blood RNA - eosinophil [nTPM]":"29.8","Blood RNA - gdT-cell [nTPM]":"32.6","Blood RNA - intermediate monocyte [nTPM]":"14.0","Blood RNA - MAIT T-cell [nTPM]":"21.2","Blood RNA - memory B-cell [nTPM]":"9.3","Blood RNA - memory CD4 T-cell [nTPM]":"20.3","Blood RNA - memory CD8 T-cell [nTPM]":"25.3","Blood RNA - myeloid DC [nTPM]":"12.6","Blood RNA - naive B-cell [nTPM]":"9.1","Blood RNA - naive CD4 T-cell [nTPM]":"14.8","Blood RNA - naive CD8 T-cell [nTPM]":"23.9","Blood RNA - neutrophil [nTPM]":"13.7","Blood RNA - NK-cell [nTPM]":"13.7","Blood RNA - non-classical monocyte [nTPM]":"15.1","Blood RNA - plasmacytoid DC [nTPM]":"10.0","Blood RNA - T-reg [nTPM]":"18.7","Blood RNA - total PBMC [nTPM]":"15.4","Brain RNA - amygdala [nTPM]":"21.0","Brain RNA - basal ganglia [nTPM]":"22.5","Brain RNA - cerebellum [nTPM]":"18.3","Brain RNA - cerebral cortex [nTPM]":"20.9","Brain RNA - hippocampal formation [nTPM]":"21.5","Brain RNA - hypothalamus [nTPM]":"25.7","Brain RNA - medulla oblongata [nTPM]":"18.8","Brain RNA - midbrain [nTPM]":"19.9","Brain RNA - pons [nTPM]":"20.1","Brain RNA - spinal cord [nTPM]":"18.0","Brain RNA - thalamus [nTPM]":"27.4","Brain RNA - white matter [nTPM]":"18.6","Single Cell Type RNA - Adipocytes [nTPM]":"33.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"40.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"60.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"17.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"48.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.9","Single Cell Type RNA - dendritic cells [nTPM]":"96.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"60.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"62.7","Single Cell Type RNA - Early spermatids [nTPM]":"27.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.9","Single Cell Type RNA - Endothelial cells [nTPM]":"39.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"52.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"98.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.9","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"76.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"83.0","Single Cell Type RNA - granulocytes [nTPM]":"46.9","Single Cell Type RNA - Granulosa cells [nTPM]":"14.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"91.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.1","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.1","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"38.4","Single Cell Type RNA - Langerhans cells [nTPM]":"60.6","Single Cell Type RNA - Late spermatids [nTPM]":"9.0","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"78.5","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"54.6","Single Cell Type RNA - Muller glia cells [nTPM]":"12.1","Single Cell Type RNA - NK-cells [nTPM]":"115.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"122.9","Single Cell Type RNA - Paneth cells [nTPM]":"35.7","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"54.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"77.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.4","Single Cell Type RNA - Spermatocytes [nTPM]":"18.3","Single Cell Type RNA - Spermatogonia [nTPM]":"26.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.1","Single Cell Type RNA - T-cells [nTPM]":"92.8","Single Cell Type RNA - Theca cells [nTPM]":"18.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.1","Single Cell Type RNA - Urothelial cells [nTPM]":"91.2"},{"Gene":"DIAPH3","Gene synonym":["AN","AUNA1","DRF3","FLJ34705","NSDAN"],"Ensembl":"ENSG00000139734","Gene description":"Diaphanous related formin 3","Uniprot":["Q9NSV4"],"Chromosome":"13","Position":"59665583-60163928","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Deafness","Neuropathy","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"7.1","testis":"18.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"414.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032151"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane","Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA032151":"AB_2674181"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.04e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.18e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.72e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"7.1","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"18.9","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"5.4","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"47.7","Cell RNA - A549 [nTPM]":"15.6","Cell RNA - AF22 [nTPM]":"15.8","Cell RNA - AN3-CA [nTPM]":"9.1","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"7.1","Cell RNA - BEWO [nTPM]":"26.9","Cell RNA - BJ [nTPM]":"65.0","Cell RNA - BJ hTERT+ [nTPM]":"28.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.6","Cell RNA - CACO-2 [nTPM]":"41.7","Cell RNA - CAPAN-2 [nTPM]":"31.4","Cell RNA - Daudi [nTPM]":"15.9","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"33.4","Cell RNA - GAMG [nTPM]":"16.7","Cell RNA - HaCaT [nTPM]":"31.7","Cell RNA - HAP1 [nTPM]":"26.0","Cell RNA - HBEC3-KT [nTPM]":"25.5","Cell RNA - HBF TERT88 [nTPM]":"96.9","Cell RNA - HDLM-2 [nTPM]":"18.0","Cell RNA - HEK 293 [nTPM]":"17.9","Cell RNA - HEL [nTPM]":"22.7","Cell RNA - HeLa [nTPM]":"37.6","Cell RNA - Hep G2 [nTPM]":"9.5","Cell RNA - HHSteC [nTPM]":"4.1","Cell RNA - HL-60 [nTPM]":"31.2","Cell RNA - HMC-1 [nTPM]":"17.4","Cell RNA - HSkMC [nTPM]":"2.8","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.2","Cell RNA - hTERT-HME1 [nTPM]":"26.3","Cell RNA - hTERT-RPE1 [nTPM]":"16.3","Cell RNA - HUVEC TERT2 [nTPM]":"29.2","Cell RNA - JURKAT [nTPM]":"14.0","Cell RNA - K-562 [nTPM]":"17.8","Cell RNA - Karpas-707 [nTPM]":"21.9","Cell RNA - LHCN-M2 [nTPM]":"61.8","Cell RNA - MCF7 [nTPM]":"6.9","Cell RNA - MOLT-4 [nTPM]":"28.0","Cell RNA - NB-4 [nTPM]":"10.2","Cell RNA - NTERA-2 [nTPM]":"14.7","Cell RNA - OE19 [nTPM]":"22.5","Cell RNA - PC-3 [nTPM]":"8.9","Cell RNA - REH [nTPM]":"18.8","Cell RNA - RH-30 [nTPM]":"38.9","Cell RNA - RPMI-8226 [nTPM]":"12.9","Cell RNA - RPTEC TERT1 [nTPM]":"19.9","Cell RNA - RT4 [nTPM]":"9.6","Cell RNA - SCLC-21H [nTPM]":"8.3","Cell RNA - SH-SY5Y [nTPM]":"14.3","Cell RNA - SiHa [nTPM]":"33.2","Cell RNA - SK-BR-3 [nTPM]":"22.8","Cell RNA - SK-MEL-30 [nTPM]":"9.5","Cell RNA - SuSa [nTPM]":"33.8","Cell RNA - T-47d [nTPM]":"16.7","Cell RNA - THP-1 [nTPM]":"16.8","Cell RNA - TIME [nTPM]":"29.3","Cell RNA - U-138 MG [nTPM]":"40.5","Cell RNA - U-2 OS [nTPM]":"25.9","Cell RNA - U-2197 [nTPM]":"13.7","Cell RNA - U-251 MG [nTPM]":"54.5","Cell RNA - U-266\/70 [nTPM]":"14.7","Cell RNA - U-266\/84 [nTPM]":"17.1","Cell RNA - U-698 [nTPM]":"24.4","Cell RNA - U-87 MG [nTPM]":"10.9","Cell RNA - U-937 [nTPM]":"15.2","Cell RNA - WM-115 [nTPM]":"31.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"39.8","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"414.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"26.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.7","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"78.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"56.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"18.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.9","Single Cell Type RNA - Spermatocytes [nTPM]":"39.2","Single Cell Type RNA - Spermatogonia [nTPM]":"17.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"2.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"DMXL2","Gene synonym":["DFNA71","KIAA0856","RC3"],"Ensembl":"ENSG00000104093","Gene description":"Dmx like 2","Uniprot":["Q8TDJ6"],"Chromosome":"15","Position":"51447711-51622833","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Diabetes mellitus","Disease variant","Epilepsy","Hypogonadotropic hypogonadism","Neuropathy","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"138.9","Inhibitory neurons":"122.9","Kupffer cells":"96.1","Macrophages":"106.3","monocytes":"84.9","Oligodendrocyte precursor cells":"96.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"2.8","intermediate monocyte":"2.2","neutrophil":"2.2","non-classical monocyte":"2.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.2","monocytes":"2.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-937":"44.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039375"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039375":"AB_10673610"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"4.7","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"11.1","Tissue RNA - basal ganglia [nTPM]":"4.7","Tissue RNA - bone marrow [nTPM]":"17.1","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"4.6","Tissue RNA - choroid plexus [nTPM]":"8.1","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"13.9","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"3.1","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"4.1","Tissue RNA - pancreas [nTPM]":"5.4","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"7.5","Tissue RNA - retina [nTPM]":"16.3","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"7.1","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"9.0","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"6.0","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"9.1","Cell RNA - A549 [nTPM]":"11.7","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"7.3","Cell RNA - ASC diff [nTPM]":"5.3","Cell RNA - ASC TERT1 [nTPM]":"9.1","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"6.9","Cell RNA - BJ hTERT+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.5","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"4.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"4.1","Cell RNA - GAMG [nTPM]":"12.5","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"4.8","Cell RNA - HBF TERT88 [nTPM]":"8.7","Cell RNA - HDLM-2 [nTPM]":"10.6","Cell RNA - HEK 293 [nTPM]":"3.9","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"20.6","Cell RNA - HMC-1 [nTPM]":"5.8","Cell RNA - HSkMC [nTPM]":"4.2","Cell RNA - hTCEpi [nTPM]":"3.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.4","Cell RNA - hTERT-HME1 [nTPM]":"3.7","Cell RNA - hTERT-RPE1 [nTPM]":"6.8","Cell RNA - HUVEC TERT2 [nTPM]":"4.5","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"8.3","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"6.7","Cell RNA - MCF7 [nTPM]":"10.0","Cell RNA - MOLT-4 [nTPM]":"8.9","Cell RNA - NB-4 [nTPM]":"19.2","Cell RNA - NTERA-2 [nTPM]":"9.2","Cell RNA - OE19 [nTPM]":"4.3","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"7.9","Cell RNA - RH-30 [nTPM]":"10.3","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"3.4","Cell RNA - RT4 [nTPM]":"18.1","Cell RNA - SCLC-21H [nTPM]":"18.0","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"7.3","Cell RNA - SK-BR-3 [nTPM]":"4.1","Cell RNA - SK-MEL-30 [nTPM]":"8.5","Cell RNA - SuSa [nTPM]":"11.0","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"21.9","Cell RNA - TIME [nTPM]":"5.7","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"11.0","Cell RNA - U-251 MG [nTPM]":"8.2","Cell RNA - U-266\/70 [nTPM]":"16.0","Cell RNA - U-266\/84 [nTPM]":"25.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"9.2","Cell RNA - U-937 [nTPM]":"44.0","Cell RNA - WM-115 [nTPM]":"7.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.7","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"5.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.7","Single Cell Type RNA - Astrocytes [nTPM]":"68.6","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"41.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"6.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - dendritic cells [nTPM]":"13.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"138.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.9","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.5","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"10.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"6.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.5","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"122.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"96.1","Single Cell Type RNA - Langerhans cells [nTPM]":"16.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"106.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"84.9","Single Cell Type RNA - Muller glia cells [nTPM]":"8.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"96.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"50.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.7","Single Cell Type RNA - Spermatocytes [nTPM]":"37.2","Single Cell Type RNA - Spermatogonia [nTPM]":"30.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"9.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.9","Single Cell Type RNA - Urothelial cells [nTPM]":"2.7"},{"Gene":"DNA2","Gene synonym":["DNA2L","KIAA0083"],"Ensembl":"ENSG00000138346","Gene description":"DNA replication helicase\/nuclease 2","Uniprot":["P51530"],"Chromosome":"10","Position":"68414064-68472121","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","DNA replication"],"Molecular function":["DNA-binding","Endonuclease","Helicase","Hydrolase","Multifunctional enzyme","Nuclease"],"Disease involvement":["Disease variant","Dwarfism","Mental retardation","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"8.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"33.2","Excitatory neurons":"14.1","Inhibitory neurons":"15.5","Oligodendrocytes":"18.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"NK-cell":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"NK-cells":"1.8"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037487","HPA057526"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA037487":"AB_10672493","HPA057526":"AB_2683456"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"3.6","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"2.6","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"5.2","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"25.6","Cell RNA - A549 [nTPM]":"13.0","Cell RNA - AF22 [nTPM]":"29.0","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"3.2","Cell RNA - ASC TERT1 [nTPM]":"2.2","Cell RNA - BEWO [nTPM]":"20.4","Cell RNA - BJ [nTPM]":"12.4","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.2","Cell RNA - CACO-2 [nTPM]":"31.1","Cell RNA - CAPAN-2 [nTPM]":"16.1","Cell RNA - Daudi [nTPM]":"26.1","Cell RNA - EFO-21 [nTPM]":"4.6","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"6.7","Cell RNA - HaCaT [nTPM]":"15.2","Cell RNA - HAP1 [nTPM]":"16.8","Cell RNA - HBEC3-KT [nTPM]":"6.5","Cell RNA - HBF TERT88 [nTPM]":"20.7","Cell RNA - HDLM-2 [nTPM]":"16.2","Cell RNA - HEK 293 [nTPM]":"12.6","Cell RNA - HEL [nTPM]":"15.8","Cell RNA - HeLa [nTPM]":"8.5","Cell RNA - Hep G2 [nTPM]":"12.3","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"16.4","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.3","Cell RNA - hTERT-HME1 [nTPM]":"3.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.5","Cell RNA - HUVEC TERT2 [nTPM]":"7.9","Cell RNA - JURKAT [nTPM]":"17.0","Cell RNA - K-562 [nTPM]":"23.6","Cell RNA - Karpas-707 [nTPM]":"22.8","Cell RNA - LHCN-M2 [nTPM]":"10.1","Cell RNA - MCF7 [nTPM]":"9.0","Cell RNA - MOLT-4 [nTPM]":"42.8","Cell RNA - NB-4 [nTPM]":"19.8","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"10.9","Cell RNA - PC-3 [nTPM]":"24.0","Cell RNA - REH [nTPM]":"33.1","Cell RNA - RH-30 [nTPM]":"20.0","Cell RNA - RPMI-8226 [nTPM]":"8.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.5","Cell RNA - RT4 [nTPM]":"11.7","Cell RNA - SCLC-21H [nTPM]":"13.1","Cell RNA - SH-SY5Y [nTPM]":"15.7","Cell RNA - SiHa [nTPM]":"16.9","Cell RNA - SK-BR-3 [nTPM]":"21.4","Cell RNA - SK-MEL-30 [nTPM]":"4.2","Cell RNA - SuSa [nTPM]":"20.1","Cell RNA - T-47d [nTPM]":"16.5","Cell RNA - THP-1 [nTPM]":"11.6","Cell RNA - TIME [nTPM]":"3.4","Cell RNA - U-138 MG [nTPM]":"6.6","Cell RNA - U-2 OS [nTPM]":"20.5","Cell RNA - U-2197 [nTPM]":"8.5","Cell RNA - U-251 MG [nTPM]":"23.8","Cell RNA - U-266\/70 [nTPM]":"11.5","Cell RNA - U-266\/84 [nTPM]":"13.9","Cell RNA - U-698 [nTPM]":"38.3","Cell RNA - U-87 MG [nTPM]":"5.7","Cell RNA - U-937 [nTPM]":"26.1","Cell RNA - WM-115 [nTPM]":"8.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"3.6","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"33.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.8","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"4.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"7.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"9.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"DNAJB2","Gene synonym":["CMT2T","HSJ1","HSPF3"],"Ensembl":"ENSG00000135924","Gene description":"DnaJ heat shock protein family (Hsp40) member B2","Uniprot":["P25686"],"Chromosome":"2","Position":"219279342-219286898","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"366.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036268"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9900","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA036268":"AB_10670793"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-3"},"Tissue RNA - adipose tissue [nTPM]":"41.9","Tissue RNA - adrenal gland [nTPM]":"106.9","Tissue RNA - amygdala [nTPM]":"264.5","Tissue RNA - appendix [nTPM]":"17.7","Tissue RNA - basal ganglia [nTPM]":"290.6","Tissue RNA - bone marrow [nTPM]":"26.6","Tissue RNA - breast [nTPM]":"45.7","Tissue RNA - cerebellum [nTPM]":"276.0","Tissue RNA - cerebral cortex [nTPM]":"323.5","Tissue RNA - cervix [nTPM]":"63.8","Tissue RNA - choroid plexus [nTPM]":"232.0","Tissue RNA - colon [nTPM]":"48.9","Tissue RNA - duodenum [nTPM]":"23.2","Tissue RNA - endometrium 1 [nTPM]":"46.2","Tissue RNA - epididymis [nTPM]":"45.2","Tissue RNA - esophagus [nTPM]":"54.1","Tissue RNA - fallopian tube [nTPM]":"48.2","Tissue RNA - gallbladder [nTPM]":"26.6","Tissue RNA - heart muscle [nTPM]":"85.4","Tissue RNA - hippocampal formation [nTPM]":"266.6","Tissue RNA - hypothalamus [nTPM]":"270.7","Tissue RNA - kidney [nTPM]":"81.0","Tissue RNA - liver [nTPM]":"72.1","Tissue RNA - lung [nTPM]":"45.8","Tissue RNA - lymph node [nTPM]":"26.0","Tissue RNA - medulla oblongata [nTPM]":"281.8","Tissue RNA - midbrain [nTPM]":"281.8","Tissue RNA - ovary [nTPM]":"65.0","Tissue RNA - pancreas [nTPM]":"84.8","Tissue RNA - parathyroid gland [nTPM]":"54.3","Tissue RNA - pituitary gland [nTPM]":"112.1","Tissue RNA - placenta [nTPM]":"27.1","Tissue RNA - pons [nTPM]":"279.7","Tissue RNA - prostate [nTPM]":"73.9","Tissue RNA - rectum [nTPM]":"15.8","Tissue RNA - retina [nTPM]":"63.9","Tissue RNA - salivary gland [nTPM]":"62.3","Tissue RNA - seminal vesicle [nTPM]":"35.5","Tissue RNA - skeletal muscle [nTPM]":"135.6","Tissue RNA - skin 1 [nTPM]":"108.1","Tissue RNA - small intestine [nTPM]":"36.0","Tissue RNA - smooth muscle [nTPM]":"15.8","Tissue RNA - spinal cord [nTPM]":"269.7","Tissue RNA - spleen [nTPM]":"46.7","Tissue RNA - stomach 1 [nTPM]":"54.8","Tissue RNA - testis [nTPM]":"86.0","Tissue RNA - thalamus [nTPM]":"280.5","Tissue RNA - thymus [nTPM]":"28.4","Tissue RNA - thyroid gland [nTPM]":"71.0","Tissue RNA - tongue [nTPM]":"56.5","Tissue RNA - tonsil [nTPM]":"20.5","Tissue RNA - urinary bladder [nTPM]":"52.8","Tissue RNA - vagina [nTPM]":"59.0","Tissue RNA - white matter [nTPM]":"366.0","Cell RNA - A-431 [nTPM]":"34.9","Cell RNA - A549 [nTPM]":"14.2","Cell RNA - AF22 [nTPM]":"21.9","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"45.6","Cell RNA - ASC TERT1 [nTPM]":"22.1","Cell RNA - BEWO [nTPM]":"29.3","Cell RNA - BJ [nTPM]":"32.8","Cell RNA - BJ hTERT+ [nTPM]":"27.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.2","Cell RNA - CACO-2 [nTPM]":"66.2","Cell RNA - CAPAN-2 [nTPM]":"21.3","Cell RNA - Daudi [nTPM]":"21.4","Cell RNA - EFO-21 [nTPM]":"39.7","Cell RNA - fHDF\/TERT166 [nTPM]":"31.6","Cell RNA - GAMG [nTPM]":"66.3","Cell RNA - HaCaT [nTPM]":"49.1","Cell RNA - HAP1 [nTPM]":"27.9","Cell RNA - HBEC3-KT [nTPM]":"36.3","Cell RNA - HBF TERT88 [nTPM]":"16.3","Cell RNA - HDLM-2 [nTPM]":"45.3","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"41.7","Cell RNA - HeLa [nTPM]":"28.0","Cell RNA - Hep G2 [nTPM]":"32.0","Cell RNA - HHSteC [nTPM]":"30.8","Cell RNA - HL-60 [nTPM]":"7.1","Cell RNA - HMC-1 [nTPM]":"36.5","Cell RNA - HSkMC [nTPM]":"21.3","Cell RNA - hTCEpi [nTPM]":"103.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.8","Cell RNA - hTERT-HME1 [nTPM]":"38.4","Cell RNA - hTERT-RPE1 [nTPM]":"51.3","Cell RNA - HUVEC TERT2 [nTPM]":"12.9","Cell RNA - JURKAT [nTPM]":"23.5","Cell RNA - K-562 [nTPM]":"7.4","Cell RNA - Karpas-707 [nTPM]":"23.7","Cell RNA - LHCN-M2 [nTPM]":"21.4","Cell RNA - MCF7 [nTPM]":"18.0","Cell RNA - MOLT-4 [nTPM]":"13.0","Cell RNA - NB-4 [nTPM]":"8.4","Cell RNA - NTERA-2 [nTPM]":"12.9","Cell RNA - OE19 [nTPM]":"30.2","Cell RNA - PC-3 [nTPM]":"26.4","Cell RNA - REH [nTPM]":"13.4","Cell RNA - RH-30 [nTPM]":"17.9","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"31.7","Cell RNA - RT4 [nTPM]":"24.5","Cell RNA - SCLC-21H [nTPM]":"20.6","Cell RNA - SH-SY5Y [nTPM]":"26.0","Cell RNA - SiHa [nTPM]":"38.0","Cell RNA - SK-BR-3 [nTPM]":"38.4","Cell RNA - SK-MEL-30 [nTPM]":"64.9","Cell RNA - SuSa [nTPM]":"57.5","Cell RNA - T-47d [nTPM]":"28.6","Cell RNA - THP-1 [nTPM]":"14.9","Cell RNA - TIME [nTPM]":"17.5","Cell RNA - U-138 MG [nTPM]":"41.6","Cell RNA - U-2 OS [nTPM]":"82.3","Cell RNA - U-2197 [nTPM]":"12.0","Cell RNA - U-251 MG [nTPM]":"28.6","Cell RNA - U-266\/70 [nTPM]":"26.2","Cell RNA - U-266\/84 [nTPM]":"8.4","Cell RNA - U-698 [nTPM]":"35.0","Cell RNA - U-87 MG [nTPM]":"42.8","Cell RNA - U-937 [nTPM]":"6.5","Cell RNA - WM-115 [nTPM]":"31.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"264.5","Brain RNA - basal ganglia [nTPM]":"290.6","Brain RNA - cerebellum [nTPM]":"276.0","Brain RNA - cerebral cortex [nTPM]":"323.5","Brain RNA - hippocampal formation [nTPM]":"266.6","Brain RNA - hypothalamus [nTPM]":"270.7","Brain RNA - medulla oblongata [nTPM]":"281.8","Brain RNA - midbrain [nTPM]":"281.8","Brain RNA - pons [nTPM]":"279.7","Brain RNA - spinal cord [nTPM]":"269.7","Brain RNA - thalamus [nTPM]":"280.5","Brain RNA - white matter [nTPM]":"366.0","Single Cell Type RNA - Adipocytes [nTPM]":"24.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.4","Single Cell Type RNA - Astrocytes [nTPM]":"35.6","Single Cell Type RNA - B-cells [nTPM]":"30.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"97.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"61.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"77.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"18.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.1","Single Cell Type RNA - dendritic cells [nTPM]":"24.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"78.2","Single Cell Type RNA - Ductal cells [nTPM]":"60.0","Single Cell Type RNA - Early spermatids [nTPM]":"43.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.2","Single Cell Type RNA - Endothelial cells [nTPM]":"22.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"53.7","Single Cell Type RNA - Erythroid cells [nTPM]":"69.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.7","Single Cell Type RNA - Fibroblasts [nTPM]":"27.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.9","Single Cell Type RNA - granulocytes [nTPM]":"24.8","Single Cell Type RNA - Granulosa cells [nTPM]":"22.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"20.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.2","Single Cell Type RNA - Horizontal cells [nTPM]":"80.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"47.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.7","Single Cell Type RNA - Langerhans cells [nTPM]":"28.2","Single Cell Type RNA - Late spermatids [nTPM]":"70.9","Single Cell Type RNA - Leydig cells [nTPM]":"36.4","Single Cell Type RNA - Macrophages [nTPM]":"28.0","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"21.6","Single Cell Type RNA - Muller glia cells [nTPM]":"84.8","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"144.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"68.9","Single Cell Type RNA - Paneth cells [nTPM]":"23.6","Single Cell Type RNA - Peritubular cells [nTPM]":"39.1","Single Cell Type RNA - Plasma cells [nTPM]":"28.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"56.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"87.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.3","Single Cell Type RNA - Spermatocytes [nTPM]":"56.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"69.0","Single Cell Type RNA - T-cells [nTPM]":"30.2","Single Cell Type RNA - Theca cells [nTPM]":"23.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.5","Single Cell Type RNA - Urothelial cells [nTPM]":"25.8"},{"Gene":"DNAJC13","Gene synonym":["KIAA0678","RME8"],"Ensembl":"ENSG00000138246","Gene description":"DnaJ heat shock protein family (Hsp40) member C13","Uniprot":["O75165"],"Chromosome":"3","Position":"132417502-132539032","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Chaperone"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036923","HPA036924"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA036923":"AB_10672480","HPA036924":"AB_2675386"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"9.4","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"12.4","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"15.5","Tissue RNA - breast [nTPM]":"11.4","Tissue RNA - cerebellum [nTPM]":"6.0","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"8.2","Tissue RNA - colon [nTPM]":"14.4","Tissue RNA - duodenum [nTPM]":"10.9","Tissue RNA - endometrium 1 [nTPM]":"13.8","Tissue RNA - epididymis [nTPM]":"11.7","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"9.9","Tissue RNA - gallbladder [nTPM]":"9.9","Tissue RNA - heart muscle [nTPM]":"12.9","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"16.0","Tissue RNA - liver [nTPM]":"9.8","Tissue RNA - lung [nTPM]":"11.3","Tissue RNA - lymph node [nTPM]":"11.0","Tissue RNA - medulla oblongata [nTPM]":"7.7","Tissue RNA - midbrain [nTPM]":"6.9","Tissue RNA - ovary [nTPM]":"11.7","Tissue RNA - pancreas [nTPM]":"6.8","Tissue RNA - parathyroid gland [nTPM]":"12.6","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"15.4","Tissue RNA - pons [nTPM]":"7.1","Tissue RNA - prostate [nTPM]":"10.8","Tissue RNA - rectum [nTPM]":"14.3","Tissue RNA - retina [nTPM]":"10.7","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"12.1","Tissue RNA - skeletal muscle [nTPM]":"12.5","Tissue RNA - skin 1 [nTPM]":"9.8","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"16.7","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"12.2","Tissue RNA - stomach 1 [nTPM]":"9.7","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"7.5","Tissue RNA - thymus [nTPM]":"12.0","Tissue RNA - thyroid gland [nTPM]":"15.7","Tissue RNA - tongue [nTPM]":"14.2","Tissue RNA - tonsil [nTPM]":"10.6","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"7.8","Cell RNA - A-431 [nTPM]":"31.0","Cell RNA - A549 [nTPM]":"18.0","Cell RNA - AF22 [nTPM]":"22.2","Cell RNA - AN3-CA [nTPM]":"10.9","Cell RNA - ASC diff [nTPM]":"54.3","Cell RNA - ASC TERT1 [nTPM]":"46.7","Cell RNA - BEWO [nTPM]":"13.7","Cell RNA - BJ [nTPM]":"32.3","Cell RNA - BJ hTERT+ [nTPM]":"62.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.8","Cell RNA - CACO-2 [nTPM]":"20.4","Cell RNA - CAPAN-2 [nTPM]":"18.2","Cell RNA - Daudi [nTPM]":"15.7","Cell RNA - EFO-21 [nTPM]":"20.5","Cell RNA - fHDF\/TERT166 [nTPM]":"46.3","Cell RNA - GAMG [nTPM]":"41.1","Cell RNA - HaCaT [nTPM]":"24.1","Cell RNA - HAP1 [nTPM]":"22.1","Cell RNA - HBEC3-KT [nTPM]":"24.3","Cell RNA - HBF TERT88 [nTPM]":"43.5","Cell RNA - HDLM-2 [nTPM]":"18.3","Cell RNA - HEK 293 [nTPM]":"6.4","Cell RNA - HEL [nTPM]":"20.6","Cell RNA - HeLa [nTPM]":"17.1","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"27.6","Cell RNA - HL-60 [nTPM]":"21.1","Cell RNA - HMC-1 [nTPM]":"18.3","Cell RNA - HSkMC [nTPM]":"34.2","Cell RNA - hTCEpi [nTPM]":"16.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.5","Cell RNA - hTERT-HME1 [nTPM]":"35.1","Cell RNA - hTERT-RPE1 [nTPM]":"22.7","Cell RNA - HUVEC TERT2 [nTPM]":"44.6","Cell RNA - JURKAT [nTPM]":"26.0","Cell RNA - K-562 [nTPM]":"11.4","Cell RNA - Karpas-707 [nTPM]":"25.6","Cell RNA - LHCN-M2 [nTPM]":"43.7","Cell RNA - MCF7 [nTPM]":"24.1","Cell RNA - MOLT-4 [nTPM]":"16.8","Cell RNA - NB-4 [nTPM]":"9.1","Cell RNA - NTERA-2 [nTPM]":"12.7","Cell RNA - OE19 [nTPM]":"26.7","Cell RNA - PC-3 [nTPM]":"15.8","Cell RNA - REH [nTPM]":"15.9","Cell RNA - RH-30 [nTPM]":"16.5","Cell RNA - RPMI-8226 [nTPM]":"13.0","Cell RNA - RPTEC TERT1 [nTPM]":"27.7","Cell RNA - RT4 [nTPM]":"32.4","Cell RNA - SCLC-21H [nTPM]":"7.9","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"31.6","Cell RNA - SK-BR-3 [nTPM]":"16.7","Cell RNA - SK-MEL-30 [nTPM]":"36.1","Cell RNA - SuSa [nTPM]":"19.0","Cell RNA - T-47d [nTPM]":"24.7","Cell RNA - THP-1 [nTPM]":"17.8","Cell RNA - TIME [nTPM]":"40.9","Cell RNA - U-138 MG [nTPM]":"34.7","Cell RNA - U-2 OS [nTPM]":"17.8","Cell RNA - U-2197 [nTPM]":"33.3","Cell RNA - U-251 MG [nTPM]":"13.9","Cell RNA - U-266\/70 [nTPM]":"14.8","Cell RNA - U-266\/84 [nTPM]":"15.7","Cell RNA - U-698 [nTPM]":"21.5","Cell RNA - U-87 MG [nTPM]":"36.8","Cell RNA - U-937 [nTPM]":"13.6","Cell RNA - WM-115 [nTPM]":"25.2","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"4.0","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"6.0","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"7.7","Brain RNA - midbrain [nTPM]":"6.9","Brain RNA - pons [nTPM]":"7.1","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"7.5","Brain RNA - white matter [nTPM]":"7.8","Single Cell Type RNA - Adipocytes [nTPM]":"16.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.9","Single Cell Type RNA - Astrocytes [nTPM]":"45.7","Single Cell Type RNA - B-cells [nTPM]":"14.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"10.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"47.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"11.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.9","Single Cell Type RNA - dendritic cells [nTPM]":"13.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.3","Single Cell Type RNA - Endothelial cells [nTPM]":"17.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"20.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.7","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"18.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.5","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"34.2","Single Cell Type RNA - Langerhans cells [nTPM]":"9.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"26.5","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"60.0","Single Cell Type RNA - monocytes [nTPM]":"25.1","Single Cell Type RNA - Muller glia cells [nTPM]":"13.3","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"46.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"64.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"12.5","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.7","Single Cell Type RNA - Spermatocytes [nTPM]":"5.3","Single Cell Type RNA - Spermatogonia [nTPM]":"13.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"10.8","Single Cell Type RNA - Theca cells [nTPM]":"22.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.4","Single Cell Type RNA - Urothelial cells [nTPM]":"11.0"},{"Gene":"DNAJC16","Gene synonym":["KIAA0962"],"Ensembl":"ENSG00000116138","Gene description":"DnaJ heat shock protein family (Hsp40) member C16","Uniprot":["Q9Y2G8"],"Chromosome":"1","Position":"15526813-15592379","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043643"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA043643":"AB_10796794"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.77e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"4.5","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"5.3","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"5.4","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"7.8","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"6.8","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"11.5","Tissue RNA - liver [nTPM]":"10.1","Tissue RNA - lung [nTPM]":"4.8","Tissue RNA - lymph node [nTPM]":"6.2","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"10.0","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"4.8","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"9.0","Tissue RNA - salivary gland [nTPM]":"7.0","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"11.9","Tissue RNA - skin 1 [nTPM]":"5.6","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"6.3","Tissue RNA - thalamus [nTPM]":"5.0","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"7.4","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"6.4","Tissue RNA - urinary bladder [nTPM]":"5.2","Tissue RNA - vagina [nTPM]":"4.6","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"8.8","Cell RNA - A549 [nTPM]":"8.7","Cell RNA - AF22 [nTPM]":"6.7","Cell RNA - AN3-CA [nTPM]":"12.4","Cell RNA - ASC diff [nTPM]":"18.0","Cell RNA - ASC TERT1 [nTPM]":"14.5","Cell RNA - BEWO [nTPM]":"6.3","Cell RNA - BJ [nTPM]":"10.4","Cell RNA - BJ hTERT+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.9","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"12.7","Cell RNA - Daudi [nTPM]":"7.6","Cell RNA - EFO-21 [nTPM]":"6.8","Cell RNA - fHDF\/TERT166 [nTPM]":"10.3","Cell RNA - GAMG [nTPM]":"13.3","Cell RNA - HaCaT [nTPM]":"10.7","Cell RNA - HAP1 [nTPM]":"8.3","Cell RNA - HBEC3-KT [nTPM]":"9.2","Cell RNA - HBF TERT88 [nTPM]":"14.3","Cell RNA - HDLM-2 [nTPM]":"9.0","Cell RNA - HEK 293 [nTPM]":"4.0","Cell RNA - HEL [nTPM]":"7.8","Cell RNA - HeLa [nTPM]":"9.6","Cell RNA - Hep G2 [nTPM]":"12.2","Cell RNA - HHSteC [nTPM]":"17.8","Cell RNA - HL-60 [nTPM]":"12.2","Cell RNA - HMC-1 [nTPM]":"8.7","Cell RNA - HSkMC [nTPM]":"10.5","Cell RNA - hTCEpi [nTPM]":"10.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.4","Cell RNA - hTERT-HME1 [nTPM]":"9.2","Cell RNA - hTERT-RPE1 [nTPM]":"12.7","Cell RNA - HUVEC TERT2 [nTPM]":"11.6","Cell RNA - JURKAT [nTPM]":"6.3","Cell RNA - K-562 [nTPM]":"16.9","Cell RNA - Karpas-707 [nTPM]":"6.7","Cell RNA - LHCN-M2 [nTPM]":"11.8","Cell RNA - MCF7 [nTPM]":"3.6","Cell RNA - MOLT-4 [nTPM]":"6.2","Cell RNA - NB-4 [nTPM]":"6.2","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"7.9","Cell RNA - PC-3 [nTPM]":"5.6","Cell RNA - REH [nTPM]":"7.3","Cell RNA - RH-30 [nTPM]":"8.6","Cell RNA - RPMI-8226 [nTPM]":"8.5","Cell RNA - RPTEC TERT1 [nTPM]":"12.6","Cell RNA - RT4 [nTPM]":"6.0","Cell RNA - SCLC-21H [nTPM]":"7.5","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"10.6","Cell RNA - SK-BR-3 [nTPM]":"10.1","Cell RNA - SK-MEL-30 [nTPM]":"9.0","Cell RNA - SuSa [nTPM]":"9.6","Cell RNA - T-47d [nTPM]":"6.3","Cell RNA - THP-1 [nTPM]":"4.8","Cell RNA - TIME [nTPM]":"15.7","Cell RNA - U-138 MG [nTPM]":"17.9","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"16.7","Cell RNA - U-251 MG [nTPM]":"5.7","Cell RNA - U-266\/70 [nTPM]":"9.1","Cell RNA - U-266\/84 [nTPM]":"13.8","Cell RNA - U-698 [nTPM]":"6.6","Cell RNA - U-87 MG [nTPM]":"11.1","Cell RNA - U-937 [nTPM]":"6.9","Cell RNA - WM-115 [nTPM]":"8.7","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"3.9","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"4.5","Brain RNA - basal ganglia [nTPM]":"5.3","Brain RNA - cerebellum [nTPM]":"5.4","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"4.8","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"5.0","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"11.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.7","Single Cell Type RNA - Astrocytes [nTPM]":"25.5","Single Cell Type RNA - B-cells [nTPM]":"12.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"14.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"14.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.8","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.1","Single Cell Type RNA - Early spermatids [nTPM]":"11.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.0","Single Cell Type RNA - Endothelial cells [nTPM]":"12.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.6","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"14.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"20.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.9","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"20.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"5.8","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"9.5","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"11.4","Single Cell Type RNA - Muller glia cells [nTPM]":"12.8","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.5","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"6.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.8","Single Cell Type RNA - Spermatocytes [nTPM]":"24.7","Single Cell Type RNA - Spermatogonia [nTPM]":"15.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.0","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8.2"},{"Gene":"DNAJC3","Gene synonym":["ERdj6","HP58","P58","p58(IPK)","P58IPK","PRKRI"],"Ensembl":"ENSG00000102580","Gene description":"DnaJ heat shock protein family (Hsp40) member C3","Uniprot":["Q13217"],"Chromosome":"13","Position":"95677139-95794988","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Stress response","Translation regulation","Unfolded protein response"],"Molecular function":["Chaperone","Repressor"],"Disease involvement":["Deafness","Diabetes mellitus","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039336","HPA041326"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4900000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA039336":"AB_2676451","HPA041326":"AB_2677412"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.47e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.0","Tissue RNA - adrenal gland [nTPM]":"20.0","Tissue RNA - amygdala [nTPM]":"10.7","Tissue RNA - appendix [nTPM]":"22.5","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"45.6","Tissue RNA - breast [nTPM]":"21.3","Tissue RNA - cerebellum [nTPM]":"13.0","Tissue RNA - cerebral cortex [nTPM]":"11.4","Tissue RNA - cervix [nTPM]":"35.1","Tissue RNA - choroid plexus [nTPM]":"22.3","Tissue RNA - colon [nTPM]":"25.2","Tissue RNA - duodenum [nTPM]":"23.8","Tissue RNA - endometrium 1 [nTPM]":"20.4","Tissue RNA - epididymis [nTPM]":"38.9","Tissue RNA - esophagus [nTPM]":"15.9","Tissue RNA - fallopian tube [nTPM]":"20.4","Tissue RNA - gallbladder [nTPM]":"22.0","Tissue RNA - heart muscle [nTPM]":"16.6","Tissue RNA - hippocampal formation [nTPM]":"10.0","Tissue RNA - hypothalamus [nTPM]":"14.1","Tissue RNA - kidney [nTPM]":"25.5","Tissue RNA - liver [nTPM]":"41.8","Tissue RNA - lung [nTPM]":"22.9","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"15.1","Tissue RNA - midbrain [nTPM]":"12.5","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"36.0","Tissue RNA - parathyroid gland [nTPM]":"24.4","Tissue RNA - pituitary gland [nTPM]":"16.2","Tissue RNA - placenta [nTPM]":"24.7","Tissue RNA - pons [nTPM]":"15.5","Tissue RNA - prostate [nTPM]":"34.5","Tissue RNA - rectum [nTPM]":"26.4","Tissue RNA - retina [nTPM]":"9.9","Tissue RNA - salivary gland [nTPM]":"36.3","Tissue RNA - seminal vesicle [nTPM]":"26.0","Tissue RNA - skeletal muscle [nTPM]":"9.3","Tissue RNA - skin 1 [nTPM]":"10.9","Tissue RNA - small intestine [nTPM]":"24.0","Tissue RNA - smooth muscle [nTPM]":"22.3","Tissue RNA - spinal cord [nTPM]":"13.4","Tissue RNA - spleen [nTPM]":"19.8","Tissue RNA - stomach 1 [nTPM]":"28.8","Tissue RNA - testis [nTPM]":"12.7","Tissue RNA - thalamus [nTPM]":"14.6","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"52.8","Tissue RNA - tongue [nTPM]":"11.2","Tissue RNA - tonsil [nTPM]":"17.8","Tissue RNA - urinary bladder [nTPM]":"22.1","Tissue RNA - vagina [nTPM]":"11.9","Tissue RNA - white matter [nTPM]":"16.4","Cell RNA - A-431 [nTPM]":"32.4","Cell RNA - A549 [nTPM]":"18.0","Cell RNA - AF22 [nTPM]":"14.2","Cell RNA - AN3-CA [nTPM]":"40.7","Cell RNA - ASC diff [nTPM]":"57.7","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"42.6","Cell RNA - BJ [nTPM]":"44.6","Cell RNA - BJ hTERT+ [nTPM]":"40.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.4","Cell RNA - CACO-2 [nTPM]":"22.7","Cell RNA - CAPAN-2 [nTPM]":"66.5","Cell RNA - Daudi [nTPM]":"29.5","Cell RNA - EFO-21 [nTPM]":"41.5","Cell RNA - fHDF\/TERT166 [nTPM]":"45.0","Cell RNA - GAMG [nTPM]":"28.5","Cell RNA - HaCaT [nTPM]":"32.3","Cell RNA - HAP1 [nTPM]":"18.7","Cell RNA - HBEC3-KT [nTPM]":"34.1","Cell RNA - HBF TERT88 [nTPM]":"30.7","Cell RNA - HDLM-2 [nTPM]":"28.8","Cell RNA - HEK 293 [nTPM]":"8.4","Cell RNA - HEL [nTPM]":"40.7","Cell RNA - HeLa [nTPM]":"24.6","Cell RNA - Hep G2 [nTPM]":"36.5","Cell RNA - HHSteC [nTPM]":"79.1","Cell RNA - HL-60 [nTPM]":"49.8","Cell RNA - HMC-1 [nTPM]":"51.6","Cell RNA - HSkMC [nTPM]":"34.3","Cell RNA - hTCEpi [nTPM]":"35.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.7","Cell RNA - hTERT-HME1 [nTPM]":"68.2","Cell RNA - hTERT-RPE1 [nTPM]":"36.9","Cell RNA - HUVEC TERT2 [nTPM]":"44.4","Cell RNA - JURKAT [nTPM]":"13.2","Cell RNA - K-562 [nTPM]":"13.9","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"34.4","Cell RNA - MCF7 [nTPM]":"13.1","Cell RNA - MOLT-4 [nTPM]":"17.0","Cell RNA - NB-4 [nTPM]":"17.8","Cell RNA - NTERA-2 [nTPM]":"10.6","Cell RNA - OE19 [nTPM]":"75.2","Cell RNA - PC-3 [nTPM]":"13.9","Cell RNA - REH [nTPM]":"17.1","Cell RNA - RH-30 [nTPM]":"24.8","Cell RNA - RPMI-8226 [nTPM]":"22.9","Cell RNA - RPTEC TERT1 [nTPM]":"44.9","Cell RNA - RT4 [nTPM]":"39.5","Cell RNA - SCLC-21H [nTPM]":"8.2","Cell RNA - SH-SY5Y [nTPM]":"15.6","Cell RNA - SiHa [nTPM]":"31.6","Cell RNA - SK-BR-3 [nTPM]":"74.9","Cell RNA - SK-MEL-30 [nTPM]":"22.5","Cell RNA - SuSa [nTPM]":"32.4","Cell RNA - T-47d [nTPM]":"37.3","Cell RNA - THP-1 [nTPM]":"54.6","Cell RNA - TIME [nTPM]":"50.8","Cell RNA - U-138 MG [nTPM]":"39.0","Cell RNA - U-2 OS [nTPM]":"13.3","Cell RNA - U-2197 [nTPM]":"26.2","Cell RNA - U-251 MG [nTPM]":"23.3","Cell RNA - U-266\/70 [nTPM]":"60.6","Cell RNA - U-266\/84 [nTPM]":"28.4","Cell RNA - U-698 [nTPM]":"13.4","Cell RNA - U-87 MG [nTPM]":"65.6","Cell RNA - U-937 [nTPM]":"29.6","Cell RNA - WM-115 [nTPM]":"54.9","Blood RNA - basophil [nTPM]":"64.7","Blood RNA - classical monocyte [nTPM]":"25.5","Blood RNA - eosinophil [nTPM]":"86.2","Blood RNA - gdT-cell [nTPM]":"23.9","Blood RNA - intermediate monocyte [nTPM]":"32.1","Blood RNA - MAIT T-cell [nTPM]":"25.3","Blood RNA - memory B-cell [nTPM]":"11.2","Blood RNA - memory CD4 T-cell [nTPM]":"19.6","Blood RNA - memory CD8 T-cell [nTPM]":"20.1","Blood RNA - myeloid DC [nTPM]":"17.2","Blood RNA - naive B-cell [nTPM]":"9.0","Blood RNA - naive CD4 T-cell [nTPM]":"13.7","Blood RNA - naive CD8 T-cell [nTPM]":"18.7","Blood RNA - neutrophil [nTPM]":"77.1","Blood RNA - NK-cell [nTPM]":"22.8","Blood RNA - non-classical monocyte [nTPM]":"36.0","Blood RNA - plasmacytoid DC [nTPM]":"45.9","Blood RNA - T-reg [nTPM]":"13.4","Blood RNA - total PBMC [nTPM]":"15.7","Brain RNA - amygdala [nTPM]":"10.7","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"13.0","Brain RNA - cerebral cortex [nTPM]":"11.4","Brain RNA - hippocampal formation [nTPM]":"10.0","Brain RNA - hypothalamus [nTPM]":"14.1","Brain RNA - medulla oblongata [nTPM]":"15.1","Brain RNA - midbrain [nTPM]":"12.5","Brain RNA - pons [nTPM]":"15.5","Brain RNA - spinal cord [nTPM]":"13.4","Brain RNA - thalamus [nTPM]":"14.6","Brain RNA - white matter [nTPM]":"16.4","Single Cell Type RNA - Adipocytes [nTPM]":"81.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"71.3","Single Cell Type RNA - Astrocytes [nTPM]":"47.3","Single Cell Type RNA - B-cells [nTPM]":"61.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"94.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"88.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"81.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Bipolar cells [nTPM]":"25.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"35.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"58.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"81.5","Single Cell Type RNA - Club cells [nTPM]":"83.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"57.1","Single Cell Type RNA - dendritic cells [nTPM]":"109.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"69.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"98.8","Single Cell Type RNA - Early spermatids [nTPM]":"160.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"58.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"87.5","Single Cell Type RNA - Endothelial cells [nTPM]":"64.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.9","Single Cell Type RNA - Erythroid cells [nTPM]":"33.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"118.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"135.5","Single Cell Type RNA - Fibroblasts [nTPM]":"99.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"94.5","Single Cell Type RNA - granulocytes [nTPM]":"67.8","Single Cell Type RNA - Granulosa cells [nTPM]":"34.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"68.6","Single Cell Type RNA - Hepatocytes [nTPM]":"140.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"78.8","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"84.9","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"70.5","Single Cell Type RNA - Langerhans cells [nTPM]":"130.2","Single Cell Type RNA - Late spermatids [nTPM]":"33.6","Single Cell Type RNA - Leydig cells [nTPM]":"71.7","Single Cell Type RNA - Macrophages [nTPM]":"82.0","Single Cell Type RNA - Melanocytes [nTPM]":"119.2","Single Cell Type RNA - Microglial cells [nTPM]":"47.8","Single Cell Type RNA - monocytes [nTPM]":"63.1","Single Cell Type RNA - Muller glia cells [nTPM]":"38.7","Single Cell Type RNA - NK-cells [nTPM]":"51.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"53.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"58.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"97.6","Single Cell Type RNA - Paneth cells [nTPM]":"52.4","Single Cell Type RNA - Peritubular cells [nTPM]":"75.6","Single Cell Type RNA - Plasma cells [nTPM]":"214.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"151.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"58.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"71.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"96.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.6","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"80.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"104.5","Single Cell Type RNA - Spermatocytes [nTPM]":"47.1","Single Cell Type RNA - Spermatogonia [nTPM]":"79.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"92.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"189.8","Single Cell Type RNA - T-cells [nTPM]":"67.0","Single Cell Type RNA - Theca cells [nTPM]":"53.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"63.8","Single Cell Type RNA - Urothelial cells [nTPM]":"124.4"},{"Gene":"DNAL4","Gene synonym":["dJ327J16","PIG27"],"Ensembl":"ENSG00000100246","Gene description":"Dynein axonemal light chain 4","Uniprot":["O96015"],"Chromosome":"22","Position":"38778508-38794198","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"124.1","Late spermatids":"210.7","Spermatocytes":"77.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"64.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003647"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":["Nucleoplasm","Nucleoli","Cytosol"],"Antibody RRID":{"HPA003647":"AB_1078712"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.20e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.3","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"29.1","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"32.3","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"14.5","Tissue RNA - cerebellum [nTPM]":"21.0","Tissue RNA - cerebral cortex [nTPM]":"36.5","Tissue RNA - cervix [nTPM]":"18.3","Tissue RNA - choroid plexus [nTPM]":"23.2","Tissue RNA - colon [nTPM]":"12.9","Tissue RNA - duodenum [nTPM]":"7.9","Tissue RNA - endometrium 1 [nTPM]":"12.2","Tissue RNA - epididymis [nTPM]":"15.0","Tissue RNA - esophagus [nTPM]":"18.9","Tissue RNA - fallopian tube [nTPM]":"35.4","Tissue RNA - gallbladder [nTPM]":"12.9","Tissue RNA - heart muscle [nTPM]":"13.7","Tissue RNA - hippocampal formation [nTPM]":"29.2","Tissue RNA - hypothalamus [nTPM]":"28.3","Tissue RNA - kidney [nTPM]":"24.4","Tissue RNA - liver [nTPM]":"11.1","Tissue RNA - lung [nTPM]":"13.9","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"22.1","Tissue RNA - midbrain [nTPM]":"23.3","Tissue RNA - ovary [nTPM]":"17.5","Tissue RNA - pancreas [nTPM]":"21.3","Tissue RNA - parathyroid gland [nTPM]":"31.1","Tissue RNA - pituitary gland [nTPM]":"30.9","Tissue RNA - placenta [nTPM]":"9.9","Tissue RNA - pons [nTPM]":"22.1","Tissue RNA - prostate [nTPM]":"18.3","Tissue RNA - rectum [nTPM]":"9.6","Tissue RNA - retina [nTPM]":"13.8","Tissue RNA - salivary gland [nTPM]":"18.1","Tissue RNA - seminal vesicle [nTPM]":"12.1","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"22.0","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"16.4","Tissue RNA - testis [nTPM]":"65.5","Tissue RNA - thalamus [nTPM]":"28.0","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"25.4","Tissue RNA - tongue [nTPM]":"6.2","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"14.2","Tissue RNA - vagina [nTPM]":"15.5","Tissue RNA - white matter [nTPM]":"24.5","Cell RNA - A-431 [nTPM]":"17.9","Cell RNA - A549 [nTPM]":"8.9","Cell RNA - AF22 [nTPM]":"17.5","Cell RNA - AN3-CA [nTPM]":"15.5","Cell RNA - ASC diff [nTPM]":"21.8","Cell RNA - ASC TERT1 [nTPM]":"21.7","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"7.5","Cell RNA - BJ hTERT+ [nTPM]":"14.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.2","Cell RNA - CACO-2 [nTPM]":"5.7","Cell RNA - CAPAN-2 [nTPM]":"20.1","Cell RNA - Daudi [nTPM]":"4.5","Cell RNA - EFO-21 [nTPM]":"15.7","Cell RNA - fHDF\/TERT166 [nTPM]":"10.7","Cell RNA - GAMG [nTPM]":"13.1","Cell RNA - HaCaT [nTPM]":"8.3","Cell RNA - HAP1 [nTPM]":"11.0","Cell RNA - HBEC3-KT [nTPM]":"20.5","Cell RNA - HBF TERT88 [nTPM]":"7.7","Cell RNA - HDLM-2 [nTPM]":"11.4","Cell RNA - HEK 293 [nTPM]":"14.8","Cell RNA - HEL [nTPM]":"2.6","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"6.6","Cell RNA - HHSteC [nTPM]":"34.9","Cell RNA - HL-60 [nTPM]":"14.5","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"17.1","Cell RNA - hTCEpi [nTPM]":"64.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.9","Cell RNA - hTERT-HME1 [nTPM]":"26.8","Cell RNA - hTERT-RPE1 [nTPM]":"29.7","Cell RNA - HUVEC TERT2 [nTPM]":"16.6","Cell RNA - JURKAT [nTPM]":"22.1","Cell RNA - K-562 [nTPM]":"5.3","Cell RNA - Karpas-707 [nTPM]":"8.5","Cell RNA - LHCN-M2 [nTPM]":"13.8","Cell RNA - MCF7 [nTPM]":"21.9","Cell RNA - MOLT-4 [nTPM]":"13.6","Cell RNA - NB-4 [nTPM]":"14.0","Cell RNA - NTERA-2 [nTPM]":"6.8","Cell RNA - OE19 [nTPM]":"26.3","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"12.8","Cell RNA - RH-30 [nTPM]":"7.5","Cell RNA - RPMI-8226 [nTPM]":"5.9","Cell RNA - RPTEC TERT1 [nTPM]":"23.7","Cell RNA - RT4 [nTPM]":"10.8","Cell RNA - SCLC-21H [nTPM]":"24.3","Cell RNA - SH-SY5Y [nTPM]":"13.5","Cell RNA - SiHa [nTPM]":"15.4","Cell RNA - SK-BR-3 [nTPM]":"11.5","Cell RNA - SK-MEL-30 [nTPM]":"30.7","Cell RNA - SuSa [nTPM]":"12.1","Cell RNA - T-47d [nTPM]":"20.7","Cell RNA - THP-1 [nTPM]":"13.7","Cell RNA - TIME [nTPM]":"9.8","Cell RNA - U-138 MG [nTPM]":"10.1","Cell RNA - U-2 OS [nTPM]":"10.1","Cell RNA - U-2197 [nTPM]":"15.5","Cell RNA - U-251 MG [nTPM]":"7.5","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"1.8","Cell RNA - U-698 [nTPM]":"2.1","Cell RNA - U-87 MG [nTPM]":"29.9","Cell RNA - U-937 [nTPM]":"4.9","Cell RNA - WM-115 [nTPM]":"9.8","Blood RNA - basophil [nTPM]":"15.0","Blood RNA - classical monocyte [nTPM]":"8.5","Blood RNA - eosinophil [nTPM]":"11.9","Blood RNA - gdT-cell [nTPM]":"11.2","Blood RNA - intermediate monocyte [nTPM]":"8.9","Blood RNA - MAIT T-cell [nTPM]":"13.8","Blood RNA - memory B-cell [nTPM]":"7.1","Blood RNA - memory CD4 T-cell [nTPM]":"9.3","Blood RNA - memory CD8 T-cell [nTPM]":"10.2","Blood RNA - myeloid DC [nTPM]":"8.7","Blood RNA - naive B-cell [nTPM]":"10.6","Blood RNA - naive CD4 T-cell [nTPM]":"10.5","Blood RNA - naive CD8 T-cell [nTPM]":"9.0","Blood RNA - neutrophil [nTPM]":"15.0","Blood RNA - NK-cell [nTPM]":"16.2","Blood RNA - non-classical monocyte [nTPM]":"11.3","Blood RNA - plasmacytoid DC [nTPM]":"13.2","Blood RNA - T-reg [nTPM]":"9.3","Blood RNA - total PBMC [nTPM]":"7.5","Brain RNA - amygdala [nTPM]":"29.1","Brain RNA - basal ganglia [nTPM]":"32.3","Brain RNA - cerebellum [nTPM]":"21.0","Brain RNA - cerebral cortex [nTPM]":"36.5","Brain RNA - hippocampal formation [nTPM]":"29.2","Brain RNA - hypothalamus [nTPM]":"28.3","Brain RNA - medulla oblongata [nTPM]":"22.1","Brain RNA - midbrain [nTPM]":"23.3","Brain RNA - pons [nTPM]":"22.1","Brain RNA - spinal cord [nTPM]":"22.0","Brain RNA - thalamus [nTPM]":"28.0","Brain RNA - white matter [nTPM]":"24.5","Single Cell Type RNA - Adipocytes [nTPM]":"8.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.5","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"15.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.6","Single Cell Type RNA - dendritic cells [nTPM]":"9.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"28.4","Single Cell Type RNA - Early spermatids [nTPM]":"124.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"56.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.8","Single Cell Type RNA - Endothelial cells [nTPM]":"8.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.6","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.2","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.5","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"20.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"3.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.7","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.7","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"210.7","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"18.9","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"41.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.6","Single Cell Type RNA - Spermatocytes [nTPM]":"77.7","Single Cell Type RNA - Spermatogonia [nTPM]":"20.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.8","Single Cell Type RNA - T-cells [nTPM]":"6.0","Single Cell Type RNA - Theca cells [nTPM]":"20.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.2","Single Cell Type RNA - Urothelial cells [nTPM]":"12.0"},{"Gene":"DNM1","Gene synonym":["DNM"],"Ensembl":"ENSG00000106976","Gene description":"Dynamin 1","Uniprot":["Q05193"],"Chromosome":"9","Position":"128191655-128255248","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Endocytosis"],"Molecular function":["Hydrolase","Motor protein"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"319.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"112.4","Cone photoreceptor cells":"89.6","Excitatory neurons":"176.1","Inhibitory neurons":"182.2","Rod photoreceptor cells":"78.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"319.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"126.9","U-87 MG":"46.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005920","HPA049910"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8800","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB005920":null,"HPA049910":"AB_2680948"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Tissue RNA - adipose tissue [nTPM]":"22.2","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"99.8","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"129.1","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"13.2","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"319.5","Tissue RNA - cervix [nTPM]":"30.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"8.0","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"13.4","Tissue RNA - heart muscle [nTPM]":"7.8","Tissue RNA - hippocampal formation [nTPM]":"140.1","Tissue RNA - hypothalamus [nTPM]":"15.9","Tissue RNA - kidney [nTPM]":"14.1","Tissue RNA - liver [nTPM]":"5.3","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"50.7","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"33.6","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"36.6","Tissue RNA - prostate [nTPM]":"9.0","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"68.3","Tissue RNA - salivary gland [nTPM]":"9.0","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"15.0","Tissue RNA - small intestine [nTPM]":"9.0","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"4.9","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"4.0","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"10.6","Tissue RNA - vagina [nTPM]":"21.6","Tissue RNA - white matter [nTPM]":"123.1","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"126.9","Cell RNA - AF22 [nTPM]":"11.3","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"3.6","Cell RNA - ASC TERT1 [nTPM]":"36.8","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"8.0","Cell RNA - BJ hTERT+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.5","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"10.7","Cell RNA - fHDF\/TERT166 [nTPM]":"16.7","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"15.3","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"12.1","Cell RNA - HEL [nTPM]":"8.3","Cell RNA - HeLa [nTPM]":"19.5","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"2.6","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"5.6","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.4","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"7.3","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"3.6","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"2.7","Cell RNA - NTERA-2 [nTPM]":"12.2","Cell RNA - OE19 [nTPM]":"2.2","Cell RNA - PC-3 [nTPM]":"23.1","Cell RNA - REH [nTPM]":"15.6","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"3.9","Cell RNA - RPTEC TERT1 [nTPM]":"2.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"16.1","Cell RNA - SH-SY5Y [nTPM]":"27.1","Cell RNA - SiHa [nTPM]":"27.1","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"11.2","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"34.8","Cell RNA - U-2197 [nTPM]":"36.2","Cell RNA - U-251 MG [nTPM]":"16.6","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"46.8","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"2.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"99.8","Brain RNA - basal ganglia [nTPM]":"129.1","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"319.5","Brain RNA - hippocampal formation [nTPM]":"140.1","Brain RNA - hypothalamus [nTPM]":"15.9","Brain RNA - medulla oblongata [nTPM]":"50.7","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"36.6","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"123.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"18.9","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"112.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"89.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"176.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"24.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.6","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"182.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"10.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"9.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"10.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"78.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"DNM1L","Gene synonym":["DRP1","DVLP","DYMPLE","HDYNIV","VPS1"],"Ensembl":"ENSG00000087470","Gene description":"Dynamin 1 like","Uniprot":["O00429"],"Chromosome":"12","Position":"32679200-32745650","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Biological rhythms","Endocytosis","Necrosis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009952","HPA039324"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB009952":"AB_2093533","HPA039324":"AB_2676443"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.27e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.2","Tissue RNA - adrenal gland [nTPM]":"23.2","Tissue RNA - amygdala [nTPM]":"25.3","Tissue RNA - appendix [nTPM]":"23.5","Tissue RNA - basal ganglia [nTPM]":"27.5","Tissue RNA - bone marrow [nTPM]":"40.0","Tissue RNA - breast [nTPM]":"21.1","Tissue RNA - cerebellum [nTPM]":"27.7","Tissue RNA - cerebral cortex [nTPM]":"32.3","Tissue RNA - cervix [nTPM]":"18.4","Tissue RNA - choroid plexus [nTPM]":"15.7","Tissue RNA - colon [nTPM]":"24.0","Tissue RNA - duodenum [nTPM]":"18.6","Tissue RNA - endometrium 1 [nTPM]":"23.6","Tissue RNA - epididymis [nTPM]":"23.9","Tissue RNA - esophagus [nTPM]":"28.6","Tissue RNA - fallopian tube [nTPM]":"19.8","Tissue RNA - gallbladder [nTPM]":"17.5","Tissue RNA - heart muscle [nTPM]":"38.9","Tissue RNA - hippocampal formation [nTPM]":"28.4","Tissue RNA - hypothalamus [nTPM]":"26.1","Tissue RNA - kidney [nTPM]":"27.9","Tissue RNA - liver [nTPM]":"14.2","Tissue RNA - lung [nTPM]":"16.7","Tissue RNA - lymph node [nTPM]":"20.9","Tissue RNA - medulla oblongata [nTPM]":"22.5","Tissue RNA - midbrain [nTPM]":"22.0","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"13.5","Tissue RNA - parathyroid gland [nTPM]":"40.5","Tissue RNA - pituitary gland [nTPM]":"25.3","Tissue RNA - placenta [nTPM]":"23.9","Tissue RNA - pons [nTPM]":"23.6","Tissue RNA - prostate [nTPM]":"27.0","Tissue RNA - rectum [nTPM]":"22.7","Tissue RNA - retina [nTPM]":"44.9","Tissue RNA - salivary gland [nTPM]":"16.0","Tissue RNA - seminal vesicle [nTPM]":"28.7","Tissue RNA - skeletal muscle [nTPM]":"43.8","Tissue RNA - skin 1 [nTPM]":"18.3","Tissue RNA - small intestine [nTPM]":"16.8","Tissue RNA - smooth muscle [nTPM]":"32.0","Tissue RNA - spinal cord [nTPM]":"22.2","Tissue RNA - spleen [nTPM]":"18.8","Tissue RNA - stomach 1 [nTPM]":"17.3","Tissue RNA - testis [nTPM]":"36.0","Tissue RNA - thalamus [nTPM]":"21.6","Tissue RNA - thymus [nTPM]":"21.4","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"57.2","Tissue RNA - tonsil [nTPM]":"24.8","Tissue RNA - urinary bladder [nTPM]":"29.9","Tissue RNA - vagina [nTPM]":"18.5","Tissue RNA - white matter [nTPM]":"26.6","Cell RNA - A-431 [nTPM]":"66.8","Cell RNA - A549 [nTPM]":"62.3","Cell RNA - AF22 [nTPM]":"64.3","Cell RNA - AN3-CA [nTPM]":"68.3","Cell RNA - ASC diff [nTPM]":"51.2","Cell RNA - ASC TERT1 [nTPM]":"52.7","Cell RNA - BEWO [nTPM]":"123.2","Cell RNA - BJ [nTPM]":"72.0","Cell RNA - BJ hTERT+ [nTPM]":"55.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"61.7","Cell RNA - CACO-2 [nTPM]":"80.6","Cell RNA - CAPAN-2 [nTPM]":"48.0","Cell RNA - Daudi [nTPM]":"87.3","Cell RNA - EFO-21 [nTPM]":"50.0","Cell RNA - fHDF\/TERT166 [nTPM]":"65.8","Cell RNA - GAMG [nTPM]":"66.9","Cell RNA - HaCaT [nTPM]":"57.8","Cell RNA - HAP1 [nTPM]":"69.2","Cell RNA - HBEC3-KT [nTPM]":"80.3","Cell RNA - HBF TERT88 [nTPM]":"79.3","Cell RNA - HDLM-2 [nTPM]":"46.6","Cell RNA - HEK 293 [nTPM]":"57.6","Cell RNA - HEL [nTPM]":"102.3","Cell RNA - HeLa [nTPM]":"57.2","Cell RNA - Hep G2 [nTPM]":"48.2","Cell RNA - HHSteC [nTPM]":"41.7","Cell RNA - HL-60 [nTPM]":"72.5","Cell RNA - HMC-1 [nTPM]":"50.1","Cell RNA - HSkMC [nTPM]":"48.6","Cell RNA - hTCEpi [nTPM]":"37.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"70.7","Cell RNA - hTERT-HME1 [nTPM]":"66.1","Cell RNA - hTERT-RPE1 [nTPM]":"63.5","Cell RNA - HUVEC TERT2 [nTPM]":"81.1","Cell RNA - JURKAT [nTPM]":"41.4","Cell RNA - K-562 [nTPM]":"74.4","Cell RNA - Karpas-707 [nTPM]":"37.5","Cell RNA - LHCN-M2 [nTPM]":"75.3","Cell RNA - MCF7 [nTPM]":"21.7","Cell RNA - MOLT-4 [nTPM]":"29.1","Cell RNA - NB-4 [nTPM]":"61.7","Cell RNA - NTERA-2 [nTPM]":"138.2","Cell RNA - OE19 [nTPM]":"41.0","Cell RNA - PC-3 [nTPM]":"30.8","Cell RNA - REH [nTPM]":"48.6","Cell RNA - RH-30 [nTPM]":"125.0","Cell RNA - RPMI-8226 [nTPM]":"61.5","Cell RNA - RPTEC TERT1 [nTPM]":"56.5","Cell RNA - RT4 [nTPM]":"79.1","Cell RNA - SCLC-21H [nTPM]":"57.1","Cell RNA - SH-SY5Y [nTPM]":"59.3","Cell RNA - SiHa [nTPM]":"76.3","Cell RNA - SK-BR-3 [nTPM]":"51.8","Cell RNA - SK-MEL-30 [nTPM]":"56.7","Cell RNA - SuSa [nTPM]":"129.4","Cell RNA - T-47d [nTPM]":"59.7","Cell RNA - THP-1 [nTPM]":"49.0","Cell RNA - TIME [nTPM]":"74.0","Cell RNA - U-138 MG [nTPM]":"57.3","Cell RNA - U-2 OS [nTPM]":"54.4","Cell RNA - U-2197 [nTPM]":"135.3","Cell RNA - U-251 MG [nTPM]":"68.2","Cell RNA - U-266\/70 [nTPM]":"26.1","Cell RNA - U-266\/84 [nTPM]":"75.8","Cell RNA - U-698 [nTPM]":"86.3","Cell RNA - U-87 MG [nTPM]":"55.6","Cell RNA - U-937 [nTPM]":"47.0","Cell RNA - WM-115 [nTPM]":"43.5","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"10.0","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"15.6","Blood RNA - MAIT T-cell [nTPM]":"6.9","Blood RNA - memory B-cell [nTPM]":"7.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.1","Blood RNA - myeloid DC [nTPM]":"18.8","Blood RNA - naive B-cell [nTPM]":"6.0","Blood RNA - naive CD4 T-cell [nTPM]":"7.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.4","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"8.1","Blood RNA - non-classical monocyte [nTPM]":"15.6","Blood RNA - plasmacytoid DC [nTPM]":"5.6","Blood RNA - T-reg [nTPM]":"7.3","Blood RNA - total PBMC [nTPM]":"7.9","Brain RNA - amygdala [nTPM]":"25.3","Brain RNA - basal ganglia [nTPM]":"27.5","Brain RNA - cerebellum [nTPM]":"27.7","Brain RNA - cerebral cortex [nTPM]":"32.3","Brain RNA - hippocampal formation [nTPM]":"28.4","Brain RNA - hypothalamus [nTPM]":"26.1","Brain RNA - medulla oblongata [nTPM]":"22.5","Brain RNA - midbrain [nTPM]":"22.0","Brain RNA - pons [nTPM]":"23.6","Brain RNA - spinal cord [nTPM]":"22.2","Brain RNA - thalamus [nTPM]":"21.6","Brain RNA - white matter [nTPM]":"26.6","Single Cell Type RNA - Adipocytes [nTPM]":"42.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.4","Single Cell Type RNA - Astrocytes [nTPM]":"82.6","Single Cell Type RNA - B-cells [nTPM]":"36.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"80.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"82.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"33.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"131.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.0","Single Cell Type RNA - dendritic cells [nTPM]":"53.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"34.8","Single Cell Type RNA - Early spermatids [nTPM]":"63.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"55.8","Single Cell Type RNA - Endothelial cells [nTPM]":"42.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.5","Single Cell Type RNA - Erythroid cells [nTPM]":"28.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"139.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.7","Single Cell Type RNA - Fibroblasts [nTPM]":"41.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"59.4","Single Cell Type RNA - granulocytes [nTPM]":"50.7","Single Cell Type RNA - Granulosa cells [nTPM]":"48.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"16.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.8","Single Cell Type RNA - Horizontal cells [nTPM]":"126.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"150.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.9","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"27.5","Single Cell Type RNA - Langerhans cells [nTPM]":"30.7","Single Cell Type RNA - Late spermatids [nTPM]":"78.0","Single Cell Type RNA - Leydig cells [nTPM]":"26.8","Single Cell Type RNA - Macrophages [nTPM]":"43.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"45.6","Single Cell Type RNA - Muller glia cells [nTPM]":"59.0","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"99.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"121.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.7","Single Cell Type RNA - Paneth cells [nTPM]":"14.4","Single Cell Type RNA - Peritubular cells [nTPM]":"30.5","Single Cell Type RNA - Plasma cells [nTPM]":"48.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"164.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"55.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.5","Single Cell Type RNA - Spermatocytes [nTPM]":"79.3","Single Cell Type RNA - Spermatogonia [nTPM]":"52.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - T-cells [nTPM]":"42.2","Single Cell Type RNA - Theca cells [nTPM]":"26.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.5","Single Cell Type RNA - Urothelial cells [nTPM]":"36.4"},{"Gene":"DNM2","Gene synonym":["CMT2M","CMTDI1","CMTDIB","DI-CMTB","DYN2","DYNII"],"Ensembl":"ENSG00000079805","Gene description":"Dynamin 2","Uniprot":["P50570"],"Chromosome":"19","Position":"10718079-10833488","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Endocytosis","Phagocytosis"],"Molecular function":["Hydrolase","Motor protein"],"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"242.8","Paneth cells":"177.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054246"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA054246":"AB_2682427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.91e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.63e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Tissue RNA - adipose tissue [nTPM]":"55.1","Tissue RNA - adrenal gland [nTPM]":"69.9","Tissue RNA - amygdala [nTPM]":"50.5","Tissue RNA - appendix [nTPM]":"63.2","Tissue RNA - basal ganglia [nTPM]":"77.8","Tissue RNA - bone marrow [nTPM]":"125.7","Tissue RNA - breast [nTPM]":"46.1","Tissue RNA - cerebellum [nTPM]":"74.1","Tissue RNA - cerebral cortex [nTPM]":"64.1","Tissue RNA - cervix [nTPM]":"49.0","Tissue RNA - choroid plexus [nTPM]":"38.8","Tissue RNA - colon [nTPM]":"105.8","Tissue RNA - duodenum [nTPM]":"65.9","Tissue RNA - endometrium 1 [nTPM]":"42.2","Tissue RNA - epididymis [nTPM]":"25.3","Tissue RNA - esophagus [nTPM]":"67.6","Tissue RNA - fallopian tube [nTPM]":"42.5","Tissue RNA - gallbladder [nTPM]":"40.5","Tissue RNA - heart muscle [nTPM]":"87.2","Tissue RNA - hippocampal formation [nTPM]":"52.3","Tissue RNA - hypothalamus [nTPM]":"57.4","Tissue RNA - kidney [nTPM]":"72.8","Tissue RNA - liver [nTPM]":"57.2","Tissue RNA - lung [nTPM]":"87.0","Tissue RNA - lymph node [nTPM]":"62.4","Tissue RNA - medulla oblongata [nTPM]":"82.7","Tissue RNA - midbrain [nTPM]":"78.9","Tissue RNA - ovary [nTPM]":"36.6","Tissue RNA - pancreas [nTPM]":"68.2","Tissue RNA - parathyroid gland [nTPM]":"38.9","Tissue RNA - pituitary gland [nTPM]":"41.9","Tissue RNA - placenta [nTPM]":"51.3","Tissue RNA - pons [nTPM]":"79.8","Tissue RNA - prostate [nTPM]":"47.4","Tissue RNA - rectum [nTPM]":"83.9","Tissue RNA - retina [nTPM]":"30.7","Tissue RNA - salivary gland [nTPM]":"55.0","Tissue RNA - seminal vesicle [nTPM]":"55.7","Tissue RNA - skeletal muscle [nTPM]":"108.1","Tissue RNA - skin 1 [nTPM]":"92.8","Tissue RNA - small intestine [nTPM]":"99.6","Tissue RNA - smooth muscle [nTPM]":"35.1","Tissue RNA - spinal cord [nTPM]":"60.3","Tissue RNA - spleen [nTPM]":"81.0","Tissue RNA - stomach 1 [nTPM]":"98.6","Tissue RNA - testis [nTPM]":"55.1","Tissue RNA - thalamus [nTPM]":"72.9","Tissue RNA - thymus [nTPM]":"58.6","Tissue RNA - thyroid gland [nTPM]":"47.6","Tissue RNA - tongue [nTPM]":"82.8","Tissue RNA - tonsil [nTPM]":"65.4","Tissue RNA - urinary bladder [nTPM]":"64.6","Tissue RNA - vagina [nTPM]":"54.5","Tissue RNA - white matter [nTPM]":"101.6","Cell RNA - A-431 [nTPM]":"116.4","Cell RNA - A549 [nTPM]":"92.8","Cell RNA - AF22 [nTPM]":"67.6","Cell RNA - AN3-CA [nTPM]":"54.6","Cell RNA - ASC diff [nTPM]":"67.6","Cell RNA - ASC TERT1 [nTPM]":"65.4","Cell RNA - BEWO [nTPM]":"86.5","Cell RNA - BJ [nTPM]":"75.1","Cell RNA - BJ hTERT+ [nTPM]":"70.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"108.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.7","Cell RNA - CACO-2 [nTPM]":"94.2","Cell RNA - CAPAN-2 [nTPM]":"74.7","Cell RNA - Daudi [nTPM]":"83.2","Cell RNA - EFO-21 [nTPM]":"132.2","Cell RNA - fHDF\/TERT166 [nTPM]":"81.5","Cell RNA - GAMG [nTPM]":"52.5","Cell RNA - HaCaT [nTPM]":"99.4","Cell RNA - HAP1 [nTPM]":"92.6","Cell RNA - HBEC3-KT [nTPM]":"82.1","Cell RNA - HBF TERT88 [nTPM]":"90.8","Cell RNA - HDLM-2 [nTPM]":"103.1","Cell RNA - HEK 293 [nTPM]":"72.4","Cell RNA - HEL [nTPM]":"160.1","Cell RNA - HeLa [nTPM]":"81.7","Cell RNA - Hep G2 [nTPM]":"107.1","Cell RNA - HHSteC [nTPM]":"82.9","Cell RNA - HL-60 [nTPM]":"87.8","Cell RNA - HMC-1 [nTPM]":"146.5","Cell RNA - HSkMC [nTPM]":"67.8","Cell RNA - hTCEpi [nTPM]":"62.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"83.5","Cell RNA - hTERT-HME1 [nTPM]":"77.9","Cell RNA - hTERT-RPE1 [nTPM]":"66.2","Cell RNA - HUVEC TERT2 [nTPM]":"107.3","Cell RNA - JURKAT [nTPM]":"84.9","Cell RNA - K-562 [nTPM]":"131.5","Cell RNA - Karpas-707 [nTPM]":"139.1","Cell RNA - LHCN-M2 [nTPM]":"68.0","Cell RNA - MCF7 [nTPM]":"140.1","Cell RNA - MOLT-4 [nTPM]":"126.3","Cell RNA - NB-4 [nTPM]":"85.7","Cell RNA - NTERA-2 [nTPM]":"76.6","Cell RNA - OE19 [nTPM]":"138.3","Cell RNA - PC-3 [nTPM]":"109.7","Cell RNA - REH [nTPM]":"125.6","Cell RNA - RH-30 [nTPM]":"72.6","Cell RNA - RPMI-8226 [nTPM]":"95.7","Cell RNA - RPTEC TERT1 [nTPM]":"71.3","Cell RNA - RT4 [nTPM]":"171.1","Cell RNA - SCLC-21H [nTPM]":"97.1","Cell RNA - SH-SY5Y [nTPM]":"63.8","Cell RNA - SiHa [nTPM]":"86.6","Cell RNA - SK-BR-3 [nTPM]":"73.6","Cell RNA - SK-MEL-30 [nTPM]":"54.2","Cell RNA - SuSa [nTPM]":"74.9","Cell RNA - T-47d [nTPM]":"58.8","Cell RNA - THP-1 [nTPM]":"106.2","Cell RNA - TIME [nTPM]":"99.6","Cell RNA - U-138 MG [nTPM]":"120.7","Cell RNA - U-2 OS [nTPM]":"40.5","Cell RNA - U-2197 [nTPM]":"172.0","Cell RNA - U-251 MG [nTPM]":"102.7","Cell RNA - U-266\/70 [nTPM]":"112.7","Cell RNA - U-266\/84 [nTPM]":"127.3","Cell RNA - U-698 [nTPM]":"77.9","Cell RNA - U-87 MG [nTPM]":"89.9","Cell RNA - U-937 [nTPM]":"134.0","Cell RNA - WM-115 [nTPM]":"61.0","Blood RNA - basophil [nTPM]":"3.5","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"7.0","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"6.2","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"4.4","Blood RNA - myeloid DC [nTPM]":"4.2","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"6.5","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"8.4","Blood RNA - T-reg [nTPM]":"3.8","Blood RNA - total PBMC [nTPM]":"4.1","Brain RNA - amygdala [nTPM]":"50.5","Brain RNA - basal ganglia [nTPM]":"77.8","Brain RNA - cerebellum [nTPM]":"74.1","Brain RNA - cerebral cortex [nTPM]":"64.1","Brain RNA - hippocampal formation [nTPM]":"52.3","Brain RNA - hypothalamus [nTPM]":"57.4","Brain RNA - medulla oblongata [nTPM]":"82.7","Brain RNA - midbrain [nTPM]":"78.9","Brain RNA - pons [nTPM]":"79.8","Brain RNA - spinal cord [nTPM]":"60.3","Brain RNA - thalamus [nTPM]":"72.9","Brain RNA - white matter [nTPM]":"101.6","Single Cell Type RNA - Adipocytes [nTPM]":"37.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.3","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"48.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"28.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"25.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.7","Single Cell Type RNA - dendritic cells [nTPM]":"57.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"242.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.2","Single Cell Type RNA - Early spermatids [nTPM]":"48.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.9","Single Cell Type RNA - Endothelial cells [nTPM]":"33.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.6","Single Cell Type RNA - Erythroid cells [nTPM]":"38.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"106.9","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"168.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.7","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"36.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"22.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.1","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"106.9","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.0","Single Cell Type RNA - Langerhans cells [nTPM]":"39.6","Single Cell Type RNA - Late spermatids [nTPM]":"98.0","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"55.2","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"60.9","Single Cell Type RNA - monocytes [nTPM]":"43.4","Single Cell Type RNA - Muller glia cells [nTPM]":"17.2","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"90.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.2","Single Cell Type RNA - Paneth cells [nTPM]":"177.3","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"92.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"90.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.6","Single Cell Type RNA - Spermatocytes [nTPM]":"15.0","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.7","Single Cell Type RNA - T-cells [nTPM]":"46.4","Single Cell Type RNA - Theca cells [nTPM]":"40.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"82.5","Single Cell Type RNA - Urothelial cells [nTPM]":"22.8"},{"Gene":"DNMBP","Gene synonym":["ARHGEF36","KIAA1010","Tuba"],"Ensembl":"ENSG00000107554","Gene description":"Dynamin binding protein","Uniprot":["Q6XZF7"],"Chromosome":"10","Position":"99875577-100009947","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-RPE1":"75.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037878","HPA058216"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nuclear bodies","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoli","Golgi apparatus","Cytosol"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA037878":"AB_10675622","HPA058216":"AB_2683640"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.95e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.15e-4"},"Tissue RNA - adipose tissue [nTPM]":"13.6","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"10.3","Tissue RNA - breast [nTPM]":"10.2","Tissue RNA - cerebellum [nTPM]":"6.2","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"15.8","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"17.7","Tissue RNA - duodenum [nTPM]":"22.5","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"10.2","Tissue RNA - fallopian tube [nTPM]":"11.3","Tissue RNA - gallbladder [nTPM]":"11.0","Tissue RNA - heart muscle [nTPM]":"7.5","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"4.2","Tissue RNA - kidney [nTPM]":"20.6","Tissue RNA - liver [nTPM]":"13.1","Tissue RNA - lung [nTPM]":"8.4","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"17.6","Tissue RNA - parathyroid gland [nTPM]":"31.7","Tissue RNA - pituitary gland [nTPM]":"3.9","Tissue RNA - placenta [nTPM]":"10.5","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"20.7","Tissue RNA - retina [nTPM]":"15.8","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"12.8","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"27.4","Tissue RNA - small intestine [nTPM]":"27.2","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"7.7","Tissue RNA - stomach 1 [nTPM]":"23.8","Tissue RNA - testis [nTPM]":"6.9","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"20.1","Tissue RNA - thyroid gland [nTPM]":"8.1","Tissue RNA - tongue [nTPM]":"11.1","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"19.8","Tissue RNA - vagina [nTPM]":"17.7","Tissue RNA - white matter [nTPM]":"3.1","Cell RNA - A-431 [nTPM]":"25.7","Cell RNA - A549 [nTPM]":"20.7","Cell RNA - AF22 [nTPM]":"18.4","Cell RNA - AN3-CA [nTPM]":"29.2","Cell RNA - ASC diff [nTPM]":"32.9","Cell RNA - ASC TERT1 [nTPM]":"27.4","Cell RNA - BEWO [nTPM]":"4.4","Cell RNA - BJ [nTPM]":"45.2","Cell RNA - BJ hTERT+ [nTPM]":"43.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.7","Cell RNA - CACO-2 [nTPM]":"14.2","Cell RNA - CAPAN-2 [nTPM]":"38.0","Cell RNA - Daudi [nTPM]":"26.6","Cell RNA - EFO-21 [nTPM]":"18.9","Cell RNA - fHDF\/TERT166 [nTPM]":"34.9","Cell RNA - GAMG [nTPM]":"11.8","Cell RNA - HaCaT [nTPM]":"19.9","Cell RNA - HAP1 [nTPM]":"21.6","Cell RNA - HBEC3-KT [nTPM]":"26.1","Cell RNA - HBF TERT88 [nTPM]":"29.9","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"6.7","Cell RNA - HEL [nTPM]":"3.8","Cell RNA - HeLa [nTPM]":"23.7","Cell RNA - Hep G2 [nTPM]":"10.0","Cell RNA - HHSteC [nTPM]":"17.1","Cell RNA - HL-60 [nTPM]":"2.6","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"13.0","Cell RNA - hTCEpi [nTPM]":"5.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.6","Cell RNA - hTERT-HME1 [nTPM]":"23.4","Cell RNA - hTERT-RPE1 [nTPM]":"75.5","Cell RNA - HUVEC TERT2 [nTPM]":"52.1","Cell RNA - JURKAT [nTPM]":"8.5","Cell RNA - K-562 [nTPM]":"3.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"44.1","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"4.5","Cell RNA - NB-4 [nTPM]":"5.1","Cell RNA - NTERA-2 [nTPM]":"17.7","Cell RNA - OE19 [nTPM]":"18.0","Cell RNA - PC-3 [nTPM]":"12.3","Cell RNA - REH [nTPM]":"5.5","Cell RNA - RH-30 [nTPM]":"18.7","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"36.6","Cell RNA - RT4 [nTPM]":"21.9","Cell RNA - SCLC-21H [nTPM]":"3.1","Cell RNA - SH-SY5Y [nTPM]":"4.2","Cell RNA - SiHa [nTPM]":"7.4","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"5.7","Cell RNA - SuSa [nTPM]":"25.3","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"63.4","Cell RNA - U-138 MG [nTPM]":"16.0","Cell RNA - U-2 OS [nTPM]":"15.3","Cell RNA - U-2197 [nTPM]":"13.1","Cell RNA - U-251 MG [nTPM]":"29.8","Cell RNA - U-266\/70 [nTPM]":"2.1","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"36.3","Cell RNA - U-87 MG [nTPM]":"15.2","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"12.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"6.2","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"4.2","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"3.1","Single Cell Type RNA - Adipocytes [nTPM]":"6.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.0","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"14.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"4.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.0","Single Cell Type RNA - Endothelial cells [nTPM]":"12.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"17.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"43.9","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"12.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"10.7","Single Cell Type RNA - Langerhans cells [nTPM]":"9.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"20.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"3.3","Single Cell Type RNA - Muller glia cells [nTPM]":"4.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.3","Single Cell Type RNA - Paneth cells [nTPM]":"23.6","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"6.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.9","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"9.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"4.3","Single Cell Type RNA - Theca cells [nTPM]":"15.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.4","Single Cell Type RNA - Urothelial cells [nTPM]":"21.8"},{"Gene":"DNMT1","Gene synonym":["CXXC9","DNMT","MCMT"],"Ensembl":"ENSG00000130816","Gene description":"DNA methyltransferase 1","Uniprot":["P26358"],"Chromosome":"19","Position":"10133342-10231286","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","DNA-binding","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Deafness","Disease variant","FDA approved drug targets","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"388.1","Spermatocytes":"229.6","Syncytiotrophoblasts":"323.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002694","CAB005876"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB005876":"AB_731983","HPA002694":"AB_1847810"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.1","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"16.9","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"23.1","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"6.6","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"4.8","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"3.0","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"7.8","Tissue RNA - lymph node [nTPM]":"26.2","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"3.6","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"26.0","Tissue RNA - pons [nTPM]":"5.7","Tissue RNA - prostate [nTPM]":"4.5","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"5.6","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"5.3","Tissue RNA - skin 1 [nTPM]":"7.9","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"12.4","Tissue RNA - thalamus [nTPM]":"3.3","Tissue RNA - thymus [nTPM]":"20.6","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"24.9","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"10.6","Cell RNA - A-431 [nTPM]":"77.0","Cell RNA - A549 [nTPM]":"40.6","Cell RNA - AF22 [nTPM]":"49.5","Cell RNA - AN3-CA [nTPM]":"45.8","Cell RNA - ASC diff [nTPM]":"24.6","Cell RNA - ASC TERT1 [nTPM]":"24.0","Cell RNA - BEWO [nTPM]":"138.8","Cell RNA - BJ [nTPM]":"52.4","Cell RNA - BJ hTERT+ [nTPM]":"43.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"77.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"74.9","Cell RNA - CACO-2 [nTPM]":"50.6","Cell RNA - CAPAN-2 [nTPM]":"40.8","Cell RNA - Daudi [nTPM]":"138.3","Cell RNA - EFO-21 [nTPM]":"33.8","Cell RNA - fHDF\/TERT166 [nTPM]":"30.0","Cell RNA - GAMG [nTPM]":"38.6","Cell RNA - HaCaT [nTPM]":"46.6","Cell RNA - HAP1 [nTPM]":"68.4","Cell RNA - HBEC3-KT [nTPM]":"44.2","Cell RNA - HBF TERT88 [nTPM]":"68.4","Cell RNA - HDLM-2 [nTPM]":"57.5","Cell RNA - HEK 293 [nTPM]":"100.9","Cell RNA - HEL [nTPM]":"181.5","Cell RNA - HeLa [nTPM]":"39.5","Cell RNA - Hep G2 [nTPM]":"27.1","Cell RNA - HHSteC [nTPM]":"9.6","Cell RNA - HL-60 [nTPM]":"91.5","Cell RNA - HMC-1 [nTPM]":"73.4","Cell RNA - HSkMC [nTPM]":"11.5","Cell RNA - hTCEpi [nTPM]":"9.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.5","Cell RNA - hTERT-HME1 [nTPM]":"24.1","Cell RNA - hTERT-RPE1 [nTPM]":"18.4","Cell RNA - HUVEC TERT2 [nTPM]":"39.9","Cell RNA - JURKAT [nTPM]":"37.6","Cell RNA - K-562 [nTPM]":"75.0","Cell RNA - Karpas-707 [nTPM]":"82.8","Cell RNA - LHCN-M2 [nTPM]":"63.3","Cell RNA - MCF7 [nTPM]":"37.6","Cell RNA - MOLT-4 [nTPM]":"109.2","Cell RNA - NB-4 [nTPM]":"50.4","Cell RNA - NTERA-2 [nTPM]":"87.5","Cell RNA - OE19 [nTPM]":"38.3","Cell RNA - PC-3 [nTPM]":"76.6","Cell RNA - REH [nTPM]":"117.1","Cell RNA - RH-30 [nTPM]":"67.9","Cell RNA - RPMI-8226 [nTPM]":"77.2","Cell RNA - RPTEC TERT1 [nTPM]":"21.5","Cell RNA - RT4 [nTPM]":"49.3","Cell RNA - SCLC-21H [nTPM]":"64.5","Cell RNA - SH-SY5Y [nTPM]":"41.5","Cell RNA - SiHa [nTPM]":"58.2","Cell RNA - SK-BR-3 [nTPM]":"26.2","Cell RNA - SK-MEL-30 [nTPM]":"16.5","Cell RNA - SuSa [nTPM]":"33.6","Cell RNA - T-47d [nTPM]":"28.9","Cell RNA - THP-1 [nTPM]":"42.2","Cell RNA - TIME [nTPM]":"31.8","Cell RNA - U-138 MG [nTPM]":"111.3","Cell RNA - U-2 OS [nTPM]":"42.2","Cell RNA - U-2197 [nTPM]":"73.0","Cell RNA - U-251 MG [nTPM]":"84.4","Cell RNA - U-266\/70 [nTPM]":"49.6","Cell RNA - U-266\/84 [nTPM]":"69.5","Cell RNA - U-698 [nTPM]":"166.8","Cell RNA - U-87 MG [nTPM]":"35.0","Cell RNA - U-937 [nTPM]":"68.5","Cell RNA - WM-115 [nTPM]":"87.1","Blood RNA - basophil [nTPM]":"20.3","Blood RNA - classical monocyte [nTPM]":"21.2","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"29.8","Blood RNA - intermediate monocyte [nTPM]":"22.0","Blood RNA - MAIT T-cell [nTPM]":"25.1","Blood RNA - memory B-cell [nTPM]":"14.2","Blood RNA - memory CD4 T-cell [nTPM]":"22.8","Blood RNA - memory CD8 T-cell [nTPM]":"20.4","Blood RNA - myeloid DC [nTPM]":"19.3","Blood RNA - naive B-cell [nTPM]":"20.0","Blood RNA - naive CD4 T-cell [nTPM]":"25.5","Blood RNA - naive CD8 T-cell [nTPM]":"20.5","Blood RNA - neutrophil [nTPM]":"4.6","Blood RNA - NK-cell [nTPM]":"42.6","Blood RNA - non-classical monocyte [nTPM]":"13.8","Blood RNA - plasmacytoid DC [nTPM]":"31.9","Blood RNA - T-reg [nTPM]":"21.9","Blood RNA - total PBMC [nTPM]":"12.6","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"5.7","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"3.3","Brain RNA - white matter [nTPM]":"10.6","Single Cell Type RNA - Adipocytes [nTPM]":"36.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.5","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"38.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"86.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"28.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"388.1","Single Cell Type RNA - dendritic cells [nTPM]":"54.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"26.0","Single Cell Type RNA - Early spermatids [nTPM]":"46.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.0","Single Cell Type RNA - Endothelial cells [nTPM]":"38.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.7","Single Cell Type RNA - Erythroid cells [nTPM]":"109.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"73.2","Single Cell Type RNA - Fibroblasts [nTPM]":"33.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.3","Single Cell Type RNA - granulocytes [nTPM]":"37.2","Single Cell Type RNA - Granulosa cells [nTPM]":"43.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"14.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"76.8","Single Cell Type RNA - Horizontal cells [nTPM]":"65.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.5","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"31.4","Single Cell Type RNA - Langerhans cells [nTPM]":"47.8","Single Cell Type RNA - Late spermatids [nTPM]":"50.8","Single Cell Type RNA - Leydig cells [nTPM]":"28.0","Single Cell Type RNA - Macrophages [nTPM]":"57.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"52.5","Single Cell Type RNA - Muller glia cells [nTPM]":"32.2","Single Cell Type RNA - NK-cells [nTPM]":"123.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.1","Single Cell Type RNA - Paneth cells [nTPM]":"11.3","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"73.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.8","Single Cell Type RNA - Spermatocytes [nTPM]":"229.6","Single Cell Type RNA - Spermatogonia [nTPM]":"145.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"41.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"323.7","Single Cell Type RNA - T-cells [nTPM]":"70.4","Single Cell Type RNA - Theca cells [nTPM]":"38.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.1","Single Cell Type RNA - Urothelial cells [nTPM]":"16.6"},{"Gene":"DOCK7","Gene synonym":["KIAA1771","ZIR2"],"Ensembl":"ENSG00000116641","Gene description":"Dedicator of cytokinesis 7","Uniprot":["Q96N67"],"Chromosome":"1","Position":"62454298-62688386","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Guanine-nucleotide releasing factor"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"347.0","Inhibitory neurons":"103.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"11.3","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"13.6","Tissue RNA - bone marrow [nTPM]":"3.1","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"11.6","Tissue RNA - cervix [nTPM]":"10.7","Tissue RNA - choroid plexus [nTPM]":"7.2","Tissue RNA - colon [nTPM]":"9.9","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"7.7","Tissue RNA - esophagus [nTPM]":"6.5","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"5.9","Tissue RNA - hippocampal formation [nTPM]":"10.3","Tissue RNA - hypothalamus [nTPM]":"13.6","Tissue RNA - kidney [nTPM]":"8.9","Tissue RNA - liver [nTPM]":"8.0","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"11.3","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"15.4","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"13.9","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"9.9","Tissue RNA - pons [nTPM]":"12.4","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"11.3","Tissue RNA - retina [nTPM]":"12.6","Tissue RNA - salivary gland [nTPM]":"9.8","Tissue RNA - seminal vesicle [nTPM]":"7.9","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"9.8","Tissue RNA - small intestine [nTPM]":"6.7","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"12.9","Tissue RNA - spleen [nTPM]":"6.1","Tissue RNA - stomach 1 [nTPM]":"10.6","Tissue RNA - testis [nTPM]":"16.4","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"7.3","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"8.0","Tissue RNA - white matter [nTPM]":"15.2","Cell RNA - A-431 [nTPM]":"30.8","Cell RNA - A549 [nTPM]":"12.3","Cell RNA - AF22 [nTPM]":"48.8","Cell RNA - AN3-CA [nTPM]":"10.9","Cell RNA - ASC diff [nTPM]":"45.8","Cell RNA - ASC TERT1 [nTPM]":"49.6","Cell RNA - BEWO [nTPM]":"22.6","Cell RNA - BJ [nTPM]":"41.9","Cell RNA - BJ hTERT+ [nTPM]":"37.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.5","Cell RNA - CACO-2 [nTPM]":"13.4","Cell RNA - CAPAN-2 [nTPM]":"9.6","Cell RNA - Daudi [nTPM]":"13.3","Cell RNA - EFO-21 [nTPM]":"9.4","Cell RNA - fHDF\/TERT166 [nTPM]":"56.6","Cell RNA - GAMG [nTPM]":"42.4","Cell RNA - HaCaT [nTPM]":"16.2","Cell RNA - HAP1 [nTPM]":"23.7","Cell RNA - HBEC3-KT [nTPM]":"34.4","Cell RNA - HBF TERT88 [nTPM]":"57.9","Cell RNA - HDLM-2 [nTPM]":"15.9","Cell RNA - HEK 293 [nTPM]":"18.2","Cell RNA - HEL [nTPM]":"24.1","Cell RNA - HeLa [nTPM]":"11.8","Cell RNA - Hep G2 [nTPM]":"25.0","Cell RNA - HHSteC [nTPM]":"20.8","Cell RNA - HL-60 [nTPM]":"11.1","Cell RNA - HMC-1 [nTPM]":"8.7","Cell RNA - HSkMC [nTPM]":"30.0","Cell RNA - hTCEpi [nTPM]":"15.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.5","Cell RNA - hTERT-HME1 [nTPM]":"38.4","Cell RNA - hTERT-RPE1 [nTPM]":"42.8","Cell RNA - HUVEC TERT2 [nTPM]":"17.8","Cell RNA - JURKAT [nTPM]":"12.7","Cell RNA - K-562 [nTPM]":"11.7","Cell RNA - Karpas-707 [nTPM]":"5.0","Cell RNA - LHCN-M2 [nTPM]":"43.2","Cell RNA - MCF7 [nTPM]":"9.2","Cell RNA - MOLT-4 [nTPM]":"8.7","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"26.3","Cell RNA - OE19 [nTPM]":"6.6","Cell RNA - PC-3 [nTPM]":"14.3","Cell RNA - REH [nTPM]":"10.6","Cell RNA - RH-30 [nTPM]":"53.1","Cell RNA - RPMI-8226 [nTPM]":"3.7","Cell RNA - RPTEC TERT1 [nTPM]":"28.9","Cell RNA - RT4 [nTPM]":"26.4","Cell RNA - SCLC-21H [nTPM]":"15.3","Cell RNA - SH-SY5Y [nTPM]":"49.2","Cell RNA - SiHa [nTPM]":"23.5","Cell RNA - SK-BR-3 [nTPM]":"24.6","Cell RNA - SK-MEL-30 [nTPM]":"51.9","Cell RNA - SuSa [nTPM]":"42.9","Cell RNA - T-47d [nTPM]":"7.8","Cell RNA - THP-1 [nTPM]":"8.5","Cell RNA - TIME [nTPM]":"31.7","Cell RNA - U-138 MG [nTPM]":"37.6","Cell RNA - U-2 OS [nTPM]":"21.4","Cell RNA - U-2197 [nTPM]":"37.3","Cell RNA - U-251 MG [nTPM]":"31.5","Cell RNA - U-266\/70 [nTPM]":"9.3","Cell RNA - U-266\/84 [nTPM]":"12.7","Cell RNA - U-698 [nTPM]":"7.2","Cell RNA - U-87 MG [nTPM]":"32.1","Cell RNA - U-937 [nTPM]":"2.7","Cell RNA - WM-115 [nTPM]":"40.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"11.3","Brain RNA - basal ganglia [nTPM]":"13.6","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"11.6","Brain RNA - hippocampal formation [nTPM]":"10.3","Brain RNA - hypothalamus [nTPM]":"13.6","Brain RNA - medulla oblongata [nTPM]":"11.3","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"12.4","Brain RNA - spinal cord [nTPM]":"12.9","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"15.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.1","Single Cell Type RNA - Astrocytes [nTPM]":"347.0","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"15.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.8","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"19.9","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.6","Single Cell Type RNA - Endothelial cells [nTPM]":"6.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"7.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"84.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.1","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.1","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"29.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"16.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.3","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"103.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.5","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.7","Single Cell Type RNA - Langerhans cells [nTPM]":"9.5","Single Cell Type RNA - Late spermatids [nTPM]":"4.5","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"13.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"7.0","Single Cell Type RNA - Muller glia cells [nTPM]":"23.8","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"53.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.5","Single Cell Type RNA - Paneth cells [nTPM]":"14.5","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.4","Single Cell Type RNA - Spermatocytes [nTPM]":"48.8","Single Cell Type RNA - Spermatogonia [nTPM]":"43.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.6","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"15.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.6","Single Cell Type RNA - Urothelial cells [nTPM]":"13.8"},{"Gene":"DOK7","Gene synonym":["C4orf25","Dok-7","FLJ33718","FLJ39137"],"Ensembl":"ENSG00000175920","Gene description":"Docking protein 7","Uniprot":["Q18PE1"],"Chromosome":"4","Position":"3463306-3501473","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"41.9","skeletal muscle":"29.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"17.1","Enteroendocrine cells":"6.0","Late spermatids":"9.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"11.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"memory B-cell":"3.4","naive B-cell":"2.3","NK-cell":"1.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"B-cells":"3.4","NK-cells":"1.9"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"MCF7":"36.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059449","HPA062780"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA059449":"AB_2684023","HPA062780":"AB_2732688"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.19e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.28e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"4.7","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"2.9","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"11.1","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"5.9","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"41.9","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"2.7","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"15.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"29.5","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"2.7","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"8.8","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"2.7","Cell RNA - A549 [nTPM]":"0.9","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"4.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"4.4","Cell RNA - MCF7 [nTPM]":"36.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"6.7","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"3.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"3.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"8.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"4.7","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"2.9","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"5.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"9.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"DPAGT1","Gene synonym":["ALG7","CDG-Ij","D11S366","DGPT","DPAGT","DPAGT2","GPT"],"Ensembl":"ENSG00000172269","Gene description":"Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1","Uniprot":["Q9H3H5"],"Chromosome":"11","Position":"119096503-119108331","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053878"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053878":"AB_2682288"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.3","Tissue RNA - adrenal gland [nTPM]":"14.1","Tissue RNA - amygdala [nTPM]":"13.0","Tissue RNA - appendix [nTPM]":"13.7","Tissue RNA - basal ganglia [nTPM]":"13.3","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"14.8","Tissue RNA - cerebellum [nTPM]":"13.9","Tissue RNA - cerebral cortex [nTPM]":"22.4","Tissue RNA - cervix [nTPM]":"16.1","Tissue RNA - choroid plexus [nTPM]":"17.6","Tissue RNA - colon [nTPM]":"17.7","Tissue RNA - duodenum [nTPM]":"16.8","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"21.8","Tissue RNA - esophagus [nTPM]":"12.4","Tissue RNA - fallopian tube [nTPM]":"17.3","Tissue RNA - gallbladder [nTPM]":"14.5","Tissue RNA - heart muscle [nTPM]":"8.6","Tissue RNA - hippocampal formation [nTPM]":"13.5","Tissue RNA - hypothalamus [nTPM]":"14.1","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"21.2","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"11.5","Tissue RNA - medulla oblongata [nTPM]":"14.2","Tissue RNA - midbrain [nTPM]":"14.4","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"27.1","Tissue RNA - parathyroid gland [nTPM]":"18.6","Tissue RNA - pituitary gland [nTPM]":"4.4","Tissue RNA - placenta [nTPM]":"15.8","Tissue RNA - pons [nTPM]":"14.2","Tissue RNA - prostate [nTPM]":"14.3","Tissue RNA - rectum [nTPM]":"20.0","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"27.8","Tissue RNA - seminal vesicle [nTPM]":"16.3","Tissue RNA - skeletal muscle [nTPM]":"5.6","Tissue RNA - skin 1 [nTPM]":"9.0","Tissue RNA - small intestine [nTPM]":"14.9","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"13.4","Tissue RNA - spleen [nTPM]":"9.8","Tissue RNA - stomach 1 [nTPM]":"14.4","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"14.6","Tissue RNA - thymus [nTPM]":"8.2","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"8.5","Tissue RNA - tonsil [nTPM]":"14.3","Tissue RNA - urinary bladder [nTPM]":"16.8","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"22.0","Cell RNA - A549 [nTPM]":"39.2","Cell RNA - AF22 [nTPM]":"22.2","Cell RNA - AN3-CA [nTPM]":"55.7","Cell RNA - ASC diff [nTPM]":"60.0","Cell RNA - ASC TERT1 [nTPM]":"37.0","Cell RNA - BEWO [nTPM]":"24.6","Cell RNA - BJ [nTPM]":"33.7","Cell RNA - BJ hTERT+ [nTPM]":"38.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.2","Cell RNA - CACO-2 [nTPM]":"43.4","Cell RNA - CAPAN-2 [nTPM]":"88.3","Cell RNA - Daudi [nTPM]":"41.5","Cell RNA - EFO-21 [nTPM]":"62.8","Cell RNA - fHDF\/TERT166 [nTPM]":"45.4","Cell RNA - GAMG [nTPM]":"57.7","Cell RNA - HaCaT [nTPM]":"77.1","Cell RNA - HAP1 [nTPM]":"42.0","Cell RNA - HBEC3-KT [nTPM]":"60.7","Cell RNA - HBF TERT88 [nTPM]":"31.1","Cell RNA - HDLM-2 [nTPM]":"29.4","Cell RNA - HEK 293 [nTPM]":"23.8","Cell RNA - HEL [nTPM]":"83.5","Cell RNA - HeLa [nTPM]":"14.1","Cell RNA - Hep G2 [nTPM]":"51.6","Cell RNA - HHSteC [nTPM]":"50.7","Cell RNA - HL-60 [nTPM]":"53.9","Cell RNA - HMC-1 [nTPM]":"47.4","Cell RNA - HSkMC [nTPM]":"40.3","Cell RNA - hTCEpi [nTPM]":"48.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"62.4","Cell RNA - hTERT-HME1 [nTPM]":"85.3","Cell RNA - hTERT-RPE1 [nTPM]":"29.9","Cell RNA - HUVEC TERT2 [nTPM]":"53.3","Cell RNA - JURKAT [nTPM]":"25.2","Cell RNA - K-562 [nTPM]":"51.7","Cell RNA - Karpas-707 [nTPM]":"84.1","Cell RNA - LHCN-M2 [nTPM]":"50.9","Cell RNA - MCF7 [nTPM]":"67.7","Cell RNA - MOLT-4 [nTPM]":"19.5","Cell RNA - NB-4 [nTPM]":"39.9","Cell RNA - NTERA-2 [nTPM]":"22.5","Cell RNA - OE19 [nTPM]":"148.3","Cell RNA - PC-3 [nTPM]":"49.4","Cell RNA - REH [nTPM]":"26.2","Cell RNA - RH-30 [nTPM]":"26.6","Cell RNA - RPMI-8226 [nTPM]":"61.3","Cell RNA - RPTEC TERT1 [nTPM]":"60.3","Cell RNA - RT4 [nTPM]":"44.7","Cell RNA - SCLC-21H [nTPM]":"23.0","Cell RNA - SH-SY5Y [nTPM]":"30.1","Cell RNA - SiHa [nTPM]":"30.7","Cell RNA - SK-BR-3 [nTPM]":"99.3","Cell RNA - SK-MEL-30 [nTPM]":"17.1","Cell RNA - SuSa [nTPM]":"32.3","Cell RNA - T-47d [nTPM]":"116.8","Cell RNA - THP-1 [nTPM]":"19.4","Cell RNA - TIME [nTPM]":"29.1","Cell RNA - U-138 MG [nTPM]":"57.3","Cell RNA - U-2 OS [nTPM]":"24.5","Cell RNA - U-2197 [nTPM]":"30.3","Cell RNA - U-251 MG [nTPM]":"23.7","Cell RNA - U-266\/70 [nTPM]":"19.6","Cell RNA - U-266\/84 [nTPM]":"32.2","Cell RNA - U-698 [nTPM]":"13.9","Cell RNA - U-87 MG [nTPM]":"14.3","Cell RNA - U-937 [nTPM]":"68.3","Cell RNA - WM-115 [nTPM]":"48.9","Blood RNA - basophil [nTPM]":"28.4","Blood RNA - classical monocyte [nTPM]":"35.7","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"25.2","Blood RNA - intermediate monocyte [nTPM]":"35.5","Blood RNA - MAIT T-cell [nTPM]":"28.4","Blood RNA - memory B-cell [nTPM]":"24.5","Blood RNA - memory CD4 T-cell [nTPM]":"20.1","Blood RNA - memory CD8 T-cell [nTPM]":"24.8","Blood RNA - myeloid DC [nTPM]":"43.3","Blood RNA - naive B-cell [nTPM]":"25.6","Blood RNA - naive CD4 T-cell [nTPM]":"16.6","Blood RNA - naive CD8 T-cell [nTPM]":"15.8","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"20.7","Blood RNA - non-classical monocyte [nTPM]":"32.7","Blood RNA - plasmacytoid DC [nTPM]":"37.5","Blood RNA - T-reg [nTPM]":"19.6","Blood RNA - total PBMC [nTPM]":"20.2","Brain RNA - amygdala [nTPM]":"13.0","Brain RNA - basal ganglia [nTPM]":"13.3","Brain RNA - cerebellum [nTPM]":"13.9","Brain RNA - cerebral cortex [nTPM]":"22.4","Brain RNA - hippocampal formation [nTPM]":"13.5","Brain RNA - hypothalamus [nTPM]":"14.1","Brain RNA - medulla oblongata [nTPM]":"14.2","Brain RNA - midbrain [nTPM]":"14.4","Brain RNA - pons [nTPM]":"14.2","Brain RNA - spinal cord [nTPM]":"13.4","Brain RNA - thalamus [nTPM]":"14.6","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.1","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"10.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"6.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"22.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - dendritic cells [nTPM]":"9.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"32.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.3","Single Cell Type RNA - Endothelial cells [nTPM]":"16.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.4","Single Cell Type RNA - Fibroblasts [nTPM]":"11.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.2","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"12.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"23.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.8","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"13.0","Single Cell Type RNA - Langerhans cells [nTPM]":"11.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"14.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"20.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.2","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.9","Single Cell Type RNA - Paneth cells [nTPM]":"11.1","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.5","Single Cell Type RNA - T-cells [nTPM]":"10.0","Single Cell Type RNA - Theca cells [nTPM]":"15.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.7","Single Cell Type RNA - Urothelial cells [nTPM]":"12.9"},{"Gene":"DRAM2","Gene synonym":["MGC54289","PRO180","RP5-1180E21.1","TMEM77","WWFQ154"],"Ensembl":"ENSG00000156171","Gene description":"DNA damage regulated autophagy modulator 2","Uniprot":["Q6UX65"],"Chromosome":"1","Position":"111117163-111140203","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Autophagy"],"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018036","HPA061701"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA018036":"AB_1858134","HPA061701":"AB_2684590"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.45e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.43e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Tissue RNA - adipose tissue [nTPM]":"38.0","Tissue RNA - adrenal gland [nTPM]":"23.1","Tissue RNA - amygdala [nTPM]":"13.9","Tissue RNA - appendix [nTPM]":"33.1","Tissue RNA - basal ganglia [nTPM]":"14.5","Tissue RNA - bone marrow [nTPM]":"17.9","Tissue RNA - breast [nTPM]":"26.8","Tissue RNA - cerebellum [nTPM]":"17.7","Tissue RNA - cerebral cortex [nTPM]":"19.9","Tissue RNA - cervix [nTPM]":"23.1","Tissue RNA - choroid plexus [nTPM]":"22.7","Tissue RNA - colon [nTPM]":"26.7","Tissue RNA - duodenum [nTPM]":"28.6","Tissue RNA - endometrium 1 [nTPM]":"17.7","Tissue RNA - epididymis [nTPM]":"17.6","Tissue RNA - esophagus [nTPM]":"15.0","Tissue RNA - fallopian tube [nTPM]":"30.1","Tissue RNA - gallbladder [nTPM]":"36.4","Tissue RNA - heart muscle [nTPM]":"23.7","Tissue RNA - hippocampal formation [nTPM]":"13.5","Tissue RNA - hypothalamus [nTPM]":"15.2","Tissue RNA - kidney [nTPM]":"26.5","Tissue RNA - liver [nTPM]":"24.9","Tissue RNA - lung [nTPM]":"25.0","Tissue RNA - lymph node [nTPM]":"55.3","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"14.9","Tissue RNA - ovary [nTPM]":"24.3","Tissue RNA - pancreas [nTPM]":"25.6","Tissue RNA - parathyroid gland [nTPM]":"28.3","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"41.2","Tissue RNA - pons [nTPM]":"16.2","Tissue RNA - prostate [nTPM]":"17.8","Tissue RNA - rectum [nTPM]":"30.7","Tissue RNA - retina [nTPM]":"16.9","Tissue RNA - salivary gland [nTPM]":"25.8","Tissue RNA - seminal vesicle [nTPM]":"16.7","Tissue RNA - skeletal muscle [nTPM]":"16.6","Tissue RNA - skin 1 [nTPM]":"17.9","Tissue RNA - small intestine [nTPM]":"26.3","Tissue RNA - smooth muscle [nTPM]":"17.0","Tissue RNA - spinal cord [nTPM]":"15.5","Tissue RNA - spleen [nTPM]":"45.3","Tissue RNA - stomach 1 [nTPM]":"23.4","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"15.0","Tissue RNA - thymus [nTPM]":"27.8","Tissue RNA - thyroid gland [nTPM]":"22.0","Tissue RNA - tongue [nTPM]":"23.6","Tissue RNA - tonsil [nTPM]":"50.3","Tissue RNA - urinary bladder [nTPM]":"29.4","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"17.8","Cell RNA - A-431 [nTPM]":"38.0","Cell RNA - A549 [nTPM]":"12.9","Cell RNA - AF22 [nTPM]":"24.0","Cell RNA - AN3-CA [nTPM]":"10.8","Cell RNA - ASC diff [nTPM]":"57.3","Cell RNA - ASC TERT1 [nTPM]":"56.2","Cell RNA - BEWO [nTPM]":"23.4","Cell RNA - BJ [nTPM]":"28.7","Cell RNA - BJ hTERT+ [nTPM]":"29.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.9","Cell RNA - CACO-2 [nTPM]":"12.5","Cell RNA - CAPAN-2 [nTPM]":"38.2","Cell RNA - Daudi [nTPM]":"28.7","Cell RNA - EFO-21 [nTPM]":"17.2","Cell RNA - fHDF\/TERT166 [nTPM]":"25.6","Cell RNA - GAMG [nTPM]":"12.1","Cell RNA - HaCaT [nTPM]":"37.4","Cell RNA - HAP1 [nTPM]":"30.5","Cell RNA - HBEC3-KT [nTPM]":"24.0","Cell RNA - HBF TERT88 [nTPM]":"31.9","Cell RNA - HDLM-2 [nTPM]":"26.8","Cell RNA - HEK 293 [nTPM]":"25.6","Cell RNA - HEL [nTPM]":"16.8","Cell RNA - HeLa [nTPM]":"18.4","Cell RNA - Hep G2 [nTPM]":"16.4","Cell RNA - HHSteC [nTPM]":"41.4","Cell RNA - HL-60 [nTPM]":"19.4","Cell RNA - HMC-1 [nTPM]":"15.4","Cell RNA - HSkMC [nTPM]":"38.5","Cell RNA - hTCEpi [nTPM]":"41.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.3","Cell RNA - hTERT-HME1 [nTPM]":"38.4","Cell RNA - hTERT-RPE1 [nTPM]":"53.6","Cell RNA - HUVEC TERT2 [nTPM]":"29.9","Cell RNA - JURKAT [nTPM]":"29.1","Cell RNA - K-562 [nTPM]":"34.1","Cell RNA - Karpas-707 [nTPM]":"19.6","Cell RNA - LHCN-M2 [nTPM]":"30.1","Cell RNA - MCF7 [nTPM]":"19.6","Cell RNA - MOLT-4 [nTPM]":"16.6","Cell RNA - NB-4 [nTPM]":"28.8","Cell RNA - NTERA-2 [nTPM]":"14.5","Cell RNA - OE19 [nTPM]":"43.3","Cell RNA - PC-3 [nTPM]":"13.2","Cell RNA - REH [nTPM]":"11.1","Cell RNA - RH-30 [nTPM]":"40.0","Cell RNA - RPMI-8226 [nTPM]":"14.0","Cell RNA - RPTEC TERT1 [nTPM]":"42.5","Cell RNA - RT4 [nTPM]":"25.8","Cell RNA - SCLC-21H [nTPM]":"19.1","Cell RNA - SH-SY5Y [nTPM]":"18.2","Cell RNA - SiHa [nTPM]":"16.8","Cell RNA - SK-BR-3 [nTPM]":"52.4","Cell RNA - SK-MEL-30 [nTPM]":"80.1","Cell RNA - SuSa [nTPM]":"33.1","Cell RNA - T-47d [nTPM]":"16.7","Cell RNA - THP-1 [nTPM]":"84.6","Cell RNA - TIME [nTPM]":"24.8","Cell RNA - U-138 MG [nTPM]":"20.6","Cell RNA - U-2 OS [nTPM]":"13.8","Cell RNA - U-2197 [nTPM]":"16.2","Cell RNA - U-251 MG [nTPM]":"18.9","Cell RNA - U-266\/70 [nTPM]":"25.7","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"29.8","Cell RNA - U-87 MG [nTPM]":"33.4","Cell RNA - U-937 [nTPM]":"34.7","Cell RNA - WM-115 [nTPM]":"29.6","Blood RNA - basophil [nTPM]":"41.7","Blood RNA - classical monocyte [nTPM]":"47.3","Blood RNA - eosinophil [nTPM]":"11.5","Blood RNA - gdT-cell [nTPM]":"14.2","Blood RNA - intermediate monocyte [nTPM]":"61.0","Blood RNA - MAIT T-cell [nTPM]":"19.4","Blood RNA - memory B-cell [nTPM]":"65.7","Blood RNA - memory CD4 T-cell [nTPM]":"17.5","Blood RNA - memory CD8 T-cell [nTPM]":"15.3","Blood RNA - myeloid DC [nTPM]":"45.1","Blood RNA - naive B-cell [nTPM]":"54.1","Blood RNA - naive CD4 T-cell [nTPM]":"22.3","Blood RNA - naive CD8 T-cell [nTPM]":"19.0","Blood RNA - neutrophil [nTPM]":"7.2","Blood RNA - NK-cell [nTPM]":"25.0","Blood RNA - non-classical monocyte [nTPM]":"49.8","Blood RNA - plasmacytoid DC [nTPM]":"28.6","Blood RNA - T-reg [nTPM]":"17.7","Blood RNA - total PBMC [nTPM]":"35.5","Brain RNA - amygdala [nTPM]":"13.9","Brain RNA - basal ganglia [nTPM]":"14.5","Brain RNA - cerebellum [nTPM]":"17.7","Brain RNA - cerebral cortex [nTPM]":"19.9","Brain RNA - hippocampal formation [nTPM]":"13.5","Brain RNA - hypothalamus [nTPM]":"15.2","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"14.9","Brain RNA - pons [nTPM]":"16.2","Brain RNA - spinal cord [nTPM]":"15.5","Brain RNA - thalamus [nTPM]":"15.0","Brain RNA - white matter [nTPM]":"17.8","Single Cell Type RNA - Adipocytes [nTPM]":"34.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.0","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"146.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"47.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"54.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"82.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"53.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"53.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"98.1","Single Cell Type RNA - dendritic cells [nTPM]":"38.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"59.2","Single Cell Type RNA - Early spermatids [nTPM]":"8.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.5","Single Cell Type RNA - Endothelial cells [nTPM]":"36.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"28.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"46.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"102.3","Single Cell Type RNA - Fibroblasts [nTPM]":"39.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.6","Single Cell Type RNA - granulocytes [nTPM]":"23.6","Single Cell Type RNA - Granulosa cells [nTPM]":"18.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.8","Single Cell Type RNA - Hepatocytes [nTPM]":"26.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"183.1","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"45.7","Single Cell Type RNA - Ionocytes [nTPM]":"77.3","Single Cell Type RNA - Kupffer cells [nTPM]":"189.4","Single Cell Type RNA - Langerhans cells [nTPM]":"97.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"33.5","Single Cell Type RNA - Macrophages [nTPM]":"110.3","Single Cell Type RNA - Melanocytes [nTPM]":"81.8","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"89.0","Single Cell Type RNA - Muller glia cells [nTPM]":"27.1","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"41.9","Single Cell Type RNA - Paneth cells [nTPM]":"64.3","Single Cell Type RNA - Peritubular cells [nTPM]":"24.8","Single Cell Type RNA - Plasma cells [nTPM]":"54.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"88.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"80.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"95.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.5","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"53.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"73.3","Single Cell Type RNA - T-cells [nTPM]":"38.6","Single Cell Type RNA - Theca cells [nTPM]":"26.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.7","Single Cell Type RNA - Urothelial cells [nTPM]":"70.1"},{"Gene":"DRD3","Gene synonym":[],"Ensembl":"ENSG00000151577","Gene description":"Dopamine receptor D3","Uniprot":["P35462"],"Chromosome":"3","Position":"114127580-114199407","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets","Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"5.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Early spermatids":"6.2","Late spermatids":"19.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"basal ganglia":"5.6","cerebral cortex":"2.8","hypothalamus":"4.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"7.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"10","RNA pig brain regional specific nTPM":{"basal ganglia":"17.9"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"5.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"5.6","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"19.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"DSPP","Gene synonym":["DFNA39","DGI1","DMP3"],"Ensembl":"ENSG00000152591","Gene description":"Dentin sialophosphoprotein","Uniprot":["Q9NZW4"],"Chromosome":"4","Position":"87608529-87616873","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Biomineralization"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036230"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000","Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036230":"AB_10672239"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"DST","Gene synonym":["BP240","BPA","BPAG1","CATX-15","FLJ13425","FLJ21489","FLJ30627","FLJ32235","KIAA0728","MACF2"],"Ensembl":"ENSG00000151914","Gene description":"Dystonin","Uniprot":["Q03001"],"Chromosome":"6","Position":"56457987-56954830","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Actin-binding","Muscle protein"],"Disease involvement":["Cancer-related genes","Epidermolysis bullosa","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"2368.6","Basal prostatic cells":"1651.4","Basal squamous epithelial cells":"3008.4","Cone photoreceptor cells":"1401.1","Oligodendrocytes":"1410.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"488.1","hTERT-HME1":"371.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030200"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm","Microtubules"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA030200":"AB_10601901"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"60.9","Tissue RNA - adrenal gland [nTPM]":"86.2","Tissue RNA - amygdala [nTPM]":"206.5","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"275.8","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"117.3","Tissue RNA - cerebellum [nTPM]":"240.6","Tissue RNA - cerebral cortex [nTPM]":"221.9","Tissue RNA - cervix [nTPM]":"158.8","Tissue RNA - choroid plexus [nTPM]":"143.3","Tissue RNA - colon [nTPM]":"173.2","Tissue RNA - duodenum [nTPM]":"25.4","Tissue RNA - endometrium 1 [nTPM]":"167.1","Tissue RNA - epididymis [nTPM]":"38.2","Tissue RNA - esophagus [nTPM]":"66.1","Tissue RNA - fallopian tube [nTPM]":"103.9","Tissue RNA - gallbladder [nTPM]":"32.6","Tissue RNA - heart muscle [nTPM]":"166.0","Tissue RNA - hippocampal formation [nTPM]":"194.6","Tissue RNA - hypothalamus [nTPM]":"230.7","Tissue RNA - kidney [nTPM]":"52.2","Tissue RNA - liver [nTPM]":"80.8","Tissue RNA - lung [nTPM]":"108.0","Tissue RNA - lymph node [nTPM]":"11.3","Tissue RNA - medulla oblongata [nTPM]":"258.1","Tissue RNA - midbrain [nTPM]":"250.4","Tissue RNA - ovary [nTPM]":"78.2","Tissue RNA - pancreas [nTPM]":"39.8","Tissue RNA - parathyroid gland [nTPM]":"36.7","Tissue RNA - pituitary gland [nTPM]":"78.8","Tissue RNA - placenta [nTPM]":"28.7","Tissue RNA - pons [nTPM]":"263.4","Tissue RNA - prostate [nTPM]":"84.5","Tissue RNA - rectum [nTPM]":"32.4","Tissue RNA - retina [nTPM]":"87.4","Tissue RNA - salivary gland [nTPM]":"100.3","Tissue RNA - seminal vesicle [nTPM]":"48.7","Tissue RNA - skeletal muscle [nTPM]":"143.1","Tissue RNA - skin 1 [nTPM]":"166.2","Tissue RNA - small intestine [nTPM]":"64.2","Tissue RNA - smooth muscle [nTPM]":"106.0","Tissue RNA - spinal cord [nTPM]":"209.1","Tissue RNA - spleen [nTPM]":"36.7","Tissue RNA - stomach 1 [nTPM]":"68.9","Tissue RNA - testis [nTPM]":"28.4","Tissue RNA - thalamus [nTPM]":"243.3","Tissue RNA - thymus [nTPM]":"31.4","Tissue RNA - thyroid gland [nTPM]":"29.8","Tissue RNA - tongue [nTPM]":"104.1","Tissue RNA - tonsil [nTPM]":"15.2","Tissue RNA - urinary bladder [nTPM]":"90.4","Tissue RNA - vagina [nTPM]":"113.2","Tissue RNA - white matter [nTPM]":"325.4","Cell RNA - A-431 [nTPM]":"62.4","Cell RNA - A549 [nTPM]":"26.6","Cell RNA - AF22 [nTPM]":"41.2","Cell RNA - AN3-CA [nTPM]":"20.8","Cell RNA - ASC diff [nTPM]":"79.5","Cell RNA - ASC TERT1 [nTPM]":"103.5","Cell RNA - BEWO [nTPM]":"24.6","Cell RNA - BJ [nTPM]":"82.2","Cell RNA - BJ hTERT+ [nTPM]":"89.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"37.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.1","Cell RNA - CACO-2 [nTPM]":"17.1","Cell RNA - CAPAN-2 [nTPM]":"15.5","Cell RNA - Daudi [nTPM]":"10.4","Cell RNA - EFO-21 [nTPM]":"32.2","Cell RNA - fHDF\/TERT166 [nTPM]":"220.7","Cell RNA - GAMG [nTPM]":"35.6","Cell RNA - HaCaT [nTPM]":"46.7","Cell RNA - HAP1 [nTPM]":"34.4","Cell RNA - HBEC3-KT [nTPM]":"161.2","Cell RNA - HBF TERT88 [nTPM]":"73.0","Cell RNA - HDLM-2 [nTPM]":"52.3","Cell RNA - HEK 293 [nTPM]":"45.2","Cell RNA - HEL [nTPM]":"17.8","Cell RNA - HeLa [nTPM]":"49.5","Cell RNA - Hep G2 [nTPM]":"31.4","Cell RNA - HHSteC [nTPM]":"65.9","Cell RNA - HL-60 [nTPM]":"15.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"58.3","Cell RNA - hTCEpi [nTPM]":"488.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"92.5","Cell RNA - hTERT-HME1 [nTPM]":"371.6","Cell RNA - hTERT-RPE1 [nTPM]":"69.1","Cell RNA - HUVEC TERT2 [nTPM]":"73.3","Cell RNA - JURKAT [nTPM]":"9.5","Cell RNA - K-562 [nTPM]":"12.6","Cell RNA - Karpas-707 [nTPM]":"38.2","Cell RNA - LHCN-M2 [nTPM]":"113.9","Cell RNA - MCF7 [nTPM]":"20.2","Cell RNA - MOLT-4 [nTPM]":"5.1","Cell RNA - NB-4 [nTPM]":"6.8","Cell RNA - NTERA-2 [nTPM]":"27.7","Cell RNA - OE19 [nTPM]":"35.6","Cell RNA - PC-3 [nTPM]":"21.9","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"28.8","Cell RNA - RPMI-8226 [nTPM]":"16.5","Cell RNA - RPTEC TERT1 [nTPM]":"118.8","Cell RNA - RT4 [nTPM]":"83.0","Cell RNA - SCLC-21H [nTPM]":"47.2","Cell RNA - SH-SY5Y [nTPM]":"37.8","Cell RNA - SiHa [nTPM]":"32.7","Cell RNA - SK-BR-3 [nTPM]":"11.7","Cell RNA - SK-MEL-30 [nTPM]":"64.1","Cell RNA - SuSa [nTPM]":"67.7","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"27.2","Cell RNA - TIME [nTPM]":"176.5","Cell RNA - U-138 MG [nTPM]":"77.3","Cell RNA - U-2 OS [nTPM]":"55.9","Cell RNA - U-2197 [nTPM]":"37.0","Cell RNA - U-251 MG [nTPM]":"68.9","Cell RNA - U-266\/70 [nTPM]":"39.6","Cell RNA - U-266\/84 [nTPM]":"28.6","Cell RNA - U-698 [nTPM]":"5.0","Cell RNA - U-87 MG [nTPM]":"55.8","Cell RNA - U-937 [nTPM]":"8.8","Cell RNA - WM-115 [nTPM]":"40.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"206.5","Brain RNA - basal ganglia [nTPM]":"275.8","Brain RNA - cerebellum [nTPM]":"240.6","Brain RNA - cerebral cortex [nTPM]":"221.9","Brain RNA - hippocampal formation [nTPM]":"194.6","Brain RNA - hypothalamus [nTPM]":"230.7","Brain RNA - medulla oblongata [nTPM]":"258.1","Brain RNA - midbrain [nTPM]":"250.4","Brain RNA - pons [nTPM]":"263.4","Brain RNA - spinal cord [nTPM]":"209.1","Brain RNA - thalamus [nTPM]":"243.3","Brain RNA - white matter [nTPM]":"325.4","Single Cell Type RNA - Adipocytes [nTPM]":"193.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"336.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.8","Single Cell Type RNA - Astrocytes [nTPM]":"1048.7","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2368.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1651.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"250.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3008.4","Single Cell Type RNA - Bipolar cells [nTPM]":"673.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"81.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"301.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"862.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"77.2","Single Cell Type RNA - Club cells [nTPM]":"161.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"1401.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"61.5","Single Cell Type RNA - dendritic cells [nTPM]":"7.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"357.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"204.3","Single Cell Type RNA - Early spermatids [nTPM]":"53.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"133.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"218.4","Single Cell Type RNA - Endothelial cells [nTPM]":"122.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.9","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"550.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"66.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.6","Single Cell Type RNA - Fibroblasts [nTPM]":"212.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"71.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"166.8","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"478.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"60.7","Single Cell Type RNA - Hepatocytes [nTPM]":"80.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.8","Single Cell Type RNA - Horizontal cells [nTPM]":"307.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"591.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"100.3","Single Cell Type RNA - Ionocytes [nTPM]":"118.0","Single Cell Type RNA - Kupffer cells [nTPM]":"74.2","Single Cell Type RNA - Langerhans cells [nTPM]":"124.6","Single Cell Type RNA - Late spermatids [nTPM]":"15.5","Single Cell Type RNA - Leydig cells [nTPM]":"133.3","Single Cell Type RNA - Macrophages [nTPM]":"56.6","Single Cell Type RNA - Melanocytes [nTPM]":"215.3","Single Cell Type RNA - Microglial cells [nTPM]":"215.5","Single Cell Type RNA - monocytes [nTPM]":"46.6","Single Cell Type RNA - Muller glia cells [nTPM]":"200.8","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"630.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1410.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"194.1","Single Cell Type RNA - Paneth cells [nTPM]":"283.0","Single Cell Type RNA - Peritubular cells [nTPM]":"152.4","Single Cell Type RNA - Plasma cells [nTPM]":"27.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"229.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"124.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"52.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"122.6","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"381.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"196.6","Single Cell Type RNA - Spermatocytes [nTPM]":"20.0","Single Cell Type RNA - Spermatogonia [nTPM]":"13.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"298.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"857.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.5","Single Cell Type RNA - T-cells [nTPM]":"19.7","Single Cell Type RNA - Theca cells [nTPM]":"30.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"48.1","Single Cell Type RNA - Urothelial cells [nTPM]":"142.8"},{"Gene":"DSTYK","Gene synonym":["DustyPK","KIAA0472","RIP5","RIPK5","SPG23"],"Ensembl":"ENSG00000133059","Gene description":"Dual serine\/threonine and tyrosine protein kinase","Uniprot":["Q6XUX3"],"Chromosome":"1","Position":"205142505-205211702","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"89.2","Melanocytes":"90.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044140"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044140":"AB_10965031"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.73e-5"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"11.5","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"11.1","Tissue RNA - bone marrow [nTPM]":"19.2","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"7.9","Tissue RNA - epididymis [nTPM]":"5.8","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"4.9","Tissue RNA - hippocampal formation [nTPM]":"11.8","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"6.1","Tissue RNA - lymph node [nTPM]":"4.0","Tissue RNA - medulla oblongata [nTPM]":"13.5","Tissue RNA - midbrain [nTPM]":"10.7","Tissue RNA - ovary [nTPM]":"11.1","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"6.0","Tissue RNA - pons [nTPM]":"13.7","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"13.5","Tissue RNA - salivary gland [nTPM]":"4.4","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"12.0","Tissue RNA - small intestine [nTPM]":"4.1","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"4.2","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"11.5","Tissue RNA - thymus [nTPM]":"6.2","Tissue RNA - thyroid gland [nTPM]":"6.8","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"4.5","Tissue RNA - urinary bladder [nTPM]":"5.2","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"13.5","Cell RNA - A-431 [nTPM]":"9.9","Cell RNA - A549 [nTPM]":"6.3","Cell RNA - AF22 [nTPM]":"6.6","Cell RNA - AN3-CA [nTPM]":"8.1","Cell RNA - ASC diff [nTPM]":"9.5","Cell RNA - ASC TERT1 [nTPM]":"15.9","Cell RNA - BEWO [nTPM]":"4.7","Cell RNA - BJ [nTPM]":"12.0","Cell RNA - BJ hTERT+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.4","Cell RNA - CACO-2 [nTPM]":"2.9","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"20.6","Cell RNA - GAMG [nTPM]":"6.9","Cell RNA - HaCaT [nTPM]":"6.9","Cell RNA - HAP1 [nTPM]":"7.3","Cell RNA - HBEC3-KT [nTPM]":"7.8","Cell RNA - HBF TERT88 [nTPM]":"12.4","Cell RNA - HDLM-2 [nTPM]":"3.5","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"13.3","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"3.1","Cell RNA - HHSteC [nTPM]":"8.5","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"9.4","Cell RNA - hTCEpi [nTPM]":"11.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.7","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"14.7","Cell RNA - HUVEC TERT2 [nTPM]":"9.2","Cell RNA - JURKAT [nTPM]":"5.2","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"10.0","Cell RNA - MCF7 [nTPM]":"6.8","Cell RNA - MOLT-4 [nTPM]":"2.9","Cell RNA - NB-4 [nTPM]":"3.3","Cell RNA - NTERA-2 [nTPM]":"7.2","Cell RNA - OE19 [nTPM]":"1.8","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"2.6","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"6.5","Cell RNA - RPTEC TERT1 [nTPM]":"8.4","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"10.3","Cell RNA - SK-BR-3 [nTPM]":"10.5","Cell RNA - SK-MEL-30 [nTPM]":"34.5","Cell RNA - SuSa [nTPM]":"7.7","Cell RNA - T-47d [nTPM]":"7.8","Cell RNA - THP-1 [nTPM]":"4.9","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"7.7","Cell RNA - U-2 OS [nTPM]":"7.7","Cell RNA - U-2197 [nTPM]":"11.8","Cell RNA - U-251 MG [nTPM]":"8.2","Cell RNA - U-266\/70 [nTPM]":"4.8","Cell RNA - U-266\/84 [nTPM]":"3.7","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"9.0","Cell RNA - U-937 [nTPM]":"5.1","Cell RNA - WM-115 [nTPM]":"28.2","Blood RNA - basophil [nTPM]":"8.1","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"3.6","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"2.3","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"11.5","Brain RNA - basal ganglia [nTPM]":"11.1","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"11.8","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"13.5","Brain RNA - midbrain [nTPM]":"10.7","Brain RNA - pons [nTPM]":"13.7","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"11.5","Brain RNA - white matter [nTPM]":"13.5","Single Cell Type RNA - Adipocytes [nTPM]":"15.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.5","Single Cell Type RNA - Astrocytes [nTPM]":"26.4","Single Cell Type RNA - B-cells [nTPM]":"15.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"48.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"15.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - dendritic cells [nTPM]":"15.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.5","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.7","Single Cell Type RNA - Endothelial cells [nTPM]":"16.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.7","Single Cell Type RNA - Erythroid cells [nTPM]":"31.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"19.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.6","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"43.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"6.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"89.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.2","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"23.6","Single Cell Type RNA - Langerhans cells [nTPM]":"15.6","Single Cell Type RNA - Late spermatids [nTPM]":"25.2","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"11.4","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"20.6","Single Cell Type RNA - Muller glia cells [nTPM]":"45.1","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.6","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"11.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.4","Single Cell Type RNA - Spermatocytes [nTPM]":"22.3","Single Cell Type RNA - Spermatogonia [nTPM]":"13.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"15.1","Single Cell Type RNA - Theca cells [nTPM]":"27.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.7"},{"Gene":"DYNC1H1","Gene synonym":["CMT2O","DHC1","DNCH1","Dnchc1","DNCL","DNECL","HL-3","p22"],"Ensembl":"ENSG00000197102","Gene description":"Dynein cytoplasmic 1 heavy chain 1","Uniprot":["Q14204"],"Chromosome":"14","Position":"101964573-102056443","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","Transport"],"Molecular function":["Motor protein"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Mental retardation","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003742","CAB010443"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"490000","Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB010443":"AB_2093483","HPA003742":"AB_1078713"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.09e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Tissue RNA - adipose tissue [nTPM]":"22.4","Tissue RNA - adrenal gland [nTPM]":"19.3","Tissue RNA - amygdala [nTPM]":"7.8","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"9.2","Tissue RNA - breast [nTPM]":"18.2","Tissue RNA - cerebellum [nTPM]":"16.1","Tissue RNA - cerebral cortex [nTPM]":"10.9","Tissue RNA - cervix [nTPM]":"17.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"29.1","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"24.6","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"18.5","Tissue RNA - fallopian tube [nTPM]":"17.5","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"29.7","Tissue RNA - hippocampal formation [nTPM]":"9.2","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"9.4","Tissue RNA - lung [nTPM]":"19.9","Tissue RNA - lymph node [nTPM]":"4.4","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"4.3","Tissue RNA - ovary [nTPM]":"21.0","Tissue RNA - pancreas [nTPM]":"15.8","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"20.9","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"9.0","Tissue RNA - prostate [nTPM]":"14.5","Tissue RNA - rectum [nTPM]":"3.1","Tissue RNA - retina [nTPM]":"13.2","Tissue RNA - salivary gland [nTPM]":"19.9","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"53.1","Tissue RNA - skin 1 [nTPM]":"27.6","Tissue RNA - small intestine [nTPM]":"19.2","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"14.2","Tissue RNA - stomach 1 [nTPM]":"19.7","Tissue RNA - testis [nTPM]":"13.0","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"17.6","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"23.4","Tissue RNA - vagina [nTPM]":"18.0","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"3.3","Cell RNA - A549 [nTPM]":"6.6","Cell RNA - AF22 [nTPM]":"5.0","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"5.0","Cell RNA - BEWO [nTPM]":"3.2","Cell RNA - BJ [nTPM]":"3.0","Cell RNA - BJ hTERT+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.5","Cell RNA - CACO-2 [nTPM]":"2.6","Cell RNA - CAPAN-2 [nTPM]":"4.5","Cell RNA - Daudi [nTPM]":"4.2","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"5.4","Cell RNA - GAMG [nTPM]":"4.9","Cell RNA - HaCaT [nTPM]":"4.0","Cell RNA - HAP1 [nTPM]":"8.2","Cell RNA - HBEC3-KT [nTPM]":"5.3","Cell RNA - HBF TERT88 [nTPM]":"3.6","Cell RNA - HDLM-2 [nTPM]":"3.4","Cell RNA - HEK 293 [nTPM]":"3.5","Cell RNA - HEL [nTPM]":"4.1","Cell RNA - HeLa [nTPM]":"15.1","Cell RNA - Hep G2 [nTPM]":"3.3","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"3.6","Cell RNA - HMC-1 [nTPM]":"6.4","Cell RNA - HSkMC [nTPM]":"6.4","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.1","Cell RNA - hTERT-HME1 [nTPM]":"4.9","Cell RNA - hTERT-RPE1 [nTPM]":"3.2","Cell RNA - HUVEC TERT2 [nTPM]":"3.9","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"3.0","Cell RNA - Karpas-707 [nTPM]":"8.9","Cell RNA - LHCN-M2 [nTPM]":"4.5","Cell RNA - MCF7 [nTPM]":"4.2","Cell RNA - MOLT-4 [nTPM]":"5.6","Cell RNA - NB-4 [nTPM]":"4.1","Cell RNA - NTERA-2 [nTPM]":"5.1","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"10.2","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"3.3","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"5.2","Cell RNA - RT4 [nTPM]":"7.6","Cell RNA - SCLC-21H [nTPM]":"8.4","Cell RNA - SH-SY5Y [nTPM]":"2.8","Cell RNA - SiHa [nTPM]":"3.2","Cell RNA - SK-BR-3 [nTPM]":"2.2","Cell RNA - SK-MEL-30 [nTPM]":"3.4","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"2.5","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"11.5","Cell RNA - U-138 MG [nTPM]":"6.8","Cell RNA - U-2 OS [nTPM]":"4.1","Cell RNA - U-2197 [nTPM]":"11.5","Cell RNA - U-251 MG [nTPM]":"5.1","Cell RNA - U-266\/70 [nTPM]":"4.3","Cell RNA - U-266\/84 [nTPM]":"7.6","Cell RNA - U-698 [nTPM]":"4.9","Cell RNA - U-87 MG [nTPM]":"9.1","Cell RNA - U-937 [nTPM]":"2.9","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"7.8","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"16.1","Brain RNA - cerebral cortex [nTPM]":"10.9","Brain RNA - hippocampal formation [nTPM]":"9.2","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"4.3","Brain RNA - pons [nTPM]":"9.0","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"102.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"125.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"84.7","Single Cell Type RNA - Astrocytes [nTPM]":"83.9","Single Cell Type RNA - B-cells [nTPM]":"55.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"46.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"126.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"63.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"55.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"182.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"89.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"77.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"139.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"49.6","Single Cell Type RNA - dendritic cells [nTPM]":"106.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"94.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"112.6","Single Cell Type RNA - Early spermatids [nTPM]":"14.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"123.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"131.0","Single Cell Type RNA - Endothelial cells [nTPM]":"93.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"71.3","Single Cell Type RNA - Erythroid cells [nTPM]":"38.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"127.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"81.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"42.9","Single Cell Type RNA - Fibroblasts [nTPM]":"86.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"86.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"134.6","Single Cell Type RNA - granulocytes [nTPM]":"33.5","Single Cell Type RNA - Granulosa cells [nTPM]":"117.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.1","Single Cell Type RNA - Hepatocytes [nTPM]":"36.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"40.2","Single Cell Type RNA - Horizontal cells [nTPM]":"183.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"131.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"68.0","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"52.7","Single Cell Type RNA - Langerhans cells [nTPM]":"123.6","Single Cell Type RNA - Late spermatids [nTPM]":"16.8","Single Cell Type RNA - Leydig cells [nTPM]":"70.5","Single Cell Type RNA - Macrophages [nTPM]":"90.7","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"99.2","Single Cell Type RNA - Muller glia cells [nTPM]":"63.3","Single Cell Type RNA - NK-cells [nTPM]":"73.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"51.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"93.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"131.3","Single Cell Type RNA - Paneth cells [nTPM]":"73.6","Single Cell Type RNA - Peritubular cells [nTPM]":"71.5","Single Cell Type RNA - Plasma cells [nTPM]":"100.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"47.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"82.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"90.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"115.4","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"81.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"106.1","Single Cell Type RNA - Spermatocytes [nTPM]":"87.1","Single Cell Type RNA - Spermatogonia [nTPM]":"72.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"59.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"64.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.4","Single Cell Type RNA - T-cells [nTPM]":"91.3","Single Cell Type RNA - Theca cells [nTPM]":"86.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"64.4","Single Cell Type RNA - Urothelial cells [nTPM]":"46.5"},{"Gene":"EDN3","Gene synonym":["ET3"],"Ensembl":"ENSG00000124205","Gene description":"Endothelin 3","Uniprot":["P14138"],"Chromosome":"20","Position":"59300443-59325992","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Vasoactive","Vasoconstrictor"],"Disease involvement":["Deafness","Disease variant","Hirschsprung disease","Waardenburg syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"53.1","salivary gland":"68.3","vagina":"106.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"99.6","Distal enterocytes":"86.6","Paneth cells":"72.4","Proximal enterocytes":"93.0","Skeletal myocytes":"110.0","Squamous epithelial cells":"69.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":30900,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"5.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"5.9","Tissue RNA - cervix [nTPM]":"53.1","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"20.2","Tissue RNA - duodenum [nTPM]":"42.0","Tissue RNA - endometrium 1 [nTPM]":"5.2","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"20.6","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"8.8","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"44.7","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"18.8","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"68.3","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"1.9","Tissue RNA - small intestine [nTPM]":"40.6","Tissue RNA - smooth muscle [nTPM]":"3.0","Tissue RNA - spinal cord [nTPM]":"5.0","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"11.2","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"24.2","Tissue RNA - tongue [nTPM]":"2.4","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"106.5","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"5.1","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"5.9","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"5.0","Brain RNA - thalamus [nTPM]":"11.2","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"99.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"86.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"72.4","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"93.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"110.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"69.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"EEF1A2","Gene synonym":["EEF1AL","HS1","STN","STNL"],"Ensembl":"ENSG00000101210","Gene description":"Eukaryotic translation elongation factor 1 alpha 2","Uniprot":["Q05639"],"Chromosome":"20","Position":"63488013-63499239","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Elongation factor"],"Disease involvement":["Autism spectrum disorder","Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"1638.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"130.8","Cardiomyocytes":"125.5","Horizontal cells":"269.2","Rod photoreceptor cells":"50.9","Skeletal myocytes":"49.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"347.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"240.0","MCF7":"405.9","SCLC-21H":"187.0","T-47d":"157.2","U-2 OS":"202.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034019","HPA051759","HPA053862","HPA056990"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB034019":"AB_1562672","HPA051759":"AB_2681595","HPA053862":"AB_2797248","HPA056990":"AB_2683302"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.11e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"32.7","Tissue RNA - amygdala [nTPM]":"59.3","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"81.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"17.1","Tissue RNA - cerebral cortex [nTPM]":"347.2","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"9.7","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"358.0","Tissue RNA - hippocampal formation [nTPM]":"73.4","Tissue RNA - hypothalamus [nTPM]":"97.3","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"3.0","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"95.0","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"16.2","Tissue RNA - pituitary gland [nTPM]":"111.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"76.3","Tissue RNA - prostate [nTPM]":"9.6","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"37.2","Tissue RNA - salivary gland [nTPM]":"19.5","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"1638.0","Tissue RNA - skin 1 [nTPM]":"6.8","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"8.5","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"30.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"320.7","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"2.2","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"125.0","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"71.0","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"16.8","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"7.9","Cell RNA - BJ [nTPM]":"10.0","Cell RNA - BJ hTERT+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.3","Cell RNA - CACO-2 [nTPM]":"9.8","Cell RNA - CAPAN-2 [nTPM]":"41.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"110.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"13.4","Cell RNA - HaCaT [nTPM]":"38.8","Cell RNA - HAP1 [nTPM]":"240.0","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"115.9","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"13.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"24.1","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"2.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"13.4","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"3.4","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"405.9","Cell RNA - MOLT-4 [nTPM]":"1.4","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"11.4","Cell RNA - OE19 [nTPM]":"95.6","Cell RNA - PC-3 [nTPM]":"96.5","Cell RNA - REH [nTPM]":"8.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"10.2","Cell RNA - RPTEC TERT1 [nTPM]":"2.4","Cell RNA - RT4 [nTPM]":"3.9","Cell RNA - SCLC-21H [nTPM]":"187.0","Cell RNA - SH-SY5Y [nTPM]":"89.9","Cell RNA - SiHa [nTPM]":"90.0","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"2.2","Cell RNA - T-47d [nTPM]":"157.2","Cell RNA - THP-1 [nTPM]":"3.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"202.9","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"1.8","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"1.4","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"1.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"59.3","Brain RNA - basal ganglia [nTPM]":"81.3","Brain RNA - cerebellum [nTPM]":"17.1","Brain RNA - cerebral cortex [nTPM]":"347.2","Brain RNA - hippocampal formation [nTPM]":"73.4","Brain RNA - hypothalamus [nTPM]":"97.3","Brain RNA - medulla oblongata [nTPM]":"95.0","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"76.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"30.7","Brain RNA - white matter [nTPM]":"125.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"130.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"125.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"269.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"49.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"EEF2","Gene synonym":["EEF-2","EF2"],"Ensembl":"ENSG00000167658","Gene description":"Eukaryotic translation elongation factor 2","Uniprot":["P13639"],"Chromosome":"19","Position":"3976056-3985463","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Elongation factor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007795","HPA040534","HPA057351"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB007795":"AB_598149","HPA040534":"AB_2677024","HPA057351":"AB_2683417"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.81e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"1022.6","Tissue RNA - adrenal gland [nTPM]":"1037.0","Tissue RNA - amygdala [nTPM]":"771.8","Tissue RNA - appendix [nTPM]":"507.3","Tissue RNA - basal ganglia [nTPM]":"755.2","Tissue RNA - bone marrow [nTPM]":"920.3","Tissue RNA - breast [nTPM]":"946.7","Tissue RNA - cerebellum [nTPM]":"737.2","Tissue RNA - cerebral cortex [nTPM]":"1059.6","Tissue RNA - cervix [nTPM]":"966.7","Tissue RNA - choroid plexus [nTPM]":"807.6","Tissue RNA - colon [nTPM]":"1122.4","Tissue RNA - duodenum [nTPM]":"821.4","Tissue RNA - endometrium 1 [nTPM]":"887.6","Tissue RNA - epididymis [nTPM]":"563.7","Tissue RNA - esophagus [nTPM]":"1062.3","Tissue RNA - fallopian tube [nTPM]":"857.3","Tissue RNA - gallbladder [nTPM]":"501.2","Tissue RNA - heart muscle [nTPM]":"1396.6","Tissue RNA - hippocampal formation [nTPM]":"740.9","Tissue RNA - hypothalamus [nTPM]":"729.1","Tissue RNA - kidney [nTPM]":"843.2","Tissue RNA - liver [nTPM]":"1152.9","Tissue RNA - lung [nTPM]":"666.9","Tissue RNA - lymph node [nTPM]":"685.4","Tissue RNA - medulla oblongata [nTPM]":"775.4","Tissue RNA - midbrain [nTPM]":"769.6","Tissue RNA - ovary [nTPM]":"1627.6","Tissue RNA - pancreas [nTPM]":"3194.1","Tissue RNA - parathyroid gland [nTPM]":"494.0","Tissue RNA - pituitary gland [nTPM]":"838.0","Tissue RNA - placenta [nTPM]":"386.2","Tissue RNA - pons [nTPM]":"782.3","Tissue RNA - prostate [nTPM]":"819.2","Tissue RNA - rectum [nTPM]":"344.5","Tissue RNA - retina [nTPM]":"224.7","Tissue RNA - salivary gland [nTPM]":"1276.4","Tissue RNA - seminal vesicle [nTPM]":"500.3","Tissue RNA - skeletal muscle [nTPM]":"2322.6","Tissue RNA - skin 1 [nTPM]":"1142.7","Tissue RNA - small intestine [nTPM]":"798.9","Tissue RNA - smooth muscle [nTPM]":"385.4","Tissue RNA - spinal cord [nTPM]":"758.3","Tissue RNA - spleen [nTPM]":"721.6","Tissue RNA - stomach 1 [nTPM]":"1266.6","Tissue RNA - testis [nTPM]":"490.5","Tissue RNA - thalamus [nTPM]":"762.7","Tissue RNA - thymus [nTPM]":"541.0","Tissue RNA - thyroid gland [nTPM]":"793.6","Tissue RNA - tongue [nTPM]":"1112.4","Tissue RNA - tonsil [nTPM]":"499.0","Tissue RNA - urinary bladder [nTPM]":"927.8","Tissue RNA - vagina [nTPM]":"797.7","Tissue RNA - white matter [nTPM]":"745.1","Cell RNA - A-431 [nTPM]":"1456.8","Cell RNA - A549 [nTPM]":"1018.4","Cell RNA - AF22 [nTPM]":"579.3","Cell RNA - AN3-CA [nTPM]":"1539.4","Cell RNA - ASC diff [nTPM]":"1515.6","Cell RNA - ASC TERT1 [nTPM]":"2706.7","Cell RNA - BEWO [nTPM]":"830.9","Cell RNA - BJ [nTPM]":"1110.4","Cell RNA - BJ hTERT+ [nTPM]":"1479.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1036.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1012.7","Cell RNA - CACO-2 [nTPM]":"1618.1","Cell RNA - CAPAN-2 [nTPM]":"652.7","Cell RNA - Daudi [nTPM]":"3000.6","Cell RNA - EFO-21 [nTPM]":"644.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1032.3","Cell RNA - GAMG [nTPM]":"461.1","Cell RNA - HaCaT [nTPM]":"1069.8","Cell RNA - HAP1 [nTPM]":"919.4","Cell RNA - HBEC3-KT [nTPM]":"1719.4","Cell RNA - HBF TERT88 [nTPM]":"544.2","Cell RNA - HDLM-2 [nTPM]":"755.0","Cell RNA - HEK 293 [nTPM]":"1533.0","Cell RNA - HEL [nTPM]":"768.5","Cell RNA - HeLa [nTPM]":"919.9","Cell RNA - Hep G2 [nTPM]":"1677.0","Cell RNA - HHSteC [nTPM]":"2204.8","Cell RNA - HL-60 [nTPM]":"1668.0","Cell RNA - HMC-1 [nTPM]":"1277.6","Cell RNA - HSkMC [nTPM]":"3515.5","Cell RNA - hTCEpi [nTPM]":"1777.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"916.0","Cell RNA - hTERT-HME1 [nTPM]":"1404.1","Cell RNA - hTERT-RPE1 [nTPM]":"1497.5","Cell RNA - HUVEC TERT2 [nTPM]":"1086.6","Cell RNA - JURKAT [nTPM]":"1434.4","Cell RNA - K-562 [nTPM]":"1526.7","Cell RNA - Karpas-707 [nTPM]":"2145.4","Cell RNA - LHCN-M2 [nTPM]":"642.1","Cell RNA - MCF7 [nTPM]":"2095.7","Cell RNA - MOLT-4 [nTPM]":"1510.1","Cell RNA - NB-4 [nTPM]":"1266.3","Cell RNA - NTERA-2 [nTPM]":"1537.0","Cell RNA - OE19 [nTPM]":"518.3","Cell RNA - PC-3 [nTPM]":"1015.7","Cell RNA - REH [nTPM]":"1654.2","Cell RNA - RH-30 [nTPM]":"860.3","Cell RNA - RPMI-8226 [nTPM]":"1938.3","Cell RNA - RPTEC TERT1 [nTPM]":"871.2","Cell RNA - RT4 [nTPM]":"1270.2","Cell RNA - SCLC-21H [nTPM]":"1575.4","Cell RNA - SH-SY5Y [nTPM]":"1466.4","Cell RNA - SiHa [nTPM]":"699.0","Cell RNA - SK-BR-3 [nTPM]":"1377.1","Cell RNA - SK-MEL-30 [nTPM]":"2058.3","Cell RNA - SuSa [nTPM]":"543.1","Cell RNA - T-47d [nTPM]":"1344.7","Cell RNA - THP-1 [nTPM]":"1992.7","Cell RNA - TIME [nTPM]":"1321.8","Cell RNA - U-138 MG [nTPM]":"738.2","Cell RNA - U-2 OS [nTPM]":"765.7","Cell RNA - U-2197 [nTPM]":"1521.4","Cell RNA - U-251 MG [nTPM]":"1738.7","Cell RNA - U-266\/70 [nTPM]":"2276.4","Cell RNA - U-266\/84 [nTPM]":"1644.3","Cell RNA - U-698 [nTPM]":"1485.3","Cell RNA - U-87 MG [nTPM]":"1100.4","Cell RNA - U-937 [nTPM]":"2065.8","Cell RNA - WM-115 [nTPM]":"986.6","Blood RNA - basophil [nTPM]":"81.2","Blood RNA - classical monocyte [nTPM]":"455.7","Blood RNA - eosinophil [nTPM]":"64.1","Blood RNA - gdT-cell [nTPM]":"259.8","Blood RNA - intermediate monocyte [nTPM]":"333.1","Blood RNA - MAIT T-cell [nTPM]":"460.2","Blood RNA - memory B-cell [nTPM]":"578.5","Blood RNA - memory CD4 T-cell [nTPM]":"453.0","Blood RNA - memory CD8 T-cell [nTPM]":"344.6","Blood RNA - myeloid DC [nTPM]":"430.7","Blood RNA - naive B-cell [nTPM]":"478.1","Blood RNA - naive CD4 T-cell [nTPM]":"497.2","Blood RNA - naive CD8 T-cell [nTPM]":"404.1","Blood RNA - neutrophil [nTPM]":"43.1","Blood RNA - NK-cell [nTPM]":"355.3","Blood RNA - non-classical monocyte [nTPM]":"342.1","Blood RNA - plasmacytoid DC [nTPM]":"358.7","Blood RNA - T-reg [nTPM]":"429.4","Blood RNA - total PBMC [nTPM]":"756.5","Brain RNA - amygdala [nTPM]":"771.8","Brain RNA - basal ganglia [nTPM]":"755.2","Brain RNA - cerebellum [nTPM]":"737.2","Brain RNA - cerebral cortex [nTPM]":"1059.6","Brain RNA - hippocampal formation [nTPM]":"740.9","Brain RNA - hypothalamus [nTPM]":"729.1","Brain RNA - medulla oblongata [nTPM]":"775.4","Brain RNA - midbrain [nTPM]":"769.6","Brain RNA - pons [nTPM]":"782.3","Brain RNA - spinal cord [nTPM]":"758.3","Brain RNA - thalamus [nTPM]":"762.7","Brain RNA - white matter [nTPM]":"745.1","Single Cell Type RNA - Adipocytes [nTPM]":"323.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"221.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"392.2","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"1125.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1321.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1071.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"754.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1269.7","Single Cell Type RNA - Bipolar cells [nTPM]":"212.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"981.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"694.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"627.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"597.7","Single Cell Type RNA - Club cells [nTPM]":"448.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"255.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"77.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"958.1","Single Cell Type RNA - dendritic cells [nTPM]":"535.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"556.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"986.1","Single Cell Type RNA - Ductal cells [nTPM]":"716.0","Single Cell Type RNA - Early spermatids [nTPM]":"799.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"318.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"675.4","Single Cell Type RNA - Endothelial cells [nTPM]":"568.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"744.2","Single Cell Type RNA - Erythroid cells [nTPM]":"934.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1816.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1305.0","Single Cell Type RNA - Fibroblasts [nTPM]":"679.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"619.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"428.5","Single Cell Type RNA - granulocytes [nTPM]":"373.4","Single Cell Type RNA - Granulosa cells [nTPM]":"596.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"656.8","Single Cell Type RNA - Hepatocytes [nTPM]":"690.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"610.1","Single Cell Type RNA - Horizontal cells [nTPM]":"203.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"982.1","Single Cell Type RNA - Ionocytes [nTPM]":"411.0","Single Cell Type RNA - Kupffer cells [nTPM]":"885.4","Single Cell Type RNA - Langerhans cells [nTPM]":"859.5","Single Cell Type RNA - Late spermatids [nTPM]":"1195.6","Single Cell Type RNA - Leydig cells [nTPM]":"1008.4","Single Cell Type RNA - Macrophages [nTPM]":"514.2","Single Cell Type RNA - Melanocytes [nTPM]":"645.7","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"907.5","Single Cell Type RNA - Muller glia cells [nTPM]":"429.1","Single Cell Type RNA - NK-cells [nTPM]":"614.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"868.2","Single Cell Type RNA - Paneth cells [nTPM]":"815.5","Single Cell Type RNA - Peritubular cells [nTPM]":"832.8","Single Cell Type RNA - Plasma cells [nTPM]":"992.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1010.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1562.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1078.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"194.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"134.1","Single Cell Type RNA - Sertoli cells [nTPM]":"585.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"797.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"697.3","Single Cell Type RNA - Spermatocytes [nTPM]":"371.5","Single Cell Type RNA - Spermatogonia [nTPM]":"308.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1343.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1347.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1243.1","Single Cell Type RNA - T-cells [nTPM]":"727.1","Single Cell Type RNA - Theca cells [nTPM]":"1044.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1168.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1051.6"},{"Gene":"EFEMP1","Gene synonym":["DHRD","FBLN3","FBNL","MTLV","S1-5"],"Ensembl":"ENSG00000115380","Gene description":"EGF containing fibulin extracellular matrix protein 1","Uniprot":["Q12805"],"Chromosome":"2","Position":"55865967-55924139","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"367.7","Cytotrophoblasts":"1365.8","Fibroblasts":"309.7","Syncytiotrophoblasts":"889.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"94.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HSkMC":"953.6","hTERT-RPE1":"2226.5","HUVEC TERT2":"4270.9","TIME":"3554.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016368","HPA049806","HPA070841","HPA071588"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB016368":"AB_2277777","HPA049806":null,"HPA070841":"AB_2686319","HPA071588":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.72e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.89e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.68e-5"},"Tissue RNA - adipose tissue [nTPM]":"240.5","Tissue RNA - adrenal gland [nTPM]":"55.7","Tissue RNA - amygdala [nTPM]":"57.0","Tissue RNA - appendix [nTPM]":"57.2","Tissue RNA - basal ganglia [nTPM]":"82.8","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"115.3","Tissue RNA - cerebellum [nTPM]":"57.1","Tissue RNA - cerebral cortex [nTPM]":"88.8","Tissue RNA - cervix [nTPM]":"54.9","Tissue RNA - choroid plexus [nTPM]":"180.7","Tissue RNA - colon [nTPM]":"74.6","Tissue RNA - duodenum [nTPM]":"22.5","Tissue RNA - endometrium 1 [nTPM]":"73.2","Tissue RNA - epididymis [nTPM]":"128.4","Tissue RNA - esophagus [nTPM]":"51.5","Tissue RNA - fallopian tube [nTPM]":"134.8","Tissue RNA - gallbladder [nTPM]":"140.4","Tissue RNA - heart muscle [nTPM]":"187.8","Tissue RNA - hippocampal formation [nTPM]":"47.5","Tissue RNA - hypothalamus [nTPM]":"75.6","Tissue RNA - kidney [nTPM]":"57.4","Tissue RNA - liver [nTPM]":"12.9","Tissue RNA - lung [nTPM]":"150.1","Tissue RNA - lymph node [nTPM]":"27.2","Tissue RNA - medulla oblongata [nTPM]":"80.8","Tissue RNA - midbrain [nTPM]":"121.1","Tissue RNA - ovary [nTPM]":"175.1","Tissue RNA - pancreas [nTPM]":"29.2","Tissue RNA - parathyroid gland [nTPM]":"17.6","Tissue RNA - pituitary gland [nTPM]":"22.6","Tissue RNA - placenta [nTPM]":"329.7","Tissue RNA - pons [nTPM]":"65.5","Tissue RNA - prostate [nTPM]":"58.4","Tissue RNA - rectum [nTPM]":"91.0","Tissue RNA - retina [nTPM]":"42.8","Tissue RNA - salivary gland [nTPM]":"87.7","Tissue RNA - seminal vesicle [nTPM]":"161.2","Tissue RNA - skeletal muscle [nTPM]":"14.7","Tissue RNA - skin 1 [nTPM]":"55.2","Tissue RNA - small intestine [nTPM]":"45.3","Tissue RNA - smooth muscle [nTPM]":"93.5","Tissue RNA - spinal cord [nTPM]":"72.2","Tissue RNA - spleen [nTPM]":"42.4","Tissue RNA - stomach 1 [nTPM]":"46.9","Tissue RNA - testis [nTPM]":"8.0","Tissue RNA - thalamus [nTPM]":"71.0","Tissue RNA - thymus [nTPM]":"16.8","Tissue RNA - thyroid gland [nTPM]":"139.1","Tissue RNA - tongue [nTPM]":"93.8","Tissue RNA - tonsil [nTPM]":"21.2","Tissue RNA - urinary bladder [nTPM]":"203.9","Tissue RNA - vagina [nTPM]":"77.3","Tissue RNA - white matter [nTPM]":"71.9","Cell RNA - A-431 [nTPM]":"358.4","Cell RNA - A549 [nTPM]":"3.1","Cell RNA - AF22 [nTPM]":"8.5","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"320.9","Cell RNA - ASC TERT1 [nTPM]":"217.1","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"208.1","Cell RNA - BJ hTERT+ [nTPM]":"233.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"18.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"140.4","Cell RNA - fHDF\/TERT166 [nTPM]":"234.3","Cell RNA - GAMG [nTPM]":"22.1","Cell RNA - HaCaT [nTPM]":"323.4","Cell RNA - HAP1 [nTPM]":"1.6","Cell RNA - HBEC3-KT [nTPM]":"234.6","Cell RNA - HBF TERT88 [nTPM]":"8.9","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"87.4","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"843.2","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"953.6","Cell RNA - hTCEpi [nTPM]":"117.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.9","Cell RNA - hTERT-HME1 [nTPM]":"260.9","Cell RNA - hTERT-RPE1 [nTPM]":"2226.5","Cell RNA - HUVEC TERT2 [nTPM]":"4270.9","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"1.2","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"99.2","Cell RNA - MCF7 [nTPM]":"36.7","Cell RNA - MOLT-4 [nTPM]":"2.6","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"4.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"9.8","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"284.6","Cell RNA - SK-BR-3 [nTPM]":"105.0","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"8.1","Cell RNA - T-47d [nTPM]":"289.8","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"3554.3","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"107.5","Cell RNA - U-2197 [nTPM]":"397.9","Cell RNA - U-251 MG [nTPM]":"138.5","Cell RNA - U-266\/70 [nTPM]":"13.7","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"1.4","Cell RNA - U-87 MG [nTPM]":"73.1","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"6.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"57.0","Brain RNA - basal ganglia [nTPM]":"82.8","Brain RNA - cerebellum [nTPM]":"57.1","Brain RNA - cerebral cortex [nTPM]":"88.8","Brain RNA - hippocampal formation [nTPM]":"47.5","Brain RNA - hypothalamus [nTPM]":"75.6","Brain RNA - medulla oblongata [nTPM]":"80.8","Brain RNA - midbrain [nTPM]":"121.1","Brain RNA - pons [nTPM]":"65.5","Brain RNA - spinal cord [nTPM]":"72.2","Brain RNA - thalamus [nTPM]":"71.0","Brain RNA - white matter [nTPM]":"71.9","Single Cell Type RNA - Adipocytes [nTPM]":"26.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"250.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"109.1","Single Cell Type RNA - Astrocytes [nTPM]":"234.1","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"79.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"79.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"367.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.1","Single Cell Type RNA - Bipolar cells [nTPM]":"2.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"78.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"98.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1365.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"36.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.9","Single Cell Type RNA - Endothelial cells [nTPM]":"73.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"173.0","Single Cell Type RNA - Fibroblasts [nTPM]":"309.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"94.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"33.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"42.6","Single Cell Type RNA - Macrophages [nTPM]":"3.2","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"137.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"88.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"889.6","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"61.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.2"},{"Gene":"EFHC1","Gene synonym":["EJM","EJM1","FLJ10466","POC9","RIB72"],"Ensembl":"ENSG00000096093","Gene description":"EF-hand domain containing 1","Uniprot":["Q5JVL4"],"Chromosome":"6","Position":"52362123-52529886","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"34.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"242.0","Endometrial ciliated cells":"227.5","Respiratory ciliated cells":"529.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"6.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-RPE1":"25.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035307"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035307":"AB_2674561"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"6.6","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"24.6","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"6.7","Tissue RNA - esophagus [nTPM]":"3.3","Tissue RNA - fallopian tube [nTPM]":"34.6","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"4.4","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"2.5","Tissue RNA - lung [nTPM]":"6.5","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"8.1","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"7.3","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"15.5","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"5.2","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"21.7","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"3.4","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"3.4","Tissue RNA - stomach 1 [nTPM]":"4.2","Tissue RNA - testis [nTPM]":"17.6","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"9.3","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"4.7","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"6.7","Cell RNA - A-431 [nTPM]":"3.5","Cell RNA - A549 [nTPM]":"3.9","Cell RNA - AF22 [nTPM]":"9.3","Cell RNA - AN3-CA [nTPM]":"6.4","Cell RNA - ASC diff [nTPM]":"9.0","Cell RNA - ASC TERT1 [nTPM]":"15.3","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"4.1","Cell RNA - BJ hTERT+ [nTPM]":"10.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.6","Cell RNA - CACO-2 [nTPM]":"2.4","Cell RNA - CAPAN-2 [nTPM]":"4.1","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"9.0","Cell RNA - fHDF\/TERT166 [nTPM]":"6.8","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"3.6","Cell RNA - HAP1 [nTPM]":"2.7","Cell RNA - HBEC3-KT [nTPM]":"7.6","Cell RNA - HBF TERT88 [nTPM]":"7.1","Cell RNA - HDLM-2 [nTPM]":"0.8","Cell RNA - HEK 293 [nTPM]":"3.3","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"11.0","Cell RNA - Hep G2 [nTPM]":"3.3","Cell RNA - HHSteC [nTPM]":"6.2","Cell RNA - HL-60 [nTPM]":"1.5","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"7.3","Cell RNA - hTCEpi [nTPM]":"4.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.8","Cell RNA - hTERT-HME1 [nTPM]":"7.2","Cell RNA - hTERT-RPE1 [nTPM]":"25.9","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"1.7","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"2.4","Cell RNA - LHCN-M2 [nTPM]":"8.4","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"1.7","Cell RNA - NB-4 [nTPM]":"2.3","Cell RNA - NTERA-2 [nTPM]":"2.8","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"2.3","Cell RNA - RH-30 [nTPM]":"5.1","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"7.4","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"18.5","Cell RNA - SH-SY5Y [nTPM]":"5.2","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"1.8","Cell RNA - SK-MEL-30 [nTPM]":"8.4","Cell RNA - SuSa [nTPM]":"11.8","Cell RNA - T-47d [nTPM]":"6.5","Cell RNA - THP-1 [nTPM]":"1.6","Cell RNA - TIME [nTPM]":"3.8","Cell RNA - U-138 MG [nTPM]":"4.0","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"1.5","Cell RNA - U-251 MG [nTPM]":"3.2","Cell RNA - U-266\/70 [nTPM]":"2.1","Cell RNA - U-266\/84 [nTPM]":"2.8","Cell RNA - U-698 [nTPM]":"2.7","Cell RNA - U-87 MG [nTPM]":"11.2","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"7.3","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"6.1","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"6.6","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"4.4","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"8.1","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"5.2","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"6.7","Single Cell Type RNA - Adipocytes [nTPM]":"14.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.9","Single Cell Type RNA - Astrocytes [nTPM]":"32.7","Single Cell Type RNA - B-cells [nTPM]":"24.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"49.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"53.5","Single Cell Type RNA - Bipolar cells [nTPM]":"23.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"44.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.6","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.8","Single Cell Type RNA - Early spermatids [nTPM]":"242.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"227.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.0","Single Cell Type RNA - Endothelial cells [nTPM]":"15.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.8","Single Cell Type RNA - Fibroblasts [nTPM]":"27.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.3","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"22.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"5.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.8","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.6","Single Cell Type RNA - Langerhans cells [nTPM]":"14.5","Single Cell Type RNA - Late spermatids [nTPM]":"73.8","Single Cell Type RNA - Leydig cells [nTPM]":"28.3","Single Cell Type RNA - Macrophages [nTPM]":"6.9","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"8.8","Single Cell Type RNA - Muller glia cells [nTPM]":"10.9","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.0","Single Cell Type RNA - Paneth cells [nTPM]":"15.9","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"13.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"529.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"47.5","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.3","Single Cell Type RNA - Spermatocytes [nTPM]":"93.5","Single Cell Type RNA - Spermatogonia [nTPM]":"22.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - T-cells [nTPM]":"9.0","Single Cell Type RNA - Theca cells [nTPM]":"28.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.1","Single Cell Type RNA - Urothelial cells [nTPM]":"27.8"},{"Gene":"EGR2","Gene synonym":["KROX20"],"Ensembl":"ENSG00000122877","Gene description":"Early growth response 2","Uniprot":["P11161"],"Chromosome":"10","Position":"62811996-62919900","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Activator","DNA-binding","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Dejerine-Sottas syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"59.9","thyroid gland":"136.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"55.5","Breast myoepithelial cells":"68.1","Enteroendocrine cells":"73.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"19.7"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"10.2","hippocampal formation":"5.2"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"2.5","non-classical monocyte":"2.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"U-87 MG":"22.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031165"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA031165":"AB_2673768"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.30e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"13.7","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"10.2","Tissue RNA - cervix [nTPM]":"18.5","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"3.3","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"59.9","Tissue RNA - esophagus [nTPM]":"8.8","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"31.9","Tissue RNA - heart muscle [nTPM]":"14.9","Tissue RNA - hippocampal formation [nTPM]":"5.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"15.2","Tissue RNA - lymph node [nTPM]":"14.4","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"9.4","Tissue RNA - pancreas [nTPM]":"4.2","Tissue RNA - parathyroid gland [nTPM]":"7.0","Tissue RNA - pituitary gland [nTPM]":"8.7","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"17.5","Tissue RNA - rectum [nTPM]":"3.7","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"2.9","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"4.6","Tissue RNA - smooth muscle [nTPM]":"16.8","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"4.5","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"26.4","Tissue RNA - thyroid gland [nTPM]":"136.4","Tissue RNA - tongue [nTPM]":"9.1","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"15.7","Tissue RNA - vagina [nTPM]":"1.7","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"1.8","Cell RNA - ASC TERT1 [nTPM]":"2.4","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"3.8","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.3","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.8","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"4.2","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"1.3","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"22.5","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"10.2","Brain RNA - hippocampal formation [nTPM]":"5.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"15.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"14.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"55.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"68.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"9.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"9.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.4","Single Cell Type RNA - Early spermatids [nTPM]":"8.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.0","Single Cell Type RNA - Endothelial cells [nTPM]":"16.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"73.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.6","Single Cell Type RNA - Fibroblasts [nTPM]":"30.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.1","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"2.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.4","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.1","Single Cell Type RNA - Langerhans cells [nTPM]":"39.5","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"40.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"6.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"EIF2AK1","Gene synonym":["HRI","KIAA1369"],"Ensembl":"ENSG00000086232","Gene description":"Eukaryotic translation initiation factor 2 alpha kinase 1","Uniprot":["Q9BQI3"],"Chromosome":"7","Position":"6022247-6059175","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Protein synthesis inhibitor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"219.1","Erythroid cells":"422.0","Syncytiotrophoblasts":"371.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016496","CAB022082","HPA061675"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB022082":null,"HPA016496":"AB_1848057","HPA061675":"AB_2684583"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.2","Tissue RNA - adrenal gland [nTPM]":"39.4","Tissue RNA - amygdala [nTPM]":"28.1","Tissue RNA - appendix [nTPM]":"27.7","Tissue RNA - basal ganglia [nTPM]":"28.9","Tissue RNA - bone marrow [nTPM]":"105.9","Tissue RNA - breast [nTPM]":"35.9","Tissue RNA - cerebellum [nTPM]":"30.6","Tissue RNA - cerebral cortex [nTPM]":"36.1","Tissue RNA - cervix [nTPM]":"29.0","Tissue RNA - choroid plexus [nTPM]":"34.9","Tissue RNA - colon [nTPM]":"48.8","Tissue RNA - duodenum [nTPM]":"37.1","Tissue RNA - endometrium 1 [nTPM]":"25.0","Tissue RNA - epididymis [nTPM]":"37.4","Tissue RNA - esophagus [nTPM]":"30.4","Tissue RNA - fallopian tube [nTPM]":"31.0","Tissue RNA - gallbladder [nTPM]":"23.8","Tissue RNA - heart muscle [nTPM]":"33.8","Tissue RNA - hippocampal formation [nTPM]":"28.1","Tissue RNA - hypothalamus [nTPM]":"30.6","Tissue RNA - kidney [nTPM]":"43.8","Tissue RNA - liver [nTPM]":"65.1","Tissue RNA - lung [nTPM]":"30.3","Tissue RNA - lymph node [nTPM]":"35.2","Tissue RNA - medulla oblongata [nTPM]":"30.5","Tissue RNA - midbrain [nTPM]":"28.9","Tissue RNA - ovary [nTPM]":"29.3","Tissue RNA - pancreas [nTPM]":"44.3","Tissue RNA - parathyroid gland [nTPM]":"78.0","Tissue RNA - pituitary gland [nTPM]":"25.9","Tissue RNA - placenta [nTPM]":"52.3","Tissue RNA - pons [nTPM]":"31.6","Tissue RNA - prostate [nTPM]":"35.0","Tissue RNA - rectum [nTPM]":"47.3","Tissue RNA - retina [nTPM]":"29.0","Tissue RNA - salivary gland [nTPM]":"46.8","Tissue RNA - seminal vesicle [nTPM]":"24.2","Tissue RNA - skeletal muscle [nTPM]":"38.3","Tissue RNA - skin 1 [nTPM]":"33.3","Tissue RNA - small intestine [nTPM]":"37.2","Tissue RNA - smooth muscle [nTPM]":"23.8","Tissue RNA - spinal cord [nTPM]":"29.1","Tissue RNA - spleen [nTPM]":"26.6","Tissue RNA - stomach 1 [nTPM]":"49.1","Tissue RNA - testis [nTPM]":"19.5","Tissue RNA - thalamus [nTPM]":"29.8","Tissue RNA - thymus [nTPM]":"43.6","Tissue RNA - thyroid gland [nTPM]":"39.3","Tissue RNA - tongue [nTPM]":"34.4","Tissue RNA - tonsil [nTPM]":"40.4","Tissue RNA - urinary bladder [nTPM]":"27.2","Tissue RNA - vagina [nTPM]":"22.4","Tissue RNA - white matter [nTPM]":"33.7","Cell RNA - A-431 [nTPM]":"144.5","Cell RNA - A549 [nTPM]":"90.5","Cell RNA - AF22 [nTPM]":"71.2","Cell RNA - AN3-CA [nTPM]":"108.8","Cell RNA - ASC diff [nTPM]":"66.4","Cell RNA - ASC TERT1 [nTPM]":"59.6","Cell RNA - BEWO [nTPM]":"92.4","Cell RNA - BJ [nTPM]":"73.0","Cell RNA - BJ hTERT+ [nTPM]":"66.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"80.8","Cell RNA - CACO-2 [nTPM]":"83.7","Cell RNA - CAPAN-2 [nTPM]":"96.2","Cell RNA - Daudi [nTPM]":"112.5","Cell RNA - EFO-21 [nTPM]":"77.4","Cell RNA - fHDF\/TERT166 [nTPM]":"81.3","Cell RNA - GAMG [nTPM]":"115.5","Cell RNA - HaCaT [nTPM]":"100.4","Cell RNA - HAP1 [nTPM]":"93.1","Cell RNA - HBEC3-KT [nTPM]":"67.1","Cell RNA - HBF TERT88 [nTPM]":"82.2","Cell RNA - HDLM-2 [nTPM]":"69.8","Cell RNA - HEK 293 [nTPM]":"140.3","Cell RNA - HEL [nTPM]":"115.9","Cell RNA - HeLa [nTPM]":"91.6","Cell RNA - Hep G2 [nTPM]":"127.3","Cell RNA - HHSteC [nTPM]":"54.3","Cell RNA - HL-60 [nTPM]":"100.8","Cell RNA - HMC-1 [nTPM]":"102.0","Cell RNA - HSkMC [nTPM]":"48.1","Cell RNA - hTCEpi [nTPM]":"82.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.7","Cell RNA - hTERT-HME1 [nTPM]":"64.9","Cell RNA - hTERT-RPE1 [nTPM]":"67.7","Cell RNA - HUVEC TERT2 [nTPM]":"69.4","Cell RNA - JURKAT [nTPM]":"88.1","Cell RNA - K-562 [nTPM]":"189.0","Cell RNA - Karpas-707 [nTPM]":"106.8","Cell RNA - LHCN-M2 [nTPM]":"61.4","Cell RNA - MCF7 [nTPM]":"146.5","Cell RNA - MOLT-4 [nTPM]":"55.6","Cell RNA - NB-4 [nTPM]":"128.6","Cell RNA - NTERA-2 [nTPM]":"88.5","Cell RNA - OE19 [nTPM]":"84.6","Cell RNA - PC-3 [nTPM]":"99.7","Cell RNA - REH [nTPM]":"120.0","Cell RNA - RH-30 [nTPM]":"74.6","Cell RNA - RPMI-8226 [nTPM]":"134.0","Cell RNA - RPTEC TERT1 [nTPM]":"82.3","Cell RNA - RT4 [nTPM]":"70.3","Cell RNA - SCLC-21H [nTPM]":"87.3","Cell RNA - SH-SY5Y [nTPM]":"156.5","Cell RNA - SiHa [nTPM]":"139.3","Cell RNA - SK-BR-3 [nTPM]":"186.6","Cell RNA - SK-MEL-30 [nTPM]":"63.8","Cell RNA - SuSa [nTPM]":"98.6","Cell RNA - T-47d [nTPM]":"141.0","Cell RNA - THP-1 [nTPM]":"122.4","Cell RNA - TIME [nTPM]":"65.9","Cell RNA - U-138 MG [nTPM]":"37.0","Cell RNA - U-2 OS [nTPM]":"134.2","Cell RNA - U-2197 [nTPM]":"65.3","Cell RNA - U-251 MG [nTPM]":"78.2","Cell RNA - U-266\/70 [nTPM]":"106.5","Cell RNA - U-266\/84 [nTPM]":"114.8","Cell RNA - U-698 [nTPM]":"115.6","Cell RNA - U-87 MG [nTPM]":"73.9","Cell RNA - U-937 [nTPM]":"129.8","Cell RNA - WM-115 [nTPM]":"108.7","Blood RNA - basophil [nTPM]":"11.1","Blood RNA - classical monocyte [nTPM]":"6.9","Blood RNA - eosinophil [nTPM]":"17.3","Blood RNA - gdT-cell [nTPM]":"8.2","Blood RNA - intermediate monocyte [nTPM]":"5.5","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"12.3","Blood RNA - memory CD4 T-cell [nTPM]":"6.5","Blood RNA - memory CD8 T-cell [nTPM]":"9.3","Blood RNA - myeloid DC [nTPM]":"6.9","Blood RNA - naive B-cell [nTPM]":"9.5","Blood RNA - naive CD4 T-cell [nTPM]":"7.5","Blood RNA - naive CD8 T-cell [nTPM]":"6.6","Blood RNA - neutrophil [nTPM]":"3.7","Blood RNA - NK-cell [nTPM]":"10.2","Blood RNA - non-classical monocyte [nTPM]":"6.2","Blood RNA - plasmacytoid DC [nTPM]":"6.0","Blood RNA - T-reg [nTPM]":"8.9","Blood RNA - total PBMC [nTPM]":"4.8","Brain RNA - amygdala [nTPM]":"28.1","Brain RNA - basal ganglia [nTPM]":"28.9","Brain RNA - cerebellum [nTPM]":"30.6","Brain RNA - cerebral cortex [nTPM]":"36.1","Brain RNA - hippocampal formation [nTPM]":"28.1","Brain RNA - hypothalamus [nTPM]":"30.6","Brain RNA - medulla oblongata [nTPM]":"30.5","Brain RNA - midbrain [nTPM]":"28.9","Brain RNA - pons [nTPM]":"31.6","Brain RNA - spinal cord [nTPM]":"29.1","Brain RNA - thalamus [nTPM]":"29.8","Brain RNA - white matter [nTPM]":"33.7","Single Cell Type RNA - Adipocytes [nTPM]":"23.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"43.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"42.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"41.5","Single Cell Type RNA - Bipolar cells [nTPM]":"29.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"52.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"37.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"219.1","Single Cell Type RNA - dendritic cells [nTPM]":"52.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"57.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"66.5","Single Cell Type RNA - Ductal cells [nTPM]":"55.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.3","Single Cell Type RNA - Endothelial cells [nTPM]":"27.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"38.5","Single Cell Type RNA - Erythroid cells [nTPM]":"422.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"82.1","Single Cell Type RNA - Fibroblasts [nTPM]":"29.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"64.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.1","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"44.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"63.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"53.8","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"68.7","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"39.0","Single Cell Type RNA - Langerhans cells [nTPM]":"29.9","Single Cell Type RNA - Late spermatids [nTPM]":"16.1","Single Cell Type RNA - Leydig cells [nTPM]":"34.5","Single Cell Type RNA - Macrophages [nTPM]":"65.2","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"62.8","Single Cell Type RNA - Muller glia cells [nTPM]":"46.4","Single Cell Type RNA - NK-cells [nTPM]":"70.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"53.0","Single Cell Type RNA - Paneth cells [nTPM]":"47.0","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"60.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"48.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.0","Single Cell Type RNA - Spermatocytes [nTPM]":"33.7","Single Cell Type RNA - Spermatogonia [nTPM]":"34.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"371.0","Single Cell Type RNA - T-cells [nTPM]":"38.0","Single Cell Type RNA - Theca cells [nTPM]":"57.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.7","Single Cell Type RNA - Urothelial cells [nTPM]":"32.3"},{"Gene":"EIF2AK2","Gene synonym":["EIF2AK1","PKR","PPP1R83","PRKR"],"Ensembl":"ENSG00000055332","Gene description":"Eukaryotic translation initiation factor 2 alpha kinase 2","Uniprot":["P19525"],"Chromosome":"2","Position":"37099210-37157522","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["Kinase","RNA-binding","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003845","HPA019795","HPA063893"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB003845":"AB_562332","HPA019795":"AB_1848060","HPA063893":"AB_2685144"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.77e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.1","Tissue RNA - adrenal gland [nTPM]":"9.0","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"10.5","Tissue RNA - basal ganglia [nTPM]":"8.1","Tissue RNA - bone marrow [nTPM]":"30.1","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"7.4","Tissue RNA - cerebral cortex [nTPM]":"9.5","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"8.3","Tissue RNA - gallbladder [nTPM]":"9.5","Tissue RNA - heart muscle [nTPM]":"6.3","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"11.1","Tissue RNA - kidney [nTPM]":"8.5","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"8.9","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"10.9","Tissue RNA - midbrain [nTPM]":"8.1","Tissue RNA - ovary [nTPM]":"10.8","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"6.6","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"10.9","Tissue RNA - prostate [nTPM]":"10.1","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"17.7","Tissue RNA - seminal vesicle [nTPM]":"8.4","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"9.9","Tissue RNA - smooth muscle [nTPM]":"11.1","Tissue RNA - spinal cord [nTPM]":"15.6","Tissue RNA - spleen [nTPM]":"11.9","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"13.0","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"8.0","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"8.7","Cell RNA - A-431 [nTPM]":"38.4","Cell RNA - A549 [nTPM]":"22.1","Cell RNA - AF22 [nTPM]":"16.7","Cell RNA - AN3-CA [nTPM]":"17.4","Cell RNA - ASC diff [nTPM]":"21.5","Cell RNA - ASC TERT1 [nTPM]":"28.3","Cell RNA - BEWO [nTPM]":"20.1","Cell RNA - BJ [nTPM]":"21.2","Cell RNA - BJ hTERT+ [nTPM]":"29.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"56.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.1","Cell RNA - CACO-2 [nTPM]":"23.0","Cell RNA - CAPAN-2 [nTPM]":"23.2","Cell RNA - Daudi [nTPM]":"27.4","Cell RNA - EFO-21 [nTPM]":"27.0","Cell RNA - fHDF\/TERT166 [nTPM]":"29.8","Cell RNA - GAMG [nTPM]":"66.2","Cell RNA - HaCaT [nTPM]":"27.4","Cell RNA - HAP1 [nTPM]":"24.2","Cell RNA - HBEC3-KT [nTPM]":"27.1","Cell RNA - HBF TERT88 [nTPM]":"29.5","Cell RNA - HDLM-2 [nTPM]":"45.7","Cell RNA - HEK 293 [nTPM]":"12.0","Cell RNA - HEL [nTPM]":"33.8","Cell RNA - HeLa [nTPM]":"19.2","Cell RNA - Hep G2 [nTPM]":"18.7","Cell RNA - HHSteC [nTPM]":"17.9","Cell RNA - HL-60 [nTPM]":"32.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"22.5","Cell RNA - hTCEpi [nTPM]":"13.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.7","Cell RNA - hTERT-HME1 [nTPM]":"19.3","Cell RNA - hTERT-RPE1 [nTPM]":"17.7","Cell RNA - HUVEC TERT2 [nTPM]":"18.0","Cell RNA - JURKAT [nTPM]":"10.7","Cell RNA - K-562 [nTPM]":"19.1","Cell RNA - Karpas-707 [nTPM]":"23.6","Cell RNA - LHCN-M2 [nTPM]":"20.3","Cell RNA - MCF7 [nTPM]":"13.4","Cell RNA - MOLT-4 [nTPM]":"35.5","Cell RNA - NB-4 [nTPM]":"17.0","Cell RNA - NTERA-2 [nTPM]":"15.8","Cell RNA - OE19 [nTPM]":"8.4","Cell RNA - PC-3 [nTPM]":"10.8","Cell RNA - REH [nTPM]":"27.6","Cell RNA - RH-30 [nTPM]":"40.9","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"18.7","Cell RNA - SCLC-21H [nTPM]":"14.1","Cell RNA - SH-SY5Y [nTPM]":"20.4","Cell RNA - SiHa [nTPM]":"32.0","Cell RNA - SK-BR-3 [nTPM]":"24.0","Cell RNA - SK-MEL-30 [nTPM]":"50.7","Cell RNA - SuSa [nTPM]":"12.7","Cell RNA - T-47d [nTPM]":"9.2","Cell RNA - THP-1 [nTPM]":"9.0","Cell RNA - TIME [nTPM]":"31.4","Cell RNA - U-138 MG [nTPM]":"25.7","Cell RNA - U-2 OS [nTPM]":"24.9","Cell RNA - U-2197 [nTPM]":"15.1","Cell RNA - U-251 MG [nTPM]":"36.2","Cell RNA - U-266\/70 [nTPM]":"19.0","Cell RNA - U-266\/84 [nTPM]":"30.8","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"15.9","Cell RNA - U-937 [nTPM]":"20.0","Cell RNA - WM-115 [nTPM]":"23.1","Blood RNA - basophil [nTPM]":"10.7","Blood RNA - classical monocyte [nTPM]":"5.3","Blood RNA - eosinophil [nTPM]":"6.3","Blood RNA - gdT-cell [nTPM]":"5.4","Blood RNA - intermediate monocyte [nTPM]":"7.9","Blood RNA - MAIT T-cell [nTPM]":"5.2","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.2","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"4.2","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"15.7","Blood RNA - NK-cell [nTPM]":"6.5","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"6.5","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"8.1","Brain RNA - cerebellum [nTPM]":"7.4","Brain RNA - cerebral cortex [nTPM]":"9.5","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"11.1","Brain RNA - medulla oblongata [nTPM]":"10.9","Brain RNA - midbrain [nTPM]":"8.1","Brain RNA - pons [nTPM]":"10.9","Brain RNA - spinal cord [nTPM]":"15.6","Brain RNA - thalamus [nTPM]":"13.0","Brain RNA - white matter [nTPM]":"8.7","Single Cell Type RNA - Adipocytes [nTPM]":"94.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.0","Single Cell Type RNA - Astrocytes [nTPM]":"25.1","Single Cell Type RNA - B-cells [nTPM]":"35.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"38.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"46.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.8","Single Cell Type RNA - dendritic cells [nTPM]":"44.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"40.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"55.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"68.7","Single Cell Type RNA - Endothelial cells [nTPM]":"76.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"36.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"48.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"89.2","Single Cell Type RNA - Fibroblasts [nTPM]":"52.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.7","Single Cell Type RNA - granulocytes [nTPM]":"41.1","Single Cell Type RNA - Granulosa cells [nTPM]":"93.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.5","Single Cell Type RNA - Hepatocytes [nTPM]":"21.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.2","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"29.9","Single Cell Type RNA - Langerhans cells [nTPM]":"20.8","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"57.2","Single Cell Type RNA - Macrophages [nTPM]":"50.7","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"48.7","Single Cell Type RNA - monocytes [nTPM]":"47.1","Single Cell Type RNA - Muller glia cells [nTPM]":"50.9","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"51.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.7","Single Cell Type RNA - Paneth cells [nTPM]":"21.8","Single Cell Type RNA - Peritubular cells [nTPM]":"84.2","Single Cell Type RNA - Plasma cells [nTPM]":"46.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"48.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.8","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"40.8","Single Cell Type RNA - T-cells [nTPM]":"40.0","Single Cell Type RNA - Theca cells [nTPM]":"61.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.6","Single Cell Type RNA - Urothelial cells [nTPM]":"40.5"},{"Gene":"EIF2B1","Gene synonym":["EIF-2B","EIF-2Balpha","EIF2B","EIF2BA"],"Ensembl":"ENSG00000111361","Gene description":"Eukaryotic translation initiation factor 2B subunit alpha","Uniprot":["Q14232"],"Chromosome":"12","Position":"123620406-123633766","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Initiation factor"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034258","HPA049509"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034258":"AB_2095995","HPA049509":"AB_2680797"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.75e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.9","Tissue RNA - adrenal gland [nTPM]":"32.1","Tissue RNA - amygdala [nTPM]":"23.5","Tissue RNA - appendix [nTPM]":"33.0","Tissue RNA - basal ganglia [nTPM]":"25.7","Tissue RNA - bone marrow [nTPM]":"36.4","Tissue RNA - breast [nTPM]":"31.5","Tissue RNA - cerebellum [nTPM]":"27.8","Tissue RNA - cerebral cortex [nTPM]":"27.9","Tissue RNA - cervix [nTPM]":"33.1","Tissue RNA - choroid plexus [nTPM]":"23.9","Tissue RNA - colon [nTPM]":"33.2","Tissue RNA - duodenum [nTPM]":"27.6","Tissue RNA - endometrium 1 [nTPM]":"34.0","Tissue RNA - epididymis [nTPM]":"29.5","Tissue RNA - esophagus [nTPM]":"33.8","Tissue RNA - fallopian tube [nTPM]":"31.1","Tissue RNA - gallbladder [nTPM]":"22.0","Tissue RNA - heart muscle [nTPM]":"26.3","Tissue RNA - hippocampal formation [nTPM]":"24.8","Tissue RNA - hypothalamus [nTPM]":"23.7","Tissue RNA - kidney [nTPM]":"28.7","Tissue RNA - liver [nTPM]":"29.0","Tissue RNA - lung [nTPM]":"24.4","Tissue RNA - lymph node [nTPM]":"40.4","Tissue RNA - medulla oblongata [nTPM]":"25.4","Tissue RNA - midbrain [nTPM]":"23.8","Tissue RNA - ovary [nTPM]":"34.1","Tissue RNA - pancreas [nTPM]":"32.9","Tissue RNA - parathyroid gland [nTPM]":"21.7","Tissue RNA - pituitary gland [nTPM]":"28.2","Tissue RNA - placenta [nTPM]":"31.0","Tissue RNA - pons [nTPM]":"27.4","Tissue RNA - prostate [nTPM]":"29.4","Tissue RNA - rectum [nTPM]":"30.8","Tissue RNA - retina [nTPM]":"23.5","Tissue RNA - salivary gland [nTPM]":"28.8","Tissue RNA - seminal vesicle [nTPM]":"26.2","Tissue RNA - skeletal muscle [nTPM]":"43.1","Tissue RNA - skin 1 [nTPM]":"51.1","Tissue RNA - small intestine [nTPM]":"29.2","Tissue RNA - smooth muscle [nTPM]":"31.5","Tissue RNA - spinal cord [nTPM]":"23.9","Tissue RNA - spleen [nTPM]":"33.4","Tissue RNA - stomach 1 [nTPM]":"28.7","Tissue RNA - testis [nTPM]":"22.6","Tissue RNA - thalamus [nTPM]":"25.7","Tissue RNA - thymus [nTPM]":"30.0","Tissue RNA - thyroid gland [nTPM]":"27.4","Tissue RNA - tongue [nTPM]":"27.3","Tissue RNA - tonsil [nTPM]":"43.1","Tissue RNA - urinary bladder [nTPM]":"32.5","Tissue RNA - vagina [nTPM]":"31.2","Tissue RNA - white matter [nTPM]":"32.2","Cell RNA - A-431 [nTPM]":"55.6","Cell RNA - A549 [nTPM]":"47.9","Cell RNA - AF22 [nTPM]":"50.0","Cell RNA - AN3-CA [nTPM]":"53.1","Cell RNA - ASC diff [nTPM]":"45.8","Cell RNA - ASC TERT1 [nTPM]":"46.2","Cell RNA - BEWO [nTPM]":"52.5","Cell RNA - BJ [nTPM]":"66.8","Cell RNA - BJ hTERT+ [nTPM]":"38.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"46.7","Cell RNA - CACO-2 [nTPM]":"62.8","Cell RNA - CAPAN-2 [nTPM]":"34.0","Cell RNA - Daudi [nTPM]":"104.2","Cell RNA - EFO-21 [nTPM]":"77.3","Cell RNA - fHDF\/TERT166 [nTPM]":"51.1","Cell RNA - GAMG [nTPM]":"28.6","Cell RNA - HaCaT [nTPM]":"54.3","Cell RNA - HAP1 [nTPM]":"79.0","Cell RNA - HBEC3-KT [nTPM]":"52.0","Cell RNA - HBF TERT88 [nTPM]":"67.3","Cell RNA - HDLM-2 [nTPM]":"85.4","Cell RNA - HEK 293 [nTPM]":"87.8","Cell RNA - HEL [nTPM]":"74.9","Cell RNA - HeLa [nTPM]":"68.3","Cell RNA - Hep G2 [nTPM]":"55.6","Cell RNA - HHSteC [nTPM]":"43.3","Cell RNA - HL-60 [nTPM]":"106.9","Cell RNA - HMC-1 [nTPM]":"90.2","Cell RNA - HSkMC [nTPM]":"42.0","Cell RNA - hTCEpi [nTPM]":"63.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.4","Cell RNA - hTERT-HME1 [nTPM]":"38.9","Cell RNA - hTERT-RPE1 [nTPM]":"54.0","Cell RNA - HUVEC TERT2 [nTPM]":"59.6","Cell RNA - JURKAT [nTPM]":"66.8","Cell RNA - K-562 [nTPM]":"136.4","Cell RNA - Karpas-707 [nTPM]":"34.2","Cell RNA - LHCN-M2 [nTPM]":"60.2","Cell RNA - MCF7 [nTPM]":"50.4","Cell RNA - MOLT-4 [nTPM]":"86.1","Cell RNA - NB-4 [nTPM]":"113.3","Cell RNA - NTERA-2 [nTPM]":"82.4","Cell RNA - OE19 [nTPM]":"59.5","Cell RNA - PC-3 [nTPM]":"64.1","Cell RNA - REH [nTPM]":"89.5","Cell RNA - RH-30 [nTPM]":"61.1","Cell RNA - RPMI-8226 [nTPM]":"79.2","Cell RNA - RPTEC TERT1 [nTPM]":"43.2","Cell RNA - RT4 [nTPM]":"46.0","Cell RNA - SCLC-21H [nTPM]":"61.9","Cell RNA - SH-SY5Y [nTPM]":"69.9","Cell RNA - SiHa [nTPM]":"49.4","Cell RNA - SK-BR-3 [nTPM]":"48.7","Cell RNA - SK-MEL-30 [nTPM]":"63.3","Cell RNA - SuSa [nTPM]":"46.7","Cell RNA - T-47d [nTPM]":"88.5","Cell RNA - THP-1 [nTPM]":"63.2","Cell RNA - TIME [nTPM]":"56.8","Cell RNA - U-138 MG [nTPM]":"43.8","Cell RNA - U-2 OS [nTPM]":"52.9","Cell RNA - U-2197 [nTPM]":"63.2","Cell RNA - U-251 MG [nTPM]":"62.4","Cell RNA - U-266\/70 [nTPM]":"90.9","Cell RNA - U-266\/84 [nTPM]":"102.1","Cell RNA - U-698 [nTPM]":"153.6","Cell RNA - U-87 MG [nTPM]":"63.6","Cell RNA - U-937 [nTPM]":"71.7","Cell RNA - WM-115 [nTPM]":"63.9","Blood RNA - basophil [nTPM]":"113.2","Blood RNA - classical monocyte [nTPM]":"87.3","Blood RNA - eosinophil [nTPM]":"119.3","Blood RNA - gdT-cell [nTPM]":"56.3","Blood RNA - intermediate monocyte [nTPM]":"104.2","Blood RNA - MAIT T-cell [nTPM]":"51.3","Blood RNA - memory B-cell [nTPM]":"60.1","Blood RNA - memory CD4 T-cell [nTPM]":"57.2","Blood RNA - memory CD8 T-cell [nTPM]":"58.9","Blood RNA - myeloid DC [nTPM]":"95.7","Blood RNA - naive B-cell [nTPM]":"53.2","Blood RNA - naive CD4 T-cell [nTPM]":"58.0","Blood RNA - naive CD8 T-cell [nTPM]":"53.9","Blood RNA - neutrophil [nTPM]":"9.8","Blood RNA - NK-cell [nTPM]":"64.8","Blood RNA - non-classical monocyte [nTPM]":"101.6","Blood RNA - plasmacytoid DC [nTPM]":"59.9","Blood RNA - T-reg [nTPM]":"73.2","Blood RNA - total PBMC [nTPM]":"100.7","Brain RNA - amygdala [nTPM]":"23.5","Brain RNA - basal ganglia [nTPM]":"25.7","Brain RNA - cerebellum [nTPM]":"27.8","Brain RNA - cerebral cortex [nTPM]":"27.9","Brain RNA - hippocampal formation [nTPM]":"24.8","Brain RNA - hypothalamus [nTPM]":"23.7","Brain RNA - medulla oblongata [nTPM]":"25.4","Brain RNA - midbrain [nTPM]":"23.8","Brain RNA - pons [nTPM]":"27.4","Brain RNA - spinal cord [nTPM]":"23.9","Brain RNA - thalamus [nTPM]":"25.7","Brain RNA - white matter [nTPM]":"32.2","Single Cell Type RNA - Adipocytes [nTPM]":"29.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.6","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"29.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"19.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"19.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"69.0","Single Cell Type RNA - dendritic cells [nTPM]":"33.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"33.0","Single Cell Type RNA - Early spermatids [nTPM]":"7.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.3","Single Cell Type RNA - Endothelial cells [nTPM]":"26.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"21.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"40.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.8","Single Cell Type RNA - Fibroblasts [nTPM]":"23.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.2","Single Cell Type RNA - granulocytes [nTPM]":"41.2","Single Cell Type RNA - Granulosa cells [nTPM]":"24.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"13.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.8","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.4","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"18.6","Single Cell Type RNA - Langerhans cells [nTPM]":"18.5","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"25.1","Single Cell Type RNA - Macrophages [nTPM]":"26.0","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"30.6","Single Cell Type RNA - Muller glia cells [nTPM]":"34.4","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.8","Single Cell Type RNA - Paneth cells [nTPM]":"23.8","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"30.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.6","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.8","Single Cell Type RNA - Spermatocytes [nTPM]":"49.2","Single Cell Type RNA - Spermatogonia [nTPM]":"38.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"51.6","Single Cell Type RNA - T-cells [nTPM]":"26.7","Single Cell Type RNA - Theca cells [nTPM]":"29.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"14.6"},{"Gene":"EIF2B2","Gene synonym":["EIF-2Bbeta","EIF2B"],"Ensembl":"ENSG00000119718","Gene description":"Eukaryotic translation initiation factor 2B subunit beta","Uniprot":["P49770"],"Chromosome":"14","Position":"75002921-75012366","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Initiation factor"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"165.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005841","CAB037105","HPA048028"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Plasma membrane","Focal adhesion sites"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB037105":"AB_1840834","HPA005841":"AB_1078725","HPA048028":"AB_2680235"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.95e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.7","Tissue RNA - adrenal gland [nTPM]":"5.3","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"4.5","Tissue RNA - bone marrow [nTPM]":"3.2","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"8.7","Tissue RNA - cerebral cortex [nTPM]":"4.8","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"3.0","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"3.1","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"4.9","Tissue RNA - liver [nTPM]":"3.3","Tissue RNA - lung [nTPM]":"2.7","Tissue RNA - lymph node [nTPM]":"4.0","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"8.5","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"3.8","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"2.8","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"4.0","Tissue RNA - small intestine [nTPM]":"2.8","Tissue RNA - smooth muscle [nTPM]":"3.4","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"2.7","Tissue RNA - stomach 1 [nTPM]":"2.6","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"11.5","Tissue RNA - tongue [nTPM]":"7.1","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"6.9","Cell RNA - A-431 [nTPM]":"5.9","Cell RNA - A549 [nTPM]":"7.0","Cell RNA - AF22 [nTPM]":"5.6","Cell RNA - AN3-CA [nTPM]":"6.4","Cell RNA - ASC diff [nTPM]":"6.3","Cell RNA - ASC TERT1 [nTPM]":"5.2","Cell RNA - BEWO [nTPM]":"7.4","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.2","Cell RNA - CACO-2 [nTPM]":"9.0","Cell RNA - CAPAN-2 [nTPM]":"5.9","Cell RNA - Daudi [nTPM]":"5.2","Cell RNA - EFO-21 [nTPM]":"2.3","Cell RNA - fHDF\/TERT166 [nTPM]":"5.8","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"8.8","Cell RNA - HBEC3-KT [nTPM]":"8.7","Cell RNA - HBF TERT88 [nTPM]":"10.6","Cell RNA - HDLM-2 [nTPM]":"3.2","Cell RNA - HEK 293 [nTPM]":"6.5","Cell RNA - HEL [nTPM]":"4.6","Cell RNA - HeLa [nTPM]":"6.3","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"8.2","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"4.8","Cell RNA - hTCEpi [nTPM]":"8.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.1","Cell RNA - hTERT-HME1 [nTPM]":"9.3","Cell RNA - hTERT-RPE1 [nTPM]":"6.1","Cell RNA - HUVEC TERT2 [nTPM]":"24.8","Cell RNA - JURKAT [nTPM]":"4.5","Cell RNA - K-562 [nTPM]":"4.2","Cell RNA - Karpas-707 [nTPM]":"4.9","Cell RNA - LHCN-M2 [nTPM]":"15.5","Cell RNA - MCF7 [nTPM]":"17.4","Cell RNA - MOLT-4 [nTPM]":"5.5","Cell RNA - NB-4 [nTPM]":"4.3","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"7.3","Cell RNA - PC-3 [nTPM]":"10.3","Cell RNA - REH [nTPM]":"3.4","Cell RNA - RH-30 [nTPM]":"6.6","Cell RNA - RPMI-8226 [nTPM]":"4.3","Cell RNA - RPTEC TERT1 [nTPM]":"10.1","Cell RNA - RT4 [nTPM]":"7.0","Cell RNA - SCLC-21H [nTPM]":"6.0","Cell RNA - SH-SY5Y [nTPM]":"4.8","Cell RNA - SiHa [nTPM]":"3.9","Cell RNA - SK-BR-3 [nTPM]":"5.5","Cell RNA - SK-MEL-30 [nTPM]":"8.4","Cell RNA - SuSa [nTPM]":"6.9","Cell RNA - T-47d [nTPM]":"9.0","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"6.4","Cell RNA - U-138 MG [nTPM]":"5.4","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"2.4","Cell RNA - U-251 MG [nTPM]":"4.8","Cell RNA - U-266\/70 [nTPM]":"8.4","Cell RNA - U-266\/84 [nTPM]":"7.5","Cell RNA - U-698 [nTPM]":"6.2","Cell RNA - U-87 MG [nTPM]":"5.9","Cell RNA - U-937 [nTPM]":"4.3","Cell RNA - WM-115 [nTPM]":"4.2","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"4.0","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"4.5","Brain RNA - cerebellum [nTPM]":"8.7","Brain RNA - cerebral cortex [nTPM]":"4.8","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"6.9","Single Cell Type RNA - Adipocytes [nTPM]":"18.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"14.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"28.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"21.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"51.5","Single Cell Type RNA - dendritic cells [nTPM]":"16.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"36.2","Single Cell Type RNA - Early spermatids [nTPM]":"12.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.5","Single Cell Type RNA - Endothelial cells [nTPM]":"32.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.6","Single Cell Type RNA - Erythroid cells [nTPM]":"20.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"56.5","Single Cell Type RNA - Fibroblasts [nTPM]":"18.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"17.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"11.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.7","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.0","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"19.1","Single Cell Type RNA - Langerhans cells [nTPM]":"11.9","Single Cell Type RNA - Late spermatids [nTPM]":"12.7","Single Cell Type RNA - Leydig cells [nTPM]":"15.8","Single Cell Type RNA - Macrophages [nTPM]":"18.8","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"28.0","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.1","Single Cell Type RNA - Paneth cells [nTPM]":"11.7","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"11.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"50.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.9","Single Cell Type RNA - Spermatocytes [nTPM]":"84.2","Single Cell Type RNA - Spermatogonia [nTPM]":"27.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"165.5","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"30.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.7","Single Cell Type RNA - Urothelial cells [nTPM]":"19.2"},{"Gene":"EIF2B3","Gene synonym":["EIF-2B","EIF2Bgamma"],"Ensembl":"ENSG00000070785","Gene description":"Eukaryotic translation initiation factor 2B subunit gamma","Uniprot":["Q9NR50"],"Chromosome":"1","Position":"44850522-44986722","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Initiation factor"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024213","HPA024218","HPA024219"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA024213":"AB_1848067","HPA024218":"AB_1848068","HPA024219":"AB_1848069"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.6","Tissue RNA - adrenal gland [nTPM]":"27.2","Tissue RNA - amygdala [nTPM]":"11.4","Tissue RNA - appendix [nTPM]":"11.6","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"10.9","Tissue RNA - breast [nTPM]":"21.9","Tissue RNA - cerebellum [nTPM]":"13.2","Tissue RNA - cerebral cortex [nTPM]":"15.6","Tissue RNA - cervix [nTPM]":"18.7","Tissue RNA - choroid plexus [nTPM]":"10.1","Tissue RNA - colon [nTPM]":"17.5","Tissue RNA - duodenum [nTPM]":"8.6","Tissue RNA - endometrium 1 [nTPM]":"17.0","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"17.4","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"40.6","Tissue RNA - hippocampal formation [nTPM]":"11.2","Tissue RNA - hypothalamus [nTPM]":"11.6","Tissue RNA - kidney [nTPM]":"15.4","Tissue RNA - liver [nTPM]":"24.7","Tissue RNA - lung [nTPM]":"13.5","Tissue RNA - lymph node [nTPM]":"14.3","Tissue RNA - medulla oblongata [nTPM]":"11.9","Tissue RNA - midbrain [nTPM]":"12.1","Tissue RNA - ovary [nTPM]":"18.2","Tissue RNA - pancreas [nTPM]":"16.9","Tissue RNA - parathyroid gland [nTPM]":"30.0","Tissue RNA - pituitary gland [nTPM]":"15.8","Tissue RNA - placenta [nTPM]":"9.7","Tissue RNA - pons [nTPM]":"12.8","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"13.4","Tissue RNA - retina [nTPM]":"19.0","Tissue RNA - salivary gland [nTPM]":"25.1","Tissue RNA - seminal vesicle [nTPM]":"13.7","Tissue RNA - skeletal muscle [nTPM]":"77.0","Tissue RNA - skin 1 [nTPM]":"17.6","Tissue RNA - small intestine [nTPM]":"10.7","Tissue RNA - smooth muscle [nTPM]":"19.4","Tissue RNA - spinal cord [nTPM]":"11.0","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"14.2","Tissue RNA - testis [nTPM]":"19.3","Tissue RNA - thalamus [nTPM]":"11.2","Tissue RNA - thymus [nTPM]":"13.3","Tissue RNA - thyroid gland [nTPM]":"12.5","Tissue RNA - tongue [nTPM]":"48.0","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"17.7","Tissue RNA - vagina [nTPM]":"17.1","Tissue RNA - white matter [nTPM]":"14.0","Cell RNA - A-431 [nTPM]":"35.4","Cell RNA - A549 [nTPM]":"26.9","Cell RNA - AF22 [nTPM]":"30.9","Cell RNA - AN3-CA [nTPM]":"25.5","Cell RNA - ASC diff [nTPM]":"36.3","Cell RNA - ASC TERT1 [nTPM]":"43.1","Cell RNA - BEWO [nTPM]":"36.2","Cell RNA - BJ [nTPM]":"56.1","Cell RNA - BJ hTERT+ [nTPM]":"42.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"56.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.9","Cell RNA - CACO-2 [nTPM]":"39.0","Cell RNA - CAPAN-2 [nTPM]":"20.7","Cell RNA - Daudi [nTPM]":"90.6","Cell RNA - EFO-21 [nTPM]":"39.9","Cell RNA - fHDF\/TERT166 [nTPM]":"43.2","Cell RNA - GAMG [nTPM]":"45.0","Cell RNA - HaCaT [nTPM]":"20.6","Cell RNA - HAP1 [nTPM]":"65.3","Cell RNA - HBEC3-KT [nTPM]":"48.6","Cell RNA - HBF TERT88 [nTPM]":"69.5","Cell RNA - HDLM-2 [nTPM]":"32.5","Cell RNA - HEK 293 [nTPM]":"58.1","Cell RNA - HEL [nTPM]":"44.3","Cell RNA - HeLa [nTPM]":"29.3","Cell RNA - Hep G2 [nTPM]":"38.4","Cell RNA - HHSteC [nTPM]":"46.2","Cell RNA - HL-60 [nTPM]":"71.2","Cell RNA - HMC-1 [nTPM]":"24.3","Cell RNA - HSkMC [nTPM]":"29.3","Cell RNA - hTCEpi [nTPM]":"25.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"61.0","Cell RNA - hTERT-HME1 [nTPM]":"69.9","Cell RNA - hTERT-RPE1 [nTPM]":"26.5","Cell RNA - HUVEC TERT2 [nTPM]":"52.8","Cell RNA - JURKAT [nTPM]":"30.1","Cell RNA - K-562 [nTPM]":"106.1","Cell RNA - Karpas-707 [nTPM]":"31.6","Cell RNA - LHCN-M2 [nTPM]":"62.3","Cell RNA - MCF7 [nTPM]":"23.1","Cell RNA - MOLT-4 [nTPM]":"69.7","Cell RNA - NB-4 [nTPM]":"30.2","Cell RNA - NTERA-2 [nTPM]":"42.0","Cell RNA - OE19 [nTPM]":"38.8","Cell RNA - PC-3 [nTPM]":"52.7","Cell RNA - REH [nTPM]":"54.7","Cell RNA - RH-30 [nTPM]":"51.3","Cell RNA - RPMI-8226 [nTPM]":"65.7","Cell RNA - RPTEC TERT1 [nTPM]":"28.7","Cell RNA - RT4 [nTPM]":"15.7","Cell RNA - SCLC-21H [nTPM]":"53.2","Cell RNA - SH-SY5Y [nTPM]":"20.5","Cell RNA - SiHa [nTPM]":"55.1","Cell RNA - SK-BR-3 [nTPM]":"63.8","Cell RNA - SK-MEL-30 [nTPM]":"37.4","Cell RNA - SuSa [nTPM]":"40.7","Cell RNA - T-47d [nTPM]":"24.7","Cell RNA - THP-1 [nTPM]":"32.8","Cell RNA - TIME [nTPM]":"28.3","Cell RNA - U-138 MG [nTPM]":"35.9","Cell RNA - U-2 OS [nTPM]":"42.9","Cell RNA - U-2197 [nTPM]":"53.4","Cell RNA - U-251 MG [nTPM]":"73.7","Cell RNA - U-266\/70 [nTPM]":"31.6","Cell RNA - U-266\/84 [nTPM]":"37.9","Cell RNA - U-698 [nTPM]":"68.9","Cell RNA - U-87 MG [nTPM]":"27.9","Cell RNA - U-937 [nTPM]":"59.5","Cell RNA - WM-115 [nTPM]":"43.1","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"23.4","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"18.6","Blood RNA - intermediate monocyte [nTPM]":"37.2","Blood RNA - MAIT T-cell [nTPM]":"22.8","Blood RNA - memory B-cell [nTPM]":"14.8","Blood RNA - memory CD4 T-cell [nTPM]":"18.3","Blood RNA - memory CD8 T-cell [nTPM]":"21.1","Blood RNA - myeloid DC [nTPM]":"37.0","Blood RNA - naive B-cell [nTPM]":"18.9","Blood RNA - naive CD4 T-cell [nTPM]":"22.9","Blood RNA - naive CD8 T-cell [nTPM]":"23.6","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"25.5","Blood RNA - non-classical monocyte [nTPM]":"33.1","Blood RNA - plasmacytoid DC [nTPM]":"25.3","Blood RNA - T-reg [nTPM]":"17.6","Blood RNA - total PBMC [nTPM]":"21.4","Brain RNA - amygdala [nTPM]":"11.4","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"13.2","Brain RNA - cerebral cortex [nTPM]":"15.6","Brain RNA - hippocampal formation [nTPM]":"11.2","Brain RNA - hypothalamus [nTPM]":"11.6","Brain RNA - medulla oblongata [nTPM]":"11.9","Brain RNA - midbrain [nTPM]":"12.1","Brain RNA - pons [nTPM]":"12.8","Brain RNA - spinal cord [nTPM]":"11.0","Brain RNA - thalamus [nTPM]":"11.2","Brain RNA - white matter [nTPM]":"14.0","Single Cell Type RNA - Adipocytes [nTPM]":"13.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.0","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"15.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"15.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"79.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"24.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.1","Single Cell Type RNA - dendritic cells [nTPM]":"12.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"18.9","Single Cell Type RNA - Early spermatids [nTPM]":"26.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.0","Single Cell Type RNA - Endothelial cells [nTPM]":"14.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"15.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.6","Single Cell Type RNA - Fibroblasts [nTPM]":"22.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.5","Single Cell Type RNA - granulocytes [nTPM]":"25.9","Single Cell Type RNA - Granulosa cells [nTPM]":"21.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"22.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.8","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"44.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.0","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"10.7","Single Cell Type RNA - Langerhans cells [nTPM]":"11.2","Single Cell Type RNA - Late spermatids [nTPM]":"11.3","Single Cell Type RNA - Leydig cells [nTPM]":"26.4","Single Cell Type RNA - Macrophages [nTPM]":"15.4","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"30.1","Single Cell Type RNA - Muller glia cells [nTPM]":"21.7","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"29.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.7","Single Cell Type RNA - Paneth cells [nTPM]":"6.9","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"22.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.4","Single Cell Type RNA - Spermatocytes [nTPM]":"45.5","Single Cell Type RNA - Spermatogonia [nTPM]":"23.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.9","Single Cell Type RNA - T-cells [nTPM]":"13.5","Single Cell Type RNA - Theca cells [nTPM]":"40.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.4","Single Cell Type RNA - Urothelial cells [nTPM]":"13.9"},{"Gene":"EIF2B4","Gene synonym":["DKFZP586J0119","EIF-2B","EIF2B","EIF2Bdelta"],"Ensembl":"ENSG00000115211","Gene description":"Eukaryotic translation initiation factor 2B subunit delta","Uniprot":["Q9UI10"],"Chromosome":"2","Position":"27364352-27370457","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Initiation factor"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"196.4","Late spermatids":"299.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032234","HPA039993","HPA068855"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB032234":"AB_668909","HPA039993":"AB_2676790","HPA068855":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.4","Tissue RNA - adrenal gland [nTPM]":"24.8","Tissue RNA - amygdala [nTPM]":"23.3","Tissue RNA - appendix [nTPM]":"15.2","Tissue RNA - basal ganglia [nTPM]":"24.3","Tissue RNA - bone marrow [nTPM]":"10.7","Tissue RNA - breast [nTPM]":"20.7","Tissue RNA - cerebellum [nTPM]":"24.0","Tissue RNA - cerebral cortex [nTPM]":"23.8","Tissue RNA - cervix [nTPM]":"21.3","Tissue RNA - choroid plexus [nTPM]":"22.5","Tissue RNA - colon [nTPM]":"31.7","Tissue RNA - duodenum [nTPM]":"14.6","Tissue RNA - endometrium 1 [nTPM]":"21.0","Tissue RNA - epididymis [nTPM]":"16.9","Tissue RNA - esophagus [nTPM]":"27.8","Tissue RNA - fallopian tube [nTPM]":"20.3","Tissue RNA - gallbladder [nTPM]":"13.4","Tissue RNA - heart muscle [nTPM]":"28.0","Tissue RNA - hippocampal formation [nTPM]":"23.2","Tissue RNA - hypothalamus [nTPM]":"23.7","Tissue RNA - kidney [nTPM]":"18.2","Tissue RNA - liver [nTPM]":"21.5","Tissue RNA - lung [nTPM]":"18.1","Tissue RNA - lymph node [nTPM]":"17.2","Tissue RNA - medulla oblongata [nTPM]":"24.4","Tissue RNA - midbrain [nTPM]":"24.3","Tissue RNA - ovary [nTPM]":"19.8","Tissue RNA - pancreas [nTPM]":"31.4","Tissue RNA - parathyroid gland [nTPM]":"20.4","Tissue RNA - pituitary gland [nTPM]":"20.3","Tissue RNA - placenta [nTPM]":"18.8","Tissue RNA - pons [nTPM]":"24.0","Tissue RNA - prostate [nTPM]":"25.4","Tissue RNA - rectum [nTPM]":"18.4","Tissue RNA - retina [nTPM]":"19.3","Tissue RNA - salivary gland [nTPM]":"24.6","Tissue RNA - seminal vesicle [nTPM]":"20.8","Tissue RNA - skeletal muscle [nTPM]":"51.8","Tissue RNA - skin 1 [nTPM]":"29.3","Tissue RNA - small intestine [nTPM]":"18.4","Tissue RNA - smooth muscle [nTPM]":"22.8","Tissue RNA - spinal cord [nTPM]":"23.2","Tissue RNA - spleen [nTPM]":"18.6","Tissue RNA - stomach 1 [nTPM]":"24.7","Tissue RNA - testis [nTPM]":"38.1","Tissue RNA - thalamus [nTPM]":"24.4","Tissue RNA - thymus [nTPM]":"18.9","Tissue RNA - thyroid gland [nTPM]":"18.1","Tissue RNA - tongue [nTPM]":"35.2","Tissue RNA - tonsil [nTPM]":"22.9","Tissue RNA - urinary bladder [nTPM]":"24.1","Tissue RNA - vagina [nTPM]":"21.4","Tissue RNA - white matter [nTPM]":"24.1","Cell RNA - A-431 [nTPM]":"38.7","Cell RNA - A549 [nTPM]":"59.8","Cell RNA - AF22 [nTPM]":"44.3","Cell RNA - AN3-CA [nTPM]":"34.6","Cell RNA - ASC diff [nTPM]":"58.4","Cell RNA - ASC TERT1 [nTPM]":"42.7","Cell RNA - BEWO [nTPM]":"48.4","Cell RNA - BJ [nTPM]":"41.0","Cell RNA - BJ hTERT+ [nTPM]":"43.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"55.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.3","Cell RNA - CACO-2 [nTPM]":"89.2","Cell RNA - CAPAN-2 [nTPM]":"16.9","Cell RNA - Daudi [nTPM]":"49.7","Cell RNA - EFO-21 [nTPM]":"38.7","Cell RNA - fHDF\/TERT166 [nTPM]":"48.7","Cell RNA - GAMG [nTPM]":"46.6","Cell RNA - HaCaT [nTPM]":"27.6","Cell RNA - HAP1 [nTPM]":"62.5","Cell RNA - HBEC3-KT [nTPM]":"50.8","Cell RNA - HBF TERT88 [nTPM]":"36.2","Cell RNA - HDLM-2 [nTPM]":"37.4","Cell RNA - HEK 293 [nTPM]":"40.7","Cell RNA - HEL [nTPM]":"61.7","Cell RNA - HeLa [nTPM]":"39.3","Cell RNA - Hep G2 [nTPM]":"104.5","Cell RNA - HHSteC [nTPM]":"51.1","Cell RNA - HL-60 [nTPM]":"58.2","Cell RNA - HMC-1 [nTPM]":"23.0","Cell RNA - HSkMC [nTPM]":"41.3","Cell RNA - hTCEpi [nTPM]":"51.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"69.2","Cell RNA - hTERT-HME1 [nTPM]":"51.6","Cell RNA - hTERT-RPE1 [nTPM]":"40.4","Cell RNA - HUVEC TERT2 [nTPM]":"53.3","Cell RNA - JURKAT [nTPM]":"37.2","Cell RNA - K-562 [nTPM]":"59.5","Cell RNA - Karpas-707 [nTPM]":"24.9","Cell RNA - LHCN-M2 [nTPM]":"53.0","Cell RNA - MCF7 [nTPM]":"35.2","Cell RNA - MOLT-4 [nTPM]":"28.8","Cell RNA - NB-4 [nTPM]":"61.7","Cell RNA - NTERA-2 [nTPM]":"49.1","Cell RNA - OE19 [nTPM]":"59.8","Cell RNA - PC-3 [nTPM]":"38.9","Cell RNA - REH [nTPM]":"52.9","Cell RNA - RH-30 [nTPM]":"69.9","Cell RNA - RPMI-8226 [nTPM]":"43.2","Cell RNA - RPTEC TERT1 [nTPM]":"50.0","Cell RNA - RT4 [nTPM]":"32.7","Cell RNA - SCLC-21H [nTPM]":"34.3","Cell RNA - SH-SY5Y [nTPM]":"37.4","Cell RNA - SiHa [nTPM]":"34.1","Cell RNA - SK-BR-3 [nTPM]":"53.8","Cell RNA - SK-MEL-30 [nTPM]":"42.6","Cell RNA - SuSa [nTPM]":"39.6","Cell RNA - T-47d [nTPM]":"31.3","Cell RNA - THP-1 [nTPM]":"23.4","Cell RNA - TIME [nTPM]":"52.8","Cell RNA - U-138 MG [nTPM]":"40.1","Cell RNA - U-2 OS [nTPM]":"47.0","Cell RNA - U-2197 [nTPM]":"35.4","Cell RNA - U-251 MG [nTPM]":"49.7","Cell RNA - U-266\/70 [nTPM]":"50.9","Cell RNA - U-266\/84 [nTPM]":"65.7","Cell RNA - U-698 [nTPM]":"74.7","Cell RNA - U-87 MG [nTPM]":"33.9","Cell RNA - U-937 [nTPM]":"47.9","Cell RNA - WM-115 [nTPM]":"38.6","Blood RNA - basophil [nTPM]":"56.6","Blood RNA - classical monocyte [nTPM]":"53.9","Blood RNA - eosinophil [nTPM]":"38.8","Blood RNA - gdT-cell [nTPM]":"32.1","Blood RNA - intermediate monocyte [nTPM]":"48.1","Blood RNA - MAIT T-cell [nTPM]":"44.6","Blood RNA - memory B-cell [nTPM]":"31.1","Blood RNA - memory CD4 T-cell [nTPM]":"31.6","Blood RNA - memory CD8 T-cell [nTPM]":"32.6","Blood RNA - myeloid DC [nTPM]":"52.5","Blood RNA - naive B-cell [nTPM]":"25.3","Blood RNA - naive CD4 T-cell [nTPM]":"30.2","Blood RNA - naive CD8 T-cell [nTPM]":"32.9","Blood RNA - neutrophil [nTPM]":"7.7","Blood RNA - NK-cell [nTPM]":"30.8","Blood RNA - non-classical monocyte [nTPM]":"52.2","Blood RNA - plasmacytoid DC [nTPM]":"38.6","Blood RNA - T-reg [nTPM]":"43.8","Blood RNA - total PBMC [nTPM]":"43.2","Brain RNA - amygdala [nTPM]":"23.3","Brain RNA - basal ganglia [nTPM]":"24.3","Brain RNA - cerebellum [nTPM]":"24.0","Brain RNA - cerebral cortex [nTPM]":"23.8","Brain RNA - hippocampal formation [nTPM]":"23.2","Brain RNA - hypothalamus [nTPM]":"23.7","Brain RNA - medulla oblongata [nTPM]":"24.4","Brain RNA - midbrain [nTPM]":"24.3","Brain RNA - pons [nTPM]":"24.0","Brain RNA - spinal cord [nTPM]":"23.2","Brain RNA - thalamus [nTPM]":"24.4","Brain RNA - white matter [nTPM]":"24.1","Single Cell Type RNA - Adipocytes [nTPM]":"19.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"17.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"22.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"27.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.9","Single Cell Type RNA - dendritic cells [nTPM]":"27.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"29.0","Single Cell Type RNA - Early spermatids [nTPM]":"196.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.9","Single Cell Type RNA - Endothelial cells [nTPM]":"19.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.0","Single Cell Type RNA - Fibroblasts [nTPM]":"24.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.6","Single Cell Type RNA - granulocytes [nTPM]":"31.6","Single Cell Type RNA - Granulosa cells [nTPM]":"16.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"34.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.3","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.8","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"20.7","Single Cell Type RNA - Langerhans cells [nTPM]":"28.0","Single Cell Type RNA - Late spermatids [nTPM]":"299.6","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"16.5","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"29.5","Single Cell Type RNA - Muller glia cells [nTPM]":"23.2","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.7","Single Cell Type RNA - Paneth cells [nTPM]":"27.1","Single Cell Type RNA - Peritubular cells [nTPM]":"24.8","Single Cell Type RNA - Plasma cells [nTPM]":"28.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.9","Single Cell Type RNA - Spermatocytes [nTPM]":"71.5","Single Cell Type RNA - Spermatogonia [nTPM]":"38.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.1","Single Cell Type RNA - T-cells [nTPM]":"24.3","Single Cell Type RNA - Theca cells [nTPM]":"23.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.5","Single Cell Type RNA - Urothelial cells [nTPM]":"14.4"},{"Gene":"EIF2B5","Gene synonym":["EIF-2B","EIF2Bepsilon"],"Ensembl":"ENSG00000145191","Gene description":"Eukaryotic translation initiation factor 2B subunit epsilon","Uniprot":["Q13144"],"Chromosome":"3","Position":"184135038-184146127","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Initiation factor"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015412","HPA064370","HPA069303"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB015412":"AB_831253","HPA064370":"AB_2685249","HPA069303":"AB_2686114"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.38e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.1","Tissue RNA - adrenal gland [nTPM]":"18.9","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"8.2","Tissue RNA - basal ganglia [nTPM]":"10.1","Tissue RNA - bone marrow [nTPM]":"5.3","Tissue RNA - breast [nTPM]":"17.6","Tissue RNA - cerebellum [nTPM]":"11.2","Tissue RNA - cerebral cortex [nTPM]":"12.5","Tissue RNA - cervix [nTPM]":"17.2","Tissue RNA - choroid plexus [nTPM]":"13.0","Tissue RNA - colon [nTPM]":"19.6","Tissue RNA - duodenum [nTPM]":"9.4","Tissue RNA - endometrium 1 [nTPM]":"15.3","Tissue RNA - epididymis [nTPM]":"5.6","Tissue RNA - esophagus [nTPM]":"24.7","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"22.3","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"15.5","Tissue RNA - liver [nTPM]":"20.1","Tissue RNA - lung [nTPM]":"15.8","Tissue RNA - lymph node [nTPM]":"9.7","Tissue RNA - medulla oblongata [nTPM]":"11.2","Tissue RNA - midbrain [nTPM]":"10.1","Tissue RNA - ovary [nTPM]":"14.9","Tissue RNA - pancreas [nTPM]":"19.0","Tissue RNA - parathyroid gland [nTPM]":"22.1","Tissue RNA - pituitary gland [nTPM]":"18.0","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"10.6","Tissue RNA - prostate [nTPM]":"18.1","Tissue RNA - rectum [nTPM]":"13.8","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"23.9","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"53.9","Tissue RNA - skin 1 [nTPM]":"24.7","Tissue RNA - small intestine [nTPM]":"19.4","Tissue RNA - smooth muscle [nTPM]":"11.6","Tissue RNA - spinal cord [nTPM]":"10.9","Tissue RNA - spleen [nTPM]":"20.3","Tissue RNA - stomach 1 [nTPM]":"21.0","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"10.8","Tissue RNA - thymus [nTPM]":"18.2","Tissue RNA - thyroid gland [nTPM]":"16.7","Tissue RNA - tongue [nTPM]":"33.6","Tissue RNA - tonsil [nTPM]":"19.0","Tissue RNA - urinary bladder [nTPM]":"18.8","Tissue RNA - vagina [nTPM]":"19.6","Tissue RNA - white matter [nTPM]":"9.3","Cell RNA - A-431 [nTPM]":"60.7","Cell RNA - A549 [nTPM]":"25.4","Cell RNA - AF22 [nTPM]":"24.3","Cell RNA - AN3-CA [nTPM]":"25.4","Cell RNA - ASC diff [nTPM]":"32.4","Cell RNA - ASC TERT1 [nTPM]":"23.4","Cell RNA - BEWO [nTPM]":"28.0","Cell RNA - BJ [nTPM]":"29.1","Cell RNA - BJ hTERT+ [nTPM]":"36.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.4","Cell RNA - CACO-2 [nTPM]":"41.5","Cell RNA - CAPAN-2 [nTPM]":"24.5","Cell RNA - Daudi [nTPM]":"48.6","Cell RNA - EFO-21 [nTPM]":"37.8","Cell RNA - fHDF\/TERT166 [nTPM]":"32.5","Cell RNA - GAMG [nTPM]":"65.0","Cell RNA - HaCaT [nTPM]":"34.7","Cell RNA - HAP1 [nTPM]":"56.6","Cell RNA - HBEC3-KT [nTPM]":"39.1","Cell RNA - HBF TERT88 [nTPM]":"47.7","Cell RNA - HDLM-2 [nTPM]":"39.7","Cell RNA - HEK 293 [nTPM]":"55.4","Cell RNA - HEL [nTPM]":"75.6","Cell RNA - HeLa [nTPM]":"28.4","Cell RNA - Hep G2 [nTPM]":"42.4","Cell RNA - HHSteC [nTPM]":"24.8","Cell RNA - HL-60 [nTPM]":"61.8","Cell RNA - HMC-1 [nTPM]":"32.9","Cell RNA - HSkMC [nTPM]":"19.6","Cell RNA - hTCEpi [nTPM]":"32.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.7","Cell RNA - hTERT-HME1 [nTPM]":"24.1","Cell RNA - hTERT-RPE1 [nTPM]":"19.5","Cell RNA - HUVEC TERT2 [nTPM]":"37.3","Cell RNA - JURKAT [nTPM]":"49.7","Cell RNA - K-562 [nTPM]":"46.7","Cell RNA - Karpas-707 [nTPM]":"29.2","Cell RNA - LHCN-M2 [nTPM]":"35.2","Cell RNA - MCF7 [nTPM]":"49.5","Cell RNA - MOLT-4 [nTPM]":"49.5","Cell RNA - NB-4 [nTPM]":"34.3","Cell RNA - NTERA-2 [nTPM]":"39.9","Cell RNA - OE19 [nTPM]":"76.1","Cell RNA - PC-3 [nTPM]":"49.3","Cell RNA - REH [nTPM]":"45.1","Cell RNA - RH-30 [nTPM]":"37.6","Cell RNA - RPMI-8226 [nTPM]":"61.3","Cell RNA - RPTEC TERT1 [nTPM]":"43.1","Cell RNA - RT4 [nTPM]":"38.6","Cell RNA - SCLC-21H [nTPM]":"35.2","Cell RNA - SH-SY5Y [nTPM]":"34.2","Cell RNA - SiHa [nTPM]":"27.9","Cell RNA - SK-BR-3 [nTPM]":"91.9","Cell RNA - SK-MEL-30 [nTPM]":"41.5","Cell RNA - SuSa [nTPM]":"20.3","Cell RNA - T-47d [nTPM]":"83.6","Cell RNA - THP-1 [nTPM]":"60.8","Cell RNA - TIME [nTPM]":"33.6","Cell RNA - U-138 MG [nTPM]":"22.9","Cell RNA - U-2 OS [nTPM]":"35.4","Cell RNA - U-2197 [nTPM]":"28.5","Cell RNA - U-251 MG [nTPM]":"62.7","Cell RNA - U-266\/70 [nTPM]":"24.3","Cell RNA - U-266\/84 [nTPM]":"61.2","Cell RNA - U-698 [nTPM]":"69.6","Cell RNA - U-87 MG [nTPM]":"33.0","Cell RNA - U-937 [nTPM]":"58.8","Cell RNA - WM-115 [nTPM]":"35.2","Blood RNA - basophil [nTPM]":"9.5","Blood RNA - classical monocyte [nTPM]":"10.0","Blood RNA - eosinophil [nTPM]":"14.7","Blood RNA - gdT-cell [nTPM]":"8.7","Blood RNA - intermediate monocyte [nTPM]":"9.1","Blood RNA - MAIT T-cell [nTPM]":"11.5","Blood RNA - memory B-cell [nTPM]":"15.4","Blood RNA - memory CD4 T-cell [nTPM]":"12.2","Blood RNA - memory CD8 T-cell [nTPM]":"13.3","Blood RNA - myeloid DC [nTPM]":"11.8","Blood RNA - naive B-cell [nTPM]":"16.9","Blood RNA - naive CD4 T-cell [nTPM]":"18.1","Blood RNA - naive CD8 T-cell [nTPM]":"11.5","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"14.3","Blood RNA - non-classical monocyte [nTPM]":"9.8","Blood RNA - plasmacytoid DC [nTPM]":"5.1","Blood RNA - T-reg [nTPM]":"11.6","Blood RNA - total PBMC [nTPM]":"7.6","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"10.1","Brain RNA - cerebellum [nTPM]":"11.2","Brain RNA - cerebral cortex [nTPM]":"12.5","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"11.2","Brain RNA - midbrain [nTPM]":"10.1","Brain RNA - pons [nTPM]":"10.6","Brain RNA - spinal cord [nTPM]":"10.9","Brain RNA - thalamus [nTPM]":"10.8","Brain RNA - white matter [nTPM]":"9.3","Single Cell Type RNA - Adipocytes [nTPM]":"19.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.7","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"31.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.6","Single Cell Type RNA - Bipolar cells [nTPM]":"18.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"28.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.3","Single Cell Type RNA - dendritic cells [nTPM]":"25.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"27.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.7","Single Cell Type RNA - Endothelial cells [nTPM]":"24.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.9","Single Cell Type RNA - Erythroid cells [nTPM]":"27.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.8","Single Cell Type RNA - Fibroblasts [nTPM]":"17.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.3","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"21.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"27.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.9","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.0","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"22.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"18.2","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"30.8","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.3","Single Cell Type RNA - Paneth cells [nTPM]":"17.9","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"19.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.8","Single Cell Type RNA - Spermatocytes [nTPM]":"17.7","Single Cell Type RNA - Spermatogonia [nTPM]":"17.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.6","Single Cell Type RNA - T-cells [nTPM]":"26.5","Single Cell Type RNA - Theca cells [nTPM]":"34.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.7","Single Cell Type RNA - Urothelial cells [nTPM]":"44.9"},{"Gene":"EIF4G1","Gene synonym":["EIF4F","EIF4G","p220","PARK18"],"Ensembl":"ENSG00000114867","Gene description":"Eukaryotic translation initiation factor 4 gamma 1","Uniprot":["Q04637"],"Chromosome":"3","Position":"184314495-184335358","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Protein biosynthesis","Translation regulation"],"Molecular function":["Initiation factor","RNA-binding","Translational shunt"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"348.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB014774","HPA028487","HPA043866"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB014774":null,"HPA028487":"AB_10602219","HPA043866":"AB_2678705"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.99e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Tissue RNA - adipose tissue [nTPM]":"86.2","Tissue RNA - adrenal gland [nTPM]":"91.8","Tissue RNA - amygdala [nTPM]":"24.8","Tissue RNA - appendix [nTPM]":"75.7","Tissue RNA - basal ganglia [nTPM]":"22.2","Tissue RNA - bone marrow [nTPM]":"84.0","Tissue RNA - breast [nTPM]":"69.0","Tissue RNA - cerebellum [nTPM]":"17.9","Tissue RNA - cerebral cortex [nTPM]":"22.2","Tissue RNA - cervix [nTPM]":"66.6","Tissue RNA - choroid plexus [nTPM]":"34.1","Tissue RNA - colon [nTPM]":"81.8","Tissue RNA - duodenum [nTPM]":"62.0","Tissue RNA - endometrium 1 [nTPM]":"71.3","Tissue RNA - epididymis [nTPM]":"32.7","Tissue RNA - esophagus [nTPM]":"126.8","Tissue RNA - fallopian tube [nTPM]":"59.6","Tissue RNA - gallbladder [nTPM]":"50.9","Tissue RNA - heart muscle [nTPM]":"90.8","Tissue RNA - hippocampal formation [nTPM]":"23.3","Tissue RNA - hypothalamus [nTPM]":"29.8","Tissue RNA - kidney [nTPM]":"53.9","Tissue RNA - liver [nTPM]":"113.0","Tissue RNA - lung [nTPM]":"74.2","Tissue RNA - lymph node [nTPM]":"55.7","Tissue RNA - medulla oblongata [nTPM]":"38.5","Tissue RNA - midbrain [nTPM]":"36.1","Tissue RNA - ovary [nTPM]":"57.5","Tissue RNA - pancreas [nTPM]":"96.2","Tissue RNA - parathyroid gland [nTPM]":"99.3","Tissue RNA - pituitary gland [nTPM]":"57.4","Tissue RNA - placenta [nTPM]":"59.4","Tissue RNA - pons [nTPM]":"32.4","Tissue RNA - prostate [nTPM]":"62.2","Tissue RNA - rectum [nTPM]":"56.5","Tissue RNA - retina [nTPM]":"22.3","Tissue RNA - salivary gland [nTPM]":"93.1","Tissue RNA - seminal vesicle [nTPM]":"59.2","Tissue RNA - skeletal muscle [nTPM]":"348.3","Tissue RNA - skin 1 [nTPM]":"116.7","Tissue RNA - small intestine [nTPM]":"67.2","Tissue RNA - smooth muscle [nTPM]":"74.7","Tissue RNA - spinal cord [nTPM]":"24.4","Tissue RNA - spleen [nTPM]":"58.2","Tissue RNA - stomach 1 [nTPM]":"79.9","Tissue RNA - testis [nTPM]":"64.8","Tissue RNA - thalamus [nTPM]":"37.4","Tissue RNA - thymus [nTPM]":"49.1","Tissue RNA - thyroid gland [nTPM]":"71.3","Tissue RNA - tongue [nTPM]":"177.0","Tissue RNA - tonsil [nTPM]":"63.2","Tissue RNA - urinary bladder [nTPM]":"76.0","Tissue RNA - vagina [nTPM]":"85.3","Tissue RNA - white matter [nTPM]":"16.6","Cell RNA - A-431 [nTPM]":"559.0","Cell RNA - A549 [nTPM]":"232.3","Cell RNA - AF22 [nTPM]":"173.1","Cell RNA - AN3-CA [nTPM]":"205.7","Cell RNA - ASC diff [nTPM]":"196.9","Cell RNA - ASC TERT1 [nTPM]":"192.5","Cell RNA - BEWO [nTPM]":"322.5","Cell RNA - BJ [nTPM]":"298.6","Cell RNA - BJ hTERT+ [nTPM]":"204.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"315.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"238.8","Cell RNA - CACO-2 [nTPM]":"486.5","Cell RNA - CAPAN-2 [nTPM]":"173.7","Cell RNA - Daudi [nTPM]":"348.4","Cell RNA - EFO-21 [nTPM]":"381.9","Cell RNA - fHDF\/TERT166 [nTPM]":"367.6","Cell RNA - GAMG [nTPM]":"358.5","Cell RNA - HaCaT [nTPM]":"292.7","Cell RNA - HAP1 [nTPM]":"322.6","Cell RNA - HBEC3-KT [nTPM]":"365.8","Cell RNA - HBF TERT88 [nTPM]":"230.5","Cell RNA - HDLM-2 [nTPM]":"375.1","Cell RNA - HEK 293 [nTPM]":"345.8","Cell RNA - HEL [nTPM]":"321.3","Cell RNA - HeLa [nTPM]":"226.1","Cell RNA - Hep G2 [nTPM]":"206.4","Cell RNA - HHSteC [nTPM]":"173.4","Cell RNA - HL-60 [nTPM]":"321.4","Cell RNA - HMC-1 [nTPM]":"212.2","Cell RNA - HSkMC [nTPM]":"199.6","Cell RNA - hTCEpi [nTPM]":"206.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"292.4","Cell RNA - hTERT-HME1 [nTPM]":"268.8","Cell RNA - hTERT-RPE1 [nTPM]":"152.8","Cell RNA - HUVEC TERT2 [nTPM]":"278.3","Cell RNA - JURKAT [nTPM]":"128.8","Cell RNA - K-562 [nTPM]":"239.6","Cell RNA - Karpas-707 [nTPM]":"267.2","Cell RNA - LHCN-M2 [nTPM]":"205.7","Cell RNA - MCF7 [nTPM]":"403.4","Cell RNA - MOLT-4 [nTPM]":"219.7","Cell RNA - NB-4 [nTPM]":"105.3","Cell RNA - NTERA-2 [nTPM]":"368.9","Cell RNA - OE19 [nTPM]":"241.3","Cell RNA - PC-3 [nTPM]":"180.8","Cell RNA - REH [nTPM]":"221.7","Cell RNA - RH-30 [nTPM]":"183.4","Cell RNA - RPMI-8226 [nTPM]":"281.9","Cell RNA - RPTEC TERT1 [nTPM]":"156.8","Cell RNA - RT4 [nTPM]":"331.8","Cell RNA - SCLC-21H [nTPM]":"197.7","Cell RNA - SH-SY5Y [nTPM]":"174.6","Cell RNA - SiHa [nTPM]":"258.1","Cell RNA - SK-BR-3 [nTPM]":"415.6","Cell RNA - SK-MEL-30 [nTPM]":"187.6","Cell RNA - SuSa [nTPM]":"144.6","Cell RNA - T-47d [nTPM]":"445.2","Cell RNA - THP-1 [nTPM]":"206.5","Cell RNA - TIME [nTPM]":"364.1","Cell RNA - U-138 MG [nTPM]":"227.2","Cell RNA - U-2 OS [nTPM]":"228.9","Cell RNA - U-2197 [nTPM]":"297.3","Cell RNA - U-251 MG [nTPM]":"567.9","Cell RNA - U-266\/70 [nTPM]":"203.8","Cell RNA - U-266\/84 [nTPM]":"263.2","Cell RNA - U-698 [nTPM]":"629.0","Cell RNA - U-87 MG [nTPM]":"260.5","Cell RNA - U-937 [nTPM]":"271.4","Cell RNA - WM-115 [nTPM]":"258.3","Blood RNA - basophil [nTPM]":"8.3","Blood RNA - classical monocyte [nTPM]":"16.0","Blood RNA - eosinophil [nTPM]":"6.7","Blood RNA - gdT-cell [nTPM]":"11.7","Blood RNA - intermediate monocyte [nTPM]":"14.4","Blood RNA - MAIT T-cell [nTPM]":"10.8","Blood RNA - memory B-cell [nTPM]":"7.7","Blood RNA - memory CD4 T-cell [nTPM]":"7.8","Blood RNA - memory CD8 T-cell [nTPM]":"9.6","Blood RNA - myeloid DC [nTPM]":"12.8","Blood RNA - naive B-cell [nTPM]":"9.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.9","Blood RNA - naive CD8 T-cell [nTPM]":"7.6","Blood RNA - neutrophil [nTPM]":"5.6","Blood RNA - NK-cell [nTPM]":"8.7","Blood RNA - non-classical monocyte [nTPM]":"21.0","Blood RNA - plasmacytoid DC [nTPM]":"18.1","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"12.7","Brain RNA - amygdala [nTPM]":"24.8","Brain RNA - basal ganglia [nTPM]":"22.2","Brain RNA - cerebellum [nTPM]":"17.9","Brain RNA - cerebral cortex [nTPM]":"22.2","Brain RNA - hippocampal formation [nTPM]":"23.3","Brain RNA - hypothalamus [nTPM]":"29.8","Brain RNA - medulla oblongata [nTPM]":"38.5","Brain RNA - midbrain [nTPM]":"36.1","Brain RNA - pons [nTPM]":"32.4","Brain RNA - spinal cord [nTPM]":"24.4","Brain RNA - thalamus [nTPM]":"37.4","Brain RNA - white matter [nTPM]":"16.6","Single Cell Type RNA - Adipocytes [nTPM]":"63.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"72.6","Single Cell Type RNA - Astrocytes [nTPM]":"23.8","Single Cell Type RNA - B-cells [nTPM]":"41.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"59.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"78.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"58.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"70.6","Single Cell Type RNA - Bipolar cells [nTPM]":"24.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"69.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"46.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"109.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"72.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.0","Single Cell Type RNA - dendritic cells [nTPM]":"37.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"135.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"98.8","Single Cell Type RNA - Early spermatids [nTPM]":"151.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"53.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.1","Single Cell Type RNA - Endothelial cells [nTPM]":"69.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"55.7","Single Cell Type RNA - Erythroid cells [nTPM]":"82.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"135.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"74.8","Single Cell Type RNA - Fibroblasts [nTPM]":"64.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"75.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"85.6","Single Cell Type RNA - granulocytes [nTPM]":"48.0","Single Cell Type RNA - Granulosa cells [nTPM]":"163.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.5","Single Cell Type RNA - Hepatocytes [nTPM]":"152.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"66.8","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"97.2","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"40.8","Single Cell Type RNA - Langerhans cells [nTPM]":"39.9","Single Cell Type RNA - Late spermatids [nTPM]":"202.7","Single Cell Type RNA - Leydig cells [nTPM]":"73.0","Single Cell Type RNA - Macrophages [nTPM]":"48.9","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"53.0","Single Cell Type RNA - Muller glia cells [nTPM]":"23.2","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"149.0","Single Cell Type RNA - Paneth cells [nTPM]":"69.0","Single Cell Type RNA - Peritubular cells [nTPM]":"56.1","Single Cell Type RNA - Plasma cells [nTPM]":"112.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"96.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"77.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"45.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"51.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.2","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"81.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"78.9","Single Cell Type RNA - Spermatocytes [nTPM]":"24.8","Single Cell Type RNA - Spermatogonia [nTPM]":"41.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"120.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"91.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"79.6","Single Cell Type RNA - T-cells [nTPM]":"46.0","Single Cell Type RNA - Theca cells [nTPM]":"94.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"108.4","Single Cell Type RNA - Urothelial cells [nTPM]":"95.6"},{"Gene":"ELMOD3","Gene synonym":["DFNB88","FLJ21977","RBED1","RBM29"],"Ensembl":"ENSG00000115459","Gene description":"ELMO domain containing 3","Uniprot":["Q96FG2"],"Chromosome":"2","Position":"85354394-85391752","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012126"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA012126":"AB_1848130"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.85e-5"},"Tissue RNA - adipose tissue [nTPM]":"11.1","Tissue RNA - adrenal gland [nTPM]":"8.2","Tissue RNA - amygdala [nTPM]":"7.0","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"8.7","Tissue RNA - cerebellum [nTPM]":"6.6","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"7.2","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"7.6","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"5.9","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"6.9","Tissue RNA - gallbladder [nTPM]":"6.1","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"6.0","Tissue RNA - liver [nTPM]":"8.8","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"6.5","Tissue RNA - pancreas [nTPM]":"6.0","Tissue RNA - parathyroid gland [nTPM]":"8.9","Tissue RNA - pituitary gland [nTPM]":"6.6","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"8.4","Tissue RNA - rectum [nTPM]":"4.9","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"6.7","Tissue RNA - spinal cord [nTPM]":"6.4","Tissue RNA - spleen [nTPM]":"6.6","Tissue RNA - stomach 1 [nTPM]":"7.1","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"6.7","Tissue RNA - thymus [nTPM]":"5.4","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"10.2","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"7.0","Cell RNA - A-431 [nTPM]":"4.9","Cell RNA - A549 [nTPM]":"6.0","Cell RNA - AF22 [nTPM]":"6.7","Cell RNA - AN3-CA [nTPM]":"10.0","Cell RNA - ASC diff [nTPM]":"20.9","Cell RNA - ASC TERT1 [nTPM]":"9.2","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"8.6","Cell RNA - BJ hTERT+ [nTPM]":"6.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.7","Cell RNA - CACO-2 [nTPM]":"5.0","Cell RNA - CAPAN-2 [nTPM]":"2.4","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"6.7","Cell RNA - fHDF\/TERT166 [nTPM]":"7.2","Cell RNA - GAMG [nTPM]":"15.9","Cell RNA - HaCaT [nTPM]":"5.1","Cell RNA - HAP1 [nTPM]":"9.7","Cell RNA - HBEC3-KT [nTPM]":"11.9","Cell RNA - HBF TERT88 [nTPM]":"11.4","Cell RNA - HDLM-2 [nTPM]":"13.0","Cell RNA - HEK 293 [nTPM]":"6.7","Cell RNA - HEL [nTPM]":"6.5","Cell RNA - HeLa [nTPM]":"3.4","Cell RNA - Hep G2 [nTPM]":"3.7","Cell RNA - HHSteC [nTPM]":"10.9","Cell RNA - HL-60 [nTPM]":"4.9","Cell RNA - HMC-1 [nTPM]":"8.2","Cell RNA - HSkMC [nTPM]":"9.6","Cell RNA - hTCEpi [nTPM]":"10.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.1","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"10.6","Cell RNA - HUVEC TERT2 [nTPM]":"9.1","Cell RNA - JURKAT [nTPM]":"7.4","Cell RNA - K-562 [nTPM]":"6.6","Cell RNA - Karpas-707 [nTPM]":"4.2","Cell RNA - LHCN-M2 [nTPM]":"11.9","Cell RNA - MCF7 [nTPM]":"3.9","Cell RNA - MOLT-4 [nTPM]":"7.2","Cell RNA - NB-4 [nTPM]":"2.9","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"9.8","Cell RNA - PC-3 [nTPM]":"6.4","Cell RNA - REH [nTPM]":"5.2","Cell RNA - RH-30 [nTPM]":"13.9","Cell RNA - RPMI-8226 [nTPM]":"3.5","Cell RNA - RPTEC TERT1 [nTPM]":"5.8","Cell RNA - RT4 [nTPM]":"3.0","Cell RNA - SCLC-21H [nTPM]":"6.3","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"5.3","Cell RNA - SK-BR-3 [nTPM]":"7.3","Cell RNA - SK-MEL-30 [nTPM]":"7.9","Cell RNA - SuSa [nTPM]":"7.6","Cell RNA - T-47d [nTPM]":"4.0","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"4.8","Cell RNA - U-138 MG [nTPM]":"9.1","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"7.9","Cell RNA - U-251 MG [nTPM]":"8.0","Cell RNA - U-266\/70 [nTPM]":"5.0","Cell RNA - U-266\/84 [nTPM]":"9.9","Cell RNA - U-698 [nTPM]":"4.9","Cell RNA - U-87 MG [nTPM]":"9.1","Cell RNA - U-937 [nTPM]":"5.7","Cell RNA - WM-115 [nTPM]":"9.4","Blood RNA - basophil [nTPM]":"6.5","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"8.0","Blood RNA - gdT-cell [nTPM]":"5.0","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"3.1","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"3.2","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"5.0","Blood RNA - non-classical monocyte [nTPM]":"4.5","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"2.8","Brain RNA - amygdala [nTPM]":"7.0","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"6.6","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"6.4","Brain RNA - thalamus [nTPM]":"6.7","Brain RNA - white matter [nTPM]":"7.0","Single Cell Type RNA - Adipocytes [nTPM]":"9.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"36.9","Single Cell Type RNA - B-cells [nTPM]":"15.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"27.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"16.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - dendritic cells [nTPM]":"9.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.6","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.9","Single Cell Type RNA - Endothelial cells [nTPM]":"9.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.9","Single Cell Type RNA - Fibroblasts [nTPM]":"10.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"20.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"7.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.6","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.0","Single Cell Type RNA - Langerhans cells [nTPM]":"9.3","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"9.5","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"16.5","Single Cell Type RNA - Muller glia cells [nTPM]":"14.1","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"49.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.4","Single Cell Type RNA - Paneth cells [nTPM]":"15.3","Single Cell Type RNA - Peritubular cells [nTPM]":"23.7","Single Cell Type RNA - Plasma cells [nTPM]":"7.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.0","Single Cell Type RNA - Spermatocytes [nTPM]":"19.7","Single Cell Type RNA - Spermatogonia [nTPM]":"10.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - T-cells [nTPM]":"14.0","Single Cell Type RNA - Theca cells [nTPM]":"18.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.7","Single Cell Type RNA - Urothelial cells [nTPM]":"9.4"},{"Gene":"ELOVL4","Gene synonym":["CT118","SCA34","STGD2","STGD3"],"Ensembl":"ENSG00000118402","Gene description":"ELOVL fatty acid elongase 4","Uniprot":["Q9GZR5"],"Chromosome":"6","Position":"79914814-79947553","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets","Ichthyosis","Mental retardation","Neurodegeneration","Spinocerebellar ataxia","Stargardt disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"105.5","retina":"176.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"63.8","Cone photoreceptor cells":"148.0","Excitatory neurons":"55.3","Rod photoreceptor cells":"355.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"MAIT T-cell":"23.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"238","RNA blood lineage specific nTPM":{"T-cells":"23.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"JURKAT":"41.2","MOLT-4":"32.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.27e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"7.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"4.1","Tissue RNA - cerebellum [nTPM]":"10.0","Tissue RNA - cerebral cortex [nTPM]":"15.4","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"9.7","Tissue RNA - colon [nTPM]":"1.8","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"10.6","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"9.9","Tissue RNA - kidney [nTPM]":"1.5","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"14.4","Tissue RNA - midbrain [nTPM]":"5.3","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"10.8","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"15.0","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"176.7","Tissue RNA - salivary gland [nTPM]":"2.8","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"43.1","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"2.7","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"5.7","Tissue RNA - thalamus [nTPM]":"7.4","Tissue RNA - thymus [nTPM]":"105.5","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"7.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"10.8","Cell RNA - AN3-CA [nTPM]":"12.0","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"8.5","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"5.6","Cell RNA - BJ hTERT+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.2","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"7.7","Cell RNA - GAMG [nTPM]":"19.3","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"14.1","Cell RNA - HBEC3-KT [nTPM]":"7.9","Cell RNA - HBF TERT88 [nTPM]":"3.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"18.2","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"2.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"4.4","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"6.9","Cell RNA - hTCEpi [nTPM]":"2.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.8","Cell RNA - hTERT-HME1 [nTPM]":"4.9","Cell RNA - hTERT-RPE1 [nTPM]":"6.8","Cell RNA - HUVEC TERT2 [nTPM]":"7.8","Cell RNA - JURKAT [nTPM]":"41.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"10.0","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"32.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"5.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"4.2","Cell RNA - SiHa [nTPM]":"6.0","Cell RNA - SK-BR-3 [nTPM]":"9.6","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"7.4","Cell RNA - T-47d [nTPM]":"3.8","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"2.1","Cell RNA - U-2 OS [nTPM]":"4.1","Cell RNA - U-2197 [nTPM]":"3.2","Cell RNA - U-251 MG [nTPM]":"4.3","Cell RNA - U-266\/70 [nTPM]":"7.2","Cell RNA - U-266\/84 [nTPM]":"15.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"23.7","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"7.0","Brain RNA - cerebellum [nTPM]":"10.0","Brain RNA - cerebral cortex [nTPM]":"15.4","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"9.9","Brain RNA - medulla oblongata [nTPM]":"14.4","Brain RNA - midbrain [nTPM]":"5.3","Brain RNA - pons [nTPM]":"15.0","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"7.4","Brain RNA - white matter [nTPM]":"7.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"63.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"148.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"55.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"50.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"355.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"15.4","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"37.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"ELOVL5","Gene synonym":["dJ483K16.1","HELO1","SCA38"],"Ensembl":"ENSG00000012660","Gene description":"ELOVL fatty acid elongase 5","Uniprot":["Q9NYP7"],"Chromosome":"6","Position":"53267398-53349179","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017042","HPA047752","HPA054197"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB017042":null,"HPA047752":"AB_2680147","HPA054197":"AB_2682413"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.80e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"242.4","Tissue RNA - adrenal gland [nTPM]":"134.7","Tissue RNA - amygdala [nTPM]":"51.3","Tissue RNA - appendix [nTPM]":"74.9","Tissue RNA - basal ganglia [nTPM]":"67.0","Tissue RNA - bone marrow [nTPM]":"114.6","Tissue RNA - breast [nTPM]":"199.2","Tissue RNA - cerebellum [nTPM]":"74.6","Tissue RNA - cerebral cortex [nTPM]":"79.2","Tissue RNA - cervix [nTPM]":"48.9","Tissue RNA - choroid plexus [nTPM]":"49.4","Tissue RNA - colon [nTPM]":"40.0","Tissue RNA - duodenum [nTPM]":"28.3","Tissue RNA - endometrium 1 [nTPM]":"39.8","Tissue RNA - epididymis [nTPM]":"49.7","Tissue RNA - esophagus [nTPM]":"28.4","Tissue RNA - fallopian tube [nTPM]":"46.0","Tissue RNA - gallbladder [nTPM]":"51.3","Tissue RNA - heart muscle [nTPM]":"37.8","Tissue RNA - hippocampal formation [nTPM]":"50.8","Tissue RNA - hypothalamus [nTPM]":"65.3","Tissue RNA - kidney [nTPM]":"38.9","Tissue RNA - liver [nTPM]":"108.9","Tissue RNA - lung [nTPM]":"68.4","Tissue RNA - lymph node [nTPM]":"106.7","Tissue RNA - medulla oblongata [nTPM]":"80.7","Tissue RNA - midbrain [nTPM]":"69.0","Tissue RNA - ovary [nTPM]":"32.3","Tissue RNA - pancreas [nTPM]":"15.4","Tissue RNA - parathyroid gland [nTPM]":"24.3","Tissue RNA - pituitary gland [nTPM]":"28.5","Tissue RNA - placenta [nTPM]":"40.2","Tissue RNA - pons [nTPM]":"74.5","Tissue RNA - prostate [nTPM]":"128.0","Tissue RNA - rectum [nTPM]":"18.3","Tissue RNA - retina [nTPM]":"36.5","Tissue RNA - salivary gland [nTPM]":"24.8","Tissue RNA - seminal vesicle [nTPM]":"103.0","Tissue RNA - skeletal muscle [nTPM]":"9.9","Tissue RNA - skin 1 [nTPM]":"32.9","Tissue RNA - small intestine [nTPM]":"47.5","Tissue RNA - smooth muscle [nTPM]":"52.4","Tissue RNA - spinal cord [nTPM]":"67.7","Tissue RNA - spleen [nTPM]":"56.1","Tissue RNA - stomach 1 [nTPM]":"22.8","Tissue RNA - testis [nTPM]":"82.5","Tissue RNA - thalamus [nTPM]":"65.8","Tissue RNA - thymus [nTPM]":"107.3","Tissue RNA - thyroid gland [nTPM]":"45.1","Tissue RNA - tongue [nTPM]":"19.5","Tissue RNA - tonsil [nTPM]":"102.4","Tissue RNA - urinary bladder [nTPM]":"67.1","Tissue RNA - vagina [nTPM]":"27.0","Tissue RNA - white matter [nTPM]":"98.9","Cell RNA - A-431 [nTPM]":"137.2","Cell RNA - A549 [nTPM]":"98.1","Cell RNA - AF22 [nTPM]":"168.0","Cell RNA - AN3-CA [nTPM]":"309.0","Cell RNA - ASC diff [nTPM]":"436.0","Cell RNA - ASC TERT1 [nTPM]":"250.8","Cell RNA - BEWO [nTPM]":"71.3","Cell RNA - BJ [nTPM]":"155.8","Cell RNA - BJ hTERT+ [nTPM]":"174.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"123.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"171.5","Cell RNA - CACO-2 [nTPM]":"87.4","Cell RNA - CAPAN-2 [nTPM]":"154.5","Cell RNA - Daudi [nTPM]":"154.4","Cell RNA - EFO-21 [nTPM]":"110.3","Cell RNA - fHDF\/TERT166 [nTPM]":"163.3","Cell RNA - GAMG [nTPM]":"193.1","Cell RNA - HaCaT [nTPM]":"78.9","Cell RNA - HAP1 [nTPM]":"168.0","Cell RNA - HBEC3-KT [nTPM]":"142.6","Cell RNA - HBF TERT88 [nTPM]":"183.7","Cell RNA - HDLM-2 [nTPM]":"131.2","Cell RNA - HEK 293 [nTPM]":"117.5","Cell RNA - HEL [nTPM]":"153.1","Cell RNA - HeLa [nTPM]":"85.0","Cell RNA - Hep G2 [nTPM]":"122.9","Cell RNA - HHSteC [nTPM]":"239.0","Cell RNA - HL-60 [nTPM]":"122.2","Cell RNA - HMC-1 [nTPM]":"107.2","Cell RNA - HSkMC [nTPM]":"233.6","Cell RNA - hTCEpi [nTPM]":"109.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"123.6","Cell RNA - hTERT-HME1 [nTPM]":"153.9","Cell RNA - hTERT-RPE1 [nTPM]":"124.5","Cell RNA - HUVEC TERT2 [nTPM]":"139.1","Cell RNA - JURKAT [nTPM]":"301.4","Cell RNA - K-562 [nTPM]":"194.2","Cell RNA - Karpas-707 [nTPM]":"87.3","Cell RNA - LHCN-M2 [nTPM]":"90.3","Cell RNA - MCF7 [nTPM]":"14.9","Cell RNA - MOLT-4 [nTPM]":"364.4","Cell RNA - NB-4 [nTPM]":"107.9","Cell RNA - NTERA-2 [nTPM]":"91.2","Cell RNA - OE19 [nTPM]":"5.2","Cell RNA - PC-3 [nTPM]":"73.6","Cell RNA - REH [nTPM]":"139.9","Cell RNA - RH-30 [nTPM]":"115.3","Cell RNA - RPMI-8226 [nTPM]":"54.3","Cell RNA - RPTEC TERT1 [nTPM]":"232.7","Cell RNA - RT4 [nTPM]":"80.6","Cell RNA - SCLC-21H [nTPM]":"155.7","Cell RNA - SH-SY5Y [nTPM]":"107.1","Cell RNA - SiHa [nTPM]":"129.3","Cell RNA - SK-BR-3 [nTPM]":"66.9","Cell RNA - SK-MEL-30 [nTPM]":"135.2","Cell RNA - SuSa [nTPM]":"108.7","Cell RNA - T-47d [nTPM]":"152.3","Cell RNA - THP-1 [nTPM]":"112.9","Cell RNA - TIME [nTPM]":"133.0","Cell RNA - U-138 MG [nTPM]":"134.7","Cell RNA - U-2 OS [nTPM]":"118.5","Cell RNA - U-2197 [nTPM]":"242.2","Cell RNA - U-251 MG [nTPM]":"208.8","Cell RNA - U-266\/70 [nTPM]":"72.8","Cell RNA - U-266\/84 [nTPM]":"72.1","Cell RNA - U-698 [nTPM]":"116.2","Cell RNA - U-87 MG [nTPM]":"70.2","Cell RNA - U-937 [nTPM]":"173.6","Cell RNA - WM-115 [nTPM]":"97.8","Blood RNA - basophil [nTPM]":"47.6","Blood RNA - classical monocyte [nTPM]":"49.2","Blood RNA - eosinophil [nTPM]":"183.7","Blood RNA - gdT-cell [nTPM]":"34.9","Blood RNA - intermediate monocyte [nTPM]":"34.9","Blood RNA - MAIT T-cell [nTPM]":"56.5","Blood RNA - memory B-cell [nTPM]":"88.4","Blood RNA - memory CD4 T-cell [nTPM]":"58.1","Blood RNA - memory CD8 T-cell [nTPM]":"42.7","Blood RNA - myeloid DC [nTPM]":"77.9","Blood RNA - naive B-cell [nTPM]":"101.5","Blood RNA - naive CD4 T-cell [nTPM]":"27.8","Blood RNA - naive CD8 T-cell [nTPM]":"26.3","Blood RNA - neutrophil [nTPM]":"261.5","Blood RNA - NK-cell [nTPM]":"36.7","Blood RNA - non-classical monocyte [nTPM]":"45.0","Blood RNA - plasmacytoid DC [nTPM]":"20.4","Blood RNA - T-reg [nTPM]":"110.0","Blood RNA - total PBMC [nTPM]":"50.6","Brain RNA - amygdala [nTPM]":"51.3","Brain RNA - basal ganglia [nTPM]":"67.0","Brain RNA - cerebellum [nTPM]":"74.6","Brain RNA - cerebral cortex [nTPM]":"79.2","Brain RNA - hippocampal formation [nTPM]":"50.8","Brain RNA - hypothalamus [nTPM]":"65.3","Brain RNA - medulla oblongata [nTPM]":"80.7","Brain RNA - midbrain [nTPM]":"69.0","Brain RNA - pons [nTPM]":"74.5","Brain RNA - spinal cord [nTPM]":"67.7","Brain RNA - thalamus [nTPM]":"65.8","Brain RNA - white matter [nTPM]":"98.9","Single Cell Type RNA - Adipocytes [nTPM]":"48.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"50.7","Single Cell Type RNA - Astrocytes [nTPM]":"75.4","Single Cell Type RNA - B-cells [nTPM]":"118.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"108.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"177.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"70.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"40.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - dendritic cells [nTPM]":"55.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"34.9","Single Cell Type RNA - Early spermatids [nTPM]":"94.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"53.2","Single Cell Type RNA - Endothelial cells [nTPM]":"54.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.0","Single Cell Type RNA - Erythroid cells [nTPM]":"77.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.2","Single Cell Type RNA - Fibroblasts [nTPM]":"54.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"66.4","Single Cell Type RNA - granulocytes [nTPM]":"99.0","Single Cell Type RNA - Granulosa cells [nTPM]":"28.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"39.3","Single Cell Type RNA - Hepatocytes [nTPM]":"88.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.5","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"57.3","Single Cell Type RNA - Langerhans cells [nTPM]":"114.6","Single Cell Type RNA - Late spermatids [nTPM]":"181.0","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"55.5","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"53.5","Single Cell Type RNA - Muller glia cells [nTPM]":"83.2","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"111.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"32.0","Single Cell Type RNA - Plasma cells [nTPM]":"45.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"169.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"58.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"77.5","Single Cell Type RNA - Spermatocytes [nTPM]":"27.0","Single Cell Type RNA - Spermatogonia [nTPM]":"18.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"60.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"97.2","Single Cell Type RNA - Theca cells [nTPM]":"60.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"73.4"},{"Gene":"ELP1","Gene synonym":["DYS","IKAP","IKBKAP","IKI3","TOT1"],"Ensembl":"ENSG00000070061","Gene description":"Elongator complex protein 1","Uniprot":["O95163"],"Chromosome":"9","Position":"108866898-108934328","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","tRNA processing"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"12.8","Alveolar cells type 2":"18.8","Collecting duct cells":"14.7","Exocrine glandular cells":"21.1","Theca cells":"24.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"36.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"36.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB021340","HPA049677","HPA050686"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB021340":null,"HPA049677":"AB_2680847","HPA050686":"AB_2681216"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.57e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.6","Tissue RNA - adrenal gland [nTPM]":"39.7","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"6.5","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"6.9","Tissue RNA - cerebral cortex [nTPM]":"8.1","Tissue RNA - cervix [nTPM]":"21.5","Tissue RNA - choroid plexus [nTPM]":"8.4","Tissue RNA - colon [nTPM]":"17.5","Tissue RNA - duodenum [nTPM]":"5.8","Tissue RNA - endometrium 1 [nTPM]":"17.1","Tissue RNA - epididymis [nTPM]":"9.5","Tissue RNA - esophagus [nTPM]":"13.0","Tissue RNA - fallopian tube [nTPM]":"19.9","Tissue RNA - gallbladder [nTPM]":"6.7","Tissue RNA - heart muscle [nTPM]":"18.2","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"7.8","Tissue RNA - kidney [nTPM]":"14.4","Tissue RNA - liver [nTPM]":"18.4","Tissue RNA - lung [nTPM]":"15.2","Tissue RNA - lymph node [nTPM]":"9.6","Tissue RNA - medulla oblongata [nTPM]":"6.6","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"29.9","Tissue RNA - pancreas [nTPM]":"17.6","Tissue RNA - parathyroid gland [nTPM]":"29.3","Tissue RNA - pituitary gland [nTPM]":"38.1","Tissue RNA - placenta [nTPM]":"6.8","Tissue RNA - pons [nTPM]":"7.9","Tissue RNA - prostate [nTPM]":"18.0","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"24.8","Tissue RNA - salivary gland [nTPM]":"14.8","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"15.7","Tissue RNA - skin 1 [nTPM]":"15.9","Tissue RNA - small intestine [nTPM]":"15.9","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"18.2","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"12.0","Tissue RNA - thalamus [nTPM]":"6.9","Tissue RNA - thymus [nTPM]":"9.5","Tissue RNA - thyroid gland [nTPM]":"20.1","Tissue RNA - tongue [nTPM]":"11.4","Tissue RNA - tonsil [nTPM]":"8.8","Tissue RNA - urinary bladder [nTPM]":"15.5","Tissue RNA - vagina [nTPM]":"18.3","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"15.6","Cell RNA - A549 [nTPM]":"26.7","Cell RNA - AF22 [nTPM]":"19.7","Cell RNA - AN3-CA [nTPM]":"12.8","Cell RNA - ASC diff [nTPM]":"21.7","Cell RNA - ASC TERT1 [nTPM]":"21.1","Cell RNA - BEWO [nTPM]":"21.1","Cell RNA - BJ [nTPM]":"23.4","Cell RNA - BJ hTERT+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.9","Cell RNA - CACO-2 [nTPM]":"31.5","Cell RNA - CAPAN-2 [nTPM]":"9.2","Cell RNA - Daudi [nTPM]":"31.0","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"20.2","Cell RNA - GAMG [nTPM]":"27.5","Cell RNA - HaCaT [nTPM]":"35.7","Cell RNA - HAP1 [nTPM]":"40.7","Cell RNA - HBEC3-KT [nTPM]":"29.8","Cell RNA - HBF TERT88 [nTPM]":"25.8","Cell RNA - HDLM-2 [nTPM]":"28.6","Cell RNA - HEK 293 [nTPM]":"26.6","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"38.2","Cell RNA - Hep G2 [nTPM]":"63.3","Cell RNA - HHSteC [nTPM]":"18.6","Cell RNA - HL-60 [nTPM]":"28.7","Cell RNA - HMC-1 [nTPM]":"13.7","Cell RNA - HSkMC [nTPM]":"18.7","Cell RNA - hTCEpi [nTPM]":"19.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.5","Cell RNA - hTERT-HME1 [nTPM]":"26.7","Cell RNA - hTERT-RPE1 [nTPM]":"18.0","Cell RNA - HUVEC TERT2 [nTPM]":"20.9","Cell RNA - JURKAT [nTPM]":"33.6","Cell RNA - K-562 [nTPM]":"43.1","Cell RNA - Karpas-707 [nTPM]":"17.9","Cell RNA - LHCN-M2 [nTPM]":"22.9","Cell RNA - MCF7 [nTPM]":"25.3","Cell RNA - MOLT-4 [nTPM]":"21.2","Cell RNA - NB-4 [nTPM]":"13.6","Cell RNA - NTERA-2 [nTPM]":"32.1","Cell RNA - OE19 [nTPM]":"41.0","Cell RNA - PC-3 [nTPM]":"34.4","Cell RNA - REH [nTPM]":"20.7","Cell RNA - RH-30 [nTPM]":"31.9","Cell RNA - RPMI-8226 [nTPM]":"18.3","Cell RNA - RPTEC TERT1 [nTPM]":"17.3","Cell RNA - RT4 [nTPM]":"16.1","Cell RNA - SCLC-21H [nTPM]":"26.6","Cell RNA - SH-SY5Y [nTPM]":"23.9","Cell RNA - SiHa [nTPM]":"27.8","Cell RNA - SK-BR-3 [nTPM]":"23.3","Cell RNA - SK-MEL-30 [nTPM]":"15.7","Cell RNA - SuSa [nTPM]":"22.4","Cell RNA - T-47d [nTPM]":"33.3","Cell RNA - THP-1 [nTPM]":"14.1","Cell RNA - TIME [nTPM]":"15.4","Cell RNA - U-138 MG [nTPM]":"10.4","Cell RNA - U-2 OS [nTPM]":"16.2","Cell RNA - U-2197 [nTPM]":"26.0","Cell RNA - U-251 MG [nTPM]":"25.1","Cell RNA - U-266\/70 [nTPM]":"15.5","Cell RNA - U-266\/84 [nTPM]":"47.2","Cell RNA - U-698 [nTPM]":"13.8","Cell RNA - U-87 MG [nTPM]":"20.0","Cell RNA - U-937 [nTPM]":"20.2","Cell RNA - WM-115 [nTPM]":"19.1","Blood RNA - basophil [nTPM]":"36.6","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"2.9","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"4.4","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"3.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"4.5","Blood RNA - non-classical monocyte [nTPM]":"3.3","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"6.9","Brain RNA - cerebral cortex [nTPM]":"8.1","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"7.8","Brain RNA - medulla oblongata [nTPM]":"6.6","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"7.9","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"6.9","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"7.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.9","Single Cell Type RNA - dendritic cells [nTPM]":"5.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.6","Single Cell Type RNA - Endothelial cells [nTPM]":"4.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.6","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"11.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"24.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ENTPD1","Gene synonym":["ATPDase","CD39","NTPDase-1","SPG64"],"Ensembl":"ENSG00000138185","Gene description":"Ectonucleoside triphosphate diphosphohydrolase 1","Uniprot":["P49961"],"Chromosome":"10","Position":"95711779-95877266","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"74.1","Kupffer cells":"110.4","Langerhans cells":"161.3","Microglial cells":"217.4","monocytes":"112.2","Plasma cells":"80.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"17.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"102.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"31.9","granulocytes":"102.2","monocytes":"41.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"HDLM-2":"147.5","Karpas-707":"135.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002494","HPA014067","CAB079986"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB002494":"AB_563557","CAB079986":null,"HPA014067":"AB_1848178"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.33e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.89e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"24.7","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"27.5","Tissue RNA - breast [nTPM]":"10.8","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"14.3","Tissue RNA - duodenum [nTPM]":"9.3","Tissue RNA - endometrium 1 [nTPM]":"28.0","Tissue RNA - epididymis [nTPM]":"19.3","Tissue RNA - esophagus [nTPM]":"19.2","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"27.7","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"7.6","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"16.1","Tissue RNA - lymph node [nTPM]":"20.2","Tissue RNA - medulla oblongata [nTPM]":"7.1","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"3.9","Tissue RNA - placenta [nTPM]":"11.4","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"12.8","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"18.1","Tissue RNA - skeletal muscle [nTPM]":"4.0","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"11.7","Tissue RNA - smooth muscle [nTPM]":"49.7","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"21.5","Tissue RNA - stomach 1 [nTPM]":"7.3","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"7.5","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"20.0","Tissue RNA - tongue [nTPM]":"8.7","Tissue RNA - tonsil [nTPM]":"25.6","Tissue RNA - urinary bladder [nTPM]":"30.6","Tissue RNA - vagina [nTPM]":"11.0","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"2.7","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"5.0","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"4.0","Cell RNA - CAPAN-2 [nTPM]":"1.6","Cell RNA - Daudi [nTPM]":"8.2","Cell RNA - EFO-21 [nTPM]":"3.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"5.3","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"147.5","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"7.2","Cell RNA - HeLa [nTPM]":"4.0","Cell RNA - Hep G2 [nTPM]":"4.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"12.5","Cell RNA - HMC-1 [nTPM]":"4.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.4","Cell RNA - HUVEC TERT2 [nTPM]":"18.2","Cell RNA - JURKAT [nTPM]":"2.0","Cell RNA - K-562 [nTPM]":"5.3","Cell RNA - Karpas-707 [nTPM]":"135.4","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"4.7","Cell RNA - NB-4 [nTPM]":"5.8","Cell RNA - NTERA-2 [nTPM]":"5.9","Cell RNA - OE19 [nTPM]":"3.6","Cell RNA - PC-3 [nTPM]":"2.8","Cell RNA - REH [nTPM]":"15.3","Cell RNA - RH-30 [nTPM]":"2.4","Cell RNA - RPMI-8226 [nTPM]":"4.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"6.2","Cell RNA - SiHa [nTPM]":"3.6","Cell RNA - SK-BR-3 [nTPM]":"3.7","Cell RNA - SK-MEL-30 [nTPM]":"3.9","Cell RNA - SuSa [nTPM]":"3.6","Cell RNA - T-47d [nTPM]":"5.5","Cell RNA - THP-1 [nTPM]":"5.9","Cell RNA - TIME [nTPM]":"3.9","Cell RNA - U-138 MG [nTPM]":"3.9","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"5.3","Cell RNA - U-266\/70 [nTPM]":"21.6","Cell RNA - U-266\/84 [nTPM]":"7.2","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"4.3","Cell RNA - U-937 [nTPM]":"13.9","Cell RNA - WM-115 [nTPM]":"2.7","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"41.0","Blood RNA - eosinophil [nTPM]":"102.2","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"27.2","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"13.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"31.9","Blood RNA - naive B-cell [nTPM]":"11.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"49.4","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"6.7","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"13.1","Blood RNA - total PBMC [nTPM]":"15.5","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"7.1","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"7.5","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"19.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"74.1","Single Cell Type RNA - B-cells [nTPM]":"40.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"10.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.6","Single Cell Type RNA - Endothelial cells [nTPM]":"60.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"15.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"110.4","Single Cell Type RNA - Langerhans cells [nTPM]":"161.3","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"62.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"217.4","Single Cell Type RNA - monocytes [nTPM]":"112.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"80.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.7","Single Cell Type RNA - Spermatocytes [nTPM]":"10.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - T-cells [nTPM]":"26.9","Single Cell Type RNA - Theca cells [nTPM]":"15.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"EPHA2","Gene synonym":["ECK"],"Ensembl":"ENSG00000142627","Gene description":"EPH receptor A2","Uniprot":["P29317"],"Chromosome":"1","Position":"16124337-16156069","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis","Apoptosis","Cell adhesion","Differentiation","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Cataract","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"147.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"202.3","Glandular and luminal cells":"182.9","Squamous epithelial cells":"156.3","Suprabasal keratinocytes":"248.3","Urothelial cells":"200.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"94","RNA blood cell specific nTPM":{"plasmacytoid DC":"9.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"94","RNA blood lineage specific nTPM":{"dendritic cells":"9.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"201.1","PC-3":"229.0","U-251 MG":"242.1","WM-115":"258.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010464"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Golgi apparatus","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nuclear speckles","Golgi apparatus"],"Antibody RRID":{"CAB010464":"AB_631436"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.4","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"4.8","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"14.6","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"38.2","Tissue RNA - choroid plexus [nTPM]":"11.7","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"10.0","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"147.9","Tissue RNA - fallopian tube [nTPM]":"13.5","Tissue RNA - gallbladder [nTPM]":"28.2","Tissue RNA - heart muscle [nTPM]":"15.8","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"18.7","Tissue RNA - liver [nTPM]":"18.9","Tissue RNA - lung [nTPM]":"17.9","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"5.8","Tissue RNA - pancreas [nTPM]":"23.2","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"7.4","Tissue RNA - placenta [nTPM]":"14.0","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"67.7","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"40.3","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"15.6","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"15.2","Tissue RNA - tongue [nTPM]":"5.1","Tissue RNA - tonsil [nTPM]":"11.1","Tissue RNA - urinary bladder [nTPM]":"56.1","Tissue RNA - vagina [nTPM]":"58.8","Tissue RNA - white matter [nTPM]":"3.1","Cell RNA - A-431 [nTPM]":"76.9","Cell RNA - A549 [nTPM]":"151.7","Cell RNA - AF22 [nTPM]":"41.4","Cell RNA - AN3-CA [nTPM]":"20.1","Cell RNA - ASC diff [nTPM]":"2.9","Cell RNA - ASC TERT1 [nTPM]":"3.5","Cell RNA - BEWO [nTPM]":"24.3","Cell RNA - BJ [nTPM]":"45.2","Cell RNA - BJ hTERT+ [nTPM]":"63.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"79.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"50.6","Cell RNA - CACO-2 [nTPM]":"63.9","Cell RNA - CAPAN-2 [nTPM]":"201.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"189.8","Cell RNA - fHDF\/TERT166 [nTPM]":"25.9","Cell RNA - GAMG [nTPM]":"98.8","Cell RNA - HaCaT [nTPM]":"30.6","Cell RNA - HAP1 [nTPM]":"9.9","Cell RNA - HBEC3-KT [nTPM]":"104.4","Cell RNA - HBF TERT88 [nTPM]":"27.6","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"7.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"46.7","Cell RNA - Hep G2 [nTPM]":"41.1","Cell RNA - HHSteC [nTPM]":"51.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"4.8","Cell RNA - hTCEpi [nTPM]":"38.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.7","Cell RNA - hTERT-HME1 [nTPM]":"95.6","Cell RNA - hTERT-RPE1 [nTPM]":"125.0","Cell RNA - HUVEC TERT2 [nTPM]":"86.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"51.6","Cell RNA - MCF7 [nTPM]":"24.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"20.0","Cell RNA - OE19 [nTPM]":"57.2","Cell RNA - PC-3 [nTPM]":"229.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"37.6","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"85.1","Cell RNA - RT4 [nTPM]":"39.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"6.4","Cell RNA - SiHa [nTPM]":"87.8","Cell RNA - SK-BR-3 [nTPM]":"21.2","Cell RNA - SK-MEL-30 [nTPM]":"6.1","Cell RNA - SuSa [nTPM]":"21.3","Cell RNA - T-47d [nTPM]":"3.0","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"108.1","Cell RNA - U-138 MG [nTPM]":"28.5","Cell RNA - U-2 OS [nTPM]":"76.7","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"242.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"22.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"258.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"9.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"3.1","Single Cell Type RNA - Adipocytes [nTPM]":"17.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.4","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"202.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"114.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"110.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"66.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"113.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.7","Single Cell Type RNA - dendritic cells [nTPM]":"8.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"96.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"33.8","Single Cell Type RNA - Early spermatids [nTPM]":"5.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"104.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.2","Single Cell Type RNA - Endothelial cells [nTPM]":"26.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"68.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"182.9","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.3","Single Cell Type RNA - Hepatocytes [nTPM]":"23.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"42.0","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"17.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"3.7","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"104.6","Single Cell Type RNA - Paneth cells [nTPM]":"111.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"60.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"89.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"156.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"248.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"42.9","Single Cell Type RNA - Urothelial cells [nTPM]":"200.4"},{"Gene":"EPM2A","Gene synonym":["LD","LDE"],"Ensembl":"ENSG00000112425","Gene description":"EPM2A glucan phosphatase, laforin","Uniprot":["O95278"],"Chromosome":"6","Position":"145382535-145736023","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Carbohydrate metabolism","Glycogen metabolism"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Disease variant","Epilepsy","Glycogen storage disease","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"76.8","tongue":"79.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"66.9","Early spermatids":"33.0","Excitatory neurons":"30.4","Inhibitory neurons":"50.7","Oligodendrocyte precursor cells":"56.8","Oligodendrocytes":"60.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"23.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053643","HPA055468"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053643":"AB_2797247","HPA055468":"AB_2797252"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"11.4","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"11.7","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"3.2","Tissue RNA - cerebellum [nTPM]":"11.9","Tissue RNA - cerebral cortex [nTPM]":"17.8","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"7.3","Tissue RNA - colon [nTPM]":"17.2","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"24.4","Tissue RNA - hippocampal formation [nTPM]":"11.6","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"8.5","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"3.0","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"11.9","Tissue RNA - midbrain [nTPM]":"11.5","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"2.4","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"11.1","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"12.1","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"76.8","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"11.5","Tissue RNA - thymus [nTPM]":"4.8","Tissue RNA - thyroid gland [nTPM]":"3.9","Tissue RNA - tongue [nTPM]":"79.5","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"6.6","Cell RNA - ASC diff [nTPM]":"8.6","Cell RNA - ASC TERT1 [nTPM]":"2.3","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.5","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"23.2","Cell RNA - EFO-21 [nTPM]":"2.7","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"1.8","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"2.6","Cell RNA - HDLM-2 [nTPM]":"9.3","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"2.7","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"12.7","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"7.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.7","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"3.8","Cell RNA - HUVEC TERT2 [nTPM]":"2.0","Cell RNA - JURKAT [nTPM]":"5.0","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"5.4","Cell RNA - LHCN-M2 [nTPM]":"3.8","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"8.4","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"3.2","Cell RNA - PC-3 [nTPM]":"1.9","Cell RNA - REH [nTPM]":"4.8","Cell RNA - RH-30 [nTPM]":"3.1","Cell RNA - RPMI-8226 [nTPM]":"6.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.5","Cell RNA - RT4 [nTPM]":"1.8","Cell RNA - SCLC-21H [nTPM]":"6.3","Cell RNA - SH-SY5Y [nTPM]":"6.4","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"3.3","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"7.3","Cell RNA - TIME [nTPM]":"4.6","Cell RNA - U-138 MG [nTPM]":"2.9","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"2.7","Cell RNA - U-251 MG [nTPM]":"2.6","Cell RNA - U-266\/70 [nTPM]":"4.1","Cell RNA - U-266\/84 [nTPM]":"4.6","Cell RNA - U-698 [nTPM]":"8.6","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"2.8","Cell RNA - WM-115 [nTPM]":"4.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"11.4","Brain RNA - basal ganglia [nTPM]":"11.7","Brain RNA - cerebellum [nTPM]":"11.9","Brain RNA - cerebral cortex [nTPM]":"17.8","Brain RNA - hippocampal formation [nTPM]":"11.6","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"11.9","Brain RNA - midbrain [nTPM]":"11.5","Brain RNA - pons [nTPM]":"11.1","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"11.5","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"66.9","Single Cell Type RNA - B-cells [nTPM]":"4.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"33.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.6","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"6.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"19.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"3.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"1.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.9","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"56.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"60.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"EPO","Gene synonym":["EP"],"Ensembl":"ENSG00000130427","Gene description":"Erythropoietin","Uniprot":["P01588"],"Chromosome":"7","Position":"100720468-100723700","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Erythrocyte maturation"],"Molecular function":["Hormone"],"Disease involvement":["Cancer-related genes","Congenital erythrocytosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"47.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"2.9","Exocrine glandular cells":"4.2","Extravillous trophoblasts":"14.0","Hepatocytes":"19.5","Pancreatic endocrine cells":"3.7","Syncytiotrophoblasts":"2.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"2.7","renal cancer":"5.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"BEWO":"1.6","Hep G2":"6.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010336"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":12300,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010336":"AB_2098408"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.67e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.18e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"3.1","Tissue RNA - liver [nTPM]":"47.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"6.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"19.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"EPS8","Gene synonym":[],"Ensembl":"ENSG00000151491","Gene description":"Epidermal growth factor receptor pathway substrate 8","Uniprot":["Q12929"],"Chromosome":"12","Position":"15620134-15882329","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"317.0","Sertoli cells":"401.0","Smooth muscle cells":"313.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"22.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"253.0","HHSteC":"218.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003897"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA003897":"AB_1848224"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-7"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.11e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"62.3","Tissue RNA - adrenal gland [nTPM]":"13.0","Tissue RNA - amygdala [nTPM]":"12.9","Tissue RNA - appendix [nTPM]":"16.1","Tissue RNA - basal ganglia [nTPM]":"17.4","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"33.7","Tissue RNA - cerebellum [nTPM]":"15.3","Tissue RNA - cerebral cortex [nTPM]":"14.0","Tissue RNA - cervix [nTPM]":"53.9","Tissue RNA - choroid plexus [nTPM]":"14.1","Tissue RNA - colon [nTPM]":"49.7","Tissue RNA - duodenum [nTPM]":"37.6","Tissue RNA - endometrium 1 [nTPM]":"46.2","Tissue RNA - epididymis [nTPM]":"47.1","Tissue RNA - esophagus [nTPM]":"20.5","Tissue RNA - fallopian tube [nTPM]":"20.1","Tissue RNA - gallbladder [nTPM]":"56.0","Tissue RNA - heart muscle [nTPM]":"26.4","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"17.2","Tissue RNA - kidney [nTPM]":"55.8","Tissue RNA - liver [nTPM]":"37.8","Tissue RNA - lung [nTPM]":"29.0","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"18.5","Tissue RNA - midbrain [nTPM]":"20.1","Tissue RNA - ovary [nTPM]":"49.2","Tissue RNA - pancreas [nTPM]":"15.1","Tissue RNA - parathyroid gland [nTPM]":"21.6","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"53.1","Tissue RNA - pons [nTPM]":"19.7","Tissue RNA - prostate [nTPM]":"16.4","Tissue RNA - rectum [nTPM]":"53.7","Tissue RNA - retina [nTPM]":"39.8","Tissue RNA - salivary gland [nTPM]":"13.4","Tissue RNA - seminal vesicle [nTPM]":"39.8","Tissue RNA - skeletal muscle [nTPM]":"13.8","Tissue RNA - skin 1 [nTPM]":"11.9","Tissue RNA - small intestine [nTPM]":"42.7","Tissue RNA - smooth muscle [nTPM]":"53.7","Tissue RNA - spinal cord [nTPM]":"15.5","Tissue RNA - spleen [nTPM]":"11.9","Tissue RNA - stomach 1 [nTPM]":"32.0","Tissue RNA - testis [nTPM]":"15.6","Tissue RNA - thalamus [nTPM]":"16.1","Tissue RNA - thymus [nTPM]":"4.8","Tissue RNA - thyroid gland [nTPM]":"22.8","Tissue RNA - tongue [nTPM]":"24.3","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"51.7","Tissue RNA - vagina [nTPM]":"21.4","Tissue RNA - white matter [nTPM]":"20.8","Cell RNA - A-431 [nTPM]":"65.0","Cell RNA - A549 [nTPM]":"38.8","Cell RNA - AF22 [nTPM]":"37.7","Cell RNA - AN3-CA [nTPM]":"1.4","Cell RNA - ASC diff [nTPM]":"253.0","Cell RNA - ASC TERT1 [nTPM]":"177.6","Cell RNA - BEWO [nTPM]":"53.1","Cell RNA - BJ [nTPM]":"73.6","Cell RNA - BJ hTERT+ [nTPM]":"59.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"46.1","Cell RNA - CACO-2 [nTPM]":"33.3","Cell RNA - CAPAN-2 [nTPM]":"97.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.4","Cell RNA - fHDF\/TERT166 [nTPM]":"140.4","Cell RNA - GAMG [nTPM]":"114.4","Cell RNA - HaCaT [nTPM]":"16.4","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"9.5","Cell RNA - HBF TERT88 [nTPM]":"52.4","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"12.6","Cell RNA - HEL [nTPM]":"5.7","Cell RNA - HeLa [nTPM]":"11.2","Cell RNA - Hep G2 [nTPM]":"34.7","Cell RNA - HHSteC [nTPM]":"218.1","Cell RNA - HL-60 [nTPM]":"4.4","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"159.8","Cell RNA - hTCEpi [nTPM]":"42.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"91.7","Cell RNA - hTERT-HME1 [nTPM]":"115.7","Cell RNA - hTERT-RPE1 [nTPM]":"44.6","Cell RNA - HUVEC TERT2 [nTPM]":"17.7","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"169.0","Cell RNA - MCF7 [nTPM]":"17.5","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"2.8","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"50.3","Cell RNA - PC-3 [nTPM]":"30.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"109.5","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"97.7","Cell RNA - RT4 [nTPM]":"92.5","Cell RNA - SCLC-21H [nTPM]":"3.1","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"21.4","Cell RNA - SK-BR-3 [nTPM]":"12.4","Cell RNA - SK-MEL-30 [nTPM]":"91.5","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"34.2","Cell RNA - THP-1 [nTPM]":"4.3","Cell RNA - TIME [nTPM]":"28.7","Cell RNA - U-138 MG [nTPM]":"54.7","Cell RNA - U-2 OS [nTPM]":"14.3","Cell RNA - U-2197 [nTPM]":"32.4","Cell RNA - U-251 MG [nTPM]":"30.7","Cell RNA - U-266\/70 [nTPM]":"3.6","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"32.1","Cell RNA - U-937 [nTPM]":"10.7","Cell RNA - WM-115 [nTPM]":"160.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"10.8","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"5.5","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"4.4","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"22.2","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"12.9","Brain RNA - basal ganglia [nTPM]":"17.4","Brain RNA - cerebellum [nTPM]":"15.3","Brain RNA - cerebral cortex [nTPM]":"14.0","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"17.2","Brain RNA - medulla oblongata [nTPM]":"18.5","Brain RNA - midbrain [nTPM]":"20.1","Brain RNA - pons [nTPM]":"19.7","Brain RNA - spinal cord [nTPM]":"15.5","Brain RNA - thalamus [nTPM]":"16.1","Brain RNA - white matter [nTPM]":"20.8","Single Cell Type RNA - Adipocytes [nTPM]":"121.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"175.9","Single Cell Type RNA - Astrocytes [nTPM]":"91.1","Single Cell Type RNA - B-cells [nTPM]":"11.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"39.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"9.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"87.2","Single Cell Type RNA - Club cells [nTPM]":"58.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.0","Single Cell Type RNA - dendritic cells [nTPM]":"15.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"317.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"69.4","Single Cell Type RNA - Early spermatids [nTPM]":"67.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"87.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"72.0","Single Cell Type RNA - Endothelial cells [nTPM]":"61.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"38.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"68.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"73.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"81.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"152.2","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"139.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.0","Single Cell Type RNA - Hepatocytes [nTPM]":"36.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"65.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.5","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"54.1","Single Cell Type RNA - Langerhans cells [nTPM]":"35.6","Single Cell Type RNA - Late spermatids [nTPM]":"49.4","Single Cell Type RNA - Leydig cells [nTPM]":"134.8","Single Cell Type RNA - Macrophages [nTPM]":"46.2","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"148.0","Single Cell Type RNA - monocytes [nTPM]":"8.6","Single Cell Type RNA - Muller glia cells [nTPM]":"15.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"121.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"96.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"97.0","Single Cell Type RNA - Paneth cells [nTPM]":"217.8","Single Cell Type RNA - Peritubular cells [nTPM]":"43.6","Single Cell Type RNA - Plasma cells [nTPM]":"5.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"69.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"114.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"104.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"153.7","Single Cell Type RNA - Sertoli cells [nTPM]":"401.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"313.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.9","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - T-cells [nTPM]":"11.8","Single Cell Type RNA - Theca cells [nTPM]":"40.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"80.0","Single Cell Type RNA - Urothelial cells [nTPM]":"97.6"},{"Gene":"EPS8L2","Gene synonym":["FLJ21935","FLJ22171","MGC3088"],"Ensembl":"ENSG00000177106","Gene description":"EPS8 like 2","Uniprot":["Q9H6S3"],"Chromosome":"11","Position":"694438-727727","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"188.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"211.4","Paneth cells":"175.3","Proximal enterocytes":"235.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"plasmacytoid DC":"3.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"3.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"234.3","BEWO":"220.8","CAPAN-2":"206.6","SK-BR-3":"257.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"10","RNA pig brain regional specific nTPM":{"cerebellum":"9.2"},"Antibody":["HPA041143"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041143":"AB_10794985"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.31e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.8","Tissue RNA - adrenal gland [nTPM]":"11.2","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"27.0","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"5.5","Tissue RNA - cervix [nTPM]":"49.4","Tissue RNA - choroid plexus [nTPM]":"4.9","Tissue RNA - colon [nTPM]":"42.7","Tissue RNA - duodenum [nTPM]":"100.8","Tissue RNA - endometrium 1 [nTPM]":"11.4","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"188.5","Tissue RNA - fallopian tube [nTPM]":"19.2","Tissue RNA - gallbladder [nTPM]":"13.3","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"6.8","Tissue RNA - kidney [nTPM]":"98.4","Tissue RNA - liver [nTPM]":"101.7","Tissue RNA - lung [nTPM]":"32.4","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"10.9","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"11.8","Tissue RNA - pancreas [nTPM]":"43.7","Tissue RNA - parathyroid gland [nTPM]":"3.8","Tissue RNA - pituitary gland [nTPM]":"11.5","Tissue RNA - placenta [nTPM]":"17.7","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"29.3","Tissue RNA - rectum [nTPM]":"15.5","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"94.6","Tissue RNA - seminal vesicle [nTPM]":"15.2","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"76.3","Tissue RNA - small intestine [nTPM]":"105.0","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"48.1","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"70.2","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"10.9","Tissue RNA - urinary bladder [nTPM]":"17.5","Tissue RNA - vagina [nTPM]":"80.1","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"234.3","Cell RNA - A549 [nTPM]":"68.6","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"1.6","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"14.4","Cell RNA - BEWO [nTPM]":"220.8","Cell RNA - BJ [nTPM]":"20.1","Cell RNA - BJ hTERT+ [nTPM]":"20.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.5","Cell RNA - CACO-2 [nTPM]":"51.4","Cell RNA - CAPAN-2 [nTPM]":"206.6","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"81.6","Cell RNA - fHDF\/TERT166 [nTPM]":"21.4","Cell RNA - GAMG [nTPM]":"5.4","Cell RNA - HaCaT [nTPM]":"122.4","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"117.8","Cell RNA - HBF TERT88 [nTPM]":"6.4","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"27.7","Cell RNA - Hep G2 [nTPM]":"94.7","Cell RNA - HHSteC [nTPM]":"16.3","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"77.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.0","Cell RNA - hTERT-HME1 [nTPM]":"18.7","Cell RNA - hTERT-RPE1 [nTPM]":"12.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"72.1","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"2.7","Cell RNA - OE19 [nTPM]":"71.5","Cell RNA - PC-3 [nTPM]":"24.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"103.8","Cell RNA - RT4 [nTPM]":"55.2","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"75.9","Cell RNA - SK-BR-3 [nTPM]":"257.5","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"14.3","Cell RNA - T-47d [nTPM]":"94.9","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"1.5","Cell RNA - U-138 MG [nTPM]":"11.2","Cell RNA - U-2 OS [nTPM]":"27.3","Cell RNA - U-2197 [nTPM]":"7.2","Cell RNA - U-251 MG [nTPM]":"1.6","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"6.1","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"5.5","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"6.8","Brain RNA - medulla oblongata [nTPM]":"10.9","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"141.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.8","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"11.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"62.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"90.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.9","Single Cell Type RNA - dendritic cells [nTPM]":"21.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"211.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"55.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"80.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.4","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"131.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.8","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"59.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"76.8","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"2.1","Single Cell Type RNA - Langerhans cells [nTPM]":"7.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"10.0","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"83.2","Single Cell Type RNA - Paneth cells [nTPM]":"175.3","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"7.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"235.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"108.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"60.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"74.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"92.5","Single Cell Type RNA - T-cells [nTPM]":"18.6","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"77.2","Single Cell Type RNA - Urothelial cells [nTPM]":"32.1"},{"Gene":"ERBB4","Gene synonym":["ALS19","HER4"],"Ensembl":"ENSG00000178568","Gene description":"Erb-b2 receptor tyrosine kinase 4","Uniprot":["Q15303"],"Chromosome":"2","Position":"211375717-212538841","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Lactation","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Amyotrophic lateral sclerosis","Cancer-related genes","Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"16.9","fallopian tube":"11.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2020.2","Inhibitory neurons":"6091.7","Oligodendrocyte precursor cells":"2369.0","Oligodendrocytes":"1049.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"4.1","endometrial cancer":"2.1","glioma":"1.2","ovarian cancer":"2.8","testis cancer":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"6.9","EFO-21":"5.1","HEK 293":"3.8","RPTEC TERT1":"5.6","SCLC-21H":"3.1","T-47d":"5.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000276","HPA012016","CAB025522"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000276":null,"CAB025522":null,"HPA012016":"AB_1846541"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"10.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"13.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"5.6","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"11.5","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"11.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"9.9","Tissue RNA - hypothalamus [nTPM]":"12.7","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"16.9","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"6.9","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"5.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"3.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.6","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"3.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"5.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"10.0","Brain RNA - basal ganglia [nTPM]":"13.3","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"11.5","Brain RNA - hippocampal formation [nTPM]":"9.9","Brain RNA - hypothalamus [nTPM]":"12.7","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"16.9","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"2020.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"10.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"6.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"62.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6091.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"96.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2369.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1049.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"ERCC6","Gene synonym":["ARMD5","CKN2","CSB","RAD26"],"Ensembl":"ENSG00000225830","Gene description":"ERCC excision repair 6, chromatin remodeling factor","Uniprot":["P0DP91","Q03468"],"Chromosome":"10","Position":"49454168-49539538","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Age-related macular degeneration","Cancer-related genes","Cataract","Cockayne syndrome","Deafness","Disease variant","Dwarfism","Mental retardation","Premature ovarian failure","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"53.8","hTERT-RPE1":"123.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071297"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA071297":"AB_2732177"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.7","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"3.8","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"3.0","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"2.7","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"3.2","Tissue RNA - liver [nTPM]":"3.3","Tissue RNA - lung [nTPM]":"2.7","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"2.1","Tissue RNA - prostate [nTPM]":"3.3","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"2.9","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"3.1","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"11.2","Cell RNA - A549 [nTPM]":"5.5","Cell RNA - AF22 [nTPM]":"4.1","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"6.6","Cell RNA - ASC TERT1 [nTPM]":"10.5","Cell RNA - BEWO [nTPM]":"3.4","Cell RNA - BJ [nTPM]":"21.2","Cell RNA - BJ hTERT+ [nTPM]":"27.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.9","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"5.6","Cell RNA - Daudi [nTPM]":"4.9","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"18.7","Cell RNA - GAMG [nTPM]":"6.7","Cell RNA - HaCaT [nTPM]":"9.5","Cell RNA - HAP1 [nTPM]":"6.3","Cell RNA - HBEC3-KT [nTPM]":"16.6","Cell RNA - HBF TERT88 [nTPM]":"13.5","Cell RNA - HDLM-2 [nTPM]":"8.4","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"3.9","Cell RNA - HeLa [nTPM]":"21.7","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"3.9","Cell RNA - HL-60 [nTPM]":"5.0","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"4.3","Cell RNA - hTCEpi [nTPM]":"17.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.9","Cell RNA - hTERT-HME1 [nTPM]":"53.8","Cell RNA - hTERT-RPE1 [nTPM]":"123.4","Cell RNA - HUVEC TERT2 [nTPM]":"19.8","Cell RNA - JURKAT [nTPM]":"2.9","Cell RNA - K-562 [nTPM]":"6.8","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"16.8","Cell RNA - MCF7 [nTPM]":"8.3","Cell RNA - MOLT-4 [nTPM]":"3.4","Cell RNA - NB-4 [nTPM]":"2.0","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"3.5","Cell RNA - PC-3 [nTPM]":"10.2","Cell RNA - REH [nTPM]":"2.3","Cell RNA - RH-30 [nTPM]":"5.8","Cell RNA - RPMI-8226 [nTPM]":"2.6","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"7.1","Cell RNA - SCLC-21H [nTPM]":"5.9","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"15.4","Cell RNA - SK-BR-3 [nTPM]":"3.6","Cell RNA - SK-MEL-30 [nTPM]":"8.2","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"7.1","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"38.9","Cell RNA - U-138 MG [nTPM]":"7.0","Cell RNA - U-2 OS [nTPM]":"5.5","Cell RNA - U-2197 [nTPM]":"8.6","Cell RNA - U-251 MG [nTPM]":"5.2","Cell RNA - U-266\/70 [nTPM]":"3.3","Cell RNA - U-266\/84 [nTPM]":"4.5","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"7.3","Cell RNA - U-937 [nTPM]":"5.0","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"13.1","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"7.5","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"6.8","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"3.9","Blood RNA - naive B-cell [nTPM]":"5.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"7.2","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"5.3","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.1","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.2","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"6.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - dendritic cells [nTPM]":"10.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.7","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.1","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"8.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"4.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"15.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"11.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"3.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.3","Single Cell Type RNA - Spermatogonia [nTPM]":"5.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"7.4","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"ERCC8","Gene synonym":["CKN1","CSA"],"Ensembl":"ENSG00000049167","Gene description":"ERCC excision repair 8, CSA ubiquitin ligase complex subunit","Uniprot":["Q13216"],"Chromosome":"5","Position":"60866454-60945073","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cockayne syndrome","Deafness","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"47.3","Excitatory neurons":"51.8","Inhibitory neurons":"47.9","Oligodendrocyte precursor cells":"44.2","Oligodendrocytes":"57.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029328"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029328":"AB_2673000"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"3.2","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"3.0","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"3.2","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"4.0","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"2.2","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"2.7","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"2.1","Tissue RNA - prostate [nTPM]":"2.2","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"2.1","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"2.2","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"2.9","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"2.5","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"4.8","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"7.3","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"4.2","Cell RNA - BEWO [nTPM]":"8.2","Cell RNA - BJ [nTPM]":"7.6","Cell RNA - BJ hTERT+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.2","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"8.6","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"9.4","Cell RNA - fHDF\/TERT166 [nTPM]":"4.2","Cell RNA - GAMG [nTPM]":"14.4","Cell RNA - HaCaT [nTPM]":"4.0","Cell RNA - HAP1 [nTPM]":"10.6","Cell RNA - HBEC3-KT [nTPM]":"7.4","Cell RNA - HBF TERT88 [nTPM]":"11.1","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"6.0","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"7.3","Cell RNA - Hep G2 [nTPM]":"7.7","Cell RNA - HHSteC [nTPM]":"5.0","Cell RNA - HL-60 [nTPM]":"4.9","Cell RNA - HMC-1 [nTPM]":"4.5","Cell RNA - HSkMC [nTPM]":"6.5","Cell RNA - hTCEpi [nTPM]":"6.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.1","Cell RNA - hTERT-HME1 [nTPM]":"7.5","Cell RNA - hTERT-RPE1 [nTPM]":"3.3","Cell RNA - HUVEC TERT2 [nTPM]":"9.9","Cell RNA - JURKAT [nTPM]":"8.8","Cell RNA - K-562 [nTPM]":"8.0","Cell RNA - Karpas-707 [nTPM]":"4.2","Cell RNA - LHCN-M2 [nTPM]":"5.2","Cell RNA - MCF7 [nTPM]":"8.1","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"8.0","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"2.8","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"9.6","Cell RNA - RPMI-8226 [nTPM]":"9.1","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"5.9","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"11.3","Cell RNA - SiHa [nTPM]":"8.6","Cell RNA - SK-BR-3 [nTPM]":"3.6","Cell RNA - SK-MEL-30 [nTPM]":"6.5","Cell RNA - SuSa [nTPM]":"7.6","Cell RNA - T-47d [nTPM]":"11.2","Cell RNA - THP-1 [nTPM]":"3.6","Cell RNA - TIME [nTPM]":"3.8","Cell RNA - U-138 MG [nTPM]":"3.8","Cell RNA - U-2 OS [nTPM]":"7.4","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"11.9","Cell RNA - U-698 [nTPM]":"12.7","Cell RNA - U-87 MG [nTPM]":"5.9","Cell RNA - U-937 [nTPM]":"10.1","Cell RNA - WM-115 [nTPM]":"8.3","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"4.2","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"7.1","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"3.2","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.1","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"3.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"28.4","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"3.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"4.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"5.0","Single Cell Type RNA - Early spermatids [nTPM]":"47.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.1","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.1","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"11.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"7.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"44.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"57.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.2","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"11.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.6","Single Cell Type RNA - Spermatocytes [nTPM]":"22.5","Single Cell Type RNA - Spermatogonia [nTPM]":"9.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"8.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"3.5"},{"Gene":"ERLIN1","Gene synonym":["C10orf69","Erlin-1","KE04","SPFH1","SPG62"],"Ensembl":"ENSG00000107566","Gene description":"ER lipid raft associated 1","Uniprot":["O75477"],"Chromosome":"10","Position":"100150094-100186033","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"114.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"77.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011252"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA011252":"AB_1853965"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.63e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Tissue RNA - adipose tissue [nTPM]":"29.4","Tissue RNA - adrenal gland [nTPM]":"14.2","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"21.4","Tissue RNA - basal ganglia [nTPM]":"10.5","Tissue RNA - bone marrow [nTPM]":"76.2","Tissue RNA - breast [nTPM]":"21.4","Tissue RNA - cerebellum [nTPM]":"9.5","Tissue RNA - cerebral cortex [nTPM]":"10.1","Tissue RNA - cervix [nTPM]":"27.5","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"37.0","Tissue RNA - duodenum [nTPM]":"40.4","Tissue RNA - endometrium 1 [nTPM]":"21.8","Tissue RNA - epididymis [nTPM]":"17.6","Tissue RNA - esophagus [nTPM]":"32.8","Tissue RNA - fallopian tube [nTPM]":"31.6","Tissue RNA - gallbladder [nTPM]":"16.3","Tissue RNA - heart muscle [nTPM]":"11.0","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"9.4","Tissue RNA - kidney [nTPM]":"27.2","Tissue RNA - liver [nTPM]":"114.1","Tissue RNA - lung [nTPM]":"19.1","Tissue RNA - lymph node [nTPM]":"14.5","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"30.4","Tissue RNA - pancreas [nTPM]":"19.2","Tissue RNA - parathyroid gland [nTPM]":"19.4","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"42.2","Tissue RNA - pons [nTPM]":"9.0","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"38.2","Tissue RNA - retina [nTPM]":"10.8","Tissue RNA - salivary gland [nTPM]":"15.1","Tissue RNA - seminal vesicle [nTPM]":"16.4","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"22.5","Tissue RNA - small intestine [nTPM]":"30.2","Tissue RNA - smooth muscle [nTPM]":"22.4","Tissue RNA - spinal cord [nTPM]":"8.8","Tissue RNA - spleen [nTPM]":"16.6","Tissue RNA - stomach 1 [nTPM]":"36.8","Tissue RNA - testis [nTPM]":"28.0","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"15.6","Tissue RNA - thyroid gland [nTPM]":"26.2","Tissue RNA - tongue [nTPM]":"13.6","Tissue RNA - tonsil [nTPM]":"21.2","Tissue RNA - urinary bladder [nTPM]":"28.6","Tissue RNA - vagina [nTPM]":"19.1","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"97.4","Cell RNA - A549 [nTPM]":"95.3","Cell RNA - AF22 [nTPM]":"46.9","Cell RNA - AN3-CA [nTPM]":"86.3","Cell RNA - ASC diff [nTPM]":"113.5","Cell RNA - ASC TERT1 [nTPM]":"107.9","Cell RNA - BEWO [nTPM]":"96.8","Cell RNA - BJ [nTPM]":"148.7","Cell RNA - BJ hTERT+ [nTPM]":"138.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"120.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"137.5","Cell RNA - CACO-2 [nTPM]":"64.0","Cell RNA - CAPAN-2 [nTPM]":"109.9","Cell RNA - Daudi [nTPM]":"42.6","Cell RNA - EFO-21 [nTPM]":"59.7","Cell RNA - fHDF\/TERT166 [nTPM]":"139.9","Cell RNA - GAMG [nTPM]":"100.5","Cell RNA - HaCaT [nTPM]":"98.5","Cell RNA - HAP1 [nTPM]":"42.6","Cell RNA - HBEC3-KT [nTPM]":"90.0","Cell RNA - HBF TERT88 [nTPM]":"164.1","Cell RNA - HDLM-2 [nTPM]":"26.1","Cell RNA - HEK 293 [nTPM]":"38.8","Cell RNA - HEL [nTPM]":"36.7","Cell RNA - HeLa [nTPM]":"38.5","Cell RNA - Hep G2 [nTPM]":"83.5","Cell RNA - HHSteC [nTPM]":"47.6","Cell RNA - HL-60 [nTPM]":"128.4","Cell RNA - HMC-1 [nTPM]":"39.4","Cell RNA - HSkMC [nTPM]":"62.6","Cell RNA - hTCEpi [nTPM]":"53.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"105.8","Cell RNA - hTERT-HME1 [nTPM]":"129.2","Cell RNA - hTERT-RPE1 [nTPM]":"114.9","Cell RNA - HUVEC TERT2 [nTPM]":"90.1","Cell RNA - JURKAT [nTPM]":"43.5","Cell RNA - K-562 [nTPM]":"36.8","Cell RNA - Karpas-707 [nTPM]":"25.2","Cell RNA - LHCN-M2 [nTPM]":"130.2","Cell RNA - MCF7 [nTPM]":"40.7","Cell RNA - MOLT-4 [nTPM]":"33.5","Cell RNA - NB-4 [nTPM]":"65.9","Cell RNA - NTERA-2 [nTPM]":"33.8","Cell RNA - OE19 [nTPM]":"66.2","Cell RNA - PC-3 [nTPM]":"40.4","Cell RNA - REH [nTPM]":"28.3","Cell RNA - RH-30 [nTPM]":"77.2","Cell RNA - RPMI-8226 [nTPM]":"31.6","Cell RNA - RPTEC TERT1 [nTPM]":"53.9","Cell RNA - RT4 [nTPM]":"37.6","Cell RNA - SCLC-21H [nTPM]":"19.1","Cell RNA - SH-SY5Y [nTPM]":"31.1","Cell RNA - SiHa [nTPM]":"85.6","Cell RNA - SK-BR-3 [nTPM]":"23.6","Cell RNA - SK-MEL-30 [nTPM]":"56.0","Cell RNA - SuSa [nTPM]":"53.8","Cell RNA - T-47d [nTPM]":"59.3","Cell RNA - THP-1 [nTPM]":"109.0","Cell RNA - TIME [nTPM]":"101.7","Cell RNA - U-138 MG [nTPM]":"118.7","Cell RNA - U-2 OS [nTPM]":"92.4","Cell RNA - U-2197 [nTPM]":"72.4","Cell RNA - U-251 MG [nTPM]":"160.8","Cell RNA - U-266\/70 [nTPM]":"19.6","Cell RNA - U-266\/84 [nTPM]":"35.2","Cell RNA - U-698 [nTPM]":"57.1","Cell RNA - U-87 MG [nTPM]":"105.6","Cell RNA - U-937 [nTPM]":"204.8","Cell RNA - WM-115 [nTPM]":"60.6","Blood RNA - basophil [nTPM]":"8.1","Blood RNA - classical monocyte [nTPM]":"20.4","Blood RNA - eosinophil [nTPM]":"24.4","Blood RNA - gdT-cell [nTPM]":"10.5","Blood RNA - intermediate monocyte [nTPM]":"15.1","Blood RNA - MAIT T-cell [nTPM]":"9.3","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"7.9","Blood RNA - memory CD8 T-cell [nTPM]":"8.6","Blood RNA - myeloid DC [nTPM]":"16.3","Blood RNA - naive B-cell [nTPM]":"6.7","Blood RNA - naive CD4 T-cell [nTPM]":"8.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.9","Blood RNA - neutrophil [nTPM]":"15.0","Blood RNA - NK-cell [nTPM]":"9.9","Blood RNA - non-classical monocyte [nTPM]":"11.9","Blood RNA - plasmacytoid DC [nTPM]":"4.1","Blood RNA - T-reg [nTPM]":"5.6","Blood RNA - total PBMC [nTPM]":"9.7","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"10.5","Brain RNA - cerebellum [nTPM]":"9.5","Brain RNA - cerebral cortex [nTPM]":"10.1","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"9.4","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"9.0","Brain RNA - spinal cord [nTPM]":"8.8","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"28.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"6.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"4.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"14.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.6","Single Cell Type RNA - dendritic cells [nTPM]":"6.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"28.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.7","Single Cell Type RNA - Fibroblasts [nTPM]":"17.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.9","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"19.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"77.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.3","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.4","Single Cell Type RNA - Langerhans cells [nTPM]":"7.2","Single Cell Type RNA - Late spermatids [nTPM]":"12.9","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"12.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"13.3","Single Cell Type RNA - Muller glia cells [nTPM]":"5.9","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"19.8","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"4.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.8","Single Cell Type RNA - Spermatocytes [nTPM]":"50.9","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.8","Single Cell Type RNA - T-cells [nTPM]":"6.6","Single Cell Type RNA - Theca cells [nTPM]":"19.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.6","Single Cell Type RNA - Urothelial cells [nTPM]":"15.6"},{"Gene":"ERLIN2","Gene synonym":["C8orf2","Erlin-2","NET32","SPFH2","SPG18"],"Ensembl":"ENSG00000147475","Gene description":"ER lipid raft associated 2","Uniprot":["O94905"],"Chromosome":"8","Position":"37736601-37758422","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002025","CAB014894"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB014894":null,"HPA002025":"AB_1080077"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.16e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.51e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.67e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Tissue RNA - adipose tissue [nTPM]":"20.3","Tissue RNA - adrenal gland [nTPM]":"17.8","Tissue RNA - amygdala [nTPM]":"15.7","Tissue RNA - appendix [nTPM]":"14.6","Tissue RNA - basal ganglia [nTPM]":"17.3","Tissue RNA - bone marrow [nTPM]":"14.4","Tissue RNA - breast [nTPM]":"25.0","Tissue RNA - cerebellum [nTPM]":"16.5","Tissue RNA - cerebral cortex [nTPM]":"16.8","Tissue RNA - cervix [nTPM]":"20.0","Tissue RNA - choroid plexus [nTPM]":"27.2","Tissue RNA - colon [nTPM]":"24.2","Tissue RNA - duodenum [nTPM]":"17.7","Tissue RNA - endometrium 1 [nTPM]":"21.2","Tissue RNA - epididymis [nTPM]":"32.3","Tissue RNA - esophagus [nTPM]":"17.9","Tissue RNA - fallopian tube [nTPM]":"30.1","Tissue RNA - gallbladder [nTPM]":"19.8","Tissue RNA - heart muscle [nTPM]":"17.8","Tissue RNA - hippocampal formation [nTPM]":"14.2","Tissue RNA - hypothalamus [nTPM]":"16.3","Tissue RNA - kidney [nTPM]":"40.4","Tissue RNA - liver [nTPM]":"40.8","Tissue RNA - lung [nTPM]":"15.5","Tissue RNA - lymph node [nTPM]":"11.5","Tissue RNA - medulla oblongata [nTPM]":"18.0","Tissue RNA - midbrain [nTPM]":"18.5","Tissue RNA - ovary [nTPM]":"30.8","Tissue RNA - pancreas [nTPM]":"26.2","Tissue RNA - parathyroid gland [nTPM]":"41.4","Tissue RNA - pituitary gland [nTPM]":"8.3","Tissue RNA - placenta [nTPM]":"21.2","Tissue RNA - pons [nTPM]":"17.7","Tissue RNA - prostate [nTPM]":"25.4","Tissue RNA - rectum [nTPM]":"25.0","Tissue RNA - retina [nTPM]":"21.6","Tissue RNA - salivary gland [nTPM]":"29.4","Tissue RNA - seminal vesicle [nTPM]":"23.8","Tissue RNA - skeletal muscle [nTPM]":"18.9","Tissue RNA - skin 1 [nTPM]":"15.3","Tissue RNA - small intestine [nTPM]":"23.6","Tissue RNA - smooth muscle [nTPM]":"19.5","Tissue RNA - spinal cord [nTPM]":"17.9","Tissue RNA - spleen [nTPM]":"14.6","Tissue RNA - stomach 1 [nTPM]":"24.9","Tissue RNA - testis [nTPM]":"17.0","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"14.7","Tissue RNA - thyroid gland [nTPM]":"46.5","Tissue RNA - tongue [nTPM]":"14.1","Tissue RNA - tonsil [nTPM]":"12.6","Tissue RNA - urinary bladder [nTPM]":"16.8","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"18.6","Cell RNA - A-431 [nTPM]":"39.0","Cell RNA - A549 [nTPM]":"38.5","Cell RNA - AF22 [nTPM]":"43.0","Cell RNA - AN3-CA [nTPM]":"31.4","Cell RNA - ASC diff [nTPM]":"47.3","Cell RNA - ASC TERT1 [nTPM]":"33.9","Cell RNA - BEWO [nTPM]":"47.2","Cell RNA - BJ [nTPM]":"59.1","Cell RNA - BJ hTERT+ [nTPM]":"51.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.2","Cell RNA - CACO-2 [nTPM]":"20.1","Cell RNA - CAPAN-2 [nTPM]":"50.8","Cell RNA - Daudi [nTPM]":"18.9","Cell RNA - EFO-21 [nTPM]":"95.8","Cell RNA - fHDF\/TERT166 [nTPM]":"63.4","Cell RNA - GAMG [nTPM]":"30.3","Cell RNA - HaCaT [nTPM]":"41.4","Cell RNA - HAP1 [nTPM]":"31.2","Cell RNA - HBEC3-KT [nTPM]":"48.4","Cell RNA - HBF TERT88 [nTPM]":"46.8","Cell RNA - HDLM-2 [nTPM]":"11.2","Cell RNA - HEK 293 [nTPM]":"24.2","Cell RNA - HEL [nTPM]":"27.8","Cell RNA - HeLa [nTPM]":"22.7","Cell RNA - Hep G2 [nTPM]":"22.7","Cell RNA - HHSteC [nTPM]":"31.5","Cell RNA - HL-60 [nTPM]":"17.8","Cell RNA - HMC-1 [nTPM]":"34.1","Cell RNA - HSkMC [nTPM]":"43.3","Cell RNA - hTCEpi [nTPM]":"49.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.3","Cell RNA - hTERT-HME1 [nTPM]":"48.1","Cell RNA - hTERT-RPE1 [nTPM]":"39.6","Cell RNA - HUVEC TERT2 [nTPM]":"30.7","Cell RNA - JURKAT [nTPM]":"17.2","Cell RNA - K-562 [nTPM]":"51.1","Cell RNA - Karpas-707 [nTPM]":"17.7","Cell RNA - LHCN-M2 [nTPM]":"47.4","Cell RNA - MCF7 [nTPM]":"18.3","Cell RNA - MOLT-4 [nTPM]":"25.8","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"45.9","Cell RNA - OE19 [nTPM]":"53.8","Cell RNA - PC-3 [nTPM]":"17.7","Cell RNA - REH [nTPM]":"17.9","Cell RNA - RH-30 [nTPM]":"29.9","Cell RNA - RPMI-8226 [nTPM]":"15.2","Cell RNA - RPTEC TERT1 [nTPM]":"42.8","Cell RNA - RT4 [nTPM]":"41.9","Cell RNA - SCLC-21H [nTPM]":"7.7","Cell RNA - SH-SY5Y [nTPM]":"20.7","Cell RNA - SiHa [nTPM]":"39.3","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"35.6","Cell RNA - SuSa [nTPM]":"50.1","Cell RNA - T-47d [nTPM]":"62.0","Cell RNA - THP-1 [nTPM]":"27.1","Cell RNA - TIME [nTPM]":"31.1","Cell RNA - U-138 MG [nTPM]":"30.9","Cell RNA - U-2 OS [nTPM]":"26.4","Cell RNA - U-2197 [nTPM]":"56.8","Cell RNA - U-251 MG [nTPM]":"31.1","Cell RNA - U-266\/70 [nTPM]":"24.3","Cell RNA - U-266\/84 [nTPM]":"41.0","Cell RNA - U-698 [nTPM]":"24.2","Cell RNA - U-87 MG [nTPM]":"55.0","Cell RNA - U-937 [nTPM]":"28.4","Cell RNA - WM-115 [nTPM]":"40.7","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"6.5","Blood RNA - eosinophil [nTPM]":"13.4","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"7.0","Blood RNA - MAIT T-cell [nTPM]":"3.6","Blood RNA - memory B-cell [nTPM]":"4.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"5.4","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"6.1","Blood RNA - NK-cell [nTPM]":"2.5","Blood RNA - non-classical monocyte [nTPM]":"9.6","Blood RNA - plasmacytoid DC [nTPM]":"7.6","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"15.7","Brain RNA - basal ganglia [nTPM]":"17.3","Brain RNA - cerebellum [nTPM]":"16.5","Brain RNA - cerebral cortex [nTPM]":"16.8","Brain RNA - hippocampal formation [nTPM]":"14.2","Brain RNA - hypothalamus [nTPM]":"16.3","Brain RNA - medulla oblongata [nTPM]":"18.0","Brain RNA - midbrain [nTPM]":"18.5","Brain RNA - pons [nTPM]":"17.7","Brain RNA - spinal cord [nTPM]":"17.9","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"18.6","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"25.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"22.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"23.8","Single Cell Type RNA - Early spermatids [nTPM]":"21.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.5","Single Cell Type RNA - Endothelial cells [nTPM]":"13.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.0","Single Cell Type RNA - Fibroblasts [nTPM]":"18.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.8","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"14.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"41.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.6","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"23.9","Single Cell Type RNA - Langerhans cells [nTPM]":"6.6","Single Cell Type RNA - Late spermatids [nTPM]":"16.8","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"16.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"12.3","Single Cell Type RNA - Muller glia cells [nTPM]":"23.5","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.8","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"16.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"47.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.8","Single Cell Type RNA - Spermatocytes [nTPM]":"47.4","Single Cell Type RNA - Spermatogonia [nTPM]":"18.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"12.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.8"},{"Gene":"ESPN","Gene synonym":["DFNB36"],"Ensembl":"ENSG00000187017","Gene description":"Espin","Uniprot":["B1AK53"],"Chromosome":"1","Position":"6424776-6461367","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":["Actin-binding"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"129.1","retina":"117.8","testis":"145.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"175.5","Early spermatids":"137.5","Late spermatids":"461.6","Muller glia cells":"272.5","Paneth cells":"186.3","Proximal enterocytes":"512.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"13.4","thalamus":"6.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"48.9","Hep G2":"81.5","SK-BR-3":"160.1","T-47d":"53.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"2.6"},"Antibody":["HPA028674","HPA060220"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA028674":"AB_10601316","HPA060220":"AB_2684224"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"28.0","Tissue RNA - breast [nTPM]":"9.2","Tissue RNA - cerebellum [nTPM]":"13.4","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"30.3","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"28.2","Tissue RNA - duodenum [nTPM]":"90.4","Tissue RNA - endometrium 1 [nTPM]":"2.4","Tissue RNA - epididymis [nTPM]":"39.9","Tissue RNA - esophagus [nTPM]":"34.3","Tissue RNA - fallopian tube [nTPM]":"18.6","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"63.4","Tissue RNA - liver [nTPM]":"129.1","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"26.8","Tissue RNA - pituitary gland [nTPM]":"42.1","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"10.0","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"117.8","Tissue RNA - salivary gland [nTPM]":"9.4","Tissue RNA - seminal vesicle [nTPM]":"6.2","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"91.7","Tissue RNA - small intestine [nTPM]":"89.5","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"2.7","Tissue RNA - testis [nTPM]":"145.3","Tissue RNA - thalamus [nTPM]":"6.1","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"22.3","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"14.1","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"48.9","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"29.9","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"6.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"32.6","Cell RNA - HAP1 [nTPM]":"2.3","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"81.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"2.7","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"17.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"28.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"3.8","Cell RNA - PC-3 [nTPM]":"12.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"10.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"21.0","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"3.7","Cell RNA - SK-BR-3 [nTPM]":"160.1","Cell RNA - SK-MEL-30 [nTPM]":"5.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"53.6","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"15.6","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"2.5","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"13.4","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"6.1","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"5.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"68.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"175.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"137.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"109.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"461.6","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"272.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"186.3","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"512.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"102.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"72.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"12.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"ESRP1","Gene synonym":["FLJ20171","RBM35A"],"Ensembl":"ENSG00000104413","Gene description":"Epithelial splicing regulatory protein 1","Uniprot":["Q6NXG1"],"Chromosome":"8","Position":"94641074-94707466","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["RNA-binding"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Intestinal goblet cells":"107.2","Suprabasal keratinocytes":"79.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"138.3","BEWO":"101.1","CAPAN-2":"140.8","hTCEpi":"226.5","OE19":"142.6","RT4":"99.1","T-47d":"108.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023719","HPA023720","HPA067104"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA023719":"AB_1856124","HPA023720":"AB_1856125","HPA067104":"AB_2685779"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.28e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.56e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.05e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.96e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"24.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"15.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"57.1","Tissue RNA - duodenum [nTPM]":"25.2","Tissue RNA - endometrium 1 [nTPM]":"3.4","Tissue RNA - epididymis [nTPM]":"29.6","Tissue RNA - esophagus [nTPM]":"64.2","Tissue RNA - fallopian tube [nTPM]":"21.3","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"8.5","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"15.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"42.6","Tissue RNA - parathyroid gland [nTPM]":"28.4","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"12.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"19.9","Tissue RNA - rectum [nTPM]":"62.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"10.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"60.6","Tissue RNA - small intestine [nTPM]":"22.0","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"38.6","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"36.6","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"15.3","Tissue RNA - urinary bladder [nTPM]":"22.5","Tissue RNA - vagina [nTPM]":"28.8","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"138.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"101.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"44.6","Cell RNA - CAPAN-2 [nTPM]":"140.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"81.6","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"70.9","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"226.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"10.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"67.3","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"12.4","Cell RNA - OE19 [nTPM]":"142.6","Cell RNA - PC-3 [nTPM]":"3.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"18.3","Cell RNA - RPTEC TERT1 [nTPM]":"17.4","Cell RNA - RT4 [nTPM]":"99.1","Cell RNA - SCLC-21H [nTPM]":"35.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"21.0","Cell RNA - SK-MEL-30 [nTPM]":"14.0","Cell RNA - SuSa [nTPM]":"21.4","Cell RNA - T-47d [nTPM]":"108.0","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"12.0","Cell RNA - U-266\/84 [nTPM]":"13.8","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"32.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"76.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.6","Single Cell Type RNA - Early spermatids [nTPM]":"12.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"69.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"58.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"107.2","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.2","Single Cell Type RNA - Late spermatids [nTPM]":"10.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.7","Single Cell Type RNA - Paneth cells [nTPM]":"48.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"71.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"79.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"62.1","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"73.9","Single Cell Type RNA - Urothelial cells [nTPM]":"40.1"},{"Gene":"ESRRB","Gene synonym":["DFNB35","ERR2","ERRb","ERRbeta","ESRL2","NR3B2"],"Ensembl":"ENSG00000119715","Gene description":"Estrogen related receptor beta","Uniprot":["O95718"],"Chromosome":"14","Position":"76310712-76501837","Protein class":["Disease related genes","Human disease related genes","Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Receptor"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"retina":"36.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"13.7","Early spermatids":"14.1","Horizontal cells":"55.5","Late spermatids":"37.6","Rod photoreceptor cells":"40.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"1.3","K-562":"5.0","U-266\/70":"2.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074772"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA074772":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"4.9","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"6.6","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"36.5","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"6.5","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"1.6","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"5.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"14.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"37.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"EYA4","Gene synonym":["CMD1J","DFNA10"],"Ensembl":"ENSG00000112319","Gene description":"EYA transcriptional coactivator and phosphatase 4","Uniprot":["O95677"],"Chromosome":"6","Position":"133240598-133532128","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Developmental protein","Hydrolase","Protein phosphatase"],"Disease involvement":["Cardiomyopathy","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"27.6","tongue":"21.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"46.0","Inhibitory neurons":"139.0","Oligodendrocytes":"79.2","Skeletal myocytes":"26.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"25.4","GAMG":"25.6","HeLa":"74.3","RH-30":"23.8","U-87 MG":"24.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004805","HPA038771","HPA038772"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA004805":"AB_10669750","HPA038771":"AB_10671865","HPA038772":"AB_10673119"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-9"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"2.6","Tissue RNA - choroid plexus [nTPM]":"13.3","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"5.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"5.7","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"27.6","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"3.3","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"2.1","Tissue RNA - tongue [nTPM]":"21.3","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"2.2","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"25.4","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"20.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.9","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"19.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"25.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"15.4","Cell RNA - HBEC3-KT [nTPM]":"6.7","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"20.2","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"74.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"5.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.4","Cell RNA - hTERT-HME1 [nTPM]":"4.5","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"10.7","Cell RNA - LHCN-M2 [nTPM]":"8.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"1.6","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"23.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.9","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"4.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"11.4","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"18.4","Cell RNA - U-266\/70 [nTPM]":"7.2","Cell RNA - U-266\/84 [nTPM]":"3.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"24.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"3.3","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"6.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"139.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"7.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"79.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.3","Single Cell Type RNA - Spermatocytes [nTPM]":"7.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"EYS","Gene synonym":["bA166P24.2","bA307F22.3","bA74E24.1","C6orf178","C6orf179","C6orf180","dJ1018A4.2","dJ303F19.1","EGFL10","EGFL11","RP25","SPAM"],"Ensembl":"ENSG00000188107","Gene description":"Eyes shut homolog","Uniprot":["Q5T1H1"],"Chromosome":"6","Position":"63719980-65707226","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"36","RNA tissue specific nTPM":{"retina":"24.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"316.9","Early spermatids":"87.3","Inhibitory neurons":"83.8","Late spermatids":"45.7","Rod photoreceptor cells":"140.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"1.5","SCLC-21H":"1.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"24.8","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"316.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"87.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"83.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"45.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"140.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"FA2H","Gene synonym":["FAAH","FAXDC1","FLJ25287","SPG35"],"Ensembl":"ENSG00000103089","Gene description":"Fatty acid 2-hydroxylase","Uniprot":["Q7L5A8"],"Chromosome":"16","Position":"74712955-74774831","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Leukodystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"183.9","stomach 1":"61.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"85.1","Oligodendrocyte precursor cells":"61.3","Oligodendrocytes":"307.9","Paneth cells":"75.2","Urothelial cells":"192.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"38.1","HAP1":"48.6","JURKAT":"89.8","OE19":"61.5","SK-BR-3":"28.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056614","HPA077840"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA056614":"AB_2683191","HPA077840":"AB_2686858"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.74e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.01e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"41.7","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"89.1","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"77.9","Tissue RNA - cerebral cortex [nTPM]":"63.0","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"11.7","Tissue RNA - colon [nTPM]":"21.2","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"17.8","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"46.1","Tissue RNA - hypothalamus [nTPM]":"56.1","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"129.2","Tissue RNA - midbrain [nTPM]":"79.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"10.1","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"106.0","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"19.4","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"11.0","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"8.5","Tissue RNA - small intestine [nTPM]":"14.4","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"65.2","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"61.1","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"75.2","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"26.3","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"183.9","Cell RNA - A-431 [nTPM]":"9.2","Cell RNA - A549 [nTPM]":"38.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"20.8","Cell RNA - CAPAN-2 [nTPM]":"21.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"3.6","Cell RNA - HAP1 [nTPM]":"48.6","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"89.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"15.2","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"61.5","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"23.4","Cell RNA - RT4 [nTPM]":"15.6","Cell RNA - SCLC-21H [nTPM]":"6.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"28.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"8.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"3.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"41.7","Brain RNA - basal ganglia [nTPM]":"89.1","Brain RNA - cerebellum [nTPM]":"77.9","Brain RNA - cerebral cortex [nTPM]":"63.0","Brain RNA - hippocampal formation [nTPM]":"46.1","Brain RNA - hypothalamus [nTPM]":"56.1","Brain RNA - medulla oblongata [nTPM]":"129.2","Brain RNA - midbrain [nTPM]":"79.6","Brain RNA - pons [nTPM]":"106.0","Brain RNA - spinal cord [nTPM]":"65.2","Brain RNA - thalamus [nTPM]":"75.2","Brain RNA - white matter [nTPM]":"183.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"14.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"43.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.5","Single Cell Type RNA - Early spermatids [nTPM]":"10.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"85.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"34.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"61.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"307.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.4","Single Cell Type RNA - Paneth cells [nTPM]":"75.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"6.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.3","Single Cell Type RNA - Urothelial cells [nTPM]":"192.8"},{"Gene":"FAM161A","Gene synonym":["FLJ13305","RP28"],"Ensembl":"ENSG00000170264","Gene description":"FAM161 centrosomal protein A","Uniprot":["Q3B820"],"Chromosome":"2","Position":"61824848-61854143","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"28.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"100.1","Early spermatids":"183.2","Late spermatids":"293.1","Rod photoreceptor cells":"417.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032119"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA032119":"AB_10602806"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.02e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"5.2","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"1.9","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"28.9","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"2.6","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"3.6","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"3.4","Cell RNA - A549 [nTPM]":"3.1","Cell RNA - AF22 [nTPM]":"7.1","Cell RNA - AN3-CA [nTPM]":"3.3","Cell RNA - ASC diff [nTPM]":"3.4","Cell RNA - ASC TERT1 [nTPM]":"3.2","Cell RNA - BEWO [nTPM]":"2.1","Cell RNA - BJ [nTPM]":"2.9","Cell RNA - BJ hTERT+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.2","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"6.6","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"6.1","Cell RNA - HaCaT [nTPM]":"1.6","Cell RNA - HAP1 [nTPM]":"4.3","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"8.0","Cell RNA - HDLM-2 [nTPM]":"4.5","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"2.8","Cell RNA - Hep G2 [nTPM]":"3.3","Cell RNA - HHSteC [nTPM]":"2.9","Cell RNA - HL-60 [nTPM]":"2.7","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"1.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.6","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.0","Cell RNA - HUVEC TERT2 [nTPM]":"3.7","Cell RNA - JURKAT [nTPM]":"6.4","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"2.5","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"4.9","Cell RNA - NB-4 [nTPM]":"5.2","Cell RNA - NTERA-2 [nTPM]":"11.0","Cell RNA - OE19 [nTPM]":"4.2","Cell RNA - PC-3 [nTPM]":"3.3","Cell RNA - REH [nTPM]":"8.4","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"3.3","Cell RNA - RPTEC TERT1 [nTPM]":"2.4","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"8.7","Cell RNA - SH-SY5Y [nTPM]":"7.3","Cell RNA - SiHa [nTPM]":"6.2","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"4.7","Cell RNA - SuSa [nTPM]":"6.7","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"4.2","Cell RNA - U-251 MG [nTPM]":"6.7","Cell RNA - U-266\/70 [nTPM]":"3.8","Cell RNA - U-266\/84 [nTPM]":"3.1","Cell RNA - U-698 [nTPM]":"8.1","Cell RNA - U-87 MG [nTPM]":"4.2","Cell RNA - U-937 [nTPM]":"4.5","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.7","Single Cell Type RNA - Astrocytes [nTPM]":"20.2","Single Cell Type RNA - B-cells [nTPM]":"3.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"49.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"100.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"183.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.8","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"42.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.6","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"293.1","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"42.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"4.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"47.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"417.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"98.0","Single Cell Type RNA - Spermatogonia [nTPM]":"39.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"16.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.5","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"FARS2","Gene synonym":["dJ236A3.1","FARS1","mtPheRS"],"Ensembl":"ENSG00000145982","Gene description":"Phenylalanyl-tRNA synthetase 2, mitochondrial","Uniprot":["O95363"],"Chromosome":"6","Position":"5261044-5829192","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"110.4","Early spermatids":"77.4","Excitatory neurons":"217.0","Inhibitory neurons":"122.6","Late spermatids":"78.8","Microglial cells":"106.8","Oligodendrocyte precursor cells":"186.5","Oligodendrocytes":"122.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018148","HPA028836"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018148":"AB_1848426","HPA028836":"AB_10601377"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.14e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"9.6","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"11.7","Tissue RNA - breast [nTPM]":"11.0","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"22.9","Tissue RNA - colon [nTPM]":"10.6","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"9.8","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"8.4","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"14.4","Tissue RNA - lung [nTPM]":"9.6","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"5.8","Tissue RNA - midbrain [nTPM]":"6.7","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"10.3","Tissue RNA - parathyroid gland [nTPM]":"13.2","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"8.9","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"11.3","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"8.6","Tissue RNA - skeletal muscle [nTPM]":"19.7","Tissue RNA - skin 1 [nTPM]":"11.4","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"9.8","Tissue RNA - stomach 1 [nTPM]":"9.9","Tissue RNA - testis [nTPM]":"11.7","Tissue RNA - thalamus [nTPM]":"10.8","Tissue RNA - thymus [nTPM]":"12.5","Tissue RNA - thyroid gland [nTPM]":"14.4","Tissue RNA - tongue [nTPM]":"17.9","Tissue RNA - tonsil [nTPM]":"11.0","Tissue RNA - urinary bladder [nTPM]":"8.8","Tissue RNA - vagina [nTPM]":"8.9","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"14.2","Cell RNA - A549 [nTPM]":"13.4","Cell RNA - AF22 [nTPM]":"14.1","Cell RNA - AN3-CA [nTPM]":"14.7","Cell RNA - ASC diff [nTPM]":"17.1","Cell RNA - ASC TERT1 [nTPM]":"20.5","Cell RNA - BEWO [nTPM]":"11.6","Cell RNA - BJ [nTPM]":"15.1","Cell RNA - BJ hTERT+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.2","Cell RNA - CACO-2 [nTPM]":"18.0","Cell RNA - CAPAN-2 [nTPM]":"10.7","Cell RNA - Daudi [nTPM]":"19.7","Cell RNA - EFO-21 [nTPM]":"23.1","Cell RNA - fHDF\/TERT166 [nTPM]":"14.9","Cell RNA - GAMG [nTPM]":"18.9","Cell RNA - HaCaT [nTPM]":"13.9","Cell RNA - HAP1 [nTPM]":"18.2","Cell RNA - HBEC3-KT [nTPM]":"23.9","Cell RNA - HBF TERT88 [nTPM]":"20.2","Cell RNA - HDLM-2 [nTPM]":"59.5","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"7.9","Cell RNA - HeLa [nTPM]":"11.0","Cell RNA - Hep G2 [nTPM]":"16.1","Cell RNA - HHSteC [nTPM]":"8.9","Cell RNA - HL-60 [nTPM]":"18.9","Cell RNA - HMC-1 [nTPM]":"11.4","Cell RNA - HSkMC [nTPM]":"16.5","Cell RNA - hTCEpi [nTPM]":"24.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.9","Cell RNA - hTERT-HME1 [nTPM]":"15.8","Cell RNA - hTERT-RPE1 [nTPM]":"11.4","Cell RNA - HUVEC TERT2 [nTPM]":"23.6","Cell RNA - JURKAT [nTPM]":"21.8","Cell RNA - K-562 [nTPM]":"23.7","Cell RNA - Karpas-707 [nTPM]":"4.5","Cell RNA - LHCN-M2 [nTPM]":"14.6","Cell RNA - MCF7 [nTPM]":"14.5","Cell RNA - MOLT-4 [nTPM]":"20.6","Cell RNA - NB-4 [nTPM]":"21.2","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"21.7","Cell RNA - PC-3 [nTPM]":"12.9","Cell RNA - REH [nTPM]":"20.0","Cell RNA - RH-30 [nTPM]":"17.6","Cell RNA - RPMI-8226 [nTPM]":"38.9","Cell RNA - RPTEC TERT1 [nTPM]":"18.7","Cell RNA - RT4 [nTPM]":"16.4","Cell RNA - SCLC-21H [nTPM]":"23.9","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"14.1","Cell RNA - SK-BR-3 [nTPM]":"11.0","Cell RNA - SK-MEL-30 [nTPM]":"17.6","Cell RNA - SuSa [nTPM]":"18.4","Cell RNA - T-47d [nTPM]":"22.1","Cell RNA - THP-1 [nTPM]":"20.6","Cell RNA - TIME [nTPM]":"13.7","Cell RNA - U-138 MG [nTPM]":"20.7","Cell RNA - U-2 OS [nTPM]":"9.4","Cell RNA - U-2197 [nTPM]":"12.3","Cell RNA - U-251 MG [nTPM]":"19.8","Cell RNA - U-266\/70 [nTPM]":"9.3","Cell RNA - U-266\/84 [nTPM]":"34.2","Cell RNA - U-698 [nTPM]":"10.9","Cell RNA - U-87 MG [nTPM]":"11.6","Cell RNA - U-937 [nTPM]":"11.1","Cell RNA - WM-115 [nTPM]":"26.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"14.7","Blood RNA - eosinophil [nTPM]":"5.2","Blood RNA - gdT-cell [nTPM]":"23.1","Blood RNA - intermediate monocyte [nTPM]":"16.7","Blood RNA - MAIT T-cell [nTPM]":"20.3","Blood RNA - memory B-cell [nTPM]":"20.0","Blood RNA - memory CD4 T-cell [nTPM]":"20.5","Blood RNA - memory CD8 T-cell [nTPM]":"21.2","Blood RNA - myeloid DC [nTPM]":"26.0","Blood RNA - naive B-cell [nTPM]":"17.5","Blood RNA - naive CD4 T-cell [nTPM]":"22.3","Blood RNA - naive CD8 T-cell [nTPM]":"22.1","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"24.6","Blood RNA - non-classical monocyte [nTPM]":"11.9","Blood RNA - plasmacytoid DC [nTPM]":"15.5","Blood RNA - T-reg [nTPM]":"28.0","Blood RNA - total PBMC [nTPM]":"17.6","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"8.4","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"5.8","Brain RNA - midbrain [nTPM]":"6.7","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"10.8","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"10.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.7","Single Cell Type RNA - Astrocytes [nTPM]":"110.4","Single Cell Type RNA - B-cells [nTPM]":"15.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"8.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"8.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.5","Single Cell Type RNA - dendritic cells [nTPM]":"10.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"14.6","Single Cell Type RNA - Early spermatids [nTPM]":"77.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.6","Single Cell Type RNA - Endothelial cells [nTPM]":"10.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"13.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"217.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.9","Single Cell Type RNA - Fibroblasts [nTPM]":"10.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.2","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"14.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"12.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"122.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.4","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.5","Single Cell Type RNA - Langerhans cells [nTPM]":"11.6","Single Cell Type RNA - Late spermatids [nTPM]":"78.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"17.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"106.8","Single Cell Type RNA - monocytes [nTPM]":"9.4","Single Cell Type RNA - Muller glia cells [nTPM]":"14.2","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"186.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"122.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.8","Single Cell Type RNA - Paneth cells [nTPM]":"8.6","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"16.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.8","Single Cell Type RNA - Spermatocytes [nTPM]":"19.2","Single Cell Type RNA - Spermatogonia [nTPM]":"9.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.7","Single Cell Type RNA - T-cells [nTPM]":"16.2","Single Cell Type RNA - Theca cells [nTPM]":"24.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.9","Single Cell Type RNA - Urothelial cells [nTPM]":"13.2"},{"Gene":"FAT2","Gene synonym":["CDHF8","CDHR9","HFAT2","MEGF1"],"Ensembl":"ENSG00000086570","Gene description":"FAT atypical cadherin 2","Uniprot":["Q9NYQ8"],"Chromosome":"5","Position":"151504093-151568944","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"113.4","esophagus":"50.9","skin 1":"56.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"18.0","Basal respiratory cells":"31.6","Basal squamous epithelial cells":"27.9","Early spermatids":"16.0","Extravillous trophoblasts":"20.6","Squamous epithelial cells":"53.2","Suprabasal keratinocytes":"19.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"cervical cancer":"13.9","head and neck cancer":"21.4","lung cancer":"6.1","urothelial cancer":"5.6"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebellum":"113.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"BEWO":"35.1","EFO-21":"21.0","HaCaT":"51.7","HBEC3-KT":"23.6","hTCEpi":"70.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"18","RNA mouse brain regional specific nTPM":{"cerebellum":"32.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"56","RNA pig brain regional specific nTPM":{"cerebellum":"224.4"},"Antibody":["CAB033680"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033680":"AB_2100956"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"113.4","Tissue RNA - cerebral cortex [nTPM]":"4.8","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"50.9","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"15.1","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"17.2","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"8.9","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"56.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"2.9","Tissue RNA - vagina [nTPM]":"24.4","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"1.7","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"35.1","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"21.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"51.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"23.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"70.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"3.8","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"4.8","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"1.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"113.4","Brain RNA - cerebral cortex [nTPM]":"4.8","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"15.1","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"17.2","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"11.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"16.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"13.0"},{"Gene":"FBLN5","Gene synonym":["ARMD3","DANCE","EVEC","UP50"],"Ensembl":"ENSG00000140092","Gene description":"Fibulin 5","Uniprot":["Q9UBX5"],"Chromosome":"14","Position":"91869411-91947987","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Age-related macular degeneration","Charcot-Marie-Tooth disease","Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Fibroblasts":"209.4","Leydig cells":"626.6","Peritubular cells":"794.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"6.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"6.6","T-cells":"1.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"457.1","ASC TERT1":"234.6","BJ":"202.0","BJ hTERT+":"202.5","fHDF\/TERT166":"394.6","HSkMC":"216.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000848","HPA000868","CAB025843"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB025843":null,"HPA000848":"AB_1078620","HPA000868":"AB_1078619"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.75e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Tissue RNA - adipose tissue [nTPM]":"182.2","Tissue RNA - adrenal gland [nTPM]":"73.4","Tissue RNA - amygdala [nTPM]":"10.7","Tissue RNA - appendix [nTPM]":"17.7","Tissue RNA - basal ganglia [nTPM]":"12.8","Tissue RNA - bone marrow [nTPM]":"7.5","Tissue RNA - breast [nTPM]":"110.4","Tissue RNA - cerebellum [nTPM]":"7.4","Tissue RNA - cerebral cortex [nTPM]":"12.5","Tissue RNA - cervix [nTPM]":"124.9","Tissue RNA - choroid plexus [nTPM]":"15.7","Tissue RNA - colon [nTPM]":"80.3","Tissue RNA - duodenum [nTPM]":"19.1","Tissue RNA - endometrium 1 [nTPM]":"178.4","Tissue RNA - epididymis [nTPM]":"40.0","Tissue RNA - esophagus [nTPM]":"26.8","Tissue RNA - fallopian tube [nTPM]":"143.0","Tissue RNA - gallbladder [nTPM]":"130.2","Tissue RNA - heart muscle [nTPM]":"211.1","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"8.6","Tissue RNA - kidney [nTPM]":"108.4","Tissue RNA - liver [nTPM]":"29.3","Tissue RNA - lung [nTPM]":"164.8","Tissue RNA - lymph node [nTPM]":"25.5","Tissue RNA - medulla oblongata [nTPM]":"15.5","Tissue RNA - midbrain [nTPM]":"10.9","Tissue RNA - ovary [nTPM]":"107.3","Tissue RNA - pancreas [nTPM]":"46.4","Tissue RNA - parathyroid gland [nTPM]":"16.8","Tissue RNA - pituitary gland [nTPM]":"14.5","Tissue RNA - placenta [nTPM]":"67.0","Tissue RNA - pons [nTPM]":"14.2","Tissue RNA - prostate [nTPM]":"49.0","Tissue RNA - rectum [nTPM]":"20.6","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"55.8","Tissue RNA - seminal vesicle [nTPM]":"70.9","Tissue RNA - skeletal muscle [nTPM]":"30.4","Tissue RNA - skin 1 [nTPM]":"66.9","Tissue RNA - small intestine [nTPM]":"52.7","Tissue RNA - smooth muscle [nTPM]":"88.7","Tissue RNA - spinal cord [nTPM]":"13.1","Tissue RNA - spleen [nTPM]":"130.9","Tissue RNA - stomach 1 [nTPM]":"68.9","Tissue RNA - testis [nTPM]":"35.6","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"21.8","Tissue RNA - thyroid gland [nTPM]":"79.5","Tissue RNA - tongue [nTPM]":"36.0","Tissue RNA - tonsil [nTPM]":"15.7","Tissue RNA - urinary bladder [nTPM]":"117.5","Tissue RNA - vagina [nTPM]":"93.3","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"457.1","Cell RNA - ASC TERT1 [nTPM]":"234.6","Cell RNA - BEWO [nTPM]":"22.5","Cell RNA - BJ [nTPM]":"202.0","Cell RNA - BJ hTERT+ [nTPM]":"202.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.5","Cell RNA - CACO-2 [nTPM]":"4.7","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.2","Cell RNA - fHDF\/TERT166 [nTPM]":"394.6","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"1.0","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.3","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"4.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"74.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"216.6","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.9","Cell RNA - hTERT-HME1 [nTPM]":"14.1","Cell RNA - hTERT-RPE1 [nTPM]":"2.8","Cell RNA - HUVEC TERT2 [nTPM]":"10.4","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"25.3","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"30.2","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"1.2","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"12.3","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"2.6","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"1.9","Cell RNA - U-138 MG [nTPM]":"3.2","Cell RNA - U-2 OS [nTPM]":"6.6","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"6.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"10.7","Brain RNA - basal ganglia [nTPM]":"12.8","Brain RNA - cerebellum [nTPM]":"7.4","Brain RNA - cerebral cortex [nTPM]":"12.5","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"8.6","Brain RNA - medulla oblongata [nTPM]":"15.5","Brain RNA - midbrain [nTPM]":"10.9","Brain RNA - pons [nTPM]":"14.2","Brain RNA - spinal cord [nTPM]":"13.1","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"31.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"11.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - dendritic cells [nTPM]":"2.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.7","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.4","Single Cell Type RNA - Endothelial cells [nTPM]":"15.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.5","Single Cell Type RNA - Fibroblasts [nTPM]":"209.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"18.4","Single Cell Type RNA - Late spermatids [nTPM]":"27.5","Single Cell Type RNA - Leydig cells [nTPM]":"626.6","Single Cell Type RNA - Macrophages [nTPM]":"5.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"794.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"15.5","Single Cell Type RNA - Theca cells [nTPM]":"3.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"FBXO38","Gene synonym":["Fbx38","FLJ13962","MOKA","SP329"],"Ensembl":"ENSG00000145868","Gene description":"F-box protein 38","Uniprot":["Q6PIJ6"],"Chromosome":"5","Position":"148383935-148442836","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034821","HPA041444"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Cytokinetic bridge","Cytosol"],"Antibody RRID":{"HPA034821":"AB_10669897","HPA041444":"AB_2677484"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Tissue RNA - adipose tissue [nTPM]":"12.8","Tissue RNA - adrenal gland [nTPM]":"11.5","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"12.9","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"9.8","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"8.1","Tissue RNA - cerebral cortex [nTPM]":"9.9","Tissue RNA - cervix [nTPM]":"14.1","Tissue RNA - choroid plexus [nTPM]":"8.2","Tissue RNA - colon [nTPM]":"12.5","Tissue RNA - duodenum [nTPM]":"9.6","Tissue RNA - endometrium 1 [nTPM]":"12.5","Tissue RNA - epididymis [nTPM]":"11.1","Tissue RNA - esophagus [nTPM]":"10.5","Tissue RNA - fallopian tube [nTPM]":"10.0","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"17.4","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"7.7","Tissue RNA - kidney [nTPM]":"12.9","Tissue RNA - liver [nTPM]":"18.0","Tissue RNA - lung [nTPM]":"14.5","Tissue RNA - lymph node [nTPM]":"14.6","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"10.2","Tissue RNA - placenta [nTPM]":"13.8","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"13.0","Tissue RNA - retina [nTPM]":"11.0","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"12.0","Tissue RNA - skeletal muscle [nTPM]":"18.7","Tissue RNA - skin 1 [nTPM]":"12.2","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"12.3","Tissue RNA - spinal cord [nTPM]":"7.5","Tissue RNA - spleen [nTPM]":"14.4","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"12.4","Tissue RNA - thalamus [nTPM]":"7.8","Tissue RNA - thymus [nTPM]":"20.2","Tissue RNA - thyroid gland [nTPM]":"12.2","Tissue RNA - tongue [nTPM]":"16.8","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"13.8","Tissue RNA - vagina [nTPM]":"11.2","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"12.6","Cell RNA - A549 [nTPM]":"13.2","Cell RNA - AF22 [nTPM]":"20.1","Cell RNA - AN3-CA [nTPM]":"14.7","Cell RNA - ASC diff [nTPM]":"22.1","Cell RNA - ASC TERT1 [nTPM]":"24.6","Cell RNA - BEWO [nTPM]":"10.4","Cell RNA - BJ [nTPM]":"16.1","Cell RNA - BJ hTERT+ [nTPM]":"30.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.5","Cell RNA - CACO-2 [nTPM]":"19.6","Cell RNA - CAPAN-2 [nTPM]":"15.1","Cell RNA - Daudi [nTPM]":"18.2","Cell RNA - EFO-21 [nTPM]":"15.5","Cell RNA - fHDF\/TERT166 [nTPM]":"26.2","Cell RNA - GAMG [nTPM]":"23.6","Cell RNA - HaCaT [nTPM]":"17.2","Cell RNA - HAP1 [nTPM]":"21.2","Cell RNA - HBEC3-KT [nTPM]":"20.3","Cell RNA - HBF TERT88 [nTPM]":"26.8","Cell RNA - HDLM-2 [nTPM]":"20.1","Cell RNA - HEK 293 [nTPM]":"13.6","Cell RNA - HEL [nTPM]":"10.8","Cell RNA - HeLa [nTPM]":"19.0","Cell RNA - Hep G2 [nTPM]":"13.3","Cell RNA - HHSteC [nTPM]":"21.9","Cell RNA - HL-60 [nTPM]":"29.6","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"24.0","Cell RNA - hTCEpi [nTPM]":"17.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.6","Cell RNA - hTERT-HME1 [nTPM]":"21.1","Cell RNA - hTERT-RPE1 [nTPM]":"24.0","Cell RNA - HUVEC TERT2 [nTPM]":"30.7","Cell RNA - JURKAT [nTPM]":"16.6","Cell RNA - K-562 [nTPM]":"12.2","Cell RNA - Karpas-707 [nTPM]":"19.1","Cell RNA - LHCN-M2 [nTPM]":"22.3","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"18.8","Cell RNA - NB-4 [nTPM]":"13.8","Cell RNA - NTERA-2 [nTPM]":"9.4","Cell RNA - OE19 [nTPM]":"13.9","Cell RNA - PC-3 [nTPM]":"19.8","Cell RNA - REH [nTPM]":"16.6","Cell RNA - RH-30 [nTPM]":"29.3","Cell RNA - RPMI-8226 [nTPM]":"18.4","Cell RNA - RPTEC TERT1 [nTPM]":"21.7","Cell RNA - RT4 [nTPM]":"14.5","Cell RNA - SCLC-21H [nTPM]":"17.9","Cell RNA - SH-SY5Y [nTPM]":"17.3","Cell RNA - SiHa [nTPM]":"21.4","Cell RNA - SK-BR-3 [nTPM]":"14.2","Cell RNA - SK-MEL-30 [nTPM]":"21.2","Cell RNA - SuSa [nTPM]":"17.1","Cell RNA - T-47d [nTPM]":"15.0","Cell RNA - THP-1 [nTPM]":"21.2","Cell RNA - TIME [nTPM]":"20.2","Cell RNA - U-138 MG [nTPM]":"20.4","Cell RNA - U-2 OS [nTPM]":"7.3","Cell RNA - U-2197 [nTPM]":"10.8","Cell RNA - U-251 MG [nTPM]":"18.2","Cell RNA - U-266\/70 [nTPM]":"23.3","Cell RNA - U-266\/84 [nTPM]":"25.1","Cell RNA - U-698 [nTPM]":"15.3","Cell RNA - U-87 MG [nTPM]":"20.3","Cell RNA - U-937 [nTPM]":"16.6","Cell RNA - WM-115 [nTPM]":"15.8","Blood RNA - basophil [nTPM]":"15.1","Blood RNA - classical monocyte [nTPM]":"6.1","Blood RNA - eosinophil [nTPM]":"9.1","Blood RNA - gdT-cell [nTPM]":"5.0","Blood RNA - intermediate monocyte [nTPM]":"8.0","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"4.7","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"7.5","Blood RNA - naive B-cell [nTPM]":"3.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.8","Blood RNA - naive CD8 T-cell [nTPM]":"6.2","Blood RNA - neutrophil [nTPM]":"11.2","Blood RNA - NK-cell [nTPM]":"7.7","Blood RNA - non-classical monocyte [nTPM]":"15.2","Blood RNA - plasmacytoid DC [nTPM]":"3.7","Blood RNA - T-reg [nTPM]":"7.4","Blood RNA - total PBMC [nTPM]":"4.9","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"8.1","Brain RNA - cerebral cortex [nTPM]":"9.9","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"7.7","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"7.5","Brain RNA - thalamus [nTPM]":"7.8","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"10.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.7","Single Cell Type RNA - Astrocytes [nTPM]":"25.1","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"10.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"10.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - dendritic cells [nTPM]":"13.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.8","Single Cell Type RNA - Early spermatids [nTPM]":"11.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.9","Single Cell Type RNA - Endothelial cells [nTPM]":"10.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.8","Single Cell Type RNA - Fibroblasts [nTPM]":"11.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.4","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"9.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"16.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.6","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"24.9","Single Cell Type RNA - Langerhans cells [nTPM]":"6.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"17.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"12.3","Single Cell Type RNA - Muller glia cells [nTPM]":"5.9","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.9","Single Cell Type RNA - Paneth cells [nTPM]":"8.9","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"11.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.8","Single Cell Type RNA - Spermatocytes [nTPM]":"20.6","Single Cell Type RNA - Spermatogonia [nTPM]":"8.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.3","Single Cell Type RNA - T-cells [nTPM]":"12.1","Single Cell Type RNA - Theca cells [nTPM]":"11.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.0","Single Cell Type RNA - Urothelial cells [nTPM]":"8.7"},{"Gene":"FBXO7","Gene synonym":["Fbx","FBX7","PARK15"],"Ensembl":"ENSG00000100225","Gene description":"F-box protein 7","Uniprot":["Q9Y3I1"],"Chromosome":"22","Position":"32474676-32498829","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"279.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"680.9","Late spermatids":"620.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032113","HPA032114","CAB034296"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"550000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034296":"AB_2102563","HPA032113":"AB_2674156","HPA032114":"AB_10696202"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.08e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.66e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Tissue RNA - adipose tissue [nTPM]":"51.6","Tissue RNA - adrenal gland [nTPM]":"61.7","Tissue RNA - amygdala [nTPM]":"70.3","Tissue RNA - appendix [nTPM]":"35.9","Tissue RNA - basal ganglia [nTPM]":"86.8","Tissue RNA - bone marrow [nTPM]":"279.9","Tissue RNA - breast [nTPM]":"52.9","Tissue RNA - cerebellum [nTPM]":"79.9","Tissue RNA - cerebral cortex [nTPM]":"86.5","Tissue RNA - cervix [nTPM]":"53.5","Tissue RNA - choroid plexus [nTPM]":"72.3","Tissue RNA - colon [nTPM]":"53.5","Tissue RNA - duodenum [nTPM]":"47.7","Tissue RNA - endometrium 1 [nTPM]":"49.2","Tissue RNA - epididymis [nTPM]":"68.7","Tissue RNA - esophagus [nTPM]":"40.1","Tissue RNA - fallopian tube [nTPM]":"66.6","Tissue RNA - gallbladder [nTPM]":"43.9","Tissue RNA - heart muscle [nTPM]":"38.5","Tissue RNA - hippocampal formation [nTPM]":"68.3","Tissue RNA - hypothalamus [nTPM]":"76.2","Tissue RNA - kidney [nTPM]":"106.5","Tissue RNA - liver [nTPM]":"128.4","Tissue RNA - lung [nTPM]":"59.6","Tissue RNA - lymph node [nTPM]":"54.6","Tissue RNA - medulla oblongata [nTPM]":"85.0","Tissue RNA - midbrain [nTPM]":"83.8","Tissue RNA - ovary [nTPM]":"62.7","Tissue RNA - pancreas [nTPM]":"41.0","Tissue RNA - parathyroid gland [nTPM]":"75.9","Tissue RNA - pituitary gland [nTPM]":"50.6","Tissue RNA - placenta [nTPM]":"71.5","Tissue RNA - pons [nTPM]":"84.1","Tissue RNA - prostate [nTPM]":"42.6","Tissue RNA - rectum [nTPM]":"53.8","Tissue RNA - retina [nTPM]":"40.1","Tissue RNA - salivary gland [nTPM]":"43.1","Tissue RNA - seminal vesicle [nTPM]":"53.5","Tissue RNA - skeletal muscle [nTPM]":"31.0","Tissue RNA - skin 1 [nTPM]":"50.6","Tissue RNA - small intestine [nTPM]":"48.4","Tissue RNA - smooth muscle [nTPM]":"57.1","Tissue RNA - spinal cord [nTPM]":"79.0","Tissue RNA - spleen [nTPM]":"65.6","Tissue RNA - stomach 1 [nTPM]":"48.4","Tissue RNA - testis [nTPM]":"99.5","Tissue RNA - thalamus [nTPM]":"79.8","Tissue RNA - thymus [nTPM]":"77.9","Tissue RNA - thyroid gland [nTPM]":"134.2","Tissue RNA - tongue [nTPM]":"48.3","Tissue RNA - tonsil [nTPM]":"61.8","Tissue RNA - urinary bladder [nTPM]":"54.8","Tissue RNA - vagina [nTPM]":"44.0","Tissue RNA - white matter [nTPM]":"97.8","Cell RNA - A-431 [nTPM]":"72.1","Cell RNA - A549 [nTPM]":"52.1","Cell RNA - AF22 [nTPM]":"69.3","Cell RNA - AN3-CA [nTPM]":"77.1","Cell RNA - ASC diff [nTPM]":"105.8","Cell RNA - ASC TERT1 [nTPM]":"99.5","Cell RNA - BEWO [nTPM]":"45.9","Cell RNA - BJ [nTPM]":"64.3","Cell RNA - BJ hTERT+ [nTPM]":"119.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"102.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"121.9","Cell RNA - CACO-2 [nTPM]":"54.4","Cell RNA - CAPAN-2 [nTPM]":"51.1","Cell RNA - Daudi [nTPM]":"71.2","Cell RNA - EFO-21 [nTPM]":"49.6","Cell RNA - fHDF\/TERT166 [nTPM]":"114.6","Cell RNA - GAMG [nTPM]":"87.8","Cell RNA - HaCaT [nTPM]":"47.6","Cell RNA - HAP1 [nTPM]":"103.3","Cell RNA - HBEC3-KT [nTPM]":"84.7","Cell RNA - HBF TERT88 [nTPM]":"105.1","Cell RNA - HDLM-2 [nTPM]":"111.8","Cell RNA - HEK 293 [nTPM]":"80.9","Cell RNA - HEL [nTPM]":"99.1","Cell RNA - HeLa [nTPM]":"54.4","Cell RNA - Hep G2 [nTPM]":"83.7","Cell RNA - HHSteC [nTPM]":"126.8","Cell RNA - HL-60 [nTPM]":"126.2","Cell RNA - HMC-1 [nTPM]":"82.8","Cell RNA - HSkMC [nTPM]":"83.8","Cell RNA - hTCEpi [nTPM]":"134.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"90.6","Cell RNA - hTERT-HME1 [nTPM]":"69.2","Cell RNA - hTERT-RPE1 [nTPM]":"93.4","Cell RNA - HUVEC TERT2 [nTPM]":"112.2","Cell RNA - JURKAT [nTPM]":"53.1","Cell RNA - K-562 [nTPM]":"77.5","Cell RNA - Karpas-707 [nTPM]":"88.0","Cell RNA - LHCN-M2 [nTPM]":"112.7","Cell RNA - MCF7 [nTPM]":"57.7","Cell RNA - MOLT-4 [nTPM]":"65.3","Cell RNA - NB-4 [nTPM]":"81.2","Cell RNA - NTERA-2 [nTPM]":"26.7","Cell RNA - OE19 [nTPM]":"102.3","Cell RNA - PC-3 [nTPM]":"36.1","Cell RNA - REH [nTPM]":"64.1","Cell RNA - RH-30 [nTPM]":"72.2","Cell RNA - RPMI-8226 [nTPM]":"84.0","Cell RNA - RPTEC TERT1 [nTPM]":"118.2","Cell RNA - RT4 [nTPM]":"81.0","Cell RNA - SCLC-21H [nTPM]":"96.6","Cell RNA - SH-SY5Y [nTPM]":"63.1","Cell RNA - SiHa [nTPM]":"81.3","Cell RNA - SK-BR-3 [nTPM]":"62.4","Cell RNA - SK-MEL-30 [nTPM]":"235.2","Cell RNA - SuSa [nTPM]":"98.3","Cell RNA - T-47d [nTPM]":"34.0","Cell RNA - THP-1 [nTPM]":"67.2","Cell RNA - TIME [nTPM]":"76.0","Cell RNA - U-138 MG [nTPM]":"50.6","Cell RNA - U-2 OS [nTPM]":"69.4","Cell RNA - U-2197 [nTPM]":"48.4","Cell RNA - U-251 MG [nTPM]":"49.5","Cell RNA - U-266\/70 [nTPM]":"62.1","Cell RNA - U-266\/84 [nTPM]":"69.3","Cell RNA - U-698 [nTPM]":"67.6","Cell RNA - U-87 MG [nTPM]":"97.4","Cell RNA - U-937 [nTPM]":"65.6","Cell RNA - WM-115 [nTPM]":"212.3","Blood RNA - basophil [nTPM]":"251.5","Blood RNA - classical monocyte [nTPM]":"59.9","Blood RNA - eosinophil [nTPM]":"132.1","Blood RNA - gdT-cell [nTPM]":"83.3","Blood RNA - intermediate monocyte [nTPM]":"70.6","Blood RNA - MAIT T-cell [nTPM]":"101.5","Blood RNA - memory B-cell [nTPM]":"70.2","Blood RNA - memory CD4 T-cell [nTPM]":"75.9","Blood RNA - memory CD8 T-cell [nTPM]":"84.9","Blood RNA - myeloid DC [nTPM]":"82.2","Blood RNA - naive B-cell [nTPM]":"63.6","Blood RNA - naive CD4 T-cell [nTPM]":"65.6","Blood RNA - naive CD8 T-cell [nTPM]":"72.6","Blood RNA - neutrophil [nTPM]":"22.4","Blood RNA - NK-cell [nTPM]":"98.3","Blood RNA - non-classical monocyte [nTPM]":"74.9","Blood RNA - plasmacytoid DC [nTPM]":"55.8","Blood RNA - T-reg [nTPM]":"101.3","Blood RNA - total PBMC [nTPM]":"90.4","Brain RNA - amygdala [nTPM]":"70.3","Brain RNA - basal ganglia [nTPM]":"86.8","Brain RNA - cerebellum [nTPM]":"79.9","Brain RNA - cerebral cortex [nTPM]":"86.5","Brain RNA - hippocampal formation [nTPM]":"68.3","Brain RNA - hypothalamus [nTPM]":"76.2","Brain RNA - medulla oblongata [nTPM]":"85.0","Brain RNA - midbrain [nTPM]":"83.8","Brain RNA - pons [nTPM]":"84.1","Brain RNA - spinal cord [nTPM]":"79.0","Brain RNA - thalamus [nTPM]":"79.8","Brain RNA - white matter [nTPM]":"97.8","Single Cell Type RNA - Adipocytes [nTPM]":"48.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.3","Single Cell Type RNA - Astrocytes [nTPM]":"37.9","Single Cell Type RNA - B-cells [nTPM]":"60.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"69.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"72.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"48.9","Single Cell Type RNA - Bipolar cells [nTPM]":"26.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"46.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"65.8","Single Cell Type RNA - Club cells [nTPM]":"48.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"90.2","Single Cell Type RNA - dendritic cells [nTPM]":"73.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"43.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"97.8","Single Cell Type RNA - Ductal cells [nTPM]":"75.3","Single Cell Type RNA - Early spermatids [nTPM]":"303.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.8","Single Cell Type RNA - Endothelial cells [nTPM]":"53.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"67.6","Single Cell Type RNA - Erythroid cells [nTPM]":"680.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"77.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"108.9","Single Cell Type RNA - Fibroblasts [nTPM]":"47.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.2","Single Cell Type RNA - granulocytes [nTPM]":"55.8","Single Cell Type RNA - Granulosa cells [nTPM]":"63.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.9","Single Cell Type RNA - Hepatocytes [nTPM]":"88.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"71.9","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"42.7","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"64.8","Single Cell Type RNA - Langerhans cells [nTPM]":"53.2","Single Cell Type RNA - Late spermatids [nTPM]":"620.8","Single Cell Type RNA - Leydig cells [nTPM]":"45.1","Single Cell Type RNA - Macrophages [nTPM]":"55.0","Single Cell Type RNA - Melanocytes [nTPM]":"119.2","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"125.2","Single Cell Type RNA - Muller glia cells [nTPM]":"54.1","Single Cell Type RNA - NK-cells [nTPM]":"72.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"101.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"170.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"77.2","Single Cell Type RNA - Paneth cells [nTPM]":"58.0","Single Cell Type RNA - Peritubular cells [nTPM]":"48.9","Single Cell Type RNA - Plasma cells [nTPM]":"62.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"68.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"72.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"152.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.1","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.2","Single Cell Type RNA - Spermatocytes [nTPM]":"149.4","Single Cell Type RNA - Spermatogonia [nTPM]":"136.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"42.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"71.6","Single Cell Type RNA - T-cells [nTPM]":"62.3","Single Cell Type RNA - Theca cells [nTPM]":"41.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.2","Single Cell Type RNA - Urothelial cells [nTPM]":"83.7"},{"Gene":"FDXR","Gene synonym":["ADR","ADXR"],"Ensembl":"ENSG00000161513","Gene description":"Ferredoxin reductase","Uniprot":["P22570"],"Chromosome":"17","Position":"74862497-74873031","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Electron transport","Lipid metabolism","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Deafness","Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"adrenal gland":"343.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Granulosa cells":"329.3","Theca cells":"794.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"89.5","Hep G2":"173.5"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008597","CAB009818","HPA044393","HPA053673"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB008597":"AB_1615557","CAB009818":"AB_2102601","HPA044393":"AB_2678927","HPA053673":"AB_2682225"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.38e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.9","Tissue RNA - adrenal gland [nTPM]":"343.1","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"2.4","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"3.8","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"8.1","Tissue RNA - cervix [nTPM]":"7.8","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"9.7","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"6.7","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"26.0","Tissue RNA - fallopian tube [nTPM]":"12.9","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"6.5","Tissue RNA - liver [nTPM]":"14.9","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"20.5","Tissue RNA - pancreas [nTPM]":"12.9","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"16.4","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"7.4","Tissue RNA - spleen [nTPM]":"33.9","Tissue RNA - stomach 1 [nTPM]":"7.6","Tissue RNA - testis [nTPM]":"45.6","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"6.2","Tissue RNA - vagina [nTPM]":"10.5","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"12.5","Cell RNA - A549 [nTPM]":"65.6","Cell RNA - AF22 [nTPM]":"9.6","Cell RNA - AN3-CA [nTPM]":"10.8","Cell RNA - ASC diff [nTPM]":"6.8","Cell RNA - ASC TERT1 [nTPM]":"9.1","Cell RNA - BEWO [nTPM]":"89.5","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"15.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.1","Cell RNA - CACO-2 [nTPM]":"18.3","Cell RNA - CAPAN-2 [nTPM]":"10.8","Cell RNA - Daudi [nTPM]":"29.6","Cell RNA - EFO-21 [nTPM]":"2.6","Cell RNA - fHDF\/TERT166 [nTPM]":"6.2","Cell RNA - GAMG [nTPM]":"4.8","Cell RNA - HaCaT [nTPM]":"24.9","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"18.4","Cell RNA - HBF TERT88 [nTPM]":"2.5","Cell RNA - HDLM-2 [nTPM]":"27.9","Cell RNA - HEK 293 [nTPM]":"15.2","Cell RNA - HEL [nTPM]":"22.6","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"173.5","Cell RNA - HHSteC [nTPM]":"19.0","Cell RNA - HL-60 [nTPM]":"5.0","Cell RNA - HMC-1 [nTPM]":"75.1","Cell RNA - HSkMC [nTPM]":"29.2","Cell RNA - hTCEpi [nTPM]":"20.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.1","Cell RNA - hTERT-HME1 [nTPM]":"3.1","Cell RNA - hTERT-RPE1 [nTPM]":"7.0","Cell RNA - HUVEC TERT2 [nTPM]":"43.9","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"36.1","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"13.4","Cell RNA - MCF7 [nTPM]":"53.4","Cell RNA - MOLT-4 [nTPM]":"19.7","Cell RNA - NB-4 [nTPM]":"10.6","Cell RNA - NTERA-2 [nTPM]":"5.5","Cell RNA - OE19 [nTPM]":"11.8","Cell RNA - PC-3 [nTPM]":"14.5","Cell RNA - REH [nTPM]":"10.6","Cell RNA - RH-30 [nTPM]":"16.4","Cell RNA - RPMI-8226 [nTPM]":"16.2","Cell RNA - RPTEC TERT1 [nTPM]":"7.1","Cell RNA - RT4 [nTPM]":"21.0","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"12.1","Cell RNA - SiHa [nTPM]":"10.0","Cell RNA - SK-BR-3 [nTPM]":"21.7","Cell RNA - SK-MEL-30 [nTPM]":"11.2","Cell RNA - SuSa [nTPM]":"10.9","Cell RNA - T-47d [nTPM]":"47.4","Cell RNA - THP-1 [nTPM]":"4.7","Cell RNA - TIME [nTPM]":"20.5","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"51.9","Cell RNA - U-2197 [nTPM]":"9.4","Cell RNA - U-251 MG [nTPM]":"7.4","Cell RNA - U-266\/70 [nTPM]":"12.7","Cell RNA - U-266\/84 [nTPM]":"2.3","Cell RNA - U-698 [nTPM]":"6.5","Cell RNA - U-87 MG [nTPM]":"16.1","Cell RNA - U-937 [nTPM]":"7.7","Cell RNA - WM-115 [nTPM]":"20.6","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"6.0","Blood RNA - eosinophil [nTPM]":"5.0","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"4.5","Blood RNA - MAIT T-cell [nTPM]":"5.0","Blood RNA - memory B-cell [nTPM]":"4.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"7.3","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.4","Blood RNA - naive CD8 T-cell [nTPM]":"5.4","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"10.3","Blood RNA - non-classical monocyte [nTPM]":"3.4","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"15.4","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"8.1","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"7.4","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"4.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"23.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.3","Single Cell Type RNA - Endothelial cells [nTPM]":"4.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.1","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.9","Single Cell Type RNA - Fibroblasts [nTPM]":"12.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.5","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"329.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"13.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.1","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"6.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"14.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"4.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"11.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.0","Single Cell Type RNA - Paneth cells [nTPM]":"16.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"7.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"73.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.1","Single Cell Type RNA - T-cells [nTPM]":"8.6","Single Cell Type RNA - Theca cells [nTPM]":"794.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.3","Single Cell Type RNA - Urothelial cells [nTPM]":"17.4"},{"Gene":"FGA","Gene synonym":[],"Ensembl":"ENSG00000171560","Gene description":"Fibrinogen alpha chain","Uniprot":["P02671"],"Chromosome":"4","Position":"154583128-154590745","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Blood coagulation","Hemostasis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Amyloidosis","Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"388","RNA tissue specific nTPM":{"liver":"18396.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"41","RNA single cell type specific nTPM":{"Hepatocytes":"17365.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"43","RNA cancer specific FPKM":{"liver cancer":"2431.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"Hep G2":"429.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016776","HPA051370","HPA064755"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":407000000,"Blood concentration - Conc. blood MS [pg\/L]":"140000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB016776":null,"HPA051370":"AB_2681458","HPA064755":"AB_2685345"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.33e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.23e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"1.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"18.8","Tissue RNA - liver [nTPM]":"18396.9","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"18.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"47.4","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"28.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"24.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"2.7","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"3.4","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"429.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"6.3","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"2.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"6.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"3.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.8","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.9","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"27.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"414.6","Single Cell Type RNA - Club cells [nTPM]":"3.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"38.6","Single Cell Type RNA - Early spermatids [nTPM]":"28.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"205.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"238.8","Single Cell Type RNA - Hepatocytes [nTPM]":"17365.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"328.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"46.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"17.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"17.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FGD4","Gene synonym":["CMT4H","frabin","FRABP","ZFYVE6"],"Ensembl":"ENSG00000139132","Gene description":"FYVE, RhoGEF and PH domain containing 4","Uniprot":["Q96M96"],"Chromosome":"12","Position":"32399558-32646050","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding","Guanine-nucleotide releasing factor"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"232.5","Early spermatids":"196.3","Late spermatids":"250.1","Microglial cells":"203.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"14.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"3.6","granulocytes":"8.4","monocytes":"5.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"24.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039235"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA039235":"AB_10673420"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Tissue RNA - adipose tissue [nTPM]":"12.6","Tissue RNA - adrenal gland [nTPM]":"4.3","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"12.1","Tissue RNA - breast [nTPM]":"8.0","Tissue RNA - cerebellum [nTPM]":"11.4","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"6.1","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"9.4","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"2.3","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"4.9","Tissue RNA - gallbladder [nTPM]":"10.3","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"10.3","Tissue RNA - kidney [nTPM]":"10.8","Tissue RNA - liver [nTPM]":"17.7","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"12.3","Tissue RNA - midbrain [nTPM]":"10.1","Tissue RNA - ovary [nTPM]":"24.6","Tissue RNA - pancreas [nTPM]":"9.4","Tissue RNA - parathyroid gland [nTPM]":"14.8","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"10.4","Tissue RNA - pons [nTPM]":"12.4","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"10.1","Tissue RNA - retina [nTPM]":"23.6","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"10.8","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"8.2","Tissue RNA - smooth muscle [nTPM]":"3.4","Tissue RNA - spinal cord [nTPM]":"9.2","Tissue RNA - spleen [nTPM]":"5.2","Tissue RNA - stomach 1 [nTPM]":"28.9","Tissue RNA - testis [nTPM]":"12.1","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"1.7","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"10.8","Tissue RNA - tonsil [nTPM]":"2.7","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"13.7","Cell RNA - A-431 [nTPM]":"5.4","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"6.6","Cell RNA - AN3-CA [nTPM]":"2.0","Cell RNA - ASC diff [nTPM]":"24.1","Cell RNA - ASC TERT1 [nTPM]":"14.8","Cell RNA - BEWO [nTPM]":"8.1","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"22.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"8.1","Cell RNA - CAPAN-2 [nTPM]":"8.3","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"2.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"2.8","Cell RNA - HaCaT [nTPM]":"5.1","Cell RNA - HAP1 [nTPM]":"5.3","Cell RNA - HBEC3-KT [nTPM]":"7.5","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"4.7","Cell RNA - HeLa [nTPM]":"2.7","Cell RNA - Hep G2 [nTPM]":"2.5","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"8.8","Cell RNA - hTCEpi [nTPM]":"10.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"12.9","Cell RNA - hTERT-RPE1 [nTPM]":"3.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.6","Cell RNA - JURKAT [nTPM]":"1.1","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"5.4","Cell RNA - LHCN-M2 [nTPM]":"15.6","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.7","Cell RNA - NTERA-2 [nTPM]":"17.4","Cell RNA - OE19 [nTPM]":"5.3","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"6.9","Cell RNA - RPMI-8226 [nTPM]":"16.2","Cell RNA - RPTEC TERT1 [nTPM]":"8.0","Cell RNA - RT4 [nTPM]":"5.3","Cell RNA - SCLC-21H [nTPM]":"7.2","Cell RNA - SH-SY5Y [nTPM]":"8.5","Cell RNA - SiHa [nTPM]":"4.7","Cell RNA - SK-BR-3 [nTPM]":"4.4","Cell RNA - SK-MEL-30 [nTPM]":"6.6","Cell RNA - SuSa [nTPM]":"11.8","Cell RNA - T-47d [nTPM]":"7.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"13.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"18.8","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"1.9","Cell RNA - U-266\/84 [nTPM]":"4.6","Cell RNA - U-698 [nTPM]":"2.9","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"2.8","Cell RNA - WM-115 [nTPM]":"5.2","Blood RNA - basophil [nTPM]":"3.6","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"8.4","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"5.5","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"11.4","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"10.3","Brain RNA - medulla oblongata [nTPM]":"12.3","Brain RNA - midbrain [nTPM]":"10.1","Brain RNA - pons [nTPM]":"12.4","Brain RNA - spinal cord [nTPM]":"9.2","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"13.7","Single Cell Type RNA - Adipocytes [nTPM]":"84.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.4","Single Cell Type RNA - Astrocytes [nTPM]":"232.5","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"23.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"18.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"118.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"57.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"16.8","Single Cell Type RNA - Early spermatids [nTPM]":"196.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"24.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.8","Single Cell Type RNA - Fibroblasts [nTPM]":"19.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"78.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"65.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"34.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"37.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.8","Single Cell Type RNA - Horizontal cells [nTPM]":"70.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.2","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"71.7","Single Cell Type RNA - Langerhans cells [nTPM]":"22.3","Single Cell Type RNA - Late spermatids [nTPM]":"250.1","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"92.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"203.3","Single Cell Type RNA - monocytes [nTPM]":"39.9","Single Cell Type RNA - Muller glia cells [nTPM]":"79.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"16.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"54.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"114.5","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.4","Single Cell Type RNA - Spermatogonia [nTPM]":"7.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"25.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.5","Single Cell Type RNA - Urothelial cells [nTPM]":"20.2"},{"Gene":"FGF12","Gene synonym":["FGF12B","FHF1"],"Ensembl":"ENSG00000114279","Gene description":"Fibroblast growth factor 12","Uniprot":["P61328"],"Chromosome":"3","Position":"192139390-192767764","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"35.8","heart muscle":"131.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"413.7","Excitatory neurons":"1213.5","Inhibitory neurons":"1925.1","Oligodendrocyte precursor cells":"1668.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"15.1","NTERA-2":"10.3","SCLC-21H":"23.9","U-251 MG":"14.7","WM-115":"17.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071557"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA071557":"AB_2686417"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"35.8","Tissue RNA - amygdala [nTPM]":"8.5","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"21.3","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"131.3","Tissue RNA - hippocampal formation [nTPM]":"17.5","Tissue RNA - hypothalamus [nTPM]":"14.2","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"11.1","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"15.4","Tissue RNA - salivary gland [nTPM]":"5.9","Tissue RNA - seminal vesicle [nTPM]":"6.0","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"11.6","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"15.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"7.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"3.2","Cell RNA - HeLa [nTPM]":"6.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"10.3","Cell RNA - OE19 [nTPM]":"7.1","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"1.8","Cell RNA - SCLC-21H [nTPM]":"23.9","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"1.1","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"6.2","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"14.7","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"2.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"17.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.5","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"21.3","Brain RNA - hippocampal formation [nTPM]":"17.5","Brain RNA - hypothalamus [nTPM]":"14.2","Brain RNA - medulla oblongata [nTPM]":"11.1","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"17.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"42.7","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"100.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"413.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"20.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1213.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"18.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1925.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"38.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"46.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1668.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.0","Single Cell Type RNA - Spermatogonia [nTPM]":"8.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"38.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"FGF14","Gene synonym":["FHF4","SCA27"],"Ensembl":"ENSG00000102466","Gene description":"Fibroblast growth factor 14","Uniprot":["Q92915"],"Chromosome":"13","Position":"101710804-102402457","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.4","cervix":"7.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"31","RNA single cell type specific nTPM":{"Excitatory neurons":"1994.2","Inhibitory neurons":"2754.3","Oligodendrocyte precursor cells":"2271.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"1.0","SH-SY5Y":"5.8","U-87 MG":"1.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049828"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA049828":"AB_2680901"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"3.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"2.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"11.4","Tissue RNA - cerebral cortex [nTPM]":"5.1","Tissue RNA - cervix [nTPM]":"7.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"2.7","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"7.7","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"4.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"5.8","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.2","Brain RNA - basal ganglia [nTPM]":"2.6","Brain RNA - cerebellum [nTPM]":"11.4","Brain RNA - cerebral cortex [nTPM]":"5.1","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"7.7","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"4.5","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"74.4","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"33.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"18.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1994.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"9.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2754.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"35.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.2","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2271.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"FIG4","Gene synonym":["ALS11","CMT4J","dJ249I4.1","hSac3","KIAA0274","SAC3"],"Ensembl":"ENSG00000112367","Gene description":"FIG4 phosphoinositide 5-phosphatase","Uniprot":["Q92562"],"Chromosome":"6","Position":"109690609-109878098","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Amyotrophic lateral sclerosis","Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"49.5","Oligodendrocyte precursor cells":"46.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017823","HPA068859"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Vesicles","Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"CAB017823":null,"HPA068859":"AB_2686049"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.91e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.42e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"10.2","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"8.2","Tissue RNA - choroid plexus [nTPM]":"12.9","Tissue RNA - colon [nTPM]":"10.1","Tissue RNA - duodenum [nTPM]":"5.0","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"9.4","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"7.6","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"8.8","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"6.1","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"10.1","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"17.4","Tissue RNA - pituitary gland [nTPM]":"11.9","Tissue RNA - placenta [nTPM]":"8.8","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"9.5","Tissue RNA - retina [nTPM]":"10.8","Tissue RNA - salivary gland [nTPM]":"10.7","Tissue RNA - seminal vesicle [nTPM]":"7.8","Tissue RNA - skeletal muscle [nTPM]":"10.6","Tissue RNA - skin 1 [nTPM]":"7.6","Tissue RNA - small intestine [nTPM]":"9.1","Tissue RNA - smooth muscle [nTPM]":"10.3","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"13.8","Tissue RNA - stomach 1 [nTPM]":"8.7","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"6.1","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"9.3","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"10.1","Tissue RNA - urinary bladder [nTPM]":"9.2","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"7.0","Cell RNA - A-431 [nTPM]":"8.3","Cell RNA - A549 [nTPM]":"8.4","Cell RNA - AF22 [nTPM]":"11.7","Cell RNA - AN3-CA [nTPM]":"14.9","Cell RNA - ASC diff [nTPM]":"11.8","Cell RNA - ASC TERT1 [nTPM]":"17.2","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"9.9","Cell RNA - BJ hTERT+ [nTPM]":"14.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.2","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"7.2","Cell RNA - Daudi [nTPM]":"23.2","Cell RNA - EFO-21 [nTPM]":"5.8","Cell RNA - fHDF\/TERT166 [nTPM]":"18.9","Cell RNA - GAMG [nTPM]":"14.9","Cell RNA - HaCaT [nTPM]":"5.2","Cell RNA - HAP1 [nTPM]":"12.6","Cell RNA - HBEC3-KT [nTPM]":"8.5","Cell RNA - HBF TERT88 [nTPM]":"20.7","Cell RNA - HDLM-2 [nTPM]":"13.3","Cell RNA - HEK 293 [nTPM]":"16.5","Cell RNA - HEL [nTPM]":"10.9","Cell RNA - HeLa [nTPM]":"5.9","Cell RNA - Hep G2 [nTPM]":"5.5","Cell RNA - HHSteC [nTPM]":"11.4","Cell RNA - HL-60 [nTPM]":"9.5","Cell RNA - HMC-1 [nTPM]":"10.0","Cell RNA - HSkMC [nTPM]":"8.8","Cell RNA - hTCEpi [nTPM]":"9.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.8","Cell RNA - hTERT-HME1 [nTPM]":"10.6","Cell RNA - hTERT-RPE1 [nTPM]":"22.8","Cell RNA - HUVEC TERT2 [nTPM]":"18.3","Cell RNA - JURKAT [nTPM]":"13.9","Cell RNA - K-562 [nTPM]":"6.8","Cell RNA - Karpas-707 [nTPM]":"8.8","Cell RNA - LHCN-M2 [nTPM]":"12.7","Cell RNA - MCF7 [nTPM]":"6.8","Cell RNA - MOLT-4 [nTPM]":"12.0","Cell RNA - NB-4 [nTPM]":"8.4","Cell RNA - NTERA-2 [nTPM]":"5.9","Cell RNA - OE19 [nTPM]":"12.0","Cell RNA - PC-3 [nTPM]":"4.7","Cell RNA - REH [nTPM]":"7.9","Cell RNA - RH-30 [nTPM]":"6.1","Cell RNA - RPMI-8226 [nTPM]":"7.3","Cell RNA - RPTEC TERT1 [nTPM]":"13.3","Cell RNA - RT4 [nTPM]":"18.4","Cell RNA - SCLC-21H [nTPM]":"12.8","Cell RNA - SH-SY5Y [nTPM]":"11.7","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"10.7","Cell RNA - SK-MEL-30 [nTPM]":"21.1","Cell RNA - SuSa [nTPM]":"15.6","Cell RNA - T-47d [nTPM]":"6.0","Cell RNA - THP-1 [nTPM]":"23.1","Cell RNA - TIME [nTPM]":"11.2","Cell RNA - U-138 MG [nTPM]":"4.2","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"5.4","Cell RNA - U-251 MG [nTPM]":"9.5","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"2.6","Cell RNA - U-698 [nTPM]":"7.9","Cell RNA - U-87 MG [nTPM]":"27.3","Cell RNA - U-937 [nTPM]":"8.5","Cell RNA - WM-115 [nTPM]":"4.6","Blood RNA - basophil [nTPM]":"15.4","Blood RNA - classical monocyte [nTPM]":"24.9","Blood RNA - eosinophil [nTPM]":"14.2","Blood RNA - gdT-cell [nTPM]":"8.8","Blood RNA - intermediate monocyte [nTPM]":"24.5","Blood RNA - MAIT T-cell [nTPM]":"7.7","Blood RNA - memory B-cell [nTPM]":"18.9","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"8.5","Blood RNA - myeloid DC [nTPM]":"19.2","Blood RNA - naive B-cell [nTPM]":"21.2","Blood RNA - naive CD4 T-cell [nTPM]":"7.5","Blood RNA - naive CD8 T-cell [nTPM]":"7.5","Blood RNA - neutrophil [nTPM]":"7.4","Blood RNA - NK-cell [nTPM]":"10.0","Blood RNA - non-classical monocyte [nTPM]":"15.2","Blood RNA - plasmacytoid DC [nTPM]":"8.1","Blood RNA - T-reg [nTPM]":"9.4","Blood RNA - total PBMC [nTPM]":"11.7","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"8.8","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"6.1","Brain RNA - white matter [nTPM]":"7.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.0","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"15.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"8.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"6.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.4","Single Cell Type RNA - dendritic cells [nTPM]":"9.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"18.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.9","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"4.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.8","Single Cell Type RNA - Late spermatids [nTPM]":"17.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"17.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"16.4","Single Cell Type RNA - Muller glia cells [nTPM]":"8.5","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"46.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"6.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"6.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"12.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.3","Single Cell Type RNA - T-cells [nTPM]":"9.3","Single Cell Type RNA - Theca cells [nTPM]":"5.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8.9"},{"Gene":"FLVCR1","Gene synonym":["AXPC1","FLVCR","MFSD7B","PCA","SLC49A1"],"Ensembl":"ENSG00000162769","Gene description":"FLVCR heme transporter 1","Uniprot":["Q9Y5Y0"],"Chromosome":"1","Position":"212858275-212899363","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Erythrocyte maturation","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"19.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"73.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"55.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046646"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA046646":"AB_2679735"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"6.2","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"9.7","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"2.4","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"3.6","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"7.0","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"19.4","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"4.8","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"2.2","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"8.4","Cell RNA - A549 [nTPM]":"11.0","Cell RNA - AF22 [nTPM]":"16.8","Cell RNA - AN3-CA [nTPM]":"5.1","Cell RNA - ASC diff [nTPM]":"2.8","Cell RNA - ASC TERT1 [nTPM]":"3.4","Cell RNA - BEWO [nTPM]":"31.3","Cell RNA - BJ [nTPM]":"2.4","Cell RNA - BJ hTERT+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.9","Cell RNA - CACO-2 [nTPM]":"16.1","Cell RNA - CAPAN-2 [nTPM]":"15.2","Cell RNA - Daudi [nTPM]":"9.1","Cell RNA - EFO-21 [nTPM]":"4.4","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"10.2","Cell RNA - HaCaT [nTPM]":"12.5","Cell RNA - HAP1 [nTPM]":"18.2","Cell RNA - HBEC3-KT [nTPM]":"5.4","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"5.4","Cell RNA - HEK 293 [nTPM]":"8.0","Cell RNA - HEL [nTPM]":"5.4","Cell RNA - HeLa [nTPM]":"10.4","Cell RNA - Hep G2 [nTPM]":"14.9","Cell RNA - HHSteC [nTPM]":"3.2","Cell RNA - HL-60 [nTPM]":"14.5","Cell RNA - HMC-1 [nTPM]":"8.4","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"3.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.2","Cell RNA - hTERT-HME1 [nTPM]":"6.6","Cell RNA - hTERT-RPE1 [nTPM]":"2.5","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"6.4","Cell RNA - K-562 [nTPM]":"14.7","Cell RNA - Karpas-707 [nTPM]":"7.4","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"4.1","Cell RNA - NB-4 [nTPM]":"7.2","Cell RNA - NTERA-2 [nTPM]":"55.3","Cell RNA - OE19 [nTPM]":"11.1","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"9.0","Cell RNA - RH-30 [nTPM]":"15.4","Cell RNA - RPMI-8226 [nTPM]":"10.6","Cell RNA - RPTEC TERT1 [nTPM]":"6.0","Cell RNA - RT4 [nTPM]":"8.0","Cell RNA - SCLC-21H [nTPM]":"18.1","Cell RNA - SH-SY5Y [nTPM]":"12.7","Cell RNA - SiHa [nTPM]":"11.2","Cell RNA - SK-BR-3 [nTPM]":"11.1","Cell RNA - SK-MEL-30 [nTPM]":"10.4","Cell RNA - SuSa [nTPM]":"13.8","Cell RNA - T-47d [nTPM]":"18.2","Cell RNA - THP-1 [nTPM]":"6.7","Cell RNA - TIME [nTPM]":"2.2","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"5.6","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"11.2","Cell RNA - U-266\/70 [nTPM]":"4.6","Cell RNA - U-266\/84 [nTPM]":"9.9","Cell RNA - U-698 [nTPM]":"10.8","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"8.3","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"6.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.0","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"8.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"24.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"12.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"9.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"32.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"8.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.6","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"20.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"9.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.5","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"9.6","Single Cell Type RNA - Late spermatids [nTPM]":"6.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"9.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"12.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"6.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"73.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"10.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"8.3","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.2","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"FOLR1","Gene synonym":["FOLR","FR\u00c3\u017d\u00c2\u00b1"],"Ensembl":"ENSG00000110195","Gene description":"Folate receptor alpha","Uniprot":["P15328"],"Chromosome":"11","Position":"72189558-72196323","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"480.2","fallopian tube":"187.2","lung":"193.5","salivary gland":"219.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"496.8","Alveolar cells type 2":"213.3","Breast glandular cells":"211.3","Club cells":"276.3","Collecting duct cells":"318.2","Cytotrophoblasts":"462.2","Proximal tubular cells":"366.0","Syncytiotrophoblasts":"259.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"259.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"HeLa":"444.2","RPTEC TERT1":"476.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077030"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":448000,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA077030":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.50e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"28.3","Tissue RNA - cerebellum [nTPM]":"11.8","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"123.5","Tissue RNA - choroid plexus [nTPM]":"480.2","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"3.4","Tissue RNA - fallopian tube [nTPM]":"187.2","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"153.0","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"193.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"5.7","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"7.1","Tissue RNA - parathyroid gland [nTPM]":"17.5","Tissue RNA - pituitary gland [nTPM]":"8.1","Tissue RNA - placenta [nTPM]":"36.2","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"219.5","Tissue RNA - seminal vesicle [nTPM]":"15.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"2.5","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"33.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"45.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"64.7","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"44.5","Cell RNA - CAPAN-2 [nTPM]":"46.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"45.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.9","Cell RNA - HAP1 [nTPM]":"2.4","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"444.2","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"15.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"476.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"3.0","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"7.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"38.5","Cell RNA - T-47d [nTPM]":"65.7","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"11.8","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"5.7","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"496.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"213.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"80.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"211.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"62.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"276.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"318.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"462.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"133.1","Single Cell Type RNA - Ductal cells [nTPM]":"14.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.3","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"110.9","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"87.5","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"3.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"366.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"149.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"259.0","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"10.4"},{"Gene":"FOXE3","Gene synonym":["FKHL12","FREAC8"],"Ensembl":"ENSG00000186790","Gene description":"Forkhead box E3","Uniprot":["Q13461"],"Chromosome":"1","Position":"47416285-47418052","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Aortic aneurysm","Cataract","Disease variant","Peters anomaly"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Cardiomyocytes":"6.0","Spermatogonia":"2.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"0.5","testis cancer":"1.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"SuSa":"10.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"10.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FRMD7","Gene synonym":["FLJ43346","NYS","NYS1"],"Ensembl":"ENSG00000165694","Gene description":"FERM domain containing 7","Uniprot":["Q6ZUT3"],"Chromosome":"X","Position":"132076990-132128020","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Neurogenesis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"endometrium 1":"2.9","kidney":"2.7","smooth muscle":"2.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Distal tubular cells":"9.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-87 MG":"1.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"28","RNA mouse brain regional specific nTPM":{"olfactory bulb":"65.7"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"86","RNA pig brain regional specific nTPM":{"olfactory bulb":"21.3"},"Antibody":["HPA000886"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA000886":"AB_1079269"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"2.7","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FRRS1L","Gene synonym":["C9orf4","CG-6"],"Ensembl":"ENSG00000260230","Gene description":"Ferric chelate reductase 1 like","Uniprot":["Q9P0K9"],"Chromosome":"9","Position":"109130293-109167249","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.6","ovary":"11.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"59.1","Excitatory neurons":"91.6","Horizontal cells":"97.6","Inhibitory neurons":"81.3","Oligodendrocyte precursor cells":"27.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"1.6","SH-SY5Y":"3.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071086"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA071086":"AB_2686342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"7.8","Tissue RNA - amygdala [nTPM]":"15.1","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"16.6","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"9.2","Tissue RNA - cerebral cortex [nTPM]":"17.3","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"18.6","Tissue RNA - hypothalamus [nTPM]":"15.4","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"11.0","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"3.1","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"6.9","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"15.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"7.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"1.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"3.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"15.1","Brain RNA - basal ganglia [nTPM]":"16.6","Brain RNA - cerebellum [nTPM]":"9.2","Brain RNA - cerebral cortex [nTPM]":"17.3","Brain RNA - hippocampal formation [nTPM]":"18.6","Brain RNA - hypothalamus [nTPM]":"15.4","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"6.9","Brain RNA - thalamus [nTPM]":"15.4","Brain RNA - white matter [nTPM]":"7.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"59.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"7.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"91.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"16.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"97.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"81.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"16.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"10.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"FSCN2","Gene synonym":["RFSN","RP30"],"Ensembl":"ENSG00000186765","Gene description":"Fascin actin-bundling protein 2, retinal","Uniprot":["O14926"],"Chromosome":"17","Position":"81528377-81537130","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"4.5","retina":"8.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"25.0","Exocrine glandular cells":"12.0","Rod photoreceptor cells":"25.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"1.9","T-47d":"2.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079270"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079270":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"1.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FTL","Gene synonym":["MGC71996","NBIA3"],"Ensembl":"ENSG00000087086","Gene description":"Ferritin light chain","Uniprot":["P02792"],"Chromosome":"19","Position":"48965309-48966879","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Iron storage"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Cataract","Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"14422.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"74983.4","Kupffer cells":"70127.1","Macrophages":"34584.5","Proximal tubular cells":"58047.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"125209.0","monocytes":"102128.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"24796.9","HSkMC":"20811.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020769","HPA041602"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB020769":null,"HPA041602":"AB_2677575"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.40e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Tissue RNA - adipose tissue [nTPM]":"6778.7","Tissue RNA - adrenal gland [nTPM]":"3262.2","Tissue RNA - amygdala [nTPM]":"6806.2","Tissue RNA - appendix [nTPM]":"2353.2","Tissue RNA - basal ganglia [nTPM]":"7172.4","Tissue RNA - bone marrow [nTPM]":"4213.8","Tissue RNA - breast [nTPM]":"4226.0","Tissue RNA - cerebellum [nTPM]":"6782.1","Tissue RNA - cerebral cortex [nTPM]":"10053.2","Tissue RNA - cervix [nTPM]":"2094.3","Tissue RNA - choroid plexus [nTPM]":"6429.7","Tissue RNA - colon [nTPM]":"2451.1","Tissue RNA - duodenum [nTPM]":"2427.0","Tissue RNA - endometrium 1 [nTPM]":"1523.4","Tissue RNA - epididymis [nTPM]":"1010.8","Tissue RNA - esophagus [nTPM]":"1306.2","Tissue RNA - fallopian tube [nTPM]":"2169.9","Tissue RNA - gallbladder [nTPM]":"4298.0","Tissue RNA - heart muscle [nTPM]":"2537.3","Tissue RNA - hippocampal formation [nTPM]":"6497.7","Tissue RNA - hypothalamus [nTPM]":"6998.4","Tissue RNA - kidney [nTPM]":"8845.6","Tissue RNA - liver [nTPM]":"14422.9","Tissue RNA - lung [nTPM]":"7261.1","Tissue RNA - lymph node [nTPM]":"3353.2","Tissue RNA - medulla oblongata [nTPM]":"7250.8","Tissue RNA - midbrain [nTPM]":"6998.4","Tissue RNA - ovary [nTPM]":"2455.3","Tissue RNA - pancreas [nTPM]":"2166.2","Tissue RNA - parathyroid gland [nTPM]":"931.7","Tissue RNA - pituitary gland [nTPM]":"1730.4","Tissue RNA - placenta [nTPM]":"3423.2","Tissue RNA - pons [nTPM]":"7218.5","Tissue RNA - prostate [nTPM]":"1946.5","Tissue RNA - rectum [nTPM]":"1800.0","Tissue RNA - retina [nTPM]":"684.9","Tissue RNA - salivary gland [nTPM]":"1663.5","Tissue RNA - seminal vesicle [nTPM]":"1390.4","Tissue RNA - skeletal muscle [nTPM]":"1345.9","Tissue RNA - skin 1 [nTPM]":"1449.7","Tissue RNA - small intestine [nTPM]":"2806.6","Tissue RNA - smooth muscle [nTPM]":"1842.3","Tissue RNA - spinal cord [nTPM]":"7149.5","Tissue RNA - spleen [nTPM]":"6751.4","Tissue RNA - stomach 1 [nTPM]":"3204.5","Tissue RNA - testis [nTPM]":"455.9","Tissue RNA - thalamus [nTPM]":"7581.8","Tissue RNA - thymus [nTPM]":"1168.9","Tissue RNA - thyroid gland [nTPM]":"3000.4","Tissue RNA - tongue [nTPM]":"1072.0","Tissue RNA - tonsil [nTPM]":"1334.6","Tissue RNA - urinary bladder [nTPM]":"4239.9","Tissue RNA - vagina [nTPM]":"1804.7","Tissue RNA - white matter [nTPM]":"7334.0","Cell RNA - A-431 [nTPM]":"869.7","Cell RNA - A549 [nTPM]":"12906.5","Cell RNA - AF22 [nTPM]":"949.6","Cell RNA - AN3-CA [nTPM]":"1457.0","Cell RNA - ASC diff [nTPM]":"16013.9","Cell RNA - ASC TERT1 [nTPM]":"16478.6","Cell RNA - BEWO [nTPM]":"1693.1","Cell RNA - BJ [nTPM]":"2194.1","Cell RNA - BJ hTERT+ [nTPM]":"12820.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3090.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6903.8","Cell RNA - CACO-2 [nTPM]":"2852.3","Cell RNA - CAPAN-2 [nTPM]":"3413.2","Cell RNA - Daudi [nTPM]":"656.4","Cell RNA - EFO-21 [nTPM]":"4104.3","Cell RNA - fHDF\/TERT166 [nTPM]":"13203.9","Cell RNA - GAMG [nTPM]":"6755.6","Cell RNA - HaCaT [nTPM]":"505.8","Cell RNA - HAP1 [nTPM]":"788.2","Cell RNA - HBEC3-KT [nTPM]":"1301.8","Cell RNA - HBF TERT88 [nTPM]":"2765.6","Cell RNA - HDLM-2 [nTPM]":"8895.0","Cell RNA - HEK 293 [nTPM]":"507.6","Cell RNA - HEL [nTPM]":"1740.0","Cell RNA - HeLa [nTPM]":"3222.8","Cell RNA - Hep G2 [nTPM]":"18949.7","Cell RNA - HHSteC [nTPM]":"24796.9","Cell RNA - HL-60 [nTPM]":"4133.3","Cell RNA - HMC-1 [nTPM]":"5591.2","Cell RNA - HSkMC [nTPM]":"20811.1","Cell RNA - hTCEpi [nTPM]":"1735.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5272.5","Cell RNA - hTERT-HME1 [nTPM]":"2301.6","Cell RNA - hTERT-RPE1 [nTPM]":"4590.4","Cell RNA - HUVEC TERT2 [nTPM]":"4549.8","Cell RNA - JURKAT [nTPM]":"774.6","Cell RNA - K-562 [nTPM]":"3284.9","Cell RNA - Karpas-707 [nTPM]":"1328.2","Cell RNA - LHCN-M2 [nTPM]":"6198.4","Cell RNA - MCF7 [nTPM]":"213.0","Cell RNA - MOLT-4 [nTPM]":"1152.1","Cell RNA - NB-4 [nTPM]":"2402.8","Cell RNA - NTERA-2 [nTPM]":"1729.8","Cell RNA - OE19 [nTPM]":"15140.6","Cell RNA - PC-3 [nTPM]":"1306.9","Cell RNA - REH [nTPM]":"947.6","Cell RNA - RH-30 [nTPM]":"643.0","Cell RNA - RPMI-8226 [nTPM]":"6763.9","Cell RNA - RPTEC TERT1 [nTPM]":"1989.7","Cell RNA - RT4 [nTPM]":"545.0","Cell RNA - SCLC-21H [nTPM]":"1209.9","Cell RNA - SH-SY5Y [nTPM]":"701.5","Cell RNA - SiHa [nTPM]":"5761.7","Cell RNA - SK-BR-3 [nTPM]":"313.4","Cell RNA - SK-MEL-30 [nTPM]":"1239.5","Cell RNA - SuSa [nTPM]":"5104.1","Cell RNA - T-47d [nTPM]":"183.2","Cell RNA - THP-1 [nTPM]":"8493.4","Cell RNA - TIME [nTPM]":"3438.3","Cell RNA - U-138 MG [nTPM]":"3353.4","Cell RNA - U-2 OS [nTPM]":"1740.1","Cell RNA - U-2197 [nTPM]":"4364.3","Cell RNA - U-251 MG [nTPM]":"3083.1","Cell RNA - U-266\/70 [nTPM]":"5690.2","Cell RNA - U-266\/84 [nTPM]":"13742.1","Cell RNA - U-698 [nTPM]":"625.1","Cell RNA - U-87 MG [nTPM]":"3563.9","Cell RNA - U-937 [nTPM]":"4334.7","Cell RNA - WM-115 [nTPM]":"6017.7","Blood RNA - basophil [nTPM]":"64938.4","Blood RNA - classical monocyte [nTPM]":"71067.8","Blood RNA - eosinophil [nTPM]":"77353.0","Blood RNA - gdT-cell [nTPM]":"6560.6","Blood RNA - intermediate monocyte [nTPM]":"102128.9","Blood RNA - MAIT T-cell [nTPM]":"7527.7","Blood RNA - memory B-cell [nTPM]":"17097.3","Blood RNA - memory CD4 T-cell [nTPM]":"7247.4","Blood RNA - memory CD8 T-cell [nTPM]":"7054.3","Blood RNA - myeloid DC [nTPM]":"25176.6","Blood RNA - naive B-cell [nTPM]":"15607.2","Blood RNA - naive CD4 T-cell [nTPM]":"8656.4","Blood RNA - naive CD8 T-cell [nTPM]":"7466.9","Blood RNA - neutrophil [nTPM]":"125209.0","Blood RNA - NK-cell [nTPM]":"4978.3","Blood RNA - non-classical monocyte [nTPM]":"91398.0","Blood RNA - plasmacytoid DC [nTPM]":"10579.6","Blood RNA - T-reg [nTPM]":"9634.4","Blood RNA - total PBMC [nTPM]":"94147.5","Brain RNA - amygdala [nTPM]":"6806.2","Brain RNA - basal ganglia [nTPM]":"7172.4","Brain RNA - cerebellum [nTPM]":"6782.1","Brain RNA - cerebral cortex [nTPM]":"10053.2","Brain RNA - hippocampal formation [nTPM]":"6497.7","Brain RNA - hypothalamus [nTPM]":"6998.4","Brain RNA - medulla oblongata [nTPM]":"7250.8","Brain RNA - midbrain [nTPM]":"6998.4","Brain RNA - pons [nTPM]":"7218.5","Brain RNA - spinal cord [nTPM]":"7149.5","Brain RNA - thalamus [nTPM]":"7581.8","Brain RNA - white matter [nTPM]":"7334.0","Single Cell Type RNA - Adipocytes [nTPM]":"2757.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1125.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3379.9","Single Cell Type RNA - Astrocytes [nTPM]":"88.5","Single Cell Type RNA - B-cells [nTPM]":"3311.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2793.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6799.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2785.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2159.8","Single Cell Type RNA - Bipolar cells [nTPM]":"474.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2597.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3977.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"777.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4398.0","Single Cell Type RNA - Club cells [nTPM]":"2550.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"2021.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"177.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"941.5","Single Cell Type RNA - dendritic cells [nTPM]":"2199.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"2314.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"10704.0","Single Cell Type RNA - Ductal cells [nTPM]":"4251.2","Single Cell Type RNA - Early spermatids [nTPM]":"290.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"504.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1413.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4867.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1613.4","Single Cell Type RNA - Erythroid cells [nTPM]":"4331.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"60.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6134.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1447.8","Single Cell Type RNA - Fibroblasts [nTPM]":"5703.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1715.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"617.4","Single Cell Type RNA - granulocytes [nTPM]":"2365.7","Single Cell Type RNA - Granulosa cells [nTPM]":"942.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4598.0","Single Cell Type RNA - Hepatocytes [nTPM]":"23702.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"74983.4","Single Cell Type RNA - Horizontal cells [nTPM]":"533.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"113.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2368.8","Single Cell Type RNA - Ionocytes [nTPM]":"3039.4","Single Cell Type RNA - Kupffer cells [nTPM]":"70127.1","Single Cell Type RNA - Langerhans cells [nTPM]":"16939.0","Single Cell Type RNA - Late spermatids [nTPM]":"1601.8","Single Cell Type RNA - Leydig cells [nTPM]":"4175.9","Single Cell Type RNA - Macrophages [nTPM]":"34584.5","Single Cell Type RNA - Melanocytes [nTPM]":"5085.3","Single Cell Type RNA - Microglial cells [nTPM]":"129.3","Single Cell Type RNA - monocytes [nTPM]":"22965.8","Single Cell Type RNA - Muller glia cells [nTPM]":"3161.9","Single Cell Type RNA - NK-cells [nTPM]":"2020.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"55.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"309.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6905.5","Single Cell Type RNA - Paneth cells [nTPM]":"5604.7","Single Cell Type RNA - Peritubular cells [nTPM]":"2010.8","Single Cell Type RNA - Plasma cells [nTPM]":"4884.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9790.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21474.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"58047.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1908.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"682.6","Single Cell Type RNA - Sertoli cells [nTPM]":"1341.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1643.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3455.6","Single Cell Type RNA - Spermatocytes [nTPM]":"82.1","Single Cell Type RNA - Spermatogonia [nTPM]":"311.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1985.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2226.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1502.7","Single Cell Type RNA - T-cells [nTPM]":"2590.4","Single Cell Type RNA - Theca cells [nTPM]":"1492.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2816.8","Single Cell Type RNA - Urothelial cells [nTPM]":"13083.6"},{"Gene":"FUS","Gene synonym":["ALS6","FUS1","hnRNP-P2","HNRNPP2","TLS"],"Ensembl":"ENSG00000089280","Gene description":"FUS RNA binding protein","Uniprot":["P35637"],"Chromosome":"16","Position":"31180138-31191605","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["DNA-binding","RNA-binding"],"Disease involvement":["Amyotrophic lateral sclerosis","Cancer-related genes","Disease variant","Neurodegeneration","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008784","CAB033036","CAB058691"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"480000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB033036":"AB_2105208","CAB058691":"AB_2665583","HPA008784":"AB_1849181"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.38e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"88.6","Tissue RNA - adrenal gland [nTPM]":"47.6","Tissue RNA - amygdala [nTPM]":"43.6","Tissue RNA - appendix [nTPM]":"102.9","Tissue RNA - basal ganglia [nTPM]":"48.6","Tissue RNA - bone marrow [nTPM]":"98.9","Tissue RNA - breast [nTPM]":"65.1","Tissue RNA - cerebellum [nTPM]":"50.6","Tissue RNA - cerebral cortex [nTPM]":"59.2","Tissue RNA - cervix [nTPM]":"85.3","Tissue RNA - choroid plexus [nTPM]":"27.2","Tissue RNA - colon [nTPM]":"72.5","Tissue RNA - duodenum [nTPM]":"59.5","Tissue RNA - endometrium 1 [nTPM]":"102.0","Tissue RNA - epididymis [nTPM]":"40.9","Tissue RNA - esophagus [nTPM]":"58.5","Tissue RNA - fallopian tube [nTPM]":"99.2","Tissue RNA - gallbladder [nTPM]":"38.8","Tissue RNA - heart muscle [nTPM]":"70.4","Tissue RNA - hippocampal formation [nTPM]":"46.9","Tissue RNA - hypothalamus [nTPM]":"48.6","Tissue RNA - kidney [nTPM]":"83.6","Tissue RNA - liver [nTPM]":"54.3","Tissue RNA - lung [nTPM]":"64.8","Tissue RNA - lymph node [nTPM]":"97.9","Tissue RNA - medulla oblongata [nTPM]":"44.3","Tissue RNA - midbrain [nTPM]":"43.0","Tissue RNA - ovary [nTPM]":"134.2","Tissue RNA - pancreas [nTPM]":"57.3","Tissue RNA - parathyroid gland [nTPM]":"85.0","Tissue RNA - pituitary gland [nTPM]":"47.2","Tissue RNA - placenta [nTPM]":"58.3","Tissue RNA - pons [nTPM]":"46.9","Tissue RNA - prostate [nTPM]":"59.1","Tissue RNA - rectum [nTPM]":"62.8","Tissue RNA - retina [nTPM]":"59.4","Tissue RNA - salivary gland [nTPM]":"60.0","Tissue RNA - seminal vesicle [nTPM]":"70.4","Tissue RNA - skeletal muscle [nTPM]":"98.6","Tissue RNA - skin 1 [nTPM]":"53.8","Tissue RNA - small intestine [nTPM]":"62.6","Tissue RNA - smooth muscle [nTPM]":"98.1","Tissue RNA - spinal cord [nTPM]":"45.7","Tissue RNA - spleen [nTPM]":"69.3","Tissue RNA - stomach 1 [nTPM]":"59.4","Tissue RNA - testis [nTPM]":"69.1","Tissue RNA - thalamus [nTPM]":"44.8","Tissue RNA - thymus [nTPM]":"174.1","Tissue RNA - thyroid gland [nTPM]":"58.6","Tissue RNA - tongue [nTPM]":"86.0","Tissue RNA - tonsil [nTPM]":"113.2","Tissue RNA - urinary bladder [nTPM]":"87.5","Tissue RNA - vagina [nTPM]":"63.2","Tissue RNA - white matter [nTPM]":"52.1","Cell RNA - A-431 [nTPM]":"386.6","Cell RNA - A549 [nTPM]":"337.2","Cell RNA - AF22 [nTPM]":"492.6","Cell RNA - AN3-CA [nTPM]":"292.9","Cell RNA - ASC diff [nTPM]":"128.3","Cell RNA - ASC TERT1 [nTPM]":"101.7","Cell RNA - BEWO [nTPM]":"429.3","Cell RNA - BJ [nTPM]":"504.1","Cell RNA - BJ hTERT+ [nTPM]":"253.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"319.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"238.3","Cell RNA - CACO-2 [nTPM]":"440.7","Cell RNA - CAPAN-2 [nTPM]":"254.9","Cell RNA - Daudi [nTPM]":"579.6","Cell RNA - EFO-21 [nTPM]":"359.3","Cell RNA - fHDF\/TERT166 [nTPM]":"310.7","Cell RNA - GAMG [nTPM]":"349.4","Cell RNA - HaCaT [nTPM]":"173.0","Cell RNA - HAP1 [nTPM]":"563.6","Cell RNA - HBEC3-KT [nTPM]":"421.0","Cell RNA - HBF TERT88 [nTPM]":"284.3","Cell RNA - HDLM-2 [nTPM]":"341.5","Cell RNA - HEK 293 [nTPM]":"304.7","Cell RNA - HEL [nTPM]":"486.6","Cell RNA - HeLa [nTPM]":"224.6","Cell RNA - Hep G2 [nTPM]":"445.3","Cell RNA - HHSteC [nTPM]":"222.7","Cell RNA - HL-60 [nTPM]":"529.7","Cell RNA - HMC-1 [nTPM]":"348.5","Cell RNA - HSkMC [nTPM]":"222.4","Cell RNA - hTCEpi [nTPM]":"99.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"437.5","Cell RNA - hTERT-HME1 [nTPM]":"258.9","Cell RNA - hTERT-RPE1 [nTPM]":"120.1","Cell RNA - HUVEC TERT2 [nTPM]":"295.7","Cell RNA - JURKAT [nTPM]":"419.6","Cell RNA - K-562 [nTPM]":"537.6","Cell RNA - Karpas-707 [nTPM]":"204.7","Cell RNA - LHCN-M2 [nTPM]":"357.0","Cell RNA - MCF7 [nTPM]":"483.0","Cell RNA - MOLT-4 [nTPM]":"446.2","Cell RNA - NB-4 [nTPM]":"475.5","Cell RNA - NTERA-2 [nTPM]":"649.0","Cell RNA - OE19 [nTPM]":"307.7","Cell RNA - PC-3 [nTPM]":"402.0","Cell RNA - REH [nTPM]":"677.0","Cell RNA - RH-30 [nTPM]":"535.9","Cell RNA - RPMI-8226 [nTPM]":"350.1","Cell RNA - RPTEC TERT1 [nTPM]":"344.0","Cell RNA - RT4 [nTPM]":"265.6","Cell RNA - SCLC-21H [nTPM]":"279.1","Cell RNA - SH-SY5Y [nTPM]":"478.9","Cell RNA - SiHa [nTPM]":"344.5","Cell RNA - SK-BR-3 [nTPM]":"255.7","Cell RNA - SK-MEL-30 [nTPM]":"267.8","Cell RNA - SuSa [nTPM]":"314.9","Cell RNA - T-47d [nTPM]":"291.8","Cell RNA - THP-1 [nTPM]":"597.5","Cell RNA - TIME [nTPM]":"276.3","Cell RNA - U-138 MG [nTPM]":"371.5","Cell RNA - U-2 OS [nTPM]":"365.5","Cell RNA - U-2197 [nTPM]":"242.1","Cell RNA - U-251 MG [nTPM]":"520.5","Cell RNA - U-266\/70 [nTPM]":"181.4","Cell RNA - U-266\/84 [nTPM]":"350.4","Cell RNA - U-698 [nTPM]":"779.0","Cell RNA - U-87 MG [nTPM]":"204.4","Cell RNA - U-937 [nTPM]":"364.2","Cell RNA - WM-115 [nTPM]":"460.9","Blood RNA - basophil [nTPM]":"12.3","Blood RNA - classical monocyte [nTPM]":"38.2","Blood RNA - eosinophil [nTPM]":"52.8","Blood RNA - gdT-cell [nTPM]":"53.6","Blood RNA - intermediate monocyte [nTPM]":"67.3","Blood RNA - MAIT T-cell [nTPM]":"49.9","Blood RNA - memory B-cell [nTPM]":"29.1","Blood RNA - memory CD4 T-cell [nTPM]":"36.5","Blood RNA - memory CD8 T-cell [nTPM]":"45.9","Blood RNA - myeloid DC [nTPM]":"41.7","Blood RNA - naive B-cell [nTPM]":"35.2","Blood RNA - naive CD4 T-cell [nTPM]":"40.3","Blood RNA - naive CD8 T-cell [nTPM]":"43.9","Blood RNA - neutrophil [nTPM]":"35.0","Blood RNA - NK-cell [nTPM]":"37.3","Blood RNA - non-classical monocyte [nTPM]":"59.3","Blood RNA - plasmacytoid DC [nTPM]":"50.3","Blood RNA - T-reg [nTPM]":"31.0","Blood RNA - total PBMC [nTPM]":"27.4","Brain RNA - amygdala [nTPM]":"43.6","Brain RNA - basal ganglia [nTPM]":"48.6","Brain RNA - cerebellum [nTPM]":"50.6","Brain RNA - cerebral cortex [nTPM]":"59.2","Brain RNA - hippocampal formation [nTPM]":"46.9","Brain RNA - hypothalamus [nTPM]":"48.6","Brain RNA - medulla oblongata [nTPM]":"44.3","Brain RNA - midbrain [nTPM]":"43.0","Brain RNA - pons [nTPM]":"46.9","Brain RNA - spinal cord [nTPM]":"45.7","Brain RNA - thalamus [nTPM]":"44.8","Brain RNA - white matter [nTPM]":"52.1","Single Cell Type RNA - Adipocytes [nTPM]":"414.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"102.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"121.2","Single Cell Type RNA - Astrocytes [nTPM]":"58.1","Single Cell Type RNA - B-cells [nTPM]":"470.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"144.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"345.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"201.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"507.6","Single Cell Type RNA - Bipolar cells [nTPM]":"272.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"209.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"223.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"102.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"112.9","Single Cell Type RNA - Club cells [nTPM]":"156.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"104.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"131.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"299.3","Single Cell Type RNA - dendritic cells [nTPM]":"488.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"266.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"68.4","Single Cell Type RNA - Ductal cells [nTPM]":"183.6","Single Cell Type RNA - Early spermatids [nTPM]":"130.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"201.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"366.1","Single Cell Type RNA - Endothelial cells [nTPM]":"278.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"212.1","Single Cell Type RNA - Erythroid cells [nTPM]":"188.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"75.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"154.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"398.5","Single Cell Type RNA - Fibroblasts [nTPM]":"309.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"222.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"309.7","Single Cell Type RNA - granulocytes [nTPM]":"229.7","Single Cell Type RNA - Granulosa cells [nTPM]":"445.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"174.2","Single Cell Type RNA - Hepatocytes [nTPM]":"59.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"208.5","Single Cell Type RNA - Horizontal cells [nTPM]":"201.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"85.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"229.5","Single Cell Type RNA - Ionocytes [nTPM]":"132.2","Single Cell Type RNA - Kupffer cells [nTPM]":"148.4","Single Cell Type RNA - Langerhans cells [nTPM]":"270.7","Single Cell Type RNA - Late spermatids [nTPM]":"51.2","Single Cell Type RNA - Leydig cells [nTPM]":"307.3","Single Cell Type RNA - Macrophages [nTPM]":"282.7","Single Cell Type RNA - Melanocytes [nTPM]":"165.4","Single Cell Type RNA - Microglial cells [nTPM]":"94.6","Single Cell Type RNA - monocytes [nTPM]":"185.4","Single Cell Type RNA - Muller glia cells [nTPM]":"230.8","Single Cell Type RNA - NK-cells [nTPM]":"341.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"117.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"122.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"175.7","Single Cell Type RNA - Paneth cells [nTPM]":"219.4","Single Cell Type RNA - Peritubular cells [nTPM]":"215.5","Single Cell Type RNA - Plasma cells [nTPM]":"266.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"245.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"205.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"69.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"115.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"266.3","Single Cell Type RNA - Sertoli cells [nTPM]":"164.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"584.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"344.2","Single Cell Type RNA - Spermatocytes [nTPM]":"221.0","Single Cell Type RNA - Spermatogonia [nTPM]":"237.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"443.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"154.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"295.1","Single Cell Type RNA - T-cells [nTPM]":"518.2","Single Cell Type RNA - Theca cells [nTPM]":"327.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"232.6","Single Cell Type RNA - Urothelial cells [nTPM]":"281.2"},{"Gene":"FXN","Gene synonym":["CyaY","FA","FARR","FRDA","X25"],"Ensembl":"ENSG00000165060","Gene description":"Frataxin","Uniprot":["Q16595"],"Chromosome":"9","Position":"69035751-69079076","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Heme biosynthesis","Ion transport","Iron storage","Iron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"69.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022164","HPA068304"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB022164":null,"HPA068304":"AB_2685970"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.3","Tissue RNA - adrenal gland [nTPM]":"20.1","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"9.2","Tissue RNA - bone marrow [nTPM]":"29.1","Tissue RNA - breast [nTPM]":"10.1","Tissue RNA - cerebellum [nTPM]":"9.7","Tissue RNA - cerebral cortex [nTPM]":"8.9","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"11.7","Tissue RNA - colon [nTPM]":"10.4","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"12.1","Tissue RNA - esophagus [nTPM]":"9.5","Tissue RNA - fallopian tube [nTPM]":"10.2","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"27.0","Tissue RNA - hippocampal formation [nTPM]":"9.0","Tissue RNA - hypothalamus [nTPM]":"10.4","Tissue RNA - kidney [nTPM]":"12.9","Tissue RNA - liver [nTPM]":"46.3","Tissue RNA - lung [nTPM]":"7.1","Tissue RNA - lymph node [nTPM]":"9.8","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"17.6","Tissue RNA - pancreas [nTPM]":"15.1","Tissue RNA - parathyroid gland [nTPM]":"22.2","Tissue RNA - pituitary gland [nTPM]":"8.1","Tissue RNA - placenta [nTPM]":"9.1","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"11.7","Tissue RNA - seminal vesicle [nTPM]":"13.6","Tissue RNA - skeletal muscle [nTPM]":"25.5","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"13.3","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"12.6","Tissue RNA - stomach 1 [nTPM]":"10.1","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"9.9","Tissue RNA - thymus [nTPM]":"5.4","Tissue RNA - thyroid gland [nTPM]":"10.4","Tissue RNA - tongue [nTPM]":"19.8","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"12.3","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"10.4","Cell RNA - A-431 [nTPM]":"27.0","Cell RNA - A549 [nTPM]":"22.1","Cell RNA - AF22 [nTPM]":"34.2","Cell RNA - AN3-CA [nTPM]":"17.0","Cell RNA - ASC diff [nTPM]":"15.7","Cell RNA - ASC TERT1 [nTPM]":"23.1","Cell RNA - BEWO [nTPM]":"34.3","Cell RNA - BJ [nTPM]":"18.6","Cell RNA - BJ hTERT+ [nTPM]":"16.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.2","Cell RNA - CACO-2 [nTPM]":"11.8","Cell RNA - CAPAN-2 [nTPM]":"16.6","Cell RNA - Daudi [nTPM]":"45.9","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"19.5","Cell RNA - GAMG [nTPM]":"28.8","Cell RNA - HaCaT [nTPM]":"28.6","Cell RNA - HAP1 [nTPM]":"41.8","Cell RNA - HBEC3-KT [nTPM]":"42.6","Cell RNA - HBF TERT88 [nTPM]":"34.9","Cell RNA - HDLM-2 [nTPM]":"53.9","Cell RNA - HEK 293 [nTPM]":"47.5","Cell RNA - HEL [nTPM]":"66.2","Cell RNA - HeLa [nTPM]":"14.1","Cell RNA - Hep G2 [nTPM]":"87.2","Cell RNA - HHSteC [nTPM]":"26.7","Cell RNA - HL-60 [nTPM]":"48.7","Cell RNA - HMC-1 [nTPM]":"27.7","Cell RNA - HSkMC [nTPM]":"25.7","Cell RNA - hTCEpi [nTPM]":"33.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.8","Cell RNA - hTERT-HME1 [nTPM]":"29.9","Cell RNA - hTERT-RPE1 [nTPM]":"9.6","Cell RNA - HUVEC TERT2 [nTPM]":"37.7","Cell RNA - JURKAT [nTPM]":"28.0","Cell RNA - K-562 [nTPM]":"50.3","Cell RNA - Karpas-707 [nTPM]":"43.9","Cell RNA - LHCN-M2 [nTPM]":"26.1","Cell RNA - MCF7 [nTPM]":"25.6","Cell RNA - MOLT-4 [nTPM]":"14.0","Cell RNA - NB-4 [nTPM]":"21.0","Cell RNA - NTERA-2 [nTPM]":"47.5","Cell RNA - OE19 [nTPM]":"53.1","Cell RNA - PC-3 [nTPM]":"42.8","Cell RNA - REH [nTPM]":"32.7","Cell RNA - RH-30 [nTPM]":"24.0","Cell RNA - RPMI-8226 [nTPM]":"32.0","Cell RNA - RPTEC TERT1 [nTPM]":"32.2","Cell RNA - RT4 [nTPM]":"21.5","Cell RNA - SCLC-21H [nTPM]":"26.9","Cell RNA - SH-SY5Y [nTPM]":"12.1","Cell RNA - SiHa [nTPM]":"19.2","Cell RNA - SK-BR-3 [nTPM]":"12.5","Cell RNA - SK-MEL-30 [nTPM]":"20.7","Cell RNA - SuSa [nTPM]":"24.3","Cell RNA - T-47d [nTPM]":"14.1","Cell RNA - THP-1 [nTPM]":"14.4","Cell RNA - TIME [nTPM]":"22.7","Cell RNA - U-138 MG [nTPM]":"18.0","Cell RNA - U-2 OS [nTPM]":"32.0","Cell RNA - U-2197 [nTPM]":"24.1","Cell RNA - U-251 MG [nTPM]":"27.6","Cell RNA - U-266\/70 [nTPM]":"11.6","Cell RNA - U-266\/84 [nTPM]":"11.4","Cell RNA - U-698 [nTPM]":"27.8","Cell RNA - U-87 MG [nTPM]":"8.5","Cell RNA - U-937 [nTPM]":"39.7","Cell RNA - WM-115 [nTPM]":"18.5","Blood RNA - basophil [nTPM]":"8.1","Blood RNA - classical monocyte [nTPM]":"39.9","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"48.6","Blood RNA - intermediate monocyte [nTPM]":"45.4","Blood RNA - MAIT T-cell [nTPM]":"37.5","Blood RNA - memory B-cell [nTPM]":"36.3","Blood RNA - memory CD4 T-cell [nTPM]":"48.0","Blood RNA - memory CD8 T-cell [nTPM]":"48.4","Blood RNA - myeloid DC [nTPM]":"42.8","Blood RNA - naive B-cell [nTPM]":"22.7","Blood RNA - naive CD4 T-cell [nTPM]":"61.6","Blood RNA - naive CD8 T-cell [nTPM]":"59.8","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"60.8","Blood RNA - non-classical monocyte [nTPM]":"36.2","Blood RNA - plasmacytoid DC [nTPM]":"33.2","Blood RNA - T-reg [nTPM]":"43.3","Blood RNA - total PBMC [nTPM]":"49.5","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"9.2","Brain RNA - cerebellum [nTPM]":"9.7","Brain RNA - cerebral cortex [nTPM]":"8.9","Brain RNA - hippocampal formation [nTPM]":"9.0","Brain RNA - hypothalamus [nTPM]":"10.4","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"9.9","Brain RNA - white matter [nTPM]":"10.4","Single Cell Type RNA - Adipocytes [nTPM]":"11.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"19.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.9","Single Cell Type RNA - dendritic cells [nTPM]":"14.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"17.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.5","Single Cell Type RNA - Endothelial cells [nTPM]":"16.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"56.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.3","Single Cell Type RNA - Fibroblasts [nTPM]":"14.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"15.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"69.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"22.1","Single Cell Type RNA - Langerhans cells [nTPM]":"16.1","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"15.8","Single Cell Type RNA - Macrophages [nTPM]":"13.9","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"18.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.6","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"42.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.8","Single Cell Type RNA - Spermatocytes [nTPM]":"5.1","Single Cell Type RNA - Spermatogonia [nTPM]":"32.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - T-cells [nTPM]":"17.1","Single Cell Type RNA - Theca cells [nTPM]":"27.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.5","Single Cell Type RNA - Urothelial cells [nTPM]":"14.1"},{"Gene":"FYCO1","Gene synonym":["FLJ13335","ZFYVE7"],"Ensembl":"ENSG00000163820","Gene description":"FYVE and coiled-coil domain autophagy adaptor 1","Uniprot":["Q9BQS8"],"Chromosome":"3","Position":"45917899-45995824","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"263.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"89.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035526","HPA057966"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035526":"AB_10672867","HPA057966":"AB_2683567"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.33e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.7","Tissue RNA - adrenal gland [nTPM]":"13.0","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"9.7","Tissue RNA - basal ganglia [nTPM]":"12.0","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"9.4","Tissue RNA - cervix [nTPM]":"23.1","Tissue RNA - choroid plexus [nTPM]":"11.3","Tissue RNA - colon [nTPM]":"42.0","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"25.6","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"21.3","Tissue RNA - fallopian tube [nTPM]":"15.4","Tissue RNA - gallbladder [nTPM]":"18.7","Tissue RNA - heart muscle [nTPM]":"66.8","Tissue RNA - hippocampal formation [nTPM]":"8.6","Tissue RNA - hypothalamus [nTPM]":"10.3","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"10.8","Tissue RNA - lung [nTPM]":"14.7","Tissue RNA - lymph node [nTPM]":"8.6","Tissue RNA - medulla oblongata [nTPM]":"15.5","Tissue RNA - midbrain [nTPM]":"10.8","Tissue RNA - ovary [nTPM]":"23.1","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"20.3","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"19.3","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"33.0","Tissue RNA - salivary gland [nTPM]":"14.9","Tissue RNA - seminal vesicle [nTPM]":"22.9","Tissue RNA - skeletal muscle [nTPM]":"263.3","Tissue RNA - skin 1 [nTPM]":"19.3","Tissue RNA - small intestine [nTPM]":"14.4","Tissue RNA - smooth muscle [nTPM]":"28.2","Tissue RNA - spinal cord [nTPM]":"15.1","Tissue RNA - spleen [nTPM]":"10.2","Tissue RNA - stomach 1 [nTPM]":"20.4","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"11.9","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"16.5","Tissue RNA - tongue [nTPM]":"104.6","Tissue RNA - tonsil [nTPM]":"8.2","Tissue RNA - urinary bladder [nTPM]":"39.6","Tissue RNA - vagina [nTPM]":"16.9","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"10.8","Cell RNA - A549 [nTPM]":"10.3","Cell RNA - AF22 [nTPM]":"3.0","Cell RNA - AN3-CA [nTPM]":"13.0","Cell RNA - ASC diff [nTPM]":"27.9","Cell RNA - ASC TERT1 [nTPM]":"21.8","Cell RNA - BEWO [nTPM]":"4.9","Cell RNA - BJ [nTPM]":"10.2","Cell RNA - BJ hTERT+ [nTPM]":"23.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.6","Cell RNA - CACO-2 [nTPM]":"5.6","Cell RNA - CAPAN-2 [nTPM]":"9.3","Cell RNA - Daudi [nTPM]":"7.9","Cell RNA - EFO-21 [nTPM]":"5.6","Cell RNA - fHDF\/TERT166 [nTPM]":"14.2","Cell RNA - GAMG [nTPM]":"12.7","Cell RNA - HaCaT [nTPM]":"7.9","Cell RNA - HAP1 [nTPM]":"8.5","Cell RNA - HBEC3-KT [nTPM]":"17.0","Cell RNA - HBF TERT88 [nTPM]":"15.7","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"9.0","Cell RNA - HEL [nTPM]":"11.4","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"6.3","Cell RNA - HHSteC [nTPM]":"19.0","Cell RNA - HL-60 [nTPM]":"8.8","Cell RNA - HMC-1 [nTPM]":"7.9","Cell RNA - HSkMC [nTPM]":"24.3","Cell RNA - hTCEpi [nTPM]":"16.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.1","Cell RNA - hTERT-HME1 [nTPM]":"20.5","Cell RNA - hTERT-RPE1 [nTPM]":"20.3","Cell RNA - HUVEC TERT2 [nTPM]":"26.7","Cell RNA - JURKAT [nTPM]":"13.4","Cell RNA - K-562 [nTPM]":"7.4","Cell RNA - Karpas-707 [nTPM]":"11.3","Cell RNA - LHCN-M2 [nTPM]":"9.5","Cell RNA - MCF7 [nTPM]":"6.7","Cell RNA - MOLT-4 [nTPM]":"9.0","Cell RNA - NB-4 [nTPM]":"5.5","Cell RNA - NTERA-2 [nTPM]":"4.5","Cell RNA - OE19 [nTPM]":"8.8","Cell RNA - PC-3 [nTPM]":"9.8","Cell RNA - REH [nTPM]":"3.1","Cell RNA - RH-30 [nTPM]":"8.3","Cell RNA - RPMI-8226 [nTPM]":"4.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.9","Cell RNA - RT4 [nTPM]":"37.2","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"3.4","Cell RNA - SiHa [nTPM]":"6.4","Cell RNA - SK-BR-3 [nTPM]":"20.0","Cell RNA - SK-MEL-30 [nTPM]":"17.6","Cell RNA - SuSa [nTPM]":"4.4","Cell RNA - T-47d [nTPM]":"9.7","Cell RNA - THP-1 [nTPM]":"5.7","Cell RNA - TIME [nTPM]":"20.8","Cell RNA - U-138 MG [nTPM]":"5.0","Cell RNA - U-2 OS [nTPM]":"5.9","Cell RNA - U-2197 [nTPM]":"17.0","Cell RNA - U-251 MG [nTPM]":"5.7","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"4.4","Cell RNA - U-698 [nTPM]":"2.7","Cell RNA - U-87 MG [nTPM]":"17.2","Cell RNA - U-937 [nTPM]":"11.1","Cell RNA - WM-115 [nTPM]":"9.6","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"12.0","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"9.4","Brain RNA - hippocampal formation [nTPM]":"8.6","Brain RNA - hypothalamus [nTPM]":"10.3","Brain RNA - medulla oblongata [nTPM]":"15.5","Brain RNA - midbrain [nTPM]":"10.8","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"15.1","Brain RNA - thalamus [nTPM]":"11.9","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"9.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.7","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"4.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"11.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"89.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.3","Single Cell Type RNA - dendritic cells [nTPM]":"8.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"9.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"14.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"14.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"9.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"4.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"3.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"12.7","Single Cell Type RNA - Theca cells [nTPM]":"6.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.2","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"FZD4","Gene synonym":["CD344","EVR1"],"Ensembl":"ENSG00000174804","Gene description":"Frizzled class receptor 4","Uniprot":["Q9ULV1"],"Chromosome":"11","Position":"86945679-86955395","Protein class":["CD markers","Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"120.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"83.0","Collecting duct cells":"36.8","Endothelial cells":"51.2","Hepatic stellate cells":"99.6","Sertoli cells":"32.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"22.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"63.6","Hep G2":"85.2","HSkMC":"46.0","HUVEC TERT2":"93.6","TIME":"46.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042328","HPA074833"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA042328":"AB_10962494","HPA074833":"AB_2686716"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"120.1","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"5.8","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"55.6","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"7.8","Tissue RNA - colon [nTPM]":"14.9","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"12.2","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"6.5","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"27.4","Tissue RNA - hippocampal formation [nTPM]":"5.6","Tissue RNA - hypothalamus [nTPM]":"5.9","Tissue RNA - kidney [nTPM]":"27.1","Tissue RNA - liver [nTPM]":"14.6","Tissue RNA - lung [nTPM]":"32.9","Tissue RNA - lymph node [nTPM]":"6.2","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"12.9","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"8.7","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"7.0","Tissue RNA - prostate [nTPM]":"12.5","Tissue RNA - rectum [nTPM]":"6.3","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"12.2","Tissue RNA - seminal vesicle [nTPM]":"30.2","Tissue RNA - skeletal muscle [nTPM]":"31.5","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"8.8","Tissue RNA - smooth muscle [nTPM]":"13.4","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"14.1","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"8.5","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"18.1","Tissue RNA - tongue [nTPM]":"40.6","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"10.5","Tissue RNA - vagina [nTPM]":"9.5","Tissue RNA - white matter [nTPM]":"5.9","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"5.2","Cell RNA - ASC diff [nTPM]":"63.6","Cell RNA - ASC TERT1 [nTPM]":"16.5","Cell RNA - BEWO [nTPM]":"3.7","Cell RNA - BJ [nTPM]":"8.4","Cell RNA - BJ hTERT+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.3","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"2.6","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"2.8","Cell RNA - HAP1 [nTPM]":"3.1","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"2.5","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"85.2","Cell RNA - HHSteC [nTPM]":"18.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"46.0","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.8","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"7.5","Cell RNA - HUVEC TERT2 [nTPM]":"93.6","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"3.9","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"2.2","Cell RNA - MCF7 [nTPM]":"2.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"7.5","Cell RNA - PC-3 [nTPM]":"18.8","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"4.8","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"9.0","Cell RNA - RT4 [nTPM]":"13.7","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"3.5","Cell RNA - SK-BR-3 [nTPM]":"1.0","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"5.6","Cell RNA - T-47d [nTPM]":"12.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"46.3","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"5.1","Cell RNA - U-2197 [nTPM]":"9.2","Cell RNA - U-251 MG [nTPM]":"1.7","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"1.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"5.6","Brain RNA - hypothalamus [nTPM]":"5.9","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"7.0","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"8.5","Brain RNA - white matter [nTPM]":"5.9","Single Cell Type RNA - Adipocytes [nTPM]":"83.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"2.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.7","Single Cell Type RNA - Endothelial cells [nTPM]":"51.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"17.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"99.6","Single Cell Type RNA - Hepatocytes [nTPM]":"14.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"16.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"GAB1","Gene synonym":["DFNB26"],"Ensembl":"ENSG00000109458","Gene description":"GRB2 associated binding protein 1","Uniprot":["Q13480"],"Chromosome":"4","Position":"143336762-143474568","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"114.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"162.7","Microglial cells":"192.0","Oligodendrocyte precursor cells":"288.0","Oligodendrocytes":"1013.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"5.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"REH":"74.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034333","HPA066404"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoli fibrillar center","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB034333":"AB_2107855","HPA066404":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"23.3","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"69.9","Tissue RNA - bone marrow [nTPM]":"11.5","Tissue RNA - breast [nTPM]":"9.9","Tissue RNA - cerebellum [nTPM]":"35.5","Tissue RNA - cerebral cortex [nTPM]":"30.0","Tissue RNA - cervix [nTPM]":"10.6","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"19.7","Tissue RNA - duodenum [nTPM]":"12.1","Tissue RNA - endometrium 1 [nTPM]":"18.1","Tissue RNA - epididymis [nTPM]":"14.2","Tissue RNA - esophagus [nTPM]":"20.4","Tissue RNA - fallopian tube [nTPM]":"9.2","Tissue RNA - gallbladder [nTPM]":"12.5","Tissue RNA - heart muscle [nTPM]":"30.5","Tissue RNA - hippocampal formation [nTPM]":"20.4","Tissue RNA - hypothalamus [nTPM]":"34.6","Tissue RNA - kidney [nTPM]":"13.9","Tissue RNA - liver [nTPM]":"9.1","Tissue RNA - lung [nTPM]":"17.9","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"57.3","Tissue RNA - midbrain [nTPM]":"45.4","Tissue RNA - ovary [nTPM]":"19.5","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"11.3","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"21.0","Tissue RNA - pons [nTPM]":"47.9","Tissue RNA - prostate [nTPM]":"8.5","Tissue RNA - rectum [nTPM]":"22.8","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"8.9","Tissue RNA - seminal vesicle [nTPM]":"14.7","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"10.7","Tissue RNA - small intestine [nTPM]":"12.3","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"26.4","Tissue RNA - spleen [nTPM]":"7.5","Tissue RNA - stomach 1 [nTPM]":"11.3","Tissue RNA - testis [nTPM]":"9.2","Tissue RNA - thalamus [nTPM]":"45.7","Tissue RNA - thymus [nTPM]":"5.4","Tissue RNA - thyroid gland [nTPM]":"7.5","Tissue RNA - tongue [nTPM]":"16.5","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"7.1","Tissue RNA - vagina [nTPM]":"9.7","Tissue RNA - white matter [nTPM]":"114.8","Cell RNA - A-431 [nTPM]":"6.7","Cell RNA - A549 [nTPM]":"1.4","Cell RNA - AF22 [nTPM]":"16.7","Cell RNA - AN3-CA [nTPM]":"12.1","Cell RNA - ASC diff [nTPM]":"8.3","Cell RNA - ASC TERT1 [nTPM]":"7.9","Cell RNA - BEWO [nTPM]":"22.0","Cell RNA - BJ [nTPM]":"4.6","Cell RNA - BJ hTERT+ [nTPM]":"15.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.4","Cell RNA - CACO-2 [nTPM]":"12.8","Cell RNA - CAPAN-2 [nTPM]":"11.2","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"6.5","Cell RNA - GAMG [nTPM]":"3.7","Cell RNA - HaCaT [nTPM]":"3.8","Cell RNA - HAP1 [nTPM]":"16.2","Cell RNA - HBEC3-KT [nTPM]":"5.3","Cell RNA - HBF TERT88 [nTPM]":"6.2","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"3.9","Cell RNA - HEL [nTPM]":"12.2","Cell RNA - HeLa [nTPM]":"3.7","Cell RNA - Hep G2 [nTPM]":"6.1","Cell RNA - HHSteC [nTPM]":"5.7","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"9.7","Cell RNA - hTCEpi [nTPM]":"9.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.6","Cell RNA - hTERT-HME1 [nTPM]":"4.3","Cell RNA - hTERT-RPE1 [nTPM]":"11.5","Cell RNA - HUVEC TERT2 [nTPM]":"7.2","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"4.1","Cell RNA - Karpas-707 [nTPM]":"21.7","Cell RNA - LHCN-M2 [nTPM]":"3.8","Cell RNA - MCF7 [nTPM]":"9.7","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.8","Cell RNA - OE19 [nTPM]":"3.5","Cell RNA - PC-3 [nTPM]":"5.3","Cell RNA - REH [nTPM]":"74.6","Cell RNA - RH-30 [nTPM]":"8.2","Cell RNA - RPMI-8226 [nTPM]":"8.8","Cell RNA - RPTEC TERT1 [nTPM]":"8.4","Cell RNA - RT4 [nTPM]":"8.0","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"3.1","Cell RNA - SK-BR-3 [nTPM]":"13.3","Cell RNA - SK-MEL-30 [nTPM]":"5.6","Cell RNA - SuSa [nTPM]":"11.2","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"1.6","Cell RNA - TIME [nTPM]":"5.5","Cell RNA - U-138 MG [nTPM]":"6.9","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"3.4","Cell RNA - U-251 MG [nTPM]":"3.5","Cell RNA - U-266\/70 [nTPM]":"34.6","Cell RNA - U-266\/84 [nTPM]":"18.2","Cell RNA - U-698 [nTPM]":"26.3","Cell RNA - U-87 MG [nTPM]":"4.7","Cell RNA - U-937 [nTPM]":"4.8","Cell RNA - WM-115 [nTPM]":"5.7","Blood RNA - basophil [nTPM]":"4.1","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"5.0","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"23.3","Brain RNA - basal ganglia [nTPM]":"69.9","Brain RNA - cerebellum [nTPM]":"35.5","Brain RNA - cerebral cortex [nTPM]":"30.0","Brain RNA - hippocampal formation [nTPM]":"20.4","Brain RNA - hypothalamus [nTPM]":"34.6","Brain RNA - medulla oblongata [nTPM]":"57.3","Brain RNA - midbrain [nTPM]":"45.4","Brain RNA - pons [nTPM]":"47.9","Brain RNA - spinal cord [nTPM]":"26.4","Brain RNA - thalamus [nTPM]":"45.7","Brain RNA - white matter [nTPM]":"114.8","Single Cell Type RNA - Adipocytes [nTPM]":"13.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.0","Single Cell Type RNA - Astrocytes [nTPM]":"89.5","Single Cell Type RNA - B-cells [nTPM]":"13.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"5.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.5","Single Cell Type RNA - dendritic cells [nTPM]":"10.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.3","Single Cell Type RNA - Endothelial cells [nTPM]":"16.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.2","Single Cell Type RNA - Erythroid cells [nTPM]":"40.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"162.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.6","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.6","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"9.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"62.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.6","Single Cell Type RNA - Langerhans cells [nTPM]":"10.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"8.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"192.0","Single Cell Type RNA - monocytes [nTPM]":"5.6","Single Cell Type RNA - Muller glia cells [nTPM]":"15.4","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"288.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1013.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.9","Single Cell Type RNA - Paneth cells [nTPM]":"10.7","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"94.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.0","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"4.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.6","Single Cell Type RNA - Urothelial cells [nTPM]":"13.5"},{"Gene":"GABBR2","Gene synonym":["GABABR2","GPR51","GPRC3B","HG20"],"Ensembl":"ENSG00000136928","Gene description":"Gamma-aminobutyric acid type B receptor subunit 2","Uniprot":["O75899"],"Chromosome":"9","Position":"98288109-98708935","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"90.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"386.5","Inhibitory neurons":"395.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"glioma":"7.2","thyroid cancer":"11.6","urothelial cancer":"3.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"14.6","fHDF\/TERT166":"7.3","HUVEC TERT2":"29.5","U-138 MG":"11.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013820","HPA031684","CAB079065"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079065":null,"HPA013820":"AB_1849364","HPA031684":"AB_2673993"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"26.0","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"40.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"10.6","Tissue RNA - cerebral cortex [nTPM]":"90.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"39.9","Tissue RNA - hypothalamus [nTPM]":"18.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"12.7","Tissue RNA - midbrain [nTPM]":"19.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"2.8","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"8.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"39.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"36.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"14.6","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.5","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"7.3","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"29.5","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"3.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"11.5","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"26.0","Brain RNA - basal ganglia [nTPM]":"40.8","Brain RNA - cerebellum [nTPM]":"10.6","Brain RNA - cerebral cortex [nTPM]":"90.4","Brain RNA - hippocampal formation [nTPM]":"39.9","Brain RNA - hypothalamus [nTPM]":"18.0","Brain RNA - medulla oblongata [nTPM]":"12.7","Brain RNA - midbrain [nTPM]":"19.6","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"8.3","Brain RNA - thalamus [nTPM]":"39.5","Brain RNA - white matter [nTPM]":"36.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"86.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"90.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"386.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"395.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"34.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GABRA1","Gene synonym":["EJM5"],"Ensembl":"ENSG00000022355","Gene description":"Gamma-aminobutyric acid type A receptor subunit alpha1","Uniprot":["P14867"],"Chromosome":"5","Position":"161847063-161899981","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"30","RNA tissue specific nTPM":{"brain":"55.1","retina":"17.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Bipolar cells":"198.0","Excitatory neurons":"220.5","Inhibitory neurons":"215.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022502","HPA029363","HPA055746"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB022502":null,"HPA029363":null,"HPA055746":"AB_2682904"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"11.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"24.8","Tissue RNA - cerebral cortex [nTPM]":"55.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"21.7","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"17.8","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"14.3","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"24.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"11.1","Brain RNA - cerebellum [nTPM]":"24.8","Brain RNA - cerebral cortex [nTPM]":"55.1","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"21.7","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"14.3","Brain RNA - white matter [nTPM]":"24.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"198.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"220.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"215.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GABRA2","Gene synonym":[],"Ensembl":"ENSG00000151834","Gene description":"Gamma-aminobutyric acid type A receptor subunit alpha2","Uniprot":["P47869"],"Chromosome":"4","Position":"46243548-46475230","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"31.5","epididymis":"8.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"425.4","Excitatory neurons":"156.2","Inhibitory neurons":"111.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"0.6","glioma":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"U-2 OS":"4.2","U-87 MG":"2.1","WM-115":"2.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029363","CAB079061"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB079061":null,"HPA029363":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"20.2","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"29.9","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"31.5","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.0","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"8.8","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"29.4","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"6.0","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"13.8","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"8.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"2.1","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"20.2","Brain RNA - basal ganglia [nTPM]":"29.9","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"31.5","Brain RNA - hippocampal formation [nTPM]":"29.4","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"13.8","Brain RNA - white matter [nTPM]":"8.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"425.4","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"9.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"156.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"111.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"17.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GABRA5","Gene synonym":[],"Ensembl":"ENSG00000186297","Gene description":"Gamma-aminobutyric acid type A receptor subunit alpha5","Uniprot":["P31644"],"Chromosome":"15","Position":"26866911-26949208","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"111.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"27.6","Inhibitory neurons":"14.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.8"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"52.0","basal ganglia":"73.5","cerebral cortex":"98.6","hippocampal formation":"111.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"A549":"35.3","HAP1":"12.0","NTERA-2":"16.2","U-2 OS":"13.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029363","HPA077031","CAB079022"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB079022":null,"HPA029363":null,"HPA077031":"AB_2686825"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"52.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"73.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"98.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"111.0","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"12.0","Tissue RNA - thymus [nTPM]":"9.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"19.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"35.3","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"12.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"16.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"1.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"13.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"52.0","Brain RNA - basal ganglia [nTPM]":"73.5","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"98.6","Brain RNA - hippocampal formation [nTPM]":"111.0","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"12.0","Brain RNA - white matter [nTPM]":"19.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GABRB1","Gene synonym":[],"Ensembl":"ENSG00000163288","Gene description":"Gamma-aminobutyric acid type A receptor subunit beta1","Uniprot":["P18505"],"Chromosome":"4","Position":"46993723-47426447","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"26.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Astrocytes":"926.2","Excitatory neurons":"440.3","Inhibitory neurons":"507.4","Oligodendrocyte precursor cells":"266.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"REH":"7.1","U-87 MG":"2.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-3"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"19.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"24.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"26.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"3.6","Tissue RNA - hippocampal formation [nTPM]":"26.2","Tissue RNA - hypothalamus [nTPM]":"24.6","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"26.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"7.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"19.1","Brain RNA - basal ganglia [nTPM]":"24.8","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"26.3","Brain RNA - hippocampal formation [nTPM]":"26.2","Brain RNA - hypothalamus [nTPM]":"24.6","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"26.1","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"926.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"440.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"507.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"32.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"266.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GABRB2","Gene synonym":[],"Ensembl":"ENSG00000145864","Gene description":"Gamma-aminobutyric acid type A receptor subunit beta2","Uniprot":["P47870"],"Chromosome":"5","Position":"161288429-161549044","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"71.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Excitatory neurons":"570.3","Inhibitory neurons":"780.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"thyroid cancer":"10.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebellum":"63.2","cerebral cortex":"71.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"SCLC-21H":"22.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001964","HPA067632"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001964":null,"HPA067632":"AB_2685874"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"5.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"63.2","Tissue RNA - cerebral cortex [nTPM]":"71.7","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"9.2","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"1.8","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"9.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"1.7","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"22.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"2.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"5.8","Brain RNA - cerebellum [nTPM]":"63.2","Brain RNA - cerebral cortex [nTPM]":"71.7","Brain RNA - hippocampal formation [nTPM]":"9.2","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"9.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"19.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"570.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"780.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"1.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GABRB3","Gene synonym":[],"Ensembl":"ENSG00000166206","Gene description":"Gamma-aminobutyric acid type A receptor subunit beta3","Uniprot":["P28472"],"Chromosome":"15","Position":"26543546-26939539","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"29.5","retina":"31.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"152.4","Excitatory neurons":"519.6","Inhibitory neurons":"258.7","Oligodendrocyte precursor cells":"139.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"68.5","HAP1":"27.9","NTERA-2":"48.3","OE19":"21.6","SCLC-21H":"44.2","U-2 OS":"18.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"5.5","Tissue RNA - amygdala [nTPM]":"16.6","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"24.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"29.5","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.2","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"13.6","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"28.0","Tissue RNA - hypothalamus [nTPM]":"18.0","Tissue RNA - kidney [nTPM]":"7.3","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"15.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"31.9","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"5.7","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"11.6","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"8.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"13.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"68.5","Cell RNA - AF22 [nTPM]":"10.7","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.6","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"27.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"5.4","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"14.8","Cell RNA - K-562 [nTPM]":"2.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"4.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"48.3","Cell RNA - OE19 [nTPM]":"21.6","Cell RNA - PC-3 [nTPM]":"3.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"44.2","Cell RNA - SH-SY5Y [nTPM]":"16.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"18.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"1.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"16.6","Brain RNA - basal ganglia [nTPM]":"24.3","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"29.5","Brain RNA - hippocampal formation [nTPM]":"28.0","Brain RNA - hypothalamus [nTPM]":"18.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"11.6","Brain RNA - white matter [nTPM]":"13.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.6","Single Cell Type RNA - Astrocytes [nTPM]":"33.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"152.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"1.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.6","Single Cell Type RNA - Early spermatids [nTPM]":"10.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"519.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"75.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"258.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"7.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"139.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"8.6","Single Cell Type RNA - Spermatogonia [nTPM]":"29.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"GABRD","Gene synonym":[],"Ensembl":"ENSG00000187730","Gene description":"Gamma-aminobutyric acid type A receptor subunit delta","Uniprot":["O14764"],"Chromosome":"1","Position":"2019329-2030758","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"49.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"14.7","Excitatory neurons":"30.0","Horizontal cells":"13.5","Inhibitory neurons":"37.4","Spermatogonia":"11.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"1.4","HMC-1":"1.2","MCF7":"4.4","NB-4":"2.7","SH-SY5Y":"1.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044371"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA044371":"AB_2678916"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-8"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.12e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"12.8","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"16.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"49.6","Tissue RNA - cerebral cortex [nTPM]":"40.5","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"14.3","Tissue RNA - midbrain [nTPM]":"18.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"20.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"29.7","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"14.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.7","Cell RNA - NTERA-2 [nTPM]":"1.0","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"12.8","Brain RNA - basal ganglia [nTPM]":"16.9","Brain RNA - cerebellum [nTPM]":"49.6","Brain RNA - cerebral cortex [nTPM]":"40.5","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"14.3","Brain RNA - midbrain [nTPM]":"18.1","Brain RNA - pons [nTPM]":"20.2","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"29.7","Brain RNA - white matter [nTPM]":"14.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.6","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"14.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"11.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GABRG2","Gene synonym":[],"Ensembl":"ENSG00000113327","Gene description":"Gamma-aminobutyric acid type A receptor subunit gamma2","Uniprot":["P18507"],"Chromosome":"5","Position":"162000057-162162977","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"20.0","retina":"10.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"119.0","Excitatory neurons":"239.9","Inhibitory neurons":"167.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"4.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1.6","granulocytes":"4.5","T-cells":"1.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"10.3","Karpas-707":"10.2","RPMI-8226":"13.4","SuSa":"13.0","U-266\/70":"20.1","U-266\/84":"18.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB079060"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079060":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"4.7","Tissue RNA - amygdala [nTPM]":"7.9","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"9.0","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"20.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"10.7","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"10.9","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"1.7","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"2.3","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"1.9","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"10.3","Cell RNA - CAPAN-2 [nTPM]":"5.5","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"1.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"10.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"7.4","Cell RNA - OE19 [nTPM]":"3.1","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"13.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.1","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"4.1","Cell RNA - SuSa [nTPM]":"13.0","Cell RNA - T-47d [nTPM]":"6.7","Cell RNA - THP-1 [nTPM]":"6.9","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"20.1","Cell RNA - U-266\/84 [nTPM]":"18.7","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"4.5","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"7.9","Brain RNA - basal ganglia [nTPM]":"9.0","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"20.0","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"10.7","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.5","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"119.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"239.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"167.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GAD1","Gene synonym":["GAD"],"Ensembl":"ENSG00000128683","Gene description":"Glutamate decarboxylase 1","Uniprot":["Q99259"],"Chromosome":"2","Position":"170813213-170861151","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Neurotransmitter biosynthesis"],"Molecular function":["Decarboxylase","Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"98.5","parathyroid gland":"46.3","retina":"29.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Inhibitory neurons":"392.8","Oligodendrocyte precursor cells":"146.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"20.1","HEL":"64.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"olfactory bulb":"547.6"},"Antibody":["CAB004415","HPA048871","HPA058412","CAB078176"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004415":"AB_627650","CAB078176":"AB_2665792","HPA048871":null,"HPA058412":"AB_2683710"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.31e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"29.9","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"15.5","Tissue RNA - cerebral cortex [nTPM]":"33.0","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"17.1","Tissue RNA - hypothalamus [nTPM]":"98.5","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"41.6","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"46.3","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"17.6","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"29.7","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"31.1","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"14.2","Cell RNA - A-431 [nTPM]":"18.2","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"7.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"6.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"20.1","Cell RNA - HAP1 [nTPM]":"2.3","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"2.8","Cell RNA - HEK 293 [nTPM]":"13.4","Cell RNA - HEL [nTPM]":"64.5","Cell RNA - HeLa [nTPM]":"6.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"5.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"2.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"17.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"9.7","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"4.6","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"8.5","Cell RNA - RT4 [nTPM]":"9.4","Cell RNA - SCLC-21H [nTPM]":"6.7","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"12.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"12.0","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"2.4","Cell RNA - U-251 MG [nTPM]":"7.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"11.5","Cell RNA - U-937 [nTPM]":"3.2","Cell RNA - WM-115 [nTPM]":"16.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"29.9","Brain RNA - cerebellum [nTPM]":"15.5","Brain RNA - cerebral cortex [nTPM]":"33.0","Brain RNA - hippocampal formation [nTPM]":"17.1","Brain RNA - hypothalamus [nTPM]":"98.5","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"41.6","Brain RNA - pons [nTPM]":"17.6","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"31.1","Brain RNA - white matter [nTPM]":"14.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"32.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.5","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"392.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"146.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"GAL","Gene synonym":["GAL-GMAP","GALN","GLNN","GMAP"],"Ensembl":"ENSG00000069482","Gene description":"Galanin and GMAP prepropeptide","Uniprot":["P22466"],"Chromosome":"11","Position":"68683779-68691175","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hormone","Neuropeptide"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"brain":"645.9","pituitary gland":"885.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal prostatic cells":"22.2","Ductal cells":"38.9","Endometrial ciliated cells":"64.2","Endometrial stromal cells":"50.8","Exocrine glandular cells":"52.1","Extravillous trophoblasts":"48.7","Glandular and luminal cells":"26.4","Pancreatic endocrine cells":"39.5","Prostatic glandular cells":"82.5","Urothelial cells":"24.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"22.2"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"13","RNA brain regional specific nTPM":{"hypothalamus":"645.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"267.2","HEK 293":"119.3","K-562":"139.5","NB-4":"493.5","SH-SY5Y":"189.6"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"82.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049864","CAB079779"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":60000,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB079779":null,"HPA049864":"AB_2680922"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.17e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.2","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"17.6","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"645.9","Tissue RNA - kidney [nTPM]":"1.5","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"48.5","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"885.8","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"33.3","Tissue RNA - small intestine [nTPM]":"4.1","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"9.7","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"19.5","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"11.0","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"24.0","Cell RNA - BJ [nTPM]":"36.7","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"267.2","Cell RNA - CAPAN-2 [nTPM]":"9.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"119.3","Cell RNA - HEL [nTPM]":"6.4","Cell RNA - HeLa [nTPM]":"74.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"4.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"6.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"139.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"77.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"493.5","Cell RNA - NTERA-2 [nTPM]":"60.3","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"23.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"51.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.6","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"49.8","Cell RNA - SH-SY5Y [nTPM]":"189.6","Cell RNA - SiHa [nTPM]":"25.8","Cell RNA - SK-BR-3 [nTPM]":"1.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"26.8","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"57.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"2.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"645.9","Brain RNA - medulla oblongata [nTPM]":"48.5","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"19.5","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"38.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"64.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"50.8","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.4","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"82.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"10.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"24.3"},{"Gene":"GAN","Gene synonym":["GAN1","GIG","KLHL16"],"Ensembl":"ENSG00000261609","Gene description":"Gigaxonin","Uniprot":["Q9H2C0"],"Chromosome":"16","Position":"81314944-81390809","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"24.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"130.4","Urothelial cells":"188.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"10.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011825","HPA049473"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB011825":"AB_732515","HPA049473":"AB_2680782"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"5.7","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"2.4","Tissue RNA - cerebellum [nTPM]":"6.6","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"2.6","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"8.8","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"9.3","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"24.8","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"8.7","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"1.8","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"8.7","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"2.0","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"1.9","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"10.4","Cell RNA - BJ [nTPM]":"1.2","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"1.8","Cell RNA - Daudi [nTPM]":"2.5","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"1.6","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"3.1","Cell RNA - HAP1 [nTPM]":"2.7","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"1.8","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"2.2","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"2.0","Cell RNA - HL-60 [nTPM]":"2.1","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.3","Cell RNA - hTERT-HME1 [nTPM]":"3.5","Cell RNA - hTERT-RPE1 [nTPM]":"1.1","Cell RNA - HUVEC TERT2 [nTPM]":"1.7","Cell RNA - JURKAT [nTPM]":"2.1","Cell RNA - K-562 [nTPM]":"2.8","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"9.1","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"2.9","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"2.2","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"3.7","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"5.0","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"4.3","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"3.6","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"2.5","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"2.1","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"1.9","Cell RNA - U-266\/70 [nTPM]":"2.2","Cell RNA - U-266\/84 [nTPM]":"2.7","Cell RNA - U-698 [nTPM]":"5.8","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"2.4","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"5.7","Brain RNA - cerebellum [nTPM]":"6.6","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"8.8","Brain RNA - medulla oblongata [nTPM]":"9.3","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"8.7","Brain RNA - thalamus [nTPM]":"8.7","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"12.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"69.5","Single Cell Type RNA - B-cells [nTPM]":"9.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"91.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"66.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"28.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"29.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"89.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.3","Single Cell Type RNA - dendritic cells [nTPM]":"17.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.3","Single Cell Type RNA - Endothelial cells [nTPM]":"14.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"12.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.4","Single Cell Type RNA - Fibroblasts [nTPM]":"14.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.1","Single Cell Type RNA - Hepatocytes [nTPM]":"6.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.6","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.8","Single Cell Type RNA - Langerhans cells [nTPM]":"30.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"8.6","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"7.5","Single Cell Type RNA - Muller glia cells [nTPM]":"14.0","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.6","Single Cell Type RNA - Paneth cells [nTPM]":"16.8","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"11.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"75.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.6","Single Cell Type RNA - Spermatocytes [nTPM]":"11.9","Single Cell Type RNA - Spermatogonia [nTPM]":"16.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"67.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"130.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.3","Single Cell Type RNA - T-cells [nTPM]":"16.1","Single Cell Type RNA - Theca cells [nTPM]":"5.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.6","Single Cell Type RNA - Urothelial cells [nTPM]":"188.7"},{"Gene":"GARS1","Gene synonym":["CMT2D","DSMAV","GARS","GlyRS","SMAD1"],"Ensembl":"ENSG00000106105","Gene description":"Glycyl-tRNA synthetase 1","Uniprot":["P41250"],"Chromosome":"7","Position":"30580533-30634033","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Hydrolase","Ligase","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"34.1","Cytotrophoblasts":"47.0","Extravillous trophoblasts":"70.0","Hofbauer cells":"44.3","Syncytiotrophoblasts":"39.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017896","HPA019097"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"560000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017896":"AB_1849478","HPA019097":"AB_1849480"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.48e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.95e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.04e-5"},"Tissue RNA - adipose tissue [nTPM]":"34.2","Tissue RNA - adrenal gland [nTPM]":"31.0","Tissue RNA - amygdala [nTPM]":"33.3","Tissue RNA - appendix [nTPM]":"43.3","Tissue RNA - basal ganglia [nTPM]":"36.5","Tissue RNA - bone marrow [nTPM]":"32.0","Tissue RNA - breast [nTPM]":"31.7","Tissue RNA - cerebellum [nTPM]":"34.2","Tissue RNA - cerebral cortex [nTPM]":"46.2","Tissue RNA - cervix [nTPM]":"32.6","Tissue RNA - choroid plexus [nTPM]":"49.9","Tissue RNA - colon [nTPM]":"39.8","Tissue RNA - duodenum [nTPM]":"27.6","Tissue RNA - endometrium 1 [nTPM]":"29.1","Tissue RNA - epididymis [nTPM]":"37.3","Tissue RNA - esophagus [nTPM]":"53.8","Tissue RNA - fallopian tube [nTPM]":"23.3","Tissue RNA - gallbladder [nTPM]":"29.9","Tissue RNA - heart muscle [nTPM]":"32.9","Tissue RNA - hippocampal formation [nTPM]":"38.6","Tissue RNA - hypothalamus [nTPM]":"45.7","Tissue RNA - kidney [nTPM]":"42.7","Tissue RNA - liver [nTPM]":"46.0","Tissue RNA - lung [nTPM]":"34.0","Tissue RNA - lymph node [nTPM]":"47.2","Tissue RNA - medulla oblongata [nTPM]":"38.1","Tissue RNA - midbrain [nTPM]":"34.7","Tissue RNA - ovary [nTPM]":"26.7","Tissue RNA - pancreas [nTPM]":"78.5","Tissue RNA - parathyroid gland [nTPM]":"58.1","Tissue RNA - pituitary gland [nTPM]":"36.5","Tissue RNA - placenta [nTPM]":"39.9","Tissue RNA - pons [nTPM]":"42.0","Tissue RNA - prostate [nTPM]":"26.8","Tissue RNA - rectum [nTPM]":"48.6","Tissue RNA - retina [nTPM]":"46.9","Tissue RNA - salivary gland [nTPM]":"36.1","Tissue RNA - seminal vesicle [nTPM]":"29.3","Tissue RNA - skeletal muscle [nTPM]":"48.1","Tissue RNA - skin 1 [nTPM]":"43.4","Tissue RNA - small intestine [nTPM]":"26.0","Tissue RNA - smooth muscle [nTPM]":"49.8","Tissue RNA - spinal cord [nTPM]":"33.2","Tissue RNA - spleen [nTPM]":"22.3","Tissue RNA - stomach 1 [nTPM]":"47.4","Tissue RNA - testis [nTPM]":"51.5","Tissue RNA - thalamus [nTPM]":"43.4","Tissue RNA - thymus [nTPM]":"40.7","Tissue RNA - thyroid gland [nTPM]":"51.5","Tissue RNA - tongue [nTPM]":"45.0","Tissue RNA - tonsil [nTPM]":"67.3","Tissue RNA - urinary bladder [nTPM]":"54.0","Tissue RNA - vagina [nTPM]":"29.4","Tissue RNA - white matter [nTPM]":"35.2","Cell RNA - A-431 [nTPM]":"231.4","Cell RNA - A549 [nTPM]":"119.8","Cell RNA - AF22 [nTPM]":"103.4","Cell RNA - AN3-CA [nTPM]":"364.5","Cell RNA - ASC diff [nTPM]":"191.9","Cell RNA - ASC TERT1 [nTPM]":"286.8","Cell RNA - BEWO [nTPM]":"172.0","Cell RNA - BJ [nTPM]":"332.4","Cell RNA - BJ hTERT+ [nTPM]":"330.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"184.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"369.8","Cell RNA - CACO-2 [nTPM]":"159.5","Cell RNA - CAPAN-2 [nTPM]":"115.4","Cell RNA - Daudi [nTPM]":"375.9","Cell RNA - EFO-21 [nTPM]":"96.2","Cell RNA - fHDF\/TERT166 [nTPM]":"443.1","Cell RNA - GAMG [nTPM]":"281.6","Cell RNA - HaCaT [nTPM]":"174.5","Cell RNA - HAP1 [nTPM]":"262.6","Cell RNA - HBEC3-KT [nTPM]":"230.2","Cell RNA - HBF TERT88 [nTPM]":"327.7","Cell RNA - HDLM-2 [nTPM]":"92.9","Cell RNA - HEK 293 [nTPM]":"82.5","Cell RNA - HEL [nTPM]":"182.6","Cell RNA - HeLa [nTPM]":"84.8","Cell RNA - Hep G2 [nTPM]":"141.1","Cell RNA - HHSteC [nTPM]":"604.0","Cell RNA - HL-60 [nTPM]":"267.6","Cell RNA - HMC-1 [nTPM]":"149.8","Cell RNA - HSkMC [nTPM]":"272.5","Cell RNA - hTCEpi [nTPM]":"391.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"265.8","Cell RNA - hTERT-HME1 [nTPM]":"304.9","Cell RNA - hTERT-RPE1 [nTPM]":"128.1","Cell RNA - HUVEC TERT2 [nTPM]":"241.6","Cell RNA - JURKAT [nTPM]":"354.1","Cell RNA - K-562 [nTPM]":"350.2","Cell RNA - Karpas-707 [nTPM]":"465.4","Cell RNA - LHCN-M2 [nTPM]":"296.7","Cell RNA - MCF7 [nTPM]":"154.7","Cell RNA - MOLT-4 [nTPM]":"216.8","Cell RNA - NB-4 [nTPM]":"204.3","Cell RNA - NTERA-2 [nTPM]":"259.6","Cell RNA - OE19 [nTPM]":"222.4","Cell RNA - PC-3 [nTPM]":"183.4","Cell RNA - REH [nTPM]":"114.0","Cell RNA - RH-30 [nTPM]":"90.1","Cell RNA - RPMI-8226 [nTPM]":"299.0","Cell RNA - RPTEC TERT1 [nTPM]":"219.5","Cell RNA - RT4 [nTPM]":"109.1","Cell RNA - SCLC-21H [nTPM]":"117.9","Cell RNA - SH-SY5Y [nTPM]":"177.4","Cell RNA - SiHa [nTPM]":"88.1","Cell RNA - SK-BR-3 [nTPM]":"261.5","Cell RNA - SK-MEL-30 [nTPM]":"509.2","Cell RNA - SuSa [nTPM]":"182.8","Cell RNA - T-47d [nTPM]":"225.3","Cell RNA - THP-1 [nTPM]":"409.3","Cell RNA - TIME [nTPM]":"208.2","Cell RNA - U-138 MG [nTPM]":"82.2","Cell RNA - U-2 OS [nTPM]":"262.9","Cell RNA - U-2197 [nTPM]":"164.9","Cell RNA - U-251 MG [nTPM]":"217.9","Cell RNA - U-266\/70 [nTPM]":"403.8","Cell RNA - U-266\/84 [nTPM]":"390.8","Cell RNA - U-698 [nTPM]":"445.9","Cell RNA - U-87 MG [nTPM]":"289.4","Cell RNA - U-937 [nTPM]":"398.8","Cell RNA - WM-115 [nTPM]":"392.9","Blood RNA - basophil [nTPM]":"40.0","Blood RNA - classical monocyte [nTPM]":"27.0","Blood RNA - eosinophil [nTPM]":"24.1","Blood RNA - gdT-cell [nTPM]":"22.9","Blood RNA - intermediate monocyte [nTPM]":"35.8","Blood RNA - MAIT T-cell [nTPM]":"27.4","Blood RNA - memory B-cell [nTPM]":"21.0","Blood RNA - memory CD4 T-cell [nTPM]":"26.0","Blood RNA - memory CD8 T-cell [nTPM]":"28.8","Blood RNA - myeloid DC [nTPM]":"35.8","Blood RNA - naive B-cell [nTPM]":"16.3","Blood RNA - naive CD4 T-cell [nTPM]":"25.2","Blood RNA - naive CD8 T-cell [nTPM]":"30.2","Blood RNA - neutrophil [nTPM]":"5.2","Blood RNA - NK-cell [nTPM]":"20.9","Blood RNA - non-classical monocyte [nTPM]":"41.7","Blood RNA - plasmacytoid DC [nTPM]":"18.5","Blood RNA - T-reg [nTPM]":"31.9","Blood RNA - total PBMC [nTPM]":"23.9","Brain RNA - amygdala [nTPM]":"33.3","Brain RNA - basal ganglia [nTPM]":"36.5","Brain RNA - cerebellum [nTPM]":"34.2","Brain RNA - cerebral cortex [nTPM]":"46.2","Brain RNA - hippocampal formation [nTPM]":"38.6","Brain RNA - hypothalamus [nTPM]":"45.7","Brain RNA - medulla oblongata [nTPM]":"38.1","Brain RNA - midbrain [nTPM]":"34.7","Brain RNA - pons [nTPM]":"42.0","Brain RNA - spinal cord [nTPM]":"33.2","Brain RNA - thalamus [nTPM]":"43.4","Brain RNA - white matter [nTPM]":"35.2","Single Cell Type RNA - Adipocytes [nTPM]":"10.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.0","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"70.0","Single Cell Type RNA - Fibroblasts [nTPM]":"13.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.8","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GBA","Gene synonym":["GBA1","GLUC"],"Ensembl":"ENSG00000177628","Gene description":"Glucosylceramidase beta","Uniprot":["P04062"],"Chromosome":"1","Position":"155234452-155244699","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Sphingolipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Glycosidase","Glycosyltransferase","Hydrolase","Transferase"],"Disease involvement":["Disease variant","Gaucher disease","Ichthyosis","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"65.2","Syncytiotrophoblasts":"59.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006667","CAB037171","CAB037289"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037171":"AB_1078958","CAB037289":"AB_1078957","HPA006667":"AB_1078979"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.9","Tissue RNA - adrenal gland [nTPM]":"37.9","Tissue RNA - amygdala [nTPM]":"22.5","Tissue RNA - appendix [nTPM]":"24.8","Tissue RNA - basal ganglia [nTPM]":"24.4","Tissue RNA - bone marrow [nTPM]":"41.7","Tissue RNA - breast [nTPM]":"25.1","Tissue RNA - cerebellum [nTPM]":"25.9","Tissue RNA - cerebral cortex [nTPM]":"24.3","Tissue RNA - cervix [nTPM]":"26.7","Tissue RNA - choroid plexus [nTPM]":"27.4","Tissue RNA - colon [nTPM]":"35.1","Tissue RNA - duodenum [nTPM]":"23.9","Tissue RNA - endometrium 1 [nTPM]":"22.9","Tissue RNA - epididymis [nTPM]":"50.2","Tissue RNA - esophagus [nTPM]":"27.6","Tissue RNA - fallopian tube [nTPM]":"20.5","Tissue RNA - gallbladder [nTPM]":"28.3","Tissue RNA - heart muscle [nTPM]":"19.1","Tissue RNA - hippocampal formation [nTPM]":"26.1","Tissue RNA - hypothalamus [nTPM]":"27.7","Tissue RNA - kidney [nTPM]":"33.6","Tissue RNA - liver [nTPM]":"33.7","Tissue RNA - lung [nTPM]":"28.3","Tissue RNA - lymph node [nTPM]":"19.9","Tissue RNA - medulla oblongata [nTPM]":"27.3","Tissue RNA - midbrain [nTPM]":"28.0","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"33.4","Tissue RNA - parathyroid gland [nTPM]":"103.1","Tissue RNA - pituitary gland [nTPM]":"43.8","Tissue RNA - placenta [nTPM]":"39.2","Tissue RNA - pons [nTPM]":"36.2","Tissue RNA - prostate [nTPM]":"23.3","Tissue RNA - rectum [nTPM]":"39.8","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"26.8","Tissue RNA - seminal vesicle [nTPM]":"33.6","Tissue RNA - skeletal muscle [nTPM]":"9.1","Tissue RNA - skin 1 [nTPM]":"33.4","Tissue RNA - small intestine [nTPM]":"22.5","Tissue RNA - smooth muscle [nTPM]":"29.7","Tissue RNA - spinal cord [nTPM]":"25.0","Tissue RNA - spleen [nTPM]":"29.0","Tissue RNA - stomach 1 [nTPM]":"22.7","Tissue RNA - testis [nTPM]":"8.8","Tissue RNA - thalamus [nTPM]":"29.2","Tissue RNA - thymus [nTPM]":"19.7","Tissue RNA - thyroid gland [nTPM]":"37.7","Tissue RNA - tongue [nTPM]":"13.6","Tissue RNA - tonsil [nTPM]":"28.0","Tissue RNA - urinary bladder [nTPM]":"27.1","Tissue RNA - vagina [nTPM]":"21.9","Tissue RNA - white matter [nTPM]":"29.5","Cell RNA - A-431 [nTPM]":"38.0","Cell RNA - A549 [nTPM]":"72.2","Cell RNA - AF22 [nTPM]":"25.1","Cell RNA - AN3-CA [nTPM]":"34.2","Cell RNA - ASC diff [nTPM]":"254.8","Cell RNA - ASC TERT1 [nTPM]":"55.8","Cell RNA - BEWO [nTPM]":"29.3","Cell RNA - BJ [nTPM]":"65.4","Cell RNA - BJ hTERT+ [nTPM]":"230.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"95.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"119.0","Cell RNA - CACO-2 [nTPM]":"43.2","Cell RNA - CAPAN-2 [nTPM]":"135.7","Cell RNA - Daudi [nTPM]":"26.3","Cell RNA - EFO-21 [nTPM]":"70.4","Cell RNA - fHDF\/TERT166 [nTPM]":"153.7","Cell RNA - GAMG [nTPM]":"152.0","Cell RNA - HaCaT [nTPM]":"76.2","Cell RNA - HAP1 [nTPM]":"35.9","Cell RNA - HBEC3-KT [nTPM]":"46.4","Cell RNA - HBF TERT88 [nTPM]":"50.3","Cell RNA - HDLM-2 [nTPM]":"55.5","Cell RNA - HEK 293 [nTPM]":"25.1","Cell RNA - HEL [nTPM]":"21.8","Cell RNA - HeLa [nTPM]":"45.1","Cell RNA - Hep G2 [nTPM]":"23.2","Cell RNA - HHSteC [nTPM]":"73.6","Cell RNA - HL-60 [nTPM]":"25.8","Cell RNA - HMC-1 [nTPM]":"87.0","Cell RNA - HSkMC [nTPM]":"73.4","Cell RNA - hTCEpi [nTPM]":"38.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"199.7","Cell RNA - hTERT-HME1 [nTPM]":"30.2","Cell RNA - hTERT-RPE1 [nTPM]":"100.2","Cell RNA - HUVEC TERT2 [nTPM]":"85.6","Cell RNA - JURKAT [nTPM]":"22.2","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"42.9","Cell RNA - LHCN-M2 [nTPM]":"113.5","Cell RNA - MCF7 [nTPM]":"82.6","Cell RNA - MOLT-4 [nTPM]":"32.5","Cell RNA - NB-4 [nTPM]":"11.9","Cell RNA - NTERA-2 [nTPM]":"16.3","Cell RNA - OE19 [nTPM]":"61.9","Cell RNA - PC-3 [nTPM]":"51.2","Cell RNA - REH [nTPM]":"26.8","Cell RNA - RH-30 [nTPM]":"41.9","Cell RNA - RPMI-8226 [nTPM]":"108.1","Cell RNA - RPTEC TERT1 [nTPM]":"63.9","Cell RNA - RT4 [nTPM]":"29.0","Cell RNA - SCLC-21H [nTPM]":"23.9","Cell RNA - SH-SY5Y [nTPM]":"33.5","Cell RNA - SiHa [nTPM]":"57.4","Cell RNA - SK-BR-3 [nTPM]":"136.4","Cell RNA - SK-MEL-30 [nTPM]":"145.3","Cell RNA - SuSa [nTPM]":"45.6","Cell RNA - T-47d [nTPM]":"102.6","Cell RNA - THP-1 [nTPM]":"63.3","Cell RNA - TIME [nTPM]":"65.7","Cell RNA - U-138 MG [nTPM]":"71.7","Cell RNA - U-2 OS [nTPM]":"31.7","Cell RNA - U-2197 [nTPM]":"91.9","Cell RNA - U-251 MG [nTPM]":"53.7","Cell RNA - U-266\/70 [nTPM]":"86.2","Cell RNA - U-266\/84 [nTPM]":"78.6","Cell RNA - U-698 [nTPM]":"20.4","Cell RNA - U-87 MG [nTPM]":"126.6","Cell RNA - U-937 [nTPM]":"23.4","Cell RNA - WM-115 [nTPM]":"56.4","Blood RNA - basophil [nTPM]":"21.4","Blood RNA - classical monocyte [nTPM]":"36.0","Blood RNA - eosinophil [nTPM]":"15.3","Blood RNA - gdT-cell [nTPM]":"20.8","Blood RNA - intermediate monocyte [nTPM]":"35.8","Blood RNA - MAIT T-cell [nTPM]":"13.2","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"15.7","Blood RNA - memory CD8 T-cell [nTPM]":"13.8","Blood RNA - myeloid DC [nTPM]":"22.4","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"11.0","Blood RNA - naive CD8 T-cell [nTPM]":"11.7","Blood RNA - neutrophil [nTPM]":"28.9","Blood RNA - NK-cell [nTPM]":"11.6","Blood RNA - non-classical monocyte [nTPM]":"37.2","Blood RNA - plasmacytoid DC [nTPM]":"12.5","Blood RNA - T-reg [nTPM]":"23.4","Blood RNA - total PBMC [nTPM]":"23.3","Brain RNA - amygdala [nTPM]":"22.5","Brain RNA - basal ganglia [nTPM]":"24.4","Brain RNA - cerebellum [nTPM]":"25.9","Brain RNA - cerebral cortex [nTPM]":"24.3","Brain RNA - hippocampal formation [nTPM]":"26.1","Brain RNA - hypothalamus [nTPM]":"27.7","Brain RNA - medulla oblongata [nTPM]":"27.3","Brain RNA - midbrain [nTPM]":"28.0","Brain RNA - pons [nTPM]":"36.2","Brain RNA - spinal cord [nTPM]":"25.0","Brain RNA - thalamus [nTPM]":"29.2","Brain RNA - white matter [nTPM]":"29.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"8.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.7","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"30.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.9","Single Cell Type RNA - Fibroblasts [nTPM]":"18.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.9","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"7.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"23.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"65.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"33.3","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"26.8","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"22.8","Single Cell Type RNA - Muller glia cells [nTPM]":"11.7","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.5","Single Cell Type RNA - Paneth cells [nTPM]":"15.8","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"19.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.6","Single Cell Type RNA - Spermatocytes [nTPM]":"22.5","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.4","Single Cell Type RNA - T-cells [nTPM]":"8.5","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"GBA2","Gene synonym":["AD035","DKFZp762K054","KIAA1605","SPG46"],"Ensembl":"ENSG00000070610","Gene description":"Glucosylceramidase beta 2","Uniprot":["Q9HCG7"],"Chromosome":"9","Position":"35736866-35749228","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Sphingolipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Glycosidase","Glycosyltransferase","Hydrolase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"114.7","Rod photoreceptor cells":"102.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024026"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA024026":"AB_1849530"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.00e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.24e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.60e-4"},"Tissue RNA - adipose tissue [nTPM]":"39.3","Tissue RNA - adrenal gland [nTPM]":"45.7","Tissue RNA - amygdala [nTPM]":"48.5","Tissue RNA - appendix [nTPM]":"23.2","Tissue RNA - basal ganglia [nTPM]":"47.5","Tissue RNA - bone marrow [nTPM]":"16.3","Tissue RNA - breast [nTPM]":"39.9","Tissue RNA - cerebellum [nTPM]":"52.8","Tissue RNA - cerebral cortex [nTPM]":"53.7","Tissue RNA - cervix [nTPM]":"46.4","Tissue RNA - choroid plexus [nTPM]":"63.3","Tissue RNA - colon [nTPM]":"83.5","Tissue RNA - duodenum [nTPM]":"54.2","Tissue RNA - endometrium 1 [nTPM]":"44.6","Tissue RNA - epididymis [nTPM]":"26.9","Tissue RNA - esophagus [nTPM]":"36.3","Tissue RNA - fallopian tube [nTPM]":"44.2","Tissue RNA - gallbladder [nTPM]":"26.3","Tissue RNA - heart muscle [nTPM]":"83.3","Tissue RNA - hippocampal formation [nTPM]":"47.2","Tissue RNA - hypothalamus [nTPM]":"54.2","Tissue RNA - kidney [nTPM]":"84.4","Tissue RNA - liver [nTPM]":"65.9","Tissue RNA - lung [nTPM]":"54.1","Tissue RNA - lymph node [nTPM]":"24.6","Tissue RNA - medulla oblongata [nTPM]":"54.1","Tissue RNA - midbrain [nTPM]":"56.2","Tissue RNA - ovary [nTPM]":"39.8","Tissue RNA - pancreas [nTPM]":"54.1","Tissue RNA - parathyroid gland [nTPM]":"37.2","Tissue RNA - pituitary gland [nTPM]":"65.5","Tissue RNA - placenta [nTPM]":"24.7","Tissue RNA - pons [nTPM]":"56.1","Tissue RNA - prostate [nTPM]":"60.2","Tissue RNA - rectum [nTPM]":"41.0","Tissue RNA - retina [nTPM]":"71.1","Tissue RNA - salivary gland [nTPM]":"50.0","Tissue RNA - seminal vesicle [nTPM]":"27.7","Tissue RNA - skeletal muscle [nTPM]":"75.8","Tissue RNA - skin 1 [nTPM]":"39.3","Tissue RNA - small intestine [nTPM]":"89.7","Tissue RNA - smooth muscle [nTPM]":"22.9","Tissue RNA - spinal cord [nTPM]":"45.1","Tissue RNA - spleen [nTPM]":"58.5","Tissue RNA - stomach 1 [nTPM]":"63.9","Tissue RNA - testis [nTPM]":"30.8","Tissue RNA - thalamus [nTPM]":"58.9","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"61.7","Tissue RNA - tongue [nTPM]":"43.7","Tissue RNA - tonsil [nTPM]":"21.6","Tissue RNA - urinary bladder [nTPM]":"53.0","Tissue RNA - vagina [nTPM]":"40.9","Tissue RNA - white matter [nTPM]":"48.7","Cell RNA - A-431 [nTPM]":"18.1","Cell RNA - A549 [nTPM]":"29.3","Cell RNA - AF22 [nTPM]":"39.6","Cell RNA - AN3-CA [nTPM]":"38.4","Cell RNA - ASC diff [nTPM]":"18.8","Cell RNA - ASC TERT1 [nTPM]":"11.4","Cell RNA - BEWO [nTPM]":"40.0","Cell RNA - BJ [nTPM]":"24.1","Cell RNA - BJ hTERT+ [nTPM]":"18.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.0","Cell RNA - CACO-2 [nTPM]":"32.8","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"19.3","Cell RNA - EFO-21 [nTPM]":"17.1","Cell RNA - fHDF\/TERT166 [nTPM]":"14.7","Cell RNA - GAMG [nTPM]":"51.5","Cell RNA - HaCaT [nTPM]":"18.4","Cell RNA - HAP1 [nTPM]":"38.2","Cell RNA - HBEC3-KT [nTPM]":"16.2","Cell RNA - HBF TERT88 [nTPM]":"12.0","Cell RNA - HDLM-2 [nTPM]":"27.5","Cell RNA - HEK 293 [nTPM]":"26.2","Cell RNA - HEL [nTPM]":"20.8","Cell RNA - HeLa [nTPM]":"87.8","Cell RNA - Hep G2 [nTPM]":"35.6","Cell RNA - HHSteC [nTPM]":"20.8","Cell RNA - HL-60 [nTPM]":"31.2","Cell RNA - HMC-1 [nTPM]":"49.4","Cell RNA - HSkMC [nTPM]":"19.8","Cell RNA - hTCEpi [nTPM]":"29.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.3","Cell RNA - hTERT-HME1 [nTPM]":"21.1","Cell RNA - hTERT-RPE1 [nTPM]":"57.9","Cell RNA - HUVEC TERT2 [nTPM]":"63.4","Cell RNA - JURKAT [nTPM]":"18.9","Cell RNA - K-562 [nTPM]":"20.7","Cell RNA - Karpas-707 [nTPM]":"36.0","Cell RNA - LHCN-M2 [nTPM]":"22.6","Cell RNA - MCF7 [nTPM]":"18.0","Cell RNA - MOLT-4 [nTPM]":"8.5","Cell RNA - NB-4 [nTPM]":"32.0","Cell RNA - NTERA-2 [nTPM]":"41.2","Cell RNA - OE19 [nTPM]":"36.6","Cell RNA - PC-3 [nTPM]":"45.7","Cell RNA - REH [nTPM]":"15.5","Cell RNA - RH-30 [nTPM]":"16.0","Cell RNA - RPMI-8226 [nTPM]":"16.3","Cell RNA - RPTEC TERT1 [nTPM]":"33.3","Cell RNA - RT4 [nTPM]":"41.9","Cell RNA - SCLC-21H [nTPM]":"32.2","Cell RNA - SH-SY5Y [nTPM]":"43.0","Cell RNA - SiHa [nTPM]":"13.5","Cell RNA - SK-BR-3 [nTPM]":"33.3","Cell RNA - SK-MEL-30 [nTPM]":"24.5","Cell RNA - SuSa [nTPM]":"48.1","Cell RNA - T-47d [nTPM]":"22.8","Cell RNA - THP-1 [nTPM]":"27.8","Cell RNA - TIME [nTPM]":"44.6","Cell RNA - U-138 MG [nTPM]":"25.8","Cell RNA - U-2 OS [nTPM]":"30.9","Cell RNA - U-2197 [nTPM]":"22.4","Cell RNA - U-251 MG [nTPM]":"29.9","Cell RNA - U-266\/70 [nTPM]":"24.2","Cell RNA - U-266\/84 [nTPM]":"16.5","Cell RNA - U-698 [nTPM]":"16.0","Cell RNA - U-87 MG [nTPM]":"32.3","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"20.5","Blood RNA - basophil [nTPM]":"11.1","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"3.8","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.7","Blood RNA - memory CD8 T-cell [nTPM]":"4.7","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"4.7","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"48.5","Brain RNA - basal ganglia [nTPM]":"47.5","Brain RNA - cerebellum [nTPM]":"52.8","Brain RNA - cerebral cortex [nTPM]":"53.7","Brain RNA - hippocampal formation [nTPM]":"47.2","Brain RNA - hypothalamus [nTPM]":"54.2","Brain RNA - medulla oblongata [nTPM]":"54.1","Brain RNA - midbrain [nTPM]":"56.2","Brain RNA - pons [nTPM]":"56.1","Brain RNA - spinal cord [nTPM]":"45.1","Brain RNA - thalamus [nTPM]":"58.9","Brain RNA - white matter [nTPM]":"48.7","Single Cell Type RNA - Adipocytes [nTPM]":"12.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.0","Single Cell Type RNA - Astrocytes [nTPM]":"45.1","Single Cell Type RNA - B-cells [nTPM]":"11.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"77.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"14.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"114.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - dendritic cells [nTPM]":"16.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"71.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"10.5","Single Cell Type RNA - Early spermatids [nTPM]":"14.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"16.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.8","Single Cell Type RNA - Erythroid cells [nTPM]":"17.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.2","Single Cell Type RNA - Fibroblasts [nTPM]":"8.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.8","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"18.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.7","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.8","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"24.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"10.7","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"13.3","Single Cell Type RNA - Muller glia cells [nTPM]":"16.2","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.1","Single Cell Type RNA - Paneth cells [nTPM]":"57.6","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"11.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"87.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"102.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.2","Single Cell Type RNA - Spermatocytes [nTPM]":"9.2","Single Cell Type RNA - Spermatogonia [nTPM]":"5.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - T-cells [nTPM]":"9.4","Single Cell Type RNA - Theca cells [nTPM]":"11.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.4","Single Cell Type RNA - Urothelial cells [nTPM]":"26.3"},{"Gene":"GCH1","Gene synonym":["DYT14","DYT5","DYT5a","GCH","GTPCH1"],"Ensembl":"ENSG00000131979","Gene description":"GTP cyclohydrolase 1","Uniprot":["P30793"],"Chromosome":"14","Position":"54842008-54902826","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tetrahydrobiopterin biosynthesis"],"Molecular function":["Allosteric enzyme","Hydrolase"],"Disease involvement":["Disease variant","Dystonia","Parkinsonism","Phenylketonuria"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"31.4","liver":"36.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"212.5","Hepatocytes":"94.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"11.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"23.5","Daudi":"25.0","JURKAT":"23.0","SH-SY5Y":"50.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"12.7"},"Antibody":["HPA028612"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane","Cytosol"],"Antibody RRID":{"HPA028612":"AB_10602135"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.69e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.41e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.67e-4"},"Tissue RNA - adipose tissue [nTPM]":"2.4","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"31.4","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"9.4","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"36.7","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"7.0","Tissue RNA - medulla oblongata [nTPM]":"3.5","Tissue RNA - midbrain [nTPM]":"16.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"8.4","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"6.9","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"7.8","Tissue RNA - thymus [nTPM]":"3.8","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"3.3","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"23.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.9","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"25.0","Cell RNA - EFO-21 [nTPM]":"6.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"5.8","Cell RNA - HaCaT [nTPM]":"4.0","Cell RNA - HAP1 [nTPM]":"4.9","Cell RNA - HBEC3-KT [nTPM]":"1.5","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"3.1","Cell RNA - HHSteC [nTPM]":"8.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.2","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"23.0","Cell RNA - K-562 [nTPM]":"2.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"15.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"6.5","Cell RNA - PC-3 [nTPM]":"8.2","Cell RNA - REH [nTPM]":"9.6","Cell RNA - RH-30 [nTPM]":"2.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"11.6","Cell RNA - SH-SY5Y [nTPM]":"50.9","Cell RNA - SiHa [nTPM]":"3.3","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"4.0","Cell RNA - U-2197 [nTPM]":"9.9","Cell RNA - U-251 MG [nTPM]":"3.8","Cell RNA - U-266\/70 [nTPM]":"10.5","Cell RNA - U-266\/84 [nTPM]":"8.4","Cell RNA - U-698 [nTPM]":"7.8","Cell RNA - U-87 MG [nTPM]":"3.1","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"2.8","Blood RNA - intermediate monocyte [nTPM]":"5.3","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"11.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"3.5","Brain RNA - midbrain [nTPM]":"16.1","Brain RNA - pons [nTPM]":"8.4","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"7.8","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"33.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"74.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"13.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"50.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.8","Single Cell Type RNA - Endothelial cells [nTPM]":"19.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"212.5","Single Cell Type RNA - Erythroid cells [nTPM]":"10.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.3","Single Cell Type RNA - Fibroblasts [nTPM]":"15.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"94.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"28.0","Single Cell Type RNA - Langerhans cells [nTPM]":"33.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"55.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"29.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.0","Single Cell Type RNA - Paneth cells [nTPM]":"13.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.5","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"76.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"41.8","Single Cell Type RNA - Theca cells [nTPM]":"11.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.2","Single Cell Type RNA - Urothelial cells [nTPM]":"39.0"},{"Gene":"GCNT2","Gene synonym":["bA360O19.2","bA421M1.1","CCAT","GCNT5","IGNT","II","NACGT1","NAGCT1","ULG3"],"Ensembl":"ENSG00000111846","Gene description":"Glucosaminyl (N-acetyl) transferase 2 (I blood group)","Uniprot":["Q8N0V5"],"Chromosome":"6","Position":"10492223-10629368","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"13.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"76.9","Endometrial ciliated cells":"79.1","Glandular and luminal cells":"105.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"44.2","Hep G2":"19.7","SK-MEL-30":"17.1","SuSa":"21.4"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"61.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026776"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"750000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA026776":"AB_1849573"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"10.1","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"4.2","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"5.1","Tissue RNA - lung [nTPM]":"3.9","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"1.5","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"6.3","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"4.8","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"9.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"11.0","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"3.5","Cell RNA - EFO-21 [nTPM]":"44.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.2","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"5.1","Cell RNA - HBF TERT88 [nTPM]":"2.9","Cell RNA - HDLM-2 [nTPM]":"3.1","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"19.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.7","Cell RNA - HMC-1 [nTPM]":"4.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.4","Cell RNA - HUVEC TERT2 [nTPM]":"9.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"4.0","Cell RNA - NTERA-2 [nTPM]":"4.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"3.8","Cell RNA - RPMI-8226 [nTPM]":"6.0","Cell RNA - RPTEC TERT1 [nTPM]":"16.0","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"14.4","Cell RNA - SK-MEL-30 [nTPM]":"17.1","Cell RNA - SuSa [nTPM]":"21.4","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"6.4","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"5.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"2.3","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"9.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"28.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"2.9","Single Cell Type RNA - Early spermatids [nTPM]":"4.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"79.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.5","Single Cell Type RNA - Endothelial cells [nTPM]":"11.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"25.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"105.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"32.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"9.4","Single Cell Type RNA - Late spermatids [nTPM]":"8.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"49.8","Single Cell Type RNA - Microglial cells [nTPM]":"52.5","Single Cell Type RNA - monocytes [nTPM]":"11.1","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.0","Single Cell Type RNA - Paneth cells [nTPM]":"11.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"44.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"27.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.3","Single Cell Type RNA - Urothelial cells [nTPM]":"8.1"},{"Gene":"GDAP1","Gene synonym":["CMT2K","CMT4","CMT4A"],"Ensembl":"ENSG00000104381","Gene description":"Ganglioside induced differentiation associated protein 1","Uniprot":["Q8TB36"],"Chromosome":"8","Position":"74320613-74518007","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"26.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"46.9","Cone photoreceptor cells":"47.9","Excitatory neurons":"75.7","Horizontal cells":"47.1","Inhibitory neurons":"67.3","Oligodendrocyte precursor cells":"67.8","Rod photoreceptor cells":"47.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SH-SY5Y":"38.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014266","HPA024334"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA014266":"AB_1849581","HPA024334":"AB_1849583"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.68e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.54e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.7","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"19.0","Tissue RNA - appendix [nTPM]":"3.3","Tissue RNA - basal ganglia [nTPM]":"22.5","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"26.0","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"4.9","Tissue RNA - colon [nTPM]":"2.5","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"25.3","Tissue RNA - hypothalamus [nTPM]":"19.7","Tissue RNA - kidney [nTPM]":"4.2","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"14.5","Tissue RNA - midbrain [nTPM]":"17.0","Tissue RNA - ovary [nTPM]":"6.0","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"12.4","Tissue RNA - pituitary gland [nTPM]":"20.6","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"18.1","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"19.0","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"2.3","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"16.7","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"6.6","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"3.9","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"20.5","Cell RNA - A-431 [nTPM]":"3.5","Cell RNA - A549 [nTPM]":"16.8","Cell RNA - AF22 [nTPM]":"17.7","Cell RNA - AN3-CA [nTPM]":"4.8","Cell RNA - ASC diff [nTPM]":"1.2","Cell RNA - ASC TERT1 [nTPM]":"1.6","Cell RNA - BEWO [nTPM]":"1.5","Cell RNA - BJ [nTPM]":"1.8","Cell RNA - BJ hTERT+ [nTPM]":"8.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.5","Cell RNA - CACO-2 [nTPM]":"7.8","Cell RNA - CAPAN-2 [nTPM]":"5.0","Cell RNA - Daudi [nTPM]":"14.8","Cell RNA - EFO-21 [nTPM]":"2.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"10.6","Cell RNA - HaCaT [nTPM]":"6.6","Cell RNA - HAP1 [nTPM]":"12.4","Cell RNA - HBEC3-KT [nTPM]":"7.0","Cell RNA - HBF TERT88 [nTPM]":"16.2","Cell RNA - HDLM-2 [nTPM]":"19.7","Cell RNA - HEK 293 [nTPM]":"3.6","Cell RNA - HEL [nTPM]":"7.4","Cell RNA - HeLa [nTPM]":"8.9","Cell RNA - Hep G2 [nTPM]":"14.0","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"7.6","Cell RNA - HMC-1 [nTPM]":"15.8","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"2.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.3","Cell RNA - hTERT-HME1 [nTPM]":"8.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"1.1","Cell RNA - JURKAT [nTPM]":"7.3","Cell RNA - K-562 [nTPM]":"3.4","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"4.8","Cell RNA - MCF7 [nTPM]":"5.7","Cell RNA - MOLT-4 [nTPM]":"12.6","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"20.1","Cell RNA - OE19 [nTPM]":"24.5","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"8.7","Cell RNA - RH-30 [nTPM]":"9.2","Cell RNA - RPMI-8226 [nTPM]":"3.2","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"15.3","Cell RNA - SCLC-21H [nTPM]":"18.2","Cell RNA - SH-SY5Y [nTPM]":"38.9","Cell RNA - SiHa [nTPM]":"13.1","Cell RNA - SK-BR-3 [nTPM]":"3.4","Cell RNA - SK-MEL-30 [nTPM]":"9.7","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"14.9","Cell RNA - THP-1 [nTPM]":"2.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"11.7","Cell RNA - U-2 OS [nTPM]":"6.2","Cell RNA - U-2197 [nTPM]":"2.9","Cell RNA - U-251 MG [nTPM]":"5.5","Cell RNA - U-266\/70 [nTPM]":"9.3","Cell RNA - U-266\/84 [nTPM]":"15.7","Cell RNA - U-698 [nTPM]":"6.8","Cell RNA - U-87 MG [nTPM]":"7.3","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"13.8","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"4.0","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"19.0","Brain RNA - basal ganglia [nTPM]":"22.5","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"26.0","Brain RNA - hippocampal formation [nTPM]":"25.3","Brain RNA - hypothalamus [nTPM]":"19.7","Brain RNA - medulla oblongata [nTPM]":"14.5","Brain RNA - midbrain [nTPM]":"17.0","Brain RNA - pons [nTPM]":"18.1","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"16.7","Brain RNA - white matter [nTPM]":"20.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"46.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"3.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"5.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"75.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"17.2","Single Cell Type RNA - Granulosa cells [nTPM]":"2.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"67.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"4.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"2.9","Single Cell Type RNA - Muller glia cells [nTPM]":"23.5","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"67.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"41.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"47.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.5","Single Cell Type RNA - Spermatocytes [nTPM]":"14.7","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"6.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"GDAP2","Gene synonym":["dJ776P7.1","FLJ20142","MACROD3"],"Ensembl":"ENSG00000196505","Gene description":"Ganglioside induced differentiation associated protein 2","Uniprot":["Q9NXN4"],"Chromosome":"1","Position":"117863485-117929621","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046185"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA046185":"AB_10960897"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"3.2","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"3.2","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"3.4","Tissue RNA - choroid plexus [nTPM]":"3.4","Tissue RNA - colon [nTPM]":"3.8","Tissue RNA - duodenum [nTPM]":"4.0","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"2.5","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"5.1","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"2.4","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"4.9","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"3.0","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"3.0","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"3.1","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"9.2","Cell RNA - A549 [nTPM]":"5.1","Cell RNA - AF22 [nTPM]":"6.1","Cell RNA - AN3-CA [nTPM]":"5.1","Cell RNA - ASC diff [nTPM]":"6.5","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"9.0","Cell RNA - BJ [nTPM]":"5.2","Cell RNA - BJ hTERT+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.9","Cell RNA - CACO-2 [nTPM]":"5.4","Cell RNA - CAPAN-2 [nTPM]":"6.2","Cell RNA - Daudi [nTPM]":"3.6","Cell RNA - EFO-21 [nTPM]":"6.2","Cell RNA - fHDF\/TERT166 [nTPM]":"7.1","Cell RNA - GAMG [nTPM]":"7.8","Cell RNA - HaCaT [nTPM]":"5.3","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"6.8","Cell RNA - HBF TERT88 [nTPM]":"12.6","Cell RNA - HDLM-2 [nTPM]":"7.2","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"5.4","Cell RNA - HeLa [nTPM]":"6.7","Cell RNA - Hep G2 [nTPM]":"5.9","Cell RNA - HHSteC [nTPM]":"7.7","Cell RNA - HL-60 [nTPM]":"6.8","Cell RNA - HMC-1 [nTPM]":"6.6","Cell RNA - HSkMC [nTPM]":"2.5","Cell RNA - hTCEpi [nTPM]":"8.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.9","Cell RNA - hTERT-HME1 [nTPM]":"9.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.7","Cell RNA - HUVEC TERT2 [nTPM]":"6.9","Cell RNA - JURKAT [nTPM]":"8.1","Cell RNA - K-562 [nTPM]":"5.7","Cell RNA - Karpas-707 [nTPM]":"7.6","Cell RNA - LHCN-M2 [nTPM]":"8.6","Cell RNA - MCF7 [nTPM]":"9.6","Cell RNA - MOLT-4 [nTPM]":"6.0","Cell RNA - NB-4 [nTPM]":"5.5","Cell RNA - NTERA-2 [nTPM]":"10.6","Cell RNA - OE19 [nTPM]":"6.9","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"3.2","Cell RNA - RH-30 [nTPM]":"16.7","Cell RNA - RPMI-8226 [nTPM]":"5.3","Cell RNA - RPTEC TERT1 [nTPM]":"5.8","Cell RNA - RT4 [nTPM]":"9.1","Cell RNA - SCLC-21H [nTPM]":"4.6","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"6.3","Cell RNA - SK-BR-3 [nTPM]":"10.7","Cell RNA - SK-MEL-30 [nTPM]":"8.2","Cell RNA - SuSa [nTPM]":"18.3","Cell RNA - T-47d [nTPM]":"3.7","Cell RNA - THP-1 [nTPM]":"6.8","Cell RNA - TIME [nTPM]":"4.3","Cell RNA - U-138 MG [nTPM]":"7.3","Cell RNA - U-2 OS [nTPM]":"8.5","Cell RNA - U-2197 [nTPM]":"8.5","Cell RNA - U-251 MG [nTPM]":"7.1","Cell RNA - U-266\/70 [nTPM]":"7.9","Cell RNA - U-266\/84 [nTPM]":"6.1","Cell RNA - U-698 [nTPM]":"5.1","Cell RNA - U-87 MG [nTPM]":"9.4","Cell RNA - U-937 [nTPM]":"4.8","Cell RNA - WM-115 [nTPM]":"9.1","Blood RNA - basophil [nTPM]":"11.4","Blood RNA - classical monocyte [nTPM]":"6.7","Blood RNA - eosinophil [nTPM]":"12.6","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"7.2","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"6.5","Blood RNA - NK-cell [nTPM]":"4.1","Blood RNA - non-classical monocyte [nTPM]":"7.6","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"3.6","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"9.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"13.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"13.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.6","Single Cell Type RNA - Early spermatids [nTPM]":"21.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"13.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"9.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.8","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.2","Single Cell Type RNA - Langerhans cells [nTPM]":"15.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"20.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"16.2","Single Cell Type RNA - Muller glia cells [nTPM]":"9.2","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.7","Single Cell Type RNA - Paneth cells [nTPM]":"7.5","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"21.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.2","Single Cell Type RNA - Spermatocytes [nTPM]":"28.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.3","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"GDF6","Gene synonym":["BMP13","KFS","KFS1","SGM1"],"Ensembl":"ENSG00000156466","Gene description":"Growth differentiation factor 6","Uniprot":["Q6KF10"],"Chromosome":"8","Position":"96142333-96160806","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Cytokine","Developmental protein","Growth factor"],"Disease involvement":["Disease variant","Dwarfism","Leber congenital amaurosis","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"10.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"2.3","Distal tubular cells":"1.9","Excitatory neurons":"1.6","Fibroblasts":"3.1","Oligodendrocyte precursor cells":"7.1","Spermatogonia":"2.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"2.8","thyroid cancer":"2.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"hTERT-RPE1":"20.4","LHCN-M2":"33.1","SuSa":"15.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"1.2"},"Antibody":["HPA045206"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Nuclear membrane"],"Antibody RRID":{"HPA045206":"AB_10962508"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-9"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"10.9","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"3.9","Cell RNA - BJ [nTPM]":"2.6","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"3.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"20.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"33.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"15.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GDNF","Gene synonym":["ATF1","ATF2","HFB1-GDNF"],"Ensembl":"ENSG00000168621","Gene description":"Glial cell derived neurotrophic factor","Uniprot":["P39905"],"Chromosome":"5","Position":"37812677-37840041","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes","Disease variant","Hirschsprung disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"8.2","skeletal muscle":"10.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"3.3","Skeletal myocytes":"11.5","Spermatogonia":"3.4","Theca cells":"2.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTEC\/SVTERT24-B":"41.4","SuSa":"12.6","U-87 MG":"12.6","WM-115":"46.5"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"2.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005210","HPA070283"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB005210":"AB_2247684","HPA070283":"AB_2686246"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"8.2","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"10.1","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"2.0","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"6.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"1.8","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"5.5","Cell RNA - BJ hTERT+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"7.4","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"9.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"2.7","Cell RNA - SuSa [nTPM]":"12.6","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"6.2","Cell RNA - U-266\/70 [nTPM]":"4.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"46.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"6.1","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"2.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"GFAP","Gene synonym":["FLJ45472"],"Ensembl":"ENSG00000131095","Gene description":"Glial fibrillary acidic protein","Uniprot":["P14136"],"Chromosome":"17","Position":"44903159-44916937","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"13076.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"381.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"368","RNA cancer specific FPKM":{"glioma":"2468.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"6.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"6.2","NK-cells":"1.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-87 MG":"6.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000039","HPA056030","HPA063513"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"CAB000039":"AB_10013382","HPA056030":"AB_2683015","HPA063513":"AB_2685027"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"5096.2","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"5407.4","Tissue RNA - bone marrow [nTPM]":"14.1","Tissue RNA - breast [nTPM]":"3.5","Tissue RNA - cerebellum [nTPM]":"5902.8","Tissue RNA - cerebral cortex [nTPM]":"4887.4","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"2342.2","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"3.7","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"8.2","Tissue RNA - hippocampal formation [nTPM]":"5059.3","Tissue RNA - hypothalamus [nTPM]":"9869.7","Tissue RNA - kidney [nTPM]":"2.1","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"1.3","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"13076.3","Tissue RNA - midbrain [nTPM]":"9001.4","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"33.9","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"9204.1","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"117.7","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"10040.2","Tissue RNA - spleen [nTPM]":"1.5","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"8068.5","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"10496.9","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"2.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"2.2","Cell RNA - EFO-21 [nTPM]":"1.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"2.7","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"1.8","Cell RNA - HDLM-2 [nTPM]":"3.0","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"2.1","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"2.2","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.3","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"5.3","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"2.6","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"3.3","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"1.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"1.7","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"1.2","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"1.2","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"2.0","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"1.6","Cell RNA - U-698 [nTPM]":"1.6","Cell RNA - U-87 MG [nTPM]":"6.1","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"2.7","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"6.2","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"5096.2","Brain RNA - basal ganglia [nTPM]":"5407.4","Brain RNA - cerebellum [nTPM]":"5902.8","Brain RNA - cerebral cortex [nTPM]":"4887.4","Brain RNA - hippocampal formation [nTPM]":"5059.3","Brain RNA - hypothalamus [nTPM]":"9869.7","Brain RNA - medulla oblongata [nTPM]":"13076.3","Brain RNA - midbrain [nTPM]":"9001.4","Brain RNA - pons [nTPM]":"9204.1","Brain RNA - spinal cord [nTPM]":"10040.2","Brain RNA - thalamus [nTPM]":"8068.5","Brain RNA - white matter [nTPM]":"10496.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"381.9","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"53.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GFPT1","Gene synonym":["GFA","GFAT","GFAT1","GFPT"],"Ensembl":"ENSG00000198380","Gene description":"Glutamine--fructose-6-phosphate transaminase 1","Uniprot":["Q06210"],"Chromosome":"2","Position":"69319780-69387250","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms"],"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"184.2","Intestinal goblet cells":"244.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047240"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"93000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA047240":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.13e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Tissue RNA - adipose tissue [nTPM]":"31.2","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"21.5","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"15.0","Tissue RNA - breast [nTPM]":"22.4","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"7.1","Tissue RNA - cervix [nTPM]":"37.8","Tissue RNA - choroid plexus [nTPM]":"31.5","Tissue RNA - colon [nTPM]":"74.3","Tissue RNA - duodenum [nTPM]":"38.4","Tissue RNA - endometrium 1 [nTPM]":"15.6","Tissue RNA - epididymis [nTPM]":"41.6","Tissue RNA - esophagus [nTPM]":"16.4","Tissue RNA - fallopian tube [nTPM]":"24.3","Tissue RNA - gallbladder [nTPM]":"32.5","Tissue RNA - heart muscle [nTPM]":"24.8","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"11.0","Tissue RNA - kidney [nTPM]":"21.6","Tissue RNA - liver [nTPM]":"23.1","Tissue RNA - lung [nTPM]":"17.0","Tissue RNA - lymph node [nTPM]":"10.6","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"10.5","Tissue RNA - ovary [nTPM]":"12.0","Tissue RNA - pancreas [nTPM]":"33.7","Tissue RNA - parathyroid gland [nTPM]":"26.2","Tissue RNA - pituitary gland [nTPM]":"18.9","Tissue RNA - placenta [nTPM]":"36.0","Tissue RNA - pons [nTPM]":"10.8","Tissue RNA - prostate [nTPM]":"36.7","Tissue RNA - rectum [nTPM]":"76.6","Tissue RNA - retina [nTPM]":"10.4","Tissue RNA - salivary gland [nTPM]":"42.4","Tissue RNA - seminal vesicle [nTPM]":"25.9","Tissue RNA - skeletal muscle [nTPM]":"10.2","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"41.2","Tissue RNA - smooth muscle [nTPM]":"23.2","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"9.5","Tissue RNA - stomach 1 [nTPM]":"64.3","Tissue RNA - testis [nTPM]":"46.6","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"10.2","Tissue RNA - thyroid gland [nTPM]":"91.8","Tissue RNA - tongue [nTPM]":"13.9","Tissue RNA - tonsil [nTPM]":"15.9","Tissue RNA - urinary bladder [nTPM]":"21.8","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"46.6","Cell RNA - A549 [nTPM]":"42.7","Cell RNA - AF22 [nTPM]":"34.7","Cell RNA - AN3-CA [nTPM]":"20.9","Cell RNA - ASC diff [nTPM]":"107.7","Cell RNA - ASC TERT1 [nTPM]":"75.8","Cell RNA - BEWO [nTPM]":"73.5","Cell RNA - BJ [nTPM]":"97.1","Cell RNA - BJ hTERT+ [nTPM]":"94.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.3","Cell RNA - CACO-2 [nTPM]":"109.5","Cell RNA - CAPAN-2 [nTPM]":"50.5","Cell RNA - Daudi [nTPM]":"31.7","Cell RNA - EFO-21 [nTPM]":"31.9","Cell RNA - fHDF\/TERT166 [nTPM]":"92.9","Cell RNA - GAMG [nTPM]":"61.4","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"47.1","Cell RNA - HBEC3-KT [nTPM]":"28.6","Cell RNA - HBF TERT88 [nTPM]":"73.6","Cell RNA - HDLM-2 [nTPM]":"38.4","Cell RNA - HEK 293 [nTPM]":"18.4","Cell RNA - HEL [nTPM]":"38.2","Cell RNA - HeLa [nTPM]":"25.0","Cell RNA - Hep G2 [nTPM]":"94.5","Cell RNA - HHSteC [nTPM]":"123.0","Cell RNA - HL-60 [nTPM]":"27.9","Cell RNA - HMC-1 [nTPM]":"17.9","Cell RNA - HSkMC [nTPM]":"47.8","Cell RNA - hTCEpi [nTPM]":"132.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"88.7","Cell RNA - hTERT-HME1 [nTPM]":"158.8","Cell RNA - hTERT-RPE1 [nTPM]":"55.5","Cell RNA - HUVEC TERT2 [nTPM]":"43.4","Cell RNA - JURKAT [nTPM]":"29.8","Cell RNA - K-562 [nTPM]":"34.8","Cell RNA - Karpas-707 [nTPM]":"58.3","Cell RNA - LHCN-M2 [nTPM]":"85.2","Cell RNA - MCF7 [nTPM]":"30.9","Cell RNA - MOLT-4 [nTPM]":"31.3","Cell RNA - NB-4 [nTPM]":"22.9","Cell RNA - NTERA-2 [nTPM]":"37.0","Cell RNA - OE19 [nTPM]":"116.7","Cell RNA - PC-3 [nTPM]":"27.4","Cell RNA - REH [nTPM]":"28.2","Cell RNA - RH-30 [nTPM]":"79.1","Cell RNA - RPMI-8226 [nTPM]":"18.3","Cell RNA - RPTEC TERT1 [nTPM]":"70.6","Cell RNA - RT4 [nTPM]":"42.0","Cell RNA - SCLC-21H [nTPM]":"25.2","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"35.2","Cell RNA - SK-BR-3 [nTPM]":"52.4","Cell RNA - SK-MEL-30 [nTPM]":"93.7","Cell RNA - SuSa [nTPM]":"73.5","Cell RNA - T-47d [nTPM]":"22.7","Cell RNA - THP-1 [nTPM]":"17.2","Cell RNA - TIME [nTPM]":"61.8","Cell RNA - U-138 MG [nTPM]":"37.2","Cell RNA - U-2 OS [nTPM]":"62.3","Cell RNA - U-2197 [nTPM]":"64.6","Cell RNA - U-251 MG [nTPM]":"47.5","Cell RNA - U-266\/70 [nTPM]":"39.5","Cell RNA - U-266\/84 [nTPM]":"32.2","Cell RNA - U-698 [nTPM]":"25.4","Cell RNA - U-87 MG [nTPM]":"65.7","Cell RNA - U-937 [nTPM]":"18.3","Cell RNA - WM-115 [nTPM]":"46.9","Blood RNA - basophil [nTPM]":"9.2","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"7.5","Blood RNA - intermediate monocyte [nTPM]":"4.3","Blood RNA - MAIT T-cell [nTPM]":"7.0","Blood RNA - memory B-cell [nTPM]":"6.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.5","Blood RNA - memory CD8 T-cell [nTPM]":"8.3","Blood RNA - myeloid DC [nTPM]":"4.7","Blood RNA - naive B-cell [nTPM]":"3.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.3","Blood RNA - naive CD8 T-cell [nTPM]":"6.2","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"5.2","Blood RNA - non-classical monocyte [nTPM]":"5.2","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"5.0","Blood RNA - total PBMC [nTPM]":"4.2","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"7.1","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"11.0","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"10.5","Brain RNA - pons [nTPM]":"10.8","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"14.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.5","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"29.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"13.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"50.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"54.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.6","Single Cell Type RNA - dendritic cells [nTPM]":"30.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"184.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"123.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"54.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.1","Single Cell Type RNA - Endothelial cells [nTPM]":"17.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"75.1","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"89.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"70.3","Single Cell Type RNA - Fibroblasts [nTPM]":"37.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"110.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.0","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"19.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"53.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"244.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.0","Single Cell Type RNA - Langerhans cells [nTPM]":"31.4","Single Cell Type RNA - Late spermatids [nTPM]":"23.7","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"16.0","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"28.1","Single Cell Type RNA - Muller glia cells [nTPM]":"10.6","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"42.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"66.0","Single Cell Type RNA - Paneth cells [nTPM]":"83.3","Single Cell Type RNA - Peritubular cells [nTPM]":"28.2","Single Cell Type RNA - Plasma cells [nTPM]":"82.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"72.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"62.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"89.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.8","Single Cell Type RNA - Spermatocytes [nTPM]":"134.1","Single Cell Type RNA - Spermatogonia [nTPM]":"45.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.3","Single Cell Type RNA - T-cells [nTPM]":"33.4","Single Cell Type RNA - Theca cells [nTPM]":"15.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"135.3","Single Cell Type RNA - Urothelial cells [nTPM]":"56.3"},{"Gene":"GIGYF2","Gene synonym":["GYF2","KIAA0642","PARK11","PERQ2","PERQ3","TNRC15"],"Ensembl":"ENSG00000204120","Gene description":"GRB10 interacting GYF protein 2","Uniprot":["Q6Y7W6"],"Chromosome":"2","Position":"232697299-232860605","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"333.8","Late spermatids":"563.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050899","HPA054612","HPA059918","HPA065064"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA050899":"AB_2681267","HPA054612":"AB_2682542","HPA059918":"AB_2684160","HPA065064":"AB_2685417"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.97e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.1","Tissue RNA - adrenal gland [nTPM]":"19.4","Tissue RNA - amygdala [nTPM]":"13.5","Tissue RNA - appendix [nTPM]":"19.1","Tissue RNA - basal ganglia [nTPM]":"17.2","Tissue RNA - bone marrow [nTPM]":"21.6","Tissue RNA - breast [nTPM]":"23.1","Tissue RNA - cerebellum [nTPM]":"23.5","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"19.0","Tissue RNA - choroid plexus [nTPM]":"11.4","Tissue RNA - colon [nTPM]":"17.8","Tissue RNA - duodenum [nTPM]":"17.6","Tissue RNA - endometrium 1 [nTPM]":"21.3","Tissue RNA - epididymis [nTPM]":"13.8","Tissue RNA - esophagus [nTPM]":"20.4","Tissue RNA - fallopian tube [nTPM]":"18.1","Tissue RNA - gallbladder [nTPM]":"15.7","Tissue RNA - heart muscle [nTPM]":"25.6","Tissue RNA - hippocampal formation [nTPM]":"13.5","Tissue RNA - hypothalamus [nTPM]":"18.5","Tissue RNA - kidney [nTPM]":"25.2","Tissue RNA - liver [nTPM]":"15.8","Tissue RNA - lung [nTPM]":"16.7","Tissue RNA - lymph node [nTPM]":"20.4","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"27.4","Tissue RNA - pancreas [nTPM]":"25.5","Tissue RNA - parathyroid gland [nTPM]":"40.5","Tissue RNA - pituitary gland [nTPM]":"9.6","Tissue RNA - placenta [nTPM]":"22.0","Tissue RNA - pons [nTPM]":"15.9","Tissue RNA - prostate [nTPM]":"22.0","Tissue RNA - rectum [nTPM]":"19.5","Tissue RNA - retina [nTPM]":"22.9","Tissue RNA - salivary gland [nTPM]":"28.4","Tissue RNA - seminal vesicle [nTPM]":"17.0","Tissue RNA - skeletal muscle [nTPM]":"37.5","Tissue RNA - skin 1 [nTPM]":"21.2","Tissue RNA - small intestine [nTPM]":"20.0","Tissue RNA - smooth muscle [nTPM]":"18.5","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"21.3","Tissue RNA - stomach 1 [nTPM]":"21.5","Tissue RNA - testis [nTPM]":"37.9","Tissue RNA - thalamus [nTPM]":"15.5","Tissue RNA - thymus [nTPM]":"24.6","Tissue RNA - thyroid gland [nTPM]":"25.9","Tissue RNA - tongue [nTPM]":"32.1","Tissue RNA - tonsil [nTPM]":"21.4","Tissue RNA - urinary bladder [nTPM]":"18.6","Tissue RNA - vagina [nTPM]":"12.4","Tissue RNA - white matter [nTPM]":"21.6","Cell RNA - A-431 [nTPM]":"34.3","Cell RNA - A549 [nTPM]":"30.8","Cell RNA - AF22 [nTPM]":"37.2","Cell RNA - AN3-CA [nTPM]":"38.1","Cell RNA - ASC diff [nTPM]":"51.2","Cell RNA - ASC TERT1 [nTPM]":"44.7","Cell RNA - BEWO [nTPM]":"44.1","Cell RNA - BJ [nTPM]":"37.9","Cell RNA - BJ hTERT+ [nTPM]":"36.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.0","Cell RNA - CACO-2 [nTPM]":"30.6","Cell RNA - CAPAN-2 [nTPM]":"29.6","Cell RNA - Daudi [nTPM]":"20.1","Cell RNA - EFO-21 [nTPM]":"9.3","Cell RNA - fHDF\/TERT166 [nTPM]":"33.5","Cell RNA - GAMG [nTPM]":"59.8","Cell RNA - HaCaT [nTPM]":"36.6","Cell RNA - HAP1 [nTPM]":"44.2","Cell RNA - HBEC3-KT [nTPM]":"34.7","Cell RNA - HBF TERT88 [nTPM]":"41.2","Cell RNA - HDLM-2 [nTPM]":"49.4","Cell RNA - HEK 293 [nTPM]":"32.1","Cell RNA - HEL [nTPM]":"71.6","Cell RNA - HeLa [nTPM]":"30.5","Cell RNA - Hep G2 [nTPM]":"46.9","Cell RNA - HHSteC [nTPM]":"36.7","Cell RNA - HL-60 [nTPM]":"61.3","Cell RNA - HMC-1 [nTPM]":"44.9","Cell RNA - HSkMC [nTPM]":"31.1","Cell RNA - hTCEpi [nTPM]":"34.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.1","Cell RNA - hTERT-HME1 [nTPM]":"59.2","Cell RNA - hTERT-RPE1 [nTPM]":"33.6","Cell RNA - HUVEC TERT2 [nTPM]":"34.9","Cell RNA - JURKAT [nTPM]":"33.5","Cell RNA - K-562 [nTPM]":"72.8","Cell RNA - Karpas-707 [nTPM]":"24.2","Cell RNA - LHCN-M2 [nTPM]":"33.1","Cell RNA - MCF7 [nTPM]":"36.5","Cell RNA - MOLT-4 [nTPM]":"40.7","Cell RNA - NB-4 [nTPM]":"24.3","Cell RNA - NTERA-2 [nTPM]":"37.5","Cell RNA - OE19 [nTPM]":"29.8","Cell RNA - PC-3 [nTPM]":"25.7","Cell RNA - REH [nTPM]":"38.7","Cell RNA - RH-30 [nTPM]":"74.5","Cell RNA - RPMI-8226 [nTPM]":"27.8","Cell RNA - RPTEC TERT1 [nTPM]":"28.6","Cell RNA - RT4 [nTPM]":"51.8","Cell RNA - SCLC-21H [nTPM]":"33.4","Cell RNA - SH-SY5Y [nTPM]":"27.5","Cell RNA - SiHa [nTPM]":"41.8","Cell RNA - SK-BR-3 [nTPM]":"30.5","Cell RNA - SK-MEL-30 [nTPM]":"37.7","Cell RNA - SuSa [nTPM]":"32.9","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"40.1","Cell RNA - TIME [nTPM]":"53.1","Cell RNA - U-138 MG [nTPM]":"33.6","Cell RNA - U-2 OS [nTPM]":"28.6","Cell RNA - U-2197 [nTPM]":"34.1","Cell RNA - U-251 MG [nTPM]":"29.6","Cell RNA - U-266\/70 [nTPM]":"47.6","Cell RNA - U-266\/84 [nTPM]":"26.1","Cell RNA - U-698 [nTPM]":"40.3","Cell RNA - U-87 MG [nTPM]":"31.6","Cell RNA - U-937 [nTPM]":"35.0","Cell RNA - WM-115 [nTPM]":"31.3","Blood RNA - basophil [nTPM]":"39.2","Blood RNA - classical monocyte [nTPM]":"10.7","Blood RNA - eosinophil [nTPM]":"13.1","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"7.8","Blood RNA - MAIT T-cell [nTPM]":"10.5","Blood RNA - memory B-cell [nTPM]":"6.1","Blood RNA - memory CD4 T-cell [nTPM]":"7.1","Blood RNA - memory CD8 T-cell [nTPM]":"7.9","Blood RNA - myeloid DC [nTPM]":"11.2","Blood RNA - naive B-cell [nTPM]":"10.6","Blood RNA - naive CD4 T-cell [nTPM]":"8.5","Blood RNA - naive CD8 T-cell [nTPM]":"7.9","Blood RNA - neutrophil [nTPM]":"13.7","Blood RNA - NK-cell [nTPM]":"13.4","Blood RNA - non-classical monocyte [nTPM]":"18.9","Blood RNA - plasmacytoid DC [nTPM]":"8.3","Blood RNA - T-reg [nTPM]":"10.7","Blood RNA - total PBMC [nTPM]":"6.4","Brain RNA - amygdala [nTPM]":"13.5","Brain RNA - basal ganglia [nTPM]":"17.2","Brain RNA - cerebellum [nTPM]":"23.5","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"13.5","Brain RNA - hypothalamus [nTPM]":"18.5","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"15.9","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"15.5","Brain RNA - white matter [nTPM]":"21.6","Single Cell Type RNA - Adipocytes [nTPM]":"31.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"68.4","Single Cell Type RNA - Astrocytes [nTPM]":"98.2","Single Cell Type RNA - B-cells [nTPM]":"26.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"50.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"85.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"50.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.2","Single Cell Type RNA - dendritic cells [nTPM]":"28.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"31.1","Single Cell Type RNA - Early spermatids [nTPM]":"333.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.5","Single Cell Type RNA - Endothelial cells [nTPM]":"36.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"41.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"105.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.0","Single Cell Type RNA - Fibroblasts [nTPM]":"36.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.0","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"35.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"28.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.5","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"131.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.9","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"29.3","Single Cell Type RNA - Langerhans cells [nTPM]":"12.1","Single Cell Type RNA - Late spermatids [nTPM]":"563.9","Single Cell Type RNA - Leydig cells [nTPM]":"37.6","Single Cell Type RNA - Macrophages [nTPM]":"31.8","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"98.4","Single Cell Type RNA - monocytes [nTPM]":"32.9","Single Cell Type RNA - Muller glia cells [nTPM]":"38.8","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"116.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"171.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.2","Single Cell Type RNA - Paneth cells [nTPM]":"15.0","Single Cell Type RNA - Peritubular cells [nTPM]":"36.9","Single Cell Type RNA - Plasma cells [nTPM]":"39.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"43.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"55.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.0","Single Cell Type RNA - Spermatocytes [nTPM]":"128.4","Single Cell Type RNA - Spermatogonia [nTPM]":"93.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"73.2","Single Cell Type RNA - T-cells [nTPM]":"28.8","Single Cell Type RNA - Theca cells [nTPM]":"46.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.3","Single Cell Type RNA - Urothelial cells [nTPM]":"37.4"},{"Gene":"GIPC3","Gene synonym":["C19orf64","DFNB15","DFNB72","DFNB95"],"Ensembl":"ENSG00000179855","Gene description":"GIPC PDZ domain containing family member 3","Uniprot":["Q8TF64"],"Chromosome":"19","Position":"3585478-3593541","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"16.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"10.4","Endothelial cells":"6.2","Hepatic stellate cells":"12.8","Rod photoreceptor cells":"19.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"19.0","HMC-1":"11.8","THP-1":"23.1","WM-115":"44.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067765"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Golgi apparatus"],"Antibody RRID":{"HPA067765":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.6","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"1.4","Tissue RNA - lung [nTPM]":"3.8","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"1.6","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"16.7","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"8.3","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"1.9","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"4.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"6.9","Cell RNA - HeLa [nTPM]":"19.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"2.1","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"3.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.2","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"4.7","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"23.1","Cell RNA - TIME [nTPM]":"3.6","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"44.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.6","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"10.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GJA3","Gene synonym":["CX46","CZP3"],"Ensembl":"ENSG00000121743","Gene description":"Gap junction protein alpha 3","Uniprot":["Q9Y6H8"],"Chromosome":"13","Position":"20138255-20161052","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"7.8","parathyroid gland":"4.0","placenta":"2.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"13.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"head and neck cancer":"1.3","melanoma":"3.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"4.4","CAPAN-2":"7.7","HL-60":"6.6","U-266\/84":"4.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014821"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014821":"AB_2669097"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"7.8","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"3.7","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"1.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"7.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"1.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"2.5","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"6.6","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"1.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.7","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.5","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"1.7","Cell RNA - U-266\/84 [nTPM]":"4.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GJA8","Gene synonym":["CAE","CAE1","CX50","CZP1"],"Ensembl":"ENSG00000121634","Gene description":"Gap junction protein alpha 8","Uniprot":["P48165"],"Chromosome":"1","Position":"147902795-147909269","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"46","RNA tissue specific nTPM":{"testis":"5.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"14.6","Spermatocytes":"39.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014715","HPA062940"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014715":"AB_2732411","HPA062940":"AB_2732693"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"14.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"39.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GJB1","Gene synonym":["CMTX","CMTX1","CX32"],"Ensembl":"ENSG00000169562","Gene description":"Gap junction protein beta 1","Uniprot":["P08034"],"Chromosome":"X","Position":"71212811-71225516","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Dejerine-Sottas syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"100.9","liver":"335.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"114.4","Hepatocytes":"286.4","Proximal enterocytes":"118.8","Proximal tubular cells":"68.9","Undifferentiated cells":"66.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"163.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Hep G2":"143.2","SK-MEL-30":"155.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012994"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB012994":"AB_2533228"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.85e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"27.1","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"63.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"76.5","Tissue RNA - cerebral cortex [nTPM]":"37.6","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"33.9","Tissue RNA - duodenum [nTPM]":"44.0","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"22.5","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"27.4","Tissue RNA - gallbladder [nTPM]":"41.5","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"27.3","Tissue RNA - hypothalamus [nTPM]":"40.9","Tissue RNA - kidney [nTPM]":"42.9","Tissue RNA - liver [nTPM]":"335.7","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"90.6","Tissue RNA - midbrain [nTPM]":"64.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"83.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"76.0","Tissue RNA - prostate [nTPM]":"11.6","Tissue RNA - rectum [nTPM]":"23.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"37.7","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"34.4","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"50.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"16.4","Tissue RNA - testis [nTPM]":"10.2","Tissue RNA - thalamus [nTPM]":"56.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"100.9","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"25.5","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"143.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"5.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.1","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"155.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"27.1","Brain RNA - basal ganglia [nTPM]":"63.2","Brain RNA - cerebellum [nTPM]":"76.5","Brain RNA - cerebral cortex [nTPM]":"37.6","Brain RNA - hippocampal formation [nTPM]":"27.3","Brain RNA - hypothalamus [nTPM]":"40.9","Brain RNA - medulla oblongata [nTPM]":"90.6","Brain RNA - midbrain [nTPM]":"64.4","Brain RNA - pons [nTPM]":"76.0","Brain RNA - spinal cord [nTPM]":"50.0","Brain RNA - thalamus [nTPM]":"56.9","Brain RNA - white matter [nTPM]":"100.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"114.4","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"50.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"58.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.0","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"286.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"51.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.3","Single Cell Type RNA - Paneth cells [nTPM]":"53.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"118.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"68.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"66.1","Single Cell Type RNA - Urothelial cells [nTPM]":"2.8"},{"Gene":"GJB2","Gene synonym":["CX26","DFNA3","DFNB1","NSRD1"],"Ensembl":"ENSG00000165474","Gene description":"Gap junction protein beta 2","Uniprot":["P29033"],"Chromosome":"13","Position":"20187463-20192938","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Ectodermal dysplasia","Ichthyosis","Non-syndromic deafness","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"328.1","esophagus":"812.1","vagina":"519.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"69.8","Basal respiratory cells":"237.4","Basal squamous epithelial cells":"55.8","Ionocytes":"50.8","Squamous epithelial cells":"160.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"447.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"CAPAN-2":"144.6","hTCEpi":"105.4","OE19":"76.9","RT4":"169.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013093","HPA014362"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB013093":"AB_2533903","HPA014362":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.45e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.25e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"3.7","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"328.1","Tissue RNA - choroid plexus [nTPM]":"5.3","Tissue RNA - colon [nTPM]":"20.8","Tissue RNA - duodenum [nTPM]":"12.9","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"812.1","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"9.8","Tissue RNA - liver [nTPM]":"47.5","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"17.4","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"145.2","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"73.0","Tissue RNA - small intestine [nTPM]":"10.6","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"7.6","Tissue RNA - thymus [nTPM]":"12.5","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"90.4","Tissue RNA - urinary bladder [nTPM]":"27.9","Tissue RNA - vagina [nTPM]":"519.8","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"2.9","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"144.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"1.1","Cell RNA - HaCaT [nTPM]":"28.9","Cell RNA - HAP1 [nTPM]":"5.3","Cell RNA - HBEC3-KT [nTPM]":"14.4","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"12.6","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"5.1","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"105.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"19.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"10.7","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"1.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"76.9","Cell RNA - PC-3 [nTPM]":"14.4","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"8.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"169.9","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"2.5","Cell RNA - U-251 MG [nTPM]":"22.2","Cell RNA - U-266\/70 [nTPM]":"8.7","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"7.6","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"69.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"237.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"55.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"37.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"25.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.1","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"13.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.2","Single Cell Type RNA - Paneth cells [nTPM]":"13.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"160.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.0","Single Cell Type RNA - Urothelial cells [nTPM]":"21.7"},{"Gene":"GJB3","Gene synonym":["CX31","DFNA2","EKV"],"Ensembl":"ENSG00000188910","Gene description":"Gap junction protein beta 3","Uniprot":["O75712"],"Chromosome":"1","Position":"34781214-34786369","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"esophagus":"77.8","skin 1":"145.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Basal keratinocytes":"138.4","Basal prostatic cells":"71.9","Basal respiratory cells":"43.6","Pancreatic endocrine cells":"119.8","Prostatic glandular cells":"63.4","Squamous epithelial cells":"91.9","Suprabasal keratinocytes":"170.6","Urothelial cells":"171.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"58.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"88.8","CAPAN-2":"121.7","HaCaT":"99.4","HBEC3-KT":"84.9","hTCEpi":"136.8","OE19":"54.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074472"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Vesicles","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA074472":"AB_2686694"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"8.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"77.8","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"8.9","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"145.0","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"26.4","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"88.8","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"121.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"11.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"99.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"84.9","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"5.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"136.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"35.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"4.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"54.2","Cell RNA - PC-3 [nTPM]":"22.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"40.8","Cell RNA - RT4 [nTPM]":"33.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"13.1","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"5.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"138.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"71.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"15.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"14.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"12.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"119.8","Single Cell Type RNA - Paneth cells [nTPM]":"8.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"63.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"91.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"170.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.1","Single Cell Type RNA - Urothelial cells [nTPM]":"171.0"},{"Gene":"GJB6","Gene synonym":["CX30","DFNA3","ED2","EDH","HED"],"Ensembl":"ENSG00000121742","Gene description":"Gap junction protein beta 6","Uniprot":["O95452"],"Chromosome":"13","Position":"20221962-20232365","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Ectodermal dysplasia","Non-syndromic deafness","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"95.6","esophagus":"195.4","vagina":"139.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"58.8","Basal keratinocytes":"12.2","Basal respiratory cells":"15.6","Ionocytes":"12.2","Squamous epithelial cells":"31.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"145.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"2.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"2.6"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"RT4":"186.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014846"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA014846":"AB_1847135"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"55.8","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"59.4","Tissue RNA - bone marrow [nTPM]":"95.6","Tissue RNA - breast [nTPM]":"3.8","Tissue RNA - cerebellum [nTPM]":"73.0","Tissue RNA - cerebral cortex [nTPM]":"80.9","Tissue RNA - cervix [nTPM]":"65.9","Tissue RNA - choroid plexus [nTPM]":"36.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"195.4","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"50.2","Tissue RNA - hypothalamus [nTPM]":"63.5","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"60.0","Tissue RNA - midbrain [nTPM]":"71.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"4.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"57.5","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"34.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"56.8","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"47.7","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"76.3","Tissue RNA - thymus [nTPM]":"37.6","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"15.4","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"139.3","Tissue RNA - white matter [nTPM]":"42.7","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"12.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"4.0","Cell RNA - HAP1 [nTPM]":"3.5","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"19.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"3.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"186.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"55.8","Brain RNA - basal ganglia [nTPM]":"59.4","Brain RNA - cerebellum [nTPM]":"73.0","Brain RNA - cerebral cortex [nTPM]":"80.9","Brain RNA - hippocampal formation [nTPM]":"50.2","Brain RNA - hypothalamus [nTPM]":"63.5","Brain RNA - medulla oblongata [nTPM]":"60.0","Brain RNA - midbrain [nTPM]":"71.8","Brain RNA - pons [nTPM]":"57.5","Brain RNA - spinal cord [nTPM]":"47.7","Brain RNA - thalamus [nTPM]":"76.3","Brain RNA - white matter [nTPM]":"42.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"58.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.4"},{"Gene":"GJC2","Gene synonym":["CX46.6","CX47","GJA12","SPG44"],"Ensembl":"ENSG00000198835","Gene description":"Gap junction protein gamma 2","Uniprot":["Q5T442"],"Chromosome":"1","Position":"228149930-228159826","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Leukodystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"51.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"12.5","Oligodendrocytes":"26.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"5.4","SCLC-21H":"2.9","TIME":"2.7"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"105.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069619"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA069619":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.9","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"13.6","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"31.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"39.0","Tissue RNA - cerebral cortex [nTPM]":"20.2","Tissue RNA - cervix [nTPM]":"4.2","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"5.8","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"4.7","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"1.7","Tissue RNA - hippocampal formation [nTPM]":"13.9","Tissue RNA - hypothalamus [nTPM]":"19.5","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"43.9","Tissue RNA - midbrain [nTPM]":"31.6","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"38.1","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"1.7","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"28.1","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"27.6","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"51.3","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"5.4","Cell RNA - fHDF\/TERT166 [nTPM]":"1.5","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"1.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.9","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"2.7","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"2.1","Cell RNA - U-2197 [nTPM]":"2.5","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.6","Brain RNA - basal ganglia [nTPM]":"31.2","Brain RNA - cerebellum [nTPM]":"39.0","Brain RNA - cerebral cortex [nTPM]":"20.2","Brain RNA - hippocampal formation [nTPM]":"13.9","Brain RNA - hypothalamus [nTPM]":"19.5","Brain RNA - medulla oblongata [nTPM]":"43.9","Brain RNA - midbrain [nTPM]":"31.6","Brain RNA - pons [nTPM]":"38.1","Brain RNA - spinal cord [nTPM]":"28.1","Brain RNA - thalamus [nTPM]":"27.6","Brain RNA - white matter [nTPM]":"51.3","Single Cell Type RNA - Adipocytes [nTPM]":"2.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"GLE1","Gene synonym":["GLE1L","hGLE1","LCCS1"],"Ensembl":"ENSG00000119392","Gene description":"GLE1 RNA export mediator","Uniprot":["Q53GS7"],"Chromosome":"9","Position":"128504719-128542288","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"77.0","Late spermatids":"58.1","Spermatocytes":"51.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041689","HPA043538","HPA061560"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA041689":"AB_2677617","HPA043538":"AB_2678539","HPA061560":"AB_2684560"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.49e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.04e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"14.0","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"15.7","Tissue RNA - basal ganglia [nTPM]":"9.2","Tissue RNA - bone marrow [nTPM]":"15.1","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"12.4","Tissue RNA - cerebral cortex [nTPM]":"11.3","Tissue RNA - cervix [nTPM]":"13.0","Tissue RNA - choroid plexus [nTPM]":"13.4","Tissue RNA - colon [nTPM]":"17.4","Tissue RNA - duodenum [nTPM]":"16.2","Tissue RNA - endometrium 1 [nTPM]":"11.6","Tissue RNA - epididymis [nTPM]":"10.8","Tissue RNA - esophagus [nTPM]":"16.4","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"14.9","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"8.8","Tissue RNA - kidney [nTPM]":"14.1","Tissue RNA - liver [nTPM]":"16.3","Tissue RNA - lung [nTPM]":"12.3","Tissue RNA - lymph node [nTPM]":"20.4","Tissue RNA - medulla oblongata [nTPM]":"8.7","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"16.2","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"17.6","Tissue RNA - pituitary gland [nTPM]":"14.1","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"18.3","Tissue RNA - retina [nTPM]":"16.5","Tissue RNA - salivary gland [nTPM]":"11.1","Tissue RNA - seminal vesicle [nTPM]":"12.4","Tissue RNA - skeletal muscle [nTPM]":"22.5","Tissue RNA - skin 1 [nTPM]":"19.1","Tissue RNA - small intestine [nTPM]":"15.8","Tissue RNA - smooth muscle [nTPM]":"12.9","Tissue RNA - spinal cord [nTPM]":"8.4","Tissue RNA - spleen [nTPM]":"15.2","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"32.0","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"25.9","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"12.4","Tissue RNA - tonsil [nTPM]":"22.2","Tissue RNA - urinary bladder [nTPM]":"12.8","Tissue RNA - vagina [nTPM]":"12.3","Tissue RNA - white matter [nTPM]":"8.9","Cell RNA - A-431 [nTPM]":"29.6","Cell RNA - A549 [nTPM]":"54.5","Cell RNA - AF22 [nTPM]":"26.2","Cell RNA - AN3-CA [nTPM]":"44.9","Cell RNA - ASC diff [nTPM]":"25.3","Cell RNA - ASC TERT1 [nTPM]":"25.5","Cell RNA - BEWO [nTPM]":"34.6","Cell RNA - BJ [nTPM]":"29.2","Cell RNA - BJ hTERT+ [nTPM]":"24.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.4","Cell RNA - CACO-2 [nTPM]":"36.8","Cell RNA - CAPAN-2 [nTPM]":"20.1","Cell RNA - Daudi [nTPM]":"59.6","Cell RNA - EFO-21 [nTPM]":"23.0","Cell RNA - fHDF\/TERT166 [nTPM]":"33.0","Cell RNA - GAMG [nTPM]":"38.6","Cell RNA - HaCaT [nTPM]":"101.4","Cell RNA - HAP1 [nTPM]":"45.9","Cell RNA - HBEC3-KT [nTPM]":"41.7","Cell RNA - HBF TERT88 [nTPM]":"34.5","Cell RNA - HDLM-2 [nTPM]":"56.9","Cell RNA - HEK 293 [nTPM]":"29.8","Cell RNA - HEL [nTPM]":"30.6","Cell RNA - HeLa [nTPM]":"57.8","Cell RNA - Hep G2 [nTPM]":"34.6","Cell RNA - HHSteC [nTPM]":"28.5","Cell RNA - HL-60 [nTPM]":"49.9","Cell RNA - HMC-1 [nTPM]":"38.8","Cell RNA - HSkMC [nTPM]":"18.1","Cell RNA - hTCEpi [nTPM]":"39.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.6","Cell RNA - hTERT-HME1 [nTPM]":"48.5","Cell RNA - hTERT-RPE1 [nTPM]":"22.3","Cell RNA - HUVEC TERT2 [nTPM]":"22.9","Cell RNA - JURKAT [nTPM]":"54.7","Cell RNA - K-562 [nTPM]":"44.7","Cell RNA - Karpas-707 [nTPM]":"51.0","Cell RNA - LHCN-M2 [nTPM]":"46.7","Cell RNA - MCF7 [nTPM]":"68.6","Cell RNA - MOLT-4 [nTPM]":"49.5","Cell RNA - NB-4 [nTPM]":"35.2","Cell RNA - NTERA-2 [nTPM]":"22.2","Cell RNA - OE19 [nTPM]":"79.1","Cell RNA - PC-3 [nTPM]":"46.7","Cell RNA - REH [nTPM]":"49.8","Cell RNA - RH-30 [nTPM]":"64.2","Cell RNA - RPMI-8226 [nTPM]":"79.0","Cell RNA - RPTEC TERT1 [nTPM]":"27.3","Cell RNA - RT4 [nTPM]":"26.1","Cell RNA - SCLC-21H [nTPM]":"30.9","Cell RNA - SH-SY5Y [nTPM]":"23.1","Cell RNA - SiHa [nTPM]":"71.3","Cell RNA - SK-BR-3 [nTPM]":"42.7","Cell RNA - SK-MEL-30 [nTPM]":"25.9","Cell RNA - SuSa [nTPM]":"21.1","Cell RNA - T-47d [nTPM]":"78.9","Cell RNA - THP-1 [nTPM]":"34.9","Cell RNA - TIME [nTPM]":"17.0","Cell RNA - U-138 MG [nTPM]":"42.5","Cell RNA - U-2 OS [nTPM]":"28.1","Cell RNA - U-2197 [nTPM]":"50.2","Cell RNA - U-251 MG [nTPM]":"41.2","Cell RNA - U-266\/70 [nTPM]":"50.9","Cell RNA - U-266\/84 [nTPM]":"131.9","Cell RNA - U-698 [nTPM]":"45.9","Cell RNA - U-87 MG [nTPM]":"39.9","Cell RNA - U-937 [nTPM]":"37.5","Cell RNA - WM-115 [nTPM]":"46.8","Blood RNA - basophil [nTPM]":"40.0","Blood RNA - classical monocyte [nTPM]":"21.1","Blood RNA - eosinophil [nTPM]":"24.4","Blood RNA - gdT-cell [nTPM]":"22.1","Blood RNA - intermediate monocyte [nTPM]":"26.0","Blood RNA - MAIT T-cell [nTPM]":"18.1","Blood RNA - memory B-cell [nTPM]":"13.4","Blood RNA - memory CD4 T-cell [nTPM]":"17.2","Blood RNA - memory CD8 T-cell [nTPM]":"20.0","Blood RNA - myeloid DC [nTPM]":"22.1","Blood RNA - naive B-cell [nTPM]":"20.5","Blood RNA - naive CD4 T-cell [nTPM]":"15.2","Blood RNA - naive CD8 T-cell [nTPM]":"17.7","Blood RNA - neutrophil [nTPM]":"18.0","Blood RNA - NK-cell [nTPM]":"27.4","Blood RNA - non-classical monocyte [nTPM]":"27.5","Blood RNA - plasmacytoid DC [nTPM]":"13.0","Blood RNA - T-reg [nTPM]":"22.3","Blood RNA - total PBMC [nTPM]":"19.8","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"9.2","Brain RNA - cerebellum [nTPM]":"12.4","Brain RNA - cerebral cortex [nTPM]":"11.3","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"8.8","Brain RNA - medulla oblongata [nTPM]":"8.7","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"8.4","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"8.9","Single Cell Type RNA - Adipocytes [nTPM]":"4.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.0","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"11.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"7.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"77.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.7","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.4","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"14.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.7","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.1","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"58.1","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"20.0","Single Cell Type RNA - Muller glia cells [nTPM]":"8.9","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.3","Single Cell Type RNA - Paneth cells [nTPM]":"8.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.3","Single Cell Type RNA - Spermatocytes [nTPM]":"51.3","Single Cell Type RNA - Spermatogonia [nTPM]":"25.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.3","Single Cell Type RNA - T-cells [nTPM]":"12.1","Single Cell Type RNA - Theca cells [nTPM]":"7.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.1","Single Cell Type RNA - Urothelial cells [nTPM]":"5.4"},{"Gene":"GLRA1","Gene synonym":["STHE"],"Ensembl":"ENSG00000145888","Gene description":"Glycine receptor alpha 1","Uniprot":["P23415"],"Chromosome":"5","Position":"151822513-151924851","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"brain":"40.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"7.4","Excitatory neurons":"1.7","Horizontal cells":"1.7","Inhibitory neurons":"5.0","Oligodendrocyte precursor cells":"1.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"hypothalamus":"9.4","midbrain":"15.1","pons and medulla":"26.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB079042"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079042":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"12.2","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"40.7","Tissue RNA - midbrain [nTPM]":"13.9","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"31.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"20.9","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"12.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"10.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"12.2","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"40.7","Brain RNA - midbrain [nTPM]":"13.9","Brain RNA - pons [nTPM]":"31.4","Brain RNA - spinal cord [nTPM]":"20.9","Brain RNA - thalamus [nTPM]":"12.1","Brain RNA - white matter [nTPM]":"10.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"7.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"GLRB","Gene synonym":[],"Ensembl":"ENSG00000109738","Gene description":"Glycine receptor beta","Uniprot":["P48167"],"Chromosome":"4","Position":"157076125-157172090","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.5","parathyroid gland":"33.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"168.6","Inhibitory neurons":"110.7","Oligodendrocyte precursor cells":"110.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"28.6","hTERT-RPE1":"37.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052363"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052363":"AB_2681800"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"17.7","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"7.4","Tissue RNA - cerebral cortex [nTPM]":"35.5","Tissue RNA - cervix [nTPM]":"9.0","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"3.3","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"18.0","Tissue RNA - hypothalamus [nTPM]":"12.9","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"6.9","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"33.0","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"10.8","Tissue RNA - prostate [nTPM]":"6.2","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"19.5","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"5.7","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"9.8","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"4.9","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"13.5","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"3.4","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"28.6","Cell RNA - ASC diff [nTPM]":"18.0","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"16.0","Cell RNA - BJ hTERT+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"24.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"16.2","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"7.2","Cell RNA - HBEC3-KT [nTPM]":"2.5","Cell RNA - HBF TERT88 [nTPM]":"14.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"9.7","Cell RNA - HEL [nTPM]":"5.0","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"6.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"6.4","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.4","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"37.8","Cell RNA - HUVEC TERT2 [nTPM]":"6.9","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"14.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"13.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"20.6","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"10.3","Cell RNA - SH-SY5Y [nTPM]":"6.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"7.3","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"6.8","Cell RNA - THP-1 [nTPM]":"1.6","Cell RNA - TIME [nTPM]":"10.5","Cell RNA - U-138 MG [nTPM]":"4.5","Cell RNA - U-2 OS [nTPM]":"13.2","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"15.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"10.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"17.7","Brain RNA - cerebellum [nTPM]":"7.4","Brain RNA - cerebral cortex [nTPM]":"35.5","Brain RNA - hippocampal formation [nTPM]":"18.0","Brain RNA - hypothalamus [nTPM]":"12.9","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"6.9","Brain RNA - pons [nTPM]":"10.8","Brain RNA - spinal cord [nTPM]":"5.7","Brain RNA - thalamus [nTPM]":"9.8","Brain RNA - white matter [nTPM]":"13.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"10.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"168.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"110.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"110.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"GLS","Gene synonym":["GLS1","KIAA0838"],"Ensembl":"ENSG00000115419","Gene description":"Glutaminase","Uniprot":["O94925"],"Chromosome":"2","Position":"190880821-190965552","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cataract","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"316.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"391.8","Excitatory neurons":"427.1","Proximal tubular cells":"539.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"907.3","RPTEC TERT1":"419.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036223"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"92000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA036223":"AB_10669984"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"37.0","Tissue RNA - adrenal gland [nTPM]":"77.4","Tissue RNA - amygdala [nTPM]":"38.5","Tissue RNA - appendix [nTPM]":"45.7","Tissue RNA - basal ganglia [nTPM]":"50.5","Tissue RNA - bone marrow [nTPM]":"28.7","Tissue RNA - breast [nTPM]":"32.0","Tissue RNA - cerebellum [nTPM]":"40.5","Tissue RNA - cerebral cortex [nTPM]":"74.6","Tissue RNA - cervix [nTPM]":"31.0","Tissue RNA - choroid plexus [nTPM]":"35.6","Tissue RNA - colon [nTPM]":"32.0","Tissue RNA - duodenum [nTPM]":"92.2","Tissue RNA - endometrium 1 [nTPM]":"28.8","Tissue RNA - epididymis [nTPM]":"26.6","Tissue RNA - esophagus [nTPM]":"16.8","Tissue RNA - fallopian tube [nTPM]":"25.1","Tissue RNA - gallbladder [nTPM]":"41.8","Tissue RNA - heart muscle [nTPM]":"34.7","Tissue RNA - hippocampal formation [nTPM]":"55.5","Tissue RNA - hypothalamus [nTPM]":"35.9","Tissue RNA - kidney [nTPM]":"316.8","Tissue RNA - liver [nTPM]":"11.7","Tissue RNA - lung [nTPM]":"55.6","Tissue RNA - lymph node [nTPM]":"68.0","Tissue RNA - medulla oblongata [nTPM]":"44.7","Tissue RNA - midbrain [nTPM]":"19.8","Tissue RNA - ovary [nTPM]":"28.9","Tissue RNA - pancreas [nTPM]":"36.9","Tissue RNA - parathyroid gland [nTPM]":"62.0","Tissue RNA - pituitary gland [nTPM]":"19.9","Tissue RNA - placenta [nTPM]":"35.8","Tissue RNA - pons [nTPM]":"52.5","Tissue RNA - prostate [nTPM]":"20.8","Tissue RNA - rectum [nTPM]":"30.1","Tissue RNA - retina [nTPM]":"81.8","Tissue RNA - salivary gland [nTPM]":"20.4","Tissue RNA - seminal vesicle [nTPM]":"31.2","Tissue RNA - skeletal muscle [nTPM]":"15.8","Tissue RNA - skin 1 [nTPM]":"28.5","Tissue RNA - small intestine [nTPM]":"103.4","Tissue RNA - smooth muscle [nTPM]":"36.9","Tissue RNA - spinal cord [nTPM]":"12.0","Tissue RNA - spleen [nTPM]":"49.3","Tissue RNA - stomach 1 [nTPM]":"18.7","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"24.1","Tissue RNA - thymus [nTPM]":"41.7","Tissue RNA - thyroid gland [nTPM]":"35.7","Tissue RNA - tongue [nTPM]":"23.6","Tissue RNA - tonsil [nTPM]":"57.9","Tissue RNA - urinary bladder [nTPM]":"36.5","Tissue RNA - vagina [nTPM]":"23.6","Tissue RNA - white matter [nTPM]":"44.8","Cell RNA - A-431 [nTPM]":"43.6","Cell RNA - A549 [nTPM]":"47.2","Cell RNA - AF22 [nTPM]":"32.4","Cell RNA - AN3-CA [nTPM]":"43.1","Cell RNA - ASC diff [nTPM]":"99.7","Cell RNA - ASC TERT1 [nTPM]":"68.9","Cell RNA - BEWO [nTPM]":"84.0","Cell RNA - BJ [nTPM]":"126.8","Cell RNA - BJ hTERT+ [nTPM]":"95.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"90.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"103.1","Cell RNA - CACO-2 [nTPM]":"58.1","Cell RNA - CAPAN-2 [nTPM]":"42.1","Cell RNA - Daudi [nTPM]":"88.5","Cell RNA - EFO-21 [nTPM]":"907.3","Cell RNA - fHDF\/TERT166 [nTPM]":"269.3","Cell RNA - GAMG [nTPM]":"46.1","Cell RNA - HaCaT [nTPM]":"55.6","Cell RNA - HAP1 [nTPM]":"58.0","Cell RNA - HBEC3-KT [nTPM]":"50.0","Cell RNA - HBF TERT88 [nTPM]":"131.5","Cell RNA - HDLM-2 [nTPM]":"219.8","Cell RNA - HEK 293 [nTPM]":"37.7","Cell RNA - HEL [nTPM]":"147.3","Cell RNA - HeLa [nTPM]":"69.1","Cell RNA - Hep G2 [nTPM]":"72.2","Cell RNA - HHSteC [nTPM]":"90.8","Cell RNA - HL-60 [nTPM]":"87.2","Cell RNA - HMC-1 [nTPM]":"66.5","Cell RNA - HSkMC [nTPM]":"62.9","Cell RNA - hTCEpi [nTPM]":"51.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"71.2","Cell RNA - hTERT-HME1 [nTPM]":"48.4","Cell RNA - hTERT-RPE1 [nTPM]":"90.1","Cell RNA - HUVEC TERT2 [nTPM]":"119.3","Cell RNA - JURKAT [nTPM]":"36.7","Cell RNA - K-562 [nTPM]":"69.3","Cell RNA - Karpas-707 [nTPM]":"175.2","Cell RNA - LHCN-M2 [nTPM]":"203.3","Cell RNA - MCF7 [nTPM]":"22.8","Cell RNA - MOLT-4 [nTPM]":"59.2","Cell RNA - NB-4 [nTPM]":"83.7","Cell RNA - NTERA-2 [nTPM]":"86.9","Cell RNA - OE19 [nTPM]":"25.7","Cell RNA - PC-3 [nTPM]":"76.7","Cell RNA - REH [nTPM]":"74.2","Cell RNA - RH-30 [nTPM]":"83.7","Cell RNA - RPMI-8226 [nTPM]":"77.4","Cell RNA - RPTEC TERT1 [nTPM]":"419.2","Cell RNA - RT4 [nTPM]":"78.9","Cell RNA - SCLC-21H [nTPM]":"44.9","Cell RNA - SH-SY5Y [nTPM]":"46.8","Cell RNA - SiHa [nTPM]":"172.8","Cell RNA - SK-BR-3 [nTPM]":"37.9","Cell RNA - SK-MEL-30 [nTPM]":"169.2","Cell RNA - SuSa [nTPM]":"115.1","Cell RNA - T-47d [nTPM]":"14.9","Cell RNA - THP-1 [nTPM]":"53.0","Cell RNA - TIME [nTPM]":"85.3","Cell RNA - U-138 MG [nTPM]":"129.4","Cell RNA - U-2 OS [nTPM]":"94.5","Cell RNA - U-2197 [nTPM]":"65.9","Cell RNA - U-251 MG [nTPM]":"156.8","Cell RNA - U-266\/70 [nTPM]":"56.2","Cell RNA - U-266\/84 [nTPM]":"138.9","Cell RNA - U-698 [nTPM]":"122.1","Cell RNA - U-87 MG [nTPM]":"46.7","Cell RNA - U-937 [nTPM]":"70.6","Cell RNA - WM-115 [nTPM]":"105.5","Blood RNA - basophil [nTPM]":"6.4","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"6.5","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.8","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"3.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"3.6","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"38.5","Brain RNA - basal ganglia [nTPM]":"50.5","Brain RNA - cerebellum [nTPM]":"40.5","Brain RNA - cerebral cortex [nTPM]":"74.6","Brain RNA - hippocampal formation [nTPM]":"55.5","Brain RNA - hypothalamus [nTPM]":"35.9","Brain RNA - medulla oblongata [nTPM]":"44.7","Brain RNA - midbrain [nTPM]":"19.8","Brain RNA - pons [nTPM]":"52.5","Brain RNA - spinal cord [nTPM]":"12.0","Brain RNA - thalamus [nTPM]":"24.1","Brain RNA - white matter [nTPM]":"44.8","Single Cell Type RNA - Adipocytes [nTPM]":"81.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"189.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"122.5","Single Cell Type RNA - Astrocytes [nTPM]":"61.0","Single Cell Type RNA - B-cells [nTPM]":"89.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"174.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"60.9","Single Cell Type RNA - Bipolar cells [nTPM]":"93.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"51.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"28.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"391.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"210.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - dendritic cells [nTPM]":"128.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"100.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"21.4","Single Cell Type RNA - Early spermatids [nTPM]":"6.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"66.8","Single Cell Type RNA - Endothelial cells [nTPM]":"68.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"59.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"427.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.6","Single Cell Type RNA - Fibroblasts [nTPM]":"66.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"97.9","Single Cell Type RNA - granulocytes [nTPM]":"36.8","Single Cell Type RNA - Granulosa cells [nTPM]":"48.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.5","Single Cell Type RNA - Hepatocytes [nTPM]":"4.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.1","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"270.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.7","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"31.2","Single Cell Type RNA - Langerhans cells [nTPM]":"230.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"28.6","Single Cell Type RNA - Macrophages [nTPM]":"84.3","Single Cell Type RNA - Melanocytes [nTPM]":"88.9","Single Cell Type RNA - Microglial cells [nTPM]":"143.4","Single Cell Type RNA - monocytes [nTPM]":"68.4","Single Cell Type RNA - Muller glia cells [nTPM]":"11.9","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"163.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"146.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.8","Single Cell Type RNA - Paneth cells [nTPM]":"92.9","Single Cell Type RNA - Peritubular cells [nTPM]":"43.2","Single Cell Type RNA - Plasma cells [nTPM]":"118.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"70.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"165.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"539.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"111.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"71.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"76.0","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"61.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"162.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"114.0","Single Cell Type RNA - Theca cells [nTPM]":"97.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.6","Single Cell Type RNA - Urothelial cells [nTPM]":"56.7"},{"Gene":"GNAL","Gene synonym":[],"Ensembl":"ENSG00000141404","Gene description":"G protein subunit alpha L","Uniprot":["P38405"],"Chromosome":"18","Position":"11689264-11885685","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"99.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"76.9","Inhibitory neurons":"119.5","Oligodendrocyte precursor cells":"58.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"99.0"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"26.4","HeLa":"27.4","U-2 OS":"13.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"14","RNA pig brain regional specific nTPM":{"basal ganglia":"164.1"},"Antibody":["CAB015464","HPA051160"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB015464":"AB_831819","HPA051160":"AB_2732564"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.7","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"29.2","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"99.0","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"4.1","Tissue RNA - cerebellum [nTPM]":"3.5","Tissue RNA - cerebral cortex [nTPM]":"36.7","Tissue RNA - cervix [nTPM]":"7.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"7.1","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"6.6","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"8.0","Tissue RNA - fallopian tube [nTPM]":"3.9","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"3.5","Tissue RNA - hippocampal formation [nTPM]":"39.6","Tissue RNA - hypothalamus [nTPM]":"16.7","Tissue RNA - kidney [nTPM]":"4.0","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"2.7","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"8.9","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"16.3","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"9.3","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"17.0","Tissue RNA - skeletal muscle [nTPM]":"21.7","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"2.9","Tissue RNA - stomach 1 [nTPM]":"3.1","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"14.4","Tissue RNA - thymus [nTPM]":"4.3","Tissue RNA - thyroid gland [nTPM]":"7.8","Tissue RNA - tongue [nTPM]":"13.1","Tissue RNA - tonsil [nTPM]":"5.5","Tissue RNA - urinary bladder [nTPM]":"13.2","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"4.8","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"8.7","Cell RNA - AF22 [nTPM]":"10.3","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"9.2","Cell RNA - CAPAN-2 [nTPM]":"1.6","Cell RNA - Daudi [nTPM]":"26.4","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"5.7","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"9.7","Cell RNA - HBEC3-KT [nTPM]":"8.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"5.6","Cell RNA - HEK 293 [nTPM]":"9.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"27.4","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"11.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"8.4","Cell RNA - OE19 [nTPM]":"7.2","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.6","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"9.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"12.3","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"2.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"1.5","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"13.2","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"2.6","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"29.2","Brain RNA - basal ganglia [nTPM]":"99.0","Brain RNA - cerebellum [nTPM]":"3.5","Brain RNA - cerebral cortex [nTPM]":"36.7","Brain RNA - hippocampal formation [nTPM]":"39.6","Brain RNA - hypothalamus [nTPM]":"16.7","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"8.9","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"14.4","Brain RNA - white matter [nTPM]":"4.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.9","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"7.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"8.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"13.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.6","Single Cell Type RNA - Endothelial cells [nTPM]":"5.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"76.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"3.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"119.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"58.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.9","Single Cell Type RNA - Spermatocytes [nTPM]":"4.3","Single Cell Type RNA - Spermatogonia [nTPM]":"10.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.4","Single Cell Type RNA - Urothelial cells [nTPM]":"15.0"},{"Gene":"GNAO1","Gene synonym":["G-ALPHA-o"],"Ensembl":"ENSG00000087258","Gene description":"G protein subunit alpha o1","Uniprot":["P09471"],"Chromosome":"16","Position":"56191390-56357444","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"171.2","retina":"52.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"135.8","Bipolar cells":"189.2","Excitatory neurons":"138.7","Inhibitory neurons":"132.2","Oligodendrocyte precursor cells":"87.9","Oligodendrocytes":"368.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"11.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"30.7","BJ hTERT+ SV40 Large T+":"20.0","SCLC-21H":"61.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008387","HPA040878"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"510000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB008387":"AB_591430","HPA040878":"AB_2677184"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.93e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-5"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"100.8","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"171.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"55.1","Tissue RNA - cerebral cortex [nTPM]":"121.9","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"34.0","Tissue RNA - duodenum [nTPM]":"3.1","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"34.1","Tissue RNA - hippocampal formation [nTPM]":"101.9","Tissue RNA - hypothalamus [nTPM]":"87.6","Tissue RNA - kidney [nTPM]":"1.1","Tissue RNA - liver [nTPM]":"10.2","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"74.6","Tissue RNA - midbrain [nTPM]":"89.6","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"28.5","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"77.9","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"5.1","Tissue RNA - retina [nTPM]":"52.4","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"7.3","Tissue RNA - smooth muscle [nTPM]":"10.2","Tissue RNA - spinal cord [nTPM]":"44.6","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"11.0","Tissue RNA - testis [nTPM]":"13.8","Tissue RNA - thalamus [nTPM]":"107.3","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"110.3","Cell RNA - A-431 [nTPM]":"7.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"7.6","Cell RNA - BJ hTERT+ [nTPM]":"30.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.5","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"7.3","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"4.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"13.7","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"2.7","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"6.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"11.1","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"61.2","Cell RNA - SH-SY5Y [nTPM]":"12.2","Cell RNA - SiHa [nTPM]":"12.5","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"1.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"100.8","Brain RNA - basal ganglia [nTPM]":"171.2","Brain RNA - cerebellum [nTPM]":"55.1","Brain RNA - cerebral cortex [nTPM]":"121.9","Brain RNA - hippocampal formation [nTPM]":"101.9","Brain RNA - hypothalamus [nTPM]":"87.6","Brain RNA - medulla oblongata [nTPM]":"74.6","Brain RNA - midbrain [nTPM]":"89.6","Brain RNA - pons [nTPM]":"77.9","Brain RNA - spinal cord [nTPM]":"44.6","Brain RNA - thalamus [nTPM]":"107.3","Brain RNA - white matter [nTPM]":"110.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"135.8","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"189.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"4.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"26.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"138.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"10.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"79.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"132.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"53.6","Single Cell Type RNA - Leydig cells [nTPM]":"34.8","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"87.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"368.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"44.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"15.4","Single Cell Type RNA - Spermatogonia [nTPM]":"8.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"GNAT1","Gene synonym":["CSNBAD3"],"Ensembl":"ENSG00000114349","Gene description":"G protein subunit alpha transducin 1","Uniprot":["P11488"],"Chromosome":"3","Position":"50191610-50197696","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Transducer"],"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"904","RNA tissue specific nTPM":{"retina":"1120.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"2275.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"hippocampal formation":"6.5"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045393"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045393":"AB_2679310"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1120.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"222.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"241.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"14.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"13.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"90.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"38.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"397.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2275.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GNAT2","Gene synonym":["ACHM4"],"Ensembl":"ENSG00000134183","Gene description":"G protein subunit alpha transducin 2","Uniprot":["P19087"],"Chromosome":"1","Position":"109603091-109619929","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"retina":"78.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"60.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"2.3","eosinophil":"2.5","neutrophil":"3.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"3.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"4.5","TIME":"5.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"78.8","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"4.5","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"1.3","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"1.2","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.5","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"1.3","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"2.7","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"5.9","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"2.9","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"2.8","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"2.3","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"3.7","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GNB3","Gene synonym":[],"Ensembl":"ENSG00000111664","Gene description":"G protein subunit beta 3","Uniprot":["P16520"],"Chromosome":"12","Position":"6839954-6847393","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"retina":"426.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"471.3","Cone photoreceptor cells":"932.0","Rod photoreceptor cells":"462.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"3.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"14.1","NTERA-2":"17.0","U-698":"40.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"5.1"},"Antibody":["HPA040736"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA040736":"AB_2677106"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"6.7","Tissue RNA - cerebral cortex [nTPM]":"9.5","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"1.6","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"4.4","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"5.7","Tissue RNA - midbrain [nTPM]":"5.3","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"36.2","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"426.5","Tissue RNA - salivary gland [nTPM]":"2.1","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"1.5","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"5.7","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"9.4","Cell RNA - AN3-CA [nTPM]":"3.1","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"2.0","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"4.8","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.1","Cell RNA - CACO-2 [nTPM]":"1.9","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"14.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"5.1","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"9.2","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"2.3","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"3.4","Cell RNA - HeLa [nTPM]":"6.8","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.4","Cell RNA - hTERT-HME1 [nTPM]":"2.7","Cell RNA - hTERT-RPE1 [nTPM]":"9.6","Cell RNA - HUVEC TERT2 [nTPM]":"2.5","Cell RNA - JURKAT [nTPM]":"1.8","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"17.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"2.8","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"2.2","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"1.0","Cell RNA - SuSa [nTPM]":"2.5","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"4.0","Cell RNA - U-138 MG [nTPM]":"3.2","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"4.8","Cell RNA - U-251 MG [nTPM]":"6.7","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"40.9","Cell RNA - U-87 MG [nTPM]":"1.3","Cell RNA - U-937 [nTPM]":"0.7","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"6.7","Brain RNA - cerebral cortex [nTPM]":"9.5","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"5.7","Brain RNA - midbrain [nTPM]":"5.3","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"5.7","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"471.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"932.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"74.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"86.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"462.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"GNB4","Gene synonym":[],"Ensembl":"ENSG00000114450","Gene description":"G protein subunit beta 4","Uniprot":["Q9HAV0"],"Chromosome":"3","Position":"179396088-179451476","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"81.1","Kupffer cells":"98.1","Macrophages":"66.8","Microglial cells":"91.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"143.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018383","CAB018737","HPA040736"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB018383":"AB_631542","CAB018737":"AB_640712","HPA040736":"AB_2677106"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.39e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.9","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"21.9","Tissue RNA - basal ganglia [nTPM]":"19.2","Tissue RNA - bone marrow [nTPM]":"33.7","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"11.2","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"9.5","Tissue RNA - duodenum [nTPM]":"5.9","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"21.9","Tissue RNA - fallopian tube [nTPM]":"7.0","Tissue RNA - gallbladder [nTPM]":"15.2","Tissue RNA - heart muscle [nTPM]":"13.9","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"5.9","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"17.7","Tissue RNA - medulla oblongata [nTPM]":"15.5","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"5.8","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"21.8","Tissue RNA - pons [nTPM]":"14.5","Tissue RNA - prostate [nTPM]":"4.5","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"34.1","Tissue RNA - small intestine [nTPM]":"6.4","Tissue RNA - smooth muscle [nTPM]":"23.5","Tissue RNA - spinal cord [nTPM]":"14.5","Tissue RNA - spleen [nTPM]":"18.1","Tissue RNA - stomach 1 [nTPM]":"7.4","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"7.9","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"5.7","Tissue RNA - tonsil [nTPM]":"11.5","Tissue RNA - urinary bladder [nTPM]":"13.2","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"19.7","Cell RNA - A-431 [nTPM]":"33.4","Cell RNA - A549 [nTPM]":"15.4","Cell RNA - AF22 [nTPM]":"37.7","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"23.8","Cell RNA - ASC TERT1 [nTPM]":"41.5","Cell RNA - BEWO [nTPM]":"44.1","Cell RNA - BJ [nTPM]":"46.7","Cell RNA - BJ hTERT+ [nTPM]":"33.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"54.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"61.3","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"3.7","Cell RNA - Daudi [nTPM]":"61.6","Cell RNA - EFO-21 [nTPM]":"9.9","Cell RNA - fHDF\/TERT166 [nTPM]":"54.3","Cell RNA - GAMG [nTPM]":"49.7","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"36.4","Cell RNA - HBEC3-KT [nTPM]":"43.1","Cell RNA - HBF TERT88 [nTPM]":"56.7","Cell RNA - HDLM-2 [nTPM]":"143.6","Cell RNA - HEK 293 [nTPM]":"29.2","Cell RNA - HEL [nTPM]":"71.3","Cell RNA - HeLa [nTPM]":"54.9","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"23.4","Cell RNA - HL-60 [nTPM]":"62.3","Cell RNA - HMC-1 [nTPM]":"16.2","Cell RNA - HSkMC [nTPM]":"32.9","Cell RNA - hTCEpi [nTPM]":"6.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.4","Cell RNA - hTERT-HME1 [nTPM]":"21.6","Cell RNA - hTERT-RPE1 [nTPM]":"12.0","Cell RNA - HUVEC TERT2 [nTPM]":"59.3","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"18.7","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"42.8","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"32.8","Cell RNA - NB-4 [nTPM]":"24.3","Cell RNA - NTERA-2 [nTPM]":"18.9","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"19.3","Cell RNA - REH [nTPM]":"61.4","Cell RNA - RH-30 [nTPM]":"49.2","Cell RNA - RPMI-8226 [nTPM]":"25.3","Cell RNA - RPTEC TERT1 [nTPM]":"34.9","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"7.0","Cell RNA - SH-SY5Y [nTPM]":"20.5","Cell RNA - SiHa [nTPM]":"37.5","Cell RNA - SK-BR-3 [nTPM]":"33.0","Cell RNA - SK-MEL-30 [nTPM]":"61.1","Cell RNA - SuSa [nTPM]":"23.0","Cell RNA - T-47d [nTPM]":"67.5","Cell RNA - THP-1 [nTPM]":"26.1","Cell RNA - TIME [nTPM]":"45.3","Cell RNA - U-138 MG [nTPM]":"45.1","Cell RNA - U-2 OS [nTPM]":"27.4","Cell RNA - U-2197 [nTPM]":"13.6","Cell RNA - U-251 MG [nTPM]":"61.6","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"24.7","Cell RNA - U-937 [nTPM]":"52.8","Cell RNA - WM-115 [nTPM]":"35.4","Blood RNA - basophil [nTPM]":"5.6","Blood RNA - classical monocyte [nTPM]":"21.3","Blood RNA - eosinophil [nTPM]":"11.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"27.8","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"24.9","Blood RNA - naive B-cell [nTPM]":"13.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"14.5","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"23.5","Blood RNA - plasmacytoid DC [nTPM]":"12.8","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"8.8","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"19.2","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"11.2","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"15.5","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"14.5","Brain RNA - spinal cord [nTPM]":"14.5","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"19.7","Single Cell Type RNA - Adipocytes [nTPM]":"40.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"20.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"12.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.9","Single Cell Type RNA - Endothelial cells [nTPM]":"42.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"22.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.7","Single Cell Type RNA - Fibroblasts [nTPM]":"26.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.8","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"16.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"81.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"98.1","Single Cell Type RNA - Langerhans cells [nTPM]":"17.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"66.8","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"91.8","Single Cell Type RNA - monocytes [nTPM]":"59.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"16.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"14.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"GOSR2","Gene synonym":["Bos1","GS27"],"Ensembl":"ENSG00000108433","Gene description":"Golgi SNAP receptor complex member 2","Uniprot":["O14653"],"Chromosome":"17","Position":"46923075-46975524","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"303.0","Late spermatids":"796.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017456","HPA048956","HPA054472"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB017456":"AB_10532285","HPA048956":"AB_2680569","HPA054472":"AB_2682499"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.80e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.2","Tissue RNA - adrenal gland [nTPM]":"25.6","Tissue RNA - amygdala [nTPM]":"28.5","Tissue RNA - appendix [nTPM]":"21.7","Tissue RNA - basal ganglia [nTPM]":"28.7","Tissue RNA - bone marrow [nTPM]":"16.4","Tissue RNA - breast [nTPM]":"24.8","Tissue RNA - cerebellum [nTPM]":"31.6","Tissue RNA - cerebral cortex [nTPM]":"37.6","Tissue RNA - cervix [nTPM]":"24.8","Tissue RNA - choroid plexus [nTPM]":"32.9","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"49.8","Tissue RNA - endometrium 1 [nTPM]":"23.8","Tissue RNA - epididymis [nTPM]":"31.6","Tissue RNA - esophagus [nTPM]":"21.5","Tissue RNA - fallopian tube [nTPM]":"21.3","Tissue RNA - gallbladder [nTPM]":"18.3","Tissue RNA - heart muscle [nTPM]":"32.5","Tissue RNA - hippocampal formation [nTPM]":"29.3","Tissue RNA - hypothalamus [nTPM]":"29.3","Tissue RNA - kidney [nTPM]":"42.2","Tissue RNA - liver [nTPM]":"33.9","Tissue RNA - lung [nTPM]":"23.6","Tissue RNA - lymph node [nTPM]":"26.4","Tissue RNA - medulla oblongata [nTPM]":"28.7","Tissue RNA - midbrain [nTPM]":"29.7","Tissue RNA - ovary [nTPM]":"26.1","Tissue RNA - pancreas [nTPM]":"31.3","Tissue RNA - parathyroid gland [nTPM]":"35.5","Tissue RNA - pituitary gland [nTPM]":"37.1","Tissue RNA - placenta [nTPM]":"28.7","Tissue RNA - pons [nTPM]":"29.2","Tissue RNA - prostate [nTPM]":"23.1","Tissue RNA - rectum [nTPM]":"27.4","Tissue RNA - retina [nTPM]":"25.0","Tissue RNA - salivary gland [nTPM]":"32.5","Tissue RNA - seminal vesicle [nTPM]":"30.5","Tissue RNA - skeletal muscle [nTPM]":"43.1","Tissue RNA - skin 1 [nTPM]":"21.9","Tissue RNA - small intestine [nTPM]":"43.2","Tissue RNA - smooth muscle [nTPM]":"29.8","Tissue RNA - spinal cord [nTPM]":"28.1","Tissue RNA - spleen [nTPM]":"30.1","Tissue RNA - stomach 1 [nTPM]":"23.1","Tissue RNA - testis [nTPM]":"48.3","Tissue RNA - thalamus [nTPM]":"29.5","Tissue RNA - thymus [nTPM]":"27.1","Tissue RNA - thyroid gland [nTPM]":"26.6","Tissue RNA - tongue [nTPM]":"34.3","Tissue RNA - tonsil [nTPM]":"31.8","Tissue RNA - urinary bladder [nTPM]":"25.2","Tissue RNA - vagina [nTPM]":"18.6","Tissue RNA - white matter [nTPM]":"30.9","Cell RNA - A-431 [nTPM]":"44.6","Cell RNA - A549 [nTPM]":"47.2","Cell RNA - AF22 [nTPM]":"33.5","Cell RNA - AN3-CA [nTPM]":"40.3","Cell RNA - ASC diff [nTPM]":"54.9","Cell RNA - ASC TERT1 [nTPM]":"39.3","Cell RNA - BEWO [nTPM]":"37.8","Cell RNA - BJ [nTPM]":"59.7","Cell RNA - BJ hTERT+ [nTPM]":"58.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"63.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.7","Cell RNA - CACO-2 [nTPM]":"60.1","Cell RNA - CAPAN-2 [nTPM]":"25.7","Cell RNA - Daudi [nTPM]":"37.7","Cell RNA - EFO-21 [nTPM]":"33.1","Cell RNA - fHDF\/TERT166 [nTPM]":"75.4","Cell RNA - GAMG [nTPM]":"66.5","Cell RNA - HaCaT [nTPM]":"30.1","Cell RNA - HAP1 [nTPM]":"43.4","Cell RNA - HBEC3-KT [nTPM]":"48.5","Cell RNA - HBF TERT88 [nTPM]":"77.8","Cell RNA - HDLM-2 [nTPM]":"83.0","Cell RNA - HEK 293 [nTPM]":"33.3","Cell RNA - HEL [nTPM]":"56.8","Cell RNA - HeLa [nTPM]":"37.4","Cell RNA - Hep G2 [nTPM]":"60.1","Cell RNA - HHSteC [nTPM]":"60.3","Cell RNA - HL-60 [nTPM]":"44.9","Cell RNA - HMC-1 [nTPM]":"44.1","Cell RNA - HSkMC [nTPM]":"40.8","Cell RNA - hTCEpi [nTPM]":"47.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"52.2","Cell RNA - hTERT-HME1 [nTPM]":"73.2","Cell RNA - hTERT-RPE1 [nTPM]":"49.0","Cell RNA - HUVEC TERT2 [nTPM]":"52.6","Cell RNA - JURKAT [nTPM]":"43.7","Cell RNA - K-562 [nTPM]":"56.5","Cell RNA - Karpas-707 [nTPM]":"50.9","Cell RNA - LHCN-M2 [nTPM]":"46.2","Cell RNA - MCF7 [nTPM]":"46.8","Cell RNA - MOLT-4 [nTPM]":"50.0","Cell RNA - NB-4 [nTPM]":"24.2","Cell RNA - NTERA-2 [nTPM]":"31.1","Cell RNA - OE19 [nTPM]":"60.1","Cell RNA - PC-3 [nTPM]":"65.8","Cell RNA - REH [nTPM]":"43.5","Cell RNA - RH-30 [nTPM]":"64.0","Cell RNA - RPMI-8226 [nTPM]":"44.5","Cell RNA - RPTEC TERT1 [nTPM]":"40.7","Cell RNA - RT4 [nTPM]":"37.7","Cell RNA - SCLC-21H [nTPM]":"28.8","Cell RNA - SH-SY5Y [nTPM]":"61.5","Cell RNA - SiHa [nTPM]":"33.3","Cell RNA - SK-BR-3 [nTPM]":"19.2","Cell RNA - SK-MEL-30 [nTPM]":"47.9","Cell RNA - SuSa [nTPM]":"57.1","Cell RNA - T-47d [nTPM]":"55.1","Cell RNA - THP-1 [nTPM]":"31.3","Cell RNA - TIME [nTPM]":"62.1","Cell RNA - U-138 MG [nTPM]":"60.0","Cell RNA - U-2 OS [nTPM]":"38.8","Cell RNA - U-2197 [nTPM]":"47.4","Cell RNA - U-251 MG [nTPM]":"58.9","Cell RNA - U-266\/70 [nTPM]":"64.6","Cell RNA - U-266\/84 [nTPM]":"39.4","Cell RNA - U-698 [nTPM]":"60.1","Cell RNA - U-87 MG [nTPM]":"56.1","Cell RNA - U-937 [nTPM]":"28.6","Cell RNA - WM-115 [nTPM]":"67.1","Blood RNA - basophil [nTPM]":"39.5","Blood RNA - classical monocyte [nTPM]":"33.1","Blood RNA - eosinophil [nTPM]":"29.2","Blood RNA - gdT-cell [nTPM]":"33.9","Blood RNA - intermediate monocyte [nTPM]":"63.2","Blood RNA - MAIT T-cell [nTPM]":"31.3","Blood RNA - memory B-cell [nTPM]":"29.8","Blood RNA - memory CD4 T-cell [nTPM]":"29.7","Blood RNA - memory CD8 T-cell [nTPM]":"27.8","Blood RNA - myeloid DC [nTPM]":"32.7","Blood RNA - naive B-cell [nTPM]":"38.6","Blood RNA - naive CD4 T-cell [nTPM]":"29.1","Blood RNA - naive CD8 T-cell [nTPM]":"25.4","Blood RNA - neutrophil [nTPM]":"3.6","Blood RNA - NK-cell [nTPM]":"31.2","Blood RNA - non-classical monocyte [nTPM]":"86.0","Blood RNA - plasmacytoid DC [nTPM]":"29.7","Blood RNA - T-reg [nTPM]":"38.8","Blood RNA - total PBMC [nTPM]":"35.2","Brain RNA - amygdala [nTPM]":"28.5","Brain RNA - basal ganglia [nTPM]":"28.7","Brain RNA - cerebellum [nTPM]":"31.6","Brain RNA - cerebral cortex [nTPM]":"37.6","Brain RNA - hippocampal formation [nTPM]":"29.3","Brain RNA - hypothalamus [nTPM]":"29.3","Brain RNA - medulla oblongata [nTPM]":"28.7","Brain RNA - midbrain [nTPM]":"29.7","Brain RNA - pons [nTPM]":"29.2","Brain RNA - spinal cord [nTPM]":"28.1","Brain RNA - thalamus [nTPM]":"29.5","Brain RNA - white matter [nTPM]":"30.9","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.7","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"22.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"18.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"14.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.2","Single Cell Type RNA - dendritic cells [nTPM]":"23.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"34.5","Single Cell Type RNA - Early spermatids [nTPM]":"303.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.0","Single Cell Type RNA - Endothelial cells [nTPM]":"25.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"20.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.1","Single Cell Type RNA - Fibroblasts [nTPM]":"18.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"22.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"22.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.1","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"22.0","Single Cell Type RNA - Langerhans cells [nTPM]":"14.7","Single Cell Type RNA - Late spermatids [nTPM]":"796.1","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"15.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"22.0","Single Cell Type RNA - Muller glia cells [nTPM]":"16.4","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.1","Single Cell Type RNA - Paneth cells [nTPM]":"24.2","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"23.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"96.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"90.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.8","Single Cell Type RNA - Spermatocytes [nTPM]":"33.1","Single Cell Type RNA - Spermatogonia [nTPM]":"26.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.7","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"18.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"20.5"},{"Gene":"GOT2","Gene synonym":["KAT4","KATIV","KYAT4","mitAAT"],"Ensembl":"ENSG00000125166","Gene description":"Glutamic-oxaloacetic transaminase 2","Uniprot":["P00505"],"Chromosome":"16","Position":"58707131-58734342","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"698.4","tongue":"726.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"341.9","Hepatocytes":"176.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018139","HPA058537"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018139":"AB_1849903","HPA058537":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.75e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.6","Tissue RNA - adrenal gland [nTPM]":"73.9","Tissue RNA - amygdala [nTPM]":"52.4","Tissue RNA - appendix [nTPM]":"27.4","Tissue RNA - basal ganglia [nTPM]":"55.9","Tissue RNA - bone marrow [nTPM]":"21.1","Tissue RNA - breast [nTPM]":"36.3","Tissue RNA - cerebellum [nTPM]":"62.5","Tissue RNA - cerebral cortex [nTPM]":"66.9","Tissue RNA - cervix [nTPM]":"34.1","Tissue RNA - choroid plexus [nTPM]":"129.4","Tissue RNA - colon [nTPM]":"57.6","Tissue RNA - duodenum [nTPM]":"37.4","Tissue RNA - endometrium 1 [nTPM]":"36.5","Tissue RNA - epididymis [nTPM]":"66.3","Tissue RNA - esophagus [nTPM]":"66.9","Tissue RNA - fallopian tube [nTPM]":"46.7","Tissue RNA - gallbladder [nTPM]":"24.1","Tissue RNA - heart muscle [nTPM]":"313.2","Tissue RNA - hippocampal formation [nTPM]":"57.9","Tissue RNA - hypothalamus [nTPM]":"59.3","Tissue RNA - kidney [nTPM]":"88.0","Tissue RNA - liver [nTPM]":"321.4","Tissue RNA - lung [nTPM]":"25.2","Tissue RNA - lymph node [nTPM]":"35.6","Tissue RNA - medulla oblongata [nTPM]":"60.6","Tissue RNA - midbrain [nTPM]":"51.0","Tissue RNA - ovary [nTPM]":"29.4","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"98.6","Tissue RNA - pituitary gland [nTPM]":"46.7","Tissue RNA - placenta [nTPM]":"24.7","Tissue RNA - pons [nTPM]":"62.5","Tissue RNA - prostate [nTPM]":"59.0","Tissue RNA - rectum [nTPM]":"65.0","Tissue RNA - retina [nTPM]":"91.4","Tissue RNA - salivary gland [nTPM]":"47.7","Tissue RNA - seminal vesicle [nTPM]":"65.7","Tissue RNA - skeletal muscle [nTPM]":"698.4","Tissue RNA - skin 1 [nTPM]":"41.1","Tissue RNA - small intestine [nTPM]":"35.7","Tissue RNA - smooth muscle [nTPM]":"46.7","Tissue RNA - spinal cord [nTPM]":"50.1","Tissue RNA - spleen [nTPM]":"28.5","Tissue RNA - stomach 1 [nTPM]":"54.9","Tissue RNA - testis [nTPM]":"28.9","Tissue RNA - thalamus [nTPM]":"58.7","Tissue RNA - thymus [nTPM]":"35.9","Tissue RNA - thyroid gland [nTPM]":"42.6","Tissue RNA - tongue [nTPM]":"726.8","Tissue RNA - tonsil [nTPM]":"57.0","Tissue RNA - urinary bladder [nTPM]":"57.0","Tissue RNA - vagina [nTPM]":"45.1","Tissue RNA - white matter [nTPM]":"61.0","Cell RNA - A-431 [nTPM]":"137.2","Cell RNA - A549 [nTPM]":"182.4","Cell RNA - AF22 [nTPM]":"93.8","Cell RNA - AN3-CA [nTPM]":"114.8","Cell RNA - ASC diff [nTPM]":"66.6","Cell RNA - ASC TERT1 [nTPM]":"59.8","Cell RNA - BEWO [nTPM]":"122.0","Cell RNA - BJ [nTPM]":"101.4","Cell RNA - BJ hTERT+ [nTPM]":"108.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"197.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.7","Cell RNA - CACO-2 [nTPM]":"158.9","Cell RNA - CAPAN-2 [nTPM]":"120.1","Cell RNA - Daudi [nTPM]":"302.3","Cell RNA - EFO-21 [nTPM]":"117.3","Cell RNA - fHDF\/TERT166 [nTPM]":"114.6","Cell RNA - GAMG [nTPM]":"86.5","Cell RNA - HaCaT [nTPM]":"195.5","Cell RNA - HAP1 [nTPM]":"203.2","Cell RNA - HBEC3-KT [nTPM]":"199.2","Cell RNA - HBF TERT88 [nTPM]":"250.1","Cell RNA - HDLM-2 [nTPM]":"83.1","Cell RNA - HEK 293 [nTPM]":"182.0","Cell RNA - HEL [nTPM]":"81.4","Cell RNA - HeLa [nTPM]":"92.1","Cell RNA - Hep G2 [nTPM]":"179.3","Cell RNA - HHSteC [nTPM]":"84.2","Cell RNA - HL-60 [nTPM]":"132.3","Cell RNA - HMC-1 [nTPM]":"71.9","Cell RNA - HSkMC [nTPM]":"58.4","Cell RNA - hTCEpi [nTPM]":"110.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"125.2","Cell RNA - hTERT-HME1 [nTPM]":"108.2","Cell RNA - hTERT-RPE1 [nTPM]":"112.4","Cell RNA - HUVEC TERT2 [nTPM]":"201.8","Cell RNA - JURKAT [nTPM]":"141.9","Cell RNA - K-562 [nTPM]":"167.0","Cell RNA - Karpas-707 [nTPM]":"30.6","Cell RNA - LHCN-M2 [nTPM]":"102.2","Cell RNA - MCF7 [nTPM]":"122.5","Cell RNA - MOLT-4 [nTPM]":"164.0","Cell RNA - NB-4 [nTPM]":"128.0","Cell RNA - NTERA-2 [nTPM]":"127.7","Cell RNA - OE19 [nTPM]":"90.8","Cell RNA - PC-3 [nTPM]":"338.0","Cell RNA - REH [nTPM]":"177.8","Cell RNA - RH-30 [nTPM]":"142.7","Cell RNA - RPMI-8226 [nTPM]":"291.1","Cell RNA - RPTEC TERT1 [nTPM]":"187.9","Cell RNA - RT4 [nTPM]":"197.7","Cell RNA - SCLC-21H [nTPM]":"148.2","Cell RNA - SH-SY5Y [nTPM]":"107.6","Cell RNA - SiHa [nTPM]":"195.2","Cell RNA - SK-BR-3 [nTPM]":"208.5","Cell RNA - SK-MEL-30 [nTPM]":"74.8","Cell RNA - SuSa [nTPM]":"84.2","Cell RNA - T-47d [nTPM]":"105.5","Cell RNA - THP-1 [nTPM]":"42.7","Cell RNA - TIME [nTPM]":"82.3","Cell RNA - U-138 MG [nTPM]":"71.4","Cell RNA - U-2 OS [nTPM]":"129.3","Cell RNA - U-2197 [nTPM]":"56.2","Cell RNA - U-251 MG [nTPM]":"132.4","Cell RNA - U-266\/70 [nTPM]":"69.9","Cell RNA - U-266\/84 [nTPM]":"68.6","Cell RNA - U-698 [nTPM]":"247.4","Cell RNA - U-87 MG [nTPM]":"76.7","Cell RNA - U-937 [nTPM]":"130.9","Cell RNA - WM-115 [nTPM]":"73.8","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"20.6","Blood RNA - eosinophil [nTPM]":"7.4","Blood RNA - gdT-cell [nTPM]":"28.3","Blood RNA - intermediate monocyte [nTPM]":"16.9","Blood RNA - MAIT T-cell [nTPM]":"43.7","Blood RNA - memory B-cell [nTPM]":"26.5","Blood RNA - memory CD4 T-cell [nTPM]":"33.1","Blood RNA - memory CD8 T-cell [nTPM]":"34.1","Blood RNA - myeloid DC [nTPM]":"34.7","Blood RNA - naive B-cell [nTPM]":"22.3","Blood RNA - naive CD4 T-cell [nTPM]":"30.1","Blood RNA - naive CD8 T-cell [nTPM]":"28.4","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"30.2","Blood RNA - non-classical monocyte [nTPM]":"18.4","Blood RNA - plasmacytoid DC [nTPM]":"30.0","Blood RNA - T-reg [nTPM]":"48.7","Blood RNA - total PBMC [nTPM]":"31.2","Brain RNA - amygdala [nTPM]":"52.4","Brain RNA - basal ganglia [nTPM]":"55.9","Brain RNA - cerebellum [nTPM]":"62.5","Brain RNA - cerebral cortex [nTPM]":"66.9","Brain RNA - hippocampal formation [nTPM]":"57.9","Brain RNA - hypothalamus [nTPM]":"59.3","Brain RNA - medulla oblongata [nTPM]":"60.6","Brain RNA - midbrain [nTPM]":"51.0","Brain RNA - pons [nTPM]":"62.5","Brain RNA - spinal cord [nTPM]":"50.1","Brain RNA - thalamus [nTPM]":"58.7","Brain RNA - white matter [nTPM]":"61.0","Single Cell Type RNA - Adipocytes [nTPM]":"15.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"19.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"34.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"341.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"22.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"77.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.6","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"56.7","Single Cell Type RNA - Ductal cells [nTPM]":"50.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.0","Single Cell Type RNA - Endothelial cells [nTPM]":"23.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.5","Single Cell Type RNA - Erythroid cells [nTPM]":"39.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.8","Single Cell Type RNA - Fibroblasts [nTPM]":"21.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.4","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"37.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.2","Single Cell Type RNA - Hepatocytes [nTPM]":"176.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.1","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.5","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"17.0","Single Cell Type RNA - Langerhans cells [nTPM]":"15.1","Single Cell Type RNA - Late spermatids [nTPM]":"8.1","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"12.7","Single Cell Type RNA - Muller glia cells [nTPM]":"16.1","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.3","Single Cell Type RNA - Paneth cells [nTPM]":"13.3","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"39.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"63.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.0","Single Cell Type RNA - Spermatocytes [nTPM]":"11.9","Single Cell Type RNA - Spermatogonia [nTPM]":"15.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"68.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.7","Single Cell Type RNA - T-cells [nTPM]":"17.4","Single Cell Type RNA - Theca cells [nTPM]":"36.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.4","Single Cell Type RNA - Urothelial cells [nTPM]":"69.6"},{"Gene":"GPR143","Gene synonym":["OA1"],"Ensembl":"ENSG00000101850","Gene description":"G protein-coupled receptor 143","Uniprot":["P51810"],"Chromosome":"X","Position":"9725346-9786297","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Albinism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.2","choroid plexus":"14.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cytotrophoblasts":"40.6","Melanocytes":"126.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"melanoma":"84.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"3.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"3.1"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"SK-MEL-30":"159.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003648"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003648":"AB_2667028"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.73e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"10.6","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"11.8","Tissue RNA - cerebral cortex [nTPM]":"11.5","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"14.4","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"13.1","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"14.2","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"2.6","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"8.9","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"13.1","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"12.2","Cell RNA - A-431 [nTPM]":"1.9","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"4.6","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"1.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"2.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"3.4","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"24.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"12.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"11.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"22.2","Cell RNA - RT4 [nTPM]":"3.2","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"159.6","Cell RNA - SuSa [nTPM]":"10.8","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"4.6","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"3.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"10.6","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"11.8","Brain RNA - cerebral cortex [nTPM]":"11.5","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"13.1","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"14.2","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"13.1","Brain RNA - white matter [nTPM]":"12.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"126.3","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"GPR179","Gene synonym":["CSNB1E","GPR158L1"],"Ensembl":"ENSG00000277399","Gene description":"G protein-coupled receptor 179","Uniprot":[],"Chromosome":"17","Position":"38324571-38343956","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"retina":"13.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Bipolar cells":"25.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017885"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017885":"AB_2279357"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"13.9","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"1.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"1.8","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"25.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GPR88","Gene synonym":[],"Ensembl":"ENSG00000181656","Gene description":"G protein-coupled receptor 88","Uniprot":["Q9GZN0"],"Chromosome":"1","Position":"100538139-100542021","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"93.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"1.1","Excitatory neurons":"1.8","Hepatocytes":"2.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"12.0"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"basal ganglia":"93.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"HSkMC":"1.6","SCLC-21H":"2.0"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"10","RNA mouse brain regional specific nTPM":{"basal ganglia":"718.8"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"42","RNA pig brain regional specific nTPM":{"basal ganglia":"273.1"},"Antibody":["HPA007488"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007488":"AB_2667844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"93.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"7.2","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"8.9","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"10.1","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"7.5","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"93.9","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"10.1","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"7.5","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GPSM2","Gene synonym":["DFNB82","LGN","Pins"],"Ensembl":"ENSG00000121957","Gene description":"G protein signaling modulator 2","Uniprot":["P81274"],"Chromosome":"1","Position":"108875350-108934545","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","Transport"],"Molecular function":null,"Disease involvement":["Deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"46.9","tongue":"54.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"133.5","Oligodendrocyte precursor cells":"134.7","Oligodendrocytes":"127.4","Syncytiotrophoblasts":"89.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"3.2","T-reg":"1.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"3.2","T-cells":"1.8"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007327","HPA008408","CAB018962"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB018962":null,"HPA007327":"AB_1849941","HPA008408":"AB_1849939"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.86e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"27.3","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"39.5","Tissue RNA - bone marrow [nTPM]":"14.4","Tissue RNA - breast [nTPM]":"7.5","Tissue RNA - cerebellum [nTPM]":"33.8","Tissue RNA - cerebral cortex [nTPM]":"25.2","Tissue RNA - cervix [nTPM]":"12.6","Tissue RNA - choroid plexus [nTPM]":"10.8","Tissue RNA - colon [nTPM]":"15.3","Tissue RNA - duodenum [nTPM]":"9.1","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"34.1","Tissue RNA - fallopian tube [nTPM]":"4.2","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"23.3","Tissue RNA - hypothalamus [nTPM]":"29.5","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"9.0","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"33.9","Tissue RNA - midbrain [nTPM]":"36.3","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"3.6","Tissue RNA - parathyroid gland [nTPM]":"9.7","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"7.7","Tissue RNA - pons [nTPM]":"33.9","Tissue RNA - prostate [nTPM]":"5.9","Tissue RNA - rectum [nTPM]":"15.2","Tissue RNA - retina [nTPM]":"8.6","Tissue RNA - salivary gland [nTPM]":"10.1","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"10.7","Tissue RNA - skin 1 [nTPM]":"37.7","Tissue RNA - small intestine [nTPM]":"11.5","Tissue RNA - smooth muscle [nTPM]":"10.5","Tissue RNA - spinal cord [nTPM]":"32.1","Tissue RNA - spleen [nTPM]":"2.7","Tissue RNA - stomach 1 [nTPM]":"5.1","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"34.1","Tissue RNA - thymus [nTPM]":"18.4","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"54.4","Tissue RNA - tonsil [nTPM]":"13.2","Tissue RNA - urinary bladder [nTPM]":"6.0","Tissue RNA - vagina [nTPM]":"17.7","Tissue RNA - white matter [nTPM]":"46.9","Cell RNA - A-431 [nTPM]":"135.6","Cell RNA - A549 [nTPM]":"16.2","Cell RNA - AF22 [nTPM]":"36.8","Cell RNA - AN3-CA [nTPM]":"27.7","Cell RNA - ASC diff [nTPM]":"36.4","Cell RNA - ASC TERT1 [nTPM]":"20.2","Cell RNA - BEWO [nTPM]":"30.0","Cell RNA - BJ [nTPM]":"24.2","Cell RNA - BJ hTERT+ [nTPM]":"61.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"45.4","Cell RNA - CACO-2 [nTPM]":"16.0","Cell RNA - CAPAN-2 [nTPM]":"31.7","Cell RNA - Daudi [nTPM]":"30.5","Cell RNA - EFO-21 [nTPM]":"6.7","Cell RNA - fHDF\/TERT166 [nTPM]":"33.4","Cell RNA - GAMG [nTPM]":"21.0","Cell RNA - HaCaT [nTPM]":"28.3","Cell RNA - HAP1 [nTPM]":"25.3","Cell RNA - HBEC3-KT [nTPM]":"59.1","Cell RNA - HBF TERT88 [nTPM]":"39.6","Cell RNA - HDLM-2 [nTPM]":"30.7","Cell RNA - HEK 293 [nTPM]":"15.8","Cell RNA - HEL [nTPM]":"19.8","Cell RNA - HeLa [nTPM]":"34.7","Cell RNA - Hep G2 [nTPM]":"16.5","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"28.6","Cell RNA - HMC-1 [nTPM]":"18.5","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"113.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.4","Cell RNA - hTERT-HME1 [nTPM]":"129.8","Cell RNA - hTERT-RPE1 [nTPM]":"9.4","Cell RNA - HUVEC TERT2 [nTPM]":"26.9","Cell RNA - JURKAT [nTPM]":"19.5","Cell RNA - K-562 [nTPM]":"14.9","Cell RNA - Karpas-707 [nTPM]":"42.3","Cell RNA - LHCN-M2 [nTPM]":"58.4","Cell RNA - MCF7 [nTPM]":"37.8","Cell RNA - MOLT-4 [nTPM]":"26.1","Cell RNA - NB-4 [nTPM]":"12.2","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"52.1","Cell RNA - PC-3 [nTPM]":"29.4","Cell RNA - REH [nTPM]":"20.1","Cell RNA - RH-30 [nTPM]":"66.7","Cell RNA - RPMI-8226 [nTPM]":"6.6","Cell RNA - RPTEC TERT1 [nTPM]":"24.3","Cell RNA - RT4 [nTPM]":"18.6","Cell RNA - SCLC-21H [nTPM]":"30.4","Cell RNA - SH-SY5Y [nTPM]":"26.9","Cell RNA - SiHa [nTPM]":"37.0","Cell RNA - SK-BR-3 [nTPM]":"69.2","Cell RNA - SK-MEL-30 [nTPM]":"26.9","Cell RNA - SuSa [nTPM]":"10.3","Cell RNA - T-47d [nTPM]":"27.6","Cell RNA - THP-1 [nTPM]":"24.3","Cell RNA - TIME [nTPM]":"18.0","Cell RNA - U-138 MG [nTPM]":"21.7","Cell RNA - U-2 OS [nTPM]":"36.7","Cell RNA - U-2197 [nTPM]":"64.8","Cell RNA - U-251 MG [nTPM]":"48.5","Cell RNA - U-266\/70 [nTPM]":"18.4","Cell RNA - U-266\/84 [nTPM]":"20.9","Cell RNA - U-698 [nTPM]":"28.6","Cell RNA - U-87 MG [nTPM]":"34.3","Cell RNA - U-937 [nTPM]":"47.4","Cell RNA - WM-115 [nTPM]":"108.9","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"27.3","Brain RNA - basal ganglia [nTPM]":"39.5","Brain RNA - cerebellum [nTPM]":"33.8","Brain RNA - cerebral cortex [nTPM]":"25.2","Brain RNA - hippocampal formation [nTPM]":"23.3","Brain RNA - hypothalamus [nTPM]":"29.5","Brain RNA - medulla oblongata [nTPM]":"33.9","Brain RNA - midbrain [nTPM]":"36.3","Brain RNA - pons [nTPM]":"33.9","Brain RNA - spinal cord [nTPM]":"32.1","Brain RNA - thalamus [nTPM]":"34.1","Brain RNA - white matter [nTPM]":"46.9","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.3","Single Cell Type RNA - Astrocytes [nTPM]":"63.0","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"62.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Bipolar cells [nTPM]":"47.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"12.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"133.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.3","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"54.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.6","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"33.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"14.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.0","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.1","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.3","Single Cell Type RNA - Langerhans cells [nTPM]":"11.3","Single Cell Type RNA - Late spermatids [nTPM]":"21.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"4.9","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"5.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"134.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"127.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.8","Single Cell Type RNA - Paneth cells [nTPM]":"7.8","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"5.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.9","Single Cell Type RNA - Spermatocytes [nTPM]":"20.6","Single Cell Type RNA - Spermatogonia [nTPM]":"28.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"89.2","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"10.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.7","Single Cell Type RNA - Urothelial cells [nTPM]":"15.5"},{"Gene":"GRAP","Gene synonym":[],"Ensembl":"ENSG00000154016","Gene description":"GRB2 related adaptor protein","Uniprot":["Q13588"],"Chromosome":"17","Position":"19020656-19047011","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"37.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"11.2","B-cells":"21.2","Endothelial cells":"19.8","Hepatic stellate cells":"30.7","Microglial cells":"9.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"99.7","T-cells":"133.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"87.1","HUVEC TERT2":"38.9","JURKAT":"30.1","REH":"47.8","TIME":"70.4","U-698":"60.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046595","HPA066654"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA046595":"AB_10966385","HPA066654":"AB_2685699"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"5.9","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"6.9","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"1.8","Tissue RNA - fallopian tube [nTPM]":"4.6","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"4.9","Tissue RNA - liver [nTPM]":"6.0","Tissue RNA - lung [nTPM]":"7.1","Tissue RNA - lymph node [nTPM]":"36.9","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"3.7","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"15.7","Tissue RNA - smooth muscle [nTPM]":"3.3","Tissue RNA - spinal cord [nTPM]":"6.5","Tissue RNA - spleen [nTPM]":"37.5","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"6.3","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"31.9","Tissue RNA - thyroid gland [nTPM]":"5.5","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"30.7","Tissue RNA - urinary bladder [nTPM]":"3.6","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"6.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"4.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"87.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"38.9","Cell RNA - JURKAT [nTPM]":"30.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"19.9","Cell RNA - NB-4 [nTPM]":"1.9","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"47.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"9.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"6.8","Cell RNA - TIME [nTPM]":"70.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"9.8","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"60.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"21.5","Blood RNA - classical monocyte [nTPM]":"9.4","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"21.5","Blood RNA - intermediate monocyte [nTPM]":"4.8","Blood RNA - MAIT T-cell [nTPM]":"21.5","Blood RNA - memory B-cell [nTPM]":"99.7","Blood RNA - memory CD4 T-cell [nTPM]":"67.4","Blood RNA - memory CD8 T-cell [nTPM]":"28.4","Blood RNA - myeloid DC [nTPM]":"10.5","Blood RNA - naive B-cell [nTPM]":"82.7","Blood RNA - naive CD4 T-cell [nTPM]":"133.6","Blood RNA - naive CD8 T-cell [nTPM]":"66.5","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"21.4","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"7.9","Blood RNA - T-reg [nTPM]":"62.3","Blood RNA - total PBMC [nTPM]":"48.9","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"6.9","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"6.5","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"6.0","Single Cell Type RNA - Adipocytes [nTPM]":"11.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"21.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"19.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"2.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"6.9","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GRHL2","Gene synonym":["BOM","DFNA28","FLJ13782","TFCP2L3"],"Ensembl":"ENSG00000083307","Gene description":"Grainyhead like transcription factor 2","Uniprot":["Q6ISB3"],"Chromosome":"8","Position":"101492439-101669726","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Corneal dystrophy","Deafness","Disease variant","Dwarfism","Ectodermal dysplasia","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"28.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"32.1","Respiratory ciliated cells":"28.8","Squamous epithelial cells":"27.1","Suprabasal keratinocytes":"26.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"39.3","CACO-2":"28.0","HaCaT":"46.3","hTCEpi":"35.5","MCF7":"32.7","OE19":"37.9","RT4":"68.9","T-47d":"79.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004820","HPA062839"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA004820":"AB_1857928","HPA062839":"AB_2684878"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.43e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.27e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"12.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"6.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"8.0","Tissue RNA - duodenum [nTPM]":"4.0","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"16.1","Tissue RNA - esophagus [nTPM]":"20.4","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"5.6","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"11.1","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"23.2","Tissue RNA - rectum [nTPM]":"9.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"14.8","Tissue RNA - seminal vesicle [nTPM]":"7.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"28.6","Tissue RNA - small intestine [nTPM]":"4.3","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"9.8","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"7.7","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"39.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"19.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"28.0","Cell RNA - CAPAN-2 [nTPM]":"18.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"46.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"22.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"35.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"32.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"37.9","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"68.9","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"15.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"4.4","Cell RNA - T-47d [nTPM]":"79.7","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"20.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"9.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"8.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.8","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.3"},{"Gene":"GRID2","Gene synonym":["GluD2","GluR-delta-2"],"Ensembl":"ENSG00000152208","Gene description":"Glutamate ionotropic receptor delta type subunit 2","Uniprot":["O43424"],"Chromosome":"4","Position":"92303966-93810157","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"40.2","testis":"34.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"380.6","Excitatory neurons":"787.2","Inhibitory neurons":"982.0","Late spermatids":"674.2","Microglial cells":"382.2","Oligodendrocyte precursor cells":"2319.7","Oligodendrocytes":"453.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"1.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"40.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"U-2 OS":"7.7","U-266\/70":"3.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"cerebellum":"68.3"},"Antibody":["HPA056253","HPA058538"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056253":"AB_2683079","HPA058538":"AB_2683747"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"40.2","Tissue RNA - cerebral cortex [nTPM]":"4.0","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"10.7","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"5.3","Tissue RNA - ovary [nTPM]":"2.4","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"4.8","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"4.9","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"34.0","Tissue RNA - thalamus [nTPM]":"14.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"3.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"7.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.5","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"40.2","Brain RNA - cerebral cortex [nTPM]":"4.0","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"10.7","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"5.3","Brain RNA - pons [nTPM]":"4.8","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"14.2","Brain RNA - white matter [nTPM]":"3.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"86.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"108.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"380.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"787.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"982.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"674.2","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"382.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"115.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2319.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"453.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"6.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GRIN2A","Gene synonym":["GluN2A","NMDAR2A"],"Ensembl":"ENSG00000183454","Gene description":"Glutamate ionotropic receptor NMDA type subunit 2A","Uniprot":["Q12879"],"Chromosome":"16","Position":"9753404-10182928","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"31.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Excitatory neurons":"839.8","Inhibitory neurons":"904.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"0.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"31.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+ RasG12V":"1.1","fHDF\/TERT166":"4.4","hTERT-RPE1":"1.4","RPMI-8226":"1.8","U-138 MG":"4.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022725"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022725":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"4.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"31.7","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"20.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"4.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"4.6","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.7","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"31.7","Brain RNA - hippocampal formation [nTPM]":"20.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"10.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"17.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"839.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"904.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"15.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"65.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.4","Single Cell Type RNA - Spermatocytes [nTPM]":"8.2","Single Cell Type RNA - Spermatogonia [nTPM]":"10.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"GRIN2B","Gene synonym":["GluN2B","NMDAR2B"],"Ensembl":"ENSG00000273079","Gene description":"Glutamate ionotropic receptor NMDA type subunit 2B","Uniprot":["Q13224"],"Chromosome":"12","Position":"13437942-13982002","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"85","RNA tissue specific nTPM":{"brain":"36.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"625.2","Inhibitory neurons":"882.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"34","RNA brain regional specific nTPM":{"amygdala":"11.5","basal ganglia":"15.6","cerebral cortex":"36.1","hippocampal formation":"29.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"1.3","NTERA-2":"1.6","RPTEC TERT1":"1.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069762"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069762":"AB_2686192"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"11.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"15.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"36.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"29.4","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"11.5","Brain RNA - basal ganglia [nTPM]":"15.6","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"36.1","Brain RNA - hippocampal formation [nTPM]":"29.4","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"8.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"35.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"625.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"882.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"35.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"173.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"3.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GRIN2D","Gene synonym":["EB11","GluN2D","NMDAR2D","NR2D"],"Ensembl":"ENSG00000105464","Gene description":"Glutamate ionotropic receptor NMDA type subunit 2D","Uniprot":["O15399"],"Chromosome":"19","Position":"48393668-48444931","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"8.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Inhibitory neurons":"36.5","Oligodendrocyte precursor cells":"15.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"17.3","EFO-21":"11.5","HMC-1":"28.4","NB-4":"17.6","SK-BR-3":"15.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009006"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009006":"AB_2279191"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"4.8","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"1.5","Cell RNA - A549 [nTPM]":"17.3","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.2","Cell RNA - ASC TERT1 [nTPM]":"3.5","Cell RNA - BEWO [nTPM]":"9.8","Cell RNA - BJ [nTPM]":"2.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"10.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"11.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.1","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"2.3","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"5.4","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"2.2","Cell RNA - HHSteC [nTPM]":"1.8","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"28.4","Cell RNA - HSkMC [nTPM]":"1.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"9.9","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"17.6","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"8.6","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"15.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"6.6","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"5.8","Cell RNA - U-266\/84 [nTPM]":"3.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"4.8","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GRK1","Gene synonym":["GPRK1","RHOK","RK"],"Ensembl":"ENSG00000185974","Gene description":"G protein-coupled receptor kinase 1","Uniprot":["Q15835"],"Chromosome":"13","Position":"113667219-113737736","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"50","RNA tissue specific nTPM":{"retina":"42.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"56.3","Rod photoreceptor cells":"84.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035200","HPA059376"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035200":"AB_2674515","HPA059376":"AB_2683996"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"42.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"84.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GRM1","Gene synonym":["GPRC1A","mGlu1","MGLUR1","PPP1R85"],"Ensembl":"ENSG00000152822","Gene description":"Glutamate metabotropic receptor 1","Uniprot":["Q13255"],"Chromosome":"6","Position":"146027646-146437601","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"27.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"215.5","Inhibitory neurons":"138.8","Rod photoreceptor cells":"124.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"27.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015701"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA015701":"AB_1853917"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"3.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"27.6","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.3","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"27.6","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"13.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"215.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"138.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"124.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GRM6","Gene synonym":["CSNB1B","GPRC1F","mGlu6","MGLUR6"],"Ensembl":"ENSG00000113262","Gene description":"Glutamate metabotropic receptor 6","Uniprot":["O15303"],"Chromosome":"5","Position":"178977587-178996206","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"57","RNA tissue specific nTPM":{"retina":"42.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"31","RNA single cell type specific nTPM":{"Bipolar cells":"440.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014511"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014511":"AB_2669025"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"42.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"440.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"4.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GRN","Gene synonym":["CLN11","PCDGF","PGRN"],"Ensembl":"ENSG00000030582","Gene description":"Granulin precursor","Uniprot":["P28799"],"Chromosome":"17","Position":"44345246-44353106","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"1420.7","Kupffer cells":"892.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"2057.5","intermediate monocyte":"1122.4","myeloid DC":"1534.2","neutrophil":"851.2","non-classical monocyte":"548.1","plasmacytoid DC":"1331.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"1534.2","granulocytes":"851.2","monocytes":"2057.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008763","CAB019394","HPA028747"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endosomes","Lysosomes"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":138000000,"Blood concentration - Conc. blood MS [pg\/L]":"110000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Lysosomes"],"Subcellular additional location":["Endosomes"],"Antibody RRID":{"CAB019394":null,"HPA008763":"AB_1850339","HPA028747":"AB_10603767"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.78e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"158.9","Tissue RNA - adrenal gland [nTPM]":"123.2","Tissue RNA - amygdala [nTPM]":"61.5","Tissue RNA - appendix [nTPM]":"160.4","Tissue RNA - basal ganglia [nTPM]":"67.2","Tissue RNA - bone marrow [nTPM]":"478.5","Tissue RNA - breast [nTPM]":"120.7","Tissue RNA - cerebellum [nTPM]":"67.7","Tissue RNA - cerebral cortex [nTPM]":"97.3","Tissue RNA - cervix [nTPM]":"156.7","Tissue RNA - choroid plexus [nTPM]":"73.9","Tissue RNA - colon [nTPM]":"189.8","Tissue RNA - duodenum [nTPM]":"130.9","Tissue RNA - endometrium 1 [nTPM]":"108.3","Tissue RNA - epididymis [nTPM]":"134.0","Tissue RNA - esophagus [nTPM]":"534.0","Tissue RNA - fallopian tube [nTPM]":"87.1","Tissue RNA - gallbladder [nTPM]":"157.3","Tissue RNA - heart muscle [nTPM]":"153.0","Tissue RNA - hippocampal formation [nTPM]":"61.0","Tissue RNA - hypothalamus [nTPM]":"69.7","Tissue RNA - kidney [nTPM]":"167.4","Tissue RNA - liver [nTPM]":"118.9","Tissue RNA - lung [nTPM]":"309.5","Tissue RNA - lymph node [nTPM]":"183.2","Tissue RNA - medulla oblongata [nTPM]":"81.0","Tissue RNA - midbrain [nTPM]":"71.5","Tissue RNA - ovary [nTPM]":"73.8","Tissue RNA - pancreas [nTPM]":"108.9","Tissue RNA - parathyroid gland [nTPM]":"87.8","Tissue RNA - pituitary gland [nTPM]":"84.4","Tissue RNA - placenta [nTPM]":"183.2","Tissue RNA - pons [nTPM]":"87.6","Tissue RNA - prostate [nTPM]":"111.7","Tissue RNA - rectum [nTPM]":"110.3","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"262.9","Tissue RNA - seminal vesicle [nTPM]":"100.6","Tissue RNA - skeletal muscle [nTPM]":"60.6","Tissue RNA - skin 1 [nTPM]":"189.7","Tissue RNA - small intestine [nTPM]":"179.0","Tissue RNA - smooth muscle [nTPM]":"91.9","Tissue RNA - spinal cord [nTPM]":"71.8","Tissue RNA - spleen [nTPM]":"349.8","Tissue RNA - stomach 1 [nTPM]":"127.9","Tissue RNA - testis [nTPM]":"59.4","Tissue RNA - thalamus [nTPM]":"94.3","Tissue RNA - thymus [nTPM]":"67.8","Tissue RNA - thyroid gland [nTPM]":"127.7","Tissue RNA - tongue [nTPM]":"45.9","Tissue RNA - tonsil [nTPM]":"107.8","Tissue RNA - urinary bladder [nTPM]":"150.0","Tissue RNA - vagina [nTPM]":"198.3","Tissue RNA - white matter [nTPM]":"97.3","Cell RNA - A-431 [nTPM]":"119.3","Cell RNA - A549 [nTPM]":"197.5","Cell RNA - AF22 [nTPM]":"52.7","Cell RNA - AN3-CA [nTPM]":"159.5","Cell RNA - ASC diff [nTPM]":"443.2","Cell RNA - ASC TERT1 [nTPM]":"231.8","Cell RNA - BEWO [nTPM]":"181.2","Cell RNA - BJ [nTPM]":"147.3","Cell RNA - BJ hTERT+ [nTPM]":"447.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"231.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"309.8","Cell RNA - CACO-2 [nTPM]":"86.3","Cell RNA - CAPAN-2 [nTPM]":"294.0","Cell RNA - Daudi [nTPM]":"364.0","Cell RNA - EFO-21 [nTPM]":"299.4","Cell RNA - fHDF\/TERT166 [nTPM]":"217.6","Cell RNA - GAMG [nTPM]":"312.9","Cell RNA - HaCaT [nTPM]":"185.3","Cell RNA - HAP1 [nTPM]":"68.6","Cell RNA - HBEC3-KT [nTPM]":"334.5","Cell RNA - HBF TERT88 [nTPM]":"75.8","Cell RNA - HDLM-2 [nTPM]":"55.8","Cell RNA - HEK 293 [nTPM]":"186.8","Cell RNA - HEL [nTPM]":"38.4","Cell RNA - HeLa [nTPM]":"93.8","Cell RNA - Hep G2 [nTPM]":"175.2","Cell RNA - HHSteC [nTPM]":"245.5","Cell RNA - HL-60 [nTPM]":"61.6","Cell RNA - HMC-1 [nTPM]":"493.6","Cell RNA - HSkMC [nTPM]":"332.4","Cell RNA - hTCEpi [nTPM]":"450.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"188.1","Cell RNA - hTERT-HME1 [nTPM]":"106.0","Cell RNA - hTERT-RPE1 [nTPM]":"391.2","Cell RNA - HUVEC TERT2 [nTPM]":"269.8","Cell RNA - JURKAT [nTPM]":"64.3","Cell RNA - K-562 [nTPM]":"75.1","Cell RNA - Karpas-707 [nTPM]":"51.3","Cell RNA - LHCN-M2 [nTPM]":"148.8","Cell RNA - MCF7 [nTPM]":"183.1","Cell RNA - MOLT-4 [nTPM]":"32.8","Cell RNA - NB-4 [nTPM]":"172.8","Cell RNA - NTERA-2 [nTPM]":"44.3","Cell RNA - OE19 [nTPM]":"110.5","Cell RNA - PC-3 [nTPM]":"334.0","Cell RNA - REH [nTPM]":"97.7","Cell RNA - RH-30 [nTPM]":"180.8","Cell RNA - RPMI-8226 [nTPM]":"433.0","Cell RNA - RPTEC TERT1 [nTPM]":"248.2","Cell RNA - RT4 [nTPM]":"145.9","Cell RNA - SCLC-21H [nTPM]":"54.7","Cell RNA - SH-SY5Y [nTPM]":"74.7","Cell RNA - SiHa [nTPM]":"201.0","Cell RNA - SK-BR-3 [nTPM]":"92.7","Cell RNA - SK-MEL-30 [nTPM]":"360.9","Cell RNA - SuSa [nTPM]":"138.0","Cell RNA - T-47d [nTPM]":"209.4","Cell RNA - THP-1 [nTPM]":"229.0","Cell RNA - TIME [nTPM]":"340.7","Cell RNA - U-138 MG [nTPM]":"437.6","Cell RNA - U-2 OS [nTPM]":"104.6","Cell RNA - U-2197 [nTPM]":"300.5","Cell RNA - U-251 MG [nTPM]":"97.8","Cell RNA - U-266\/70 [nTPM]":"116.3","Cell RNA - U-266\/84 [nTPM]":"313.9","Cell RNA - U-698 [nTPM]":"122.3","Cell RNA - U-87 MG [nTPM]":"268.1","Cell RNA - U-937 [nTPM]":"149.6","Cell RNA - WM-115 [nTPM]":"124.2","Blood RNA - basophil [nTPM]":"215.1","Blood RNA - classical monocyte [nTPM]":"2057.5","Blood RNA - eosinophil [nTPM]":"176.5","Blood RNA - gdT-cell [nTPM]":"35.1","Blood RNA - intermediate monocyte [nTPM]":"1122.4","Blood RNA - MAIT T-cell [nTPM]":"27.8","Blood RNA - memory B-cell [nTPM]":"174.0","Blood RNA - memory CD4 T-cell [nTPM]":"37.1","Blood RNA - memory CD8 T-cell [nTPM]":"31.1","Blood RNA - myeloid DC [nTPM]":"1534.2","Blood RNA - naive B-cell [nTPM]":"112.2","Blood RNA - naive CD4 T-cell [nTPM]":"27.8","Blood RNA - naive CD8 T-cell [nTPM]":"26.5","Blood RNA - neutrophil [nTPM]":"851.2","Blood RNA - NK-cell [nTPM]":"30.6","Blood RNA - non-classical monocyte [nTPM]":"548.1","Blood RNA - plasmacytoid DC [nTPM]":"1331.9","Blood RNA - T-reg [nTPM]":"55.4","Blood RNA - total PBMC [nTPM]":"1613.4","Brain RNA - amygdala [nTPM]":"61.5","Brain RNA - basal ganglia [nTPM]":"67.2","Brain RNA - cerebellum [nTPM]":"67.7","Brain RNA - cerebral cortex [nTPM]":"97.3","Brain RNA - hippocampal formation [nTPM]":"61.0","Brain RNA - hypothalamus [nTPM]":"69.7","Brain RNA - medulla oblongata [nTPM]":"81.0","Brain RNA - midbrain [nTPM]":"71.5","Brain RNA - pons [nTPM]":"87.6","Brain RNA - spinal cord [nTPM]":"71.8","Brain RNA - thalamus [nTPM]":"94.3","Brain RNA - white matter [nTPM]":"97.3","Single Cell Type RNA - Adipocytes [nTPM]":"113.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"83.3","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"82.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"112.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"151.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"574.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"97.9","Single Cell Type RNA - Bipolar cells [nTPM]":"23.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"85.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"69.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"90.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"133.0","Single Cell Type RNA - Club cells [nTPM]":"332.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"218.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"429.1","Single Cell Type RNA - dendritic cells [nTPM]":"195.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"494.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"447.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"103.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"83.8","Single Cell Type RNA - Endothelial cells [nTPM]":"170.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"124.3","Single Cell Type RNA - Erythroid cells [nTPM]":"38.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"307.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"324.1","Single Cell Type RNA - Fibroblasts [nTPM]":"149.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"83.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"372.5","Single Cell Type RNA - granulocytes [nTPM]":"75.5","Single Cell Type RNA - Granulosa cells [nTPM]":"90.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"207.8","Single Cell Type RNA - Hepatocytes [nTPM]":"84.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1420.7","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"214.6","Single Cell Type RNA - Ionocytes [nTPM]":"146.5","Single Cell Type RNA - Kupffer cells [nTPM]":"892.0","Single Cell Type RNA - Langerhans cells [nTPM]":"360.8","Single Cell Type RNA - Late spermatids [nTPM]":"6.8","Single Cell Type RNA - Leydig cells [nTPM]":"60.9","Single Cell Type RNA - Macrophages [nTPM]":"699.2","Single Cell Type RNA - Melanocytes [nTPM]":"208.1","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"501.6","Single Cell Type RNA - Muller glia cells [nTPM]":"58.9","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"285.3","Single Cell Type RNA - Paneth cells [nTPM]":"581.7","Single Cell Type RNA - Peritubular cells [nTPM]":"57.2","Single Cell Type RNA - Plasma cells [nTPM]":"65.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"70.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"312.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"120.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"70.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.8","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"83.3","Single Cell Type RNA - Spermatocytes [nTPM]":"25.1","Single Cell Type RNA - Spermatogonia [nTPM]":"72.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"255.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"96.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"640.0","Single Cell Type RNA - T-cells [nTPM]":"30.8","Single Cell Type RNA - Theca cells [nTPM]":"89.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"274.5","Single Cell Type RNA - Urothelial cells [nTPM]":"175.6"},{"Gene":"GRXCR1","Gene synonym":["DFNB25","PPP1R88"],"Ensembl":"ENSG00000215203","Gene description":"Glutaredoxin and cysteine rich domain containing 1","Uniprot":["A8MXD5"],"Chromosome":"4","Position":"42892713-43030658","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"seminal vesicle":"2.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"3.2","Spermatocytes":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040824"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040824":"AB_10794863"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GRXCR2","Gene synonym":["DFNB101"],"Ensembl":"ENSG00000204928","Gene description":"Glutaredoxin and cysteine rich domain containing 2","Uniprot":["A6NFK2"],"Chromosome":"5","Position":"145858521-145937126","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"15.1","Late spermatids":"16.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"cerebral cortex":"1.2","hippocampal formation":"4.1"},"Antibody":["HPA059421"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059421":"AB_2684010"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"15.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"16.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GSDME","Gene synonym":["DFNA5","ICERE-1"],"Ensembl":"ENSG00000105928","Gene description":"Gasdermin E","Uniprot":["O60443"],"Chromosome":"7","Position":"24698355-24757940","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Necrosis"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"168.1","Distal tubular cells":"41.1","Extravillous trophoblasts":"26.5","Hofbauer cells":"39.9","Syncytiotrophoblasts":"104.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"9.0","myeloid DC":"5.9","naive B-cell":"8.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011326","CAB019306"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB019306":null,"HPA011326":"AB_1847629"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.5","Tissue RNA - adrenal gland [nTPM]":"7.8","Tissue RNA - amygdala [nTPM]":"16.4","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"16.7","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"13.3","Tissue RNA - cerebral cortex [nTPM]":"18.0","Tissue RNA - cervix [nTPM]":"17.3","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"24.8","Tissue RNA - epididymis [nTPM]":"15.3","Tissue RNA - esophagus [nTPM]":"3.6","Tissue RNA - fallopian tube [nTPM]":"14.3","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"9.7","Tissue RNA - hippocampal formation [nTPM]":"18.1","Tissue RNA - hypothalamus [nTPM]":"15.0","Tissue RNA - kidney [nTPM]":"13.3","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"19.4","Tissue RNA - midbrain [nTPM]":"18.7","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"7.3","Tissue RNA - pituitary gland [nTPM]":"7.0","Tissue RNA - placenta [nTPM]":"35.0","Tissue RNA - pons [nTPM]":"16.1","Tissue RNA - prostate [nTPM]":"7.5","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"21.1","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"26.8","Tissue RNA - smooth muscle [nTPM]":"15.1","Tissue RNA - spinal cord [nTPM]":"16.5","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"12.9","Tissue RNA - thalamus [nTPM]":"14.1","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"14.5","Tissue RNA - tongue [nTPM]":"5.2","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"15.0","Tissue RNA - vagina [nTPM]":"10.1","Tissue RNA - white matter [nTPM]":"26.6","Cell RNA - A-431 [nTPM]":"31.4","Cell RNA - A549 [nTPM]":"21.7","Cell RNA - AF22 [nTPM]":"9.6","Cell RNA - AN3-CA [nTPM]":"41.2","Cell RNA - ASC diff [nTPM]":"51.4","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"16.4","Cell RNA - BJ [nTPM]":"24.1","Cell RNA - BJ hTERT+ [nTPM]":"63.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.3","Cell RNA - CACO-2 [nTPM]":"22.9","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"20.6","Cell RNA - fHDF\/TERT166 [nTPM]":"66.4","Cell RNA - GAMG [nTPM]":"81.7","Cell RNA - HaCaT [nTPM]":"20.5","Cell RNA - HAP1 [nTPM]":"5.8","Cell RNA - HBEC3-KT [nTPM]":"105.4","Cell RNA - HBF TERT88 [nTPM]":"42.8","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"39.3","Cell RNA - Hep G2 [nTPM]":"48.0","Cell RNA - HHSteC [nTPM]":"43.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"1.5","Cell RNA - HSkMC [nTPM]":"31.3","Cell RNA - hTCEpi [nTPM]":"75.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.5","Cell RNA - hTERT-HME1 [nTPM]":"103.1","Cell RNA - hTERT-RPE1 [nTPM]":"73.0","Cell RNA - HUVEC TERT2 [nTPM]":"42.3","Cell RNA - JURKAT [nTPM]":"13.8","Cell RNA - K-562 [nTPM]":"3.0","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"55.3","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"10.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"15.7","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"33.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"74.5","Cell RNA - RT4 [nTPM]":"21.9","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"60.0","Cell RNA - SiHa [nTPM]":"36.5","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"42.3","Cell RNA - SuSa [nTPM]":"24.3","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"2.8","Cell RNA - TIME [nTPM]":"27.9","Cell RNA - U-138 MG [nTPM]":"23.1","Cell RNA - U-2 OS [nTPM]":"39.7","Cell RNA - U-2197 [nTPM]":"31.6","Cell RNA - U-251 MG [nTPM]":"29.2","Cell RNA - U-266\/70 [nTPM]":"2.4","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"15.5","Cell RNA - U-87 MG [nTPM]":"69.8","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"5.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"9.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"5.9","Blood RNA - naive B-cell [nTPM]":"8.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"16.4","Brain RNA - basal ganglia [nTPM]":"16.7","Brain RNA - cerebellum [nTPM]":"13.3","Brain RNA - cerebral cortex [nTPM]":"18.0","Brain RNA - hippocampal formation [nTPM]":"18.1","Brain RNA - hypothalamus [nTPM]":"15.0","Brain RNA - medulla oblongata [nTPM]":"19.4","Brain RNA - midbrain [nTPM]":"18.7","Brain RNA - pons [nTPM]":"16.1","Brain RNA - spinal cord [nTPM]":"16.5","Brain RNA - thalamus [nTPM]":"14.1","Brain RNA - white matter [nTPM]":"26.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"168.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.9","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.5","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"6.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"8.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"104.7","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GSN","Gene synonym":["DKFZp313L0718"],"Ensembl":"ENSG00000148180","Gene description":"Gelsolin","Uniprot":["P06396"],"Chromosome":"9","Position":"121207794-121332843","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Actin capping","Actin-binding"],"Disease involvement":["Amyloidosis","Cancer-related genes","Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"2486.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"1649.5","Fibroblasts":"4145.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1135.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1313.9","HaCaT":"533.6"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"white matter":"869.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010823","CAB016728","CAB036009","HPA054026"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Actin filaments"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":112000000000,"Blood concentration - Conc. blood MS [pg\/L]":"240000000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"CAB010823":null,"CAB016728":null,"CAB036009":null,"HPA054026":"AB_2682347"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.79e-5"},"Tissue RNA - adipose tissue [nTPM]":"1892.9","Tissue RNA - adrenal gland [nTPM]":"162.5","Tissue RNA - amygdala [nTPM]":"169.7","Tissue RNA - appendix [nTPM]":"109.7","Tissue RNA - basal ganglia [nTPM]":"317.4","Tissue RNA - bone marrow [nTPM]":"175.0","Tissue RNA - breast [nTPM]":"1244.6","Tissue RNA - cerebellum [nTPM]":"291.2","Tissue RNA - cerebral cortex [nTPM]":"213.0","Tissue RNA - cervix [nTPM]":"577.4","Tissue RNA - choroid plexus [nTPM]":"155.6","Tissue RNA - colon [nTPM]":"867.4","Tissue RNA - duodenum [nTPM]":"152.0","Tissue RNA - endometrium 1 [nTPM]":"767.7","Tissue RNA - epididymis [nTPM]":"108.2","Tissue RNA - esophagus [nTPM]":"435.1","Tissue RNA - fallopian tube [nTPM]":"663.2","Tissue RNA - gallbladder [nTPM]":"226.1","Tissue RNA - heart muscle [nTPM]":"2486.9","Tissue RNA - hippocampal formation [nTPM]":"163.4","Tissue RNA - hypothalamus [nTPM]":"219.8","Tissue RNA - kidney [nTPM]":"153.1","Tissue RNA - liver [nTPM]":"40.6","Tissue RNA - lung [nTPM]":"308.7","Tissue RNA - lymph node [nTPM]":"93.2","Tissue RNA - medulla oblongata [nTPM]":"380.9","Tissue RNA - midbrain [nTPM]":"284.6","Tissue RNA - ovary [nTPM]":"303.8","Tissue RNA - pancreas [nTPM]":"140.7","Tissue RNA - parathyroid gland [nTPM]":"70.9","Tissue RNA - pituitary gland [nTPM]":"260.6","Tissue RNA - placenta [nTPM]":"79.0","Tissue RNA - pons [nTPM]":"354.7","Tissue RNA - prostate [nTPM]":"344.0","Tissue RNA - rectum [nTPM]":"204.6","Tissue RNA - retina [nTPM]":"57.8","Tissue RNA - salivary gland [nTPM]":"508.7","Tissue RNA - seminal vesicle [nTPM]":"400.9","Tissue RNA - skeletal muscle [nTPM]":"420.4","Tissue RNA - skin 1 [nTPM]":"612.9","Tissue RNA - small intestine [nTPM]":"384.1","Tissue RNA - smooth muscle [nTPM]":"350.0","Tissue RNA - spinal cord [nTPM]":"270.6","Tissue RNA - spleen [nTPM]":"136.5","Tissue RNA - stomach 1 [nTPM]":"469.7","Tissue RNA - testis [nTPM]":"78.1","Tissue RNA - thalamus [nTPM]":"279.0","Tissue RNA - thymus [nTPM]":"99.7","Tissue RNA - thyroid gland [nTPM]":"702.6","Tissue RNA - tongue [nTPM]":"687.8","Tissue RNA - tonsil [nTPM]":"87.3","Tissue RNA - urinary bladder [nTPM]":"897.2","Tissue RNA - vagina [nTPM]":"655.5","Tissue RNA - white matter [nTPM]":"376.1","Cell RNA - A-431 [nTPM]":"38.4","Cell RNA - A549 [nTPM]":"60.9","Cell RNA - AF22 [nTPM]":"39.0","Cell RNA - AN3-CA [nTPM]":"129.8","Cell RNA - ASC diff [nTPM]":"1313.9","Cell RNA - ASC TERT1 [nTPM]":"351.8","Cell RNA - BEWO [nTPM]":"26.4","Cell RNA - BJ [nTPM]":"130.9","Cell RNA - BJ hTERT+ [nTPM]":"264.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.5","Cell RNA - CACO-2 [nTPM]":"64.2","Cell RNA - CAPAN-2 [nTPM]":"130.1","Cell RNA - Daudi [nTPM]":"3.0","Cell RNA - EFO-21 [nTPM]":"36.6","Cell RNA - fHDF\/TERT166 [nTPM]":"182.8","Cell RNA - GAMG [nTPM]":"48.5","Cell RNA - HaCaT [nTPM]":"533.6","Cell RNA - HAP1 [nTPM]":"3.2","Cell RNA - HBEC3-KT [nTPM]":"84.3","Cell RNA - HBF TERT88 [nTPM]":"16.9","Cell RNA - HDLM-2 [nTPM]":"6.5","Cell RNA - HEK 293 [nTPM]":"7.6","Cell RNA - HEL [nTPM]":"31.2","Cell RNA - HeLa [nTPM]":"57.1","Cell RNA - Hep G2 [nTPM]":"167.5","Cell RNA - HHSteC [nTPM]":"32.0","Cell RNA - HL-60 [nTPM]":"7.0","Cell RNA - HMC-1 [nTPM]":"146.0","Cell RNA - HSkMC [nTPM]":"140.0","Cell RNA - hTCEpi [nTPM]":"84.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"51.7","Cell RNA - hTERT-HME1 [nTPM]":"34.4","Cell RNA - hTERT-RPE1 [nTPM]":"83.1","Cell RNA - HUVEC TERT2 [nTPM]":"120.4","Cell RNA - JURKAT [nTPM]":"6.1","Cell RNA - K-562 [nTPM]":"10.4","Cell RNA - Karpas-707 [nTPM]":"5.3","Cell RNA - LHCN-M2 [nTPM]":"137.0","Cell RNA - MCF7 [nTPM]":"81.1","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"304.4","Cell RNA - NTERA-2 [nTPM]":"12.7","Cell RNA - OE19 [nTPM]":"76.2","Cell RNA - PC-3 [nTPM]":"45.1","Cell RNA - REH [nTPM]":"8.4","Cell RNA - RH-30 [nTPM]":"13.1","Cell RNA - RPMI-8226 [nTPM]":"4.3","Cell RNA - RPTEC TERT1 [nTPM]":"156.4","Cell RNA - RT4 [nTPM]":"63.4","Cell RNA - SCLC-21H [nTPM]":"7.7","Cell RNA - SH-SY5Y [nTPM]":"10.4","Cell RNA - SiHa [nTPM]":"60.9","Cell RNA - SK-BR-3 [nTPM]":"62.5","Cell RNA - SK-MEL-30 [nTPM]":"197.2","Cell RNA - SuSa [nTPM]":"84.6","Cell RNA - T-47d [nTPM]":"245.3","Cell RNA - THP-1 [nTPM]":"158.8","Cell RNA - TIME [nTPM]":"217.4","Cell RNA - U-138 MG [nTPM]":"100.0","Cell RNA - U-2 OS [nTPM]":"33.2","Cell RNA - U-2197 [nTPM]":"10.4","Cell RNA - U-251 MG [nTPM]":"12.8","Cell RNA - U-266\/70 [nTPM]":"1.8","Cell RNA - U-266\/84 [nTPM]":"2.0","Cell RNA - U-698 [nTPM]":"3.2","Cell RNA - U-87 MG [nTPM]":"105.3","Cell RNA - U-937 [nTPM]":"18.2","Cell RNA - WM-115 [nTPM]":"278.1","Blood RNA - basophil [nTPM]":"302.9","Blood RNA - classical monocyte [nTPM]":"122.0","Blood RNA - eosinophil [nTPM]":"1135.9","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"84.9","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"17.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"345.3","Blood RNA - naive B-cell [nTPM]":"6.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"307.1","Blood RNA - NK-cell [nTPM]":"217.8","Blood RNA - non-classical monocyte [nTPM]":"23.7","Blood RNA - plasmacytoid DC [nTPM]":"243.2","Blood RNA - T-reg [nTPM]":"4.2","Blood RNA - total PBMC [nTPM]":"105.4","Brain RNA - amygdala [nTPM]":"169.7","Brain RNA - basal ganglia [nTPM]":"317.4","Brain RNA - cerebellum [nTPM]":"291.2","Brain RNA - cerebral cortex [nTPM]":"213.0","Brain RNA - hippocampal formation [nTPM]":"163.4","Brain RNA - hypothalamus [nTPM]":"219.8","Brain RNA - medulla oblongata [nTPM]":"380.9","Brain RNA - midbrain [nTPM]":"284.6","Brain RNA - pons [nTPM]":"354.7","Brain RNA - spinal cord [nTPM]":"270.6","Brain RNA - thalamus [nTPM]":"279.0","Brain RNA - white matter [nTPM]":"376.1","Single Cell Type RNA - Adipocytes [nTPM]":"1649.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"147.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"55.7","Single Cell Type RNA - Astrocytes [nTPM]":"82.3","Single Cell Type RNA - B-cells [nTPM]":"22.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"341.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"278.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"252.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"103.0","Single Cell Type RNA - Bipolar cells [nTPM]":"7.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"120.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"212.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"272.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"85.8","Single Cell Type RNA - Club cells [nTPM]":"354.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"121.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"77.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.8","Single Cell Type RNA - dendritic cells [nTPM]":"74.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"557.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"105.7","Single Cell Type RNA - Ductal cells [nTPM]":"258.5","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"141.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"163.1","Single Cell Type RNA - Endothelial cells [nTPM]":"724.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"63.1","Single Cell Type RNA - Erythroid cells [nTPM]":"17.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"202.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"94.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4145.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"322.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"220.6","Single Cell Type RNA - granulocytes [nTPM]":"104.0","Single Cell Type RNA - Granulosa cells [nTPM]":"31.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"273.5","Single Cell Type RNA - Hepatocytes [nTPM]":"16.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"492.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"762.9","Single Cell Type RNA - Ionocytes [nTPM]":"512.7","Single Cell Type RNA - Kupffer cells [nTPM]":"139.0","Single Cell Type RNA - Langerhans cells [nTPM]":"798.7","Single Cell Type RNA - Late spermatids [nTPM]":"20.2","Single Cell Type RNA - Leydig cells [nTPM]":"588.7","Single Cell Type RNA - Macrophages [nTPM]":"273.7","Single Cell Type RNA - Melanocytes [nTPM]":"537.2","Single Cell Type RNA - Microglial cells [nTPM]":"155.5","Single Cell Type RNA - monocytes [nTPM]":"487.5","Single Cell Type RNA - Muller glia cells [nTPM]":"220.6","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"443.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"315.8","Single Cell Type RNA - Paneth cells [nTPM]":"590.5","Single Cell Type RNA - Peritubular cells [nTPM]":"671.8","Single Cell Type RNA - Plasma cells [nTPM]":"24.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"91.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"77.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"583.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"86.5","Single Cell Type RNA - Sertoli cells [nTPM]":"611.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"362.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"740.4","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"13.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"175.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"299.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"84.0","Single Cell Type RNA - T-cells [nTPM]":"58.7","Single Cell Type RNA - Theca cells [nTPM]":"34.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.2","Single Cell Type RNA - Urothelial cells [nTPM]":"144.7"},{"Gene":"GTPBP2","Gene synonym":[],"Ensembl":"ENSG00000172432","Gene description":"GTP binding protein 2","Uniprot":["Q9BX10"],"Chromosome":"6","Position":"43605316-43629264","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"47.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"5.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"5.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"181.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031418","HPA031419"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031418":"AB_2673872","HPA031419":"AB_10600709"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.44e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Tissue RNA - adipose tissue [nTPM]":"38.5","Tissue RNA - adrenal gland [nTPM]":"29.8","Tissue RNA - amygdala [nTPM]":"14.5","Tissue RNA - appendix [nTPM]":"15.3","Tissue RNA - basal ganglia [nTPM]":"15.3","Tissue RNA - bone marrow [nTPM]":"28.7","Tissue RNA - breast [nTPM]":"37.4","Tissue RNA - cerebellum [nTPM]":"16.5","Tissue RNA - cerebral cortex [nTPM]":"17.9","Tissue RNA - cervix [nTPM]":"39.5","Tissue RNA - choroid plexus [nTPM]":"16.0","Tissue RNA - colon [nTPM]":"34.0","Tissue RNA - duodenum [nTPM]":"19.9","Tissue RNA - endometrium 1 [nTPM]":"26.8","Tissue RNA - epididymis [nTPM]":"15.5","Tissue RNA - esophagus [nTPM]":"61.3","Tissue RNA - fallopian tube [nTPM]":"25.1","Tissue RNA - gallbladder [nTPM]":"12.5","Tissue RNA - heart muscle [nTPM]":"35.4","Tissue RNA - hippocampal formation [nTPM]":"14.4","Tissue RNA - hypothalamus [nTPM]":"15.0","Tissue RNA - kidney [nTPM]":"36.1","Tissue RNA - liver [nTPM]":"33.3","Tissue RNA - lung [nTPM]":"46.7","Tissue RNA - lymph node [nTPM]":"16.9","Tissue RNA - medulla oblongata [nTPM]":"17.5","Tissue RNA - midbrain [nTPM]":"16.7","Tissue RNA - ovary [nTPM]":"29.0","Tissue RNA - pancreas [nTPM]":"40.0","Tissue RNA - parathyroid gland [nTPM]":"24.1","Tissue RNA - pituitary gland [nTPM]":"40.0","Tissue RNA - placenta [nTPM]":"18.0","Tissue RNA - pons [nTPM]":"15.6","Tissue RNA - prostate [nTPM]":"31.5","Tissue RNA - rectum [nTPM]":"17.0","Tissue RNA - retina [nTPM]":"18.9","Tissue RNA - salivary gland [nTPM]":"42.6","Tissue RNA - seminal vesicle [nTPM]":"11.6","Tissue RNA - skeletal muscle [nTPM]":"31.6","Tissue RNA - skin 1 [nTPM]":"26.5","Tissue RNA - small intestine [nTPM]":"34.7","Tissue RNA - smooth muscle [nTPM]":"15.4","Tissue RNA - spinal cord [nTPM]":"14.3","Tissue RNA - spleen [nTPM]":"44.5","Tissue RNA - stomach 1 [nTPM]":"35.9","Tissue RNA - testis [nTPM]":"27.2","Tissue RNA - thalamus [nTPM]":"17.0","Tissue RNA - thymus [nTPM]":"16.8","Tissue RNA - thyroid gland [nTPM]":"44.2","Tissue RNA - tongue [nTPM]":"10.4","Tissue RNA - tonsil [nTPM]":"17.0","Tissue RNA - urinary bladder [nTPM]":"33.9","Tissue RNA - vagina [nTPM]":"40.4","Tissue RNA - white matter [nTPM]":"16.2","Cell RNA - A-431 [nTPM]":"59.2","Cell RNA - A549 [nTPM]":"10.9","Cell RNA - AF22 [nTPM]":"37.7","Cell RNA - AN3-CA [nTPM]":"24.0","Cell RNA - ASC diff [nTPM]":"28.3","Cell RNA - ASC TERT1 [nTPM]":"30.6","Cell RNA - BEWO [nTPM]":"45.6","Cell RNA - BJ [nTPM]":"56.3","Cell RNA - BJ hTERT+ [nTPM]":"55.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"52.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"70.1","Cell RNA - CACO-2 [nTPM]":"12.0","Cell RNA - CAPAN-2 [nTPM]":"19.9","Cell RNA - Daudi [nTPM]":"18.8","Cell RNA - EFO-21 [nTPM]":"23.5","Cell RNA - fHDF\/TERT166 [nTPM]":"26.9","Cell RNA - GAMG [nTPM]":"53.8","Cell RNA - HaCaT [nTPM]":"31.6","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"14.5","Cell RNA - HBF TERT88 [nTPM]":"45.6","Cell RNA - HDLM-2 [nTPM]":"60.9","Cell RNA - HEK 293 [nTPM]":"31.6","Cell RNA - HEL [nTPM]":"44.1","Cell RNA - HeLa [nTPM]":"33.0","Cell RNA - Hep G2 [nTPM]":"13.9","Cell RNA - HHSteC [nTPM]":"126.0","Cell RNA - HL-60 [nTPM]":"35.6","Cell RNA - HMC-1 [nTPM]":"50.1","Cell RNA - HSkMC [nTPM]":"35.1","Cell RNA - hTCEpi [nTPM]":"160.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.5","Cell RNA - hTERT-HME1 [nTPM]":"181.4","Cell RNA - hTERT-RPE1 [nTPM]":"35.1","Cell RNA - HUVEC TERT2 [nTPM]":"20.5","Cell RNA - JURKAT [nTPM]":"25.7","Cell RNA - K-562 [nTPM]":"77.1","Cell RNA - Karpas-707 [nTPM]":"107.8","Cell RNA - LHCN-M2 [nTPM]":"26.2","Cell RNA - MCF7 [nTPM]":"13.9","Cell RNA - MOLT-4 [nTPM]":"23.4","Cell RNA - NB-4 [nTPM]":"45.1","Cell RNA - NTERA-2 [nTPM]":"10.6","Cell RNA - OE19 [nTPM]":"41.2","Cell RNA - PC-3 [nTPM]":"14.8","Cell RNA - REH [nTPM]":"19.4","Cell RNA - RH-30 [nTPM]":"29.5","Cell RNA - RPMI-8226 [nTPM]":"17.5","Cell RNA - RPTEC TERT1 [nTPM]":"24.0","Cell RNA - RT4 [nTPM]":"25.8","Cell RNA - SCLC-21H [nTPM]":"33.1","Cell RNA - SH-SY5Y [nTPM]":"32.4","Cell RNA - SiHa [nTPM]":"19.5","Cell RNA - SK-BR-3 [nTPM]":"14.0","Cell RNA - SK-MEL-30 [nTPM]":"72.5","Cell RNA - SuSa [nTPM]":"19.0","Cell RNA - T-47d [nTPM]":"30.3","Cell RNA - THP-1 [nTPM]":"37.3","Cell RNA - TIME [nTPM]":"34.8","Cell RNA - U-138 MG [nTPM]":"27.2","Cell RNA - U-2 OS [nTPM]":"33.2","Cell RNA - U-2197 [nTPM]":"20.5","Cell RNA - U-251 MG [nTPM]":"38.3","Cell RNA - U-266\/70 [nTPM]":"70.8","Cell RNA - U-266\/84 [nTPM]":"38.2","Cell RNA - U-698 [nTPM]":"26.7","Cell RNA - U-87 MG [nTPM]":"45.4","Cell RNA - U-937 [nTPM]":"26.0","Cell RNA - WM-115 [nTPM]":"27.5","Blood RNA - basophil [nTPM]":"5.4","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"14.5","Brain RNA - basal ganglia [nTPM]":"15.3","Brain RNA - cerebellum [nTPM]":"16.5","Brain RNA - cerebral cortex [nTPM]":"17.9","Brain RNA - hippocampal formation [nTPM]":"14.4","Brain RNA - hypothalamus [nTPM]":"15.0","Brain RNA - medulla oblongata [nTPM]":"17.5","Brain RNA - midbrain [nTPM]":"16.7","Brain RNA - pons [nTPM]":"15.6","Brain RNA - spinal cord [nTPM]":"14.3","Brain RNA - thalamus [nTPM]":"17.0","Brain RNA - white matter [nTPM]":"16.2","Single Cell Type RNA - Adipocytes [nTPM]":"19.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.8","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.1","Single Cell Type RNA - Early spermatids [nTPM]":"17.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.8","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"5.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.6","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"47.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"16.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"10.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.4","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.7","Single Cell Type RNA - Paneth cells [nTPM]":"13.4","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"2.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.8","Single Cell Type RNA - Spermatocytes [nTPM]":"7.1","Single Cell Type RNA - Spermatogonia [nTPM]":"8.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"GUCA1A","Gene synonym":["C6orf131","COD3","CORD14","dJ139D8.6","GCAP","GCAP1","GUCA","GUCA1"],"Ensembl":"ENSG00000048545","Gene description":"Guanylate cyclase activator 1A","Uniprot":["P43080"],"Chromosome":"6","Position":"42155406-42181338","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"91","RNA tissue specific nTPM":{"retina":"804.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"667.2","Late spermatids":"432.4","Muller glia cells":"219.9","Rod photoreceptor cells":"1191.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"testis cancer":"3.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"plasmacytoid DC":"4.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"4.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"NTERA-2":"3.8","SH-SY5Y":"4.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005561","HPA075056"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA005561":"AB_2667361","HPA075056":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"804.8","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"8.8","Tissue RNA - thalamus [nTPM]":"6.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"4.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"4.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"6.2","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"140.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"667.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"106.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"65.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"432.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"5.2","Single Cell Type RNA - Muller glia cells [nTPM]":"219.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1191.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GUCA1B","Gene synonym":["GCAP2","RP48"],"Ensembl":"ENSG00000112599","Gene description":"Guanylate cyclase activator 1B","Uniprot":["Q9UMX6"],"Chromosome":"6","Position":"42183284-42194956","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"99","RNA tissue specific nTPM":{"retina":"466.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"23.2","Cone photoreceptor cells":"83.4","Oligodendrocytes":"28.2","Rod photoreceptor cells":"53.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"4.3","U-698":"3.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055479"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055479":"AB_2732598"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"3.8","Tissue RNA - cerebral cortex [nTPM]":"4.1","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"466.0","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"1.6","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"1.5","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"4.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"1.2","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"2.7","Cell RNA - U-266\/84 [nTPM]":"1.3","Cell RNA - U-698 [nTPM]":"3.9","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"3.8","Brain RNA - cerebral cortex [nTPM]":"4.1","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"83.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"8.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"GUCY2D","Gene synonym":["CORD6","CYGD","GUC1A4","GUC2D","LCA","LCA1","retGC","RETGC-1","ROS-GC1"],"Ensembl":"ENSG00000132518","Gene description":"Guanylate cyclase 2D, retinal","Uniprot":["Q02846"],"Chromosome":"17","Position":"8002615-8020342","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["cGMP biosynthesis","Sensory transduction","Vision"],"Molecular function":["Lyase"],"Disease involvement":["Cone-rod dystrophy","Congenital stationary night blindness","Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"retina":"34.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"62.6","Rod photoreceptor cells":"58.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"31","RNA blood cell specific nTPM":{"plasmacytoid DC":"8.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"50","RNA blood lineage specific nTPM":{"dendritic cells":"8.0"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"JURKAT":"5.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"34.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"5.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"8.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"14.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"GUF1","Gene synonym":["FLJ13220"],"Ensembl":"ENSG00000151806","Gene description":"GUF1 homolog, GTPase","Uniprot":["Q8N442"],"Chromosome":"4","Position":"44678420-44700928","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003934","HPA024222"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA003934":"AB_1079034","HPA024222":"AB_2671488"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.66e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.65e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"3.9","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"6.3","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"4.3","Tissue RNA - cerebral cortex [nTPM]":"3.6","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"3.8","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"4.1","Tissue RNA - gallbladder [nTPM]":"2.7","Tissue RNA - heart muscle [nTPM]":"6.1","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"7.1","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"4.9","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"4.9","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"6.7","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"15.8","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"4.8","Tissue RNA - stomach 1 [nTPM]":"7.9","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"2.2","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"17.0","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"3.9","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"11.9","Cell RNA - A549 [nTPM]":"6.0","Cell RNA - AF22 [nTPM]":"10.9","Cell RNA - AN3-CA [nTPM]":"13.9","Cell RNA - ASC diff [nTPM]":"4.4","Cell RNA - ASC TERT1 [nTPM]":"9.0","Cell RNA - BEWO [nTPM]":"24.0","Cell RNA - BJ [nTPM]":"16.1","Cell RNA - BJ hTERT+ [nTPM]":"8.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.4","Cell RNA - CACO-2 [nTPM]":"10.5","Cell RNA - CAPAN-2 [nTPM]":"8.3","Cell RNA - Daudi [nTPM]":"25.8","Cell RNA - EFO-21 [nTPM]":"12.3","Cell RNA - fHDF\/TERT166 [nTPM]":"7.7","Cell RNA - GAMG [nTPM]":"14.9","Cell RNA - HaCaT [nTPM]":"9.2","Cell RNA - HAP1 [nTPM]":"18.7","Cell RNA - HBEC3-KT [nTPM]":"18.2","Cell RNA - HBF TERT88 [nTPM]":"18.2","Cell RNA - HDLM-2 [nTPM]":"8.7","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"30.7","Cell RNA - HeLa [nTPM]":"5.3","Cell RNA - Hep G2 [nTPM]":"7.2","Cell RNA - HHSteC [nTPM]":"14.3","Cell RNA - HL-60 [nTPM]":"33.4","Cell RNA - HMC-1 [nTPM]":"12.7","Cell RNA - HSkMC [nTPM]":"9.2","Cell RNA - hTCEpi [nTPM]":"8.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.1","Cell RNA - hTERT-HME1 [nTPM]":"10.5","Cell RNA - hTERT-RPE1 [nTPM]":"7.6","Cell RNA - HUVEC TERT2 [nTPM]":"11.8","Cell RNA - JURKAT [nTPM]":"15.0","Cell RNA - K-562 [nTPM]":"31.7","Cell RNA - Karpas-707 [nTPM]":"4.9","Cell RNA - LHCN-M2 [nTPM]":"13.2","Cell RNA - MCF7 [nTPM]":"5.9","Cell RNA - MOLT-4 [nTPM]":"19.1","Cell RNA - NB-4 [nTPM]":"7.0","Cell RNA - NTERA-2 [nTPM]":"7.0","Cell RNA - OE19 [nTPM]":"8.5","Cell RNA - PC-3 [nTPM]":"13.8","Cell RNA - REH [nTPM]":"13.5","Cell RNA - RH-30 [nTPM]":"22.5","Cell RNA - RPMI-8226 [nTPM]":"11.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.8","Cell RNA - RT4 [nTPM]":"4.6","Cell RNA - SCLC-21H [nTPM]":"14.8","Cell RNA - SH-SY5Y [nTPM]":"11.1","Cell RNA - SiHa [nTPM]":"10.1","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"11.2","Cell RNA - SuSa [nTPM]":"8.4","Cell RNA - T-47d [nTPM]":"6.8","Cell RNA - THP-1 [nTPM]":"9.6","Cell RNA - TIME [nTPM]":"11.7","Cell RNA - U-138 MG [nTPM]":"11.0","Cell RNA - U-2 OS [nTPM]":"12.7","Cell RNA - U-2197 [nTPM]":"14.8","Cell RNA - U-251 MG [nTPM]":"19.1","Cell RNA - U-266\/70 [nTPM]":"17.9","Cell RNA - U-266\/84 [nTPM]":"17.4","Cell RNA - U-698 [nTPM]":"18.3","Cell RNA - U-87 MG [nTPM]":"11.9","Cell RNA - U-937 [nTPM]":"19.7","Cell RNA - WM-115 [nTPM]":"9.6","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"2.9","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"2.3","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"3.6","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"4.3","Brain RNA - cerebral cortex [nTPM]":"3.6","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.2","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"7.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.5","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"11.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"10.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"9.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.1","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"10.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"14.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.6","Single Cell Type RNA - Fibroblasts [nTPM]":"9.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"16.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"13.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.4","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.7","Single Cell Type RNA - Langerhans cells [nTPM]":"5.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"9.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"9.2","Single Cell Type RNA - Muller glia cells [nTPM]":"9.2","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.6","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"13.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.0","Single Cell Type RNA - Spermatocytes [nTPM]":"12.3","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.4","Single Cell Type RNA - T-cells [nTPM]":"9.5","Single Cell Type RNA - Theca cells [nTPM]":"18.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.3","Single Cell Type RNA - Urothelial cells [nTPM]":"10.6"},{"Gene":"HACE1","Gene synonym":["KIAA1320"],"Ensembl":"ENSG00000085382","Gene description":"HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1","Uniprot":["Q8IYU2"],"Chromosome":"6","Position":"104728094-104859919","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"30.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"45.9","Excitatory neurons":"118.8","Inhibitory neurons":"84.2","Microglial cells":"45.9","Oligodendrocyte precursor cells":"64.3","Oligodendrocytes":"74.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046071"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA046071":"AB_2679524"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.50e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"3.2","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"4.8","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"3.6","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"30.6","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"3.7","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"11.5","Tissue RNA - salivary gland [nTPM]":"2.9","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"2.5","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"4.5","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"3.3","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"2.7","Cell RNA - AF22 [nTPM]":"11.3","Cell RNA - AN3-CA [nTPM]":"14.3","Cell RNA - ASC diff [nTPM]":"6.6","Cell RNA - ASC TERT1 [nTPM]":"8.8","Cell RNA - BEWO [nTPM]":"13.3","Cell RNA - BJ [nTPM]":"7.7","Cell RNA - BJ hTERT+ [nTPM]":"11.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.2","Cell RNA - CACO-2 [nTPM]":"2.5","Cell RNA - CAPAN-2 [nTPM]":"2.3","Cell RNA - Daudi [nTPM]":"2.2","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"8.1","Cell RNA - HaCaT [nTPM]":"2.6","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"5.3","Cell RNA - HBF TERT88 [nTPM]":"10.0","Cell RNA - HDLM-2 [nTPM]":"9.1","Cell RNA - HEK 293 [nTPM]":"7.2","Cell RNA - HEL [nTPM]":"7.7","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"6.8","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"5.9","Cell RNA - hTCEpi [nTPM]":"4.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"5.2","Cell RNA - hTERT-RPE1 [nTPM]":"6.3","Cell RNA - HUVEC TERT2 [nTPM]":"8.0","Cell RNA - JURKAT [nTPM]":"9.2","Cell RNA - K-562 [nTPM]":"7.6","Cell RNA - Karpas-707 [nTPM]":"2.4","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"5.1","Cell RNA - NB-4 [nTPM]":"4.1","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"2.6","Cell RNA - REH [nTPM]":"8.0","Cell RNA - RH-30 [nTPM]":"12.8","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"3.8","Cell RNA - RT4 [nTPM]":"6.6","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"9.1","Cell RNA - SiHa [nTPM]":"4.2","Cell RNA - SK-BR-3 [nTPM]":"4.3","Cell RNA - SK-MEL-30 [nTPM]":"2.3","Cell RNA - SuSa [nTPM]":"7.3","Cell RNA - T-47d [nTPM]":"2.7","Cell RNA - THP-1 [nTPM]":"9.2","Cell RNA - TIME [nTPM]":"8.5","Cell RNA - U-138 MG [nTPM]":"3.9","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"10.5","Cell RNA - U-251 MG [nTPM]":"7.4","Cell RNA - U-266\/70 [nTPM]":"3.5","Cell RNA - U-266\/84 [nTPM]":"4.1","Cell RNA - U-698 [nTPM]":"7.6","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"7.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"4.8","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"11.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"42.4","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.6","Single Cell Type RNA - dendritic cells [nTPM]":"4.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"6.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"12.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"118.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.7","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"84.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"3.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"4.3","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"64.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"74.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"2.9","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"3.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"13.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"6.2","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"HARS1","Gene synonym":["HARS","HisRS","USH3B"],"Ensembl":"ENSG00000170445","Gene description":"Histidyl-tRNA synthetase 1","Uniprot":["P12081"],"Chromosome":"5","Position":"140673035-140691537","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Disease variant","Neurodegeneration","Neuropathy","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"41.4","dendritic cells":"11.5","Extravillous trophoblasts":"48.6","Hofbauer cells":"35.7","Syncytiotrophoblasts":"36.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036539"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036539":"AB_10669796"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"31.6","Tissue RNA - adrenal gland [nTPM]":"39.9","Tissue RNA - amygdala [nTPM]":"64.8","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"67.0","Tissue RNA - bone marrow [nTPM]":"24.3","Tissue RNA - breast [nTPM]":"29.3","Tissue RNA - cerebellum [nTPM]":"64.9","Tissue RNA - cerebral cortex [nTPM]":"88.7","Tissue RNA - cervix [nTPM]":"32.9","Tissue RNA - choroid plexus [nTPM]":"57.9","Tissue RNA - colon [nTPM]":"39.2","Tissue RNA - duodenum [nTPM]":"21.8","Tissue RNA - endometrium 1 [nTPM]":"34.5","Tissue RNA - epididymis [nTPM]":"27.1","Tissue RNA - esophagus [nTPM]":"42.9","Tissue RNA - fallopian tube [nTPM]":"30.8","Tissue RNA - gallbladder [nTPM]":"21.0","Tissue RNA - heart muscle [nTPM]":"38.3","Tissue RNA - hippocampal formation [nTPM]":"67.8","Tissue RNA - hypothalamus [nTPM]":"72.2","Tissue RNA - kidney [nTPM]":"30.7","Tissue RNA - liver [nTPM]":"47.3","Tissue RNA - lung [nTPM]":"27.2","Tissue RNA - lymph node [nTPM]":"29.6","Tissue RNA - medulla oblongata [nTPM]":"71.2","Tissue RNA - midbrain [nTPM]":"69.9","Tissue RNA - ovary [nTPM]":"31.3","Tissue RNA - pancreas [nTPM]":"40.8","Tissue RNA - parathyroid gland [nTPM]":"37.1","Tissue RNA - pituitary gland [nTPM]":"60.0","Tissue RNA - placenta [nTPM]":"18.5","Tissue RNA - pons [nTPM]":"72.8","Tissue RNA - prostate [nTPM]":"33.0","Tissue RNA - rectum [nTPM]":"29.6","Tissue RNA - retina [nTPM]":"18.5","Tissue RNA - salivary gland [nTPM]":"29.2","Tissue RNA - seminal vesicle [nTPM]":"32.0","Tissue RNA - skeletal muscle [nTPM]":"56.7","Tissue RNA - skin 1 [nTPM]":"53.9","Tissue RNA - small intestine [nTPM]":"28.6","Tissue RNA - smooth muscle [nTPM]":"35.2","Tissue RNA - spinal cord [nTPM]":"62.1","Tissue RNA - spleen [nTPM]":"32.2","Tissue RNA - stomach 1 [nTPM]":"36.0","Tissue RNA - testis [nTPM]":"25.6","Tissue RNA - thalamus [nTPM]":"77.4","Tissue RNA - thymus [nTPM]":"32.2","Tissue RNA - thyroid gland [nTPM]":"27.1","Tissue RNA - tongue [nTPM]":"33.4","Tissue RNA - tonsil [nTPM]":"36.8","Tissue RNA - urinary bladder [nTPM]":"34.3","Tissue RNA - vagina [nTPM]":"32.0","Tissue RNA - white matter [nTPM]":"71.9","Cell RNA - A-431 [nTPM]":"66.8","Cell RNA - A549 [nTPM]":"94.3","Cell RNA - AF22 [nTPM]":"55.5","Cell RNA - AN3-CA [nTPM]":"120.5","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"74.9","Cell RNA - BEWO [nTPM]":"57.9","Cell RNA - BJ [nTPM]":"104.8","Cell RNA - BJ hTERT+ [nTPM]":"75.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"118.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"109.4","Cell RNA - CACO-2 [nTPM]":"174.8","Cell RNA - CAPAN-2 [nTPM]":"54.1","Cell RNA - Daudi [nTPM]":"88.4","Cell RNA - EFO-21 [nTPM]":"90.3","Cell RNA - fHDF\/TERT166 [nTPM]":"118.3","Cell RNA - GAMG [nTPM]":"94.3","Cell RNA - HaCaT [nTPM]":"66.6","Cell RNA - HAP1 [nTPM]":"85.9","Cell RNA - HBEC3-KT [nTPM]":"169.2","Cell RNA - HBF TERT88 [nTPM]":"111.6","Cell RNA - HDLM-2 [nTPM]":"74.5","Cell RNA - HEK 293 [nTPM]":"105.0","Cell RNA - HEL [nTPM]":"63.7","Cell RNA - HeLa [nTPM]":"115.4","Cell RNA - Hep G2 [nTPM]":"111.8","Cell RNA - HHSteC [nTPM]":"86.3","Cell RNA - HL-60 [nTPM]":"101.1","Cell RNA - HMC-1 [nTPM]":"49.8","Cell RNA - HSkMC [nTPM]":"80.4","Cell RNA - hTCEpi [nTPM]":"51.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"129.0","Cell RNA - hTERT-HME1 [nTPM]":"72.6","Cell RNA - hTERT-RPE1 [nTPM]":"69.5","Cell RNA - HUVEC TERT2 [nTPM]":"122.1","Cell RNA - JURKAT [nTPM]":"52.2","Cell RNA - K-562 [nTPM]":"56.5","Cell RNA - Karpas-707 [nTPM]":"68.6","Cell RNA - LHCN-M2 [nTPM]":"125.6","Cell RNA - MCF7 [nTPM]":"111.0","Cell RNA - MOLT-4 [nTPM]":"71.8","Cell RNA - NB-4 [nTPM]":"100.6","Cell RNA - NTERA-2 [nTPM]":"43.3","Cell RNA - OE19 [nTPM]":"52.3","Cell RNA - PC-3 [nTPM]":"60.9","Cell RNA - REH [nTPM]":"65.4","Cell RNA - RH-30 [nTPM]":"82.0","Cell RNA - RPMI-8226 [nTPM]":"70.9","Cell RNA - RPTEC TERT1 [nTPM]":"97.0","Cell RNA - RT4 [nTPM]":"82.2","Cell RNA - SCLC-21H [nTPM]":"86.5","Cell RNA - SH-SY5Y [nTPM]":"83.7","Cell RNA - SiHa [nTPM]":"86.1","Cell RNA - SK-BR-3 [nTPM]":"121.5","Cell RNA - SK-MEL-30 [nTPM]":"84.2","Cell RNA - SuSa [nTPM]":"54.9","Cell RNA - T-47d [nTPM]":"89.5","Cell RNA - THP-1 [nTPM]":"55.5","Cell RNA - TIME [nTPM]":"100.3","Cell RNA - U-138 MG [nTPM]":"107.8","Cell RNA - U-2 OS [nTPM]":"41.6","Cell RNA - U-2197 [nTPM]":"61.5","Cell RNA - U-251 MG [nTPM]":"144.7","Cell RNA - U-266\/70 [nTPM]":"68.5","Cell RNA - U-266\/84 [nTPM]":"90.5","Cell RNA - U-698 [nTPM]":"89.4","Cell RNA - U-87 MG [nTPM]":"82.8","Cell RNA - U-937 [nTPM]":"83.1","Cell RNA - WM-115 [nTPM]":"76.1","Blood RNA - basophil [nTPM]":"16.2","Blood RNA - classical monocyte [nTPM]":"31.2","Blood RNA - eosinophil [nTPM]":"24.0","Blood RNA - gdT-cell [nTPM]":"61.0","Blood RNA - intermediate monocyte [nTPM]":"46.3","Blood RNA - MAIT T-cell [nTPM]":"54.2","Blood RNA - memory B-cell [nTPM]":"34.9","Blood RNA - memory CD4 T-cell [nTPM]":"54.1","Blood RNA - memory CD8 T-cell [nTPM]":"57.6","Blood RNA - myeloid DC [nTPM]":"48.5","Blood RNA - naive B-cell [nTPM]":"34.6","Blood RNA - naive CD4 T-cell [nTPM]":"58.1","Blood RNA - naive CD8 T-cell [nTPM]":"55.4","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"59.3","Blood RNA - non-classical monocyte [nTPM]":"54.9","Blood RNA - plasmacytoid DC [nTPM]":"34.3","Blood RNA - T-reg [nTPM]":"51.3","Blood RNA - total PBMC [nTPM]":"56.7","Brain RNA - amygdala [nTPM]":"64.8","Brain RNA - basal ganglia [nTPM]":"67.0","Brain RNA - cerebellum [nTPM]":"64.9","Brain RNA - cerebral cortex [nTPM]":"88.7","Brain RNA - hippocampal formation [nTPM]":"67.8","Brain RNA - hypothalamus [nTPM]":"72.2","Brain RNA - medulla oblongata [nTPM]":"71.2","Brain RNA - midbrain [nTPM]":"69.9","Brain RNA - pons [nTPM]":"72.8","Brain RNA - spinal cord [nTPM]":"62.1","Brain RNA - thalamus [nTPM]":"77.4","Brain RNA - white matter [nTPM]":"71.9","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.6","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"HCN1","Gene synonym":["BCNG-1","BCNG1","HAC-2"],"Ensembl":"ENSG00000164588","Gene description":"Hyperpolarization activated cyclic nucleotide gated potassium channel 1","Uniprot":["O60741"],"Chromosome":"5","Position":"45254948-45696498","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Potassium channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"7.2","retina":"17.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"671.7","Inhibitory neurons":"766.5","Rod photoreceptor cells":"199.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"7.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"WM-115":"1.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019195"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019195":"AB_2670094"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"7.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"17.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"7.2","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"29.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"133.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"671.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"766.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"14.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"199.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"HCRT","Gene synonym":["OX","PPOX"],"Ensembl":"ENSG00000161610","Gene description":"Hypocretin neuropeptide precursor","Uniprot":["O43612"],"Chromosome":"17","Position":"42184060-42185452","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Neuropeptide"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"1067","RNA tissue specific nTPM":{"brain":"384.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"1.8","Enteroendocrine cells":"3.0","Kupffer cells":"1.6","Oligodendrocyte precursor cells":"2.0","Proximal enterocytes":"1.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.5"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"hypothalamus":"384.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"hypothalamus":"93.5"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"21","RNA pig brain regional specific nTPM":{"hypothalamus":"25.3"},"Antibody":["HPA064801","CAB079778"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 58: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079778":null,"HPA064801":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-5"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"384.8","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"52.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"384.8","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"52.6","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"HEPACAM","Gene synonym":["FLJ25530","GLIALCAM"],"Ensembl":"ENSG00000165478","Gene description":"Hepatic and glial cell adhesion molecule","Uniprot":["Q14CZ8"],"Chromosome":"11","Position":"124919205-124936412","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Cell cycle","Growth arrest","Growth regulation"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"222.6","choroid plexus":"79.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Astrocytes":"184.8","Oligodendrocyte precursor cells":"72.9","Oligodendrocytes":"163.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"glioma":"29.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"30","RNA cell line specific nTPM":{"Hep G2":"25.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017613","CAB025486"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB025486":null,"HPA017613":"AB_1850595"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"172.8","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"203.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"170.4","Tissue RNA - cerebral cortex [nTPM]":"162.1","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"79.7","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"163.2","Tissue RNA - hypothalamus [nTPM]":"156.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"16.2","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"222.6","Tissue RNA - midbrain [nTPM]":"182.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"183.6","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"205.7","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"182.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"212.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"25.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"172.8","Brain RNA - basal ganglia [nTPM]":"203.3","Brain RNA - cerebellum [nTPM]":"170.4","Brain RNA - cerebral cortex [nTPM]":"162.1","Brain RNA - hippocampal formation [nTPM]":"163.2","Brain RNA - hypothalamus [nTPM]":"156.1","Brain RNA - medulla oblongata [nTPM]":"222.6","Brain RNA - midbrain [nTPM]":"182.8","Brain RNA - pons [nTPM]":"183.6","Brain RNA - spinal cord [nTPM]":"205.7","Brain RNA - thalamus [nTPM]":"182.0","Brain RNA - white matter [nTPM]":"212.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"184.8","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"11.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"72.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"163.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"HGF","Gene synonym":["DFNB39","F-TCF","HGFB","HPTA","SF"],"Ensembl":"ENSG00000019991","Gene description":"Hepatocyte growth factor","Uniprot":["P14210"],"Chromosome":"7","Position":"81699010-81770438","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor","Serine protease homolog"],"Disease involvement":["Cancer-related genes","Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"placenta":"311.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"23.8","Fibroblasts":"95.8","Hepatic stellate cells":"25.0","Muller glia cells":"36.2","Smooth muscle cells":"26.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"94.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"94.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"171.6","HHSteC":"135.8","HL-60":"82.4","hTEC\/SVTERT24-B":"87.4","Karpas-707":"240.7","U-87 MG":"62.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010333","HPA040360","HPA044088"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":4110000,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010333":"AB_647965","HPA040360":"AB_2676939","HPA044088":"AB_2678804"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"19.8","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"3.3","Tissue RNA - bone marrow [nTPM]":"12.3","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"7.2","Tissue RNA - choroid plexus [nTPM]":"1.8","Tissue RNA - colon [nTPM]":"4.4","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"3.6","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"16.6","Tissue RNA - heart muscle [nTPM]":"4.7","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"11.8","Tissue RNA - liver [nTPM]":"30.3","Tissue RNA - lung [nTPM]":"19.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"311.9","Tissue RNA - pons [nTPM]":"4.3","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"6.4","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"2.3","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"3.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"21.6","Cell RNA - ASC TERT1 [nTPM]":"171.6","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"33.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"6.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"135.8","Cell RNA - HL-60 [nTPM]":"82.4","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"41.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"87.4","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"2.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"240.7","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"56.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"9.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"2.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"62.6","Cell RNA - U-937 [nTPM]":"16.9","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"94.0","Blood RNA - classical monocyte [nTPM]":"15.2","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"18.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"17.3","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"4.3","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"3.3","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"4.3","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"3.3","Single Cell Type RNA - Adipocytes [nTPM]":"6.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"15.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.9","Single Cell Type RNA - Fibroblasts [nTPM]":"95.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"14.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"36.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"HGSNAT","Gene synonym":["FLJ32731","HGNAT","TMEM76"],"Ensembl":"ENSG00000165102","Gene description":"Heparan-alpha-glucosaminide N-acetyltransferase","Uniprot":["Q68CP4"],"Chromosome":"8","Position":"43140464-43202855","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029578"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029578":"AB_10602423"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.33e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.3","Tissue RNA - adrenal gland [nTPM]":"20.0","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"21.7","Tissue RNA - breast [nTPM]":"27.8","Tissue RNA - cerebellum [nTPM]":"10.6","Tissue RNA - cerebral cortex [nTPM]":"13.5","Tissue RNA - cervix [nTPM]":"35.0","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"25.4","Tissue RNA - duodenum [nTPM]":"18.4","Tissue RNA - endometrium 1 [nTPM]":"30.1","Tissue RNA - epididymis [nTPM]":"30.6","Tissue RNA - esophagus [nTPM]":"24.0","Tissue RNA - fallopian tube [nTPM]":"29.0","Tissue RNA - gallbladder [nTPM]":"25.9","Tissue RNA - heart muscle [nTPM]":"23.3","Tissue RNA - hippocampal formation [nTPM]":"13.3","Tissue RNA - hypothalamus [nTPM]":"17.6","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"26.6","Tissue RNA - lung [nTPM]":"24.5","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"13.3","Tissue RNA - midbrain [nTPM]":"12.0","Tissue RNA - ovary [nTPM]":"35.9","Tissue RNA - pancreas [nTPM]":"29.9","Tissue RNA - parathyroid gland [nTPM]":"22.7","Tissue RNA - pituitary gland [nTPM]":"30.7","Tissue RNA - placenta [nTPM]":"28.4","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"26.9","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"23.3","Tissue RNA - skeletal muscle [nTPM]":"14.4","Tissue RNA - skin 1 [nTPM]":"35.4","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"25.1","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"17.6","Tissue RNA - stomach 1 [nTPM]":"23.2","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"15.8","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"26.9","Tissue RNA - tongue [nTPM]":"17.6","Tissue RNA - tonsil [nTPM]":"15.7","Tissue RNA - urinary bladder [nTPM]":"25.2","Tissue RNA - vagina [nTPM]":"28.7","Tissue RNA - white matter [nTPM]":"13.0","Cell RNA - A-431 [nTPM]":"27.4","Cell RNA - A549 [nTPM]":"36.0","Cell RNA - AF22 [nTPM]":"8.9","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"71.7","Cell RNA - ASC TERT1 [nTPM]":"53.8","Cell RNA - BEWO [nTPM]":"13.3","Cell RNA - BJ [nTPM]":"30.5","Cell RNA - BJ hTERT+ [nTPM]":"36.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.3","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"39.2","Cell RNA - Daudi [nTPM]":"14.8","Cell RNA - EFO-21 [nTPM]":"20.5","Cell RNA - fHDF\/TERT166 [nTPM]":"42.9","Cell RNA - GAMG [nTPM]":"15.2","Cell RNA - HaCaT [nTPM]":"15.5","Cell RNA - HAP1 [nTPM]":"4.0","Cell RNA - HBEC3-KT [nTPM]":"18.5","Cell RNA - HBF TERT88 [nTPM]":"12.7","Cell RNA - HDLM-2 [nTPM]":"6.4","Cell RNA - HEK 293 [nTPM]":"6.9","Cell RNA - HEL [nTPM]":"16.3","Cell RNA - HeLa [nTPM]":"22.2","Cell RNA - Hep G2 [nTPM]":"8.1","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"36.2","Cell RNA - hTCEpi [nTPM]":"25.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.7","Cell RNA - hTERT-HME1 [nTPM]":"24.9","Cell RNA - hTERT-RPE1 [nTPM]":"34.5","Cell RNA - HUVEC TERT2 [nTPM]":"39.2","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"7.5","Cell RNA - Karpas-707 [nTPM]":"22.1","Cell RNA - LHCN-M2 [nTPM]":"40.4","Cell RNA - MCF7 [nTPM]":"10.0","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"7.2","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"16.3","Cell RNA - PC-3 [nTPM]":"5.4","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"16.1","Cell RNA - RPMI-8226 [nTPM]":"7.7","Cell RNA - RPTEC TERT1 [nTPM]":"36.1","Cell RNA - RT4 [nTPM]":"22.8","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"39.0","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"17.4","Cell RNA - SuSa [nTPM]":"19.0","Cell RNA - T-47d [nTPM]":"43.7","Cell RNA - THP-1 [nTPM]":"20.9","Cell RNA - TIME [nTPM]":"46.3","Cell RNA - U-138 MG [nTPM]":"33.2","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"20.9","Cell RNA - U-251 MG [nTPM]":"12.7","Cell RNA - U-266\/70 [nTPM]":"17.9","Cell RNA - U-266\/84 [nTPM]":"18.2","Cell RNA - U-698 [nTPM]":"6.1","Cell RNA - U-87 MG [nTPM]":"26.8","Cell RNA - U-937 [nTPM]":"6.3","Cell RNA - WM-115 [nTPM]":"20.8","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"8.8","Blood RNA - eosinophil [nTPM]":"9.4","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"5.4","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"15.8","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"8.8","Blood RNA - non-classical monocyte [nTPM]":"8.6","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"5.0","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"10.6","Brain RNA - cerebral cortex [nTPM]":"13.5","Brain RNA - hippocampal formation [nTPM]":"13.3","Brain RNA - hypothalamus [nTPM]":"17.6","Brain RNA - medulla oblongata [nTPM]":"13.3","Brain RNA - midbrain [nTPM]":"12.0","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"15.8","Brain RNA - white matter [nTPM]":"13.0","Single Cell Type RNA - Adipocytes [nTPM]":"39.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.9","Single Cell Type RNA - Astrocytes [nTPM]":"48.0","Single Cell Type RNA - B-cells [nTPM]":"26.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"50.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"17.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.2","Single Cell Type RNA - dendritic cells [nTPM]":"30.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"26.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.1","Single Cell Type RNA - Endothelial cells [nTPM]":"37.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.1","Single Cell Type RNA - Erythroid cells [nTPM]":"15.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.4","Single Cell Type RNA - Fibroblasts [nTPM]":"34.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.5","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"51.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"23.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.2","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"34.3","Single Cell Type RNA - Langerhans cells [nTPM]":"58.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"35.1","Single Cell Type RNA - Macrophages [nTPM]":"43.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"33.5","Single Cell Type RNA - Muller glia cells [nTPM]":"13.5","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.9","Single Cell Type RNA - Paneth cells [nTPM]":"17.0","Single Cell Type RNA - Peritubular cells [nTPM]":"31.6","Single Cell Type RNA - Plasma cells [nTPM]":"19.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.1","Single Cell Type RNA - T-cells [nTPM]":"25.0","Single Cell Type RNA - Theca cells [nTPM]":"37.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.7"},{"Gene":"HINT1","Gene synonym":["HINT","PKCI-1","PRKCNH1"],"Ensembl":"ENSG00000169567","Gene description":"Histidine triad nucleotide binding protein 1","Uniprot":["P49773"],"Chromosome":"5","Position":"131155383-131224468","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"3537.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044577"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA044577":"AB_10795618"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Tissue RNA - adipose tissue [nTPM]":"132.6","Tissue RNA - adrenal gland [nTPM]":"175.0","Tissue RNA - amygdala [nTPM]":"235.7","Tissue RNA - appendix [nTPM]":"139.8","Tissue RNA - basal ganglia [nTPM]":"245.1","Tissue RNA - bone marrow [nTPM]":"259.3","Tissue RNA - breast [nTPM]":"172.7","Tissue RNA - cerebellum [nTPM]":"241.6","Tissue RNA - cerebral cortex [nTPM]":"326.2","Tissue RNA - cervix [nTPM]":"117.6","Tissue RNA - choroid plexus [nTPM]":"243.8","Tissue RNA - colon [nTPM]":"227.6","Tissue RNA - duodenum [nTPM]":"176.1","Tissue RNA - endometrium 1 [nTPM]":"119.6","Tissue RNA - epididymis [nTPM]":"187.5","Tissue RNA - esophagus [nTPM]":"181.3","Tissue RNA - fallopian tube [nTPM]":"165.6","Tissue RNA - gallbladder [nTPM]":"108.0","Tissue RNA - heart muscle [nTPM]":"167.2","Tissue RNA - hippocampal formation [nTPM]":"245.9","Tissue RNA - hypothalamus [nTPM]":"247.8","Tissue RNA - kidney [nTPM]":"256.7","Tissue RNA - liver [nTPM]":"474.2","Tissue RNA - lung [nTPM]":"119.0","Tissue RNA - lymph node [nTPM]":"206.5","Tissue RNA - medulla oblongata [nTPM]":"241.6","Tissue RNA - midbrain [nTPM]":"237.2","Tissue RNA - ovary [nTPM]":"121.5","Tissue RNA - pancreas [nTPM]":"165.5","Tissue RNA - parathyroid gland [nTPM]":"285.6","Tissue RNA - pituitary gland [nTPM]":"152.5","Tissue RNA - placenta [nTPM]":"87.5","Tissue RNA - pons [nTPM]":"249.1","Tissue RNA - prostate [nTPM]":"155.1","Tissue RNA - rectum [nTPM]":"226.5","Tissue RNA - retina [nTPM]":"110.8","Tissue RNA - salivary gland [nTPM]":"172.8","Tissue RNA - seminal vesicle [nTPM]":"116.4","Tissue RNA - skeletal muscle [nTPM]":"334.1","Tissue RNA - skin 1 [nTPM]":"170.0","Tissue RNA - small intestine [nTPM]":"196.3","Tissue RNA - smooth muscle [nTPM]":"124.2","Tissue RNA - spinal cord [nTPM]":"242.6","Tissue RNA - spleen [nTPM]":"126.9","Tissue RNA - stomach 1 [nTPM]":"136.5","Tissue RNA - testis [nTPM]":"80.1","Tissue RNA - thalamus [nTPM]":"240.8","Tissue RNA - thymus [nTPM]":"166.5","Tissue RNA - thyroid gland [nTPM]":"177.2","Tissue RNA - tongue [nTPM]":"278.4","Tissue RNA - tonsil [nTPM]":"192.3","Tissue RNA - urinary bladder [nTPM]":"152.9","Tissue RNA - vagina [nTPM]":"129.7","Tissue RNA - white matter [nTPM]":"245.3","Cell RNA - A-431 [nTPM]":"437.1","Cell RNA - A549 [nTPM]":"522.7","Cell RNA - AF22 [nTPM]":"448.2","Cell RNA - AN3-CA [nTPM]":"877.2","Cell RNA - ASC diff [nTPM]":"273.1","Cell RNA - ASC TERT1 [nTPM]":"297.1","Cell RNA - BEWO [nTPM]":"441.3","Cell RNA - BJ [nTPM]":"300.3","Cell RNA - BJ hTERT+ [nTPM]":"230.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"235.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"272.1","Cell RNA - CACO-2 [nTPM]":"547.1","Cell RNA - CAPAN-2 [nTPM]":"516.8","Cell RNA - Daudi [nTPM]":"563.3","Cell RNA - EFO-21 [nTPM]":"625.7","Cell RNA - fHDF\/TERT166 [nTPM]":"329.6","Cell RNA - GAMG [nTPM]":"569.1","Cell RNA - HaCaT [nTPM]":"253.4","Cell RNA - HAP1 [nTPM]":"315.4","Cell RNA - HBEC3-KT [nTPM]":"635.3","Cell RNA - HBF TERT88 [nTPM]":"244.1","Cell RNA - HDLM-2 [nTPM]":"500.0","Cell RNA - HEK 293 [nTPM]":"514.6","Cell RNA - HEL [nTPM]":"199.1","Cell RNA - HeLa [nTPM]":"814.0","Cell RNA - Hep G2 [nTPM]":"771.9","Cell RNA - HHSteC [nTPM]":"532.6","Cell RNA - HL-60 [nTPM]":"349.4","Cell RNA - HMC-1 [nTPM]":"65.4","Cell RNA - HSkMC [nTPM]":"400.1","Cell RNA - hTCEpi [nTPM]":"618.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"295.8","Cell RNA - hTERT-HME1 [nTPM]":"528.2","Cell RNA - hTERT-RPE1 [nTPM]":"533.7","Cell RNA - HUVEC TERT2 [nTPM]":"314.1","Cell RNA - JURKAT [nTPM]":"727.8","Cell RNA - K-562 [nTPM]":"313.4","Cell RNA - Karpas-707 [nTPM]":"1132.1","Cell RNA - LHCN-M2 [nTPM]":"338.8","Cell RNA - MCF7 [nTPM]":"419.9","Cell RNA - MOLT-4 [nTPM]":"548.0","Cell RNA - NB-4 [nTPM]":"945.6","Cell RNA - NTERA-2 [nTPM]":"415.6","Cell RNA - OE19 [nTPM]":"425.6","Cell RNA - PC-3 [nTPM]":"362.0","Cell RNA - REH [nTPM]":"407.9","Cell RNA - RH-30 [nTPM]":"436.1","Cell RNA - RPMI-8226 [nTPM]":"988.1","Cell RNA - RPTEC TERT1 [nTPM]":"500.6","Cell RNA - RT4 [nTPM]":"567.0","Cell RNA - SCLC-21H [nTPM]":"563.3","Cell RNA - SH-SY5Y [nTPM]":"351.9","Cell RNA - SiHa [nTPM]":"380.5","Cell RNA - SK-BR-3 [nTPM]":"243.5","Cell RNA - SK-MEL-30 [nTPM]":"612.0","Cell RNA - SuSa [nTPM]":"574.4","Cell RNA - T-47d [nTPM]":"291.2","Cell RNA - THP-1 [nTPM]":"520.8","Cell RNA - TIME [nTPM]":"396.0","Cell RNA - U-138 MG [nTPM]":"351.7","Cell RNA - U-2 OS [nTPM]":"244.0","Cell RNA - U-2197 [nTPM]":"323.0","Cell RNA - U-251 MG [nTPM]":"684.2","Cell RNA - U-266\/70 [nTPM]":"342.3","Cell RNA - U-266\/84 [nTPM]":"561.4","Cell RNA - U-698 [nTPM]":"578.8","Cell RNA - U-87 MG [nTPM]":"497.8","Cell RNA - U-937 [nTPM]":"586.8","Cell RNA - WM-115 [nTPM]":"346.3","Blood RNA - basophil [nTPM]":"179.8","Blood RNA - classical monocyte [nTPM]":"187.9","Blood RNA - eosinophil [nTPM]":"85.0","Blood RNA - gdT-cell [nTPM]":"196.3","Blood RNA - intermediate monocyte [nTPM]":"109.9","Blood RNA - MAIT T-cell [nTPM]":"298.0","Blood RNA - memory B-cell [nTPM]":"384.9","Blood RNA - memory CD4 T-cell [nTPM]":"462.0","Blood RNA - memory CD8 T-cell [nTPM]":"294.2","Blood RNA - myeloid DC [nTPM]":"396.9","Blood RNA - naive B-cell [nTPM]":"332.6","Blood RNA - naive CD4 T-cell [nTPM]":"416.0","Blood RNA - naive CD8 T-cell [nTPM]":"325.5","Blood RNA - neutrophil [nTPM]":"35.6","Blood RNA - NK-cell [nTPM]":"269.0","Blood RNA - non-classical monocyte [nTPM]":"128.0","Blood RNA - plasmacytoid DC [nTPM]":"521.4","Blood RNA - T-reg [nTPM]":"362.5","Blood RNA - total PBMC [nTPM]":"608.6","Brain RNA - amygdala [nTPM]":"235.7","Brain RNA - basal ganglia [nTPM]":"245.1","Brain RNA - cerebellum [nTPM]":"241.6","Brain RNA - cerebral cortex [nTPM]":"326.2","Brain RNA - hippocampal formation [nTPM]":"245.9","Brain RNA - hypothalamus [nTPM]":"247.8","Brain RNA - medulla oblongata [nTPM]":"241.6","Brain RNA - midbrain [nTPM]":"237.2","Brain RNA - pons [nTPM]":"249.1","Brain RNA - spinal cord [nTPM]":"242.6","Brain RNA - thalamus [nTPM]":"240.8","Brain RNA - white matter [nTPM]":"245.3","Single Cell Type RNA - Adipocytes [nTPM]":"582.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"282.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"279.1","Single Cell Type RNA - Astrocytes [nTPM]":"34.3","Single Cell Type RNA - B-cells [nTPM]":"718.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1301.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1472.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1928.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"889.5","Single Cell Type RNA - Bipolar cells [nTPM]":"191.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1134.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1831.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"517.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1028.0","Single Cell Type RNA - Club cells [nTPM]":"882.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"715.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"780.9","Single Cell Type RNA - dendritic cells [nTPM]":"641.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1245.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1663.0","Single Cell Type RNA - Ductal cells [nTPM]":"1024.5","Single Cell Type RNA - Early spermatids [nTPM]":"783.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"718.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"443.7","Single Cell Type RNA - Endothelial cells [nTPM]":"501.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"698.1","Single Cell Type RNA - Erythroid cells [nTPM]":"669.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"774.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1632.8","Single Cell Type RNA - Fibroblasts [nTPM]":"400.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"355.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"753.7","Single Cell Type RNA - granulocytes [nTPM]":"108.2","Single Cell Type RNA - Granulosa cells [nTPM]":"666.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"436.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2380.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"887.1","Single Cell Type RNA - Horizontal cells [nTPM]":"148.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"947.2","Single Cell Type RNA - Ionocytes [nTPM]":"915.5","Single Cell Type RNA - Kupffer cells [nTPM]":"472.4","Single Cell Type RNA - Langerhans cells [nTPM]":"906.9","Single Cell Type RNA - Late spermatids [nTPM]":"206.3","Single Cell Type RNA - Leydig cells [nTPM]":"392.4","Single Cell Type RNA - Macrophages [nTPM]":"447.0","Single Cell Type RNA - Melanocytes [nTPM]":"965.8","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"1269.4","Single Cell Type RNA - Muller glia cells [nTPM]":"405.1","Single Cell Type RNA - NK-cells [nTPM]":"488.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"55.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"894.3","Single Cell Type RNA - Paneth cells [nTPM]":"1094.2","Single Cell Type RNA - Peritubular cells [nTPM]":"418.6","Single Cell Type RNA - Plasma cells [nTPM]":"679.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1998.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1690.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3537.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"708.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"194.0","Single Cell Type RNA - Sertoli cells [nTPM]":"243.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"287.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"730.3","Single Cell Type RNA - Spermatocytes [nTPM]":"625.5","Single Cell Type RNA - Spermatogonia [nTPM]":"197.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1109.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1146.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"456.8","Single Cell Type RNA - T-cells [nTPM]":"671.1","Single Cell Type RNA - Theca cells [nTPM]":"464.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1280.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1713.2"},{"Gene":"HK1","Gene synonym":[],"Ensembl":"ENSG00000156515","Gene description":"Hexokinase 1","Uniprot":["P19367"],"Chromosome":"10","Position":"69269984-69401884","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Allosteric enzyme","Kinase","Transferase"],"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Disease variant","Mental retardation","Neurodegeneration","Neuropathy","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"374.0","Horizontal cells":"304.5","Late spermatids":"1034.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007043","HPA007044","CAB010052"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"560000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB010052":"AB_627721","HPA007043":"AB_1850652","HPA007044":"AB_1079049"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.39e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"47.0","Tissue RNA - adrenal gland [nTPM]":"24.4","Tissue RNA - amygdala [nTPM]":"61.0","Tissue RNA - appendix [nTPM]":"45.0","Tissue RNA - basal ganglia [nTPM]":"65.7","Tissue RNA - bone marrow [nTPM]":"60.3","Tissue RNA - breast [nTPM]":"40.6","Tissue RNA - cerebellum [nTPM]":"58.0","Tissue RNA - cerebral cortex [nTPM]":"76.6","Tissue RNA - cervix [nTPM]":"54.7","Tissue RNA - choroid plexus [nTPM]":"64.2","Tissue RNA - colon [nTPM]":"60.1","Tissue RNA - duodenum [nTPM]":"13.1","Tissue RNA - endometrium 1 [nTPM]":"41.3","Tissue RNA - epididymis [nTPM]":"11.2","Tissue RNA - esophagus [nTPM]":"129.9","Tissue RNA - fallopian tube [nTPM]":"37.0","Tissue RNA - gallbladder [nTPM]":"25.7","Tissue RNA - heart muscle [nTPM]":"150.8","Tissue RNA - hippocampal formation [nTPM]":"69.1","Tissue RNA - hypothalamus [nTPM]":"62.7","Tissue RNA - kidney [nTPM]":"49.2","Tissue RNA - liver [nTPM]":"8.5","Tissue RNA - lung [nTPM]":"48.1","Tissue RNA - lymph node [nTPM]":"34.1","Tissue RNA - medulla oblongata [nTPM]":"56.7","Tissue RNA - midbrain [nTPM]":"59.8","Tissue RNA - ovary [nTPM]":"19.9","Tissue RNA - pancreas [nTPM]":"12.3","Tissue RNA - parathyroid gland [nTPM]":"25.0","Tissue RNA - pituitary gland [nTPM]":"44.9","Tissue RNA - placenta [nTPM]":"49.3","Tissue RNA - pons [nTPM]":"71.1","Tissue RNA - prostate [nTPM]":"52.9","Tissue RNA - rectum [nTPM]":"31.9","Tissue RNA - retina [nTPM]":"147.6","Tissue RNA - salivary gland [nTPM]":"67.1","Tissue RNA - seminal vesicle [nTPM]":"53.1","Tissue RNA - skeletal muscle [nTPM]":"193.5","Tissue RNA - skin 1 [nTPM]":"102.6","Tissue RNA - small intestine [nTPM]":"29.2","Tissue RNA - smooth muscle [nTPM]":"49.8","Tissue RNA - spinal cord [nTPM]":"40.0","Tissue RNA - spleen [nTPM]":"40.3","Tissue RNA - stomach 1 [nTPM]":"61.6","Tissue RNA - testis [nTPM]":"77.2","Tissue RNA - thalamus [nTPM]":"53.5","Tissue RNA - thymus [nTPM]":"44.9","Tissue RNA - thyroid gland [nTPM]":"71.0","Tissue RNA - tongue [nTPM]":"146.7","Tissue RNA - tonsil [nTPM]":"47.6","Tissue RNA - urinary bladder [nTPM]":"74.3","Tissue RNA - vagina [nTPM]":"80.9","Tissue RNA - white matter [nTPM]":"54.1","Cell RNA - A-431 [nTPM]":"101.6","Cell RNA - A549 [nTPM]":"56.6","Cell RNA - AF22 [nTPM]":"74.2","Cell RNA - AN3-CA [nTPM]":"71.1","Cell RNA - ASC diff [nTPM]":"81.0","Cell RNA - ASC TERT1 [nTPM]":"60.4","Cell RNA - BEWO [nTPM]":"47.1","Cell RNA - BJ [nTPM]":"98.3","Cell RNA - BJ hTERT+ [nTPM]":"256.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"128.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"138.0","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"11.0","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"75.8","Cell RNA - fHDF\/TERT166 [nTPM]":"165.9","Cell RNA - GAMG [nTPM]":"92.9","Cell RNA - HaCaT [nTPM]":"86.2","Cell RNA - HAP1 [nTPM]":"69.9","Cell RNA - HBEC3-KT [nTPM]":"220.0","Cell RNA - HBF TERT88 [nTPM]":"122.0","Cell RNA - HDLM-2 [nTPM]":"67.5","Cell RNA - HEK 293 [nTPM]":"54.5","Cell RNA - HEL [nTPM]":"250.0","Cell RNA - HeLa [nTPM]":"58.3","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"91.7","Cell RNA - HL-60 [nTPM]":"5.1","Cell RNA - HMC-1 [nTPM]":"181.2","Cell RNA - HSkMC [nTPM]":"91.5","Cell RNA - hTCEpi [nTPM]":"125.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"184.5","Cell RNA - hTERT-HME1 [nTPM]":"407.6","Cell RNA - hTERT-RPE1 [nTPM]":"160.8","Cell RNA - HUVEC TERT2 [nTPM]":"135.4","Cell RNA - JURKAT [nTPM]":"36.8","Cell RNA - K-562 [nTPM]":"424.5","Cell RNA - Karpas-707 [nTPM]":"51.3","Cell RNA - LHCN-M2 [nTPM]":"178.7","Cell RNA - MCF7 [nTPM]":"167.7","Cell RNA - MOLT-4 [nTPM]":"29.7","Cell RNA - NB-4 [nTPM]":"13.1","Cell RNA - NTERA-2 [nTPM]":"113.8","Cell RNA - OE19 [nTPM]":"51.7","Cell RNA - PC-3 [nTPM]":"247.0","Cell RNA - REH [nTPM]":"44.8","Cell RNA - RH-30 [nTPM]":"45.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"88.7","Cell RNA - RT4 [nTPM]":"117.4","Cell RNA - SCLC-21H [nTPM]":"75.7","Cell RNA - SH-SY5Y [nTPM]":"88.7","Cell RNA - SiHa [nTPM]":"112.6","Cell RNA - SK-BR-3 [nTPM]":"215.4","Cell RNA - SK-MEL-30 [nTPM]":"65.2","Cell RNA - SuSa [nTPM]":"104.3","Cell RNA - T-47d [nTPM]":"117.7","Cell RNA - THP-1 [nTPM]":"16.5","Cell RNA - TIME [nTPM]":"140.4","Cell RNA - U-138 MG [nTPM]":"190.5","Cell RNA - U-2 OS [nTPM]":"86.4","Cell RNA - U-2197 [nTPM]":"106.5","Cell RNA - U-251 MG [nTPM]":"139.6","Cell RNA - U-266\/70 [nTPM]":"61.1","Cell RNA - U-266\/84 [nTPM]":"42.8","Cell RNA - U-698 [nTPM]":"17.4","Cell RNA - U-87 MG [nTPM]":"247.3","Cell RNA - U-937 [nTPM]":"130.4","Cell RNA - WM-115 [nTPM]":"56.1","Blood RNA - basophil [nTPM]":"68.7","Blood RNA - classical monocyte [nTPM]":"88.8","Blood RNA - eosinophil [nTPM]":"44.6","Blood RNA - gdT-cell [nTPM]":"41.5","Blood RNA - intermediate monocyte [nTPM]":"125.2","Blood RNA - MAIT T-cell [nTPM]":"69.0","Blood RNA - memory B-cell [nTPM]":"33.5","Blood RNA - memory CD4 T-cell [nTPM]":"47.9","Blood RNA - memory CD8 T-cell [nTPM]":"47.6","Blood RNA - myeloid DC [nTPM]":"81.0","Blood RNA - naive B-cell [nTPM]":"19.9","Blood RNA - naive CD4 T-cell [nTPM]":"41.7","Blood RNA - naive CD8 T-cell [nTPM]":"33.9","Blood RNA - neutrophil [nTPM]":"20.9","Blood RNA - NK-cell [nTPM]":"31.2","Blood RNA - non-classical monocyte [nTPM]":"135.4","Blood RNA - plasmacytoid DC [nTPM]":"9.1","Blood RNA - T-reg [nTPM]":"58.1","Blood RNA - total PBMC [nTPM]":"110.4","Brain RNA - amygdala [nTPM]":"61.0","Brain RNA - basal ganglia [nTPM]":"65.7","Brain RNA - cerebellum [nTPM]":"58.0","Brain RNA - cerebral cortex [nTPM]":"76.6","Brain RNA - hippocampal formation [nTPM]":"69.1","Brain RNA - hypothalamus [nTPM]":"62.7","Brain RNA - medulla oblongata [nTPM]":"56.7","Brain RNA - midbrain [nTPM]":"59.8","Brain RNA - pons [nTPM]":"71.1","Brain RNA - spinal cord [nTPM]":"40.0","Brain RNA - thalamus [nTPM]":"53.5","Brain RNA - white matter [nTPM]":"54.1","Single Cell Type RNA - Adipocytes [nTPM]":"26.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.4","Single Cell Type RNA - Astrocytes [nTPM]":"38.2","Single Cell Type RNA - B-cells [nTPM]":"26.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"48.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"50.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"83.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"130.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"34.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"70.6","Single Cell Type RNA - dendritic cells [nTPM]":"14.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"28.6","Single Cell Type RNA - Early spermatids [nTPM]":"374.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.0","Single Cell Type RNA - Endothelial cells [nTPM]":"37.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.7","Single Cell Type RNA - Erythroid cells [nTPM]":"104.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"93.3","Single Cell Type RNA - Fibroblasts [nTPM]":"30.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.5","Single Cell Type RNA - granulocytes [nTPM]":"23.4","Single Cell Type RNA - Granulosa cells [nTPM]":"72.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.4","Single Cell Type RNA - Horizontal cells [nTPM]":"304.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"49.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.7","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"41.7","Single Cell Type RNA - Langerhans cells [nTPM]":"21.9","Single Cell Type RNA - Late spermatids [nTPM]":"1034.1","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"51.3","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"35.3","Single Cell Type RNA - Muller glia cells [nTPM]":"32.9","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.6","Single Cell Type RNA - Paneth cells [nTPM]":"11.1","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"19.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"95.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.1","Single Cell Type RNA - Spermatocytes [nTPM]":"5.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"86.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"51.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"118.9","Single Cell Type RNA - T-cells [nTPM]":"30.5","Single Cell Type RNA - Theca cells [nTPM]":"28.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.3","Single Cell Type RNA - Urothelial cells [nTPM]":"43.5"},{"Gene":"HLA-DQB1","Gene synonym":["CELIAC1","HLA-DQB","IDDM1"],"Ensembl":"ENSG00000179344","Gene description":"Major histocompatibility complex, class II, DQ beta 1","Uniprot":[],"Chromosome":"6","Position":"32659467-32668383","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"179.1","lymphoid tissue":"301.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"995.1","Langerhans cells":"4144.8","Macrophages":"1090.5","monocytes":"1038.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"153.5","intermediate monocyte":"142.9","memory B-cell":"159.2","myeloid DC":"386.3","naive B-cell":"169.1","plasmacytoid DC":"116.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"169.1","dendritic cells":"386.3","monocytes":"153.5"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"HDLM-2":"599.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013667"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Rods & Rings"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA013667":"AB_1853932"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"56.6","Tissue RNA - adrenal gland [nTPM]":"23.9","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"77.8","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"40.0","Tissue RNA - breast [nTPM]":"45.3","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"45.8","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"18.9","Tissue RNA - epididymis [nTPM]":"126.9","Tissue RNA - esophagus [nTPM]":"21.3","Tissue RNA - fallopian tube [nTPM]":"22.2","Tissue RNA - gallbladder [nTPM]":"43.6","Tissue RNA - heart muscle [nTPM]":"21.6","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"34.3","Tissue RNA - liver [nTPM]":"37.1","Tissue RNA - lung [nTPM]":"179.1","Tissue RNA - lymph node [nTPM]":"301.8","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"3.8","Tissue RNA - ovary [nTPM]":"7.4","Tissue RNA - pancreas [nTPM]":"14.3","Tissue RNA - parathyroid gland [nTPM]":"10.6","Tissue RNA - pituitary gland [nTPM]":"21.3","Tissue RNA - placenta [nTPM]":"10.1","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"17.1","Tissue RNA - rectum [nTPM]":"39.0","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"24.2","Tissue RNA - seminal vesicle [nTPM]":"11.9","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"31.8","Tissue RNA - small intestine [nTPM]":"78.0","Tissue RNA - smooth muscle [nTPM]":"11.2","Tissue RNA - spinal cord [nTPM]":"4.6","Tissue RNA - spleen [nTPM]":"139.3","Tissue RNA - stomach 1 [nTPM]":"128.0","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"108.2","Tissue RNA - thyroid gland [nTPM]":"26.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"122.3","Tissue RNA - urinary bladder [nTPM]":"89.9","Tissue RNA - vagina [nTPM]":"16.9","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"93.9","Cell RNA - EFO-21 [nTPM]":"2.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"19.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"19.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"599.9","Cell RNA - HEK 293 [nTPM]":"13.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"3.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"7.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"3.3","Cell RNA - THP-1 [nTPM]":"10.9","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"68.7","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"66.0","Cell RNA - U-87 MG [nTPM]":"47.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"153.5","Blood RNA - eosinophil [nTPM]":"27.9","Blood RNA - gdT-cell [nTPM]":"12.8","Blood RNA - intermediate monocyte [nTPM]":"142.9","Blood RNA - MAIT T-cell [nTPM]":"6.6","Blood RNA - memory B-cell [nTPM]":"159.2","Blood RNA - memory CD4 T-cell [nTPM]":"6.9","Blood RNA - memory CD8 T-cell [nTPM]":"20.0","Blood RNA - myeloid DC [nTPM]":"386.3","Blood RNA - naive B-cell [nTPM]":"169.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"6.3","Blood RNA - neutrophil [nTPM]":"11.8","Blood RNA - NK-cell [nTPM]":"10.4","Blood RNA - non-classical monocyte [nTPM]":"41.1","Blood RNA - plasmacytoid DC [nTPM]":"116.5","Blood RNA - T-reg [nTPM]":"41.1","Blood RNA - total PBMC [nTPM]":"217.0","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"3.8","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"4.6","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"162.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"181.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"995.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"40.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"188.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"38.8","Single Cell Type RNA - Early spermatids [nTPM]":"16.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"135.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.8","Single Cell Type RNA - Erythroid cells [nTPM]":"37.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"18.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"38.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"422.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"487.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4144.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"1090.5","Single Cell Type RNA - Melanocytes [nTPM]":"97.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"1038.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.3","Single Cell Type RNA - Paneth cells [nTPM]":"27.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"86.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"417.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"66.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - T-cells [nTPM]":"84.5","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.1","Single Cell Type RNA - Urothelial cells [nTPM]":"49.1"},{"Gene":"HLA-DRB1","Gene synonym":["HLA-DR1B"],"Ensembl":"ENSG00000196126","Gene description":"Major histocompatibility complex, class II, DR beta 1","Uniprot":["P01911"],"Chromosome":"6","Position":"32578769-32589848","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"581.3","lymphoid tissue":"651.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"2149.9","Langerhans cells":"11630.1","Macrophages":"3622.3","monocytes":"3104.1","Proximal enterocytes":"1849.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"47.5"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"749.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"257.9","dendritic cells":"749.2","monocytes":"371.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"1181.9","HMC-1":"159.7","THP-1":"140.4","U-266\/70":"150.3","U-698":"202.5","U-87 MG":"308.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015400","CAB034021","HPA043151"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015400":"AB_784538","CAB034021":"AB_1124844","HPA043151":"AB_2678342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"311.4","Tissue RNA - adrenal gland [nTPM]":"162.1","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"220.8","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"61.3","Tissue RNA - breast [nTPM]":"239.4","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"47.5","Tissue RNA - cervix [nTPM]":"121.4","Tissue RNA - choroid plexus [nTPM]":"11.1","Tissue RNA - colon [nTPM]":"113.5","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"90.3","Tissue RNA - epididymis [nTPM]":"140.6","Tissue RNA - esophagus [nTPM]":"71.7","Tissue RNA - fallopian tube [nTPM]":"119.4","Tissue RNA - gallbladder [nTPM]":"66.9","Tissue RNA - heart muscle [nTPM]":"134.6","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"217.5","Tissue RNA - liver [nTPM]":"100.6","Tissue RNA - lung [nTPM]":"581.3","Tissue RNA - lymph node [nTPM]":"651.4","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"40.4","Tissue RNA - pancreas [nTPM]":"50.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"80.2","Tissue RNA - placenta [nTPM]":"13.6","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"88.4","Tissue RNA - rectum [nTPM]":"135.3","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"93.8","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"58.3","Tissue RNA - skin 1 [nTPM]":"122.5","Tissue RNA - small intestine [nTPM]":"353.2","Tissue RNA - smooth muscle [nTPM]":"11.1","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"516.2","Tissue RNA - stomach 1 [nTPM]":"232.3","Tissue RNA - testis [nTPM]":"25.5","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"254.3","Tissue RNA - thyroid gland [nTPM]":"129.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"257.4","Tissue RNA - urinary bladder [nTPM]":"116.2","Tissue RNA - vagina [nTPM]":"91.5","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"2.4","Cell RNA - EFO-21 [nTPM]":"17.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"4.7","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1181.9","Cell RNA - HEK 293 [nTPM]":"12.9","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"159.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"12.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"28.5","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"2.3","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"4.4","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"6.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"26.7","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"140.4","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"150.3","Cell RNA - U-266\/84 [nTPM]":"4.4","Cell RNA - U-698 [nTPM]":"202.5","Cell RNA - U-87 MG [nTPM]":"308.9","Cell RNA - U-937 [nTPM]":"5.8","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"323.0","Blood RNA - eosinophil [nTPM]":"53.7","Blood RNA - gdT-cell [nTPM]":"12.2","Blood RNA - intermediate monocyte [nTPM]":"371.3","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"225.4","Blood RNA - memory CD4 T-cell [nTPM]":"9.0","Blood RNA - memory CD8 T-cell [nTPM]":"27.2","Blood RNA - myeloid DC [nTPM]":"749.2","Blood RNA - naive B-cell [nTPM]":"257.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"12.2","Blood RNA - neutrophil [nTPM]":"8.9","Blood RNA - NK-cell [nTPM]":"21.0","Blood RNA - non-classical monocyte [nTPM]":"223.8","Blood RNA - plasmacytoid DC [nTPM]":"147.6","Blood RNA - T-reg [nTPM]":"35.4","Blood RNA - total PBMC [nTPM]":"411.8","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"47.5","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"1241.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"147.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"609.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2149.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"173.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"78.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"96.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"150.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"90.1","Single Cell Type RNA - Club cells [nTPM]":"277.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"141.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"484.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"92.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"272.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.0","Single Cell Type RNA - Endothelial cells [nTPM]":"721.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.0","Single Cell Type RNA - Erythroid cells [nTPM]":"120.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"73.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.0","Single Cell Type RNA - Fibroblasts [nTPM]":"77.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"131.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.6","Single Cell Type RNA - granulocytes [nTPM]":"124.0","Single Cell Type RNA - Granulosa cells [nTPM]":"47.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"179.9","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1417.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"92.7","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"1755.3","Single Cell Type RNA - Langerhans cells [nTPM]":"11630.1","Single Cell Type RNA - Late spermatids [nTPM]":"12.3","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"3622.3","Single Cell Type RNA - Melanocytes [nTPM]":"217.1","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"3104.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"89.1","Single Cell Type RNA - Paneth cells [nTPM]":"308.9","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"120.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1849.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"218.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"357.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"147.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - T-cells [nTPM]":"245.6","Single Cell Type RNA - Theca cells [nTPM]":"52.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"152.2","Single Cell Type RNA - Urothelial cells [nTPM]":"125.5"},{"Gene":"HMCN1","Gene synonym":["ARMD1","FBLN6","FIBL-6","FIBL6"],"Ensembl":"ENSG00000143341","Gene description":"Hemicentin 1","Uniprot":["Q96RW7"],"Chromosome":"1","Position":"185734391-186190949","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell cycle","Cell division","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Age-related macular degeneration","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"20.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"33.8","Endothelial cells":"21.4","Fibroblasts":"22.2","Horizontal cells":"26.9","Microglial cells":"45.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"melanoma":"14.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"22.3","hTERT-RPE1":"20.1","MCF7":"76.5","SK-MEL-30":"50.2","WM-115":"43.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"olfactory bulb":"9.9"},"Antibody":["HPA008220","HPA051677"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9200000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008220":null,"HPA051677":"AB_2681572"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"8.4","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"9.0","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"20.3","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"3.9","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"7.5","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"4.8","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"3.1","Tissue RNA - smooth muscle [nTPM]":"4.3","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"8.4","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"7.0","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"1.8","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"1.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"4.7","Cell RNA - ASC TERT1 [nTPM]":"4.7","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"1.9","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"22.3","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"5.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.6","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"20.1","Cell RNA - HUVEC TERT2 [nTPM]":"2.8","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"76.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"3.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"50.2","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"13.7","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"5.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"2.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"43.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"33.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"21.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"22.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"HNRNPA1","Gene synonym":["ALS20","hnRNP-A1","HNRPA1"],"Ensembl":"ENSG00000135486","Gene description":"Heterogeneous nuclear ribonucleoprotein A1","Uniprot":["P09651"],"Chromosome":"12","Position":"54280193-54287088","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","mRNA processing","mRNA splicing","mRNA transport","Transport"],"Molecular function":["Ribonucleoprotein","RNA-binding"],"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001609","HPA001666","HPA005812","HPA007185","CAB010894"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9300000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB010894":"AB_261962","HPA001609":"AB_2666383","HPA001666":"AB_1850836","HPA005812":"AB_2667441","HPA007185":"AB_2667768"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-3"},"Tissue RNA - adipose tissue [nTPM]":"531.6","Tissue RNA - adrenal gland [nTPM]":"410.2","Tissue RNA - amygdala [nTPM]":"339.5","Tissue RNA - appendix [nTPM]":"528.1","Tissue RNA - basal ganglia [nTPM]":"362.6","Tissue RNA - bone marrow [nTPM]":"1087.9","Tissue RNA - breast [nTPM]":"640.6","Tissue RNA - cerebellum [nTPM]":"348.2","Tissue RNA - cerebral cortex [nTPM]":"424.9","Tissue RNA - cervix [nTPM]":"750.3","Tissue RNA - choroid plexus [nTPM]":"326.5","Tissue RNA - colon [nTPM]":"542.3","Tissue RNA - duodenum [nTPM]":"447.5","Tissue RNA - endometrium 1 [nTPM]":"625.3","Tissue RNA - epididymis [nTPM]":"474.8","Tissue RNA - esophagus [nTPM]":"510.3","Tissue RNA - fallopian tube [nTPM]":"589.2","Tissue RNA - gallbladder [nTPM]":"214.7","Tissue RNA - heart muscle [nTPM]":"391.4","Tissue RNA - hippocampal formation [nTPM]":"320.7","Tissue RNA - hypothalamus [nTPM]":"363.0","Tissue RNA - kidney [nTPM]":"501.4","Tissue RNA - liver [nTPM]":"277.0","Tissue RNA - lung [nTPM]":"380.6","Tissue RNA - lymph node [nTPM]":"685.7","Tissue RNA - medulla oblongata [nTPM]":"363.3","Tissue RNA - midbrain [nTPM]":"348.2","Tissue RNA - ovary [nTPM]":"1410.2","Tissue RNA - pancreas [nTPM]":"556.7","Tissue RNA - parathyroid gland [nTPM]":"359.8","Tissue RNA - pituitary gland [nTPM]":"327.2","Tissue RNA - placenta [nTPM]":"447.9","Tissue RNA - pons [nTPM]":"364.8","Tissue RNA - prostate [nTPM]":"458.9","Tissue RNA - rectum [nTPM]":"445.9","Tissue RNA - retina [nTPM]":"261.2","Tissue RNA - salivary gland [nTPM]":"398.9","Tissue RNA - seminal vesicle [nTPM]":"409.6","Tissue RNA - skeletal muscle [nTPM]":"437.4","Tissue RNA - skin 1 [nTPM]":"506.3","Tissue RNA - small intestine [nTPM]":"436.4","Tissue RNA - smooth muscle [nTPM]":"382.1","Tissue RNA - spinal cord [nTPM]":"380.9","Tissue RNA - spleen [nTPM]":"434.1","Tissue RNA - stomach 1 [nTPM]":"431.0","Tissue RNA - testis [nTPM]":"168.9","Tissue RNA - thalamus [nTPM]":"343.9","Tissue RNA - thymus [nTPM]":"1010.9","Tissue RNA - thyroid gland [nTPM]":"396.3","Tissue RNA - tongue [nTPM]":"174.4","Tissue RNA - tonsil [nTPM]":"824.8","Tissue RNA - urinary bladder [nTPM]":"513.7","Tissue RNA - vagina [nTPM]":"580.9","Tissue RNA - white matter [nTPM]":"372.6","Cell RNA - A-431 [nTPM]":"1246.7","Cell RNA - A549 [nTPM]":"815.8","Cell RNA - AF22 [nTPM]":"2072.5","Cell RNA - AN3-CA [nTPM]":"1717.3","Cell RNA - ASC diff [nTPM]":"550.5","Cell RNA - ASC TERT1 [nTPM]":"1057.0","Cell RNA - BEWO [nTPM]":"1204.0","Cell RNA - BJ [nTPM]":"911.9","Cell RNA - BJ hTERT+ [nTPM]":"1405.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1311.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1153.1","Cell RNA - CACO-2 [nTPM]":"1225.4","Cell RNA - CAPAN-2 [nTPM]":"1306.6","Cell RNA - Daudi [nTPM]":"3183.8","Cell RNA - EFO-21 [nTPM]":"983.8","Cell RNA - fHDF\/TERT166 [nTPM]":"671.8","Cell RNA - GAMG [nTPM]":"354.7","Cell RNA - HaCaT [nTPM]":"1045.9","Cell RNA - HAP1 [nTPM]":"1486.5","Cell RNA - HBEC3-KT [nTPM]":"1393.4","Cell RNA - HBF TERT88 [nTPM]":"1425.5","Cell RNA - HDLM-2 [nTPM]":"1216.4","Cell RNA - HEK 293 [nTPM]":"1041.7","Cell RNA - HEL [nTPM]":"1700.0","Cell RNA - HeLa [nTPM]":"1156.1","Cell RNA - Hep G2 [nTPM]":"2250.0","Cell RNA - HHSteC [nTPM]":"320.4","Cell RNA - HL-60 [nTPM]":"2712.4","Cell RNA - HMC-1 [nTPM]":"1078.2","Cell RNA - HSkMC [nTPM]":"845.2","Cell RNA - hTCEpi [nTPM]":"568.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"642.9","Cell RNA - hTERT-HME1 [nTPM]":"1056.1","Cell RNA - hTERT-RPE1 [nTPM]":"868.7","Cell RNA - HUVEC TERT2 [nTPM]":"1408.6","Cell RNA - JURKAT [nTPM]":"1474.7","Cell RNA - K-562 [nTPM]":"1930.7","Cell RNA - Karpas-707 [nTPM]":"1215.3","Cell RNA - LHCN-M2 [nTPM]":"968.2","Cell RNA - MCF7 [nTPM]":"1244.6","Cell RNA - MOLT-4 [nTPM]":"2969.1","Cell RNA - NB-4 [nTPM]":"2880.9","Cell RNA - NTERA-2 [nTPM]":"2571.8","Cell RNA - OE19 [nTPM]":"844.0","Cell RNA - PC-3 [nTPM]":"675.9","Cell RNA - REH [nTPM]":"2911.7","Cell RNA - RH-30 [nTPM]":"1588.9","Cell RNA - RPMI-8226 [nTPM]":"1574.1","Cell RNA - RPTEC TERT1 [nTPM]":"1239.4","Cell RNA - RT4 [nTPM]":"1395.0","Cell RNA - SCLC-21H [nTPM]":"1260.4","Cell RNA - SH-SY5Y [nTPM]":"1739.0","Cell RNA - SiHa [nTPM]":"758.0","Cell RNA - SK-BR-3 [nTPM]":"1675.2","Cell RNA - SK-MEL-30 [nTPM]":"1392.3","Cell RNA - SuSa [nTPM]":"1031.6","Cell RNA - T-47d [nTPM]":"1010.9","Cell RNA - THP-1 [nTPM]":"1744.5","Cell RNA - TIME [nTPM]":"1063.1","Cell RNA - U-138 MG [nTPM]":"781.6","Cell RNA - U-2 OS [nTPM]":"1164.2","Cell RNA - U-2197 [nTPM]":"820.6","Cell RNA - U-251 MG [nTPM]":"1395.1","Cell RNA - U-266\/70 [nTPM]":"1185.7","Cell RNA - U-266\/84 [nTPM]":"1349.3","Cell RNA - U-698 [nTPM]":"2249.7","Cell RNA - U-87 MG [nTPM]":"572.5","Cell RNA - U-937 [nTPM]":"1646.7","Cell RNA - WM-115 [nTPM]":"744.0","Blood RNA - basophil [nTPM]":"140.4","Blood RNA - classical monocyte [nTPM]":"423.5","Blood RNA - eosinophil [nTPM]":"165.9","Blood RNA - gdT-cell [nTPM]":"572.8","Blood RNA - intermediate monocyte [nTPM]":"513.1","Blood RNA - MAIT T-cell [nTPM]":"893.3","Blood RNA - memory B-cell [nTPM]":"576.5","Blood RNA - memory CD4 T-cell [nTPM]":"746.2","Blood RNA - memory CD8 T-cell [nTPM]":"657.5","Blood RNA - myeloid DC [nTPM]":"704.5","Blood RNA - naive B-cell [nTPM]":"501.8","Blood RNA - naive CD4 T-cell [nTPM]":"851.2","Blood RNA - naive CD8 T-cell [nTPM]":"810.1","Blood RNA - neutrophil [nTPM]":"41.0","Blood RNA - NK-cell [nTPM]":"823.3","Blood RNA - non-classical monocyte [nTPM]":"437.7","Blood RNA - plasmacytoid DC [nTPM]":"556.5","Blood RNA - T-reg [nTPM]":"683.4","Blood RNA - total PBMC [nTPM]":"1333.2","Brain RNA - amygdala [nTPM]":"339.5","Brain RNA - basal ganglia [nTPM]":"362.6","Brain RNA - cerebellum [nTPM]":"348.2","Brain RNA - cerebral cortex [nTPM]":"424.9","Brain RNA - hippocampal formation [nTPM]":"320.7","Brain RNA - hypothalamus [nTPM]":"363.0","Brain RNA - medulla oblongata [nTPM]":"363.3","Brain RNA - midbrain [nTPM]":"348.2","Brain RNA - pons [nTPM]":"364.8","Brain RNA - spinal cord [nTPM]":"380.9","Brain RNA - thalamus [nTPM]":"343.9","Brain RNA - white matter [nTPM]":"372.6","Single Cell Type RNA - Adipocytes [nTPM]":"372.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"304.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"521.4","Single Cell Type RNA - Astrocytes [nTPM]":"20.9","Single Cell Type RNA - B-cells [nTPM]":"1018.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1416.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1039.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1252.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"900.9","Single Cell Type RNA - Bipolar cells [nTPM]":"254.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"745.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"541.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"166.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"697.7","Single Cell Type RNA - Club cells [nTPM]":"612.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"294.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"93.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2076.2","Single Cell Type RNA - dendritic cells [nTPM]":"900.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"407.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"739.6","Single Cell Type RNA - Ductal cells [nTPM]":"1296.2","Single Cell Type RNA - Early spermatids [nTPM]":"181.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"304.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"706.7","Single Cell Type RNA - Endothelial cells [nTPM]":"624.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"824.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1032.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2124.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2894.5","Single Cell Type RNA - Fibroblasts [nTPM]":"600.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"458.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"400.7","Single Cell Type RNA - granulocytes [nTPM]":"528.9","Single Cell Type RNA - Granulosa cells [nTPM]":"790.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"562.2","Single Cell Type RNA - Hepatocytes [nTPM]":"183.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1006.9","Single Cell Type RNA - Horizontal cells [nTPM]":"109.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1130.9","Single Cell Type RNA - Ionocytes [nTPM]":"459.8","Single Cell Type RNA - Kupffer cells [nTPM]":"863.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1048.2","Single Cell Type RNA - Late spermatids [nTPM]":"115.6","Single Cell Type RNA - Leydig cells [nTPM]":"1050.7","Single Cell Type RNA - Macrophages [nTPM]":"609.2","Single Cell Type RNA - Melanocytes [nTPM]":"588.7","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"1374.4","Single Cell Type RNA - Muller glia cells [nTPM]":"411.0","Single Cell Type RNA - NK-cells [nTPM]":"1304.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1162.7","Single Cell Type RNA - Paneth cells [nTPM]":"731.2","Single Cell Type RNA - Peritubular cells [nTPM]":"741.8","Single Cell Type RNA - Plasma cells [nTPM]":"702.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"696.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"693.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"838.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"288.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"195.2","Single Cell Type RNA - Sertoli cells [nTPM]":"453.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"714.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"704.1","Single Cell Type RNA - Spermatocytes [nTPM]":"217.0","Single Cell Type RNA - Spermatogonia [nTPM]":"338.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1030.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1261.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2178.8","Single Cell Type RNA - T-cells [nTPM]":"958.6","Single Cell Type RNA - Theca cells [nTPM]":"690.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1543.8","Single Cell Type RNA - Urothelial cells [nTPM]":"897.8"},{"Gene":"HNRNPU","Gene synonym":["C1orf199","FLJ30202","FLJ37978","HNRNPU-AS1","HNRPU","NCRNA00201","SAF-A"],"Ensembl":"ENSG00000153187","Gene description":"Heterogeneous nuclear ribonucleoprotein U","Uniprot":["Q00839"],"Chromosome":"1","Position":"244840638-244864560","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Cell cycle","Cell division","Differentiation","Host-virus interaction","Mitosis","mRNA processing","mRNA splicing","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Developmental protein","DNA-binding","Repressor","Ribonucleoprotein","RNA-binding"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011532","HPA041057","HPA058707"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB011532":"AB_732983","HPA041057":"AB_2677278","HPA058707":"AB_2683796"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.88e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"110.3","Tissue RNA - adrenal gland [nTPM]":"111.9","Tissue RNA - amygdala [nTPM]":"123.7","Tissue RNA - appendix [nTPM]":"76.1","Tissue RNA - basal ganglia [nTPM]":"132.5","Tissue RNA - bone marrow [nTPM]":"177.5","Tissue RNA - breast [nTPM]":"100.9","Tissue RNA - cerebellum [nTPM]":"131.8","Tissue RNA - cerebral cortex [nTPM]":"139.8","Tissue RNA - cervix [nTPM]":"101.6","Tissue RNA - choroid plexus [nTPM]":"122.3","Tissue RNA - colon [nTPM]":"93.3","Tissue RNA - duodenum [nTPM]":"65.5","Tissue RNA - endometrium 1 [nTPM]":"103.0","Tissue RNA - epididymis [nTPM]":"121.3","Tissue RNA - esophagus [nTPM]":"99.9","Tissue RNA - fallopian tube [nTPM]":"106.6","Tissue RNA - gallbladder [nTPM]":"62.7","Tissue RNA - heart muscle [nTPM]":"92.7","Tissue RNA - hippocampal formation [nTPM]":"122.5","Tissue RNA - hypothalamus [nTPM]":"123.5","Tissue RNA - kidney [nTPM]":"129.9","Tissue RNA - liver [nTPM]":"105.6","Tissue RNA - lung [nTPM]":"80.7","Tissue RNA - lymph node [nTPM]":"98.3","Tissue RNA - medulla oblongata [nTPM]":"125.7","Tissue RNA - midbrain [nTPM]":"127.9","Tissue RNA - ovary [nTPM]":"134.5","Tissue RNA - pancreas [nTPM]":"99.4","Tissue RNA - parathyroid gland [nTPM]":"109.6","Tissue RNA - pituitary gland [nTPM]":"88.2","Tissue RNA - placenta [nTPM]":"96.0","Tissue RNA - pons [nTPM]":"127.3","Tissue RNA - prostate [nTPM]":"92.2","Tissue RNA - rectum [nTPM]":"84.2","Tissue RNA - retina [nTPM]":"126.3","Tissue RNA - salivary gland [nTPM]":"86.8","Tissue RNA - seminal vesicle [nTPM]":"79.5","Tissue RNA - skeletal muscle [nTPM]":"116.5","Tissue RNA - skin 1 [nTPM]":"91.9","Tissue RNA - small intestine [nTPM]":"94.5","Tissue RNA - smooth muscle [nTPM]":"76.7","Tissue RNA - spinal cord [nTPM]":"129.8","Tissue RNA - spleen [nTPM]":"103.0","Tissue RNA - stomach 1 [nTPM]":"95.0","Tissue RNA - testis [nTPM]":"90.2","Tissue RNA - thalamus [nTPM]":"127.6","Tissue RNA - thymus [nTPM]":"141.2","Tissue RNA - thyroid gland [nTPM]":"103.6","Tissue RNA - tongue [nTPM]":"61.6","Tissue RNA - tonsil [nTPM]":"115.5","Tissue RNA - urinary bladder [nTPM]":"97.0","Tissue RNA - vagina [nTPM]":"86.8","Tissue RNA - white matter [nTPM]":"144.6","Cell RNA - A-431 [nTPM]":"308.9","Cell RNA - A549 [nTPM]":"242.9","Cell RNA - AF22 [nTPM]":"311.8","Cell RNA - AN3-CA [nTPM]":"249.4","Cell RNA - ASC diff [nTPM]":"160.5","Cell RNA - ASC TERT1 [nTPM]":"136.4","Cell RNA - BEWO [nTPM]":"307.9","Cell RNA - BJ [nTPM]":"215.2","Cell RNA - BJ hTERT+ [nTPM]":"138.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"193.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"171.1","Cell RNA - CACO-2 [nTPM]":"234.0","Cell RNA - CAPAN-2 [nTPM]":"198.6","Cell RNA - Daudi [nTPM]":"481.9","Cell RNA - EFO-21 [nTPM]":"195.6","Cell RNA - fHDF\/TERT166 [nTPM]":"183.0","Cell RNA - GAMG [nTPM]":"185.4","Cell RNA - HaCaT [nTPM]":"235.3","Cell RNA - HAP1 [nTPM]":"424.4","Cell RNA - HBEC3-KT [nTPM]":"244.0","Cell RNA - HBF TERT88 [nTPM]":"304.5","Cell RNA - HDLM-2 [nTPM]":"204.8","Cell RNA - HEK 293 [nTPM]":"280.2","Cell RNA - HEL [nTPM]":"417.4","Cell RNA - HeLa [nTPM]":"203.4","Cell RNA - Hep G2 [nTPM]":"360.7","Cell RNA - HHSteC [nTPM]":"168.8","Cell RNA - HL-60 [nTPM]":"482.7","Cell RNA - HMC-1 [nTPM]":"242.9","Cell RNA - HSkMC [nTPM]":"156.2","Cell RNA - hTCEpi [nTPM]":"143.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"211.6","Cell RNA - hTERT-HME1 [nTPM]":"220.1","Cell RNA - hTERT-RPE1 [nTPM]":"169.8","Cell RNA - HUVEC TERT2 [nTPM]":"200.4","Cell RNA - JURKAT [nTPM]":"296.9","Cell RNA - K-562 [nTPM]":"553.0","Cell RNA - Karpas-707 [nTPM]":"174.0","Cell RNA - LHCN-M2 [nTPM]":"264.3","Cell RNA - MCF7 [nTPM]":"221.2","Cell RNA - MOLT-4 [nTPM]":"517.8","Cell RNA - NB-4 [nTPM]":"497.8","Cell RNA - NTERA-2 [nTPM]":"545.5","Cell RNA - OE19 [nTPM]":"227.4","Cell RNA - PC-3 [nTPM]":"217.2","Cell RNA - REH [nTPM]":"510.6","Cell RNA - RH-30 [nTPM]":"392.7","Cell RNA - RPMI-8226 [nTPM]":"261.9","Cell RNA - RPTEC TERT1 [nTPM]":"314.3","Cell RNA - RT4 [nTPM]":"222.9","Cell RNA - SCLC-21H [nTPM]":"260.6","Cell RNA - SH-SY5Y [nTPM]":"257.5","Cell RNA - SiHa [nTPM]":"339.2","Cell RNA - SK-BR-3 [nTPM]":"220.4","Cell RNA - SK-MEL-30 [nTPM]":"280.9","Cell RNA - SuSa [nTPM]":"226.8","Cell RNA - T-47d [nTPM]":"305.2","Cell RNA - THP-1 [nTPM]":"531.7","Cell RNA - TIME [nTPM]":"244.5","Cell RNA - U-138 MG [nTPM]":"192.6","Cell RNA - U-2 OS [nTPM]":"283.7","Cell RNA - U-2197 [nTPM]":"207.0","Cell RNA - U-251 MG [nTPM]":"384.3","Cell RNA - U-266\/70 [nTPM]":"283.4","Cell RNA - U-266\/84 [nTPM]":"332.9","Cell RNA - U-698 [nTPM]":"458.6","Cell RNA - U-87 MG [nTPM]":"156.8","Cell RNA - U-937 [nTPM]":"403.1","Cell RNA - WM-115 [nTPM]":"282.2","Blood RNA - basophil [nTPM]":"23.0","Blood RNA - classical monocyte [nTPM]":"14.4","Blood RNA - eosinophil [nTPM]":"20.6","Blood RNA - gdT-cell [nTPM]":"18.0","Blood RNA - intermediate monocyte [nTPM]":"12.9","Blood RNA - MAIT T-cell [nTPM]":"19.2","Blood RNA - memory B-cell [nTPM]":"22.6","Blood RNA - memory CD4 T-cell [nTPM]":"22.0","Blood RNA - memory CD8 T-cell [nTPM]":"22.1","Blood RNA - myeloid DC [nTPM]":"15.8","Blood RNA - naive B-cell [nTPM]":"21.8","Blood RNA - naive CD4 T-cell [nTPM]":"25.5","Blood RNA - naive CD8 T-cell [nTPM]":"21.5","Blood RNA - neutrophil [nTPM]":"20.6","Blood RNA - NK-cell [nTPM]":"19.8","Blood RNA - non-classical monocyte [nTPM]":"15.0","Blood RNA - plasmacytoid DC [nTPM]":"31.3","Blood RNA - T-reg [nTPM]":"21.3","Blood RNA - total PBMC [nTPM]":"10.1","Brain RNA - amygdala [nTPM]":"123.7","Brain RNA - basal ganglia [nTPM]":"132.5","Brain RNA - cerebellum [nTPM]":"131.8","Brain RNA - cerebral cortex [nTPM]":"139.8","Brain RNA - hippocampal formation [nTPM]":"122.5","Brain RNA - hypothalamus [nTPM]":"123.5","Brain RNA - medulla oblongata [nTPM]":"125.7","Brain RNA - midbrain [nTPM]":"127.9","Brain RNA - pons [nTPM]":"127.3","Brain RNA - spinal cord [nTPM]":"129.8","Brain RNA - thalamus [nTPM]":"127.6","Brain RNA - white matter [nTPM]":"144.6","Single Cell Type RNA - Adipocytes [nTPM]":"269.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"326.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"375.8","Single Cell Type RNA - Astrocytes [nTPM]":"67.9","Single Cell Type RNA - B-cells [nTPM]":"271.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"271.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"416.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"137.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"277.2","Single Cell Type RNA - Bipolar cells [nTPM]":"149.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"254.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"166.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"186.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"118.7","Single Cell Type RNA - Club cells [nTPM]":"281.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"193.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"183.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"202.2","Single Cell Type RNA - dendritic cells [nTPM]":"323.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"163.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"97.8","Single Cell Type RNA - Ductal cells [nTPM]":"215.5","Single Cell Type RNA - Early spermatids [nTPM]":"389.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"283.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"530.1","Single Cell Type RNA - Endothelial cells [nTPM]":"248.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"198.1","Single Cell Type RNA - Erythroid cells [nTPM]":"269.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"180.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"259.5","Single Cell Type RNA - Fibroblasts [nTPM]":"267.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"202.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"429.8","Single Cell Type RNA - granulocytes [nTPM]":"363.6","Single Cell Type RNA - Granulosa cells [nTPM]":"375.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"133.2","Single Cell Type RNA - Hepatocytes [nTPM]":"121.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"184.5","Single Cell Type RNA - Horizontal cells [nTPM]":"141.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"65.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"208.0","Single Cell Type RNA - Ionocytes [nTPM]":"109.9","Single Cell Type RNA - Kupffer cells [nTPM]":"223.7","Single Cell Type RNA - Langerhans cells [nTPM]":"268.6","Single Cell Type RNA - Late spermatids [nTPM]":"481.9","Single Cell Type RNA - Leydig cells [nTPM]":"153.7","Single Cell Type RNA - Macrophages [nTPM]":"402.7","Single Cell Type RNA - Melanocytes [nTPM]":"122.7","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"251.4","Single Cell Type RNA - Muller glia cells [nTPM]":"151.4","Single Cell Type RNA - NK-cells [nTPM]":"228.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"67.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"107.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"188.9","Single Cell Type RNA - Paneth cells [nTPM]":"141.8","Single Cell Type RNA - Peritubular cells [nTPM]":"142.6","Single Cell Type RNA - Plasma cells [nTPM]":"331.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"215.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"141.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"133.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"240.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"213.7","Single Cell Type RNA - Sertoli cells [nTPM]":"144.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"317.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"364.3","Single Cell Type RNA - Spermatocytes [nTPM]":"194.9","Single Cell Type RNA - Spermatogonia [nTPM]":"162.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"292.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"239.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"252.7","Single Cell Type RNA - T-cells [nTPM]":"310.6","Single Cell Type RNA - Theca cells [nTPM]":"379.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"234.6","Single Cell Type RNA - Urothelial cells [nTPM]":"288.1"},{"Gene":"HOMER2","Gene synonym":["CPD","Cupidin","DFNA68","HOMER-2","HOMER-2A","HOMER-2B","Vesl-2"],"Ensembl":"ENSG00000103942","Gene description":"Homer scaffold protein 2","Uniprot":["Q9NSB8"],"Chromosome":"15","Position":"82836946-82986153","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"226.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"215.9","Endometrial ciliated cells":"184.4","Glandular and luminal cells":"151.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"15.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"52.7","Karpas-707":"92.6","SCLC-21H":"50.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040134","CAB079014"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB079014":null,"HPA040134":"AB_10795272"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"6.5","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"7.6","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"26.9","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"23.1","Tissue RNA - choroid plexus [nTPM]":"69.8","Tissue RNA - colon [nTPM]":"3.2","Tissue RNA - duodenum [nTPM]":"8.5","Tissue RNA - endometrium 1 [nTPM]":"8.4","Tissue RNA - epididymis [nTPM]":"33.7","Tissue RNA - esophagus [nTPM]":"21.2","Tissue RNA - fallopian tube [nTPM]":"25.9","Tissue RNA - gallbladder [nTPM]":"12.8","Tissue RNA - heart muscle [nTPM]":"21.9","Tissue RNA - hippocampal formation [nTPM]":"16.2","Tissue RNA - hypothalamus [nTPM]":"7.8","Tissue RNA - kidney [nTPM]":"7.2","Tissue RNA - liver [nTPM]":"46.4","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"5.7","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"226.2","Tissue RNA - parathyroid gland [nTPM]":"5.1","Tissue RNA - pituitary gland [nTPM]":"7.7","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"5.7","Tissue RNA - prostate [nTPM]":"57.7","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"71.2","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"108.7","Tissue RNA - skin 1 [nTPM]":"45.0","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"4.8","Tissue RNA - stomach 1 [nTPM]":"55.4","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"28.9","Tissue RNA - tongue [nTPM]":"55.9","Tissue RNA - tonsil [nTPM]":"3.6","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"11.7","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"16.6","Cell RNA - A549 [nTPM]":"6.9","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"18.9","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"11.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"8.8","Cell RNA - fHDF\/TERT166 [nTPM]":"8.4","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"9.1","Cell RNA - HAP1 [nTPM]":"52.7","Cell RNA - HBEC3-KT [nTPM]":"24.9","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"45.1","Cell RNA - HEK 293 [nTPM]":"33.5","Cell RNA - HEL [nTPM]":"10.6","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"8.3","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"32.6","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"37.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"2.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"20.6","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"92.6","Cell RNA - LHCN-M2 [nTPM]":"7.0","Cell RNA - MCF7 [nTPM]":"48.4","Cell RNA - MOLT-4 [nTPM]":"3.2","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"11.4","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"5.1","Cell RNA - REH [nTPM]":"2.2","Cell RNA - RH-30 [nTPM]":"11.5","Cell RNA - RPMI-8226 [nTPM]":"5.5","Cell RNA - RPTEC TERT1 [nTPM]":"25.3","Cell RNA - RT4 [nTPM]":"20.1","Cell RNA - SCLC-21H [nTPM]":"50.8","Cell RNA - SH-SY5Y [nTPM]":"13.1","Cell RNA - SiHa [nTPM]":"18.6","Cell RNA - SK-BR-3 [nTPM]":"14.1","Cell RNA - SK-MEL-30 [nTPM]":"17.6","Cell RNA - SuSa [nTPM]":"5.2","Cell RNA - T-47d [nTPM]":"17.1","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"17.2","Cell RNA - U-2 OS [nTPM]":"31.7","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"15.3","Cell RNA - U-266\/70 [nTPM]":"11.8","Cell RNA - U-266\/84 [nTPM]":"5.9","Cell RNA - U-698 [nTPM]":"1.8","Cell RNA - U-87 MG [nTPM]":"29.0","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"6.4","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"6.5","Brain RNA - basal ganglia [nTPM]":"7.6","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"16.2","Brain RNA - hypothalamus [nTPM]":"7.8","Brain RNA - medulla oblongata [nTPM]":"5.7","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"5.7","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.1","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"3.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"56.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"215.9","Single Cell Type RNA - Club cells [nTPM]":"14.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"4.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"29.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"184.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.4","Single Cell Type RNA - Endothelial cells [nTPM]":"12.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"76.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"151.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"59.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.3","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"73.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"9.2","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"7.9","Single Cell Type RNA - Muller glia cells [nTPM]":"18.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"4.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"81.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"16.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"4.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"30.5"},{"Gene":"HPCA","Gene synonym":["DYT2"],"Ensembl":"ENSG00000121905","Gene description":"Hippocalcin","Uniprot":["P84074"],"Chromosome":"1","Position":"32885994-32898441","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"517.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"198.3","Early spermatids":"155.4","Late spermatids":"119.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"8.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"SCLC-21H":"4.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"1309.6","hippocampal formation":"990.7"},"Antibody":["CAB012340","HPA043245"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB012340":"AB_2120209","HPA043245":"AB_2678385"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"99.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"517.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"50.3","Tissue RNA - cerebral cortex [nTPM]":"322.2","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"37.5","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"326.8","Tissue RNA - hypothalamus [nTPM]":"52.2","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"43.0","Tissue RNA - midbrain [nTPM]":"54.8","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"41.6","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"18.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"54.8","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"105.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"82.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"4.9","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"99.4","Brain RNA - basal ganglia [nTPM]":"517.5","Brain RNA - cerebellum [nTPM]":"50.3","Brain RNA - cerebral cortex [nTPM]":"322.2","Brain RNA - hippocampal formation [nTPM]":"326.8","Brain RNA - hypothalamus [nTPM]":"52.2","Brain RNA - medulla oblongata [nTPM]":"43.0","Brain RNA - midbrain [nTPM]":"54.8","Brain RNA - pons [nTPM]":"41.6","Brain RNA - spinal cord [nTPM]":"54.8","Brain RNA - thalamus [nTPM]":"105.8","Brain RNA - white matter [nTPM]":"82.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"198.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"155.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"119.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"5.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"8.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"HPDL","Gene synonym":["4-HPPD-L","GLOXD1","MGC15668"],"Ensembl":"ENSG00000186603","Gene description":"4-hydroxyphenylpyruvate dioxygenase like","Uniprot":["Q96IR7"],"Chromosome":"1","Position":"45326895-45328679","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"29.1","Gastric mucus-secreting cells":"8.2","Undifferentiated cells":"7.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"111.7","HL-60":"34.2","NB-4":"42.8","SK-BR-3":"72.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031997","HPA057346"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA031997":"AB_10602909","HPA057346":"AB_2683415"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.81e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"1.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"111.7","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"28.7","Cell RNA - CAPAN-2 [nTPM]":"7.7","Cell RNA - Daudi [nTPM]":"5.8","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.5","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"7.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"13.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"34.2","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"2.2","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"14.6","Cell RNA - MOLT-4 [nTPM]":"22.1","Cell RNA - NB-4 [nTPM]":"42.8","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"23.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"6.6","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"19.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"22.2","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"14.6","Cell RNA - SK-BR-3 [nTPM]":"72.5","Cell RNA - SK-MEL-30 [nTPM]":"11.4","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"6.3","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"21.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"1.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"HSF4","Gene synonym":["CTM"],"Ensembl":"ENSG00000102878","Gene description":"Heat shock transcription factor 4","Uniprot":["Q9ULV5"],"Chromosome":"16","Position":"67164681-67169945","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Stress response","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"69.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"38.5","Excitatory neurons":"30.9","Horizontal cells":"43.7","Inhibitory neurons":"30.0","Leydig cells":"32.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-RPE1":"17.1","T-47d":"12.9","U-266\/70":"22.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048584"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA048584":"AB_2680452"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.24e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.19e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-3"},"Tissue RNA - adipose tissue [nTPM]":"12.4","Tissue RNA - adrenal gland [nTPM]":"23.7","Tissue RNA - amygdala [nTPM]":"43.6","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"44.3","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"12.7","Tissue RNA - cerebellum [nTPM]":"44.6","Tissue RNA - cerebral cortex [nTPM]":"69.2","Tissue RNA - cervix [nTPM]":"17.9","Tissue RNA - choroid plexus [nTPM]":"39.2","Tissue RNA - colon [nTPM]":"10.1","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"12.4","Tissue RNA - epididymis [nTPM]":"4.8","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"21.1","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"20.0","Tissue RNA - hippocampal formation [nTPM]":"44.6","Tissue RNA - hypothalamus [nTPM]":"43.7","Tissue RNA - kidney [nTPM]":"17.1","Tissue RNA - liver [nTPM]":"20.3","Tissue RNA - lung [nTPM]":"8.7","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"45.0","Tissue RNA - midbrain [nTPM]":"41.9","Tissue RNA - ovary [nTPM]":"19.8","Tissue RNA - pancreas [nTPM]":"35.9","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"30.1","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"46.4","Tissue RNA - prostate [nTPM]":"28.3","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"5.6","Tissue RNA - salivary gland [nTPM]":"19.0","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"25.9","Tissue RNA - skin 1 [nTPM]":"14.5","Tissue RNA - small intestine [nTPM]":"6.1","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"41.3","Tissue RNA - spleen [nTPM]":"6.0","Tissue RNA - stomach 1 [nTPM]":"14.4","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"43.3","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"17.9","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"18.8","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"45.8","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"3.0","Cell RNA - BEWO [nTPM]":"5.2","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.4","Cell RNA - CAPAN-2 [nTPM]":"3.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"2.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.1","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"5.9","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"2.3","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"4.5","Cell RNA - Hep G2 [nTPM]":"3.1","Cell RNA - HHSteC [nTPM]":"2.3","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"4.4","Cell RNA - HSkMC [nTPM]":"1.3","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"2.5","Cell RNA - hTERT-RPE1 [nTPM]":"17.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"4.0","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"5.1","Cell RNA - LHCN-M2 [nTPM]":"2.3","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"1.8","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"1.7","Cell RNA - RPMI-8226 [nTPM]":"8.7","Cell RNA - RPTEC TERT1 [nTPM]":"4.4","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"3.5","Cell RNA - SH-SY5Y [nTPM]":"7.6","Cell RNA - SiHa [nTPM]":"4.9","Cell RNA - SK-BR-3 [nTPM]":"3.0","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"2.1","Cell RNA - T-47d [nTPM]":"12.9","Cell RNA - THP-1 [nTPM]":"4.5","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"1.6","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"6.4","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"22.3","Cell RNA - U-266\/84 [nTPM]":"3.7","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"4.9","Cell RNA - U-937 [nTPM]":"1.7","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"43.6","Brain RNA - basal ganglia [nTPM]":"44.3","Brain RNA - cerebellum [nTPM]":"44.6","Brain RNA - cerebral cortex [nTPM]":"69.2","Brain RNA - hippocampal formation [nTPM]":"44.6","Brain RNA - hypothalamus [nTPM]":"43.7","Brain RNA - medulla oblongata [nTPM]":"45.0","Brain RNA - midbrain [nTPM]":"41.9","Brain RNA - pons [nTPM]":"46.4","Brain RNA - spinal cord [nTPM]":"41.3","Brain RNA - thalamus [nTPM]":"43.3","Brain RNA - white matter [nTPM]":"45.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"38.5","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"10.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"5.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.9","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"32.9","Single Cell Type RNA - Macrophages [nTPM]":"4.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"1.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.5","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"1.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.9","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"HSPB1","Gene synonym":["CMT2F","Hs.76067","Hsp25","HSP27","HSP28"],"Ensembl":"ENSG00000106211","Gene description":"Heat shock protein family B (small) member 1","Uniprot":["P04792"],"Chromosome":"7","Position":"76302673-76304295","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Stress response"],"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"5909.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"16589.4","Exocrine glandular cells":"6539.7","Squamous epithelial cells":"6300.1","Urothelial cells":"13091.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"2482.8","MCF7":"3979.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000497","CAB004439","CAB047330","CAB047331","CAB047332"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004439":"AB_627755","CAB047330":null,"CAB047331":null,"CAB047332":null,"HPA000497":"AB_1851172"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.94e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Tissue RNA - adipose tissue [nTPM]":"964.4","Tissue RNA - adrenal gland [nTPM]":"856.4","Tissue RNA - amygdala [nTPM]":"810.6","Tissue RNA - appendix [nTPM]":"329.6","Tissue RNA - basal ganglia [nTPM]":"835.1","Tissue RNA - bone marrow [nTPM]":"52.3","Tissue RNA - breast [nTPM]":"560.5","Tissue RNA - cerebellum [nTPM]":"821.6","Tissue RNA - cerebral cortex [nTPM]":"1798.8","Tissue RNA - cervix [nTPM]":"2123.4","Tissue RNA - choroid plexus [nTPM]":"864.3","Tissue RNA - colon [nTPM]":"2043.6","Tissue RNA - duodenum [nTPM]":"208.7","Tissue RNA - endometrium 1 [nTPM]":"2824.2","Tissue RNA - epididymis [nTPM]":"131.7","Tissue RNA - esophagus [nTPM]":"5909.6","Tissue RNA - fallopian tube [nTPM]":"993.8","Tissue RNA - gallbladder [nTPM]":"217.2","Tissue RNA - heart muscle [nTPM]":"2981.9","Tissue RNA - hippocampal formation [nTPM]":"776.6","Tissue RNA - hypothalamus [nTPM]":"944.5","Tissue RNA - kidney [nTPM]":"986.4","Tissue RNA - liver [nTPM]":"554.9","Tissue RNA - lung [nTPM]":"790.9","Tissue RNA - lymph node [nTPM]":"99.0","Tissue RNA - medulla oblongata [nTPM]":"894.1","Tissue RNA - midbrain [nTPM]":"838.7","Tissue RNA - ovary [nTPM]":"731.6","Tissue RNA - pancreas [nTPM]":"751.7","Tissue RNA - parathyroid gland [nTPM]":"221.1","Tissue RNA - pituitary gland [nTPM]":"303.3","Tissue RNA - placenta [nTPM]":"324.3","Tissue RNA - pons [nTPM]":"870.8","Tissue RNA - prostate [nTPM]":"979.0","Tissue RNA - rectum [nTPM]":"73.8","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"1075.3","Tissue RNA - seminal vesicle [nTPM]":"522.5","Tissue RNA - skeletal muscle [nTPM]":"3669.8","Tissue RNA - skin 1 [nTPM]":"2258.3","Tissue RNA - small intestine [nTPM]":"523.8","Tissue RNA - smooth muscle [nTPM]":"1066.9","Tissue RNA - spinal cord [nTPM]":"808.2","Tissue RNA - spleen [nTPM]":"224.5","Tissue RNA - stomach 1 [nTPM]":"770.3","Tissue RNA - testis [nTPM]":"99.8","Tissue RNA - thalamus [nTPM]":"840.0","Tissue RNA - thymus [nTPM]":"218.7","Tissue RNA - thyroid gland [nTPM]":"627.1","Tissue RNA - tongue [nTPM]":"628.1","Tissue RNA - tonsil [nTPM]":"279.3","Tissue RNA - urinary bladder [nTPM]":"1579.4","Tissue RNA - vagina [nTPM]":"3398.4","Tissue RNA - white matter [nTPM]":"869.5","Cell RNA - A-431 [nTPM]":"1251.1","Cell RNA - A549 [nTPM]":"902.4","Cell RNA - AF22 [nTPM]":"79.5","Cell RNA - AN3-CA [nTPM]":"576.8","Cell RNA - ASC diff [nTPM]":"487.3","Cell RNA - ASC TERT1 [nTPM]":"447.5","Cell RNA - BEWO [nTPM]":"5.1","Cell RNA - BJ [nTPM]":"514.9","Cell RNA - BJ hTERT+ [nTPM]":"249.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"260.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"325.8","Cell RNA - CACO-2 [nTPM]":"84.8","Cell RNA - CAPAN-2 [nTPM]":"660.7","Cell RNA - Daudi [nTPM]":"8.5","Cell RNA - EFO-21 [nTPM]":"389.1","Cell RNA - fHDF\/TERT166 [nTPM]":"599.1","Cell RNA - GAMG [nTPM]":"514.1","Cell RNA - HaCaT [nTPM]":"1094.2","Cell RNA - HAP1 [nTPM]":"359.0","Cell RNA - HBEC3-KT [nTPM]":"279.6","Cell RNA - HBF TERT88 [nTPM]":"76.5","Cell RNA - HDLM-2 [nTPM]":"690.9","Cell RNA - HEK 293 [nTPM]":"106.4","Cell RNA - HEL [nTPM]":"41.5","Cell RNA - HeLa [nTPM]":"611.4","Cell RNA - Hep G2 [nTPM]":"345.5","Cell RNA - HHSteC [nTPM]":"267.9","Cell RNA - HL-60 [nTPM]":"69.9","Cell RNA - HMC-1 [nTPM]":"466.5","Cell RNA - HSkMC [nTPM]":"542.8","Cell RNA - hTCEpi [nTPM]":"2482.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"370.0","Cell RNA - hTERT-HME1 [nTPM]":"50.5","Cell RNA - hTERT-RPE1 [nTPM]":"436.6","Cell RNA - HUVEC TERT2 [nTPM]":"831.3","Cell RNA - JURKAT [nTPM]":"169.5","Cell RNA - K-562 [nTPM]":"459.4","Cell RNA - Karpas-707 [nTPM]":"1079.7","Cell RNA - LHCN-M2 [nTPM]":"276.5","Cell RNA - MCF7 [nTPM]":"3979.7","Cell RNA - MOLT-4 [nTPM]":"117.1","Cell RNA - NB-4 [nTPM]":"508.9","Cell RNA - NTERA-2 [nTPM]":"407.4","Cell RNA - OE19 [nTPM]":"212.7","Cell RNA - PC-3 [nTPM]":"800.6","Cell RNA - REH [nTPM]":"417.3","Cell RNA - RH-30 [nTPM]":"195.8","Cell RNA - RPMI-8226 [nTPM]":"974.5","Cell RNA - RPTEC TERT1 [nTPM]":"342.8","Cell RNA - RT4 [nTPM]":"423.2","Cell RNA - SCLC-21H [nTPM]":"7.6","Cell RNA - SH-SY5Y [nTPM]":"529.1","Cell RNA - SiHa [nTPM]":"363.8","Cell RNA - SK-BR-3 [nTPM]":"1323.3","Cell RNA - SK-MEL-30 [nTPM]":"456.0","Cell RNA - SuSa [nTPM]":"224.5","Cell RNA - T-47d [nTPM]":"1674.9","Cell RNA - THP-1 [nTPM]":"551.6","Cell RNA - TIME [nTPM]":"504.2","Cell RNA - U-138 MG [nTPM]":"778.8","Cell RNA - U-2 OS [nTPM]":"1200.3","Cell RNA - U-2197 [nTPM]":"221.7","Cell RNA - U-251 MG [nTPM]":"1310.1","Cell RNA - U-266\/70 [nTPM]":"85.7","Cell RNA - U-266\/84 [nTPM]":"145.9","Cell RNA - U-698 [nTPM]":"10.7","Cell RNA - U-87 MG [nTPM]":"575.9","Cell RNA - U-937 [nTPM]":"247.2","Cell RNA - WM-115 [nTPM]":"579.5","Blood RNA - basophil [nTPM]":"19.7","Blood RNA - classical monocyte [nTPM]":"13.6","Blood RNA - eosinophil [nTPM]":"10.9","Blood RNA - gdT-cell [nTPM]":"58.8","Blood RNA - intermediate monocyte [nTPM]":"78.2","Blood RNA - MAIT T-cell [nTPM]":"28.1","Blood RNA - memory B-cell [nTPM]":"115.0","Blood RNA - memory CD4 T-cell [nTPM]":"92.4","Blood RNA - memory CD8 T-cell [nTPM]":"62.1","Blood RNA - myeloid DC [nTPM]":"31.5","Blood RNA - naive B-cell [nTPM]":"105.5","Blood RNA - naive CD4 T-cell [nTPM]":"102.1","Blood RNA - naive CD8 T-cell [nTPM]":"88.2","Blood RNA - neutrophil [nTPM]":"5.8","Blood RNA - NK-cell [nTPM]":"79.7","Blood RNA - non-classical monocyte [nTPM]":"112.8","Blood RNA - plasmacytoid DC [nTPM]":"56.5","Blood RNA - T-reg [nTPM]":"64.5","Blood RNA - total PBMC [nTPM]":"46.7","Brain RNA - amygdala [nTPM]":"810.6","Brain RNA - basal ganglia [nTPM]":"835.1","Brain RNA - cerebellum [nTPM]":"821.6","Brain RNA - cerebral cortex [nTPM]":"1798.8","Brain RNA - hippocampal formation [nTPM]":"776.6","Brain RNA - hypothalamus [nTPM]":"944.5","Brain RNA - medulla oblongata [nTPM]":"894.1","Brain RNA - midbrain [nTPM]":"838.7","Brain RNA - pons [nTPM]":"870.8","Brain RNA - spinal cord [nTPM]":"808.2","Brain RNA - thalamus [nTPM]":"840.0","Brain RNA - white matter [nTPM]":"869.5","Single Cell Type RNA - Adipocytes [nTPM]":"708.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"272.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"186.4","Single Cell Type RNA - Astrocytes [nTPM]":"78.4","Single Cell Type RNA - B-cells [nTPM]":"145.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1849.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16589.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3603.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1728.4","Single Cell Type RNA - Bipolar cells [nTPM]":"243.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"312.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"174.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"822.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"264.5","Single Cell Type RNA - Club cells [nTPM]":"1899.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1144.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"323.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"161.7","Single Cell Type RNA - dendritic cells [nTPM]":"62.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"824.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1500.7","Single Cell Type RNA - Ductal cells [nTPM]":"2021.4","Single Cell Type RNA - Early spermatids [nTPM]":"11.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1181.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1060.9","Single Cell Type RNA - Endothelial cells [nTPM]":"1038.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"422.0","Single Cell Type RNA - Erythroid cells [nTPM]":"136.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6539.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"399.4","Single Cell Type RNA - Fibroblasts [nTPM]":"998.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"219.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1227.1","Single Cell Type RNA - granulocytes [nTPM]":"216.7","Single Cell Type RNA - Granulosa cells [nTPM]":"136.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"725.7","Single Cell Type RNA - Hepatocytes [nTPM]":"234.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1199.8","Single Cell Type RNA - Horizontal cells [nTPM]":"70.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"433.0","Single Cell Type RNA - Ionocytes [nTPM]":"1245.1","Single Cell Type RNA - Kupffer cells [nTPM]":"147.7","Single Cell Type RNA - Langerhans cells [nTPM]":"2828.9","Single Cell Type RNA - Late spermatids [nTPM]":"30.8","Single Cell Type RNA - Leydig cells [nTPM]":"299.5","Single Cell Type RNA - Macrophages [nTPM]":"1024.8","Single Cell Type RNA - Melanocytes [nTPM]":"2056.2","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"188.0","Single Cell Type RNA - Muller glia cells [nTPM]":"171.4","Single Cell Type RNA - NK-cells [nTPM]":"50.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2719.4","Single Cell Type RNA - Paneth cells [nTPM]":"1417.1","Single Cell Type RNA - Peritubular cells [nTPM]":"534.5","Single Cell Type RNA - Plasma cells [nTPM]":"296.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3854.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"95.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2324.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1253.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Sertoli cells [nTPM]":"611.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"551.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2129.1","Single Cell Type RNA - Spermatocytes [nTPM]":"20.3","Single Cell Type RNA - Spermatogonia [nTPM]":"105.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6300.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2241.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2432.7","Single Cell Type RNA - T-cells [nTPM]":"758.2","Single Cell Type RNA - Theca cells [nTPM]":"68.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"390.5","Single Cell Type RNA - Urothelial cells [nTPM]":"13091.2"},{"Gene":"HSPB11","Gene synonym":["C1orf41","FAP232","HSPCO34","IFT25","PP25"],"Ensembl":"ENSG00000081870","Gene description":"Heat shock protein family B (small) member 11","Uniprot":["Q9Y547"],"Chromosome":"1","Position":"53916574-53945699","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Protein transport","Spermatogenesis","Stress response","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Respiratory ciliated cells":"412.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030140"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA030140":"AB_10600713"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.58e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"25.9","Tissue RNA - adrenal gland [nTPM]":"36.4","Tissue RNA - amygdala [nTPM]":"36.2","Tissue RNA - appendix [nTPM]":"34.1","Tissue RNA - basal ganglia [nTPM]":"37.1","Tissue RNA - bone marrow [nTPM]":"61.2","Tissue RNA - breast [nTPM]":"46.5","Tissue RNA - cerebellum [nTPM]":"35.5","Tissue RNA - cerebral cortex [nTPM]":"49.9","Tissue RNA - cervix [nTPM]":"33.9","Tissue RNA - choroid plexus [nTPM]":"46.4","Tissue RNA - colon [nTPM]":"31.9","Tissue RNA - duodenum [nTPM]":"25.0","Tissue RNA - endometrium 1 [nTPM]":"42.6","Tissue RNA - epididymis [nTPM]":"70.5","Tissue RNA - esophagus [nTPM]":"30.1","Tissue RNA - fallopian tube [nTPM]":"79.6","Tissue RNA - gallbladder [nTPM]":"26.8","Tissue RNA - heart muscle [nTPM]":"26.6","Tissue RNA - hippocampal formation [nTPM]":"38.4","Tissue RNA - hypothalamus [nTPM]":"36.9","Tissue RNA - kidney [nTPM]":"35.3","Tissue RNA - liver [nTPM]":"55.1","Tissue RNA - lung [nTPM]":"29.7","Tissue RNA - lymph node [nTPM]":"62.5","Tissue RNA - medulla oblongata [nTPM]":"35.5","Tissue RNA - midbrain [nTPM]":"35.5","Tissue RNA - ovary [nTPM]":"41.8","Tissue RNA - pancreas [nTPM]":"26.4","Tissue RNA - parathyroid gland [nTPM]":"30.8","Tissue RNA - pituitary gland [nTPM]":"23.1","Tissue RNA - placenta [nTPM]":"41.6","Tissue RNA - pons [nTPM]":"35.6","Tissue RNA - prostate [nTPM]":"34.9","Tissue RNA - rectum [nTPM]":"34.5","Tissue RNA - retina [nTPM]":"29.8","Tissue RNA - salivary gland [nTPM]":"24.0","Tissue RNA - seminal vesicle [nTPM]":"36.6","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"37.3","Tissue RNA - small intestine [nTPM]":"26.0","Tissue RNA - smooth muscle [nTPM]":"36.8","Tissue RNA - spinal cord [nTPM]":"36.3","Tissue RNA - spleen [nTPM]":"34.8","Tissue RNA - stomach 1 [nTPM]":"36.8","Tissue RNA - testis [nTPM]":"30.7","Tissue RNA - thalamus [nTPM]":"35.3","Tissue RNA - thymus [nTPM]":"55.8","Tissue RNA - thyroid gland [nTPM]":"96.8","Tissue RNA - tongue [nTPM]":"19.6","Tissue RNA - tonsil [nTPM]":"62.3","Tissue RNA - urinary bladder [nTPM]":"39.5","Tissue RNA - vagina [nTPM]":"19.2","Tissue RNA - white matter [nTPM]":"38.6","Cell RNA - A-431 [nTPM]":"115.4","Cell RNA - A549 [nTPM]":"50.3","Cell RNA - AF22 [nTPM]":"141.8","Cell RNA - AN3-CA [nTPM]":"31.2","Cell RNA - ASC diff [nTPM]":"51.1","Cell RNA - ASC TERT1 [nTPM]":"67.7","Cell RNA - BEWO [nTPM]":"59.4","Cell RNA - BJ [nTPM]":"95.8","Cell RNA - BJ hTERT+ [nTPM]":"91.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"142.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"163.8","Cell RNA - CACO-2 [nTPM]":"122.2","Cell RNA - CAPAN-2 [nTPM]":"60.5","Cell RNA - Daudi [nTPM]":"134.7","Cell RNA - EFO-21 [nTPM]":"77.1","Cell RNA - fHDF\/TERT166 [nTPM]":"69.6","Cell RNA - GAMG [nTPM]":"251.8","Cell RNA - HaCaT [nTPM]":"88.9","Cell RNA - HAP1 [nTPM]":"62.2","Cell RNA - HBEC3-KT [nTPM]":"99.5","Cell RNA - HBF TERT88 [nTPM]":"168.7","Cell RNA - HDLM-2 [nTPM]":"114.6","Cell RNA - HEK 293 [nTPM]":"91.6","Cell RNA - HEL [nTPM]":"166.6","Cell RNA - HeLa [nTPM]":"108.1","Cell RNA - Hep G2 [nTPM]":"163.7","Cell RNA - HHSteC [nTPM]":"58.2","Cell RNA - HL-60 [nTPM]":"83.7","Cell RNA - HMC-1 [nTPM]":"108.0","Cell RNA - HSkMC [nTPM]":"70.0","Cell RNA - hTCEpi [nTPM]":"76.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"135.5","Cell RNA - hTERT-HME1 [nTPM]":"37.0","Cell RNA - hTERT-RPE1 [nTPM]":"88.4","Cell RNA - HUVEC TERT2 [nTPM]":"77.4","Cell RNA - JURKAT [nTPM]":"82.5","Cell RNA - K-562 [nTPM]":"102.3","Cell RNA - Karpas-707 [nTPM]":"30.6","Cell RNA - LHCN-M2 [nTPM]":"184.4","Cell RNA - MCF7 [nTPM]":"24.9","Cell RNA - MOLT-4 [nTPM]":"184.8","Cell RNA - NB-4 [nTPM]":"132.4","Cell RNA - NTERA-2 [nTPM]":"59.5","Cell RNA - OE19 [nTPM]":"96.1","Cell RNA - PC-3 [nTPM]":"111.5","Cell RNA - REH [nTPM]":"125.5","Cell RNA - RH-30 [nTPM]":"184.3","Cell RNA - RPMI-8226 [nTPM]":"72.5","Cell RNA - RPTEC TERT1 [nTPM]":"118.3","Cell RNA - RT4 [nTPM]":"128.7","Cell RNA - SCLC-21H [nTPM]":"74.2","Cell RNA - SH-SY5Y [nTPM]":"59.8","Cell RNA - SiHa [nTPM]":"140.7","Cell RNA - SK-BR-3 [nTPM]":"64.8","Cell RNA - SK-MEL-30 [nTPM]":"95.4","Cell RNA - SuSa [nTPM]":"142.7","Cell RNA - T-47d [nTPM]":"396.4","Cell RNA - THP-1 [nTPM]":"118.5","Cell RNA - TIME [nTPM]":"52.7","Cell RNA - U-138 MG [nTPM]":"92.4","Cell RNA - U-2 OS [nTPM]":"115.1","Cell RNA - U-2197 [nTPM]":"104.9","Cell RNA - U-251 MG [nTPM]":"107.8","Cell RNA - U-266\/70 [nTPM]":"54.6","Cell RNA - U-266\/84 [nTPM]":"97.3","Cell RNA - U-698 [nTPM]":"141.7","Cell RNA - U-87 MG [nTPM]":"148.5","Cell RNA - U-937 [nTPM]":"78.1","Cell RNA - WM-115 [nTPM]":"81.5","Blood RNA - basophil [nTPM]":"171.2","Blood RNA - classical monocyte [nTPM]":"47.4","Blood RNA - eosinophil [nTPM]":"130.6","Blood RNA - gdT-cell [nTPM]":"87.0","Blood RNA - intermediate monocyte [nTPM]":"65.9","Blood RNA - MAIT T-cell [nTPM]":"78.8","Blood RNA - memory B-cell [nTPM]":"95.6","Blood RNA - memory CD4 T-cell [nTPM]":"85.6","Blood RNA - memory CD8 T-cell [nTPM]":"104.7","Blood RNA - myeloid DC [nTPM]":"56.8","Blood RNA - naive B-cell [nTPM]":"76.9","Blood RNA - naive CD4 T-cell [nTPM]":"67.1","Blood RNA - naive CD8 T-cell [nTPM]":"84.9","Blood RNA - neutrophil [nTPM]":"33.5","Blood RNA - NK-cell [nTPM]":"109.4","Blood RNA - non-classical monocyte [nTPM]":"71.8","Blood RNA - plasmacytoid DC [nTPM]":"121.8","Blood RNA - T-reg [nTPM]":"122.0","Blood RNA - total PBMC [nTPM]":"58.3","Brain RNA - amygdala [nTPM]":"36.2","Brain RNA - basal ganglia [nTPM]":"37.1","Brain RNA - cerebellum [nTPM]":"35.5","Brain RNA - cerebral cortex [nTPM]":"49.9","Brain RNA - hippocampal formation [nTPM]":"38.4","Brain RNA - hypothalamus [nTPM]":"36.9","Brain RNA - medulla oblongata [nTPM]":"35.5","Brain RNA - midbrain [nTPM]":"35.5","Brain RNA - pons [nTPM]":"35.6","Brain RNA - spinal cord [nTPM]":"36.3","Brain RNA - thalamus [nTPM]":"35.3","Brain RNA - white matter [nTPM]":"38.6","Single Cell Type RNA - Adipocytes [nTPM]":"37.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.4","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"54.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"106.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"79.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"244.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"68.9","Single Cell Type RNA - Bipolar cells [nTPM]":"22.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"67.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"73.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"42.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"134.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"181.9","Single Cell Type RNA - dendritic cells [nTPM]":"72.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"117.4","Single Cell Type RNA - Ductal cells [nTPM]":"60.4","Single Cell Type RNA - Early spermatids [nTPM]":"55.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"249.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"60.0","Single Cell Type RNA - Endothelial cells [nTPM]":"40.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"77.3","Single Cell Type RNA - Erythroid cells [nTPM]":"48.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"65.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"101.3","Single Cell Type RNA - Fibroblasts [nTPM]":"59.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.3","Single Cell Type RNA - granulocytes [nTPM]":"61.5","Single Cell Type RNA - Granulosa cells [nTPM]":"59.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.8","Single Cell Type RNA - Hepatocytes [nTPM]":"64.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"115.0","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"42.2","Single Cell Type RNA - Ionocytes [nTPM]":"217.7","Single Cell Type RNA - Kupffer cells [nTPM]":"46.5","Single Cell Type RNA - Langerhans cells [nTPM]":"74.8","Single Cell Type RNA - Late spermatids [nTPM]":"15.7","Single Cell Type RNA - Leydig cells [nTPM]":"61.5","Single Cell Type RNA - Macrophages [nTPM]":"57.2","Single Cell Type RNA - Melanocytes [nTPM]":"78.2","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"80.5","Single Cell Type RNA - Muller glia cells [nTPM]":"87.8","Single Cell Type RNA - NK-cells [nTPM]":"70.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"79.6","Single Cell Type RNA - Paneth cells [nTPM]":"52.0","Single Cell Type RNA - Peritubular cells [nTPM]":"63.6","Single Cell Type RNA - Plasma cells [nTPM]":"80.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"70.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"54.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"119.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"412.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.8","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"93.0","Single Cell Type RNA - Spermatocytes [nTPM]":"130.0","Single Cell Type RNA - Spermatogonia [nTPM]":"97.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"66.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"82.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"116.8","Single Cell Type RNA - T-cells [nTPM]":"73.7","Single Cell Type RNA - Theca cells [nTPM]":"120.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.7","Single Cell Type RNA - Urothelial cells [nTPM]":"118.0"},{"Gene":"HSPB3","Gene synonym":["HSPL27"],"Ensembl":"ENSG00000169271","Gene description":"Heat shock protein family B (small) member 3","Uniprot":["Q12988"],"Chromosome":"5","Position":"54455699-54456377","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Stress response"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"heart muscle":"406.9","skeletal muscle":"217.2","tongue":"218.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Cardiomyocytes":"398.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"head and neck cancer":"7.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"86.3","fHDF\/TERT166":"39.1","HSkMC":"16.3","LHCN-M2":"12.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062124"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA062124":"AB_2684690"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.4","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"5.6","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"4.1","Tissue RNA - colon [nTPM]":"5.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"7.5","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"3.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"406.9","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"2.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"4.0","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"4.4","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"217.2","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"218.9","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"3.7","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"86.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"39.1","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"16.3","Cell RNA - hTCEpi [nTPM]":"5.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"12.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"4.4","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"5.6","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"4.0","Brain RNA - pons [nTPM]":"4.4","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"398.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"3.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"HSPB8","Gene synonym":["CMT2L","E2IG1","H11","HSP22"],"Ensembl":"ENSG00000152137","Gene description":"Heat shock protein family B (small) member 8","Uniprot":["Q9UJY1"],"Chromosome":"12","Position":"119171555-119224855","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Stress response"],"Molecular function":["Chaperone"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"897.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cardiomyocytes":"599.1","Syncytiotrophoblasts":"1340.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"89.6","HeLa":"66.0","MCF7":"130.5","U-87 MG":"67.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015876"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA015876":"AB_1850458"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.98e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"57.0","Tissue RNA - adrenal gland [nTPM]":"13.9","Tissue RNA - amygdala [nTPM]":"172.2","Tissue RNA - appendix [nTPM]":"34.4","Tissue RNA - basal ganglia [nTPM]":"172.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"33.4","Tissue RNA - cerebellum [nTPM]":"179.5","Tissue RNA - cerebral cortex [nTPM]":"141.8","Tissue RNA - cervix [nTPM]":"58.1","Tissue RNA - choroid plexus [nTPM]":"147.0","Tissue RNA - colon [nTPM]":"381.0","Tissue RNA - duodenum [nTPM]":"8.9","Tissue RNA - endometrium 1 [nTPM]":"114.4","Tissue RNA - epididymis [nTPM]":"10.1","Tissue RNA - esophagus [nTPM]":"163.2","Tissue RNA - fallopian tube [nTPM]":"58.7","Tissue RNA - gallbladder [nTPM]":"43.1","Tissue RNA - heart muscle [nTPM]":"469.3","Tissue RNA - hippocampal formation [nTPM]":"147.8","Tissue RNA - hypothalamus [nTPM]":"231.0","Tissue RNA - kidney [nTPM]":"63.3","Tissue RNA - liver [nTPM]":"4.8","Tissue RNA - lung [nTPM]":"95.7","Tissue RNA - lymph node [nTPM]":"11.4","Tissue RNA - medulla oblongata [nTPM]":"188.3","Tissue RNA - midbrain [nTPM]":"206.1","Tissue RNA - ovary [nTPM]":"23.4","Tissue RNA - pancreas [nTPM]":"30.8","Tissue RNA - parathyroid gland [nTPM]":"183.1","Tissue RNA - pituitary gland [nTPM]":"17.5","Tissue RNA - placenta [nTPM]":"92.1","Tissue RNA - pons [nTPM]":"193.0","Tissue RNA - prostate [nTPM]":"143.5","Tissue RNA - rectum [nTPM]":"35.8","Tissue RNA - retina [nTPM]":"28.2","Tissue RNA - salivary gland [nTPM]":"50.8","Tissue RNA - seminal vesicle [nTPM]":"289.0","Tissue RNA - skeletal muscle [nTPM]":"897.3","Tissue RNA - skin 1 [nTPM]":"70.5","Tissue RNA - small intestine [nTPM]":"50.5","Tissue RNA - smooth muscle [nTPM]":"114.1","Tissue RNA - spinal cord [nTPM]":"211.5","Tissue RNA - spleen [nTPM]":"56.2","Tissue RNA - stomach 1 [nTPM]":"110.4","Tissue RNA - testis [nTPM]":"12.0","Tissue RNA - thalamus [nTPM]":"193.6","Tissue RNA - thymus [nTPM]":"40.3","Tissue RNA - thyroid gland [nTPM]":"29.2","Tissue RNA - tongue [nTPM]":"448.5","Tissue RNA - tonsil [nTPM]":"98.7","Tissue RNA - urinary bladder [nTPM]":"239.2","Tissue RNA - vagina [nTPM]":"100.1","Tissue RNA - white matter [nTPM]":"235.5","Cell RNA - A-431 [nTPM]":"21.1","Cell RNA - A549 [nTPM]":"16.1","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"14.4","Cell RNA - ASC TERT1 [nTPM]":"11.5","Cell RNA - BEWO [nTPM]":"60.2","Cell RNA - BJ [nTPM]":"32.5","Cell RNA - BJ hTERT+ [nTPM]":"28.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"40.0","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"89.6","Cell RNA - fHDF\/TERT166 [nTPM]":"42.4","Cell RNA - GAMG [nTPM]":"48.0","Cell RNA - HaCaT [nTPM]":"2.4","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"66.0","Cell RNA - Hep G2 [nTPM]":"3.2","Cell RNA - HHSteC [nTPM]":"11.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"14.1","Cell RNA - hTCEpi [nTPM]":"4.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.3","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"21.6","Cell RNA - HUVEC TERT2 [nTPM]":"12.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"13.0","Cell RNA - MCF7 [nTPM]":"130.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"5.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"23.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"22.9","Cell RNA - RPMI-8226 [nTPM]":"2.9","Cell RNA - RPTEC TERT1 [nTPM]":"38.3","Cell RNA - RT4 [nTPM]":"6.2","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"13.5","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"6.8","Cell RNA - SuSa [nTPM]":"50.5","Cell RNA - T-47d [nTPM]":"29.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"20.4","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"39.8","Cell RNA - U-2197 [nTPM]":"21.7","Cell RNA - U-251 MG [nTPM]":"1.7","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"67.7","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"172.2","Brain RNA - basal ganglia [nTPM]":"172.6","Brain RNA - cerebellum [nTPM]":"179.5","Brain RNA - cerebral cortex [nTPM]":"141.8","Brain RNA - hippocampal formation [nTPM]":"147.8","Brain RNA - hypothalamus [nTPM]":"231.0","Brain RNA - medulla oblongata [nTPM]":"188.3","Brain RNA - midbrain [nTPM]":"206.1","Brain RNA - pons [nTPM]":"193.0","Brain RNA - spinal cord [nTPM]":"211.5","Brain RNA - thalamus [nTPM]":"193.6","Brain RNA - white matter [nTPM]":"235.5","Single Cell Type RNA - Adipocytes [nTPM]":"2.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"48.2","Single Cell Type RNA - Astrocytes [nTPM]":"42.1","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"102.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"108.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"126.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"95.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"599.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"5.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"149.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"59.7","Single Cell Type RNA - Early spermatids [nTPM]":"12.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"98.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.2","Single Cell Type RNA - Endothelial cells [nTPM]":"27.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.5","Single Cell Type RNA - Fibroblasts [nTPM]":"82.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"142.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"9.4","Single Cell Type RNA - Late spermatids [nTPM]":"11.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"51.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"76.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1340.0","Single Cell Type RNA - T-cells [nTPM]":"3.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"72.7"},{"Gene":"HSPD1","Gene synonym":["GroEL","HSP60","SPG13"],"Ensembl":"ENSG00000144381","Gene description":"Heat shock protein family D (Hsp60) member 1","Uniprot":["P10809"],"Chromosome":"2","Position":"197486584-197516737","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Chaperone","Isomerase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary spastic paraplegia","Leukodystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"790.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"1737.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001523","CAB002775","HPA050025","CAB072816"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB002775":null,"CAB072816":null,"HPA001523":"AB_1079028","HPA050025":"AB_2680995"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"179.4","Tissue RNA - adrenal gland [nTPM]":"790.6","Tissue RNA - amygdala [nTPM]":"188.6","Tissue RNA - appendix [nTPM]":"128.3","Tissue RNA - basal ganglia [nTPM]":"191.6","Tissue RNA - bone marrow [nTPM]":"110.6","Tissue RNA - breast [nTPM]":"168.8","Tissue RNA - cerebellum [nTPM]":"204.9","Tissue RNA - cerebral cortex [nTPM]":"401.9","Tissue RNA - cervix [nTPM]":"96.9","Tissue RNA - choroid plexus [nTPM]":"217.8","Tissue RNA - colon [nTPM]":"170.0","Tissue RNA - duodenum [nTPM]":"158.1","Tissue RNA - endometrium 1 [nTPM]":"90.8","Tissue RNA - epididymis [nTPM]":"89.3","Tissue RNA - esophagus [nTPM]":"124.5","Tissue RNA - fallopian tube [nTPM]":"132.6","Tissue RNA - gallbladder [nTPM]":"69.1","Tissue RNA - heart muscle [nTPM]":"145.0","Tissue RNA - hippocampal formation [nTPM]":"184.3","Tissue RNA - hypothalamus [nTPM]":"198.6","Tissue RNA - kidney [nTPM]":"374.9","Tissue RNA - liver [nTPM]":"462.6","Tissue RNA - lung [nTPM]":"136.6","Tissue RNA - lymph node [nTPM]":"149.2","Tissue RNA - medulla oblongata [nTPM]":"199.6","Tissue RNA - midbrain [nTPM]":"198.5","Tissue RNA - ovary [nTPM]":"167.6","Tissue RNA - pancreas [nTPM]":"219.0","Tissue RNA - parathyroid gland [nTPM]":"159.2","Tissue RNA - pituitary gland [nTPM]":"116.0","Tissue RNA - placenta [nTPM]":"148.6","Tissue RNA - pons [nTPM]":"205.3","Tissue RNA - prostate [nTPM]":"104.5","Tissue RNA - rectum [nTPM]":"195.1","Tissue RNA - retina [nTPM]":"71.8","Tissue RNA - salivary gland [nTPM]":"93.9","Tissue RNA - seminal vesicle [nTPM]":"93.6","Tissue RNA - skeletal muscle [nTPM]":"162.7","Tissue RNA - skin 1 [nTPM]":"83.3","Tissue RNA - small intestine [nTPM]":"148.7","Tissue RNA - smooth muscle [nTPM]":"104.5","Tissue RNA - spinal cord [nTPM]":"195.1","Tissue RNA - spleen [nTPM]":"94.6","Tissue RNA - stomach 1 [nTPM]":"155.4","Tissue RNA - testis [nTPM]":"57.6","Tissue RNA - thalamus [nTPM]":"198.6","Tissue RNA - thymus [nTPM]":"99.3","Tissue RNA - thyroid gland [nTPM]":"138.7","Tissue RNA - tongue [nTPM]":"176.7","Tissue RNA - tonsil [nTPM]":"172.7","Tissue RNA - urinary bladder [nTPM]":"144.6","Tissue RNA - vagina [nTPM]":"92.3","Tissue RNA - white matter [nTPM]":"201.4","Cell RNA - A-431 [nTPM]":"559.7","Cell RNA - A549 [nTPM]":"650.1","Cell RNA - AF22 [nTPM]":"541.3","Cell RNA - AN3-CA [nTPM]":"496.9","Cell RNA - ASC diff [nTPM]":"373.6","Cell RNA - ASC TERT1 [nTPM]":"389.2","Cell RNA - BEWO [nTPM]":"786.5","Cell RNA - BJ [nTPM]":"573.2","Cell RNA - BJ hTERT+ [nTPM]":"304.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"686.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"495.6","Cell RNA - CACO-2 [nTPM]":"2219.1","Cell RNA - CAPAN-2 [nTPM]":"326.2","Cell RNA - Daudi [nTPM]":"1724.4","Cell RNA - EFO-21 [nTPM]":"730.0","Cell RNA - fHDF\/TERT166 [nTPM]":"304.1","Cell RNA - GAMG [nTPM]":"834.2","Cell RNA - HaCaT [nTPM]":"538.4","Cell RNA - HAP1 [nTPM]":"2232.9","Cell RNA - HBEC3-KT [nTPM]":"633.2","Cell RNA - HBF TERT88 [nTPM]":"943.0","Cell RNA - HDLM-2 [nTPM]":"417.0","Cell RNA - HEK 293 [nTPM]":"888.2","Cell RNA - HEL [nTPM]":"1209.8","Cell RNA - HeLa [nTPM]":"984.8","Cell RNA - Hep G2 [nTPM]":"2562.8","Cell RNA - HHSteC [nTPM]":"353.2","Cell RNA - HL-60 [nTPM]":"1331.4","Cell RNA - HMC-1 [nTPM]":"349.1","Cell RNA - HSkMC [nTPM]":"445.5","Cell RNA - hTCEpi [nTPM]":"717.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"599.5","Cell RNA - hTERT-HME1 [nTPM]":"1053.2","Cell RNA - hTERT-RPE1 [nTPM]":"471.4","Cell RNA - HUVEC TERT2 [nTPM]":"542.6","Cell RNA - JURKAT [nTPM]":"919.1","Cell RNA - K-562 [nTPM]":"1535.3","Cell RNA - Karpas-707 [nTPM]":"606.8","Cell RNA - LHCN-M2 [nTPM]":"501.7","Cell RNA - MCF7 [nTPM]":"690.4","Cell RNA - MOLT-4 [nTPM]":"853.6","Cell RNA - NB-4 [nTPM]":"1304.2","Cell RNA - NTERA-2 [nTPM]":"1086.4","Cell RNA - OE19 [nTPM]":"735.2","Cell RNA - PC-3 [nTPM]":"1424.9","Cell RNA - REH [nTPM]":"1000.1","Cell RNA - RH-30 [nTPM]":"679.7","Cell RNA - RPMI-8226 [nTPM]":"1235.5","Cell RNA - RPTEC TERT1 [nTPM]":"709.5","Cell RNA - RT4 [nTPM]":"539.7","Cell RNA - SCLC-21H [nTPM]":"716.5","Cell RNA - SH-SY5Y [nTPM]":"400.8","Cell RNA - SiHa [nTPM]":"582.0","Cell RNA - SK-BR-3 [nTPM]":"608.5","Cell RNA - SK-MEL-30 [nTPM]":"771.0","Cell RNA - SuSa [nTPM]":"1116.3","Cell RNA - T-47d [nTPM]":"425.0","Cell RNA - THP-1 [nTPM]":"789.4","Cell RNA - TIME [nTPM]":"242.2","Cell RNA - U-138 MG [nTPM]":"405.8","Cell RNA - U-2 OS [nTPM]":"570.4","Cell RNA - U-2197 [nTPM]":"532.8","Cell RNA - U-251 MG [nTPM]":"910.0","Cell RNA - U-266\/70 [nTPM]":"331.1","Cell RNA - U-266\/84 [nTPM]":"861.4","Cell RNA - U-698 [nTPM]":"1399.5","Cell RNA - U-87 MG [nTPM]":"485.7","Cell RNA - U-937 [nTPM]":"795.3","Cell RNA - WM-115 [nTPM]":"456.7","Blood RNA - basophil [nTPM]":"12.1","Blood RNA - classical monocyte [nTPM]":"52.3","Blood RNA - eosinophil [nTPM]":"11.4","Blood RNA - gdT-cell [nTPM]":"36.4","Blood RNA - intermediate monocyte [nTPM]":"81.8","Blood RNA - MAIT T-cell [nTPM]":"71.7","Blood RNA - memory B-cell [nTPM]":"63.8","Blood RNA - memory CD4 T-cell [nTPM]":"59.6","Blood RNA - memory CD8 T-cell [nTPM]":"54.3","Blood RNA - myeloid DC [nTPM]":"84.6","Blood RNA - naive B-cell [nTPM]":"54.0","Blood RNA - naive CD4 T-cell [nTPM]":"81.0","Blood RNA - naive CD8 T-cell [nTPM]":"70.3","Blood RNA - neutrophil [nTPM]":"11.0","Blood RNA - NK-cell [nTPM]":"62.6","Blood RNA - non-classical monocyte [nTPM]":"72.1","Blood RNA - plasmacytoid DC [nTPM]":"49.4","Blood RNA - T-reg [nTPM]":"51.8","Blood RNA - total PBMC [nTPM]":"70.6","Brain RNA - amygdala [nTPM]":"188.6","Brain RNA - basal ganglia [nTPM]":"191.6","Brain RNA - cerebellum [nTPM]":"204.9","Brain RNA - cerebral cortex [nTPM]":"401.9","Brain RNA - hippocampal formation [nTPM]":"184.3","Brain RNA - hypothalamus [nTPM]":"198.6","Brain RNA - medulla oblongata [nTPM]":"199.6","Brain RNA - midbrain [nTPM]":"198.5","Brain RNA - pons [nTPM]":"205.3","Brain RNA - spinal cord [nTPM]":"195.1","Brain RNA - thalamus [nTPM]":"198.6","Brain RNA - white matter [nTPM]":"201.4","Single Cell Type RNA - Adipocytes [nTPM]":"216.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"166.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"172.5","Single Cell Type RNA - Astrocytes [nTPM]":"38.8","Single Cell Type RNA - B-cells [nTPM]":"220.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"246.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1737.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"247.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"264.0","Single Cell Type RNA - Bipolar cells [nTPM]":"75.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"216.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"263.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"239.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"195.9","Single Cell Type RNA - Club cells [nTPM]":"287.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"256.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"825.7","Single Cell Type RNA - dendritic cells [nTPM]":"197.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"213.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"375.6","Single Cell Type RNA - Ductal cells [nTPM]":"235.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"322.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"304.5","Single Cell Type RNA - Endothelial cells [nTPM]":"233.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"274.6","Single Cell Type RNA - Erythroid cells [nTPM]":"241.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"145.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"419.8","Single Cell Type RNA - Fibroblasts [nTPM]":"356.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"215.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"445.2","Single Cell Type RNA - granulocytes [nTPM]":"299.5","Single Cell Type RNA - Granulosa cells [nTPM]":"407.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.1","Single Cell Type RNA - Hepatocytes [nTPM]":"312.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"328.0","Single Cell Type RNA - Horizontal cells [nTPM]":"95.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"302.2","Single Cell Type RNA - Ionocytes [nTPM]":"166.8","Single Cell Type RNA - Kupffer cells [nTPM]":"88.6","Single Cell Type RNA - Langerhans cells [nTPM]":"479.3","Single Cell Type RNA - Late spermatids [nTPM]":"12.8","Single Cell Type RNA - Leydig cells [nTPM]":"130.5","Single Cell Type RNA - Macrophages [nTPM]":"381.9","Single Cell Type RNA - Melanocytes [nTPM]":"163.7","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"138.5","Single Cell Type RNA - Muller glia cells [nTPM]":"125.7","Single Cell Type RNA - NK-cells [nTPM]":"68.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"171.4","Single Cell Type RNA - Paneth cells [nTPM]":"163.2","Single Cell Type RNA - Peritubular cells [nTPM]":"113.6","Single Cell Type RNA - Plasma cells [nTPM]":"322.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"705.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"160.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"797.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"328.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"117.1","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"199.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"471.7","Single Cell Type RNA - Spermatocytes [nTPM]":"88.5","Single Cell Type RNA - Spermatogonia [nTPM]":"106.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"262.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"207.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1001.2","Single Cell Type RNA - T-cells [nTPM]":"467.2","Single Cell Type RNA - Theca cells [nTPM]":"1017.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"512.1","Single Cell Type RNA - Urothelial cells [nTPM]":"861.5"},{"Gene":"HTRA1","Gene synonym":["ARMD7","HtrA","IGFBP5-protease","PRSS11"],"Ensembl":"ENSG00000166033","Gene description":"HtrA serine peptidase 1","Uniprot":["Q92743"],"Chromosome":"10","Position":"122458551-122514907","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor binding","Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"269.3","Granulosa cells":"731.6","Horizontal cells":"625.9","Muller glia cells":"373.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"2417.8","ASC TERT1":"889.4","fHDF\/TERT166":"862.3","HSkMC":"1581.4","LHCN-M2":"1238.2","U-87 MG":"1004.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036655"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":24800000,"Blood concentration - Conc. blood MS [pg\/L]":"7600000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA036655":"AB_10671966"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.90e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.62e-6"},"Tissue RNA - adipose tissue [nTPM]":"246.0","Tissue RNA - adrenal gland [nTPM]":"81.3","Tissue RNA - amygdala [nTPM]":"382.1","Tissue RNA - appendix [nTPM]":"37.0","Tissue RNA - basal ganglia [nTPM]":"436.6","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"202.8","Tissue RNA - cerebellum [nTPM]":"422.6","Tissue RNA - cerebral cortex [nTPM]":"595.7","Tissue RNA - cervix [nTPM]":"352.1","Tissue RNA - choroid plexus [nTPM]":"316.2","Tissue RNA - colon [nTPM]":"154.8","Tissue RNA - duodenum [nTPM]":"20.8","Tissue RNA - endometrium 1 [nTPM]":"197.1","Tissue RNA - epididymis [nTPM]":"247.1","Tissue RNA - esophagus [nTPM]":"57.8","Tissue RNA - fallopian tube [nTPM]":"122.9","Tissue RNA - gallbladder [nTPM]":"301.2","Tissue RNA - heart muscle [nTPM]":"114.7","Tissue RNA - hippocampal formation [nTPM]":"377.7","Tissue RNA - hypothalamus [nTPM]":"411.4","Tissue RNA - kidney [nTPM]":"230.9","Tissue RNA - liver [nTPM]":"226.4","Tissue RNA - lung [nTPM]":"69.9","Tissue RNA - lymph node [nTPM]":"39.9","Tissue RNA - medulla oblongata [nTPM]":"427.1","Tissue RNA - midbrain [nTPM]":"447.0","Tissue RNA - ovary [nTPM]":"425.5","Tissue RNA - pancreas [nTPM]":"55.9","Tissue RNA - parathyroid gland [nTPM]":"111.8","Tissue RNA - pituitary gland [nTPM]":"184.1","Tissue RNA - placenta [nTPM]":"281.9","Tissue RNA - pons [nTPM]":"425.3","Tissue RNA - prostate [nTPM]":"85.7","Tissue RNA - rectum [nTPM]":"51.8","Tissue RNA - retina [nTPM]":"243.6","Tissue RNA - salivary gland [nTPM]":"101.1","Tissue RNA - seminal vesicle [nTPM]":"114.5","Tissue RNA - skeletal muscle [nTPM]":"31.1","Tissue RNA - skin 1 [nTPM]":"130.5","Tissue RNA - small intestine [nTPM]":"73.5","Tissue RNA - smooth muscle [nTPM]":"152.3","Tissue RNA - spinal cord [nTPM]":"382.1","Tissue RNA - spleen [nTPM]":"54.2","Tissue RNA - stomach 1 [nTPM]":"87.3","Tissue RNA - testis [nTPM]":"19.5","Tissue RNA - thalamus [nTPM]":"423.6","Tissue RNA - thymus [nTPM]":"21.2","Tissue RNA - thyroid gland [nTPM]":"78.8","Tissue RNA - tongue [nTPM]":"80.9","Tissue RNA - tonsil [nTPM]":"27.3","Tissue RNA - urinary bladder [nTPM]":"137.3","Tissue RNA - vagina [nTPM]":"188.3","Tissue RNA - white matter [nTPM]":"464.2","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"45.6","Cell RNA - AF22 [nTPM]":"19.4","Cell RNA - AN3-CA [nTPM]":"5.7","Cell RNA - ASC diff [nTPM]":"2417.8","Cell RNA - ASC TERT1 [nTPM]":"889.4","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"108.3","Cell RNA - BJ hTERT+ [nTPM]":"196.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.6","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"29.0","Cell RNA - fHDF\/TERT166 [nTPM]":"862.3","Cell RNA - GAMG [nTPM]":"68.6","Cell RNA - HaCaT [nTPM]":"12.8","Cell RNA - HAP1 [nTPM]":"7.6","Cell RNA - HBEC3-KT [nTPM]":"124.4","Cell RNA - HBF TERT88 [nTPM]":"6.2","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"4.9","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"65.4","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"123.7","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"1581.4","Cell RNA - hTCEpi [nTPM]":"444.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.8","Cell RNA - hTERT-HME1 [nTPM]":"205.3","Cell RNA - hTERT-RPE1 [nTPM]":"503.6","Cell RNA - HUVEC TERT2 [nTPM]":"207.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"1238.2","Cell RNA - MCF7 [nTPM]":"22.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"20.9","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"67.6","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"1.3","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"282.6","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"3.9","Cell RNA - SiHa [nTPM]":"272.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"122.2","Cell RNA - SuSa [nTPM]":"91.4","Cell RNA - T-47d [nTPM]":"8.6","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"136.0","Cell RNA - U-138 MG [nTPM]":"309.9","Cell RNA - U-2 OS [nTPM]":"4.5","Cell RNA - U-2197 [nTPM]":"141.3","Cell RNA - U-251 MG [nTPM]":"94.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"1004.6","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"148.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"382.1","Brain RNA - basal ganglia [nTPM]":"436.6","Brain RNA - cerebellum [nTPM]":"422.6","Brain RNA - cerebral cortex [nTPM]":"595.7","Brain RNA - hippocampal formation [nTPM]":"377.7","Brain RNA - hypothalamus [nTPM]":"411.4","Brain RNA - medulla oblongata [nTPM]":"427.1","Brain RNA - midbrain [nTPM]":"447.0","Brain RNA - pons [nTPM]":"425.3","Brain RNA - spinal cord [nTPM]":"382.1","Brain RNA - thalamus [nTPM]":"423.6","Brain RNA - white matter [nTPM]":"464.2","Single Cell Type RNA - Adipocytes [nTPM]":"55.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"116.5","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"53.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"64.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"76.5","Single Cell Type RNA - Endothelial cells [nTPM]":"107.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"164.6","Single Cell Type RNA - Fibroblasts [nTPM]":"269.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"731.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"57.8","Single Cell Type RNA - Hepatocytes [nTPM]":"157.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.3","Single Cell Type RNA - Horizontal cells [nTPM]":"625.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.1","Single Cell Type RNA - Langerhans cells [nTPM]":"59.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"31.7","Single Cell Type RNA - Macrophages [nTPM]":"22.0","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"86.2","Single Cell Type RNA - monocytes [nTPM]":"8.5","Single Cell Type RNA - Muller glia cells [nTPM]":"373.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"193.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"112.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"77.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"150.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"63.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"140.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"87.7","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"2.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"11.9"},{"Gene":"HTRA2","Gene synonym":["OMI","PARK13","PRSS25"],"Ensembl":"ENSG00000115317","Gene description":"HtrA serine peptidase 2","Uniprot":["O43464"],"Chromosome":"2","Position":"74529725-74533332","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"118.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004004","HPA006602","HPA027366"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB004004":"AB_326421","HPA006602":"AB_2667622","HPA027366":"AB_1851301"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.77e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"8.7","Tissue RNA - bone marrow [nTPM]":"11.1","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"9.1","Tissue RNA - cerebral cortex [nTPM]":"9.7","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"6.9","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"8.1","Tissue RNA - hypothalamus [nTPM]":"8.3","Tissue RNA - kidney [nTPM]":"8.1","Tissue RNA - liver [nTPM]":"6.5","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"7.8","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"10.9","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"8.3","Tissue RNA - prostate [nTPM]":"4.8","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"14.5","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"9.6","Tissue RNA - thymus [nTPM]":"9.1","Tissue RNA - thyroid gland [nTPM]":"6.8","Tissue RNA - tongue [nTPM]":"9.0","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"19.1","Cell RNA - A549 [nTPM]":"14.7","Cell RNA - AF22 [nTPM]":"14.7","Cell RNA - AN3-CA [nTPM]":"12.6","Cell RNA - ASC diff [nTPM]":"21.3","Cell RNA - ASC TERT1 [nTPM]":"9.0","Cell RNA - BEWO [nTPM]":"30.1","Cell RNA - BJ [nTPM]":"17.0","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.0","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"8.5","Cell RNA - Daudi [nTPM]":"16.6","Cell RNA - EFO-21 [nTPM]":"12.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.7","Cell RNA - GAMG [nTPM]":"26.0","Cell RNA - HaCaT [nTPM]":"19.7","Cell RNA - HAP1 [nTPM]":"12.0","Cell RNA - HBEC3-KT [nTPM]":"19.6","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"34.0","Cell RNA - HEK 293 [nTPM]":"31.4","Cell RNA - HEL [nTPM]":"33.3","Cell RNA - HeLa [nTPM]":"10.8","Cell RNA - Hep G2 [nTPM]":"19.0","Cell RNA - HHSteC [nTPM]":"19.8","Cell RNA - HL-60 [nTPM]":"15.3","Cell RNA - HMC-1 [nTPM]":"22.4","Cell RNA - HSkMC [nTPM]":"9.9","Cell RNA - hTCEpi [nTPM]":"13.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.4","Cell RNA - hTERT-HME1 [nTPM]":"19.5","Cell RNA - hTERT-RPE1 [nTPM]":"18.4","Cell RNA - HUVEC TERT2 [nTPM]":"14.2","Cell RNA - JURKAT [nTPM]":"23.5","Cell RNA - K-562 [nTPM]":"43.9","Cell RNA - Karpas-707 [nTPM]":"24.9","Cell RNA - LHCN-M2 [nTPM]":"9.7","Cell RNA - MCF7 [nTPM]":"14.1","Cell RNA - MOLT-4 [nTPM]":"22.0","Cell RNA - NB-4 [nTPM]":"31.1","Cell RNA - NTERA-2 [nTPM]":"10.0","Cell RNA - OE19 [nTPM]":"22.8","Cell RNA - PC-3 [nTPM]":"37.7","Cell RNA - REH [nTPM]":"15.8","Cell RNA - RH-30 [nTPM]":"37.0","Cell RNA - RPMI-8226 [nTPM]":"17.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.6","Cell RNA - RT4 [nTPM]":"8.2","Cell RNA - SCLC-21H [nTPM]":"15.1","Cell RNA - SH-SY5Y [nTPM]":"17.7","Cell RNA - SiHa [nTPM]":"8.9","Cell RNA - SK-BR-3 [nTPM]":"18.6","Cell RNA - SK-MEL-30 [nTPM]":"32.5","Cell RNA - SuSa [nTPM]":"7.3","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"13.2","Cell RNA - TIME [nTPM]":"10.6","Cell RNA - U-138 MG [nTPM]":"19.2","Cell RNA - U-2 OS [nTPM]":"19.7","Cell RNA - U-2197 [nTPM]":"33.4","Cell RNA - U-251 MG [nTPM]":"35.3","Cell RNA - U-266\/70 [nTPM]":"29.5","Cell RNA - U-266\/84 [nTPM]":"10.2","Cell RNA - U-698 [nTPM]":"9.8","Cell RNA - U-87 MG [nTPM]":"13.6","Cell RNA - U-937 [nTPM]":"23.4","Cell RNA - WM-115 [nTPM]":"13.0","Blood RNA - basophil [nTPM]":"5.8","Blood RNA - classical monocyte [nTPM]":"7.0","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"5.8","Blood RNA - memory B-cell [nTPM]":"11.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.8","Blood RNA - memory CD8 T-cell [nTPM]":"4.1","Blood RNA - myeloid DC [nTPM]":"8.6","Blood RNA - naive B-cell [nTPM]":"9.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.3","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"5.0","Blood RNA - non-classical monocyte [nTPM]":"4.5","Blood RNA - plasmacytoid DC [nTPM]":"4.5","Blood RNA - T-reg [nTPM]":"5.7","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"8.7","Brain RNA - cerebellum [nTPM]":"9.1","Brain RNA - cerebral cortex [nTPM]":"9.7","Brain RNA - hippocampal formation [nTPM]":"8.1","Brain RNA - hypothalamus [nTPM]":"8.3","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"8.3","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"9.6","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"30.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"27.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"15.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.7","Single Cell Type RNA - dendritic cells [nTPM]":"25.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"32.4","Single Cell Type RNA - Early spermatids [nTPM]":"30.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.1","Single Cell Type RNA - Endothelial cells [nTPM]":"29.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"118.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.8","Single Cell Type RNA - Fibroblasts [nTPM]":"23.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.9","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"12.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.5","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"10.7","Single Cell Type RNA - Langerhans cells [nTPM]":"19.4","Single Cell Type RNA - Late spermatids [nTPM]":"48.9","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"14.6","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"26.3","Single Cell Type RNA - Muller glia cells [nTPM]":"20.2","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.1","Single Cell Type RNA - Paneth cells [nTPM]":"16.8","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"36.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.5","Single Cell Type RNA - Spermatocytes [nTPM]":"64.3","Single Cell Type RNA - Spermatogonia [nTPM]":"43.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.2","Single Cell Type RNA - T-cells [nTPM]":"20.6","Single Cell Type RNA - Theca cells [nTPM]":"27.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.0","Single Cell Type RNA - Urothelial cells [nTPM]":"15.7"},{"Gene":"HTT","Gene synonym":["HD","IT15"],"Ensembl":"ENSG00000197386","Gene description":"Huntingtin","Uniprot":["P42858"],"Chromosome":"4","Position":"3041363-3243960","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"181.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002756","HPA026114"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"36000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB002756":null,"HPA026114":"AB_1851330"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.41e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.3","Tissue RNA - adrenal gland [nTPM]":"9.3","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"8.2","Tissue RNA - basal ganglia [nTPM]":"11.7","Tissue RNA - bone marrow [nTPM]":"8.1","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"14.2","Tissue RNA - cervix [nTPM]":"6.1","Tissue RNA - choroid plexus [nTPM]":"8.2","Tissue RNA - colon [nTPM]":"8.1","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"7.1","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"6.7","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"7.1","Tissue RNA - hippocampal formation [nTPM]":"15.7","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"8.9","Tissue RNA - lung [nTPM]":"10.1","Tissue RNA - lymph node [nTPM]":"11.5","Tissue RNA - medulla oblongata [nTPM]":"8.7","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"7.2","Tissue RNA - pancreas [nTPM]":"21.3","Tissue RNA - parathyroid gland [nTPM]":"12.3","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"6.9","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"7.0","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"10.3","Tissue RNA - salivary gland [nTPM]":"7.2","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"15.3","Tissue RNA - skin 1 [nTPM]":"15.1","Tissue RNA - small intestine [nTPM]":"9.7","Tissue RNA - smooth muscle [nTPM]":"5.8","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"11.5","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"9.1","Tissue RNA - tongue [nTPM]":"12.4","Tissue RNA - tonsil [nTPM]":"8.8","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"11.0","Cell RNA - A-431 [nTPM]":"19.5","Cell RNA - A549 [nTPM]":"14.2","Cell RNA - AF22 [nTPM]":"17.6","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"30.9","Cell RNA - ASC TERT1 [nTPM]":"20.2","Cell RNA - BEWO [nTPM]":"17.7","Cell RNA - BJ [nTPM]":"9.0","Cell RNA - BJ hTERT+ [nTPM]":"10.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"17.3","Cell RNA - CAPAN-2 [nTPM]":"12.2","Cell RNA - Daudi [nTPM]":"28.6","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"21.6","Cell RNA - HaCaT [nTPM]":"10.7","Cell RNA - HAP1 [nTPM]":"20.6","Cell RNA - HBEC3-KT [nTPM]":"15.3","Cell RNA - HBF TERT88 [nTPM]":"12.0","Cell RNA - HDLM-2 [nTPM]":"7.8","Cell RNA - HEK 293 [nTPM]":"15.4","Cell RNA - HEL [nTPM]":"27.4","Cell RNA - HeLa [nTPM]":"18.0","Cell RNA - Hep G2 [nTPM]":"18.8","Cell RNA - HHSteC [nTPM]":"7.5","Cell RNA - HL-60 [nTPM]":"17.7","Cell RNA - HMC-1 [nTPM]":"37.9","Cell RNA - HSkMC [nTPM]":"11.1","Cell RNA - hTCEpi [nTPM]":"9.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.4","Cell RNA - hTERT-HME1 [nTPM]":"10.7","Cell RNA - hTERT-RPE1 [nTPM]":"9.3","Cell RNA - HUVEC TERT2 [nTPM]":"14.3","Cell RNA - JURKAT [nTPM]":"13.0","Cell RNA - K-562 [nTPM]":"17.7","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"11.4","Cell RNA - MCF7 [nTPM]":"17.9","Cell RNA - MOLT-4 [nTPM]":"22.4","Cell RNA - NB-4 [nTPM]":"17.1","Cell RNA - NTERA-2 [nTPM]":"21.2","Cell RNA - OE19 [nTPM]":"9.7","Cell RNA - PC-3 [nTPM]":"20.7","Cell RNA - REH [nTPM]":"17.7","Cell RNA - RH-30 [nTPM]":"16.9","Cell RNA - RPMI-8226 [nTPM]":"5.7","Cell RNA - RPTEC TERT1 [nTPM]":"14.2","Cell RNA - RT4 [nTPM]":"18.1","Cell RNA - SCLC-21H [nTPM]":"18.5","Cell RNA - SH-SY5Y [nTPM]":"13.9","Cell RNA - SiHa [nTPM]":"15.0","Cell RNA - SK-BR-3 [nTPM]":"5.7","Cell RNA - SK-MEL-30 [nTPM]":"14.6","Cell RNA - SuSa [nTPM]":"12.9","Cell RNA - T-47d [nTPM]":"16.1","Cell RNA - THP-1 [nTPM]":"10.8","Cell RNA - TIME [nTPM]":"20.6","Cell RNA - U-138 MG [nTPM]":"16.8","Cell RNA - U-2 OS [nTPM]":"11.1","Cell RNA - U-2197 [nTPM]":"12.4","Cell RNA - U-251 MG [nTPM]":"19.0","Cell RNA - U-266\/70 [nTPM]":"7.6","Cell RNA - U-266\/84 [nTPM]":"8.8","Cell RNA - U-698 [nTPM]":"22.9","Cell RNA - U-87 MG [nTPM]":"13.4","Cell RNA - U-937 [nTPM]":"16.4","Cell RNA - WM-115 [nTPM]":"13.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"11.7","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"14.2","Brain RNA - hippocampal formation [nTPM]":"15.7","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"8.7","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"11.0","Single Cell Type RNA - Adipocytes [nTPM]":"15.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.8","Single Cell Type RNA - Astrocytes [nTPM]":"41.1","Single Cell Type RNA - B-cells [nTPM]":"20.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"48.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"14.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"181.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.8","Single Cell Type RNA - dendritic cells [nTPM]":"26.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.0","Single Cell Type RNA - Early spermatids [nTPM]":"9.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.8","Single Cell Type RNA - Endothelial cells [nTPM]":"17.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.5","Single Cell Type RNA - Erythroid cells [nTPM]":"18.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.7","Single Cell Type RNA - Fibroblasts [nTPM]":"13.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.3","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"54.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"17.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.7","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"75.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"23.4","Single Cell Type RNA - Langerhans cells [nTPM]":"15.4","Single Cell Type RNA - Late spermatids [nTPM]":"10.3","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"25.4","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"18.2","Single Cell Type RNA - Muller glia cells [nTPM]":"20.8","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"59.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"52.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.0","Single Cell Type RNA - Paneth cells [nTPM]":"21.2","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"15.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.6","Single Cell Type RNA - Spermatocytes [nTPM]":"13.0","Single Cell Type RNA - Spermatogonia [nTPM]":"21.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - T-cells [nTPM]":"19.5","Single Cell Type RNA - Theca cells [nTPM]":"16.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"11.6"},{"Gene":"IBA57","Gene synonym":["C1orf69","FLJ12734"],"Ensembl":"ENSG00000181873","Gene description":"Iron-sulfur cluster assembly factor IBA57","Uniprot":["Q5T440"],"Chromosome":"1","Position":"228165804-228182257","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Heme biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"49.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030555","HPA030556","HPA030557"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA030555":"AB_2673522","HPA030556":"AB_2673523","HPA030557":"AB_10670433"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.71e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"2.7","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"4.1","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"2.5","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"1.8","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"6.1","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"1.7","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"4.0","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.2","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"2.5","Cell RNA - A549 [nTPM]":"2.5","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"1.2","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"1.4","Cell RNA - BEWO [nTPM]":"3.3","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"5.3","Cell RNA - CAPAN-2 [nTPM]":"2.1","Cell RNA - Daudi [nTPM]":"5.3","Cell RNA - EFO-21 [nTPM]":"3.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.6","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"2.0","Cell RNA - HBEC3-KT [nTPM]":"3.2","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"4.5","Cell RNA - HEL [nTPM]":"3.1","Cell RNA - HeLa [nTPM]":"3.5","Cell RNA - Hep G2 [nTPM]":"2.6","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"3.5","Cell RNA - HSkMC [nTPM]":"2.2","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.3","Cell RNA - hTERT-HME1 [nTPM]":"1.5","Cell RNA - hTERT-RPE1 [nTPM]":"1.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.6","Cell RNA - JURKAT [nTPM]":"3.2","Cell RNA - K-562 [nTPM]":"5.4","Cell RNA - Karpas-707 [nTPM]":"2.4","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"2.0","Cell RNA - MOLT-4 [nTPM]":"3.6","Cell RNA - NB-4 [nTPM]":"2.2","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"2.8","Cell RNA - REH [nTPM]":"4.4","Cell RNA - RH-30 [nTPM]":"3.1","Cell RNA - RPMI-8226 [nTPM]":"2.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"5.1","Cell RNA - SCLC-21H [nTPM]":"4.1","Cell RNA - SH-SY5Y [nTPM]":"2.8","Cell RNA - SiHa [nTPM]":"2.4","Cell RNA - SK-BR-3 [nTPM]":"7.5","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"6.0","Cell RNA - THP-1 [nTPM]":"4.9","Cell RNA - TIME [nTPM]":"3.8","Cell RNA - U-138 MG [nTPM]":"3.0","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"3.7","Cell RNA - U-266\/70 [nTPM]":"1.8","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"2.6","Cell RNA - U-87 MG [nTPM]":"1.4","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"2.3","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"2.5","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"5.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"10.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.7","Single Cell Type RNA - dendritic cells [nTPM]":"5.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"22.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"49.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.6","Single Cell Type RNA - Fibroblasts [nTPM]":"5.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"7.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.4","Single Cell Type RNA - Late spermatids [nTPM]":"30.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"6.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"4.2","Single Cell Type RNA - Muller glia cells [nTPM]":"4.4","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"6.3","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"5.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.7","Single Cell Type RNA - Spermatocytes [nTPM]":"14.9","Single Cell Type RNA - Spermatogonia [nTPM]":"11.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"8.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.9","Single Cell Type RNA - Urothelial cells [nTPM]":"8.3"},{"Gene":"IDH3A","Gene synonym":[],"Ensembl":"ENSG00000166411","Gene description":"Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha","Uniprot":["P50213"],"Chromosome":"15","Position":"78131498-78171945","Protein class":["Citric acid cycle related proteins","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"99.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"144.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041465","HPA062971"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA041465":"AB_10794377","HPA062971":"AB_2684913"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.49e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.6","Tissue RNA - adrenal gland [nTPM]":"25.1","Tissue RNA - amygdala [nTPM]":"11.5","Tissue RNA - appendix [nTPM]":"19.9","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"9.7","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"17.0","Tissue RNA - cerebral cortex [nTPM]":"14.7","Tissue RNA - cervix [nTPM]":"12.4","Tissue RNA - choroid plexus [nTPM]":"21.4","Tissue RNA - colon [nTPM]":"26.2","Tissue RNA - duodenum [nTPM]":"36.6","Tissue RNA - endometrium 1 [nTPM]":"13.7","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"17.0","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"62.5","Tissue RNA - hippocampal formation [nTPM]":"14.8","Tissue RNA - hypothalamus [nTPM]":"13.2","Tissue RNA - kidney [nTPM]":"16.8","Tissue RNA - liver [nTPM]":"14.2","Tissue RNA - lung [nTPM]":"11.9","Tissue RNA - lymph node [nTPM]":"17.1","Tissue RNA - medulla oblongata [nTPM]":"13.0","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"10.8","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"54.7","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"15.2","Tissue RNA - prostate [nTPM]":"13.9","Tissue RNA - rectum [nTPM]":"26.7","Tissue RNA - retina [nTPM]":"26.2","Tissue RNA - salivary gland [nTPM]":"16.2","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"79.4","Tissue RNA - skin 1 [nTPM]":"15.8","Tissue RNA - small intestine [nTPM]":"36.0","Tissue RNA - smooth muscle [nTPM]":"17.1","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"15.3","Tissue RNA - stomach 1 [nTPM]":"11.9","Tissue RNA - testis [nTPM]":"16.9","Tissue RNA - thalamus [nTPM]":"14.3","Tissue RNA - thymus [nTPM]":"35.0","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"99.7","Tissue RNA - tonsil [nTPM]":"24.8","Tissue RNA - urinary bladder [nTPM]":"17.7","Tissue RNA - vagina [nTPM]":"11.1","Tissue RNA - white matter [nTPM]":"14.8","Cell RNA - A-431 [nTPM]":"43.8","Cell RNA - A549 [nTPM]":"58.5","Cell RNA - AF22 [nTPM]":"10.4","Cell RNA - AN3-CA [nTPM]":"36.5","Cell RNA - ASC diff [nTPM]":"25.5","Cell RNA - ASC TERT1 [nTPM]":"26.1","Cell RNA - BEWO [nTPM]":"22.6","Cell RNA - BJ [nTPM]":"50.8","Cell RNA - BJ hTERT+ [nTPM]":"24.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.5","Cell RNA - CACO-2 [nTPM]":"41.6","Cell RNA - CAPAN-2 [nTPM]":"25.8","Cell RNA - Daudi [nTPM]":"91.6","Cell RNA - EFO-21 [nTPM]":"36.8","Cell RNA - fHDF\/TERT166 [nTPM]":"29.9","Cell RNA - GAMG [nTPM]":"59.9","Cell RNA - HaCaT [nTPM]":"64.2","Cell RNA - HAP1 [nTPM]":"98.2","Cell RNA - HBEC3-KT [nTPM]":"39.3","Cell RNA - HBF TERT88 [nTPM]":"37.0","Cell RNA - HDLM-2 [nTPM]":"40.7","Cell RNA - HEK 293 [nTPM]":"32.2","Cell RNA - HEL [nTPM]":"35.7","Cell RNA - HeLa [nTPM]":"62.4","Cell RNA - Hep G2 [nTPM]":"19.2","Cell RNA - HHSteC [nTPM]":"21.8","Cell RNA - HL-60 [nTPM]":"69.8","Cell RNA - HMC-1 [nTPM]":"48.8","Cell RNA - HSkMC [nTPM]":"19.9","Cell RNA - hTCEpi [nTPM]":"23.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.4","Cell RNA - hTERT-HME1 [nTPM]":"41.2","Cell RNA - hTERT-RPE1 [nTPM]":"19.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.7","Cell RNA - JURKAT [nTPM]":"32.0","Cell RNA - K-562 [nTPM]":"46.4","Cell RNA - Karpas-707 [nTPM]":"35.9","Cell RNA - LHCN-M2 [nTPM]":"26.0","Cell RNA - MCF7 [nTPM]":"41.4","Cell RNA - MOLT-4 [nTPM]":"51.4","Cell RNA - NB-4 [nTPM]":"17.4","Cell RNA - NTERA-2 [nTPM]":"12.9","Cell RNA - OE19 [nTPM]":"25.2","Cell RNA - PC-3 [nTPM]":"21.8","Cell RNA - REH [nTPM]":"29.3","Cell RNA - RH-30 [nTPM]":"44.4","Cell RNA - RPMI-8226 [nTPM]":"28.1","Cell RNA - RPTEC TERT1 [nTPM]":"33.4","Cell RNA - RT4 [nTPM]":"58.3","Cell RNA - SCLC-21H [nTPM]":"41.4","Cell RNA - SH-SY5Y [nTPM]":"15.8","Cell RNA - SiHa [nTPM]":"58.2","Cell RNA - SK-BR-3 [nTPM]":"82.1","Cell RNA - SK-MEL-30 [nTPM]":"47.1","Cell RNA - SuSa [nTPM]":"19.1","Cell RNA - T-47d [nTPM]":"32.7","Cell RNA - THP-1 [nTPM]":"37.4","Cell RNA - TIME [nTPM]":"26.4","Cell RNA - U-138 MG [nTPM]":"47.6","Cell RNA - U-2 OS [nTPM]":"43.9","Cell RNA - U-2197 [nTPM]":"63.1","Cell RNA - U-251 MG [nTPM]":"83.1","Cell RNA - U-266\/70 [nTPM]":"41.5","Cell RNA - U-266\/84 [nTPM]":"99.9","Cell RNA - U-698 [nTPM]":"48.8","Cell RNA - U-87 MG [nTPM]":"33.2","Cell RNA - U-937 [nTPM]":"64.9","Cell RNA - WM-115 [nTPM]":"37.7","Blood RNA - basophil [nTPM]":"16.9","Blood RNA - classical monocyte [nTPM]":"27.9","Blood RNA - eosinophil [nTPM]":"8.3","Blood RNA - gdT-cell [nTPM]":"15.1","Blood RNA - intermediate monocyte [nTPM]":"52.9","Blood RNA - MAIT T-cell [nTPM]":"16.4","Blood RNA - memory B-cell [nTPM]":"27.7","Blood RNA - memory CD4 T-cell [nTPM]":"14.7","Blood RNA - memory CD8 T-cell [nTPM]":"13.5","Blood RNA - myeloid DC [nTPM]":"43.5","Blood RNA - naive B-cell [nTPM]":"32.6","Blood RNA - naive CD4 T-cell [nTPM]":"15.2","Blood RNA - naive CD8 T-cell [nTPM]":"16.4","Blood RNA - neutrophil [nTPM]":"15.5","Blood RNA - NK-cell [nTPM]":"17.3","Blood RNA - non-classical monocyte [nTPM]":"54.8","Blood RNA - plasmacytoid DC [nTPM]":"144.4","Blood RNA - T-reg [nTPM]":"17.7","Blood RNA - total PBMC [nTPM]":"23.2","Brain RNA - amygdala [nTPM]":"11.5","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"17.0","Brain RNA - cerebral cortex [nTPM]":"14.7","Brain RNA - hippocampal formation [nTPM]":"14.8","Brain RNA - hypothalamus [nTPM]":"13.2","Brain RNA - medulla oblongata [nTPM]":"13.0","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"15.2","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"14.3","Brain RNA - white matter [nTPM]":"14.8","Single Cell Type RNA - Adipocytes [nTPM]":"18.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.5","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"30.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"58.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"51.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"35.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"22.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.3","Single Cell Type RNA - dendritic cells [nTPM]":"63.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"69.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"82.2","Single Cell Type RNA - Ductal cells [nTPM]":"26.1","Single Cell Type RNA - Early spermatids [nTPM]":"52.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.4","Single Cell Type RNA - Endothelial cells [nTPM]":"17.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.4","Single Cell Type RNA - Fibroblasts [nTPM]":"21.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.2","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"22.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.5","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.6","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"24.9","Single Cell Type RNA - Langerhans cells [nTPM]":"28.6","Single Cell Type RNA - Late spermatids [nTPM]":"23.4","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"26.4","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"16.0","Single Cell Type RNA - Muller glia cells [nTPM]":"29.3","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.5","Single Cell Type RNA - Paneth cells [nTPM]":"37.9","Single Cell Type RNA - Peritubular cells [nTPM]":"23.7","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"49.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.5","Single Cell Type RNA - Spermatocytes [nTPM]":"45.7","Single Cell Type RNA - Spermatogonia [nTPM]":"26.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"68.4","Single Cell Type RNA - T-cells [nTPM]":"17.7","Single Cell Type RNA - Theca cells [nTPM]":"37.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"56.0","Single Cell Type RNA - Urothelial cells [nTPM]":"42.0"},{"Gene":"IDH3B","Gene synonym":["RP46"],"Ensembl":"ENSG00000101365","Gene description":"Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta","Uniprot":["O43837"],"Chromosome":"20","Position":"2658395-2664219","Protein class":["Citric acid cycle related proteins","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049387","HPA054180"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8300","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA049387":"AB_2680740","HPA054180":"AB_2682407"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.78e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"55.6","Tissue RNA - adrenal gland [nTPM]":"61.3","Tissue RNA - amygdala [nTPM]":"51.8","Tissue RNA - appendix [nTPM]":"33.4","Tissue RNA - basal ganglia [nTPM]":"53.0","Tissue RNA - bone marrow [nTPM]":"57.9","Tissue RNA - breast [nTPM]":"54.7","Tissue RNA - cerebellum [nTPM]":"60.8","Tissue RNA - cerebral cortex [nTPM]":"57.9","Tissue RNA - cervix [nTPM]":"56.6","Tissue RNA - choroid plexus [nTPM]":"49.4","Tissue RNA - colon [nTPM]":"70.8","Tissue RNA - duodenum [nTPM]":"73.9","Tissue RNA - endometrium 1 [nTPM]":"57.3","Tissue RNA - epididymis [nTPM]":"35.9","Tissue RNA - esophagus [nTPM]":"62.4","Tissue RNA - fallopian tube [nTPM]":"49.8","Tissue RNA - gallbladder [nTPM]":"29.6","Tissue RNA - heart muscle [nTPM]":"185.8","Tissue RNA - hippocampal formation [nTPM]":"53.8","Tissue RNA - hypothalamus [nTPM]":"56.3","Tissue RNA - kidney [nTPM]":"71.0","Tissue RNA - liver [nTPM]":"60.5","Tissue RNA - lung [nTPM]":"43.9","Tissue RNA - lymph node [nTPM]":"41.9","Tissue RNA - medulla oblongata [nTPM]":"58.0","Tissue RNA - midbrain [nTPM]":"54.0","Tissue RNA - ovary [nTPM]":"57.7","Tissue RNA - pancreas [nTPM]":"46.0","Tissue RNA - parathyroid gland [nTPM]":"75.3","Tissue RNA - pituitary gland [nTPM]":"36.8","Tissue RNA - placenta [nTPM]":"41.1","Tissue RNA - pons [nTPM]":"60.0","Tissue RNA - prostate [nTPM]":"45.7","Tissue RNA - rectum [nTPM]":"59.7","Tissue RNA - retina [nTPM]":"46.1","Tissue RNA - salivary gland [nTPM]":"49.1","Tissue RNA - seminal vesicle [nTPM]":"43.1","Tissue RNA - skeletal muscle [nTPM]":"204.0","Tissue RNA - skin 1 [nTPM]":"61.9","Tissue RNA - small intestine [nTPM]":"59.9","Tissue RNA - smooth muscle [nTPM]":"44.7","Tissue RNA - spinal cord [nTPM]":"50.6","Tissue RNA - spleen [nTPM]":"53.1","Tissue RNA - stomach 1 [nTPM]":"63.7","Tissue RNA - testis [nTPM]":"36.6","Tissue RNA - thalamus [nTPM]":"56.6","Tissue RNA - thymus [nTPM]":"59.5","Tissue RNA - thyroid gland [nTPM]":"49.4","Tissue RNA - tongue [nTPM]":"236.6","Tissue RNA - tonsil [nTPM]":"56.5","Tissue RNA - urinary bladder [nTPM]":"55.5","Tissue RNA - vagina [nTPM]":"53.4","Tissue RNA - white matter [nTPM]":"56.0","Cell RNA - A-431 [nTPM]":"111.6","Cell RNA - A549 [nTPM]":"147.4","Cell RNA - AF22 [nTPM]":"66.0","Cell RNA - AN3-CA [nTPM]":"57.9","Cell RNA - ASC diff [nTPM]":"71.3","Cell RNA - ASC TERT1 [nTPM]":"55.9","Cell RNA - BEWO [nTPM]":"76.0","Cell RNA - BJ [nTPM]":"58.2","Cell RNA - BJ hTERT+ [nTPM]":"74.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"134.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"106.7","Cell RNA - CACO-2 [nTPM]":"191.4","Cell RNA - CAPAN-2 [nTPM]":"113.4","Cell RNA - Daudi [nTPM]":"124.5","Cell RNA - EFO-21 [nTPM]":"52.2","Cell RNA - fHDF\/TERT166 [nTPM]":"80.4","Cell RNA - GAMG [nTPM]":"123.7","Cell RNA - HaCaT [nTPM]":"152.7","Cell RNA - HAP1 [nTPM]":"122.9","Cell RNA - HBEC3-KT [nTPM]":"189.0","Cell RNA - HBF TERT88 [nTPM]":"122.6","Cell RNA - HDLM-2 [nTPM]":"34.7","Cell RNA - HEK 293 [nTPM]":"96.7","Cell RNA - HEL [nTPM]":"151.2","Cell RNA - HeLa [nTPM]":"58.4","Cell RNA - Hep G2 [nTPM]":"200.6","Cell RNA - HHSteC [nTPM]":"69.7","Cell RNA - HL-60 [nTPM]":"166.5","Cell RNA - HMC-1 [nTPM]":"31.8","Cell RNA - HSkMC [nTPM]":"74.4","Cell RNA - hTCEpi [nTPM]":"71.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"125.9","Cell RNA - hTERT-HME1 [nTPM]":"65.7","Cell RNA - hTERT-RPE1 [nTPM]":"59.2","Cell RNA - HUVEC TERT2 [nTPM]":"80.4","Cell RNA - JURKAT [nTPM]":"105.6","Cell RNA - K-562 [nTPM]":"194.9","Cell RNA - Karpas-707 [nTPM]":"67.7","Cell RNA - LHCN-M2 [nTPM]":"83.0","Cell RNA - MCF7 [nTPM]":"61.1","Cell RNA - MOLT-4 [nTPM]":"146.1","Cell RNA - NB-4 [nTPM]":"190.4","Cell RNA - NTERA-2 [nTPM]":"128.3","Cell RNA - OE19 [nTPM]":"113.4","Cell RNA - PC-3 [nTPM]":"137.9","Cell RNA - REH [nTPM]":"117.7","Cell RNA - RH-30 [nTPM]":"120.2","Cell RNA - RPMI-8226 [nTPM]":"140.2","Cell RNA - RPTEC TERT1 [nTPM]":"77.7","Cell RNA - RT4 [nTPM]":"102.5","Cell RNA - SCLC-21H [nTPM]":"118.5","Cell RNA - SH-SY5Y [nTPM]":"85.5","Cell RNA - SiHa [nTPM]":"71.9","Cell RNA - SK-BR-3 [nTPM]":"235.0","Cell RNA - SK-MEL-30 [nTPM]":"127.3","Cell RNA - SuSa [nTPM]":"50.8","Cell RNA - T-47d [nTPM]":"118.1","Cell RNA - THP-1 [nTPM]":"73.0","Cell RNA - TIME [nTPM]":"72.4","Cell RNA - U-138 MG [nTPM]":"104.2","Cell RNA - U-2 OS [nTPM]":"65.4","Cell RNA - U-2197 [nTPM]":"35.8","Cell RNA - U-251 MG [nTPM]":"136.3","Cell RNA - U-266\/70 [nTPM]":"91.2","Cell RNA - U-266\/84 [nTPM]":"225.3","Cell RNA - U-698 [nTPM]":"129.8","Cell RNA - U-87 MG [nTPM]":"49.1","Cell RNA - U-937 [nTPM]":"169.9","Cell RNA - WM-115 [nTPM]":"101.2","Blood RNA - basophil [nTPM]":"76.0","Blood RNA - classical monocyte [nTPM]":"111.7","Blood RNA - eosinophil [nTPM]":"72.2","Blood RNA - gdT-cell [nTPM]":"84.9","Blood RNA - intermediate monocyte [nTPM]":"120.8","Blood RNA - MAIT T-cell [nTPM]":"64.5","Blood RNA - memory B-cell [nTPM]":"96.3","Blood RNA - memory CD4 T-cell [nTPM]":"72.8","Blood RNA - memory CD8 T-cell [nTPM]":"77.7","Blood RNA - myeloid DC [nTPM]":"131.9","Blood RNA - naive B-cell [nTPM]":"84.6","Blood RNA - naive CD4 T-cell [nTPM]":"84.6","Blood RNA - naive CD8 T-cell [nTPM]":"73.1","Blood RNA - neutrophil [nTPM]":"31.4","Blood RNA - NK-cell [nTPM]":"84.8","Blood RNA - non-classical monocyte [nTPM]":"110.9","Blood RNA - plasmacytoid DC [nTPM]":"61.2","Blood RNA - T-reg [nTPM]":"108.1","Blood RNA - total PBMC [nTPM]":"102.1","Brain RNA - amygdala [nTPM]":"51.8","Brain RNA - basal ganglia [nTPM]":"53.0","Brain RNA - cerebellum [nTPM]":"60.8","Brain RNA - cerebral cortex [nTPM]":"57.9","Brain RNA - hippocampal formation [nTPM]":"53.8","Brain RNA - hypothalamus [nTPM]":"56.3","Brain RNA - medulla oblongata [nTPM]":"58.0","Brain RNA - midbrain [nTPM]":"54.0","Brain RNA - pons [nTPM]":"60.0","Brain RNA - spinal cord [nTPM]":"50.6","Brain RNA - thalamus [nTPM]":"56.6","Brain RNA - white matter [nTPM]":"56.0","Single Cell Type RNA - Adipocytes [nTPM]":"50.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.2","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"52.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"60.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"103.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"48.9","Single Cell Type RNA - Bipolar cells [nTPM]":"37.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"186.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"49.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"133.9","Single Cell Type RNA - dendritic cells [nTPM]":"71.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"81.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"156.5","Single Cell Type RNA - Ductal cells [nTPM]":"88.5","Single Cell Type RNA - Early spermatids [nTPM]":"59.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.0","Single Cell Type RNA - Endothelial cells [nTPM]":"53.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"50.7","Single Cell Type RNA - Erythroid cells [nTPM]":"41.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"102.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"86.3","Single Cell Type RNA - Fibroblasts [nTPM]":"49.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.9","Single Cell Type RNA - granulocytes [nTPM]":"48.2","Single Cell Type RNA - Granulosa cells [nTPM]":"54.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.7","Single Cell Type RNA - Hepatocytes [nTPM]":"55.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"97.6","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"68.4","Single Cell Type RNA - Ionocytes [nTPM]":"71.2","Single Cell Type RNA - Kupffer cells [nTPM]":"57.7","Single Cell Type RNA - Langerhans cells [nTPM]":"60.9","Single Cell Type RNA - Late spermatids [nTPM]":"115.1","Single Cell Type RNA - Leydig cells [nTPM]":"45.1","Single Cell Type RNA - Macrophages [nTPM]":"51.7","Single Cell Type RNA - Melanocytes [nTPM]":"69.4","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"78.7","Single Cell Type RNA - Muller glia cells [nTPM]":"49.3","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"70.8","Single Cell Type RNA - Paneth cells [nTPM]":"72.5","Single Cell Type RNA - Peritubular cells [nTPM]":"47.4","Single Cell Type RNA - Plasma cells [nTPM]":"38.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"121.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"174.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.4","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"50.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"64.1","Single Cell Type RNA - Spermatocytes [nTPM]":"52.8","Single Cell Type RNA - Spermatogonia [nTPM]":"55.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"48.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"60.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"108.5","Single Cell Type RNA - T-cells [nTPM]":"49.1","Single Cell Type RNA - Theca cells [nTPM]":"63.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"113.7","Single Cell Type RNA - Urothelial cells [nTPM]":"54.3"},{"Gene":"IFT140","Gene synonym":["gs114","KIAA0590","WDTC2"],"Ensembl":"ENSG00000187535","Gene description":"Intraflagellar transport 140","Uniprot":["Q96RY7"],"Chromosome":"16","Position":"1510427-1612072","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"27.8","Late spermatids":"25.6","Respiratory ciliated cells":"31.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"3.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042197"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042197":"AB_2677895"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-3"},"Tissue RNA - adipose tissue [nTPM]":"5.5","Tissue RNA - adrenal gland [nTPM]":"8.9","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"13.2","Tissue RNA - cervix [nTPM]":"11.3","Tissue RNA - choroid plexus [nTPM]":"20.8","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"4.1","Tissue RNA - fallopian tube [nTPM]":"15.3","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"4.9","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"11.8","Tissue RNA - kidney [nTPM]":"10.4","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"8.7","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"14.8","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"8.4","Tissue RNA - pituitary gland [nTPM]":"15.7","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"9.5","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"5.6","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"10.2","Tissue RNA - spleen [nTPM]":"4.1","Tissue RNA - stomach 1 [nTPM]":"6.8","Tissue RNA - testis [nTPM]":"15.3","Tissue RNA - thalamus [nTPM]":"11.6","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"22.9","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"12.0","Tissue RNA - vagina [nTPM]":"7.2","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"2.0","Cell RNA - A549 [nTPM]":"12.4","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"9.6","Cell RNA - ASC diff [nTPM]":"8.0","Cell RNA - ASC TERT1 [nTPM]":"5.9","Cell RNA - BEWO [nTPM]":"5.4","Cell RNA - BJ [nTPM]":"2.6","Cell RNA - BJ hTERT+ [nTPM]":"9.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.3","Cell RNA - CACO-2 [nTPM]":"3.4","Cell RNA - CAPAN-2 [nTPM]":"9.9","Cell RNA - Daudi [nTPM]":"3.8","Cell RNA - EFO-21 [nTPM]":"7.3","Cell RNA - fHDF\/TERT166 [nTPM]":"3.9","Cell RNA - GAMG [nTPM]":"3.6","Cell RNA - HaCaT [nTPM]":"7.5","Cell RNA - HAP1 [nTPM]":"1.7","Cell RNA - HBEC3-KT [nTPM]":"1.5","Cell RNA - HBF TERT88 [nTPM]":"1.9","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"7.6","Cell RNA - HEL [nTPM]":"2.3","Cell RNA - HeLa [nTPM]":"9.3","Cell RNA - Hep G2 [nTPM]":"8.3","Cell RNA - HHSteC [nTPM]":"6.9","Cell RNA - HL-60 [nTPM]":"1.3","Cell RNA - HMC-1 [nTPM]":"4.7","Cell RNA - HSkMC [nTPM]":"8.4","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.2","Cell RNA - hTERT-HME1 [nTPM]":"4.2","Cell RNA - hTERT-RPE1 [nTPM]":"10.5","Cell RNA - HUVEC TERT2 [nTPM]":"2.0","Cell RNA - JURKAT [nTPM]":"7.6","Cell RNA - K-562 [nTPM]":"2.6","Cell RNA - Karpas-707 [nTPM]":"2.2","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"12.0","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"3.9","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"2.5","Cell RNA - PC-3 [nTPM]":"2.9","Cell RNA - REH [nTPM]":"6.3","Cell RNA - RH-30 [nTPM]":"3.4","Cell RNA - RPMI-8226 [nTPM]":"5.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.3","Cell RNA - RT4 [nTPM]":"6.2","Cell RNA - SCLC-21H [nTPM]":"18.0","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"2.9","Cell RNA - SK-BR-3 [nTPM]":"5.0","Cell RNA - SK-MEL-30 [nTPM]":"3.9","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"17.4","Cell RNA - THP-1 [nTPM]":"5.1","Cell RNA - TIME [nTPM]":"3.9","Cell RNA - U-138 MG [nTPM]":"2.2","Cell RNA - U-2 OS [nTPM]":"7.0","Cell RNA - U-2197 [nTPM]":"4.0","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"6.8","Cell RNA - U-266\/84 [nTPM]":"2.6","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"3.7","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"13.2","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"11.8","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"14.8","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"10.2","Brain RNA - thalamus [nTPM]":"11.6","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"2.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.2","Single Cell Type RNA - Early spermatids [nTPM]":"21.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.1","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"25.6","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"5.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.5","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.0","Single Cell Type RNA - Spermatocytes [nTPM]":"20.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"6.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"IFT172","Gene synonym":["BBS20","NPHP17","osm-1","SLB","wim"],"Ensembl":"ENSG00000138002","Gene description":"Intraflagellar transport 172","Uniprot":["Q9UG01"],"Chromosome":"2","Position":"27444377-27489805","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Ciliopathy","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"439.9","Late spermatids":"703.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044893"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044893":"AB_10795009"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.05e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"3.3","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"2.6","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"11.8","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"4.5","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"17.0","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"2.0","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"13.0","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"3.5","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"2.7","Tissue RNA - smooth muscle [nTPM]":"3.8","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"3.5","Tissue RNA - testis [nTPM]":"12.5","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"3.6","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"5.8","Cell RNA - A549 [nTPM]":"5.3","Cell RNA - AF22 [nTPM]":"7.1","Cell RNA - AN3-CA [nTPM]":"10.0","Cell RNA - ASC diff [nTPM]":"12.6","Cell RNA - ASC TERT1 [nTPM]":"10.6","Cell RNA - BEWO [nTPM]":"4.5","Cell RNA - BJ [nTPM]":"5.5","Cell RNA - BJ hTERT+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.5","Cell RNA - CACO-2 [nTPM]":"4.8","Cell RNA - CAPAN-2 [nTPM]":"4.6","Cell RNA - Daudi [nTPM]":"6.3","Cell RNA - EFO-21 [nTPM]":"8.3","Cell RNA - fHDF\/TERT166 [nTPM]":"7.3","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"6.4","Cell RNA - HAP1 [nTPM]":"13.4","Cell RNA - HBEC3-KT [nTPM]":"6.7","Cell RNA - HBF TERT88 [nTPM]":"6.2","Cell RNA - HDLM-2 [nTPM]":"3.1","Cell RNA - HEK 293 [nTPM]":"9.4","Cell RNA - HEL [nTPM]":"16.1","Cell RNA - HeLa [nTPM]":"9.4","Cell RNA - Hep G2 [nTPM]":"5.6","Cell RNA - HHSteC [nTPM]":"7.3","Cell RNA - HL-60 [nTPM]":"7.8","Cell RNA - HMC-1 [nTPM]":"3.4","Cell RNA - HSkMC [nTPM]":"8.6","Cell RNA - hTCEpi [nTPM]":"3.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.3","Cell RNA - hTERT-HME1 [nTPM]":"3.8","Cell RNA - hTERT-RPE1 [nTPM]":"9.0","Cell RNA - HUVEC TERT2 [nTPM]":"10.8","Cell RNA - JURKAT [nTPM]":"7.3","Cell RNA - K-562 [nTPM]":"5.3","Cell RNA - Karpas-707 [nTPM]":"2.2","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"4.5","Cell RNA - MOLT-4 [nTPM]":"4.4","Cell RNA - NB-4 [nTPM]":"3.8","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"4.6","Cell RNA - PC-3 [nTPM]":"5.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"3.5","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"3.7","Cell RNA - SCLC-21H [nTPM]":"5.5","Cell RNA - SH-SY5Y [nTPM]":"8.8","Cell RNA - SiHa [nTPM]":"2.8","Cell RNA - SK-BR-3 [nTPM]":"4.8","Cell RNA - SK-MEL-30 [nTPM]":"9.7","Cell RNA - SuSa [nTPM]":"6.0","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"4.6","Cell RNA - TIME [nTPM]":"11.6","Cell RNA - U-138 MG [nTPM]":"2.9","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"3.7","Cell RNA - U-251 MG [nTPM]":"8.3","Cell RNA - U-266\/70 [nTPM]":"2.8","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"6.7","Cell RNA - U-87 MG [nTPM]":"11.9","Cell RNA - U-937 [nTPM]":"2.3","Cell RNA - WM-115 [nTPM]":"5.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.6","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"3.5","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"5.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.4","Single Cell Type RNA - Astrocytes [nTPM]":"53.5","Single Cell Type RNA - B-cells [nTPM]":"3.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"35.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"32.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"82.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"34.4","Single Cell Type RNA - Early spermatids [nTPM]":"439.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.7","Single Cell Type RNA - Erythroid cells [nTPM]":"7.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"63.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"98.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"5.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"64.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"96.4","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"703.6","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"2.8","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"1.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"104.9","Single Cell Type RNA - Paneth cells [nTPM]":"106.3","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"2.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"142.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"154.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"22.6","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"10.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"75.1","Single Cell Type RNA - Urothelial cells [nTPM]":"39.8"},{"Gene":"IFT43","Gene synonym":["C14orf179","FLJ32173","MGC16028"],"Ensembl":"ENSG00000119650","Gene description":"Intraflagellar transport 43","Uniprot":["Q96FT9"],"Chromosome":"14","Position":"75902136-76084585","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Ectodermal dysplasia","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Respiratory ciliated cells":"305.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003438"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Microtubules"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA003438":"AB_1078327"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.5","Tissue RNA - adrenal gland [nTPM]":"24.0","Tissue RNA - amygdala [nTPM]":"29.2","Tissue RNA - appendix [nTPM]":"12.2","Tissue RNA - basal ganglia [nTPM]":"29.5","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"25.1","Tissue RNA - cerebellum [nTPM]":"28.9","Tissue RNA - cerebral cortex [nTPM]":"31.4","Tissue RNA - cervix [nTPM]":"24.6","Tissue RNA - choroid plexus [nTPM]":"38.7","Tissue RNA - colon [nTPM]":"27.5","Tissue RNA - duodenum [nTPM]":"23.0","Tissue RNA - endometrium 1 [nTPM]":"24.6","Tissue RNA - epididymis [nTPM]":"49.6","Tissue RNA - esophagus [nTPM]":"18.0","Tissue RNA - fallopian tube [nTPM]":"64.5","Tissue RNA - gallbladder [nTPM]":"18.2","Tissue RNA - heart muscle [nTPM]":"43.2","Tissue RNA - hippocampal formation [nTPM]":"28.7","Tissue RNA - hypothalamus [nTPM]":"29.7","Tissue RNA - kidney [nTPM]":"38.9","Tissue RNA - liver [nTPM]":"41.5","Tissue RNA - lung [nTPM]":"20.6","Tissue RNA - lymph node [nTPM]":"11.6","Tissue RNA - medulla oblongata [nTPM]":"29.5","Tissue RNA - midbrain [nTPM]":"31.2","Tissue RNA - ovary [nTPM]":"16.2","Tissue RNA - pancreas [nTPM]":"22.6","Tissue RNA - parathyroid gland [nTPM]":"27.1","Tissue RNA - pituitary gland [nTPM]":"32.8","Tissue RNA - placenta [nTPM]":"21.5","Tissue RNA - pons [nTPM]":"30.9","Tissue RNA - prostate [nTPM]":"26.9","Tissue RNA - rectum [nTPM]":"19.4","Tissue RNA - retina [nTPM]":"25.1","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"30.5","Tissue RNA - skeletal muscle [nTPM]":"13.9","Tissue RNA - skin 1 [nTPM]":"15.4","Tissue RNA - small intestine [nTPM]":"19.3","Tissue RNA - smooth muscle [nTPM]":"27.7","Tissue RNA - spinal cord [nTPM]":"29.8","Tissue RNA - spleen [nTPM]":"15.5","Tissue RNA - stomach 1 [nTPM]":"21.6","Tissue RNA - testis [nTPM]":"40.5","Tissue RNA - thalamus [nTPM]":"29.4","Tissue RNA - thymus [nTPM]":"15.9","Tissue RNA - thyroid gland [nTPM]":"33.0","Tissue RNA - tongue [nTPM]":"8.8","Tissue RNA - tonsil [nTPM]":"17.0","Tissue RNA - urinary bladder [nTPM]":"25.5","Tissue RNA - vagina [nTPM]":"18.4","Tissue RNA - white matter [nTPM]":"29.8","Cell RNA - A-431 [nTPM]":"34.8","Cell RNA - A549 [nTPM]":"38.2","Cell RNA - AF22 [nTPM]":"27.5","Cell RNA - AN3-CA [nTPM]":"42.7","Cell RNA - ASC diff [nTPM]":"33.9","Cell RNA - ASC TERT1 [nTPM]":"54.3","Cell RNA - BEWO [nTPM]":"19.5","Cell RNA - BJ [nTPM]":"22.3","Cell RNA - BJ hTERT+ [nTPM]":"42.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.5","Cell RNA - CACO-2 [nTPM]":"14.6","Cell RNA - CAPAN-2 [nTPM]":"34.9","Cell RNA - Daudi [nTPM]":"3.9","Cell RNA - EFO-21 [nTPM]":"23.8","Cell RNA - fHDF\/TERT166 [nTPM]":"39.5","Cell RNA - GAMG [nTPM]":"30.4","Cell RNA - HaCaT [nTPM]":"36.2","Cell RNA - HAP1 [nTPM]":"26.7","Cell RNA - HBEC3-KT [nTPM]":"41.3","Cell RNA - HBF TERT88 [nTPM]":"37.6","Cell RNA - HDLM-2 [nTPM]":"18.3","Cell RNA - HEK 293 [nTPM]":"25.6","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"22.3","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"94.9","Cell RNA - HL-60 [nTPM]":"3.8","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"48.6","Cell RNA - hTCEpi [nTPM]":"44.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.1","Cell RNA - hTERT-HME1 [nTPM]":"48.3","Cell RNA - hTERT-RPE1 [nTPM]":"48.6","Cell RNA - HUVEC TERT2 [nTPM]":"52.1","Cell RNA - JURKAT [nTPM]":"38.5","Cell RNA - K-562 [nTPM]":"9.6","Cell RNA - Karpas-707 [nTPM]":"15.2","Cell RNA - LHCN-M2 [nTPM]":"40.8","Cell RNA - MCF7 [nTPM]":"69.7","Cell RNA - MOLT-4 [nTPM]":"14.3","Cell RNA - NB-4 [nTPM]":"6.0","Cell RNA - NTERA-2 [nTPM]":"14.2","Cell RNA - OE19 [nTPM]":"42.7","Cell RNA - PC-3 [nTPM]":"48.9","Cell RNA - REH [nTPM]":"9.1","Cell RNA - RH-30 [nTPM]":"22.2","Cell RNA - RPMI-8226 [nTPM]":"10.9","Cell RNA - RPTEC TERT1 [nTPM]":"77.0","Cell RNA - RT4 [nTPM]":"30.0","Cell RNA - SCLC-21H [nTPM]":"26.7","Cell RNA - SH-SY5Y [nTPM]":"31.9","Cell RNA - SiHa [nTPM]":"43.9","Cell RNA - SK-BR-3 [nTPM]":"29.8","Cell RNA - SK-MEL-30 [nTPM]":"31.5","Cell RNA - SuSa [nTPM]":"36.9","Cell RNA - T-47d [nTPM]":"77.4","Cell RNA - THP-1 [nTPM]":"10.2","Cell RNA - TIME [nTPM]":"24.3","Cell RNA - U-138 MG [nTPM]":"19.7","Cell RNA - U-2 OS [nTPM]":"24.7","Cell RNA - U-2197 [nTPM]":"28.9","Cell RNA - U-251 MG [nTPM]":"19.6","Cell RNA - U-266\/70 [nTPM]":"20.1","Cell RNA - U-266\/84 [nTPM]":"18.8","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"76.9","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"20.6","Blood RNA - basophil [nTPM]":"34.5","Blood RNA - classical monocyte [nTPM]":"11.6","Blood RNA - eosinophil [nTPM]":"19.7","Blood RNA - gdT-cell [nTPM]":"13.8","Blood RNA - intermediate monocyte [nTPM]":"16.4","Blood RNA - MAIT T-cell [nTPM]":"17.6","Blood RNA - memory B-cell [nTPM]":"33.8","Blood RNA - memory CD4 T-cell [nTPM]":"14.9","Blood RNA - memory CD8 T-cell [nTPM]":"14.4","Blood RNA - myeloid DC [nTPM]":"15.7","Blood RNA - naive B-cell [nTPM]":"23.1","Blood RNA - naive CD4 T-cell [nTPM]":"24.3","Blood RNA - naive CD8 T-cell [nTPM]":"23.4","Blood RNA - neutrophil [nTPM]":"5.8","Blood RNA - NK-cell [nTPM]":"15.4","Blood RNA - non-classical monocyte [nTPM]":"16.4","Blood RNA - plasmacytoid DC [nTPM]":"20.2","Blood RNA - T-reg [nTPM]":"19.6","Blood RNA - total PBMC [nTPM]":"13.4","Brain RNA - amygdala [nTPM]":"29.2","Brain RNA - basal ganglia [nTPM]":"29.5","Brain RNA - cerebellum [nTPM]":"28.9","Brain RNA - cerebral cortex [nTPM]":"31.4","Brain RNA - hippocampal formation [nTPM]":"28.7","Brain RNA - hypothalamus [nTPM]":"29.7","Brain RNA - medulla oblongata [nTPM]":"29.5","Brain RNA - midbrain [nTPM]":"31.2","Brain RNA - pons [nTPM]":"30.9","Brain RNA - spinal cord [nTPM]":"29.8","Brain RNA - thalamus [nTPM]":"29.4","Brain RNA - white matter [nTPM]":"29.8","Single Cell Type RNA - Adipocytes [nTPM]":"40.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.4","Single Cell Type RNA - Astrocytes [nTPM]":"50.3","Single Cell Type RNA - B-cells [nTPM]":"14.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"103.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"27.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"66.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"64.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.9","Single Cell Type RNA - dendritic cells [nTPM]":"8.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"64.6","Single Cell Type RNA - Ductal cells [nTPM]":"53.8","Single Cell Type RNA - Early spermatids [nTPM]":"147.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"171.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.5","Single Cell Type RNA - Endothelial cells [nTPM]":"35.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.7","Single Cell Type RNA - Erythroid cells [nTPM]":"5.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.7","Single Cell Type RNA - Fibroblasts [nTPM]":"39.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.2","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"28.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"38.6","Single Cell Type RNA - Hepatocytes [nTPM]":"32.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.4","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.2","Single Cell Type RNA - Ionocytes [nTPM]":"61.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.6","Single Cell Type RNA - Langerhans cells [nTPM]":"20.0","Single Cell Type RNA - Late spermatids [nTPM]":"33.2","Single Cell Type RNA - Leydig cells [nTPM]":"33.8","Single Cell Type RNA - Macrophages [nTPM]":"11.5","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"32.0","Single Cell Type RNA - Muller glia cells [nTPM]":"49.8","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"38.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.5","Single Cell Type RNA - Paneth cells [nTPM]":"18.7","Single Cell Type RNA - Peritubular cells [nTPM]":"35.0","Single Cell Type RNA - Plasma cells [nTPM]":"13.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"160.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"305.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"87.7","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"63.5","Single Cell Type RNA - Spermatocytes [nTPM]":"124.4","Single Cell Type RNA - Spermatogonia [nTPM]":"37.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"41.9","Single Cell Type RNA - T-cells [nTPM]":"16.2","Single Cell Type RNA - Theca cells [nTPM]":"32.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.1","Single Cell Type RNA - Urothelial cells [nTPM]":"34.5"},{"Gene":"IGHMBP2","Gene synonym":["CATF1","CMT2S","HCSA","HMN6","SMARD1","SMUBP2","ZFAND7"],"Ensembl":"ENSG00000132740","Gene description":"Immunoglobulin mu DNA binding protein 2","Uniprot":["P38935"],"Chromosome":"11","Position":"68903863-68940602","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Helicase","Hydrolase","Ribonucleoprotein","RNA-binding","tRNA-binding"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"94.6","Late spermatids":"46.9","Spermatocytes":"51.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004092","HPA060994"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA004092":null,"HPA060994":"AB_2684406"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"7.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"7.8","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"6.7","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"6.1","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"2.0","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"15.4","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"4.3","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"6.3","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"5.1","Cell RNA - A549 [nTPM]":"7.3","Cell RNA - AF22 [nTPM]":"4.0","Cell RNA - AN3-CA [nTPM]":"7.4","Cell RNA - ASC diff [nTPM]":"3.6","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"5.2","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.6","Cell RNA - CACO-2 [nTPM]":"14.5","Cell RNA - CAPAN-2 [nTPM]":"7.0","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"9.7","Cell RNA - fHDF\/TERT166 [nTPM]":"3.3","Cell RNA - GAMG [nTPM]":"6.9","Cell RNA - HaCaT [nTPM]":"8.0","Cell RNA - HAP1 [nTPM]":"5.8","Cell RNA - HBEC3-KT [nTPM]":"4.9","Cell RNA - HBF TERT88 [nTPM]":"1.8","Cell RNA - HDLM-2 [nTPM]":"8.3","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"9.6","Cell RNA - Hep G2 [nTPM]":"5.6","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"6.5","Cell RNA - HMC-1 [nTPM]":"7.4","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.2","Cell RNA - hTERT-HME1 [nTPM]":"4.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.5","Cell RNA - HUVEC TERT2 [nTPM]":"4.6","Cell RNA - JURKAT [nTPM]":"11.1","Cell RNA - K-562 [nTPM]":"10.6","Cell RNA - Karpas-707 [nTPM]":"4.6","Cell RNA - LHCN-M2 [nTPM]":"2.3","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"11.1","Cell RNA - NB-4 [nTPM]":"8.9","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"7.9","Cell RNA - PC-3 [nTPM]":"10.3","Cell RNA - REH [nTPM]":"9.4","Cell RNA - RH-30 [nTPM]":"5.7","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.3","Cell RNA - RT4 [nTPM]":"5.9","Cell RNA - SCLC-21H [nTPM]":"8.6","Cell RNA - SH-SY5Y [nTPM]":"5.4","Cell RNA - SiHa [nTPM]":"7.4","Cell RNA - SK-BR-3 [nTPM]":"6.1","Cell RNA - SK-MEL-30 [nTPM]":"16.6","Cell RNA - SuSa [nTPM]":"3.0","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"6.0","Cell RNA - TIME [nTPM]":"6.6","Cell RNA - U-138 MG [nTPM]":"5.3","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"6.6","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"6.3","Cell RNA - U-698 [nTPM]":"6.9","Cell RNA - U-87 MG [nTPM]":"5.3","Cell RNA - U-937 [nTPM]":"6.1","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"6.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"9.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.1","Single Cell Type RNA - Early spermatids [nTPM]":"94.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"6.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.0","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.3","Single Cell Type RNA - Late spermatids [nTPM]":"46.9","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"7.3","Single Cell Type RNA - Muller glia cells [nTPM]":"6.6","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.5","Single Cell Type RNA - Paneth cells [nTPM]":"8.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"5.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.1","Single Cell Type RNA - Spermatocytes [nTPM]":"51.6","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"8.0","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.3"},{"Gene":"ILDR1","Gene synonym":["DFNB42","MGC50831"],"Ensembl":"ENSG00000145103","Gene description":"Immunoglobulin like domain containing receptor 1","Uniprot":["Q86SU0"],"Chromosome":"3","Position":"121987323-122022247","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"15.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"12.8","Club cells":"14.7","Collecting duct cells":"20.2","Cytotrophoblasts":"16.6","Distal enterocytes":"17.5","Glandular and luminal cells":"13.5","Respiratory ciliated cells":"13.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"1.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"6.3","HDLM-2":"8.2","MCF7":"5.1","RT4":"7.5","T-47d":"5.3","U-266\/70":"6.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018207"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018207":"AB_1851742"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.79e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"2.9","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"11.7","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"8.2","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"6.5","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"15.7","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"7.2","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"8.0","Tissue RNA - seminal vesicle [nTPM]":"10.6","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"2.2","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"6.3","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"8.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"2.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"6.1","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"14.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.6","Single Cell Type RNA - Paneth cells [nTPM]":"8.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.5"},{"Gene":"IMPDH1","Gene synonym":["LCA11","RP10","sWSS2608"],"Ensembl":"ENSG00000106348","Gene description":"Inosine monophosphate dehydrogenase 1","Uniprot":["P20839"],"Chromosome":"7","Position":"128392277-128410252","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["GMP biosynthesis","Purine biosynthesis"],"Molecular function":["DNA-binding","Oxidoreductase","RNA-binding"],"Disease involvement":["Disease variant","FDA approved drug targets","Leber congenital amaurosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"106.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"165.8","Cone photoreceptor cells":"141.8","Horizontal cells":"121.1","Rod photoreceptor cells":"205.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"89.1","eosinophil":"89.1","intermediate monocyte":"104.5","myeloid DC":"59.9","neutrophil":"197.5","non-classical monocyte":"135.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"59.9","granulocytes":"197.5","monocytes":"135.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"374.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001400"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":["Rods & Rings"],"Antibody RRID":{"HPA001400":"AB_1079139"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.87e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.31e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.72e-5"},"Tissue RNA - adipose tissue [nTPM]":"54.8","Tissue RNA - adrenal gland [nTPM]":"15.9","Tissue RNA - amygdala [nTPM]":"19.2","Tissue RNA - appendix [nTPM]":"33.8","Tissue RNA - basal ganglia [nTPM]":"18.5","Tissue RNA - bone marrow [nTPM]":"44.1","Tissue RNA - breast [nTPM]":"38.7","Tissue RNA - cerebellum [nTPM]":"15.7","Tissue RNA - cerebral cortex [nTPM]":"23.7","Tissue RNA - cervix [nTPM]":"18.5","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"24.8","Tissue RNA - duodenum [nTPM]":"8.3","Tissue RNA - endometrium 1 [nTPM]":"15.1","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"30.0","Tissue RNA - fallopian tube [nTPM]":"17.7","Tissue RNA - gallbladder [nTPM]":"11.9","Tissue RNA - heart muscle [nTPM]":"23.7","Tissue RNA - hippocampal formation [nTPM]":"18.1","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"15.8","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"31.7","Tissue RNA - lymph node [nTPM]":"25.5","Tissue RNA - medulla oblongata [nTPM]":"26.3","Tissue RNA - midbrain [nTPM]":"18.7","Tissue RNA - ovary [nTPM]":"20.5","Tissue RNA - pancreas [nTPM]":"30.1","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"26.7","Tissue RNA - placenta [nTPM]":"11.4","Tissue RNA - pons [nTPM]":"25.6","Tissue RNA - prostate [nTPM]":"27.8","Tissue RNA - rectum [nTPM]":"9.8","Tissue RNA - retina [nTPM]":"106.2","Tissue RNA - salivary gland [nTPM]":"29.5","Tissue RNA - seminal vesicle [nTPM]":"13.1","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"23.2","Tissue RNA - small intestine [nTPM]":"19.1","Tissue RNA - smooth muscle [nTPM]":"19.6","Tissue RNA - spinal cord [nTPM]":"17.1","Tissue RNA - spleen [nTPM]":"55.9","Tissue RNA - stomach 1 [nTPM]":"48.9","Tissue RNA - testis [nTPM]":"16.5","Tissue RNA - thalamus [nTPM]":"20.0","Tissue RNA - thymus [nTPM]":"8.4","Tissue RNA - thyroid gland [nTPM]":"11.5","Tissue RNA - tongue [nTPM]":"6.2","Tissue RNA - tonsil [nTPM]":"15.9","Tissue RNA - urinary bladder [nTPM]":"29.4","Tissue RNA - vagina [nTPM]":"20.4","Tissue RNA - white matter [nTPM]":"17.1","Cell RNA - A-431 [nTPM]":"111.5","Cell RNA - A549 [nTPM]":"93.2","Cell RNA - AF22 [nTPM]":"13.8","Cell RNA - AN3-CA [nTPM]":"102.8","Cell RNA - ASC diff [nTPM]":"56.5","Cell RNA - ASC TERT1 [nTPM]":"40.7","Cell RNA - BEWO [nTPM]":"38.8","Cell RNA - BJ [nTPM]":"74.1","Cell RNA - BJ hTERT+ [nTPM]":"46.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"61.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.1","Cell RNA - CACO-2 [nTPM]":"68.3","Cell RNA - CAPAN-2 [nTPM]":"35.0","Cell RNA - Daudi [nTPM]":"70.8","Cell RNA - EFO-21 [nTPM]":"24.7","Cell RNA - fHDF\/TERT166 [nTPM]":"111.1","Cell RNA - GAMG [nTPM]":"64.4","Cell RNA - HaCaT [nTPM]":"83.3","Cell RNA - HAP1 [nTPM]":"78.6","Cell RNA - HBEC3-KT [nTPM]":"104.1","Cell RNA - HBF TERT88 [nTPM]":"30.9","Cell RNA - HDLM-2 [nTPM]":"25.8","Cell RNA - HEK 293 [nTPM]":"87.1","Cell RNA - HEL [nTPM]":"46.4","Cell RNA - HeLa [nTPM]":"66.8","Cell RNA - Hep G2 [nTPM]":"49.1","Cell RNA - HHSteC [nTPM]":"51.4","Cell RNA - HL-60 [nTPM]":"62.1","Cell RNA - HMC-1 [nTPM]":"21.1","Cell RNA - HSkMC [nTPM]":"49.4","Cell RNA - hTCEpi [nTPM]":"49.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.2","Cell RNA - hTERT-HME1 [nTPM]":"62.5","Cell RNA - hTERT-RPE1 [nTPM]":"29.2","Cell RNA - HUVEC TERT2 [nTPM]":"74.5","Cell RNA - JURKAT [nTPM]":"42.0","Cell RNA - K-562 [nTPM]":"46.9","Cell RNA - Karpas-707 [nTPM]":"51.8","Cell RNA - LHCN-M2 [nTPM]":"21.0","Cell RNA - MCF7 [nTPM]":"76.1","Cell RNA - MOLT-4 [nTPM]":"44.1","Cell RNA - NB-4 [nTPM]":"164.9","Cell RNA - NTERA-2 [nTPM]":"77.4","Cell RNA - OE19 [nTPM]":"87.7","Cell RNA - PC-3 [nTPM]":"108.0","Cell RNA - REH [nTPM]":"51.9","Cell RNA - RH-30 [nTPM]":"25.2","Cell RNA - RPMI-8226 [nTPM]":"150.8","Cell RNA - RPTEC TERT1 [nTPM]":"27.5","Cell RNA - RT4 [nTPM]":"35.1","Cell RNA - SCLC-21H [nTPM]":"58.3","Cell RNA - SH-SY5Y [nTPM]":"55.6","Cell RNA - SiHa [nTPM]":"48.0","Cell RNA - SK-BR-3 [nTPM]":"374.6","Cell RNA - SK-MEL-30 [nTPM]":"68.3","Cell RNA - SuSa [nTPM]":"8.6","Cell RNA - T-47d [nTPM]":"42.7","Cell RNA - THP-1 [nTPM]":"119.7","Cell RNA - TIME [nTPM]":"68.5","Cell RNA - U-138 MG [nTPM]":"103.6","Cell RNA - U-2 OS [nTPM]":"37.7","Cell RNA - U-2197 [nTPM]":"55.0","Cell RNA - U-251 MG [nTPM]":"53.6","Cell RNA - U-266\/70 [nTPM]":"38.5","Cell RNA - U-266\/84 [nTPM]":"38.3","Cell RNA - U-698 [nTPM]":"90.6","Cell RNA - U-87 MG [nTPM]":"53.0","Cell RNA - U-937 [nTPM]":"134.0","Cell RNA - WM-115 [nTPM]":"64.6","Blood RNA - basophil [nTPM]":"11.2","Blood RNA - classical monocyte [nTPM]":"89.1","Blood RNA - eosinophil [nTPM]":"89.1","Blood RNA - gdT-cell [nTPM]":"22.7","Blood RNA - intermediate monocyte [nTPM]":"104.5","Blood RNA - MAIT T-cell [nTPM]":"24.4","Blood RNA - memory B-cell [nTPM]":"15.5","Blood RNA - memory CD4 T-cell [nTPM]":"17.9","Blood RNA - memory CD8 T-cell [nTPM]":"20.2","Blood RNA - myeloid DC [nTPM]":"59.9","Blood RNA - naive B-cell [nTPM]":"8.9","Blood RNA - naive CD4 T-cell [nTPM]":"10.3","Blood RNA - naive CD8 T-cell [nTPM]":"12.7","Blood RNA - neutrophil [nTPM]":"197.5","Blood RNA - NK-cell [nTPM]":"11.7","Blood RNA - non-classical monocyte [nTPM]":"135.9","Blood RNA - plasmacytoid DC [nTPM]":"6.0","Blood RNA - T-reg [nTPM]":"21.5","Blood RNA - total PBMC [nTPM]":"58.3","Brain RNA - amygdala [nTPM]":"19.2","Brain RNA - basal ganglia [nTPM]":"18.5","Brain RNA - cerebellum [nTPM]":"15.7","Brain RNA - cerebral cortex [nTPM]":"23.7","Brain RNA - hippocampal formation [nTPM]":"18.1","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"26.3","Brain RNA - midbrain [nTPM]":"18.7","Brain RNA - pons [nTPM]":"25.6","Brain RNA - spinal cord [nTPM]":"17.1","Brain RNA - thalamus [nTPM]":"20.0","Brain RNA - white matter [nTPM]":"17.1","Single Cell Type RNA - Adipocytes [nTPM]":"66.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.2","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"13.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"165.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"8.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"141.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - dendritic cells [nTPM]":"11.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"20.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.3","Single Cell Type RNA - Fibroblasts [nTPM]":"15.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.5","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"46.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"46.1","Single Cell Type RNA - Horizontal cells [nTPM]":"121.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.1","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"58.5","Single Cell Type RNA - Langerhans cells [nTPM]":"21.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"38.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"65.3","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.9","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"29.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"205.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"16.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"20.4","Single Cell Type RNA - Theca cells [nTPM]":"18.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.9","Single Cell Type RNA - Urothelial cells [nTPM]":"10.3"},{"Gene":"IMPG1","Gene synonym":["GP147","IPM150","SPACR"],"Ensembl":"ENSG00000112706","Gene description":"Interphotoreceptor matrix proteoglycan 1","Uniprot":["Q17R60"],"Chromosome":"6","Position":"75921114-76072678","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Heparin-binding","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"267","RNA tissue specific nTPM":{"retina":"670.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"673.5","Rod photoreceptor cells":"694.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"1.2"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"3.3"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027142","HPA030332","HPA030333"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027142":"AB_2672132","HPA030332":"AB_2673432","HPA030333":"AB_2673433"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"670.7","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"53.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"673.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"85.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"694.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"IMPG2","Gene synonym":["IPM200","RP56","SPACRCAN"],"Ensembl":"ENSG00000081148","Gene description":"Interphotoreceptor matrix proteoglycan 2","Uniprot":["Q9BZV3"],"Chromosome":"3","Position":"101222546-101320575","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Heparin-binding","Receptor"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"retina":"305.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"517.1","Rod photoreceptor cells":"329.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"ovarian cancer":"2.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008779","HPA015907"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008779":"AB_2668138","HPA015907":"AB_2669323"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"305.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"517.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"23.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"329.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"INF2","Gene synonym":["C14orf151","C14orf173","MGC13251"],"Ensembl":"ENSG00000203485","Gene description":"Inverted formin 2","Uniprot":["Q27J81"],"Chromosome":"14","Position":"104681146-104722535","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"229.3","Gastric mucus-secreting cells":"183.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"PC-3":"100.8"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"224.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000724"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3000000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA000724":"AB_1078325"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.18e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"42.8","Tissue RNA - adrenal gland [nTPM]":"21.4","Tissue RNA - amygdala [nTPM]":"14.0","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"29.6","Tissue RNA - bone marrow [nTPM]":"7.5","Tissue RNA - breast [nTPM]":"35.2","Tissue RNA - cerebellum [nTPM]":"18.3","Tissue RNA - cerebral cortex [nTPM]":"29.5","Tissue RNA - cervix [nTPM]":"28.7","Tissue RNA - choroid plexus [nTPM]":"1.4","Tissue RNA - colon [nTPM]":"40.4","Tissue RNA - duodenum [nTPM]":"21.2","Tissue RNA - endometrium 1 [nTPM]":"24.3","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"20.4","Tissue RNA - fallopian tube [nTPM]":"20.9","Tissue RNA - gallbladder [nTPM]":"8.9","Tissue RNA - heart muscle [nTPM]":"24.1","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"14.7","Tissue RNA - kidney [nTPM]":"27.3","Tissue RNA - liver [nTPM]":"30.2","Tissue RNA - lung [nTPM]":"34.3","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"30.7","Tissue RNA - midbrain [nTPM]":"25.5","Tissue RNA - ovary [nTPM]":"13.6","Tissue RNA - pancreas [nTPM]":"15.7","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"8.3","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"27.5","Tissue RNA - prostate [nTPM]":"23.2","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"17.9","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"13.7","Tissue RNA - skin 1 [nTPM]":"26.9","Tissue RNA - small intestine [nTPM]":"31.7","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"31.4","Tissue RNA - stomach 1 [nTPM]":"34.7","Tissue RNA - testis [nTPM]":"32.2","Tissue RNA - thalamus [nTPM]":"26.3","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"20.8","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"30.2","Tissue RNA - vagina [nTPM]":"28.5","Tissue RNA - white matter [nTPM]":"71.2","Cell RNA - A-431 [nTPM]":"26.3","Cell RNA - A549 [nTPM]":"92.1","Cell RNA - AF22 [nTPM]":"9.9","Cell RNA - AN3-CA [nTPM]":"16.0","Cell RNA - ASC diff [nTPM]":"7.6","Cell RNA - ASC TERT1 [nTPM]":"12.2","Cell RNA - BEWO [nTPM]":"84.2","Cell RNA - BJ [nTPM]":"49.0","Cell RNA - BJ hTERT+ [nTPM]":"14.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.0","Cell RNA - CACO-2 [nTPM]":"35.5","Cell RNA - CAPAN-2 [nTPM]":"40.2","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"46.6","Cell RNA - fHDF\/TERT166 [nTPM]":"17.9","Cell RNA - GAMG [nTPM]":"17.0","Cell RNA - HaCaT [nTPM]":"43.3","Cell RNA - HAP1 [nTPM]":"9.4","Cell RNA - HBEC3-KT [nTPM]":"22.7","Cell RNA - HBF TERT88 [nTPM]":"9.5","Cell RNA - HDLM-2 [nTPM]":"18.5","Cell RNA - HEK 293 [nTPM]":"26.6","Cell RNA - HEL [nTPM]":"22.0","Cell RNA - HeLa [nTPM]":"59.9","Cell RNA - Hep G2 [nTPM]":"23.9","Cell RNA - HHSteC [nTPM]":"16.5","Cell RNA - HL-60 [nTPM]":"6.8","Cell RNA - HMC-1 [nTPM]":"21.0","Cell RNA - HSkMC [nTPM]":"11.4","Cell RNA - hTCEpi [nTPM]":"14.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.8","Cell RNA - hTERT-HME1 [nTPM]":"6.8","Cell RNA - hTERT-RPE1 [nTPM]":"15.0","Cell RNA - HUVEC TERT2 [nTPM]":"24.1","Cell RNA - JURKAT [nTPM]":"9.1","Cell RNA - K-562 [nTPM]":"10.7","Cell RNA - Karpas-707 [nTPM]":"10.5","Cell RNA - LHCN-M2 [nTPM]":"18.0","Cell RNA - MCF7 [nTPM]":"30.0","Cell RNA - MOLT-4 [nTPM]":"10.2","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"17.1","Cell RNA - OE19 [nTPM]":"18.3","Cell RNA - PC-3 [nTPM]":"100.8","Cell RNA - REH [nTPM]":"29.8","Cell RNA - RH-30 [nTPM]":"19.2","Cell RNA - RPMI-8226 [nTPM]":"9.4","Cell RNA - RPTEC TERT1 [nTPM]":"12.6","Cell RNA - RT4 [nTPM]":"38.0","Cell RNA - SCLC-21H [nTPM]":"20.5","Cell RNA - SH-SY5Y [nTPM]":"12.8","Cell RNA - SiHa [nTPM]":"26.4","Cell RNA - SK-BR-3 [nTPM]":"36.7","Cell RNA - SK-MEL-30 [nTPM]":"11.7","Cell RNA - SuSa [nTPM]":"8.0","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"4.9","Cell RNA - TIME [nTPM]":"49.9","Cell RNA - U-138 MG [nTPM]":"29.4","Cell RNA - U-2 OS [nTPM]":"22.1","Cell RNA - U-2197 [nTPM]":"45.7","Cell RNA - U-251 MG [nTPM]":"22.5","Cell RNA - U-266\/70 [nTPM]":"6.9","Cell RNA - U-266\/84 [nTPM]":"3.7","Cell RNA - U-698 [nTPM]":"3.7","Cell RNA - U-87 MG [nTPM]":"41.2","Cell RNA - U-937 [nTPM]":"12.1","Cell RNA - WM-115 [nTPM]":"25.1","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"5.1","Blood RNA - T-reg [nTPM]":"4.0","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"14.0","Brain RNA - basal ganglia [nTPM]":"29.6","Brain RNA - cerebellum [nTPM]":"18.3","Brain RNA - cerebral cortex [nTPM]":"29.5","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"14.7","Brain RNA - medulla oblongata [nTPM]":"30.7","Brain RNA - midbrain [nTPM]":"25.5","Brain RNA - pons [nTPM]":"27.5","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"26.3","Brain RNA - white matter [nTPM]":"71.2","Single Cell Type RNA - Adipocytes [nTPM]":"48.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.4","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"22.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"15.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"54.8","Single Cell Type RNA - dendritic cells [nTPM]":"5.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"229.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"29.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.4","Single Cell Type RNA - Erythroid cells [nTPM]":"17.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"87.8","Single Cell Type RNA - Fibroblasts [nTPM]":"17.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"183.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.2","Single Cell Type RNA - granulocytes [nTPM]":"14.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.4","Single Cell Type RNA - Hepatocytes [nTPM]":"29.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"86.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.8","Single Cell Type RNA - Langerhans cells [nTPM]":"35.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"25.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"14.0","Single Cell Type RNA - Muller glia cells [nTPM]":"55.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"89.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.1","Single Cell Type RNA - Paneth cells [nTPM]":"110.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"7.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"90.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.0","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.6","Single Cell Type RNA - T-cells [nTPM]":"9.3","Single Cell Type RNA - Theca cells [nTPM]":"12.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"66.9","Single Cell Type RNA - Urothelial cells [nTPM]":"38.2"},{"Gene":"ITM2B","Gene synonym":["BRI","BRI2","BRICD2B","E25B","E3-16"],"Ensembl":"ENSG00000136156","Gene description":"Integral membrane protein 2B","Uniprot":["Q9Y287"],"Chromosome":"13","Position":"48232612-48270357","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyloidosis","Deafness","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"4375.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"4375.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"731.2","RPTEC TERT1":"1718.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029292","HPA071992"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5800000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029292":"AB_10601917","HPA071992":"AB_2686480"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.73e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"510.2","Tissue RNA - adrenal gland [nTPM]":"367.4","Tissue RNA - amygdala [nTPM]":"286.9","Tissue RNA - appendix [nTPM]":"172.5","Tissue RNA - basal ganglia [nTPM]":"301.0","Tissue RNA - bone marrow [nTPM]":"125.6","Tissue RNA - breast [nTPM]":"323.8","Tissue RNA - cerebellum [nTPM]":"328.6","Tissue RNA - cerebral cortex [nTPM]":"489.0","Tissue RNA - cervix [nTPM]":"416.1","Tissue RNA - choroid plexus [nTPM]":"406.6","Tissue RNA - colon [nTPM]":"260.1","Tissue RNA - duodenum [nTPM]":"289.2","Tissue RNA - endometrium 1 [nTPM]":"388.8","Tissue RNA - epididymis [nTPM]":"1171.8","Tissue RNA - esophagus [nTPM]":"399.9","Tissue RNA - fallopian tube [nTPM]":"305.4","Tissue RNA - gallbladder [nTPM]":"257.5","Tissue RNA - heart muscle [nTPM]":"381.0","Tissue RNA - hippocampal formation [nTPM]":"320.1","Tissue RNA - hypothalamus [nTPM]":"339.2","Tissue RNA - kidney [nTPM]":"1306.3","Tissue RNA - liver [nTPM]":"391.2","Tissue RNA - lung [nTPM]":"376.1","Tissue RNA - lymph node [nTPM]":"236.7","Tissue RNA - medulla oblongata [nTPM]":"334.9","Tissue RNA - midbrain [nTPM]":"308.0","Tissue RNA - ovary [nTPM]":"507.2","Tissue RNA - pancreas [nTPM]":"179.6","Tissue RNA - parathyroid gland [nTPM]":"233.7","Tissue RNA - pituitary gland [nTPM]":"290.5","Tissue RNA - placenta [nTPM]":"573.8","Tissue RNA - pons [nTPM]":"304.4","Tissue RNA - prostate [nTPM]":"312.5","Tissue RNA - rectum [nTPM]":"191.4","Tissue RNA - retina [nTPM]":"174.4","Tissue RNA - salivary gland [nTPM]":"408.7","Tissue RNA - seminal vesicle [nTPM]":"386.2","Tissue RNA - skeletal muscle [nTPM]":"164.7","Tissue RNA - skin 1 [nTPM]":"399.6","Tissue RNA - small intestine [nTPM]":"287.4","Tissue RNA - smooth muscle [nTPM]":"232.5","Tissue RNA - spinal cord [nTPM]":"373.6","Tissue RNA - spleen [nTPM]":"435.2","Tissue RNA - stomach 1 [nTPM]":"312.8","Tissue RNA - testis [nTPM]":"121.4","Tissue RNA - thalamus [nTPM]":"308.8","Tissue RNA - thymus [nTPM]":"188.3","Tissue RNA - thyroid gland [nTPM]":"386.1","Tissue RNA - tongue [nTPM]":"206.2","Tissue RNA - tonsil [nTPM]":"187.4","Tissue RNA - urinary bladder [nTPM]":"305.1","Tissue RNA - vagina [nTPM]":"402.2","Tissue RNA - white matter [nTPM]":"394.8","Cell RNA - A-431 [nTPM]":"67.6","Cell RNA - A549 [nTPM]":"51.8","Cell RNA - AF22 [nTPM]":"73.1","Cell RNA - AN3-CA [nTPM]":"116.3","Cell RNA - ASC diff [nTPM]":"348.5","Cell RNA - ASC TERT1 [nTPM]":"254.5","Cell RNA - BEWO [nTPM]":"119.2","Cell RNA - BJ [nTPM]":"215.0","Cell RNA - BJ hTERT+ [nTPM]":"202.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"87.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"100.6","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"248.3","Cell RNA - Daudi [nTPM]":"16.6","Cell RNA - EFO-21 [nTPM]":"168.8","Cell RNA - fHDF\/TERT166 [nTPM]":"121.6","Cell RNA - GAMG [nTPM]":"48.5","Cell RNA - HaCaT [nTPM]":"214.1","Cell RNA - HAP1 [nTPM]":"61.3","Cell RNA - HBEC3-KT [nTPM]":"107.0","Cell RNA - HBF TERT88 [nTPM]":"107.4","Cell RNA - HDLM-2 [nTPM]":"69.9","Cell RNA - HEK 293 [nTPM]":"147.3","Cell RNA - HEL [nTPM]":"137.9","Cell RNA - HeLa [nTPM]":"29.0","Cell RNA - Hep G2 [nTPM]":"99.0","Cell RNA - HHSteC [nTPM]":"138.5","Cell RNA - HL-60 [nTPM]":"140.6","Cell RNA - HMC-1 [nTPM]":"731.2","Cell RNA - HSkMC [nTPM]":"113.4","Cell RNA - hTCEpi [nTPM]":"149.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.1","Cell RNA - hTERT-HME1 [nTPM]":"62.0","Cell RNA - hTERT-RPE1 [nTPM]":"375.7","Cell RNA - HUVEC TERT2 [nTPM]":"131.2","Cell RNA - JURKAT [nTPM]":"78.3","Cell RNA - K-562 [nTPM]":"24.5","Cell RNA - Karpas-707 [nTPM]":"90.9","Cell RNA - LHCN-M2 [nTPM]":"174.8","Cell RNA - MCF7 [nTPM]":"29.6","Cell RNA - MOLT-4 [nTPM]":"200.4","Cell RNA - NB-4 [nTPM]":"310.1","Cell RNA - NTERA-2 [nTPM]":"266.0","Cell RNA - OE19 [nTPM]":"116.5","Cell RNA - PC-3 [nTPM]":"103.6","Cell RNA - REH [nTPM]":"100.1","Cell RNA - RH-30 [nTPM]":"100.5","Cell RNA - RPMI-8226 [nTPM]":"73.6","Cell RNA - RPTEC TERT1 [nTPM]":"1718.9","Cell RNA - RT4 [nTPM]":"268.6","Cell RNA - SCLC-21H [nTPM]":"26.2","Cell RNA - SH-SY5Y [nTPM]":"119.5","Cell RNA - SiHa [nTPM]":"154.5","Cell RNA - SK-BR-3 [nTPM]":"110.2","Cell RNA - SK-MEL-30 [nTPM]":"111.0","Cell RNA - SuSa [nTPM]":"306.0","Cell RNA - T-47d [nTPM]":"74.0","Cell RNA - THP-1 [nTPM]":"119.4","Cell RNA - TIME [nTPM]":"180.5","Cell RNA - U-138 MG [nTPM]":"62.9","Cell RNA - U-2 OS [nTPM]":"73.8","Cell RNA - U-2197 [nTPM]":"95.7","Cell RNA - U-251 MG [nTPM]":"85.4","Cell RNA - U-266\/70 [nTPM]":"72.9","Cell RNA - U-266\/84 [nTPM]":"59.6","Cell RNA - U-698 [nTPM]":"2.5","Cell RNA - U-87 MG [nTPM]":"78.0","Cell RNA - U-937 [nTPM]":"75.3","Cell RNA - WM-115 [nTPM]":"155.3","Blood RNA - basophil [nTPM]":"3091.4","Blood RNA - classical monocyte [nTPM]":"864.5","Blood RNA - eosinophil [nTPM]":"2737.9","Blood RNA - gdT-cell [nTPM]":"387.4","Blood RNA - intermediate monocyte [nTPM]":"661.3","Blood RNA - MAIT T-cell [nTPM]":"512.5","Blood RNA - memory B-cell [nTPM]":"235.3","Blood RNA - memory CD4 T-cell [nTPM]":"523.1","Blood RNA - memory CD8 T-cell [nTPM]":"476.4","Blood RNA - myeloid DC [nTPM]":"428.9","Blood RNA - naive B-cell [nTPM]":"245.3","Blood RNA - naive CD4 T-cell [nTPM]":"551.3","Blood RNA - naive CD8 T-cell [nTPM]":"466.8","Blood RNA - neutrophil [nTPM]":"4375.2","Blood RNA - NK-cell [nTPM]":"356.5","Blood RNA - non-classical monocyte [nTPM]":"692.7","Blood RNA - plasmacytoid DC [nTPM]":"196.2","Blood RNA - T-reg [nTPM]":"563.4","Blood RNA - total PBMC [nTPM]":"1723.5","Brain RNA - amygdala [nTPM]":"286.9","Brain RNA - basal ganglia [nTPM]":"301.0","Brain RNA - cerebellum [nTPM]":"328.6","Brain RNA - cerebral cortex [nTPM]":"489.0","Brain RNA - hippocampal formation [nTPM]":"320.1","Brain RNA - hypothalamus [nTPM]":"339.2","Brain RNA - medulla oblongata [nTPM]":"334.9","Brain RNA - midbrain [nTPM]":"308.0","Brain RNA - pons [nTPM]":"304.4","Brain RNA - spinal cord [nTPM]":"373.6","Brain RNA - thalamus [nTPM]":"308.8","Brain RNA - white matter [nTPM]":"394.8","Single Cell Type RNA - Adipocytes [nTPM]":"1380.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"695.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"300.4","Single Cell Type RNA - Astrocytes [nTPM]":"174.6","Single Cell Type RNA - B-cells [nTPM]":"408.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"862.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1661.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2606.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1006.2","Single Cell Type RNA - Bipolar cells [nTPM]":"653.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"460.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"573.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"384.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"722.0","Single Cell Type RNA - Club cells [nTPM]":"1121.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1991.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"187.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1164.3","Single Cell Type RNA - dendritic cells [nTPM]":"448.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"754.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"545.9","Single Cell Type RNA - Ductal cells [nTPM]":"910.2","Single Cell Type RNA - Early spermatids [nTPM]":"23.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"751.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"802.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1166.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"283.3","Single Cell Type RNA - Erythroid cells [nTPM]":"307.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"114.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"682.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2362.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1334.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"302.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1177.2","Single Cell Type RNA - granulocytes [nTPM]":"578.0","Single Cell Type RNA - Granulosa cells [nTPM]":"421.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1319.7","Single Cell Type RNA - Hepatocytes [nTPM]":"557.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2117.8","Single Cell Type RNA - Horizontal cells [nTPM]":"353.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"142.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"503.2","Single Cell Type RNA - Ionocytes [nTPM]":"1129.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1569.8","Single Cell Type RNA - Langerhans cells [nTPM]":"900.6","Single Cell Type RNA - Late spermatids [nTPM]":"76.7","Single Cell Type RNA - Leydig cells [nTPM]":"1867.0","Single Cell Type RNA - Macrophages [nTPM]":"1381.5","Single Cell Type RNA - Melanocytes [nTPM]":"681.3","Single Cell Type RNA - Microglial cells [nTPM]":"252.0","Single Cell Type RNA - monocytes [nTPM]":"1415.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1634.9","Single Cell Type RNA - NK-cells [nTPM]":"425.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"174.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"237.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"515.7","Single Cell Type RNA - Paneth cells [nTPM]":"788.3","Single Cell Type RNA - Peritubular cells [nTPM]":"2011.6","Single Cell Type RNA - Plasma cells [nTPM]":"445.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"922.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1259.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2748.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"795.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"219.4","Single Cell Type RNA - Sertoli cells [nTPM]":"1222.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"602.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1022.9","Single Cell Type RNA - Spermatocytes [nTPM]":"143.6","Single Cell Type RNA - Spermatogonia [nTPM]":"256.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1384.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1149.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1471.5","Single Cell Type RNA - T-cells [nTPM]":"723.2","Single Cell Type RNA - Theca cells [nTPM]":"665.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"440.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1613.4"},{"Gene":"ITPA","Gene synonym":["C20orf37","dJ794I6.3","HLC14-06-P"],"Ensembl":"ENSG00000125877","Gene description":"Inosine triphosphatase","Uniprot":["Q9BY32"],"Chromosome":"20","Position":"3208868-3223870","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Nucleotide metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022824","HPA073963"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA022824":"AB_1851960","HPA073963":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.54e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.2","Tissue RNA - adrenal gland [nTPM]":"37.1","Tissue RNA - amygdala [nTPM]":"16.7","Tissue RNA - appendix [nTPM]":"21.2","Tissue RNA - basal ganglia [nTPM]":"17.5","Tissue RNA - bone marrow [nTPM]":"26.4","Tissue RNA - breast [nTPM]":"25.0","Tissue RNA - cerebellum [nTPM]":"16.9","Tissue RNA - cerebral cortex [nTPM]":"20.0","Tissue RNA - cervix [nTPM]":"24.8","Tissue RNA - choroid plexus [nTPM]":"18.2","Tissue RNA - colon [nTPM]":"25.3","Tissue RNA - duodenum [nTPM]":"27.0","Tissue RNA - endometrium 1 [nTPM]":"24.0","Tissue RNA - epididymis [nTPM]":"13.0","Tissue RNA - esophagus [nTPM]":"43.9","Tissue RNA - fallopian tube [nTPM]":"29.9","Tissue RNA - gallbladder [nTPM]":"16.7","Tissue RNA - heart muscle [nTPM]":"20.8","Tissue RNA - hippocampal formation [nTPM]":"18.2","Tissue RNA - hypothalamus [nTPM]":"16.8","Tissue RNA - kidney [nTPM]":"34.2","Tissue RNA - liver [nTPM]":"28.2","Tissue RNA - lung [nTPM]":"22.4","Tissue RNA - lymph node [nTPM]":"27.6","Tissue RNA - medulla oblongata [nTPM]":"17.0","Tissue RNA - midbrain [nTPM]":"16.5","Tissue RNA - ovary [nTPM]":"21.2","Tissue RNA - pancreas [nTPM]":"21.9","Tissue RNA - parathyroid gland [nTPM]":"24.2","Tissue RNA - pituitary gland [nTPM]":"13.0","Tissue RNA - placenta [nTPM]":"19.8","Tissue RNA - pons [nTPM]":"17.0","Tissue RNA - prostate [nTPM]":"20.3","Tissue RNA - rectum [nTPM]":"19.2","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"26.4","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"26.5","Tissue RNA - skin 1 [nTPM]":"33.6","Tissue RNA - small intestine [nTPM]":"23.2","Tissue RNA - smooth muscle [nTPM]":"18.5","Tissue RNA - spinal cord [nTPM]":"17.3","Tissue RNA - spleen [nTPM]":"27.0","Tissue RNA - stomach 1 [nTPM]":"27.1","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"18.0","Tissue RNA - thymus [nTPM]":"24.8","Tissue RNA - thyroid gland [nTPM]":"33.5","Tissue RNA - tongue [nTPM]":"15.1","Tissue RNA - tonsil [nTPM]":"21.4","Tissue RNA - urinary bladder [nTPM]":"24.1","Tissue RNA - vagina [nTPM]":"25.7","Tissue RNA - white matter [nTPM]":"18.5","Cell RNA - A-431 [nTPM]":"118.2","Cell RNA - A549 [nTPM]":"91.1","Cell RNA - AF22 [nTPM]":"44.0","Cell RNA - AN3-CA [nTPM]":"49.1","Cell RNA - ASC diff [nTPM]":"29.7","Cell RNA - ASC TERT1 [nTPM]":"42.7","Cell RNA - BEWO [nTPM]":"30.9","Cell RNA - BJ [nTPM]":"50.9","Cell RNA - BJ hTERT+ [nTPM]":"72.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.8","Cell RNA - CACO-2 [nTPM]":"75.0","Cell RNA - CAPAN-2 [nTPM]":"106.6","Cell RNA - Daudi [nTPM]":"52.5","Cell RNA - EFO-21 [nTPM]":"46.9","Cell RNA - fHDF\/TERT166 [nTPM]":"48.7","Cell RNA - GAMG [nTPM]":"65.7","Cell RNA - HaCaT [nTPM]":"101.9","Cell RNA - HAP1 [nTPM]":"62.3","Cell RNA - HBEC3-KT [nTPM]":"79.8","Cell RNA - HBF TERT88 [nTPM]":"46.6","Cell RNA - HDLM-2 [nTPM]":"32.9","Cell RNA - HEK 293 [nTPM]":"91.6","Cell RNA - HEL [nTPM]":"123.9","Cell RNA - HeLa [nTPM]":"39.1","Cell RNA - Hep G2 [nTPM]":"117.6","Cell RNA - HHSteC [nTPM]":"55.5","Cell RNA - HL-60 [nTPM]":"54.5","Cell RNA - HMC-1 [nTPM]":"41.4","Cell RNA - HSkMC [nTPM]":"41.5","Cell RNA - hTCEpi [nTPM]":"60.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.4","Cell RNA - hTERT-HME1 [nTPM]":"40.9","Cell RNA - hTERT-RPE1 [nTPM]":"28.6","Cell RNA - HUVEC TERT2 [nTPM]":"52.5","Cell RNA - JURKAT [nTPM]":"39.5","Cell RNA - K-562 [nTPM]":"88.7","Cell RNA - Karpas-707 [nTPM]":"34.2","Cell RNA - LHCN-M2 [nTPM]":"62.6","Cell RNA - MCF7 [nTPM]":"55.2","Cell RNA - MOLT-4 [nTPM]":"66.0","Cell RNA - NB-4 [nTPM]":"156.5","Cell RNA - NTERA-2 [nTPM]":"77.2","Cell RNA - OE19 [nTPM]":"132.1","Cell RNA - PC-3 [nTPM]":"89.6","Cell RNA - REH [nTPM]":"61.4","Cell RNA - RH-30 [nTPM]":"60.7","Cell RNA - RPMI-8226 [nTPM]":"135.0","Cell RNA - RPTEC TERT1 [nTPM]":"96.7","Cell RNA - RT4 [nTPM]":"39.2","Cell RNA - SCLC-21H [nTPM]":"67.4","Cell RNA - SH-SY5Y [nTPM]":"80.9","Cell RNA - SiHa [nTPM]":"41.4","Cell RNA - SK-BR-3 [nTPM]":"154.0","Cell RNA - SK-MEL-30 [nTPM]":"106.3","Cell RNA - SuSa [nTPM]":"19.3","Cell RNA - T-47d [nTPM]":"60.1","Cell RNA - THP-1 [nTPM]":"94.2","Cell RNA - TIME [nTPM]":"37.9","Cell RNA - U-138 MG [nTPM]":"76.5","Cell RNA - U-2 OS [nTPM]":"42.4","Cell RNA - U-2197 [nTPM]":"51.7","Cell RNA - U-251 MG [nTPM]":"116.0","Cell RNA - U-266\/70 [nTPM]":"52.0","Cell RNA - U-266\/84 [nTPM]":"68.4","Cell RNA - U-698 [nTPM]":"94.2","Cell RNA - U-87 MG [nTPM]":"32.9","Cell RNA - U-937 [nTPM]":"102.8","Cell RNA - WM-115 [nTPM]":"83.0","Blood RNA - basophil [nTPM]":"32.8","Blood RNA - classical monocyte [nTPM]":"61.5","Blood RNA - eosinophil [nTPM]":"22.9","Blood RNA - gdT-cell [nTPM]":"47.7","Blood RNA - intermediate monocyte [nTPM]":"78.2","Blood RNA - MAIT T-cell [nTPM]":"41.7","Blood RNA - memory B-cell [nTPM]":"48.9","Blood RNA - memory CD4 T-cell [nTPM]":"43.6","Blood RNA - memory CD8 T-cell [nTPM]":"49.0","Blood RNA - myeloid DC [nTPM]":"74.5","Blood RNA - naive B-cell [nTPM]":"50.2","Blood RNA - naive CD4 T-cell [nTPM]":"32.4","Blood RNA - naive CD8 T-cell [nTPM]":"39.5","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"64.5","Blood RNA - non-classical monocyte [nTPM]":"56.9","Blood RNA - plasmacytoid DC [nTPM]":"70.7","Blood RNA - T-reg [nTPM]":"61.0","Blood RNA - total PBMC [nTPM]":"48.0","Brain RNA - amygdala [nTPM]":"16.7","Brain RNA - basal ganglia [nTPM]":"17.5","Brain RNA - cerebellum [nTPM]":"16.9","Brain RNA - cerebral cortex [nTPM]":"20.0","Brain RNA - hippocampal formation [nTPM]":"18.2","Brain RNA - hypothalamus [nTPM]":"16.8","Brain RNA - medulla oblongata [nTPM]":"17.0","Brain RNA - midbrain [nTPM]":"16.5","Brain RNA - pons [nTPM]":"17.0","Brain RNA - spinal cord [nTPM]":"17.3","Brain RNA - thalamus [nTPM]":"18.0","Brain RNA - white matter [nTPM]":"18.5","Single Cell Type RNA - Adipocytes [nTPM]":"29.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.0","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"38.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"40.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"50.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"93.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"56.9","Single Cell Type RNA - Bipolar cells [nTPM]":"20.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"59.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"74.4","Single Cell Type RNA - dendritic cells [nTPM]":"45.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"104.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"64.4","Single Cell Type RNA - Endothelial cells [nTPM]":"29.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.5","Single Cell Type RNA - Erythroid cells [nTPM]":"24.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"105.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"128.2","Single Cell Type RNA - Fibroblasts [nTPM]":"41.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"48.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.9","Single Cell Type RNA - granulocytes [nTPM]":"42.5","Single Cell Type RNA - Granulosa cells [nTPM]":"49.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.3","Single Cell Type RNA - Hepatocytes [nTPM]":"32.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"116.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"53.1","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"42.4","Single Cell Type RNA - Langerhans cells [nTPM]":"54.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"31.1","Single Cell Type RNA - Macrophages [nTPM]":"49.0","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"90.3","Single Cell Type RNA - Muller glia cells [nTPM]":"21.0","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"102.2","Single Cell Type RNA - Paneth cells [nTPM]":"59.9","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"34.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"53.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"94.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.0","Single Cell Type RNA - Spermatocytes [nTPM]":"16.8","Single Cell Type RNA - Spermatogonia [nTPM]":"17.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"58.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"49.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"56.2","Single Cell Type RNA - T-cells [nTPM]":"47.2","Single Cell Type RNA - Theca cells [nTPM]":"53.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"79.9","Single Cell Type RNA - Urothelial cells [nTPM]":"66.0"},{"Gene":"ITPR1","Gene synonym":["ACV","Insp3r1","IP3R1","PPP1R94","SCA15","SCA16","SCA29"],"Ensembl":"ENSG00000150995","Gene description":"Inositol 1,4,5-trisphosphate receptor type 1","Uniprot":["Q14643"],"Chromosome":"3","Position":"4493345-4847840","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"290.2","Inhibitory neurons":"183.1","Microglial cells":"84.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"49.9"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"13.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"76.4","HEL":"41.1","HeLa":"74.9","HMC-1":"40.0","U-87 MG":"56.7"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"697.2"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"208.8"},"Antibody":["HPA014765","HPA016487"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA014765":"AB_1851843","HPA016487":"AB_1851842"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.6","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"11.8","Tissue RNA - basal ganglia [nTPM]":"12.0","Tissue RNA - bone marrow [nTPM]":"7.2","Tissue RNA - breast [nTPM]":"17.3","Tissue RNA - cerebellum [nTPM]":"49.9","Tissue RNA - cerebral cortex [nTPM]":"20.1","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"19.5","Tissue RNA - duodenum [nTPM]":"4.5","Tissue RNA - endometrium 1 [nTPM]":"36.5","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"10.6","Tissue RNA - fallopian tube [nTPM]":"27.1","Tissue RNA - gallbladder [nTPM]":"14.1","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"13.9","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"11.2","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"25.3","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"45.3","Tissue RNA - pituitary gland [nTPM]":"16.0","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"21.7","Tissue RNA - rectum [nTPM]":"6.3","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"27.9","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"11.5","Tissue RNA - smooth muscle [nTPM]":"24.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"9.2","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"31.7","Tissue RNA - tongue [nTPM]":"5.3","Tissue RNA - tonsil [nTPM]":"10.5","Tissue RNA - urinary bladder [nTPM]":"27.9","Tissue RNA - vagina [nTPM]":"11.8","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"4.1","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"3.0","Cell RNA - ASC diff [nTPM]":"27.7","Cell RNA - ASC TERT1 [nTPM]":"1.9","Cell RNA - BEWO [nTPM]":"11.8","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"1.2","Cell RNA - Daudi [nTPM]":"14.5","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"6.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"2.1","Cell RNA - HDLM-2 [nTPM]":"76.4","Cell RNA - HEK 293 [nTPM]":"3.2","Cell RNA - HEL [nTPM]":"41.1","Cell RNA - HeLa [nTPM]":"74.9","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"27.4","Cell RNA - HL-60 [nTPM]":"17.7","Cell RNA - HMC-1 [nTPM]":"40.0","Cell RNA - HSkMC [nTPM]":"9.2","Cell RNA - hTCEpi [nTPM]":"4.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.8","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"7.6","Cell RNA - HUVEC TERT2 [nTPM]":"7.2","Cell RNA - JURKAT [nTPM]":"8.4","Cell RNA - K-562 [nTPM]":"7.9","Cell RNA - Karpas-707 [nTPM]":"13.9","Cell RNA - LHCN-M2 [nTPM]":"3.7","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"7.2","Cell RNA - NB-4 [nTPM]":"3.0","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"9.7","Cell RNA - REH [nTPM]":"4.2","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"5.5","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"19.5","Cell RNA - SiHa [nTPM]":"5.4","Cell RNA - SK-BR-3 [nTPM]":"4.3","Cell RNA - SK-MEL-30 [nTPM]":"4.3","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"2.6","Cell RNA - THP-1 [nTPM]":"20.6","Cell RNA - TIME [nTPM]":"13.5","Cell RNA - U-138 MG [nTPM]":"1.8","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"3.7","Cell RNA - U-251 MG [nTPM]":"2.3","Cell RNA - U-266\/70 [nTPM]":"17.7","Cell RNA - U-266\/84 [nTPM]":"12.0","Cell RNA - U-698 [nTPM]":"9.6","Cell RNA - U-87 MG [nTPM]":"56.7","Cell RNA - U-937 [nTPM]":"17.0","Cell RNA - WM-115 [nTPM]":"2.7","Blood RNA - basophil [nTPM]":"5.8","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"2.2","Blood RNA - naive B-cell [nTPM]":"13.4","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"4.7","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"12.0","Brain RNA - cerebellum [nTPM]":"49.9","Brain RNA - cerebral cortex [nTPM]":"20.1","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"30.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.4","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"49.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"17.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.4","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.9","Single Cell Type RNA - Endothelial cells [nTPM]":"31.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"290.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"21.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.7","Single Cell Type RNA - granulocytes [nTPM]":"26.5","Single Cell Type RNA - Granulosa cells [nTPM]":"22.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"183.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.9","Single Cell Type RNA - Langerhans cells [nTPM]":"17.4","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"30.1","Single Cell Type RNA - Macrophages [nTPM]":"23.9","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"84.3","Single Cell Type RNA - monocytes [nTPM]":"14.2","Single Cell Type RNA - Muller glia cells [nTPM]":"4.3","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"52.6","Single Cell Type RNA - Plasma cells [nTPM]":"8.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"25.7","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"JAM2","Gene synonym":["C21orf43","CD322","JAM-B","JAMB","VE-JAM"],"Ensembl":"ENSG00000154721","Gene description":"Junctional adhesion molecule 2","Uniprot":["P57087"],"Chromosome":"21","Position":"25639258-25717562","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"63.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"173.8","Astrocytes":"81.6","Endothelial cells":"148.7","Hepatic stellate cells":"112.8","Microglial cells":"82.4","Oligodendrocyte precursor cells":"76.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"27.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"25.5","BJ hTERT+":"16.5","HDLM-2":"16.7","hTERT-RPE1":"22.5","U-138 MG":"18.1","U-87 MG":"13.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028789","HPA077346"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"360000","Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA028789":"AB_2732443","HPA077346":"AB_2732341"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Tissue RNA - adipose tissue [nTPM]":"20.5","Tissue RNA - adrenal gland [nTPM]":"15.8","Tissue RNA - amygdala [nTPM]":"16.6","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"21.5","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"16.8","Tissue RNA - cerebellum [nTPM]":"24.0","Tissue RNA - cerebral cortex [nTPM]":"21.8","Tissue RNA - cervix [nTPM]":"16.8","Tissue RNA - choroid plexus [nTPM]":"12.8","Tissue RNA - colon [nTPM]":"17.8","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"18.5","Tissue RNA - epididymis [nTPM]":"11.2","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"16.1","Tissue RNA - gallbladder [nTPM]":"12.9","Tissue RNA - heart muscle [nTPM]":"19.2","Tissue RNA - hippocampal formation [nTPM]":"19.2","Tissue RNA - hypothalamus [nTPM]":"22.0","Tissue RNA - kidney [nTPM]":"9.2","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"15.5","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"25.9","Tissue RNA - midbrain [nTPM]":"23.1","Tissue RNA - ovary [nTPM]":"16.1","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"8.1","Tissue RNA - placenta [nTPM]":"63.5","Tissue RNA - pons [nTPM]":"21.3","Tissue RNA - prostate [nTPM]":"9.4","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"7.1","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"15.4","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"10.7","Tissue RNA - smooth muscle [nTPM]":"19.6","Tissue RNA - spinal cord [nTPM]":"26.8","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"10.2","Tissue RNA - testis [nTPM]":"17.6","Tissue RNA - thalamus [nTPM]":"25.2","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"10.3","Tissue RNA - tongue [nTPM]":"13.2","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"11.6","Tissue RNA - vagina [nTPM]":"13.2","Tissue RNA - white matter [nTPM]":"23.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"25.5","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.6","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"9.7","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"4.6","Cell RNA - HDLM-2 [nTPM]":"16.7","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"22.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"8.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"3.2","Cell RNA - RH-30 [nTPM]":"5.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"3.7","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"18.1","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"1.8","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"13.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"16.6","Brain RNA - basal ganglia [nTPM]":"21.5","Brain RNA - cerebellum [nTPM]":"24.0","Brain RNA - cerebral cortex [nTPM]":"21.8","Brain RNA - hippocampal formation [nTPM]":"19.2","Brain RNA - hypothalamus [nTPM]":"22.0","Brain RNA - medulla oblongata [nTPM]":"25.9","Brain RNA - midbrain [nTPM]":"23.1","Brain RNA - pons [nTPM]":"21.3","Brain RNA - spinal cord [nTPM]":"26.8","Brain RNA - thalamus [nTPM]":"25.2","Brain RNA - white matter [nTPM]":"23.0","Single Cell Type RNA - Adipocytes [nTPM]":"173.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.3","Single Cell Type RNA - Astrocytes [nTPM]":"81.6","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"16.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.7","Single Cell Type RNA - Endothelial cells [nTPM]":"148.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"28.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"112.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.8","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"15.6","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"2.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"82.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"76.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"24.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.0","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"JAM3","Gene synonym":["JAM-C","JAMC"],"Ensembl":"ENSG00000166086","Gene description":"Junctional adhesion molecule 3","Uniprot":["Q9BX67"],"Chromosome":"11","Position":"134069071-134152001","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Angiogenesis","Cell adhesion","Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"342.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"5.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"5.3","T-cells":"2.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"99.5","RH-30":"122.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003417","HPA050434"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA003417":"AB_1851981","HPA050434":"AB_2681126"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.68e-4"},"Tissue RNA - adipose tissue [nTPM]":"23.6","Tissue RNA - adrenal gland [nTPM]":"18.7","Tissue RNA - amygdala [nTPM]":"53.4","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"86.3","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"19.2","Tissue RNA - cerebellum [nTPM]":"68.7","Tissue RNA - cerebral cortex [nTPM]":"73.4","Tissue RNA - cervix [nTPM]":"33.4","Tissue RNA - choroid plexus [nTPM]":"52.9","Tissue RNA - colon [nTPM]":"54.6","Tissue RNA - duodenum [nTPM]":"6.6","Tissue RNA - endometrium 1 [nTPM]":"40.8","Tissue RNA - epididymis [nTPM]":"17.5","Tissue RNA - esophagus [nTPM]":"21.5","Tissue RNA - fallopian tube [nTPM]":"28.7","Tissue RNA - gallbladder [nTPM]":"24.5","Tissue RNA - heart muscle [nTPM]":"31.0","Tissue RNA - hippocampal formation [nTPM]":"56.5","Tissue RNA - hypothalamus [nTPM]":"61.3","Tissue RNA - kidney [nTPM]":"11.4","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"29.6","Tissue RNA - lymph node [nTPM]":"7.8","Tissue RNA - medulla oblongata [nTPM]":"73.5","Tissue RNA - midbrain [nTPM]":"76.8","Tissue RNA - ovary [nTPM]":"48.7","Tissue RNA - pancreas [nTPM]":"5.1","Tissue RNA - parathyroid gland [nTPM]":"17.7","Tissue RNA - pituitary gland [nTPM]":"33.3","Tissue RNA - placenta [nTPM]":"102.7","Tissue RNA - pons [nTPM]":"71.0","Tissue RNA - prostate [nTPM]":"32.5","Tissue RNA - rectum [nTPM]":"12.9","Tissue RNA - retina [nTPM]":"47.3","Tissue RNA - salivary gland [nTPM]":"13.3","Tissue RNA - seminal vesicle [nTPM]":"44.5","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"13.0","Tissue RNA - small intestine [nTPM]":"22.5","Tissue RNA - smooth muscle [nTPM]":"42.8","Tissue RNA - spinal cord [nTPM]":"59.7","Tissue RNA - spleen [nTPM]":"13.5","Tissue RNA - stomach 1 [nTPM]":"22.4","Tissue RNA - testis [nTPM]":"35.7","Tissue RNA - thalamus [nTPM]":"73.3","Tissue RNA - thymus [nTPM]":"17.6","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"14.6","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"41.7","Tissue RNA - vagina [nTPM]":"23.4","Tissue RNA - white matter [nTPM]":"115.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"87.9","Cell RNA - AN3-CA [nTPM]":"42.5","Cell RNA - ASC diff [nTPM]":"85.3","Cell RNA - ASC TERT1 [nTPM]":"62.7","Cell RNA - BEWO [nTPM]":"75.4","Cell RNA - BJ [nTPM]":"37.0","Cell RNA - BJ hTERT+ [nTPM]":"49.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.8","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"38.7","Cell RNA - fHDF\/TERT166 [nTPM]":"53.3","Cell RNA - GAMG [nTPM]":"56.2","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"70.0","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"28.2","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"29.6","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"6.9","Cell RNA - HHSteC [nTPM]":"24.9","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"36.2","Cell RNA - HSkMC [nTPM]":"43.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.7","Cell RNA - hTERT-HME1 [nTPM]":"9.6","Cell RNA - hTERT-RPE1 [nTPM]":"35.8","Cell RNA - HUVEC TERT2 [nTPM]":"99.5","Cell RNA - JURKAT [nTPM]":"40.8","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"64.5","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"27.5","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"18.9","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"2.9","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"122.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"57.5","Cell RNA - SH-SY5Y [nTPM]":"32.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"1.0","Cell RNA - SuSa [nTPM]":"35.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"25.1","Cell RNA - U-2 OS [nTPM]":"18.4","Cell RNA - U-2197 [nTPM]":"40.3","Cell RNA - U-251 MG [nTPM]":"24.7","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"27.6","Cell RNA - U-937 [nTPM]":"1.2","Cell RNA - WM-115 [nTPM]":"48.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"53.4","Brain RNA - basal ganglia [nTPM]":"86.3","Brain RNA - cerebellum [nTPM]":"68.7","Brain RNA - cerebral cortex [nTPM]":"73.4","Brain RNA - hippocampal formation [nTPM]":"56.5","Brain RNA - hypothalamus [nTPM]":"61.3","Brain RNA - medulla oblongata [nTPM]":"73.5","Brain RNA - midbrain [nTPM]":"76.8","Brain RNA - pons [nTPM]":"71.0","Brain RNA - spinal cord [nTPM]":"59.7","Brain RNA - thalamus [nTPM]":"73.3","Brain RNA - white matter [nTPM]":"115.2","Single Cell Type RNA - Adipocytes [nTPM]":"22.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"10.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"21.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.3","Single Cell Type RNA - Endothelial cells [nTPM]":"35.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"84.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"71.2","Single Cell Type RNA - Fibroblasts [nTPM]":"29.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"44.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"42.9","Single Cell Type RNA - Macrophages [nTPM]":"10.9","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"20.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"76.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"342.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"64.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"75.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.3","Single Cell Type RNA - Spermatocytes [nTPM]":"15.5","Single Cell Type RNA - Spermatogonia [nTPM]":"19.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"3.5","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"JPH1","Gene synonym":["JP-1"],"Ensembl":"ENSG00000104369","Gene description":"Junctophilin 1","Uniprot":["Q9HDC5"],"Chromosome":"8","Position":"74234700-74321540","Protein class":["Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"skeletal muscle":"237.4","tongue":"106.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"38.5","Basal prostatic cells":"32.8","Cardiomyocytes":"35.7","Excitatory neurons":"82.2","Inhibitory neurons":"50.3","Prostatic glandular cells":"32.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MOLT-4":"15.1","OE19":"17.7","SK-BR-3":"34.4","T-47d":"24.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008996","HPA009413","CAB013461"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB013461":null,"HPA008996":"AB_1852023","HPA009413":"AB_1079163"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.77e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"7.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"7.6","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"13.2","Tissue RNA - colon [nTPM]":"3.3","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"3.7","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"2.8","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"237.4","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"106.0","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"4.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"6.4","Cell RNA - HAP1 [nTPM]":"5.6","Cell RNA - HBEC3-KT [nTPM]":"4.3","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"8.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"3.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"4.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"4.1","Cell RNA - MOLT-4 [nTPM]":"15.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"9.7","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"2.9","Cell RNA - REH [nTPM]":"7.6","Cell RNA - RH-30 [nTPM]":"5.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"12.7","Cell RNA - SCLC-21H [nTPM]":"7.3","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"34.4","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"24.2","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.6","Cell RNA - U-2 OS [nTPM]":"2.3","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"1.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"7.5","Brain RNA - cerebellum [nTPM]":"7.6","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"82.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.7","Single Cell Type RNA - Urothelial cells [nTPM]":"25.6"},{"Gene":"JPH3","Gene synonym":["CAGL237","HDL2","JP-3","JP3","TNRC22"],"Ensembl":"ENSG00000154118","Gene description":"Junctophilin 3","Uniprot":["Q8WXH2"],"Chromosome":"16","Position":"87601835-87698156","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"59.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"24.4","Cone photoreceptor cells":"22.9","Early spermatids":"41.1","Excitatory neurons":"33.2","Horizontal cells":"50.5","Inhibitory neurons":"28.7","Late spermatids":"14.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.7"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"amygdala":"17.1","basal ganglia":"24.6","cerebral cortex":"59.1","hippocampal formation":"42.7","white matter":"20.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"6.5","NTERA-2":"5.7","SH-SY5Y":"7.2","SiHa":"5.0","U-2 OS":"22.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076304"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA076304":"AB_2686793"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"17.1","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"24.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"59.1","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"42.7","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"14.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"20.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"3.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"6.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"5.7","Cell RNA - OE19 [nTPM]":"1.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"5.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"22.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"17.1","Brain RNA - basal ganglia [nTPM]":"24.6","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"59.1","Brain RNA - hippocampal formation [nTPM]":"42.7","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"20.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"24.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"41.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"14.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KANK1","Gene synonym":["ANKRD15","KANK","KIAA0172"],"Ensembl":"ENSG00000107104","Gene description":"KN motif and ankyrin repeat domains 1","Uniprot":["Q14678"],"Chromosome":"9","Position":"470291-746106","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"355.5","Late spermatids":"228.7","Oligodendrocyte precursor cells":"322.7","Oligodendrocytes":"191.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"4.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"B-cells":"1.1","dendritic cells":"4.0","T-cells":"2.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"96.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005539","HPA056090"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA005539":"AB_1078164","HPA056090":"AB_2683034"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Tissue RNA - adipose tissue [nTPM]":"42.6","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"49.0","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"52.7","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"31.2","Tissue RNA - cerebellum [nTPM]":"42.3","Tissue RNA - cerebral cortex [nTPM]":"47.5","Tissue RNA - cervix [nTPM]":"40.9","Tissue RNA - choroid plexus [nTPM]":"61.8","Tissue RNA - colon [nTPM]":"49.2","Tissue RNA - duodenum [nTPM]":"12.1","Tissue RNA - endometrium 1 [nTPM]":"62.2","Tissue RNA - epididymis [nTPM]":"13.0","Tissue RNA - esophagus [nTPM]":"64.6","Tissue RNA - fallopian tube [nTPM]":"31.7","Tissue RNA - gallbladder [nTPM]":"15.2","Tissue RNA - heart muscle [nTPM]":"88.2","Tissue RNA - hippocampal formation [nTPM]":"45.1","Tissue RNA - hypothalamus [nTPM]":"44.9","Tissue RNA - kidney [nTPM]":"31.6","Tissue RNA - liver [nTPM]":"101.9","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"51.6","Tissue RNA - midbrain [nTPM]":"44.9","Tissue RNA - ovary [nTPM]":"22.1","Tissue RNA - pancreas [nTPM]":"28.3","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"27.9","Tissue RNA - placenta [nTPM]":"25.8","Tissue RNA - pons [nTPM]":"48.3","Tissue RNA - prostate [nTPM]":"42.5","Tissue RNA - rectum [nTPM]":"14.9","Tissue RNA - retina [nTPM]":"11.0","Tissue RNA - salivary gland [nTPM]":"29.9","Tissue RNA - seminal vesicle [nTPM]":"31.8","Tissue RNA - skeletal muscle [nTPM]":"66.4","Tissue RNA - skin 1 [nTPM]":"51.8","Tissue RNA - small intestine [nTPM]":"23.6","Tissue RNA - smooth muscle [nTPM]":"37.4","Tissue RNA - spinal cord [nTPM]":"47.6","Tissue RNA - spleen [nTPM]":"6.9","Tissue RNA - stomach 1 [nTPM]":"25.9","Tissue RNA - testis [nTPM]":"15.4","Tissue RNA - thalamus [nTPM]":"48.4","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"30.8","Tissue RNA - tongue [nTPM]":"39.9","Tissue RNA - tonsil [nTPM]":"11.8","Tissue RNA - urinary bladder [nTPM]":"70.1","Tissue RNA - vagina [nTPM]":"52.3","Tissue RNA - white matter [nTPM]":"48.9","Cell RNA - A-431 [nTPM]":"5.9","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"4.0","Cell RNA - AN3-CA [nTPM]":"72.0","Cell RNA - ASC diff [nTPM]":"57.8","Cell RNA - ASC TERT1 [nTPM]":"21.9","Cell RNA - BEWO [nTPM]":"19.9","Cell RNA - BJ [nTPM]":"37.1","Cell RNA - BJ hTERT+ [nTPM]":"25.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.7","Cell RNA - CACO-2 [nTPM]":"30.2","Cell RNA - CAPAN-2 [nTPM]":"2.5","Cell RNA - Daudi [nTPM]":"46.2","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"46.0","Cell RNA - GAMG [nTPM]":"7.0","Cell RNA - HaCaT [nTPM]":"12.3","Cell RNA - HAP1 [nTPM]":"15.7","Cell RNA - HBEC3-KT [nTPM]":"30.4","Cell RNA - HBF TERT88 [nTPM]":"5.3","Cell RNA - HDLM-2 [nTPM]":"22.7","Cell RNA - HEK 293 [nTPM]":"8.3","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"17.0","Cell RNA - Hep G2 [nTPM]":"96.0","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"11.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"12.6","Cell RNA - hTCEpi [nTPM]":"41.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.2","Cell RNA - hTERT-HME1 [nTPM]":"35.6","Cell RNA - hTERT-RPE1 [nTPM]":"13.2","Cell RNA - HUVEC TERT2 [nTPM]":"31.2","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"56.4","Cell RNA - LHCN-M2 [nTPM]":"23.1","Cell RNA - MCF7 [nTPM]":"14.4","Cell RNA - MOLT-4 [nTPM]":"4.5","Cell RNA - NB-4 [nTPM]":"46.9","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"8.9","Cell RNA - PC-3 [nTPM]":"9.0","Cell RNA - REH [nTPM]":"1.7","Cell RNA - RH-30 [nTPM]":"7.9","Cell RNA - RPMI-8226 [nTPM]":"8.6","Cell RNA - RPTEC TERT1 [nTPM]":"24.5","Cell RNA - RT4 [nTPM]":"36.1","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"3.6","Cell RNA - SK-BR-3 [nTPM]":"10.9","Cell RNA - SK-MEL-30 [nTPM]":"50.9","Cell RNA - SuSa [nTPM]":"33.3","Cell RNA - T-47d [nTPM]":"7.1","Cell RNA - THP-1 [nTPM]":"8.7","Cell RNA - TIME [nTPM]":"46.1","Cell RNA - U-138 MG [nTPM]":"8.4","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"10.8","Cell RNA - U-251 MG [nTPM]":"17.1","Cell RNA - U-266\/70 [nTPM]":"9.8","Cell RNA - U-266\/84 [nTPM]":"61.9","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"5.6","Cell RNA - U-937 [nTPM]":"21.1","Cell RNA - WM-115 [nTPM]":"15.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"49.0","Brain RNA - basal ganglia [nTPM]":"52.7","Brain RNA - cerebellum [nTPM]":"42.3","Brain RNA - cerebral cortex [nTPM]":"47.5","Brain RNA - hippocampal formation [nTPM]":"45.1","Brain RNA - hypothalamus [nTPM]":"44.9","Brain RNA - medulla oblongata [nTPM]":"51.6","Brain RNA - midbrain [nTPM]":"44.9","Brain RNA - pons [nTPM]":"48.3","Brain RNA - spinal cord [nTPM]":"47.6","Brain RNA - thalamus [nTPM]":"48.4","Brain RNA - white matter [nTPM]":"48.9","Single Cell Type RNA - Adipocytes [nTPM]":"18.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.2","Single Cell Type RNA - Astrocytes [nTPM]":"355.5","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"102.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"37.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"94.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"89.2","Single Cell Type RNA - dendritic cells [nTPM]":"15.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.6","Single Cell Type RNA - Early spermatids [nTPM]":"102.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.4","Single Cell Type RNA - Endothelial cells [nTPM]":"21.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.8","Single Cell Type RNA - Fibroblasts [nTPM]":"21.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"38.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"70.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.9","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"228.7","Single Cell Type RNA - Leydig cells [nTPM]":"32.3","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"60.9","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"6.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"322.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"191.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.5","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"10.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"129.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.0","Single Cell Type RNA - Spermatocytes [nTPM]":"28.4","Single Cell Type RNA - Spermatogonia [nTPM]":"25.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.2","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.0","Single Cell Type RNA - Urothelial cells [nTPM]":"63.6"},{"Gene":"KARS1","Gene synonym":["DFNB89","KARS","KARS2"],"Ensembl":"ENSG00000065427","Gene description":"Lysyl-tRNA synthetase 1","Uniprot":["Q15046"],"Chromosome":"16","Position":"75627474-75648643","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Disease variant","Neurodegeneration","Neuropathy","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cardiomyocytes":"90.7","Cytotrophoblasts":"122.7","Extravillous trophoblasts":"143.3","Hofbauer cells":"89.5","Syncytiotrophoblasts":"110.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041345","HPA041550"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"82000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA041345":"AB_10795589","HPA041550":"AB_10794520"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.84e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"68.5","Tissue RNA - adrenal gland [nTPM]":"49.6","Tissue RNA - amygdala [nTPM]":"45.5","Tissue RNA - appendix [nTPM]":"71.6","Tissue RNA - basal ganglia [nTPM]":"47.3","Tissue RNA - bone marrow [nTPM]":"86.1","Tissue RNA - breast [nTPM]":"83.0","Tissue RNA - cerebellum [nTPM]":"46.9","Tissue RNA - cerebral cortex [nTPM]":"63.2","Tissue RNA - cervix [nTPM]":"60.3","Tissue RNA - choroid plexus [nTPM]":"50.6","Tissue RNA - colon [nTPM]":"75.8","Tissue RNA - duodenum [nTPM]":"62.4","Tissue RNA - endometrium 1 [nTPM]":"53.9","Tissue RNA - epididymis [nTPM]":"75.1","Tissue RNA - esophagus [nTPM]":"72.5","Tissue RNA - fallopian tube [nTPM]":"69.5","Tissue RNA - gallbladder [nTPM]":"50.4","Tissue RNA - heart muscle [nTPM]":"96.0","Tissue RNA - hippocampal formation [nTPM]":"45.6","Tissue RNA - hypothalamus [nTPM]":"48.3","Tissue RNA - kidney [nTPM]":"72.2","Tissue RNA - liver [nTPM]":"76.8","Tissue RNA - lung [nTPM]":"53.1","Tissue RNA - lymph node [nTPM]":"88.3","Tissue RNA - medulla oblongata [nTPM]":"46.9","Tissue RNA - midbrain [nTPM]":"47.5","Tissue RNA - ovary [nTPM]":"74.9","Tissue RNA - pancreas [nTPM]":"86.5","Tissue RNA - parathyroid gland [nTPM]":"76.7","Tissue RNA - pituitary gland [nTPM]":"51.5","Tissue RNA - placenta [nTPM]":"62.2","Tissue RNA - pons [nTPM]":"46.8","Tissue RNA - prostate [nTPM]":"55.2","Tissue RNA - rectum [nTPM]":"85.6","Tissue RNA - retina [nTPM]":"69.6","Tissue RNA - salivary gland [nTPM]":"79.6","Tissue RNA - seminal vesicle [nTPM]":"60.6","Tissue RNA - skeletal muscle [nTPM]":"213.4","Tissue RNA - skin 1 [nTPM]":"67.3","Tissue RNA - small intestine [nTPM]":"62.6","Tissue RNA - smooth muscle [nTPM]":"69.6","Tissue RNA - spinal cord [nTPM]":"46.8","Tissue RNA - spleen [nTPM]":"57.6","Tissue RNA - stomach 1 [nTPM]":"66.2","Tissue RNA - testis [nTPM]":"98.9","Tissue RNA - thalamus [nTPM]":"47.4","Tissue RNA - thymus [nTPM]":"96.6","Tissue RNA - thyroid gland [nTPM]":"65.3","Tissue RNA - tongue [nTPM]":"186.8","Tissue RNA - tonsil [nTPM]":"107.8","Tissue RNA - urinary bladder [nTPM]":"92.1","Tissue RNA - vagina [nTPM]":"55.0","Tissue RNA - white matter [nTPM]":"48.1","Cell RNA - A-431 [nTPM]":"164.2","Cell RNA - A549 [nTPM]":"187.0","Cell RNA - AF22 [nTPM]":"133.5","Cell RNA - AN3-CA [nTPM]":"185.4","Cell RNA - ASC diff [nTPM]":"140.1","Cell RNA - ASC TERT1 [nTPM]":"140.3","Cell RNA - BEWO [nTPM]":"262.4","Cell RNA - BJ [nTPM]":"135.0","Cell RNA - BJ hTERT+ [nTPM]":"164.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"290.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"217.0","Cell RNA - CACO-2 [nTPM]":"332.8","Cell RNA - CAPAN-2 [nTPM]":"209.0","Cell RNA - Daudi [nTPM]":"292.4","Cell RNA - EFO-21 [nTPM]":"145.4","Cell RNA - fHDF\/TERT166 [nTPM]":"180.8","Cell RNA - GAMG [nTPM]":"138.4","Cell RNA - HaCaT [nTPM]":"229.4","Cell RNA - HAP1 [nTPM]":"272.0","Cell RNA - HBEC3-KT [nTPM]":"246.7","Cell RNA - HBF TERT88 [nTPM]":"314.4","Cell RNA - HDLM-2 [nTPM]":"86.0","Cell RNA - HEK 293 [nTPM]":"139.8","Cell RNA - HEL [nTPM]":"161.4","Cell RNA - HeLa [nTPM]":"153.1","Cell RNA - Hep G2 [nTPM]":"348.5","Cell RNA - HHSteC [nTPM]":"255.8","Cell RNA - HL-60 [nTPM]":"245.5","Cell RNA - HMC-1 [nTPM]":"174.1","Cell RNA - HSkMC [nTPM]":"166.4","Cell RNA - hTCEpi [nTPM]":"173.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"257.4","Cell RNA - hTERT-HME1 [nTPM]":"414.6","Cell RNA - hTERT-RPE1 [nTPM]":"147.7","Cell RNA - HUVEC TERT2 [nTPM]":"240.0","Cell RNA - JURKAT [nTPM]":"253.5","Cell RNA - K-562 [nTPM]":"273.4","Cell RNA - Karpas-707 [nTPM]":"68.5","Cell RNA - LHCN-M2 [nTPM]":"222.5","Cell RNA - MCF7 [nTPM]":"378.0","Cell RNA - MOLT-4 [nTPM]":"254.1","Cell RNA - NB-4 [nTPM]":"262.2","Cell RNA - NTERA-2 [nTPM]":"284.3","Cell RNA - OE19 [nTPM]":"238.4","Cell RNA - PC-3 [nTPM]":"135.9","Cell RNA - REH [nTPM]":"329.2","Cell RNA - RH-30 [nTPM]":"120.0","Cell RNA - RPMI-8226 [nTPM]":"358.4","Cell RNA - RPTEC TERT1 [nTPM]":"235.4","Cell RNA - RT4 [nTPM]":"136.3","Cell RNA - SCLC-21H [nTPM]":"200.2","Cell RNA - SH-SY5Y [nTPM]":"162.9","Cell RNA - SiHa [nTPM]":"339.5","Cell RNA - SK-BR-3 [nTPM]":"122.8","Cell RNA - SK-MEL-30 [nTPM]":"152.2","Cell RNA - SuSa [nTPM]":"144.8","Cell RNA - T-47d [nTPM]":"166.1","Cell RNA - THP-1 [nTPM]":"229.2","Cell RNA - TIME [nTPM]":"133.8","Cell RNA - U-138 MG [nTPM]":"159.8","Cell RNA - U-2 OS [nTPM]":"164.9","Cell RNA - U-2197 [nTPM]":"123.6","Cell RNA - U-251 MG [nTPM]":"196.7","Cell RNA - U-266\/70 [nTPM]":"145.1","Cell RNA - U-266\/84 [nTPM]":"178.6","Cell RNA - U-698 [nTPM]":"696.6","Cell RNA - U-87 MG [nTPM]":"139.5","Cell RNA - U-937 [nTPM]":"206.5","Cell RNA - WM-115 [nTPM]":"199.7","Blood RNA - basophil [nTPM]":"88.6","Blood RNA - classical monocyte [nTPM]":"112.7","Blood RNA - eosinophil [nTPM]":"130.0","Blood RNA - gdT-cell [nTPM]":"110.7","Blood RNA - intermediate monocyte [nTPM]":"155.7","Blood RNA - MAIT T-cell [nTPM]":"202.6","Blood RNA - memory B-cell [nTPM]":"109.5","Blood RNA - memory CD4 T-cell [nTPM]":"137.1","Blood RNA - memory CD8 T-cell [nTPM]":"132.0","Blood RNA - myeloid DC [nTPM]":"135.7","Blood RNA - naive B-cell [nTPM]":"91.6","Blood RNA - naive CD4 T-cell [nTPM]":"126.6","Blood RNA - naive CD8 T-cell [nTPM]":"117.1","Blood RNA - neutrophil [nTPM]":"24.9","Blood RNA - NK-cell [nTPM]":"127.6","Blood RNA - non-classical monocyte [nTPM]":"163.1","Blood RNA - plasmacytoid DC [nTPM]":"85.7","Blood RNA - T-reg [nTPM]":"155.5","Blood RNA - total PBMC [nTPM]":"160.5","Brain RNA - amygdala [nTPM]":"45.5","Brain RNA - basal ganglia [nTPM]":"47.3","Brain RNA - cerebellum [nTPM]":"46.9","Brain RNA - cerebral cortex [nTPM]":"63.2","Brain RNA - hippocampal formation [nTPM]":"45.6","Brain RNA - hypothalamus [nTPM]":"48.3","Brain RNA - medulla oblongata [nTPM]":"46.9","Brain RNA - midbrain [nTPM]":"47.5","Brain RNA - pons [nTPM]":"46.8","Brain RNA - spinal cord [nTPM]":"46.8","Brain RNA - thalamus [nTPM]":"47.4","Brain RNA - white matter [nTPM]":"48.1","Single Cell Type RNA - Adipocytes [nTPM]":"14.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"90.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"122.7","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"143.3","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"89.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"110.0","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNA1","Gene synonym":["AEMK","HUK1","Kv1.1","MBK1","RBK1"],"Ensembl":"ENSG00000111262","Gene description":"Potassium voltage-gated channel subfamily A member 1","Uniprot":["Q09470"],"Chromosome":"12","Position":"4909905-4918256","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"50.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Bipolar cells":"15.1","Excitatory neurons":"39.6","Inhibitory neurons":"18.6","Oligodendrocyte precursor cells":"16.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"1.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074471"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074471":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-4"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"10.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"22.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"27.6","Tissue RNA - cerebral cortex [nTPM]":"50.1","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"3.9","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"21.0","Tissue RNA - hypothalamus [nTPM]":"7.9","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"24.9","Tissue RNA - midbrain [nTPM]":"10.7","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"25.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"24.3","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"28.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"10.6","Brain RNA - basal ganglia [nTPM]":"22.5","Brain RNA - cerebellum [nTPM]":"27.6","Brain RNA - cerebral cortex [nTPM]":"50.1","Brain RNA - hippocampal formation [nTPM]":"21.0","Brain RNA - hypothalamus [nTPM]":"7.9","Brain RNA - medulla oblongata [nTPM]":"24.9","Brain RNA - midbrain [nTPM]":"10.7","Brain RNA - pons [nTPM]":"25.2","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"24.3","Brain RNA - white matter [nTPM]":"28.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNA2","Gene synonym":["HK4","Kv1.2"],"Ensembl":"ENSG00000177301","Gene description":"Potassium voltage-gated channel subfamily A member 2","Uniprot":["P16389"],"Chromosome":"1","Position":"110519837-110631474","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"81.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"49.9","Excitatory neurons":"36.7","Inhibitory neurons":"37.1","Muller glia cells":"19.8","Oligodendrocyte precursor cells":"36.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.2","testis cancer":"1.0"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"81.3"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"T-cells":"1.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"4.8","SCLC-21H":"1.4","U-2 OS":"1.2","U-266\/70":"1.9","U-266\/84":"3.1","WM-115":"1.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001976"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001976":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"11.1","Tissue RNA - cerebral cortex [nTPM]":"81.3","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"12.5","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"28.0","Tissue RNA - midbrain [nTPM]":"7.5","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"32.0","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"27.1","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"20.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.9","Cell RNA - U-266\/84 [nTPM]":"3.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"11.1","Brain RNA - cerebral cortex [nTPM]":"81.3","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"12.5","Brain RNA - medulla oblongata [nTPM]":"28.0","Brain RNA - midbrain [nTPM]":"7.5","Brain RNA - pons [nTPM]":"32.0","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"27.1","Brain RNA - white matter [nTPM]":"20.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"49.9","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"7.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"19.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNB1","Gene synonym":["Kv2.1"],"Ensembl":"ENSG00000158445","Gene description":"Potassium voltage-gated channel subfamily B member 1","Uniprot":["Q14721"],"Chromosome":"20","Position":"49293394-49484297","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Exocytosis","Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"retina":"113.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"115.6","Cone photoreceptor cells":"212.7","Excitatory neurons":"150.6","Inhibitory neurons":"89.9","Rod photoreceptor cells":"386.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"17.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1.4","CACO-2":"2.2","HL-60":"1.1","hTCEpi":"1.2","U-2 OS":"1.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001979","HPA042434"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001979":null,"HPA042434":"AB_2677996"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-4"},"Tissue RNA - adipose tissue [nTPM]":"10.7","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"6.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"17.8","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"6.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"6.0","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.2","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"113.3","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"7.3","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"2.0","Tissue RNA - smooth muscle [nTPM]":"5.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"4.4","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"7.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.4","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"1.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"6.6","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"17.8","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"7.9","Single Cell Type RNA - Adipocytes [nTPM]":"20.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"115.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"212.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.9","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"150.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"89.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"38.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"43.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"34.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"386.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KCNC1","Gene synonym":["Kv3.1"],"Ensembl":"ENSG00000129159","Gene description":"Potassium voltage-gated channel subfamily C member 1","Uniprot":["P48547"],"Chromosome":"11","Position":"17734774-17856804","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"47.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"79.6","Excitatory neurons":"48.2","Inhibitory neurons":"120.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.1","testis cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"3.2","neutrophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"3.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"1.6","RH-30":"3.7","SCLC-21H":"3.5","SH-SY5Y":"2.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047634","HPA048249"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA047634":"AB_2680109","HPA048249":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"3.3","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"41.0","Tissue RNA - cerebral cortex [nTPM]":"47.3","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"8.8","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"9.3","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"7.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"12.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"18.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"1.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"3.5","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"3.3","Brain RNA - cerebellum [nTPM]":"41.0","Brain RNA - cerebral cortex [nTPM]":"47.3","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"8.8","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"9.3","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"12.3","Brain RNA - white matter [nTPM]":"18.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"79.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"9.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"120.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.1","Single Cell Type RNA - Spermatogonia [nTPM]":"5.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"1.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNC3","Gene synonym":["Kv3.3","SCA13"],"Ensembl":"ENSG00000131398","Gene description":"Potassium voltage-gated channel subfamily C member 3","Uniprot":["Q14003"],"Chromosome":"19","Position":"50311937-50333515","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"75.8","thyroid gland":"52.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"20.2","Endometrial ciliated cells":"23.9","Excitatory neurons":"15.6","Glandular and luminal cells":"16.3","Inhibitory neurons":"18.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"75.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"7.7","CAPAN-2":"7.2","HDLM-2":"7.0","HMC-1":"20.3","K-562":"7.0","SK-BR-3":"14.0","T-47d":"12.0","U-2 OS":"8.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018041"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018041":"AB_1855579"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"3.5","Tissue RNA - cerebellum [nTPM]":"17.3","Tissue RNA - cerebral cortex [nTPM]":"75.8","Tissue RNA - cervix [nTPM]":"6.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"23.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"17.8","Tissue RNA - liver [nTPM]":"4.4","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"2.6","Tissue RNA - medulla oblongata [nTPM]":"20.0","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"14.1","Tissue RNA - pituitary gland [nTPM]":"21.1","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"8.0","Tissue RNA - salivary gland [nTPM]":"3.0","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"3.3","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"15.0","Tissue RNA - thymus [nTPM]":"2.5","Tissue RNA - thyroid gland [nTPM]":"52.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"20.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.8","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"7.7","Cell RNA - CAPAN-2 [nTPM]":"7.2","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"7.0","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"2.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"20.3","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.7","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"3.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"1.7","Cell RNA - SK-BR-3 [nTPM]":"14.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"12.0","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"8.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"1.9","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"17.3","Brain RNA - cerebral cortex [nTPM]":"75.8","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"20.0","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"15.0","Brain RNA - white matter [nTPM]":"20.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"8.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"KCND3","Gene synonym":["KSHIVB","Kv4.3","SCA19","SCA22"],"Ensembl":"ENSG00000171385","Gene description":"Potassium voltage-gated channel subfamily D member 3","Uniprot":["Q9UK17"],"Chromosome":"1","Position":"111770662-111989668","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Brugada syndrome","Disease variant","FDA approved drug targets","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"46.8","Cardiomyocytes":"38.1","Excitatory neurons":"105.7","Hepatocytes":"37.8","Inhibitory neurons":"88.4","Oligodendrocyte precursor cells":"45.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"8.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"4.8","SCLC-21H":"10.1","U-2 OS":"1.6","WM-115":"2.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029452"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029452":"AB_10602239"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"17.0","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"13.8","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"18.1","Tissue RNA - cerebral cortex [nTPM]":"17.9","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"5.9","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"5.3","Tissue RNA - epididymis [nTPM]":"12.6","Tissue RNA - esophagus [nTPM]":"4.1","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"16.2","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"15.4","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"35.6","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"11.3","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"12.7","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"12.0","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"2.2","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"3.2","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"2.0","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"5.9","Tissue RNA - vagina [nTPM]":"3.2","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"4.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"10.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"17.0","Brain RNA - basal ganglia [nTPM]":"13.8","Brain RNA - cerebellum [nTPM]":"18.1","Brain RNA - cerebral cortex [nTPM]":"17.9","Brain RNA - hippocampal formation [nTPM]":"16.2","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"35.6","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.3","Single Cell Type RNA - Astrocytes [nTPM]":"18.3","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"46.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"35.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"105.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"37.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"88.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"32.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"45.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.4","Single Cell Type RNA - Urothelial cells [nTPM]":"13.4"},{"Gene":"KCNJ10","Gene synonym":["Kir1.2","Kir4.1"],"Ensembl":"ENSG00000177807","Gene description":"Potassium inwardly rectifying channel subfamily J member 10","Uniprot":["P78508"],"Chromosome":"1","Position":"159998651-160070160","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Deafness","Disease variant","Epilepsy","FDA approved drug targets","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"100.7","kidney":"28.0","retina":"36.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"93.0","Muller glia cells":"75.7","Oligodendrocyte precursor cells":"35.7","Oligodendrocytes":"93.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"27.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"6.7","SK-MEL-30":"2.1","U-266\/70":"2.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078302"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078302":"AB_2732378"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"56.7","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"86.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"100.2","Tissue RNA - cerebral cortex [nTPM]":"58.4","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"8.7","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"51.4","Tissue RNA - hypothalamus [nTPM]":"78.7","Tissue RNA - kidney [nTPM]":"28.0","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"7.3","Tissue RNA - medulla oblongata [nTPM]":"92.7","Tissue RNA - midbrain [nTPM]":"94.7","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"87.5","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"36.7","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"71.8","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"83.6","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"100.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"6.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.2","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"2.1","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"2.0","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"56.7","Brain RNA - basal ganglia [nTPM]":"86.3","Brain RNA - cerebellum [nTPM]":"100.2","Brain RNA - cerebral cortex [nTPM]":"58.4","Brain RNA - hippocampal formation [nTPM]":"51.4","Brain RNA - hypothalamus [nTPM]":"78.7","Brain RNA - medulla oblongata [nTPM]":"92.7","Brain RNA - midbrain [nTPM]":"94.7","Brain RNA - pons [nTPM]":"87.5","Brain RNA - spinal cord [nTPM]":"71.8","Brain RNA - thalamus [nTPM]":"83.6","Brain RNA - white matter [nTPM]":"100.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"93.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"13.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"75.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"93.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNJ13","Gene synonym":["Kir1.4","Kir7.1","LCA16"],"Ensembl":"ENSG00000115474","Gene description":"Potassium inwardly rectifying channel subfamily J member 13","Uniprot":["O60928"],"Chromosome":"2","Position":"232765802-232776565","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Cataract","Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"choroid plexus":"159.5","intestine":"91.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Muller glia cells":"54.8","Proximal enterocytes":"217.4","Undifferentiated cells":"68.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"5.9"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"7.3","hippocampal formation":"8.0","thalamus":"5.3","white matter":"3.4"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"1.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051609"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA051609":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"159.5","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"7.9","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"8.0","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"3.3","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"15.8","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"13.7","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"91.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"8.0","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"54.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"8.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"217.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"68.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNMA1","Gene synonym":["KCa1.1","mSLO1","SLO"],"Ensembl":"ENSG00000156113","Gene description":"Potassium calcium-activated channel subfamily M alpha 1","Uniprot":["Q12791"],"Chromosome":"10","Position":"76869601-77638369","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"138.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"471.1","Bipolar cells":"409.8","Excitatory neurons":"1023.7","Inhibitory neurons":"635.9","Oligodendrocyte precursor cells":"708.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"2.4","non-classical monocyte":"1.7"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"monocytes":"2.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"100.8","hTERT-HME1":"115.3","PC-3":"159.6","U-138 MG":"112.6","U-87 MG":"109.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054648"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054648":"AB_2682556"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"12.6","Tissue RNA - amygdala [nTPM]":"36.2","Tissue RNA - appendix [nTPM]":"8.9","Tissue RNA - basal ganglia [nTPM]":"38.0","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"15.8","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"45.0","Tissue RNA - cervix [nTPM]":"54.4","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"118.2","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"138.7","Tissue RNA - epididymis [nTPM]":"31.4","Tissue RNA - esophagus [nTPM]":"33.7","Tissue RNA - fallopian tube [nTPM]":"47.8","Tissue RNA - gallbladder [nTPM]":"22.4","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"36.4","Tissue RNA - hypothalamus [nTPM]":"10.1","Tissue RNA - kidney [nTPM]":"11.4","Tissue RNA - liver [nTPM]":"19.2","Tissue RNA - lung [nTPM]":"9.6","Tissue RNA - lymph node [nTPM]":"7.8","Tissue RNA - medulla oblongata [nTPM]":"4.8","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"13.9","Tissue RNA - pancreas [nTPM]":"8.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"26.9","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"5.7","Tissue RNA - prostate [nTPM]":"48.3","Tissue RNA - rectum [nTPM]":"21.1","Tissue RNA - retina [nTPM]":"40.2","Tissue RNA - salivary gland [nTPM]":"42.8","Tissue RNA - seminal vesicle [nTPM]":"76.1","Tissue RNA - skeletal muscle [nTPM]":"96.6","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"23.3","Tissue RNA - smooth muscle [nTPM]":"92.8","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"24.1","Tissue RNA - stomach 1 [nTPM]":"33.6","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"18.7","Tissue RNA - tonsil [nTPM]":"3.5","Tissue RNA - urinary bladder [nTPM]":"44.3","Tissue RNA - vagina [nTPM]":"24.6","Tissue RNA - white matter [nTPM]":"28.4","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"30.3","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"4.6","Cell RNA - ASC TERT1 [nTPM]":"24.8","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"100.8","Cell RNA - BJ hTERT+ [nTPM]":"89.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.8","Cell RNA - CACO-2 [nTPM]":"6.7","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"75.9","Cell RNA - GAMG [nTPM]":"56.8","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"59.0","Cell RNA - HBF TERT88 [nTPM]":"14.6","Cell RNA - HDLM-2 [nTPM]":"60.9","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"45.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"17.4","Cell RNA - hTCEpi [nTPM]":"10.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.3","Cell RNA - hTERT-HME1 [nTPM]":"115.3","Cell RNA - hTERT-RPE1 [nTPM]":"84.0","Cell RNA - HUVEC TERT2 [nTPM]":"9.8","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"42.6","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"159.6","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"3.6","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"9.1","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"11.9","Cell RNA - T-47d [nTPM]":"12.2","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"65.4","Cell RNA - U-138 MG [nTPM]":"112.6","Cell RNA - U-2 OS [nTPM]":"12.7","Cell RNA - U-2197 [nTPM]":"20.6","Cell RNA - U-251 MG [nTPM]":"90.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"109.8","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"45.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"36.2","Brain RNA - basal ganglia [nTPM]":"38.0","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"45.0","Brain RNA - hippocampal formation [nTPM]":"36.4","Brain RNA - hypothalamus [nTPM]":"10.1","Brain RNA - medulla oblongata [nTPM]":"4.8","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"5.7","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"28.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.3","Single Cell Type RNA - Astrocytes [nTPM]":"471.1","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"71.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"409.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"4.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"3.3","Single Cell Type RNA - Early spermatids [nTPM]":"74.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.9","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1023.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"16.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"27.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"635.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"59.6","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"106.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.9","Single Cell Type RNA - Late spermatids [nTPM]":"63.1","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"36.7","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"133.0","Single Cell Type RNA - monocytes [nTPM]":"4.0","Single Cell Type RNA - Muller glia cells [nTPM]":"52.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"708.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"8.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"64.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"177.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.4"},{"Gene":"KCNQ2","Gene synonym":["BFNC","EBN","EBN1","ENB1","HNSPC","KCNA11","Kv7.2"],"Ensembl":"ENSG00000075043","Gene description":"Potassium voltage-gated channel subfamily Q member 2","Uniprot":["O43526"],"Chromosome":"20","Position":"63400208-63472677","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"91.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"16.5","Excitatory neurons":"61.7","Horizontal cells":"13.5","Inhibitory neurons":"37.5","Oligodendrocyte precursor cells":"50.8","Spermatogonia":"28.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"8.7"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"55.7","basal ganglia":"37.2","cerebellum":"27.8","cerebral cortex":"91.9","hippocampal formation":"68.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"21.2","AN3-CA":"35.0","NTERA-2":"19.3","SCLC-21H":"67.8","SH-SY5Y":"119.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016642","HPA057112"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA016642":"AB_1855555","HPA057112":"AB_2683339"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"55.7","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"37.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"27.8","Tissue RNA - cerebral cortex [nTPM]":"91.9","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"68.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"19.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"10.6","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"12.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"21.2","Cell RNA - AN3-CA [nTPM]":"35.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"8.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"19.3","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"67.8","Cell RNA - SH-SY5Y [nTPM]":"119.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"55.7","Brain RNA - basal ganglia [nTPM]":"37.2","Brain RNA - cerebellum [nTPM]":"27.8","Brain RNA - cerebral cortex [nTPM]":"91.9","Brain RNA - hippocampal formation [nTPM]":"68.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"12.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"16.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"7.4","Single Cell Type RNA - Spermatogonia [nTPM]":"28.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNQ3","Gene synonym":["EBN2","Kv7.3"],"Ensembl":"ENSG00000184156","Gene description":"Potassium voltage-gated channel subfamily Q member 3","Uniprot":["O43525"],"Chromosome":"8","Position":"132120859-132481095","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"23.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"501.5","Inhibitory neurons":"485.6","Microglial cells":"502.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"6.6","JURKAT":"3.8","RPMI-8226":"2.8","U-2 OS":"4.3","U-87 MG":"3.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"21.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"23.7","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"9.1","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"8.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"16.0","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"8.7","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1.5","Cell RNA - GAMG [nTPM]":"2.5","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"2.5","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.7","Cell RNA - hTERT-HME1 [nTPM]":"6.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"2.8","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"21.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"23.7","Brain RNA - hippocampal formation [nTPM]":"9.1","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"8.1","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"16.0","Brain RNA - white matter [nTPM]":"8.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.0","Single Cell Type RNA - Astrocytes [nTPM]":"84.5","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"501.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"485.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"502.2","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"117.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KCNQ4","Gene synonym":["DFNA2","Kv7.4"],"Ensembl":"ENSG00000117013","Gene description":"Potassium voltage-gated channel subfamily Q member 4","Uniprot":["P56696"],"Chromosome":"1","Position":"40783787-40840452","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Hearing","Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.1","intestine":"5.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"5.1","Inhibitory neurons":"9.7","Muller glia cells":"4.2","Sertoli cells":"6.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"5.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"1.8","HEK 293":"2.2","K-562":"2.6","MCF7":"1.4","REH":"1.3","THP-1":"1.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018305"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018305":"AB_1855556"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"2.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KCNT1","Gene synonym":["KCa4.1","KIAA1422","SLACK","Slo2.2"],"Ensembl":"ENSG00000107147","Gene description":"Potassium sodium-activated channel subfamily T member 1","Uniprot":["Q5JUK3"],"Chromosome":"9","Position":"135702185-135795508","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"37.1","lymphoid tissue":"15.8","skeletal muscle":"13.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Excitatory neurons":"60.1","Inhibitory neurons":"55.0","Theca cells":"21.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"0.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"37.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"2.5","RPMI-8226":"1.8","SCLC-21H":"3.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"42.8"},"Antibody":["HPA059880"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059880":"AB_2684149"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-13"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"7.9","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"37.1","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"8.7","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"2.8","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"15.8","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"8.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"2.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"7.9","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"37.1","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"2.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"60.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"21.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNT2","Gene synonym":["KCa4.2","SLICK","SLO2.1"],"Ensembl":"ENSG00000162687","Gene description":"Potassium sodium-activated channel subfamily T member 2","Uniprot":["Q6UVM3"],"Chromosome":"1","Position":"196225779-196609225","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"3.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"220.2","Inhibitory neurons":"240.5","Oligodendrocyte precursor cells":"310.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"3.2","hTERT-RPE1":"9.0","SCLC-21H":"7.5","SH-SY5Y":"5.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051218"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA051218":"AB_2681392"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.8","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"9.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"7.5","Cell RNA - SH-SY5Y [nTPM]":"5.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"13.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"220.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"6.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"240.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.3","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"310.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"3.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"KCNV2","Gene synonym":["Kv8.2"],"Ensembl":"ENSG00000168263","Gene description":"Potassium voltage-gated channel modifier subfamily V member 2","Uniprot":["Q8TDN2"],"Chromosome":"9","Position":"2717510-2730037","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"59","RNA tissue specific nTPM":{"retina":"289.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"515.0","Rod photoreceptor cells":"530.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"78","RNA cancer specific FPKM":{"testis cancer":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031131"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031131":"AB_10609996"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"289.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"4.9","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"49.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"515.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"81.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"25.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"69.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"530.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"7.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCTD17","Gene synonym":["FLJ12242"],"Ensembl":"ENSG00000100379","Gene description":"Potassium channel tetramerization domain containing 17","Uniprot":["Q8N5Z5"],"Chromosome":"22","Position":"37051736-37063390","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"113.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"90.8"},"Antibody":["HPA018459"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018459":"AB_1852169"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.22e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.13e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.2","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"64.8","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"113.7","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"46.0","Tissue RNA - cerebral cortex [nTPM]":"71.6","Tissue RNA - cervix [nTPM]":"14.2","Tissue RNA - choroid plexus [nTPM]":"44.4","Tissue RNA - colon [nTPM]":"15.9","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"14.9","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"26.6","Tissue RNA - hippocampal formation [nTPM]":"68.0","Tissue RNA - hypothalamus [nTPM]":"54.1","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"3.5","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"10.6","Tissue RNA - medulla oblongata [nTPM]":"44.8","Tissue RNA - midbrain [nTPM]":"70.4","Tissue RNA - ovary [nTPM]":"13.7","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"7.8","Tissue RNA - pituitary gland [nTPM]":"43.0","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"52.4","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"3.6","Tissue RNA - salivary gland [nTPM]":"3.4","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"21.1","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"43.8","Tissue RNA - spleen [nTPM]":"11.1","Tissue RNA - stomach 1 [nTPM]":"7.9","Tissue RNA - testis [nTPM]":"46.0","Tissue RNA - thalamus [nTPM]":"83.8","Tissue RNA - thymus [nTPM]":"7.0","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"6.9","Tissue RNA - urinary bladder [nTPM]":"16.9","Tissue RNA - vagina [nTPM]":"13.0","Tissue RNA - white matter [nTPM]":"55.5","Cell RNA - A-431 [nTPM]":"15.9","Cell RNA - A549 [nTPM]":"20.5","Cell RNA - AF22 [nTPM]":"31.7","Cell RNA - AN3-CA [nTPM]":"23.7","Cell RNA - ASC diff [nTPM]":"14.9","Cell RNA - ASC TERT1 [nTPM]":"14.8","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"16.2","Cell RNA - BJ hTERT+ [nTPM]":"15.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.3","Cell RNA - CACO-2 [nTPM]":"4.4","Cell RNA - CAPAN-2 [nTPM]":"4.6","Cell RNA - Daudi [nTPM]":"12.2","Cell RNA - EFO-21 [nTPM]":"10.9","Cell RNA - fHDF\/TERT166 [nTPM]":"20.8","Cell RNA - GAMG [nTPM]":"20.3","Cell RNA - HaCaT [nTPM]":"4.2","Cell RNA - HAP1 [nTPM]":"10.0","Cell RNA - HBEC3-KT [nTPM]":"19.0","Cell RNA - HBF TERT88 [nTPM]":"10.9","Cell RNA - HDLM-2 [nTPM]":"23.8","Cell RNA - HEK 293 [nTPM]":"26.8","Cell RNA - HEL [nTPM]":"5.2","Cell RNA - HeLa [nTPM]":"5.6","Cell RNA - Hep G2 [nTPM]":"4.9","Cell RNA - HHSteC [nTPM]":"22.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"6.1","Cell RNA - HSkMC [nTPM]":"17.3","Cell RNA - hTCEpi [nTPM]":"9.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.6","Cell RNA - hTERT-HME1 [nTPM]":"5.8","Cell RNA - hTERT-RPE1 [nTPM]":"17.5","Cell RNA - HUVEC TERT2 [nTPM]":"33.6","Cell RNA - JURKAT [nTPM]":"15.9","Cell RNA - K-562 [nTPM]":"1.2","Cell RNA - Karpas-707 [nTPM]":"13.2","Cell RNA - LHCN-M2 [nTPM]":"16.5","Cell RNA - MCF7 [nTPM]":"12.8","Cell RNA - MOLT-4 [nTPM]":"11.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"20.3","Cell RNA - OE19 [nTPM]":"9.4","Cell RNA - PC-3 [nTPM]":"17.4","Cell RNA - REH [nTPM]":"19.8","Cell RNA - RH-30 [nTPM]":"8.4","Cell RNA - RPMI-8226 [nTPM]":"3.6","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"4.1","Cell RNA - SCLC-21H [nTPM]":"26.4","Cell RNA - SH-SY5Y [nTPM]":"32.9","Cell RNA - SiHa [nTPM]":"15.0","Cell RNA - SK-BR-3 [nTPM]":"14.1","Cell RNA - SK-MEL-30 [nTPM]":"7.5","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"3.8","Cell RNA - THP-1 [nTPM]":"4.2","Cell RNA - TIME [nTPM]":"19.6","Cell RNA - U-138 MG [nTPM]":"33.5","Cell RNA - U-2 OS [nTPM]":"31.2","Cell RNA - U-2197 [nTPM]":"16.0","Cell RNA - U-251 MG [nTPM]":"12.0","Cell RNA - U-266\/70 [nTPM]":"17.7","Cell RNA - U-266\/84 [nTPM]":"5.5","Cell RNA - U-698 [nTPM]":"2.0","Cell RNA - U-87 MG [nTPM]":"29.6","Cell RNA - U-937 [nTPM]":"7.3","Cell RNA - WM-115 [nTPM]":"18.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"64.8","Brain RNA - basal ganglia [nTPM]":"113.7","Brain RNA - cerebellum [nTPM]":"46.0","Brain RNA - cerebral cortex [nTPM]":"71.6","Brain RNA - hippocampal formation [nTPM]":"68.0","Brain RNA - hypothalamus [nTPM]":"54.1","Brain RNA - medulla oblongata [nTPM]":"44.8","Brain RNA - midbrain [nTPM]":"70.4","Brain RNA - pons [nTPM]":"52.4","Brain RNA - spinal cord [nTPM]":"43.8","Brain RNA - thalamus [nTPM]":"83.8","Brain RNA - white matter [nTPM]":"55.5","Single Cell Type RNA - Adipocytes [nTPM]":"8.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"5.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.9","Single Cell Type RNA - Early spermatids [nTPM]":"24.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.7","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"9.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"12.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.6","Single Cell Type RNA - Langerhans cells [nTPM]":"17.0","Single Cell Type RNA - Late spermatids [nTPM]":"28.1","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"9.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"13.0","Single Cell Type RNA - Muller glia cells [nTPM]":"16.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.2","Single Cell Type RNA - Paneth cells [nTPM]":"16.0","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"4.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.7","Single Cell Type RNA - Spermatocytes [nTPM]":"19.7","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - T-cells [nTPM]":"8.5","Single Cell Type RNA - Theca cells [nTPM]":"10.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.4"},{"Gene":"KCTD7","Gene synonym":["CLN14","EPM3","FLJ32069"],"Ensembl":"ENSG00000243335","Gene description":"Potassium channel tetramerization domain containing 7","Uniprot":["Q96MP8"],"Chromosome":"7","Position":"66628881-66649067","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"65.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"37.5","Oligodendrocytes":"42.7","Rod photoreceptor cells":"53.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.07e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"11.6","Tissue RNA - amygdala [nTPM]":"18.3","Tissue RNA - appendix [nTPM]":"8.7","Tissue RNA - basal ganglia [nTPM]":"21.8","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"22.2","Tissue RNA - cerebral cortex [nTPM]":"20.4","Tissue RNA - cervix [nTPM]":"16.0","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"17.0","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"14.0","Tissue RNA - epididymis [nTPM]":"13.7","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"13.0","Tissue RNA - gallbladder [nTPM]":"7.1","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"17.8","Tissue RNA - hypothalamus [nTPM]":"19.3","Tissue RNA - kidney [nTPM]":"8.7","Tissue RNA - liver [nTPM]":"5.9","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"24.7","Tissue RNA - midbrain [nTPM]":"21.6","Tissue RNA - ovary [nTPM]":"20.8","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"10.0","Tissue RNA - pituitary gland [nTPM]":"13.8","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"24.6","Tissue RNA - prostate [nTPM]":"10.9","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"65.7","Tissue RNA - salivary gland [nTPM]":"6.6","Tissue RNA - seminal vesicle [nTPM]":"10.1","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"19.7","Tissue RNA - spleen [nTPM]":"10.9","Tissue RNA - stomach 1 [nTPM]":"10.8","Tissue RNA - testis [nTPM]":"17.5","Tissue RNA - thalamus [nTPM]":"23.1","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"6.6","Tissue RNA - tonsil [nTPM]":"12.1","Tissue RNA - urinary bladder [nTPM]":"16.6","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"32.1","Cell RNA - A-431 [nTPM]":"4.5","Cell RNA - A549 [nTPM]":"6.3","Cell RNA - AF22 [nTPM]":"17.5","Cell RNA - AN3-CA [nTPM]":"12.8","Cell RNA - ASC diff [nTPM]":"8.2","Cell RNA - ASC TERT1 [nTPM]":"10.5","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"6.6","Cell RNA - BJ hTERT+ [nTPM]":"7.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.6","Cell RNA - CACO-2 [nTPM]":"9.0","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"14.4","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"8.3","Cell RNA - GAMG [nTPM]":"25.0","Cell RNA - HaCaT [nTPM]":"2.4","Cell RNA - HAP1 [nTPM]":"14.4","Cell RNA - HBEC3-KT [nTPM]":"2.3","Cell RNA - HBF TERT88 [nTPM]":"10.4","Cell RNA - HDLM-2 [nTPM]":"13.0","Cell RNA - HEK 293 [nTPM]":"6.4","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"16.0","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"4.4","Cell RNA - HL-60 [nTPM]":"3.9","Cell RNA - HMC-1 [nTPM]":"11.6","Cell RNA - HSkMC [nTPM]":"6.6","Cell RNA - hTCEpi [nTPM]":"7.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.4","Cell RNA - hTERT-HME1 [nTPM]":"5.0","Cell RNA - hTERT-RPE1 [nTPM]":"14.4","Cell RNA - HUVEC TERT2 [nTPM]":"5.3","Cell RNA - JURKAT [nTPM]":"6.9","Cell RNA - K-562 [nTPM]":"13.8","Cell RNA - Karpas-707 [nTPM]":"12.5","Cell RNA - LHCN-M2 [nTPM]":"8.5","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"3.8","Cell RNA - NB-4 [nTPM]":"5.7","Cell RNA - NTERA-2 [nTPM]":"11.1","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"4.7","Cell RNA - RH-30 [nTPM]":"7.2","Cell RNA - RPMI-8226 [nTPM]":"5.8","Cell RNA - RPTEC TERT1 [nTPM]":"6.9","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"8.8","Cell RNA - SH-SY5Y [nTPM]":"16.2","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"3.5","Cell RNA - SK-MEL-30 [nTPM]":"15.4","Cell RNA - SuSa [nTPM]":"16.8","Cell RNA - T-47d [nTPM]":"5.6","Cell RNA - THP-1 [nTPM]":"4.5","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"13.1","Cell RNA - U-2 OS [nTPM]":"9.5","Cell RNA - U-2197 [nTPM]":"4.5","Cell RNA - U-251 MG [nTPM]":"5.8","Cell RNA - U-266\/70 [nTPM]":"5.4","Cell RNA - U-266\/84 [nTPM]":"4.0","Cell RNA - U-698 [nTPM]":"11.2","Cell RNA - U-87 MG [nTPM]":"17.2","Cell RNA - U-937 [nTPM]":"5.2","Cell RNA - WM-115 [nTPM]":"10.2","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"6.9","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"3.6","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"2.6","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"18.3","Brain RNA - basal ganglia [nTPM]":"21.8","Brain RNA - cerebellum [nTPM]":"22.2","Brain RNA - cerebral cortex [nTPM]":"20.4","Brain RNA - hippocampal formation [nTPM]":"17.8","Brain RNA - hypothalamus [nTPM]":"19.3","Brain RNA - medulla oblongata [nTPM]":"24.7","Brain RNA - midbrain [nTPM]":"21.6","Brain RNA - pons [nTPM]":"24.6","Brain RNA - spinal cord [nTPM]":"19.7","Brain RNA - thalamus [nTPM]":"23.1","Brain RNA - white matter [nTPM]":"32.1","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.0","Single Cell Type RNA - Astrocytes [nTPM]":"20.2","Single Cell Type RNA - B-cells [nTPM]":"10.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"17.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.2","Single Cell Type RNA - dendritic cells [nTPM]":"9.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"9.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.3","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"12.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.9","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"18.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"6.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"4.2","Single Cell Type RNA - Muller glia cells [nTPM]":"20.3","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"5.2","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"7.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"13.0","Single Cell Type RNA - Spermatogonia [nTPM]":"9.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - T-cells [nTPM]":"10.7","Single Cell Type RNA - Theca cells [nTPM]":"5.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"KIAA1549","Gene synonym":[],"Ensembl":"ENSG00000122778","Gene description":"KIAA1549","Uniprot":["Q9HCM3"],"Chromosome":"7","Position":"138831381-138981389","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"56.3","Excitatory neurons":"92.2","Inhibitory neurons":"54.6","Oligodendrocyte precursor cells":"69.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"PC-3":"20.6","SH-SY5Y":"21.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019560"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA019560":"AB_1852418"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"4.3","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"6.3","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"4.9","Cell RNA - A549 [nTPM]":"9.2","Cell RNA - AF22 [nTPM]":"9.1","Cell RNA - AN3-CA [nTPM]":"14.9","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"4.2","Cell RNA - BJ [nTPM]":"5.2","Cell RNA - BJ hTERT+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.4","Cell RNA - CACO-2 [nTPM]":"8.4","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.9","Cell RNA - fHDF\/TERT166 [nTPM]":"8.2","Cell RNA - GAMG [nTPM]":"8.6","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"5.7","Cell RNA - HBEC3-KT [nTPM]":"1.4","Cell RNA - HBF TERT88 [nTPM]":"3.6","Cell RNA - HDLM-2 [nTPM]":"2.5","Cell RNA - HEK 293 [nTPM]":"3.8","Cell RNA - HEL [nTPM]":"2.6","Cell RNA - HeLa [nTPM]":"11.5","Cell RNA - Hep G2 [nTPM]":"2.2","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"3.8","Cell RNA - HMC-1 [nTPM]":"3.2","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"2.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"3.5","Cell RNA - HUVEC TERT2 [nTPM]":"4.8","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"1.7","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"3.6","Cell RNA - MCF7 [nTPM]":"4.5","Cell RNA - MOLT-4 [nTPM]":"2.9","Cell RNA - NB-4 [nTPM]":"4.7","Cell RNA - NTERA-2 [nTPM]":"7.8","Cell RNA - OE19 [nTPM]":"4.1","Cell RNA - PC-3 [nTPM]":"20.6","Cell RNA - REH [nTPM]":"6.8","Cell RNA - RH-30 [nTPM]":"4.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"3.3","Cell RNA - SCLC-21H [nTPM]":"11.8","Cell RNA - SH-SY5Y [nTPM]":"21.5","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"5.2","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"3.7","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"2.9","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"5.1","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"1.4","Cell RNA - WM-115 [nTPM]":"7.1","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"4.3","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"18.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"92.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.0","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"13.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"69.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"2.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"KIF1A","Gene synonym":["ATSV","C2orf20","SPG30","UNC104"],"Ensembl":"ENSG00000130294","Gene description":"Kinesin family member 1A","Uniprot":["Q12756"],"Chromosome":"2","Position":"240713761-240824293","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Mental retardation","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"115.0","pancreas":"34.1","pituitary gland":"42.1","retina":"58.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"393.8","Cone photoreceptor cells":"419.1","Horizontal cells":"536.7","Muller glia cells":"116.4","Rod photoreceptor cells":"176.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"20.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"62.5","HAP1":"146.0","SCLC-21H":"276.0","SH-SY5Y":"52.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005442"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA005442":"AB_1079210"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.97e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"12.4","Tissue RNA - amygdala [nTPM]":"54.0","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"55.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"22.4","Tissue RNA - cerebral cortex [nTPM]":"113.6","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"13.7","Tissue RNA - hippocampal formation [nTPM]":"71.8","Tissue RNA - hypothalamus [nTPM]":"25.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"115.0","Tissue RNA - midbrain [nTPM]":"47.4","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"34.1","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"42.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"107.7","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"58.4","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"10.2","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"2.6","Tissue RNA - testis [nTPM]":"11.2","Tissue RNA - thalamus [nTPM]":"53.9","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"99.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"62.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"1.4","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"146.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"8.4","Cell RNA - HEK 293 [nTPM]":"10.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"14.4","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.5","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"8.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"1.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"276.0","Cell RNA - SH-SY5Y [nTPM]":"52.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"2.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"54.0","Brain RNA - basal ganglia [nTPM]":"55.6","Brain RNA - cerebellum [nTPM]":"22.4","Brain RNA - cerebral cortex [nTPM]":"113.6","Brain RNA - hippocampal formation [nTPM]":"71.8","Brain RNA - hypothalamus [nTPM]":"25.0","Brain RNA - medulla oblongata [nTPM]":"115.0","Brain RNA - midbrain [nTPM]":"47.4","Brain RNA - pons [nTPM]":"107.7","Brain RNA - spinal cord [nTPM]":"10.2","Brain RNA - thalamus [nTPM]":"53.9","Brain RNA - white matter [nTPM]":"99.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"50.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"393.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"419.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"57.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"536.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"72.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"116.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"50.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"176.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"46.2","Single Cell Type RNA - Spermatogonia [nTPM]":"20.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"3.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"KIF1B","Gene synonym":["CMT2","CMT2A","HMSNII","KIAA0591","KLP"],"Ensembl":"ENSG00000054523","Gene description":"Kinesin family member 1B","Uniprot":["O60333"],"Chromosome":"1","Position":"10210570-10381603","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":["Motor protein"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"103.6","retina":"127.4","skeletal muscle":"202.3","tongue":"150.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"413.9","Cone photoreceptor cells":"579.6","Excitatory neurons":"297.4","Inhibitory neurons":"281.6","Oligodendrocytes":"521.3","Rod photoreceptor cells":"389.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"5.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"5.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015177"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"CAB015177":"AB_2296564"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.91e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.1","Tissue RNA - adrenal gland [nTPM]":"14.8","Tissue RNA - amygdala [nTPM]":"64.1","Tissue RNA - appendix [nTPM]":"8.2","Tissue RNA - basal ganglia [nTPM]":"73.5","Tissue RNA - bone marrow [nTPM]":"16.0","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"68.4","Tissue RNA - cerebral cortex [nTPM]":"67.0","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"16.7","Tissue RNA - duodenum [nTPM]":"9.5","Tissue RNA - endometrium 1 [nTPM]":"15.5","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"18.3","Tissue RNA - fallopian tube [nTPM]":"10.5","Tissue RNA - gallbladder [nTPM]":"10.3","Tissue RNA - heart muscle [nTPM]":"29.7","Tissue RNA - hippocampal formation [nTPM]":"65.9","Tissue RNA - hypothalamus [nTPM]":"58.2","Tissue RNA - kidney [nTPM]":"14.6","Tissue RNA - liver [nTPM]":"12.1","Tissue RNA - lung [nTPM]":"11.0","Tissue RNA - lymph node [nTPM]":"4.2","Tissue RNA - medulla oblongata [nTPM]":"74.7","Tissue RNA - midbrain [nTPM]":"61.6","Tissue RNA - ovary [nTPM]":"15.7","Tissue RNA - pancreas [nTPM]":"13.2","Tissue RNA - parathyroid gland [nTPM]":"20.5","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"10.2","Tissue RNA - pons [nTPM]":"78.1","Tissue RNA - prostate [nTPM]":"11.9","Tissue RNA - rectum [nTPM]":"9.2","Tissue RNA - retina [nTPM]":"127.4","Tissue RNA - salivary gland [nTPM]":"12.8","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"202.3","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"10.6","Tissue RNA - smooth muscle [nTPM]":"15.2","Tissue RNA - spinal cord [nTPM]":"44.0","Tissue RNA - spleen [nTPM]":"7.3","Tissue RNA - stomach 1 [nTPM]":"9.4","Tissue RNA - testis [nTPM]":"19.7","Tissue RNA - thalamus [nTPM]":"60.4","Tissue RNA - thymus [nTPM]":"4.8","Tissue RNA - thyroid gland [nTPM]":"10.9","Tissue RNA - tongue [nTPM]":"150.9","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"11.6","Tissue RNA - vagina [nTPM]":"12.5","Tissue RNA - white matter [nTPM]":"103.6","Cell RNA - A-431 [nTPM]":"25.0","Cell RNA - A549 [nTPM]":"17.7","Cell RNA - AF22 [nTPM]":"81.3","Cell RNA - AN3-CA [nTPM]":"31.8","Cell RNA - ASC diff [nTPM]":"22.0","Cell RNA - ASC TERT1 [nTPM]":"24.6","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"24.0","Cell RNA - BJ hTERT+ [nTPM]":"16.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.0","Cell RNA - CACO-2 [nTPM]":"19.5","Cell RNA - CAPAN-2 [nTPM]":"12.2","Cell RNA - Daudi [nTPM]":"3.6","Cell RNA - EFO-21 [nTPM]":"23.4","Cell RNA - fHDF\/TERT166 [nTPM]":"38.9","Cell RNA - GAMG [nTPM]":"13.2","Cell RNA - HaCaT [nTPM]":"17.7","Cell RNA - HAP1 [nTPM]":"58.9","Cell RNA - HBEC3-KT [nTPM]":"18.8","Cell RNA - HBF TERT88 [nTPM]":"34.2","Cell RNA - HDLM-2 [nTPM]":"35.1","Cell RNA - HEK 293 [nTPM]":"19.3","Cell RNA - HEL [nTPM]":"14.7","Cell RNA - HeLa [nTPM]":"25.8","Cell RNA - Hep G2 [nTPM]":"23.0","Cell RNA - HHSteC [nTPM]":"17.6","Cell RNA - HL-60 [nTPM]":"5.2","Cell RNA - HMC-1 [nTPM]":"4.5","Cell RNA - HSkMC [nTPM]":"19.0","Cell RNA - hTCEpi [nTPM]":"18.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.3","Cell RNA - hTERT-HME1 [nTPM]":"26.7","Cell RNA - hTERT-RPE1 [nTPM]":"18.0","Cell RNA - HUVEC TERT2 [nTPM]":"31.1","Cell RNA - JURKAT [nTPM]":"15.4","Cell RNA - K-562 [nTPM]":"16.6","Cell RNA - Karpas-707 [nTPM]":"14.4","Cell RNA - LHCN-M2 [nTPM]":"27.7","Cell RNA - MCF7 [nTPM]":"7.5","Cell RNA - MOLT-4 [nTPM]":"5.9","Cell RNA - NB-4 [nTPM]":"5.2","Cell RNA - NTERA-2 [nTPM]":"17.9","Cell RNA - OE19 [nTPM]":"10.9","Cell RNA - PC-3 [nTPM]":"13.0","Cell RNA - REH [nTPM]":"24.6","Cell RNA - RH-30 [nTPM]":"47.2","Cell RNA - RPMI-8226 [nTPM]":"6.6","Cell RNA - RPTEC TERT1 [nTPM]":"10.3","Cell RNA - RT4 [nTPM]":"12.2","Cell RNA - SCLC-21H [nTPM]":"55.3","Cell RNA - SH-SY5Y [nTPM]":"27.0","Cell RNA - SiHa [nTPM]":"33.8","Cell RNA - SK-BR-3 [nTPM]":"16.1","Cell RNA - SK-MEL-30 [nTPM]":"32.9","Cell RNA - SuSa [nTPM]":"33.5","Cell RNA - T-47d [nTPM]":"11.5","Cell RNA - THP-1 [nTPM]":"7.0","Cell RNA - TIME [nTPM]":"36.4","Cell RNA - U-138 MG [nTPM]":"29.1","Cell RNA - U-2 OS [nTPM]":"18.4","Cell RNA - U-2197 [nTPM]":"33.0","Cell RNA - U-251 MG [nTPM]":"23.1","Cell RNA - U-266\/70 [nTPM]":"7.8","Cell RNA - U-266\/84 [nTPM]":"13.9","Cell RNA - U-698 [nTPM]":"7.7","Cell RNA - U-87 MG [nTPM]":"25.1","Cell RNA - U-937 [nTPM]":"15.8","Cell RNA - WM-115 [nTPM]":"14.9","Blood RNA - basophil [nTPM]":"2.3","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"5.5","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"64.1","Brain RNA - basal ganglia [nTPM]":"73.5","Brain RNA - cerebellum [nTPM]":"68.4","Brain RNA - cerebral cortex [nTPM]":"67.0","Brain RNA - hippocampal formation [nTPM]":"65.9","Brain RNA - hypothalamus [nTPM]":"58.2","Brain RNA - medulla oblongata [nTPM]":"74.7","Brain RNA - midbrain [nTPM]":"61.6","Brain RNA - pons [nTPM]":"78.1","Brain RNA - spinal cord [nTPM]":"44.0","Brain RNA - thalamus [nTPM]":"60.4","Brain RNA - white matter [nTPM]":"103.6","Single Cell Type RNA - Adipocytes [nTPM]":"38.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.6","Single Cell Type RNA - Astrocytes [nTPM]":"413.9","Single Cell Type RNA - B-cells [nTPM]":"9.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Bipolar cells [nTPM]":"248.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"120.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"18.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"579.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.9","Single Cell Type RNA - dendritic cells [nTPM]":"17.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.8","Single Cell Type RNA - Early spermatids [nTPM]":"85.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"41.8","Single Cell Type RNA - Endothelial cells [nTPM]":"39.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.8","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"297.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"42.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.1","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"104.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"37.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.1","Single Cell Type RNA - Horizontal cells [nTPM]":"139.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"281.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"22.0","Single Cell Type RNA - Langerhans cells [nTPM]":"43.5","Single Cell Type RNA - Late spermatids [nTPM]":"48.4","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"36.8","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"75.9","Single Cell Type RNA - monocytes [nTPM]":"19.5","Single Cell Type RNA - Muller glia cells [nTPM]":"56.1","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"238.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"521.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.8","Single Cell Type RNA - Paneth cells [nTPM]":"23.4","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"21.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"389.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"85.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"42.3","Single Cell Type RNA - Spermatocytes [nTPM]":"37.3","Single Cell Type RNA - Spermatogonia [nTPM]":"37.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"14.4","Single Cell Type RNA - Theca cells [nTPM]":"63.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.3","Single Cell Type RNA - Urothelial cells [nTPM]":"20.8"},{"Gene":"KIF21A","Gene synonym":["FEOM1","FLJ20052"],"Ensembl":"ENSG00000139116","Gene description":"Kinesin family member 21A","Uniprot":["Q7Z4S6"],"Chromosome":"12","Position":"39293228-39443390","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"70.3","retina":"77.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"308.6","Cone photoreceptor cells":"308.6","Inhibitory neurons":"221.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"7.1","MAIT T-cell":"3.4","memory CD4 T-cell":"4.4","memory CD8 T-cell":"7.3","naive CD8 T-cell":"4.8","NK-cell":"3.0","T-reg":"2.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"NK-cells":"3.0","T-cells":"7.3"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"SH-SY5Y":"187.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022079","HPA058432"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB022079":null,"HPA058432":"AB_2683717"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.07e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.5","Tissue RNA - adrenal gland [nTPM]":"12.1","Tissue RNA - amygdala [nTPM]":"37.4","Tissue RNA - appendix [nTPM]":"3.9","Tissue RNA - basal ganglia [nTPM]":"40.0","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"41.4","Tissue RNA - cerebral cortex [nTPM]":"51.2","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"8.0","Tissue RNA - colon [nTPM]":"11.9","Tissue RNA - duodenum [nTPM]":"9.0","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"20.9","Tissue RNA - fallopian tube [nTPM]":"33.7","Tissue RNA - gallbladder [nTPM]":"6.1","Tissue RNA - heart muscle [nTPM]":"19.2","Tissue RNA - hippocampal formation [nTPM]":"38.2","Tissue RNA - hypothalamus [nTPM]":"55.7","Tissue RNA - kidney [nTPM]":"26.5","Tissue RNA - liver [nTPM]":"20.5","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"67.4","Tissue RNA - midbrain [nTPM]":"46.6","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"13.2","Tissue RNA - parathyroid gland [nTPM]":"16.6","Tissue RNA - pituitary gland [nTPM]":"16.0","Tissue RNA - placenta [nTPM]":"5.7","Tissue RNA - pons [nTPM]":"70.3","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"77.6","Tissue RNA - salivary gland [nTPM]":"23.9","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"15.3","Tissue RNA - skin 1 [nTPM]":"12.7","Tissue RNA - small intestine [nTPM]":"10.3","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"39.3","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"12.5","Tissue RNA - thalamus [nTPM]":"46.5","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"5.9","Tissue RNA - vagina [nTPM]":"11.4","Tissue RNA - white matter [nTPM]":"44.3","Cell RNA - A-431 [nTPM]":"18.5","Cell RNA - A549 [nTPM]":"23.2","Cell RNA - AF22 [nTPM]":"31.8","Cell RNA - AN3-CA [nTPM]":"13.7","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"3.0","Cell RNA - BEWO [nTPM]":"25.4","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"42.2","Cell RNA - CAPAN-2 [nTPM]":"22.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"14.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"16.0","Cell RNA - HAP1 [nTPM]":"18.5","Cell RNA - HBEC3-KT [nTPM]":"11.2","Cell RNA - HBF TERT88 [nTPM]":"5.4","Cell RNA - HDLM-2 [nTPM]":"36.1","Cell RNA - HEK 293 [nTPM]":"14.7","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"40.6","Cell RNA - Hep G2 [nTPM]":"38.6","Cell RNA - HHSteC [nTPM]":"4.6","Cell RNA - HL-60 [nTPM]":"31.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"24.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.4","Cell RNA - hTERT-HME1 [nTPM]":"35.3","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"7.7","Cell RNA - JURKAT [nTPM]":"7.8","Cell RNA - K-562 [nTPM]":"35.4","Cell RNA - Karpas-707 [nTPM]":"36.9","Cell RNA - LHCN-M2 [nTPM]":"4.8","Cell RNA - MCF7 [nTPM]":"11.1","Cell RNA - MOLT-4 [nTPM]":"4.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"42.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"20.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"21.1","Cell RNA - RPTEC TERT1 [nTPM]":"22.3","Cell RNA - RT4 [nTPM]":"30.1","Cell RNA - SCLC-21H [nTPM]":"43.0","Cell RNA - SH-SY5Y [nTPM]":"187.6","Cell RNA - SiHa [nTPM]":"17.7","Cell RNA - SK-BR-3 [nTPM]":"27.7","Cell RNA - SK-MEL-30 [nTPM]":"10.8","Cell RNA - SuSa [nTPM]":"32.1","Cell RNA - T-47d [nTPM]":"32.2","Cell RNA - THP-1 [nTPM]":"3.9","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"3.4","Cell RNA - U-2 OS [nTPM]":"13.7","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"13.1","Cell RNA - U-266\/70 [nTPM]":"16.7","Cell RNA - U-266\/84 [nTPM]":"6.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"8.1","Cell RNA - U-937 [nTPM]":"4.4","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"7.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.4","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"7.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"37.4","Brain RNA - basal ganglia [nTPM]":"40.0","Brain RNA - cerebellum [nTPM]":"41.4","Brain RNA - cerebral cortex [nTPM]":"51.2","Brain RNA - hippocampal formation [nTPM]":"38.2","Brain RNA - hypothalamus [nTPM]":"55.7","Brain RNA - medulla oblongata [nTPM]":"67.4","Brain RNA - midbrain [nTPM]":"46.6","Brain RNA - pons [nTPM]":"70.3","Brain RNA - spinal cord [nTPM]":"39.3","Brain RNA - thalamus [nTPM]":"46.5","Brain RNA - white matter [nTPM]":"44.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.5","Single Cell Type RNA - Astrocytes [nTPM]":"205.7","Single Cell Type RNA - B-cells [nTPM]":"5.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"308.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"121.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"53.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"308.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.3","Single Cell Type RNA - dendritic cells [nTPM]":"36.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"27.8","Single Cell Type RNA - Early spermatids [nTPM]":"108.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"78.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"189.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"41.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"100.8","Single Cell Type RNA - Fibroblasts [nTPM]":"17.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.7","Single Cell Type RNA - granulocytes [nTPM]":"13.4","Single Cell Type RNA - Granulosa cells [nTPM]":"92.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"44.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.8","Single Cell Type RNA - Horizontal cells [nTPM]":"138.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"221.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.7","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"79.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"112.3","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"124.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"160.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.2","Single Cell Type RNA - Paneth cells [nTPM]":"20.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"30.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"53.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"193.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"186.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.4","Single Cell Type RNA - Spermatocytes [nTPM]":"57.2","Single Cell Type RNA - Spermatogonia [nTPM]":"24.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.1","Single Cell Type RNA - T-cells [nTPM]":"33.5","Single Cell Type RNA - Theca cells [nTPM]":"17.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.3","Single Cell Type RNA - Urothelial cells [nTPM]":"21.7"},{"Gene":"KIF3B","Gene synonym":["FLA8","KIAA0359","KLP-11"],"Ensembl":"ENSG00000101350","Gene description":"Kinesin family member 3B","Uniprot":["O15066"],"Chromosome":"20","Position":"32277651-32335011","Protein class":["Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":["Ciliopathy","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"106.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007119"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007119":"AB_1852498"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.44e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.2","Tissue RNA - adrenal gland [nTPM]":"14.0","Tissue RNA - amygdala [nTPM]":"25.1","Tissue RNA - appendix [nTPM]":"11.1","Tissue RNA - basal ganglia [nTPM]":"25.4","Tissue RNA - bone marrow [nTPM]":"8.5","Tissue RNA - breast [nTPM]":"12.1","Tissue RNA - cerebellum [nTPM]":"18.2","Tissue RNA - cerebral cortex [nTPM]":"25.5","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"34.6","Tissue RNA - colon [nTPM]":"18.7","Tissue RNA - duodenum [nTPM]":"19.9","Tissue RNA - endometrium 1 [nTPM]":"11.6","Tissue RNA - epididymis [nTPM]":"17.5","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"20.5","Tissue RNA - gallbladder [nTPM]":"14.9","Tissue RNA - heart muscle [nTPM]":"8.1","Tissue RNA - hippocampal formation [nTPM]":"30.3","Tissue RNA - hypothalamus [nTPM]":"20.8","Tissue RNA - kidney [nTPM]":"35.4","Tissue RNA - liver [nTPM]":"17.8","Tissue RNA - lung [nTPM]":"12.9","Tissue RNA - lymph node [nTPM]":"11.5","Tissue RNA - medulla oblongata [nTPM]":"20.8","Tissue RNA - midbrain [nTPM]":"22.7","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"23.0","Tissue RNA - parathyroid gland [nTPM]":"46.7","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"8.5","Tissue RNA - pons [nTPM]":"18.8","Tissue RNA - prostate [nTPM]":"11.7","Tissue RNA - rectum [nTPM]":"19.0","Tissue RNA - retina [nTPM]":"30.8","Tissue RNA - salivary gland [nTPM]":"11.1","Tissue RNA - seminal vesicle [nTPM]":"10.9","Tissue RNA - skeletal muscle [nTPM]":"8.4","Tissue RNA - skin 1 [nTPM]":"7.8","Tissue RNA - small intestine [nTPM]":"24.1","Tissue RNA - smooth muscle [nTPM]":"12.1","Tissue RNA - spinal cord [nTPM]":"22.4","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"17.6","Tissue RNA - testis [nTPM]":"22.2","Tissue RNA - thalamus [nTPM]":"26.9","Tissue RNA - thymus [nTPM]":"8.2","Tissue RNA - thyroid gland [nTPM]":"19.2","Tissue RNA - tongue [nTPM]":"5.6","Tissue RNA - tonsil [nTPM]":"11.9","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"21.4","Cell RNA - A-431 [nTPM]":"49.9","Cell RNA - A549 [nTPM]":"33.2","Cell RNA - AF22 [nTPM]":"22.6","Cell RNA - AN3-CA [nTPM]":"29.1","Cell RNA - ASC diff [nTPM]":"29.3","Cell RNA - ASC TERT1 [nTPM]":"46.3","Cell RNA - BEWO [nTPM]":"23.0","Cell RNA - BJ [nTPM]":"24.2","Cell RNA - BJ hTERT+ [nTPM]":"33.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.4","Cell RNA - CACO-2 [nTPM]":"56.9","Cell RNA - CAPAN-2 [nTPM]":"26.7","Cell RNA - Daudi [nTPM]":"26.7","Cell RNA - EFO-21 [nTPM]":"28.4","Cell RNA - fHDF\/TERT166 [nTPM]":"45.8","Cell RNA - GAMG [nTPM]":"40.8","Cell RNA - HaCaT [nTPM]":"31.4","Cell RNA - HAP1 [nTPM]":"29.3","Cell RNA - HBEC3-KT [nTPM]":"35.8","Cell RNA - HBF TERT88 [nTPM]":"36.3","Cell RNA - HDLM-2 [nTPM]":"12.7","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"23.1","Cell RNA - HeLa [nTPM]":"25.6","Cell RNA - Hep G2 [nTPM]":"28.2","Cell RNA - HHSteC [nTPM]":"18.6","Cell RNA - HL-60 [nTPM]":"19.6","Cell RNA - HMC-1 [nTPM]":"16.9","Cell RNA - HSkMC [nTPM]":"28.6","Cell RNA - hTCEpi [nTPM]":"25.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.5","Cell RNA - hTERT-HME1 [nTPM]":"19.5","Cell RNA - hTERT-RPE1 [nTPM]":"23.5","Cell RNA - HUVEC TERT2 [nTPM]":"23.7","Cell RNA - JURKAT [nTPM]":"10.7","Cell RNA - K-562 [nTPM]":"14.5","Cell RNA - Karpas-707 [nTPM]":"10.4","Cell RNA - LHCN-M2 [nTPM]":"23.4","Cell RNA - MCF7 [nTPM]":"22.8","Cell RNA - MOLT-4 [nTPM]":"9.1","Cell RNA - NB-4 [nTPM]":"8.9","Cell RNA - NTERA-2 [nTPM]":"12.2","Cell RNA - OE19 [nTPM]":"26.5","Cell RNA - PC-3 [nTPM]":"28.8","Cell RNA - REH [nTPM]":"8.3","Cell RNA - RH-30 [nTPM]":"37.1","Cell RNA - RPMI-8226 [nTPM]":"9.7","Cell RNA - RPTEC TERT1 [nTPM]":"29.2","Cell RNA - RT4 [nTPM]":"36.1","Cell RNA - SCLC-21H [nTPM]":"37.0","Cell RNA - SH-SY5Y [nTPM]":"31.1","Cell RNA - SiHa [nTPM]":"63.2","Cell RNA - SK-BR-3 [nTPM]":"16.7","Cell RNA - SK-MEL-30 [nTPM]":"24.7","Cell RNA - SuSa [nTPM]":"18.9","Cell RNA - T-47d [nTPM]":"36.8","Cell RNA - THP-1 [nTPM]":"15.1","Cell RNA - TIME [nTPM]":"28.9","Cell RNA - U-138 MG [nTPM]":"53.4","Cell RNA - U-2 OS [nTPM]":"36.4","Cell RNA - U-2197 [nTPM]":"31.4","Cell RNA - U-251 MG [nTPM]":"30.2","Cell RNA - U-266\/70 [nTPM]":"17.3","Cell RNA - U-266\/84 [nTPM]":"26.5","Cell RNA - U-698 [nTPM]":"13.5","Cell RNA - U-87 MG [nTPM]":"53.2","Cell RNA - U-937 [nTPM]":"33.7","Cell RNA - WM-115 [nTPM]":"22.2","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"3.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"3.2","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"25.1","Brain RNA - basal ganglia [nTPM]":"25.4","Brain RNA - cerebellum [nTPM]":"18.2","Brain RNA - cerebral cortex [nTPM]":"25.5","Brain RNA - hippocampal formation [nTPM]":"30.3","Brain RNA - hypothalamus [nTPM]":"20.8","Brain RNA - medulla oblongata [nTPM]":"20.8","Brain RNA - midbrain [nTPM]":"22.7","Brain RNA - pons [nTPM]":"18.8","Brain RNA - spinal cord [nTPM]":"22.4","Brain RNA - thalamus [nTPM]":"26.9","Brain RNA - white matter [nTPM]":"21.4","Single Cell Type RNA - Adipocytes [nTPM]":"10.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.4","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"12.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"32.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"15.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"106.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"10.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"67.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"34.4","Single Cell Type RNA - Early spermatids [nTPM]":"67.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.3","Single Cell Type RNA - Endothelial cells [nTPM]":"16.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"39.4","Single Cell Type RNA - Erythroid cells [nTPM]":"6.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"39.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.3","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"13.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"28.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.1","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"88.2","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"9.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"10.9","Single Cell Type RNA - Muller glia cells [nTPM]":"19.2","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.4","Single Cell Type RNA - Paneth cells [nTPM]":"33.4","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"16.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"82.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"59.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"63.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.7","Single Cell Type RNA - Spermatocytes [nTPM]":"33.4","Single Cell Type RNA - Spermatogonia [nTPM]":"7.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"12.4","Single Cell Type RNA - Theca cells [nTPM]":"17.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.3","Single Cell Type RNA - Urothelial cells [nTPM]":"9.3"},{"Gene":"KIF5A","Gene synonym":["D12S1889","MY050","NKHC","SPG10"],"Ensembl":"ENSG00000155980","Gene description":"Kinesin family member 5A","Uniprot":["Q12840"],"Chromosome":"12","Position":"57546026-57586633","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Epilepsy","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"27","RNA tissue specific nTPM":{"brain":"1628.2","choroid plexus":"951.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"40.7","Early spermatids":"12.2","Endometrial stromal cells":"12.9","Excitatory neurons":"28.4","Horizontal cells":"26.9","Inhibitory neurons":"21.7","Late spermatids":"15.2","Rod photoreceptor cells":"11.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"26.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"33.2","K-562":"15.3","NTERA-2":"17.7","SCLC-21H":"34.4","U-87 MG":"14.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004469","HPA073448"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitotic spindle","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Mitotic spindle"],"Antibody RRID":{"HPA004469":"AB_1079212","HPA073448":"AB_2686601"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.23e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"1198.6","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"1243.7","Tissue RNA - bone marrow [nTPM]":"4.2","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"1056.4","Tissue RNA - cerebral cortex [nTPM]":"1628.2","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"951.3","Tissue RNA - colon [nTPM]":"4.5","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"1242.7","Tissue RNA - hypothalamus [nTPM]":"1056.4","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"1103.5","Tissue RNA - midbrain [nTPM]":"1046.7","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"21.3","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"1113.3","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"1.9","Tissue RNA - retina [nTPM]":"48.0","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"1002.7","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"1052.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"1313.2","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"5.7","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.5","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"3.2","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"2.5","Cell RNA - HDLM-2 [nTPM]":"33.2","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"7.0","Cell RNA - HHSteC [nTPM]":"1.9","Cell RNA - HL-60 [nTPM]":"1.5","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"1.0","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.6","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"15.3","Cell RNA - Karpas-707 [nTPM]":"9.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"17.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"1.1","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"34.4","Cell RNA - SH-SY5Y [nTPM]":"9.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.0","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"2.1","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"7.7","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"14.5","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"1198.6","Brain RNA - basal ganglia [nTPM]":"1243.7","Brain RNA - cerebellum [nTPM]":"1056.4","Brain RNA - cerebral cortex [nTPM]":"1628.2","Brain RNA - hippocampal formation [nTPM]":"1242.7","Brain RNA - hypothalamus [nTPM]":"1056.4","Brain RNA - medulla oblongata [nTPM]":"1103.5","Brain RNA - midbrain [nTPM]":"1046.7","Brain RNA - pons [nTPM]":"1113.3","Brain RNA - spinal cord [nTPM]":"1002.7","Brain RNA - thalamus [nTPM]":"1052.3","Brain RNA - white matter [nTPM]":"1313.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"40.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.2","Single Cell Type RNA - Late spermatids [nTPM]":"15.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KITLG","Gene synonym":["DFNA69","FPH2","Kitl","KL-1","MGF","SCF","SF","SLF"],"Ensembl":"ENSG00000049130","Gene description":"KIT ligand","Uniprot":["P21583"],"Chromosome":"12","Position":"88492793-88580851","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"83.6","Collecting duct cells":"69.9","Excitatory neurons":"46.5","Inhibitory neurons":"61.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"299.8","SK-BR-3":"118.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070395"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA070395":"AB_2686264"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.01e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.81e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.2","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"8.2","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"18.7","Tissue RNA - duodenum [nTPM]":"9.6","Tissue RNA - endometrium 1 [nTPM]":"15.1","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"18.5","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"16.0","Tissue RNA - liver [nTPM]":"2.3","Tissue RNA - lung [nTPM]":"31.6","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"6.0","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"15.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"22.6","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"8.8","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"18.8","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"3.5","Tissue RNA - stomach 1 [nTPM]":"17.4","Tissue RNA - testis [nTPM]":"6.3","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"14.4","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"12.3","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"14.3","Cell RNA - A549 [nTPM]":"7.1","Cell RNA - AF22 [nTPM]":"7.1","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"29.0","Cell RNA - ASC TERT1 [nTPM]":"61.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"77.6","Cell RNA - BJ hTERT+ [nTPM]":"60.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.4","Cell RNA - CACO-2 [nTPM]":"299.8","Cell RNA - CAPAN-2 [nTPM]":"11.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.2","Cell RNA - fHDF\/TERT166 [nTPM]":"73.3","Cell RNA - GAMG [nTPM]":"14.9","Cell RNA - HaCaT [nTPM]":"49.5","Cell RNA - HAP1 [nTPM]":"11.5","Cell RNA - HBEC3-KT [nTPM]":"20.1","Cell RNA - HBF TERT88 [nTPM]":"14.2","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"9.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"9.5","Cell RNA - Hep G2 [nTPM]":"2.6","Cell RNA - HHSteC [nTPM]":"4.4","Cell RNA - HL-60 [nTPM]":"1.9","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"53.5","Cell RNA - hTCEpi [nTPM]":"20.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.6","Cell RNA - hTERT-HME1 [nTPM]":"26.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.3","Cell RNA - HUVEC TERT2 [nTPM]":"17.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"6.8","Cell RNA - MCF7 [nTPM]":"2.5","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.8","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"12.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"25.0","Cell RNA - RT4 [nTPM]":"6.5","Cell RNA - SCLC-21H [nTPM]":"2.3","Cell RNA - SH-SY5Y [nTPM]":"4.8","Cell RNA - SiHa [nTPM]":"18.5","Cell RNA - SK-BR-3 [nTPM]":"118.9","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"6.5","Cell RNA - T-47d [nTPM]":"57.2","Cell RNA - THP-1 [nTPM]":"4.3","Cell RNA - TIME [nTPM]":"10.0","Cell RNA - U-138 MG [nTPM]":"60.7","Cell RNA - U-2 OS [nTPM]":"7.4","Cell RNA - U-2197 [nTPM]":"69.0","Cell RNA - U-251 MG [nTPM]":"6.8","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"8.4","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"5.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"42.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.3","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"83.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"16.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"69.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.8","Single Cell Type RNA - Endothelial cells [nTPM]":"43.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"34.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"61.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.7","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"4.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"KIZ","Gene synonym":["C20orf19","HT013","NCRNA00153","PLK1S1"],"Ensembl":"ENSG00000088970","Gene description":"Kizuna centrosomal protein","Uniprot":["Q2M2Z5"],"Chromosome":"20","Position":"21125983-21246622","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"203.0","Late spermatids":"127.3","Oligodendrocyte precursor cells":"198.5","Oligodendrocytes":"166.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"92.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.11e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.6","Tissue RNA - adrenal gland [nTPM]":"9.8","Tissue RNA - amygdala [nTPM]":"22.7","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"30.2","Tissue RNA - bone marrow [nTPM]":"10.7","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"27.7","Tissue RNA - cerebral cortex [nTPM]":"29.2","Tissue RNA - cervix [nTPM]":"32.5","Tissue RNA - choroid plexus [nTPM]":"20.2","Tissue RNA - colon [nTPM]":"72.2","Tissue RNA - duodenum [nTPM]":"15.1","Tissue RNA - endometrium 1 [nTPM]":"27.0","Tissue RNA - epididymis [nTPM]":"11.2","Tissue RNA - esophagus [nTPM]":"8.0","Tissue RNA - fallopian tube [nTPM]":"19.8","Tissue RNA - gallbladder [nTPM]":"12.6","Tissue RNA - heart muscle [nTPM]":"17.5","Tissue RNA - hippocampal formation [nTPM]":"21.8","Tissue RNA - hypothalamus [nTPM]":"25.1","Tissue RNA - kidney [nTPM]":"14.4","Tissue RNA - liver [nTPM]":"11.3","Tissue RNA - lung [nTPM]":"9.8","Tissue RNA - lymph node [nTPM]":"10.6","Tissue RNA - medulla oblongata [nTPM]":"30.7","Tissue RNA - midbrain [nTPM]":"27.9","Tissue RNA - ovary [nTPM]":"35.5","Tissue RNA - pancreas [nTPM]":"24.3","Tissue RNA - parathyroid gland [nTPM]":"14.6","Tissue RNA - pituitary gland [nTPM]":"23.3","Tissue RNA - placenta [nTPM]":"8.9","Tissue RNA - pons [nTPM]":"31.6","Tissue RNA - prostate [nTPM]":"19.3","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"20.2","Tissue RNA - salivary gland [nTPM]":"13.6","Tissue RNA - seminal vesicle [nTPM]":"23.8","Tissue RNA - skeletal muscle [nTPM]":"29.4","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"17.8","Tissue RNA - smooth muscle [nTPM]":"17.1","Tissue RNA - spinal cord [nTPM]":"25.2","Tissue RNA - spleen [nTPM]":"13.6","Tissue RNA - stomach 1 [nTPM]":"16.3","Tissue RNA - testis [nTPM]":"45.4","Tissue RNA - thalamus [nTPM]":"28.2","Tissue RNA - thymus [nTPM]":"16.6","Tissue RNA - thyroid gland [nTPM]":"26.9","Tissue RNA - tongue [nTPM]":"14.6","Tissue RNA - tonsil [nTPM]":"11.1","Tissue RNA - urinary bladder [nTPM]":"36.5","Tissue RNA - vagina [nTPM]":"22.9","Tissue RNA - white matter [nTPM]":"36.9","Cell RNA - A-431 [nTPM]":"7.5","Cell RNA - A549 [nTPM]":"5.9","Cell RNA - AF22 [nTPM]":"7.9","Cell RNA - AN3-CA [nTPM]":"7.5","Cell RNA - ASC diff [nTPM]":"27.3","Cell RNA - ASC TERT1 [nTPM]":"37.3","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"10.6","Cell RNA - BJ hTERT+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.4","Cell RNA - CACO-2 [nTPM]":"6.4","Cell RNA - CAPAN-2 [nTPM]":"6.1","Cell RNA - Daudi [nTPM]":"14.0","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"12.5","Cell RNA - GAMG [nTPM]":"9.3","Cell RNA - HaCaT [nTPM]":"6.2","Cell RNA - HAP1 [nTPM]":"8.0","Cell RNA - HBEC3-KT [nTPM]":"22.4","Cell RNA - HBF TERT88 [nTPM]":"12.2","Cell RNA - HDLM-2 [nTPM]":"7.9","Cell RNA - HEK 293 [nTPM]":"9.2","Cell RNA - HEL [nTPM]":"11.3","Cell RNA - HeLa [nTPM]":"11.2","Cell RNA - Hep G2 [nTPM]":"92.8","Cell RNA - HHSteC [nTPM]":"13.8","Cell RNA - HL-60 [nTPM]":"13.9","Cell RNA - HMC-1 [nTPM]":"9.2","Cell RNA - HSkMC [nTPM]":"28.2","Cell RNA - hTCEpi [nTPM]":"45.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.6","Cell RNA - hTERT-HME1 [nTPM]":"28.2","Cell RNA - hTERT-RPE1 [nTPM]":"20.8","Cell RNA - HUVEC TERT2 [nTPM]":"8.3","Cell RNA - JURKAT [nTPM]":"23.3","Cell RNA - K-562 [nTPM]":"18.6","Cell RNA - Karpas-707 [nTPM]":"18.8","Cell RNA - LHCN-M2 [nTPM]":"7.6","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"14.7","Cell RNA - NB-4 [nTPM]":"18.0","Cell RNA - NTERA-2 [nTPM]":"10.8","Cell RNA - OE19 [nTPM]":"13.5","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"9.2","Cell RNA - RH-30 [nTPM]":"22.5","Cell RNA - RPMI-8226 [nTPM]":"13.7","Cell RNA - RPTEC TERT1 [nTPM]":"9.7","Cell RNA - RT4 [nTPM]":"13.0","Cell RNA - SCLC-21H [nTPM]":"10.7","Cell RNA - SH-SY5Y [nTPM]":"20.9","Cell RNA - SiHa [nTPM]":"21.4","Cell RNA - SK-BR-3 [nTPM]":"11.4","Cell RNA - SK-MEL-30 [nTPM]":"22.4","Cell RNA - SuSa [nTPM]":"17.9","Cell RNA - T-47d [nTPM]":"7.3","Cell RNA - THP-1 [nTPM]":"27.1","Cell RNA - TIME [nTPM]":"7.8","Cell RNA - U-138 MG [nTPM]":"9.2","Cell RNA - U-2 OS [nTPM]":"8.0","Cell RNA - U-2197 [nTPM]":"7.2","Cell RNA - U-251 MG [nTPM]":"7.7","Cell RNA - U-266\/70 [nTPM]":"18.9","Cell RNA - U-266\/84 [nTPM]":"13.7","Cell RNA - U-698 [nTPM]":"10.5","Cell RNA - U-87 MG [nTPM]":"4.5","Cell RNA - U-937 [nTPM]":"15.5","Cell RNA - WM-115 [nTPM]":"8.4","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"5.0","Blood RNA - eosinophil [nTPM]":"12.5","Blood RNA - gdT-cell [nTPM]":"10.4","Blood RNA - intermediate monocyte [nTPM]":"5.6","Blood RNA - MAIT T-cell [nTPM]":"12.2","Blood RNA - memory B-cell [nTPM]":"11.7","Blood RNA - memory CD4 T-cell [nTPM]":"10.9","Blood RNA - memory CD8 T-cell [nTPM]":"10.5","Blood RNA - myeloid DC [nTPM]":"3.1","Blood RNA - naive B-cell [nTPM]":"11.4","Blood RNA - naive CD4 T-cell [nTPM]":"11.5","Blood RNA - naive CD8 T-cell [nTPM]":"12.6","Blood RNA - neutrophil [nTPM]":"16.5","Blood RNA - NK-cell [nTPM]":"8.4","Blood RNA - non-classical monocyte [nTPM]":"4.2","Blood RNA - plasmacytoid DC [nTPM]":"7.3","Blood RNA - T-reg [nTPM]":"14.3","Blood RNA - total PBMC [nTPM]":"5.0","Brain RNA - amygdala [nTPM]":"22.7","Brain RNA - basal ganglia [nTPM]":"30.2","Brain RNA - cerebellum [nTPM]":"27.7","Brain RNA - cerebral cortex [nTPM]":"29.2","Brain RNA - hippocampal formation [nTPM]":"21.8","Brain RNA - hypothalamus [nTPM]":"25.1","Brain RNA - medulla oblongata [nTPM]":"30.7","Brain RNA - midbrain [nTPM]":"27.9","Brain RNA - pons [nTPM]":"31.6","Brain RNA - spinal cord [nTPM]":"25.2","Brain RNA - thalamus [nTPM]":"28.2","Brain RNA - white matter [nTPM]":"36.9","Single Cell Type RNA - Adipocytes [nTPM]":"11.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"41.1","Single Cell Type RNA - B-cells [nTPM]":"22.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"35.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - dendritic cells [nTPM]":"16.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.0","Single Cell Type RNA - Early spermatids [nTPM]":"203.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"76.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.6","Single Cell Type RNA - Fibroblasts [nTPM]":"19.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.8","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"18.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"5.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"99.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"127.3","Single Cell Type RNA - Leydig cells [nTPM]":"38.8","Single Cell Type RNA - Macrophages [nTPM]":"6.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"7.6","Single Cell Type RNA - Muller glia cells [nTPM]":"28.1","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"198.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"166.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.5","Single Cell Type RNA - Paneth cells [nTPM]":"5.6","Single Cell Type RNA - Peritubular cells [nTPM]":"31.6","Single Cell Type RNA - Plasma cells [nTPM]":"25.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.4","Single Cell Type RNA - Spermatocytes [nTPM]":"78.3","Single Cell Type RNA - Spermatogonia [nTPM]":"37.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"17.8","Single Cell Type RNA - Theca cells [nTPM]":"12.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.7","Single Cell Type RNA - Urothelial cells [nTPM]":"10.9"},{"Gene":"KLC2","Gene synonym":["FLJ12387"],"Ensembl":"ENSG00000174996","Gene description":"Kinesin light chain 2","Uniprot":["Q9H0B6"],"Chromosome":"11","Position":"66257294-66267860","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"55.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040416","HPA040434"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm","Mitochondria"],"Antibody RRID":{"HPA040416":"AB_10795524","HPA040434":"AB_10795367"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.16e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.2","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"18.8","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"25.4","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"15.9","Tissue RNA - cerebellum [nTPM]":"33.0","Tissue RNA - cerebral cortex [nTPM]":"78.1","Tissue RNA - cervix [nTPM]":"27.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"28.5","Tissue RNA - duodenum [nTPM]":"9.8","Tissue RNA - endometrium 1 [nTPM]":"27.1","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"18.2","Tissue RNA - fallopian tube [nTPM]":"21.6","Tissue RNA - gallbladder [nTPM]":"8.9","Tissue RNA - heart muscle [nTPM]":"32.1","Tissue RNA - hippocampal formation [nTPM]":"26.6","Tissue RNA - hypothalamus [nTPM]":"12.7","Tissue RNA - kidney [nTPM]":"22.4","Tissue RNA - liver [nTPM]":"8.2","Tissue RNA - lung [nTPM]":"18.9","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"39.8","Tissue RNA - midbrain [nTPM]":"10.8","Tissue RNA - ovary [nTPM]":"24.6","Tissue RNA - pancreas [nTPM]":"15.5","Tissue RNA - parathyroid gland [nTPM]":"15.2","Tissue RNA - pituitary gland [nTPM]":"48.3","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"37.0","Tissue RNA - prostate [nTPM]":"28.7","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"28.4","Tissue RNA - salivary gland [nTPM]":"15.9","Tissue RNA - seminal vesicle [nTPM]":"16.0","Tissue RNA - skeletal muscle [nTPM]":"57.8","Tissue RNA - skin 1 [nTPM]":"18.3","Tissue RNA - small intestine [nTPM]":"16.3","Tissue RNA - smooth muscle [nTPM]":"11.2","Tissue RNA - spinal cord [nTPM]":"5.7","Tissue RNA - spleen [nTPM]":"13.7","Tissue RNA - stomach 1 [nTPM]":"20.2","Tissue RNA - testis [nTPM]":"32.2","Tissue RNA - thalamus [nTPM]":"23.1","Tissue RNA - thymus [nTPM]":"25.1","Tissue RNA - thyroid gland [nTPM]":"17.7","Tissue RNA - tongue [nTPM]":"14.2","Tissue RNA - tonsil [nTPM]":"6.4","Tissue RNA - urinary bladder [nTPM]":"27.2","Tissue RNA - vagina [nTPM]":"21.7","Tissue RNA - white matter [nTPM]":"35.8","Cell RNA - A-431 [nTPM]":"49.4","Cell RNA - A549 [nTPM]":"58.2","Cell RNA - AF22 [nTPM]":"28.3","Cell RNA - AN3-CA [nTPM]":"16.9","Cell RNA - ASC diff [nTPM]":"16.9","Cell RNA - ASC TERT1 [nTPM]":"13.5","Cell RNA - BEWO [nTPM]":"21.9","Cell RNA - BJ [nTPM]":"34.1","Cell RNA - BJ hTERT+ [nTPM]":"24.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.1","Cell RNA - CACO-2 [nTPM]":"31.9","Cell RNA - CAPAN-2 [nTPM]":"14.3","Cell RNA - Daudi [nTPM]":"21.3","Cell RNA - EFO-21 [nTPM]":"31.9","Cell RNA - fHDF\/TERT166 [nTPM]":"25.6","Cell RNA - GAMG [nTPM]":"43.9","Cell RNA - HaCaT [nTPM]":"40.7","Cell RNA - HAP1 [nTPM]":"29.3","Cell RNA - HBEC3-KT [nTPM]":"33.2","Cell RNA - HBF TERT88 [nTPM]":"11.4","Cell RNA - HDLM-2 [nTPM]":"35.7","Cell RNA - HEK 293 [nTPM]":"37.2","Cell RNA - HEL [nTPM]":"4.4","Cell RNA - HeLa [nTPM]":"48.0","Cell RNA - Hep G2 [nTPM]":"22.4","Cell RNA - HHSteC [nTPM]":"32.1","Cell RNA - HL-60 [nTPM]":"9.9","Cell RNA - HMC-1 [nTPM]":"22.7","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"42.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.1","Cell RNA - hTERT-HME1 [nTPM]":"32.8","Cell RNA - hTERT-RPE1 [nTPM]":"22.0","Cell RNA - HUVEC TERT2 [nTPM]":"16.1","Cell RNA - JURKAT [nTPM]":"26.2","Cell RNA - K-562 [nTPM]":"24.1","Cell RNA - Karpas-707 [nTPM]":"29.0","Cell RNA - LHCN-M2 [nTPM]":"27.8","Cell RNA - MCF7 [nTPM]":"69.2","Cell RNA - MOLT-4 [nTPM]":"56.8","Cell RNA - NB-4 [nTPM]":"15.0","Cell RNA - NTERA-2 [nTPM]":"27.8","Cell RNA - OE19 [nTPM]":"14.2","Cell RNA - PC-3 [nTPM]":"49.2","Cell RNA - REH [nTPM]":"21.4","Cell RNA - RH-30 [nTPM]":"14.6","Cell RNA - RPMI-8226 [nTPM]":"30.1","Cell RNA - RPTEC TERT1 [nTPM]":"27.2","Cell RNA - RT4 [nTPM]":"27.4","Cell RNA - SCLC-21H [nTPM]":"76.3","Cell RNA - SH-SY5Y [nTPM]":"37.5","Cell RNA - SiHa [nTPM]":"24.6","Cell RNA - SK-BR-3 [nTPM]":"22.1","Cell RNA - SK-MEL-30 [nTPM]":"41.3","Cell RNA - SuSa [nTPM]":"15.7","Cell RNA - T-47d [nTPM]":"36.3","Cell RNA - THP-1 [nTPM]":"6.7","Cell RNA - TIME [nTPM]":"26.8","Cell RNA - U-138 MG [nTPM]":"55.5","Cell RNA - U-2 OS [nTPM]":"49.8","Cell RNA - U-2197 [nTPM]":"68.2","Cell RNA - U-251 MG [nTPM]":"45.5","Cell RNA - U-266\/70 [nTPM]":"30.7","Cell RNA - U-266\/84 [nTPM]":"27.4","Cell RNA - U-698 [nTPM]":"11.9","Cell RNA - U-87 MG [nTPM]":"39.3","Cell RNA - U-937 [nTPM]":"6.7","Cell RNA - WM-115 [nTPM]":"22.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"3.1","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"18.8","Brain RNA - basal ganglia [nTPM]":"25.4","Brain RNA - cerebellum [nTPM]":"33.0","Brain RNA - cerebral cortex [nTPM]":"78.1","Brain RNA - hippocampal formation [nTPM]":"26.6","Brain RNA - hypothalamus [nTPM]":"12.7","Brain RNA - medulla oblongata [nTPM]":"39.8","Brain RNA - midbrain [nTPM]":"10.8","Brain RNA - pons [nTPM]":"37.0","Brain RNA - spinal cord [nTPM]":"5.7","Brain RNA - thalamus [nTPM]":"23.1","Brain RNA - white matter [nTPM]":"35.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"8.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"34.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"5.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - dendritic cells [nTPM]":"5.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"14.8","Single Cell Type RNA - Early spermatids [nTPM]":"10.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.2","Single Cell Type RNA - Fibroblasts [nTPM]":"6.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.2","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"2.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"14.6","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.1","Single Cell Type RNA - Paneth cells [nTPM]":"4.9","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.3","Single Cell Type RNA - Spermatocytes [nTPM]":"26.2","Single Cell Type RNA - Spermatogonia [nTPM]":"29.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - T-cells [nTPM]":"8.2","Single Cell Type RNA - Theca cells [nTPM]":"3.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.9","Single Cell Type RNA - Urothelial cells [nTPM]":"8.5"},{"Gene":"KLHL7","Gene synonym":["KLHL6","RP42","SBBI26"],"Ensembl":"ENSG00000122550","Gene description":"Kelch like family member 7","Uniprot":["Q8IXQ5"],"Chromosome":"7","Position":"23105758-23177914","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"50.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"560.6","Late spermatids":"242.7","Oligodendrocyte precursor cells":"168.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029491","HPA029492"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA029491":"AB_10599605","HPA029492":"AB_10600881"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.96e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.98e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.5","Tissue RNA - adrenal gland [nTPM]":"18.8","Tissue RNA - amygdala [nTPM]":"12.8","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"13.3","Tissue RNA - bone marrow [nTPM]":"12.4","Tissue RNA - breast [nTPM]":"13.0","Tissue RNA - cerebellum [nTPM]":"16.3","Tissue RNA - cerebral cortex [nTPM]":"15.9","Tissue RNA - cervix [nTPM]":"10.5","Tissue RNA - choroid plexus [nTPM]":"12.1","Tissue RNA - colon [nTPM]":"9.2","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"11.5","Tissue RNA - epididymis [nTPM]":"12.2","Tissue RNA - esophagus [nTPM]":"9.0","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"9.7","Tissue RNA - heart muscle [nTPM]":"50.8","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"13.1","Tissue RNA - kidney [nTPM]":"11.9","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"7.7","Tissue RNA - lymph node [nTPM]":"8.3","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"12.7","Tissue RNA - ovary [nTPM]":"11.8","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"10.8","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"8.6","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"10.1","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"14.9","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"9.1","Tissue RNA - skin 1 [nTPM]":"10.9","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"10.5","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"42.2","Tissue RNA - thalamus [nTPM]":"13.4","Tissue RNA - thymus [nTPM]":"12.4","Tissue RNA - thyroid gland [nTPM]":"9.2","Tissue RNA - tongue [nTPM]":"9.7","Tissue RNA - tonsil [nTPM]":"9.1","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"9.4","Tissue RNA - white matter [nTPM]":"14.7","Cell RNA - A-431 [nTPM]":"24.7","Cell RNA - A549 [nTPM]":"20.7","Cell RNA - AF22 [nTPM]":"55.7","Cell RNA - AN3-CA [nTPM]":"66.3","Cell RNA - ASC diff [nTPM]":"26.8","Cell RNA - ASC TERT1 [nTPM]":"23.2","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"21.3","Cell RNA - BJ hTERT+ [nTPM]":"31.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.6","Cell RNA - CACO-2 [nTPM]":"25.3","Cell RNA - CAPAN-2 [nTPM]":"17.5","Cell RNA - Daudi [nTPM]":"24.1","Cell RNA - EFO-21 [nTPM]":"16.8","Cell RNA - fHDF\/TERT166 [nTPM]":"26.2","Cell RNA - GAMG [nTPM]":"50.5","Cell RNA - HaCaT [nTPM]":"26.2","Cell RNA - HAP1 [nTPM]":"21.5","Cell RNA - HBEC3-KT [nTPM]":"15.0","Cell RNA - HBF TERT88 [nTPM]":"25.8","Cell RNA - HDLM-2 [nTPM]":"6.4","Cell RNA - HEK 293 [nTPM]":"15.5","Cell RNA - HEL [nTPM]":"15.9","Cell RNA - HeLa [nTPM]":"16.7","Cell RNA - Hep G2 [nTPM]":"32.9","Cell RNA - HHSteC [nTPM]":"20.0","Cell RNA - HL-60 [nTPM]":"32.5","Cell RNA - HMC-1 [nTPM]":"12.0","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"19.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.2","Cell RNA - hTERT-HME1 [nTPM]":"28.8","Cell RNA - hTERT-RPE1 [nTPM]":"24.2","Cell RNA - HUVEC TERT2 [nTPM]":"39.6","Cell RNA - JURKAT [nTPM]":"29.4","Cell RNA - K-562 [nTPM]":"28.3","Cell RNA - Karpas-707 [nTPM]":"25.5","Cell RNA - LHCN-M2 [nTPM]":"50.7","Cell RNA - MCF7 [nTPM]":"28.4","Cell RNA - MOLT-4 [nTPM]":"27.3","Cell RNA - NB-4 [nTPM]":"51.3","Cell RNA - NTERA-2 [nTPM]":"77.0","Cell RNA - OE19 [nTPM]":"16.7","Cell RNA - PC-3 [nTPM]":"24.5","Cell RNA - REH [nTPM]":"23.7","Cell RNA - RH-30 [nTPM]":"31.2","Cell RNA - RPMI-8226 [nTPM]":"22.2","Cell RNA - RPTEC TERT1 [nTPM]":"29.2","Cell RNA - RT4 [nTPM]":"21.0","Cell RNA - SCLC-21H [nTPM]":"33.5","Cell RNA - SH-SY5Y [nTPM]":"32.5","Cell RNA - SiHa [nTPM]":"46.2","Cell RNA - SK-BR-3 [nTPM]":"22.7","Cell RNA - SK-MEL-30 [nTPM]":"23.3","Cell RNA - SuSa [nTPM]":"33.9","Cell RNA - T-47d [nTPM]":"18.9","Cell RNA - THP-1 [nTPM]":"16.9","Cell RNA - TIME [nTPM]":"17.0","Cell RNA - U-138 MG [nTPM]":"25.7","Cell RNA - U-2 OS [nTPM]":"26.6","Cell RNA - U-2197 [nTPM]":"56.9","Cell RNA - U-251 MG [nTPM]":"25.7","Cell RNA - U-266\/70 [nTPM]":"39.9","Cell RNA - U-266\/84 [nTPM]":"35.3","Cell RNA - U-698 [nTPM]":"58.6","Cell RNA - U-87 MG [nTPM]":"17.0","Cell RNA - U-937 [nTPM]":"33.8","Cell RNA - WM-115 [nTPM]":"31.5","Blood RNA - basophil [nTPM]":"44.1","Blood RNA - classical monocyte [nTPM]":"15.3","Blood RNA - eosinophil [nTPM]":"67.2","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"17.9","Blood RNA - MAIT T-cell [nTPM]":"13.7","Blood RNA - memory B-cell [nTPM]":"9.2","Blood RNA - memory CD4 T-cell [nTPM]":"13.8","Blood RNA - memory CD8 T-cell [nTPM]":"12.3","Blood RNA - myeloid DC [nTPM]":"11.1","Blood RNA - naive B-cell [nTPM]":"11.9","Blood RNA - naive CD4 T-cell [nTPM]":"10.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.0","Blood RNA - neutrophil [nTPM]":"14.4","Blood RNA - NK-cell [nTPM]":"9.5","Blood RNA - non-classical monocyte [nTPM]":"15.8","Blood RNA - plasmacytoid DC [nTPM]":"8.0","Blood RNA - T-reg [nTPM]":"16.7","Blood RNA - total PBMC [nTPM]":"12.6","Brain RNA - amygdala [nTPM]":"12.8","Brain RNA - basal ganglia [nTPM]":"13.3","Brain RNA - cerebellum [nTPM]":"16.3","Brain RNA - cerebral cortex [nTPM]":"15.9","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"13.1","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"12.7","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"13.4","Brain RNA - white matter [nTPM]":"14.7","Single Cell Type RNA - Adipocytes [nTPM]":"12.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"45.7","Single Cell Type RNA - B-cells [nTPM]":"13.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"23.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"101.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"11.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.7","Single Cell Type RNA - dendritic cells [nTPM]":"14.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"17.7","Single Cell Type RNA - Early spermatids [nTPM]":"560.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.7","Single Cell Type RNA - Endothelial cells [nTPM]":"15.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"25.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"74.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.1","Single Cell Type RNA - Fibroblasts [nTPM]":"19.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.2","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"16.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.7","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"75.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.0","Single Cell Type RNA - Langerhans cells [nTPM]":"17.2","Single Cell Type RNA - Late spermatids [nTPM]":"242.7","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"12.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"13.4","Single Cell Type RNA - Muller glia cells [nTPM]":"30.3","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"168.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"45.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"12.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.9","Single Cell Type RNA - Spermatocytes [nTPM]":"83.7","Single Cell Type RNA - Spermatogonia [nTPM]":"19.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.7","Single Cell Type RNA - T-cells [nTPM]":"17.2","Single Cell Type RNA - Theca cells [nTPM]":"12.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.0","Single Cell Type RNA - Urothelial cells [nTPM]":"24.0"},{"Gene":"KMT2B","Gene synonym":["CXXC10","HRX2","KIAA0304","MLL1B","MLL2","MLL4","TRX2","WBP7"],"Ensembl":"ENSG00000272333","Gene description":"Lysine methyltransferase 2B","Uniprot":["Q9UMN6"],"Chromosome":"19","Position":"35717973-35738878","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"64.5","Rod photoreceptor cells":"71.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006487"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA006487":"AB_1080587"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"15.4","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"15.7","Tissue RNA - bone marrow [nTPM]":"14.3","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"17.2","Tissue RNA - cerebral cortex [nTPM]":"22.9","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"13.6","Tissue RNA - duodenum [nTPM]":"9.8","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"12.8","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"14.8","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"12.1","Tissue RNA - lymph node [nTPM]":"14.5","Tissue RNA - medulla oblongata [nTPM]":"15.4","Tissue RNA - midbrain [nTPM]":"14.4","Tissue RNA - ovary [nTPM]":"16.1","Tissue RNA - pancreas [nTPM]":"16.0","Tissue RNA - parathyroid gland [nTPM]":"5.1","Tissue RNA - pituitary gland [nTPM]":"14.5","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"14.7","Tissue RNA - prostate [nTPM]":"13.4","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"5.8","Tissue RNA - salivary gland [nTPM]":"13.3","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"16.1","Tissue RNA - skin 1 [nTPM]":"18.8","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"12.4","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"12.7","Tissue RNA - testis [nTPM]":"22.5","Tissue RNA - thalamus [nTPM]":"15.9","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"16.6","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"6.8","Tissue RNA - urinary bladder [nTPM]":"12.6","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"16.0","Cell RNA - A-431 [nTPM]":"16.7","Cell RNA - A549 [nTPM]":"36.7","Cell RNA - AF22 [nTPM]":"11.1","Cell RNA - AN3-CA [nTPM]":"17.3","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"4.3","Cell RNA - BEWO [nTPM]":"11.0","Cell RNA - BJ [nTPM]":"6.7","Cell RNA - BJ hTERT+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"25.3","Cell RNA - CAPAN-2 [nTPM]":"7.4","Cell RNA - Daudi [nTPM]":"15.5","Cell RNA - EFO-21 [nTPM]":"11.8","Cell RNA - fHDF\/TERT166 [nTPM]":"5.1","Cell RNA - GAMG [nTPM]":"8.5","Cell RNA - HaCaT [nTPM]":"10.8","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"5.2","Cell RNA - HBF TERT88 [nTPM]":"4.2","Cell RNA - HDLM-2 [nTPM]":"21.2","Cell RNA - HEK 293 [nTPM]":"13.6","Cell RNA - HEL [nTPM]":"29.7","Cell RNA - HeLa [nTPM]":"20.2","Cell RNA - Hep G2 [nTPM]":"24.4","Cell RNA - HHSteC [nTPM]":"8.6","Cell RNA - HL-60 [nTPM]":"17.4","Cell RNA - HMC-1 [nTPM]":"26.1","Cell RNA - HSkMC [nTPM]":"6.9","Cell RNA - hTCEpi [nTPM]":"9.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.9","Cell RNA - hTERT-HME1 [nTPM]":"10.7","Cell RNA - hTERT-RPE1 [nTPM]":"6.9","Cell RNA - HUVEC TERT2 [nTPM]":"5.7","Cell RNA - JURKAT [nTPM]":"13.5","Cell RNA - K-562 [nTPM]":"22.5","Cell RNA - Karpas-707 [nTPM]":"15.8","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"34.1","Cell RNA - MOLT-4 [nTPM]":"15.9","Cell RNA - NB-4 [nTPM]":"24.4","Cell RNA - NTERA-2 [nTPM]":"12.0","Cell RNA - OE19 [nTPM]":"18.8","Cell RNA - PC-3 [nTPM]":"9.2","Cell RNA - REH [nTPM]":"19.8","Cell RNA - RH-30 [nTPM]":"8.9","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"7.8","Cell RNA - RT4 [nTPM]":"21.3","Cell RNA - SCLC-21H [nTPM]":"14.0","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"13.5","Cell RNA - SK-BR-3 [nTPM]":"20.6","Cell RNA - SK-MEL-30 [nTPM]":"11.3","Cell RNA - SuSa [nTPM]":"7.9","Cell RNA - T-47d [nTPM]":"11.8","Cell RNA - THP-1 [nTPM]":"21.3","Cell RNA - TIME [nTPM]":"12.5","Cell RNA - U-138 MG [nTPM]":"16.3","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"10.5","Cell RNA - U-251 MG [nTPM]":"17.4","Cell RNA - U-266\/70 [nTPM]":"22.2","Cell RNA - U-266\/84 [nTPM]":"15.7","Cell RNA - U-698 [nTPM]":"12.4","Cell RNA - U-87 MG [nTPM]":"8.5","Cell RNA - U-937 [nTPM]":"18.8","Cell RNA - WM-115 [nTPM]":"12.2","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"15.4","Brain RNA - basal ganglia [nTPM]":"15.7","Brain RNA - cerebellum [nTPM]":"17.2","Brain RNA - cerebral cortex [nTPM]":"22.9","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"14.8","Brain RNA - medulla oblongata [nTPM]":"15.4","Brain RNA - midbrain [nTPM]":"14.4","Brain RNA - pons [nTPM]":"14.7","Brain RNA - spinal cord [nTPM]":"12.4","Brain RNA - thalamus [nTPM]":"15.9","Brain RNA - white matter [nTPM]":"16.0","Single Cell Type RNA - Adipocytes [nTPM]":"24.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.4","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"18.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"64.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"6.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"27.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.6","Single Cell Type RNA - Endothelial cells [nTPM]":"15.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.0","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"30.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"11.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.4","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.7","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"13.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"9.5","Single Cell Type RNA - Muller glia cells [nTPM]":"25.7","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.4","Single Cell Type RNA - Paneth cells [nTPM]":"16.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"17.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"71.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"26.5","Single Cell Type RNA - Spermatogonia [nTPM]":"38.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - T-cells [nTPM]":"20.6","Single Cell Type RNA - Theca cells [nTPM]":"30.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.3","Single Cell Type RNA - Urothelial cells [nTPM]":"14.8"},{"Gene":"KRT12","Gene synonym":["K12"],"Ensembl":"ENSG00000187242","Gene description":"Keratin 12","Uniprot":["Q99456"],"Chromosome":"17","Position":"40861303-40867223","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Corneal dystrophy","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"1.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Distal enterocytes":"3.9","Paneth cells":"12.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055217","HPA055835"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055217":"AB_2682742","HPA055835":"AB_2682935"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"12.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KRT3","Gene synonym":["CK3","K3"],"Ensembl":"ENSG00000186442","Gene description":"Keratin 3","Uniprot":["P12035"],"Chromosome":"12","Position":"52789685-52796117","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"esophagus":"3.0","salivary gland":"10.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"cervical cancer":"0.7","head and neck cancer":"2.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"HaCaT":"9.4","HMC-1":"5.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"1.7"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"10.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"5.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"L1CAM","Gene synonym":["CD171","HSAS","HSAS1","MASA","MIC5","S10","SPG1"],"Ensembl":"ENSG00000198910","Gene description":"L1 cell adhesion molecule","Uniprot":["P32004"],"Chromosome":"X","Position":"153861514-153886173","Protein class":["CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Hirschsprung disease","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"42.8","intestine":"48.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"84.6","Excitatory neurons":"23.7","Horizontal cells":"33.7","Inhibitory neurons":"23.3","Melanocytes":"44.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"34.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"372.4","BJ hTERT+ SV40 Large T+ RasG12V":"200.8","HeLa":"258.1","RH-30":"162.6","RPTEC TERT1":"218.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010896"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"67000000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010896":"AB_609903"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.51e-10"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.81e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.36e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.17e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.5","Tissue RNA - adrenal gland [nTPM]":"27.2","Tissue RNA - amygdala [nTPM]":"20.4","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"23.0","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"23.0","Tissue RNA - cerebral cortex [nTPM]":"42.8","Tissue RNA - cervix [nTPM]":"8.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"48.5","Tissue RNA - duodenum [nTPM]":"4.2","Tissue RNA - endometrium 1 [nTPM]":"2.4","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"3.4","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"12.1","Tissue RNA - hippocampal formation [nTPM]":"12.6","Tissue RNA - hypothalamus [nTPM]":"42.4","Tissue RNA - kidney [nTPM]":"18.5","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"15.7","Tissue RNA - salivary gland [nTPM]":"4.8","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"9.2","Tissue RNA - small intestine [nTPM]":"13.0","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"11.3","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"6.1","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"13.2","Cell RNA - A-431 [nTPM]":"95.2","Cell RNA - A549 [nTPM]":"7.2","Cell RNA - AF22 [nTPM]":"27.6","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"11.8","Cell RNA - BJ [nTPM]":"131.6","Cell RNA - BJ hTERT+ [nTPM]":"372.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"123.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"200.8","Cell RNA - CACO-2 [nTPM]":"37.8","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"121.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"103.2","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"3.5","Cell RNA - HBEC3-KT [nTPM]":"2.3","Cell RNA - HBF TERT88 [nTPM]":"64.1","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"258.1","Cell RNA - Hep G2 [nTPM]":"6.1","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"20.4","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.7","Cell RNA - hTERT-HME1 [nTPM]":"12.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"127.9","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"2.6","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"4.7","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"162.6","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"218.4","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"81.4","Cell RNA - SH-SY5Y [nTPM]":"53.0","Cell RNA - SiHa [nTPM]":"73.4","Cell RNA - SK-BR-3 [nTPM]":"64.2","Cell RNA - SK-MEL-30 [nTPM]":"54.1","Cell RNA - SuSa [nTPM]":"61.0","Cell RNA - T-47d [nTPM]":"6.7","Cell RNA - THP-1 [nTPM]":"1.7","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"52.6","Cell RNA - U-2197 [nTPM]":"5.8","Cell RNA - U-251 MG [nTPM]":"63.7","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"1.6","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"105.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"20.4","Brain RNA - basal ganglia [nTPM]":"23.0","Brain RNA - cerebellum [nTPM]":"23.0","Brain RNA - cerebral cortex [nTPM]":"42.8","Brain RNA - hippocampal formation [nTPM]":"12.6","Brain RNA - hypothalamus [nTPM]":"42.4","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"13.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"84.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"LCA5","Gene synonym":["C6orf152"],"Ensembl":"ENSG00000135338","Gene description":"Lebercilin LCA5","Uniprot":["Q86VQ0"],"Chromosome":"6","Position":"79484991-79537458","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"52.6","Respiratory ciliated cells":"89.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"14.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029053","HPA029055"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029053":"AB_10602020","HPA029055":"AB_2672889"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.2","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"5.0","Tissue RNA - cervix [nTPM]":"4.2","Tissue RNA - choroid plexus [nTPM]":"16.9","Tissue RNA - colon [nTPM]":"2.5","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"5.4","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"4.6","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"4.0","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"7.3","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"17.2","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"5.1","Tissue RNA - prostate [nTPM]":"3.9","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"13.7","Tissue RNA - salivary gland [nTPM]":"5.5","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"6.9","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"1.7","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"3.9","Cell RNA - AN3-CA [nTPM]":"2.2","Cell RNA - ASC diff [nTPM]":"4.8","Cell RNA - ASC TERT1 [nTPM]":"5.3","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"3.0","Cell RNA - BJ hTERT+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.7","Cell RNA - CACO-2 [nTPM]":"9.9","Cell RNA - CAPAN-2 [nTPM]":"1.9","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"3.9","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"3.4","Cell RNA - HaCaT [nTPM]":"1.8","Cell RNA - HAP1 [nTPM]":"2.9","Cell RNA - HBEC3-KT [nTPM]":"1.8","Cell RNA - HBF TERT88 [nTPM]":"3.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"14.6","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"5.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"5.0","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.1","Cell RNA - hTERT-HME1 [nTPM]":"4.0","Cell RNA - hTERT-RPE1 [nTPM]":"7.0","Cell RNA - HUVEC TERT2 [nTPM]":"5.6","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"2.3","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"3.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"6.8","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"3.9","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"2.9","Cell RNA - SH-SY5Y [nTPM]":"3.5","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"3.9","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"2.6","Cell RNA - U-266\/70 [nTPM]":"3.7","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"5.0","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"4.6","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"5.1","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"6.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"12.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"17.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"15.9","Single Cell Type RNA - Early spermatids [nTPM]":"17.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"52.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"14.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"6.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"13.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"89.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.1","Single Cell Type RNA - Spermatocytes [nTPM]":"18.0","Single Cell Type RNA - Spermatogonia [nTPM]":"11.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.3","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"8.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"9.5"},{"Gene":"LEMD2","Gene synonym":["dJ482C21.1","LEM2","NET25"],"Ensembl":"ENSG00000161904","Gene description":"LEM domain nuclear envelope protein 2","Uniprot":["Q8NC56"],"Chromosome":"6","Position":"33771202-33789130","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017340"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA017340":"AB_2296925"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"40.5","Tissue RNA - adrenal gland [nTPM]":"45.8","Tissue RNA - amygdala [nTPM]":"46.0","Tissue RNA - appendix [nTPM]":"35.0","Tissue RNA - basal ganglia [nTPM]":"47.9","Tissue RNA - bone marrow [nTPM]":"63.3","Tissue RNA - breast [nTPM]":"39.6","Tissue RNA - cerebellum [nTPM]":"53.1","Tissue RNA - cerebral cortex [nTPM]":"50.8","Tissue RNA - cervix [nTPM]":"52.6","Tissue RNA - choroid plexus [nTPM]":"44.6","Tissue RNA - colon [nTPM]":"45.3","Tissue RNA - duodenum [nTPM]":"31.9","Tissue RNA - endometrium 1 [nTPM]":"44.1","Tissue RNA - epididymis [nTPM]":"29.7","Tissue RNA - esophagus [nTPM]":"50.2","Tissue RNA - fallopian tube [nTPM]":"45.9","Tissue RNA - gallbladder [nTPM]":"30.0","Tissue RNA - heart muscle [nTPM]":"46.7","Tissue RNA - hippocampal formation [nTPM]":"43.9","Tissue RNA - hypothalamus [nTPM]":"44.0","Tissue RNA - kidney [nTPM]":"51.5","Tissue RNA - liver [nTPM]":"49.9","Tissue RNA - lung [nTPM]":"51.2","Tissue RNA - lymph node [nTPM]":"45.4","Tissue RNA - medulla oblongata [nTPM]":"52.0","Tissue RNA - midbrain [nTPM]":"47.0","Tissue RNA - ovary [nTPM]":"53.7","Tissue RNA - pancreas [nTPM]":"54.5","Tissue RNA - parathyroid gland [nTPM]":"39.3","Tissue RNA - pituitary gland [nTPM]":"56.5","Tissue RNA - placenta [nTPM]":"38.5","Tissue RNA - pons [nTPM]":"47.9","Tissue RNA - prostate [nTPM]":"51.9","Tissue RNA - rectum [nTPM]":"30.0","Tissue RNA - retina [nTPM]":"29.7","Tissue RNA - salivary gland [nTPM]":"43.3","Tissue RNA - seminal vesicle [nTPM]":"31.3","Tissue RNA - skeletal muscle [nTPM]":"37.4","Tissue RNA - skin 1 [nTPM]":"51.8","Tissue RNA - small intestine [nTPM]":"50.1","Tissue RNA - smooth muscle [nTPM]":"30.4","Tissue RNA - spinal cord [nTPM]":"46.3","Tissue RNA - spleen [nTPM]":"70.1","Tissue RNA - stomach 1 [nTPM]":"44.9","Tissue RNA - testis [nTPM]":"45.5","Tissue RNA - thalamus [nTPM]":"47.2","Tissue RNA - thymus [nTPM]":"46.1","Tissue RNA - thyroid gland [nTPM]":"53.0","Tissue RNA - tongue [nTPM]":"28.1","Tissue RNA - tonsil [nTPM]":"41.6","Tissue RNA - urinary bladder [nTPM]":"43.8","Tissue RNA - vagina [nTPM]":"44.9","Tissue RNA - white matter [nTPM]":"54.4","Cell RNA - A-431 [nTPM]":"36.6","Cell RNA - A549 [nTPM]":"40.5","Cell RNA - AF22 [nTPM]":"67.3","Cell RNA - AN3-CA [nTPM]":"66.1","Cell RNA - ASC diff [nTPM]":"37.6","Cell RNA - ASC TERT1 [nTPM]":"40.3","Cell RNA - BEWO [nTPM]":"50.9","Cell RNA - BJ [nTPM]":"39.1","Cell RNA - BJ hTERT+ [nTPM]":"59.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"50.9","Cell RNA - CACO-2 [nTPM]":"30.6","Cell RNA - CAPAN-2 [nTPM]":"37.8","Cell RNA - Daudi [nTPM]":"33.8","Cell RNA - EFO-21 [nTPM]":"53.5","Cell RNA - fHDF\/TERT166 [nTPM]":"55.6","Cell RNA - GAMG [nTPM]":"136.7","Cell RNA - HaCaT [nTPM]":"62.0","Cell RNA - HAP1 [nTPM]":"39.4","Cell RNA - HBEC3-KT [nTPM]":"52.1","Cell RNA - HBF TERT88 [nTPM]":"34.0","Cell RNA - HDLM-2 [nTPM]":"35.9","Cell RNA - HEK 293 [nTPM]":"36.6","Cell RNA - HEL [nTPM]":"12.7","Cell RNA - HeLa [nTPM]":"45.8","Cell RNA - Hep G2 [nTPM]":"40.3","Cell RNA - HHSteC [nTPM]":"78.4","Cell RNA - HL-60 [nTPM]":"26.1","Cell RNA - HMC-1 [nTPM]":"42.6","Cell RNA - HSkMC [nTPM]":"44.3","Cell RNA - hTCEpi [nTPM]":"96.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"51.6","Cell RNA - hTERT-HME1 [nTPM]":"88.1","Cell RNA - hTERT-RPE1 [nTPM]":"80.0","Cell RNA - HUVEC TERT2 [nTPM]":"52.8","Cell RNA - JURKAT [nTPM]":"43.9","Cell RNA - K-562 [nTPM]":"36.3","Cell RNA - Karpas-707 [nTPM]":"38.3","Cell RNA - LHCN-M2 [nTPM]":"42.8","Cell RNA - MCF7 [nTPM]":"30.8","Cell RNA - MOLT-4 [nTPM]":"48.6","Cell RNA - NB-4 [nTPM]":"64.1","Cell RNA - NTERA-2 [nTPM]":"39.2","Cell RNA - OE19 [nTPM]":"53.5","Cell RNA - PC-3 [nTPM]":"23.2","Cell RNA - REH [nTPM]":"31.8","Cell RNA - RH-30 [nTPM]":"27.8","Cell RNA - RPMI-8226 [nTPM]":"28.3","Cell RNA - RPTEC TERT1 [nTPM]":"52.0","Cell RNA - RT4 [nTPM]":"50.5","Cell RNA - SCLC-21H [nTPM]":"47.8","Cell RNA - SH-SY5Y [nTPM]":"37.8","Cell RNA - SiHa [nTPM]":"23.4","Cell RNA - SK-BR-3 [nTPM]":"74.0","Cell RNA - SK-MEL-30 [nTPM]":"52.6","Cell RNA - SuSa [nTPM]":"68.0","Cell RNA - T-47d [nTPM]":"49.5","Cell RNA - THP-1 [nTPM]":"70.7","Cell RNA - TIME [nTPM]":"24.6","Cell RNA - U-138 MG [nTPM]":"67.8","Cell RNA - U-2 OS [nTPM]":"26.3","Cell RNA - U-2197 [nTPM]":"36.6","Cell RNA - U-251 MG [nTPM]":"46.5","Cell RNA - U-266\/70 [nTPM]":"49.8","Cell RNA - U-266\/84 [nTPM]":"43.0","Cell RNA - U-698 [nTPM]":"24.0","Cell RNA - U-87 MG [nTPM]":"26.7","Cell RNA - U-937 [nTPM]":"40.3","Cell RNA - WM-115 [nTPM]":"83.0","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.3","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"46.0","Brain RNA - basal ganglia [nTPM]":"47.9","Brain RNA - cerebellum [nTPM]":"53.1","Brain RNA - cerebral cortex [nTPM]":"50.8","Brain RNA - hippocampal formation [nTPM]":"43.9","Brain RNA - hypothalamus [nTPM]":"44.0","Brain RNA - medulla oblongata [nTPM]":"52.0","Brain RNA - midbrain [nTPM]":"47.0","Brain RNA - pons [nTPM]":"47.9","Brain RNA - spinal cord [nTPM]":"46.3","Brain RNA - thalamus [nTPM]":"47.2","Brain RNA - white matter [nTPM]":"54.4","Single Cell Type RNA - Adipocytes [nTPM]":"19.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"17.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"18.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"5.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.9","Single Cell Type RNA - dendritic cells [nTPM]":"18.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.4","Single Cell Type RNA - Early spermatids [nTPM]":"24.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.6","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"16.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.5","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.7","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"14.5","Single Cell Type RNA - Langerhans cells [nTPM]":"12.4","Single Cell Type RNA - Late spermatids [nTPM]":"44.2","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"9.4","Single Cell Type RNA - Muller glia cells [nTPM]":"14.0","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.2","Single Cell Type RNA - Paneth cells [nTPM]":"20.1","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"11.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.2","Single Cell Type RNA - Spermatocytes [nTPM]":"24.6","Single Cell Type RNA - Spermatogonia [nTPM]":"7.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.8","Single Cell Type RNA - T-cells [nTPM]":"15.2","Single Cell Type RNA - Theca cells [nTPM]":"12.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.9","Single Cell Type RNA - Urothelial cells [nTPM]":"13.2"},{"Gene":"LGI1","Gene synonym":["EPITEMPIN","EPT","ETL1","IB1099"],"Ensembl":"ENSG00000108231","Gene description":"Leucine rich glioma inactivated 1","Uniprot":["O95970"],"Chromosome":"10","Position":"93757840-93806272","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"39.7","choroid plexus":"44.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"242.9","Excitatory neurons":"57.1","Inhibitory neurons":"74.7","Oligodendrocyte precursor cells":"28.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"1.8","testis cancer":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"9.4","CACO-2":"2.0","NTERA-2":"6.1","SuSa":"3.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"26.8","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"31.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"23.8","Tissue RNA - cerebral cortex [nTPM]":"39.7","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"44.7","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"4.3","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"29.2","Tissue RNA - hypothalamus [nTPM]":"22.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"29.9","Tissue RNA - midbrain [nTPM]":"24.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"32.9","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.5","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"23.7","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.8","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"26.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"25.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"9.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"6.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.4","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"26.8","Brain RNA - basal ganglia [nTPM]":"31.5","Brain RNA - cerebellum [nTPM]":"23.8","Brain RNA - cerebral cortex [nTPM]":"39.7","Brain RNA - hippocampal formation [nTPM]":"29.2","Brain RNA - hypothalamus [nTPM]":"22.6","Brain RNA - medulla oblongata [nTPM]":"29.9","Brain RNA - midbrain [nTPM]":"24.2","Brain RNA - pons [nTPM]":"32.9","Brain RNA - spinal cord [nTPM]":"23.7","Brain RNA - thalamus [nTPM]":"26.7","Brain RNA - white matter [nTPM]":"25.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"242.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"10.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"57.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"6.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"LHFPL5","Gene synonym":["DFNB67","dJ510O8.8","MGC33835","Tmhs"],"Ensembl":"ENSG00000197753","Gene description":"LHFPL tetraspan subfamily member 5","Uniprot":["Q8TAF8"],"Chromosome":"6","Position":"35797206-35845397","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"18.8","epididymis":"12.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"13.5","Excitatory neurons":"8.0","Glandular and luminal cells":"2.8","Inhibitory neurons":"3.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029421","HPA055110"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029421":null,"HPA055110":"AB_2682697"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"2.7","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"18.8","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"5.6","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"8.2","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"7.6","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"3.0","Cell RNA - AN3-CA [nTPM]":"3.1","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"4.6","Cell RNA - BJ [nTPM]":"1.6","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"2.7","Cell RNA - CAPAN-2 [nTPM]":"2.0","Cell RNA - Daudi [nTPM]":"3.6","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"1.9","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"3.2","Cell RNA - HeLa [nTPM]":"5.3","Cell RNA - Hep G2 [nTPM]":"4.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"2.2","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"3.6","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"5.1","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"6.2","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"2.2","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"2.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"5.6","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"2.3","Cell RNA - SK-MEL-30 [nTPM]":"1.0","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"2.4","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"3.1","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"2.5","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"3.2","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"3.1","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"3.6","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"LIM2","Gene synonym":["MP17","MP19"],"Ensembl":"ENSG00000105370","Gene description":"Lens intrinsic membrane protein 2","Uniprot":["P55344"],"Chromosome":"19","Position":"51379909-51387974","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"NK-cells":"20.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"40","RNA cancer specific FPKM":{"testis cancer":"18.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"gdT-cell":"11.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"T-cells":"11.3"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"11.3","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"LITAF","Gene synonym":["FLJ38636","PIG7","SIMPLE","TP53I7"],"Ensembl":"ENSG00000189067","Gene description":"Lipopolysaccharide induced TNF factor","Uniprot":["Q99732"],"Chromosome":"16","Position":"11547722-11636381","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"701.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"2578.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2578.1"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006960"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"HPA006960":"AB_1079254"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.25e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"139.3","Tissue RNA - adrenal gland [nTPM]":"43.7","Tissue RNA - amygdala [nTPM]":"53.5","Tissue RNA - appendix [nTPM]":"165.8","Tissue RNA - basal ganglia [nTPM]":"81.9","Tissue RNA - bone marrow [nTPM]":"207.0","Tissue RNA - breast [nTPM]":"95.5","Tissue RNA - cerebellum [nTPM]":"79.6","Tissue RNA - cerebral cortex [nTPM]":"70.0","Tissue RNA - cervix [nTPM]":"121.2","Tissue RNA - choroid plexus [nTPM]":"70.5","Tissue RNA - colon [nTPM]":"121.1","Tissue RNA - duodenum [nTPM]":"46.3","Tissue RNA - endometrium 1 [nTPM]":"100.5","Tissue RNA - epididymis [nTPM]":"77.8","Tissue RNA - esophagus [nTPM]":"62.7","Tissue RNA - fallopian tube [nTPM]":"108.2","Tissue RNA - gallbladder [nTPM]":"114.1","Tissue RNA - heart muscle [nTPM]":"63.9","Tissue RNA - hippocampal formation [nTPM]":"52.2","Tissue RNA - hypothalamus [nTPM]":"63.0","Tissue RNA - kidney [nTPM]":"182.3","Tissue RNA - liver [nTPM]":"107.7","Tissue RNA - lung [nTPM]":"192.1","Tissue RNA - lymph node [nTPM]":"112.3","Tissue RNA - medulla oblongata [nTPM]":"94.0","Tissue RNA - midbrain [nTPM]":"79.4","Tissue RNA - ovary [nTPM]":"67.6","Tissue RNA - pancreas [nTPM]":"64.6","Tissue RNA - parathyroid gland [nTPM]":"56.5","Tissue RNA - pituitary gland [nTPM]":"39.0","Tissue RNA - placenta [nTPM]":"71.3","Tissue RNA - pons [nTPM]":"92.7","Tissue RNA - prostate [nTPM]":"105.9","Tissue RNA - rectum [nTPM]":"116.1","Tissue RNA - retina [nTPM]":"63.9","Tissue RNA - salivary gland [nTPM]":"116.4","Tissue RNA - seminal vesicle [nTPM]":"83.4","Tissue RNA - skeletal muscle [nTPM]":"36.3","Tissue RNA - skin 1 [nTPM]":"71.6","Tissue RNA - small intestine [nTPM]":"57.9","Tissue RNA - smooth muscle [nTPM]":"93.5","Tissue RNA - spinal cord [nTPM]":"77.3","Tissue RNA - spleen [nTPM]":"119.6","Tissue RNA - stomach 1 [nTPM]":"70.7","Tissue RNA - testis [nTPM]":"10.6","Tissue RNA - thalamus [nTPM]":"77.6","Tissue RNA - thymus [nTPM]":"68.6","Tissue RNA - thyroid gland [nTPM]":"116.8","Tissue RNA - tongue [nTPM]":"37.6","Tissue RNA - tonsil [nTPM]":"123.7","Tissue RNA - urinary bladder [nTPM]":"214.1","Tissue RNA - vagina [nTPM]":"83.1","Tissue RNA - white matter [nTPM]":"109.4","Cell RNA - A-431 [nTPM]":"79.2","Cell RNA - A549 [nTPM]":"157.8","Cell RNA - AF22 [nTPM]":"89.4","Cell RNA - AN3-CA [nTPM]":"43.8","Cell RNA - ASC diff [nTPM]":"13.9","Cell RNA - ASC TERT1 [nTPM]":"11.0","Cell RNA - BEWO [nTPM]":"90.7","Cell RNA - BJ [nTPM]":"100.2","Cell RNA - BJ hTERT+ [nTPM]":"309.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"93.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"139.1","Cell RNA - CACO-2 [nTPM]":"62.6","Cell RNA - CAPAN-2 [nTPM]":"206.3","Cell RNA - Daudi [nTPM]":"39.9","Cell RNA - EFO-21 [nTPM]":"126.8","Cell RNA - fHDF\/TERT166 [nTPM]":"86.1","Cell RNA - GAMG [nTPM]":"108.7","Cell RNA - HaCaT [nTPM]":"95.5","Cell RNA - HAP1 [nTPM]":"40.1","Cell RNA - HBEC3-KT [nTPM]":"186.4","Cell RNA - HBF TERT88 [nTPM]":"88.4","Cell RNA - HDLM-2 [nTPM]":"304.2","Cell RNA - HEK 293 [nTPM]":"45.8","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"117.1","Cell RNA - Hep G2 [nTPM]":"310.3","Cell RNA - HHSteC [nTPM]":"212.9","Cell RNA - HL-60 [nTPM]":"12.5","Cell RNA - HMC-1 [nTPM]":"12.9","Cell RNA - HSkMC [nTPM]":"35.0","Cell RNA - hTCEpi [nTPM]":"320.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"79.6","Cell RNA - hTERT-HME1 [nTPM]":"210.7","Cell RNA - hTERT-RPE1 [nTPM]":"84.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"2.7","Cell RNA - K-562 [nTPM]":"25.3","Cell RNA - Karpas-707 [nTPM]":"149.5","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"75.8","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"183.3","Cell RNA - NTERA-2 [nTPM]":"146.4","Cell RNA - OE19 [nTPM]":"104.0","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"12.1","Cell RNA - RH-30 [nTPM]":"19.6","Cell RNA - RPMI-8226 [nTPM]":"228.2","Cell RNA - RPTEC TERT1 [nTPM]":"79.0","Cell RNA - RT4 [nTPM]":"110.4","Cell RNA - SCLC-21H [nTPM]":"22.2","Cell RNA - SH-SY5Y [nTPM]":"68.0","Cell RNA - SiHa [nTPM]":"172.9","Cell RNA - SK-BR-3 [nTPM]":"219.4","Cell RNA - SK-MEL-30 [nTPM]":"183.9","Cell RNA - SuSa [nTPM]":"136.3","Cell RNA - T-47d [nTPM]":"122.5","Cell RNA - THP-1 [nTPM]":"66.7","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"38.7","Cell RNA - U-2 OS [nTPM]":"65.3","Cell RNA - U-2197 [nTPM]":"23.0","Cell RNA - U-251 MG [nTPM]":"24.2","Cell RNA - U-266\/70 [nTPM]":"59.2","Cell RNA - U-266\/84 [nTPM]":"140.6","Cell RNA - U-698 [nTPM]":"100.5","Cell RNA - U-87 MG [nTPM]":"45.1","Cell RNA - U-937 [nTPM]":"95.8","Cell RNA - WM-115 [nTPM]":"225.5","Blood RNA - basophil [nTPM]":"508.8","Blood RNA - classical monocyte [nTPM]":"149.5","Blood RNA - eosinophil [nTPM]":"284.0","Blood RNA - gdT-cell [nTPM]":"459.6","Blood RNA - intermediate monocyte [nTPM]":"130.2","Blood RNA - MAIT T-cell [nTPM]":"277.2","Blood RNA - memory B-cell [nTPM]":"174.0","Blood RNA - memory CD4 T-cell [nTPM]":"284.0","Blood RNA - memory CD8 T-cell [nTPM]":"412.7","Blood RNA - myeloid DC [nTPM]":"178.0","Blood RNA - naive B-cell [nTPM]":"173.9","Blood RNA - naive CD4 T-cell [nTPM]":"318.9","Blood RNA - naive CD8 T-cell [nTPM]":"381.4","Blood RNA - neutrophil [nTPM]":"2578.1","Blood RNA - NK-cell [nTPM]":"274.5","Blood RNA - non-classical monocyte [nTPM]":"81.9","Blood RNA - plasmacytoid DC [nTPM]":"220.1","Blood RNA - T-reg [nTPM]":"350.3","Blood RNA - total PBMC [nTPM]":"584.9","Brain RNA - amygdala [nTPM]":"53.5","Brain RNA - basal ganglia [nTPM]":"81.9","Brain RNA - cerebellum [nTPM]":"79.6","Brain RNA - cerebral cortex [nTPM]":"70.0","Brain RNA - hippocampal formation [nTPM]":"52.2","Brain RNA - hypothalamus [nTPM]":"63.0","Brain RNA - medulla oblongata [nTPM]":"94.0","Brain RNA - midbrain [nTPM]":"79.4","Brain RNA - pons [nTPM]":"92.7","Brain RNA - spinal cord [nTPM]":"77.3","Brain RNA - thalamus [nTPM]":"77.6","Brain RNA - white matter [nTPM]":"109.4","Single Cell Type RNA - Adipocytes [nTPM]":"297.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"70.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"176.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"157.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"336.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"365.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"68.3","Single Cell Type RNA - Bipolar cells [nTPM]":"2.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"180.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"157.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"148.7","Single Cell Type RNA - Club cells [nTPM]":"222.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"163.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"56.4","Single Cell Type RNA - dendritic cells [nTPM]":"505.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"305.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"485.2","Single Cell Type RNA - Ductal cells [nTPM]":"245.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"112.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"151.9","Single Cell Type RNA - Endothelial cells [nTPM]":"76.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.5","Single Cell Type RNA - Erythroid cells [nTPM]":"18.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"72.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"471.9","Single Cell Type RNA - Fibroblasts [nTPM]":"156.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"108.1","Single Cell Type RNA - granulocytes [nTPM]":"214.9","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"94.2","Single Cell Type RNA - Hepatocytes [nTPM]":"52.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"227.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"153.1","Single Cell Type RNA - Ionocytes [nTPM]":"175.0","Single Cell Type RNA - Kupffer cells [nTPM]":"156.9","Single Cell Type RNA - Langerhans cells [nTPM]":"701.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.3","Single Cell Type RNA - Leydig cells [nTPM]":"56.2","Single Cell Type RNA - Macrophages [nTPM]":"422.0","Single Cell Type RNA - Melanocytes [nTPM]":"156.5","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"391.8","Single Cell Type RNA - Muller glia cells [nTPM]":"232.7","Single Cell Type RNA - NK-cells [nTPM]":"433.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"59.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"123.3","Single Cell Type RNA - Paneth cells [nTPM]":"236.1","Single Cell Type RNA - Peritubular cells [nTPM]":"68.4","Single Cell Type RNA - Plasma cells [nTPM]":"186.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"239.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"104.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"150.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.4","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"89.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"176.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"5.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"132.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.1","Single Cell Type RNA - T-cells [nTPM]":"278.7","Single Cell Type RNA - Theca cells [nTPM]":"16.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"88.9","Single Cell Type RNA - Urothelial cells [nTPM]":"368.6"},{"Gene":"LMNA","Gene synonym":["CMD1A","HGPS","LGMD1B","LMN1","LMNL1","MADA","PRO1"],"Ensembl":"ENSG00000160789","Gene description":"Lamin A\/C","Uniprot":["P02545"],"Chromosome":"1","Position":"156082573-156140081","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Cardiomyopathy","Charcot-Marie-Tooth disease","Congenital muscular dystrophy","Disease variant","Emery-Dreifuss muscular dystrophy","Limb-girdle muscular dystrophy","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"1533.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"85.1","T-reg":"83.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"85.1","granulocytes":"23.9","T-cells":"83.2"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004022","HPA006523","HPA006660"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5700000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"CAB004022":"AB_2136278","HPA006523":null,"HPA006660":"AB_1079231"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"280.2","Tissue RNA - adrenal gland [nTPM]":"174.8","Tissue RNA - amygdala [nTPM]":"17.6","Tissue RNA - appendix [nTPM]":"64.9","Tissue RNA - basal ganglia [nTPM]":"27.1","Tissue RNA - bone marrow [nTPM]":"58.1","Tissue RNA - breast [nTPM]":"231.5","Tissue RNA - cerebellum [nTPM]":"24.1","Tissue RNA - cerebral cortex [nTPM]":"20.6","Tissue RNA - cervix [nTPM]":"221.7","Tissue RNA - choroid plexus [nTPM]":"33.0","Tissue RNA - colon [nTPM]":"183.3","Tissue RNA - duodenum [nTPM]":"72.8","Tissue RNA - endometrium 1 [nTPM]":"271.4","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"256.2","Tissue RNA - fallopian tube [nTPM]":"173.8","Tissue RNA - gallbladder [nTPM]":"92.1","Tissue RNA - heart muscle [nTPM]":"221.7","Tissue RNA - hippocampal formation [nTPM]":"15.8","Tissue RNA - hypothalamus [nTPM]":"23.1","Tissue RNA - kidney [nTPM]":"120.9","Tissue RNA - liver [nTPM]":"93.2","Tissue RNA - lung [nTPM]":"188.5","Tissue RNA - lymph node [nTPM]":"18.2","Tissue RNA - medulla oblongata [nTPM]":"30.3","Tissue RNA - midbrain [nTPM]":"25.2","Tissue RNA - ovary [nTPM]":"178.2","Tissue RNA - pancreas [nTPM]":"81.8","Tissue RNA - parathyroid gland [nTPM]":"21.3","Tissue RNA - pituitary gland [nTPM]":"76.9","Tissue RNA - placenta [nTPM]":"53.0","Tissue RNA - pons [nTPM]":"26.1","Tissue RNA - prostate [nTPM]":"125.3","Tissue RNA - rectum [nTPM]":"38.2","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"176.1","Tissue RNA - seminal vesicle [nTPM]":"42.8","Tissue RNA - skeletal muscle [nTPM]":"190.0","Tissue RNA - skin 1 [nTPM]":"364.3","Tissue RNA - small intestine [nTPM]":"136.8","Tissue RNA - smooth muscle [nTPM]":"78.8","Tissue RNA - spinal cord [nTPM]":"21.0","Tissue RNA - spleen [nTPM]":"84.1","Tissue RNA - stomach 1 [nTPM]":"160.6","Tissue RNA - testis [nTPM]":"61.9","Tissue RNA - thalamus [nTPM]":"30.9","Tissue RNA - thymus [nTPM]":"15.3","Tissue RNA - thyroid gland [nTPM]":"147.4","Tissue RNA - tongue [nTPM]":"23.8","Tissue RNA - tonsil [nTPM]":"22.9","Tissue RNA - urinary bladder [nTPM]":"168.7","Tissue RNA - vagina [nTPM]":"217.6","Tissue RNA - white matter [nTPM]":"41.8","Cell RNA - A-431 [nTPM]":"518.8","Cell RNA - A549 [nTPM]":"269.7","Cell RNA - AF22 [nTPM]":"26.2","Cell RNA - AN3-CA [nTPM]":"72.4","Cell RNA - ASC diff [nTPM]":"119.5","Cell RNA - ASC TERT1 [nTPM]":"238.7","Cell RNA - BEWO [nTPM]":"169.4","Cell RNA - BJ [nTPM]":"607.3","Cell RNA - BJ hTERT+ [nTPM]":"379.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"221.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"146.8","Cell RNA - CACO-2 [nTPM]":"68.3","Cell RNA - CAPAN-2 [nTPM]":"311.9","Cell RNA - Daudi [nTPM]":"2.8","Cell RNA - EFO-21 [nTPM]":"338.7","Cell RNA - fHDF\/TERT166 [nTPM]":"417.9","Cell RNA - GAMG [nTPM]":"94.6","Cell RNA - HaCaT [nTPM]":"515.4","Cell RNA - HAP1 [nTPM]":"31.4","Cell RNA - HBEC3-KT [nTPM]":"227.8","Cell RNA - HBF TERT88 [nTPM]":"70.3","Cell RNA - HDLM-2 [nTPM]":"188.6","Cell RNA - HEK 293 [nTPM]":"50.8","Cell RNA - HEL [nTPM]":"175.4","Cell RNA - HeLa [nTPM]":"168.4","Cell RNA - Hep G2 [nTPM]":"130.8","Cell RNA - HHSteC [nTPM]":"124.0","Cell RNA - HL-60 [nTPM]":"25.7","Cell RNA - HMC-1 [nTPM]":"412.9","Cell RNA - HSkMC [nTPM]":"133.0","Cell RNA - hTCEpi [nTPM]":"92.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"154.8","Cell RNA - hTERT-HME1 [nTPM]":"134.7","Cell RNA - hTERT-RPE1 [nTPM]":"120.2","Cell RNA - HUVEC TERT2 [nTPM]":"207.5","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"82.8","Cell RNA - Karpas-707 [nTPM]":"21.9","Cell RNA - LHCN-M2 [nTPM]":"205.8","Cell RNA - MCF7 [nTPM]":"193.1","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"67.8","Cell RNA - NTERA-2 [nTPM]":"32.1","Cell RNA - OE19 [nTPM]":"202.9","Cell RNA - PC-3 [nTPM]":"706.0","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"195.9","Cell RNA - RPMI-8226 [nTPM]":"137.7","Cell RNA - RPTEC TERT1 [nTPM]":"128.9","Cell RNA - RT4 [nTPM]":"105.6","Cell RNA - SCLC-21H [nTPM]":"33.8","Cell RNA - SH-SY5Y [nTPM]":"114.9","Cell RNA - SiHa [nTPM]":"414.3","Cell RNA - SK-BR-3 [nTPM]":"154.2","Cell RNA - SK-MEL-30 [nTPM]":"427.4","Cell RNA - SuSa [nTPM]":"56.2","Cell RNA - T-47d [nTPM]":"230.1","Cell RNA - THP-1 [nTPM]":"74.2","Cell RNA - TIME [nTPM]":"727.9","Cell RNA - U-138 MG [nTPM]":"241.6","Cell RNA - U-2 OS [nTPM]":"233.0","Cell RNA - U-2197 [nTPM]":"389.1","Cell RNA - U-251 MG [nTPM]":"393.3","Cell RNA - U-266\/70 [nTPM]":"39.5","Cell RNA - U-266\/84 [nTPM]":"10.5","Cell RNA - U-698 [nTPM]":"4.9","Cell RNA - U-87 MG [nTPM]":"449.2","Cell RNA - U-937 [nTPM]":"24.8","Cell RNA - WM-115 [nTPM]":"760.4","Blood RNA - basophil [nTPM]":"23.9","Blood RNA - classical monocyte [nTPM]":"8.3","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"2.8","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"17.8","Blood RNA - memory CD8 T-cell [nTPM]":"7.3","Blood RNA - myeloid DC [nTPM]":"85.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"3.7","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"83.2","Blood RNA - total PBMC [nTPM]":"14.6","Brain RNA - amygdala [nTPM]":"17.6","Brain RNA - basal ganglia [nTPM]":"27.1","Brain RNA - cerebellum [nTPM]":"24.1","Brain RNA - cerebral cortex [nTPM]":"20.6","Brain RNA - hippocampal formation [nTPM]":"15.8","Brain RNA - hypothalamus [nTPM]":"23.1","Brain RNA - medulla oblongata [nTPM]":"30.3","Brain RNA - midbrain [nTPM]":"25.2","Brain RNA - pons [nTPM]":"26.1","Brain RNA - spinal cord [nTPM]":"21.0","Brain RNA - thalamus [nTPM]":"30.9","Brain RNA - white matter [nTPM]":"41.8","Single Cell Type RNA - Adipocytes [nTPM]":"353.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"262.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"350.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"179.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"610.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1235.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"446.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"531.6","Single Cell Type RNA - Bipolar cells [nTPM]":"7.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"542.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"374.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"94.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"191.6","Single Cell Type RNA - Club cells [nTPM]":"320.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"161.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"478.8","Single Cell Type RNA - dendritic cells [nTPM]":"239.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"614.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"109.5","Single Cell Type RNA - Ductal cells [nTPM]":"429.3","Single Cell Type RNA - Early spermatids [nTPM]":"38.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"215.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"209.4","Single Cell Type RNA - Endothelial cells [nTPM]":"386.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"431.5","Single Cell Type RNA - Erythroid cells [nTPM]":"70.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"360.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"387.8","Single Cell Type RNA - Fibroblasts [nTPM]":"622.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"505.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"270.5","Single Cell Type RNA - granulocytes [nTPM]":"1181.8","Single Cell Type RNA - Granulosa cells [nTPM]":"145.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"277.7","Single Cell Type RNA - Hepatocytes [nTPM]":"103.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"343.0","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"601.2","Single Cell Type RNA - Ionocytes [nTPM]":"177.0","Single Cell Type RNA - Kupffer cells [nTPM]":"60.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1533.4","Single Cell Type RNA - Late spermatids [nTPM]":"45.4","Single Cell Type RNA - Leydig cells [nTPM]":"288.6","Single Cell Type RNA - Macrophages [nTPM]":"409.0","Single Cell Type RNA - Melanocytes [nTPM]":"859.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"20.4","Single Cell Type RNA - Muller glia cells [nTPM]":"37.2","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"513.0","Single Cell Type RNA - Paneth cells [nTPM]":"384.1","Single Cell Type RNA - Peritubular cells [nTPM]":"287.3","Single Cell Type RNA - Plasma cells [nTPM]":"331.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"340.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"262.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"125.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"170.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.8","Single Cell Type RNA - Sertoli cells [nTPM]":"203.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1028.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"766.8","Single Cell Type RNA - Spermatocytes [nTPM]":"107.4","Single Cell Type RNA - Spermatogonia [nTPM]":"42.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"404.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"602.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"680.9","Single Cell Type RNA - T-cells [nTPM]":"472.3","Single Cell Type RNA - Theca cells [nTPM]":"111.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"513.8","Single Cell Type RNA - Urothelial cells [nTPM]":"942.6"},{"Gene":"LMNB2","Gene synonym":["LMN2"],"Ensembl":"ENSG00000176619","Gene description":"Lamin B2","Uniprot":["Q03252"],"Chromosome":"19","Position":"2427638-2456959","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"220.2","Extravillous trophoblasts":"81.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022593","HPA047863","HPA062477"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB022593":null,"HPA047863":"AB_2680189","HPA062477":"AB_2684776"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.88e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.53e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.34e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"15.3","Tissue RNA - basal ganglia [nTPM]":"8.6","Tissue RNA - bone marrow [nTPM]":"17.3","Tissue RNA - breast [nTPM]":"7.7","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"9.8","Tissue RNA - cervix [nTPM]":"11.9","Tissue RNA - choroid plexus [nTPM]":"6.4","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"10.9","Tissue RNA - endometrium 1 [nTPM]":"11.9","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"32.1","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"10.6","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"10.1","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"6.0","Tissue RNA - lung [nTPM]":"11.2","Tissue RNA - lymph node [nTPM]":"12.8","Tissue RNA - medulla oblongata [nTPM]":"8.7","Tissue RNA - midbrain [nTPM]":"9.0","Tissue RNA - ovary [nTPM]":"13.4","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"3.6","Tissue RNA - pituitary gland [nTPM]":"12.3","Tissue RNA - placenta [nTPM]":"14.6","Tissue RNA - pons [nTPM]":"8.4","Tissue RNA - prostate [nTPM]":"9.8","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"3.5","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"4.9","Tissue RNA - skeletal muscle [nTPM]":"14.9","Tissue RNA - skin 1 [nTPM]":"10.6","Tissue RNA - small intestine [nTPM]":"12.2","Tissue RNA - smooth muscle [nTPM]":"5.5","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"12.3","Tissue RNA - stomach 1 [nTPM]":"10.4","Tissue RNA - testis [nTPM]":"10.9","Tissue RNA - thalamus [nTPM]":"10.5","Tissue RNA - thymus [nTPM]":"23.1","Tissue RNA - thyroid gland [nTPM]":"8.7","Tissue RNA - tongue [nTPM]":"5.2","Tissue RNA - tonsil [nTPM]":"10.5","Tissue RNA - urinary bladder [nTPM]":"10.0","Tissue RNA - vagina [nTPM]":"12.4","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"181.5","Cell RNA - A549 [nTPM]":"114.0","Cell RNA - AF22 [nTPM]":"80.8","Cell RNA - AN3-CA [nTPM]":"105.7","Cell RNA - ASC diff [nTPM]":"17.3","Cell RNA - ASC TERT1 [nTPM]":"27.2","Cell RNA - BEWO [nTPM]":"107.5","Cell RNA - BJ [nTPM]":"119.2","Cell RNA - BJ hTERT+ [nTPM]":"57.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"117.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"88.8","Cell RNA - CACO-2 [nTPM]":"152.0","Cell RNA - CAPAN-2 [nTPM]":"75.6","Cell RNA - Daudi [nTPM]":"83.5","Cell RNA - EFO-21 [nTPM]":"47.8","Cell RNA - fHDF\/TERT166 [nTPM]":"55.9","Cell RNA - GAMG [nTPM]":"68.1","Cell RNA - HaCaT [nTPM]":"185.6","Cell RNA - HAP1 [nTPM]":"72.4","Cell RNA - HBEC3-KT [nTPM]":"84.8","Cell RNA - HBF TERT88 [nTPM]":"60.0","Cell RNA - HDLM-2 [nTPM]":"102.4","Cell RNA - HEK 293 [nTPM]":"86.3","Cell RNA - HEL [nTPM]":"66.4","Cell RNA - HeLa [nTPM]":"40.3","Cell RNA - Hep G2 [nTPM]":"119.8","Cell RNA - HHSteC [nTPM]":"20.9","Cell RNA - HL-60 [nTPM]":"93.5","Cell RNA - HMC-1 [nTPM]":"64.6","Cell RNA - HSkMC [nTPM]":"24.5","Cell RNA - hTCEpi [nTPM]":"21.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.4","Cell RNA - hTERT-HME1 [nTPM]":"49.7","Cell RNA - hTERT-RPE1 [nTPM]":"22.0","Cell RNA - HUVEC TERT2 [nTPM]":"60.9","Cell RNA - JURKAT [nTPM]":"76.2","Cell RNA - K-562 [nTPM]":"117.8","Cell RNA - Karpas-707 [nTPM]":"51.9","Cell RNA - LHCN-M2 [nTPM]":"56.4","Cell RNA - MCF7 [nTPM]":"105.4","Cell RNA - MOLT-4 [nTPM]":"107.9","Cell RNA - NB-4 [nTPM]":"51.8","Cell RNA - NTERA-2 [nTPM]":"154.0","Cell RNA - OE19 [nTPM]":"97.8","Cell RNA - PC-3 [nTPM]":"98.6","Cell RNA - REH [nTPM]":"150.1","Cell RNA - RH-30 [nTPM]":"102.4","Cell RNA - RPMI-8226 [nTPM]":"70.0","Cell RNA - RPTEC TERT1 [nTPM]":"33.7","Cell RNA - RT4 [nTPM]":"89.8","Cell RNA - SCLC-21H [nTPM]":"118.7","Cell RNA - SH-SY5Y [nTPM]":"68.8","Cell RNA - SiHa [nTPM]":"99.6","Cell RNA - SK-BR-3 [nTPM]":"65.6","Cell RNA - SK-MEL-30 [nTPM]":"39.6","Cell RNA - SuSa [nTPM]":"44.7","Cell RNA - T-47d [nTPM]":"65.9","Cell RNA - THP-1 [nTPM]":"95.7","Cell RNA - TIME [nTPM]":"85.1","Cell RNA - U-138 MG [nTPM]":"112.5","Cell RNA - U-2 OS [nTPM]":"116.6","Cell RNA - U-2197 [nTPM]":"174.8","Cell RNA - U-251 MG [nTPM]":"180.6","Cell RNA - U-266\/70 [nTPM]":"45.6","Cell RNA - U-266\/84 [nTPM]":"41.8","Cell RNA - U-698 [nTPM]":"83.5","Cell RNA - U-87 MG [nTPM]":"91.3","Cell RNA - U-937 [nTPM]":"88.5","Cell RNA - WM-115 [nTPM]":"148.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"8.6","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"9.8","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"10.1","Brain RNA - medulla oblongata [nTPM]":"8.7","Brain RNA - midbrain [nTPM]":"9.0","Brain RNA - pons [nTPM]":"8.4","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"10.5","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"8.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.2","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"9.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"8.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"5.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.4","Single Cell Type RNA - dendritic cells [nTPM]":"9.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"7.0","Single Cell Type RNA - Early spermatids [nTPM]":"220.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.9","Single Cell Type RNA - Endothelial cells [nTPM]":"12.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"81.6","Single Cell Type RNA - Fibroblasts [nTPM]":"14.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.7","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"31.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.2","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.8","Single Cell Type RNA - Langerhans cells [nTPM]":"18.2","Single Cell Type RNA - Late spermatids [nTPM]":"31.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"10.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"12.2","Single Cell Type RNA - Muller glia cells [nTPM]":"9.4","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.7","Single Cell Type RNA - Paneth cells [nTPM]":"9.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"25.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.2","Single Cell Type RNA - Spermatocytes [nTPM]":"8.6","Single Cell Type RNA - Spermatogonia [nTPM]":"15.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"12.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.1","Single Cell Type RNA - Urothelial cells [nTPM]":"19.2"},{"Gene":"LMX1A","Gene synonym":["LMX1","LMX1.1"],"Ensembl":"ENSG00000162761","Gene description":"LIM homeobox transcription factor 1 alpha","Uniprot":["Q8TE12"],"Chromosome":"1","Position":"165201867-165356715","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"choroid plexus":"20.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Early spermatids":"30.6","Enteroendocrine cells":"41.9","Late spermatids":"23.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028051","HPA030088"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 17: Intestinal endocrine cells - Hormone signaling","Subcellular main location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA028051":"AB_10599731","HPA030088":"AB_10601106"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"20.4","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"30.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"23.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"LOXHD1","Gene synonym":["DFNB77","FLJ32670","LH2D1"],"Ensembl":"ENSG00000167210","Gene description":"Lipoxygenase homology domains 1","Uniprot":["Q8IVV2"],"Chromosome":"18","Position":"46476972-46657220","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"7.2","kidney":"6.9","testis":"23.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"70","RNA single cell type specific nTPM":{"Early spermatids":"199.3","Late spermatids":"439.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.5"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"3.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077128"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA077128":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.3","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"2.8","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"23.0","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"199.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"439.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"4.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"LRAT","Gene synonym":["LCA14"],"Ensembl":"ENSG00000121207","Gene description":"Lecithin retinol acyltransferase","Uniprot":["O95237"],"Chromosome":"4","Position":"154626945-154753120","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Granulosa cells":"104.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"NTERA-2":"15.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070726"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA070726":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"15.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"1.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"15.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"104.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"LRIT3","Gene synonym":["CSNB1F","FIGLER4","FLJ44691"],"Ensembl":"ENSG00000183423","Gene description":"Leucine rich repeat, Ig-like and transmembrane domains 3","Uniprot":["Q3SXY7"],"Chromosome":"4","Position":"109848107-109872315","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"retina":"17.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"33.3","Muller glia cells":"10.2","Rod photoreceptor cells":"9.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013454"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA013454":"AB_1853277"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"17.6","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"10.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"LRP4","Gene synonym":["CLSS","LRP-4","MEGF7","SOST2"],"Ensembl":"ENSG00000134569","Gene description":"LDL receptor related protein 4","Uniprot":["O75096"],"Chromosome":"11","Position":"46856717-46918642","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Endocytosis","Wnt signaling pathway"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"46.7","skin 1":"31.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"123.1","Cone photoreceptor cells":"41.7","Distal enterocytes":"31.1","Oligodendrocyte precursor cells":"137.2","Oligodendrocytes":"31.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"12.2","endometrial cancer":"8.6","glioma":"13.2","testis cancer":"15.6","thyroid cancer":"28.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"21.3","SuSa":"16.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011934","HPA012300"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nucleoplasm","Nucleoli","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA011934":"AB_1853286","HPA012300":"AB_1853288"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"23.3","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"30.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"19.1","Tissue RNA - cerebral cortex [nTPM]":"21.3","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"4.8","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"1.8","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"6.9","Tissue RNA - hippocampal formation [nTPM]":"24.2","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"46.7","Tissue RNA - midbrain [nTPM]":"23.0","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"19.8","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"7.9","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"31.6","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"21.3","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"30.9","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"25.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"9.6","Cell RNA - AF22 [nTPM]":"21.3","Cell RNA - AN3-CA [nTPM]":"6.5","Cell RNA - ASC diff [nTPM]":"13.4","Cell RNA - ASC TERT1 [nTPM]":"3.7","Cell RNA - BEWO [nTPM]":"4.9","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.2","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"11.4","Cell RNA - GAMG [nTPM]":"3.1","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"12.0","Cell RNA - HBEC3-KT [nTPM]":"7.5","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"10.3","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"6.8","Cell RNA - HHSteC [nTPM]":"2.8","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"4.5","Cell RNA - hTCEpi [nTPM]":"4.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.4","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"2.5","Cell RNA - HUVEC TERT2 [nTPM]":"2.5","Cell RNA - JURKAT [nTPM]":"2.6","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.6","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"11.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"7.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"2.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"14.2","Cell RNA - SiHa [nTPM]":"1.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.4","Cell RNA - SuSa [nTPM]":"16.2","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"5.7","Cell RNA - U-2 OS [nTPM]":"3.5","Cell RNA - U-2197 [nTPM]":"6.5","Cell RNA - U-251 MG [nTPM]":"2.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"4.3","Cell RNA - U-937 [nTPM]":"0.7","Cell RNA - WM-115 [nTPM]":"2.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"23.3","Brain RNA - basal ganglia [nTPM]":"30.5","Brain RNA - cerebellum [nTPM]":"19.1","Brain RNA - cerebral cortex [nTPM]":"21.3","Brain RNA - hippocampal formation [nTPM]":"24.2","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"46.7","Brain RNA - midbrain [nTPM]":"23.0","Brain RNA - pons [nTPM]":"19.8","Brain RNA - spinal cord [nTPM]":"21.3","Brain RNA - thalamus [nTPM]":"30.9","Brain RNA - white matter [nTPM]":"25.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.9","Single Cell Type RNA - Astrocytes [nTPM]":"123.1","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.4","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"1.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"137.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"8.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"LRP5","Gene synonym":["BMND1","EVR1","EVR4","HBM","LR3","LRP7","OPPG","OPS","OPTA1","VBCH2"],"Ensembl":"ENSG00000162337","Gene description":"LDL receptor related protein 5","Uniprot":["O75197"],"Chromosome":"11","Position":"68312591-68449275","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis","Wnt signaling pathway"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Disease variant","Osteogenesis imperfecta","Osteopetrosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"129.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"84.7","Proximal enterocytes":"54.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"161.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013001","HPA030505"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013001":"AB_2533267","HPA030505":"AB_2673505"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.55e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"35.6","Tissue RNA - adrenal gland [nTPM]":"37.6","Tissue RNA - amygdala [nTPM]":"9.6","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"11.4","Tissue RNA - bone marrow [nTPM]":"3.2","Tissue RNA - breast [nTPM]":"36.9","Tissue RNA - cerebellum [nTPM]":"10.9","Tissue RNA - cerebral cortex [nTPM]":"11.2","Tissue RNA - cervix [nTPM]":"26.0","Tissue RNA - choroid plexus [nTPM]":"44.4","Tissue RNA - colon [nTPM]":"32.4","Tissue RNA - duodenum [nTPM]":"43.1","Tissue RNA - endometrium 1 [nTPM]":"30.6","Tissue RNA - epididymis [nTPM]":"4.1","Tissue RNA - esophagus [nTPM]":"18.5","Tissue RNA - fallopian tube [nTPM]":"26.4","Tissue RNA - gallbladder [nTPM]":"21.0","Tissue RNA - heart muscle [nTPM]":"35.7","Tissue RNA - hippocampal formation [nTPM]":"8.6","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"30.3","Tissue RNA - liver [nTPM]":"129.7","Tissue RNA - lung [nTPM]":"23.3","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"27.9","Tissue RNA - pancreas [nTPM]":"34.9","Tissue RNA - parathyroid gland [nTPM]":"11.6","Tissue RNA - pituitary gland [nTPM]":"15.9","Tissue RNA - placenta [nTPM]":"23.2","Tissue RNA - pons [nTPM]":"11.7","Tissue RNA - prostate [nTPM]":"25.1","Tissue RNA - rectum [nTPM]":"11.2","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"73.3","Tissue RNA - seminal vesicle [nTPM]":"20.0","Tissue RNA - skeletal muscle [nTPM]":"10.4","Tissue RNA - skin 1 [nTPM]":"19.3","Tissue RNA - small intestine [nTPM]":"44.8","Tissue RNA - smooth muscle [nTPM]":"11.1","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"8.9","Tissue RNA - stomach 1 [nTPM]":"31.8","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"10.2","Tissue RNA - thymus [nTPM]":"9.6","Tissue RNA - thyroid gland [nTPM]":"33.4","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"24.5","Tissue RNA - vagina [nTPM]":"19.4","Tissue RNA - white matter [nTPM]":"10.6","Cell RNA - A-431 [nTPM]":"30.9","Cell RNA - A549 [nTPM]":"103.6","Cell RNA - AF22 [nTPM]":"11.0","Cell RNA - AN3-CA [nTPM]":"25.4","Cell RNA - ASC diff [nTPM]":"20.6","Cell RNA - ASC TERT1 [nTPM]":"11.4","Cell RNA - BEWO [nTPM]":"47.0","Cell RNA - BJ [nTPM]":"14.0","Cell RNA - BJ hTERT+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.5","Cell RNA - CACO-2 [nTPM]":"58.7","Cell RNA - CAPAN-2 [nTPM]":"104.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"87.5","Cell RNA - fHDF\/TERT166 [nTPM]":"18.2","Cell RNA - GAMG [nTPM]":"35.1","Cell RNA - HaCaT [nTPM]":"38.9","Cell RNA - HAP1 [nTPM]":"9.9","Cell RNA - HBEC3-KT [nTPM]":"37.3","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"5.0","Cell RNA - HEK 293 [nTPM]":"22.6","Cell RNA - HEL [nTPM]":"21.6","Cell RNA - HeLa [nTPM]":"52.8","Cell RNA - Hep G2 [nTPM]":"77.2","Cell RNA - HHSteC [nTPM]":"20.8","Cell RNA - HL-60 [nTPM]":"15.8","Cell RNA - HMC-1 [nTPM]":"2.0","Cell RNA - HSkMC [nTPM]":"16.4","Cell RNA - hTCEpi [nTPM]":"12.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"22.3","Cell RNA - HUVEC TERT2 [nTPM]":"23.7","Cell RNA - JURKAT [nTPM]":"18.8","Cell RNA - K-562 [nTPM]":"38.5","Cell RNA - Karpas-707 [nTPM]":"1.6","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"69.5","Cell RNA - MOLT-4 [nTPM]":"23.7","Cell RNA - NB-4 [nTPM]":"62.7","Cell RNA - NTERA-2 [nTPM]":"19.6","Cell RNA - OE19 [nTPM]":"161.2","Cell RNA - PC-3 [nTPM]":"41.7","Cell RNA - REH [nTPM]":"29.6","Cell RNA - RH-30 [nTPM]":"30.1","Cell RNA - RPMI-8226 [nTPM]":"49.7","Cell RNA - RPTEC TERT1 [nTPM]":"14.2","Cell RNA - RT4 [nTPM]":"82.1","Cell RNA - SCLC-21H [nTPM]":"10.6","Cell RNA - SH-SY5Y [nTPM]":"21.6","Cell RNA - SiHa [nTPM]":"37.0","Cell RNA - SK-BR-3 [nTPM]":"49.4","Cell RNA - SK-MEL-30 [nTPM]":"41.0","Cell RNA - SuSa [nTPM]":"5.3","Cell RNA - T-47d [nTPM]":"34.6","Cell RNA - THP-1 [nTPM]":"36.2","Cell RNA - TIME [nTPM]":"31.5","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"9.0","Cell RNA - U-2197 [nTPM]":"11.6","Cell RNA - U-251 MG [nTPM]":"15.8","Cell RNA - U-266\/70 [nTPM]":"6.3","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"6.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"11.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.6","Brain RNA - basal ganglia [nTPM]":"11.4","Brain RNA - cerebellum [nTPM]":"10.9","Brain RNA - cerebral cortex [nTPM]":"11.2","Brain RNA - hippocampal formation [nTPM]":"8.6","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"11.7","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"10.2","Brain RNA - white matter [nTPM]":"10.6","Single Cell Type RNA - Adipocytes [nTPM]":"37.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.4","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"49.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.5","Single Cell Type RNA - Endothelial cells [nTPM]":"20.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.5","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"84.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.8","Single Cell Type RNA - Hepatocytes [nTPM]":"52.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.5","Single Cell Type RNA - Paneth cells [nTPM]":"32.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"5.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"54.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"7.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.8","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.1","Single Cell Type RNA - Urothelial cells [nTPM]":"13.8"},{"Gene":"LRPAP1","Gene synonym":["A2MRAP","HBP44","RAP"],"Ensembl":"ENSG00000163956","Gene description":"LDL receptor related protein associated protein 1","Uniprot":["P30533"],"Chromosome":"4","Position":"3503612-3532446","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Heparin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"584.3","Syncytiotrophoblasts":"693.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008001","CAB025518"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"810000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB025518":null,"HPA008001":"AB_1853292"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.67e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"9.0","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"8.6","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"8.9","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"7.6","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"5.8","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"19.3","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"8.1","Tissue RNA - kidney [nTPM]":"12.7","Tissue RNA - liver [nTPM]":"9.6","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"6.9","Tissue RNA - ovary [nTPM]":"9.5","Tissue RNA - pancreas [nTPM]":"14.4","Tissue RNA - parathyroid gland [nTPM]":"7.7","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"7.9","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"10.1","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"8.9","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"6.7","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"8.6","Tissue RNA - stomach 1 [nTPM]":"9.2","Tissue RNA - testis [nTPM]":"9.2","Tissue RNA - thalamus [nTPM]":"7.5","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"8.9","Tissue RNA - tongue [nTPM]":"2.4","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"3.7","Cell RNA - A549 [nTPM]":"7.4","Cell RNA - AF22 [nTPM]":"5.7","Cell RNA - AN3-CA [nTPM]":"8.2","Cell RNA - ASC diff [nTPM]":"5.5","Cell RNA - ASC TERT1 [nTPM]":"2.9","Cell RNA - BEWO [nTPM]":"12.5","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"14.9","Cell RNA - CAPAN-2 [nTPM]":"7.0","Cell RNA - Daudi [nTPM]":"2.1","Cell RNA - EFO-21 [nTPM]":"6.0","Cell RNA - fHDF\/TERT166 [nTPM]":"4.2","Cell RNA - GAMG [nTPM]":"7.0","Cell RNA - HaCaT [nTPM]":"6.2","Cell RNA - HAP1 [nTPM]":"3.4","Cell RNA - HBEC3-KT [nTPM]":"5.8","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"7.9","Cell RNA - HEL [nTPM]":"2.9","Cell RNA - HeLa [nTPM]":"7.8","Cell RNA - Hep G2 [nTPM]":"10.4","Cell RNA - HHSteC [nTPM]":"4.2","Cell RNA - HL-60 [nTPM]":"4.7","Cell RNA - HMC-1 [nTPM]":"12.5","Cell RNA - HSkMC [nTPM]":"4.0","Cell RNA - hTCEpi [nTPM]":"4.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.9","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.7","Cell RNA - HUVEC TERT2 [nTPM]":"5.2","Cell RNA - JURKAT [nTPM]":"3.9","Cell RNA - K-562 [nTPM]":"5.1","Cell RNA - Karpas-707 [nTPM]":"7.0","Cell RNA - LHCN-M2 [nTPM]":"3.6","Cell RNA - MCF7 [nTPM]":"5.9","Cell RNA - MOLT-4 [nTPM]":"3.1","Cell RNA - NB-4 [nTPM]":"18.4","Cell RNA - NTERA-2 [nTPM]":"4.9","Cell RNA - OE19 [nTPM]":"5.1","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"4.3","Cell RNA - RH-30 [nTPM]":"4.2","Cell RNA - RPMI-8226 [nTPM]":"7.1","Cell RNA - RPTEC TERT1 [nTPM]":"4.8","Cell RNA - RT4 [nTPM]":"8.6","Cell RNA - SCLC-21H [nTPM]":"5.6","Cell RNA - SH-SY5Y [nTPM]":"4.6","Cell RNA - SiHa [nTPM]":"7.4","Cell RNA - SK-BR-3 [nTPM]":"3.0","Cell RNA - SK-MEL-30 [nTPM]":"8.1","Cell RNA - SuSa [nTPM]":"3.4","Cell RNA - T-47d [nTPM]":"6.7","Cell RNA - THP-1 [nTPM]":"8.6","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"5.1","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"4.1","Cell RNA - U-251 MG [nTPM]":"8.2","Cell RNA - U-266\/70 [nTPM]":"4.2","Cell RNA - U-266\/84 [nTPM]":"2.9","Cell RNA - U-698 [nTPM]":"2.8","Cell RNA - U-87 MG [nTPM]":"5.9","Cell RNA - U-937 [nTPM]":"13.3","Cell RNA - WM-115 [nTPM]":"7.2","Blood RNA - basophil [nTPM]":"21.9","Blood RNA - classical monocyte [nTPM]":"23.2","Blood RNA - eosinophil [nTPM]":"60.1","Blood RNA - gdT-cell [nTPM]":"9.3","Blood RNA - intermediate monocyte [nTPM]":"19.7","Blood RNA - MAIT T-cell [nTPM]":"8.1","Blood RNA - memory B-cell [nTPM]":"9.9","Blood RNA - memory CD4 T-cell [nTPM]":"8.6","Blood RNA - memory CD8 T-cell [nTPM]":"8.8","Blood RNA - myeloid DC [nTPM]":"13.3","Blood RNA - naive B-cell [nTPM]":"10.0","Blood RNA - naive CD4 T-cell [nTPM]":"9.4","Blood RNA - naive CD8 T-cell [nTPM]":"8.6","Blood RNA - neutrophil [nTPM]":"20.5","Blood RNA - NK-cell [nTPM]":"11.7","Blood RNA - non-classical monocyte [nTPM]":"19.1","Blood RNA - plasmacytoid DC [nTPM]":"10.2","Blood RNA - T-reg [nTPM]":"11.5","Blood RNA - total PBMC [nTPM]":"27.3","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"8.6","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"8.1","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"6.9","Brain RNA - pons [nTPM]":"7.9","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"7.5","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"95.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"109.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"90.9","Single Cell Type RNA - Astrocytes [nTPM]":"21.2","Single Cell Type RNA - B-cells [nTPM]":"78.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"67.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"174.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"267.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.9","Single Cell Type RNA - Bipolar cells [nTPM]":"70.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"75.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"84.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"165.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"108.7","Single Cell Type RNA - Club cells [nTPM]":"158.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"195.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"584.3","Single Cell Type RNA - dendritic cells [nTPM]":"75.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"147.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"159.3","Single Cell Type RNA - Early spermatids [nTPM]":"40.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"85.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"229.6","Single Cell Type RNA - Endothelial cells [nTPM]":"88.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"82.6","Single Cell Type RNA - Erythroid cells [nTPM]":"35.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"107.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"184.0","Single Cell Type RNA - Fibroblasts [nTPM]":"152.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"79.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"71.2","Single Cell Type RNA - granulocytes [nTPM]":"81.1","Single Cell Type RNA - Granulosa cells [nTPM]":"102.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"62.4","Single Cell Type RNA - Hepatocytes [nTPM]":"92.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"243.1","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"121.6","Single Cell Type RNA - Ionocytes [nTPM]":"164.8","Single Cell Type RNA - Kupffer cells [nTPM]":"100.5","Single Cell Type RNA - Langerhans cells [nTPM]":"80.2","Single Cell Type RNA - Late spermatids [nTPM]":"60.0","Single Cell Type RNA - Leydig cells [nTPM]":"126.2","Single Cell Type RNA - Macrophages [nTPM]":"154.2","Single Cell Type RNA - Melanocytes [nTPM]":"147.7","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"107.1","Single Cell Type RNA - Muller glia cells [nTPM]":"140.0","Single Cell Type RNA - NK-cells [nTPM]":"91.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"95.4","Single Cell Type RNA - Paneth cells [nTPM]":"153.4","Single Cell Type RNA - Peritubular cells [nTPM]":"151.6","Single Cell Type RNA - Plasma cells [nTPM]":"205.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"124.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"204.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"273.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"144.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"86.2","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"82.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"108.1","Single Cell Type RNA - Spermatocytes [nTPM]":"272.5","Single Cell Type RNA - Spermatogonia [nTPM]":"161.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"61.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"693.5","Single Cell Type RNA - T-cells [nTPM]":"86.0","Single Cell Type RNA - Theca cells [nTPM]":"99.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"109.9","Single Cell Type RNA - Urothelial cells [nTPM]":"140.5"},{"Gene":"LRRK2","Gene synonym":["DKFZp434H2111","FLJ45829","PARK8","RIPK7","ROCO2"],"Ensembl":"ENSG00000188906","Gene description":"Leucine rich repeat kinase 2","Uniprot":["Q5S007"],"Chromosome":"12","Position":"40196744-40369285","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Differentiation"],"Molecular function":["GTPase activation","Hydrolase","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lung":"52.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"502.2","Excitatory neurons":"92.0","monocytes":"133.1","Oligodendrocyte precursor cells":"256.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"17.1","thyroid cancer":"22.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"neutrophil":"58.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"58.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"4.6","ASC TERT1":"5.6","BJ hTERT+":"3.2","RPTEC TERT1":"7.8","T-47d":"3.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014293","CAB037160"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB037160":"AB_1840989","HPA014293":"AB_1853353"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.02e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"2.6","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"7.0","Tissue RNA - fallopian tube [nTPM]":"4.1","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"52.4","Tissue RNA - lymph node [nTPM]":"6.8","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"3.6","Tissue RNA - parathyroid gland [nTPM]":"8.4","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"2.6","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"10.8","Tissue RNA - stomach 1 [nTPM]":"2.1","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"2.5","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"7.9","Tissue RNA - tonsil [nTPM]":"5.4","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"5.5","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"4.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.3","Cell RNA - ASC TERT1 [nTPM]":"5.6","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.3","Cell RNA - BJ hTERT+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"7.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"2.7","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"3.1","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"7.2","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"5.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"58.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"6.9","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"502.2","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"29.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"8.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"17.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"92.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"16.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"13.9","Single Cell Type RNA - Granulosa cells [nTPM]":"2.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.6","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"55.8","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"52.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"73.1","Single Cell Type RNA - monocytes [nTPM]":"133.1","Single Cell Type RNA - Muller glia cells [nTPM]":"8.6","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"256.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"3.4","Single Cell Type RNA - Theca cells [nTPM]":"11.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"LRSAM1","Gene synonym":["CMT2P","FLJ31641","RIFLE","TAL"],"Ensembl":"ENSG00000148356","Gene description":"Leucine rich repeat and sterile alpha motif containing 1","Uniprot":["Q6UWE0"],"Chromosome":"9","Position":"127451489-127503499","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Protein transport","Transport","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"32.0","Excitatory neurons":"28.6","Inhibitory neurons":"26.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021403","HPA021844","CAB037304"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB037304":"AB_2138198","HPA021403":"AB_1853366","HPA021844":"AB_1853368"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.78e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.72e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.2","Tissue RNA - adrenal gland [nTPM]":"9.8","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"8.6","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"7.3","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"12.5","Tissue RNA - cervix [nTPM]":"10.7","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"16.5","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"5.9","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"17.3","Tissue RNA - hippocampal formation [nTPM]":"8.8","Tissue RNA - hypothalamus [nTPM]":"8.8","Tissue RNA - kidney [nTPM]":"9.0","Tissue RNA - liver [nTPM]":"8.8","Tissue RNA - lung [nTPM]":"7.4","Tissue RNA - lymph node [nTPM]":"4.5","Tissue RNA - medulla oblongata [nTPM]":"11.1","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"10.7","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"6.9","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"9.1","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"7.5","Tissue RNA - seminal vesicle [nTPM]":"5.6","Tissue RNA - skeletal muscle [nTPM]":"13.5","Tissue RNA - skin 1 [nTPM]":"21.2","Tissue RNA - small intestine [nTPM]":"9.1","Tissue RNA - smooth muscle [nTPM]":"5.0","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"9.5","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"12.3","Tissue RNA - vagina [nTPM]":"10.2","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"10.8","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"10.7","Cell RNA - ASC diff [nTPM]":"9.8","Cell RNA - ASC TERT1 [nTPM]":"9.1","Cell RNA - BEWO [nTPM]":"8.3","Cell RNA - BJ [nTPM]":"5.3","Cell RNA - BJ hTERT+ [nTPM]":"8.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.6","Cell RNA - CACO-2 [nTPM]":"8.9","Cell RNA - CAPAN-2 [nTPM]":"5.9","Cell RNA - Daudi [nTPM]":"9.8","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.9","Cell RNA - GAMG [nTPM]":"3.6","Cell RNA - HaCaT [nTPM]":"18.7","Cell RNA - HAP1 [nTPM]":"7.8","Cell RNA - HBEC3-KT [nTPM]":"13.3","Cell RNA - HBF TERT88 [nTPM]":"3.8","Cell RNA - HDLM-2 [nTPM]":"11.5","Cell RNA - HEK 293 [nTPM]":"5.3","Cell RNA - HEL [nTPM]":"5.2","Cell RNA - HeLa [nTPM]":"9.0","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"6.2","Cell RNA - HMC-1 [nTPM]":"7.3","Cell RNA - HSkMC [nTPM]":"6.1","Cell RNA - hTCEpi [nTPM]":"7.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.1","Cell RNA - hTERT-HME1 [nTPM]":"12.2","Cell RNA - hTERT-RPE1 [nTPM]":"10.7","Cell RNA - HUVEC TERT2 [nTPM]":"11.2","Cell RNA - JURKAT [nTPM]":"7.6","Cell RNA - K-562 [nTPM]":"4.8","Cell RNA - Karpas-707 [nTPM]":"7.6","Cell RNA - LHCN-M2 [nTPM]":"4.5","Cell RNA - MCF7 [nTPM]":"17.6","Cell RNA - MOLT-4 [nTPM]":"3.9","Cell RNA - NB-4 [nTPM]":"4.5","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"17.4","Cell RNA - PC-3 [nTPM]":"9.3","Cell RNA - REH [nTPM]":"7.1","Cell RNA - RH-30 [nTPM]":"5.6","Cell RNA - RPMI-8226 [nTPM]":"18.4","Cell RNA - RPTEC TERT1 [nTPM]":"11.5","Cell RNA - RT4 [nTPM]":"5.1","Cell RNA - SCLC-21H [nTPM]":"9.8","Cell RNA - SH-SY5Y [nTPM]":"9.2","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"8.8","Cell RNA - SuSa [nTPM]":"4.3","Cell RNA - T-47d [nTPM]":"26.5","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"10.2","Cell RNA - U-138 MG [nTPM]":"4.6","Cell RNA - U-2 OS [nTPM]":"5.6","Cell RNA - U-2197 [nTPM]":"4.2","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"7.9","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"9.1","Cell RNA - U-937 [nTPM]":"4.5","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"18.5","Blood RNA - classical monocyte [nTPM]":"4.8","Blood RNA - eosinophil [nTPM]":"21.3","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"6.5","Blood RNA - MAIT T-cell [nTPM]":"4.7","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"6.1","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"4.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"6.8","Blood RNA - plasmacytoid DC [nTPM]":"3.6","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"3.8","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"8.6","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"12.5","Brain RNA - hippocampal formation [nTPM]":"8.8","Brain RNA - hypothalamus [nTPM]":"8.8","Brain RNA - medulla oblongata [nTPM]":"11.1","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"32.0","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.0","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.7","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.6","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"7.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.3","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"7.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"7.4","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"5.7","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"3.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"LRTOMT","Gene synonym":["CFAP111","COMT2","DFNB63","LRRC51","LRTOMT1","LRTOMT2"],"Ensembl":"ENSG00000184154","Gene description":"Leucine rich transmembrane and O-methyltransferase domain containing","Uniprot":["Q96E66"],"Chromosome":"11","Position":"72080337-72096895","Protein class":["Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"67.1","testis":"49.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Early spermatids":"574.9","Late spermatids":"2222.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"T-47d":"39.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039949"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA039949":"AB_10960708"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.70e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.36e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"21.1","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"21.8","Tissue RNA - bone marrow [nTPM]":"2.1","Tissue RNA - breast [nTPM]":"8.7","Tissue RNA - cerebellum [nTPM]":"19.5","Tissue RNA - cerebral cortex [nTPM]":"24.2","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"25.1","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"7.2","Tissue RNA - epididymis [nTPM]":"17.1","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"67.1","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"19.1","Tissue RNA - hypothalamus [nTPM]":"19.2","Tissue RNA - kidney [nTPM]":"11.7","Tissue RNA - liver [nTPM]":"7.9","Tissue RNA - lung [nTPM]":"7.7","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"23.0","Tissue RNA - midbrain [nTPM]":"25.7","Tissue RNA - ovary [nTPM]":"8.1","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"10.3","Tissue RNA - pituitary gland [nTPM]":"8.9","Tissue RNA - placenta [nTPM]":"5.4","Tissue RNA - pons [nTPM]":"21.4","Tissue RNA - prostate [nTPM]":"9.3","Tissue RNA - rectum [nTPM]":"7.7","Tissue RNA - retina [nTPM]":"19.7","Tissue RNA - salivary gland [nTPM]":"4.4","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"7.5","Tissue RNA - skin 1 [nTPM]":"5.8","Tissue RNA - small intestine [nTPM]":"3.4","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"23.4","Tissue RNA - spleen [nTPM]":"4.0","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"49.3","Tissue RNA - thalamus [nTPM]":"21.0","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"11.0","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"3.6","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"22.0","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"13.7","Cell RNA - AF22 [nTPM]":"8.9","Cell RNA - AN3-CA [nTPM]":"6.9","Cell RNA - ASC diff [nTPM]":"7.3","Cell RNA - ASC TERT1 [nTPM]":"6.7","Cell RNA - BEWO [nTPM]":"2.1","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.5","Cell RNA - CACO-2 [nTPM]":"6.6","Cell RNA - CAPAN-2 [nTPM]":"20.4","Cell RNA - Daudi [nTPM]":"5.1","Cell RNA - EFO-21 [nTPM]":"6.6","Cell RNA - fHDF\/TERT166 [nTPM]":"7.8","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"7.3","Cell RNA - HAP1 [nTPM]":"6.3","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"9.4","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"3.5","Cell RNA - HeLa [nTPM]":"6.3","Cell RNA - Hep G2 [nTPM]":"4.8","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"3.0","Cell RNA - HMC-1 [nTPM]":"3.9","Cell RNA - HSkMC [nTPM]":"2.9","Cell RNA - hTCEpi [nTPM]":"5.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"4.6","Cell RNA - hTERT-RPE1 [nTPM]":"6.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.5","Cell RNA - JURKAT [nTPM]":"10.2","Cell RNA - K-562 [nTPM]":"4.0","Cell RNA - Karpas-707 [nTPM]":"7.8","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"13.6","Cell RNA - MOLT-4 [nTPM]":"9.0","Cell RNA - NB-4 [nTPM]":"6.0","Cell RNA - NTERA-2 [nTPM]":"4.4","Cell RNA - OE19 [nTPM]":"22.8","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"10.8","Cell RNA - RH-30 [nTPM]":"8.6","Cell RNA - RPMI-8226 [nTPM]":"7.7","Cell RNA - RPTEC TERT1 [nTPM]":"15.9","Cell RNA - RT4 [nTPM]":"4.7","Cell RNA - SCLC-21H [nTPM]":"8.2","Cell RNA - SH-SY5Y [nTPM]":"6.2","Cell RNA - SiHa [nTPM]":"8.7","Cell RNA - SK-BR-3 [nTPM]":"19.4","Cell RNA - SK-MEL-30 [nTPM]":"10.4","Cell RNA - SuSa [nTPM]":"6.1","Cell RNA - T-47d [nTPM]":"39.6","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"6.5","Cell RNA - U-138 MG [nTPM]":"4.0","Cell RNA - U-2 OS [nTPM]":"5.7","Cell RNA - U-2197 [nTPM]":"11.3","Cell RNA - U-251 MG [nTPM]":"3.1","Cell RNA - U-266\/70 [nTPM]":"8.0","Cell RNA - U-266\/84 [nTPM]":"9.4","Cell RNA - U-698 [nTPM]":"5.8","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"4.5","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"3.5","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"3.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"3.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"6.1","Blood RNA - NK-cell [nTPM]":"6.6","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"4.6","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"21.1","Brain RNA - basal ganglia [nTPM]":"21.8","Brain RNA - cerebellum [nTPM]":"19.5","Brain RNA - cerebral cortex [nTPM]":"24.2","Brain RNA - hippocampal formation [nTPM]":"19.1","Brain RNA - hypothalamus [nTPM]":"19.2","Brain RNA - medulla oblongata [nTPM]":"23.0","Brain RNA - midbrain [nTPM]":"25.7","Brain RNA - pons [nTPM]":"21.4","Brain RNA - spinal cord [nTPM]":"23.4","Brain RNA - thalamus [nTPM]":"21.0","Brain RNA - white matter [nTPM]":"22.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"10.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"7.5","Single Cell Type RNA - Early spermatids [nTPM]":"574.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"84.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"6.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"2222.2","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"1.4","Single Cell Type RNA - Muller glia cells [nTPM]":"21.3","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"5.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"113.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.9","Single Cell Type RNA - Spermatocytes [nTPM]":"90.3","Single Cell Type RNA - Spermatogonia [nTPM]":"28.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.1","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"LSS","Gene synonym":["OSC"],"Ensembl":"ENSG00000160285","Gene description":"Lanosterol synthase","Uniprot":["P48449"],"Chromosome":"21","Position":"46188141-46228824","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis"],"Molecular function":["Isomerase"],"Disease involvement":["Cataract","Disease variant","Hypotrichosis","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"132.0","Oligodendrocytes":"158.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"234.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032060","HPA032062","CAB034116"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034116":"AB_2138611","HPA032060":"AB_10671085","HPA032062":"AB_2674134"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.80e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.07e-4"},"Tissue RNA - adipose tissue [nTPM]":"29.3","Tissue RNA - adrenal gland [nTPM]":"38.9","Tissue RNA - amygdala [nTPM]":"20.0","Tissue RNA - appendix [nTPM]":"10.8","Tissue RNA - basal ganglia [nTPM]":"30.8","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"22.3","Tissue RNA - cerebellum [nTPM]":"38.9","Tissue RNA - cerebral cortex [nTPM]":"33.5","Tissue RNA - cervix [nTPM]":"20.8","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"22.9","Tissue RNA - duodenum [nTPM]":"28.5","Tissue RNA - endometrium 1 [nTPM]":"26.6","Tissue RNA - epididymis [nTPM]":"12.1","Tissue RNA - esophagus [nTPM]":"39.7","Tissue RNA - fallopian tube [nTPM]":"18.0","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"25.1","Tissue RNA - hippocampal formation [nTPM]":"15.7","Tissue RNA - hypothalamus [nTPM]":"26.2","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"54.8","Tissue RNA - lung [nTPM]":"24.1","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"62.3","Tissue RNA - midbrain [nTPM]":"40.7","Tissue RNA - ovary [nTPM]":"30.3","Tissue RNA - pancreas [nTPM]":"19.4","Tissue RNA - parathyroid gland [nTPM]":"12.2","Tissue RNA - pituitary gland [nTPM]":"25.9","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"65.7","Tissue RNA - prostate [nTPM]":"24.0","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"12.4","Tissue RNA - skeletal muscle [nTPM]":"29.0","Tissue RNA - skin 1 [nTPM]":"27.6","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"28.4","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"23.3","Tissue RNA - testis [nTPM]":"17.5","Tissue RNA - thalamus [nTPM]":"40.4","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"19.5","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"20.2","Tissue RNA - vagina [nTPM]":"19.6","Tissue RNA - white matter [nTPM]":"58.7","Cell RNA - A-431 [nTPM]":"70.4","Cell RNA - A549 [nTPM]":"22.2","Cell RNA - AF22 [nTPM]":"70.9","Cell RNA - AN3-CA [nTPM]":"30.6","Cell RNA - ASC diff [nTPM]":"94.1","Cell RNA - ASC TERT1 [nTPM]":"90.6","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"26.8","Cell RNA - BJ hTERT+ [nTPM]":"186.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.7","Cell RNA - CACO-2 [nTPM]":"73.9","Cell RNA - CAPAN-2 [nTPM]":"54.4","Cell RNA - Daudi [nTPM]":"15.4","Cell RNA - EFO-21 [nTPM]":"22.3","Cell RNA - fHDF\/TERT166 [nTPM]":"51.7","Cell RNA - GAMG [nTPM]":"234.6","Cell RNA - HaCaT [nTPM]":"32.7","Cell RNA - HAP1 [nTPM]":"63.2","Cell RNA - HBEC3-KT [nTPM]":"110.9","Cell RNA - HBF TERT88 [nTPM]":"12.9","Cell RNA - HDLM-2 [nTPM]":"14.9","Cell RNA - HEK 293 [nTPM]":"34.5","Cell RNA - HEL [nTPM]":"37.7","Cell RNA - HeLa [nTPM]":"38.6","Cell RNA - Hep G2 [nTPM]":"48.3","Cell RNA - HHSteC [nTPM]":"85.5","Cell RNA - HL-60 [nTPM]":"13.7","Cell RNA - HMC-1 [nTPM]":"25.1","Cell RNA - HSkMC [nTPM]":"89.0","Cell RNA - hTCEpi [nTPM]":"41.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"59.7","Cell RNA - hTERT-HME1 [nTPM]":"25.6","Cell RNA - hTERT-RPE1 [nTPM]":"22.2","Cell RNA - HUVEC TERT2 [nTPM]":"26.9","Cell RNA - JURKAT [nTPM]":"72.1","Cell RNA - K-562 [nTPM]":"37.4","Cell RNA - Karpas-707 [nTPM]":"87.3","Cell RNA - LHCN-M2 [nTPM]":"27.8","Cell RNA - MCF7 [nTPM]":"23.8","Cell RNA - MOLT-4 [nTPM]":"29.9","Cell RNA - NB-4 [nTPM]":"19.7","Cell RNA - NTERA-2 [nTPM]":"115.4","Cell RNA - OE19 [nTPM]":"11.3","Cell RNA - PC-3 [nTPM]":"20.1","Cell RNA - REH [nTPM]":"34.9","Cell RNA - RH-30 [nTPM]":"21.9","Cell RNA - RPMI-8226 [nTPM]":"92.2","Cell RNA - RPTEC TERT1 [nTPM]":"82.8","Cell RNA - RT4 [nTPM]":"38.1","Cell RNA - SCLC-21H [nTPM]":"41.4","Cell RNA - SH-SY5Y [nTPM]":"36.7","Cell RNA - SiHa [nTPM]":"31.4","Cell RNA - SK-BR-3 [nTPM]":"24.0","Cell RNA - SK-MEL-30 [nTPM]":"27.5","Cell RNA - SuSa [nTPM]":"30.6","Cell RNA - T-47d [nTPM]":"38.0","Cell RNA - THP-1 [nTPM]":"33.7","Cell RNA - TIME [nTPM]":"40.8","Cell RNA - U-138 MG [nTPM]":"37.9","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"33.8","Cell RNA - U-251 MG [nTPM]":"21.1","Cell RNA - U-266\/70 [nTPM]":"31.8","Cell RNA - U-266\/84 [nTPM]":"29.5","Cell RNA - U-698 [nTPM]":"30.6","Cell RNA - U-87 MG [nTPM]":"39.7","Cell RNA - U-937 [nTPM]":"59.4","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"3.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.9","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"20.0","Brain RNA - basal ganglia [nTPM]":"30.8","Brain RNA - cerebellum [nTPM]":"38.9","Brain RNA - cerebral cortex [nTPM]":"33.5","Brain RNA - hippocampal formation [nTPM]":"15.7","Brain RNA - hypothalamus [nTPM]":"26.2","Brain RNA - medulla oblongata [nTPM]":"62.3","Brain RNA - midbrain [nTPM]":"40.7","Brain RNA - pons [nTPM]":"65.7","Brain RNA - spinal cord [nTPM]":"28.4","Brain RNA - thalamus [nTPM]":"40.4","Brain RNA - white matter [nTPM]":"58.7","Single Cell Type RNA - Adipocytes [nTPM]":"13.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.8","Single Cell Type RNA - Astrocytes [nTPM]":"66.6","Single Cell Type RNA - B-cells [nTPM]":"7.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"16.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"18.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.5","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.4","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.7","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"20.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"132.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"13.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"4.9","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"158.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"6.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"20.3","Single Cell Type RNA - Spermatogonia [nTPM]":"18.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"18.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"LYZ","Gene synonym":[],"Ensembl":"ENSG00000090382","Gene description":"Lysozyme","Uniprot":["P61626"],"Chromosome":"12","Position":"69348381-69354234","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Antimicrobial","Bacteriolytic enzyme","Glycosidase","Hydrolase"],"Disease involvement":["Amyloidosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"10588.1","salivary gland":"21115.5","stomach 1":"8941.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"3106.1","Kupffer cells":"2841.2","Langerhans cells":"4859.1","Macrophages":"4870.7","monocytes":"7063.0","Pancreatic endocrine cells":"3152.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"976.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"25266.2","myeloid DC":"14438.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"dendritic cells":"14438.7","monocytes":"25266.2"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"OE19":"12130.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000055","HPA048284","HPA066182"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Actin filaments"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1500000000,"Blood concentration - Conc. blood MS [pg\/L]":"1500000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Golgi apparatus","Actin filaments"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB000055":"AB_2341230","HPA048284":"AB_2680339","HPA066182":"AB_2732741"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.45e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"95.8","Tissue RNA - adrenal gland [nTPM]":"27.8","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"802.1","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"10588.1","Tissue RNA - breast [nTPM]":"128.2","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"18.5","Tissue RNA - cervix [nTPM]":"156.2","Tissue RNA - choroid plexus [nTPM]":"11.4","Tissue RNA - colon [nTPM]":"309.0","Tissue RNA - duodenum [nTPM]":"3605.0","Tissue RNA - endometrium 1 [nTPM]":"65.7","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"106.3","Tissue RNA - fallopian tube [nTPM]":"33.9","Tissue RNA - gallbladder [nTPM]":"1054.6","Tissue RNA - heart muscle [nTPM]":"34.8","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"4.3","Tissue RNA - kidney [nTPM]":"32.4","Tissue RNA - liver [nTPM]":"138.0","Tissue RNA - lung [nTPM]":"1355.2","Tissue RNA - lymph node [nTPM]":"739.7","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"20.4","Tissue RNA - pancreas [nTPM]":"63.1","Tissue RNA - parathyroid gland [nTPM]":"13.8","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"91.3","Tissue RNA - pons [nTPM]":"12.2","Tissue RNA - prostate [nTPM]":"40.2","Tissue RNA - rectum [nTPM]":"273.8","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"21115.5","Tissue RNA - seminal vesicle [nTPM]":"21.8","Tissue RNA - skeletal muscle [nTPM]":"34.0","Tissue RNA - skin 1 [nTPM]":"58.7","Tissue RNA - small intestine [nTPM]":"1322.2","Tissue RNA - smooth muscle [nTPM]":"123.9","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"621.0","Tissue RNA - stomach 1 [nTPM]":"8941.1","Tissue RNA - testis [nTPM]":"21.8","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"321.8","Tissue RNA - thyroid gland [nTPM]":"27.8","Tissue RNA - tongue [nTPM]":"36.4","Tissue RNA - tonsil [nTPM]":"652.8","Tissue RNA - urinary bladder [nTPM]":"428.5","Tissue RNA - vagina [nTPM]":"16.2","Tissue RNA - white matter [nTPM]":"11.7","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"4.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"9.5","Cell RNA - CAPAN-2 [nTPM]":"6.5","Cell RNA - Daudi [nTPM]":"4.2","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.6","Cell RNA - HaCaT [nTPM]":"1.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"62.4","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"960.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"110.6","Cell RNA - HMC-1 [nTPM]":"50.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"2.6","Cell RNA - NB-4 [nTPM]":"109.5","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"12130.8","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"16.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"3.6","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"489.0","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.6","Cell RNA - U-2197 [nTPM]":"2.3","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"2.6","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"1.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"518.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"443.4","Blood RNA - classical monocyte [nTPM]":"25266.2","Blood RNA - eosinophil [nTPM]":"298.2","Blood RNA - gdT-cell [nTPM]":"32.6","Blood RNA - intermediate monocyte [nTPM]":"4798.4","Blood RNA - MAIT T-cell [nTPM]":"52.3","Blood RNA - memory B-cell [nTPM]":"100.5","Blood RNA - memory CD4 T-cell [nTPM]":"20.1","Blood RNA - memory CD8 T-cell [nTPM]":"22.7","Blood RNA - myeloid DC [nTPM]":"14438.7","Blood RNA - naive B-cell [nTPM]":"20.8","Blood RNA - naive CD4 T-cell [nTPM]":"20.0","Blood RNA - naive CD8 T-cell [nTPM]":"17.8","Blood RNA - neutrophil [nTPM]":"1007.7","Blood RNA - NK-cell [nTPM]":"108.1","Blood RNA - non-classical monocyte [nTPM]":"880.1","Blood RNA - plasmacytoid DC [nTPM]":"301.2","Blood RNA - T-reg [nTPM]":"31.1","Blood RNA - total PBMC [nTPM]":"25392.1","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"18.5","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"4.3","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"12.2","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"11.7","Single Cell Type RNA - Adipocytes [nTPM]":"24.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"285.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"80.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"57.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1205.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"734.9","Single Cell Type RNA - Club cells [nTPM]":"51.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"39.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"55.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.9","Single Cell Type RNA - Endothelial cells [nTPM]":"25.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"264.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"547.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.4","Single Cell Type RNA - Fibroblasts [nTPM]":"26.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3106.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"123.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"25.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"887.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"112.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2841.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4859.1","Single Cell Type RNA - Late spermatids [nTPM]":"17.4","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"4870.7","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"7063.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"176.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3152.5","Single Cell Type RNA - Paneth cells [nTPM]":"600.5","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"3.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - T-cells [nTPM]":"50.6","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"111.4","Single Cell Type RNA - Urothelial cells [nTPM]":"38.3"},{"Gene":"MAF","Gene synonym":["c-MAF"],"Ensembl":"ENSG00000178573","Gene description":"MAF bZIP transcription factor","Uniprot":["O75444"],"Chromosome":"16","Position":"79585843-79600737","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Cataract","Deafness","Disease variant","Dwarfism","Mental retardation","Proto-oncogene","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatic stellate cells":"407.6","Hofbauer cells":"273.6","Inhibitory neurons":"378.7","Kupffer cells":"394.7","Proximal enterocytes":"288.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"38.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"38.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"Karpas-707":"207.0","RPMI-8226":"355.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010296","HPA028289"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010296":"AB_638562","HPA028289":"AB_10602024"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.74e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-3"},"Tissue RNA - adipose tissue [nTPM]":"27.8","Tissue RNA - adrenal gland [nTPM]":"15.4","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"20.7","Tissue RNA - basal ganglia [nTPM]":"14.5","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"17.3","Tissue RNA - cerebellum [nTPM]":"10.3","Tissue RNA - cerebral cortex [nTPM]":"13.5","Tissue RNA - cervix [nTPM]":"35.0","Tissue RNA - choroid plexus [nTPM]":"14.2","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"70.3","Tissue RNA - endometrium 1 [nTPM]":"23.5","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"22.6","Tissue RNA - fallopian tube [nTPM]":"20.1","Tissue RNA - gallbladder [nTPM]":"16.7","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"13.7","Tissue RNA - hypothalamus [nTPM]":"13.0","Tissue RNA - kidney [nTPM]":"48.2","Tissue RNA - liver [nTPM]":"25.7","Tissue RNA - lung [nTPM]":"18.8","Tissue RNA - lymph node [nTPM]":"30.9","Tissue RNA - medulla oblongata [nTPM]":"19.0","Tissue RNA - midbrain [nTPM]":"22.6","Tissue RNA - ovary [nTPM]":"39.2","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"50.8","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"36.1","Tissue RNA - pons [nTPM]":"17.6","Tissue RNA - prostate [nTPM]":"18.4","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"15.4","Tissue RNA - skeletal muscle [nTPM]":"49.6","Tissue RNA - skin 1 [nTPM]":"57.8","Tissue RNA - small intestine [nTPM]":"83.0","Tissue RNA - smooth muscle [nTPM]":"17.8","Tissue RNA - spinal cord [nTPM]":"18.7","Tissue RNA - spleen [nTPM]":"26.0","Tissue RNA - stomach 1 [nTPM]":"13.0","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"28.7","Tissue RNA - thymus [nTPM]":"17.9","Tissue RNA - thyroid gland [nTPM]":"23.1","Tissue RNA - tongue [nTPM]":"19.8","Tissue RNA - tonsil [nTPM]":"23.9","Tissue RNA - urinary bladder [nTPM]":"17.7","Tissue RNA - vagina [nTPM]":"30.5","Tissue RNA - white matter [nTPM]":"29.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"22.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"2.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"7.2","Cell RNA - HEK 293 [nTPM]":"8.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"14.3","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"6.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"207.0","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"13.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"6.2","Cell RNA - RPMI-8226 [nTPM]":"355.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.9","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"8.7","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"6.9","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"38.1","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"8.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"4.7","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"14.5","Brain RNA - cerebellum [nTPM]":"10.3","Brain RNA - cerebral cortex [nTPM]":"13.5","Brain RNA - hippocampal formation [nTPM]":"13.7","Brain RNA - hypothalamus [nTPM]":"13.0","Brain RNA - medulla oblongata [nTPM]":"19.0","Brain RNA - midbrain [nTPM]":"22.6","Brain RNA - pons [nTPM]":"17.6","Brain RNA - spinal cord [nTPM]":"18.7","Brain RNA - thalamus [nTPM]":"28.7","Brain RNA - white matter [nTPM]":"29.8","Single Cell Type RNA - Adipocytes [nTPM]":"40.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.6","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"10.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"88.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"9.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"7.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.7","Single Cell Type RNA - dendritic cells [nTPM]":"71.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"114.1","Single Cell Type RNA - Endothelial cells [nTPM]":"42.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"73.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.6","Single Cell Type RNA - granulocytes [nTPM]":"22.1","Single Cell Type RNA - Granulosa cells [nTPM]":"73.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"407.6","Single Cell Type RNA - Hepatocytes [nTPM]":"63.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"273.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"378.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.9","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"394.7","Single Cell Type RNA - Langerhans cells [nTPM]":"57.9","Single Cell Type RNA - Late spermatids [nTPM]":"9.0","Single Cell Type RNA - Leydig cells [nTPM]":"149.8","Single Cell Type RNA - Macrophages [nTPM]":"127.2","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"122.7","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"78.1","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"67.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.0","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"115.1","Single Cell Type RNA - Plasma cells [nTPM]":"48.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"288.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"146.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"40.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"107.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"141.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"122.2","Single Cell Type RNA - Theca cells [nTPM]":"28.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.1","Single Cell Type RNA - Urothelial cells [nTPM]":"5.4"},{"Gene":"MAG","Gene synonym":["GMA","S-MAG","SIGLEC-4A","SIGLEC4A"],"Ensembl":"ENSG00000105695","Gene description":"Myelin associated glycoprotein","Uniprot":["P20916"],"Chromosome":"19","Position":"35292125-35313807","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"33","RNA tissue specific nTPM":{"brain":"731.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Oligodendrocytes":"267.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"20.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"plasmacytoid DC":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"2.9"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"22","RNA cell line specific nTPM":{"WM-115":"36.6"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"2742.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009345","HPA012499"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009345":"AB_670104","HPA012499":"AB_1854238"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"121.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"366.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"314.0","Tissue RNA - cerebral cortex [nTPM]":"237.4","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"4.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"157.7","Tissue RNA - hypothalamus [nTPM]":"195.2","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"459.9","Tissue RNA - midbrain [nTPM]":"317.3","Tissue RNA - ovary [nTPM]":"22.4","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"417.5","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"247.8","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"303.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"731.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"1.6","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"36.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"121.5","Brain RNA - basal ganglia [nTPM]":"366.4","Brain RNA - cerebellum [nTPM]":"314.0","Brain RNA - cerebral cortex [nTPM]":"237.4","Brain RNA - hippocampal formation [nTPM]":"157.7","Brain RNA - hypothalamus [nTPM]":"195.2","Brain RNA - medulla oblongata [nTPM]":"459.9","Brain RNA - midbrain [nTPM]":"317.3","Brain RNA - pons [nTPM]":"417.5","Brain RNA - spinal cord [nTPM]":"247.8","Brain RNA - thalamus [nTPM]":"303.0","Brain RNA - white matter [nTPM]":"731.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"4.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.4","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"21.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"267.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"11.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MAK","Gene synonym":["dJ417M14.2","RP62"],"Ensembl":"ENSG00000111837","Gene description":"Male germ cell associated kinase","Uniprot":["P20794"],"Chromosome":"6","Position":"10762723-10838553","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"retina":"118.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"369.1","Early spermatids":"119.7","Rod photoreceptor cells":"330.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"neutrophil":"6.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"6.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"1.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"5.4","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"118.9","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"6.3","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"14.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"369.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"119.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"47.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"23.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"48.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"330.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"15.2","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"MAPK10","Gene synonym":["JNK3","p493F12","p54bSAPK","PRKM10"],"Ensembl":"ENSG00000109339","Gene description":"Mitogen-activated protein kinase 10","Uniprot":["P53779"],"Chromosome":"4","Position":"85990007-86594625","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Biological rhythms"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"91.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"902.0","Excitatory neurons":"1018.9","Inhibitory neurons":"727.8","Late spermatids":"400.5","Oligodendrocyte precursor cells":"596.6","Oligodendrocytes":"302.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"AF22":"155.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022625"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022625":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.57e-4"},"Tissue RNA - adipose tissue [nTPM]":"26.1","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"45.2","Tissue RNA - appendix [nTPM]":"5.1","Tissue RNA - basal ganglia [nTPM]":"61.6","Tissue RNA - bone marrow [nTPM]":"14.5","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"25.4","Tissue RNA - cerebral cortex [nTPM]":"91.3","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"23.5","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"14.5","Tissue RNA - epididymis [nTPM]":"18.8","Tissue RNA - esophagus [nTPM]":"9.8","Tissue RNA - fallopian tube [nTPM]":"15.8","Tissue RNA - gallbladder [nTPM]":"13.8","Tissue RNA - heart muscle [nTPM]":"6.9","Tissue RNA - hippocampal formation [nTPM]":"60.4","Tissue RNA - hypothalamus [nTPM]":"24.9","Tissue RNA - kidney [nTPM]":"20.4","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"8.6","Tissue RNA - lymph node [nTPM]":"5.2","Tissue RNA - medulla oblongata [nTPM]":"29.0","Tissue RNA - midbrain [nTPM]":"36.2","Tissue RNA - ovary [nTPM]":"14.7","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"10.3","Tissue RNA - pituitary gland [nTPM]":"25.5","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"31.4","Tissue RNA - prostate [nTPM]":"22.4","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"18.3","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"24.2","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"15.5","Tissue RNA - spinal cord [nTPM]":"24.9","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"6.6","Tissue RNA - testis [nTPM]":"26.4","Tissue RNA - thalamus [nTPM]":"39.2","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"20.5","Tissue RNA - tongue [nTPM]":"4.2","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"14.0","Tissue RNA - vagina [nTPM]":"18.4","Tissue RNA - white matter [nTPM]":"55.6","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"155.0","Cell RNA - AN3-CA [nTPM]":"4.8","Cell RNA - ASC diff [nTPM]":"4.1","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"5.6","Cell RNA - BJ [nTPM]":"3.2","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"4.4","Cell RNA - Daudi [nTPM]":"7.1","Cell RNA - EFO-21 [nTPM]":"5.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"3.8","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"4.2","Cell RNA - HBF TERT88 [nTPM]":"4.3","Cell RNA - HDLM-2 [nTPM]":"4.9","Cell RNA - HEK 293 [nTPM]":"4.0","Cell RNA - HEL [nTPM]":"5.7","Cell RNA - HeLa [nTPM]":"7.3","Cell RNA - Hep G2 [nTPM]":"4.6","Cell RNA - HHSteC [nTPM]":"3.6","Cell RNA - HL-60 [nTPM]":"2.7","Cell RNA - HMC-1 [nTPM]":"3.1","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.7","Cell RNA - hTERT-HME1 [nTPM]":"5.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.5","Cell RNA - HUVEC TERT2 [nTPM]":"3.5","Cell RNA - JURKAT [nTPM]":"4.8","Cell RNA - K-562 [nTPM]":"5.2","Cell RNA - Karpas-707 [nTPM]":"27.9","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"3.5","Cell RNA - MOLT-4 [nTPM]":"4.4","Cell RNA - NB-4 [nTPM]":"3.1","Cell RNA - NTERA-2 [nTPM]":"8.8","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"4.9","Cell RNA - RH-30 [nTPM]":"4.0","Cell RNA - RPMI-8226 [nTPM]":"2.5","Cell RNA - RPTEC TERT1 [nTPM]":"10.7","Cell RNA - RT4 [nTPM]":"16.9","Cell RNA - SCLC-21H [nTPM]":"9.2","Cell RNA - SH-SY5Y [nTPM]":"8.4","Cell RNA - SiHa [nTPM]":"3.3","Cell RNA - SK-BR-3 [nTPM]":"5.9","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"8.8","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"7.5","Cell RNA - U-138 MG [nTPM]":"6.3","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"3.0","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"8.2","Cell RNA - U-266\/84 [nTPM]":"5.1","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"9.9","Cell RNA - U-937 [nTPM]":"3.5","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"4.4","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"45.2","Brain RNA - basal ganglia [nTPM]":"61.6","Brain RNA - cerebellum [nTPM]":"25.4","Brain RNA - cerebral cortex [nTPM]":"91.3","Brain RNA - hippocampal formation [nTPM]":"60.4","Brain RNA - hypothalamus [nTPM]":"24.9","Brain RNA - medulla oblongata [nTPM]":"29.0","Brain RNA - midbrain [nTPM]":"36.2","Brain RNA - pons [nTPM]":"31.4","Brain RNA - spinal cord [nTPM]":"24.9","Brain RNA - thalamus [nTPM]":"39.2","Brain RNA - white matter [nTPM]":"55.6","Single Cell Type RNA - Adipocytes [nTPM]":"4.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.8","Single Cell Type RNA - Astrocytes [nTPM]":"902.0","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"26.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"12.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"2.4","Single Cell Type RNA - Early spermatids [nTPM]":"219.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"61.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1018.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"16.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"727.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"400.5","Single Cell Type RNA - Leydig cells [nTPM]":"26.4","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"185.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"596.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"302.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"54.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"68.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.5","Single Cell Type RNA - Spermatocytes [nTPM]":"10.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"28.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"22.6"},{"Gene":"MAPKAPK3","Gene synonym":["3pK","MAPKAP3","MK-3","MK3"],"Ensembl":"ENSG00000114738","Gene description":"MAPK activated protein kinase 3","Uniprot":["Q16644"],"Chromosome":"3","Position":"50611520-50649291","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"106.5","heart muscle":"256.3","skeletal muscle":"224.2","tongue":"284.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"226.6","Hofbauer cells":"102.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"142.8","granulocytes":"126.3","monocytes":"341.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058275"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA058275":"AB_2683663"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.08e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.90e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.3","Tissue RNA - adrenal gland [nTPM]":"43.3","Tissue RNA - amygdala [nTPM]":"18.0","Tissue RNA - appendix [nTPM]":"29.8","Tissue RNA - basal ganglia [nTPM]":"19.6","Tissue RNA - bone marrow [nTPM]":"106.5","Tissue RNA - breast [nTPM]":"15.8","Tissue RNA - cerebellum [nTPM]":"19.2","Tissue RNA - cerebral cortex [nTPM]":"19.2","Tissue RNA - cervix [nTPM]":"15.0","Tissue RNA - choroid plexus [nTPM]":"21.3","Tissue RNA - colon [nTPM]":"19.7","Tissue RNA - duodenum [nTPM]":"30.2","Tissue RNA - endometrium 1 [nTPM]":"11.3","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"49.6","Tissue RNA - fallopian tube [nTPM]":"15.1","Tissue RNA - gallbladder [nTPM]":"12.1","Tissue RNA - heart muscle [nTPM]":"256.3","Tissue RNA - hippocampal formation [nTPM]":"18.0","Tissue RNA - hypothalamus [nTPM]":"19.7","Tissue RNA - kidney [nTPM]":"40.0","Tissue RNA - liver [nTPM]":"18.7","Tissue RNA - lung [nTPM]":"28.2","Tissue RNA - lymph node [nTPM]":"21.7","Tissue RNA - medulla oblongata [nTPM]":"23.6","Tissue RNA - midbrain [nTPM]":"20.5","Tissue RNA - ovary [nTPM]":"14.2","Tissue RNA - pancreas [nTPM]":"36.2","Tissue RNA - parathyroid gland [nTPM]":"47.2","Tissue RNA - pituitary gland [nTPM]":"23.5","Tissue RNA - placenta [nTPM]":"13.9","Tissue RNA - pons [nTPM]":"22.5","Tissue RNA - prostate [nTPM]":"18.4","Tissue RNA - rectum [nTPM]":"20.0","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"27.7","Tissue RNA - seminal vesicle [nTPM]":"12.6","Tissue RNA - skeletal muscle [nTPM]":"224.2","Tissue RNA - skin 1 [nTPM]":"53.4","Tissue RNA - small intestine [nTPM]":"24.2","Tissue RNA - smooth muscle [nTPM]":"15.9","Tissue RNA - spinal cord [nTPM]":"21.6","Tissue RNA - spleen [nTPM]":"25.3","Tissue RNA - stomach 1 [nTPM]":"27.6","Tissue RNA - testis [nTPM]":"9.2","Tissue RNA - thalamus [nTPM]":"21.1","Tissue RNA - thymus [nTPM]":"42.0","Tissue RNA - thyroid gland [nTPM]":"41.2","Tissue RNA - tongue [nTPM]":"284.3","Tissue RNA - tonsil [nTPM]":"24.2","Tissue RNA - urinary bladder [nTPM]":"20.3","Tissue RNA - vagina [nTPM]":"22.2","Tissue RNA - white matter [nTPM]":"21.6","Cell RNA - A-431 [nTPM]":"99.6","Cell RNA - A549 [nTPM]":"30.3","Cell RNA - AF22 [nTPM]":"12.4","Cell RNA - AN3-CA [nTPM]":"35.9","Cell RNA - ASC diff [nTPM]":"18.4","Cell RNA - ASC TERT1 [nTPM]":"45.7","Cell RNA - BEWO [nTPM]":"27.9","Cell RNA - BJ [nTPM]":"23.8","Cell RNA - BJ hTERT+ [nTPM]":"33.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.3","Cell RNA - CACO-2 [nTPM]":"47.1","Cell RNA - CAPAN-2 [nTPM]":"90.2","Cell RNA - Daudi [nTPM]":"39.8","Cell RNA - EFO-21 [nTPM]":"23.5","Cell RNA - fHDF\/TERT166 [nTPM]":"79.5","Cell RNA - GAMG [nTPM]":"88.5","Cell RNA - HaCaT [nTPM]":"34.6","Cell RNA - HAP1 [nTPM]":"85.9","Cell RNA - HBEC3-KT [nTPM]":"92.7","Cell RNA - HBF TERT88 [nTPM]":"31.9","Cell RNA - HDLM-2 [nTPM]":"88.3","Cell RNA - HEK 293 [nTPM]":"22.3","Cell RNA - HEL [nTPM]":"209.5","Cell RNA - HeLa [nTPM]":"40.6","Cell RNA - Hep G2 [nTPM]":"43.5","Cell RNA - HHSteC [nTPM]":"36.8","Cell RNA - HL-60 [nTPM]":"152.1","Cell RNA - HMC-1 [nTPM]":"106.4","Cell RNA - HSkMC [nTPM]":"36.9","Cell RNA - hTCEpi [nTPM]":"57.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"83.1","Cell RNA - hTERT-HME1 [nTPM]":"112.2","Cell RNA - hTERT-RPE1 [nTPM]":"35.6","Cell RNA - HUVEC TERT2 [nTPM]":"31.9","Cell RNA - JURKAT [nTPM]":"70.2","Cell RNA - K-562 [nTPM]":"59.7","Cell RNA - Karpas-707 [nTPM]":"25.4","Cell RNA - LHCN-M2 [nTPM]":"76.1","Cell RNA - MCF7 [nTPM]":"40.5","Cell RNA - MOLT-4 [nTPM]":"65.3","Cell RNA - NB-4 [nTPM]":"153.3","Cell RNA - NTERA-2 [nTPM]":"46.4","Cell RNA - OE19 [nTPM]":"34.6","Cell RNA - PC-3 [nTPM]":"127.0","Cell RNA - REH [nTPM]":"28.5","Cell RNA - RH-30 [nTPM]":"29.9","Cell RNA - RPMI-8226 [nTPM]":"60.1","Cell RNA - RPTEC TERT1 [nTPM]":"165.5","Cell RNA - RT4 [nTPM]":"56.2","Cell RNA - SCLC-21H [nTPM]":"23.0","Cell RNA - SH-SY5Y [nTPM]":"16.5","Cell RNA - SiHa [nTPM]":"21.3","Cell RNA - SK-BR-3 [nTPM]":"58.9","Cell RNA - SK-MEL-30 [nTPM]":"27.7","Cell RNA - SuSa [nTPM]":"20.6","Cell RNA - T-47d [nTPM]":"37.8","Cell RNA - THP-1 [nTPM]":"93.4","Cell RNA - TIME [nTPM]":"23.8","Cell RNA - U-138 MG [nTPM]":"28.1","Cell RNA - U-2 OS [nTPM]":"64.5","Cell RNA - U-2197 [nTPM]":"146.4","Cell RNA - U-251 MG [nTPM]":"59.5","Cell RNA - U-266\/70 [nTPM]":"17.2","Cell RNA - U-266\/84 [nTPM]":"33.7","Cell RNA - U-698 [nTPM]":"33.1","Cell RNA - U-87 MG [nTPM]":"148.3","Cell RNA - U-937 [nTPM]":"234.7","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"45.3","Blood RNA - classical monocyte [nTPM]":"169.5","Blood RNA - eosinophil [nTPM]":"126.3","Blood RNA - gdT-cell [nTPM]":"27.6","Blood RNA - intermediate monocyte [nTPM]":"271.6","Blood RNA - MAIT T-cell [nTPM]":"27.3","Blood RNA - memory B-cell [nTPM]":"15.1","Blood RNA - memory CD4 T-cell [nTPM]":"30.9","Blood RNA - memory CD8 T-cell [nTPM]":"32.1","Blood RNA - myeloid DC [nTPM]":"142.8","Blood RNA - naive B-cell [nTPM]":"8.8","Blood RNA - naive CD4 T-cell [nTPM]":"23.9","Blood RNA - naive CD8 T-cell [nTPM]":"27.8","Blood RNA - neutrophil [nTPM]":"104.4","Blood RNA - NK-cell [nTPM]":"42.1","Blood RNA - non-classical monocyte [nTPM]":"341.5","Blood RNA - plasmacytoid DC [nTPM]":"91.2","Blood RNA - T-reg [nTPM]":"28.0","Blood RNA - total PBMC [nTPM]":"132.6","Brain RNA - amygdala [nTPM]":"18.0","Brain RNA - basal ganglia [nTPM]":"19.6","Brain RNA - cerebellum [nTPM]":"19.2","Brain RNA - cerebral cortex [nTPM]":"19.2","Brain RNA - hippocampal formation [nTPM]":"18.0","Brain RNA - hypothalamus [nTPM]":"19.7","Brain RNA - medulla oblongata [nTPM]":"23.6","Brain RNA - midbrain [nTPM]":"20.5","Brain RNA - pons [nTPM]":"22.5","Brain RNA - spinal cord [nTPM]":"21.6","Brain RNA - thalamus [nTPM]":"21.1","Brain RNA - white matter [nTPM]":"21.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"8.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"226.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"10.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - dendritic cells [nTPM]":"38.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"64.6","Single Cell Type RNA - Ductal cells [nTPM]":"45.6","Single Cell Type RNA - Early spermatids [nTPM]":"34.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"14.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.4","Single Cell Type RNA - granulocytes [nTPM]":"36.2","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"14.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"102.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"68.0","Single Cell Type RNA - Langerhans cells [nTPM]":"23.9","Single Cell Type RNA - Late spermatids [nTPM]":"86.2","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"59.4","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"76.6","Single Cell Type RNA - Muller glia cells [nTPM]":"17.1","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"76.2","Single Cell Type RNA - Paneth cells [nTPM]":"15.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"24.3","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.2","Single Cell Type RNA - Urothelial cells [nTPM]":"33.5"},{"Gene":"MAPT","Gene synonym":["DDPAC","FLJ31424","FTDP-17","MAPTL","MGC138549","MSTD","MTBT1","MTBT2","PPND","PPP1R103","tau"],"Ensembl":"ENSG00000186868","Gene description":"Microtubule associated protein tau","Uniprot":["P10636"],"Chromosome":"17","Position":"45894527-46028334","Protein class":["Candidate cardiovascular disease genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Alzheimer disease","Disease variant","FDA approved drug targets","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"67.7","skeletal muscle":"79.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"142.4","Bipolar cells":"314.4","Early spermatids":"199.9","Excitatory neurons":"189.2","Horizontal cells":"361.7","Inhibitory neurons":"153.7","Late spermatids":"416.6","Muller glia cells":"145.7","Oligodendrocytes":"163.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"9.5","glioma":"13.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"HDLM-2":"69.0","SCLC-21H":"21.1","T-47d":"34.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000151","HPA048895","HPA069524","HPA069570","CAB072344"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7100","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"CAB000151":null,"CAB072344":null,"HPA048895":"AB_2680550","HPA069524":"AB_2686145","HPA069570":"AB_2686155"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"4.3","Tissue RNA - amygdala [nTPM]":"26.2","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"27.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"9.1","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"67.7","Tissue RNA - cervix [nTPM]":"2.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"8.4","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"30.0","Tissue RNA - hypothalamus [nTPM]":"20.4","Tissue RNA - kidney [nTPM]":"14.7","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"11.6","Tissue RNA - midbrain [nTPM]":"11.4","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"29.5","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"22.4","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"17.6","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"79.0","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"20.3","Tissue RNA - thalamus [nTPM]":"14.8","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"27.4","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"10.2","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"19.7","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"6.4","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"2.3","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"69.0","Cell RNA - HEK 293 [nTPM]":"3.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"4.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"4.4","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"3.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"7.7","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"2.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"4.0","Cell RNA - RPMI-8226 [nTPM]":"8.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"9.1","Cell RNA - SCLC-21H [nTPM]":"21.1","Cell RNA - SH-SY5Y [nTPM]":"9.1","Cell RNA - SiHa [nTPM]":"2.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"34.7","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"26.2","Brain RNA - basal ganglia [nTPM]":"27.1","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"67.7","Brain RNA - hippocampal formation [nTPM]":"30.0","Brain RNA - hypothalamus [nTPM]":"20.4","Brain RNA - medulla oblongata [nTPM]":"11.6","Brain RNA - midbrain [nTPM]":"11.4","Brain RNA - pons [nTPM]":"22.4","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"14.8","Brain RNA - white matter [nTPM]":"19.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.8","Single Cell Type RNA - Astrocytes [nTPM]":"142.4","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"314.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"199.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"189.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"361.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"153.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"416.6","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"145.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"129.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"163.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"76.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"18.4","Single Cell Type RNA - Spermatogonia [nTPM]":"8.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"MARCHF6","Gene synonym":["MARCH-VI","MARCH6","RNF176","TEB4"],"Ensembl":"ENSG00000145495","Gene description":"Membrane associated ring-CH-type finger 6","Uniprot":["O60337"],"Chromosome":"5","Position":"10353695-10440388","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"38.5","Cardiomyocytes":"102.5","Cytotrophoblasts":"54.4","dendritic cells":"25.8","Extravillous trophoblasts":"30.0","Hofbauer cells":"36.4","Syncytiotrophoblasts":"81.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040841","HPA063246"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA040841":"AB_2677162","HPA063246":"AB_2684970"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"},"Tissue RNA - adipose tissue [nTPM]":"22.1","Tissue RNA - adrenal gland [nTPM]":"25.5","Tissue RNA - amygdala [nTPM]":"16.1","Tissue RNA - appendix [nTPM]":"20.3","Tissue RNA - basal ganglia [nTPM]":"23.7","Tissue RNA - bone marrow [nTPM]":"76.5","Tissue RNA - breast [nTPM]":"25.9","Tissue RNA - cerebellum [nTPM]":"28.3","Tissue RNA - cerebral cortex [nTPM]":"20.7","Tissue RNA - cervix [nTPM]":"20.1","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"26.9","Tissue RNA - duodenum [nTPM]":"32.8","Tissue RNA - endometrium 1 [nTPM]":"22.7","Tissue RNA - epididymis [nTPM]":"25.5","Tissue RNA - esophagus [nTPM]":"20.9","Tissue RNA - fallopian tube [nTPM]":"24.9","Tissue RNA - gallbladder [nTPM]":"24.5","Tissue RNA - heart muscle [nTPM]":"30.8","Tissue RNA - hippocampal formation [nTPM]":"22.0","Tissue RNA - hypothalamus [nTPM]":"30.4","Tissue RNA - kidney [nTPM]":"34.1","Tissue RNA - liver [nTPM]":"32.5","Tissue RNA - lung [nTPM]":"25.1","Tissue RNA - lymph node [nTPM]":"24.7","Tissue RNA - medulla oblongata [nTPM]":"13.7","Tissue RNA - midbrain [nTPM]":"17.5","Tissue RNA - ovary [nTPM]":"36.0","Tissue RNA - pancreas [nTPM]":"39.3","Tissue RNA - parathyroid gland [nTPM]":"62.4","Tissue RNA - pituitary gland [nTPM]":"20.8","Tissue RNA - placenta [nTPM]":"22.8","Tissue RNA - pons [nTPM]":"16.9","Tissue RNA - prostate [nTPM]":"22.7","Tissue RNA - rectum [nTPM]":"19.8","Tissue RNA - retina [nTPM]":"36.6","Tissue RNA - salivary gland [nTPM]":"25.6","Tissue RNA - seminal vesicle [nTPM]":"23.8","Tissue RNA - skeletal muscle [nTPM]":"48.4","Tissue RNA - skin 1 [nTPM]":"24.8","Tissue RNA - small intestine [nTPM]":"30.3","Tissue RNA - smooth muscle [nTPM]":"18.9","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"28.2","Tissue RNA - stomach 1 [nTPM]":"30.2","Tissue RNA - testis [nTPM]":"29.9","Tissue RNA - thalamus [nTPM]":"27.9","Tissue RNA - thymus [nTPM]":"32.3","Tissue RNA - thyroid gland [nTPM]":"29.3","Tissue RNA - tongue [nTPM]":"51.8","Tissue RNA - tonsil [nTPM]":"23.3","Tissue RNA - urinary bladder [nTPM]":"23.7","Tissue RNA - vagina [nTPM]":"18.6","Tissue RNA - white matter [nTPM]":"33.5","Cell RNA - A-431 [nTPM]":"37.4","Cell RNA - A549 [nTPM]":"55.1","Cell RNA - AF22 [nTPM]":"90.1","Cell RNA - AN3-CA [nTPM]":"69.9","Cell RNA - ASC diff [nTPM]":"50.6","Cell RNA - ASC TERT1 [nTPM]":"40.4","Cell RNA - BEWO [nTPM]":"73.7","Cell RNA - BJ [nTPM]":"57.7","Cell RNA - BJ hTERT+ [nTPM]":"53.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"61.8","Cell RNA - CACO-2 [nTPM]":"52.8","Cell RNA - CAPAN-2 [nTPM]":"97.0","Cell RNA - Daudi [nTPM]":"39.4","Cell RNA - EFO-21 [nTPM]":"85.4","Cell RNA - fHDF\/TERT166 [nTPM]":"54.4","Cell RNA - GAMG [nTPM]":"67.2","Cell RNA - HaCaT [nTPM]":"52.3","Cell RNA - HAP1 [nTPM]":"48.2","Cell RNA - HBEC3-KT [nTPM]":"37.7","Cell RNA - HBF TERT88 [nTPM]":"65.4","Cell RNA - HDLM-2 [nTPM]":"82.9","Cell RNA - HEK 293 [nTPM]":"43.0","Cell RNA - HEL [nTPM]":"50.7","Cell RNA - HeLa [nTPM]":"179.7","Cell RNA - Hep G2 [nTPM]":"36.2","Cell RNA - HHSteC [nTPM]":"35.6","Cell RNA - HL-60 [nTPM]":"61.4","Cell RNA - HMC-1 [nTPM]":"54.6","Cell RNA - HSkMC [nTPM]":"47.4","Cell RNA - hTCEpi [nTPM]":"40.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.0","Cell RNA - hTERT-HME1 [nTPM]":"53.1","Cell RNA - hTERT-RPE1 [nTPM]":"50.0","Cell RNA - HUVEC TERT2 [nTPM]":"45.8","Cell RNA - JURKAT [nTPM]":"41.4","Cell RNA - K-562 [nTPM]":"62.1","Cell RNA - Karpas-707 [nTPM]":"85.1","Cell RNA - LHCN-M2 [nTPM]":"45.0","Cell RNA - MCF7 [nTPM]":"42.4","Cell RNA - MOLT-4 [nTPM]":"33.1","Cell RNA - NB-4 [nTPM]":"47.2","Cell RNA - NTERA-2 [nTPM]":"32.8","Cell RNA - OE19 [nTPM]":"29.9","Cell RNA - PC-3 [nTPM]":"38.5","Cell RNA - REH [nTPM]":"50.9","Cell RNA - RH-30 [nTPM]":"37.6","Cell RNA - RPMI-8226 [nTPM]":"57.0","Cell RNA - RPTEC TERT1 [nTPM]":"38.0","Cell RNA - RT4 [nTPM]":"72.4","Cell RNA - SCLC-21H [nTPM]":"38.7","Cell RNA - SH-SY5Y [nTPM]":"56.0","Cell RNA - SiHa [nTPM]":"107.2","Cell RNA - SK-BR-3 [nTPM]":"57.9","Cell RNA - SK-MEL-30 [nTPM]":"38.4","Cell RNA - SuSa [nTPM]":"41.3","Cell RNA - T-47d [nTPM]":"48.2","Cell RNA - THP-1 [nTPM]":"32.5","Cell RNA - TIME [nTPM]":"44.8","Cell RNA - U-138 MG [nTPM]":"58.4","Cell RNA - U-2 OS [nTPM]":"56.8","Cell RNA - U-2197 [nTPM]":"29.1","Cell RNA - U-251 MG [nTPM]":"43.7","Cell RNA - U-266\/70 [nTPM]":"59.3","Cell RNA - U-266\/84 [nTPM]":"94.1","Cell RNA - U-698 [nTPM]":"55.7","Cell RNA - U-87 MG [nTPM]":"43.1","Cell RNA - U-937 [nTPM]":"40.7","Cell RNA - WM-115 [nTPM]":"42.8","Blood RNA - basophil [nTPM]":"15.6","Blood RNA - classical monocyte [nTPM]":"7.4","Blood RNA - eosinophil [nTPM]":"12.6","Blood RNA - gdT-cell [nTPM]":"11.2","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"12.8","Blood RNA - memory B-cell [nTPM]":"11.7","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"11.0","Blood RNA - myeloid DC [nTPM]":"6.3","Blood RNA - naive B-cell [nTPM]":"9.6","Blood RNA - naive CD4 T-cell [nTPM]":"12.5","Blood RNA - naive CD8 T-cell [nTPM]":"12.4","Blood RNA - neutrophil [nTPM]":"12.1","Blood RNA - NK-cell [nTPM]":"9.1","Blood RNA - non-classical monocyte [nTPM]":"11.1","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"9.1","Brain RNA - amygdala [nTPM]":"16.1","Brain RNA - basal ganglia [nTPM]":"23.7","Brain RNA - cerebellum [nTPM]":"28.3","Brain RNA - cerebral cortex [nTPM]":"20.7","Brain RNA - hippocampal formation [nTPM]":"22.0","Brain RNA - hypothalamus [nTPM]":"30.4","Brain RNA - medulla oblongata [nTPM]":"13.7","Brain RNA - midbrain [nTPM]":"17.5","Brain RNA - pons [nTPM]":"16.9","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"27.9","Brain RNA - white matter [nTPM]":"33.5","Single Cell Type RNA - Adipocytes [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"102.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"54.4","Single Cell Type RNA - dendritic cells [nTPM]":"25.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"10.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.0","Single Cell Type RNA - Fibroblasts [nTPM]":"19.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"19.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"81.3","Single Cell Type RNA - T-cells [nTPM]":"5.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MARS1","Gene synonym":["CMT2U","MARS","MetRS","SPG70"],"Ensembl":"ENSG00000166986","Gene description":"Methionyl-tRNA synthetase 1","Uniprot":["P56192"],"Chromosome":"12","Position":"57475445-57517569","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","RNA-binding","tRNA-binding"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"11.9","Cytotrophoblasts":"29.5","Extravillous trophoblasts":"22.0","Hofbauer cells":"19.3","Syncytiotrophoblasts":"38.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"738.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004125","CAB017097"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB017097":null,"HPA004125":"AB_1079312"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.55e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"35.9","Tissue RNA - adrenal gland [nTPM]":"47.2","Tissue RNA - amygdala [nTPM]":"63.1","Tissue RNA - appendix [nTPM]":"35.9","Tissue RNA - basal ganglia [nTPM]":"65.2","Tissue RNA - bone marrow [nTPM]":"31.6","Tissue RNA - breast [nTPM]":"31.5","Tissue RNA - cerebellum [nTPM]":"62.0","Tissue RNA - cerebral cortex [nTPM]":"83.6","Tissue RNA - cervix [nTPM]":"30.8","Tissue RNA - choroid plexus [nTPM]":"61.6","Tissue RNA - colon [nTPM]":"47.6","Tissue RNA - duodenum [nTPM]":"21.5","Tissue RNA - endometrium 1 [nTPM]":"40.7","Tissue RNA - epididymis [nTPM]":"39.0","Tissue RNA - esophagus [nTPM]":"54.3","Tissue RNA - fallopian tube [nTPM]":"30.1","Tissue RNA - gallbladder [nTPM]":"19.3","Tissue RNA - heart muscle [nTPM]":"50.5","Tissue RNA - hippocampal formation [nTPM]":"67.5","Tissue RNA - hypothalamus [nTPM]":"67.5","Tissue RNA - kidney [nTPM]":"55.7","Tissue RNA - liver [nTPM]":"60.6","Tissue RNA - lung [nTPM]":"42.7","Tissue RNA - lymph node [nTPM]":"34.5","Tissue RNA - medulla oblongata [nTPM]":"64.2","Tissue RNA - midbrain [nTPM]":"65.5","Tissue RNA - ovary [nTPM]":"24.2","Tissue RNA - pancreas [nTPM]":"64.4","Tissue RNA - parathyroid gland [nTPM]":"40.7","Tissue RNA - pituitary gland [nTPM]":"58.9","Tissue RNA - placenta [nTPM]":"27.3","Tissue RNA - pons [nTPM]":"68.1","Tissue RNA - prostate [nTPM]":"38.7","Tissue RNA - rectum [nTPM]":"29.6","Tissue RNA - retina [nTPM]":"39.6","Tissue RNA - salivary gland [nTPM]":"39.6","Tissue RNA - seminal vesicle [nTPM]":"34.0","Tissue RNA - skeletal muscle [nTPM]":"48.5","Tissue RNA - skin 1 [nTPM]":"33.0","Tissue RNA - small intestine [nTPM]":"37.3","Tissue RNA - smooth muscle [nTPM]":"41.3","Tissue RNA - spinal cord [nTPM]":"63.5","Tissue RNA - spleen [nTPM]":"53.9","Tissue RNA - stomach 1 [nTPM]":"53.2","Tissue RNA - testis [nTPM]":"50.7","Tissue RNA - thalamus [nTPM]":"65.6","Tissue RNA - thymus [nTPM]":"32.6","Tissue RNA - thyroid gland [nTPM]":"40.0","Tissue RNA - tongue [nTPM]":"33.1","Tissue RNA - tonsil [nTPM]":"44.4","Tissue RNA - urinary bladder [nTPM]":"44.8","Tissue RNA - vagina [nTPM]":"33.6","Tissue RNA - white matter [nTPM]":"67.9","Cell RNA - A-431 [nTPM]":"110.6","Cell RNA - A549 [nTPM]":"149.6","Cell RNA - AF22 [nTPM]":"99.7","Cell RNA - AN3-CA [nTPM]":"171.9","Cell RNA - ASC diff [nTPM]":"107.1","Cell RNA - ASC TERT1 [nTPM]":"64.6","Cell RNA - BEWO [nTPM]":"180.2","Cell RNA - BJ [nTPM]":"149.0","Cell RNA - BJ hTERT+ [nTPM]":"178.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"158.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"168.6","Cell RNA - CACO-2 [nTPM]":"162.9","Cell RNA - CAPAN-2 [nTPM]":"119.0","Cell RNA - Daudi [nTPM]":"192.3","Cell RNA - EFO-21 [nTPM]":"97.6","Cell RNA - fHDF\/TERT166 [nTPM]":"187.2","Cell RNA - GAMG [nTPM]":"98.3","Cell RNA - HaCaT [nTPM]":"119.4","Cell RNA - HAP1 [nTPM]":"226.0","Cell RNA - HBEC3-KT [nTPM]":"196.4","Cell RNA - HBF TERT88 [nTPM]":"166.2","Cell RNA - HDLM-2 [nTPM]":"167.4","Cell RNA - HEK 293 [nTPM]":"96.9","Cell RNA - HEL [nTPM]":"136.7","Cell RNA - HeLa [nTPM]":"52.8","Cell RNA - Hep G2 [nTPM]":"89.4","Cell RNA - HHSteC [nTPM]":"238.1","Cell RNA - HL-60 [nTPM]":"207.7","Cell RNA - HMC-1 [nTPM]":"147.5","Cell RNA - HSkMC [nTPM]":"96.2","Cell RNA - hTCEpi [nTPM]":"302.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"181.5","Cell RNA - hTERT-HME1 [nTPM]":"467.5","Cell RNA - hTERT-RPE1 [nTPM]":"76.6","Cell RNA - HUVEC TERT2 [nTPM]":"114.8","Cell RNA - JURKAT [nTPM]":"238.1","Cell RNA - K-562 [nTPM]":"212.9","Cell RNA - Karpas-707 [nTPM]":"400.3","Cell RNA - LHCN-M2 [nTPM]":"112.1","Cell RNA - MCF7 [nTPM]":"150.4","Cell RNA - MOLT-4 [nTPM]":"187.9","Cell RNA - NB-4 [nTPM]":"148.1","Cell RNA - NTERA-2 [nTPM]":"184.8","Cell RNA - OE19 [nTPM]":"173.0","Cell RNA - PC-3 [nTPM]":"162.3","Cell RNA - REH [nTPM]":"155.5","Cell RNA - RH-30 [nTPM]":"738.3","Cell RNA - RPMI-8226 [nTPM]":"200.0","Cell RNA - RPTEC TERT1 [nTPM]":"117.0","Cell RNA - RT4 [nTPM]":"86.4","Cell RNA - SCLC-21H [nTPM]":"131.6","Cell RNA - SH-SY5Y [nTPM]":"134.0","Cell RNA - SiHa [nTPM]":"79.8","Cell RNA - SK-BR-3 [nTPM]":"120.9","Cell RNA - SK-MEL-30 [nTPM]":"215.8","Cell RNA - SuSa [nTPM]":"109.6","Cell RNA - T-47d [nTPM]":"161.0","Cell RNA - THP-1 [nTPM]":"260.7","Cell RNA - TIME [nTPM]":"86.9","Cell RNA - U-138 MG [nTPM]":"57.5","Cell RNA - U-2 OS [nTPM]":"162.8","Cell RNA - U-2197 [nTPM]":"82.8","Cell RNA - U-251 MG [nTPM]":"91.6","Cell RNA - U-266\/70 [nTPM]":"357.5","Cell RNA - U-266\/84 [nTPM]":"395.8","Cell RNA - U-698 [nTPM]":"232.5","Cell RNA - U-87 MG [nTPM]":"139.7","Cell RNA - U-937 [nTPM]":"154.8","Cell RNA - WM-115 [nTPM]":"199.1","Blood RNA - basophil [nTPM]":"29.9","Blood RNA - classical monocyte [nTPM]":"29.8","Blood RNA - eosinophil [nTPM]":"39.3","Blood RNA - gdT-cell [nTPM]":"35.1","Blood RNA - intermediate monocyte [nTPM]":"53.6","Blood RNA - MAIT T-cell [nTPM]":"31.7","Blood RNA - memory B-cell [nTPM]":"24.4","Blood RNA - memory CD4 T-cell [nTPM]":"23.4","Blood RNA - memory CD8 T-cell [nTPM]":"32.0","Blood RNA - myeloid DC [nTPM]":"57.9","Blood RNA - naive B-cell [nTPM]":"14.7","Blood RNA - naive CD4 T-cell [nTPM]":"20.0","Blood RNA - naive CD8 T-cell [nTPM]":"27.4","Blood RNA - neutrophil [nTPM]":"14.5","Blood RNA - NK-cell [nTPM]":"30.0","Blood RNA - non-classical monocyte [nTPM]":"45.6","Blood RNA - plasmacytoid DC [nTPM]":"55.9","Blood RNA - T-reg [nTPM]":"26.3","Blood RNA - total PBMC [nTPM]":"34.2","Brain RNA - amygdala [nTPM]":"63.1","Brain RNA - basal ganglia [nTPM]":"65.2","Brain RNA - cerebellum [nTPM]":"62.0","Brain RNA - cerebral cortex [nTPM]":"83.6","Brain RNA - hippocampal formation [nTPM]":"67.5","Brain RNA - hypothalamus [nTPM]":"67.5","Brain RNA - medulla oblongata [nTPM]":"64.2","Brain RNA - midbrain [nTPM]":"65.5","Brain RNA - pons [nTPM]":"68.1","Brain RNA - spinal cord [nTPM]":"63.5","Brain RNA - thalamus [nTPM]":"65.6","Brain RNA - white matter [nTPM]":"67.9","Single Cell Type RNA - Adipocytes [nTPM]":"5.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.5","Single Cell Type RNA - dendritic cells [nTPM]":"7.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MARVELD2","Gene synonym":["DFNB49","FLJ30532","MRVLDC2","TRIC"],"Ensembl":"ENSG00000152939","Gene description":"MARVEL domain containing 2","Uniprot":["Q8N4S9"],"Chromosome":"5","Position":"69415065-69444330","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"15.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Urothelial cells":"46.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"29.5","CAPAN-2":"24.1","HaCaT":"18.9","RT4":"21.1","SCLC-21H":"26.7","T-47d":"18.3"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"8","RNA mouse brain regional specific nTPM":{"cerebellum":"7.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018119","HPA061726"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA018119":"AB_2669771","HPA061726":"AB_2684595"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.84e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"6.9","Tissue RNA - fallopian tube [nTPM]":"3.9","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"10.7","Tissue RNA - lung [nTPM]":"5.6","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"9.3","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"15.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"10.8","Cell RNA - A549 [nTPM]":"3.5","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"29.5","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"14.1","Cell RNA - CAPAN-2 [nTPM]":"24.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"2.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"18.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"14.0","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"5.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"15.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"9.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"6.3","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"10.0","Cell RNA - RT4 [nTPM]":"21.1","Cell RNA - SCLC-21H [nTPM]":"26.7","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.3","Cell RNA - SK-BR-3 [nTPM]":"2.0","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"4.3","Cell RNA - T-47d [nTPM]":"18.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"3.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"23.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"25.1","Single Cell Type RNA - Early spermatids [nTPM]":"5.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"37.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.0","Single Cell Type RNA - Paneth cells [nTPM]":"29.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.6","Single Cell Type RNA - Urothelial cells [nTPM]":"46.9"},{"Gene":"MATR3","Gene synonym":["KIAA0723","MGC9105","MPD2","VCPDM"],"Ensembl":"ENSG00000015479","Gene description":"Matrin 3","Uniprot":["P43243"],"Chromosome":"5","Position":"139293674-139331677","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["RNA-binding"],"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"155.9","Inhibitory neurons":"160.2","Langerhans cells":"122.3","Oligodendrocyte precursor cells":"117.6","Oligodendrocytes":"162.4","Respiratory ciliated cells":"127.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033552","HPA036564","HPA036565"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB033552":"AB_2281755","HPA036564":"AB_10669907","HPA036565":"AB_10673623"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"112.9","Tissue RNA - adrenal gland [nTPM]":"127.9","Tissue RNA - amygdala [nTPM]":"145.2","Tissue RNA - appendix [nTPM]":"93.6","Tissue RNA - basal ganglia [nTPM]":"156.1","Tissue RNA - bone marrow [nTPM]":"323.5","Tissue RNA - breast [nTPM]":"161.0","Tissue RNA - cerebellum [nTPM]":"172.2","Tissue RNA - cerebral cortex [nTPM]":"224.5","Tissue RNA - cervix [nTPM]":"144.1","Tissue RNA - choroid plexus [nTPM]":"109.6","Tissue RNA - colon [nTPM]":"106.3","Tissue RNA - duodenum [nTPM]":"76.9","Tissue RNA - endometrium 1 [nTPM]":"166.6","Tissue RNA - epididymis [nTPM]":"124.0","Tissue RNA - esophagus [nTPM]":"103.3","Tissue RNA - fallopian tube [nTPM]":"131.1","Tissue RNA - gallbladder [nTPM]":"115.3","Tissue RNA - heart muscle [nTPM]":"111.4","Tissue RNA - hippocampal formation [nTPM]":"158.4","Tissue RNA - hypothalamus [nTPM]":"146.1","Tissue RNA - kidney [nTPM]":"150.1","Tissue RNA - liver [nTPM]":"112.9","Tissue RNA - lung [nTPM]":"115.2","Tissue RNA - lymph node [nTPM]":"157.9","Tissue RNA - medulla oblongata [nTPM]":"126.2","Tissue RNA - midbrain [nTPM]":"132.1","Tissue RNA - ovary [nTPM]":"199.3","Tissue RNA - pancreas [nTPM]":"102.8","Tissue RNA - parathyroid gland [nTPM]":"168.6","Tissue RNA - pituitary gland [nTPM]":"95.1","Tissue RNA - placenta [nTPM]":"122.9","Tissue RNA - pons [nTPM]":"131.4","Tissue RNA - prostate [nTPM]":"130.2","Tissue RNA - rectum [nTPM]":"106.5","Tissue RNA - retina [nTPM]":"223.4","Tissue RNA - salivary gland [nTPM]":"93.5","Tissue RNA - seminal vesicle [nTPM]":"133.2","Tissue RNA - skeletal muscle [nTPM]":"119.6","Tissue RNA - skin 1 [nTPM]":"82.0","Tissue RNA - small intestine [nTPM]":"90.0","Tissue RNA - smooth muscle [nTPM]":"142.4","Tissue RNA - spinal cord [nTPM]":"144.8","Tissue RNA - spleen [nTPM]":"124.5","Tissue RNA - stomach 1 [nTPM]":"89.1","Tissue RNA - testis [nTPM]":"114.9","Tissue RNA - thalamus [nTPM]":"139.3","Tissue RNA - thymus [nTPM]":"221.7","Tissue RNA - thyroid gland [nTPM]":"190.5","Tissue RNA - tongue [nTPM]":"114.0","Tissue RNA - tonsil [nTPM]":"170.2","Tissue RNA - urinary bladder [nTPM]":"133.5","Tissue RNA - vagina [nTPM]":"91.2","Tissue RNA - white matter [nTPM]":"156.3","Cell RNA - A-431 [nTPM]":"209.0","Cell RNA - A549 [nTPM]":"191.1","Cell RNA - AF22 [nTPM]":"559.5","Cell RNA - AN3-CA [nTPM]":"260.7","Cell RNA - ASC diff [nTPM]":"192.4","Cell RNA - ASC TERT1 [nTPM]":"212.5","Cell RNA - BEWO [nTPM]":"283.2","Cell RNA - BJ [nTPM]":"172.2","Cell RNA - BJ hTERT+ [nTPM]":"300.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"300.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"347.5","Cell RNA - CACO-2 [nTPM]":"273.1","Cell RNA - CAPAN-2 [nTPM]":"208.8","Cell RNA - Daudi [nTPM]":"351.2","Cell RNA - EFO-21 [nTPM]":"236.8","Cell RNA - fHDF\/TERT166 [nTPM]":"244.1","Cell RNA - GAMG [nTPM]":"284.8","Cell RNA - HaCaT [nTPM]":"135.8","Cell RNA - HAP1 [nTPM]":"376.8","Cell RNA - HBEC3-KT [nTPM]":"269.6","Cell RNA - HBF TERT88 [nTPM]":"403.0","Cell RNA - HDLM-2 [nTPM]":"278.4","Cell RNA - HEK 293 [nTPM]":"189.1","Cell RNA - HEL [nTPM]":"236.5","Cell RNA - HeLa [nTPM]":"205.0","Cell RNA - Hep G2 [nTPM]":"285.0","Cell RNA - HHSteC [nTPM]":"183.2","Cell RNA - HL-60 [nTPM]":"262.5","Cell RNA - HMC-1 [nTPM]":"174.4","Cell RNA - HSkMC [nTPM]":"222.5","Cell RNA - hTCEpi [nTPM]":"203.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"247.4","Cell RNA - hTERT-HME1 [nTPM]":"226.3","Cell RNA - hTERT-RPE1 [nTPM]":"247.1","Cell RNA - HUVEC TERT2 [nTPM]":"296.1","Cell RNA - JURKAT [nTPM]":"219.4","Cell RNA - K-562 [nTPM]":"216.9","Cell RNA - Karpas-707 [nTPM]":"170.3","Cell RNA - LHCN-M2 [nTPM]":"313.8","Cell RNA - MCF7 [nTPM]":"186.7","Cell RNA - MOLT-4 [nTPM]":"496.0","Cell RNA - NB-4 [nTPM]":"285.8","Cell RNA - NTERA-2 [nTPM]":"303.6","Cell RNA - OE19 [nTPM]":"205.2","Cell RNA - PC-3 [nTPM]":"182.6","Cell RNA - REH [nTPM]":"304.7","Cell RNA - RH-30 [nTPM]":"416.4","Cell RNA - RPMI-8226 [nTPM]":"217.8","Cell RNA - RPTEC TERT1 [nTPM]":"278.0","Cell RNA - RT4 [nTPM]":"316.5","Cell RNA - SCLC-21H [nTPM]":"279.5","Cell RNA - SH-SY5Y [nTPM]":"348.7","Cell RNA - SiHa [nTPM]":"248.3","Cell RNA - SK-BR-3 [nTPM]":"176.7","Cell RNA - SK-MEL-30 [nTPM]":"264.6","Cell RNA - SuSa [nTPM]":"426.3","Cell RNA - T-47d [nTPM]":"194.4","Cell RNA - THP-1 [nTPM]":"254.5","Cell RNA - TIME [nTPM]":"192.2","Cell RNA - U-138 MG [nTPM]":"272.0","Cell RNA - U-2 OS [nTPM]":"177.7","Cell RNA - U-2197 [nTPM]":"180.6","Cell RNA - U-251 MG [nTPM]":"246.3","Cell RNA - U-266\/70 [nTPM]":"171.0","Cell RNA - U-266\/84 [nTPM]":"300.4","Cell RNA - U-698 [nTPM]":"423.0","Cell RNA - U-87 MG [nTPM]":"189.8","Cell RNA - U-937 [nTPM]":"226.5","Cell RNA - WM-115 [nTPM]":"268.0","Blood RNA - basophil [nTPM]":"187.0","Blood RNA - classical monocyte [nTPM]":"71.2","Blood RNA - eosinophil [nTPM]":"116.3","Blood RNA - gdT-cell [nTPM]":"109.6","Blood RNA - intermediate monocyte [nTPM]":"82.2","Blood RNA - MAIT T-cell [nTPM]":"134.8","Blood RNA - memory B-cell [nTPM]":"116.3","Blood RNA - memory CD4 T-cell [nTPM]":"114.3","Blood RNA - memory CD8 T-cell [nTPM]":"124.6","Blood RNA - myeloid DC [nTPM]":"92.6","Blood RNA - naive B-cell [nTPM]":"97.7","Blood RNA - naive CD4 T-cell [nTPM]":"124.4","Blood RNA - naive CD8 T-cell [nTPM]":"116.5","Blood RNA - neutrophil [nTPM]":"34.7","Blood RNA - NK-cell [nTPM]":"150.9","Blood RNA - non-classical monocyte [nTPM]":"106.7","Blood RNA - plasmacytoid DC [nTPM]":"50.7","Blood RNA - T-reg [nTPM]":"136.1","Blood RNA - total PBMC [nTPM]":"159.8","Brain RNA - amygdala [nTPM]":"145.2","Brain RNA - basal ganglia [nTPM]":"156.1","Brain RNA - cerebellum [nTPM]":"172.2","Brain RNA - cerebral cortex [nTPM]":"224.5","Brain RNA - hippocampal formation [nTPM]":"158.4","Brain RNA - hypothalamus [nTPM]":"146.1","Brain RNA - medulla oblongata [nTPM]":"126.2","Brain RNA - midbrain [nTPM]":"132.1","Brain RNA - pons [nTPM]":"131.4","Brain RNA - spinal cord [nTPM]":"144.8","Brain RNA - thalamus [nTPM]":"139.3","Brain RNA - white matter [nTPM]":"156.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"50.2","Single Cell Type RNA - Astrocytes [nTPM]":"83.6","Single Cell Type RNA - B-cells [nTPM]":"17.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"114.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"99.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"1.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"92.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"13.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"83.5","Single Cell Type RNA - Erythroid cells [nTPM]":"15.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"155.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"17.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"100.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"160.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.3","Single Cell Type RNA - Ionocytes [nTPM]":"87.5","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"122.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"4.7","Single Cell Type RNA - Melanocytes [nTPM]":"103.2","Single Cell Type RNA - Microglial cells [nTPM]":"60.9","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"117.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"162.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"12.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"7.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"127.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"111.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"21.8","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"MATR3","Gene synonym":[],"Ensembl":"ENSG00000280987","Gene description":"Matrin 3","Uniprot":[],"Chromosome":"5","Position":"139273752-139331671","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036564","HPA036565"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA036564":"AB_10669907","HPA036565":"AB_10673623"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.5","Tissue RNA - adrenal gland [nTPM]":"13.5","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"24.4","Tissue RNA - basal ganglia [nTPM]":"14.6","Tissue RNA - bone marrow [nTPM]":"25.1","Tissue RNA - breast [nTPM]":"31.1","Tissue RNA - cerebellum [nTPM]":"9.9","Tissue RNA - cerebral cortex [nTPM]":"24.5","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"22.4","Tissue RNA - duodenum [nTPM]":"16.2","Tissue RNA - endometrium 1 [nTPM]":"15.3","Tissue RNA - epididymis [nTPM]":"34.0","Tissue RNA - esophagus [nTPM]":"17.8","Tissue RNA - fallopian tube [nTPM]":"19.2","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"30.6","Tissue RNA - hippocampal formation [nTPM]":"15.4","Tissue RNA - hypothalamus [nTPM]":"12.9","Tissue RNA - kidney [nTPM]":"10.2","Tissue RNA - liver [nTPM]":"9.7","Tissue RNA - lung [nTPM]":"8.4","Tissue RNA - lymph node [nTPM]":"36.1","Tissue RNA - medulla oblongata [nTPM]":"18.4","Tissue RNA - midbrain [nTPM]":"10.9","Tissue RNA - ovary [nTPM]":"14.3","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"8.3","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"18.8","Tissue RNA - prostate [nTPM]":"15.5","Tissue RNA - rectum [nTPM]":"29.3","Tissue RNA - retina [nTPM]":"11.8","Tissue RNA - salivary gland [nTPM]":"26.4","Tissue RNA - seminal vesicle [nTPM]":"8.6","Tissue RNA - skeletal muscle [nTPM]":"41.2","Tissue RNA - skin 1 [nTPM]":"20.4","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"14.8","Tissue RNA - spinal cord [nTPM]":"13.9","Tissue RNA - spleen [nTPM]":"19.9","Tissue RNA - stomach 1 [nTPM]":"17.7","Tissue RNA - testis [nTPM]":"18.6","Tissue RNA - thalamus [nTPM]":"13.5","Tissue RNA - thymus [nTPM]":"17.4","Tissue RNA - thyroid gland [nTPM]":"9.7","Tissue RNA - tongue [nTPM]":"38.4","Tissue RNA - tonsil [nTPM]":"33.7","Tissue RNA - urinary bladder [nTPM]":"14.7","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"21.2","Cell RNA - A-431 [nTPM]":"81.0","Cell RNA - A549 [nTPM]":"58.9","Cell RNA - AF22 [nTPM]":"30.2","Cell RNA - AN3-CA [nTPM]":"162.9","Cell RNA - ASC diff [nTPM]":"65.9","Cell RNA - ASC TERT1 [nTPM]":"79.7","Cell RNA - BEWO [nTPM]":"58.6","Cell RNA - BJ [nTPM]":"42.8","Cell RNA - BJ hTERT+ [nTPM]":"36.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"69.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"87.0","Cell RNA - CACO-2 [nTPM]":"101.7","Cell RNA - CAPAN-2 [nTPM]":"71.7","Cell RNA - Daudi [nTPM]":"284.8","Cell RNA - EFO-21 [nTPM]":"60.7","Cell RNA - fHDF\/TERT166 [nTPM]":"61.2","Cell RNA - GAMG [nTPM]":"45.0","Cell RNA - HaCaT [nTPM]":"91.2","Cell RNA - HAP1 [nTPM]":"257.9","Cell RNA - HBEC3-KT [nTPM]":"136.3","Cell RNA - HBF TERT88 [nTPM]":"120.5","Cell RNA - HDLM-2 [nTPM]":"48.7","Cell RNA - HEK 293 [nTPM]":"125.6","Cell RNA - HEL [nTPM]":"190.2","Cell RNA - HeLa [nTPM]":"100.3","Cell RNA - Hep G2 [nTPM]":"89.8","Cell RNA - HHSteC [nTPM]":"57.6","Cell RNA - HL-60 [nTPM]":"176.9","Cell RNA - HMC-1 [nTPM]":"67.9","Cell RNA - HSkMC [nTPM]":"93.7","Cell RNA - hTCEpi [nTPM]":"95.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"79.6","Cell RNA - hTERT-HME1 [nTPM]":"90.7","Cell RNA - hTERT-RPE1 [nTPM]":"38.6","Cell RNA - HUVEC TERT2 [nTPM]":"78.9","Cell RNA - JURKAT [nTPM]":"103.7","Cell RNA - K-562 [nTPM]":"143.2","Cell RNA - Karpas-707 [nTPM]":"50.3","Cell RNA - LHCN-M2 [nTPM]":"74.0","Cell RNA - MCF7 [nTPM]":"31.7","Cell RNA - MOLT-4 [nTPM]":"98.5","Cell RNA - NB-4 [nTPM]":"53.4","Cell RNA - NTERA-2 [nTPM]":"122.7","Cell RNA - OE19 [nTPM]":"35.4","Cell RNA - PC-3 [nTPM]":"38.8","Cell RNA - REH [nTPM]":"199.0","Cell RNA - RH-30 [nTPM]":"92.8","Cell RNA - RPMI-8226 [nTPM]":"125.1","Cell RNA - RPTEC TERT1 [nTPM]":"40.3","Cell RNA - RT4 [nTPM]":"55.7","Cell RNA - SCLC-21H [nTPM]":"92.6","Cell RNA - SH-SY5Y [nTPM]":"56.5","Cell RNA - SiHa [nTPM]":"49.4","Cell RNA - SK-BR-3 [nTPM]":"60.7","Cell RNA - SK-MEL-30 [nTPM]":"113.6","Cell RNA - SuSa [nTPM]":"77.3","Cell RNA - T-47d [nTPM]":"57.0","Cell RNA - THP-1 [nTPM]":"71.1","Cell RNA - TIME [nTPM]":"56.3","Cell RNA - U-138 MG [nTPM]":"52.8","Cell RNA - U-2 OS [nTPM]":"78.5","Cell RNA - U-2197 [nTPM]":"43.7","Cell RNA - U-251 MG [nTPM]":"63.7","Cell RNA - U-266\/70 [nTPM]":"23.3","Cell RNA - U-266\/84 [nTPM]":"33.6","Cell RNA - U-698 [nTPM]":"153.2","Cell RNA - U-87 MG [nTPM]":"45.8","Cell RNA - U-937 [nTPM]":"148.1","Cell RNA - WM-115 [nTPM]":"61.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"3.2","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"14.6","Brain RNA - cerebellum [nTPM]":"9.9","Brain RNA - cerebral cortex [nTPM]":"24.5","Brain RNA - hippocampal formation [nTPM]":"15.4","Brain RNA - hypothalamus [nTPM]":"12.9","Brain RNA - medulla oblongata [nTPM]":"18.4","Brain RNA - midbrain [nTPM]":"10.9","Brain RNA - pons [nTPM]":"18.8","Brain RNA - spinal cord [nTPM]":"13.9","Brain RNA - thalamus [nTPM]":"13.5","Brain RNA - white matter [nTPM]":"21.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MCM2","Gene synonym":["BM28","CCNL1","cdc19","CDCL1","D3S3194","DFNA70","KIAA0030"],"Ensembl":"ENSG00000073111","Gene description":"Minichromosome maintenance complex component 2","Uniprot":["P49736"],"Chromosome":"3","Position":"127598410-127622436","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA replication"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"67.7","lymphoid tissue":"37.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"63.3","Erythroid cells":"65.6","Extravillous trophoblasts":"28.8","Spermatogonia":"25.9","Syncytiotrophoblasts":"33.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000303","HPA031450","HPA031495","HPA031496"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000303":"AB_322519","HPA031450":null,"HPA031495":"AB_2673904","HPA031496":"AB_2673905"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.66e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.51e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"3.4","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"16.4","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"67.7","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"9.2","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"5.0","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"6.4","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"26.8","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"3.0","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"10.2","Tissue RNA - retina [nTPM]":"3.5","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"9.4","Tissue RNA - skin 1 [nTPM]":"10.6","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"9.6","Tissue RNA - stomach 1 [nTPM]":"5.7","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"37.6","Tissue RNA - thyroid gland [nTPM]":"4.8","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"26.0","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"133.6","Cell RNA - A549 [nTPM]":"110.3","Cell RNA - AF22 [nTPM]":"122.4","Cell RNA - AN3-CA [nTPM]":"102.1","Cell RNA - ASC diff [nTPM]":"7.0","Cell RNA - ASC TERT1 [nTPM]":"14.4","Cell RNA - BEWO [nTPM]":"110.5","Cell RNA - BJ [nTPM]":"65.2","Cell RNA - BJ hTERT+ [nTPM]":"42.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"129.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"146.9","Cell RNA - CACO-2 [nTPM]":"177.7","Cell RNA - CAPAN-2 [nTPM]":"84.7","Cell RNA - Daudi [nTPM]":"136.0","Cell RNA - EFO-21 [nTPM]":"65.2","Cell RNA - fHDF\/TERT166 [nTPM]":"32.3","Cell RNA - GAMG [nTPM]":"113.6","Cell RNA - HaCaT [nTPM]":"105.6","Cell RNA - HAP1 [nTPM]":"204.8","Cell RNA - HBEC3-KT [nTPM]":"76.1","Cell RNA - HBF TERT88 [nTPM]":"79.1","Cell RNA - HDLM-2 [nTPM]":"127.2","Cell RNA - HEK 293 [nTPM]":"127.1","Cell RNA - HEL [nTPM]":"227.4","Cell RNA - HeLa [nTPM]":"134.8","Cell RNA - Hep G2 [nTPM]":"131.1","Cell RNA - HHSteC [nTPM]":"4.4","Cell RNA - HL-60 [nTPM]":"214.3","Cell RNA - HMC-1 [nTPM]":"102.4","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"8.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"86.1","Cell RNA - hTERT-HME1 [nTPM]":"13.1","Cell RNA - hTERT-RPE1 [nTPM]":"15.3","Cell RNA - HUVEC TERT2 [nTPM]":"40.6","Cell RNA - JURKAT [nTPM]":"160.7","Cell RNA - K-562 [nTPM]":"116.0","Cell RNA - Karpas-707 [nTPM]":"123.7","Cell RNA - LHCN-M2 [nTPM]":"47.4","Cell RNA - MCF7 [nTPM]":"169.0","Cell RNA - MOLT-4 [nTPM]":"229.0","Cell RNA - NB-4 [nTPM]":"156.2","Cell RNA - NTERA-2 [nTPM]":"172.5","Cell RNA - OE19 [nTPM]":"108.3","Cell RNA - PC-3 [nTPM]":"90.7","Cell RNA - REH [nTPM]":"242.4","Cell RNA - RH-30 [nTPM]":"165.1","Cell RNA - RPMI-8226 [nTPM]":"203.3","Cell RNA - RPTEC TERT1 [nTPM]":"26.9","Cell RNA - RT4 [nTPM]":"97.9","Cell RNA - SCLC-21H [nTPM]":"143.0","Cell RNA - SH-SY5Y [nTPM]":"106.8","Cell RNA - SiHa [nTPM]":"175.8","Cell RNA - SK-BR-3 [nTPM]":"48.9","Cell RNA - SK-MEL-30 [nTPM]":"16.7","Cell RNA - SuSa [nTPM]":"45.7","Cell RNA - T-47d [nTPM]":"111.9","Cell RNA - THP-1 [nTPM]":"165.3","Cell RNA - TIME [nTPM]":"20.3","Cell RNA - U-138 MG [nTPM]":"104.2","Cell RNA - U-2 OS [nTPM]":"87.9","Cell RNA - U-2197 [nTPM]":"128.4","Cell RNA - U-251 MG [nTPM]":"91.7","Cell RNA - U-266\/70 [nTPM]":"127.1","Cell RNA - U-266\/84 [nTPM]":"163.5","Cell RNA - U-698 [nTPM]":"362.6","Cell RNA - U-87 MG [nTPM]":"73.2","Cell RNA - U-937 [nTPM]":"159.7","Cell RNA - WM-115 [nTPM]":"41.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"9.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.4","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"8.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.7","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"6.5","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"3.7","Blood RNA - T-reg [nTPM]":"11.2","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"8.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.3","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"65.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.8","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"18.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"9.2","Single Cell Type RNA - Muller glia cells [nTPM]":"2.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"20.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.1","Single Cell Type RNA - Spermatogonia [nTPM]":"25.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.5","Single Cell Type RNA - T-cells [nTPM]":"6.3","Single Cell Type RNA - Theca cells [nTPM]":"3.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"MCM3AP","Gene synonym":["GANP","KIAA0572","Map80","SAC3"],"Ensembl":"ENSG00000160294","Gene description":"Minichromosome maintenance complex component 3 associated protein","Uniprot":["O60318"],"Chromosome":"21","Position":"46235133-46286297","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Immunity","mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Mental retardation","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021527","HPA032103"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nuclear membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA021527":"AB_1853626","HPA032103":"AB_2674152"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.8","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"10.0","Tissue RNA - appendix [nTPM]":"20.3","Tissue RNA - basal ganglia [nTPM]":"11.5","Tissue RNA - bone marrow [nTPM]":"19.7","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"14.7","Tissue RNA - choroid plexus [nTPM]":"17.0","Tissue RNA - colon [nTPM]":"15.1","Tissue RNA - duodenum [nTPM]":"14.0","Tissue RNA - endometrium 1 [nTPM]":"16.5","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"15.1","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"7.8","Tissue RNA - kidney [nTPM]":"13.0","Tissue RNA - liver [nTPM]":"9.7","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"21.0","Tissue RNA - medulla oblongata [nTPM]":"10.8","Tissue RNA - midbrain [nTPM]":"10.4","Tissue RNA - ovary [nTPM]":"17.6","Tissue RNA - pancreas [nTPM]":"15.4","Tissue RNA - parathyroid gland [nTPM]":"16.9","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"16.3","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"14.2","Tissue RNA - rectum [nTPM]":"15.0","Tissue RNA - retina [nTPM]":"12.8","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"13.4","Tissue RNA - skeletal muscle [nTPM]":"41.3","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"16.1","Tissue RNA - smooth muscle [nTPM]":"17.1","Tissue RNA - spinal cord [nTPM]":"9.4","Tissue RNA - spleen [nTPM]":"19.6","Tissue RNA - stomach 1 [nTPM]":"15.4","Tissue RNA - testis [nTPM]":"14.1","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"21.7","Tissue RNA - thyroid gland [nTPM]":"16.0","Tissue RNA - tongue [nTPM]":"28.7","Tissue RNA - tonsil [nTPM]":"21.5","Tissue RNA - urinary bladder [nTPM]":"13.6","Tissue RNA - vagina [nTPM]":"11.2","Tissue RNA - white matter [nTPM]":"14.6","Cell RNA - A-431 [nTPM]":"38.0","Cell RNA - A549 [nTPM]":"36.3","Cell RNA - AF22 [nTPM]":"41.8","Cell RNA - AN3-CA [nTPM]":"45.5","Cell RNA - ASC diff [nTPM]":"33.1","Cell RNA - ASC TERT1 [nTPM]":"41.4","Cell RNA - BEWO [nTPM]":"38.0","Cell RNA - BJ [nTPM]":"40.8","Cell RNA - BJ hTERT+ [nTPM]":"48.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"37.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.2","Cell RNA - CACO-2 [nTPM]":"33.1","Cell RNA - CAPAN-2 [nTPM]":"21.9","Cell RNA - Daudi [nTPM]":"53.6","Cell RNA - EFO-21 [nTPM]":"32.9","Cell RNA - fHDF\/TERT166 [nTPM]":"43.2","Cell RNA - GAMG [nTPM]":"40.3","Cell RNA - HaCaT [nTPM]":"21.9","Cell RNA - HAP1 [nTPM]":"55.9","Cell RNA - HBEC3-KT [nTPM]":"34.0","Cell RNA - HBF TERT88 [nTPM]":"32.7","Cell RNA - HDLM-2 [nTPM]":"55.7","Cell RNA - HEK 293 [nTPM]":"50.8","Cell RNA - HEL [nTPM]":"87.9","Cell RNA - HeLa [nTPM]":"35.0","Cell RNA - Hep G2 [nTPM]":"25.9","Cell RNA - HHSteC [nTPM]":"29.6","Cell RNA - HL-60 [nTPM]":"40.6","Cell RNA - HMC-1 [nTPM]":"47.7","Cell RNA - HSkMC [nTPM]":"31.7","Cell RNA - hTCEpi [nTPM]":"28.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"51.2","Cell RNA - hTERT-HME1 [nTPM]":"35.2","Cell RNA - hTERT-RPE1 [nTPM]":"25.4","Cell RNA - HUVEC TERT2 [nTPM]":"40.7","Cell RNA - JURKAT [nTPM]":"31.7","Cell RNA - K-562 [nTPM]":"107.3","Cell RNA - Karpas-707 [nTPM]":"39.6","Cell RNA - LHCN-M2 [nTPM]":"43.3","Cell RNA - MCF7 [nTPM]":"21.1","Cell RNA - MOLT-4 [nTPM]":"43.5","Cell RNA - NB-4 [nTPM]":"26.8","Cell RNA - NTERA-2 [nTPM]":"72.3","Cell RNA - OE19 [nTPM]":"40.0","Cell RNA - PC-3 [nTPM]":"30.2","Cell RNA - REH [nTPM]":"56.3","Cell RNA - RH-30 [nTPM]":"26.6","Cell RNA - RPMI-8226 [nTPM]":"48.9","Cell RNA - RPTEC TERT1 [nTPM]":"17.8","Cell RNA - RT4 [nTPM]":"34.1","Cell RNA - SCLC-21H [nTPM]":"35.2","Cell RNA - SH-SY5Y [nTPM]":"37.6","Cell RNA - SiHa [nTPM]":"52.4","Cell RNA - SK-BR-3 [nTPM]":"33.7","Cell RNA - SK-MEL-30 [nTPM]":"39.0","Cell RNA - SuSa [nTPM]":"31.5","Cell RNA - T-47d [nTPM]":"46.0","Cell RNA - THP-1 [nTPM]":"41.2","Cell RNA - TIME [nTPM]":"51.6","Cell RNA - U-138 MG [nTPM]":"39.1","Cell RNA - U-2 OS [nTPM]":"29.7","Cell RNA - U-2197 [nTPM]":"33.1","Cell RNA - U-251 MG [nTPM]":"31.0","Cell RNA - U-266\/70 [nTPM]":"71.8","Cell RNA - U-266\/84 [nTPM]":"86.2","Cell RNA - U-698 [nTPM]":"33.0","Cell RNA - U-87 MG [nTPM]":"35.3","Cell RNA - U-937 [nTPM]":"38.0","Cell RNA - WM-115 [nTPM]":"51.8","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"10.0","Brain RNA - basal ganglia [nTPM]":"11.5","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"7.8","Brain RNA - medulla oblongata [nTPM]":"10.8","Brain RNA - midbrain [nTPM]":"10.4","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"9.4","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"14.6","Single Cell Type RNA - Adipocytes [nTPM]":"17.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.9","Single Cell Type RNA - Astrocytes [nTPM]":"28.1","Single Cell Type RNA - B-cells [nTPM]":"21.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"21.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"12.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - dendritic cells [nTPM]":"20.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.7","Single Cell Type RNA - Endothelial cells [nTPM]":"14.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.7","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"20.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"18.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.4","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.7","Single Cell Type RNA - Langerhans cells [nTPM]":"8.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"18.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"24.3","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.9","Single Cell Type RNA - Paneth cells [nTPM]":"8.6","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"21.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"19.7","Single Cell Type RNA - Spermatogonia [nTPM]":"15.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"19.1","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.9","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"MDH1","Gene synonym":[],"Ensembl":"ENSG00000014641","Gene description":"Malate dehydrogenase 1","Uniprot":["P40925"],"Chromosome":"2","Position":"63588609-63607197","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"1349.1","tongue":"1843.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1926.9","Proximal tubular cells":"1428.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027296","CAB047333","HPA054276"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"49000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB047333":null,"HPA027296":"AB_10611118","HPA054276":"AB_2682434"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.13e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.95e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"274.6","Tissue RNA - adrenal gland [nTPM]":"213.6","Tissue RNA - amygdala [nTPM]":"235.9","Tissue RNA - appendix [nTPM]":"86.7","Tissue RNA - basal ganglia [nTPM]":"249.7","Tissue RNA - bone marrow [nTPM]":"79.1","Tissue RNA - breast [nTPM]":"137.9","Tissue RNA - cerebellum [nTPM]":"245.9","Tissue RNA - cerebral cortex [nTPM]":"353.6","Tissue RNA - cervix [nTPM]":"89.6","Tissue RNA - choroid plexus [nTPM]":"230.2","Tissue RNA - colon [nTPM]":"167.7","Tissue RNA - duodenum [nTPM]":"154.7","Tissue RNA - endometrium 1 [nTPM]":"82.0","Tissue RNA - epididymis [nTPM]":"161.3","Tissue RNA - esophagus [nTPM]":"125.3","Tissue RNA - fallopian tube [nTPM]":"114.5","Tissue RNA - gallbladder [nTPM]":"87.2","Tissue RNA - heart muscle [nTPM]":"1349.1","Tissue RNA - hippocampal formation [nTPM]":"253.2","Tissue RNA - hypothalamus [nTPM]":"261.5","Tissue RNA - kidney [nTPM]":"371.6","Tissue RNA - liver [nTPM]":"266.3","Tissue RNA - lung [nTPM]":"89.8","Tissue RNA - lymph node [nTPM]":"131.9","Tissue RNA - medulla oblongata [nTPM]":"248.5","Tissue RNA - midbrain [nTPM]":"218.3","Tissue RNA - ovary [nTPM]":"80.4","Tissue RNA - pancreas [nTPM]":"69.9","Tissue RNA - parathyroid gland [nTPM]":"411.8","Tissue RNA - pituitary gland [nTPM]":"107.2","Tissue RNA - placenta [nTPM]":"92.5","Tissue RNA - pons [nTPM]":"253.3","Tissue RNA - prostate [nTPM]":"125.5","Tissue RNA - rectum [nTPM]":"190.9","Tissue RNA - retina [nTPM]":"240.7","Tissue RNA - salivary gland [nTPM]":"122.0","Tissue RNA - seminal vesicle [nTPM]":"142.0","Tissue RNA - skeletal muscle [nTPM]":"792.5","Tissue RNA - skin 1 [nTPM]":"87.7","Tissue RNA - small intestine [nTPM]":"133.1","Tissue RNA - smooth muscle [nTPM]":"171.5","Tissue RNA - spinal cord [nTPM]":"215.7","Tissue RNA - spleen [nTPM]":"71.6","Tissue RNA - stomach 1 [nTPM]":"192.6","Tissue RNA - testis [nTPM]":"70.5","Tissue RNA - thalamus [nTPM]":"259.1","Tissue RNA - thymus [nTPM]":"170.4","Tissue RNA - thyroid gland [nTPM]":"125.5","Tissue RNA - tongue [nTPM]":"1843.8","Tissue RNA - tonsil [nTPM]":"165.4","Tissue RNA - urinary bladder [nTPM]":"131.5","Tissue RNA - vagina [nTPM]":"62.8","Tissue RNA - white matter [nTPM]":"237.7","Cell RNA - A-431 [nTPM]":"268.2","Cell RNA - A549 [nTPM]":"219.5","Cell RNA - AF22 [nTPM]":"257.8","Cell RNA - AN3-CA [nTPM]":"173.2","Cell RNA - ASC diff [nTPM]":"369.6","Cell RNA - ASC TERT1 [nTPM]":"280.9","Cell RNA - BEWO [nTPM]":"282.3","Cell RNA - BJ [nTPM]":"215.1","Cell RNA - BJ hTERT+ [nTPM]":"295.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"300.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"304.1","Cell RNA - CACO-2 [nTPM]":"252.5","Cell RNA - CAPAN-2 [nTPM]":"215.4","Cell RNA - Daudi [nTPM]":"355.2","Cell RNA - EFO-21 [nTPM]":"112.8","Cell RNA - fHDF\/TERT166 [nTPM]":"264.1","Cell RNA - GAMG [nTPM]":"358.8","Cell RNA - HaCaT [nTPM]":"214.3","Cell RNA - HAP1 [nTPM]":"303.0","Cell RNA - HBEC3-KT [nTPM]":"355.0","Cell RNA - HBF TERT88 [nTPM]":"425.5","Cell RNA - HDLM-2 [nTPM]":"207.6","Cell RNA - HEK 293 [nTPM]":"253.1","Cell RNA - HEL [nTPM]":"337.0","Cell RNA - HeLa [nTPM]":"173.2","Cell RNA - Hep G2 [nTPM]":"376.8","Cell RNA - HHSteC [nTPM]":"202.1","Cell RNA - HL-60 [nTPM]":"384.1","Cell RNA - HMC-1 [nTPM]":"223.9","Cell RNA - HSkMC [nTPM]":"277.7","Cell RNA - hTCEpi [nTPM]":"241.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"271.5","Cell RNA - hTERT-HME1 [nTPM]":"152.7","Cell RNA - hTERT-RPE1 [nTPM]":"236.2","Cell RNA - HUVEC TERT2 [nTPM]":"235.3","Cell RNA - JURKAT [nTPM]":"308.1","Cell RNA - K-562 [nTPM]":"183.7","Cell RNA - Karpas-707 [nTPM]":"217.3","Cell RNA - LHCN-M2 [nTPM]":"395.1","Cell RNA - MCF7 [nTPM]":"157.8","Cell RNA - MOLT-4 [nTPM]":"300.6","Cell RNA - NB-4 [nTPM]":"317.5","Cell RNA - NTERA-2 [nTPM]":"158.0","Cell RNA - OE19 [nTPM]":"376.3","Cell RNA - PC-3 [nTPM]":"266.5","Cell RNA - REH [nTPM]":"235.2","Cell RNA - RH-30 [nTPM]":"349.7","Cell RNA - RPMI-8226 [nTPM]":"310.5","Cell RNA - RPTEC TERT1 [nTPM]":"460.9","Cell RNA - RT4 [nTPM]":"251.0","Cell RNA - SCLC-21H [nTPM]":"249.9","Cell RNA - SH-SY5Y [nTPM]":"153.6","Cell RNA - SiHa [nTPM]":"182.5","Cell RNA - SK-BR-3 [nTPM]":"257.7","Cell RNA - SK-MEL-30 [nTPM]":"384.1","Cell RNA - SuSa [nTPM]":"205.6","Cell RNA - T-47d [nTPM]":"191.9","Cell RNA - THP-1 [nTPM]":"341.9","Cell RNA - TIME [nTPM]":"149.6","Cell RNA - U-138 MG [nTPM]":"220.3","Cell RNA - U-2 OS [nTPM]":"211.9","Cell RNA - U-2197 [nTPM]":"187.1","Cell RNA - U-251 MG [nTPM]":"252.9","Cell RNA - U-266\/70 [nTPM]":"264.6","Cell RNA - U-266\/84 [nTPM]":"264.8","Cell RNA - U-698 [nTPM]":"407.6","Cell RNA - U-87 MG [nTPM]":"266.2","Cell RNA - U-937 [nTPM]":"312.2","Cell RNA - WM-115 [nTPM]":"184.1","Blood RNA - basophil [nTPM]":"271.3","Blood RNA - classical monocyte [nTPM]":"186.3","Blood RNA - eosinophil [nTPM]":"200.2","Blood RNA - gdT-cell [nTPM]":"202.7","Blood RNA - intermediate monocyte [nTPM]":"267.8","Blood RNA - MAIT T-cell [nTPM]":"218.8","Blood RNA - memory B-cell [nTPM]":"258.5","Blood RNA - memory CD4 T-cell [nTPM]":"236.6","Blood RNA - memory CD8 T-cell [nTPM]":"224.6","Blood RNA - myeloid DC [nTPM]":"241.0","Blood RNA - naive B-cell [nTPM]":"258.5","Blood RNA - naive CD4 T-cell [nTPM]":"230.3","Blood RNA - naive CD8 T-cell [nTPM]":"221.6","Blood RNA - neutrophil [nTPM]":"28.1","Blood RNA - NK-cell [nTPM]":"214.6","Blood RNA - non-classical monocyte [nTPM]":"253.4","Blood RNA - plasmacytoid DC [nTPM]":"184.3","Blood RNA - T-reg [nTPM]":"320.9","Blood RNA - total PBMC [nTPM]":"321.2","Brain RNA - amygdala [nTPM]":"235.9","Brain RNA - basal ganglia [nTPM]":"249.7","Brain RNA - cerebellum [nTPM]":"245.9","Brain RNA - cerebral cortex [nTPM]":"353.6","Brain RNA - hippocampal formation [nTPM]":"253.2","Brain RNA - hypothalamus [nTPM]":"261.5","Brain RNA - medulla oblongata [nTPM]":"248.5","Brain RNA - midbrain [nTPM]":"218.3","Brain RNA - pons [nTPM]":"253.3","Brain RNA - spinal cord [nTPM]":"215.7","Brain RNA - thalamus [nTPM]":"259.1","Brain RNA - white matter [nTPM]":"237.7","Single Cell Type RNA - Adipocytes [nTPM]":"44.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.3","Single Cell Type RNA - Astrocytes [nTPM]":"54.9","Single Cell Type RNA - B-cells [nTPM]":"78.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"81.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"109.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"562.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"50.7","Single Cell Type RNA - Bipolar cells [nTPM]":"165.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"81.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"86.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1926.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"95.8","Single Cell Type RNA - Club cells [nTPM]":"227.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"134.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"248.7","Single Cell Type RNA - dendritic cells [nTPM]":"78.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"128.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"630.0","Single Cell Type RNA - Ductal cells [nTPM]":"186.2","Single Cell Type RNA - Early spermatids [nTPM]":"12.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"116.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"72.6","Single Cell Type RNA - Endothelial cells [nTPM]":"61.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"62.8","Single Cell Type RNA - Erythroid cells [nTPM]":"62.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"120.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"108.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"257.0","Single Cell Type RNA - Fibroblasts [nTPM]":"134.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"112.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"68.8","Single Cell Type RNA - granulocytes [nTPM]":"80.5","Single Cell Type RNA - Granulosa cells [nTPM]":"95.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.0","Single Cell Type RNA - Hepatocytes [nTPM]":"153.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"397.0","Single Cell Type RNA - Horizontal cells [nTPM]":"122.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"130.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"115.9","Single Cell Type RNA - Ionocytes [nTPM]":"380.5","Single Cell Type RNA - Kupffer cells [nTPM]":"85.2","Single Cell Type RNA - Langerhans cells [nTPM]":"65.8","Single Cell Type RNA - Late spermatids [nTPM]":"15.1","Single Cell Type RNA - Leydig cells [nTPM]":"100.0","Single Cell Type RNA - Macrophages [nTPM]":"98.4","Single Cell Type RNA - Melanocytes [nTPM]":"177.9","Single Cell Type RNA - Microglial cells [nTPM]":"43.1","Single Cell Type RNA - monocytes [nTPM]":"155.0","Single Cell Type RNA - Muller glia cells [nTPM]":"136.3","Single Cell Type RNA - NK-cells [nTPM]":"73.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"51.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"58.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"91.3","Single Cell Type RNA - Paneth cells [nTPM]":"99.8","Single Cell Type RNA - Peritubular cells [nTPM]":"109.1","Single Cell Type RNA - Plasma cells [nTPM]":"82.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"48.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"177.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1428.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"224.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"164.1","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"68.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"167.8","Single Cell Type RNA - Spermatocytes [nTPM]":"58.0","Single Cell Type RNA - Spermatogonia [nTPM]":"65.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"82.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"149.5","Single Cell Type RNA - T-cells [nTPM]":"84.3","Single Cell Type RNA - Theca cells [nTPM]":"137.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"167.8","Single Cell Type RNA - Urothelial cells [nTPM]":"102.6"},{"Gene":"MDH2","Gene synonym":[],"Ensembl":"ENSG00000146701","Gene description":"Malate dehydrogenase 2","Uniprot":["P40926"],"Chromosome":"7","Position":"76048051-76067508","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"697.1","tongue":"601.9"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019714","HPA019716","HPA019848","HPA026720"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA019714":"AB_1853678","HPA019716":"AB_1853680","HPA019848":"AB_1853683","HPA026720":"AB_1853685"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Tissue RNA - adipose tissue [nTPM]":"76.9","Tissue RNA - adrenal gland [nTPM]":"163.4","Tissue RNA - amygdala [nTPM]":"68.0","Tissue RNA - appendix [nTPM]":"51.4","Tissue RNA - basal ganglia [nTPM]":"73.6","Tissue RNA - bone marrow [nTPM]":"71.9","Tissue RNA - breast [nTPM]":"73.9","Tissue RNA - cerebellum [nTPM]":"62.1","Tissue RNA - cerebral cortex [nTPM]":"83.9","Tissue RNA - cervix [nTPM]":"67.4","Tissue RNA - choroid plexus [nTPM]":"81.3","Tissue RNA - colon [nTPM]":"118.7","Tissue RNA - duodenum [nTPM]":"112.7","Tissue RNA - endometrium 1 [nTPM]":"69.2","Tissue RNA - epididymis [nTPM]":"34.7","Tissue RNA - esophagus [nTPM]":"144.9","Tissue RNA - fallopian tube [nTPM]":"66.8","Tissue RNA - gallbladder [nTPM]":"38.0","Tissue RNA - heart muscle [nTPM]":"367.5","Tissue RNA - hippocampal formation [nTPM]":"73.5","Tissue RNA - hypothalamus [nTPM]":"69.9","Tissue RNA - kidney [nTPM]":"121.7","Tissue RNA - liver [nTPM]":"215.5","Tissue RNA - lung [nTPM]":"60.7","Tissue RNA - lymph node [nTPM]":"62.4","Tissue RNA - medulla oblongata [nTPM]":"66.7","Tissue RNA - midbrain [nTPM]":"61.4","Tissue RNA - ovary [nTPM]":"64.1","Tissue RNA - pancreas [nTPM]":"118.3","Tissue RNA - parathyroid gland [nTPM]":"90.5","Tissue RNA - pituitary gland [nTPM]":"70.7","Tissue RNA - placenta [nTPM]":"45.2","Tissue RNA - pons [nTPM]":"67.0","Tissue RNA - prostate [nTPM]":"67.3","Tissue RNA - rectum [nTPM]":"80.3","Tissue RNA - retina [nTPM]":"40.2","Tissue RNA - salivary gland [nTPM]":"98.8","Tissue RNA - seminal vesicle [nTPM]":"56.8","Tissue RNA - skeletal muscle [nTPM]":"697.1","Tissue RNA - skin 1 [nTPM]":"119.5","Tissue RNA - small intestine [nTPM]":"94.4","Tissue RNA - smooth muscle [nTPM]":"60.0","Tissue RNA - spinal cord [nTPM]":"56.3","Tissue RNA - spleen [nTPM]":"75.6","Tissue RNA - stomach 1 [nTPM]":"103.2","Tissue RNA - testis [nTPM]":"60.2","Tissue RNA - thalamus [nTPM]":"64.1","Tissue RNA - thymus [nTPM]":"60.4","Tissue RNA - thyroid gland [nTPM]":"62.3","Tissue RNA - tongue [nTPM]":"601.9","Tissue RNA - tonsil [nTPM]":"66.2","Tissue RNA - urinary bladder [nTPM]":"85.6","Tissue RNA - vagina [nTPM]":"82.4","Tissue RNA - white matter [nTPM]":"66.6","Cell RNA - A-431 [nTPM]":"176.5","Cell RNA - A549 [nTPM]":"278.4","Cell RNA - AF22 [nTPM]":"99.2","Cell RNA - AN3-CA [nTPM]":"250.7","Cell RNA - ASC diff [nTPM]":"110.3","Cell RNA - ASC TERT1 [nTPM]":"121.2","Cell RNA - BEWO [nTPM]":"172.0","Cell RNA - BJ [nTPM]":"113.9","Cell RNA - BJ hTERT+ [nTPM]":"145.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"159.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"143.2","Cell RNA - CACO-2 [nTPM]":"246.2","Cell RNA - CAPAN-2 [nTPM]":"204.7","Cell RNA - Daudi [nTPM]":"261.3","Cell RNA - EFO-21 [nTPM]":"51.1","Cell RNA - fHDF\/TERT166 [nTPM]":"151.1","Cell RNA - GAMG [nTPM]":"172.6","Cell RNA - HaCaT [nTPM]":"174.4","Cell RNA - HAP1 [nTPM]":"256.3","Cell RNA - HBEC3-KT [nTPM]":"170.0","Cell RNA - HBF TERT88 [nTPM]":"112.7","Cell RNA - HDLM-2 [nTPM]":"192.1","Cell RNA - HEK 293 [nTPM]":"368.3","Cell RNA - HEL [nTPM]":"144.6","Cell RNA - HeLa [nTPM]":"138.7","Cell RNA - Hep G2 [nTPM]":"229.9","Cell RNA - HHSteC [nTPM]":"135.2","Cell RNA - HL-60 [nTPM]":"229.3","Cell RNA - HMC-1 [nTPM]":"144.6","Cell RNA - HSkMC [nTPM]":"153.7","Cell RNA - hTCEpi [nTPM]":"149.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"155.2","Cell RNA - hTERT-HME1 [nTPM]":"229.3","Cell RNA - hTERT-RPE1 [nTPM]":"124.9","Cell RNA - HUVEC TERT2 [nTPM]":"150.9","Cell RNA - JURKAT [nTPM]":"160.5","Cell RNA - K-562 [nTPM]":"466.3","Cell RNA - Karpas-707 [nTPM]":"149.4","Cell RNA - LHCN-M2 [nTPM]":"149.7","Cell RNA - MCF7 [nTPM]":"389.6","Cell RNA - MOLT-4 [nTPM]":"206.4","Cell RNA - NB-4 [nTPM]":"402.1","Cell RNA - NTERA-2 [nTPM]":"222.8","Cell RNA - OE19 [nTPM]":"306.6","Cell RNA - PC-3 [nTPM]":"344.3","Cell RNA - REH [nTPM]":"164.3","Cell RNA - RH-30 [nTPM]":"121.7","Cell RNA - RPMI-8226 [nTPM]":"379.9","Cell RNA - RPTEC TERT1 [nTPM]":"149.9","Cell RNA - RT4 [nTPM]":"225.5","Cell RNA - SCLC-21H [nTPM]":"247.4","Cell RNA - SH-SY5Y [nTPM]":"226.9","Cell RNA - SiHa [nTPM]":"114.6","Cell RNA - SK-BR-3 [nTPM]":"567.5","Cell RNA - SK-MEL-30 [nTPM]":"247.0","Cell RNA - SuSa [nTPM]":"124.9","Cell RNA - T-47d [nTPM]":"323.4","Cell RNA - THP-1 [nTPM]":"260.0","Cell RNA - TIME [nTPM]":"117.7","Cell RNA - U-138 MG [nTPM]":"160.0","Cell RNA - U-2 OS [nTPM]":"151.6","Cell RNA - U-2197 [nTPM]":"175.5","Cell RNA - U-251 MG [nTPM]":"232.7","Cell RNA - U-266\/70 [nTPM]":"166.5","Cell RNA - U-266\/84 [nTPM]":"148.1","Cell RNA - U-698 [nTPM]":"290.8","Cell RNA - U-87 MG [nTPM]":"138.6","Cell RNA - U-937 [nTPM]":"289.1","Cell RNA - WM-115 [nTPM]":"249.1","Blood RNA - basophil [nTPM]":"95.4","Blood RNA - classical monocyte [nTPM]":"129.9","Blood RNA - eosinophil [nTPM]":"63.3","Blood RNA - gdT-cell [nTPM]":"102.4","Blood RNA - intermediate monocyte [nTPM]":"148.8","Blood RNA - MAIT T-cell [nTPM]":"107.1","Blood RNA - memory B-cell [nTPM]":"122.2","Blood RNA - memory CD4 T-cell [nTPM]":"113.7","Blood RNA - memory CD8 T-cell [nTPM]":"111.2","Blood RNA - myeloid DC [nTPM]":"176.0","Blood RNA - naive B-cell [nTPM]":"110.2","Blood RNA - naive CD4 T-cell [nTPM]":"109.0","Blood RNA - naive CD8 T-cell [nTPM]":"102.6","Blood RNA - neutrophil [nTPM]":"34.0","Blood RNA - NK-cell [nTPM]":"107.4","Blood RNA - non-classical monocyte [nTPM]":"164.2","Blood RNA - plasmacytoid DC [nTPM]":"157.2","Blood RNA - T-reg [nTPM]":"156.6","Blood RNA - total PBMC [nTPM]":"175.8","Brain RNA - amygdala [nTPM]":"68.0","Brain RNA - basal ganglia [nTPM]":"73.6","Brain RNA - cerebellum [nTPM]":"62.1","Brain RNA - cerebral cortex [nTPM]":"83.9","Brain RNA - hippocampal formation [nTPM]":"73.5","Brain RNA - hypothalamus [nTPM]":"69.9","Brain RNA - medulla oblongata [nTPM]":"66.7","Brain RNA - midbrain [nTPM]":"61.4","Brain RNA - pons [nTPM]":"67.0","Brain RNA - spinal cord [nTPM]":"56.3","Brain RNA - thalamus [nTPM]":"64.1","Brain RNA - white matter [nTPM]":"66.6","Single Cell Type RNA - Adipocytes [nTPM]":"98.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"65.9","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"110.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"135.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"190.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"437.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"118.4","Single Cell Type RNA - Bipolar cells [nTPM]":"68.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"151.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"165.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"486.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"135.8","Single Cell Type RNA - Club cells [nTPM]":"217.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"115.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"328.1","Single Cell Type RNA - dendritic cells [nTPM]":"104.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"242.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"448.0","Single Cell Type RNA - Ductal cells [nTPM]":"269.8","Single Cell Type RNA - Early spermatids [nTPM]":"263.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"108.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"97.9","Single Cell Type RNA - Endothelial cells [nTPM]":"96.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"169.7","Single Cell Type RNA - Erythroid cells [nTPM]":"97.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"333.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"334.0","Single Cell Type RNA - Fibroblasts [nTPM]":"112.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"111.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"104.8","Single Cell Type RNA - granulocytes [nTPM]":"54.5","Single Cell Type RNA - Granulosa cells [nTPM]":"150.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"88.5","Single Cell Type RNA - Hepatocytes [nTPM]":"246.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"248.1","Single Cell Type RNA - Horizontal cells [nTPM]":"72.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"280.6","Single Cell Type RNA - Ionocytes [nTPM]":"288.9","Single Cell Type RNA - Kupffer cells [nTPM]":"132.6","Single Cell Type RNA - Langerhans cells [nTPM]":"113.5","Single Cell Type RNA - Late spermatids [nTPM]":"161.5","Single Cell Type RNA - Leydig cells [nTPM]":"99.4","Single Cell Type RNA - Macrophages [nTPM]":"117.6","Single Cell Type RNA - Melanocytes [nTPM]":"181.5","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"171.4","Single Cell Type RNA - Muller glia cells [nTPM]":"85.7","Single Cell Type RNA - NK-cells [nTPM]":"126.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"255.0","Single Cell Type RNA - Paneth cells [nTPM]":"252.1","Single Cell Type RNA - Peritubular cells [nTPM]":"99.3","Single Cell Type RNA - Plasma cells [nTPM]":"149.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"197.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"433.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"466.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"139.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"67.3","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"114.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"150.9","Single Cell Type RNA - Spermatocytes [nTPM]":"157.8","Single Cell Type RNA - Spermatogonia [nTPM]":"65.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"256.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"166.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"294.8","Single Cell Type RNA - T-cells [nTPM]":"105.4","Single Cell Type RNA - Theca cells [nTPM]":"233.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"372.7","Single Cell Type RNA - Urothelial cells [nTPM]":"234.7"},{"Gene":"MECR","Gene synonym":["CGI-63","ETR1","FASN2B","NRBF1"],"Ensembl":"ENSG00000116353","Gene description":"Mitochondrial trans-2-enoyl-CoA reductase","Uniprot":["Q9BV79"],"Chromosome":"1","Position":"29192657-29230942","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"42.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"82.5","Rod photoreceptor cells":"68.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022018","HPA022030","HPA028740"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA022018":"AB_1853714","HPA022030":"AB_1853716","HPA028740":"AB_10601133"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.81e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.29e-4"},"Tissue RNA - adipose tissue [nTPM]":"14.7","Tissue RNA - adrenal gland [nTPM]":"14.6","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"5.1","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"6.2","Tissue RNA - cervix [nTPM]":"10.2","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"10.3","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"12.9","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"12.5","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"24.8","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"14.1","Tissue RNA - liver [nTPM]":"15.8","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"2.0","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"4.0","Tissue RNA - ovary [nTPM]":"10.0","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"4.5","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"9.9","Tissue RNA - salivary gland [nTPM]":"12.3","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"42.1","Tissue RNA - skin 1 [nTPM]":"15.4","Tissue RNA - small intestine [nTPM]":"7.2","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"8.3","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"5.2","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"4.5","Cell RNA - AF22 [nTPM]":"3.2","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"2.9","Cell RNA - ASC TERT1 [nTPM]":"2.5","Cell RNA - BEWO [nTPM]":"6.8","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.9","Cell RNA - CACO-2 [nTPM]":"2.3","Cell RNA - CAPAN-2 [nTPM]":"5.6","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"5.1","Cell RNA - fHDF\/TERT166 [nTPM]":"3.7","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"5.4","Cell RNA - HBEC3-KT [nTPM]":"6.3","Cell RNA - HBF TERT88 [nTPM]":"4.0","Cell RNA - HDLM-2 [nTPM]":"4.4","Cell RNA - HEK 293 [nTPM]":"6.9","Cell RNA - HEL [nTPM]":"6.4","Cell RNA - HeLa [nTPM]":"3.4","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"4.3","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.1","Cell RNA - hTERT-HME1 [nTPM]":"11.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.8","Cell RNA - HUVEC TERT2 [nTPM]":"3.5","Cell RNA - JURKAT [nTPM]":"6.9","Cell RNA - K-562 [nTPM]":"5.8","Cell RNA - Karpas-707 [nTPM]":"4.2","Cell RNA - LHCN-M2 [nTPM]":"4.7","Cell RNA - MCF7 [nTPM]":"4.5","Cell RNA - MOLT-4 [nTPM]":"3.9","Cell RNA - NB-4 [nTPM]":"2.9","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"5.8","Cell RNA - PC-3 [nTPM]":"4.3","Cell RNA - REH [nTPM]":"3.5","Cell RNA - RH-30 [nTPM]":"4.2","Cell RNA - RPMI-8226 [nTPM]":"9.3","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"2.4","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"4.5","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"7.0","Cell RNA - SuSa [nTPM]":"4.4","Cell RNA - T-47d [nTPM]":"2.3","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"3.8","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"2.9","Cell RNA - U-2197 [nTPM]":"4.1","Cell RNA - U-251 MG [nTPM]":"4.7","Cell RNA - U-266\/70 [nTPM]":"2.7","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"5.0","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"5.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"5.1","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"6.2","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"4.0","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"5.2","Single Cell Type RNA - Adipocytes [nTPM]":"8.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"12.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"21.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"24.3","Single Cell Type RNA - Early spermatids [nTPM]":"40.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"10.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"42.4","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"17.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"19.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.8","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"82.5","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"10.8","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.3","Single Cell Type RNA - Paneth cells [nTPM]":"8.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"68.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"8.5","Single Cell Type RNA - Spermatogonia [nTPM]":"16.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - T-cells [nTPM]":"6.0","Single Cell Type RNA - Theca cells [nTPM]":"25.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.3","Single Cell Type RNA - Urothelial cells [nTPM]":"20.5"},{"Gene":"MERTK","Gene synonym":["c-Eyk","mer","RP38","Tyro12"],"Ensembl":"ENSG00000153208","Gene description":"MER proto-oncogene, tyrosine kinase","Uniprot":["Q12866"],"Chromosome":"2","Position":"111898607-112029561","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant","Proto-oncogene","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"162.6","Kupffer cells":"119.8","Macrophages":"46.5","Microglial cells":"124.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"intermediate monocyte":"8.6","non-classical monocyte":"5.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"50","RNA blood lineage specific nTPM":{"monocytes":"8.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"35.1","Hep G2":"39.9","HUVEC TERT2":"38.4","RT4":"23.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036196","HPA075622"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane","Midbody","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"65000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Endoplasmic reticulum","Midbody","Cytosol"],"Antibody RRID":{"HPA036196":"AB_10670676","HPA075622":"AB_2686759"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.74e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.1","Tissue RNA - adrenal gland [nTPM]":"59.8","Tissue RNA - amygdala [nTPM]":"22.8","Tissue RNA - appendix [nTPM]":"13.5","Tissue RNA - basal ganglia [nTPM]":"28.0","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"15.3","Tissue RNA - cerebellum [nTPM]":"18.0","Tissue RNA - cerebral cortex [nTPM]":"29.3","Tissue RNA - cervix [nTPM]":"12.6","Tissue RNA - choroid plexus [nTPM]":"44.7","Tissue RNA - colon [nTPM]":"10.9","Tissue RNA - duodenum [nTPM]":"12.3","Tissue RNA - endometrium 1 [nTPM]":"11.5","Tissue RNA - epididymis [nTPM]":"26.3","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"22.0","Tissue RNA - hypothalamus [nTPM]":"22.5","Tissue RNA - kidney [nTPM]":"11.4","Tissue RNA - liver [nTPM]":"21.0","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"13.1","Tissue RNA - medulla oblongata [nTPM]":"23.5","Tissue RNA - midbrain [nTPM]":"22.3","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"21.2","Tissue RNA - pituitary gland [nTPM]":"15.5","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"22.4","Tissue RNA - prostate [nTPM]":"14.1","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"16.6","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"16.3","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"14.4","Tissue RNA - spinal cord [nTPM]":"18.4","Tissue RNA - spleen [nTPM]":"30.6","Tissue RNA - stomach 1 [nTPM]":"13.9","Tissue RNA - testis [nTPM]":"17.2","Tissue RNA - thalamus [nTPM]":"30.1","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"10.1","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"13.6","Tissue RNA - vagina [nTPM]":"9.4","Tissue RNA - white matter [nTPM]":"22.0","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"7.6","Cell RNA - AN3-CA [nTPM]":"17.3","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"12.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"35.1","Cell RNA - CAPAN-2 [nTPM]":"2.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"8.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"7.9","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"10.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"5.5","Cell RNA - HEL [nTPM]":"7.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"39.9","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"1.5","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.9","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.0","Cell RNA - HUVEC TERT2 [nTPM]":"38.4","Cell RNA - JURKAT [nTPM]":"1.5","Cell RNA - K-562 [nTPM]":"2.2","Cell RNA - Karpas-707 [nTPM]":"3.5","Cell RNA - LHCN-M2 [nTPM]":"2.9","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"9.1","Cell RNA - NTERA-2 [nTPM]":"4.8","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"6.0","Cell RNA - REH [nTPM]":"2.9","Cell RNA - RH-30 [nTPM]":"2.1","Cell RNA - RPMI-8226 [nTPM]":"3.0","Cell RNA - RPTEC TERT1 [nTPM]":"19.4","Cell RNA - RT4 [nTPM]":"23.4","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"3.2","Cell RNA - SuSa [nTPM]":"2.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"1.0","Cell RNA - U-2 OS [nTPM]":"3.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.1","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"8.6","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"22.8","Brain RNA - basal ganglia [nTPM]":"28.0","Brain RNA - cerebellum [nTPM]":"18.0","Brain RNA - cerebral cortex [nTPM]":"29.3","Brain RNA - hippocampal formation [nTPM]":"22.0","Brain RNA - hypothalamus [nTPM]":"22.5","Brain RNA - medulla oblongata [nTPM]":"23.5","Brain RNA - midbrain [nTPM]":"22.3","Brain RNA - pons [nTPM]":"22.4","Brain RNA - spinal cord [nTPM]":"18.4","Brain RNA - thalamus [nTPM]":"30.1","Brain RNA - white matter [nTPM]":"22.0","Single Cell Type RNA - Adipocytes [nTPM]":"8.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.7","Single Cell Type RNA - Astrocytes [nTPM]":"162.6","Single Cell Type RNA - B-cells [nTPM]":"1.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"6.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"9.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"119.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"46.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"124.6","Single Cell Type RNA - monocytes [nTPM]":"1.5","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"10.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.9","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"3.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"MET","Gene synonym":["DFNB97","HGFR","RCCP2"],"Ensembl":"ENSG00000105976","Gene description":"MET proto-oncogene, receptor tyrosine kinase","Uniprot":["P08581"],"Chromosome":"7","Position":"116672196-116798377","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","FDA approved drug targets","Non-syndromic deafness","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"42.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"103.6","Club cells":"99.8","Glandular and luminal cells":"161.4","Pancreatic endocrine cells":"93.9","Prostatic glandular cells":"149.3","Urothelial cells":"128.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"7.5","hippocampal formation":"6.6","midbrain":"2.5","pons":"4.9","white matter":"7.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"203.8","CAPAN-2":"219.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005282","CAB018577","HPA055607"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":179000000,"Blood concentration - Conc. blood MS [pg\/L]":"100000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005282":"AB_631940","CAB018577":"AB_649068","HPA055607":"AB_2682860"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.75e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.21e-7"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.3","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"7.4","Tissue RNA - breast [nTPM]":"8.9","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"13.1","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"9.7","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"4.7","Tissue RNA - gallbladder [nTPM]":"11.9","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"20.1","Tissue RNA - liver [nTPM]":"42.9","Tissue RNA - lung [nTPM]":"20.3","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"6.6","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"26.4","Tissue RNA - pons [nTPM]":"4.9","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"9.3","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"8.7","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"14.3","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"8.2","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"6.0","Tissue RNA - stomach 1 [nTPM]":"15.4","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"17.6","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"18.4","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"7.8","Cell RNA - A-431 [nTPM]":"203.8","Cell RNA - A549 [nTPM]":"115.3","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"8.6","Cell RNA - ASC TERT1 [nTPM]":"8.7","Cell RNA - BEWO [nTPM]":"7.9","Cell RNA - BJ [nTPM]":"113.7","Cell RNA - BJ hTERT+ [nTPM]":"48.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"60.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.1","Cell RNA - CACO-2 [nTPM]":"25.0","Cell RNA - CAPAN-2 [nTPM]":"219.0","Cell RNA - Daudi [nTPM]":"8.4","Cell RNA - EFO-21 [nTPM]":"179.0","Cell RNA - fHDF\/TERT166 [nTPM]":"72.1","Cell RNA - GAMG [nTPM]":"163.3","Cell RNA - HaCaT [nTPM]":"51.8","Cell RNA - HAP1 [nTPM]":"19.7","Cell RNA - HBEC3-KT [nTPM]":"110.0","Cell RNA - HBF TERT88 [nTPM]":"123.7","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"23.4","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"112.5","Cell RNA - Hep G2 [nTPM]":"21.4","Cell RNA - HHSteC [nTPM]":"1.5","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"11.4","Cell RNA - hTCEpi [nTPM]":"42.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.6","Cell RNA - hTERT-HME1 [nTPM]":"129.1","Cell RNA - hTERT-RPE1 [nTPM]":"109.4","Cell RNA - HUVEC TERT2 [nTPM]":"42.4","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"4.5","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"114.1","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"17.3","Cell RNA - OE19 [nTPM]":"32.9","Cell RNA - PC-3 [nTPM]":"113.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"95.3","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"105.8","Cell RNA - RT4 [nTPM]":"24.0","Cell RNA - SCLC-21H [nTPM]":"16.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"45.4","Cell RNA - SK-BR-3 [nTPM]":"15.4","Cell RNA - SK-MEL-30 [nTPM]":"44.9","Cell RNA - SuSa [nTPM]":"19.8","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"72.3","Cell RNA - U-138 MG [nTPM]":"89.7","Cell RNA - U-2 OS [nTPM]":"30.6","Cell RNA - U-2197 [nTPM]":"46.7","Cell RNA - U-251 MG [nTPM]":"88.9","Cell RNA - U-266\/70 [nTPM]":"2.5","Cell RNA - U-266\/84 [nTPM]":"19.1","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"99.3","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"12.9","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"4.9","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"7.8","Single Cell Type RNA - Adipocytes [nTPM]":"32.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"103.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"70.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"58.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"99.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"76.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"38.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"52.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.6","Single Cell Type RNA - Endothelial cells [nTPM]":"20.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"46.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"161.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"30.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"4.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"93.9","Single Cell Type RNA - Paneth cells [nTPM]":"5.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"149.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.4","Single Cell Type RNA - Urothelial cells [nTPM]":"128.6"},{"Gene":"MFN2","Gene synonym":["CMT2A2","CPRP1","KIAA0214","MARF"],"Ensembl":"ENSG00000116688","Gene description":"Mitofusin 2","Uniprot":["O95140"],"Chromosome":"1","Position":"11980181-12015211","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Autophagy","Unfolded protein response"],"Molecular function":["Hydrolase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"270.4","skeletal muscle":"310.5","tongue":"337.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cardiomyocytes":"336.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030554","CAB079902"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB079902":"AB_2724683","HPA030554":"AB_10603018"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.36e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"34.7","Tissue RNA - adrenal gland [nTPM]":"31.4","Tissue RNA - amygdala [nTPM]":"39.9","Tissue RNA - appendix [nTPM]":"20.9","Tissue RNA - basal ganglia [nTPM]":"42.4","Tissue RNA - bone marrow [nTPM]":"26.7","Tissue RNA - breast [nTPM]":"31.8","Tissue RNA - cerebellum [nTPM]":"39.1","Tissue RNA - cerebral cortex [nTPM]":"41.4","Tissue RNA - cervix [nTPM]":"29.3","Tissue RNA - choroid plexus [nTPM]":"17.4","Tissue RNA - colon [nTPM]":"59.7","Tissue RNA - duodenum [nTPM]":"41.9","Tissue RNA - endometrium 1 [nTPM]":"37.0","Tissue RNA - epididymis [nTPM]":"12.7","Tissue RNA - esophagus [nTPM]":"57.3","Tissue RNA - fallopian tube [nTPM]":"26.2","Tissue RNA - gallbladder [nTPM]":"21.8","Tissue RNA - heart muscle [nTPM]":"270.4","Tissue RNA - hippocampal formation [nTPM]":"34.7","Tissue RNA - hypothalamus [nTPM]":"43.0","Tissue RNA - kidney [nTPM]":"36.5","Tissue RNA - liver [nTPM]":"58.5","Tissue RNA - lung [nTPM]":"31.1","Tissue RNA - lymph node [nTPM]":"19.8","Tissue RNA - medulla oblongata [nTPM]":"41.1","Tissue RNA - midbrain [nTPM]":"44.8","Tissue RNA - ovary [nTPM]":"27.0","Tissue RNA - pancreas [nTPM]":"22.5","Tissue RNA - parathyroid gland [nTPM]":"76.7","Tissue RNA - pituitary gland [nTPM]":"28.7","Tissue RNA - placenta [nTPM]":"27.6","Tissue RNA - pons [nTPM]":"40.6","Tissue RNA - prostate [nTPM]":"36.3","Tissue RNA - rectum [nTPM]":"38.1","Tissue RNA - retina [nTPM]":"35.0","Tissue RNA - salivary gland [nTPM]":"32.2","Tissue RNA - seminal vesicle [nTPM]":"62.3","Tissue RNA - skeletal muscle [nTPM]":"310.5","Tissue RNA - skin 1 [nTPM]":"58.9","Tissue RNA - small intestine [nTPM]":"46.3","Tissue RNA - smooth muscle [nTPM]":"41.2","Tissue RNA - spinal cord [nTPM]":"43.5","Tissue RNA - spleen [nTPM]":"31.5","Tissue RNA - stomach 1 [nTPM]":"44.9","Tissue RNA - testis [nTPM]":"25.4","Tissue RNA - thalamus [nTPM]":"48.8","Tissue RNA - thymus [nTPM]":"26.1","Tissue RNA - thyroid gland [nTPM]":"56.1","Tissue RNA - tongue [nTPM]":"337.6","Tissue RNA - tonsil [nTPM]":"30.4","Tissue RNA - urinary bladder [nTPM]":"51.2","Tissue RNA - vagina [nTPM]":"36.2","Tissue RNA - white matter [nTPM]":"40.5","Cell RNA - A-431 [nTPM]":"93.6","Cell RNA - A549 [nTPM]":"54.0","Cell RNA - AF22 [nTPM]":"52.6","Cell RNA - AN3-CA [nTPM]":"72.7","Cell RNA - ASC diff [nTPM]":"59.7","Cell RNA - ASC TERT1 [nTPM]":"47.2","Cell RNA - BEWO [nTPM]":"58.8","Cell RNA - BJ [nTPM]":"76.0","Cell RNA - BJ hTERT+ [nTPM]":"66.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"96.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"72.6","Cell RNA - CACO-2 [nTPM]":"88.7","Cell RNA - CAPAN-2 [nTPM]":"51.8","Cell RNA - Daudi [nTPM]":"68.8","Cell RNA - EFO-21 [nTPM]":"74.8","Cell RNA - fHDF\/TERT166 [nTPM]":"92.6","Cell RNA - GAMG [nTPM]":"60.6","Cell RNA - HaCaT [nTPM]":"80.5","Cell RNA - HAP1 [nTPM]":"101.7","Cell RNA - HBEC3-KT [nTPM]":"156.1","Cell RNA - HBF TERT88 [nTPM]":"90.6","Cell RNA - HDLM-2 [nTPM]":"60.6","Cell RNA - HEK 293 [nTPM]":"75.4","Cell RNA - HEL [nTPM]":"94.5","Cell RNA - HeLa [nTPM]":"81.8","Cell RNA - Hep G2 [nTPM]":"54.2","Cell RNA - HHSteC [nTPM]":"53.8","Cell RNA - HL-60 [nTPM]":"114.2","Cell RNA - HMC-1 [nTPM]":"51.9","Cell RNA - HSkMC [nTPM]":"57.0","Cell RNA - hTCEpi [nTPM]":"105.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"133.1","Cell RNA - hTERT-HME1 [nTPM]":"124.5","Cell RNA - hTERT-RPE1 [nTPM]":"40.1","Cell RNA - HUVEC TERT2 [nTPM]":"66.2","Cell RNA - JURKAT [nTPM]":"26.4","Cell RNA - K-562 [nTPM]":"106.1","Cell RNA - Karpas-707 [nTPM]":"53.6","Cell RNA - LHCN-M2 [nTPM]":"69.7","Cell RNA - MCF7 [nTPM]":"30.2","Cell RNA - MOLT-4 [nTPM]":"60.2","Cell RNA - NB-4 [nTPM]":"15.2","Cell RNA - NTERA-2 [nTPM]":"39.7","Cell RNA - OE19 [nTPM]":"57.8","Cell RNA - PC-3 [nTPM]":"77.4","Cell RNA - REH [nTPM]":"68.2","Cell RNA - RH-30 [nTPM]":"95.8","Cell RNA - RPMI-8226 [nTPM]":"58.5","Cell RNA - RPTEC TERT1 [nTPM]":"44.9","Cell RNA - RT4 [nTPM]":"61.4","Cell RNA - SCLC-21H [nTPM]":"68.2","Cell RNA - SH-SY5Y [nTPM]":"44.6","Cell RNA - SiHa [nTPM]":"88.4","Cell RNA - SK-BR-3 [nTPM]":"81.0","Cell RNA - SK-MEL-30 [nTPM]":"74.6","Cell RNA - SuSa [nTPM]":"41.4","Cell RNA - T-47d [nTPM]":"43.8","Cell RNA - THP-1 [nTPM]":"49.2","Cell RNA - TIME [nTPM]":"71.2","Cell RNA - U-138 MG [nTPM]":"63.1","Cell RNA - U-2 OS [nTPM]":"58.3","Cell RNA - U-2197 [nTPM]":"88.4","Cell RNA - U-251 MG [nTPM]":"71.2","Cell RNA - U-266\/70 [nTPM]":"59.0","Cell RNA - U-266\/84 [nTPM]":"86.4","Cell RNA - U-698 [nTPM]":"120.7","Cell RNA - U-87 MG [nTPM]":"69.0","Cell RNA - U-937 [nTPM]":"99.6","Cell RNA - WM-115 [nTPM]":"69.8","Blood RNA - basophil [nTPM]":"10.4","Blood RNA - classical monocyte [nTPM]":"11.5","Blood RNA - eosinophil [nTPM]":"7.6","Blood RNA - gdT-cell [nTPM]":"8.9","Blood RNA - intermediate monocyte [nTPM]":"14.0","Blood RNA - MAIT T-cell [nTPM]":"10.2","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"6.7","Blood RNA - memory CD8 T-cell [nTPM]":"7.9","Blood RNA - myeloid DC [nTPM]":"9.7","Blood RNA - naive B-cell [nTPM]":"4.8","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"6.2","Blood RNA - neutrophil [nTPM]":"16.2","Blood RNA - NK-cell [nTPM]":"6.2","Blood RNA - non-classical monocyte [nTPM]":"18.3","Blood RNA - plasmacytoid DC [nTPM]":"4.2","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"15.7","Brain RNA - amygdala [nTPM]":"39.9","Brain RNA - basal ganglia [nTPM]":"42.4","Brain RNA - cerebellum [nTPM]":"39.1","Brain RNA - cerebral cortex [nTPM]":"41.4","Brain RNA - hippocampal formation [nTPM]":"34.7","Brain RNA - hypothalamus [nTPM]":"43.0","Brain RNA - medulla oblongata [nTPM]":"41.1","Brain RNA - midbrain [nTPM]":"44.8","Brain RNA - pons [nTPM]":"40.6","Brain RNA - spinal cord [nTPM]":"43.5","Brain RNA - thalamus [nTPM]":"48.8","Brain RNA - white matter [nTPM]":"40.5","Single Cell Type RNA - Adipocytes [nTPM]":"18.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"10.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"26.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"336.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"14.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"12.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"13.6","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"32.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.5","Single Cell Type RNA - Fibroblasts [nTPM]":"17.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"12.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"46.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.0","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.2","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"23.9","Single Cell Type RNA - Langerhans cells [nTPM]":"9.7","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"19.1","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"17.3","Single Cell Type RNA - Muller glia cells [nTPM]":"14.6","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.5","Single Cell Type RNA - Paneth cells [nTPM]":"16.8","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"10.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.5","Single Cell Type RNA - Spermatocytes [nTPM]":"25.9","Single Cell Type RNA - Spermatogonia [nTPM]":"15.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - T-cells [nTPM]":"10.3","Single Cell Type RNA - Theca cells [nTPM]":"12.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.4","Single Cell Type RNA - Urothelial cells [nTPM]":"16.6"},{"Gene":"MIP","Gene synonym":["AQP0","LIM1","MP26"],"Ensembl":"ENSG00000135517","Gene description":"Major intrinsic protein of lens fiber","Uniprot":["P30301"],"Chromosome":"12","Position":"56449502-56469166","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Transport","Vision"],"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"2.6","Horizontal cells":"1.7","Late spermatids":"2.8","Spermatocytes":"7.3","Spermatogonia":"1.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014940"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014940":"AB_2669122"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"MLC1","Gene synonym":["KIAA0027","LVM","MLC","VL"],"Ensembl":"ENSG00000100427","Gene description":"Modulator of VRAC current 1","Uniprot":["Q15049"],"Chromosome":"22","Position":"50059391-50085426","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"262.7","choroid plexus":"145.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"115.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"69","RNA cancer specific FPKM":{"glioma":"122.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"20.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"228.2","NB-4":"219.8","THP-1":"401.5","U-266\/70":"131.6","U-266\/84":"120.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003040"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA003040":"AB_1079387"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"239.3","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"235.7","Tissue RNA - bone marrow [nTPM]":"36.4","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"212.7","Tissue RNA - cerebral cortex [nTPM]":"261.8","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"145.6","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"225.8","Tissue RNA - hypothalamus [nTPM]":"234.5","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"262.7","Tissue RNA - midbrain [nTPM]":"243.1","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"221.8","Tissue RNA - prostate [nTPM]":"4.8","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"231.9","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"231.5","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"11.9","Tissue RNA - white matter [nTPM]":"217.2","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"2.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"68.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"228.2","Cell RNA - HMC-1 [nTPM]":"68.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"219.8","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"24.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"401.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"131.6","Cell RNA - U-266\/84 [nTPM]":"120.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"35.7","Cell RNA - WM-115 [nTPM]":"2.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"6.8","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"20.2","Blood RNA - non-classical monocyte [nTPM]":"9.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"239.3","Brain RNA - basal ganglia [nTPM]":"235.7","Brain RNA - cerebellum [nTPM]":"212.7","Brain RNA - cerebral cortex [nTPM]":"261.8","Brain RNA - hippocampal formation [nTPM]":"225.8","Brain RNA - hypothalamus [nTPM]":"234.5","Brain RNA - medulla oblongata [nTPM]":"262.7","Brain RNA - midbrain [nTPM]":"243.1","Brain RNA - pons [nTPM]":"221.8","Brain RNA - spinal cord [nTPM]":"231.9","Brain RNA - thalamus [nTPM]":"231.5","Brain RNA - white matter [nTPM]":"217.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"115.6","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"17.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.3","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MME","Gene synonym":["CALLA","CD10","NEP"],"Ensembl":"ENSG00000196549","Gene description":"Membrane metalloendopeptidase","Uniprot":["P08473"],"Chromosome":"3","Position":"155024124-155183704","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Disease variant","FDA approved drug targets","Neurodegeneration","Neuropathy","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"333.5","kidney":"302.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"273.3","Proximal enterocytes":"372.4","Proximal tubular cells":"125.7","Syncytiotrophoblasts":"126.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"17.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"17.3","medulla oblongata":"9.3","pons":"10.9","thalamus":"4.6"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"122","RNA blood cell specific nTPM":{"neutrophil":"139.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"122","RNA blood lineage specific nTPM":{"granulocytes":"139.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"684.4","BJ hTERT+":"1116.9","HSkMC":"651.1"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"28.1"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"32.3","olfactory bulb":"8.5","spinal cord":"15.9"},"Antibody":["CAB000013","HPA052583","HPA056072"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000013":"AB_563478","HPA052583":"AB_2681872","HPA056072":"AB_2683027"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Tissue RNA - adipose tissue [nTPM]":"103.9","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"4.5","Tissue RNA - basal ganglia [nTPM]":"17.3","Tissue RNA - bone marrow [nTPM]":"11.5","Tissue RNA - breast [nTPM]":"38.5","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"22.7","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"333.5","Tissue RNA - endometrium 1 [nTPM]":"13.3","Tissue RNA - epididymis [nTPM]":"22.5","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"13.4","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"302.5","Tissue RNA - liver [nTPM]":"56.1","Tissue RNA - lung [nTPM]":"27.6","Tissue RNA - lymph node [nTPM]":"10.3","Tissue RNA - medulla oblongata [nTPM]":"9.3","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"73.0","Tissue RNA - pons [nTPM]":"10.9","Tissue RNA - prostate [nTPM]":"79.6","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"44.5","Tissue RNA - skeletal muscle [nTPM]":"20.3","Tissue RNA - skin 1 [nTPM]":"1.9","Tissue RNA - small intestine [nTPM]":"289.7","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"16.6","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"23.5","Tissue RNA - tonsil [nTPM]":"12.3","Tissue RNA - urinary bladder [nTPM]":"6.0","Tissue RNA - vagina [nTPM]":"7.6","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"280.1","Cell RNA - ASC TERT1 [nTPM]":"684.4","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"160.3","Cell RNA - BJ hTERT+ [nTPM]":"1116.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"82.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"209.8","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"172.9","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"130.1","Cell RNA - GAMG [nTPM]":"107.4","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"5.2","Cell RNA - HBEC3-KT [nTPM]":"6.1","Cell RNA - HBF TERT88 [nTPM]":"201.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"229.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"651.1","Cell RNA - hTCEpi [nTPM]":"1.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.4","Cell RNA - hTERT-HME1 [nTPM]":"308.1","Cell RNA - hTERT-RPE1 [nTPM]":"89.4","Cell RNA - HUVEC TERT2 [nTPM]":"59.5","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"135.1","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"6.1","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"303.3","Cell RNA - RH-30 [nTPM]":"139.9","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"5.2","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"31.9","Cell RNA - SuSa [nTPM]":"68.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"165.8","Cell RNA - U-138 MG [nTPM]":"356.4","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"115.7","Cell RNA - U-251 MG [nTPM]":"27.9","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"217.3","Cell RNA - U-87 MG [nTPM]":"42.5","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"7.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"139.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"17.3","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"9.3","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"10.9","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"5.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"74.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"64.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"82.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"273.3","Single Cell Type RNA - Endothelial cells [nTPM]":"6.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"57.8","Single Cell Type RNA - Fibroblasts [nTPM]":"40.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"53.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"10.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.8","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"372.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"125.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"126.0","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"33.6"},{"Gene":"MOG","Gene synonym":["BTN6","BTNL11"],"Ensembl":"ENSG00000204655","Gene description":"Myelin oligodendrocyte glycoprotein","Uniprot":["Q16653"],"Chromosome":"6","Position":"29657002-29672372","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"brain":"73.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"49","RNA single cell type specific nTPM":{"Oligodendrocytes":"472.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"45","RNA cancer specific FPKM":{"glioma":"15.1"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"73.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"1396.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021873"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021873":"AB_1854055"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"8.6","Tissue RNA - cerebral cortex [nTPM]":"73.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"2.6","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"2.6","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"8.4","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"9.9","Tissue RNA - midbrain [nTPM]":"8.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"17.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"8.6","Brain RNA - cerebral cortex [nTPM]":"73.8","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"8.4","Brain RNA - medulla oblongata [nTPM]":"9.9","Brain RNA - midbrain [nTPM]":"8.4","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"17.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"472.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"MORC2","Gene synonym":["AC004542.C22.1","KIAA0852","ZCW3","ZCWCC1"],"Ensembl":"ENSG00000133422","Gene description":"MORC family CW-type zinc finger 2","Uniprot":["Q9Y6X9"],"Chromosome":"22","Position":"30925130-30968774","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"16.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000436","HPA077137"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA000436":"AB_1079404","HPA077137":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.54e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"14.4","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"6.6","Tissue RNA - breast [nTPM]":"16.6","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"8.3","Tissue RNA - cervix [nTPM]":"20.6","Tissue RNA - choroid plexus [nTPM]":"6.6","Tissue RNA - colon [nTPM]":"20.7","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"18.1","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"17.0","Tissue RNA - fallopian tube [nTPM]":"18.7","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"19.2","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"6.5","Tissue RNA - kidney [nTPM]":"16.7","Tissue RNA - liver [nTPM]":"26.9","Tissue RNA - lung [nTPM]":"14.6","Tissue RNA - lymph node [nTPM]":"9.0","Tissue RNA - medulla oblongata [nTPM]":"6.6","Tissue RNA - midbrain [nTPM]":"6.9","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"20.1","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"16.6","Tissue RNA - placenta [nTPM]":"7.5","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"21.8","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"5.8","Tissue RNA - salivary gland [nTPM]":"14.8","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"26.8","Tissue RNA - skin 1 [nTPM]":"19.5","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"7.7","Tissue RNA - spinal cord [nTPM]":"6.4","Tissue RNA - spleen [nTPM]":"19.5","Tissue RNA - stomach 1 [nTPM]":"16.2","Tissue RNA - testis [nTPM]":"45.2","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"15.6","Tissue RNA - tongue [nTPM]":"10.2","Tissue RNA - tonsil [nTPM]":"7.3","Tissue RNA - urinary bladder [nTPM]":"21.2","Tissue RNA - vagina [nTPM]":"18.5","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"19.2","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"20.2","Cell RNA - AN3-CA [nTPM]":"23.3","Cell RNA - ASC diff [nTPM]":"21.4","Cell RNA - ASC TERT1 [nTPM]":"18.3","Cell RNA - BEWO [nTPM]":"15.5","Cell RNA - BJ [nTPM]":"15.6","Cell RNA - BJ hTERT+ [nTPM]":"12.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.7","Cell RNA - CACO-2 [nTPM]":"17.5","Cell RNA - CAPAN-2 [nTPM]":"10.2","Cell RNA - Daudi [nTPM]":"26.9","Cell RNA - EFO-21 [nTPM]":"11.7","Cell RNA - fHDF\/TERT166 [nTPM]":"14.3","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"17.2","Cell RNA - HAP1 [nTPM]":"17.7","Cell RNA - HBEC3-KT [nTPM]":"6.9","Cell RNA - HBF TERT88 [nTPM]":"18.2","Cell RNA - HDLM-2 [nTPM]":"15.5","Cell RNA - HEK 293 [nTPM]":"23.8","Cell RNA - HEL [nTPM]":"20.5","Cell RNA - HeLa [nTPM]":"12.4","Cell RNA - Hep G2 [nTPM]":"15.3","Cell RNA - HHSteC [nTPM]":"15.6","Cell RNA - HL-60 [nTPM]":"18.1","Cell RNA - HMC-1 [nTPM]":"19.8","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"12.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.1","Cell RNA - hTERT-HME1 [nTPM]":"18.9","Cell RNA - hTERT-RPE1 [nTPM]":"12.0","Cell RNA - HUVEC TERT2 [nTPM]":"14.0","Cell RNA - JURKAT [nTPM]":"9.5","Cell RNA - K-562 [nTPM]":"26.3","Cell RNA - Karpas-707 [nTPM]":"19.0","Cell RNA - LHCN-M2 [nTPM]":"17.2","Cell RNA - MCF7 [nTPM]":"23.7","Cell RNA - MOLT-4 [nTPM]":"16.2","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"23.0","Cell RNA - OE19 [nTPM]":"23.9","Cell RNA - PC-3 [nTPM]":"12.6","Cell RNA - REH [nTPM]":"31.5","Cell RNA - RH-30 [nTPM]":"12.8","Cell RNA - RPMI-8226 [nTPM]":"22.9","Cell RNA - RPTEC TERT1 [nTPM]":"12.5","Cell RNA - RT4 [nTPM]":"19.1","Cell RNA - SCLC-21H [nTPM]":"20.5","Cell RNA - SH-SY5Y [nTPM]":"17.2","Cell RNA - SiHa [nTPM]":"18.8","Cell RNA - SK-BR-3 [nTPM]":"21.9","Cell RNA - SK-MEL-30 [nTPM]":"8.8","Cell RNA - SuSa [nTPM]":"19.6","Cell RNA - T-47d [nTPM]":"16.2","Cell RNA - THP-1 [nTPM]":"21.2","Cell RNA - TIME [nTPM]":"16.3","Cell RNA - U-138 MG [nTPM]":"17.8","Cell RNA - U-2 OS [nTPM]":"18.7","Cell RNA - U-2197 [nTPM]":"14.3","Cell RNA - U-251 MG [nTPM]":"12.3","Cell RNA - U-266\/70 [nTPM]":"15.0","Cell RNA - U-266\/84 [nTPM]":"19.0","Cell RNA - U-698 [nTPM]":"22.2","Cell RNA - U-87 MG [nTPM]":"10.3","Cell RNA - U-937 [nTPM]":"9.1","Cell RNA - WM-115 [nTPM]":"13.3","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"12.0","Blood RNA - intermediate monocyte [nTPM]":"2.9","Blood RNA - MAIT T-cell [nTPM]":"10.0","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"15.1","Blood RNA - memory CD8 T-cell [nTPM]":"9.6","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"15.2","Blood RNA - naive CD8 T-cell [nTPM]":"11.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"3.3","Blood RNA - plasmacytoid DC [nTPM]":"3.2","Blood RNA - T-reg [nTPM]":"16.5","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"8.3","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"6.5","Brain RNA - medulla oblongata [nTPM]":"6.6","Brain RNA - midbrain [nTPM]":"6.9","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"6.4","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"4.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"7.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.4","Single Cell Type RNA - dendritic cells [nTPM]":"5.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.3","Single Cell Type RNA - Early spermatids [nTPM]":"30.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.4","Single Cell Type RNA - Fibroblasts [nTPM]":"6.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"8.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.1","Single Cell Type RNA - Late spermatids [nTPM]":"10.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"4.5","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"26.6","Single Cell Type RNA - Spermatogonia [nTPM]":"24.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"7.8","Single Cell Type RNA - Theca cells [nTPM]":"7.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.3","Single Cell Type RNA - Urothelial cells [nTPM]":"5.6"},{"Gene":"MPV17","Gene synonym":["SYM1"],"Ensembl":"ENSG00000115204","Gene description":"Mitochondrial inner membrane protein MPV17","Uniprot":["P39210"],"Chromosome":"2","Position":"27309492-27325680","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"50.2","Tissue RNA - adrenal gland [nTPM]":"86.5","Tissue RNA - amygdala [nTPM]":"56.4","Tissue RNA - appendix [nTPM]":"37.8","Tissue RNA - basal ganglia [nTPM]":"58.1","Tissue RNA - bone marrow [nTPM]":"31.3","Tissue RNA - breast [nTPM]":"39.9","Tissue RNA - cerebellum [nTPM]":"59.1","Tissue RNA - cerebral cortex [nTPM]":"58.4","Tissue RNA - cervix [nTPM]":"36.0","Tissue RNA - choroid plexus [nTPM]":"59.3","Tissue RNA - colon [nTPM]":"32.5","Tissue RNA - duodenum [nTPM]":"25.0","Tissue RNA - endometrium 1 [nTPM]":"37.9","Tissue RNA - epididymis [nTPM]":"47.7","Tissue RNA - esophagus [nTPM]":"32.6","Tissue RNA - fallopian tube [nTPM]":"37.7","Tissue RNA - gallbladder [nTPM]":"36.7","Tissue RNA - heart muscle [nTPM]":"78.2","Tissue RNA - hippocampal formation [nTPM]":"56.3","Tissue RNA - hypothalamus [nTPM]":"59.1","Tissue RNA - kidney [nTPM]":"48.6","Tissue RNA - liver [nTPM]":"22.6","Tissue RNA - lung [nTPM]":"39.1","Tissue RNA - lymph node [nTPM]":"43.2","Tissue RNA - medulla oblongata [nTPM]":"58.8","Tissue RNA - midbrain [nTPM]":"57.1","Tissue RNA - ovary [nTPM]":"43.7","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"70.0","Tissue RNA - pituitary gland [nTPM]":"38.9","Tissue RNA - placenta [nTPM]":"35.0","Tissue RNA - pons [nTPM]":"58.1","Tissue RNA - prostate [nTPM]":"34.1","Tissue RNA - rectum [nTPM]":"34.1","Tissue RNA - retina [nTPM]":"26.7","Tissue RNA - salivary gland [nTPM]":"35.9","Tissue RNA - seminal vesicle [nTPM]":"35.0","Tissue RNA - skeletal muscle [nTPM]":"18.3","Tissue RNA - skin 1 [nTPM]":"32.0","Tissue RNA - small intestine [nTPM]":"27.5","Tissue RNA - smooth muscle [nTPM]":"57.7","Tissue RNA - spinal cord [nTPM]":"56.9","Tissue RNA - spleen [nTPM]":"37.1","Tissue RNA - stomach 1 [nTPM]":"29.1","Tissue RNA - testis [nTPM]":"15.5","Tissue RNA - thalamus [nTPM]":"60.3","Tissue RNA - thymus [nTPM]":"46.0","Tissue RNA - thyroid gland [nTPM]":"51.6","Tissue RNA - tongue [nTPM]":"30.0","Tissue RNA - tonsil [nTPM]":"48.1","Tissue RNA - urinary bladder [nTPM]":"44.9","Tissue RNA - vagina [nTPM]":"28.1","Tissue RNA - white matter [nTPM]":"63.2","Cell RNA - A-431 [nTPM]":"74.1","Cell RNA - A549 [nTPM]":"68.2","Cell RNA - AF22 [nTPM]":"49.7","Cell RNA - AN3-CA [nTPM]":"42.6","Cell RNA - ASC diff [nTPM]":"202.7","Cell RNA - ASC TERT1 [nTPM]":"237.0","Cell RNA - BEWO [nTPM]":"46.6","Cell RNA - BJ [nTPM]":"70.8","Cell RNA - BJ hTERT+ [nTPM]":"143.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"60.7","Cell RNA - CACO-2 [nTPM]":"55.0","Cell RNA - CAPAN-2 [nTPM]":"52.0","Cell RNA - Daudi [nTPM]":"41.5","Cell RNA - EFO-21 [nTPM]":"72.8","Cell RNA - fHDF\/TERT166 [nTPM]":"97.2","Cell RNA - GAMG [nTPM]":"124.0","Cell RNA - HaCaT [nTPM]":"61.3","Cell RNA - HAP1 [nTPM]":"64.1","Cell RNA - HBEC3-KT [nTPM]":"134.1","Cell RNA - HBF TERT88 [nTPM]":"69.5","Cell RNA - HDLM-2 [nTPM]":"56.9","Cell RNA - HEK 293 [nTPM]":"63.7","Cell RNA - HEL [nTPM]":"79.5","Cell RNA - HeLa [nTPM]":"58.8","Cell RNA - Hep G2 [nTPM]":"105.6","Cell RNA - HHSteC [nTPM]":"125.4","Cell RNA - HL-60 [nTPM]":"47.3","Cell RNA - HMC-1 [nTPM]":"48.7","Cell RNA - HSkMC [nTPM]":"229.3","Cell RNA - hTCEpi [nTPM]":"116.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"118.6","Cell RNA - hTERT-HME1 [nTPM]":"169.4","Cell RNA - hTERT-RPE1 [nTPM]":"94.3","Cell RNA - HUVEC TERT2 [nTPM]":"100.2","Cell RNA - JURKAT [nTPM]":"49.8","Cell RNA - K-562 [nTPM]":"77.0","Cell RNA - Karpas-707 [nTPM]":"77.1","Cell RNA - LHCN-M2 [nTPM]":"113.9","Cell RNA - MCF7 [nTPM]":"107.4","Cell RNA - MOLT-4 [nTPM]":"46.9","Cell RNA - NB-4 [nTPM]":"71.5","Cell RNA - NTERA-2 [nTPM]":"55.7","Cell RNA - OE19 [nTPM]":"106.7","Cell RNA - PC-3 [nTPM]":"69.1","Cell RNA - REH [nTPM]":"64.6","Cell RNA - RH-30 [nTPM]":"73.2","Cell RNA - RPMI-8226 [nTPM]":"85.2","Cell RNA - RPTEC TERT1 [nTPM]":"149.2","Cell RNA - RT4 [nTPM]":"58.5","Cell RNA - SCLC-21H [nTPM]":"33.1","Cell RNA - SH-SY5Y [nTPM]":"107.2","Cell RNA - SiHa [nTPM]":"37.6","Cell RNA - SK-BR-3 [nTPM]":"43.7","Cell RNA - SK-MEL-30 [nTPM]":"82.1","Cell RNA - SuSa [nTPM]":"49.3","Cell RNA - T-47d [nTPM]":"49.0","Cell RNA - THP-1 [nTPM]":"60.6","Cell RNA - TIME [nTPM]":"88.6","Cell RNA - U-138 MG [nTPM]":"67.0","Cell RNA - U-2 OS [nTPM]":"68.8","Cell RNA - U-2197 [nTPM]":"83.4","Cell RNA - U-251 MG [nTPM]":"76.4","Cell RNA - U-266\/70 [nTPM]":"108.1","Cell RNA - U-266\/84 [nTPM]":"106.1","Cell RNA - U-698 [nTPM]":"130.4","Cell RNA - U-87 MG [nTPM]":"109.2","Cell RNA - U-937 [nTPM]":"105.4","Cell RNA - WM-115 [nTPM]":"76.1","Blood RNA - basophil [nTPM]":"59.5","Blood RNA - classical monocyte [nTPM]":"93.7","Blood RNA - eosinophil [nTPM]":"42.9","Blood RNA - gdT-cell [nTPM]":"59.3","Blood RNA - intermediate monocyte [nTPM]":"81.4","Blood RNA - MAIT T-cell [nTPM]":"64.4","Blood RNA - memory B-cell [nTPM]":"84.5","Blood RNA - memory CD4 T-cell [nTPM]":"60.5","Blood RNA - memory CD8 T-cell [nTPM]":"67.4","Blood RNA - myeloid DC [nTPM]":"120.5","Blood RNA - naive B-cell [nTPM]":"73.6","Blood RNA - naive CD4 T-cell [nTPM]":"58.0","Blood RNA - naive CD8 T-cell [nTPM]":"67.8","Blood RNA - neutrophil [nTPM]":"7.8","Blood RNA - NK-cell [nTPM]":"76.0","Blood RNA - non-classical monocyte [nTPM]":"81.7","Blood RNA - plasmacytoid DC [nTPM]":"87.4","Blood RNA - T-reg [nTPM]":"81.4","Blood RNA - total PBMC [nTPM]":"92.1","Brain RNA - amygdala [nTPM]":"56.4","Brain RNA - basal ganglia [nTPM]":"58.1","Brain RNA - cerebellum [nTPM]":"59.1","Brain RNA - cerebral cortex [nTPM]":"58.4","Brain RNA - hippocampal formation [nTPM]":"56.3","Brain RNA - hypothalamus [nTPM]":"59.1","Brain RNA - medulla oblongata [nTPM]":"58.8","Brain RNA - midbrain [nTPM]":"57.1","Brain RNA - pons [nTPM]":"58.1","Brain RNA - spinal cord [nTPM]":"56.9","Brain RNA - thalamus [nTPM]":"60.3","Brain RNA - white matter [nTPM]":"63.2","Single Cell Type RNA - Adipocytes [nTPM]":"36.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"26.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"69.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"20.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"52.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"46.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"51.1","Single Cell Type RNA - dendritic cells [nTPM]":"26.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"64.6","Single Cell Type RNA - Ductal cells [nTPM]":"43.3","Single Cell Type RNA - Early spermatids [nTPM]":"27.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.6","Single Cell Type RNA - Endothelial cells [nTPM]":"35.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"21.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"60.2","Single Cell Type RNA - Fibroblasts [nTPM]":"37.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.5","Single Cell Type RNA - granulocytes [nTPM]":"42.5","Single Cell Type RNA - Granulosa cells [nTPM]":"28.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"9.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"116.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"28.5","Single Cell Type RNA - Langerhans cells [nTPM]":"24.0","Single Cell Type RNA - Late spermatids [nTPM]":"34.2","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"33.7","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"38.1","Single Cell Type RNA - Muller glia cells [nTPM]":"38.9","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.7","Single Cell Type RNA - Paneth cells [nTPM]":"12.9","Single Cell Type RNA - Peritubular cells [nTPM]":"35.0","Single Cell Type RNA - Plasma cells [nTPM]":"31.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"87.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.8","Single Cell Type RNA - Spermatocytes [nTPM]":"15.5","Single Cell Type RNA - Spermatogonia [nTPM]":"21.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.4","Single Cell Type RNA - T-cells [nTPM]":"22.2","Single Cell Type RNA - Theca cells [nTPM]":"41.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.7","Single Cell Type RNA - Urothelial cells [nTPM]":"30.7"},{"Gene":"MPZ","Gene synonym":["CMT1","CMT1B","CMT2I","CMT2J","HMSNIB","P0"],"Ensembl":"ENSG00000158887","Gene description":"Myelin protein zero","Uniprot":["P25189"],"Chromosome":"1","Position":"161304735-161309968","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Dejerine-Sottas syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Sertoli cells":"6.6","Skeletal myocytes":"9.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"melanoma":"83.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"WM-115":"139.3"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"olfactory bulb":"2.9","pons and medulla":"1.3"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"10","RNA pig brain regional specific nTPM":{"spinal cord":"2142.4"},"Antibody":["HPA068925"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA068925":"AB_2732123"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.1","Tissue RNA - adrenal gland [nTPM]":"6.9","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"12.6","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"8.3","Tissue RNA - choroid plexus [nTPM]":"1.4","Tissue RNA - colon [nTPM]":"22.3","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"5.3","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"15.2","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"3.1","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"12.2","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"15.8","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"5.1","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"4.4","Tissue RNA - stomach 1 [nTPM]":"7.6","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"3.7","Tissue RNA - tongue [nTPM]":"18.4","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"9.5","Tissue RNA - vagina [nTPM]":"15.9","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"2.3","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"31.0","Cell RNA - HHSteC [nTPM]":"1.2","Cell RNA - HL-60 [nTPM]":"4.7","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"4.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"2.8","Cell RNA - JURKAT [nTPM]":"1.9","Cell RNA - K-562 [nTPM]":"9.9","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"4.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"7.6","Cell RNA - NTERA-2 [nTPM]":"1.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"14.0","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"2.7","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"2.7","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"1.2","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"17.5","Cell RNA - WM-115 [nTPM]":"139.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"2.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"3.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"MPZL2","Gene synonym":["EVA","EVA1"],"Ensembl":"ENSG00000149573","Gene description":"Myelin protein zero like 2","Uniprot":["O60487"],"Chromosome":"11","Position":"118253416-118264536","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"222.5","urinary bladder":"155.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"332.5","Basal prostatic cells":"504.4","Basal respiratory cells":"289.1","Squamous epithelial cells":"336.4","Suprabasal keratinocytes":"467.4","Urothelial cells":"489.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"11.6","intermediate monocyte":"9.2","myeloid DC":"17.0","neutrophil":"13.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"17.0","granulocytes":"13.2","monocytes":"11.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"120.9","EFO-21":"130.4","HaCaT":"166.9","RT4":"321.7","TIME":"351.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"spinal cord":"38.8"},"Antibody":["HPA060740"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA060740":"AB_2684352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.6","Tissue RNA - adrenal gland [nTPM]":"4.7","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"11.9","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"19.6","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"4.8","Tissue RNA - cervix [nTPM]":"56.7","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"31.1","Tissue RNA - duodenum [nTPM]":"17.0","Tissue RNA - endometrium 1 [nTPM]":"16.9","Tissue RNA - epididymis [nTPM]":"38.5","Tissue RNA - esophagus [nTPM]":"222.5","Tissue RNA - fallopian tube [nTPM]":"46.4","Tissue RNA - gallbladder [nTPM]":"33.5","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"26.4","Tissue RNA - liver [nTPM]":"23.2","Tissue RNA - lung [nTPM]":"47.0","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"13.5","Tissue RNA - parathyroid gland [nTPM]":"27.1","Tissue RNA - pituitary gland [nTPM]":"10.7","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"48.6","Tissue RNA - rectum [nTPM]":"30.8","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"58.0","Tissue RNA - seminal vesicle [nTPM]":"69.5","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"38.8","Tissue RNA - small intestine [nTPM]":"11.3","Tissue RNA - smooth muscle [nTPM]":"14.7","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"37.0","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"3.4","Tissue RNA - thymus [nTPM]":"18.1","Tissue RNA - thyroid gland [nTPM]":"30.3","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"52.6","Tissue RNA - urinary bladder [nTPM]":"155.9","Tissue RNA - vagina [nTPM]":"120.5","Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"65.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"27.0","Cell RNA - CAPAN-2 [nTPM]":"120.9","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"130.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"166.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"38.9","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"9.5","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"35.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"90.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"86.8","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"51.3","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"34.2","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"6.4","Cell RNA - RPTEC TERT1 [nTPM]":"14.9","Cell RNA - RT4 [nTPM]":"321.7","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"5.8","Cell RNA - SK-BR-3 [nTPM]":"61.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"26.1","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"351.9","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"2.3","Blood RNA - classical monocyte [nTPM]":"11.6","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"9.2","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"17.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"13.2","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"3.8","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"4.8","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"3.4","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"123.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"332.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"504.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"289.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"127.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"221.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"128.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"52.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"39.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"91.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.8","Single Cell Type RNA - Endothelial cells [nTPM]":"33.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.3","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"51.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"8.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"194.0","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"45.3","Single Cell Type RNA - Hepatocytes [nTPM]":"16.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.3","Single Cell Type RNA - Ionocytes [nTPM]":"81.4","Single Cell Type RNA - Kupffer cells [nTPM]":"6.4","Single Cell Type RNA - Langerhans cells [nTPM]":"27.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"68.2","Single Cell Type RNA - Paneth cells [nTPM]":"20.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"186.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"65.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"336.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"467.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.8","Single Cell Type RNA - T-cells [nTPM]":"5.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.4","Single Cell Type RNA - Urothelial cells [nTPM]":"489.7"},{"Gene":"MRE11","Gene synonym":["ATLD","MRE11A"],"Ensembl":"ENSG00000020922","Gene description":"MRE11 homolog, double strand break repair nuclease","Uniprot":["P49959"],"Chromosome":"11","Position":"94415570-94493885","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction","Meiosis"],"Molecular function":["Endonuclease","Exonuclease","Hydrolase","Nuclease"],"Disease involvement":["Cancer-related genes","Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"28.9","Cytotrophoblasts":"39.2","Granulosa cells":"34.1","Syncytiotrophoblasts":"28.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002691","CAB004081"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB004081":"AB_2145100","HPA002691":"AB_1079409"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.14e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"6.1","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"11.7","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"22.6","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"3.4","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"6.0","Tissue RNA - colon [nTPM]":"7.6","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"11.7","Tissue RNA - epididymis [nTPM]":"8.9","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"7.9","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"5.0","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"6.0","Tissue RNA - liver [nTPM]":"6.4","Tissue RNA - lung [nTPM]":"7.7","Tissue RNA - lymph node [nTPM]":"12.6","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"11.1","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"9.3","Tissue RNA - rectum [nTPM]":"11.5","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"15.6","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"12.7","Tissue RNA - stomach 1 [nTPM]":"7.3","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"7.4","Tissue RNA - tongue [nTPM]":"5.4","Tissue RNA - tonsil [nTPM]":"16.1","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"6.7","Cell RNA - A-431 [nTPM]":"21.5","Cell RNA - A549 [nTPM]":"21.5","Cell RNA - AF22 [nTPM]":"39.9","Cell RNA - AN3-CA [nTPM]":"5.0","Cell RNA - ASC diff [nTPM]":"13.1","Cell RNA - ASC TERT1 [nTPM]":"18.2","Cell RNA - BEWO [nTPM]":"22.8","Cell RNA - BJ [nTPM]":"29.4","Cell RNA - BJ hTERT+ [nTPM]":"19.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.6","Cell RNA - CACO-2 [nTPM]":"39.4","Cell RNA - CAPAN-2 [nTPM]":"43.3","Cell RNA - Daudi [nTPM]":"55.8","Cell RNA - EFO-21 [nTPM]":"47.0","Cell RNA - fHDF\/TERT166 [nTPM]":"15.3","Cell RNA - GAMG [nTPM]":"32.5","Cell RNA - HaCaT [nTPM]":"40.1","Cell RNA - HAP1 [nTPM]":"33.7","Cell RNA - HBEC3-KT [nTPM]":"22.1","Cell RNA - HBF TERT88 [nTPM]":"34.1","Cell RNA - HDLM-2 [nTPM]":"37.5","Cell RNA - HEK 293 [nTPM]":"20.0","Cell RNA - HEL [nTPM]":"48.7","Cell RNA - HeLa [nTPM]":"31.5","Cell RNA - Hep G2 [nTPM]":"22.7","Cell RNA - HHSteC [nTPM]":"6.0","Cell RNA - HL-60 [nTPM]":"32.7","Cell RNA - HMC-1 [nTPM]":"33.6","Cell RNA - HSkMC [nTPM]":"12.8","Cell RNA - hTCEpi [nTPM]":"13.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.7","Cell RNA - hTERT-HME1 [nTPM]":"21.0","Cell RNA - hTERT-RPE1 [nTPM]":"11.7","Cell RNA - HUVEC TERT2 [nTPM]":"23.0","Cell RNA - JURKAT [nTPM]":"26.8","Cell RNA - K-562 [nTPM]":"34.9","Cell RNA - Karpas-707 [nTPM]":"35.6","Cell RNA - LHCN-M2 [nTPM]":"20.9","Cell RNA - MCF7 [nTPM]":"15.5","Cell RNA - MOLT-4 [nTPM]":"33.2","Cell RNA - NB-4 [nTPM]":"30.5","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"49.3","Cell RNA - PC-3 [nTPM]":"23.3","Cell RNA - REH [nTPM]":"29.0","Cell RNA - RH-30 [nTPM]":"35.3","Cell RNA - RPMI-8226 [nTPM]":"28.1","Cell RNA - RPTEC TERT1 [nTPM]":"16.8","Cell RNA - RT4 [nTPM]":"29.6","Cell RNA - SCLC-21H [nTPM]":"14.1","Cell RNA - SH-SY5Y [nTPM]":"19.8","Cell RNA - SiHa [nTPM]":"40.6","Cell RNA - SK-BR-3 [nTPM]":"26.0","Cell RNA - SK-MEL-30 [nTPM]":"8.6","Cell RNA - SuSa [nTPM]":"33.2","Cell RNA - T-47d [nTPM]":"43.4","Cell RNA - THP-1 [nTPM]":"19.3","Cell RNA - TIME [nTPM]":"16.9","Cell RNA - U-138 MG [nTPM]":"38.7","Cell RNA - U-2 OS [nTPM]":"28.6","Cell RNA - U-2197 [nTPM]":"33.9","Cell RNA - U-251 MG [nTPM]":"21.5","Cell RNA - U-266\/70 [nTPM]":"8.8","Cell RNA - U-266\/84 [nTPM]":"33.2","Cell RNA - U-698 [nTPM]":"54.4","Cell RNA - U-87 MG [nTPM]":"10.4","Cell RNA - U-937 [nTPM]":"50.3","Cell RNA - WM-115 [nTPM]":"31.5","Blood RNA - basophil [nTPM]":"5.7","Blood RNA - classical monocyte [nTPM]":"8.0","Blood RNA - eosinophil [nTPM]":"6.5","Blood RNA - gdT-cell [nTPM]":"8.2","Blood RNA - intermediate monocyte [nTPM]":"10.0","Blood RNA - MAIT T-cell [nTPM]":"8.3","Blood RNA - memory B-cell [nTPM]":"6.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"8.9","Blood RNA - myeloid DC [nTPM]":"11.6","Blood RNA - naive B-cell [nTPM]":"6.9","Blood RNA - naive CD4 T-cell [nTPM]":"5.1","Blood RNA - naive CD8 T-cell [nTPM]":"8.4","Blood RNA - neutrophil [nTPM]":"3.8","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"8.7","Blood RNA - T-reg [nTPM]":"8.8","Blood RNA - total PBMC [nTPM]":"6.7","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"3.4","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"6.7","Single Cell Type RNA - Adipocytes [nTPM]":"23.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"9.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.2","Single Cell Type RNA - dendritic cells [nTPM]":"20.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.2","Single Cell Type RNA - Endothelial cells [nTPM]":"8.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.8","Single Cell Type RNA - Fibroblasts [nTPM]":"8.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.3","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"34.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"10.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"9.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.0","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"16.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MSRB3","Gene synonym":["DFNB74","DKFZp686C1178","FLJ36866"],"Ensembl":"ENSG00000174099","Gene description":"Methionine sulfoxide reductase B3","Uniprot":["Q8IXL7"],"Chromosome":"12","Position":"65278643-65491430","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Cardiomyocytes":"2801.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"41.6"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"41.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"126.1","hTERT-RPE1":"110.6","U-937":"106.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014432"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014432":"AB_1854146"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.84e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.85e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.17e-4"},"Tissue RNA - adipose tissue [nTPM]":"44.9","Tissue RNA - adrenal gland [nTPM]":"10.7","Tissue RNA - amygdala [nTPM]":"12.9","Tissue RNA - appendix [nTPM]":"20.9","Tissue RNA - basal ganglia [nTPM]":"13.6","Tissue RNA - bone marrow [nTPM]":"21.2","Tissue RNA - breast [nTPM]":"26.3","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"29.5","Tissue RNA - choroid plexus [nTPM]":"18.8","Tissue RNA - colon [nTPM]":"108.0","Tissue RNA - duodenum [nTPM]":"11.9","Tissue RNA - endometrium 1 [nTPM]":"85.8","Tissue RNA - epididymis [nTPM]":"20.1","Tissue RNA - esophagus [nTPM]":"63.0","Tissue RNA - fallopian tube [nTPM]":"41.4","Tissue RNA - gallbladder [nTPM]":"33.2","Tissue RNA - heart muscle [nTPM]":"90.8","Tissue RNA - hippocampal formation [nTPM]":"11.9","Tissue RNA - hypothalamus [nTPM]":"18.3","Tissue RNA - kidney [nTPM]":"10.1","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"30.6","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"15.9","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"3.2","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"25.2","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"52.7","Tissue RNA - rectum [nTPM]":"27.8","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"10.8","Tissue RNA - seminal vesicle [nTPM]":"103.0","Tissue RNA - skeletal muscle [nTPM]":"104.0","Tissue RNA - skin 1 [nTPM]":"9.7","Tissue RNA - small intestine [nTPM]":"25.6","Tissue RNA - smooth muscle [nTPM]":"123.9","Tissue RNA - spinal cord [nTPM]":"14.6","Tissue RNA - spleen [nTPM]":"13.6","Tissue RNA - stomach 1 [nTPM]":"36.2","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"18.2","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"14.5","Tissue RNA - tongue [nTPM]":"69.2","Tissue RNA - tonsil [nTPM]":"3.9","Tissue RNA - urinary bladder [nTPM]":"60.9","Tissue RNA - vagina [nTPM]":"23.7","Tissue RNA - white matter [nTPM]":"11.8","Cell RNA - A-431 [nTPM]":"8.8","Cell RNA - A549 [nTPM]":"19.2","Cell RNA - AF22 [nTPM]":"16.4","Cell RNA - AN3-CA [nTPM]":"75.9","Cell RNA - ASC diff [nTPM]":"71.6","Cell RNA - ASC TERT1 [nTPM]":"63.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"87.0","Cell RNA - BJ hTERT+ [nTPM]":"92.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.8","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"18.3","Cell RNA - fHDF\/TERT166 [nTPM]":"126.1","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"7.7","Cell RNA - HBEC3-KT [nTPM]":"22.1","Cell RNA - HBF TERT88 [nTPM]":"30.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"15.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"16.7","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"46.6","Cell RNA - HL-60 [nTPM]":"47.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"33.4","Cell RNA - hTCEpi [nTPM]":"11.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.1","Cell RNA - hTERT-HME1 [nTPM]":"39.0","Cell RNA - hTERT-RPE1 [nTPM]":"110.6","Cell RNA - HUVEC TERT2 [nTPM]":"68.2","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"76.8","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"11.0","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"10.4","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"22.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"7.5","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"7.9","Cell RNA - SiHa [nTPM]":"30.0","Cell RNA - SK-BR-3 [nTPM]":"1.8","Cell RNA - SK-MEL-30 [nTPM]":"21.9","Cell RNA - SuSa [nTPM]":"16.8","Cell RNA - T-47d [nTPM]":"14.1","Cell RNA - THP-1 [nTPM]":"44.5","Cell RNA - TIME [nTPM]":"78.9","Cell RNA - U-138 MG [nTPM]":"42.3","Cell RNA - U-2 OS [nTPM]":"22.8","Cell RNA - U-2197 [nTPM]":"19.5","Cell RNA - U-251 MG [nTPM]":"34.2","Cell RNA - U-266\/70 [nTPM]":"8.0","Cell RNA - U-266\/84 [nTPM]":"6.7","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"11.5","Cell RNA - U-937 [nTPM]":"106.7","Cell RNA - WM-115 [nTPM]":"26.9","Blood RNA - basophil [nTPM]":"15.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"41.6","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"6.8","Blood RNA - NK-cell [nTPM]":"8.3","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"10.8","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"12.9","Brain RNA - basal ganglia [nTPM]":"13.6","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"11.9","Brain RNA - hypothalamus [nTPM]":"18.3","Brain RNA - medulla oblongata [nTPM]":"15.9","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"14.6","Brain RNA - thalamus [nTPM]":"18.2","Brain RNA - white matter [nTPM]":"11.8","Single Cell Type RNA - Adipocytes [nTPM]":"55.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"76.7","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2801.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"1.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"8.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.7","Single Cell Type RNA - Endothelial cells [nTPM]":"154.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"108.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"4.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"62.8","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"44.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"116.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.6","Single Cell Type RNA - Sertoli cells [nTPM]":"105.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"218.7","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"2.4","Single Cell Type RNA - Theca cells [nTPM]":"10.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"MT-ATP6","Gene synonym":["ATP6","ATPase-6","MTATP6","RP","Su6m"],"Ensembl":"ENSG00000198899","Gene description":"Mitochondrially encoded ATP synthase membrane subunit 6","Uniprot":["P00846"],"Chromosome":"MT","Position":"8527-9207","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["ATP synthesis","Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","Leber hereditary optic neuropathy","Leigh syndrome","Neuropathy","Primary mitochondrial disease","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"240231.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cardiomyocytes":"183462.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"15099.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"15099.8"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HeLa":"81002.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.64e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"},"Tissue RNA - adipose tissue [nTPM]":"30620.5","Tissue RNA - adrenal gland [nTPM]":"49902.8","Tissue RNA - amygdala [nTPM]":"78564.9","Tissue RNA - appendix [nTPM]":"5757.5","Tissue RNA - basal ganglia [nTPM]":"78683.9","Tissue RNA - bone marrow [nTPM]":"5263.3","Tissue RNA - breast [nTPM]":"24700.9","Tissue RNA - cerebellum [nTPM]":"71753.6","Tissue RNA - cerebral cortex [nTPM]":"111983.3","Tissue RNA - cervix [nTPM]":"10531.0","Tissue RNA - choroid plexus [nTPM]":"92461.0","Tissue RNA - colon [nTPM]":"34888.0","Tissue RNA - duodenum [nTPM]":"15959.6","Tissue RNA - endometrium 1 [nTPM]":"12648.9","Tissue RNA - epididymis [nTPM]":"6224.7","Tissue RNA - esophagus [nTPM]":"18979.9","Tissue RNA - fallopian tube [nTPM]":"12132.1","Tissue RNA - gallbladder [nTPM]":"5215.3","Tissue RNA - heart muscle [nTPM]":"240231.8","Tissue RNA - hippocampal formation [nTPM]":"73845.3","Tissue RNA - hypothalamus [nTPM]":"79126.1","Tissue RNA - kidney [nTPM]":"97663.8","Tissue RNA - liver [nTPM]":"108393.4","Tissue RNA - lung [nTPM]":"13251.1","Tissue RNA - lymph node [nTPM]":"4613.5","Tissue RNA - medulla oblongata [nTPM]":"94236.1","Tissue RNA - midbrain [nTPM]":"80705.7","Tissue RNA - ovary [nTPM]":"11001.6","Tissue RNA - pancreas [nTPM]":"26731.7","Tissue RNA - parathyroid gland [nTPM]":"15286.5","Tissue RNA - pituitary gland [nTPM]":"17490.5","Tissue RNA - placenta [nTPM]":"7337.2","Tissue RNA - pons [nTPM]":"87375.8","Tissue RNA - prostate [nTPM]":"26534.4","Tissue RNA - rectum [nTPM]":"11997.9","Tissue RNA - retina [nTPM]":"12678.8","Tissue RNA - salivary gland [nTPM]":"19672.9","Tissue RNA - seminal vesicle [nTPM]":"7061.2","Tissue RNA - skeletal muscle [nTPM]":"110786.8","Tissue RNA - skin 1 [nTPM]":"21566.0","Tissue RNA - small intestine [nTPM]":"29555.6","Tissue RNA - smooth muscle [nTPM]":"5826.0","Tissue RNA - spinal cord [nTPM]":"66562.7","Tissue RNA - spleen [nTPM]":"15489.6","Tissue RNA - stomach 1 [nTPM]":"42384.5","Tissue RNA - testis [nTPM]":"15009.7","Tissue RNA - thalamus [nTPM]":"82151.7","Tissue RNA - thymus [nTPM]":"2880.7","Tissue RNA - thyroid gland [nTPM]":"17077.7","Tissue RNA - tongue [nTPM]":"67112.7","Tissue RNA - tonsil [nTPM]":"4344.5","Tissue RNA - urinary bladder [nTPM]":"21210.2","Tissue RNA - vagina [nTPM]":"12968.0","Tissue RNA - white matter [nTPM]":"67597.2","Cell RNA - A-431 [nTPM]":"5618.9","Cell RNA - A549 [nTPM]":"8971.4","Cell RNA - AF22 [nTPM]":"6145.8","Cell RNA - AN3-CA [nTPM]":"9667.8","Cell RNA - ASC diff [nTPM]":"11469.9","Cell RNA - ASC TERT1 [nTPM]":"2606.5","Cell RNA - BEWO [nTPM]":"4002.9","Cell RNA - BJ [nTPM]":"8017.4","Cell RNA - BJ hTERT+ [nTPM]":"1465.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1068.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1770.2","Cell RNA - CACO-2 [nTPM]":"10629.5","Cell RNA - CAPAN-2 [nTPM]":"5953.7","Cell RNA - Daudi [nTPM]":"9842.8","Cell RNA - EFO-21 [nTPM]":"3325.6","Cell RNA - fHDF\/TERT166 [nTPM]":"4356.6","Cell RNA - GAMG [nTPM]":"1640.3","Cell RNA - HaCaT [nTPM]":"11849.7","Cell RNA - HAP1 [nTPM]":"653.2","Cell RNA - HBEC3-KT [nTPM]":"6255.4","Cell RNA - HBF TERT88 [nTPM]":"1954.9","Cell RNA - HDLM-2 [nTPM]":"7091.2","Cell RNA - HEK 293 [nTPM]":"5605.0","Cell RNA - HEL [nTPM]":"8645.7","Cell RNA - HeLa [nTPM]":"81002.5","Cell RNA - Hep G2 [nTPM]":"18778.0","Cell RNA - HHSteC [nTPM]":"1945.0","Cell RNA - HL-60 [nTPM]":"5183.5","Cell RNA - HMC-1 [nTPM]":"10726.9","Cell RNA - HSkMC [nTPM]":"4289.5","Cell RNA - hTCEpi [nTPM]":"5409.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1909.8","Cell RNA - hTERT-HME1 [nTPM]":"1824.4","Cell RNA - hTERT-RPE1 [nTPM]":"7406.7","Cell RNA - HUVEC TERT2 [nTPM]":"1920.7","Cell RNA - JURKAT [nTPM]":"5418.1","Cell RNA - K-562 [nTPM]":"5810.5","Cell RNA - Karpas-707 [nTPM]":"6963.2","Cell RNA - LHCN-M2 [nTPM]":"4174.7","Cell RNA - MCF7 [nTPM]":"15671.4","Cell RNA - MOLT-4 [nTPM]":"3204.2","Cell RNA - NB-4 [nTPM]":"13620.4","Cell RNA - NTERA-2 [nTPM]":"1620.4","Cell RNA - OE19 [nTPM]":"4244.5","Cell RNA - PC-3 [nTPM]":"3674.4","Cell RNA - REH [nTPM]":"3985.7","Cell RNA - RH-30 [nTPM]":"2622.4","Cell RNA - RPMI-8226 [nTPM]":"6104.2","Cell RNA - RPTEC TERT1 [nTPM]":"10727.8","Cell RNA - RT4 [nTPM]":"13879.3","Cell RNA - SCLC-21H [nTPM]":"3495.2","Cell RNA - SH-SY5Y [nTPM]":"4452.8","Cell RNA - SiHa [nTPM]":"2870.3","Cell RNA - SK-BR-3 [nTPM]":"6024.9","Cell RNA - SK-MEL-30 [nTPM]":"6026.0","Cell RNA - SuSa [nTPM]":"10017.9","Cell RNA - T-47d [nTPM]":"6477.5","Cell RNA - THP-1 [nTPM]":"17539.6","Cell RNA - TIME [nTPM]":"10178.1","Cell RNA - U-138 MG [nTPM]":"4280.9","Cell RNA - U-2 OS [nTPM]":"6317.4","Cell RNA - U-2197 [nTPM]":"7166.3","Cell RNA - U-251 MG [nTPM]":"5880.9","Cell RNA - U-266\/70 [nTPM]":"3051.9","Cell RNA - U-266\/84 [nTPM]":"4303.3","Cell RNA - U-698 [nTPM]":"7137.5","Cell RNA - U-87 MG [nTPM]":"3739.9","Cell RNA - U-937 [nTPM]":"10744.5","Cell RNA - WM-115 [nTPM]":"2455.0","Blood RNA - basophil [nTPM]":"15099.8","Blood RNA - classical monocyte [nTPM]":"2475.3","Blood RNA - eosinophil [nTPM]":"4245.7","Blood RNA - gdT-cell [nTPM]":"1346.3","Blood RNA - intermediate monocyte [nTPM]":"1650.5","Blood RNA - MAIT T-cell [nTPM]":"1689.2","Blood RNA - memory B-cell [nTPM]":"2678.1","Blood RNA - memory CD4 T-cell [nTPM]":"1534.6","Blood RNA - memory CD8 T-cell [nTPM]":"1712.3","Blood RNA - myeloid DC [nTPM]":"1211.4","Blood RNA - naive B-cell [nTPM]":"2550.5","Blood RNA - naive CD4 T-cell [nTPM]":"1774.0","Blood RNA - naive CD8 T-cell [nTPM]":"2220.6","Blood RNA - neutrophil [nTPM]":"2427.2","Blood RNA - NK-cell [nTPM]":"1828.9","Blood RNA - non-classical monocyte [nTPM]":"1841.1","Blood RNA - plasmacytoid DC [nTPM]":"1470.9","Blood RNA - T-reg [nTPM]":"1232.4","Blood RNA - total PBMC [nTPM]":"1223.2","Brain RNA - amygdala [nTPM]":"78564.9","Brain RNA - basal ganglia [nTPM]":"78683.9","Brain RNA - cerebellum [nTPM]":"71753.6","Brain RNA - cerebral cortex [nTPM]":"111983.3","Brain RNA - hippocampal formation [nTPM]":"73845.3","Brain RNA - hypothalamus [nTPM]":"79126.1","Brain RNA - medulla oblongata [nTPM]":"94236.1","Brain RNA - midbrain [nTPM]":"80705.7","Brain RNA - pons [nTPM]":"87375.8","Brain RNA - spinal cord [nTPM]":"66562.7","Brain RNA - thalamus [nTPM]":"82151.7","Brain RNA - white matter [nTPM]":"67597.2","Single Cell Type RNA - Adipocytes [nTPM]":"4123.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1487.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1804.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6867.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2903.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6184.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4172.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7102.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4343.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7054.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"183462.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"11539.8","Single Cell Type RNA - Club cells [nTPM]":"3367.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"6422.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"6110.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"15211.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1880.2","Single Cell Type RNA - Ductal cells [nTPM]":"2059.0","Single Cell Type RNA - Early spermatids [nTPM]":"908.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7527.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6522.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7371.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3995.8","Single Cell Type RNA - Erythroid cells [nTPM]":"17562.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3405.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6067.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6569.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13453.0","Single Cell Type RNA - granulocytes [nTPM]":"2064.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20320.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9969.1","Single Cell Type RNA - Hepatocytes [nTPM]":"26635.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10468.7","Single Cell Type RNA - Ionocytes [nTPM]":"2803.5","Single Cell Type RNA - Kupffer cells [nTPM]":"16148.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2386.4","Single Cell Type RNA - Late spermatids [nTPM]":"4627.8","Single Cell Type RNA - Leydig cells [nTPM]":"7672.0","Single Cell Type RNA - Macrophages [nTPM]":"5539.3","Single Cell Type RNA - Melanocytes [nTPM]":"2534.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4773.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"4080.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2818.6","Single Cell Type RNA - Paneth cells [nTPM]":"9241.3","Single Cell Type RNA - Peritubular cells [nTPM]":"4966.1","Single Cell Type RNA - Plasma cells [nTPM]":"7780.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4657.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24094.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14129.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3106.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6304.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11559.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7641.7","Single Cell Type RNA - Spermatocytes [nTPM]":"5682.1","Single Cell Type RNA - Spermatogonia [nTPM]":"5225.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5947.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3034.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"6304.5","Single Cell Type RNA - Theca cells [nTPM]":"12298.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10197.0","Single Cell Type RNA - Urothelial cells [nTPM]":"7899.3"},{"Gene":"MT-CO1","Gene synonym":["COI","COX1","MTCO1"],"Ensembl":"ENSG00000198804","Gene description":"Mitochondrially encoded cytochrome c oxidase I","Uniprot":["P00395"],"Chromosome":"MT","Position":"5904-7445","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Deafness","Disease variant","Leber hereditary optic neuropathy","Non-syndromic deafness","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"222644.8","heart muscle":"255389.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"107039.5","Hepatocytes":"59794.3","Proximal enterocytes":"98329.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"54167.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016241","HPA069328"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB016241":"AB_2229888","HPA069328":"AB_2686122"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"22006.8","Tissue RNA - adrenal gland [nTPM]":"46968.9","Tissue RNA - amygdala [nTPM]":"171347.0","Tissue RNA - appendix [nTPM]":"8727.7","Tissue RNA - basal ganglia [nTPM]":"151652.8","Tissue RNA - bone marrow [nTPM]":"11321.8","Tissue RNA - breast [nTPM]":"17952.5","Tissue RNA - cerebellum [nTPM]":"132201.9","Tissue RNA - cerebral cortex [nTPM]":"222644.8","Tissue RNA - cervix [nTPM]":"10440.9","Tissue RNA - choroid plexus [nTPM]":"179120.2","Tissue RNA - colon [nTPM]":"42606.0","Tissue RNA - duodenum [nTPM]":"27505.7","Tissue RNA - endometrium 1 [nTPM]":"11582.9","Tissue RNA - epididymis [nTPM]":"14226.0","Tissue RNA - esophagus [nTPM]":"20791.8","Tissue RNA - fallopian tube [nTPM]":"10700.5","Tissue RNA - gallbladder [nTPM]":"11452.7","Tissue RNA - heart muscle [nTPM]":"255389.3","Tissue RNA - hippocampal formation [nTPM]":"151507.6","Tissue RNA - hypothalamus [nTPM]":"137459.2","Tissue RNA - kidney [nTPM]":"63061.8","Tissue RNA - liver [nTPM]":"96575.5","Tissue RNA - lung [nTPM]":"12744.7","Tissue RNA - lymph node [nTPM]":"9111.4","Tissue RNA - medulla oblongata [nTPM]":"176794.8","Tissue RNA - midbrain [nTPM]":"152802.2","Tissue RNA - ovary [nTPM]":"8124.5","Tissue RNA - pancreas [nTPM]":"19467.4","Tissue RNA - parathyroid gland [nTPM]":"41236.2","Tissue RNA - pituitary gland [nTPM]":"7420.2","Tissue RNA - placenta [nTPM]":"10527.8","Tissue RNA - pons [nTPM]":"168465.9","Tissue RNA - prostate [nTPM]":"12427.0","Tissue RNA - rectum [nTPM]":"28389.7","Tissue RNA - retina [nTPM]":"12503.0","Tissue RNA - salivary gland [nTPM]":"23260.1","Tissue RNA - seminal vesicle [nTPM]":"17753.2","Tissue RNA - skeletal muscle [nTPM]":"147209.5","Tissue RNA - skin 1 [nTPM]":"26849.0","Tissue RNA - small intestine [nTPM]":"35366.3","Tissue RNA - smooth muscle [nTPM]":"13146.2","Tissue RNA - spinal cord [nTPM]":"138626.1","Tissue RNA - spleen [nTPM]":"16284.7","Tissue RNA - stomach 1 [nTPM]":"44852.9","Tissue RNA - testis [nTPM]":"10932.5","Tissue RNA - thalamus [nTPM]":"176888.2","Tissue RNA - thymus [nTPM]":"7461.1","Tissue RNA - thyroid gland [nTPM]":"14056.3","Tissue RNA - tongue [nTPM]":"184587.7","Tissue RNA - tonsil [nTPM]":"8381.2","Tissue RNA - urinary bladder [nTPM]":"17415.3","Tissue RNA - vagina [nTPM]":"10559.7","Tissue RNA - white matter [nTPM]":"131378.4","Cell RNA - A-431 [nTPM]":"5837.6","Cell RNA - A549 [nTPM]":"8554.3","Cell RNA - AF22 [nTPM]":"11384.1","Cell RNA - AN3-CA [nTPM]":"12431.0","Cell RNA - ASC diff [nTPM]":"25510.2","Cell RNA - ASC TERT1 [nTPM]":"11563.1","Cell RNA - BEWO [nTPM]":"12037.2","Cell RNA - BJ [nTPM]":"12867.2","Cell RNA - BJ hTERT+ [nTPM]":"4284.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3189.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5257.4","Cell RNA - CACO-2 [nTPM]":"10383.6","Cell RNA - CAPAN-2 [nTPM]":"18320.5","Cell RNA - Daudi [nTPM]":"15138.9","Cell RNA - EFO-21 [nTPM]":"6040.7","Cell RNA - fHDF\/TERT166 [nTPM]":"9857.6","Cell RNA - GAMG [nTPM]":"3118.2","Cell RNA - HaCaT [nTPM]":"21430.9","Cell RNA - HAP1 [nTPM]":"1326.6","Cell RNA - HBEC3-KT [nTPM]":"11407.4","Cell RNA - HBF TERT88 [nTPM]":"4515.1","Cell RNA - HDLM-2 [nTPM]":"7226.0","Cell RNA - HEK 293 [nTPM]":"8040.6","Cell RNA - HEL [nTPM]":"9130.6","Cell RNA - HeLa [nTPM]":"54167.9","Cell RNA - Hep G2 [nTPM]":"19725.4","Cell RNA - HHSteC [nTPM]":"3521.2","Cell RNA - HL-60 [nTPM]":"5336.1","Cell RNA - HMC-1 [nTPM]":"11055.5","Cell RNA - HSkMC [nTPM]":"13603.9","Cell RNA - hTCEpi [nTPM]":"11589.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3149.9","Cell RNA - hTERT-HME1 [nTPM]":"6917.5","Cell RNA - hTERT-RPE1 [nTPM]":"14668.4","Cell RNA - HUVEC TERT2 [nTPM]":"3902.1","Cell RNA - JURKAT [nTPM]":"8485.5","Cell RNA - K-562 [nTPM]":"5916.3","Cell RNA - Karpas-707 [nTPM]":"10551.1","Cell RNA - LHCN-M2 [nTPM]":"9525.6","Cell RNA - MCF7 [nTPM]":"14037.0","Cell RNA - MOLT-4 [nTPM]":"4378.4","Cell RNA - NB-4 [nTPM]":"23591.9","Cell RNA - NTERA-2 [nTPM]":"2905.0","Cell RNA - OE19 [nTPM]":"7814.2","Cell RNA - PC-3 [nTPM]":"6900.5","Cell RNA - REH [nTPM]":"5664.0","Cell RNA - RH-30 [nTPM]":"3401.6","Cell RNA - RPMI-8226 [nTPM]":"9177.9","Cell RNA - RPTEC TERT1 [nTPM]":"15910.6","Cell RNA - RT4 [nTPM]":"15016.1","Cell RNA - SCLC-21H [nTPM]":"5414.7","Cell RNA - SH-SY5Y [nTPM]":"7189.1","Cell RNA - SiHa [nTPM]":"4466.7","Cell RNA - SK-BR-3 [nTPM]":"17018.9","Cell RNA - SK-MEL-30 [nTPM]":"8305.7","Cell RNA - SuSa [nTPM]":"13626.1","Cell RNA - T-47d [nTPM]":"9809.7","Cell RNA - THP-1 [nTPM]":"17703.3","Cell RNA - TIME [nTPM]":"15637.8","Cell RNA - U-138 MG [nTPM]":"12617.8","Cell RNA - U-2 OS [nTPM]":"8438.9","Cell RNA - U-2197 [nTPM]":"12565.9","Cell RNA - U-251 MG [nTPM]":"6642.1","Cell RNA - U-266\/70 [nTPM]":"4951.2","Cell RNA - U-266\/84 [nTPM]":"5072.9","Cell RNA - U-698 [nTPM]":"3542.6","Cell RNA - U-87 MG [nTPM]":"6235.7","Cell RNA - U-937 [nTPM]":"13711.8","Cell RNA - WM-115 [nTPM]":"6294.4","Blood RNA - basophil [nTPM]":"5305.8","Blood RNA - classical monocyte [nTPM]":"9759.2","Blood RNA - eosinophil [nTPM]":"3824.6","Blood RNA - gdT-cell [nTPM]":"3085.1","Blood RNA - intermediate monocyte [nTPM]":"4907.9","Blood RNA - MAIT T-cell [nTPM]":"3420.5","Blood RNA - memory B-cell [nTPM]":"5374.6","Blood RNA - memory CD4 T-cell [nTPM]":"3047.3","Blood RNA - memory CD8 T-cell [nTPM]":"3425.6","Blood RNA - myeloid DC [nTPM]":"3444.6","Blood RNA - naive B-cell [nTPM]":"5567.3","Blood RNA - naive CD4 T-cell [nTPM]":"3080.8","Blood RNA - naive CD8 T-cell [nTPM]":"3911.2","Blood RNA - neutrophil [nTPM]":"1900.4","Blood RNA - NK-cell [nTPM]":"3759.1","Blood RNA - non-classical monocyte [nTPM]":"5775.1","Blood RNA - plasmacytoid DC [nTPM]":"4847.5","Blood RNA - T-reg [nTPM]":"2947.7","Blood RNA - total PBMC [nTPM]":"3929.0","Brain RNA - amygdala [nTPM]":"171347.0","Brain RNA - basal ganglia [nTPM]":"151652.8","Brain RNA - cerebellum [nTPM]":"132201.9","Brain RNA - cerebral cortex [nTPM]":"222644.8","Brain RNA - hippocampal formation [nTPM]":"151507.6","Brain RNA - hypothalamus [nTPM]":"137459.2","Brain RNA - medulla oblongata [nTPM]":"176794.8","Brain RNA - midbrain [nTPM]":"152802.2","Brain RNA - pons [nTPM]":"168465.9","Brain RNA - spinal cord [nTPM]":"138626.1","Brain RNA - thalamus [nTPM]":"176888.2","Brain RNA - white matter [nTPM]":"131378.4","Single Cell Type RNA - Adipocytes [nTPM]":"3924.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"2900.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3897.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"13282.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9769.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9713.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22625.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20857.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12033.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11841.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"107039.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"30777.5","Single Cell Type RNA - Club cells [nTPM]":"16135.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"19596.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"9288.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"40726.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"4255.4","Single Cell Type RNA - Ductal cells [nTPM]":"7191.4","Single Cell Type RNA - Early spermatids [nTPM]":"1555.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13044.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9033.9","Single Cell Type RNA - Endothelial cells [nTPM]":"7847.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7514.7","Single Cell Type RNA - Erythroid cells [nTPM]":"45610.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5089.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6305.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19235.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25645.6","Single Cell Type RNA - granulocytes [nTPM]":"3832.6","Single Cell Type RNA - Granulosa cells [nTPM]":"20400.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25951.4","Single Cell Type RNA - Hepatocytes [nTPM]":"59794.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24302.1","Single Cell Type RNA - Ionocytes [nTPM]":"19071.0","Single Cell Type RNA - Kupffer cells [nTPM]":"45533.4","Single Cell Type RNA - Langerhans cells [nTPM]":"7744.0","Single Cell Type RNA - Late spermatids [nTPM]":"7398.4","Single Cell Type RNA - Leydig cells [nTPM]":"11696.4","Single Cell Type RNA - Macrophages [nTPM]":"12124.7","Single Cell Type RNA - Melanocytes [nTPM]":"6894.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"15180.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"8901.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6410.5","Single Cell Type RNA - Paneth cells [nTPM]":"23865.9","Single Cell Type RNA - Peritubular cells [nTPM]":"8490.1","Single Cell Type RNA - Plasma cells [nTPM]":"13829.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9441.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"98329.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33652.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10474.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13614.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11019.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9403.5","Single Cell Type RNA - Spermatocytes [nTPM]":"12096.5","Single Cell Type RNA - Spermatogonia [nTPM]":"14338.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27110.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11475.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"11502.4","Single Cell Type RNA - Theca cells [nTPM]":"15179.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27138.6","Single Cell Type RNA - Urothelial cells [nTPM]":"21770.7"},{"Gene":"MT-CO3","Gene synonym":["CO3","COIII","COX3","MTCO3"],"Ensembl":"ENSG00000198938","Gene description":"Mitochondrially encoded cytochrome c oxidase III","Uniprot":["P00414"],"Chromosome":"MT","Position":"9207-9990","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Leber hereditary optic neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"189825.4","heart muscle":"231090.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"98114.9","Proximal enterocytes":"47697.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"47821.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042788"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042788":"AB_10793985"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.01e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"27612.7","Tissue RNA - adrenal gland [nTPM]":"53681.0","Tissue RNA - amygdala [nTPM]":"106768.6","Tissue RNA - appendix [nTPM]":"6403.7","Tissue RNA - basal ganglia [nTPM]":"100201.0","Tissue RNA - bone marrow [nTPM]":"11914.6","Tissue RNA - breast [nTPM]":"26962.2","Tissue RNA - cerebellum [nTPM]":"92217.9","Tissue RNA - cerebral cortex [nTPM]":"189825.4","Tissue RNA - cervix [nTPM]":"9972.2","Tissue RNA - choroid plexus [nTPM]":"122787.3","Tissue RNA - colon [nTPM]":"41553.8","Tissue RNA - duodenum [nTPM]":"21299.6","Tissue RNA - endometrium 1 [nTPM]":"10118.8","Tissue RNA - epididymis [nTPM]":"12166.4","Tissue RNA - esophagus [nTPM]":"23137.6","Tissue RNA - fallopian tube [nTPM]":"10414.1","Tissue RNA - gallbladder [nTPM]":"8134.8","Tissue RNA - heart muscle [nTPM]":"231090.6","Tissue RNA - hippocampal formation [nTPM]":"101700.1","Tissue RNA - hypothalamus [nTPM]":"98402.0","Tissue RNA - kidney [nTPM]":"135745.7","Tissue RNA - liver [nTPM]":"93934.0","Tissue RNA - lung [nTPM]":"11738.0","Tissue RNA - lymph node [nTPM]":"7309.6","Tissue RNA - medulla oblongata [nTPM]":"111323.1","Tissue RNA - midbrain [nTPM]":"103274.0","Tissue RNA - ovary [nTPM]":"9356.4","Tissue RNA - pancreas [nTPM]":"21307.1","Tissue RNA - parathyroid gland [nTPM]":"30833.6","Tissue RNA - pituitary gland [nTPM]":"18098.1","Tissue RNA - placenta [nTPM]":"9332.4","Tissue RNA - pons [nTPM]":"106050.0","Tissue RNA - prostate [nTPM]":"25270.8","Tissue RNA - rectum [nTPM]":"25404.7","Tissue RNA - retina [nTPM]":"14193.4","Tissue RNA - salivary gland [nTPM]":"21229.0","Tissue RNA - seminal vesicle [nTPM]":"16620.0","Tissue RNA - skeletal muscle [nTPM]":"98348.0","Tissue RNA - skin 1 [nTPM]":"28350.1","Tissue RNA - small intestine [nTPM]":"31017.2","Tissue RNA - smooth muscle [nTPM]":"10682.4","Tissue RNA - spinal cord [nTPM]":"91790.3","Tissue RNA - spleen [nTPM]":"14201.4","Tissue RNA - stomach 1 [nTPM]":"41772.3","Tissue RNA - testis [nTPM]":"19009.4","Tissue RNA - thalamus [nTPM]":"106894.6","Tissue RNA - thymus [nTPM]":"5959.0","Tissue RNA - thyroid gland [nTPM]":"20136.7","Tissue RNA - tongue [nTPM]":"138793.4","Tissue RNA - tonsil [nTPM]":"9366.6","Tissue RNA - urinary bladder [nTPM]":"19763.5","Tissue RNA - vagina [nTPM]":"13535.9","Tissue RNA - white matter [nTPM]":"91700.3","Cell RNA - A-431 [nTPM]":"6374.2","Cell RNA - A549 [nTPM]":"7329.2","Cell RNA - AF22 [nTPM]":"11033.5","Cell RNA - AN3-CA [nTPM]":"15732.2","Cell RNA - ASC diff [nTPM]":"21484.7","Cell RNA - ASC TERT1 [nTPM]":"8772.8","Cell RNA - BEWO [nTPM]":"6020.3","Cell RNA - BJ [nTPM]":"8032.3","Cell RNA - BJ hTERT+ [nTPM]":"4753.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3111.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4736.6","Cell RNA - CACO-2 [nTPM]":"9884.1","Cell RNA - CAPAN-2 [nTPM]":"9176.0","Cell RNA - Daudi [nTPM]":"14020.9","Cell RNA - EFO-21 [nTPM]":"3392.6","Cell RNA - fHDF\/TERT166 [nTPM]":"6719.8","Cell RNA - GAMG [nTPM]":"3380.0","Cell RNA - HaCaT [nTPM]":"16891.6","Cell RNA - HAP1 [nTPM]":"1769.9","Cell RNA - HBEC3-KT [nTPM]":"9653.6","Cell RNA - HBF TERT88 [nTPM]":"5455.7","Cell RNA - HDLM-2 [nTPM]":"4794.4","Cell RNA - HEK 293 [nTPM]":"7644.1","Cell RNA - HEL [nTPM]":"7478.3","Cell RNA - HeLa [nTPM]":"47821.5","Cell RNA - Hep G2 [nTPM]":"16704.0","Cell RNA - HHSteC [nTPM]":"4327.8","Cell RNA - HL-60 [nTPM]":"4505.2","Cell RNA - HMC-1 [nTPM]":"9419.7","Cell RNA - HSkMC [nTPM]":"8504.4","Cell RNA - hTCEpi [nTPM]":"13400.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3422.1","Cell RNA - hTERT-HME1 [nTPM]":"5046.7","Cell RNA - hTERT-RPE1 [nTPM]":"10915.4","Cell RNA - HUVEC TERT2 [nTPM]":"5848.3","Cell RNA - JURKAT [nTPM]":"7900.3","Cell RNA - K-562 [nTPM]":"6047.2","Cell RNA - Karpas-707 [nTPM]":"13759.0","Cell RNA - LHCN-M2 [nTPM]":"10367.7","Cell RNA - MCF7 [nTPM]":"12916.5","Cell RNA - MOLT-4 [nTPM]":"4589.9","Cell RNA - NB-4 [nTPM]":"25941.9","Cell RNA - NTERA-2 [nTPM]":"2461.0","Cell RNA - OE19 [nTPM]":"9979.3","Cell RNA - PC-3 [nTPM]":"5226.1","Cell RNA - REH [nTPM]":"4852.9","Cell RNA - RH-30 [nTPM]":"3482.9","Cell RNA - RPMI-8226 [nTPM]":"10181.9","Cell RNA - RPTEC TERT1 [nTPM]":"19232.2","Cell RNA - RT4 [nTPM]":"10970.2","Cell RNA - SCLC-21H [nTPM]":"4917.9","Cell RNA - SH-SY5Y [nTPM]":"6797.0","Cell RNA - SiHa [nTPM]":"3741.8","Cell RNA - SK-BR-3 [nTPM]":"4032.3","Cell RNA - SK-MEL-30 [nTPM]":"8135.9","Cell RNA - SuSa [nTPM]":"15244.2","Cell RNA - T-47d [nTPM]":"8471.0","Cell RNA - THP-1 [nTPM]":"19585.6","Cell RNA - TIME [nTPM]":"9432.2","Cell RNA - U-138 MG [nTPM]":"5152.8","Cell RNA - U-2 OS [nTPM]":"8782.1","Cell RNA - U-2197 [nTPM]":"9756.5","Cell RNA - U-251 MG [nTPM]":"5388.8","Cell RNA - U-266\/70 [nTPM]":"5622.3","Cell RNA - U-266\/84 [nTPM]":"3881.6","Cell RNA - U-698 [nTPM]":"8183.5","Cell RNA - U-87 MG [nTPM]":"5151.5","Cell RNA - U-937 [nTPM]":"14362.6","Cell RNA - WM-115 [nTPM]":"3475.8","Blood RNA - basophil [nTPM]":"2863.0","Blood RNA - classical monocyte [nTPM]":"4714.1","Blood RNA - eosinophil [nTPM]":"2004.7","Blood RNA - gdT-cell [nTPM]":"1562.3","Blood RNA - intermediate monocyte [nTPM]":"1885.5","Blood RNA - MAIT T-cell [nTPM]":"1896.8","Blood RNA - memory B-cell [nTPM]":"2933.1","Blood RNA - memory CD4 T-cell [nTPM]":"1703.2","Blood RNA - memory CD8 T-cell [nTPM]":"1823.0","Blood RNA - myeloid DC [nTPM]":"1927.4","Blood RNA - naive B-cell [nTPM]":"3253.5","Blood RNA - naive CD4 T-cell [nTPM]":"2137.7","Blood RNA - naive CD8 T-cell [nTPM]":"2759.1","Blood RNA - neutrophil [nTPM]":"3629.6","Blood RNA - NK-cell [nTPM]":"2089.5","Blood RNA - non-classical monocyte [nTPM]":"1920.3","Blood RNA - plasmacytoid DC [nTPM]":"1612.4","Blood RNA - T-reg [nTPM]":"1186.9","Blood RNA - total PBMC [nTPM]":"2432.3","Brain RNA - amygdala [nTPM]":"106768.6","Brain RNA - basal ganglia [nTPM]":"100201.0","Brain RNA - cerebellum [nTPM]":"92217.9","Brain RNA - cerebral cortex [nTPM]":"189825.4","Brain RNA - hippocampal formation [nTPM]":"101700.1","Brain RNA - hypothalamus [nTPM]":"98402.0","Brain RNA - medulla oblongata [nTPM]":"111323.1","Brain RNA - midbrain [nTPM]":"103274.0","Brain RNA - pons [nTPM]":"106050.0","Brain RNA - spinal cord [nTPM]":"91790.3","Brain RNA - thalamus [nTPM]":"106894.6","Brain RNA - white matter [nTPM]":"91700.3","Single Cell Type RNA - Adipocytes [nTPM]":"2817.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1910.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2767.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"9010.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8343.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9724.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21550.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14394.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8643.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8027.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"98114.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"20354.3","Single Cell Type RNA - Club cells [nTPM]":"11786.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16547.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"5698.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"25285.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"4368.9","Single Cell Type RNA - Ductal cells [nTPM]":"5152.0","Single Cell Type RNA - Early spermatids [nTPM]":"1929.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10274.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6922.4","Single Cell Type RNA - Endothelial cells [nTPM]":"7282.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6805.3","Single Cell Type RNA - Erythroid cells [nTPM]":"29321.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6670.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5902.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8605.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22503.2","Single Cell Type RNA - granulocytes [nTPM]":"2090.9","Single Cell Type RNA - Granulosa cells [nTPM]":"20302.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15810.3","Single Cell Type RNA - Hepatocytes [nTPM]":"44494.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19209.5","Single Cell Type RNA - Ionocytes [nTPM]":"11157.0","Single Cell Type RNA - Kupffer cells [nTPM]":"28166.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5603.1","Single Cell Type RNA - Late spermatids [nTPM]":"9286.2","Single Cell Type RNA - Leydig cells [nTPM]":"11579.8","Single Cell Type RNA - Macrophages [nTPM]":"7637.7","Single Cell Type RNA - Melanocytes [nTPM]":"5553.1","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"9746.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"6001.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5901.3","Single Cell Type RNA - Paneth cells [nTPM]":"16542.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7809.0","Single Cell Type RNA - Plasma cells [nTPM]":"8204.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6813.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47697.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33390.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6427.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"12142.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15068.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7967.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11927.7","Single Cell Type RNA - Spermatogonia [nTPM]":"12469.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17772.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8480.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"7584.6","Single Cell Type RNA - Theca cells [nTPM]":"21335.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22667.3","Single Cell Type RNA - Urothelial cells [nTPM]":"15127.4"},{"Gene":"MT-CYB","Gene synonym":["COB","CYTB","MTCYB","UQCR3"],"Ensembl":"ENSG00000198727","Gene description":"Mitochondrially encoded cytochrome b","Uniprot":["P00156"],"Chromosome":"MT","Position":"14747-15887","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Cataract","Deafness","Disease variant","Leber hereditary optic neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"130283.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"87067.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"14365.7","HeLa":"18945.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032215","HPA068400","HPA074796"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB032215":"AB_2261378","HPA068400":"AB_2685982","HPA074796":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.96e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"17885.7","Tissue RNA - adrenal gland [nTPM]":"25075.8","Tissue RNA - amygdala [nTPM]":"39972.4","Tissue RNA - appendix [nTPM]":"2636.6","Tissue RNA - basal ganglia [nTPM]":"41108.8","Tissue RNA - bone marrow [nTPM]":"2926.5","Tissue RNA - breast [nTPM]":"15122.5","Tissue RNA - cerebellum [nTPM]":"36592.4","Tissue RNA - cerebral cortex [nTPM]":"54341.4","Tissue RNA - cervix [nTPM]":"6621.5","Tissue RNA - choroid plexus [nTPM]":"47885.4","Tissue RNA - colon [nTPM]":"19364.4","Tissue RNA - duodenum [nTPM]":"8941.2","Tissue RNA - endometrium 1 [nTPM]":"7119.4","Tissue RNA - epididymis [nTPM]":"6555.4","Tissue RNA - esophagus [nTPM]":"10592.2","Tissue RNA - fallopian tube [nTPM]":"7498.6","Tissue RNA - gallbladder [nTPM]":"3433.7","Tissue RNA - heart muscle [nTPM]":"130283.4","Tissue RNA - hippocampal formation [nTPM]":"39044.7","Tissue RNA - hypothalamus [nTPM]":"39534.1","Tissue RNA - kidney [nTPM]":"60620.7","Tissue RNA - liver [nTPM]":"59133.6","Tissue RNA - lung [nTPM]":"6549.1","Tissue RNA - lymph node [nTPM]":"2529.8","Tissue RNA - medulla oblongata [nTPM]":"46506.6","Tissue RNA - midbrain [nTPM]":"40032.7","Tissue RNA - ovary [nTPM]":"6068.7","Tissue RNA - pancreas [nTPM]":"15418.7","Tissue RNA - parathyroid gland [nTPM]":"9106.2","Tissue RNA - pituitary gland [nTPM]":"11552.0","Tissue RNA - placenta [nTPM]":"5320.4","Tissue RNA - pons [nTPM]":"42841.1","Tissue RNA - prostate [nTPM]":"15142.5","Tissue RNA - rectum [nTPM]":"8793.2","Tissue RNA - retina [nTPM]":"8513.5","Tissue RNA - salivary gland [nTPM]":"12205.1","Tissue RNA - seminal vesicle [nTPM]":"7331.2","Tissue RNA - skeletal muscle [nTPM]":"52625.7","Tissue RNA - skin 1 [nTPM]":"13392.0","Tissue RNA - small intestine [nTPM]":"17520.7","Tissue RNA - smooth muscle [nTPM]":"5804.8","Tissue RNA - spinal cord [nTPM]":"34579.6","Tissue RNA - spleen [nTPM]":"7362.7","Tissue RNA - stomach 1 [nTPM]":"25263.2","Tissue RNA - testis [nTPM]":"7372.2","Tissue RNA - thalamus [nTPM]":"41908.6","Tissue RNA - thymus [nTPM]":"1737.2","Tissue RNA - thyroid gland [nTPM]":"9758.2","Tissue RNA - tongue [nTPM]":"63751.5","Tissue RNA - tonsil [nTPM]":"3582.0","Tissue RNA - urinary bladder [nTPM]":"12844.4","Tissue RNA - vagina [nTPM]":"7620.0","Tissue RNA - white matter [nTPM]":"35340.5","Cell RNA - A-431 [nTPM]":"2322.4","Cell RNA - A549 [nTPM]":"3039.1","Cell RNA - AF22 [nTPM]":"3687.6","Cell RNA - AN3-CA [nTPM]":"3950.3","Cell RNA - ASC diff [nTPM]":"14365.7","Cell RNA - ASC TERT1 [nTPM]":"2287.8","Cell RNA - BEWO [nTPM]":"2963.8","Cell RNA - BJ [nTPM]":"2587.3","Cell RNA - BJ hTERT+ [nTPM]":"1076.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"668.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1136.3","Cell RNA - CACO-2 [nTPM]":"3013.8","Cell RNA - CAPAN-2 [nTPM]":"4943.2","Cell RNA - Daudi [nTPM]":"5840.7","Cell RNA - EFO-21 [nTPM]":"1240.7","Cell RNA - fHDF\/TERT166 [nTPM]":"3087.3","Cell RNA - GAMG [nTPM]":"794.6","Cell RNA - HaCaT [nTPM]":"7063.3","Cell RNA - HAP1 [nTPM]":"556.2","Cell RNA - HBEC3-KT [nTPM]":"3180.7","Cell RNA - HBF TERT88 [nTPM]":"1613.0","Cell RNA - HDLM-2 [nTPM]":"2880.4","Cell RNA - HEK 293 [nTPM]":"2458.9","Cell RNA - HEL [nTPM]":"3277.0","Cell RNA - HeLa [nTPM]":"18945.0","Cell RNA - Hep G2 [nTPM]":"5461.7","Cell RNA - HHSteC [nTPM]":"2697.8","Cell RNA - HL-60 [nTPM]":"1862.5","Cell RNA - HMC-1 [nTPM]":"3828.3","Cell RNA - HSkMC [nTPM]":"4981.3","Cell RNA - hTCEpi [nTPM]":"4631.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1257.6","Cell RNA - hTERT-HME1 [nTPM]":"2679.7","Cell RNA - hTERT-RPE1 [nTPM]":"4457.1","Cell RNA - HUVEC TERT2 [nTPM]":"1715.5","Cell RNA - JURKAT [nTPM]":"2341.4","Cell RNA - K-562 [nTPM]":"1709.0","Cell RNA - Karpas-707 [nTPM]":"3565.6","Cell RNA - LHCN-M2 [nTPM]":"3417.2","Cell RNA - MCF7 [nTPM]":"6354.8","Cell RNA - MOLT-4 [nTPM]":"1735.3","Cell RNA - NB-4 [nTPM]":"3789.4","Cell RNA - NTERA-2 [nTPM]":"824.1","Cell RNA - OE19 [nTPM]":"2230.7","Cell RNA - PC-3 [nTPM]":"2036.7","Cell RNA - REH [nTPM]":"2028.2","Cell RNA - RH-30 [nTPM]":"1449.8","Cell RNA - RPMI-8226 [nTPM]":"3681.4","Cell RNA - RPTEC TERT1 [nTPM]":"5134.1","Cell RNA - RT4 [nTPM]":"5275.9","Cell RNA - SCLC-21H [nTPM]":"1308.0","Cell RNA - SH-SY5Y [nTPM]":"2302.7","Cell RNA - SiHa [nTPM]":"1802.1","Cell RNA - SK-BR-3 [nTPM]":"3352.1","Cell RNA - SK-MEL-30 [nTPM]":"2587.4","Cell RNA - SuSa [nTPM]":"5497.2","Cell RNA - T-47d [nTPM]":"4911.1","Cell RNA - THP-1 [nTPM]":"6332.5","Cell RNA - TIME [nTPM]":"5398.3","Cell RNA - U-138 MG [nTPM]":"2302.7","Cell RNA - U-2 OS [nTPM]":"2984.2","Cell RNA - U-2197 [nTPM]":"4256.3","Cell RNA - U-251 MG [nTPM]":"2037.2","Cell RNA - U-266\/70 [nTPM]":"972.6","Cell RNA - U-266\/84 [nTPM]":"1390.1","Cell RNA - U-698 [nTPM]":"2557.4","Cell RNA - U-87 MG [nTPM]":"1385.7","Cell RNA - U-937 [nTPM]":"2822.6","Cell RNA - WM-115 [nTPM]":"1485.0","Blood RNA - basophil [nTPM]":"8811.6","Blood RNA - classical monocyte [nTPM]":"3750.4","Blood RNA - eosinophil [nTPM]":"4806.7","Blood RNA - gdT-cell [nTPM]":"1834.1","Blood RNA - intermediate monocyte [nTPM]":"1738.1","Blood RNA - MAIT T-cell [nTPM]":"2355.1","Blood RNA - memory B-cell [nTPM]":"2806.2","Blood RNA - memory CD4 T-cell [nTPM]":"2123.9","Blood RNA - memory CD8 T-cell [nTPM]":"2376.2","Blood RNA - myeloid DC [nTPM]":"1485.5","Blood RNA - naive B-cell [nTPM]":"3034.9","Blood RNA - naive CD4 T-cell [nTPM]":"2241.0","Blood RNA - naive CD8 T-cell [nTPM]":"2781.9","Blood RNA - neutrophil [nTPM]":"2755.9","Blood RNA - NK-cell [nTPM]":"1680.5","Blood RNA - non-classical monocyte [nTPM]":"1944.8","Blood RNA - plasmacytoid DC [nTPM]":"1468.0","Blood RNA - T-reg [nTPM]":"1511.0","Blood RNA - total PBMC [nTPM]":"1612.6","Brain RNA - amygdala [nTPM]":"39972.4","Brain RNA - basal ganglia [nTPM]":"41108.8","Brain RNA - cerebellum [nTPM]":"36592.4","Brain RNA - cerebral cortex [nTPM]":"54341.4","Brain RNA - hippocampal formation [nTPM]":"39044.7","Brain RNA - hypothalamus [nTPM]":"39534.1","Brain RNA - medulla oblongata [nTPM]":"46506.6","Brain RNA - midbrain [nTPM]":"40032.7","Brain RNA - pons [nTPM]":"42841.1","Brain RNA - spinal cord [nTPM]":"34579.6","Brain RNA - thalamus [nTPM]":"41908.6","Brain RNA - white matter [nTPM]":"35340.5","Single Cell Type RNA - Adipocytes [nTPM]":"3091.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1185.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1390.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5710.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3319.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7605.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9945.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8512.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4026.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5510.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"87067.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"11564.1","Single Cell Type RNA - Club cells [nTPM]":"5338.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7470.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"3723.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"10971.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"2163.9","Single Cell Type RNA - Ductal cells [nTPM]":"2555.0","Single Cell Type RNA - Early spermatids [nTPM]":"789.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9063.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5550.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5673.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2863.2","Single Cell Type RNA - Erythroid cells [nTPM]":"16130.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3523.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4692.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4895.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15794.2","Single Cell Type RNA - granulocytes [nTPM]":"1889.0","Single Cell Type RNA - Granulosa cells [nTPM]":"16261.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9871.2","Single Cell Type RNA - Hepatocytes [nTPM]":"17132.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9502.4","Single Cell Type RNA - Ionocytes [nTPM]":"5486.9","Single Cell Type RNA - Kupffer cells [nTPM]":"14290.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2254.1","Single Cell Type RNA - Late spermatids [nTPM]":"3983.1","Single Cell Type RNA - Leydig cells [nTPM]":"7943.2","Single Cell Type RNA - Macrophages [nTPM]":"4269.6","Single Cell Type RNA - Melanocytes [nTPM]":"2612.9","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4118.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2612.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2977.1","Single Cell Type RNA - Paneth cells [nTPM]":"8823.6","Single Cell Type RNA - Peritubular cells [nTPM]":"5402.0","Single Cell Type RNA - Plasma cells [nTPM]":"5725.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4425.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25108.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14736.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4210.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"5798.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9579.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5914.9","Single Cell Type RNA - Spermatocytes [nTPM]":"4807.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4136.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9142.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3422.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"5502.2","Single Cell Type RNA - Theca cells [nTPM]":"11093.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10319.6","Single Cell Type RNA - Urothelial cells [nTPM]":"9796.7"},{"Gene":"MT-ND1","Gene synonym":["MTND1","NAD1","ND1"],"Ensembl":"ENSG00000198888","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1","Uniprot":["P03886"],"Chromosome":"MT","Position":"3307-4262","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Alzheimer disease","Amyloidosis","Diabetes mellitus","Disease variant","Epilepsy","FDA approved drug targets","Leber hereditary optic neuropathy","MELAS syndrome","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"111350.7","heart muscle":"127951.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"101184.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"9432.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"9432.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"28480.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033779","HPA066847"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033779":"AB_2149736","HPA066847":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.63e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"19099.4","Tissue RNA - adrenal gland [nTPM]":"24937.1","Tissue RNA - amygdala [nTPM]":"77977.0","Tissue RNA - appendix [nTPM]":"2682.9","Tissue RNA - basal ganglia [nTPM]":"79000.3","Tissue RNA - bone marrow [nTPM]":"3456.4","Tissue RNA - breast [nTPM]":"17901.1","Tissue RNA - cerebellum [nTPM]":"73833.1","Tissue RNA - cerebral cortex [nTPM]":"111350.7","Tissue RNA - cervix [nTPM]":"4652.6","Tissue RNA - choroid plexus [nTPM]":"82243.3","Tissue RNA - colon [nTPM]":"19464.4","Tissue RNA - duodenum [nTPM]":"6416.3","Tissue RNA - endometrium 1 [nTPM]":"5929.7","Tissue RNA - epididymis [nTPM]":"6428.9","Tissue RNA - esophagus [nTPM]":"8365.1","Tissue RNA - fallopian tube [nTPM]":"6119.1","Tissue RNA - gallbladder [nTPM]":"2846.9","Tissue RNA - heart muscle [nTPM]":"127951.9","Tissue RNA - hippocampal formation [nTPM]":"74131.5","Tissue RNA - hypothalamus [nTPM]":"81543.6","Tissue RNA - kidney [nTPM]":"47946.3","Tissue RNA - liver [nTPM]":"45024.8","Tissue RNA - lung [nTPM]":"7877.3","Tissue RNA - lymph node [nTPM]":"2245.9","Tissue RNA - medulla oblongata [nTPM]":"84675.5","Tissue RNA - midbrain [nTPM]":"84925.4","Tissue RNA - ovary [nTPM]":"4636.3","Tissue RNA - pancreas [nTPM]":"15523.0","Tissue RNA - parathyroid gland [nTPM]":"12519.5","Tissue RNA - pituitary gland [nTPM]":"7993.9","Tissue RNA - placenta [nTPM]":"5163.4","Tissue RNA - pons [nTPM]":"88069.3","Tissue RNA - prostate [nTPM]":"11358.6","Tissue RNA - rectum [nTPM]":"8792.2","Tissue RNA - retina [nTPM]":"6455.8","Tissue RNA - salivary gland [nTPM]":"11429.4","Tissue RNA - seminal vesicle [nTPM]":"7047.3","Tissue RNA - skeletal muscle [nTPM]":"69102.4","Tissue RNA - skin 1 [nTPM]":"14504.0","Tissue RNA - small intestine [nTPM]":"16935.3","Tissue RNA - smooth muscle [nTPM]":"3849.2","Tissue RNA - spinal cord [nTPM]":"68588.4","Tissue RNA - spleen [nTPM]":"8228.4","Tissue RNA - stomach 1 [nTPM]":"26033.5","Tissue RNA - testis [nTPM]":"12223.4","Tissue RNA - thalamus [nTPM]":"81883.1","Tissue RNA - thymus [nTPM]":"2158.8","Tissue RNA - thyroid gland [nTPM]":"7231.1","Tissue RNA - tongue [nTPM]":"61460.4","Tissue RNA - tonsil [nTPM]":"2986.2","Tissue RNA - urinary bladder [nTPM]":"10333.3","Tissue RNA - vagina [nTPM]":"5443.7","Tissue RNA - white matter [nTPM]":"72626.3","Cell RNA - A-431 [nTPM]":"3533.6","Cell RNA - A549 [nTPM]":"3499.2","Cell RNA - AF22 [nTPM]":"2812.3","Cell RNA - AN3-CA [nTPM]":"2571.1","Cell RNA - ASC diff [nTPM]":"10434.4","Cell RNA - ASC TERT1 [nTPM]":"1879.8","Cell RNA - BEWO [nTPM]":"3604.8","Cell RNA - BJ [nTPM]":"2946.1","Cell RNA - BJ hTERT+ [nTPM]":"872.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"805.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"835.0","Cell RNA - CACO-2 [nTPM]":"6132.0","Cell RNA - CAPAN-2 [nTPM]":"3710.1","Cell RNA - Daudi [nTPM]":"4259.8","Cell RNA - EFO-21 [nTPM]":"1831.7","Cell RNA - fHDF\/TERT166 [nTPM]":"2239.3","Cell RNA - GAMG [nTPM]":"810.9","Cell RNA - HaCaT [nTPM]":"2285.7","Cell RNA - HAP1 [nTPM]":"316.3","Cell RNA - HBEC3-KT [nTPM]":"1774.7","Cell RNA - HBF TERT88 [nTPM]":"1592.0","Cell RNA - HDLM-2 [nTPM]":"3064.7","Cell RNA - HEK 293 [nTPM]":"2432.6","Cell RNA - HEL [nTPM]":"4755.7","Cell RNA - HeLa [nTPM]":"28480.4","Cell RNA - Hep G2 [nTPM]":"8841.6","Cell RNA - HHSteC [nTPM]":"2231.9","Cell RNA - HL-60 [nTPM]":"2279.1","Cell RNA - HMC-1 [nTPM]":"4495.2","Cell RNA - HSkMC [nTPM]":"4494.5","Cell RNA - hTCEpi [nTPM]":"4734.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1241.1","Cell RNA - hTERT-HME1 [nTPM]":"1773.2","Cell RNA - hTERT-RPE1 [nTPM]":"3240.7","Cell RNA - HUVEC TERT2 [nTPM]":"877.2","Cell RNA - JURKAT [nTPM]":"1226.5","Cell RNA - K-562 [nTPM]":"2235.4","Cell RNA - Karpas-707 [nTPM]":"2580.5","Cell RNA - LHCN-M2 [nTPM]":"2400.4","Cell RNA - MCF7 [nTPM]":"4813.7","Cell RNA - MOLT-4 [nTPM]":"1841.1","Cell RNA - NB-4 [nTPM]":"9325.6","Cell RNA - NTERA-2 [nTPM]":"757.8","Cell RNA - OE19 [nTPM]":"2191.3","Cell RNA - PC-3 [nTPM]":"2603.6","Cell RNA - REH [nTPM]":"1916.7","Cell RNA - RH-30 [nTPM]":"1277.6","Cell RNA - RPMI-8226 [nTPM]":"2295.7","Cell RNA - RPTEC TERT1 [nTPM]":"4312.3","Cell RNA - RT4 [nTPM]":"5574.2","Cell RNA - SCLC-21H [nTPM]":"1165.0","Cell RNA - SH-SY5Y [nTPM]":"1844.2","Cell RNA - SiHa [nTPM]":"1632.5","Cell RNA - SK-BR-3 [nTPM]":"2572.1","Cell RNA - SK-MEL-30 [nTPM]":"2943.6","Cell RNA - SuSa [nTPM]":"3403.7","Cell RNA - T-47d [nTPM]":"2306.2","Cell RNA - THP-1 [nTPM]":"7771.2","Cell RNA - TIME [nTPM]":"4632.1","Cell RNA - U-138 MG [nTPM]":"2652.3","Cell RNA - U-2 OS [nTPM]":"2396.0","Cell RNA - U-2197 [nTPM]":"3427.2","Cell RNA - U-251 MG [nTPM]":"2511.3","Cell RNA - U-266\/70 [nTPM]":"2841.3","Cell RNA - U-266\/84 [nTPM]":"1883.7","Cell RNA - U-698 [nTPM]":"2015.4","Cell RNA - U-87 MG [nTPM]":"1784.6","Cell RNA - U-937 [nTPM]":"3937.3","Cell RNA - WM-115 [nTPM]":"744.7","Blood RNA - basophil [nTPM]":"9432.2","Blood RNA - classical monocyte [nTPM]":"1265.2","Blood RNA - eosinophil [nTPM]":"2347.3","Blood RNA - gdT-cell [nTPM]":"512.4","Blood RNA - intermediate monocyte [nTPM]":"662.6","Blood RNA - MAIT T-cell [nTPM]":"732.0","Blood RNA - memory B-cell [nTPM]":"1155.4","Blood RNA - memory CD4 T-cell [nTPM]":"614.6","Blood RNA - memory CD8 T-cell [nTPM]":"683.5","Blood RNA - myeloid DC [nTPM]":"439.9","Blood RNA - naive B-cell [nTPM]":"1185.3","Blood RNA - naive CD4 T-cell [nTPM]":"800.8","Blood RNA - naive CD8 T-cell [nTPM]":"960.2","Blood RNA - neutrophil [nTPM]":"3270.7","Blood RNA - NK-cell [nTPM]":"759.6","Blood RNA - non-classical monocyte [nTPM]":"733.2","Blood RNA - plasmacytoid DC [nTPM]":"677.2","Blood RNA - T-reg [nTPM]":"480.0","Blood RNA - total PBMC [nTPM]":"507.7","Brain RNA - amygdala [nTPM]":"77977.0","Brain RNA - basal ganglia [nTPM]":"79000.3","Brain RNA - cerebellum [nTPM]":"73833.1","Brain RNA - cerebral cortex [nTPM]":"111350.7","Brain RNA - hippocampal formation [nTPM]":"74131.5","Brain RNA - hypothalamus [nTPM]":"81543.6","Brain RNA - medulla oblongata [nTPM]":"84675.5","Brain RNA - midbrain [nTPM]":"84925.4","Brain RNA - pons [nTPM]":"88069.3","Brain RNA - spinal cord [nTPM]":"68588.4","Brain RNA - thalamus [nTPM]":"81883.1","Brain RNA - white matter [nTPM]":"72626.3","Single Cell Type RNA - Adipocytes [nTPM]":"1754.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1352.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1511.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3159.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2265.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3355.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1632.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2928.1","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3174.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3513.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"101184.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"9771.1","Single Cell Type RNA - Club cells [nTPM]":"1985.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"4610.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2175.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"12456.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1033.1","Single Cell Type RNA - Ductal cells [nTPM]":"1511.9","Single Cell Type RNA - Early spermatids [nTPM]":"1087.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3160.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1985.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4881.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3135.6","Single Cell Type RNA - Erythroid cells [nTPM]":"8308.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3595.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2970.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2347.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5039.6","Single Cell Type RNA - granulocytes [nTPM]":"1402.2","Single Cell Type RNA - Granulosa cells [nTPM]":"7165.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7745.2","Single Cell Type RNA - Hepatocytes [nTPM]":"16276.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10835.1","Single Cell Type RNA - Ionocytes [nTPM]":"927.7","Single Cell Type RNA - Kupffer cells [nTPM]":"12435.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1651.4","Single Cell Type RNA - Late spermatids [nTPM]":"5233.2","Single Cell Type RNA - Leydig cells [nTPM]":"7049.5","Single Cell Type RNA - Macrophages [nTPM]":"2982.5","Single Cell Type RNA - Melanocytes [nTPM]":"1497.7","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4450.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2385.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2180.4","Single Cell Type RNA - Paneth cells [nTPM]":"8080.9","Single Cell Type RNA - Peritubular cells [nTPM]":"3546.9","Single Cell Type RNA - Plasma cells [nTPM]":"2046.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3735.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18353.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8183.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1760.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6409.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6534.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4075.7","Single Cell Type RNA - Spermatocytes [nTPM]":"4806.0","Single Cell Type RNA - Spermatogonia [nTPM]":"5071.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2061.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2073.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2839.0","Single Cell Type RNA - Theca cells [nTPM]":"4329.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10735.4","Single Cell Type RNA - Urothelial cells [nTPM]":"5236.0"},{"Gene":"MT-ND2","Gene synonym":["MTND2","NAD2","ND2"],"Ensembl":"ENSG00000198763","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2","Uniprot":["P03891"],"Chromosome":"MT","Position":"4470-5511","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Alzheimer disease","Amyloidosis","Disease variant","Leber hereditary optic neuropathy","Leigh syndrome","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"101525.8","heart muscle":"130517.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"77734.8","Proximal enterocytes":"33797.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"16754.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"16754.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"23544.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"25741.8","Tissue RNA - adrenal gland [nTPM]":"33190.5","Tissue RNA - amygdala [nTPM]":"71860.8","Tissue RNA - appendix [nTPM]":"2728.1","Tissue RNA - basal ganglia [nTPM]":"75185.8","Tissue RNA - bone marrow [nTPM]":"2871.9","Tissue RNA - breast [nTPM]":"21730.1","Tissue RNA - cerebellum [nTPM]":"67030.8","Tissue RNA - cerebral cortex [nTPM]":"101525.8","Tissue RNA - cervix [nTPM]":"7501.8","Tissue RNA - choroid plexus [nTPM]":"71811.2","Tissue RNA - colon [nTPM]":"22574.5","Tissue RNA - duodenum [nTPM]":"7339.4","Tissue RNA - endometrium 1 [nTPM]":"7298.5","Tissue RNA - epididymis [nTPM]":"8093.3","Tissue RNA - esophagus [nTPM]":"11090.4","Tissue RNA - fallopian tube [nTPM]":"9270.8","Tissue RNA - gallbladder [nTPM]":"2863.6","Tissue RNA - heart muscle [nTPM]":"130517.4","Tissue RNA - hippocampal formation [nTPM]":"67583.8","Tissue RNA - hypothalamus [nTPM]":"74656.1","Tissue RNA - kidney [nTPM]":"57055.4","Tissue RNA - liver [nTPM]":"53965.1","Tissue RNA - lung [nTPM]":"9461.4","Tissue RNA - lymph node [nTPM]":"2469.7","Tissue RNA - medulla oblongata [nTPM]":"81497.3","Tissue RNA - midbrain [nTPM]":"77858.3","Tissue RNA - ovary [nTPM]":"7800.1","Tissue RNA - pancreas [nTPM]":"20642.6","Tissue RNA - parathyroid gland [nTPM]":"9848.0","Tissue RNA - pituitary gland [nTPM]":"12388.5","Tissue RNA - placenta [nTPM]":"5446.8","Tissue RNA - pons [nTPM]":"84069.6","Tissue RNA - prostate [nTPM]":"17166.0","Tissue RNA - rectum [nTPM]":"8141.9","Tissue RNA - retina [nTPM]":"5436.2","Tissue RNA - salivary gland [nTPM]":"13468.5","Tissue RNA - seminal vesicle [nTPM]":"5444.8","Tissue RNA - skeletal muscle [nTPM]":"45903.7","Tissue RNA - skin 1 [nTPM]":"15500.0","Tissue RNA - small intestine [nTPM]":"20333.4","Tissue RNA - smooth muscle [nTPM]":"3554.4","Tissue RNA - spinal cord [nTPM]":"65578.7","Tissue RNA - spleen [nTPM]":"8952.9","Tissue RNA - stomach 1 [nTPM]":"31183.1","Tissue RNA - testis [nTPM]":"11451.9","Tissue RNA - thalamus [nTPM]":"75256.7","Tissue RNA - thymus [nTPM]":"2049.2","Tissue RNA - thyroid gland [nTPM]":"10704.5","Tissue RNA - tongue [nTPM]":"50400.1","Tissue RNA - tonsil [nTPM]":"2830.9","Tissue RNA - urinary bladder [nTPM]":"14131.4","Tissue RNA - vagina [nTPM]":"8428.2","Tissue RNA - white matter [nTPM]":"66998.7","Cell RNA - A-431 [nTPM]":"2964.9","Cell RNA - A549 [nTPM]":"3166.9","Cell RNA - AF22 [nTPM]":"2774.5","Cell RNA - AN3-CA [nTPM]":"4699.2","Cell RNA - ASC diff [nTPM]":"9795.6","Cell RNA - ASC TERT1 [nTPM]":"1730.7","Cell RNA - BEWO [nTPM]":"2618.5","Cell RNA - BJ [nTPM]":"2678.9","Cell RNA - BJ hTERT+ [nTPM]":"669.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"703.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"875.8","Cell RNA - CACO-2 [nTPM]":"4014.2","Cell RNA - CAPAN-2 [nTPM]":"3860.6","Cell RNA - Daudi [nTPM]":"4185.9","Cell RNA - EFO-21 [nTPM]":"2486.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1936.7","Cell RNA - GAMG [nTPM]":"1150.4","Cell RNA - HaCaT [nTPM]":"5147.5","Cell RNA - HAP1 [nTPM]":"444.4","Cell RNA - HBEC3-KT [nTPM]":"3349.6","Cell RNA - HBF TERT88 [nTPM]":"1504.2","Cell RNA - HDLM-2 [nTPM]":"3675.8","Cell RNA - HEK 293 [nTPM]":"2270.9","Cell RNA - HEL [nTPM]":"4845.1","Cell RNA - HeLa [nTPM]":"23544.1","Cell RNA - Hep G2 [nTPM]":"6585.1","Cell RNA - HHSteC [nTPM]":"1999.7","Cell RNA - HL-60 [nTPM]":"4760.9","Cell RNA - HMC-1 [nTPM]":"5392.4","Cell RNA - HSkMC [nTPM]":"2886.1","Cell RNA - hTCEpi [nTPM]":"5969.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1726.7","Cell RNA - hTERT-HME1 [nTPM]":"1692.0","Cell RNA - hTERT-RPE1 [nTPM]":"2488.5","Cell RNA - HUVEC TERT2 [nTPM]":"1049.4","Cell RNA - JURKAT [nTPM]":"2269.3","Cell RNA - K-562 [nTPM]":"3606.2","Cell RNA - Karpas-707 [nTPM]":"3978.3","Cell RNA - LHCN-M2 [nTPM]":"1701.5","Cell RNA - MCF7 [nTPM]":"3480.4","Cell RNA - MOLT-4 [nTPM]":"2711.2","Cell RNA - NB-4 [nTPM]":"7603.4","Cell RNA - NTERA-2 [nTPM]":"1396.2","Cell RNA - OE19 [nTPM]":"3068.2","Cell RNA - PC-3 [nTPM]":"2045.4","Cell RNA - REH [nTPM]":"2352.3","Cell RNA - RH-30 [nTPM]":"1554.8","Cell RNA - RPMI-8226 [nTPM]":"3525.9","Cell RNA - RPTEC TERT1 [nTPM]":"5071.4","Cell RNA - RT4 [nTPM]":"4465.8","Cell RNA - SCLC-21H [nTPM]":"1728.4","Cell RNA - SH-SY5Y [nTPM]":"2059.3","Cell RNA - SiHa [nTPM]":"1159.0","Cell RNA - SK-BR-3 [nTPM]":"3501.0","Cell RNA - SK-MEL-30 [nTPM]":"4372.7","Cell RNA - SuSa [nTPM]":"4402.7","Cell RNA - T-47d [nTPM]":"5412.1","Cell RNA - THP-1 [nTPM]":"5417.8","Cell RNA - TIME [nTPM]":"3333.0","Cell RNA - U-138 MG [nTPM]":"2606.6","Cell RNA - U-2 OS [nTPM]":"3230.5","Cell RNA - U-2197 [nTPM]":"3719.5","Cell RNA - U-251 MG [nTPM]":"3483.2","Cell RNA - U-266\/70 [nTPM]":"2577.9","Cell RNA - U-266\/84 [nTPM]":"2356.8","Cell RNA - U-698 [nTPM]":"3637.4","Cell RNA - U-87 MG [nTPM]":"1695.0","Cell RNA - U-937 [nTPM]":"4006.5","Cell RNA - WM-115 [nTPM]":"1196.1","Blood RNA - basophil [nTPM]":"16754.8","Blood RNA - classical monocyte [nTPM]":"1658.1","Blood RNA - eosinophil [nTPM]":"2709.0","Blood RNA - gdT-cell [nTPM]":"872.0","Blood RNA - intermediate monocyte [nTPM]":"1066.1","Blood RNA - MAIT T-cell [nTPM]":"1373.3","Blood RNA - memory B-cell [nTPM]":"1568.7","Blood RNA - memory CD4 T-cell [nTPM]":"1012.2","Blood RNA - memory CD8 T-cell [nTPM]":"1099.7","Blood RNA - myeloid DC [nTPM]":"632.5","Blood RNA - naive B-cell [nTPM]":"1625.8","Blood RNA - naive CD4 T-cell [nTPM]":"1212.2","Blood RNA - naive CD8 T-cell [nTPM]":"1558.3","Blood RNA - neutrophil [nTPM]":"2355.9","Blood RNA - NK-cell [nTPM]":"1158.8","Blood RNA - non-classical monocyte [nTPM]":"1341.7","Blood RNA - plasmacytoid DC [nTPM]":"1171.9","Blood RNA - T-reg [nTPM]":"716.1","Blood RNA - total PBMC [nTPM]":"804.2","Brain RNA - amygdala [nTPM]":"71860.8","Brain RNA - basal ganglia [nTPM]":"75185.8","Brain RNA - cerebellum [nTPM]":"67030.8","Brain RNA - cerebral cortex [nTPM]":"101525.8","Brain RNA - hippocampal formation [nTPM]":"67583.8","Brain RNA - hypothalamus [nTPM]":"74656.1","Brain RNA - medulla oblongata [nTPM]":"81497.3","Brain RNA - midbrain [nTPM]":"77858.3","Brain RNA - pons [nTPM]":"84069.6","Brain RNA - spinal cord [nTPM]":"65578.7","Brain RNA - thalamus [nTPM]":"75256.7","Brain RNA - white matter [nTPM]":"66998.7","Single Cell Type RNA - Adipocytes [nTPM]":"1855.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"919.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"759.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3886.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2666.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7962.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3116.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2155.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2560.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3948.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"77734.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"10211.5","Single Cell Type RNA - Club cells [nTPM]":"2425.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"6232.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2313.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"13115.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1807.8","Single Cell Type RNA - Ductal cells [nTPM]":"1793.7","Single Cell Type RNA - Early spermatids [nTPM]":"1314.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4100.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2322.6","Single Cell Type RNA - Endothelial cells [nTPM]":"4025.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3175.3","Single Cell Type RNA - Erythroid cells [nTPM]":"10585.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3677.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2629.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2366.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5225.2","Single Cell Type RNA - granulocytes [nTPM]":"1865.9","Single Cell Type RNA - Granulosa cells [nTPM]":"7033.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9394.0","Single Cell Type RNA - Hepatocytes [nTPM]":"19067.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10974.6","Single Cell Type RNA - Ionocytes [nTPM]":"1947.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14566.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1814.8","Single Cell Type RNA - Late spermatids [nTPM]":"6327.6","Single Cell Type RNA - Leydig cells [nTPM]":"9064.4","Single Cell Type RNA - Macrophages [nTPM]":"3148.2","Single Cell Type RNA - Melanocytes [nTPM]":"1657.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4768.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"3602.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2565.3","Single Cell Type RNA - Paneth cells [nTPM]":"9271.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4538.8","Single Cell Type RNA - Plasma cells [nTPM]":"1959.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4228.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33797.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12714.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3449.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"7283.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6341.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3547.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5465.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4872.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1826.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2455.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"3694.7","Single Cell Type RNA - Theca cells [nTPM]":"2538.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10272.4","Single Cell Type RNA - Urothelial cells [nTPM]":"7385.5"},{"Gene":"MT-ND4","Gene synonym":["LHON","MTND4","NAD4","ND4"],"Ensembl":"ENSG00000198886","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4","Uniprot":["P03905"],"Chromosome":"MT","Position":"10760-12137","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Dystonia","Leber hereditary optic neuropathy","MELAS syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"196536.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cardiomyocytes":"253563.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"13456.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"41594.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053928"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA053928":"AB_2682313"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"23701.9","Tissue RNA - adrenal gland [nTPM]":"43566.1","Tissue RNA - amygdala [nTPM]":"86386.5","Tissue RNA - appendix [nTPM]":"4193.8","Tissue RNA - basal ganglia [nTPM]":"83474.8","Tissue RNA - bone marrow [nTPM]":"3652.7","Tissue RNA - breast [nTPM]":"19363.5","Tissue RNA - cerebellum [nTPM]":"76852.9","Tissue RNA - cerebral cortex [nTPM]":"119139.4","Tissue RNA - cervix [nTPM]":"8711.6","Tissue RNA - choroid plexus [nTPM]":"100909.6","Tissue RNA - colon [nTPM]":"30312.4","Tissue RNA - duodenum [nTPM]":"11021.5","Tissue RNA - endometrium 1 [nTPM]":"10764.3","Tissue RNA - epididymis [nTPM]":"6795.9","Tissue RNA - esophagus [nTPM]":"15885.7","Tissue RNA - fallopian tube [nTPM]":"10624.6","Tissue RNA - gallbladder [nTPM]":"4622.9","Tissue RNA - heart muscle [nTPM]":"196536.0","Tissue RNA - hippocampal formation [nTPM]":"81116.7","Tissue RNA - hypothalamus [nTPM]":"85290.4","Tissue RNA - kidney [nTPM]":"76204.1","Tissue RNA - liver [nTPM]":"101401.1","Tissue RNA - lung [nTPM]":"11855.8","Tissue RNA - lymph node [nTPM]":"3820.4","Tissue RNA - medulla oblongata [nTPM]":"102081.7","Tissue RNA - midbrain [nTPM]":"90689.2","Tissue RNA - ovary [nTPM]":"8957.6","Tissue RNA - pancreas [nTPM]":"21476.2","Tissue RNA - parathyroid gland [nTPM]":"15709.9","Tissue RNA - pituitary gland [nTPM]":"12834.3","Tissue RNA - placenta [nTPM]":"7692.4","Tissue RNA - pons [nTPM]":"97098.9","Tissue RNA - prostate [nTPM]":"22214.5","Tissue RNA - rectum [nTPM]":"15007.9","Tissue RNA - retina [nTPM]":"14112.1","Tissue RNA - salivary gland [nTPM]":"17508.5","Tissue RNA - seminal vesicle [nTPM]":"11691.2","Tissue RNA - skeletal muscle [nTPM]":"61489.1","Tissue RNA - skin 1 [nTPM]":"18268.8","Tissue RNA - small intestine [nTPM]":"25046.6","Tissue RNA - smooth muscle [nTPM]":"7116.7","Tissue RNA - spinal cord [nTPM]":"75024.9","Tissue RNA - spleen [nTPM]":"12782.7","Tissue RNA - stomach 1 [nTPM]":"39594.1","Tissue RNA - testis [nTPM]":"13571.1","Tissue RNA - thalamus [nTPM]":"91494.4","Tissue RNA - thymus [nTPM]":"3233.7","Tissue RNA - thyroid gland [nTPM]":"14785.3","Tissue RNA - tongue [nTPM]":"70605.7","Tissue RNA - tonsil [nTPM]":"4913.1","Tissue RNA - urinary bladder [nTPM]":"19417.4","Tissue RNA - vagina [nTPM]":"10309.3","Tissue RNA - white matter [nTPM]":"74806.7","Cell RNA - A-431 [nTPM]":"4251.7","Cell RNA - A549 [nTPM]":"4285.9","Cell RNA - AF22 [nTPM]":"5449.6","Cell RNA - AN3-CA [nTPM]":"8075.1","Cell RNA - ASC diff [nTPM]":"12523.6","Cell RNA - ASC TERT1 [nTPM]":"3123.1","Cell RNA - BEWO [nTPM]":"3808.6","Cell RNA - BJ [nTPM]":"4184.0","Cell RNA - BJ hTERT+ [nTPM]":"1603.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"958.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1834.2","Cell RNA - CACO-2 [nTPM]":"6555.4","Cell RNA - CAPAN-2 [nTPM]":"4688.4","Cell RNA - Daudi [nTPM]":"7428.4","Cell RNA - EFO-21 [nTPM]":"3608.7","Cell RNA - fHDF\/TERT166 [nTPM]":"3590.8","Cell RNA - GAMG [nTPM]":"1396.3","Cell RNA - HaCaT [nTPM]":"7685.0","Cell RNA - HAP1 [nTPM]":"496.1","Cell RNA - HBEC3-KT [nTPM]":"6777.9","Cell RNA - HBF TERT88 [nTPM]":"1691.7","Cell RNA - HDLM-2 [nTPM]":"4330.2","Cell RNA - HEK 293 [nTPM]":"2654.6","Cell RNA - HEL [nTPM]":"4592.7","Cell RNA - HeLa [nTPM]":"41594.9","Cell RNA - Hep G2 [nTPM]":"11166.3","Cell RNA - HHSteC [nTPM]":"1884.9","Cell RNA - HL-60 [nTPM]":"4672.8","Cell RNA - HMC-1 [nTPM]":"5223.9","Cell RNA - HSkMC [nTPM]":"5330.2","Cell RNA - hTCEpi [nTPM]":"7007.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1403.3","Cell RNA - hTERT-HME1 [nTPM]":"4977.9","Cell RNA - hTERT-RPE1 [nTPM]":"8925.4","Cell RNA - HUVEC TERT2 [nTPM]":"2344.4","Cell RNA - JURKAT [nTPM]":"3683.1","Cell RNA - K-562 [nTPM]":"3908.9","Cell RNA - Karpas-707 [nTPM]":"8930.2","Cell RNA - LHCN-M2 [nTPM]":"3461.9","Cell RNA - MCF7 [nTPM]":"9508.0","Cell RNA - MOLT-4 [nTPM]":"1848.1","Cell RNA - NB-4 [nTPM]":"10481.0","Cell RNA - NTERA-2 [nTPM]":"1551.2","Cell RNA - OE19 [nTPM]":"3650.3","Cell RNA - PC-3 [nTPM]":"2876.4","Cell RNA - REH [nTPM]":"2481.0","Cell RNA - RH-30 [nTPM]":"1712.1","Cell RNA - RPMI-8226 [nTPM]":"4518.2","Cell RNA - RPTEC TERT1 [nTPM]":"6770.1","Cell RNA - RT4 [nTPM]":"8938.3","Cell RNA - SCLC-21H [nTPM]":"1999.0","Cell RNA - SH-SY5Y [nTPM]":"2694.8","Cell RNA - SiHa [nTPM]":"2434.3","Cell RNA - SK-BR-3 [nTPM]":"7967.3","Cell RNA - SK-MEL-30 [nTPM]":"4267.8","Cell RNA - SuSa [nTPM]":"9600.3","Cell RNA - T-47d [nTPM]":"5601.2","Cell RNA - THP-1 [nTPM]":"10888.7","Cell RNA - TIME [nTPM]":"6532.2","Cell RNA - U-138 MG [nTPM]":"3851.7","Cell RNA - U-2 OS [nTPM]":"3726.9","Cell RNA - U-2197 [nTPM]":"5232.7","Cell RNA - U-251 MG [nTPM]":"3330.8","Cell RNA - U-266\/70 [nTPM]":"5307.6","Cell RNA - U-266\/84 [nTPM]":"2292.6","Cell RNA - U-698 [nTPM]":"3407.7","Cell RNA - U-87 MG [nTPM]":"2514.1","Cell RNA - U-937 [nTPM]":"7881.4","Cell RNA - WM-115 [nTPM]":"2100.8","Blood RNA - basophil [nTPM]":"13456.8","Blood RNA - classical monocyte [nTPM]":"3334.1","Blood RNA - eosinophil [nTPM]":"7103.1","Blood RNA - gdT-cell [nTPM]":"1902.0","Blood RNA - intermediate monocyte [nTPM]":"2192.8","Blood RNA - MAIT T-cell [nTPM]":"2614.3","Blood RNA - memory B-cell [nTPM]":"3555.5","Blood RNA - memory CD4 T-cell [nTPM]":"2129.5","Blood RNA - memory CD8 T-cell [nTPM]":"2285.7","Blood RNA - myeloid DC [nTPM]":"1616.0","Blood RNA - naive B-cell [nTPM]":"3624.4","Blood RNA - naive CD4 T-cell [nTPM]":"2452.9","Blood RNA - naive CD8 T-cell [nTPM]":"3095.1","Blood RNA - neutrophil [nTPM]":"2513.1","Blood RNA - NK-cell [nTPM]":"2106.5","Blood RNA - non-classical monocyte [nTPM]":"2329.2","Blood RNA - plasmacytoid DC [nTPM]":"2112.6","Blood RNA - T-reg [nTPM]":"1668.2","Blood RNA - total PBMC [nTPM]":"1840.0","Brain RNA - amygdala [nTPM]":"86386.5","Brain RNA - basal ganglia [nTPM]":"83474.8","Brain RNA - cerebellum [nTPM]":"76852.9","Brain RNA - cerebral cortex [nTPM]":"119139.4","Brain RNA - hippocampal formation [nTPM]":"81116.7","Brain RNA - hypothalamus [nTPM]":"85290.4","Brain RNA - medulla oblongata [nTPM]":"102081.7","Brain RNA - midbrain [nTPM]":"90689.2","Brain RNA - pons [nTPM]":"97098.9","Brain RNA - spinal cord [nTPM]":"75024.9","Brain RNA - thalamus [nTPM]":"91494.4","Brain RNA - white matter [nTPM]":"74806.7","Single Cell Type RNA - Adipocytes [nTPM]":"3065.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1269.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1516.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6183.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4404.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9073.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7719.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2713.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6210.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6965.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"253563.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"15377.3","Single Cell Type RNA - Club cells [nTPM]":"4975.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"12806.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"4005.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"20185.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"2435.8","Single Cell Type RNA - Ductal cells [nTPM]":"2924.2","Single Cell Type RNA - Early spermatids [nTPM]":"1109.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6731.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4298.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9316.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5090.0","Single Cell Type RNA - Erythroid cells [nTPM]":"20898.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4058.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5843.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5601.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11920.4","Single Cell Type RNA - granulocytes [nTPM]":"2188.6","Single Cell Type RNA - Granulosa cells [nTPM]":"15486.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13931.3","Single Cell Type RNA - Hepatocytes [nTPM]":"35046.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14557.8","Single Cell Type RNA - Ionocytes [nTPM]":"5771.7","Single Cell Type RNA - Kupffer cells [nTPM]":"22254.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3452.7","Single Cell Type RNA - Late spermatids [nTPM]":"5132.5","Single Cell Type RNA - Leydig cells [nTPM]":"8834.9","Single Cell Type RNA - Macrophages [nTPM]":"4749.3","Single Cell Type RNA - Melanocytes [nTPM]":"3799.3","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6280.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"4212.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3710.0","Single Cell Type RNA - Paneth cells [nTPM]":"12363.2","Single Cell Type RNA - Peritubular cells [nTPM]":"5788.3","Single Cell Type RNA - Plasma cells [nTPM]":"3409.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5872.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28978.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17714.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4527.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6310.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8264.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7732.9","Single Cell Type RNA - Spermatocytes [nTPM]":"6461.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6003.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3008.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4937.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"5125.3","Single Cell Type RNA - Theca cells [nTPM]":"7671.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15595.2","Single Cell Type RNA - Urothelial cells [nTPM]":"11405.7"},{"Gene":"MT-ND4L","Gene synonym":["MTND4L","NAD4L","ND4L"],"Ensembl":"ENSG00000212907","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L","Uniprot":["P03901"],"Chromosome":"MT","Position":"10470-10766","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Leber hereditary optic neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"132930.7","heart muscle":"145078.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"30444.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"50775.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075648"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA075648":"AB_2686760"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"20104.7","Tissue RNA - adrenal gland [nTPM]":"29874.0","Tissue RNA - amygdala [nTPM]":"85794.9","Tissue RNA - appendix [nTPM]":"4122.5","Tissue RNA - basal ganglia [nTPM]":"86270.4","Tissue RNA - bone marrow [nTPM]":"3115.3","Tissue RNA - breast [nTPM]":"14930.3","Tissue RNA - cerebellum [nTPM]":"82985.5","Tissue RNA - cerebral cortex [nTPM]":"132930.7","Tissue RNA - cervix [nTPM]":"6880.0","Tissue RNA - choroid plexus [nTPM]":"93989.2","Tissue RNA - colon [nTPM]":"20616.6","Tissue RNA - duodenum [nTPM]":"9025.8","Tissue RNA - endometrium 1 [nTPM]":"7679.7","Tissue RNA - epididymis [nTPM]":"5976.7","Tissue RNA - esophagus [nTPM]":"10820.3","Tissue RNA - fallopian tube [nTPM]":"7752.4","Tissue RNA - gallbladder [nTPM]":"4365.8","Tissue RNA - heart muscle [nTPM]":"145078.7","Tissue RNA - hippocampal formation [nTPM]":"84214.9","Tissue RNA - hypothalamus [nTPM]":"90415.7","Tissue RNA - kidney [nTPM]":"46912.7","Tissue RNA - liver [nTPM]":"74928.5","Tissue RNA - lung [nTPM]":"8462.2","Tissue RNA - lymph node [nTPM]":"2787.1","Tissue RNA - medulla oblongata [nTPM]":"92948.1","Tissue RNA - midbrain [nTPM]":"87984.2","Tissue RNA - ovary [nTPM]":"6729.2","Tissue RNA - pancreas [nTPM]":"16038.2","Tissue RNA - parathyroid gland [nTPM]":"20410.6","Tissue RNA - pituitary gland [nTPM]":"9234.3","Tissue RNA - placenta [nTPM]":"5840.3","Tissue RNA - pons [nTPM]":"89012.2","Tissue RNA - prostate [nTPM]":"16438.2","Tissue RNA - rectum [nTPM]":"14044.5","Tissue RNA - retina [nTPM]":"15747.5","Tissue RNA - salivary gland [nTPM]":"12913.6","Tissue RNA - seminal vesicle [nTPM]":"12715.8","Tissue RNA - skeletal muscle [nTPM]":"58998.5","Tissue RNA - skin 1 [nTPM]":"13345.9","Tissue RNA - small intestine [nTPM]":"17015.9","Tissue RNA - smooth muscle [nTPM]":"6979.3","Tissue RNA - spinal cord [nTPM]":"79192.1","Tissue RNA - spleen [nTPM]":"7285.6","Tissue RNA - stomach 1 [nTPM]":"28192.3","Tissue RNA - testis [nTPM]":"9561.4","Tissue RNA - thalamus [nTPM]":"87700.1","Tissue RNA - thymus [nTPM]":"4435.4","Tissue RNA - thyroid gland [nTPM]":"11270.7","Tissue RNA - tongue [nTPM]":"103082.4","Tissue RNA - tonsil [nTPM]":"4852.1","Tissue RNA - urinary bladder [nTPM]":"15113.7","Tissue RNA - vagina [nTPM]":"7437.4","Tissue RNA - white matter [nTPM]":"83632.8","Cell RNA - A-431 [nTPM]":"4598.0","Cell RNA - A549 [nTPM]":"4121.5","Cell RNA - AF22 [nTPM]":"7308.1","Cell RNA - AN3-CA [nTPM]":"7468.2","Cell RNA - ASC diff [nTPM]":"25088.0","Cell RNA - ASC TERT1 [nTPM]":"5217.1","Cell RNA - BEWO [nTPM]":"3223.3","Cell RNA - BJ [nTPM]":"9523.0","Cell RNA - BJ hTERT+ [nTPM]":"2384.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1468.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2651.9","Cell RNA - CACO-2 [nTPM]":"6894.3","Cell RNA - CAPAN-2 [nTPM]":"4080.7","Cell RNA - Daudi [nTPM]":"11229.9","Cell RNA - EFO-21 [nTPM]":"3809.7","Cell RNA - fHDF\/TERT166 [nTPM]":"6497.0","Cell RNA - GAMG [nTPM]":"2387.4","Cell RNA - HaCaT [nTPM]":"8496.5","Cell RNA - HAP1 [nTPM]":"1155.8","Cell RNA - HBEC3-KT [nTPM]":"10210.3","Cell RNA - HBF TERT88 [nTPM]":"2895.1","Cell RNA - HDLM-2 [nTPM]":"4454.2","Cell RNA - HEK 293 [nTPM]":"4711.8","Cell RNA - HEL [nTPM]":"8095.9","Cell RNA - HeLa [nTPM]":"50775.4","Cell RNA - Hep G2 [nTPM]":"13024.1","Cell RNA - HHSteC [nTPM]":"3671.8","Cell RNA - HL-60 [nTPM]":"8429.4","Cell RNA - HMC-1 [nTPM]":"6965.0","Cell RNA - HSkMC [nTPM]":"9229.0","Cell RNA - hTCEpi [nTPM]":"10159.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2792.9","Cell RNA - hTERT-HME1 [nTPM]":"9675.2","Cell RNA - hTERT-RPE1 [nTPM]":"10923.1","Cell RNA - HUVEC TERT2 [nTPM]":"2983.6","Cell RNA - JURKAT [nTPM]":"5697.7","Cell RNA - K-562 [nTPM]":"4556.7","Cell RNA - Karpas-707 [nTPM]":"7771.2","Cell RNA - LHCN-M2 [nTPM]":"5412.1","Cell RNA - MCF7 [nTPM]":"8124.5","Cell RNA - MOLT-4 [nTPM]":"3199.8","Cell RNA - NB-4 [nTPM]":"10639.4","Cell RNA - NTERA-2 [nTPM]":"1846.3","Cell RNA - OE19 [nTPM]":"4811.8","Cell RNA - PC-3 [nTPM]":"4953.4","Cell RNA - REH [nTPM]":"1842.5","Cell RNA - RH-30 [nTPM]":"3155.8","Cell RNA - RPMI-8226 [nTPM]":"5025.1","Cell RNA - RPTEC TERT1 [nTPM]":"7636.0","Cell RNA - RT4 [nTPM]":"9464.9","Cell RNA - SCLC-21H [nTPM]":"2208.4","Cell RNA - SH-SY5Y [nTPM]":"2971.3","Cell RNA - SiHa [nTPM]":"4666.2","Cell RNA - SK-BR-3 [nTPM]":"7283.7","Cell RNA - SK-MEL-30 [nTPM]":"3197.8","Cell RNA - SuSa [nTPM]":"15599.0","Cell RNA - T-47d [nTPM]":"5199.9","Cell RNA - THP-1 [nTPM]":"10420.1","Cell RNA - TIME [nTPM]":"9592.2","Cell RNA - U-138 MG [nTPM]":"3792.1","Cell RNA - U-2 OS [nTPM]":"4708.5","Cell RNA - U-2197 [nTPM]":"5630.1","Cell RNA - U-251 MG [nTPM]":"3738.0","Cell RNA - U-266\/70 [nTPM]":"6985.1","Cell RNA - U-266\/84 [nTPM]":"3552.9","Cell RNA - U-698 [nTPM]":"6053.5","Cell RNA - U-87 MG [nTPM]":"2725.1","Cell RNA - U-937 [nTPM]":"11018.8","Cell RNA - WM-115 [nTPM]":"1816.1","Blood RNA - basophil [nTPM]":"16170.2","Blood RNA - classical monocyte [nTPM]":"4327.0","Blood RNA - eosinophil [nTPM]":"8286.8","Blood RNA - gdT-cell [nTPM]":"2536.0","Blood RNA - intermediate monocyte [nTPM]":"2849.6","Blood RNA - MAIT T-cell [nTPM]":"3435.6","Blood RNA - memory B-cell [nTPM]":"4233.2","Blood RNA - memory CD4 T-cell [nTPM]":"2723.9","Blood RNA - memory CD8 T-cell [nTPM]":"2939.9","Blood RNA - myeloid DC [nTPM]":"2282.7","Blood RNA - naive B-cell [nTPM]":"4618.7","Blood RNA - naive CD4 T-cell [nTPM]":"3206.8","Blood RNA - naive CD8 T-cell [nTPM]":"4006.1","Blood RNA - neutrophil [nTPM]":"2010.3","Blood RNA - NK-cell [nTPM]":"2906.4","Blood RNA - non-classical monocyte [nTPM]":"2817.9","Blood RNA - plasmacytoid DC [nTPM]":"2884.1","Blood RNA - T-reg [nTPM]":"2096.4","Blood RNA - total PBMC [nTPM]":"2551.4","Brain RNA - amygdala [nTPM]":"85794.9","Brain RNA - basal ganglia [nTPM]":"86270.4","Brain RNA - cerebellum [nTPM]":"82985.5","Brain RNA - cerebral cortex [nTPM]":"132930.7","Brain RNA - hippocampal formation [nTPM]":"84214.9","Brain RNA - hypothalamus [nTPM]":"90415.7","Brain RNA - medulla oblongata [nTPM]":"92948.1","Brain RNA - midbrain [nTPM]":"87984.2","Brain RNA - pons [nTPM]":"89012.2","Brain RNA - spinal cord [nTPM]":"79192.1","Brain RNA - thalamus [nTPM]":"87700.1","Brain RNA - white matter [nTPM]":"83632.8","Single Cell Type RNA - Adipocytes [nTPM]":"503.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"224.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"217.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2303.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"228.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"254.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"170.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5991.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"764.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"886.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30444.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1464.1","Single Cell Type RNA - Club cells [nTPM]":"438.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"323.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"449.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1428.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"90.1","Single Cell Type RNA - Ductal cells [nTPM]":"152.9","Single Cell Type RNA - Early spermatids [nTPM]":"52.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"870.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"618.8","Single Cell Type RNA - Endothelial cells [nTPM]":"942.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"256.6","Single Cell Type RNA - Erythroid cells [nTPM]":"3302.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"342.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1129.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5335.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1186.3","Single Cell Type RNA - granulocytes [nTPM]":"479.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1394.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1520.3","Single Cell Type RNA - Hepatocytes [nTPM]":"4413.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"727.8","Single Cell Type RNA - Ionocytes [nTPM]":"99.7","Single Cell Type RNA - Kupffer cells [nTPM]":"1977.9","Single Cell Type RNA - Langerhans cells [nTPM]":"193.5","Single Cell Type RNA - Late spermatids [nTPM]":"286.1","Single Cell Type RNA - Leydig cells [nTPM]":"417.2","Single Cell Type RNA - Macrophages [nTPM]":"1043.8","Single Cell Type RNA - Melanocytes [nTPM]":"256.1","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"312.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"133.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"284.5","Single Cell Type RNA - Paneth cells [nTPM]":"867.0","Single Cell Type RNA - Peritubular cells [nTPM]":"230.9","Single Cell Type RNA - Plasma cells [nTPM]":"4395.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"129.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1228.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"589.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"582.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"348.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"711.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1052.8","Single Cell Type RNA - Spermatocytes [nTPM]":"247.0","Single Cell Type RNA - Spermatogonia [nTPM]":"207.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5256.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"242.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1387.0","Single Cell Type RNA - Theca cells [nTPM]":"308.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"573.4","Single Cell Type RNA - Urothelial cells [nTPM]":"207.9"},{"Gene":"MT-ND5","Gene synonym":["MTND5","NAD5","ND5"],"Ensembl":"ENSG00000198786","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5","Uniprot":["P03915"],"Chromosome":"MT","Position":"12337-14148","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Leber hereditary optic neuropathy","Leigh syndrome","MELAS syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"25147.7","heart muscle":"26116.9","skeletal muscle":"25697.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"35040.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"10198.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"5288.6","Tissue RNA - adrenal gland [nTPM]":"4777.7","Tissue RNA - amygdala [nTPM]":"18907.8","Tissue RNA - appendix [nTPM]":"1742.2","Tissue RNA - basal ganglia [nTPM]":"18307.4","Tissue RNA - bone marrow [nTPM]":"1525.5","Tissue RNA - breast [nTPM]":"2456.7","Tissue RNA - cerebellum [nTPM]":"14400.2","Tissue RNA - cerebral cortex [nTPM]":"21432.3","Tissue RNA - cervix [nTPM]":"1614.3","Tissue RNA - choroid plexus [nTPM]":"22368.1","Tissue RNA - colon [nTPM]":"4280.6","Tissue RNA - duodenum [nTPM]":"4135.2","Tissue RNA - endometrium 1 [nTPM]":"1972.7","Tissue RNA - epididymis [nTPM]":"2508.1","Tissue RNA - esophagus [nTPM]":"2717.8","Tissue RNA - fallopian tube [nTPM]":"3030.2","Tissue RNA - gallbladder [nTPM]":"2040.5","Tissue RNA - heart muscle [nTPM]":"26116.9","Tissue RNA - hippocampal formation [nTPM]":"16370.1","Tissue RNA - hypothalamus [nTPM]":"20521.2","Tissue RNA - kidney [nTPM]":"8014.5","Tissue RNA - liver [nTPM]":"10041.3","Tissue RNA - lung [nTPM]":"2683.6","Tissue RNA - lymph node [nTPM]":"1180.6","Tissue RNA - medulla oblongata [nTPM]":"25147.7","Tissue RNA - midbrain [nTPM]":"20794.2","Tissue RNA - ovary [nTPM]":"1886.3","Tissue RNA - pancreas [nTPM]":"2631.6","Tissue RNA - parathyroid gland [nTPM]":"4813.1","Tissue RNA - pituitary gland [nTPM]":"1528.8","Tissue RNA - placenta [nTPM]":"1691.5","Tissue RNA - pons [nTPM]":"23065.0","Tissue RNA - prostate [nTPM]":"2812.7","Tissue RNA - rectum [nTPM]":"2879.0","Tissue RNA - retina [nTPM]":"3264.8","Tissue RNA - salivary gland [nTPM]":"2819.2","Tissue RNA - seminal vesicle [nTPM]":"2163.8","Tissue RNA - skeletal muscle [nTPM]":"25697.4","Tissue RNA - skin 1 [nTPM]":"6657.3","Tissue RNA - small intestine [nTPM]":"4780.7","Tissue RNA - smooth muscle [nTPM]":"2643.7","Tissue RNA - spinal cord [nTPM]":"13881.7","Tissue RNA - spleen [nTPM]":"2014.4","Tissue RNA - stomach 1 [nTPM]":"6673.9","Tissue RNA - testis [nTPM]":"1678.5","Tissue RNA - thalamus [nTPM]":"21024.6","Tissue RNA - thymus [nTPM]":"794.7","Tissue RNA - thyroid gland [nTPM]":"2059.1","Tissue RNA - tongue [nTPM]":"19444.2","Tissue RNA - tonsil [nTPM]":"1541.4","Tissue RNA - urinary bladder [nTPM]":"3557.5","Tissue RNA - vagina [nTPM]":"1537.7","Tissue RNA - white matter [nTPM]":"13870.1","Cell RNA - A-431 [nTPM]":"1615.8","Cell RNA - A549 [nTPM]":"1671.5","Cell RNA - AF22 [nTPM]":"1998.7","Cell RNA - AN3-CA [nTPM]":"1937.9","Cell RNA - ASC diff [nTPM]":"5903.9","Cell RNA - ASC TERT1 [nTPM]":"1530.3","Cell RNA - BEWO [nTPM]":"1075.8","Cell RNA - BJ [nTPM]":"3208.3","Cell RNA - BJ hTERT+ [nTPM]":"492.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"355.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"583.1","Cell RNA - CACO-2 [nTPM]":"2472.6","Cell RNA - CAPAN-2 [nTPM]":"2051.0","Cell RNA - Daudi [nTPM]":"3865.3","Cell RNA - EFO-21 [nTPM]":"1590.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1510.4","Cell RNA - GAMG [nTPM]":"397.3","Cell RNA - HaCaT [nTPM]":"3350.6","Cell RNA - HAP1 [nTPM]":"191.2","Cell RNA - HBEC3-KT [nTPM]":"1685.7","Cell RNA - HBF TERT88 [nTPM]":"583.4","Cell RNA - HDLM-2 [nTPM]":"2182.3","Cell RNA - HEK 293 [nTPM]":"1281.4","Cell RNA - HEL [nTPM]":"2840.4","Cell RNA - HeLa [nTPM]":"10198.2","Cell RNA - Hep G2 [nTPM]":"4239.2","Cell RNA - HHSteC [nTPM]":"678.8","Cell RNA - HL-60 [nTPM]":"2010.7","Cell RNA - HMC-1 [nTPM]":"2824.3","Cell RNA - HSkMC [nTPM]":"2305.4","Cell RNA - hTCEpi [nTPM]":"1315.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"401.6","Cell RNA - hTERT-HME1 [nTPM]":"951.8","Cell RNA - hTERT-RPE1 [nTPM]":"1933.5","Cell RNA - HUVEC TERT2 [nTPM]":"725.2","Cell RNA - JURKAT [nTPM]":"1233.3","Cell RNA - K-562 [nTPM]":"1056.8","Cell RNA - Karpas-707 [nTPM]":"1794.8","Cell RNA - LHCN-M2 [nTPM]":"1216.3","Cell RNA - MCF7 [nTPM]":"3046.1","Cell RNA - MOLT-4 [nTPM]":"757.3","Cell RNA - NB-4 [nTPM]":"2453.4","Cell RNA - NTERA-2 [nTPM]":"397.5","Cell RNA - OE19 [nTPM]":"910.2","Cell RNA - PC-3 [nTPM]":"903.0","Cell RNA - REH [nTPM]":"1432.9","Cell RNA - RH-30 [nTPM]":"938.2","Cell RNA - RPMI-8226 [nTPM]":"1668.7","Cell RNA - RPTEC TERT1 [nTPM]":"2083.2","Cell RNA - RT4 [nTPM]":"3132.2","Cell RNA - SCLC-21H [nTPM]":"595.0","Cell RNA - SH-SY5Y [nTPM]":"904.1","Cell RNA - SiHa [nTPM]":"1496.1","Cell RNA - SK-BR-3 [nTPM]":"2636.3","Cell RNA - SK-MEL-30 [nTPM]":"894.4","Cell RNA - SuSa [nTPM]":"3001.9","Cell RNA - T-47d [nTPM]":"1927.1","Cell RNA - THP-1 [nTPM]":"2979.2","Cell RNA - TIME [nTPM]":"5094.9","Cell RNA - U-138 MG [nTPM]":"2013.2","Cell RNA - U-2 OS [nTPM]":"1403.2","Cell RNA - U-2197 [nTPM]":"2409.7","Cell RNA - U-251 MG [nTPM]":"1271.9","Cell RNA - U-266\/70 [nTPM]":"678.8","Cell RNA - U-266\/84 [nTPM]":"1246.0","Cell RNA - U-698 [nTPM]":"1066.9","Cell RNA - U-87 MG [nTPM]":"1077.4","Cell RNA - U-937 [nTPM]":"1780.4","Cell RNA - WM-115 [nTPM]":"897.7","Blood RNA - basophil [nTPM]":"2851.8","Blood RNA - classical monocyte [nTPM]":"1521.7","Blood RNA - eosinophil [nTPM]":"874.2","Blood RNA - gdT-cell [nTPM]":"771.4","Blood RNA - intermediate monocyte [nTPM]":"980.3","Blood RNA - MAIT T-cell [nTPM]":"922.8","Blood RNA - memory B-cell [nTPM]":"979.1","Blood RNA - memory CD4 T-cell [nTPM]":"753.9","Blood RNA - memory CD8 T-cell [nTPM]":"839.2","Blood RNA - myeloid DC [nTPM]":"746.5","Blood RNA - naive B-cell [nTPM]":"1096.6","Blood RNA - naive CD4 T-cell [nTPM]":"729.2","Blood RNA - naive CD8 T-cell [nTPM]":"869.0","Blood RNA - neutrophil [nTPM]":"446.2","Blood RNA - NK-cell [nTPM]":"785.1","Blood RNA - non-classical monocyte [nTPM]":"1039.5","Blood RNA - plasmacytoid DC [nTPM]":"890.3","Blood RNA - T-reg [nTPM]":"628.6","Blood RNA - total PBMC [nTPM]":"492.0","Brain RNA - amygdala [nTPM]":"18907.8","Brain RNA - basal ganglia [nTPM]":"18307.4","Brain RNA - cerebellum [nTPM]":"14400.2","Brain RNA - cerebral cortex [nTPM]":"21432.3","Brain RNA - hippocampal formation [nTPM]":"16370.1","Brain RNA - hypothalamus [nTPM]":"20521.2","Brain RNA - medulla oblongata [nTPM]":"25147.7","Brain RNA - midbrain [nTPM]":"20794.2","Brain RNA - pons [nTPM]":"23065.0","Brain RNA - spinal cord [nTPM]":"13881.7","Brain RNA - thalamus [nTPM]":"21024.6","Brain RNA - white matter [nTPM]":"13870.1","Single Cell Type RNA - Adipocytes [nTPM]":"773.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"628.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"594.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1707.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"895.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1050.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1005.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3261.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1003.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1025.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35040.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2566.4","Single Cell Type RNA - Club cells [nTPM]":"934.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1156.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"977.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3181.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"283.7","Single Cell Type RNA - Ductal cells [nTPM]":"804.1","Single Cell Type RNA - Early spermatids [nTPM]":"109.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3130.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2025.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1614.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"782.9","Single Cell Type RNA - Erythroid cells [nTPM]":"3776.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"936.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1437.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3609.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5212.8","Single Cell Type RNA - granulocytes [nTPM]":"862.1","Single Cell Type RNA - Granulosa cells [nTPM]":"2987.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2623.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6597.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1776.8","Single Cell Type RNA - Ionocytes [nTPM]":"583.9","Single Cell Type RNA - Kupffer cells [nTPM]":"3664.2","Single Cell Type RNA - Langerhans cells [nTPM]":"661.9","Single Cell Type RNA - Late spermatids [nTPM]":"528.9","Single Cell Type RNA - Leydig cells [nTPM]":"1057.5","Single Cell Type RNA - Macrophages [nTPM]":"1364.5","Single Cell Type RNA - Melanocytes [nTPM]":"608.3","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1303.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"756.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1327.8","Single Cell Type RNA - Paneth cells [nTPM]":"2211.7","Single Cell Type RNA - Peritubular cells [nTPM]":"848.6","Single Cell Type RNA - Plasma cells [nTPM]":"2674.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"753.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4484.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2410.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1282.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"696.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1941.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1558.6","Single Cell Type RNA - Spermatocytes [nTPM]":"652.2","Single Cell Type RNA - Spermatogonia [nTPM]":"521.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3002.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"973.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1527.8","Single Cell Type RNA - Theca cells [nTPM]":"1560.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1650.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1506.6"},{"Gene":"MT-ND6","Gene synonym":["MTND6","NAD6","ND6"],"Ensembl":"ENSG00000198695","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6","Uniprot":["P03923"],"Chromosome":"MT","Position":"14149-14673","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Dystonia","Leber hereditary optic neuropathy","Leigh syndrome","MELAS syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"35802.7","skeletal muscle":"57879.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Cardiomyocytes":"15756.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"20826.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.91e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"7945.8","Tissue RNA - adrenal gland [nTPM]":"6310.2","Tissue RNA - amygdala [nTPM]":"5769.7","Tissue RNA - appendix [nTPM]":"3186.7","Tissue RNA - basal ganglia [nTPM]":"3927.7","Tissue RNA - bone marrow [nTPM]":"3253.0","Tissue RNA - breast [nTPM]":"3096.2","Tissue RNA - cerebellum [nTPM]":"2199.5","Tissue RNA - cerebral cortex [nTPM]":"5682.5","Tissue RNA - cervix [nTPM]":"2191.3","Tissue RNA - choroid plexus [nTPM]":"13970.3","Tissue RNA - colon [nTPM]":"6452.8","Tissue RNA - duodenum [nTPM]":"7840.8","Tissue RNA - endometrium 1 [nTPM]":"3145.2","Tissue RNA - epididymis [nTPM]":"54.5","Tissue RNA - esophagus [nTPM]":"5822.6","Tissue RNA - fallopian tube [nTPM]":"5447.4","Tissue RNA - gallbladder [nTPM]":"3433.9","Tissue RNA - heart muscle [nTPM]":"35802.7","Tissue RNA - hippocampal formation [nTPM]":"4361.1","Tissue RNA - hypothalamus [nTPM]":"7820.0","Tissue RNA - kidney [nTPM]":"9569.5","Tissue RNA - liver [nTPM]":"11697.0","Tissue RNA - lung [nTPM]":"4598.5","Tissue RNA - lymph node [nTPM]":"2503.1","Tissue RNA - medulla oblongata [nTPM]":"13167.2","Tissue RNA - midbrain [nTPM]":"11029.3","Tissue RNA - ovary [nTPM]":"2126.9","Tissue RNA - pancreas [nTPM]":"4152.4","Tissue RNA - parathyroid gland [nTPM]":"69.3","Tissue RNA - pituitary gland [nTPM]":"1372.8","Tissue RNA - placenta [nTPM]":"953.0","Tissue RNA - pons [nTPM]":"13713.7","Tissue RNA - prostate [nTPM]":"2509.5","Tissue RNA - rectum [nTPM]":"97.7","Tissue RNA - retina [nTPM]":"4313.6","Tissue RNA - salivary gland [nTPM]":"4084.0","Tissue RNA - seminal vesicle [nTPM]":"40.6","Tissue RNA - skeletal muscle [nTPM]":"57879.2","Tissue RNA - skin 1 [nTPM]":"15225.1","Tissue RNA - small intestine [nTPM]":"8006.6","Tissue RNA - smooth muscle [nTPM]":"51.8","Tissue RNA - spinal cord [nTPM]":"1229.7","Tissue RNA - spleen [nTPM]":"4205.8","Tissue RNA - stomach 1 [nTPM]":"10030.4","Tissue RNA - testis [nTPM]":"1993.1","Tissue RNA - thalamus [nTPM]":"8318.4","Tissue RNA - thymus [nTPM]":"40.9","Tissue RNA - thyroid gland [nTPM]":"2562.5","Tissue RNA - tongue [nTPM]":"243.6","Tissue RNA - tonsil [nTPM]":"43.1","Tissue RNA - urinary bladder [nTPM]":"5236.3","Tissue RNA - vagina [nTPM]":"1897.2","Tissue RNA - white matter [nTPM]":"1060.7","Cell RNA - A-431 [nTPM]":"3305.7","Cell RNA - A549 [nTPM]":"2595.3","Cell RNA - AF22 [nTPM]":"2255.7","Cell RNA - AN3-CA [nTPM]":"2869.4","Cell RNA - ASC diff [nTPM]":"371.0","Cell RNA - ASC TERT1 [nTPM]":"34.6","Cell RNA - BEWO [nTPM]":"1614.6","Cell RNA - BJ [nTPM]":"4329.1","Cell RNA - BJ hTERT+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.2","Cell RNA - CACO-2 [nTPM]":"3553.8","Cell RNA - CAPAN-2 [nTPM]":"3233.4","Cell RNA - Daudi [nTPM]":"6999.5","Cell RNA - EFO-21 [nTPM]":"2873.3","Cell RNA - fHDF\/TERT166 [nTPM]":"117.5","Cell RNA - GAMG [nTPM]":"423.7","Cell RNA - HaCaT [nTPM]":"4781.1","Cell RNA - HAP1 [nTPM]":"25.1","Cell RNA - HBEC3-KT [nTPM]":"79.1","Cell RNA - HBF TERT88 [nTPM]":"23.3","Cell RNA - HDLM-2 [nTPM]":"4178.5","Cell RNA - HEK 293 [nTPM]":"1966.3","Cell RNA - HEL [nTPM]":"4217.6","Cell RNA - HeLa [nTPM]":"20826.9","Cell RNA - Hep G2 [nTPM]":"10361.0","Cell RNA - HHSteC [nTPM]":"29.7","Cell RNA - HL-60 [nTPM]":"2704.1","Cell RNA - HMC-1 [nTPM]":"3805.1","Cell RNA - HSkMC [nTPM]":"64.4","Cell RNA - hTCEpi [nTPM]":"103.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"103.9","Cell RNA - hTERT-HME1 [nTPM]":"86.4","Cell RNA - hTERT-RPE1 [nTPM]":"2123.1","Cell RNA - HUVEC TERT2 [nTPM]":"23.2","Cell RNA - JURKAT [nTPM]":"1445.3","Cell RNA - K-562 [nTPM]":"1855.2","Cell RNA - Karpas-707 [nTPM]":"2671.0","Cell RNA - LHCN-M2 [nTPM]":"94.5","Cell RNA - MCF7 [nTPM]":"6976.5","Cell RNA - MOLT-4 [nTPM]":"836.0","Cell RNA - NB-4 [nTPM]":"3680.9","Cell RNA - NTERA-2 [nTPM]":"492.5","Cell RNA - OE19 [nTPM]":"1868.7","Cell RNA - PC-3 [nTPM]":"1267.3","Cell RNA - REH [nTPM]":"2002.7","Cell RNA - RH-30 [nTPM]":"1440.3","Cell RNA - RPMI-8226 [nTPM]":"3034.3","Cell RNA - RPTEC TERT1 [nTPM]":"60.9","Cell RNA - RT4 [nTPM]":"9493.6","Cell RNA - SCLC-21H [nTPM]":"926.2","Cell RNA - SH-SY5Y [nTPM]":"1476.3","Cell RNA - SiHa [nTPM]":"2250.2","Cell RNA - SK-BR-3 [nTPM]":"3898.6","Cell RNA - SK-MEL-30 [nTPM]":"1876.3","Cell RNA - SuSa [nTPM]":"3559.0","Cell RNA - T-47d [nTPM]":"3037.2","Cell RNA - THP-1 [nTPM]":"5182.3","Cell RNA - TIME [nTPM]":"8822.6","Cell RNA - U-138 MG [nTPM]":"2473.6","Cell RNA - U-2 OS [nTPM]":"2088.6","Cell RNA - U-2197 [nTPM]":"3550.5","Cell RNA - U-251 MG [nTPM]":"1766.8","Cell RNA - U-266\/70 [nTPM]":"906.6","Cell RNA - U-266\/84 [nTPM]":"2600.9","Cell RNA - U-698 [nTPM]":"1705.0","Cell RNA - U-87 MG [nTPM]":"1682.9","Cell RNA - U-937 [nTPM]":"2680.8","Cell RNA - WM-115 [nTPM]":"1473.8","Blood RNA - basophil [nTPM]":"2089.0","Blood RNA - classical monocyte [nTPM]":"1092.3","Blood RNA - eosinophil [nTPM]":"645.1","Blood RNA - gdT-cell [nTPM]":"733.4","Blood RNA - intermediate monocyte [nTPM]":"881.5","Blood RNA - MAIT T-cell [nTPM]":"840.2","Blood RNA - memory B-cell [nTPM]":"1047.3","Blood RNA - memory CD4 T-cell [nTPM]":"776.1","Blood RNA - memory CD8 T-cell [nTPM]":"800.0","Blood RNA - myeloid DC [nTPM]":"582.8","Blood RNA - naive B-cell [nTPM]":"1016.1","Blood RNA - naive CD4 T-cell [nTPM]":"760.2","Blood RNA - naive CD8 T-cell [nTPM]":"870.6","Blood RNA - neutrophil [nTPM]":"453.3","Blood RNA - NK-cell [nTPM]":"752.2","Blood RNA - non-classical monocyte [nTPM]":"963.0","Blood RNA - plasmacytoid DC [nTPM]":"790.6","Blood RNA - T-reg [nTPM]":"635.2","Blood RNA - total PBMC [nTPM]":"365.4","Brain RNA - amygdala [nTPM]":"5769.7","Brain RNA - basal ganglia [nTPM]":"3927.7","Brain RNA - cerebellum [nTPM]":"2199.5","Brain RNA - cerebral cortex [nTPM]":"5682.5","Brain RNA - hippocampal formation [nTPM]":"4361.1","Brain RNA - hypothalamus [nTPM]":"7820.0","Brain RNA - medulla oblongata [nTPM]":"13167.2","Brain RNA - midbrain [nTPM]":"11029.3","Brain RNA - pons [nTPM]":"13713.7","Brain RNA - spinal cord [nTPM]":"1229.7","Brain RNA - thalamus [nTPM]":"8318.4","Brain RNA - white matter [nTPM]":"1060.7","Single Cell Type RNA - Adipocytes [nTPM]":"31.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"328.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"55.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1210.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"52.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15756.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"273.1","Single Cell Type RNA - Club cells [nTPM]":"107.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"128.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"78.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"125.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"32.6","Single Cell Type RNA - Early spermatids [nTPM]":"8.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"154.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"132.5","Single Cell Type RNA - Endothelial cells [nTPM]":"478.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.1","Single Cell Type RNA - Erythroid cells [nTPM]":"797.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"396.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"886.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"247.7","Single Cell Type RNA - granulocytes [nTPM]":"98.0","Single Cell Type RNA - Granulosa cells [nTPM]":"130.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"385.8","Single Cell Type RNA - Hepatocytes [nTPM]":"699.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"59.8","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"518.3","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"33.4","Single Cell Type RNA - Leydig cells [nTPM]":"62.4","Single Cell Type RNA - Macrophages [nTPM]":"214.3","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"66.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.6","Single Cell Type RNA - Paneth cells [nTPM]":"69.9","Single Cell Type RNA - Peritubular cells [nTPM]":"45.1","Single Cell Type RNA - Plasma cells [nTPM]":"1055.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"152.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"76.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"175.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"111.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"121.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"423.9","Single Cell Type RNA - Spermatocytes [nTPM]":"31.7","Single Cell Type RNA - Spermatogonia [nTPM]":"60.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1160.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"266.3","Single Cell Type RNA - Theca cells [nTPM]":"58.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"78.4","Single Cell Type RNA - Urothelial cells [nTPM]":"117.0"},{"Gene":"MTMR2","Gene synonym":["CMT4B","KIAA1073"],"Ensembl":"ENSG00000087053","Gene description":"Myotubularin related protein 2","Uniprot":["Q13614"],"Chromosome":"11","Position":"95821766-95925315","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"120.1","Oligodendrocytes":"226.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049831"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049831":"AB_2680904"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.7","Tissue RNA - adrenal gland [nTPM]":"9.3","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"16.8","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"16.3","Tissue RNA - cerebral cortex [nTPM]":"18.3","Tissue RNA - cervix [nTPM]":"12.2","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"12.9","Tissue RNA - duodenum [nTPM]":"7.1","Tissue RNA - endometrium 1 [nTPM]":"12.3","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"14.7","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"14.3","Tissue RNA - heart muscle [nTPM]":"13.5","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"14.3","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"4.3","Tissue RNA - lung [nTPM]":"12.3","Tissue RNA - lymph node [nTPM]":"9.5","Tissue RNA - medulla oblongata [nTPM]":"15.1","Tissue RNA - midbrain [nTPM]":"14.4","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"12.7","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"24.5","Tissue RNA - pons [nTPM]":"15.8","Tissue RNA - prostate [nTPM]":"16.1","Tissue RNA - rectum [nTPM]":"13.9","Tissue RNA - retina [nTPM]":"18.6","Tissue RNA - salivary gland [nTPM]":"20.5","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"6.2","Tissue RNA - skin 1 [nTPM]":"8.2","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"18.0","Tissue RNA - spinal cord [nTPM]":"13.5","Tissue RNA - spleen [nTPM]":"8.6","Tissue RNA - stomach 1 [nTPM]":"13.0","Tissue RNA - testis [nTPM]":"31.0","Tissue RNA - thalamus [nTPM]":"14.1","Tissue RNA - thymus [nTPM]":"15.1","Tissue RNA - thyroid gland [nTPM]":"9.9","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"12.1","Tissue RNA - urinary bladder [nTPM]":"15.2","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"22.4","Cell RNA - A-431 [nTPM]":"24.1","Cell RNA - A549 [nTPM]":"25.3","Cell RNA - AF22 [nTPM]":"54.1","Cell RNA - AN3-CA [nTPM]":"39.2","Cell RNA - ASC diff [nTPM]":"19.2","Cell RNA - ASC TERT1 [nTPM]":"29.0","Cell RNA - BEWO [nTPM]":"47.5","Cell RNA - BJ [nTPM]":"43.3","Cell RNA - BJ hTERT+ [nTPM]":"37.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.8","Cell RNA - CACO-2 [nTPM]":"57.3","Cell RNA - CAPAN-2 [nTPM]":"47.1","Cell RNA - Daudi [nTPM]":"16.2","Cell RNA - EFO-21 [nTPM]":"50.3","Cell RNA - fHDF\/TERT166 [nTPM]":"45.5","Cell RNA - GAMG [nTPM]":"35.9","Cell RNA - HaCaT [nTPM]":"30.9","Cell RNA - HAP1 [nTPM]":"47.7","Cell RNA - HBEC3-KT [nTPM]":"48.2","Cell RNA - HBF TERT88 [nTPM]":"38.9","Cell RNA - HDLM-2 [nTPM]":"30.8","Cell RNA - HEK 293 [nTPM]":"21.3","Cell RNA - HEL [nTPM]":"31.5","Cell RNA - HeLa [nTPM]":"55.0","Cell RNA - Hep G2 [nTPM]":"33.0","Cell RNA - HHSteC [nTPM]":"42.8","Cell RNA - HL-60 [nTPM]":"59.3","Cell RNA - HMC-1 [nTPM]":"26.7","Cell RNA - HSkMC [nTPM]":"24.0","Cell RNA - hTCEpi [nTPM]":"31.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.6","Cell RNA - hTERT-HME1 [nTPM]":"54.5","Cell RNA - hTERT-RPE1 [nTPM]":"41.8","Cell RNA - HUVEC TERT2 [nTPM]":"64.4","Cell RNA - JURKAT [nTPM]":"35.4","Cell RNA - K-562 [nTPM]":"44.7","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"39.6","Cell RNA - MCF7 [nTPM]":"17.9","Cell RNA - MOLT-4 [nTPM]":"29.0","Cell RNA - NB-4 [nTPM]":"27.2","Cell RNA - NTERA-2 [nTPM]":"46.6","Cell RNA - OE19 [nTPM]":"59.0","Cell RNA - PC-3 [nTPM]":"34.9","Cell RNA - REH [nTPM]":"23.2","Cell RNA - RH-30 [nTPM]":"32.2","Cell RNA - RPMI-8226 [nTPM]":"16.8","Cell RNA - RPTEC TERT1 [nTPM]":"43.9","Cell RNA - RT4 [nTPM]":"125.0","Cell RNA - SCLC-21H [nTPM]":"35.6","Cell RNA - SH-SY5Y [nTPM]":"40.6","Cell RNA - SiHa [nTPM]":"43.6","Cell RNA - SK-BR-3 [nTPM]":"36.4","Cell RNA - SK-MEL-30 [nTPM]":"19.2","Cell RNA - SuSa [nTPM]":"35.1","Cell RNA - T-47d [nTPM]":"27.6","Cell RNA - THP-1 [nTPM]":"26.5","Cell RNA - TIME [nTPM]":"64.4","Cell RNA - U-138 MG [nTPM]":"47.7","Cell RNA - U-2 OS [nTPM]":"45.1","Cell RNA - U-2197 [nTPM]":"34.4","Cell RNA - U-251 MG [nTPM]":"41.1","Cell RNA - U-266\/70 [nTPM]":"13.1","Cell RNA - U-266\/84 [nTPM]":"42.4","Cell RNA - U-698 [nTPM]":"14.3","Cell RNA - U-87 MG [nTPM]":"20.4","Cell RNA - U-937 [nTPM]":"15.6","Cell RNA - WM-115 [nTPM]":"50.6","Blood RNA - basophil [nTPM]":"9.8","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"12.4","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"13.4","Blood RNA - memory B-cell [nTPM]":"5.8","Blood RNA - memory CD4 T-cell [nTPM]":"7.9","Blood RNA - memory CD8 T-cell [nTPM]":"15.7","Blood RNA - myeloid DC [nTPM]":"7.6","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"11.3","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"14.1","Blood RNA - non-classical monocyte [nTPM]":"7.2","Blood RNA - plasmacytoid DC [nTPM]":"3.7","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"7.8","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"16.8","Brain RNA - cerebellum [nTPM]":"16.3","Brain RNA - cerebral cortex [nTPM]":"18.3","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"14.3","Brain RNA - medulla oblongata [nTPM]":"15.1","Brain RNA - midbrain [nTPM]":"14.4","Brain RNA - pons [nTPM]":"15.8","Brain RNA - spinal cord [nTPM]":"13.5","Brain RNA - thalamus [nTPM]":"14.1","Brain RNA - white matter [nTPM]":"22.4","Single Cell Type RNA - Adipocytes [nTPM]":"19.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"9.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"11.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - dendritic cells [nTPM]":"8.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"17.8","Single Cell Type RNA - Early spermatids [nTPM]":"74.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.1","Single Cell Type RNA - Endothelial cells [nTPM]":"20.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"69.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.3","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"49.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.8","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"10.3","Single Cell Type RNA - Langerhans cells [nTPM]":"8.2","Single Cell Type RNA - Late spermatids [nTPM]":"120.1","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"8.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"6.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"63.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"226.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.0","Single Cell Type RNA - Spermatocytes [nTPM]":"46.8","Single Cell Type RNA - Spermatogonia [nTPM]":"19.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"8.8","Single Cell Type RNA - Theca cells [nTPM]":"12.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.6","Single Cell Type RNA - Urothelial cells [nTPM]":"15.6"},{"Gene":"MUSK","Gene synonym":[],"Ensembl":"ENSG00000030304","Gene description":"Muscle associated receptor tyrosine kinase","Uniprot":["O15146"],"Chromosome":"9","Position":"110668779-110806558","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein","Kinase","Muscle protein","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.2","skeletal muscle":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"4.8","Leydig cells":"5.3","Oligodendrocytes":"17.0","Peritubular cells":"19.5","Skeletal myocytes":"23.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"LHCN-M2":"24.7","RH-30":"23.7"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"5.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"4.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"24.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"23.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MYH14","Gene synonym":["DFNA4","FLJ13881","KIAA2034","MHC16","MYH17"],"Ensembl":"ENSG00000105357","Gene description":"Myosin heavy chain 14","Uniprot":["Q7Z406"],"Chromosome":"19","Position":"50188186-50310542","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell shape"],"Molecular function":["Actin-binding","Calmodulin-binding","Motor protein","Myosin"],"Disease involvement":["Deafness","Disease variant","Neuropathy","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"191.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"487.2","Paneth cells":"306.4","Proximal enterocytes":"376.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"48.6","CAPAN-2":"59.4","HaCaT":"119.0","MCF7":"59.0","OE19":"61.7","RT4":"147.8","SK-BR-3":"51.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062391","HPA067889","HPA070260"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9600000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA062391":"AB_2684748","HPA067889":"AB_2685917","HPA070260":"AB_2686243"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.97e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.83e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Tissue RNA - adipose tissue [nTPM]":"12.6","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"24.1","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"35.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"8.8","Tissue RNA - cerebellum [nTPM]":"38.2","Tissue RNA - cerebral cortex [nTPM]":"23.3","Tissue RNA - cervix [nTPM]":"13.3","Tissue RNA - choroid plexus [nTPM]":"22.0","Tissue RNA - colon [nTPM]":"64.5","Tissue RNA - duodenum [nTPM]":"83.8","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"63.7","Tissue RNA - fallopian tube [nTPM]":"15.4","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"41.3","Tissue RNA - hippocampal formation [nTPM]":"20.0","Tissue RNA - hypothalamus [nTPM]":"30.9","Tissue RNA - kidney [nTPM]":"10.2","Tissue RNA - liver [nTPM]":"25.4","Tissue RNA - lung [nTPM]":"24.4","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"38.7","Tissue RNA - midbrain [nTPM]":"35.6","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"17.3","Tissue RNA - parathyroid gland [nTPM]":"16.7","Tissue RNA - pituitary gland [nTPM]":"18.5","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"35.7","Tissue RNA - prostate [nTPM]":"8.8","Tissue RNA - rectum [nTPM]":"19.5","Tissue RNA - retina [nTPM]":"5.1","Tissue RNA - salivary gland [nTPM]":"44.0","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"191.3","Tissue RNA - skin 1 [nTPM]":"87.7","Tissue RNA - small intestine [nTPM]":"76.7","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"29.5","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"45.5","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"34.4","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"33.2","Tissue RNA - tongue [nTPM]":"35.1","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"11.0","Tissue RNA - vagina [nTPM]":"31.8","Tissue RNA - white matter [nTPM]":"37.4","Cell RNA - A-431 [nTPM]":"48.6","Cell RNA - A549 [nTPM]":"5.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"25.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"7.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"33.1","Cell RNA - CAPAN-2 [nTPM]":"59.4","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"30.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.7","Cell RNA - HaCaT [nTPM]":"119.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"25.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"3.4","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"59.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"61.7","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"29.4","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"147.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"2.9","Cell RNA - SK-BR-3 [nTPM]":"51.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"9.7","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"11.7","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"11.2","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"24.1","Brain RNA - basal ganglia [nTPM]":"35.0","Brain RNA - cerebellum [nTPM]":"38.2","Brain RNA - cerebral cortex [nTPM]":"23.3","Brain RNA - hippocampal formation [nTPM]":"20.0","Brain RNA - hypothalamus [nTPM]":"30.9","Brain RNA - medulla oblongata [nTPM]":"38.7","Brain RNA - midbrain [nTPM]":"35.6","Brain RNA - pons [nTPM]":"35.7","Brain RNA - spinal cord [nTPM]":"29.5","Brain RNA - thalamus [nTPM]":"34.4","Brain RNA - white matter [nTPM]":"37.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.5","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"50.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"57.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"487.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"53.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"58.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"51.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"85.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"70.7","Single Cell Type RNA - granulocytes [nTPM]":"14.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"45.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"109.4","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"19.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"67.5","Single Cell Type RNA - Paneth cells [nTPM]":"306.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"376.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"80.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"122.8","Single Cell Type RNA - Urothelial cells [nTPM]":"86.2"},{"Gene":"MYH9","Gene synonym":["DFNA17","EPSTS","FTNS","MHA","NMHC-II-A","NMMHCA"],"Ensembl":"ENSG00000100345","Gene description":"Myosin heavy chain 9","Uniprot":["P35579"],"Chromosome":"22","Position":"36281280-36387967","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion","Cell shape"],"Molecular function":["Actin-binding","Calmodulin-binding","Motor protein","Myosin"],"Disease involvement":["Alport syndrome","Cancer-related genes","Cataract","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"TIME":"1343.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001644","CAB015386","HPA064783"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"410000000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Plasma membrane","Actin filaments"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"CAB015386":"AB_784698","HPA001644":"AB_1079439","HPA064783":"AB_2732721"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"295.9","Tissue RNA - adrenal gland [nTPM]":"95.5","Tissue RNA - amygdala [nTPM]":"42.3","Tissue RNA - appendix [nTPM]":"181.1","Tissue RNA - basal ganglia [nTPM]":"42.1","Tissue RNA - bone marrow [nTPM]":"245.9","Tissue RNA - breast [nTPM]":"231.5","Tissue RNA - cerebellum [nTPM]":"40.6","Tissue RNA - cerebral cortex [nTPM]":"54.7","Tissue RNA - cervix [nTPM]":"181.2","Tissue RNA - choroid plexus [nTPM]":"65.5","Tissue RNA - colon [nTPM]":"192.6","Tissue RNA - duodenum [nTPM]":"107.0","Tissue RNA - endometrium 1 [nTPM]":"356.4","Tissue RNA - epididymis [nTPM]":"39.3","Tissue RNA - esophagus [nTPM]":"153.8","Tissue RNA - fallopian tube [nTPM]":"182.2","Tissue RNA - gallbladder [nTPM]":"134.5","Tissue RNA - heart muscle [nTPM]":"161.1","Tissue RNA - hippocampal formation [nTPM]":"50.8","Tissue RNA - hypothalamus [nTPM]":"39.4","Tissue RNA - kidney [nTPM]":"140.7","Tissue RNA - liver [nTPM]":"101.6","Tissue RNA - lung [nTPM]":"286.2","Tissue RNA - lymph node [nTPM]":"161.7","Tissue RNA - medulla oblongata [nTPM]":"52.7","Tissue RNA - midbrain [nTPM]":"51.7","Tissue RNA - ovary [nTPM]":"121.1","Tissue RNA - pancreas [nTPM]":"160.3","Tissue RNA - parathyroid gland [nTPM]":"55.0","Tissue RNA - pituitary gland [nTPM]":"52.6","Tissue RNA - placenta [nTPM]":"166.5","Tissue RNA - pons [nTPM]":"48.1","Tissue RNA - prostate [nTPM]":"131.8","Tissue RNA - rectum [nTPM]":"89.8","Tissue RNA - retina [nTPM]":"9.7","Tissue RNA - salivary gland [nTPM]":"177.2","Tissue RNA - seminal vesicle [nTPM]":"98.4","Tissue RNA - skeletal muscle [nTPM]":"84.0","Tissue RNA - skin 1 [nTPM]":"160.6","Tissue RNA - small intestine [nTPM]":"163.5","Tissue RNA - smooth muscle [nTPM]":"174.1","Tissue RNA - spinal cord [nTPM]":"48.8","Tissue RNA - spleen [nTPM]":"232.5","Tissue RNA - stomach 1 [nTPM]":"135.8","Tissue RNA - testis [nTPM]":"38.2","Tissue RNA - thalamus [nTPM]":"52.1","Tissue RNA - thymus [nTPM]":"125.1","Tissue RNA - thyroid gland [nTPM]":"141.2","Tissue RNA - tongue [nTPM]":"46.3","Tissue RNA - tonsil [nTPM]":"104.1","Tissue RNA - urinary bladder [nTPM]":"168.8","Tissue RNA - vagina [nTPM]":"166.8","Tissue RNA - white matter [nTPM]":"48.2","Cell RNA - A-431 [nTPM]":"612.2","Cell RNA - A549 [nTPM]":"277.0","Cell RNA - AF22 [nTPM]":"86.2","Cell RNA - AN3-CA [nTPM]":"74.2","Cell RNA - ASC diff [nTPM]":"156.8","Cell RNA - ASC TERT1 [nTPM]":"195.1","Cell RNA - BEWO [nTPM]":"437.3","Cell RNA - BJ [nTPM]":"398.4","Cell RNA - BJ hTERT+ [nTPM]":"507.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"554.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"413.2","Cell RNA - CACO-2 [nTPM]":"302.1","Cell RNA - CAPAN-2 [nTPM]":"170.3","Cell RNA - Daudi [nTPM]":"156.9","Cell RNA - EFO-21 [nTPM]":"230.1","Cell RNA - fHDF\/TERT166 [nTPM]":"666.1","Cell RNA - GAMG [nTPM]":"265.0","Cell RNA - HaCaT [nTPM]":"412.7","Cell RNA - HAP1 [nTPM]":"125.2","Cell RNA - HBEC3-KT [nTPM]":"779.4","Cell RNA - HBF TERT88 [nTPM]":"559.6","Cell RNA - HDLM-2 [nTPM]":"356.1","Cell RNA - HEK 293 [nTPM]":"120.9","Cell RNA - HEL [nTPM]":"302.6","Cell RNA - HeLa [nTPM]":"294.3","Cell RNA - Hep G2 [nTPM]":"259.9","Cell RNA - HHSteC [nTPM]":"481.1","Cell RNA - HL-60 [nTPM]":"346.9","Cell RNA - HMC-1 [nTPM]":"463.8","Cell RNA - HSkMC [nTPM]":"233.0","Cell RNA - hTCEpi [nTPM]":"234.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"751.9","Cell RNA - hTERT-HME1 [nTPM]":"626.4","Cell RNA - hTERT-RPE1 [nTPM]":"540.3","Cell RNA - HUVEC TERT2 [nTPM]":"461.8","Cell RNA - JURKAT [nTPM]":"113.2","Cell RNA - K-562 [nTPM]":"67.3","Cell RNA - Karpas-707 [nTPM]":"205.8","Cell RNA - LHCN-M2 [nTPM]":"448.9","Cell RNA - MCF7 [nTPM]":"161.9","Cell RNA - MOLT-4 [nTPM]":"124.4","Cell RNA - NB-4 [nTPM]":"204.0","Cell RNA - NTERA-2 [nTPM]":"51.7","Cell RNA - OE19 [nTPM]":"171.1","Cell RNA - PC-3 [nTPM]":"169.2","Cell RNA - REH [nTPM]":"233.3","Cell RNA - RH-30 [nTPM]":"267.3","Cell RNA - RPMI-8226 [nTPM]":"146.7","Cell RNA - RPTEC TERT1 [nTPM]":"314.5","Cell RNA - RT4 [nTPM]":"581.5","Cell RNA - SCLC-21H [nTPM]":"129.6","Cell RNA - SH-SY5Y [nTPM]":"53.0","Cell RNA - SiHa [nTPM]":"559.7","Cell RNA - SK-BR-3 [nTPM]":"217.0","Cell RNA - SK-MEL-30 [nTPM]":"251.6","Cell RNA - SuSa [nTPM]":"218.5","Cell RNA - T-47d [nTPM]":"162.4","Cell RNA - THP-1 [nTPM]":"177.1","Cell RNA - TIME [nTPM]":"1343.7","Cell RNA - U-138 MG [nTPM]":"1222.6","Cell RNA - U-2 OS [nTPM]":"370.3","Cell RNA - U-2197 [nTPM]":"237.5","Cell RNA - U-251 MG [nTPM]":"731.5","Cell RNA - U-266\/70 [nTPM]":"135.2","Cell RNA - U-266\/84 [nTPM]":"114.7","Cell RNA - U-698 [nTPM]":"129.0","Cell RNA - U-87 MG [nTPM]":"463.2","Cell RNA - U-937 [nTPM]":"172.3","Cell RNA - WM-115 [nTPM]":"363.1","Blood RNA - basophil [nTPM]":"72.6","Blood RNA - classical monocyte [nTPM]":"25.2","Blood RNA - eosinophil [nTPM]":"64.7","Blood RNA - gdT-cell [nTPM]":"32.4","Blood RNA - intermediate monocyte [nTPM]":"19.8","Blood RNA - MAIT T-cell [nTPM]":"28.4","Blood RNA - memory B-cell [nTPM]":"13.4","Blood RNA - memory CD4 T-cell [nTPM]":"23.5","Blood RNA - memory CD8 T-cell [nTPM]":"26.4","Blood RNA - myeloid DC [nTPM]":"17.2","Blood RNA - naive B-cell [nTPM]":"11.9","Blood RNA - naive CD4 T-cell [nTPM]":"18.3","Blood RNA - naive CD8 T-cell [nTPM]":"20.4","Blood RNA - neutrophil [nTPM]":"41.2","Blood RNA - NK-cell [nTPM]":"9.0","Blood RNA - non-classical monocyte [nTPM]":"26.5","Blood RNA - plasmacytoid DC [nTPM]":"8.0","Blood RNA - T-reg [nTPM]":"26.3","Blood RNA - total PBMC [nTPM]":"54.5","Brain RNA - amygdala [nTPM]":"42.3","Brain RNA - basal ganglia [nTPM]":"42.1","Brain RNA - cerebellum [nTPM]":"40.6","Brain RNA - cerebral cortex [nTPM]":"54.7","Brain RNA - hippocampal formation [nTPM]":"50.8","Brain RNA - hypothalamus [nTPM]":"39.4","Brain RNA - medulla oblongata [nTPM]":"52.7","Brain RNA - midbrain [nTPM]":"51.7","Brain RNA - pons [nTPM]":"48.1","Brain RNA - spinal cord [nTPM]":"48.8","Brain RNA - thalamus [nTPM]":"52.1","Brain RNA - white matter [nTPM]":"48.2","Single Cell Type RNA - Adipocytes [nTPM]":"303.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"118.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"87.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"108.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"144.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"182.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"123.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"72.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"90.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"89.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"62.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"80.1","Single Cell Type RNA - Club cells [nTPM]":"89.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"92.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"87.0","Single Cell Type RNA - dendritic cells [nTPM]":"151.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"359.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"309.4","Single Cell Type RNA - Early spermatids [nTPM]":"35.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"89.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"121.6","Single Cell Type RNA - Endothelial cells [nTPM]":"258.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"73.8","Single Cell Type RNA - Erythroid cells [nTPM]":"51.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"245.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"193.1","Single Cell Type RNA - Fibroblasts [nTPM]":"82.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"123.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"194.7","Single Cell Type RNA - granulocytes [nTPM]":"93.1","Single Cell Type RNA - Granulosa cells [nTPM]":"117.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"132.8","Single Cell Type RNA - Hepatocytes [nTPM]":"102.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"100.4","Single Cell Type RNA - Horizontal cells [nTPM]":"82.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"131.0","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"119.6","Single Cell Type RNA - Langerhans cells [nTPM]":"124.2","Single Cell Type RNA - Late spermatids [nTPM]":"37.4","Single Cell Type RNA - Leydig cells [nTPM]":"68.0","Single Cell Type RNA - Macrophages [nTPM]":"168.8","Single Cell Type RNA - Melanocytes [nTPM]":"85.4","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"196.6","Single Cell Type RNA - Muller glia cells [nTPM]":"11.9","Single Cell Type RNA - NK-cells [nTPM]":"137.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"344.6","Single Cell Type RNA - Paneth cells [nTPM]":"186.8","Single Cell Type RNA - Peritubular cells [nTPM]":"211.4","Single Cell Type RNA - Plasma cells [nTPM]":"125.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"184.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"159.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"51.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.3","Single Cell Type RNA - Sertoli cells [nTPM]":"203.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"275.2","Single Cell Type RNA - Spermatocytes [nTPM]":"6.9","Single Cell Type RNA - Spermatogonia [nTPM]":"10.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"133.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"135.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.4","Single Cell Type RNA - T-cells [nTPM]":"213.2","Single Cell Type RNA - Theca cells [nTPM]":"141.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"139.5","Single Cell Type RNA - Urothelial cells [nTPM]":"134.3"},{"Gene":"MYO15A","Gene synonym":["DFNB3","MYO15"],"Ensembl":"ENSG00000091536","Gene description":"Myosin XVA","Uniprot":["Q9UKN7"],"Chromosome":"17","Position":"18108706-18179802","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":["Actin-binding","Calmodulin-binding","Motor protein","Myosin"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"pituitary gland":"62.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"69.9","Late spermatids":"53.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.4"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078501"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078501":"AB_2732383"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"62.9","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"2.1","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"7.2","Tissue RNA - thalamus [nTPM]":"1.4","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"2.1","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"1.4","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"69.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"53.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"9.2","Single Cell Type RNA - Spermatogonia [nTPM]":"13.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"MYO3A","Gene synonym":["DFNB30"],"Ensembl":"ENSG00000095777","Gene description":"Myosin IIIA","Uniprot":["Q8NEV4"],"Chromosome":"10","Position":"25934229-26212532","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Hearing","Sensory transduction","Vision"],"Molecular function":["Actin-binding","Kinase","Motor protein","Myosin","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"15.5","testis":"5.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"156.6","Late spermatids":"58.2","Muller glia cells":"74.8","Spermatocytes":"31.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"1.3","CAPAN-2":"1.2","HEK 293":"1.5","SCLC-21H":"1.4","U-2 OS":"2.4","U-698":"6.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051893","HPA075413"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Actin filaments","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Actin filaments","Cytoplasmic bodies"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA051893":null,"HPA075413":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"15.5","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"6.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"156.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"58.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"74.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"31.7","Single Cell Type RNA - Spermatogonia [nTPM]":"14.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"MYO6","Gene synonym":["DFNA22","DFNB37","KIAA0389"],"Ensembl":"ENSG00000196586","Gene description":"Myosin VI","Uniprot":["Q9UM54"],"Chromosome":"6","Position":"75749192-75919537","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Endocytosis","Hearing","Protein transport","Transport"],"Molecular function":["Actin-binding","Calmodulin-binding","Motor protein","Myosin"],"Disease involvement":["Cardiomyopathy","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"409.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"5.5","MAIT T-cell":"3.0","memory CD4 T-cell":"1.8","memory CD8 T-cell":"3.1","naive CD8 T-cell":"3.0","NK-cell":"2.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"2.9","T-cells":"5.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RT4":"103.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010762","HPA035482","HPA035483"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB010762":"AB_477166","HPA035482":null,"HPA035483":"AB_2674647"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.27e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"18.6","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"29.3","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"28.3","Tissue RNA - cerebellum [nTPM]":"22.6","Tissue RNA - cerebral cortex [nTPM]":"32.0","Tissue RNA - cervix [nTPM]":"18.5","Tissue RNA - choroid plexus [nTPM]":"32.6","Tissue RNA - colon [nTPM]":"22.1","Tissue RNA - duodenum [nTPM]":"33.0","Tissue RNA - endometrium 1 [nTPM]":"7.6","Tissue RNA - epididymis [nTPM]":"22.9","Tissue RNA - esophagus [nTPM]":"32.0","Tissue RNA - fallopian tube [nTPM]":"11.5","Tissue RNA - gallbladder [nTPM]":"27.0","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"19.6","Tissue RNA - hypothalamus [nTPM]":"19.5","Tissue RNA - kidney [nTPM]":"51.4","Tissue RNA - liver [nTPM]":"15.2","Tissue RNA - lung [nTPM]":"23.2","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"23.7","Tissue RNA - midbrain [nTPM]":"24.4","Tissue RNA - ovary [nTPM]":"4.7","Tissue RNA - pancreas [nTPM]":"21.6","Tissue RNA - parathyroid gland [nTPM]":"40.4","Tissue RNA - pituitary gland [nTPM]":"14.5","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"24.3","Tissue RNA - prostate [nTPM]":"17.2","Tissue RNA - rectum [nTPM]":"19.2","Tissue RNA - retina [nTPM]":"49.0","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"19.9","Tissue RNA - skeletal muscle [nTPM]":"3.4","Tissue RNA - skin 1 [nTPM]":"16.8","Tissue RNA - small intestine [nTPM]":"33.9","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"16.0","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"27.6","Tissue RNA - testis [nTPM]":"14.6","Tissue RNA - thalamus [nTPM]":"23.9","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"15.9","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"12.8","Tissue RNA - urinary bladder [nTPM]":"24.0","Tissue RNA - vagina [nTPM]":"15.8","Tissue RNA - white matter [nTPM]":"34.6","Cell RNA - A-431 [nTPM]":"52.2","Cell RNA - A549 [nTPM]":"13.0","Cell RNA - AF22 [nTPM]":"12.3","Cell RNA - AN3-CA [nTPM]":"8.9","Cell RNA - ASC diff [nTPM]":"29.7","Cell RNA - ASC TERT1 [nTPM]":"23.7","Cell RNA - BEWO [nTPM]":"42.6","Cell RNA - BJ [nTPM]":"20.7","Cell RNA - BJ hTERT+ [nTPM]":"23.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.3","Cell RNA - CACO-2 [nTPM]":"22.2","Cell RNA - CAPAN-2 [nTPM]":"44.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"16.1","Cell RNA - fHDF\/TERT166 [nTPM]":"25.7","Cell RNA - GAMG [nTPM]":"14.0","Cell RNA - HaCaT [nTPM]":"40.0","Cell RNA - HAP1 [nTPM]":"15.3","Cell RNA - HBEC3-KT [nTPM]":"29.2","Cell RNA - HBF TERT88 [nTPM]":"18.6","Cell RNA - HDLM-2 [nTPM]":"17.0","Cell RNA - HEK 293 [nTPM]":"30.3","Cell RNA - HEL [nTPM]":"17.4","Cell RNA - HeLa [nTPM]":"5.6","Cell RNA - Hep G2 [nTPM]":"14.1","Cell RNA - HHSteC [nTPM]":"25.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"22.2","Cell RNA - HSkMC [nTPM]":"17.5","Cell RNA - hTCEpi [nTPM]":"21.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.3","Cell RNA - hTERT-HME1 [nTPM]":"14.5","Cell RNA - hTERT-RPE1 [nTPM]":"24.0","Cell RNA - HUVEC TERT2 [nTPM]":"43.3","Cell RNA - JURKAT [nTPM]":"7.9","Cell RNA - K-562 [nTPM]":"22.4","Cell RNA - Karpas-707 [nTPM]":"7.2","Cell RNA - LHCN-M2 [nTPM]":"15.4","Cell RNA - MCF7 [nTPM]":"48.3","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"7.7","Cell RNA - OE19 [nTPM]":"44.1","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"29.1","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"51.1","Cell RNA - RT4 [nTPM]":"103.6","Cell RNA - SCLC-21H [nTPM]":"26.8","Cell RNA - SH-SY5Y [nTPM]":"14.8","Cell RNA - SiHa [nTPM]":"5.6","Cell RNA - SK-BR-3 [nTPM]":"46.6","Cell RNA - SK-MEL-30 [nTPM]":"6.8","Cell RNA - SuSa [nTPM]":"28.3","Cell RNA - T-47d [nTPM]":"16.5","Cell RNA - THP-1 [nTPM]":"35.8","Cell RNA - TIME [nTPM]":"59.4","Cell RNA - U-138 MG [nTPM]":"13.7","Cell RNA - U-2 OS [nTPM]":"9.3","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"20.0","Cell RNA - U-266\/70 [nTPM]":"13.2","Cell RNA - U-266\/84 [nTPM]":"16.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"10.9","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"5.3","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"5.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"18.6","Brain RNA - basal ganglia [nTPM]":"29.3","Brain RNA - cerebellum [nTPM]":"22.6","Brain RNA - cerebral cortex [nTPM]":"32.0","Brain RNA - hippocampal formation [nTPM]":"19.6","Brain RNA - hypothalamus [nTPM]":"19.5","Brain RNA - medulla oblongata [nTPM]":"23.7","Brain RNA - midbrain [nTPM]":"24.4","Brain RNA - pons [nTPM]":"24.3","Brain RNA - spinal cord [nTPM]":"16.0","Brain RNA - thalamus [nTPM]":"23.9","Brain RNA - white matter [nTPM]":"34.6","Single Cell Type RNA - Adipocytes [nTPM]":"74.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"141.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"207.0","Single Cell Type RNA - Astrocytes [nTPM]":"286.3","Single Cell Type RNA - B-cells [nTPM]":"4.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"87.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"49.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"83.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"99.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"35.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"91.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"150.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"120.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.0","Single Cell Type RNA - dendritic cells [nTPM]":"14.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"112.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"54.8","Single Cell Type RNA - Ductal cells [nTPM]":"128.9","Single Cell Type RNA - Early spermatids [nTPM]":"7.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"86.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.9","Single Cell Type RNA - Endothelial cells [nTPM]":"57.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"85.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"147.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"120.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.8","Single Cell Type RNA - Fibroblasts [nTPM]":"30.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"91.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"169.2","Single Cell Type RNA - granulocytes [nTPM]":"26.0","Single Cell Type RNA - Granulosa cells [nTPM]":"81.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.9","Single Cell Type RNA - Hepatocytes [nTPM]":"33.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.3","Single Cell Type RNA - Horizontal cells [nTPM]":"95.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"167.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"76.4","Single Cell Type RNA - Ionocytes [nTPM]":"116.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"6.1","Single Cell Type RNA - Late spermatids [nTPM]":"9.6","Single Cell Type RNA - Leydig cells [nTPM]":"30.1","Single Cell Type RNA - Macrophages [nTPM]":"6.7","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"105.9","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"307.3","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"179.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"409.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"197.0","Single Cell Type RNA - Paneth cells [nTPM]":"99.7","Single Cell Type RNA - Peritubular cells [nTPM]":"43.2","Single Cell Type RNA - Plasma cells [nTPM]":"11.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"165.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"105.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"97.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"109.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"188.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.7","Single Cell Type RNA - Spermatocytes [nTPM]":"14.4","Single Cell Type RNA - Spermatogonia [nTPM]":"32.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"78.4","Single Cell Type RNA - T-cells [nTPM]":"13.4","Single Cell Type RNA - Theca cells [nTPM]":"191.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"77.5","Single Cell Type RNA - Urothelial cells [nTPM]":"199.7"},{"Gene":"MYO7A","Gene synonym":["DFNA11","DFNB2","NSRD2","USH1B"],"Ensembl":"ENSG00000137474","Gene description":"Myosin VIIA","Uniprot":["Q13402"],"Chromosome":"11","Position":"77128246-77215241","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":["Actin-binding","Calmodulin-binding","Motor protein","Myosin"],"Disease involvement":["Deafness","Disease variant","Leber congenital amaurosis","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"41.9","choroid plexus":"53.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"47.9","Cytotrophoblasts":"42.3","Hofbauer cells":"30.1","Kupffer cells":"17.8","Rod photoreceptor cells":"31.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"2.6","intermediate monocyte":"1.7"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"monocytes":"2.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"11.8","CACO-2":"9.0","RH-30":"19.5","RPMI-8226":"13.8","SK-BR-3":"10.5","U-937":"18.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034059"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034059":"AB_2148626"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"41.9","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"53.2","Tissue RNA - colon [nTPM]":"2.8","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"2.7","Tissue RNA - gallbladder [nTPM]":"2.8","Tissue RNA - heart muscle [nTPM]":"2.5","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"8.6","Tissue RNA - kidney [nTPM]":"4.3","Tissue RNA - liver [nTPM]":"23.3","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"5.2","Tissue RNA - pancreas [nTPM]":"5.4","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"19.1","Tissue RNA - placenta [nTPM]":"16.0","Tissue RNA - pons [nTPM]":"8.4","Tissue RNA - prostate [nTPM]":"2.4","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"27.4","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"2.8","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"15.8","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"24.5","Tissue RNA - thalamus [nTPM]":"5.1","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"11.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"9.0","Cell RNA - CAPAN-2 [nTPM]":"2.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"5.7","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"3.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"19.5","Cell RNA - RPMI-8226 [nTPM]":"13.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"2.9","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"10.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"2.2","Cell RNA - T-47d [nTPM]":"1.3","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"18.9","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"8.6","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"8.4","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"5.1","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"14.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"16.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"17.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.4","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"7.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"17.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.1","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"3.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"MYO9A","Gene synonym":["FLJ11061","FLJ13244","MGC71859"],"Ensembl":"ENSG00000066933","Gene description":"Myosin IXA","Uniprot":["B2RTY4"],"Chromosome":"15","Position":"71822291-72118577","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding","GTPase activation","Motor protein","Myosin"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"61.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"225.5","Inhibitory neurons":"192.9","Rod photoreceptor cells":"462.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"43.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039812","HPA040071"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA039812":"AB_10961421","HPA040071":"AB_10961117"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.5","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"11.3","Tissue RNA - appendix [nTPM]":"4.8","Tissue RNA - basal ganglia [nTPM]":"14.9","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"10.7","Tissue RNA - cerebellum [nTPM]":"14.3","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"7.1","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"9.9","Tissue RNA - epididymis [nTPM]":"7.4","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"12.8","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"13.7","Tissue RNA - liver [nTPM]":"3.7","Tissue RNA - lung [nTPM]":"8.8","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"8.7","Tissue RNA - midbrain [nTPM]":"8.0","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"9.2","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"6.3","Tissue RNA - retina [nTPM]":"61.7","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"8.1","Tissue RNA - skin 1 [nTPM]":"8.7","Tissue RNA - small intestine [nTPM]":"4.6","Tissue RNA - smooth muscle [nTPM]":"10.2","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"7.3","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"28.7","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"6.7","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"14.9","Tissue RNA - tonsil [nTPM]":"6.4","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"13.5","Cell RNA - A-431 [nTPM]":"9.7","Cell RNA - A549 [nTPM]":"14.6","Cell RNA - AF22 [nTPM]":"9.6","Cell RNA - AN3-CA [nTPM]":"6.8","Cell RNA - ASC diff [nTPM]":"14.2","Cell RNA - ASC TERT1 [nTPM]":"16.5","Cell RNA - BEWO [nTPM]":"5.7","Cell RNA - BJ [nTPM]":"9.1","Cell RNA - BJ hTERT+ [nTPM]":"9.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"6.6","Cell RNA - Daudi [nTPM]":"43.3","Cell RNA - EFO-21 [nTPM]":"5.4","Cell RNA - fHDF\/TERT166 [nTPM]":"17.9","Cell RNA - GAMG [nTPM]":"11.8","Cell RNA - HaCaT [nTPM]":"9.0","Cell RNA - HAP1 [nTPM]":"19.2","Cell RNA - HBEC3-KT [nTPM]":"10.3","Cell RNA - HBF TERT88 [nTPM]":"11.9","Cell RNA - HDLM-2 [nTPM]":"9.5","Cell RNA - HEK 293 [nTPM]":"11.1","Cell RNA - HEL [nTPM]":"11.1","Cell RNA - HeLa [nTPM]":"8.9","Cell RNA - Hep G2 [nTPM]":"3.2","Cell RNA - HHSteC [nTPM]":"9.0","Cell RNA - HL-60 [nTPM]":"11.2","Cell RNA - HMC-1 [nTPM]":"8.5","Cell RNA - HSkMC [nTPM]":"9.5","Cell RNA - hTCEpi [nTPM]":"10.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.6","Cell RNA - hTERT-HME1 [nTPM]":"15.2","Cell RNA - hTERT-RPE1 [nTPM]":"7.6","Cell RNA - HUVEC TERT2 [nTPM]":"11.5","Cell RNA - JURKAT [nTPM]":"7.7","Cell RNA - K-562 [nTPM]":"7.2","Cell RNA - Karpas-707 [nTPM]":"10.3","Cell RNA - LHCN-M2 [nTPM]":"12.2","Cell RNA - MCF7 [nTPM]":"6.0","Cell RNA - MOLT-4 [nTPM]":"6.4","Cell RNA - NB-4 [nTPM]":"4.5","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"3.5","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"18.2","Cell RNA - RPMI-8226 [nTPM]":"4.3","Cell RNA - RPTEC TERT1 [nTPM]":"10.9","Cell RNA - RT4 [nTPM]":"14.3","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"5.9","Cell RNA - SiHa [nTPM]":"12.0","Cell RNA - SK-BR-3 [nTPM]":"10.0","Cell RNA - SK-MEL-30 [nTPM]":"9.5","Cell RNA - SuSa [nTPM]":"11.6","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"5.3","Cell RNA - TIME [nTPM]":"15.5","Cell RNA - U-138 MG [nTPM]":"18.0","Cell RNA - U-2 OS [nTPM]":"8.7","Cell RNA - U-2197 [nTPM]":"29.7","Cell RNA - U-251 MG [nTPM]":"10.4","Cell RNA - U-266\/70 [nTPM]":"6.5","Cell RNA - U-266\/84 [nTPM]":"17.3","Cell RNA - U-698 [nTPM]":"11.3","Cell RNA - U-87 MG [nTPM]":"10.8","Cell RNA - U-937 [nTPM]":"9.2","Cell RNA - WM-115 [nTPM]":"8.1","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"3.7","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"4.9","Blood RNA - memory B-cell [nTPM]":"3.1","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"6.3","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"11.3","Brain RNA - basal ganglia [nTPM]":"14.9","Brain RNA - cerebellum [nTPM]":"14.3","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"12.8","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"8.7","Brain RNA - midbrain [nTPM]":"8.0","Brain RNA - pons [nTPM]":"9.2","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"13.5","Single Cell Type RNA - Adipocytes [nTPM]":"37.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"115.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"77.4","Single Cell Type RNA - Astrocytes [nTPM]":"145.6","Single Cell Type RNA - B-cells [nTPM]":"18.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"56.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"24.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - dendritic cells [nTPM]":"30.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"131.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"47.3","Single Cell Type RNA - Endothelial cells [nTPM]":"29.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.6","Single Cell Type RNA - Erythroid cells [nTPM]":"19.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"225.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.3","Single Cell Type RNA - Fibroblasts [nTPM]":"35.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.2","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"53.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"5.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.0","Single Cell Type RNA - Horizontal cells [nTPM]":"53.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"192.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"54.8","Single Cell Type RNA - Langerhans cells [nTPM]":"10.0","Single Cell Type RNA - Late spermatids [nTPM]":"161.9","Single Cell Type RNA - Leydig cells [nTPM]":"38.8","Single Cell Type RNA - Macrophages [nTPM]":"17.7","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"113.4","Single Cell Type RNA - monocytes [nTPM]":"13.0","Single Cell Type RNA - Muller glia cells [nTPM]":"24.0","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"177.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"180.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.9","Single Cell Type RNA - Paneth cells [nTPM]":"15.5","Single Cell Type RNA - Peritubular cells [nTPM]":"42.9","Single Cell Type RNA - Plasma cells [nTPM]":"12.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"462.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.6","Single Cell Type RNA - Spermatocytes [nTPM]":"115.2","Single Cell Type RNA - Spermatogonia [nTPM]":"41.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - T-cells [nTPM]":"18.5","Single Cell Type RNA - Theca cells [nTPM]":"17.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.8","Single Cell Type RNA - Urothelial cells [nTPM]":"15.7"},{"Gene":"MYOC","Gene synonym":["GLC1A","JOAG1","TIGR"],"Ensembl":"ENSG00000034971","Gene description":"Myocilin","Uniprot":["Q99972"],"Chromosome":"1","Position":"171635417-171652688","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Glaucoma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"110.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Fibroblasts":"244.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"melanoma":"13.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027364"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027364":"AB_10602036"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"47.1","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"19.2","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"3.5","Tissue RNA - endometrium 1 [nTPM]":"16.5","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"19.6","Tissue RNA - fallopian tube [nTPM]":"15.3","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"18.3","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"7.4","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"3.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"14.0","Tissue RNA - seminal vesicle [nTPM]":"6.4","Tissue RNA - skeletal muscle [nTPM]":"33.8","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"50.2","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"14.1","Tissue RNA - thyroid gland [nTPM]":"28.7","Tissue RNA - tongue [nTPM]":"110.8","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"22.6","Tissue RNA - vagina [nTPM]":"9.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"12.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"244.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"2.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MYORG","Gene synonym":["KIAA1161","NET37"],"Ensembl":"ENSG00000164976","Gene description":"Myogenesis regulating glycosidase (putative)","Uniprot":["Q6NSJ0"],"Chromosome":"9","Position":"34366666-34376898","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"84.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"9.6","Cytotrophoblasts":"55.5","Exocrine glandular cells":"11.8","Pancreatic endocrine cells":"10.3","Proximal tubular cells":"9.2","Syncytiotrophoblasts":"17.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"35.4","SK-BR-3":"56.8","T-47d":"52.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060533","HPA067487"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA060533":"AB_2684311","HPA067487":"AB_2685848"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.96e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.20e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.1","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"30.6","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"30.3","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"27.1","Tissue RNA - cerebral cortex [nTPM]":"31.5","Tissue RNA - cervix [nTPM]":"1.7","Tissue RNA - choroid plexus [nTPM]":"16.8","Tissue RNA - colon [nTPM]":"19.0","Tissue RNA - duodenum [nTPM]":"27.3","Tissue RNA - endometrium 1 [nTPM]":"2.7","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"6.1","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"28.4","Tissue RNA - hypothalamus [nTPM]":"28.2","Tissue RNA - kidney [nTPM]":"14.5","Tissue RNA - liver [nTPM]":"41.5","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"34.0","Tissue RNA - midbrain [nTPM]":"33.5","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"11.1","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"19.8","Tissue RNA - pons [nTPM]":"28.7","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"16.2","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"5.6","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"84.2","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"25.8","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"24.5","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"15.0","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"31.8","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"39.2","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"3.1","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"24.2","Cell RNA - A-431 [nTPM]":"8.1","Cell RNA - A549 [nTPM]":"5.5","Cell RNA - AF22 [nTPM]":"9.2","Cell RNA - AN3-CA [nTPM]":"5.6","Cell RNA - ASC diff [nTPM]":"3.8","Cell RNA - ASC TERT1 [nTPM]":"1.2","Cell RNA - BEWO [nTPM]":"19.7","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"13.9","Cell RNA - CAPAN-2 [nTPM]":"8.3","Cell RNA - Daudi [nTPM]":"4.4","Cell RNA - EFO-21 [nTPM]":"15.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1.4","Cell RNA - GAMG [nTPM]":"4.0","Cell RNA - HaCaT [nTPM]":"16.4","Cell RNA - HAP1 [nTPM]":"6.7","Cell RNA - HBEC3-KT [nTPM]":"15.5","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"3.6","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"24.6","Cell RNA - Hep G2 [nTPM]":"35.4","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"2.7","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"7.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.6","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"3.3","Cell RNA - K-562 [nTPM]":"1.1","Cell RNA - Karpas-707 [nTPM]":"4.2","Cell RNA - LHCN-M2 [nTPM]":"2.0","Cell RNA - MCF7 [nTPM]":"13.4","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"5.5","Cell RNA - OE19 [nTPM]":"27.4","Cell RNA - PC-3 [nTPM]":"4.4","Cell RNA - REH [nTPM]":"4.0","Cell RNA - RH-30 [nTPM]":"4.6","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"4.9","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"13.0","Cell RNA - SiHa [nTPM]":"10.8","Cell RNA - SK-BR-3 [nTPM]":"56.8","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"7.8","Cell RNA - T-47d [nTPM]":"52.8","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"3.2","Cell RNA - U-138 MG [nTPM]":"1.8","Cell RNA - U-2 OS [nTPM]":"11.0","Cell RNA - U-2197 [nTPM]":"1.6","Cell RNA - U-251 MG [nTPM]":"3.5","Cell RNA - U-266\/70 [nTPM]":"2.8","Cell RNA - U-266\/84 [nTPM]":"6.5","Cell RNA - U-698 [nTPM]":"1.6","Cell RNA - U-87 MG [nTPM]":"1.6","Cell RNA - U-937 [nTPM]":"3.1","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"30.6","Brain RNA - basal ganglia [nTPM]":"30.3","Brain RNA - cerebellum [nTPM]":"27.1","Brain RNA - cerebral cortex [nTPM]":"31.5","Brain RNA - hippocampal formation [nTPM]":"28.4","Brain RNA - hypothalamus [nTPM]":"28.2","Brain RNA - medulla oblongata [nTPM]":"34.0","Brain RNA - midbrain [nTPM]":"33.5","Brain RNA - pons [nTPM]":"28.7","Brain RNA - spinal cord [nTPM]":"24.5","Brain RNA - thalamus [nTPM]":"31.8","Brain RNA - white matter [nTPM]":"24.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MYRF","Gene synonym":["C11orf9","MRF","Ndt80","pqn-47"],"Ensembl":"ENSG00000124920","Gene description":"Myelin regulatory factor","Uniprot":["Q9Y2G1"],"Chromosome":"11","Position":"61752636-61788518","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Hydrolase","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"168.0","stomach 1":"88.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"48.1","Cholangiocytes":"60.1","Gastric mucus-secreting cells":"130.0","Oligodendrocytes":"255.8","Pancreatic endocrine cells":"70.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"38.8","CACO-2":"63.6","CAPAN-2":"34.0","EFO-21":"48.6","Hep G2":"21.8","OE19":"37.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018310"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA018310":"AB_1845534"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.4","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"31.3","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"99.0","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"67.9","Tissue RNA - cerebral cortex [nTPM]":"67.5","Tissue RNA - cervix [nTPM]":"2.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.8","Tissue RNA - duodenum [nTPM]":"11.4","Tissue RNA - endometrium 1 [nTPM]":"13.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"15.4","Tissue RNA - gallbladder [nTPM]":"17.3","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"36.9","Tissue RNA - hypothalamus [nTPM]":"48.8","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"16.9","Tissue RNA - lung [nTPM]":"22.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"101.7","Tissue RNA - midbrain [nTPM]":"89.4","Tissue RNA - ovary [nTPM]":"17.6","Tissue RNA - pancreas [nTPM]":"31.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"84.9","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"43.5","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"88.3","Tissue RNA - testis [nTPM]":"3.1","Tissue RNA - thalamus [nTPM]":"85.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"168.0","Cell RNA - A-431 [nTPM]":"3.1","Cell RNA - A549 [nTPM]":"38.8","Cell RNA - AF22 [nTPM]":"4.7","Cell RNA - AN3-CA [nTPM]":"1.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"63.6","Cell RNA - CAPAN-2 [nTPM]":"34.0","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"48.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.2","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"21.8","Cell RNA - HHSteC [nTPM]":"18.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"11.7","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"37.2","Cell RNA - PC-3 [nTPM]":"4.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"6.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"10.6","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"1.4","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"19.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"31.3","Brain RNA - basal ganglia [nTPM]":"99.0","Brain RNA - cerebellum [nTPM]":"67.9","Brain RNA - cerebral cortex [nTPM]":"67.5","Brain RNA - hippocampal formation [nTPM]":"36.9","Brain RNA - hypothalamus [nTPM]":"48.8","Brain RNA - medulla oblongata [nTPM]":"101.7","Brain RNA - midbrain [nTPM]":"89.4","Brain RNA - pons [nTPM]":"84.9","Brain RNA - spinal cord [nTPM]":"43.5","Brain RNA - thalamus [nTPM]":"85.7","Brain RNA - white matter [nTPM]":"168.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"60.1","Single Cell Type RNA - Club cells [nTPM]":"3.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"31.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"130.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"6.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"255.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"70.5","Single Cell Type RNA - Paneth cells [nTPM]":"13.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"NARS2","Gene synonym":["DFNB94","FLJ23441","SLM5"],"Ensembl":"ENSG00000137513","Gene description":"Asparaginyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q96I59"],"Chromosome":"11","Position":"78435968-78574874","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Deafness","Disease variant","Leigh syndrome","Non-syndromic deafness","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026793"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA026793":"AB_1848833"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.39e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.22e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"11.9","Tissue RNA - amygdala [nTPM]":"10.7","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"12.3","Tissue RNA - bone marrow [nTPM]":"6.2","Tissue RNA - breast [nTPM]":"11.1","Tissue RNA - cerebellum [nTPM]":"12.4","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"19.8","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"9.1","Tissue RNA - epididymis [nTPM]":"11.2","Tissue RNA - esophagus [nTPM]":"8.1","Tissue RNA - fallopian tube [nTPM]":"9.9","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"19.0","Tissue RNA - liver [nTPM]":"23.5","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"9.6","Tissue RNA - medulla oblongata [nTPM]":"11.7","Tissue RNA - midbrain [nTPM]":"13.9","Tissue RNA - ovary [nTPM]":"11.4","Tissue RNA - pancreas [nTPM]":"10.6","Tissue RNA - parathyroid gland [nTPM]":"11.4","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"10.8","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"13.4","Tissue RNA - salivary gland [nTPM]":"10.7","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"23.5","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"9.7","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"11.3","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"9.9","Tissue RNA - testis [nTPM]":"7.5","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"11.5","Tissue RNA - tongue [nTPM]":"19.6","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"8.1","Tissue RNA - white matter [nTPM]":"12.3","Cell RNA - A-431 [nTPM]":"16.7","Cell RNA - A549 [nTPM]":"22.8","Cell RNA - AF22 [nTPM]":"23.5","Cell RNA - AN3-CA [nTPM]":"15.4","Cell RNA - ASC diff [nTPM]":"16.1","Cell RNA - ASC TERT1 [nTPM]":"13.5","Cell RNA - BEWO [nTPM]":"19.5","Cell RNA - BJ [nTPM]":"13.5","Cell RNA - BJ hTERT+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.9","Cell RNA - CACO-2 [nTPM]":"39.4","Cell RNA - CAPAN-2 [nTPM]":"17.4","Cell RNA - Daudi [nTPM]":"40.9","Cell RNA - EFO-21 [nTPM]":"34.1","Cell RNA - fHDF\/TERT166 [nTPM]":"8.7","Cell RNA - GAMG [nTPM]":"19.8","Cell RNA - HaCaT [nTPM]":"21.5","Cell RNA - HAP1 [nTPM]":"39.9","Cell RNA - HBEC3-KT [nTPM]":"26.3","Cell RNA - HBF TERT88 [nTPM]":"28.3","Cell RNA - HDLM-2 [nTPM]":"27.0","Cell RNA - HEK 293 [nTPM]":"21.3","Cell RNA - HEL [nTPM]":"28.9","Cell RNA - HeLa [nTPM]":"17.3","Cell RNA - Hep G2 [nTPM]":"33.7","Cell RNA - HHSteC [nTPM]":"13.3","Cell RNA - HL-60 [nTPM]":"31.3","Cell RNA - HMC-1 [nTPM]":"10.1","Cell RNA - HSkMC [nTPM]":"9.4","Cell RNA - hTCEpi [nTPM]":"16.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.1","Cell RNA - hTERT-HME1 [nTPM]":"32.0","Cell RNA - hTERT-RPE1 [nTPM]":"18.3","Cell RNA - HUVEC TERT2 [nTPM]":"17.9","Cell RNA - JURKAT [nTPM]":"33.7","Cell RNA - K-562 [nTPM]":"44.5","Cell RNA - Karpas-707 [nTPM]":"11.0","Cell RNA - LHCN-M2 [nTPM]":"23.1","Cell RNA - MCF7 [nTPM]":"19.4","Cell RNA - MOLT-4 [nTPM]":"32.7","Cell RNA - NB-4 [nTPM]":"50.3","Cell RNA - NTERA-2 [nTPM]":"25.6","Cell RNA - OE19 [nTPM]":"67.3","Cell RNA - PC-3 [nTPM]":"27.3","Cell RNA - REH [nTPM]":"33.6","Cell RNA - RH-30 [nTPM]":"38.2","Cell RNA - RPMI-8226 [nTPM]":"55.5","Cell RNA - RPTEC TERT1 [nTPM]":"27.2","Cell RNA - RT4 [nTPM]":"23.0","Cell RNA - SCLC-21H [nTPM]":"27.8","Cell RNA - SH-SY5Y [nTPM]":"17.5","Cell RNA - SiHa [nTPM]":"20.1","Cell RNA - SK-BR-3 [nTPM]":"25.4","Cell RNA - SK-MEL-30 [nTPM]":"35.5","Cell RNA - SuSa [nTPM]":"25.1","Cell RNA - T-47d [nTPM]":"24.1","Cell RNA - THP-1 [nTPM]":"12.3","Cell RNA - TIME [nTPM]":"10.9","Cell RNA - U-138 MG [nTPM]":"27.7","Cell RNA - U-2 OS [nTPM]":"32.8","Cell RNA - U-2197 [nTPM]":"32.0","Cell RNA - U-251 MG [nTPM]":"23.1","Cell RNA - U-266\/70 [nTPM]":"18.1","Cell RNA - U-266\/84 [nTPM]":"33.1","Cell RNA - U-698 [nTPM]":"91.1","Cell RNA - U-87 MG [nTPM]":"5.4","Cell RNA - U-937 [nTPM]":"27.7","Cell RNA - WM-115 [nTPM]":"19.2","Blood RNA - basophil [nTPM]":"9.5","Blood RNA - classical monocyte [nTPM]":"9.3","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"11.1","Blood RNA - intermediate monocyte [nTPM]":"10.4","Blood RNA - MAIT T-cell [nTPM]":"13.8","Blood RNA - memory B-cell [nTPM]":"17.6","Blood RNA - memory CD4 T-cell [nTPM]":"12.8","Blood RNA - memory CD8 T-cell [nTPM]":"12.5","Blood RNA - myeloid DC [nTPM]":"16.6","Blood RNA - naive B-cell [nTPM]":"15.0","Blood RNA - naive CD4 T-cell [nTPM]":"18.5","Blood RNA - naive CD8 T-cell [nTPM]":"16.7","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"20.3","Blood RNA - non-classical monocyte [nTPM]":"12.8","Blood RNA - plasmacytoid DC [nTPM]":"12.7","Blood RNA - T-reg [nTPM]":"10.5","Blood RNA - total PBMC [nTPM]":"10.3","Brain RNA - amygdala [nTPM]":"10.7","Brain RNA - basal ganglia [nTPM]":"12.3","Brain RNA - cerebellum [nTPM]":"12.4","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"11.7","Brain RNA - midbrain [nTPM]":"13.9","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"11.3","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"12.3","Single Cell Type RNA - Adipocytes [nTPM]":"5.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.4","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"14.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"9.5","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.6","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.0","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"14.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"19.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.3","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"11.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"2.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.3","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"42.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.5","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.8","Single Cell Type RNA - Spermatocytes [nTPM]":"8.6","Single Cell Type RNA - Spermatogonia [nTPM]":"19.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.3","Single Cell Type RNA - T-cells [nTPM]":"7.8","Single Cell Type RNA - Theca cells [nTPM]":"9.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.6","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"NAXD","Gene synonym":["CARKD","FLJ10769","LP3298"],"Ensembl":"ENSG00000213995","Gene description":"NAD(P)HX dehydratase","Uniprot":["Q8IW45"],"Chromosome":"13","Position":"110615545-110639996","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"34.8","Distal tubular cells":"39.2","Extravillous trophoblasts":"26.7","Granulosa cells":"27.6","Syncytiotrophoblasts":"30.9","Theca cells":"24.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010551"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"390000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010551":"AB_1848669"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.15e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.63e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.3","Tissue RNA - adrenal gland [nTPM]":"37.1","Tissue RNA - amygdala [nTPM]":"44.0","Tissue RNA - appendix [nTPM]":"16.0","Tissue RNA - basal ganglia [nTPM]":"43.7","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"19.4","Tissue RNA - cerebellum [nTPM]":"43.6","Tissue RNA - cerebral cortex [nTPM]":"46.3","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"40.8","Tissue RNA - colon [nTPM]":"23.1","Tissue RNA - duodenum [nTPM]":"22.9","Tissue RNA - endometrium 1 [nTPM]":"18.7","Tissue RNA - epididymis [nTPM]":"26.6","Tissue RNA - esophagus [nTPM]":"23.4","Tissue RNA - fallopian tube [nTPM]":"22.6","Tissue RNA - gallbladder [nTPM]":"21.3","Tissue RNA - heart muscle [nTPM]":"26.4","Tissue RNA - hippocampal formation [nTPM]":"45.7","Tissue RNA - hypothalamus [nTPM]":"42.8","Tissue RNA - kidney [nTPM]":"24.9","Tissue RNA - liver [nTPM]":"65.4","Tissue RNA - lung [nTPM]":"18.8","Tissue RNA - lymph node [nTPM]":"20.8","Tissue RNA - medulla oblongata [nTPM]":"45.9","Tissue RNA - midbrain [nTPM]":"45.0","Tissue RNA - ovary [nTPM]":"39.0","Tissue RNA - pancreas [nTPM]":"36.2","Tissue RNA - parathyroid gland [nTPM]":"28.4","Tissue RNA - pituitary gland [nTPM]":"22.4","Tissue RNA - placenta [nTPM]":"23.3","Tissue RNA - pons [nTPM]":"44.5","Tissue RNA - prostate [nTPM]":"25.8","Tissue RNA - rectum [nTPM]":"19.7","Tissue RNA - retina [nTPM]":"14.3","Tissue RNA - salivary gland [nTPM]":"22.8","Tissue RNA - seminal vesicle [nTPM]":"28.9","Tissue RNA - skeletal muscle [nTPM]":"31.9","Tissue RNA - skin 1 [nTPM]":"30.5","Tissue RNA - small intestine [nTPM]":"23.0","Tissue RNA - smooth muscle [nTPM]":"21.7","Tissue RNA - spinal cord [nTPM]":"43.9","Tissue RNA - spleen [nTPM]":"21.8","Tissue RNA - stomach 1 [nTPM]":"30.3","Tissue RNA - testis [nTPM]":"24.2","Tissue RNA - thalamus [nTPM]":"46.2","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"25.4","Tissue RNA - tongue [nTPM]":"33.6","Tissue RNA - tonsil [nTPM]":"17.1","Tissue RNA - urinary bladder [nTPM]":"17.3","Tissue RNA - vagina [nTPM]":"15.0","Tissue RNA - white matter [nTPM]":"45.2","Cell RNA - A-431 [nTPM]":"36.0","Cell RNA - A549 [nTPM]":"15.7","Cell RNA - AF22 [nTPM]":"28.1","Cell RNA - AN3-CA [nTPM]":"24.3","Cell RNA - ASC diff [nTPM]":"29.8","Cell RNA - ASC TERT1 [nTPM]":"23.6","Cell RNA - BEWO [nTPM]":"35.4","Cell RNA - BJ [nTPM]":"27.9","Cell RNA - BJ hTERT+ [nTPM]":"22.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.2","Cell RNA - CACO-2 [nTPM]":"43.9","Cell RNA - CAPAN-2 [nTPM]":"35.1","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"28.4","Cell RNA - fHDF\/TERT166 [nTPM]":"21.7","Cell RNA - GAMG [nTPM]":"25.3","Cell RNA - HaCaT [nTPM]":"28.1","Cell RNA - HAP1 [nTPM]":"16.3","Cell RNA - HBEC3-KT [nTPM]":"24.4","Cell RNA - HBF TERT88 [nTPM]":"16.0","Cell RNA - HDLM-2 [nTPM]":"31.6","Cell RNA - HEK 293 [nTPM]":"27.4","Cell RNA - HEL [nTPM]":"22.5","Cell RNA - HeLa [nTPM]":"47.9","Cell RNA - Hep G2 [nTPM]":"23.5","Cell RNA - HHSteC [nTPM]":"34.2","Cell RNA - HL-60 [nTPM]":"29.3","Cell RNA - HMC-1 [nTPM]":"20.2","Cell RNA - HSkMC [nTPM]":"29.1","Cell RNA - hTCEpi [nTPM]":"42.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.8","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"32.5","Cell RNA - HUVEC TERT2 [nTPM]":"21.9","Cell RNA - JURKAT [nTPM]":"31.8","Cell RNA - K-562 [nTPM]":"19.6","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"22.3","Cell RNA - MCF7 [nTPM]":"30.0","Cell RNA - MOLT-4 [nTPM]":"23.1","Cell RNA - NB-4 [nTPM]":"48.4","Cell RNA - NTERA-2 [nTPM]":"21.2","Cell RNA - OE19 [nTPM]":"64.4","Cell RNA - PC-3 [nTPM]":"17.2","Cell RNA - REH [nTPM]":"8.2","Cell RNA - RH-30 [nTPM]":"14.4","Cell RNA - RPMI-8226 [nTPM]":"5.9","Cell RNA - RPTEC TERT1 [nTPM]":"30.3","Cell RNA - RT4 [nTPM]":"30.1","Cell RNA - SCLC-21H [nTPM]":"42.5","Cell RNA - SH-SY5Y [nTPM]":"28.6","Cell RNA - SiHa [nTPM]":"16.8","Cell RNA - SK-BR-3 [nTPM]":"75.4","Cell RNA - SK-MEL-30 [nTPM]":"21.6","Cell RNA - SuSa [nTPM]":"18.5","Cell RNA - T-47d [nTPM]":"39.7","Cell RNA - THP-1 [nTPM]":"54.4","Cell RNA - TIME [nTPM]":"25.3","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"14.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"22.4","Cell RNA - U-266\/70 [nTPM]":"25.6","Cell RNA - U-266\/84 [nTPM]":"18.7","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"27.7","Cell RNA - U-937 [nTPM]":"8.7","Cell RNA - WM-115 [nTPM]":"28.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"8.3","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"9.6","Blood RNA - intermediate monocyte [nTPM]":"9.0","Blood RNA - MAIT T-cell [nTPM]":"6.3","Blood RNA - memory B-cell [nTPM]":"8.4","Blood RNA - memory CD4 T-cell [nTPM]":"9.6","Blood RNA - memory CD8 T-cell [nTPM]":"8.9","Blood RNA - myeloid DC [nTPM]":"10.4","Blood RNA - naive B-cell [nTPM]":"8.2","Blood RNA - naive CD4 T-cell [nTPM]":"9.9","Blood RNA - naive CD8 T-cell [nTPM]":"9.1","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"9.2","Blood RNA - non-classical monocyte [nTPM]":"6.5","Blood RNA - plasmacytoid DC [nTPM]":"10.1","Blood RNA - T-reg [nTPM]":"10.5","Blood RNA - total PBMC [nTPM]":"8.3","Brain RNA - amygdala [nTPM]":"44.0","Brain RNA - basal ganglia [nTPM]":"43.7","Brain RNA - cerebellum [nTPM]":"43.6","Brain RNA - cerebral cortex [nTPM]":"46.3","Brain RNA - hippocampal formation [nTPM]":"45.7","Brain RNA - hypothalamus [nTPM]":"42.8","Brain RNA - medulla oblongata [nTPM]":"45.9","Brain RNA - midbrain [nTPM]":"45.0","Brain RNA - pons [nTPM]":"44.5","Brain RNA - spinal cord [nTPM]":"43.9","Brain RNA - thalamus [nTPM]":"46.2","Brain RNA - white matter [nTPM]":"45.2","Single Cell Type RNA - Adipocytes [nTPM]":"9.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"9.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.8","Single Cell Type RNA - dendritic cells [nTPM]":"5.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"15.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"27.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.9","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"24.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NAXE","Gene synonym":["AIBP","APOA1BP","MGC119143","MGC119144","MGC119145","YJEFN1"],"Ensembl":"ENSG00000163382","Gene description":"NAD(P)HX epimerase","Uniprot":["Q8NCW5"],"Chromosome":"1","Position":"156591756-156609507","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted secreted proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Isomerase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"136.7","Distal tubular cells":"201.5","Ductal cells":"112.8","Exocrine glandular cells":"100.1","Proximal tubular cells":"219.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043766","HPA048164"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA043766":"AB_2678660","HPA048164":"AB_2680294"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"47.1","Tissue RNA - adrenal gland [nTPM]":"74.8","Tissue RNA - amygdala [nTPM]":"61.0","Tissue RNA - appendix [nTPM]":"20.9","Tissue RNA - basal ganglia [nTPM]":"63.7","Tissue RNA - bone marrow [nTPM]":"22.2","Tissue RNA - breast [nTPM]":"47.9","Tissue RNA - cerebellum [nTPM]":"66.1","Tissue RNA - cerebral cortex [nTPM]":"69.6","Tissue RNA - cervix [nTPM]":"56.8","Tissue RNA - choroid plexus [nTPM]":"71.1","Tissue RNA - colon [nTPM]":"62.9","Tissue RNA - duodenum [nTPM]":"45.5","Tissue RNA - endometrium 1 [nTPM]":"68.8","Tissue RNA - epididymis [nTPM]":"88.7","Tissue RNA - esophagus [nTPM]":"58.0","Tissue RNA - fallopian tube [nTPM]":"59.5","Tissue RNA - gallbladder [nTPM]":"26.5","Tissue RNA - heart muscle [nTPM]":"111.1","Tissue RNA - hippocampal formation [nTPM]":"60.9","Tissue RNA - hypothalamus [nTPM]":"64.3","Tissue RNA - kidney [nTPM]":"83.8","Tissue RNA - liver [nTPM]":"86.5","Tissue RNA - lung [nTPM]":"43.6","Tissue RNA - lymph node [nTPM]":"27.0","Tissue RNA - medulla oblongata [nTPM]":"62.7","Tissue RNA - midbrain [nTPM]":"64.8","Tissue RNA - ovary [nTPM]":"46.5","Tissue RNA - pancreas [nTPM]":"69.7","Tissue RNA - parathyroid gland [nTPM]":"104.7","Tissue RNA - pituitary gland [nTPM]":"70.0","Tissue RNA - placenta [nTPM]":"23.7","Tissue RNA - pons [nTPM]":"61.8","Tissue RNA - prostate [nTPM]":"62.5","Tissue RNA - rectum [nTPM]":"41.6","Tissue RNA - retina [nTPM]":"17.4","Tissue RNA - salivary gland [nTPM]":"53.9","Tissue RNA - seminal vesicle [nTPM]":"48.3","Tissue RNA - skeletal muscle [nTPM]":"71.8","Tissue RNA - skin 1 [nTPM]":"55.8","Tissue RNA - small intestine [nTPM]":"48.3","Tissue RNA - smooth muscle [nTPM]":"39.7","Tissue RNA - spinal cord [nTPM]":"64.7","Tissue RNA - spleen [nTPM]":"43.2","Tissue RNA - stomach 1 [nTPM]":"67.5","Tissue RNA - testis [nTPM]":"40.8","Tissue RNA - thalamus [nTPM]":"63.5","Tissue RNA - thymus [nTPM]":"30.6","Tissue RNA - thyroid gland [nTPM]":"59.8","Tissue RNA - tongue [nTPM]":"68.2","Tissue RNA - tonsil [nTPM]":"34.3","Tissue RNA - urinary bladder [nTPM]":"55.0","Tissue RNA - vagina [nTPM]":"47.8","Tissue RNA - white matter [nTPM]":"70.5","Cell RNA - A-431 [nTPM]":"114.2","Cell RNA - A549 [nTPM]":"155.4","Cell RNA - AF22 [nTPM]":"43.9","Cell RNA - AN3-CA [nTPM]":"84.4","Cell RNA - ASC diff [nTPM]":"64.0","Cell RNA - ASC TERT1 [nTPM]":"43.8","Cell RNA - BEWO [nTPM]":"55.5","Cell RNA - BJ [nTPM]":"29.5","Cell RNA - BJ hTERT+ [nTPM]":"62.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"69.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"72.6","Cell RNA - CACO-2 [nTPM]":"130.6","Cell RNA - CAPAN-2 [nTPM]":"76.8","Cell RNA - Daudi [nTPM]":"62.4","Cell RNA - EFO-21 [nTPM]":"113.4","Cell RNA - fHDF\/TERT166 [nTPM]":"52.5","Cell RNA - GAMG [nTPM]":"55.9","Cell RNA - HaCaT [nTPM]":"111.1","Cell RNA - HAP1 [nTPM]":"49.4","Cell RNA - HBEC3-KT [nTPM]":"99.0","Cell RNA - HBF TERT88 [nTPM]":"47.5","Cell RNA - HDLM-2 [nTPM]":"81.2","Cell RNA - HEK 293 [nTPM]":"98.5","Cell RNA - HEL [nTPM]":"58.1","Cell RNA - HeLa [nTPM]":"76.2","Cell RNA - Hep G2 [nTPM]":"86.1","Cell RNA - HHSteC [nTPM]":"75.1","Cell RNA - HL-60 [nTPM]":"60.0","Cell RNA - HMC-1 [nTPM]":"60.9","Cell RNA - HSkMC [nTPM]":"44.2","Cell RNA - hTCEpi [nTPM]":"123.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"87.9","Cell RNA - hTERT-HME1 [nTPM]":"81.9","Cell RNA - hTERT-RPE1 [nTPM]":"53.4","Cell RNA - HUVEC TERT2 [nTPM]":"95.4","Cell RNA - JURKAT [nTPM]":"104.7","Cell RNA - K-562 [nTPM]":"54.7","Cell RNA - Karpas-707 [nTPM]":"70.1","Cell RNA - LHCN-M2 [nTPM]":"71.6","Cell RNA - MCF7 [nTPM]":"209.6","Cell RNA - MOLT-4 [nTPM]":"83.3","Cell RNA - NB-4 [nTPM]":"98.0","Cell RNA - NTERA-2 [nTPM]":"43.1","Cell RNA - OE19 [nTPM]":"158.1","Cell RNA - PC-3 [nTPM]":"118.2","Cell RNA - REH [nTPM]":"87.7","Cell RNA - RH-30 [nTPM]":"40.2","Cell RNA - RPMI-8226 [nTPM]":"212.6","Cell RNA - RPTEC TERT1 [nTPM]":"93.0","Cell RNA - RT4 [nTPM]":"93.6","Cell RNA - SCLC-21H [nTPM]":"114.7","Cell RNA - SH-SY5Y [nTPM]":"102.9","Cell RNA - SiHa [nTPM]":"90.4","Cell RNA - SK-BR-3 [nTPM]":"172.4","Cell RNA - SK-MEL-30 [nTPM]":"141.6","Cell RNA - SuSa [nTPM]":"66.4","Cell RNA - T-47d [nTPM]":"178.3","Cell RNA - THP-1 [nTPM]":"117.5","Cell RNA - TIME [nTPM]":"51.1","Cell RNA - U-138 MG [nTPM]":"45.1","Cell RNA - U-2 OS [nTPM]":"64.8","Cell RNA - U-2197 [nTPM]":"64.6","Cell RNA - U-251 MG [nTPM]":"70.6","Cell RNA - U-266\/70 [nTPM]":"180.1","Cell RNA - U-266\/84 [nTPM]":"110.3","Cell RNA - U-698 [nTPM]":"53.0","Cell RNA - U-87 MG [nTPM]":"63.1","Cell RNA - U-937 [nTPM]":"37.0","Cell RNA - WM-115 [nTPM]":"70.4","Blood RNA - basophil [nTPM]":"25.4","Blood RNA - classical monocyte [nTPM]":"96.3","Blood RNA - eosinophil [nTPM]":"52.9","Blood RNA - gdT-cell [nTPM]":"121.2","Blood RNA - intermediate monocyte [nTPM]":"111.3","Blood RNA - MAIT T-cell [nTPM]":"121.3","Blood RNA - memory B-cell [nTPM]":"236.2","Blood RNA - memory CD4 T-cell [nTPM]":"109.4","Blood RNA - memory CD8 T-cell [nTPM]":"124.3","Blood RNA - myeloid DC [nTPM]":"89.1","Blood RNA - naive B-cell [nTPM]":"186.5","Blood RNA - naive CD4 T-cell [nTPM]":"122.8","Blood RNA - naive CD8 T-cell [nTPM]":"114.9","Blood RNA - neutrophil [nTPM]":"11.4","Blood RNA - NK-cell [nTPM]":"141.3","Blood RNA - non-classical monocyte [nTPM]":"89.1","Blood RNA - plasmacytoid DC [nTPM]":"225.7","Blood RNA - T-reg [nTPM]":"110.1","Blood RNA - total PBMC [nTPM]":"186.6","Brain RNA - amygdala [nTPM]":"61.0","Brain RNA - basal ganglia [nTPM]":"63.7","Brain RNA - cerebellum [nTPM]":"66.1","Brain RNA - cerebral cortex [nTPM]":"69.6","Brain RNA - hippocampal formation [nTPM]":"60.9","Brain RNA - hypothalamus [nTPM]":"64.3","Brain RNA - medulla oblongata [nTPM]":"62.7","Brain RNA - midbrain [nTPM]":"64.8","Brain RNA - pons [nTPM]":"61.8","Brain RNA - spinal cord [nTPM]":"64.7","Brain RNA - thalamus [nTPM]":"63.5","Brain RNA - white matter [nTPM]":"70.5","Single Cell Type RNA - Adipocytes [nTPM]":"29.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"14.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"87.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"96.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"23.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"136.7","Single Cell Type RNA - dendritic cells [nTPM]":"28.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"201.5","Single Cell Type RNA - Ductal cells [nTPM]":"112.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.9","Single Cell Type RNA - Endothelial cells [nTPM]":"18.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"100.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.1","Single Cell Type RNA - Fibroblasts [nTPM]":"27.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.0","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"53.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"92.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"19.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"40.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"91.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"219.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"81.3","Single Cell Type RNA - T-cells [nTPM]":"13.4","Single Cell Type RNA - Theca cells [nTPM]":"48.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NDP","Gene synonym":["EVR2","norrin"],"Ensembl":"ENSG00000124479","Gene description":"Norrin cystine knot growth factor NDP","Uniprot":["Q00604"],"Chromosome":"X","Position":"43948776-43973395","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Sensory transduction","Vision","Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.8","ovary":"46.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Granulosa cells":"181.3","Muller glia cells":"105.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"25.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"U-87 MG":"72.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003095"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA003095":"AB_1079457"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"31.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"33.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"3.3","Tissue RNA - cerebellum [nTPM]":"30.9","Tissue RNA - cerebral cortex [nTPM]":"35.8","Tissue RNA - cervix [nTPM]":"20.9","Tissue RNA - choroid plexus [nTPM]":"22.4","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"15.4","Tissue RNA - epididymis [nTPM]":"22.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"20.8","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"31.5","Tissue RNA - hypothalamus [nTPM]":"29.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"30.1","Tissue RNA - midbrain [nTPM]":"33.2","Tissue RNA - ovary [nTPM]":"46.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"31.6","Tissue RNA - prostate [nTPM]":"7.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"19.2","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"13.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"11.4","Tissue RNA - spinal cord [nTPM]":"32.4","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"34.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"32.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.8","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.5","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"1.9","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"4.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"2.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"72.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"31.5","Brain RNA - basal ganglia [nTPM]":"33.4","Brain RNA - cerebellum [nTPM]":"30.9","Brain RNA - cerebral cortex [nTPM]":"35.8","Brain RNA - hippocampal formation [nTPM]":"31.5","Brain RNA - hypothalamus [nTPM]":"29.6","Brain RNA - medulla oblongata [nTPM]":"30.1","Brain RNA - midbrain [nTPM]":"33.2","Brain RNA - pons [nTPM]":"31.6","Brain RNA - spinal cord [nTPM]":"32.4","Brain RNA - thalamus [nTPM]":"34.2","Brain RNA - white matter [nTPM]":"32.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"29.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"181.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"105.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"NDRG1","Gene synonym":["CAP43","DRG1","NDR1","RTP","TDD5"],"Ensembl":"ENSG00000104419","Gene description":"N-myc downstream regulated 1","Uniprot":["Q92597"],"Chromosome":"8","Position":"133237175-133302022","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"613.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"571.9","Distal enterocytes":"405.4","Horizontal cells":"588.9","Suprabasal keratinocytes":"667.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"606.9","hTERT-HME1":"1226.9","U-87 MG":"772.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006881"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Microtubules"],"Antibody RRID":{"HPA006881":"AB_1078392"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"161.2","Tissue RNA - adrenal gland [nTPM]":"72.9","Tissue RNA - amygdala [nTPM]":"299.1","Tissue RNA - appendix [nTPM]":"55.9","Tissue RNA - basal ganglia [nTPM]":"523.6","Tissue RNA - bone marrow [nTPM]":"130.0","Tissue RNA - breast [nTPM]":"107.6","Tissue RNA - cerebellum [nTPM]":"413.5","Tissue RNA - cerebral cortex [nTPM]":"300.2","Tissue RNA - cervix [nTPM]":"169.4","Tissue RNA - choroid plexus [nTPM]":"132.8","Tissue RNA - colon [nTPM]":"130.0","Tissue RNA - duodenum [nTPM]":"242.2","Tissue RNA - endometrium 1 [nTPM]":"92.9","Tissue RNA - epididymis [nTPM]":"34.3","Tissue RNA - esophagus [nTPM]":"343.1","Tissue RNA - fallopian tube [nTPM]":"106.4","Tissue RNA - gallbladder [nTPM]":"87.8","Tissue RNA - heart muscle [nTPM]":"99.8","Tissue RNA - hippocampal formation [nTPM]":"254.5","Tissue RNA - hypothalamus [nTPM]":"316.6","Tissue RNA - kidney [nTPM]":"192.4","Tissue RNA - liver [nTPM]":"49.6","Tissue RNA - lung [nTPM]":"116.6","Tissue RNA - lymph node [nTPM]":"38.7","Tissue RNA - medulla oblongata [nTPM]":"523.2","Tissue RNA - midbrain [nTPM]":"500.0","Tissue RNA - ovary [nTPM]":"126.1","Tissue RNA - pancreas [nTPM]":"52.8","Tissue RNA - parathyroid gland [nTPM]":"69.1","Tissue RNA - pituitary gland [nTPM]":"82.2","Tissue RNA - placenta [nTPM]":"110.8","Tissue RNA - pons [nTPM]":"476.8","Tissue RNA - prostate [nTPM]":"354.3","Tissue RNA - rectum [nTPM]":"77.8","Tissue RNA - retina [nTPM]":"86.0","Tissue RNA - salivary gland [nTPM]":"130.8","Tissue RNA - seminal vesicle [nTPM]":"60.0","Tissue RNA - skeletal muscle [nTPM]":"28.2","Tissue RNA - skin 1 [nTPM]":"262.6","Tissue RNA - small intestine [nTPM]":"258.1","Tissue RNA - smooth muscle [nTPM]":"61.9","Tissue RNA - spinal cord [nTPM]":"333.7","Tissue RNA - spleen [nTPM]":"39.4","Tissue RNA - stomach 1 [nTPM]":"154.0","Tissue RNA - testis [nTPM]":"28.1","Tissue RNA - thalamus [nTPM]":"423.1","Tissue RNA - thymus [nTPM]":"55.1","Tissue RNA - thyroid gland [nTPM]":"80.5","Tissue RNA - tongue [nTPM]":"44.6","Tissue RNA - tonsil [nTPM]":"88.1","Tissue RNA - urinary bladder [nTPM]":"105.5","Tissue RNA - vagina [nTPM]":"273.8","Tissue RNA - white matter [nTPM]":"613.9","Cell RNA - A-431 [nTPM]":"191.6","Cell RNA - A549 [nTPM]":"24.0","Cell RNA - AF22 [nTPM]":"1.7","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"116.3","Cell RNA - ASC TERT1 [nTPM]":"86.8","Cell RNA - BEWO [nTPM]":"26.0","Cell RNA - BJ [nTPM]":"13.7","Cell RNA - BJ hTERT+ [nTPM]":"103.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.5","Cell RNA - CACO-2 [nTPM]":"12.5","Cell RNA - CAPAN-2 [nTPM]":"27.6","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"133.0","Cell RNA - fHDF\/TERT166 [nTPM]":"58.0","Cell RNA - GAMG [nTPM]":"21.9","Cell RNA - HaCaT [nTPM]":"62.4","Cell RNA - HAP1 [nTPM]":"1.7","Cell RNA - HBEC3-KT [nTPM]":"316.8","Cell RNA - HBF TERT88 [nTPM]":"18.0","Cell RNA - HDLM-2 [nTPM]":"13.3","Cell RNA - HEK 293 [nTPM]":"226.8","Cell RNA - HEL [nTPM]":"1.9","Cell RNA - HeLa [nTPM]":"55.6","Cell RNA - Hep G2 [nTPM]":"14.7","Cell RNA - HHSteC [nTPM]":"46.3","Cell RNA - HL-60 [nTPM]":"7.0","Cell RNA - HMC-1 [nTPM]":"4.6","Cell RNA - HSkMC [nTPM]":"79.2","Cell RNA - hTCEpi [nTPM]":"606.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"51.2","Cell RNA - hTERT-HME1 [nTPM]":"1226.9","Cell RNA - hTERT-RPE1 [nTPM]":"124.2","Cell RNA - HUVEC TERT2 [nTPM]":"45.2","Cell RNA - JURKAT [nTPM]":"27.9","Cell RNA - K-562 [nTPM]":"2.0","Cell RNA - Karpas-707 [nTPM]":"138.3","Cell RNA - LHCN-M2 [nTPM]":"17.2","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"19.1","Cell RNA - NB-4 [nTPM]":"20.8","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"69.8","Cell RNA - PC-3 [nTPM]":"155.8","Cell RNA - REH [nTPM]":"1.7","Cell RNA - RH-30 [nTPM]":"19.4","Cell RNA - RPMI-8226 [nTPM]":"86.2","Cell RNA - RPTEC TERT1 [nTPM]":"29.7","Cell RNA - RT4 [nTPM]":"28.0","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"13.0","Cell RNA - SiHa [nTPM]":"31.0","Cell RNA - SK-BR-3 [nTPM]":"312.1","Cell RNA - SK-MEL-30 [nTPM]":"73.3","Cell RNA - SuSa [nTPM]":"48.6","Cell RNA - T-47d [nTPM]":"1.3","Cell RNA - THP-1 [nTPM]":"20.0","Cell RNA - TIME [nTPM]":"58.5","Cell RNA - U-138 MG [nTPM]":"84.4","Cell RNA - U-2 OS [nTPM]":"43.6","Cell RNA - U-2197 [nTPM]":"40.7","Cell RNA - U-251 MG [nTPM]":"10.4","Cell RNA - U-266\/70 [nTPM]":"96.3","Cell RNA - U-266\/84 [nTPM]":"280.3","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"772.5","Cell RNA - U-937 [nTPM]":"69.5","Cell RNA - WM-115 [nTPM]":"161.5","Blood RNA - basophil [nTPM]":"10.9","Blood RNA - classical monocyte [nTPM]":"4.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"5.8","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"9.1","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"5.3","Blood RNA - memory CD8 T-cell [nTPM]":"6.9","Blood RNA - myeloid DC [nTPM]":"6.0","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"4.0","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"4.2","Blood RNA - plasmacytoid DC [nTPM]":"13.0","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"3.7","Brain RNA - amygdala [nTPM]":"299.1","Brain RNA - basal ganglia [nTPM]":"523.6","Brain RNA - cerebellum [nTPM]":"413.5","Brain RNA - cerebral cortex [nTPM]":"300.2","Brain RNA - hippocampal formation [nTPM]":"254.5","Brain RNA - hypothalamus [nTPM]":"316.6","Brain RNA - medulla oblongata [nTPM]":"523.2","Brain RNA - midbrain [nTPM]":"500.0","Brain RNA - pons [nTPM]":"476.8","Brain RNA - spinal cord [nTPM]":"333.7","Brain RNA - thalamus [nTPM]":"423.1","Brain RNA - white matter [nTPM]":"613.9","Single Cell Type RNA - Adipocytes [nTPM]":"123.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"144.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.4","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"23.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"571.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"141.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"207.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.1","Single Cell Type RNA - Bipolar cells [nTPM]":"68.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"80.1","Single Cell Type RNA - Club cells [nTPM]":"102.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"187.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.8","Single Cell Type RNA - dendritic cells [nTPM]":"68.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"405.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"33.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"57.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"59.0","Single Cell Type RNA - Endothelial cells [nTPM]":"217.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.1","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"138.2","Single Cell Type RNA - Fibroblasts [nTPM]":"90.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"151.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"167.7","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"41.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"112.8","Single Cell Type RNA - Hepatocytes [nTPM]":"64.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.5","Single Cell Type RNA - Horizontal cells [nTPM]":"588.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"140.9","Single Cell Type RNA - Ionocytes [nTPM]":"83.4","Single Cell Type RNA - Kupffer cells [nTPM]":"31.1","Single Cell Type RNA - Langerhans cells [nTPM]":"109.5","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"49.0","Single Cell Type RNA - Macrophages [nTPM]":"42.7","Single Cell Type RNA - Melanocytes [nTPM]":"101.4","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"25.7","Single Cell Type RNA - Muller glia cells [nTPM]":"81.2","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"136.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"62.9","Single Cell Type RNA - Paneth cells [nTPM]":"155.9","Single Cell Type RNA - Peritubular cells [nTPM]":"44.0","Single Cell Type RNA - Plasma cells [nTPM]":"23.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"264.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"402.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"87.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.3","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"65.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"113.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"667.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"43.4","Single Cell Type RNA - T-cells [nTPM]":"45.7","Single Cell Type RNA - Theca cells [nTPM]":"32.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"124.7","Single Cell Type RNA - Urothelial cells [nTPM]":"280.8"},{"Gene":"NECAP1","Gene synonym":["DKFZP566B183"],"Ensembl":"ENSG00000089818","Gene description":"NECAP endocytosis associated 1","Uniprot":["Q8NC96"],"Chromosome":"12","Position":"8076939-8097881","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Endocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053980","HPA063300"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA053980":"AB_2682331","HPA063300":"AB_2684981"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"23.7","Tissue RNA - amygdala [nTPM]":"25.4","Tissue RNA - appendix [nTPM]":"11.8","Tissue RNA - basal ganglia [nTPM]":"23.2","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"19.3","Tissue RNA - cerebral cortex [nTPM]":"39.6","Tissue RNA - cervix [nTPM]":"14.9","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"17.8","Tissue RNA - duodenum [nTPM]":"15.6","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"12.1","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"9.9","Tissue RNA - heart muscle [nTPM]":"12.7","Tissue RNA - hippocampal formation [nTPM]":"25.5","Tissue RNA - hypothalamus [nTPM]":"44.0","Tissue RNA - kidney [nTPM]":"15.8","Tissue RNA - liver [nTPM]":"14.4","Tissue RNA - lung [nTPM]":"11.2","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"13.0","Tissue RNA - midbrain [nTPM]":"11.1","Tissue RNA - ovary [nTPM]":"16.1","Tissue RNA - pancreas [nTPM]":"22.3","Tissue RNA - parathyroid gland [nTPM]":"27.5","Tissue RNA - pituitary gland [nTPM]":"24.7","Tissue RNA - placenta [nTPM]":"15.9","Tissue RNA - pons [nTPM]":"17.8","Tissue RNA - prostate [nTPM]":"15.7","Tissue RNA - rectum [nTPM]":"16.9","Tissue RNA - retina [nTPM]":"42.5","Tissue RNA - salivary gland [nTPM]":"15.9","Tissue RNA - seminal vesicle [nTPM]":"12.4","Tissue RNA - skeletal muscle [nTPM]":"7.9","Tissue RNA - skin 1 [nTPM]":"9.4","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"11.4","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"10.1","Tissue RNA - stomach 1 [nTPM]":"16.1","Tissue RNA - testis [nTPM]":"13.6","Tissue RNA - thalamus [nTPM]":"15.2","Tissue RNA - thymus [nTPM]":"14.2","Tissue RNA - thyroid gland [nTPM]":"12.6","Tissue RNA - tongue [nTPM]":"12.2","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"16.9","Tissue RNA - vagina [nTPM]":"10.1","Tissue RNA - white matter [nTPM]":"15.9","Cell RNA - A-431 [nTPM]":"20.4","Cell RNA - A549 [nTPM]":"18.8","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"17.6","Cell RNA - ASC diff [nTPM]":"29.6","Cell RNA - ASC TERT1 [nTPM]":"22.0","Cell RNA - BEWO [nTPM]":"28.2","Cell RNA - BJ [nTPM]":"41.8","Cell RNA - BJ hTERT+ [nTPM]":"26.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"36.2","Cell RNA - CACO-2 [nTPM]":"40.9","Cell RNA - CAPAN-2 [nTPM]":"23.1","Cell RNA - Daudi [nTPM]":"9.2","Cell RNA - EFO-21 [nTPM]":"7.3","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"26.2","Cell RNA - HaCaT [nTPM]":"14.0","Cell RNA - HAP1 [nTPM]":"35.2","Cell RNA - HBEC3-KT [nTPM]":"23.1","Cell RNA - HBF TERT88 [nTPM]":"31.2","Cell RNA - HDLM-2 [nTPM]":"28.2","Cell RNA - HEK 293 [nTPM]":"27.4","Cell RNA - HEL [nTPM]":"11.6","Cell RNA - HeLa [nTPM]":"21.2","Cell RNA - Hep G2 [nTPM]":"21.4","Cell RNA - HHSteC [nTPM]":"26.9","Cell RNA - HL-60 [nTPM]":"10.7","Cell RNA - HMC-1 [nTPM]":"29.2","Cell RNA - HSkMC [nTPM]":"28.7","Cell RNA - hTCEpi [nTPM]":"26.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.4","Cell RNA - hTERT-HME1 [nTPM]":"48.0","Cell RNA - hTERT-RPE1 [nTPM]":"27.7","Cell RNA - HUVEC TERT2 [nTPM]":"26.2","Cell RNA - JURKAT [nTPM]":"15.0","Cell RNA - K-562 [nTPM]":"27.3","Cell RNA - Karpas-707 [nTPM]":"14.8","Cell RNA - LHCN-M2 [nTPM]":"38.8","Cell RNA - MCF7 [nTPM]":"25.8","Cell RNA - MOLT-4 [nTPM]":"17.3","Cell RNA - NB-4 [nTPM]":"2.8","Cell RNA - NTERA-2 [nTPM]":"35.1","Cell RNA - OE19 [nTPM]":"57.2","Cell RNA - PC-3 [nTPM]":"15.4","Cell RNA - REH [nTPM]":"6.8","Cell RNA - RH-30 [nTPM]":"32.0","Cell RNA - RPMI-8226 [nTPM]":"9.7","Cell RNA - RPTEC TERT1 [nTPM]":"24.6","Cell RNA - RT4 [nTPM]":"32.0","Cell RNA - SCLC-21H [nTPM]":"20.7","Cell RNA - SH-SY5Y [nTPM]":"14.3","Cell RNA - SiHa [nTPM]":"21.3","Cell RNA - SK-BR-3 [nTPM]":"29.7","Cell RNA - SK-MEL-30 [nTPM]":"15.9","Cell RNA - SuSa [nTPM]":"40.7","Cell RNA - T-47d [nTPM]":"10.1","Cell RNA - THP-1 [nTPM]":"8.9","Cell RNA - TIME [nTPM]":"26.6","Cell RNA - U-138 MG [nTPM]":"16.9","Cell RNA - U-2 OS [nTPM]":"33.3","Cell RNA - U-2197 [nTPM]":"20.3","Cell RNA - U-251 MG [nTPM]":"30.1","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"18.4","Cell RNA - U-698 [nTPM]":"19.9","Cell RNA - U-87 MG [nTPM]":"30.6","Cell RNA - U-937 [nTPM]":"11.7","Cell RNA - WM-115 [nTPM]":"26.0","Blood RNA - basophil [nTPM]":"28.8","Blood RNA - classical monocyte [nTPM]":"16.6","Blood RNA - eosinophil [nTPM]":"36.4","Blood RNA - gdT-cell [nTPM]":"10.9","Blood RNA - intermediate monocyte [nTPM]":"15.7","Blood RNA - MAIT T-cell [nTPM]":"12.7","Blood RNA - memory B-cell [nTPM]":"9.8","Blood RNA - memory CD4 T-cell [nTPM]":"10.3","Blood RNA - memory CD8 T-cell [nTPM]":"11.2","Blood RNA - myeloid DC [nTPM]":"11.9","Blood RNA - naive B-cell [nTPM]":"10.2","Blood RNA - naive CD4 T-cell [nTPM]":"12.1","Blood RNA - naive CD8 T-cell [nTPM]":"11.0","Blood RNA - neutrophil [nTPM]":"28.7","Blood RNA - NK-cell [nTPM]":"10.6","Blood RNA - non-classical monocyte [nTPM]":"22.7","Blood RNA - plasmacytoid DC [nTPM]":"7.2","Blood RNA - T-reg [nTPM]":"16.8","Blood RNA - total PBMC [nTPM]":"13.0","Brain RNA - amygdala [nTPM]":"25.4","Brain RNA - basal ganglia [nTPM]":"23.2","Brain RNA - cerebellum [nTPM]":"19.3","Brain RNA - cerebral cortex [nTPM]":"39.6","Brain RNA - hippocampal formation [nTPM]":"25.5","Brain RNA - hypothalamus [nTPM]":"44.0","Brain RNA - medulla oblongata [nTPM]":"13.0","Brain RNA - midbrain [nTPM]":"11.1","Brain RNA - pons [nTPM]":"17.8","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"15.2","Brain RNA - white matter [nTPM]":"15.9","Single Cell Type RNA - Adipocytes [nTPM]":"18.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.0","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"36.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"49.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"18.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - dendritic cells [nTPM]":"32.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"15.3","Single Cell Type RNA - Early spermatids [nTPM]":"25.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.9","Single Cell Type RNA - Endothelial cells [nTPM]":"18.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.5","Single Cell Type RNA - Fibroblasts [nTPM]":"17.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.1","Single Cell Type RNA - granulocytes [nTPM]":"29.2","Single Cell Type RNA - Granulosa cells [nTPM]":"33.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"15.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.8","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.1","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.8","Single Cell Type RNA - Langerhans cells [nTPM]":"39.0","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"22.4","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"14.8","Single Cell Type RNA - Muller glia cells [nTPM]":"30.7","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.0","Single Cell Type RNA - Paneth cells [nTPM]":"16.0","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"33.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"46.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.3","Single Cell Type RNA - Spermatocytes [nTPM]":"17.4","Single Cell Type RNA - Spermatogonia [nTPM]":"22.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - T-cells [nTPM]":"35.6","Single Cell Type RNA - Theca cells [nTPM]":"25.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.1","Single Cell Type RNA - Urothelial cells [nTPM]":"22.0"},{"Gene":"NEFH","Gene synonym":["NF-H","NFH"],"Ensembl":"ENSG00000100285","Gene description":"Neurofilament heavy","Uniprot":["P12036"],"Chromosome":"22","Position":"29480218-29491390","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"544.0","prostate":"245.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"20.9","monocytes":"34.6","Prostatic glandular cells":"44.0","Spermatogonia":"29.5","Theca cells":"49.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"prostate cancer":"130.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"4.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"4.7"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SiHa":"182.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"spinal cord":"1241.2"},"Antibody":["CAB007786","HPA061615"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB007786":"AB_598179","HPA061615":"AB_2684568"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"21.1","Tissue RNA - amygdala [nTPM]":"17.7","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"18.9","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"143.1","Tissue RNA - cerebral cortex [nTPM]":"544.0","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"57.3","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"494.1","Tissue RNA - midbrain [nTPM]":"56.2","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"15.4","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"376.1","Tissue RNA - prostate [nTPM]":"245.9","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"39.6","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"58.3","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"7.7","Tissue RNA - thalamus [nTPM]":"172.9","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"1.2","Tissue RNA - white matter [nTPM]":"147.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"3.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"9.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"9.0","Cell RNA - HEK 293 [nTPM]":"34.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"24.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"10.5","Cell RNA - HSkMC [nTPM]":"3.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"28.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"11.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"12.0","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"17.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"19.5","Cell RNA - SiHa [nTPM]":"182.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"5.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"9.9","Cell RNA - TIME [nTPM]":"25.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"17.7","Brain RNA - basal ganglia [nTPM]":"18.9","Brain RNA - cerebellum [nTPM]":"143.1","Brain RNA - cerebral cortex [nTPM]":"544.0","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"57.3","Brain RNA - medulla oblongata [nTPM]":"494.1","Brain RNA - midbrain [nTPM]":"56.2","Brain RNA - pons [nTPM]":"376.1","Brain RNA - spinal cord [nTPM]":"58.3","Brain RNA - thalamus [nTPM]":"172.9","Brain RNA - white matter [nTPM]":"147.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"5.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"34.6","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"29.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"49.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"NEFL","Gene synonym":["CMT1F","CMT2E","NF68","NFL","PPP1R110"],"Ensembl":"ENSG00000277586","Gene description":"Neurofilament light","Uniprot":["P07196"],"Chromosome":"8","Position":"24950955-24956721","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"675.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"32.7","Distal tubular cells":"103.7","Enteroendocrine cells":"33.3","Excitatory neurons":"64.6","Horizontal cells":"30.3","Rod photoreceptor cells":"110.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"24.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory CD4 T-cell":"11.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"113","RNA blood lineage specific nTPM":{"T-cells":"11.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HEK 293":"456.2","PC-3":"145.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014850","HPA015021"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Intermediate filaments","Midbody"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Intermediate filaments"],"Subcellular additional location":["Midbody"],"Antibody RRID":{"HPA014850":"AB_1854397","HPA015021":"AB_2669135"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"35.4","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"36.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"103.6","Tissue RNA - cerebral cortex [nTPM]":"675.9","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.5","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"50.9","Tissue RNA - hypothalamus [nTPM]":"75.6","Tissue RNA - kidney [nTPM]":"5.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"425.7","Tissue RNA - midbrain [nTPM]":"41.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"231.3","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"89.5","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"33.9","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"216.1","Tissue RNA - thymus [nTPM]":"12.7","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"184.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"68.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"29.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"456.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"21.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.0","Cell RNA - HSkMC [nTPM]":"8.3","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"2.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"18.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"145.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"31.7","Cell RNA - RT4 [nTPM]":"4.2","Cell RNA - SCLC-21H [nTPM]":"30.9","Cell RNA - SH-SY5Y [nTPM]":"31.6","Cell RNA - SiHa [nTPM]":"11.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"2.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"2.2","Cell RNA - U-2 OS [nTPM]":"31.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"11.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"35.4","Brain RNA - basal ganglia [nTPM]":"36.7","Brain RNA - cerebellum [nTPM]":"103.6","Brain RNA - cerebral cortex [nTPM]":"675.9","Brain RNA - hippocampal formation [nTPM]":"50.9","Brain RNA - hypothalamus [nTPM]":"75.6","Brain RNA - medulla oblongata [nTPM]":"425.7","Brain RNA - midbrain [nTPM]":"41.1","Brain RNA - pons [nTPM]":"231.3","Brain RNA - spinal cord [nTPM]":"33.9","Brain RNA - thalamus [nTPM]":"216.1","Brain RNA - white matter [nTPM]":"184.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"32.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"103.7","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"64.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"27.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"110.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"13.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NEK2","Gene synonym":["NEK2A","NLK1","PPP1R111","RP67"],"Ensembl":"ENSG00000117650","Gene description":"NIMA related kinase 2","Uniprot":["P51955"],"Chromosome":"1","Position":"211658657-211675630","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Chromosome partition","Meiosis","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"17.9","lymphoid tissue":"19.2","testis":"67.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"76.1","Spermatocytes":"244.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"5.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017530","HPA064967"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm","Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"CAB017530":"AB_1126558","HPA064967":"AB_2685393"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.47e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.11e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"17.9","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"5.9","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"9.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"7.6","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"2.7","Tissue RNA - testis [nTPM]":"67.1","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"19.2","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"10.6","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"86.0","Cell RNA - A549 [nTPM]":"60.5","Cell RNA - AF22 [nTPM]":"45.3","Cell RNA - AN3-CA [nTPM]":"32.6","Cell RNA - ASC diff [nTPM]":"2.6","Cell RNA - ASC TERT1 [nTPM]":"4.5","Cell RNA - BEWO [nTPM]":"49.7","Cell RNA - BJ [nTPM]":"32.4","Cell RNA - BJ hTERT+ [nTPM]":"30.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"55.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.5","Cell RNA - CACO-2 [nTPM]":"32.3","Cell RNA - CAPAN-2 [nTPM]":"81.7","Cell RNA - Daudi [nTPM]":"45.1","Cell RNA - EFO-21 [nTPM]":"15.2","Cell RNA - fHDF\/TERT166 [nTPM]":"25.2","Cell RNA - GAMG [nTPM]":"35.1","Cell RNA - HaCaT [nTPM]":"44.5","Cell RNA - HAP1 [nTPM]":"39.9","Cell RNA - HBEC3-KT [nTPM]":"24.2","Cell RNA - HBF TERT88 [nTPM]":"69.6","Cell RNA - HDLM-2 [nTPM]":"69.5","Cell RNA - HEK 293 [nTPM]":"33.2","Cell RNA - HEL [nTPM]":"21.6","Cell RNA - HeLa [nTPM]":"51.4","Cell RNA - Hep G2 [nTPM]":"44.2","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"43.2","Cell RNA - HMC-1 [nTPM]":"28.3","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"2.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.9","Cell RNA - hTERT-HME1 [nTPM]":"45.9","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"36.3","Cell RNA - JURKAT [nTPM]":"45.2","Cell RNA - K-562 [nTPM]":"59.9","Cell RNA - Karpas-707 [nTPM]":"76.9","Cell RNA - LHCN-M2 [nTPM]":"56.0","Cell RNA - MCF7 [nTPM]":"23.6","Cell RNA - MOLT-4 [nTPM]":"47.3","Cell RNA - NB-4 [nTPM]":"28.8","Cell RNA - NTERA-2 [nTPM]":"43.0","Cell RNA - OE19 [nTPM]":"55.0","Cell RNA - PC-3 [nTPM]":"30.5","Cell RNA - REH [nTPM]":"46.2","Cell RNA - RH-30 [nTPM]":"69.2","Cell RNA - RPMI-8226 [nTPM]":"68.7","Cell RNA - RPTEC TERT1 [nTPM]":"19.7","Cell RNA - RT4 [nTPM]":"24.2","Cell RNA - SCLC-21H [nTPM]":"41.0","Cell RNA - SH-SY5Y [nTPM]":"45.0","Cell RNA - SiHa [nTPM]":"46.6","Cell RNA - SK-BR-3 [nTPM]":"51.5","Cell RNA - SK-MEL-30 [nTPM]":"39.3","Cell RNA - SuSa [nTPM]":"38.4","Cell RNA - T-47d [nTPM]":"79.4","Cell RNA - THP-1 [nTPM]":"25.1","Cell RNA - TIME [nTPM]":"19.0","Cell RNA - U-138 MG [nTPM]":"27.6","Cell RNA - U-2 OS [nTPM]":"54.1","Cell RNA - U-2197 [nTPM]":"54.8","Cell RNA - U-251 MG [nTPM]":"88.3","Cell RNA - U-266\/70 [nTPM]":"31.6","Cell RNA - U-266\/84 [nTPM]":"62.6","Cell RNA - U-698 [nTPM]":"59.6","Cell RNA - U-87 MG [nTPM]":"24.1","Cell RNA - U-937 [nTPM]":"32.6","Cell RNA - WM-115 [nTPM]":"46.8","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"11.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"76.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"39.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"39.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"5.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"244.2","Single Cell Type RNA - Spermatogonia [nTPM]":"26.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"NEUROD2","Gene synonym":["bHLHa1","NDRF"],"Ensembl":"ENSG00000171532","Gene description":"Neuronal differentiation 2","Uniprot":["Q15784"],"Chromosome":"17","Position":"39603536-39609777","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"81","RNA tissue specific nTPM":{"brain":"94.7","choroid plexus":"37.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"10.1","Cone photoreceptor cells":"4.2","Enteroendocrine cells":"23.8","Excitatory neurons":"14.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"0.7","glioma":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"139","RNA cell line specific nTPM":{"SCLC-21H":"29.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"68.0","hippocampal formation":"76.9"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"53.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"58.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"74.5","Tissue RNA - cerebral cortex [nTPM]":"94.7","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"37.3","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"73.9","Tissue RNA - hypothalamus [nTPM]":"37.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"56.0","Tissue RNA - midbrain [nTPM]":"38.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"55.8","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"38.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"37.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"58.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"29.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"53.0","Brain RNA - basal ganglia [nTPM]":"58.9","Brain RNA - cerebellum [nTPM]":"74.5","Brain RNA - cerebral cortex [nTPM]":"94.7","Brain RNA - hippocampal formation [nTPM]":"73.9","Brain RNA - hypothalamus [nTPM]":"37.2","Brain RNA - medulla oblongata [nTPM]":"56.0","Brain RNA - midbrain [nTPM]":"38.1","Brain RNA - pons [nTPM]":"55.8","Brain RNA - spinal cord [nTPM]":"38.5","Brain RNA - thalamus [nTPM]":"37.2","Brain RNA - white matter [nTPM]":"58.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"NGF","Gene synonym":["NGFB"],"Ensembl":"ENSG00000134259","Gene description":"Nerve growth factor","Uniprot":["P01138"],"Chromosome":"1","Position":"115285904-115338770","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor","Metalloenzyme inhibitor","Metalloprotease inhibitor","Protease inhibitor"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"20.8","ovary":"18.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"15.7","Leydig cells":"29.2","Sertoli cells":"118.3","Smooth muscle cells":"51.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"4.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"87.9","BJ hTERT+ SV40 Large T+":"30.1","GAMG":"46.2","hTEC\/SVTERT24-B":"29.8","hTERT-RPE1":"49.0","U-2197":"60.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":40000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.80e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-4"},"Tissue RNA - adipose tissue [nTPM]":"13.9","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"2.1","Tissue RNA - colon [nTPM]":"5.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"13.2","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"20.8","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"4.0","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"18.9","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"2.6","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"2.1","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"3.7","Tissue RNA - stomach 1 [nTPM]":"2.1","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.8","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"87.9","Cell RNA - BJ hTERT+ [nTPM]":"9.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.9","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.9","Cell RNA - fHDF\/TERT166 [nTPM]":"21.1","Cell RNA - GAMG [nTPM]":"46.2","Cell RNA - HaCaT [nTPM]":"3.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"13.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"12.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.8","Cell RNA - hTERT-HME1 [nTPM]":"21.6","Cell RNA - hTERT-RPE1 [nTPM]":"49.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"1.8","Cell RNA - U-2 OS [nTPM]":"3.7","Cell RNA - U-2197 [nTPM]":"60.0","Cell RNA - U-251 MG [nTPM]":"3.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"19.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"7.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"29.2","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"118.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"NHLRC1","Gene synonym":["bA204B7.2","EPM2B"],"Ensembl":"ENSG00000187566","Gene description":"NHL repeat containing E3 ubiquitin protein ligase 1","Uniprot":["Q6VVB1"],"Chromosome":"6","Position":"18120440-18122677","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"5.0","Exocrine glandular cells":"3.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"6.8","K-562":"6.1","SCLC-21H":"6.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066030"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA066030":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.01e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.30e-4"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"1.5","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"4.1","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"2.6","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"1.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.6","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"2.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.7","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"2.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"2.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.0","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"2.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"6.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"2.8","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"5.3","Cell RNA - SK-BR-3 [nTPM]":"4.3","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"3.1","Cell RNA - THP-1 [nTPM]":"1.7","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"4.4","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"4.7","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"NHS","Gene synonym":[],"Ensembl":"ENSG00000188158","Gene description":"NHS actin remodeling regulator","Uniprot":["Q6T4R5"],"Chromosome":"X","Position":"17375200-17735994","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Inhibitory neurons":"264.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"12.7","RPTEC TERT1":"19.2","RT4":"12.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031497","HPA076257"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA031497":"AB_10610144","HPA076257":"AB_2686789"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.68e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.2","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"6.1","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"4.1","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"1.8","Tissue RNA - fallopian tube [nTPM]":"2.7","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"3.5","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"2.0","Tissue RNA - seminal vesicle [nTPM]":"2.7","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"1.5","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"7.9","Cell RNA - A549 [nTPM]":"3.1","Cell RNA - AF22 [nTPM]":"5.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"8.7","Cell RNA - BJ [nTPM]":"3.5","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"7.5","Cell RNA - HaCaT [nTPM]":"6.8","Cell RNA - HAP1 [nTPM]":"3.5","Cell RNA - HBEC3-KT [nTPM]":"4.4","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"5.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"3.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"6.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"3.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"6.7","Cell RNA - OE19 [nTPM]":"3.6","Cell RNA - PC-3 [nTPM]":"2.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"19.2","Cell RNA - RT4 [nTPM]":"12.0","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"2.8","Cell RNA - SiHa [nTPM]":"9.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"8.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"8.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"11.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"14.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.4","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.4","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"264.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"5.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.8","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"31.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"4.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"12.8"},{"Gene":"NIPA1","Gene synonym":["MGC35570","SLC57A1","SPG6"],"Ensembl":"ENSG00000170113","Gene description":"NIPA magnesium transporter 1","Uniprot":["Q7RTP0"],"Chromosome":"15","Position":"22773063-22829789","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"40.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"36.2","Inhibitory neurons":"33.8","Oligodendrocytes":"65.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"3.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023269"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023269":"AB_1854485"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"27.7","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"36.9","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"36.8","Tissue RNA - cerebral cortex [nTPM]":"38.1","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"17.9","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"4.3","Tissue RNA - fallopian tube [nTPM]":"2.5","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"3.5","Tissue RNA - hippocampal formation [nTPM]":"22.8","Tissue RNA - hypothalamus [nTPM]":"28.7","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"35.4","Tissue RNA - midbrain [nTPM]":"36.9","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"8.7","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"33.8","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"6.2","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"36.1","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"36.0","Tissue RNA - thymus [nTPM]":"8.2","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"5.5","Tissue RNA - urinary bladder [nTPM]":"3.2","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"40.2","Cell RNA - A-431 [nTPM]":"14.9","Cell RNA - A549 [nTPM]":"17.4","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"12.4","Cell RNA - ASC diff [nTPM]":"6.9","Cell RNA - ASC TERT1 [nTPM]":"5.6","Cell RNA - BEWO [nTPM]":"3.8","Cell RNA - BJ [nTPM]":"17.6","Cell RNA - BJ hTERT+ [nTPM]":"12.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.1","Cell RNA - CACO-2 [nTPM]":"13.3","Cell RNA - CAPAN-2 [nTPM]":"7.4","Cell RNA - Daudi [nTPM]":"6.9","Cell RNA - EFO-21 [nTPM]":"13.5","Cell RNA - fHDF\/TERT166 [nTPM]":"7.3","Cell RNA - GAMG [nTPM]":"17.4","Cell RNA - HaCaT [nTPM]":"9.7","Cell RNA - HAP1 [nTPM]":"16.0","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"10.1","Cell RNA - HDLM-2 [nTPM]":"40.2","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"10.8","Cell RNA - HeLa [nTPM]":"10.8","Cell RNA - Hep G2 [nTPM]":"11.4","Cell RNA - HHSteC [nTPM]":"8.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"20.8","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"15.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.5","Cell RNA - hTERT-HME1 [nTPM]":"9.2","Cell RNA - hTERT-RPE1 [nTPM]":"13.6","Cell RNA - HUVEC TERT2 [nTPM]":"8.2","Cell RNA - JURKAT [nTPM]":"15.2","Cell RNA - K-562 [nTPM]":"8.4","Cell RNA - Karpas-707 [nTPM]":"11.3","Cell RNA - LHCN-M2 [nTPM]":"4.8","Cell RNA - MCF7 [nTPM]":"5.6","Cell RNA - MOLT-4 [nTPM]":"5.9","Cell RNA - NB-4 [nTPM]":"9.7","Cell RNA - NTERA-2 [nTPM]":"5.9","Cell RNA - OE19 [nTPM]":"15.9","Cell RNA - PC-3 [nTPM]":"18.2","Cell RNA - REH [nTPM]":"12.1","Cell RNA - RH-30 [nTPM]":"7.7","Cell RNA - RPMI-8226 [nTPM]":"5.4","Cell RNA - RPTEC TERT1 [nTPM]":"13.0","Cell RNA - RT4 [nTPM]":"14.9","Cell RNA - SCLC-21H [nTPM]":"15.2","Cell RNA - SH-SY5Y [nTPM]":"15.4","Cell RNA - SiHa [nTPM]":"13.2","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"16.7","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"10.3","Cell RNA - THP-1 [nTPM]":"13.8","Cell RNA - TIME [nTPM]":"15.4","Cell RNA - U-138 MG [nTPM]":"23.9","Cell RNA - U-2 OS [nTPM]":"12.2","Cell RNA - U-2197 [nTPM]":"10.1","Cell RNA - U-251 MG [nTPM]":"27.2","Cell RNA - U-266\/70 [nTPM]":"12.7","Cell RNA - U-266\/84 [nTPM]":"13.6","Cell RNA - U-698 [nTPM]":"12.4","Cell RNA - U-87 MG [nTPM]":"12.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"15.6","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"27.7","Brain RNA - basal ganglia [nTPM]":"36.9","Brain RNA - cerebellum [nTPM]":"36.8","Brain RNA - cerebral cortex [nTPM]":"38.1","Brain RNA - hippocampal formation [nTPM]":"22.8","Brain RNA - hypothalamus [nTPM]":"28.7","Brain RNA - medulla oblongata [nTPM]":"35.4","Brain RNA - midbrain [nTPM]":"36.9","Brain RNA - pons [nTPM]":"33.8","Brain RNA - spinal cord [nTPM]":"36.1","Brain RNA - thalamus [nTPM]":"36.0","Brain RNA - white matter [nTPM]":"40.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.9","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"7.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"5.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - dendritic cells [nTPM]":"10.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.4","Single Cell Type RNA - Endothelial cells [nTPM]":"5.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"6.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"3.8","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"65.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.7","Single Cell Type RNA - Paneth cells [nTPM]":"6.8","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"8.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"7.3"},{"Gene":"NMNAT1","Gene synonym":["LCA9","NMNAT","PNAT1"],"Ensembl":"ENSG00000173614","Gene description":"Nicotinamide nucleotide adenylyltransferase 1","Uniprot":["Q9HAN9"],"Chromosome":"1","Position":"9943428-9985501","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pyridine nucleotide biosynthesis"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059447"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA059447":"AB_2684022"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.85e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"2.5","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"9.0","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"5.8","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"10.7","Tissue RNA - hippocampal formation [nTPM]":"5.1","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"8.2","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"4.5","Tissue RNA - rectum [nTPM]":"9.0","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"23.3","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"6.1","Tissue RNA - smooth muscle [nTPM]":"5.0","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"16.9","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"7.2","Cell RNA - A-431 [nTPM]":"4.6","Cell RNA - A549 [nTPM]":"5.4","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"13.4","Cell RNA - ASC TERT1 [nTPM]":"12.2","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"9.1","Cell RNA - BJ hTERT+ [nTPM]":"7.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.7","Cell RNA - CACO-2 [nTPM]":"2.4","Cell RNA - CAPAN-2 [nTPM]":"7.7","Cell RNA - Daudi [nTPM]":"4.8","Cell RNA - EFO-21 [nTPM]":"5.7","Cell RNA - fHDF\/TERT166 [nTPM]":"12.9","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"4.6","Cell RNA - HAP1 [nTPM]":"9.4","Cell RNA - HBEC3-KT [nTPM]":"12.4","Cell RNA - HBF TERT88 [nTPM]":"11.0","Cell RNA - HDLM-2 [nTPM]":"10.4","Cell RNA - HEK 293 [nTPM]":"4.8","Cell RNA - HEL [nTPM]":"7.6","Cell RNA - HeLa [nTPM]":"3.0","Cell RNA - Hep G2 [nTPM]":"7.6","Cell RNA - HHSteC [nTPM]":"11.4","Cell RNA - HL-60 [nTPM]":"6.7","Cell RNA - HMC-1 [nTPM]":"7.7","Cell RNA - HSkMC [nTPM]":"13.3","Cell RNA - hTCEpi [nTPM]":"14.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.1","Cell RNA - hTERT-HME1 [nTPM]":"17.4","Cell RNA - hTERT-RPE1 [nTPM]":"9.5","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"10.4","Cell RNA - K-562 [nTPM]":"9.7","Cell RNA - Karpas-707 [nTPM]":"3.1","Cell RNA - LHCN-M2 [nTPM]":"10.9","Cell RNA - MCF7 [nTPM]":"8.0","Cell RNA - MOLT-4 [nTPM]":"3.8","Cell RNA - NB-4 [nTPM]":"4.4","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"10.2","Cell RNA - PC-3 [nTPM]":"10.2","Cell RNA - REH [nTPM]":"4.2","Cell RNA - RH-30 [nTPM]":"4.7","Cell RNA - RPMI-8226 [nTPM]":"2.7","Cell RNA - RPTEC TERT1 [nTPM]":"11.9","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"2.8","Cell RNA - SiHa [nTPM]":"11.8","Cell RNA - SK-BR-3 [nTPM]":"9.7","Cell RNA - SK-MEL-30 [nTPM]":"10.4","Cell RNA - SuSa [nTPM]":"3.8","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"7.2","Cell RNA - TIME [nTPM]":"10.2","Cell RNA - U-138 MG [nTPM]":"4.1","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"8.7","Cell RNA - U-251 MG [nTPM]":"4.2","Cell RNA - U-266\/70 [nTPM]":"4.5","Cell RNA - U-266\/84 [nTPM]":"4.3","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"7.1","Cell RNA - U-937 [nTPM]":"13.8","Cell RNA - WM-115 [nTPM]":"8.6","Blood RNA - basophil [nTPM]":"7.5","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"3.3","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"9.1","Blood RNA - NK-cell [nTPM]":"2.5","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"3.2","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"5.1","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"7.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"3.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"7.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"9.1","Single Cell Type RNA - Early spermatids [nTPM]":"7.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.7","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.1","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"9.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"9.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.9","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"13.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.6","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.0","Single Cell Type RNA - Paneth cells [nTPM]":"6.2","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"17.3","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"13.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.5","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"NOP56","Gene synonym":["NOL5A","SCA36"],"Ensembl":"ENSG00000101361","Gene description":"NOP56 ribonucleoprotein","Uniprot":["O00567"],"Chromosome":"20","Position":"2652593-2658393","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis"],"Molecular function":["Ribonucleoprotein"],"Disease involvement":["Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049918","CAB075757"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"CAB075757":"AB_2665763","HPA049918":"AB_2680952"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.77e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Tissue RNA - adipose tissue [nTPM]":"41.4","Tissue RNA - adrenal gland [nTPM]":"31.3","Tissue RNA - amygdala [nTPM]":"39.9","Tissue RNA - appendix [nTPM]":"42.6","Tissue RNA - basal ganglia [nTPM]":"39.7","Tissue RNA - bone marrow [nTPM]":"60.4","Tissue RNA - breast [nTPM]":"37.1","Tissue RNA - cerebellum [nTPM]":"38.8","Tissue RNA - cerebral cortex [nTPM]":"59.7","Tissue RNA - cervix [nTPM]":"30.9","Tissue RNA - choroid plexus [nTPM]":"35.3","Tissue RNA - colon [nTPM]":"33.8","Tissue RNA - duodenum [nTPM]":"28.8","Tissue RNA - endometrium 1 [nTPM]":"39.9","Tissue RNA - epididymis [nTPM]":"34.7","Tissue RNA - esophagus [nTPM]":"37.1","Tissue RNA - fallopian tube [nTPM]":"50.7","Tissue RNA - gallbladder [nTPM]":"26.3","Tissue RNA - heart muscle [nTPM]":"30.9","Tissue RNA - hippocampal formation [nTPM]":"41.1","Tissue RNA - hypothalamus [nTPM]":"45.8","Tissue RNA - kidney [nTPM]":"29.8","Tissue RNA - liver [nTPM]":"30.5","Tissue RNA - lung [nTPM]":"25.9","Tissue RNA - lymph node [nTPM]":"53.5","Tissue RNA - medulla oblongata [nTPM]":"40.4","Tissue RNA - midbrain [nTPM]":"40.6","Tissue RNA - ovary [nTPM]":"49.7","Tissue RNA - pancreas [nTPM]":"38.6","Tissue RNA - parathyroid gland [nTPM]":"27.1","Tissue RNA - pituitary gland [nTPM]":"31.5","Tissue RNA - placenta [nTPM]":"37.4","Tissue RNA - pons [nTPM]":"43.4","Tissue RNA - prostate [nTPM]":"31.1","Tissue RNA - rectum [nTPM]":"39.9","Tissue RNA - retina [nTPM]":"21.0","Tissue RNA - salivary gland [nTPM]":"27.1","Tissue RNA - seminal vesicle [nTPM]":"35.6","Tissue RNA - skeletal muscle [nTPM]":"43.2","Tissue RNA - skin 1 [nTPM]":"38.4","Tissue RNA - small intestine [nTPM]":"28.1","Tissue RNA - smooth muscle [nTPM]":"52.0","Tissue RNA - spinal cord [nTPM]":"39.9","Tissue RNA - spleen [nTPM]":"37.7","Tissue RNA - stomach 1 [nTPM]":"25.9","Tissue RNA - testis [nTPM]":"28.3","Tissue RNA - thalamus [nTPM]":"45.4","Tissue RNA - thymus [nTPM]":"51.9","Tissue RNA - thyroid gland [nTPM]":"33.4","Tissue RNA - tongue [nTPM]":"29.2","Tissue RNA - tonsil [nTPM]":"62.2","Tissue RNA - urinary bladder [nTPM]":"52.4","Tissue RNA - vagina [nTPM]":"28.4","Tissue RNA - white matter [nTPM]":"44.4","Cell RNA - A-431 [nTPM]":"152.8","Cell RNA - A549 [nTPM]":"147.3","Cell RNA - AF22 [nTPM]":"108.4","Cell RNA - AN3-CA [nTPM]":"108.0","Cell RNA - ASC diff [nTPM]":"122.8","Cell RNA - ASC TERT1 [nTPM]":"89.8","Cell RNA - BEWO [nTPM]":"184.2","Cell RNA - BJ [nTPM]":"150.4","Cell RNA - BJ hTERT+ [nTPM]":"97.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"198.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"134.9","Cell RNA - CACO-2 [nTPM]":"204.3","Cell RNA - CAPAN-2 [nTPM]":"122.2","Cell RNA - Daudi [nTPM]":"330.5","Cell RNA - EFO-21 [nTPM]":"82.7","Cell RNA - fHDF\/TERT166 [nTPM]":"104.2","Cell RNA - GAMG [nTPM]":"117.7","Cell RNA - HaCaT [nTPM]":"253.3","Cell RNA - HAP1 [nTPM]":"287.5","Cell RNA - HBEC3-KT [nTPM]":"221.4","Cell RNA - HBF TERT88 [nTPM]":"196.6","Cell RNA - HDLM-2 [nTPM]":"93.5","Cell RNA - HEK 293 [nTPM]":"171.4","Cell RNA - HEL [nTPM]":"195.0","Cell RNA - HeLa [nTPM]":"76.0","Cell RNA - Hep G2 [nTPM]":"225.3","Cell RNA - HHSteC [nTPM]":"125.9","Cell RNA - HL-60 [nTPM]":"179.4","Cell RNA - HMC-1 [nTPM]":"91.3","Cell RNA - HSkMC [nTPM]":"123.6","Cell RNA - hTCEpi [nTPM]":"137.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"254.8","Cell RNA - hTERT-HME1 [nTPM]":"260.4","Cell RNA - hTERT-RPE1 [nTPM]":"78.2","Cell RNA - HUVEC TERT2 [nTPM]":"117.4","Cell RNA - JURKAT [nTPM]":"153.1","Cell RNA - K-562 [nTPM]":"215.7","Cell RNA - Karpas-707 [nTPM]":"151.2","Cell RNA - LHCN-M2 [nTPM]":"138.1","Cell RNA - MCF7 [nTPM]":"103.1","Cell RNA - MOLT-4 [nTPM]":"317.8","Cell RNA - NB-4 [nTPM]":"214.1","Cell RNA - NTERA-2 [nTPM]":"233.8","Cell RNA - OE19 [nTPM]":"270.9","Cell RNA - PC-3 [nTPM]":"180.9","Cell RNA - REH [nTPM]":"257.2","Cell RNA - RH-30 [nTPM]":"156.2","Cell RNA - RPMI-8226 [nTPM]":"188.5","Cell RNA - RPTEC TERT1 [nTPM]":"120.8","Cell RNA - RT4 [nTPM]":"146.7","Cell RNA - SCLC-21H [nTPM]":"115.5","Cell RNA - SH-SY5Y [nTPM]":"101.1","Cell RNA - SiHa [nTPM]":"171.0","Cell RNA - SK-BR-3 [nTPM]":"193.4","Cell RNA - SK-MEL-30 [nTPM]":"302.8","Cell RNA - SuSa [nTPM]":"115.7","Cell RNA - T-47d [nTPM]":"167.6","Cell RNA - THP-1 [nTPM]":"152.7","Cell RNA - TIME [nTPM]":"91.6","Cell RNA - U-138 MG [nTPM]":"170.2","Cell RNA - U-2 OS [nTPM]":"115.9","Cell RNA - U-2197 [nTPM]":"132.6","Cell RNA - U-251 MG [nTPM]":"227.2","Cell RNA - U-266\/70 [nTPM]":"91.9","Cell RNA - U-266\/84 [nTPM]":"186.0","Cell RNA - U-698 [nTPM]":"274.0","Cell RNA - U-87 MG [nTPM]":"45.9","Cell RNA - U-937 [nTPM]":"209.4","Cell RNA - WM-115 [nTPM]":"128.5","Blood RNA - basophil [nTPM]":"5.1","Blood RNA - classical monocyte [nTPM]":"23.2","Blood RNA - eosinophil [nTPM]":"18.9","Blood RNA - gdT-cell [nTPM]":"33.0","Blood RNA - intermediate monocyte [nTPM]":"26.4","Blood RNA - MAIT T-cell [nTPM]":"41.1","Blood RNA - memory B-cell [nTPM]":"35.8","Blood RNA - memory CD4 T-cell [nTPM]":"35.9","Blood RNA - memory CD8 T-cell [nTPM]":"36.6","Blood RNA - myeloid DC [nTPM]":"23.6","Blood RNA - naive B-cell [nTPM]":"32.4","Blood RNA - naive CD4 T-cell [nTPM]":"34.0","Blood RNA - naive CD8 T-cell [nTPM]":"34.0","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"33.6","Blood RNA - non-classical monocyte [nTPM]":"19.8","Blood RNA - plasmacytoid DC [nTPM]":"41.1","Blood RNA - T-reg [nTPM]":"33.4","Blood RNA - total PBMC [nTPM]":"24.8","Brain RNA - amygdala [nTPM]":"39.9","Brain RNA - basal ganglia [nTPM]":"39.7","Brain RNA - cerebellum [nTPM]":"38.8","Brain RNA - cerebral cortex [nTPM]":"59.7","Brain RNA - hippocampal formation [nTPM]":"41.1","Brain RNA - hypothalamus [nTPM]":"45.8","Brain RNA - medulla oblongata [nTPM]":"40.4","Brain RNA - midbrain [nTPM]":"40.6","Brain RNA - pons [nTPM]":"43.4","Brain RNA - spinal cord [nTPM]":"39.9","Brain RNA - thalamus [nTPM]":"45.4","Brain RNA - white matter [nTPM]":"44.4","Single Cell Type RNA - Adipocytes [nTPM]":"75.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"59.8","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"89.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"96.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"103.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"76.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"88.2","Single Cell Type RNA - Bipolar cells [nTPM]":"39.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"62.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"78.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"100.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"117.5","Single Cell Type RNA - dendritic cells [nTPM]":"132.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"71.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"78.2","Single Cell Type RNA - Early spermatids [nTPM]":"8.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"64.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"100.6","Single Cell Type RNA - Endothelial cells [nTPM]":"73.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"72.3","Single Cell Type RNA - Erythroid cells [nTPM]":"93.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"86.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"124.2","Single Cell Type RNA - Fibroblasts [nTPM]":"87.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.5","Single Cell Type RNA - granulocytes [nTPM]":"79.1","Single Cell Type RNA - Granulosa cells [nTPM]":"97.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"52.5","Single Cell Type RNA - Hepatocytes [nTPM]":"40.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"86.9","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"81.2","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"46.8","Single Cell Type RNA - Langerhans cells [nTPM]":"45.9","Single Cell Type RNA - Late spermatids [nTPM]":"14.0","Single Cell Type RNA - Leydig cells [nTPM]":"57.2","Single Cell Type RNA - Macrophages [nTPM]":"57.5","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"64.9","Single Cell Type RNA - Muller glia cells [nTPM]":"32.8","Single Cell Type RNA - NK-cells [nTPM]":"80.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"75.6","Single Cell Type RNA - Paneth cells [nTPM]":"34.6","Single Cell Type RNA - Peritubular cells [nTPM]":"54.9","Single Cell Type RNA - Plasma cells [nTPM]":"79.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"92.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"53.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"81.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"110.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"141.5","Single Cell Type RNA - Spermatocytes [nTPM]":"50.3","Single Cell Type RNA - Spermatogonia [nTPM]":"185.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"89.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"81.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"56.5","Single Cell Type RNA - T-cells [nTPM]":"102.6","Single Cell Type RNA - Theca cells [nTPM]":"99.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"110.0","Single Cell Type RNA - Urothelial cells [nTPM]":"58.0"},{"Gene":"NOTCH2NLC","Gene synonym":[],"Ensembl":"ENSG00000286219","Gene description":"Notch 2 N-terminal like C","Uniprot":["P0DPK4"],"Chromosome":"1","Position":"149390614-149468030","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Notch signaling pathway"],"Molecular function":null,"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"74.2","U-266\/70":"121.3"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"9.6","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"18.0","Tissue RNA - breast [nTPM]":"12.1","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"16.4","Tissue RNA - cervix [nTPM]":"13.2","Tissue RNA - choroid plexus [nTPM]":"14.5","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"3.5","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"9.8","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"6.9","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"21.6","Tissue RNA - lung [nTPM]":"6.1","Tissue RNA - lymph node [nTPM]":"8.3","Tissue RNA - medulla oblongata [nTPM]":"10.0","Tissue RNA - midbrain [nTPM]":"9.0","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"7.6","Tissue RNA - pituitary gland [nTPM]":null,"Tissue RNA - placenta [nTPM]":"5.6","Tissue RNA - pons [nTPM]":"8.1","Tissue RNA - prostate [nTPM]":"9.5","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"14.3","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"12.7","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"5.2","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"7.3","Tissue RNA - stomach 1 [nTPM]":"3.1","Tissue RNA - testis [nTPM]":"20.8","Tissue RNA - thalamus [nTPM]":"10.6","Tissue RNA - thymus [nTPM]":"7.4","Tissue RNA - thyroid gland [nTPM]":"6.1","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"8.4","Tissue RNA - vagina [nTPM]":null,"Tissue RNA - white matter [nTPM]":"8.8","Cell RNA - A-431 [nTPM]":"14.2","Cell RNA - A549 [nTPM]":"6.0","Cell RNA - AF22 [nTPM]":"4.0","Cell RNA - AN3-CA [nTPM]":"5.0","Cell RNA - ASC diff [nTPM]":"9.0","Cell RNA - ASC TERT1 [nTPM]":"11.1","Cell RNA - BEWO [nTPM]":"2.5","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"39.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.8","Cell RNA - CACO-2 [nTPM]":"3.6","Cell RNA - CAPAN-2 [nTPM]":"12.2","Cell RNA - Daudi [nTPM]":"2.2","Cell RNA - EFO-21 [nTPM]":"3.6","Cell RNA - fHDF\/TERT166 [nTPM]":"17.1","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"5.0","Cell RNA - HAP1 [nTPM]":"5.1","Cell RNA - HBEC3-KT [nTPM]":"19.7","Cell RNA - HBF TERT88 [nTPM]":"10.8","Cell RNA - HDLM-2 [nTPM]":"7.1","Cell RNA - HEK 293 [nTPM]":"3.4","Cell RNA - HEL [nTPM]":"11.7","Cell RNA - HeLa [nTPM]":"43.8","Cell RNA - Hep G2 [nTPM]":"1.8","Cell RNA - HHSteC [nTPM]":"37.9","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"33.5","Cell RNA - hTCEpi [nTPM]":"8.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.3","Cell RNA - hTERT-HME1 [nTPM]":"74.2","Cell RNA - hTERT-RPE1 [nTPM]":"10.7","Cell RNA - HUVEC TERT2 [nTPM]":"14.4","Cell RNA - JURKAT [nTPM]":"8.3","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"50.7","Cell RNA - LHCN-M2 [nTPM]":"17.0","Cell RNA - MCF7 [nTPM]":"29.8","Cell RNA - MOLT-4 [nTPM]":"5.1","Cell RNA - NB-4 [nTPM]":"7.7","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"8.6","Cell RNA - PC-3 [nTPM]":"13.6","Cell RNA - REH [nTPM]":"4.8","Cell RNA - RH-30 [nTPM]":"7.9","Cell RNA - RPMI-8226 [nTPM]":"27.3","Cell RNA - RPTEC TERT1 [nTPM]":"17.9","Cell RNA - RT4 [nTPM]":"16.4","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"12.9","Cell RNA - SK-BR-3 [nTPM]":"12.3","Cell RNA - SK-MEL-30 [nTPM]":"2.0","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"10.6","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"12.8","Cell RNA - U-138 MG [nTPM]":"5.4","Cell RNA - U-2 OS [nTPM]":"8.8","Cell RNA - U-2197 [nTPM]":"9.5","Cell RNA - U-251 MG [nTPM]":"9.8","Cell RNA - U-266\/70 [nTPM]":"121.3","Cell RNA - U-266\/84 [nTPM]":"35.9","Cell RNA - U-698 [nTPM]":"7.6","Cell RNA - U-87 MG [nTPM]":"11.9","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"8.0","Blood RNA - basophil [nTPM]":"17.8","Blood RNA - classical monocyte [nTPM]":"29.3","Blood RNA - eosinophil [nTPM]":"47.3","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"21.4","Blood RNA - MAIT T-cell [nTPM]":"5.0","Blood RNA - memory B-cell [nTPM]":"57.7","Blood RNA - memory CD4 T-cell [nTPM]":"5.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.8","Blood RNA - myeloid DC [nTPM]":"44.3","Blood RNA - naive B-cell [nTPM]":"26.6","Blood RNA - naive CD4 T-cell [nTPM]":"5.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"14.1","Blood RNA - NK-cell [nTPM]":"8.3","Blood RNA - non-classical monocyte [nTPM]":"18.9","Blood RNA - plasmacytoid DC [nTPM]":"23.6","Blood RNA - T-reg [nTPM]":"8.2","Blood RNA - total PBMC [nTPM]":"11.3","Brain RNA - amygdala [nTPM]":"9.6","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"16.4","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"10.0","Brain RNA - midbrain [nTPM]":"9.0","Brain RNA - pons [nTPM]":"8.1","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"10.6","Brain RNA - white matter [nTPM]":"8.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NPRL2","Gene synonym":["NPR2","NPR2L","TUSC4"],"Ensembl":"ENSG00000114388","Gene description":"NPR2 like, GATOR1 complex subunit","Uniprot":["Q8WTW4"],"Chromosome":"3","Position":"50347330-50350826","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"94.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038196","HPA038197"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038196":"AB_10675631","HPA038197":"AB_10671523"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"9.2","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"5.1","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"10.0","Tissue RNA - cerebral cortex [nTPM]":"11.0","Tissue RNA - cervix [nTPM]":"9.0","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"8.3","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"5.3","Tissue RNA - epididymis [nTPM]":"11.1","Tissue RNA - esophagus [nTPM]":"6.8","Tissue RNA - fallopian tube [nTPM]":"8.8","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"10.3","Tissue RNA - hippocampal formation [nTPM]":"10.0","Tissue RNA - hypothalamus [nTPM]":"11.1","Tissue RNA - kidney [nTPM]":"9.3","Tissue RNA - liver [nTPM]":"12.9","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"10.7","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"16.4","Tissue RNA - parathyroid gland [nTPM]":"12.1","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"5.7","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"8.5","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"14.7","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"6.8","Tissue RNA - stomach 1 [nTPM]":"7.2","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"9.9","Tissue RNA - thymus [nTPM]":"9.6","Tissue RNA - thyroid gland [nTPM]":"8.3","Tissue RNA - tongue [nTPM]":"18.0","Tissue RNA - tonsil [nTPM]":"9.2","Tissue RNA - urinary bladder [nTPM]":"5.8","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"12.2","Cell RNA - A549 [nTPM]":"11.9","Cell RNA - AF22 [nTPM]":"7.9","Cell RNA - AN3-CA [nTPM]":"14.5","Cell RNA - ASC diff [nTPM]":"22.5","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"8.2","Cell RNA - BJ [nTPM]":"6.4","Cell RNA - BJ hTERT+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.8","Cell RNA - CACO-2 [nTPM]":"9.3","Cell RNA - CAPAN-2 [nTPM]":"11.0","Cell RNA - Daudi [nTPM]":"13.9","Cell RNA - EFO-21 [nTPM]":"9.5","Cell RNA - fHDF\/TERT166 [nTPM]":"11.9","Cell RNA - GAMG [nTPM]":"8.6","Cell RNA - HaCaT [nTPM]":"6.7","Cell RNA - HAP1 [nTPM]":"18.1","Cell RNA - HBEC3-KT [nTPM]":"18.5","Cell RNA - HBF TERT88 [nTPM]":"12.3","Cell RNA - HDLM-2 [nTPM]":"10.0","Cell RNA - HEK 293 [nTPM]":"12.9","Cell RNA - HEL [nTPM]":"16.6","Cell RNA - HeLa [nTPM]":"10.0","Cell RNA - Hep G2 [nTPM]":"18.2","Cell RNA - HHSteC [nTPM]":"20.2","Cell RNA - HL-60 [nTPM]":"20.7","Cell RNA - HMC-1 [nTPM]":"21.9","Cell RNA - HSkMC [nTPM]":"14.3","Cell RNA - hTCEpi [nTPM]":"19.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.8","Cell RNA - hTERT-HME1 [nTPM]":"15.0","Cell RNA - hTERT-RPE1 [nTPM]":"11.5","Cell RNA - HUVEC TERT2 [nTPM]":"16.8","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"9.5","Cell RNA - Karpas-707 [nTPM]":"13.6","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"2.4","Cell RNA - MOLT-4 [nTPM]":"19.3","Cell RNA - NB-4 [nTPM]":"14.8","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"37.2","Cell RNA - PC-3 [nTPM]":"33.4","Cell RNA - REH [nTPM]":"7.1","Cell RNA - RH-30 [nTPM]":"5.0","Cell RNA - RPMI-8226 [nTPM]":"34.5","Cell RNA - RPTEC TERT1 [nTPM]":"19.7","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"6.0","Cell RNA - SH-SY5Y [nTPM]":"14.1","Cell RNA - SiHa [nTPM]":"7.3","Cell RNA - SK-BR-3 [nTPM]":"11.1","Cell RNA - SK-MEL-30 [nTPM]":"12.5","Cell RNA - SuSa [nTPM]":"8.2","Cell RNA - T-47d [nTPM]":"17.5","Cell RNA - THP-1 [nTPM]":"10.4","Cell RNA - TIME [nTPM]":"6.0","Cell RNA - U-138 MG [nTPM]":"7.2","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"13.8","Cell RNA - U-251 MG [nTPM]":"11.7","Cell RNA - U-266\/70 [nTPM]":"16.8","Cell RNA - U-266\/84 [nTPM]":"22.0","Cell RNA - U-698 [nTPM]":"11.8","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"25.5","Cell RNA - WM-115 [nTPM]":"7.3","Blood RNA - basophil [nTPM]":"40.6","Blood RNA - classical monocyte [nTPM]":"17.4","Blood RNA - eosinophil [nTPM]":"46.7","Blood RNA - gdT-cell [nTPM]":"72.7","Blood RNA - intermediate monocyte [nTPM]":"18.1","Blood RNA - MAIT T-cell [nTPM]":"63.4","Blood RNA - memory B-cell [nTPM]":"23.2","Blood RNA - memory CD4 T-cell [nTPM]":"36.4","Blood RNA - memory CD8 T-cell [nTPM]":"62.7","Blood RNA - myeloid DC [nTPM]":"20.6","Blood RNA - naive B-cell [nTPM]":"21.1","Blood RNA - naive CD4 T-cell [nTPM]":"30.8","Blood RNA - naive CD8 T-cell [nTPM]":"48.5","Blood RNA - neutrophil [nTPM]":"22.9","Blood RNA - NK-cell [nTPM]":"64.1","Blood RNA - non-classical monocyte [nTPM]":"20.8","Blood RNA - plasmacytoid DC [nTPM]":"16.6","Blood RNA - T-reg [nTPM]":"49.8","Blood RNA - total PBMC [nTPM]":"50.7","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"10.0","Brain RNA - cerebral cortex [nTPM]":"11.0","Brain RNA - hippocampal formation [nTPM]":"10.0","Brain RNA - hypothalamus [nTPM]":"11.1","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"10.7","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"9.9","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"13.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.9","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"19.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"18.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"16.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.4","Single Cell Type RNA - dendritic cells [nTPM]":"31.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Ductal cells [nTPM]":"15.9","Single Cell Type RNA - Early spermatids [nTPM]":"94.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.4","Single Cell Type RNA - Endothelial cells [nTPM]":"11.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.9","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.5","Single Cell Type RNA - Fibroblasts [nTPM]":"12.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.1","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"14.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.7","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.9","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"13.2","Single Cell Type RNA - Langerhans cells [nTPM]":"10.3","Single Cell Type RNA - Late spermatids [nTPM]":"66.6","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"7.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"15.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.0","Single Cell Type RNA - NK-cells [nTPM]":"68.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.2","Single Cell Type RNA - Paneth cells [nTPM]":"12.8","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"19.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.1","Single Cell Type RNA - Spermatocytes [nTPM]":"16.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"29.3","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.8","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"NPRL3","Gene synonym":["C16orf35","CGTHBA","HS-40","MARE","NPR3","RMD11"],"Ensembl":"ENSG00000103148","Gene description":"NPR3 like, GATOR1 complex subunit","Uniprot":["Q12980"],"Chromosome":"16","Position":"84271-138677","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"134.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011741"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA011741":"AB_1845577"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.6","Tissue RNA - adrenal gland [nTPM]":"10.4","Tissue RNA - amygdala [nTPM]":"17.5","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"18.2","Tissue RNA - bone marrow [nTPM]":"19.1","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"16.7","Tissue RNA - cerebral cortex [nTPM]":"22.2","Tissue RNA - cervix [nTPM]":"10.1","Tissue RNA - choroid plexus [nTPM]":"15.7","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"12.1","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"8.9","Tissue RNA - hippocampal formation [nTPM]":"17.7","Tissue RNA - hypothalamus [nTPM]":"18.0","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"7.8","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"17.1","Tissue RNA - midbrain [nTPM]":"18.1","Tissue RNA - ovary [nTPM]":"12.9","Tissue RNA - pancreas [nTPM]":"10.9","Tissue RNA - parathyroid gland [nTPM]":"12.7","Tissue RNA - pituitary gland [nTPM]":"11.7","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"16.9","Tissue RNA - prostate [nTPM]":"8.8","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"7.1","Tissue RNA - salivary gland [nTPM]":"11.0","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"15.5","Tissue RNA - skin 1 [nTPM]":"9.9","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"7.2","Tissue RNA - spinal cord [nTPM]":"15.5","Tissue RNA - spleen [nTPM]":"8.3","Tissue RNA - stomach 1 [nTPM]":"6.8","Tissue RNA - testis [nTPM]":"9.4","Tissue RNA - thalamus [nTPM]":"18.2","Tissue RNA - thymus [nTPM]":"7.0","Tissue RNA - thyroid gland [nTPM]":"11.0","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"8.2","Tissue RNA - white matter [nTPM]":"18.2","Cell RNA - A-431 [nTPM]":"14.5","Cell RNA - A549 [nTPM]":"29.0","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"32.2","Cell RNA - ASC diff [nTPM]":"33.7","Cell RNA - ASC TERT1 [nTPM]":"16.9","Cell RNA - BEWO [nTPM]":"19.8","Cell RNA - BJ [nTPM]":"17.2","Cell RNA - BJ hTERT+ [nTPM]":"16.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.6","Cell RNA - CACO-2 [nTPM]":"46.6","Cell RNA - CAPAN-2 [nTPM]":"25.6","Cell RNA - Daudi [nTPM]":"26.5","Cell RNA - EFO-21 [nTPM]":"22.5","Cell RNA - fHDF\/TERT166 [nTPM]":"25.5","Cell RNA - GAMG [nTPM]":"13.8","Cell RNA - HaCaT [nTPM]":"17.0","Cell RNA - HAP1 [nTPM]":"20.5","Cell RNA - HBEC3-KT [nTPM]":"29.7","Cell RNA - HBF TERT88 [nTPM]":"12.3","Cell RNA - HDLM-2 [nTPM]":"29.2","Cell RNA - HEK 293 [nTPM]":"16.0","Cell RNA - HEL [nTPM]":"38.8","Cell RNA - HeLa [nTPM]":"17.3","Cell RNA - Hep G2 [nTPM]":"34.2","Cell RNA - HHSteC [nTPM]":"31.1","Cell RNA - HL-60 [nTPM]":"15.9","Cell RNA - HMC-1 [nTPM]":"25.6","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"22.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.4","Cell RNA - hTERT-HME1 [nTPM]":"24.9","Cell RNA - hTERT-RPE1 [nTPM]":"16.0","Cell RNA - HUVEC TERT2 [nTPM]":"20.3","Cell RNA - JURKAT [nTPM]":"21.1","Cell RNA - K-562 [nTPM]":"38.6","Cell RNA - Karpas-707 [nTPM]":"24.6","Cell RNA - LHCN-M2 [nTPM]":"19.1","Cell RNA - MCF7 [nTPM]":"51.2","Cell RNA - MOLT-4 [nTPM]":"17.6","Cell RNA - NB-4 [nTPM]":"12.3","Cell RNA - NTERA-2 [nTPM]":"11.9","Cell RNA - OE19 [nTPM]":"10.0","Cell RNA - PC-3 [nTPM]":"20.8","Cell RNA - REH [nTPM]":"30.1","Cell RNA - RH-30 [nTPM]":"10.8","Cell RNA - RPMI-8226 [nTPM]":"37.9","Cell RNA - RPTEC TERT1 [nTPM]":"21.6","Cell RNA - RT4 [nTPM]":"12.2","Cell RNA - SCLC-21H [nTPM]":"26.9","Cell RNA - SH-SY5Y [nTPM]":"17.1","Cell RNA - SiHa [nTPM]":"22.8","Cell RNA - SK-BR-3 [nTPM]":"30.1","Cell RNA - SK-MEL-30 [nTPM]":"14.3","Cell RNA - SuSa [nTPM]":"6.5","Cell RNA - T-47d [nTPM]":"22.2","Cell RNA - THP-1 [nTPM]":"11.1","Cell RNA - TIME [nTPM]":"19.2","Cell RNA - U-138 MG [nTPM]":"32.9","Cell RNA - U-2 OS [nTPM]":"18.2","Cell RNA - U-2197 [nTPM]":"20.0","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"25.9","Cell RNA - U-266\/84 [nTPM]":"14.7","Cell RNA - U-698 [nTPM]":"37.7","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"19.2","Cell RNA - WM-115 [nTPM]":"18.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"2.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.9","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"3.1","Blood RNA - plasmacytoid DC [nTPM]":"2.6","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"17.5","Brain RNA - basal ganglia [nTPM]":"18.2","Brain RNA - cerebellum [nTPM]":"16.7","Brain RNA - cerebral cortex [nTPM]":"22.2","Brain RNA - hippocampal formation [nTPM]":"17.7","Brain RNA - hypothalamus [nTPM]":"18.0","Brain RNA - medulla oblongata [nTPM]":"17.1","Brain RNA - midbrain [nTPM]":"18.1","Brain RNA - pons [nTPM]":"16.9","Brain RNA - spinal cord [nTPM]":"15.5","Brain RNA - thalamus [nTPM]":"18.2","Brain RNA - white matter [nTPM]":"18.2","Single Cell Type RNA - Adipocytes [nTPM]":"10.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.7","Single Cell Type RNA - Astrocytes [nTPM]":"30.0","Single Cell Type RNA - B-cells [nTPM]":"22.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"58.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.6","Single Cell Type RNA - dendritic cells [nTPM]":"20.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"16.4","Single Cell Type RNA - Early spermatids [nTPM]":"31.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.1","Single Cell Type RNA - Endothelial cells [nTPM]":"13.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"134.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.2","Single Cell Type RNA - Fibroblasts [nTPM]":"17.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.4","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"49.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"10.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.7","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.7","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.4","Single Cell Type RNA - Late spermatids [nTPM]":"73.8","Single Cell Type RNA - Leydig cells [nTPM]":"22.7","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"16.4","Single Cell Type RNA - Muller glia cells [nTPM]":"29.5","Single Cell Type RNA - NK-cells [nTPM]":"79.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"40.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.6","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"14.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"57.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.9","Single Cell Type RNA - Spermatocytes [nTPM]":"62.2","Single Cell Type RNA - Spermatogonia [nTPM]":"43.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.3","Single Cell Type RNA - T-cells [nTPM]":"18.8","Single Cell Type RNA - Theca cells [nTPM]":"28.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.4","Single Cell Type RNA - Urothelial cells [nTPM]":"10.4"},{"Gene":"NR2E3","Gene synonym":["PNR","rd7","RP37"],"Ensembl":"ENSG00000278570","Gene description":"Nuclear receptor subfamily 2 group E member 3","Uniprot":["Q9Y5X4"],"Chromosome":"15","Position":"71792638-71818259","Protein class":["Disease related genes","Human disease related genes","Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Sensory transduction","Transcription","Transcription regulation","Vision"],"Molecular function":["DNA-binding","Receptor","Repressor"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"131","RNA tissue specific nTPM":{"retina":"131.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"1357.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"131.4","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"33.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"45.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1357.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"4.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"NR2F1","Gene synonym":["COUP-TFI","COUPTF1","EAR-3","ERBAL3","SVP44","TCFCOUP1","TFCOUP1"],"Ensembl":"ENSG00000175745","Gene description":"Nuclear receptor subfamily 2 group F member 1","Uniprot":["P10589"],"Chromosome":"5","Position":"93583222-93594611","Protein class":["Disease related genes","Human disease related genes","Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Receptor","Repressor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"294.1","Hepatic stellate cells":"171.4","Leydig cells":"93.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"232.4","AN3-CA":"92.9","HHSteC":"174.1","hTERT-RPE1":"155.1","PC-3":"194.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019281","HPA058974"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB019281":null,"HPA058974":"AB_2732629"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.47e-4"},"Tissue RNA - adipose tissue [nTPM]":"42.2","Tissue RNA - adrenal gland [nTPM]":"40.3","Tissue RNA - amygdala [nTPM]":"41.8","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"39.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"20.4","Tissue RNA - cerebellum [nTPM]":"32.9","Tissue RNA - cerebral cortex [nTPM]":"50.7","Tissue RNA - cervix [nTPM]":"65.1","Tissue RNA - choroid plexus [nTPM]":"12.8","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"29.4","Tissue RNA - epididymis [nTPM]":"25.2","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"77.9","Tissue RNA - gallbladder [nTPM]":"34.3","Tissue RNA - heart muscle [nTPM]":"16.1","Tissue RNA - hippocampal formation [nTPM]":"44.7","Tissue RNA - hypothalamus [nTPM]":"25.6","Tissue RNA - kidney [nTPM]":"32.8","Tissue RNA - liver [nTPM]":"13.0","Tissue RNA - lung [nTPM]":"44.4","Tissue RNA - lymph node [nTPM]":"8.3","Tissue RNA - medulla oblongata [nTPM]":"31.6","Tissue RNA - midbrain [nTPM]":"41.1","Tissue RNA - ovary [nTPM]":"62.7","Tissue RNA - pancreas [nTPM]":"7.6","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"21.6","Tissue RNA - placenta [nTPM]":"52.6","Tissue RNA - pons [nTPM]":"23.8","Tissue RNA - prostate [nTPM]":"44.9","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"6.9","Tissue RNA - seminal vesicle [nTPM]":"40.3","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"7.4","Tissue RNA - smooth muscle [nTPM]":"11.8","Tissue RNA - spinal cord [nTPM]":"31.5","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"28.8","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"42.4","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"16.9","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"49.1","Tissue RNA - vagina [nTPM]":"40.6","Tissue RNA - white matter [nTPM]":"30.8","Cell RNA - A-431 [nTPM]":"20.1","Cell RNA - A549 [nTPM]":"9.5","Cell RNA - AF22 [nTPM]":"232.4","Cell RNA - AN3-CA [nTPM]":"92.9","Cell RNA - ASC diff [nTPM]":"48.3","Cell RNA - ASC TERT1 [nTPM]":"14.8","Cell RNA - BEWO [nTPM]":"11.0","Cell RNA - BJ [nTPM]":"11.6","Cell RNA - BJ hTERT+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.1","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"3.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"4.7","Cell RNA - GAMG [nTPM]":"2.8","Cell RNA - HaCaT [nTPM]":"5.0","Cell RNA - HAP1 [nTPM]":"5.7","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"3.0","Cell RNA - HDLM-2 [nTPM]":"24.7","Cell RNA - HEK 293 [nTPM]":"45.2","Cell RNA - HEL [nTPM]":"9.2","Cell RNA - HeLa [nTPM]":"61.9","Cell RNA - Hep G2 [nTPM]":"15.1","Cell RNA - HHSteC [nTPM]":"174.1","Cell RNA - HL-60 [nTPM]":"1.9","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"69.7","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"155.1","Cell RNA - HUVEC TERT2 [nTPM]":"26.3","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"21.4","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.7","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"194.2","Cell RNA - REH [nTPM]":"2.8","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"23.9","Cell RNA - SH-SY5Y [nTPM]":"48.4","Cell RNA - SiHa [nTPM]":"5.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"4.0","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"3.7","Cell RNA - TIME [nTPM]":"26.7","Cell RNA - U-138 MG [nTPM]":"39.3","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"20.6","Cell RNA - U-251 MG [nTPM]":"29.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"64.2","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"17.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"41.8","Brain RNA - basal ganglia [nTPM]":"39.0","Brain RNA - cerebellum [nTPM]":"32.9","Brain RNA - cerebral cortex [nTPM]":"50.7","Brain RNA - hippocampal formation [nTPM]":"44.7","Brain RNA - hypothalamus [nTPM]":"25.6","Brain RNA - medulla oblongata [nTPM]":"31.6","Brain RNA - midbrain [nTPM]":"41.1","Brain RNA - pons [nTPM]":"23.8","Brain RNA - spinal cord [nTPM]":"31.5","Brain RNA - thalamus [nTPM]":"42.4","Brain RNA - white matter [nTPM]":"30.8","Single Cell Type RNA - Adipocytes [nTPM]":"16.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"68.2","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"32.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"294.1","Single Cell Type RNA - Endothelial cells [nTPM]":"70.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"69.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"29.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"171.4","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"15.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"93.5","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"59.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"69.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"11.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"NR4A2","Gene synonym":["HZF-3","NOT","NURR1","RNR1","TINUR"],"Ensembl":"ENSG00000153234","Gene description":"Nuclear receptor subfamily 4 group A member 2","Uniprot":["P43354"],"Chromosome":"2","Position":"156324437-156342348","Protein class":["Cancer-related genes","Human disease related genes","Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"129.3","bone marrow":"130.8","ovary":"129.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"511.7","dendritic cells":"410.4","Langerhans cells":"782.3","Macrophages":"577.5","T-cells":"465.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"6.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"16.0","HMC-1":"10.9","SK-MEL-30":"8.1","U-266\/70":"14.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000543","CAB010481"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"CAB010481":"AB_2298676","HPA000543":"AB_1854631"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"40.0","Tissue RNA - adrenal gland [nTPM]":"129.3","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"24.5","Tissue RNA - basal ganglia [nTPM]":"44.1","Tissue RNA - bone marrow [nTPM]":"130.8","Tissue RNA - breast [nTPM]":"15.6","Tissue RNA - cerebellum [nTPM]":"36.2","Tissue RNA - cerebral cortex [nTPM]":"8.8","Tissue RNA - cervix [nTPM]":"18.3","Tissue RNA - choroid plexus [nTPM]":"5.9","Tissue RNA - colon [nTPM]":"9.5","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"15.0","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"11.4","Tissue RNA - fallopian tube [nTPM]":"28.2","Tissue RNA - gallbladder [nTPM]":"32.7","Tissue RNA - heart muscle [nTPM]":"36.6","Tissue RNA - hippocampal formation [nTPM]":"15.1","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"19.2","Tissue RNA - liver [nTPM]":"20.2","Tissue RNA - lung [nTPM]":"18.8","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"129.2","Tissue RNA - pancreas [nTPM]":"9.2","Tissue RNA - parathyroid gland [nTPM]":"8.8","Tissue RNA - pituitary gland [nTPM]":"54.0","Tissue RNA - placenta [nTPM]":"5.2","Tissue RNA - pons [nTPM]":"2.8","Tissue RNA - prostate [nTPM]":"25.6","Tissue RNA - rectum [nTPM]":"18.7","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"19.2","Tissue RNA - seminal vesicle [nTPM]":"15.5","Tissue RNA - skeletal muscle [nTPM]":"11.6","Tissue RNA - skin 1 [nTPM]":"12.8","Tissue RNA - small intestine [nTPM]":"7.8","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"19.9","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"15.2","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"50.9","Tissue RNA - vagina [nTPM]":"14.0","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"0.9","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"1.8","Cell RNA - ASC diff [nTPM]":"3.2","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"5.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"3.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"1.6","Cell RNA - HAP1 [nTPM]":"2.6","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"16.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"10.9","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"1.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.6","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"1.5","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"3.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.6","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"4.1","Cell RNA - SK-MEL-30 [nTPM]":"8.1","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"2.9","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"14.2","Cell RNA - U-266\/84 [nTPM]":"1.8","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.3","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"7.0","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"6.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"44.1","Brain RNA - cerebellum [nTPM]":"36.2","Brain RNA - cerebral cortex [nTPM]":"8.8","Brain RNA - hippocampal formation [nTPM]":"15.1","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"2.8","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"70.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"124.7","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"511.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"218.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"87.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"298.7","Single Cell Type RNA - Bipolar cells [nTPM]":"11.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"120.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"160.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"58.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.7","Single Cell Type RNA - dendritic cells [nTPM]":"410.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"35.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"13.1","Single Cell Type RNA - Early spermatids [nTPM]":"36.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"209.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.9","Single Cell Type RNA - Endothelial cells [nTPM]":"111.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"206.4","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.5","Single Cell Type RNA - Fibroblasts [nTPM]":"164.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"103.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"349.7","Single Cell Type RNA - granulocytes [nTPM]":"349.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"45.0","Single Cell Type RNA - Hepatocytes [nTPM]":"6.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"125.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"95.4","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"161.1","Single Cell Type RNA - Langerhans cells [nTPM]":"782.3","Single Cell Type RNA - Late spermatids [nTPM]":"37.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"577.5","Single Cell Type RNA - Melanocytes [nTPM]":"241.9","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"7.9","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"41.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"203.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"49.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"54.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"63.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"169.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"230.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"213.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - T-cells [nTPM]":"465.1","Single Cell Type RNA - Theca cells [nTPM]":"34.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"57.5","Single Cell Type RNA - Urothelial cells [nTPM]":"29.5"},{"Gene":"NRL","Gene synonym":["D14S46E","NRL-MAF","RP27"],"Ensembl":"ENSG00000129535","Gene description":"Neural retina leucine zipper","Uniprot":["P54845"],"Chromosome":"14","Position":"24078662-24115010","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Sensory transduction","Transcription","Transcription regulation","Vision"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"75","RNA tissue specific nTPM":{"retina":"317.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"3720.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SuSa":"4.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026066","HPA064599"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB026066":null,"HPA064599":"AB_2685295"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"3.1","Tissue RNA - liver [nTPM]":"3.6","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"1.9","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"317.3","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"1.6","Cell RNA - AN3-CA [nTPM]":"1.6","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"1.2","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"2.2","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"2.2","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"1.2","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"1.8","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"1.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"3.6","Cell RNA - U-266\/84 [nTPM]":"1.9","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"1.1","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"6.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"434.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"431.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"24.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"3.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.0","Single Cell Type RNA - Horizontal cells [nTPM]":"250.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"636.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"5.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3720.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"9.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"NT5C2","Gene synonym":["cN-II","GMP","NT5B","PNT5","SPG45","SPG65"],"Ensembl":"ENSG00000076685","Gene description":"5'-nucleotidase, cytosolic II","Uniprot":["P49902"],"Chromosome":"10","Position":"103087185-103277605","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Nucleotide metabolism"],"Molecular function":["Allosteric enzyme","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"141.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003751"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003751":"AB_1854664"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.6","Tissue RNA - adrenal gland [nTPM]":"27.0","Tissue RNA - amygdala [nTPM]":"25.0","Tissue RNA - appendix [nTPM]":"19.0","Tissue RNA - basal ganglia [nTPM]":"27.2","Tissue RNA - bone marrow [nTPM]":"29.7","Tissue RNA - breast [nTPM]":"23.0","Tissue RNA - cerebellum [nTPM]":"27.3","Tissue RNA - cerebral cortex [nTPM]":"28.5","Tissue RNA - cervix [nTPM]":"37.6","Tissue RNA - choroid plexus [nTPM]":"36.8","Tissue RNA - colon [nTPM]":"27.3","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"18.8","Tissue RNA - epididymis [nTPM]":"17.3","Tissue RNA - esophagus [nTPM]":"67.1","Tissue RNA - fallopian tube [nTPM]":"26.5","Tissue RNA - gallbladder [nTPM]":"16.4","Tissue RNA - heart muscle [nTPM]":"28.5","Tissue RNA - hippocampal formation [nTPM]":"25.2","Tissue RNA - hypothalamus [nTPM]":"28.8","Tissue RNA - kidney [nTPM]":"32.5","Tissue RNA - liver [nTPM]":"27.8","Tissue RNA - lung [nTPM]":"30.8","Tissue RNA - lymph node [nTPM]":"18.3","Tissue RNA - medulla oblongata [nTPM]":"26.9","Tissue RNA - midbrain [nTPM]":"29.5","Tissue RNA - ovary [nTPM]":"32.4","Tissue RNA - pancreas [nTPM]":"22.0","Tissue RNA - parathyroid gland [nTPM]":"21.7","Tissue RNA - pituitary gland [nTPM]":"34.0","Tissue RNA - placenta [nTPM]":"17.9","Tissue RNA - pons [nTPM]":"27.2","Tissue RNA - prostate [nTPM]":"32.4","Tissue RNA - rectum [nTPM]":"16.7","Tissue RNA - retina [nTPM]":"47.3","Tissue RNA - salivary gland [nTPM]":"46.4","Tissue RNA - seminal vesicle [nTPM]":"18.4","Tissue RNA - skeletal muscle [nTPM]":"51.6","Tissue RNA - skin 1 [nTPM]":"19.9","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"13.4","Tissue RNA - spinal cord [nTPM]":"26.4","Tissue RNA - spleen [nTPM]":"32.8","Tissue RNA - stomach 1 [nTPM]":"22.3","Tissue RNA - testis [nTPM]":"30.8","Tissue RNA - thalamus [nTPM]":"27.2","Tissue RNA - thymus [nTPM]":"28.6","Tissue RNA - thyroid gland [nTPM]":"55.4","Tissue RNA - tongue [nTPM]":"18.1","Tissue RNA - tonsil [nTPM]":"24.5","Tissue RNA - urinary bladder [nTPM]":"33.3","Tissue RNA - vagina [nTPM]":"42.7","Tissue RNA - white matter [nTPM]":"28.6","Cell RNA - A-431 [nTPM]":"148.4","Cell RNA - A549 [nTPM]":"52.5","Cell RNA - AF22 [nTPM]":"32.6","Cell RNA - AN3-CA [nTPM]":"67.5","Cell RNA - ASC diff [nTPM]":"27.2","Cell RNA - ASC TERT1 [nTPM]":"33.2","Cell RNA - BEWO [nTPM]":"18.2","Cell RNA - BJ [nTPM]":"66.0","Cell RNA - BJ hTERT+ [nTPM]":"64.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.4","Cell RNA - CACO-2 [nTPM]":"34.6","Cell RNA - CAPAN-2 [nTPM]":"91.7","Cell RNA - Daudi [nTPM]":"49.2","Cell RNA - EFO-21 [nTPM]":"47.7","Cell RNA - fHDF\/TERT166 [nTPM]":"45.6","Cell RNA - GAMG [nTPM]":"27.6","Cell RNA - HaCaT [nTPM]":"62.8","Cell RNA - HAP1 [nTPM]":"23.4","Cell RNA - HBEC3-KT [nTPM]":"33.8","Cell RNA - HBF TERT88 [nTPM]":"38.3","Cell RNA - HDLM-2 [nTPM]":"40.3","Cell RNA - HEK 293 [nTPM]":"21.6","Cell RNA - HEL [nTPM]":"38.7","Cell RNA - HeLa [nTPM]":"21.1","Cell RNA - Hep G2 [nTPM]":"39.6","Cell RNA - HHSteC [nTPM]":"48.5","Cell RNA - HL-60 [nTPM]":"64.2","Cell RNA - HMC-1 [nTPM]":"21.0","Cell RNA - HSkMC [nTPM]":"50.4","Cell RNA - hTCEpi [nTPM]":"34.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.0","Cell RNA - hTERT-HME1 [nTPM]":"24.8","Cell RNA - hTERT-RPE1 [nTPM]":"57.5","Cell RNA - HUVEC TERT2 [nTPM]":"25.6","Cell RNA - JURKAT [nTPM]":"19.4","Cell RNA - K-562 [nTPM]":"29.4","Cell RNA - Karpas-707 [nTPM]":"36.4","Cell RNA - LHCN-M2 [nTPM]":"54.5","Cell RNA - MCF7 [nTPM]":"73.8","Cell RNA - MOLT-4 [nTPM]":"53.7","Cell RNA - NB-4 [nTPM]":"64.6","Cell RNA - NTERA-2 [nTPM]":"34.6","Cell RNA - OE19 [nTPM]":"43.2","Cell RNA - PC-3 [nTPM]":"68.6","Cell RNA - REH [nTPM]":"102.6","Cell RNA - RH-30 [nTPM]":"30.0","Cell RNA - RPMI-8226 [nTPM]":"19.6","Cell RNA - RPTEC TERT1 [nTPM]":"43.3","Cell RNA - RT4 [nTPM]":"72.5","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"24.9","Cell RNA - SiHa [nTPM]":"35.8","Cell RNA - SK-BR-3 [nTPM]":"25.9","Cell RNA - SK-MEL-30 [nTPM]":"50.3","Cell RNA - SuSa [nTPM]":"33.7","Cell RNA - T-47d [nTPM]":"39.2","Cell RNA - THP-1 [nTPM]":"38.1","Cell RNA - TIME [nTPM]":"30.5","Cell RNA - U-138 MG [nTPM]":"20.5","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"39.7","Cell RNA - U-251 MG [nTPM]":"51.7","Cell RNA - U-266\/70 [nTPM]":"32.9","Cell RNA - U-266\/84 [nTPM]":"71.6","Cell RNA - U-698 [nTPM]":"85.5","Cell RNA - U-87 MG [nTPM]":"23.9","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"7.8","Blood RNA - basophil [nTPM]":"29.5","Blood RNA - classical monocyte [nTPM]":"16.5","Blood RNA - eosinophil [nTPM]":"31.3","Blood RNA - gdT-cell [nTPM]":"10.0","Blood RNA - intermediate monocyte [nTPM]":"18.8","Blood RNA - MAIT T-cell [nTPM]":"10.3","Blood RNA - memory B-cell [nTPM]":"8.9","Blood RNA - memory CD4 T-cell [nTPM]":"8.4","Blood RNA - memory CD8 T-cell [nTPM]":"8.7","Blood RNA - myeloid DC [nTPM]":"14.7","Blood RNA - naive B-cell [nTPM]":"5.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.7","Blood RNA - naive CD8 T-cell [nTPM]":"8.0","Blood RNA - neutrophil [nTPM]":"27.4","Blood RNA - NK-cell [nTPM]":"14.4","Blood RNA - non-classical monocyte [nTPM]":"23.0","Blood RNA - plasmacytoid DC [nTPM]":"9.6","Blood RNA - T-reg [nTPM]":"9.3","Blood RNA - total PBMC [nTPM]":"10.5","Brain RNA - amygdala [nTPM]":"25.0","Brain RNA - basal ganglia [nTPM]":"27.2","Brain RNA - cerebellum [nTPM]":"27.3","Brain RNA - cerebral cortex [nTPM]":"28.5","Brain RNA - hippocampal formation [nTPM]":"25.2","Brain RNA - hypothalamus [nTPM]":"28.8","Brain RNA - medulla oblongata [nTPM]":"26.9","Brain RNA - midbrain [nTPM]":"29.5","Brain RNA - pons [nTPM]":"27.2","Brain RNA - spinal cord [nTPM]":"26.4","Brain RNA - thalamus [nTPM]":"27.2","Brain RNA - white matter [nTPM]":"28.6","Single Cell Type RNA - Adipocytes [nTPM]":"16.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.9","Single Cell Type RNA - Astrocytes [nTPM]":"141.7","Single Cell Type RNA - B-cells [nTPM]":"17.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"24.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"60.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"23.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"48.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"28.5","Single Cell Type RNA - Early spermatids [nTPM]":"103.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.1","Single Cell Type RNA - Endothelial cells [nTPM]":"19.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"79.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.7","Single Cell Type RNA - Fibroblasts [nTPM]":"17.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.2","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"18.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"17.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.9","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"83.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.6","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"29.8","Single Cell Type RNA - Langerhans cells [nTPM]":"14.2","Single Cell Type RNA - Late spermatids [nTPM]":"61.9","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"27.1","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"78.7","Single Cell Type RNA - monocytes [nTPM]":"25.9","Single Cell Type RNA - Muller glia cells [nTPM]":"85.5","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"70.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"107.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"57.9","Single Cell Type RNA - Paneth cells [nTPM]":"23.1","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"21.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"44.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.7","Single Cell Type RNA - Spermatocytes [nTPM]":"25.3","Single Cell Type RNA - Spermatogonia [nTPM]":"20.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.0","Single Cell Type RNA - T-cells [nTPM]":"16.6","Single Cell Type RNA - Theca cells [nTPM]":"15.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.0","Single Cell Type RNA - Urothelial cells [nTPM]":"80.5"},{"Gene":"NTF4","Gene synonym":["GLC1O","NT-4\/5","NTF5"],"Ensembl":"ENSG00000225950","Gene description":"Neurotrophin 4","Uniprot":["P34130"],"Chromosome":"19","Position":"49061066-49065054","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes","Glaucoma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"20.1","skeletal muscle":"17.1","skin 1":"31.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"35.6","Basal respiratory cells":"24.0","Basal squamous epithelial cells":"15.4","Breast myoepithelial cells":"24.3","Club cells":"9.5","Cytotrophoblasts":"13.6","Urothelial cells":"11.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"13.8","HaCaT":"31.1","HBEC3-KT":"11.7","hTCEpi":"50.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049376"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA049376":"AB_2680735"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"5.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"4.3","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"10.8","Tissue RNA - fallopian tube [nTPM]":"2.5","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"3.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"20.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"8.2","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"17.1","Tissue RNA - skin 1 [nTPM]":"31.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"9.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.4","Cell RNA - CAPAN-2 [nTPM]":"13.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"31.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"11.7","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"50.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.6","Cell RNA - hTERT-RPE1 [nTPM]":"3.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"8.8","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"4.3","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"1.8","Cell RNA - U-2 OS [nTPM]":"3.5","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"9.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"9.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"11.9"},{"Gene":"NTN1","Gene synonym":["NTN1L"],"Ensembl":"ENSG00000065320","Gene description":"Netrin 1","Uniprot":["O95631"],"Chromosome":"17","Position":"9021510-9244000","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"37.1","heart muscle":"59.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"137.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"27.5","T-47d":"16.6","U-2 OS":"14.4","U-251 MG":"22.1","WM-115":"12.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056419"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Actin filaments","Cytosol"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Actin filaments"],"Antibody RRID":{"HPA056419":"AB_2683124"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.4","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"4.5","Tissue RNA - appendix [nTPM]":"3.6","Tissue RNA - basal ganglia [nTPM]":"6.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"10.1","Tissue RNA - cerebral cortex [nTPM]":"4.9","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"14.7","Tissue RNA - duodenum [nTPM]":"6.7","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"18.9","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"59.4","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"6.9","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"12.7","Tissue RNA - midbrain [nTPM]":"37.1","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"14.4","Tissue RNA - prostate [nTPM]":"3.9","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"8.1","Tissue RNA - small intestine [nTPM]":"10.5","Tissue RNA - smooth muscle [nTPM]":"6.0","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"17.5","Tissue RNA - testis [nTPM]":"3.1","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"2.6","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"10.2","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"8.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"4.2","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"27.5","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"5.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"9.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"0.9","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"6.4","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"2.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"5.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"3.4","Cell RNA - RH-30 [nTPM]":"4.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"1.1","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"16.6","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"6.7","Cell RNA - U-2 OS [nTPM]":"14.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"22.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"12.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.5","Brain RNA - basal ganglia [nTPM]":"6.4","Brain RNA - cerebellum [nTPM]":"10.1","Brain RNA - cerebral cortex [nTPM]":"4.9","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"12.7","Brain RNA - midbrain [nTPM]":"37.1","Brain RNA - pons [nTPM]":"14.4","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"8.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"23.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.1","Single Cell Type RNA - Early spermatids [nTPM]":"9.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"12.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.4","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"137.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.5"},{"Gene":"NTRK1","Gene synonym":["MTC","TRK","TRKA"],"Ensembl":"ENSG00000198400","Gene description":"Neurotrophic receptor tyrosine kinase 1","Uniprot":["P04629"],"Chromosome":"1","Position":"156815640-156881850","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"7.0","brain":"21.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Bipolar cells":"22.8","granulocytes":"55.9","Horizontal cells":"57.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"7.6","medulla oblongata":"19.8","pons":"21.7"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"116","RNA blood cell specific nTPM":{"basophil":"94.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"768","RNA blood lineage specific nTPM":{"granulocytes":"94.5"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HMC-1":"82.1"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"8.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"4.1"},"Antibody":["CAB004606","HPA035799","HPA076570"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"79000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004606":"AB_628397","HPA035799":"AB_2674788","HPA076570":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"3.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"19.8","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"21.7","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"11.9","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"14.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"82.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"4.4","Cell RNA - Karpas-707 [nTPM]":"1.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.4","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"2.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"18.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.5","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"94.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"19.8","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"21.7","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"55.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NTRK2","Gene synonym":["TRKB"],"Ensembl":"ENSG00000148053","Gene description":"Neurotrophic receptor tyrosine kinase 2","Uniprot":["Q16620"],"Chromosome":"9","Position":"84668551-85027054","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","FDA approved drug targets","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"230.0","thyroid gland":"116.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1144.3","Excitatory neurons":"750.1","Inhibitory neurons":"877.7","Oligodendrocyte precursor cells":"557.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"31.6","head and neck cancer":"8.0","lung cancer":"9.8","thyroid cancer":"26.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"8.7","HaCaT":"3.0","RPTEC TERT1":"9.7","SH-SY5Y":"11.2","SuSa":"4.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007637","CAB010346","HPA074873"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010346":"AB_2155274","HPA007637":"AB_1080385","HPA074873":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Tissue RNA - adipose tissue [nTPM]":"40.5","Tissue RNA - adrenal gland [nTPM]":"2.7","Tissue RNA - amygdala [nTPM]":"201.9","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"177.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"62.2","Tissue RNA - cerebellum [nTPM]":"133.3","Tissue RNA - cerebral cortex [nTPM]":"190.6","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"69.8","Tissue RNA - colon [nTPM]":"5.9","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"33.3","Tissue RNA - heart muscle [nTPM]":"15.2","Tissue RNA - hippocampal formation [nTPM]":"173.3","Tissue RNA - hypothalamus [nTPM]":"230.0","Tissue RNA - kidney [nTPM]":"20.4","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"10.0","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"119.4","Tissue RNA - midbrain [nTPM]":"218.9","Tissue RNA - ovary [nTPM]":"9.7","Tissue RNA - pancreas [nTPM]":"34.3","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"151.7","Tissue RNA - prostate [nTPM]":"4.7","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"41.2","Tissue RNA - salivary gland [nTPM]":"14.4","Tissue RNA - seminal vesicle [nTPM]":"19.1","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"11.6","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"3.3","Tissue RNA - spinal cord [nTPM]":"116.6","Tissue RNA - spleen [nTPM]":"10.9","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"222.1","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"116.9","Tissue RNA - tongue [nTPM]":"13.8","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"117.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"8.7","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"9.7","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"11.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"201.9","Brain RNA - basal ganglia [nTPM]":"177.8","Brain RNA - cerebellum [nTPM]":"133.3","Brain RNA - cerebral cortex [nTPM]":"190.6","Brain RNA - hippocampal formation [nTPM]":"173.3","Brain RNA - hypothalamus [nTPM]":"230.0","Brain RNA - medulla oblongata [nTPM]":"119.4","Brain RNA - midbrain [nTPM]":"218.9","Brain RNA - pons [nTPM]":"151.7","Brain RNA - spinal cord [nTPM]":"116.6","Brain RNA - thalamus [nTPM]":"222.1","Brain RNA - white matter [nTPM]":"117.7","Single Cell Type RNA - Adipocytes [nTPM]":"17.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1144.3","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"93.9","Single Cell Type RNA - Bipolar cells [nTPM]":"30.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"144.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"116.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"36.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"750.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"76.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"242.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"877.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"14.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"104.1","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"65.6","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"241.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"557.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"109.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"7.0","Single Cell Type RNA - Peritubular cells [nTPM]":"48.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.2","Single Cell Type RNA - Sertoli cells [nTPM]":"124.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"114.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"NUP62","Gene synonym":["DKFZp547L134","FLJ20822","FLJ43869","IBSN","MGC841","p62","SNDI"],"Ensembl":"ENSG00000213024","Gene description":"Nucleoporin 62","Uniprot":["P37198"],"Chromosome":"19","Position":"49906825-49929763","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Host-virus interaction","mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"119.2","Late spermatids":"315.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005435","CAB020724"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"31000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB020724":null,"HPA005435":"AB_1079510"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.50e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.71e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Tissue RNA - adipose tissue [nTPM]":"19.9","Tissue RNA - adrenal gland [nTPM]":"29.4","Tissue RNA - amygdala [nTPM]":"14.2","Tissue RNA - appendix [nTPM]":"37.3","Tissue RNA - basal ganglia [nTPM]":"13.2","Tissue RNA - bone marrow [nTPM]":"27.1","Tissue RNA - breast [nTPM]":"18.9","Tissue RNA - cerebellum [nTPM]":"18.4","Tissue RNA - cerebral cortex [nTPM]":"15.9","Tissue RNA - cervix [nTPM]":"22.5","Tissue RNA - choroid plexus [nTPM]":"14.0","Tissue RNA - colon [nTPM]":"22.5","Tissue RNA - duodenum [nTPM]":"23.7","Tissue RNA - endometrium 1 [nTPM]":"27.6","Tissue RNA - epididymis [nTPM]":"11.0","Tissue RNA - esophagus [nTPM]":"25.0","Tissue RNA - fallopian tube [nTPM]":"24.8","Tissue RNA - gallbladder [nTPM]":"18.4","Tissue RNA - heart muscle [nTPM]":"20.4","Tissue RNA - hippocampal formation [nTPM]":"13.9","Tissue RNA - hypothalamus [nTPM]":"15.7","Tissue RNA - kidney [nTPM]":"18.5","Tissue RNA - liver [nTPM]":"31.7","Tissue RNA - lung [nTPM]":"19.4","Tissue RNA - lymph node [nTPM]":"38.3","Tissue RNA - medulla oblongata [nTPM]":"15.5","Tissue RNA - midbrain [nTPM]":"14.2","Tissue RNA - ovary [nTPM]":"29.8","Tissue RNA - pancreas [nTPM]":"21.0","Tissue RNA - parathyroid gland [nTPM]":"18.0","Tissue RNA - pituitary gland [nTPM]":"22.8","Tissue RNA - placenta [nTPM]":"22.4","Tissue RNA - pons [nTPM]":"15.8","Tissue RNA - prostate [nTPM]":"19.9","Tissue RNA - rectum [nTPM]":"21.1","Tissue RNA - retina [nTPM]":"11.1","Tissue RNA - salivary gland [nTPM]":"21.8","Tissue RNA - seminal vesicle [nTPM]":"17.5","Tissue RNA - skeletal muscle [nTPM]":"33.7","Tissue RNA - skin 1 [nTPM]":"23.4","Tissue RNA - small intestine [nTPM]":"24.3","Tissue RNA - smooth muscle [nTPM]":"27.7","Tissue RNA - spinal cord [nTPM]":"13.6","Tissue RNA - spleen [nTPM]":"29.8","Tissue RNA - stomach 1 [nTPM]":"19.4","Tissue RNA - testis [nTPM]":"50.4","Tissue RNA - thalamus [nTPM]":"14.7","Tissue RNA - thymus [nTPM]":"41.9","Tissue RNA - thyroid gland [nTPM]":"16.3","Tissue RNA - tongue [nTPM]":"24.5","Tissue RNA - tonsil [nTPM]":"37.7","Tissue RNA - urinary bladder [nTPM]":"24.6","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"16.9","Cell RNA - A-431 [nTPM]":"126.7","Cell RNA - A549 [nTPM]":"115.5","Cell RNA - AF22 [nTPM]":"88.8","Cell RNA - AN3-CA [nTPM]":"74.0","Cell RNA - ASC diff [nTPM]":"26.0","Cell RNA - ASC TERT1 [nTPM]":"30.0","Cell RNA - BEWO [nTPM]":"79.7","Cell RNA - BJ [nTPM]":"92.8","Cell RNA - BJ hTERT+ [nTPM]":"65.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"99.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"98.8","Cell RNA - CACO-2 [nTPM]":"79.8","Cell RNA - CAPAN-2 [nTPM]":"71.9","Cell RNA - Daudi [nTPM]":"141.2","Cell RNA - EFO-21 [nTPM]":"51.7","Cell RNA - fHDF\/TERT166 [nTPM]":"60.8","Cell RNA - GAMG [nTPM]":"65.9","Cell RNA - HaCaT [nTPM]":"73.6","Cell RNA - HAP1 [nTPM]":"108.3","Cell RNA - HBEC3-KT [nTPM]":"62.1","Cell RNA - HBF TERT88 [nTPM]":"96.1","Cell RNA - HDLM-2 [nTPM]":"211.6","Cell RNA - HEK 293 [nTPM]":"112.0","Cell RNA - HEL [nTPM]":"109.8","Cell RNA - HeLa [nTPM]":"59.4","Cell RNA - Hep G2 [nTPM]":"72.6","Cell RNA - HHSteC [nTPM]":"30.9","Cell RNA - HL-60 [nTPM]":"108.8","Cell RNA - HMC-1 [nTPM]":"106.8","Cell RNA - HSkMC [nTPM]":"28.6","Cell RNA - hTCEpi [nTPM]":"44.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"62.0","Cell RNA - hTERT-HME1 [nTPM]":"54.8","Cell RNA - hTERT-RPE1 [nTPM]":"44.1","Cell RNA - HUVEC TERT2 [nTPM]":"71.5","Cell RNA - JURKAT [nTPM]":"82.7","Cell RNA - K-562 [nTPM]":"138.6","Cell RNA - Karpas-707 [nTPM]":"135.5","Cell RNA - LHCN-M2 [nTPM]":"69.2","Cell RNA - MCF7 [nTPM]":"59.7","Cell RNA - MOLT-4 [nTPM]":"196.7","Cell RNA - NB-4 [nTPM]":"83.6","Cell RNA - NTERA-2 [nTPM]":"82.0","Cell RNA - OE19 [nTPM]":"117.4","Cell RNA - PC-3 [nTPM]":"102.8","Cell RNA - REH [nTPM]":"170.3","Cell RNA - RH-30 [nTPM]":"99.9","Cell RNA - RPMI-8226 [nTPM]":"120.3","Cell RNA - RPTEC TERT1 [nTPM]":"46.9","Cell RNA - RT4 [nTPM]":"93.7","Cell RNA - SCLC-21H [nTPM]":"96.2","Cell RNA - SH-SY5Y [nTPM]":"68.8","Cell RNA - SiHa [nTPM]":"88.2","Cell RNA - SK-BR-3 [nTPM]":"103.8","Cell RNA - SK-MEL-30 [nTPM]":"46.3","Cell RNA - SuSa [nTPM]":"63.8","Cell RNA - T-47d [nTPM]":"78.8","Cell RNA - THP-1 [nTPM]":"51.5","Cell RNA - TIME [nTPM]":"53.0","Cell RNA - U-138 MG [nTPM]":"150.2","Cell RNA - U-2 OS [nTPM]":"85.3","Cell RNA - U-2197 [nTPM]":"49.1","Cell RNA - U-251 MG [nTPM]":"155.4","Cell RNA - U-266\/70 [nTPM]":"96.3","Cell RNA - U-266\/84 [nTPM]":"295.9","Cell RNA - U-698 [nTPM]":"132.5","Cell RNA - U-87 MG [nTPM]":"62.2","Cell RNA - U-937 [nTPM]":"90.1","Cell RNA - WM-115 [nTPM]":"113.9","Blood RNA - basophil [nTPM]":"12.3","Blood RNA - classical monocyte [nTPM]":"33.4","Blood RNA - eosinophil [nTPM]":"6.7","Blood RNA - gdT-cell [nTPM]":"17.7","Blood RNA - intermediate monocyte [nTPM]":"34.7","Blood RNA - MAIT T-cell [nTPM]":"24.1","Blood RNA - memory B-cell [nTPM]":"15.1","Blood RNA - memory CD4 T-cell [nTPM]":"17.6","Blood RNA - memory CD8 T-cell [nTPM]":"19.6","Blood RNA - myeloid DC [nTPM]":"33.1","Blood RNA - naive B-cell [nTPM]":"14.9","Blood RNA - naive CD4 T-cell [nTPM]":"11.9","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"5.2","Blood RNA - NK-cell [nTPM]":"22.0","Blood RNA - non-classical monocyte [nTPM]":"20.1","Blood RNA - plasmacytoid DC [nTPM]":"29.0","Blood RNA - T-reg [nTPM]":"17.2","Blood RNA - total PBMC [nTPM]":"22.1","Brain RNA - amygdala [nTPM]":"14.2","Brain RNA - basal ganglia [nTPM]":"13.2","Brain RNA - cerebellum [nTPM]":"18.4","Brain RNA - cerebral cortex [nTPM]":"15.9","Brain RNA - hippocampal formation [nTPM]":"13.9","Brain RNA - hypothalamus [nTPM]":"15.7","Brain RNA - medulla oblongata [nTPM]":"15.5","Brain RNA - midbrain [nTPM]":"14.2","Brain RNA - pons [nTPM]":"15.8","Brain RNA - spinal cord [nTPM]":"13.6","Brain RNA - thalamus [nTPM]":"14.7","Brain RNA - white matter [nTPM]":"16.9","Single Cell Type RNA - Adipocytes [nTPM]":"16.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"28.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"11.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"18.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.0","Single Cell Type RNA - dendritic cells [nTPM]":"24.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"23.7","Single Cell Type RNA - Early spermatids [nTPM]":"113.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.9","Single Cell Type RNA - Endothelial cells [nTPM]":"27.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.6","Single Cell Type RNA - Erythroid cells [nTPM]":"39.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.4","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.6","Single Cell Type RNA - granulocytes [nTPM]":"23.4","Single Cell Type RNA - Granulosa cells [nTPM]":"30.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"13.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.5","Single Cell Type RNA - Horizontal cells [nTPM]":"63.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"36.1","Single Cell Type RNA - Langerhans cells [nTPM]":"119.2","Single Cell Type RNA - Late spermatids [nTPM]":"315.1","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"41.5","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"77.1","Single Cell Type RNA - Muller glia cells [nTPM]":"19.1","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.9","Single Cell Type RNA - Paneth cells [nTPM]":"22.8","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"23.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.0","Single Cell Type RNA - Spermatocytes [nTPM]":"71.0","Single Cell Type RNA - Spermatogonia [nTPM]":"39.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - T-cells [nTPM]":"24.4","Single Cell Type RNA - Theca cells [nTPM]":"17.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.4","Single Cell Type RNA - Urothelial cells [nTPM]":"16.6"},{"Gene":"NYX","Gene synonym":["CLRP","CSNB1","CSNB1A","CSNB4"],"Ensembl":"ENSG00000188937","Gene description":"Nyctalopin","Uniprot":["Q9GZU5"],"Chromosome":"X","Position":"41447343-41475710","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"13.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HDLM-2":"2.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-4"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.5","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"13.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"OCLN","Gene synonym":["PPP1R115"],"Ensembl":"ENSG00000197822","Gene description":"Occludin","Uniprot":["Q16625"],"Chromosome":"5","Position":"69492292-69558104","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"31.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"109.0","Glandular and luminal cells":"119.7","Urothelial cells":"224.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"2.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"23.3","CAPAN-2":"39.8","HaCaT":"33.4","RPTEC TERT1":"25.7","SK-BR-3":"27.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005933","CAB013075","CAB068212","CAB068213","CAB068214"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB013075":"AB_2533101","CAB068212":"AB_2665711","CAB068213":"AB_2665712","CAB068214":"AB_2665713","HPA005933":"AB_1079520"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.59e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"22.2","Tissue RNA - colon [nTPM]":"11.0","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"11.6","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"11.0","Tissue RNA - liver [nTPM]":"18.8","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"9.3","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"20.2","Tissue RNA - parathyroid gland [nTPM]":"8.3","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"8.3","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"11.2","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"11.3","Tissue RNA - small intestine [nTPM]":"10.0","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"31.4","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"7.4","Cell RNA - A-431 [nTPM]":"23.3","Cell RNA - A549 [nTPM]":"4.5","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"15.1","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.3","Cell RNA - CACO-2 [nTPM]":"20.7","Cell RNA - CAPAN-2 [nTPM]":"39.8","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1.1","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"33.4","Cell RNA - HAP1 [nTPM]":"7.2","Cell RNA - HBEC3-KT [nTPM]":"4.3","Cell RNA - HBF TERT88 [nTPM]":"7.8","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"9.8","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"6.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.1","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.6","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"3.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"22.4","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"8.0","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"6.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"25.7","Cell RNA - RT4 [nTPM]":"22.2","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"2.8","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"27.2","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"14.7","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"7.7","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"9.3","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"8.3","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"7.4","Single Cell Type RNA - Adipocytes [nTPM]":"4.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"109.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"67.3","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"3.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"60.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"51.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.3","Single Cell Type RNA - dendritic cells [nTPM]":"3.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"94.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"65.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"78.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.3","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"61.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.5","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"119.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"48.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"45.1","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.6","Single Cell Type RNA - Paneth cells [nTPM]":"61.8","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"101.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"42.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"63.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"8.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.4","Single Cell Type RNA - T-cells [nTPM]":"4.3","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.9","Single Cell Type RNA - Urothelial cells [nTPM]":"224.0"},{"Gene":"OFD1","Gene synonym":["71-7A","CXorf5","JBTS10","RP23"],"Ensembl":"ENSG00000046651","Gene description":"OFD1 centriole and centriolar satellite protein","Uniprot":["O75665"],"Chromosome":"X","Position":"13734745-13769357","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"64.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"64.2"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031102","HPA031103","HPA031104"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA031102":"AB_10670836","HPA031103":"AB_10602188","HPA031104":"AB_10669655"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.62e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-7"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"11.7","Tissue RNA - basal ganglia [nTPM]":"8.7","Tissue RNA - bone marrow [nTPM]":"15.6","Tissue RNA - breast [nTPM]":"14.6","Tissue RNA - cerebellum [nTPM]":"10.8","Tissue RNA - cerebral cortex [nTPM]":"9.8","Tissue RNA - cervix [nTPM]":"11.2","Tissue RNA - choroid plexus [nTPM]":"10.1","Tissue RNA - colon [nTPM]":"9.4","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"11.5","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"5.9","Tissue RNA - hippocampal formation [nTPM]":"8.2","Tissue RNA - hypothalamus [nTPM]":"9.4","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"7.2","Tissue RNA - lung [nTPM]":"9.2","Tissue RNA - lymph node [nTPM]":"19.1","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"11.2","Tissue RNA - pancreas [nTPM]":"11.2","Tissue RNA - parathyroid gland [nTPM]":"15.3","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"11.7","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"11.2","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"6.5","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"11.8","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"7.6","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"12.2","Tissue RNA - testis [nTPM]":"9.9","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"12.9","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"16.8","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"10.0","Cell RNA - A-431 [nTPM]":"16.0","Cell RNA - A549 [nTPM]":"7.1","Cell RNA - AF22 [nTPM]":"10.3","Cell RNA - AN3-CA [nTPM]":"18.4","Cell RNA - ASC diff [nTPM]":"8.4","Cell RNA - ASC TERT1 [nTPM]":"13.0","Cell RNA - BEWO [nTPM]":"7.7","Cell RNA - BJ [nTPM]":"4.9","Cell RNA - BJ hTERT+ [nTPM]":"11.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.3","Cell RNA - CACO-2 [nTPM]":"12.8","Cell RNA - CAPAN-2 [nTPM]":"17.7","Cell RNA - Daudi [nTPM]":"23.2","Cell RNA - EFO-21 [nTPM]":"12.5","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"10.6","Cell RNA - HaCaT [nTPM]":"15.3","Cell RNA - HAP1 [nTPM]":"7.5","Cell RNA - HBEC3-KT [nTPM]":"13.7","Cell RNA - HBF TERT88 [nTPM]":"9.2","Cell RNA - HDLM-2 [nTPM]":"11.6","Cell RNA - HEK 293 [nTPM]":"18.9","Cell RNA - HEL [nTPM]":"10.8","Cell RNA - HeLa [nTPM]":"22.3","Cell RNA - Hep G2 [nTPM]":"10.8","Cell RNA - HHSteC [nTPM]":"6.4","Cell RNA - HL-60 [nTPM]":"14.4","Cell RNA - HMC-1 [nTPM]":"19.1","Cell RNA - HSkMC [nTPM]":"10.4","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.9","Cell RNA - hTERT-HME1 [nTPM]":"12.7","Cell RNA - hTERT-RPE1 [nTPM]":"10.6","Cell RNA - HUVEC TERT2 [nTPM]":"6.4","Cell RNA - JURKAT [nTPM]":"4.2","Cell RNA - K-562 [nTPM]":"16.5","Cell RNA - Karpas-707 [nTPM]":"20.4","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"12.6","Cell RNA - MOLT-4 [nTPM]":"9.9","Cell RNA - NB-4 [nTPM]":"17.3","Cell RNA - NTERA-2 [nTPM]":"10.8","Cell RNA - OE19 [nTPM]":"5.8","Cell RNA - PC-3 [nTPM]":"10.2","Cell RNA - REH [nTPM]":"24.9","Cell RNA - RH-30 [nTPM]":"11.9","Cell RNA - RPMI-8226 [nTPM]":"46.6","Cell RNA - RPTEC TERT1 [nTPM]":"8.9","Cell RNA - RT4 [nTPM]":"13.5","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"16.6","Cell RNA - SiHa [nTPM]":"23.2","Cell RNA - SK-BR-3 [nTPM]":"18.5","Cell RNA - SK-MEL-30 [nTPM]":"11.6","Cell RNA - SuSa [nTPM]":"22.7","Cell RNA - T-47d [nTPM]":"17.5","Cell RNA - THP-1 [nTPM]":"13.0","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"10.0","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"12.1","Cell RNA - U-251 MG [nTPM]":"6.3","Cell RNA - U-266\/70 [nTPM]":"15.1","Cell RNA - U-266\/84 [nTPM]":"15.1","Cell RNA - U-698 [nTPM]":"26.9","Cell RNA - U-87 MG [nTPM]":"8.3","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"8.3","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"6.2","Blood RNA - gdT-cell [nTPM]":"11.6","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"13.4","Blood RNA - memory B-cell [nTPM]":"13.7","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"14.2","Blood RNA - myeloid DC [nTPM]":"3.8","Blood RNA - naive B-cell [nTPM]":"15.4","Blood RNA - naive CD4 T-cell [nTPM]":"8.3","Blood RNA - naive CD8 T-cell [nTPM]":"12.5","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"14.1","Blood RNA - non-classical monocyte [nTPM]":"3.1","Blood RNA - plasmacytoid DC [nTPM]":"64.2","Blood RNA - T-reg [nTPM]":"8.6","Blood RNA - total PBMC [nTPM]":"4.4","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"8.7","Brain RNA - cerebellum [nTPM]":"10.8","Brain RNA - cerebral cortex [nTPM]":"9.8","Brain RNA - hippocampal formation [nTPM]":"8.2","Brain RNA - hypothalamus [nTPM]":"9.4","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"10.0","Single Cell Type RNA - Adipocytes [nTPM]":"40.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"64.1","Single Cell Type RNA - Astrocytes [nTPM]":"60.4","Single Cell Type RNA - B-cells [nTPM]":"90.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"89.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"51.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"47.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"64.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"66.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"89.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.5","Single Cell Type RNA - dendritic cells [nTPM]":"219.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"82.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"60.2","Single Cell Type RNA - Early spermatids [nTPM]":"178.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"232.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.0","Single Cell Type RNA - Endothelial cells [nTPM]":"39.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"48.6","Single Cell Type RNA - Erythroid cells [nTPM]":"30.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.4","Single Cell Type RNA - Fibroblasts [nTPM]":"31.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"58.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"180.8","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"41.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.7","Single Cell Type RNA - Hepatocytes [nTPM]":"13.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.2","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"60.3","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"19.8","Single Cell Type RNA - Langerhans cells [nTPM]":"43.0","Single Cell Type RNA - Late spermatids [nTPM]":"187.4","Single Cell Type RNA - Leydig cells [nTPM]":"52.2","Single Cell Type RNA - Macrophages [nTPM]":"35.1","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"38.2","Single Cell Type RNA - Muller glia cells [nTPM]":"41.3","Single Cell Type RNA - NK-cells [nTPM]":"145.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"76.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"64.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"60.7","Single Cell Type RNA - Paneth cells [nTPM]":"72.9","Single Cell Type RNA - Peritubular cells [nTPM]":"33.8","Single Cell Type RNA - Plasma cells [nTPM]":"50.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"84.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"83.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"81.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"107.2","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.2","Single Cell Type RNA - Spermatocytes [nTPM]":"72.7","Single Cell Type RNA - Spermatogonia [nTPM]":"59.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"87.0","Single Cell Type RNA - T-cells [nTPM]":"102.2","Single Cell Type RNA - Theca cells [nTPM]":"30.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.2","Single Cell Type RNA - Urothelial cells [nTPM]":"82.8"},{"Gene":"OPA1","Gene synonym":["FLJ12460","KIAA0567","MGM1","NPG","NTG"],"Ensembl":"ENSG00000198836","Gene description":"OPA1 mitochondrial dynamin like GTPase","Uniprot":["O60313"],"Chromosome":"3","Position":"193593144-193697811","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis","Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":["Cardiomyopathy","Deafness","Disease variant","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"135.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036926","HPA036927"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA036926":"AB_10671247","HPA036927":"AB_2675388"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.44e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.84e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.0","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"14.3","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"17.4","Tissue RNA - bone marrow [nTPM]":"25.6","Tissue RNA - breast [nTPM]":"12.8","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"19.5","Tissue RNA - cervix [nTPM]":"10.4","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"18.9","Tissue RNA - duodenum [nTPM]":"16.8","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"9.1","Tissue RNA - esophagus [nTPM]":"14.6","Tissue RNA - fallopian tube [nTPM]":"8.1","Tissue RNA - gallbladder [nTPM]":"10.2","Tissue RNA - heart muscle [nTPM]":"39.3","Tissue RNA - hippocampal formation [nTPM]":"18.6","Tissue RNA - hypothalamus [nTPM]":"17.4","Tissue RNA - kidney [nTPM]":"18.3","Tissue RNA - liver [nTPM]":"20.9","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"11.8","Tissue RNA - medulla oblongata [nTPM]":"16.4","Tissue RNA - midbrain [nTPM]":"15.4","Tissue RNA - ovary [nTPM]":"8.4","Tissue RNA - pancreas [nTPM]":"10.1","Tissue RNA - parathyroid gland [nTPM]":"23.1","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"16.8","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"16.6","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"11.7","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"24.2","Tissue RNA - skin 1 [nTPM]":"11.9","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"13.5","Tissue RNA - spinal cord [nTPM]":"12.4","Tissue RNA - spleen [nTPM]":"9.3","Tissue RNA - stomach 1 [nTPM]":"14.6","Tissue RNA - testis [nTPM]":"6.3","Tissue RNA - thalamus [nTPM]":"15.2","Tissue RNA - thymus [nTPM]":"12.7","Tissue RNA - thyroid gland [nTPM]":"13.9","Tissue RNA - tongue [nTPM]":"44.5","Tissue RNA - tonsil [nTPM]":"12.4","Tissue RNA - urinary bladder [nTPM]":"13.0","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"13.7","Cell RNA - A-431 [nTPM]":"58.9","Cell RNA - A549 [nTPM]":"18.8","Cell RNA - AF22 [nTPM]":"18.2","Cell RNA - AN3-CA [nTPM]":"20.2","Cell RNA - ASC diff [nTPM]":"15.8","Cell RNA - ASC TERT1 [nTPM]":"25.0","Cell RNA - BEWO [nTPM]":"19.3","Cell RNA - BJ [nTPM]":"27.5","Cell RNA - BJ hTERT+ [nTPM]":"26.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.0","Cell RNA - CACO-2 [nTPM]":"45.2","Cell RNA - CAPAN-2 [nTPM]":"19.3","Cell RNA - Daudi [nTPM]":"38.6","Cell RNA - EFO-21 [nTPM]":"58.1","Cell RNA - fHDF\/TERT166 [nTPM]":"27.0","Cell RNA - GAMG [nTPM]":"27.3","Cell RNA - HaCaT [nTPM]":"37.3","Cell RNA - HAP1 [nTPM]":"32.7","Cell RNA - HBEC3-KT [nTPM]":"31.7","Cell RNA - HBF TERT88 [nTPM]":"53.5","Cell RNA - HDLM-2 [nTPM]":"46.5","Cell RNA - HEK 293 [nTPM]":"25.7","Cell RNA - HEL [nTPM]":"67.9","Cell RNA - HeLa [nTPM]":"16.7","Cell RNA - Hep G2 [nTPM]":"23.1","Cell RNA - HHSteC [nTPM]":"24.9","Cell RNA - HL-60 [nTPM]":"55.8","Cell RNA - HMC-1 [nTPM]":"29.8","Cell RNA - HSkMC [nTPM]":"28.4","Cell RNA - hTCEpi [nTPM]":"27.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.0","Cell RNA - hTERT-HME1 [nTPM]":"40.9","Cell RNA - hTERT-RPE1 [nTPM]":"18.5","Cell RNA - HUVEC TERT2 [nTPM]":"26.2","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"28.4","Cell RNA - Karpas-707 [nTPM]":"37.0","Cell RNA - LHCN-M2 [nTPM]":"30.2","Cell RNA - MCF7 [nTPM]":"46.5","Cell RNA - MOLT-4 [nTPM]":"21.9","Cell RNA - NB-4 [nTPM]":"30.9","Cell RNA - NTERA-2 [nTPM]":"25.8","Cell RNA - OE19 [nTPM]":"33.9","Cell RNA - PC-3 [nTPM]":"59.9","Cell RNA - REH [nTPM]":"27.8","Cell RNA - RH-30 [nTPM]":"40.1","Cell RNA - RPMI-8226 [nTPM]":"41.6","Cell RNA - RPTEC TERT1 [nTPM]":"22.7","Cell RNA - RT4 [nTPM]":"36.1","Cell RNA - SCLC-21H [nTPM]":"39.8","Cell RNA - SH-SY5Y [nTPM]":"24.2","Cell RNA - SiHa [nTPM]":"41.8","Cell RNA - SK-BR-3 [nTPM]":"46.3","Cell RNA - SK-MEL-30 [nTPM]":"29.5","Cell RNA - SuSa [nTPM]":"14.1","Cell RNA - T-47d [nTPM]":"60.3","Cell RNA - THP-1 [nTPM]":"43.5","Cell RNA - TIME [nTPM]":"26.3","Cell RNA - U-138 MG [nTPM]":"27.7","Cell RNA - U-2 OS [nTPM]":"20.8","Cell RNA - U-2197 [nTPM]":"29.3","Cell RNA - U-251 MG [nTPM]":"58.7","Cell RNA - U-266\/70 [nTPM]":"33.1","Cell RNA - U-266\/84 [nTPM]":"41.3","Cell RNA - U-698 [nTPM]":"74.0","Cell RNA - U-87 MG [nTPM]":"30.5","Cell RNA - U-937 [nTPM]":"43.7","Cell RNA - WM-115 [nTPM]":"28.4","Blood RNA - basophil [nTPM]":"9.7","Blood RNA - classical monocyte [nTPM]":"7.3","Blood RNA - eosinophil [nTPM]":"7.1","Blood RNA - gdT-cell [nTPM]":"5.8","Blood RNA - intermediate monocyte [nTPM]":"8.2","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"6.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.6","Blood RNA - myeloid DC [nTPM]":"7.8","Blood RNA - naive B-cell [nTPM]":"5.1","Blood RNA - naive CD4 T-cell [nTPM]":"5.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"17.3","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"6.6","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"14.3","Brain RNA - basal ganglia [nTPM]":"17.4","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"19.5","Brain RNA - hippocampal formation [nTPM]":"18.6","Brain RNA - hypothalamus [nTPM]":"17.4","Brain RNA - medulla oblongata [nTPM]":"16.4","Brain RNA - midbrain [nTPM]":"15.4","Brain RNA - pons [nTPM]":"16.8","Brain RNA - spinal cord [nTPM]":"12.4","Brain RNA - thalamus [nTPM]":"15.2","Brain RNA - white matter [nTPM]":"13.7","Single Cell Type RNA - Adipocytes [nTPM]":"24.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.0","Single Cell Type RNA - Astrocytes [nTPM]":"72.1","Single Cell Type RNA - B-cells [nTPM]":"27.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"19.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"135.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"20.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.0","Single Cell Type RNA - dendritic cells [nTPM]":"24.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"7.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.2","Single Cell Type RNA - Endothelial cells [nTPM]":"23.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.4","Single Cell Type RNA - Erythroid cells [nTPM]":"86.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"106.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.9","Single Cell Type RNA - Fibroblasts [nTPM]":"24.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.1","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"25.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"39.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.9","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"106.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"25.6","Single Cell Type RNA - Langerhans cells [nTPM]":"14.7","Single Cell Type RNA - Late spermatids [nTPM]":"13.5","Single Cell Type RNA - Leydig cells [nTPM]":"15.8","Single Cell Type RNA - Macrophages [nTPM]":"28.1","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"22.9","Single Cell Type RNA - Muller glia cells [nTPM]":"14.6","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"87.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"98.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.9","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"29.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"34.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.2","Single Cell Type RNA - Spermatocytes [nTPM]":"15.1","Single Cell Type RNA - Spermatogonia [nTPM]":"16.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.9","Single Cell Type RNA - T-cells [nTPM]":"22.3","Single Cell Type RNA - Theca cells [nTPM]":"28.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.7","Single Cell Type RNA - Urothelial cells [nTPM]":"22.1"},{"Gene":"OPA3","Gene synonym":["FLJ22187","MGA3"],"Ensembl":"ENSG00000125741","Gene description":"Outer mitochondrial membrane lipid metabolism regulator OPA3","Uniprot":["Q9H6K4"],"Chromosome":"19","Position":"45527427-45602212","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044881"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA044881":"AB_10964052"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.60e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.30e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"3.3","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"3.5","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"4.0","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"5.8","Tissue RNA - fallopian tube [nTPM]":"3.4","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"10.5","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"7.4","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"4.0","Tissue RNA - ovary [nTPM]":"3.4","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"12.0","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"4.4","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"3.8","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"11.1","Tissue RNA - skin 1 [nTPM]":"5.8","Tissue RNA - small intestine [nTPM]":"5.0","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"5.8","Tissue RNA - stomach 1 [nTPM]":"4.9","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"4.6","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"12.9","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"15.2","Cell RNA - A549 [nTPM]":"18.9","Cell RNA - AF22 [nTPM]":"7.4","Cell RNA - AN3-CA [nTPM]":"7.3","Cell RNA - ASC diff [nTPM]":"4.8","Cell RNA - ASC TERT1 [nTPM]":"5.9","Cell RNA - BEWO [nTPM]":"11.3","Cell RNA - BJ [nTPM]":"9.7","Cell RNA - BJ hTERT+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.7","Cell RNA - CACO-2 [nTPM]":"8.8","Cell RNA - CAPAN-2 [nTPM]":"10.5","Cell RNA - Daudi [nTPM]":"13.0","Cell RNA - EFO-21 [nTPM]":"6.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"11.5","Cell RNA - HaCaT [nTPM]":"12.0","Cell RNA - HAP1 [nTPM]":"12.5","Cell RNA - HBEC3-KT [nTPM]":"13.3","Cell RNA - HBF TERT88 [nTPM]":"8.9","Cell RNA - HDLM-2 [nTPM]":"24.0","Cell RNA - HEK 293 [nTPM]":"12.6","Cell RNA - HEL [nTPM]":"20.1","Cell RNA - HeLa [nTPM]":"10.8","Cell RNA - Hep G2 [nTPM]":"9.1","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"14.1","Cell RNA - HMC-1 [nTPM]":"25.0","Cell RNA - HSkMC [nTPM]":"8.9","Cell RNA - hTCEpi [nTPM]":"10.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.2","Cell RNA - hTERT-HME1 [nTPM]":"12.2","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"7.3","Cell RNA - JURKAT [nTPM]":"7.6","Cell RNA - K-562 [nTPM]":"17.5","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"6.9","Cell RNA - MCF7 [nTPM]":"9.3","Cell RNA - MOLT-4 [nTPM]":"11.3","Cell RNA - NB-4 [nTPM]":"5.8","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"12.6","Cell RNA - PC-3 [nTPM]":"12.9","Cell RNA - REH [nTPM]":"10.9","Cell RNA - RH-30 [nTPM]":"6.7","Cell RNA - RPMI-8226 [nTPM]":"7.1","Cell RNA - RPTEC TERT1 [nTPM]":"8.0","Cell RNA - RT4 [nTPM]":"26.9","Cell RNA - SCLC-21H [nTPM]":"5.5","Cell RNA - SH-SY5Y [nTPM]":"6.6","Cell RNA - SiHa [nTPM]":"12.4","Cell RNA - SK-BR-3 [nTPM]":"11.3","Cell RNA - SK-MEL-30 [nTPM]":"5.2","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"6.3","Cell RNA - THP-1 [nTPM]":"8.0","Cell RNA - TIME [nTPM]":"15.9","Cell RNA - U-138 MG [nTPM]":"8.5","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"7.1","Cell RNA - U-251 MG [nTPM]":"16.7","Cell RNA - U-266\/70 [nTPM]":"9.5","Cell RNA - U-266\/84 [nTPM]":"19.1","Cell RNA - U-698 [nTPM]":"10.6","Cell RNA - U-87 MG [nTPM]":"8.2","Cell RNA - U-937 [nTPM]":"10.1","Cell RNA - WM-115 [nTPM]":"13.1","Blood RNA - basophil [nTPM]":"5.6","Blood RNA - classical monocyte [nTPM]":"5.3","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"7.8","Blood RNA - MAIT T-cell [nTPM]":"3.6","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"3.1","Blood RNA - myeloid DC [nTPM]":"5.6","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"7.8","Blood RNA - non-classical monocyte [nTPM]":"10.5","Blood RNA - plasmacytoid DC [nTPM]":"5.1","Blood RNA - T-reg [nTPM]":"4.8","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"3.3","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"4.0","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"11.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.7","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"23.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"11.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.6","Single Cell Type RNA - dendritic cells [nTPM]":"15.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"18.4","Single Cell Type RNA - Early spermatids [nTPM]":"18.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.8","Single Cell Type RNA - Endothelial cells [nTPM]":"15.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.8","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.8","Single Cell Type RNA - Fibroblasts [nTPM]":"10.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.1","Single Cell Type RNA - granulocytes [nTPM]":"15.9","Single Cell Type RNA - Granulosa cells [nTPM]":"8.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"21.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.3","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.5","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"11.4","Single Cell Type RNA - Langerhans cells [nTPM]":"28.3","Single Cell Type RNA - Late spermatids [nTPM]":"20.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"17.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"19.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.1","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.2","Single Cell Type RNA - Paneth cells [nTPM]":"19.2","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"11.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.6","Single Cell Type RNA - Spermatocytes [nTPM]":"23.9","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.3","Single Cell Type RNA - T-cells [nTPM]":"14.4","Single Cell Type RNA - Theca cells [nTPM]":"19.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.6","Single Cell Type RNA - Urothelial cells [nTPM]":"16.7"},{"Gene":"OPN1LW","Gene synonym":["CBBM","CBP","COD5","RCP"],"Ensembl":"ENSG00000102076","Gene description":"Opsin 1, long wave sensitive","Uniprot":["P04000"],"Chromosome":"X","Position":"154144243-154159032","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"2568","RNA tissue specific nTPM":{"retina":"256.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"725.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"256.7","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"9.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"725.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"OPN1MW","Gene synonym":["CBBM","CBD","COD5","GCP","OPN1MW1"],"Ensembl":"ENSG00000268221","Gene description":"Opsin 1, medium wave sensitive","Uniprot":["P04001"],"Chromosome":"X","Position":"154182596-154196861","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"133","RNA tissue specific nTPM":{"retina":"13.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"111","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"33.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"13.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"OPN1SW","Gene synonym":["BCP","BOP","CBT"],"Ensembl":"ENSG00000128617","Gene description":"Opsin 1, short wave sensitive","Uniprot":["P03999"],"Chromosome":"7","Position":"128772485-128775794","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"84","RNA tissue specific nTPM":{"retina":"41.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"41.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"LHCN-M2":"1.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013562","HPA014083"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytokinetic bridge","Cytosol"],"Antibody RRID":{"HPA013562":"AB_2668850","HPA014083":"AB_2668938"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.50e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.98e-8"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.33e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"41.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"OPTN","Gene synonym":["FIP-2","FIP2","GLC1E","HIP7","HYPL","NRP","TFIIIA-INTP"],"Ensembl":"ENSG00000123240","Gene description":"Optineurin","Uniprot":["Q96CV9"],"Chromosome":"10","Position":"13099449-13138308","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Glaucoma","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skeletal muscle":"879.4","tongue":"394.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"933.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003279","HPA003360","CAB019303"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB019303":null,"HPA003279":"AB_1079527","HPA003360":"AB_1079528"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"92.7","Tissue RNA - adrenal gland [nTPM]":"90.4","Tissue RNA - amygdala [nTPM]":"45.7","Tissue RNA - appendix [nTPM]":"35.8","Tissue RNA - basal ganglia [nTPM]":"53.5","Tissue RNA - bone marrow [nTPM]":"50.1","Tissue RNA - breast [nTPM]":"64.0","Tissue RNA - cerebellum [nTPM]":"45.9","Tissue RNA - cerebral cortex [nTPM]":"55.9","Tissue RNA - cervix [nTPM]":"52.3","Tissue RNA - choroid plexus [nTPM]":"36.8","Tissue RNA - colon [nTPM]":"55.4","Tissue RNA - duodenum [nTPM]":"63.2","Tissue RNA - endometrium 1 [nTPM]":"39.7","Tissue RNA - epididymis [nTPM]":"21.9","Tissue RNA - esophagus [nTPM]":"61.8","Tissue RNA - fallopian tube [nTPM]":"37.7","Tissue RNA - gallbladder [nTPM]":"41.6","Tissue RNA - heart muscle [nTPM]":"105.7","Tissue RNA - hippocampal formation [nTPM]":"54.9","Tissue RNA - hypothalamus [nTPM]":"49.2","Tissue RNA - kidney [nTPM]":"72.3","Tissue RNA - liver [nTPM]":"73.8","Tissue RNA - lung [nTPM]":"58.9","Tissue RNA - lymph node [nTPM]":"45.7","Tissue RNA - medulla oblongata [nTPM]":"48.0","Tissue RNA - midbrain [nTPM]":"53.9","Tissue RNA - ovary [nTPM]":"92.1","Tissue RNA - pancreas [nTPM]":"35.4","Tissue RNA - parathyroid gland [nTPM]":"33.1","Tissue RNA - pituitary gland [nTPM]":"33.8","Tissue RNA - placenta [nTPM]":"57.5","Tissue RNA - pons [nTPM]":"52.9","Tissue RNA - prostate [nTPM]":"34.1","Tissue RNA - rectum [nTPM]":"57.2","Tissue RNA - retina [nTPM]":"48.8","Tissue RNA - salivary gland [nTPM]":"46.3","Tissue RNA - seminal vesicle [nTPM]":"41.4","Tissue RNA - skeletal muscle [nTPM]":"879.4","Tissue RNA - skin 1 [nTPM]":"77.9","Tissue RNA - small intestine [nTPM]":"69.6","Tissue RNA - smooth muscle [nTPM]":"43.4","Tissue RNA - spinal cord [nTPM]":"44.3","Tissue RNA - spleen [nTPM]":"57.3","Tissue RNA - stomach 1 [nTPM]":"56.1","Tissue RNA - testis [nTPM]":"72.8","Tissue RNA - thalamus [nTPM]":"45.4","Tissue RNA - thymus [nTPM]":"30.1","Tissue RNA - thyroid gland [nTPM]":"27.1","Tissue RNA - tongue [nTPM]":"394.5","Tissue RNA - tonsil [nTPM]":"37.6","Tissue RNA - urinary bladder [nTPM]":"43.8","Tissue RNA - vagina [nTPM]":"56.3","Tissue RNA - white matter [nTPM]":"49.0","Cell RNA - A-431 [nTPM]":"83.3","Cell RNA - A549 [nTPM]":"23.1","Cell RNA - AF22 [nTPM]":"12.8","Cell RNA - AN3-CA [nTPM]":"17.8","Cell RNA - ASC diff [nTPM]":"171.4","Cell RNA - ASC TERT1 [nTPM]":"175.6","Cell RNA - BEWO [nTPM]":"15.2","Cell RNA - BJ [nTPM]":"97.6","Cell RNA - BJ hTERT+ [nTPM]":"110.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"72.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"119.0","Cell RNA - CACO-2 [nTPM]":"41.1","Cell RNA - CAPAN-2 [nTPM]":"108.1","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"37.6","Cell RNA - fHDF\/TERT166 [nTPM]":"134.3","Cell RNA - GAMG [nTPM]":"113.2","Cell RNA - HaCaT [nTPM]":"75.6","Cell RNA - HAP1 [nTPM]":"17.3","Cell RNA - HBEC3-KT [nTPM]":"93.5","Cell RNA - HBF TERT88 [nTPM]":"54.8","Cell RNA - HDLM-2 [nTPM]":"192.9","Cell RNA - HEK 293 [nTPM]":"9.2","Cell RNA - HEL [nTPM]":"17.2","Cell RNA - HeLa [nTPM]":"32.1","Cell RNA - Hep G2 [nTPM]":"22.0","Cell RNA - HHSteC [nTPM]":"175.4","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"59.5","Cell RNA - HSkMC [nTPM]":"94.6","Cell RNA - hTCEpi [nTPM]":"72.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"69.2","Cell RNA - hTERT-HME1 [nTPM]":"71.8","Cell RNA - hTERT-RPE1 [nTPM]":"177.9","Cell RNA - HUVEC TERT2 [nTPM]":"62.4","Cell RNA - JURKAT [nTPM]":"23.8","Cell RNA - K-562 [nTPM]":"21.5","Cell RNA - Karpas-707 [nTPM]":"123.7","Cell RNA - LHCN-M2 [nTPM]":"98.7","Cell RNA - MCF7 [nTPM]":"17.6","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"2.3","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"22.4","Cell RNA - PC-3 [nTPM]":"10.3","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"25.5","Cell RNA - RPMI-8226 [nTPM]":"8.5","Cell RNA - RPTEC TERT1 [nTPM]":"87.9","Cell RNA - RT4 [nTPM]":"57.6","Cell RNA - SCLC-21H [nTPM]":"2.8","Cell RNA - SH-SY5Y [nTPM]":"13.6","Cell RNA - SiHa [nTPM]":"84.9","Cell RNA - SK-BR-3 [nTPM]":"25.0","Cell RNA - SK-MEL-30 [nTPM]":"64.3","Cell RNA - SuSa [nTPM]":"49.9","Cell RNA - T-47d [nTPM]":"54.6","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"171.6","Cell RNA - U-138 MG [nTPM]":"58.8","Cell RNA - U-2 OS [nTPM]":"28.9","Cell RNA - U-2197 [nTPM]":"81.0","Cell RNA - U-251 MG [nTPM]":"27.5","Cell RNA - U-266\/70 [nTPM]":"63.3","Cell RNA - U-266\/84 [nTPM]":"23.5","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"88.3","Cell RNA - U-937 [nTPM]":"14.3","Cell RNA - WM-115 [nTPM]":"11.4","Blood RNA - basophil [nTPM]":"47.9","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"56.1","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"43.3","Blood RNA - memory B-cell [nTPM]":"18.0","Blood RNA - memory CD4 T-cell [nTPM]":"71.2","Blood RNA - memory CD8 T-cell [nTPM]":"65.8","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"11.7","Blood RNA - naive CD4 T-cell [nTPM]":"28.0","Blood RNA - naive CD8 T-cell [nTPM]":"34.5","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"51.2","Blood RNA - non-classical monocyte [nTPM]":"3.8","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"109.6","Blood RNA - total PBMC [nTPM]":"30.2","Brain RNA - amygdala [nTPM]":"45.7","Brain RNA - basal ganglia [nTPM]":"53.5","Brain RNA - cerebellum [nTPM]":"45.9","Brain RNA - cerebral cortex [nTPM]":"55.9","Brain RNA - hippocampal formation [nTPM]":"54.9","Brain RNA - hypothalamus [nTPM]":"49.2","Brain RNA - medulla oblongata [nTPM]":"48.0","Brain RNA - midbrain [nTPM]":"53.9","Brain RNA - pons [nTPM]":"52.9","Brain RNA - spinal cord [nTPM]":"44.3","Brain RNA - thalamus [nTPM]":"45.4","Brain RNA - white matter [nTPM]":"49.0","Single Cell Type RNA - Adipocytes [nTPM]":"68.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.4","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"25.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"74.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"46.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"104.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"67.2","Single Cell Type RNA - Bipolar cells [nTPM]":"38.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"237.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"68.6","Single Cell Type RNA - Club cells [nTPM]":"81.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"112.8","Single Cell Type RNA - dendritic cells [nTPM]":"89.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"199.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"135.5","Single Cell Type RNA - Early spermatids [nTPM]":"281.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.6","Single Cell Type RNA - Endothelial cells [nTPM]":"82.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"42.6","Single Cell Type RNA - Erythroid cells [nTPM]":"126.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"114.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.8","Single Cell Type RNA - Fibroblasts [nTPM]":"91.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"88.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.4","Single Cell Type RNA - granulocytes [nTPM]":"70.8","Single Cell Type RNA - Granulosa cells [nTPM]":"92.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.8","Single Cell Type RNA - Hepatocytes [nTPM]":"30.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.6","Single Cell Type RNA - Horizontal cells [nTPM]":"90.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"106.4","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.1","Single Cell Type RNA - Langerhans cells [nTPM]":"26.0","Single Cell Type RNA - Late spermatids [nTPM]":"933.6","Single Cell Type RNA - Leydig cells [nTPM]":"95.7","Single Cell Type RNA - Macrophages [nTPM]":"14.5","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"36.6","Single Cell Type RNA - Muller glia cells [nTPM]":"36.4","Single Cell Type RNA - NK-cells [nTPM]":"119.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"166.3","Single Cell Type RNA - Paneth cells [nTPM]":"186.9","Single Cell Type RNA - Peritubular cells [nTPM]":"103.4","Single Cell Type RNA - Plasma cells [nTPM]":"86.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"92.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"209.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"162.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"73.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"103.4","Single Cell Type RNA - Sertoli cells [nTPM]":"111.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"63.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"106.6","Single Cell Type RNA - Spermatocytes [nTPM]":"102.0","Single Cell Type RNA - Spermatogonia [nTPM]":"13.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"58.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"77.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"75.4","Single Cell Type RNA - T-cells [nTPM]":"107.5","Single Cell Type RNA - Theca cells [nTPM]":"166.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.1","Single Cell Type RNA - Urothelial cells [nTPM]":"75.0"},{"Gene":"OSBPL2","Gene synonym":["DFNA67","KIAA0772","ORP-2"],"Ensembl":"ENSG00000130703","Gene description":"Oxysterol binding protein like 2","Uniprot":["Q9H1P3"],"Chromosome":"20","Position":"62231922-62296213","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"94.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"94.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041127","HPA042659"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041127":"AB_10962008","HPA042659":"AB_10960683"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.6","Tissue RNA - adrenal gland [nTPM]":"15.2","Tissue RNA - amygdala [nTPM]":"21.1","Tissue RNA - appendix [nTPM]":"13.4","Tissue RNA - basal ganglia [nTPM]":"21.2","Tissue RNA - bone marrow [nTPM]":"32.9","Tissue RNA - breast [nTPM]":"18.9","Tissue RNA - cerebellum [nTPM]":"38.9","Tissue RNA - cerebral cortex [nTPM]":"21.4","Tissue RNA - cervix [nTPM]":"21.9","Tissue RNA - choroid plexus [nTPM]":"20.0","Tissue RNA - colon [nTPM]":"24.3","Tissue RNA - duodenum [nTPM]":"22.8","Tissue RNA - endometrium 1 [nTPM]":"14.0","Tissue RNA - epididymis [nTPM]":"15.8","Tissue RNA - esophagus [nTPM]":"40.7","Tissue RNA - fallopian tube [nTPM]":"15.6","Tissue RNA - gallbladder [nTPM]":"20.0","Tissue RNA - heart muscle [nTPM]":"25.4","Tissue RNA - hippocampal formation [nTPM]":"16.6","Tissue RNA - hypothalamus [nTPM]":"20.3","Tissue RNA - kidney [nTPM]":"20.8","Tissue RNA - liver [nTPM]":"18.0","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"14.3","Tissue RNA - medulla oblongata [nTPM]":"23.7","Tissue RNA - midbrain [nTPM]":"24.0","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"39.7","Tissue RNA - parathyroid gland [nTPM]":"26.4","Tissue RNA - pituitary gland [nTPM]":"26.4","Tissue RNA - placenta [nTPM]":"13.7","Tissue RNA - pons [nTPM]":"22.3","Tissue RNA - prostate [nTPM]":"19.8","Tissue RNA - rectum [nTPM]":"22.7","Tissue RNA - retina [nTPM]":"14.5","Tissue RNA - salivary gland [nTPM]":"24.9","Tissue RNA - seminal vesicle [nTPM]":"18.8","Tissue RNA - skeletal muscle [nTPM]":"18.0","Tissue RNA - skin 1 [nTPM]":"43.5","Tissue RNA - small intestine [nTPM]":"21.6","Tissue RNA - smooth muscle [nTPM]":"17.4","Tissue RNA - spinal cord [nTPM]":"19.4","Tissue RNA - spleen [nTPM]":"24.9","Tissue RNA - stomach 1 [nTPM]":"27.9","Tissue RNA - testis [nTPM]":"14.9","Tissue RNA - thalamus [nTPM]":"29.8","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"21.9","Tissue RNA - tongue [nTPM]":"11.9","Tissue RNA - tonsil [nTPM]":"20.4","Tissue RNA - urinary bladder [nTPM]":"23.1","Tissue RNA - vagina [nTPM]":"29.8","Tissue RNA - white matter [nTPM]":"19.4","Cell RNA - A-431 [nTPM]":"23.9","Cell RNA - A549 [nTPM]":"17.0","Cell RNA - AF22 [nTPM]":"19.6","Cell RNA - AN3-CA [nTPM]":"18.3","Cell RNA - ASC diff [nTPM]":"19.4","Cell RNA - ASC TERT1 [nTPM]":"19.1","Cell RNA - BEWO [nTPM]":"18.5","Cell RNA - BJ [nTPM]":"14.2","Cell RNA - BJ hTERT+ [nTPM]":"27.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.1","Cell RNA - CACO-2 [nTPM]":"61.0","Cell RNA - CAPAN-2 [nTPM]":"24.1","Cell RNA - Daudi [nTPM]":"11.5","Cell RNA - EFO-21 [nTPM]":"37.1","Cell RNA - fHDF\/TERT166 [nTPM]":"28.4","Cell RNA - GAMG [nTPM]":"41.8","Cell RNA - HaCaT [nTPM]":"40.7","Cell RNA - HAP1 [nTPM]":"18.9","Cell RNA - HBEC3-KT [nTPM]":"42.4","Cell RNA - HBF TERT88 [nTPM]":"25.7","Cell RNA - HDLM-2 [nTPM]":"13.7","Cell RNA - HEK 293 [nTPM]":"17.7","Cell RNA - HEL [nTPM]":"30.6","Cell RNA - HeLa [nTPM]":"21.5","Cell RNA - Hep G2 [nTPM]":"31.2","Cell RNA - HHSteC [nTPM]":"19.0","Cell RNA - HL-60 [nTPM]":"11.8","Cell RNA - HMC-1 [nTPM]":"26.6","Cell RNA - HSkMC [nTPM]":"17.7","Cell RNA - hTCEpi [nTPM]":"61.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.8","Cell RNA - hTERT-HME1 [nTPM]":"23.3","Cell RNA - hTERT-RPE1 [nTPM]":"22.1","Cell RNA - HUVEC TERT2 [nTPM]":"19.1","Cell RNA - JURKAT [nTPM]":"29.4","Cell RNA - K-562 [nTPM]":"20.3","Cell RNA - Karpas-707 [nTPM]":"21.2","Cell RNA - LHCN-M2 [nTPM]":"13.5","Cell RNA - MCF7 [nTPM]":"19.4","Cell RNA - MOLT-4 [nTPM]":"17.2","Cell RNA - NB-4 [nTPM]":"19.8","Cell RNA - NTERA-2 [nTPM]":"6.4","Cell RNA - OE19 [nTPM]":"43.5","Cell RNA - PC-3 [nTPM]":"15.0","Cell RNA - REH [nTPM]":"15.9","Cell RNA - RH-30 [nTPM]":"23.5","Cell RNA - RPMI-8226 [nTPM]":"15.3","Cell RNA - RPTEC TERT1 [nTPM]":"23.6","Cell RNA - RT4 [nTPM]":"48.2","Cell RNA - SCLC-21H [nTPM]":"25.6","Cell RNA - SH-SY5Y [nTPM]":"16.7","Cell RNA - SiHa [nTPM]":"25.7","Cell RNA - SK-BR-3 [nTPM]":"48.2","Cell RNA - SK-MEL-30 [nTPM]":"24.3","Cell RNA - SuSa [nTPM]":"25.9","Cell RNA - T-47d [nTPM]":"32.1","Cell RNA - THP-1 [nTPM]":"21.0","Cell RNA - TIME [nTPM]":"13.2","Cell RNA - U-138 MG [nTPM]":"23.2","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"24.7","Cell RNA - U-251 MG [nTPM]":"17.3","Cell RNA - U-266\/70 [nTPM]":"24.5","Cell RNA - U-266\/84 [nTPM]":"37.4","Cell RNA - U-698 [nTPM]":"17.5","Cell RNA - U-87 MG [nTPM]":"25.7","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"14.9","Blood RNA - basophil [nTPM]":"16.1","Blood RNA - classical monocyte [nTPM]":"9.2","Blood RNA - eosinophil [nTPM]":"34.5","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"11.7","Blood RNA - MAIT T-cell [nTPM]":"11.4","Blood RNA - memory B-cell [nTPM]":"13.7","Blood RNA - memory CD4 T-cell [nTPM]":"10.5","Blood RNA - memory CD8 T-cell [nTPM]":"13.7","Blood RNA - myeloid DC [nTPM]":"9.9","Blood RNA - naive B-cell [nTPM]":"10.9","Blood RNA - naive CD4 T-cell [nTPM]":"9.5","Blood RNA - naive CD8 T-cell [nTPM]":"11.4","Blood RNA - neutrophil [nTPM]":"94.6","Blood RNA - NK-cell [nTPM]":"16.8","Blood RNA - non-classical monocyte [nTPM]":"9.9","Blood RNA - plasmacytoid DC [nTPM]":"7.1","Blood RNA - T-reg [nTPM]":"17.5","Blood RNA - total PBMC [nTPM]":"10.9","Brain RNA - amygdala [nTPM]":"21.1","Brain RNA - basal ganglia [nTPM]":"21.2","Brain RNA - cerebellum [nTPM]":"38.9","Brain RNA - cerebral cortex [nTPM]":"21.4","Brain RNA - hippocampal formation [nTPM]":"16.6","Brain RNA - hypothalamus [nTPM]":"20.3","Brain RNA - medulla oblongata [nTPM]":"23.7","Brain RNA - midbrain [nTPM]":"24.0","Brain RNA - pons [nTPM]":"22.3","Brain RNA - spinal cord [nTPM]":"19.4","Brain RNA - thalamus [nTPM]":"29.8","Brain RNA - white matter [nTPM]":"19.4","Single Cell Type RNA - Adipocytes [nTPM]":"27.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.3","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"16.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"18.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"28.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.4","Single Cell Type RNA - dendritic cells [nTPM]":"21.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"22.7","Single Cell Type RNA - Early spermatids [nTPM]":"33.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.0","Single Cell Type RNA - Endothelial cells [nTPM]":"18.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"24.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.8","Single Cell Type RNA - Fibroblasts [nTPM]":"17.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.2","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"19.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"14.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.3","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.6","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"11.1","Single Cell Type RNA - Langerhans cells [nTPM]":"8.0","Single Cell Type RNA - Late spermatids [nTPM]":"17.4","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"14.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"16.8","Single Cell Type RNA - Muller glia cells [nTPM]":"18.2","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.8","Single Cell Type RNA - Paneth cells [nTPM]":"37.0","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"21.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.1","Single Cell Type RNA - Spermatocytes [nTPM]":"22.8","Single Cell Type RNA - Spermatogonia [nTPM]":"11.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.1","Single Cell Type RNA - T-cells [nTPM]":"18.5","Single Cell Type RNA - Theca cells [nTPM]":"12.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.7","Single Cell Type RNA - Urothelial cells [nTPM]":"58.7"},{"Gene":"OTOA","Gene synonym":["CT108","DFNB22"],"Ensembl":"ENSG00000155719","Gene description":"Otoancorin","Uniprot":["Q7RTW8"],"Chromosome":"16","Position":"21663968-21761935","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"1.8","testis":"4.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"111.8","Kupffer cells":"60.5","Late spermatids":"18.7","Macrophages":"34.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"dendritic cells":"1.3"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041405"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"51000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041405":"AB_10796344"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"111.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"60.5","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"18.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"34.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"9.4","Single Cell Type RNA - Spermatogonia [nTPM]":"7.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"OTOF","Gene synonym":["DFNB6","DFNB9","FER1L2"],"Ensembl":"ENSG00000115155","Gene description":"Otoferlin","Uniprot":["Q9HC10"],"Chromosome":"2","Position":"26457203-26558756","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Neuropathy","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"bone marrow":"6.4","brain":"23.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"4.0","Skeletal myocytes":"6.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"HDLM-2":"32.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012410"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012410":"AB_1854836"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-5"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"23.1","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"16.3","Tissue RNA - bone marrow [nTPM]":"6.4","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"13.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"32.8","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"23.1","Brain RNA - basal ganglia [nTPM]":"16.3","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"13.1","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"OTOG","Gene synonym":["FLJ46346","mlemp","OTGN"],"Ensembl":"ENSG00000188162","Gene description":"Otogelin","Uniprot":["Q6ZRI0"],"Chromosome":"11","Position":"17547259-17647150","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"1.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"11.9","Late spermatids":"28.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"CACO-2":"8.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"8.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"28.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"OTOGL","Gene synonym":["C12orf64","FLJ90579"],"Ensembl":"ENSG00000165899","Gene description":"Otogelin like","Uniprot":["Q3ZCN5"],"Chromosome":"12","Position":"80099537-80380880","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"1.9","kidney":"5.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"51.2","Oligodendrocyte precursor cells":"42.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.5"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"1.3","U-87 MG":"2.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"4.2"},"Antibody":["HPA040364","HPA053392"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040364":"AB_10795365","HPA053392":"AB_2682135"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"42.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"OVOL2","Gene synonym":["bA504H3.3","CHED","CHED1","HOVO2","ZNF339"],"Ensembl":"ENSG00000125850","Gene description":"Ovo like zinc finger 2","Uniprot":["Q9BRP0"],"Chromosome":"20","Position":"17956979-18059188","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Corneal dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"7.1","stomach 1":"7.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"24.4","Spermatocytes":"37.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"5.6","CACO-2":"4.1","CAPAN-2":"7.3","HaCaT":"5.4","OE19":"10.0","SCLC-21H":"8.3","SK-BR-3":"5.4"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"10.3"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"cerebral cortex":"3.9","hippocampal formation":"3.3"},"Antibody":["HPA038531"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA038531":"AB_10673012"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"1.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.5","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"6.7","Tissue RNA - small intestine [nTPM]":"2.3","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"7.9","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"5.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"4.1","Cell RNA - CAPAN-2 [nTPM]":"7.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"5.4","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"2.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"10.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"2.6","Cell RNA - SCLC-21H [nTPM]":"8.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"5.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"2.8","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"8.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.4","Single Cell Type RNA - Early spermatids [nTPM]":"18.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"10.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"37.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.3","Single Cell Type RNA - Urothelial cells [nTPM]":"15.1"},{"Gene":"P2RX2","Gene synonym":["DFNA41","P2X2"],"Ensembl":"ENSG00000187848","Gene description":"Purinergic receptor P2X 2","Uniprot":["Q9UBL9"],"Chromosome":"12","Position":"132618776-132622388","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Hearing","Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.3","epididymis":"21.8","prostate":"14.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"1.6","Endometrial ciliated cells":"2.6","Fibroblasts":"8.3","Gastric mucus-secreting cells":"1.1","Peritubular cells":"3.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"amygdala":"9.2","cerebral cortex":"11.3","hippocampal formation":"10.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"MCF7":"5.1","T-47d":"11.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"11.3","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"21.8","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"9.3","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"14.1","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"4.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"3.2","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"11.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"11.3","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"P3H2","Gene synonym":["FLJ10718","LEPREL1","MLAT4"],"Ensembl":"ENSG00000090530","Gene description":"Prolyl 3-hydroxylase 2","Uniprot":["Q8IVL5"],"Chromosome":"3","Position":"189956728-190122437","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"80.3","Granulosa cells":"124.1","Microglial cells":"91.8","Theca cells":"74.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"22","RNA blood cell specific nTPM":{"plasmacytoid DC":"28.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"90","RNA blood lineage specific nTPM":{"dendritic cells":"28.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"120.2","HaCaT":"109.9","RPTEC TERT1":"109.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007890","HPA013355","HPA013611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Vesicles","Cytosol"],"Antibody RRID":{"HPA007890":"AB_1852796","HPA013355":"AB_1852798","HPA013611":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"41.6","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"17.0","Tissue RNA - choroid plexus [nTPM]":"1.8","Tissue RNA - colon [nTPM]":"24.0","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"17.6","Tissue RNA - epididymis [nTPM]":"18.5","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"8.8","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"51.3","Tissue RNA - liver [nTPM]":"7.0","Tissue RNA - lung [nTPM]":"28.7","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"16.1","Tissue RNA - pancreas [nTPM]":"3.6","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"37.6","Tissue RNA - rectum [nTPM]":"10.4","Tissue RNA - retina [nTPM]":"19.3","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"26.5","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"17.8","Tissue RNA - small intestine [nTPM]":"6.7","Tissue RNA - smooth muscle [nTPM]":"32.4","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"54.8","Tissue RNA - stomach 1 [nTPM]":"23.9","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"46.9","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"35.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"1.4","Cell RNA - BEWO [nTPM]":"42.1","Cell RNA - BJ [nTPM]":"48.7","Cell RNA - BJ hTERT+ [nTPM]":"19.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"15.0","Cell RNA - CAPAN-2 [nTPM]":"18.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"27.1","Cell RNA - fHDF\/TERT166 [nTPM]":"8.6","Cell RNA - GAMG [nTPM]":"120.2","Cell RNA - HaCaT [nTPM]":"109.9","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"65.3","Cell RNA - HBF TERT88 [nTPM]":"16.3","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"12.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"35.4","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"16.9","Cell RNA - hTCEpi [nTPM]":"21.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.2","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"73.5","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"12.3","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"11.0","Cell RNA - OE19 [nTPM]":"31.3","Cell RNA - PC-3 [nTPM]":"3.7","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"2.8","Cell RNA - RPTEC TERT1 [nTPM]":"109.8","Cell RNA - RT4 [nTPM]":"77.5","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"66.1","Cell RNA - SK-BR-3 [nTPM]":"3.7","Cell RNA - SK-MEL-30 [nTPM]":"29.3","Cell RNA - SuSa [nTPM]":"51.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"24.4","Cell RNA - U-138 MG [nTPM]":"45.9","Cell RNA - U-2 OS [nTPM]":"16.8","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"8.9","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"10.6","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"60.2","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"28.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"5.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"80.3","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.0","Single Cell Type RNA - dendritic cells [nTPM]":"9.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.7","Single Cell Type RNA - Early spermatids [nTPM]":"19.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"55.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"124.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.4","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"60.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"14.9","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"91.8","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"44.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"43.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.6","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.6","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"74.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.9"},{"Gene":"P4HA2","Gene synonym":["C-P4Halpha(II)"],"Ensembl":"ENSG00000072682","Gene description":"Prolyl 4-hydroxylase subunit alpha 2","Uniprot":["O15460"],"Chromosome":"5","Position":"132190147-132295315","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"115.6","Endometrial stromal cells":"96.9","Skeletal myocytes":"109.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"324.2","U-87 MG":"323.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016997","HPA027824","CAB062557"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB062557":"AB_2665641","HPA016997":"AB_2669501","HPA027824":"AB_2672402"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.77e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.12e-4"},"Tissue RNA - adipose tissue [nTPM]":"17.4","Tissue RNA - adrenal gland [nTPM]":"11.7","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"16.1","Tissue RNA - basal ganglia [nTPM]":"12.1","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"12.3","Tissue RNA - cerebellum [nTPM]":"11.4","Tissue RNA - cerebral cortex [nTPM]":"28.4","Tissue RNA - cervix [nTPM]":"29.5","Tissue RNA - choroid plexus [nTPM]":"42.2","Tissue RNA - colon [nTPM]":"28.7","Tissue RNA - duodenum [nTPM]":"22.6","Tissue RNA - endometrium 1 [nTPM]":"31.1","Tissue RNA - epididymis [nTPM]":"76.7","Tissue RNA - esophagus [nTPM]":"19.6","Tissue RNA - fallopian tube [nTPM]":"29.6","Tissue RNA - gallbladder [nTPM]":"19.9","Tissue RNA - heart muscle [nTPM]":"40.6","Tissue RNA - hippocampal formation [nTPM]":"14.4","Tissue RNA - hypothalamus [nTPM]":"17.2","Tissue RNA - kidney [nTPM]":"80.0","Tissue RNA - liver [nTPM]":"10.5","Tissue RNA - lung [nTPM]":"31.5","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"11.4","Tissue RNA - midbrain [nTPM]":"14.3","Tissue RNA - ovary [nTPM]":"8.6","Tissue RNA - pancreas [nTPM]":"70.7","Tissue RNA - parathyroid gland [nTPM]":"10.9","Tissue RNA - pituitary gland [nTPM]":"19.9","Tissue RNA - placenta [nTPM]":"35.1","Tissue RNA - pons [nTPM]":"19.1","Tissue RNA - prostate [nTPM]":"10.8","Tissue RNA - rectum [nTPM]":"32.7","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"32.5","Tissue RNA - seminal vesicle [nTPM]":"17.1","Tissue RNA - skeletal muscle [nTPM]":"13.0","Tissue RNA - skin 1 [nTPM]":"16.7","Tissue RNA - small intestine [nTPM]":"26.8","Tissue RNA - smooth muscle [nTPM]":"52.6","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"8.7","Tissue RNA - stomach 1 [nTPM]":"20.5","Tissue RNA - testis [nTPM]":"9.7","Tissue RNA - thalamus [nTPM]":"16.8","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"20.7","Tissue RNA - tongue [nTPM]":"22.9","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"22.9","Tissue RNA - vagina [nTPM]":"22.3","Tissue RNA - white matter [nTPM]":"12.2","Cell RNA - A-431 [nTPM]":"57.0","Cell RNA - A549 [nTPM]":"34.9","Cell RNA - AF22 [nTPM]":"11.2","Cell RNA - AN3-CA [nTPM]":"57.2","Cell RNA - ASC diff [nTPM]":"149.2","Cell RNA - ASC TERT1 [nTPM]":"173.7","Cell RNA - BEWO [nTPM]":"61.1","Cell RNA - BJ [nTPM]":"261.9","Cell RNA - BJ hTERT+ [nTPM]":"223.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"108.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"265.0","Cell RNA - CACO-2 [nTPM]":"78.9","Cell RNA - CAPAN-2 [nTPM]":"50.3","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"71.8","Cell RNA - fHDF\/TERT166 [nTPM]":"283.3","Cell RNA - GAMG [nTPM]":"120.5","Cell RNA - HaCaT [nTPM]":"70.2","Cell RNA - HAP1 [nTPM]":"33.2","Cell RNA - HBEC3-KT [nTPM]":"136.5","Cell RNA - HBF TERT88 [nTPM]":"172.7","Cell RNA - HDLM-2 [nTPM]":"41.5","Cell RNA - HEK 293 [nTPM]":"11.9","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"48.1","Cell RNA - Hep G2 [nTPM]":"49.0","Cell RNA - HHSteC [nTPM]":"324.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"33.9","Cell RNA - HSkMC [nTPM]":"104.6","Cell RNA - hTCEpi [nTPM]":"193.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"128.8","Cell RNA - hTERT-HME1 [nTPM]":"117.4","Cell RNA - hTERT-RPE1 [nTPM]":"162.7","Cell RNA - HUVEC TERT2 [nTPM]":"59.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"21.2","Cell RNA - Karpas-707 [nTPM]":"3.6","Cell RNA - LHCN-M2 [nTPM]":"134.0","Cell RNA - MCF7 [nTPM]":"23.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"53.7","Cell RNA - PC-3 [nTPM]":"27.2","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"3.6","Cell RNA - RPMI-8226 [nTPM]":"9.8","Cell RNA - RPTEC TERT1 [nTPM]":"31.1","Cell RNA - RT4 [nTPM]":"11.0","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"15.8","Cell RNA - SiHa [nTPM]":"67.7","Cell RNA - SK-BR-3 [nTPM]":"22.3","Cell RNA - SK-MEL-30 [nTPM]":"47.9","Cell RNA - SuSa [nTPM]":"84.1","Cell RNA - T-47d [nTPM]":"28.4","Cell RNA - THP-1 [nTPM]":"3.7","Cell RNA - TIME [nTPM]":"88.9","Cell RNA - U-138 MG [nTPM]":"171.7","Cell RNA - U-2 OS [nTPM]":"63.5","Cell RNA - U-2197 [nTPM]":"51.0","Cell RNA - U-251 MG [nTPM]":"57.1","Cell RNA - U-266\/70 [nTPM]":"24.4","Cell RNA - U-266\/84 [nTPM]":"28.1","Cell RNA - U-698 [nTPM]":"11.8","Cell RNA - U-87 MG [nTPM]":"323.4","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"48.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"12.1","Brain RNA - cerebellum [nTPM]":"11.4","Brain RNA - cerebral cortex [nTPM]":"28.4","Brain RNA - hippocampal formation [nTPM]":"14.4","Brain RNA - hypothalamus [nTPM]":"17.2","Brain RNA - medulla oblongata [nTPM]":"11.4","Brain RNA - midbrain [nTPM]":"14.3","Brain RNA - pons [nTPM]":"19.1","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"16.8","Brain RNA - white matter [nTPM]":"12.2","Single Cell Type RNA - Adipocytes [nTPM]":"13.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.3","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"115.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"36.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"43.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"68.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"96.9","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"70.2","Single Cell Type RNA - Fibroblasts [nTPM]":"61.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.0","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"11.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"7.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.6","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"4.4","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"2.6","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"81.9","Single Cell Type RNA - Paneth cells [nTPM]":"41.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"3.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"44.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"71.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"109.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.6","Single Cell Type RNA - Spermatocytes [nTPM]":"23.0","Single Cell Type RNA - Spermatogonia [nTPM]":"29.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"10.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.8","Single Cell Type RNA - Urothelial cells [nTPM]":"15.3"},{"Gene":"PACS2","Gene synonym":["KIAA0602","PACS1L"],"Ensembl":"ENSG00000179364","Gene description":"Phosphofurin acidic cluster sorting protein 2","Uniprot":["Q86VP3"],"Chromosome":"14","Position":"105300563-105398147","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"136.6","skeletal muscle":"98.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"97.6","Oligodendrocytes":"169.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077892"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA077892":"AB_2686865"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.11e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.95e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.4","Tissue RNA - adrenal gland [nTPM]":"16.1","Tissue RNA - amygdala [nTPM]":"48.4","Tissue RNA - appendix [nTPM]":"10.6","Tissue RNA - basal ganglia [nTPM]":"101.5","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"18.7","Tissue RNA - cerebellum [nTPM]":"104.4","Tissue RNA - cerebral cortex [nTPM]":"61.3","Tissue RNA - cervix [nTPM]":"18.1","Tissue RNA - choroid plexus [nTPM]":"4.7","Tissue RNA - colon [nTPM]":"24.6","Tissue RNA - duodenum [nTPM]":"10.9","Tissue RNA - endometrium 1 [nTPM]":"21.0","Tissue RNA - epididymis [nTPM]":"5.4","Tissue RNA - esophagus [nTPM]":"11.2","Tissue RNA - fallopian tube [nTPM]":"19.0","Tissue RNA - gallbladder [nTPM]":"11.2","Tissue RNA - heart muscle [nTPM]":"23.8","Tissue RNA - hippocampal formation [nTPM]":"43.2","Tissue RNA - hypothalamus [nTPM]":"58.0","Tissue RNA - kidney [nTPM]":"12.4","Tissue RNA - liver [nTPM]":"6.9","Tissue RNA - lung [nTPM]":"16.1","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"136.6","Tissue RNA - midbrain [nTPM]":"110.6","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"28.8","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"21.6","Tissue RNA - placenta [nTPM]":"8.8","Tissue RNA - pons [nTPM]":"119.6","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"12.2","Tissue RNA - salivary gland [nTPM]":"16.3","Tissue RNA - seminal vesicle [nTPM]":"11.5","Tissue RNA - skeletal muscle [nTPM]":"98.5","Tissue RNA - skin 1 [nTPM]":"12.6","Tissue RNA - small intestine [nTPM]":"14.2","Tissue RNA - smooth muscle [nTPM]":"10.0","Tissue RNA - spinal cord [nTPM]":"80.8","Tissue RNA - spleen [nTPM]":"16.0","Tissue RNA - stomach 1 [nTPM]":"17.4","Tissue RNA - testis [nTPM]":"19.8","Tissue RNA - thalamus [nTPM]":"106.1","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"14.1","Tissue RNA - tongue [nTPM]":"46.1","Tissue RNA - tonsil [nTPM]":"5.5","Tissue RNA - urinary bladder [nTPM]":"19.3","Tissue RNA - vagina [nTPM]":"14.1","Tissue RNA - white matter [nTPM]":"126.8","Cell RNA - A-431 [nTPM]":"17.5","Cell RNA - A549 [nTPM]":"23.8","Cell RNA - AF22 [nTPM]":"21.9","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"21.5","Cell RNA - ASC TERT1 [nTPM]":"20.6","Cell RNA - BEWO [nTPM]":"25.9","Cell RNA - BJ [nTPM]":"13.0","Cell RNA - BJ hTERT+ [nTPM]":"15.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.6","Cell RNA - CACO-2 [nTPM]":"10.4","Cell RNA - CAPAN-2 [nTPM]":"32.5","Cell RNA - Daudi [nTPM]":"19.0","Cell RNA - EFO-21 [nTPM]":"21.5","Cell RNA - fHDF\/TERT166 [nTPM]":"20.0","Cell RNA - GAMG [nTPM]":"14.1","Cell RNA - HaCaT [nTPM]":"19.7","Cell RNA - HAP1 [nTPM]":"13.5","Cell RNA - HBEC3-KT [nTPM]":"18.7","Cell RNA - HBF TERT88 [nTPM]":"7.9","Cell RNA - HDLM-2 [nTPM]":"23.7","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"8.7","Cell RNA - HeLa [nTPM]":"10.0","Cell RNA - Hep G2 [nTPM]":"15.6","Cell RNA - HHSteC [nTPM]":"28.1","Cell RNA - HL-60 [nTPM]":"7.1","Cell RNA - HMC-1 [nTPM]":"15.0","Cell RNA - HSkMC [nTPM]":"24.1","Cell RNA - hTCEpi [nTPM]":"17.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.7","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"13.9","Cell RNA - HUVEC TERT2 [nTPM]":"20.1","Cell RNA - JURKAT [nTPM]":"18.9","Cell RNA - K-562 [nTPM]":"5.4","Cell RNA - Karpas-707 [nTPM]":"17.2","Cell RNA - LHCN-M2 [nTPM]":"9.7","Cell RNA - MCF7 [nTPM]":"54.9","Cell RNA - MOLT-4 [nTPM]":"12.1","Cell RNA - NB-4 [nTPM]":"9.5","Cell RNA - NTERA-2 [nTPM]":"8.5","Cell RNA - OE19 [nTPM]":"22.1","Cell RNA - PC-3 [nTPM]":"19.4","Cell RNA - REH [nTPM]":"26.5","Cell RNA - RH-30 [nTPM]":"13.3","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.3","Cell RNA - RT4 [nTPM]":"39.7","Cell RNA - SCLC-21H [nTPM]":"49.0","Cell RNA - SH-SY5Y [nTPM]":"25.8","Cell RNA - SiHa [nTPM]":"12.4","Cell RNA - SK-BR-3 [nTPM]":"11.1","Cell RNA - SK-MEL-30 [nTPM]":"19.4","Cell RNA - SuSa [nTPM]":"13.7","Cell RNA - T-47d [nTPM]":"28.1","Cell RNA - THP-1 [nTPM]":"13.2","Cell RNA - TIME [nTPM]":"30.8","Cell RNA - U-138 MG [nTPM]":"16.2","Cell RNA - U-2 OS [nTPM]":"7.2","Cell RNA - U-2197 [nTPM]":"25.6","Cell RNA - U-251 MG [nTPM]":"13.1","Cell RNA - U-266\/70 [nTPM]":"22.3","Cell RNA - U-266\/84 [nTPM]":"15.6","Cell RNA - U-698 [nTPM]":"7.2","Cell RNA - U-87 MG [nTPM]":"24.6","Cell RNA - U-937 [nTPM]":"12.8","Cell RNA - WM-115 [nTPM]":"16.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"48.4","Brain RNA - basal ganglia [nTPM]":"101.5","Brain RNA - cerebellum [nTPM]":"104.4","Brain RNA - cerebral cortex [nTPM]":"61.3","Brain RNA - hippocampal formation [nTPM]":"43.2","Brain RNA - hypothalamus [nTPM]":"58.0","Brain RNA - medulla oblongata [nTPM]":"136.6","Brain RNA - midbrain [nTPM]":"110.6","Brain RNA - pons [nTPM]":"119.6","Brain RNA - spinal cord [nTPM]":"80.8","Brain RNA - thalamus [nTPM]":"106.1","Brain RNA - white matter [nTPM]":"126.8","Single Cell Type RNA - Adipocytes [nTPM]":"28.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.7","Single Cell Type RNA - Astrocytes [nTPM]":"41.1","Single Cell Type RNA - B-cells [nTPM]":"3.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"30.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.3","Single Cell Type RNA - dendritic cells [nTPM]":"15.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"13.9","Single Cell Type RNA - Early spermatids [nTPM]":"77.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.7","Single Cell Type RNA - Endothelial cells [nTPM]":"21.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"28.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"10.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.6","Single Cell Type RNA - Horizontal cells [nTPM]":"97.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"41.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"23.0","Single Cell Type RNA - Late spermatids [nTPM]":"78.7","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"17.1","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"17.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"169.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.2","Single Cell Type RNA - Paneth cells [nTPM]":"12.6","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"7.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.2","Single Cell Type RNA - Spermatocytes [nTPM]":"18.3","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"8.0","Single Cell Type RNA - Theca cells [nTPM]":"30.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.5","Single Cell Type RNA - Urothelial cells [nTPM]":"8.0"},{"Gene":"PANK2","Gene synonym":["C20orf48","FLJ11729","HARP","HSS","NBIA1","PKAN"],"Ensembl":"ENSG00000125779","Gene description":"Pantothenate kinase 2","Uniprot":["Q9BZ23"],"Chromosome":"20","Position":"3888839-3929887","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Angiogenesis","Coenzyme A biosynthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008440"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008440":"AB_1079559"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.0","Tissue RNA - adrenal gland [nTPM]":"12.3","Tissue RNA - amygdala [nTPM]":"14.5","Tissue RNA - appendix [nTPM]":"16.8","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"20.9","Tissue RNA - breast [nTPM]":"12.2","Tissue RNA - cerebellum [nTPM]":"15.3","Tissue RNA - cerebral cortex [nTPM]":"15.9","Tissue RNA - cervix [nTPM]":"11.9","Tissue RNA - choroid plexus [nTPM]":"14.1","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"8.4","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"11.3","Tissue RNA - esophagus [nTPM]":"20.0","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"12.1","Tissue RNA - heart muscle [nTPM]":"8.7","Tissue RNA - hippocampal formation [nTPM]":"15.5","Tissue RNA - hypothalamus [nTPM]":"13.5","Tissue RNA - kidney [nTPM]":"15.7","Tissue RNA - liver [nTPM]":"18.3","Tissue RNA - lung [nTPM]":"14.1","Tissue RNA - lymph node [nTPM]":"18.5","Tissue RNA - medulla oblongata [nTPM]":"12.7","Tissue RNA - midbrain [nTPM]":"14.1","Tissue RNA - ovary [nTPM]":"12.9","Tissue RNA - pancreas [nTPM]":"10.3","Tissue RNA - parathyroid gland [nTPM]":"10.9","Tissue RNA - pituitary gland [nTPM]":"8.9","Tissue RNA - placenta [nTPM]":"15.3","Tissue RNA - pons [nTPM]":"13.3","Tissue RNA - prostate [nTPM]":"12.0","Tissue RNA - rectum [nTPM]":"14.2","Tissue RNA - retina [nTPM]":"10.3","Tissue RNA - salivary gland [nTPM]":"11.9","Tissue RNA - seminal vesicle [nTPM]":"10.7","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"11.7","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"13.7","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"9.1","Tissue RNA - testis [nTPM]":"25.9","Tissue RNA - thalamus [nTPM]":"13.9","Tissue RNA - thymus [nTPM]":"16.8","Tissue RNA - thyroid gland [nTPM]":"15.4","Tissue RNA - tongue [nTPM]":"11.2","Tissue RNA - tonsil [nTPM]":"22.0","Tissue RNA - urinary bladder [nTPM]":"15.6","Tissue RNA - vagina [nTPM]":"9.9","Tissue RNA - white matter [nTPM]":"12.4","Cell RNA - A-431 [nTPM]":"39.3","Cell RNA - A549 [nTPM]":"29.4","Cell RNA - AF22 [nTPM]":"33.7","Cell RNA - AN3-CA [nTPM]":"18.6","Cell RNA - ASC diff [nTPM]":"39.3","Cell RNA - ASC TERT1 [nTPM]":"32.6","Cell RNA - BEWO [nTPM]":"15.0","Cell RNA - BJ [nTPM]":"25.6","Cell RNA - BJ hTERT+ [nTPM]":"34.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.3","Cell RNA - CACO-2 [nTPM]":"40.8","Cell RNA - CAPAN-2 [nTPM]":"25.4","Cell RNA - Daudi [nTPM]":"34.6","Cell RNA - EFO-21 [nTPM]":"10.6","Cell RNA - fHDF\/TERT166 [nTPM]":"34.9","Cell RNA - GAMG [nTPM]":"70.2","Cell RNA - HaCaT [nTPM]":"34.9","Cell RNA - HAP1 [nTPM]":"34.7","Cell RNA - HBEC3-KT [nTPM]":"57.3","Cell RNA - HBF TERT88 [nTPM]":"49.3","Cell RNA - HDLM-2 [nTPM]":"8.8","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"47.4","Cell RNA - HeLa [nTPM]":"22.7","Cell RNA - Hep G2 [nTPM]":"80.2","Cell RNA - HHSteC [nTPM]":"33.3","Cell RNA - HL-60 [nTPM]":"33.6","Cell RNA - HMC-1 [nTPM]":"15.9","Cell RNA - HSkMC [nTPM]":"28.7","Cell RNA - hTCEpi [nTPM]":"26.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.7","Cell RNA - hTERT-HME1 [nTPM]":"28.7","Cell RNA - hTERT-RPE1 [nTPM]":"17.0","Cell RNA - HUVEC TERT2 [nTPM]":"36.0","Cell RNA - JURKAT [nTPM]":"23.3","Cell RNA - K-562 [nTPM]":"34.7","Cell RNA - Karpas-707 [nTPM]":"30.5","Cell RNA - LHCN-M2 [nTPM]":"42.5","Cell RNA - MCF7 [nTPM]":"11.7","Cell RNA - MOLT-4 [nTPM]":"30.0","Cell RNA - NB-4 [nTPM]":"30.3","Cell RNA - NTERA-2 [nTPM]":"28.8","Cell RNA - OE19 [nTPM]":"22.9","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"20.3","Cell RNA - RH-30 [nTPM]":"46.0","Cell RNA - RPMI-8226 [nTPM]":"22.4","Cell RNA - RPTEC TERT1 [nTPM]":"26.2","Cell RNA - RT4 [nTPM]":"45.7","Cell RNA - SCLC-21H [nTPM]":"36.2","Cell RNA - SH-SY5Y [nTPM]":"16.7","Cell RNA - SiHa [nTPM]":"30.0","Cell RNA - SK-BR-3 [nTPM]":"44.3","Cell RNA - SK-MEL-30 [nTPM]":"78.1","Cell RNA - SuSa [nTPM]":"32.6","Cell RNA - T-47d [nTPM]":"23.6","Cell RNA - THP-1 [nTPM]":"28.1","Cell RNA - TIME [nTPM]":"24.6","Cell RNA - U-138 MG [nTPM]":"47.7","Cell RNA - U-2 OS [nTPM]":"17.8","Cell RNA - U-2197 [nTPM]":"60.7","Cell RNA - U-251 MG [nTPM]":"43.3","Cell RNA - U-266\/70 [nTPM]":"14.0","Cell RNA - U-266\/84 [nTPM]":"50.8","Cell RNA - U-698 [nTPM]":"23.3","Cell RNA - U-87 MG [nTPM]":"15.0","Cell RNA - U-937 [nTPM]":"30.7","Cell RNA - WM-115 [nTPM]":"34.2","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"10.5","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"11.1","Blood RNA - MAIT T-cell [nTPM]":"3.5","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"3.7","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"8.5","Blood RNA - naive B-cell [nTPM]":"4.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"5.9","Blood RNA - NK-cell [nTPM]":"6.8","Blood RNA - non-classical monocyte [nTPM]":"9.4","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"14.5","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"15.3","Brain RNA - cerebral cortex [nTPM]":"15.9","Brain RNA - hippocampal formation [nTPM]":"15.5","Brain RNA - hypothalamus [nTPM]":"13.5","Brain RNA - medulla oblongata [nTPM]":"12.7","Brain RNA - midbrain [nTPM]":"14.1","Brain RNA - pons [nTPM]":"13.3","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"13.9","Brain RNA - white matter [nTPM]":"12.4","Single Cell Type RNA - Adipocytes [nTPM]":"23.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.7","Single Cell Type RNA - Astrocytes [nTPM]":"23.8","Single Cell Type RNA - B-cells [nTPM]":"29.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"41.5","Single Cell Type RNA - Bipolar cells [nTPM]":"22.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"13.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.4","Single Cell Type RNA - dendritic cells [nTPM]":"38.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"19.4","Single Cell Type RNA - Early spermatids [nTPM]":"83.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.6","Single Cell Type RNA - Endothelial cells [nTPM]":"26.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"42.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.0","Single Cell Type RNA - Fibroblasts [nTPM]":"21.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.1","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"20.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"14.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.8","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"52.8","Single Cell Type RNA - Langerhans cells [nTPM]":"37.9","Single Cell Type RNA - Late spermatids [nTPM]":"17.3","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"34.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"55.0","Single Cell Type RNA - Muller glia cells [nTPM]":"14.1","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.9","Single Cell Type RNA - Paneth cells [nTPM]":"12.8","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.1","Single Cell Type RNA - Spermatocytes [nTPM]":"54.6","Single Cell Type RNA - Spermatogonia [nTPM]":"25.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.6","Single Cell Type RNA - T-cells [nTPM]":"31.6","Single Cell Type RNA - Theca cells [nTPM]":"21.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"20.0"},{"Gene":"PARK7","Gene synonym":["DJ-1","DJ1","GATD2"],"Ensembl":"ENSG00000116288","Gene description":"Parkinsonism associated deglycase","Uniprot":["Q99497"],"Chromosome":"1","Position":"7954291-7985505","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","DNA damage","DNA repair","Fertilization","Inflammatory response","Stress response"],"Molecular function":["Chaperone","Hydrolase","Protease","RNA-binding"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004190","CAB005870"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"35000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005870":"AB_444361","HPA004190":"AB_1079566"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Tissue RNA - adipose tissue [nTPM]":"249.4","Tissue RNA - adrenal gland [nTPM]":"373.6","Tissue RNA - amygdala [nTPM]":"283.5","Tissue RNA - appendix [nTPM]":"213.7","Tissue RNA - basal ganglia [nTPM]":"290.0","Tissue RNA - bone marrow [nTPM]":"205.0","Tissue RNA - breast [nTPM]":"235.7","Tissue RNA - cerebellum [nTPM]":"292.9","Tissue RNA - cerebral cortex [nTPM]":"403.4","Tissue RNA - cervix [nTPM]":"201.1","Tissue RNA - choroid plexus [nTPM]":"327.7","Tissue RNA - colon [nTPM]":"252.5","Tissue RNA - duodenum [nTPM]":"145.8","Tissue RNA - endometrium 1 [nTPM]":"212.2","Tissue RNA - epididymis [nTPM]":"278.0","Tissue RNA - esophagus [nTPM]":"161.0","Tissue RNA - fallopian tube [nTPM]":"203.2","Tissue RNA - gallbladder [nTPM]":"162.9","Tissue RNA - heart muscle [nTPM]":"388.0","Tissue RNA - hippocampal formation [nTPM]":"285.5","Tissue RNA - hypothalamus [nTPM]":"296.6","Tissue RNA - kidney [nTPM]":"311.0","Tissue RNA - liver [nTPM]":"397.6","Tissue RNA - lung [nTPM]":"181.6","Tissue RNA - lymph node [nTPM]":"269.2","Tissue RNA - medulla oblongata [nTPM]":"289.6","Tissue RNA - midbrain [nTPM]":"286.0","Tissue RNA - ovary [nTPM]":"234.2","Tissue RNA - pancreas [nTPM]":"308.5","Tissue RNA - parathyroid gland [nTPM]":"387.6","Tissue RNA - pituitary gland [nTPM]":"283.6","Tissue RNA - placenta [nTPM]":"174.1","Tissue RNA - pons [nTPM]":"291.7","Tissue RNA - prostate [nTPM]":"234.9","Tissue RNA - rectum [nTPM]":"194.9","Tissue RNA - retina [nTPM]":"273.8","Tissue RNA - salivary gland [nTPM]":"240.9","Tissue RNA - seminal vesicle [nTPM]":"185.6","Tissue RNA - skeletal muscle [nTPM]":"771.4","Tissue RNA - skin 1 [nTPM]":"127.1","Tissue RNA - small intestine [nTPM]":"170.5","Tissue RNA - smooth muscle [nTPM]":"199.1","Tissue RNA - spinal cord [nTPM]":"295.2","Tissue RNA - spleen [nTPM]":"188.2","Tissue RNA - stomach 1 [nTPM]":"234.2","Tissue RNA - testis [nTPM]":"139.6","Tissue RNA - thalamus [nTPM]":"288.1","Tissue RNA - thymus [nTPM]":"217.9","Tissue RNA - thyroid gland [nTPM]":"286.3","Tissue RNA - tongue [nTPM]":"541.8","Tissue RNA - tonsil [nTPM]":"249.7","Tissue RNA - urinary bladder [nTPM]":"226.5","Tissue RNA - vagina [nTPM]":"171.2","Tissue RNA - white matter [nTPM]":"299.7","Cell RNA - A-431 [nTPM]":"537.0","Cell RNA - A549 [nTPM]":"452.5","Cell RNA - AF22 [nTPM]":"467.1","Cell RNA - AN3-CA [nTPM]":"523.2","Cell RNA - ASC diff [nTPM]":"459.8","Cell RNA - ASC TERT1 [nTPM]":"442.6","Cell RNA - BEWO [nTPM]":"218.4","Cell RNA - BJ [nTPM]":"476.7","Cell RNA - BJ hTERT+ [nTPM]":"434.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"450.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"360.3","Cell RNA - CACO-2 [nTPM]":"419.9","Cell RNA - CAPAN-2 [nTPM]":"549.4","Cell RNA - Daudi [nTPM]":"633.1","Cell RNA - EFO-21 [nTPM]":"534.2","Cell RNA - fHDF\/TERT166 [nTPM]":"505.1","Cell RNA - GAMG [nTPM]":"328.6","Cell RNA - HaCaT [nTPM]":"367.1","Cell RNA - HAP1 [nTPM]":"483.2","Cell RNA - HBEC3-KT [nTPM]":"625.3","Cell RNA - HBF TERT88 [nTPM]":"579.3","Cell RNA - HDLM-2 [nTPM]":"574.5","Cell RNA - HEK 293 [nTPM]":"526.2","Cell RNA - HEL [nTPM]":"683.0","Cell RNA - HeLa [nTPM]":"678.6","Cell RNA - Hep G2 [nTPM]":"674.5","Cell RNA - HHSteC [nTPM]":"403.8","Cell RNA - HL-60 [nTPM]":"662.9","Cell RNA - HMC-1 [nTPM]":"418.6","Cell RNA - HSkMC [nTPM]":"421.3","Cell RNA - hTCEpi [nTPM]":"262.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"459.8","Cell RNA - hTERT-HME1 [nTPM]":"547.4","Cell RNA - hTERT-RPE1 [nTPM]":"359.2","Cell RNA - HUVEC TERT2 [nTPM]":"478.2","Cell RNA - JURKAT [nTPM]":"340.1","Cell RNA - K-562 [nTPM]":"676.8","Cell RNA - Karpas-707 [nTPM]":"471.7","Cell RNA - LHCN-M2 [nTPM]":"633.0","Cell RNA - MCF7 [nTPM]":"485.0","Cell RNA - MOLT-4 [nTPM]":"474.3","Cell RNA - NB-4 [nTPM]":"868.7","Cell RNA - NTERA-2 [nTPM]":"376.1","Cell RNA - OE19 [nTPM]":"653.6","Cell RNA - PC-3 [nTPM]":"465.4","Cell RNA - REH [nTPM]":"366.7","Cell RNA - RH-30 [nTPM]":"598.0","Cell RNA - RPMI-8226 [nTPM]":"888.7","Cell RNA - RPTEC TERT1 [nTPM]":"714.7","Cell RNA - RT4 [nTPM]":"269.7","Cell RNA - SCLC-21H [nTPM]":"527.7","Cell RNA - SH-SY5Y [nTPM]":"447.4","Cell RNA - SiHa [nTPM]":"470.4","Cell RNA - SK-BR-3 [nTPM]":"728.0","Cell RNA - SK-MEL-30 [nTPM]":"798.4","Cell RNA - SuSa [nTPM]":"370.1","Cell RNA - T-47d [nTPM]":"414.9","Cell RNA - THP-1 [nTPM]":"503.7","Cell RNA - TIME [nTPM]":"459.3","Cell RNA - U-138 MG [nTPM]":"412.8","Cell RNA - U-2 OS [nTPM]":"344.6","Cell RNA - U-2197 [nTPM]":"395.5","Cell RNA - U-251 MG [nTPM]":"539.5","Cell RNA - U-266\/70 [nTPM]":"452.8","Cell RNA - U-266\/84 [nTPM]":"788.4","Cell RNA - U-698 [nTPM]":"938.8","Cell RNA - U-87 MG [nTPM]":"551.5","Cell RNA - U-937 [nTPM]":"1002.9","Cell RNA - WM-115 [nTPM]":"606.4","Blood RNA - basophil [nTPM]":"298.4","Blood RNA - classical monocyte [nTPM]":"590.2","Blood RNA - eosinophil [nTPM]":"394.0","Blood RNA - gdT-cell [nTPM]":"484.7","Blood RNA - intermediate monocyte [nTPM]":"553.7","Blood RNA - MAIT T-cell [nTPM]":"459.2","Blood RNA - memory B-cell [nTPM]":"483.6","Blood RNA - memory CD4 T-cell [nTPM]":"478.2","Blood RNA - memory CD8 T-cell [nTPM]":"577.3","Blood RNA - myeloid DC [nTPM]":"717.4","Blood RNA - naive B-cell [nTPM]":"374.6","Blood RNA - naive CD4 T-cell [nTPM]":"406.8","Blood RNA - naive CD8 T-cell [nTPM]":"466.8","Blood RNA - neutrophil [nTPM]":"202.5","Blood RNA - NK-cell [nTPM]":"551.1","Blood RNA - non-classical monocyte [nTPM]":"456.9","Blood RNA - plasmacytoid DC [nTPM]":"1378.2","Blood RNA - T-reg [nTPM]":"874.4","Blood RNA - total PBMC [nTPM]":"1060.8","Brain RNA - amygdala [nTPM]":"283.5","Brain RNA - basal ganglia [nTPM]":"290.0","Brain RNA - cerebellum [nTPM]":"292.9","Brain RNA - cerebral cortex [nTPM]":"403.4","Brain RNA - hippocampal formation [nTPM]":"285.5","Brain RNA - hypothalamus [nTPM]":"296.6","Brain RNA - medulla oblongata [nTPM]":"289.6","Brain RNA - midbrain [nTPM]":"286.0","Brain RNA - pons [nTPM]":"291.7","Brain RNA - spinal cord [nTPM]":"295.2","Brain RNA - thalamus [nTPM]":"288.1","Brain RNA - white matter [nTPM]":"299.7","Single Cell Type RNA - Adipocytes [nTPM]":"243.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"131.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"157.1","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"211.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"208.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"402.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"677.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"200.9","Single Cell Type RNA - Bipolar cells [nTPM]":"196.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"342.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"381.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"453.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"257.4","Single Cell Type RNA - Club cells [nTPM]":"318.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"248.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"553.0","Single Cell Type RNA - dendritic cells [nTPM]":"382.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"131.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"851.0","Single Cell Type RNA - Ductal cells [nTPM]":"504.3","Single Cell Type RNA - Early spermatids [nTPM]":"32.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"272.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"263.9","Single Cell Type RNA - Endothelial cells [nTPM]":"241.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"238.0","Single Cell Type RNA - Erythroid cells [nTPM]":"177.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"478.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"612.1","Single Cell Type RNA - Fibroblasts [nTPM]":"302.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"146.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"195.9","Single Cell Type RNA - granulocytes [nTPM]":"206.5","Single Cell Type RNA - Granulosa cells [nTPM]":"291.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"183.1","Single Cell Type RNA - Hepatocytes [nTPM]":"368.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"435.1","Single Cell Type RNA - Horizontal cells [nTPM]":"186.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"279.6","Single Cell Type RNA - Ionocytes [nTPM]":"484.2","Single Cell Type RNA - Kupffer cells [nTPM]":"204.5","Single Cell Type RNA - Langerhans cells [nTPM]":"304.5","Single Cell Type RNA - Late spermatids [nTPM]":"53.6","Single Cell Type RNA - Leydig cells [nTPM]":"358.2","Single Cell Type RNA - Macrophages [nTPM]":"258.9","Single Cell Type RNA - Melanocytes [nTPM]":"359.3","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"605.4","Single Cell Type RNA - Muller glia cells [nTPM]":"816.4","Single Cell Type RNA - NK-cells [nTPM]":"327.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"378.9","Single Cell Type RNA - Paneth cells [nTPM]":"186.9","Single Cell Type RNA - Peritubular cells [nTPM]":"378.7","Single Cell Type RNA - Plasma cells [nTPM]":"269.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"523.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"227.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"941.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"327.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"235.5","Single Cell Type RNA - Sertoli cells [nTPM]":"276.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"277.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"342.6","Single Cell Type RNA - Spermatocytes [nTPM]":"288.2","Single Cell Type RNA - Spermatogonia [nTPM]":"302.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"220.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"143.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"469.6","Single Cell Type RNA - T-cells [nTPM]":"244.4","Single Cell Type RNA - Theca cells [nTPM]":"535.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"312.2","Single Cell Type RNA - Urothelial cells [nTPM]":"433.1"},{"Gene":"PARS2","Gene synonym":["DKFZp727A071"],"Ensembl":"ENSG00000162396","Gene description":"Prolyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q7L3T8"],"Chromosome":"1","Position":"54756898-54764523","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"9.8","Early spermatids":"11.0","Spermatocytes":"10.5","Spermatogonia":"11.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028308","HPA028314","HPA028518"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoli fibrillar center","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA028308":"AB_2672553","HPA028314":"AB_10603981","HPA028518":"AB_2672653"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.26e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.34e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"4.2","Tissue RNA - liver [nTPM]":"3.4","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"2.0","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"4.7","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"2.0","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"7.2","Cell RNA - AF22 [nTPM]":"4.6","Cell RNA - AN3-CA [nTPM]":"6.0","Cell RNA - ASC diff [nTPM]":"5.5","Cell RNA - ASC TERT1 [nTPM]":"4.6","Cell RNA - BEWO [nTPM]":"10.3","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.6","Cell RNA - CACO-2 [nTPM]":"8.3","Cell RNA - CAPAN-2 [nTPM]":"2.8","Cell RNA - Daudi [nTPM]":"7.7","Cell RNA - EFO-21 [nTPM]":"5.6","Cell RNA - fHDF\/TERT166 [nTPM]":"3.3","Cell RNA - GAMG [nTPM]":"9.3","Cell RNA - HaCaT [nTPM]":"6.9","Cell RNA - HAP1 [nTPM]":"8.3","Cell RNA - HBEC3-KT [nTPM]":"5.8","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"5.0","Cell RNA - HEK 293 [nTPM]":"7.5","Cell RNA - HEL [nTPM]":"7.4","Cell RNA - HeLa [nTPM]":"4.0","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"8.5","Cell RNA - HL-60 [nTPM]":"4.3","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"5.0","Cell RNA - hTCEpi [nTPM]":"8.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.3","Cell RNA - hTERT-HME1 [nTPM]":"7.4","Cell RNA - hTERT-RPE1 [nTPM]":"5.5","Cell RNA - HUVEC TERT2 [nTPM]":"4.8","Cell RNA - JURKAT [nTPM]":"8.4","Cell RNA - K-562 [nTPM]":"13.2","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"4.9","Cell RNA - MCF7 [nTPM]":"4.6","Cell RNA - MOLT-4 [nTPM]":"6.1","Cell RNA - NB-4 [nTPM]":"5.7","Cell RNA - NTERA-2 [nTPM]":"10.6","Cell RNA - OE19 [nTPM]":"8.3","Cell RNA - PC-3 [nTPM]":"9.1","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"9.0","Cell RNA - RPMI-8226 [nTPM]":"9.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.4","Cell RNA - RT4 [nTPM]":"3.2","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"4.8","Cell RNA - SiHa [nTPM]":"5.3","Cell RNA - SK-BR-3 [nTPM]":"6.9","Cell RNA - SK-MEL-30 [nTPM]":"9.7","Cell RNA - SuSa [nTPM]":"8.7","Cell RNA - T-47d [nTPM]":"3.9","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"6.8","Cell RNA - U-251 MG [nTPM]":"4.7","Cell RNA - U-266\/70 [nTPM]":"7.3","Cell RNA - U-266\/84 [nTPM]":"6.6","Cell RNA - U-698 [nTPM]":"3.0","Cell RNA - U-87 MG [nTPM]":"3.6","Cell RNA - U-937 [nTPM]":"5.1","Cell RNA - WM-115 [nTPM]":"2.8","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"5.3","Blood RNA - eosinophil [nTPM]":"4.5","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"7.7","Blood RNA - MAIT T-cell [nTPM]":"5.9","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"5.3","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"7.3","Blood RNA - naive B-cell [nTPM]":"5.5","Blood RNA - naive CD4 T-cell [nTPM]":"7.8","Blood RNA - naive CD8 T-cell [nTPM]":"5.3","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"10.7","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"8.2","Blood RNA - total PBMC [nTPM]":"5.0","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"4.5","Single Cell Type RNA - Early spermatids [nTPM]":"11.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"6.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.5","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.5","Single Cell Type RNA - Spermatogonia [nTPM]":"11.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"PAX6","Gene synonym":["AN","AN1","AN2","D11S812E","WAGR"],"Ensembl":"ENSG00000007372","Gene description":"Paired box 6","Uniprot":["P26367"],"Chromosome":"11","Position":"31784779-31817961","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Disease variant","Peters anomaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"61.6","retina":"68.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Horizontal cells":"264.2","Muller glia cells":"462.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"15.1","AN3-CA":"20.1","HEK 293":"18.0","HeLa":"14.9","hTERT-RPE1":"50.6","U-251 MG":"16.5"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"54.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030775","CAB034143"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB034143":"AB_1127044","HPA030775":"AB_10601243"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"21.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"22.9","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"61.6","Tissue RNA - cerebral cortex [nTPM]":"34.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"16.5","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"23.6","Tissue RNA - hypothalamus [nTPM]":"20.7","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"22.0","Tissue RNA - midbrain [nTPM]":"18.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"9.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"21.7","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"68.9","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"21.4","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"9.4","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"19.6","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"25.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"15.1","Cell RNA - AN3-CA [nTPM]":"20.1","Cell RNA - ASC diff [nTPM]":"4.6","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"5.9","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"3.7","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"6.3","Cell RNA - fHDF\/TERT166 [nTPM]":"2.3","Cell RNA - GAMG [nTPM]":"9.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"18.0","Cell RNA - HEL [nTPM]":"8.9","Cell RNA - HeLa [nTPM]":"14.9","Cell RNA - Hep G2 [nTPM]":"8.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"50.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"5.2","Cell RNA - K-562 [nTPM]":"7.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"3.7","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"10.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"7.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"4.7","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"5.3","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"16.5","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"8.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"21.7","Brain RNA - basal ganglia [nTPM]":"22.9","Brain RNA - cerebellum [nTPM]":"61.6","Brain RNA - cerebral cortex [nTPM]":"34.1","Brain RNA - hippocampal formation [nTPM]":"23.6","Brain RNA - hypothalamus [nTPM]":"20.7","Brain RNA - medulla oblongata [nTPM]":"22.0","Brain RNA - midbrain [nTPM]":"18.1","Brain RNA - pons [nTPM]":"21.7","Brain RNA - spinal cord [nTPM]":"21.4","Brain RNA - thalamus [nTPM]":"19.6","Brain RNA - white matter [nTPM]":"25.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"76.7","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"78.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"74.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"264.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"462.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"21.4","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PCARE","Gene synonym":["C2orf71","FLJ34931","RP54"],"Ensembl":"ENSG00000179270","Gene description":"Photoreceptor cilium actin regulator","Uniprot":["A6NGG8"],"Chromosome":"2","Position":"29060976-29074523","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"retina":"28.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Cardiomyocytes":"2.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"28.5","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PCDH15","Gene synonym":["CDHR15","DFNB23","USH1F"],"Ensembl":"ENSG00000150275","Gene description":"Protocadherin related 15","Uniprot":["Q96QU1"],"Chromosome":"10","Position":"53802771-55627942","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"19.0","brain":"21.2","retina":"61.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"2965.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2 OS":"1.1","U-266\/70":"3.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074437"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074437":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"19.0","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"9.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"10.3","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"16.6","Tissue RNA - hypothalamus [nTPM]":"19.6","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"2.5","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"13.8","Tissue RNA - midbrain [nTPM]":"13.7","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"61.7","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"21.2","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.3","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"9.5","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"10.3","Brain RNA - hippocampal formation [nTPM]":"16.6","Brain RNA - hypothalamus [nTPM]":"19.6","Brain RNA - medulla oblongata [nTPM]":"13.8","Brain RNA - midbrain [nTPM]":"13.7","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"21.2","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"87.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"26.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"216.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2965.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"92.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PCDH19","Gene synonym":["EFMR","EIEE9","KIAA1313"],"Ensembl":"ENSG00000165194","Gene description":"Protocadherin 19","Uniprot":["Q8TAB3"],"Chromosome":"X","Position":"100291644-100410273","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"21.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"29.9","Excitatory neurons":"24.5","Inhibitory neurons":"51.8","Oligodendrocyte precursor cells":"40.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"3.6","ovarian cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"AF22":"18.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027533"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"83000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027533":"AB_10602043"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"7.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"10.7","Tissue RNA - hypothalamus [nTPM]":"12.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"21.5","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"18.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"3.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"2.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"7.6","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"10.7","Brain RNA - hypothalamus [nTPM]":"12.0","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"21.5","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"29.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"2.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"11.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"51.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"3.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PCNA","Gene synonym":[],"Ensembl":"ENSG00000132646","Gene description":"Proliferating cell nuclear antigen","Uniprot":["P12004"],"Chromosome":"20","Position":"5114953-5126626","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","DNA replication","Host-virus interaction"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Dwarfism","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"383.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000148","HPA030521","HPA030522","HPA030523"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000148":"AB_628110","HPA030521":"AB_10600218","HPA030522":"AB_10602096","HPA030523":"AB_10602199"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.86e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"31.2","Tissue RNA - adrenal gland [nTPM]":"47.2","Tissue RNA - amygdala [nTPM]":"23.2","Tissue RNA - appendix [nTPM]":"85.2","Tissue RNA - basal ganglia [nTPM]":"26.0","Tissue RNA - bone marrow [nTPM]":"383.2","Tissue RNA - breast [nTPM]":"51.0","Tissue RNA - cerebellum [nTPM]":"26.8","Tissue RNA - cerebral cortex [nTPM]":"29.7","Tissue RNA - cervix [nTPM]":"41.5","Tissue RNA - choroid plexus [nTPM]":"26.8","Tissue RNA - colon [nTPM]":"89.0","Tissue RNA - duodenum [nTPM]":"70.7","Tissue RNA - endometrium 1 [nTPM]":"38.1","Tissue RNA - epididymis [nTPM]":"30.9","Tissue RNA - esophagus [nTPM]":"81.2","Tissue RNA - fallopian tube [nTPM]":"39.1","Tissue RNA - gallbladder [nTPM]":"34.8","Tissue RNA - heart muscle [nTPM]":"30.6","Tissue RNA - hippocampal formation [nTPM]":"23.0","Tissue RNA - hypothalamus [nTPM]":"24.4","Tissue RNA - kidney [nTPM]":"43.7","Tissue RNA - liver [nTPM]":"55.3","Tissue RNA - lung [nTPM]":"37.5","Tissue RNA - lymph node [nTPM]":"168.8","Tissue RNA - medulla oblongata [nTPM]":"25.1","Tissue RNA - midbrain [nTPM]":"24.0","Tissue RNA - ovary [nTPM]":"37.7","Tissue RNA - pancreas [nTPM]":"32.8","Tissue RNA - parathyroid gland [nTPM]":"42.4","Tissue RNA - pituitary gland [nTPM]":"25.1","Tissue RNA - placenta [nTPM]":"69.8","Tissue RNA - pons [nTPM]":"26.0","Tissue RNA - prostate [nTPM]":"32.2","Tissue RNA - rectum [nTPM]":"93.7","Tissue RNA - retina [nTPM]":"94.1","Tissue RNA - salivary gland [nTPM]":"40.3","Tissue RNA - seminal vesicle [nTPM]":"38.3","Tissue RNA - skeletal muscle [nTPM]":"27.9","Tissue RNA - skin 1 [nTPM]":"62.8","Tissue RNA - small intestine [nTPM]":"72.9","Tissue RNA - smooth muscle [nTPM]":"47.9","Tissue RNA - spinal cord [nTPM]":"26.8","Tissue RNA - spleen [nTPM]":"54.0","Tissue RNA - stomach 1 [nTPM]":"53.9","Tissue RNA - testis [nTPM]":"62.3","Tissue RNA - thalamus [nTPM]":"23.3","Tissue RNA - thymus [nTPM]":"219.9","Tissue RNA - thyroid gland [nTPM]":"42.0","Tissue RNA - tongue [nTPM]":"26.8","Tissue RNA - tonsil [nTPM]":"137.3","Tissue RNA - urinary bladder [nTPM]":"51.0","Tissue RNA - vagina [nTPM]":"42.3","Tissue RNA - white matter [nTPM]":"30.0","Cell RNA - A-431 [nTPM]":"769.1","Cell RNA - A549 [nTPM]":"591.4","Cell RNA - AF22 [nTPM]":"585.0","Cell RNA - AN3-CA [nTPM]":"253.7","Cell RNA - ASC diff [nTPM]":"136.1","Cell RNA - ASC TERT1 [nTPM]":"126.6","Cell RNA - BEWO [nTPM]":"409.5","Cell RNA - BJ [nTPM]":"491.6","Cell RNA - BJ hTERT+ [nTPM]":"288.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"453.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"640.0","Cell RNA - CACO-2 [nTPM]":"465.3","Cell RNA - CAPAN-2 [nTPM]":"594.2","Cell RNA - Daudi [nTPM]":"773.4","Cell RNA - EFO-21 [nTPM]":"155.7","Cell RNA - fHDF\/TERT166 [nTPM]":"177.5","Cell RNA - GAMG [nTPM]":"395.2","Cell RNA - HaCaT [nTPM]":"558.8","Cell RNA - HAP1 [nTPM]":"350.7","Cell RNA - HBEC3-KT [nTPM]":"594.4","Cell RNA - HBF TERT88 [nTPM]":"413.2","Cell RNA - HDLM-2 [nTPM]":"231.7","Cell RNA - HEK 293 [nTPM]":"386.8","Cell RNA - HEL [nTPM]":"543.7","Cell RNA - HeLa [nTPM]":"207.8","Cell RNA - Hep G2 [nTPM]":"1098.3","Cell RNA - HHSteC [nTPM]":"57.8","Cell RNA - HL-60 [nTPM]":"753.7","Cell RNA - HMC-1 [nTPM]":"233.0","Cell RNA - HSkMC [nTPM]":"92.6","Cell RNA - hTCEpi [nTPM]":"138.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"387.2","Cell RNA - hTERT-HME1 [nTPM]":"91.7","Cell RNA - hTERT-RPE1 [nTPM]":"95.3","Cell RNA - HUVEC TERT2 [nTPM]":"263.3","Cell RNA - JURKAT [nTPM]":"503.6","Cell RNA - K-562 [nTPM]":"493.9","Cell RNA - Karpas-707 [nTPM]":"631.2","Cell RNA - LHCN-M2 [nTPM]":"449.7","Cell RNA - MCF7 [nTPM]":"278.3","Cell RNA - MOLT-4 [nTPM]":"1450.6","Cell RNA - NB-4 [nTPM]":"829.3","Cell RNA - NTERA-2 [nTPM]":"439.9","Cell RNA - OE19 [nTPM]":"592.0","Cell RNA - PC-3 [nTPM]":"322.9","Cell RNA - REH [nTPM]":"787.9","Cell RNA - RH-30 [nTPM]":"514.1","Cell RNA - RPMI-8226 [nTPM]":"622.5","Cell RNA - RPTEC TERT1 [nTPM]":"208.5","Cell RNA - RT4 [nTPM]":"441.1","Cell RNA - SCLC-21H [nTPM]":"500.8","Cell RNA - SH-SY5Y [nTPM]":"339.4","Cell RNA - SiHa [nTPM]":"345.1","Cell RNA - SK-BR-3 [nTPM]":"524.6","Cell RNA - SK-MEL-30 [nTPM]":"351.9","Cell RNA - SuSa [nTPM]":"213.9","Cell RNA - T-47d [nTPM]":"371.2","Cell RNA - THP-1 [nTPM]":"378.0","Cell RNA - TIME [nTPM]":"177.2","Cell RNA - U-138 MG [nTPM]":"324.3","Cell RNA - U-2 OS [nTPM]":"373.3","Cell RNA - U-2197 [nTPM]":"461.5","Cell RNA - U-251 MG [nTPM]":"572.0","Cell RNA - U-266\/70 [nTPM]":"317.2","Cell RNA - U-266\/84 [nTPM]":"981.6","Cell RNA - U-698 [nTPM]":"1313.9","Cell RNA - U-87 MG [nTPM]":"145.9","Cell RNA - U-937 [nTPM]":"707.4","Cell RNA - WM-115 [nTPM]":"426.2","Blood RNA - basophil [nTPM]":"5.0","Blood RNA - classical monocyte [nTPM]":"23.2","Blood RNA - eosinophil [nTPM]":"18.5","Blood RNA - gdT-cell [nTPM]":"36.5","Blood RNA - intermediate monocyte [nTPM]":"23.3","Blood RNA - MAIT T-cell [nTPM]":"45.7","Blood RNA - memory B-cell [nTPM]":"33.5","Blood RNA - memory CD4 T-cell [nTPM]":"45.7","Blood RNA - memory CD8 T-cell [nTPM]":"37.1","Blood RNA - myeloid DC [nTPM]":"32.6","Blood RNA - naive B-cell [nTPM]":"29.2","Blood RNA - naive CD4 T-cell [nTPM]":"41.6","Blood RNA - naive CD8 T-cell [nTPM]":"37.3","Blood RNA - neutrophil [nTPM]":"7.7","Blood RNA - NK-cell [nTPM]":"43.6","Blood RNA - non-classical monocyte [nTPM]":"24.7","Blood RNA - plasmacytoid DC [nTPM]":"29.9","Blood RNA - T-reg [nTPM]":"48.1","Blood RNA - total PBMC [nTPM]":"36.7","Brain RNA - amygdala [nTPM]":"23.2","Brain RNA - basal ganglia [nTPM]":"26.0","Brain RNA - cerebellum [nTPM]":"26.8","Brain RNA - cerebral cortex [nTPM]":"29.7","Brain RNA - hippocampal formation [nTPM]":"23.0","Brain RNA - hypothalamus [nTPM]":"24.4","Brain RNA - medulla oblongata [nTPM]":"25.1","Brain RNA - midbrain [nTPM]":"24.0","Brain RNA - pons [nTPM]":"26.0","Brain RNA - spinal cord [nTPM]":"26.8","Brain RNA - thalamus [nTPM]":"23.3","Brain RNA - white matter [nTPM]":"30.0","Single Cell Type RNA - Adipocytes [nTPM]":"32.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"40.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"67.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"121.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"42.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"60.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"171.5","Single Cell Type RNA - dendritic cells [nTPM]":"44.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"51.6","Single Cell Type RNA - Early spermatids [nTPM]":"176.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.4","Single Cell Type RNA - Endothelial cells [nTPM]":"34.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.9","Single Cell Type RNA - Erythroid cells [nTPM]":"189.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"39.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"175.6","Single Cell Type RNA - Fibroblasts [nTPM]":"38.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.7","Single Cell Type RNA - granulocytes [nTPM]":"22.7","Single Cell Type RNA - Granulosa cells [nTPM]":"53.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"27.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"96.7","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"53.9","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"24.2","Single Cell Type RNA - Langerhans cells [nTPM]":"33.4","Single Cell Type RNA - Late spermatids [nTPM]":"109.1","Single Cell Type RNA - Leydig cells [nTPM]":"36.1","Single Cell Type RNA - Macrophages [nTPM]":"32.7","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"47.6","Single Cell Type RNA - Muller glia cells [nTPM]":"74.0","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.3","Single Cell Type RNA - Paneth cells [nTPM]":"20.3","Single Cell Type RNA - Peritubular cells [nTPM]":"40.3","Single Cell Type RNA - Plasma cells [nTPM]":"56.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"44.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"97.1","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.1","Single Cell Type RNA - Spermatocytes [nTPM]":"149.1","Single Cell Type RNA - Spermatogonia [nTPM]":"101.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"65.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"49.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.4","Single Cell Type RNA - T-cells [nTPM]":"48.6","Single Cell Type RNA - Theca cells [nTPM]":"29.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"84.5","Single Cell Type RNA - Urothelial cells [nTPM]":"40.4"},{"Gene":"PCYT2","Gene synonym":["ET"],"Ensembl":"ENSG00000185813","Gene description":"Phosphate cytidylyltransferase 2, ethanolamine","Uniprot":["Q99447"],"Chromosome":"17","Position":"81900958-81911432","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"165.7","testis":"261.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"763.2","Late spermatids":"2829.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"218.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023033","HPA023034"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"84000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA023033":"AB_1855094","HPA023034":"AB_1855095"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.29e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.7","Tissue RNA - adrenal gland [nTPM]":"16.8","Tissue RNA - amygdala [nTPM]":"40.0","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"40.1","Tissue RNA - bone marrow [nTPM]":"12.1","Tissue RNA - breast [nTPM]":"25.2","Tissue RNA - cerebellum [nTPM]":"44.4","Tissue RNA - cerebral cortex [nTPM]":"45.8","Tissue RNA - cervix [nTPM]":"14.9","Tissue RNA - choroid plexus [nTPM]":"30.4","Tissue RNA - colon [nTPM]":"25.5","Tissue RNA - duodenum [nTPM]":"63.9","Tissue RNA - endometrium 1 [nTPM]":"18.0","Tissue RNA - epididymis [nTPM]":"13.5","Tissue RNA - esophagus [nTPM]":"26.3","Tissue RNA - fallopian tube [nTPM]":"23.9","Tissue RNA - gallbladder [nTPM]":"9.9","Tissue RNA - heart muscle [nTPM]":"47.7","Tissue RNA - hippocampal formation [nTPM]":"41.2","Tissue RNA - hypothalamus [nTPM]":"37.7","Tissue RNA - kidney [nTPM]":"44.0","Tissue RNA - liver [nTPM]":"165.7","Tissue RNA - lung [nTPM]":"21.3","Tissue RNA - lymph node [nTPM]":"12.0","Tissue RNA - medulla oblongata [nTPM]":"47.0","Tissue RNA - midbrain [nTPM]":"43.0","Tissue RNA - ovary [nTPM]":"20.9","Tissue RNA - pancreas [nTPM]":"25.3","Tissue RNA - parathyroid gland [nTPM]":"20.2","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"12.0","Tissue RNA - pons [nTPM]":"47.3","Tissue RNA - prostate [nTPM]":"24.2","Tissue RNA - rectum [nTPM]":"16.7","Tissue RNA - retina [nTPM]":"8.6","Tissue RNA - salivary gland [nTPM]":"22.3","Tissue RNA - seminal vesicle [nTPM]":"12.1","Tissue RNA - skeletal muscle [nTPM]":"33.5","Tissue RNA - skin 1 [nTPM]":"16.3","Tissue RNA - small intestine [nTPM]":"43.0","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"41.3","Tissue RNA - spleen [nTPM]":"12.8","Tissue RNA - stomach 1 [nTPM]":"35.4","Tissue RNA - testis [nTPM]":"261.7","Tissue RNA - thalamus [nTPM]":"41.0","Tissue RNA - thymus [nTPM]":"13.5","Tissue RNA - thyroid gland [nTPM]":"16.2","Tissue RNA - tongue [nTPM]":"29.3","Tissue RNA - tonsil [nTPM]":"11.9","Tissue RNA - urinary bladder [nTPM]":"21.2","Tissue RNA - vagina [nTPM]":"15.1","Tissue RNA - white matter [nTPM]":"44.0","Cell RNA - A-431 [nTPM]":"42.6","Cell RNA - A549 [nTPM]":"23.9","Cell RNA - AF22 [nTPM]":"18.8","Cell RNA - AN3-CA [nTPM]":"53.1","Cell RNA - ASC diff [nTPM]":"91.8","Cell RNA - ASC TERT1 [nTPM]":"48.0","Cell RNA - BEWO [nTPM]":"27.9","Cell RNA - BJ [nTPM]":"29.9","Cell RNA - BJ hTERT+ [nTPM]":"63.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.0","Cell RNA - CACO-2 [nTPM]":"94.0","Cell RNA - CAPAN-2 [nTPM]":"43.0","Cell RNA - Daudi [nTPM]":"14.8","Cell RNA - EFO-21 [nTPM]":"16.0","Cell RNA - fHDF\/TERT166 [nTPM]":"31.1","Cell RNA - GAMG [nTPM]":"75.3","Cell RNA - HaCaT [nTPM]":"34.5","Cell RNA - HAP1 [nTPM]":"28.6","Cell RNA - HBEC3-KT [nTPM]":"55.1","Cell RNA - HBF TERT88 [nTPM]":"23.5","Cell RNA - HDLM-2 [nTPM]":"4.5","Cell RNA - HEK 293 [nTPM]":"24.3","Cell RNA - HEL [nTPM]":"32.1","Cell RNA - HeLa [nTPM]":"33.3","Cell RNA - Hep G2 [nTPM]":"218.2","Cell RNA - HHSteC [nTPM]":"97.8","Cell RNA - HL-60 [nTPM]":"32.5","Cell RNA - HMC-1 [nTPM]":"26.0","Cell RNA - HSkMC [nTPM]":"39.8","Cell RNA - hTCEpi [nTPM]":"31.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.8","Cell RNA - hTERT-HME1 [nTPM]":"28.4","Cell RNA - hTERT-RPE1 [nTPM]":"14.5","Cell RNA - HUVEC TERT2 [nTPM]":"38.6","Cell RNA - JURKAT [nTPM]":"44.0","Cell RNA - K-562 [nTPM]":"60.6","Cell RNA - Karpas-707 [nTPM]":"29.6","Cell RNA - LHCN-M2 [nTPM]":"30.8","Cell RNA - MCF7 [nTPM]":"35.7","Cell RNA - MOLT-4 [nTPM]":"39.3","Cell RNA - NB-4 [nTPM]":"40.1","Cell RNA - NTERA-2 [nTPM]":"15.1","Cell RNA - OE19 [nTPM]":"147.2","Cell RNA - PC-3 [nTPM]":"25.9","Cell RNA - REH [nTPM]":"25.4","Cell RNA - RH-30 [nTPM]":"20.2","Cell RNA - RPMI-8226 [nTPM]":"52.4","Cell RNA - RPTEC TERT1 [nTPM]":"49.2","Cell RNA - RT4 [nTPM]":"78.8","Cell RNA - SCLC-21H [nTPM]":"23.9","Cell RNA - SH-SY5Y [nTPM]":"21.9","Cell RNA - SiHa [nTPM]":"22.4","Cell RNA - SK-BR-3 [nTPM]":"121.7","Cell RNA - SK-MEL-30 [nTPM]":"29.0","Cell RNA - SuSa [nTPM]":"36.5","Cell RNA - T-47d [nTPM]":"33.9","Cell RNA - THP-1 [nTPM]":"75.3","Cell RNA - TIME [nTPM]":"26.1","Cell RNA - U-138 MG [nTPM]":"30.0","Cell RNA - U-2 OS [nTPM]":"19.7","Cell RNA - U-2197 [nTPM]":"22.9","Cell RNA - U-251 MG [nTPM]":"25.0","Cell RNA - U-266\/70 [nTPM]":"19.3","Cell RNA - U-266\/84 [nTPM]":"9.1","Cell RNA - U-698 [nTPM]":"15.3","Cell RNA - U-87 MG [nTPM]":"31.2","Cell RNA - U-937 [nTPM]":"42.8","Cell RNA - WM-115 [nTPM]":"29.9","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"4.6","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"4.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.7","Blood RNA - myeloid DC [nTPM]":"4.5","Blood RNA - naive B-cell [nTPM]":"5.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"4.6","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"3.6","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"40.0","Brain RNA - basal ganglia [nTPM]":"40.1","Brain RNA - cerebellum [nTPM]":"44.4","Brain RNA - cerebral cortex [nTPM]":"45.8","Brain RNA - hippocampal formation [nTPM]":"41.2","Brain RNA - hypothalamus [nTPM]":"37.7","Brain RNA - medulla oblongata [nTPM]":"47.0","Brain RNA - midbrain [nTPM]":"43.0","Brain RNA - pons [nTPM]":"47.3","Brain RNA - spinal cord [nTPM]":"41.3","Brain RNA - thalamus [nTPM]":"41.0","Brain RNA - white matter [nTPM]":"44.0","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.3","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"11.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"12.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"62.9","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"73.1","Single Cell Type RNA - dendritic cells [nTPM]":"21.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"119.3","Single Cell Type RNA - Ductal cells [nTPM]":"19.5","Single Cell Type RNA - Early spermatids [nTPM]":"763.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.5","Single Cell Type RNA - Endothelial cells [nTPM]":"8.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.9","Single Cell Type RNA - Erythroid cells [nTPM]":"47.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.7","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.8","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"39.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"166.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.1","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"11.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.3","Single Cell Type RNA - Late spermatids [nTPM]":"2829.0","Single Cell Type RNA - Leydig cells [nTPM]":"27.7","Single Cell Type RNA - Macrophages [nTPM]":"8.1","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"14.7","Single Cell Type RNA - Muller glia cells [nTPM]":"26.7","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.8","Single Cell Type RNA - Paneth cells [nTPM]":"18.8","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"144.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"130.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.5","Single Cell Type RNA - Spermatocytes [nTPM]":"253.1","Single Cell Type RNA - Spermatogonia [nTPM]":"18.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.8","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"34.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"48.7","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"PDCD1","Gene synonym":["CD279","hSLE1","PD-1","PD1","SLEB2"],"Ensembl":"ENSG00000188389","Gene description":"Programmed cell death 1","Uniprot":["Q15116"],"Chromosome":"2","Position":"241849884-241858894","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Apoptosis","Immunity"],"Molecular function":null,"Disease involvement":["FDA approved drug targets","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"6.7","lymphoid tissue":"16.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Plasma cells":"9.5","T-cells":"34.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"1.4"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"4.4","MAIT T-cell":"4.8","memory CD4 T-cell":"8.7","memory CD8 T-cell":"12.4","T-reg":"4.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"55","RNA blood lineage specific nTPM":{"T-cells":"12.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"JURKAT":"1.5","MOLT-4":"2.4","RPMI-8226":"6.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035981","CAB038418","CAB076386"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB038418":"AB_1160824","CAB076386":"AB_881954","HPA035981":"AB_10669664"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.44e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.48e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"3.2","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"16.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"1.8","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"4.0","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.5","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"2.4","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"6.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"4.8","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"8.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"4.3","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"34.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PDE10A","Gene synonym":[],"Ensembl":"ENSG00000112541","Gene description":"Phosphodiesterase 10A","Uniprot":["Q9Y233"],"Chromosome":"6","Position":"165327287-165988078","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Hydrolase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"67.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"204.7","Inhibitory neurons":"209.6","Microglial cells":"89.0","Oligodendrocyte precursor cells":"48.7","Oligodendrocytes":"51.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"basal ganglia":"67.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"9.0","LHCN-M2":"12.5","RT4":"6.9","SH-SY5Y":"8.1","TIME":"11.3","U-2 OS":"7.0"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"basal ganglia":"350.1"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"basal ganglia":"194.1"},"Antibody":["CAB045998","HPA047200"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB045998":"AB_2162589","HPA047200":"AB_2679981"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.44e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.6","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"67.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"3.6","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"9.6","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"3.2","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.4","Cell RNA - AF22 [nTPM]":"5.5","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"6.3","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.8","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"3.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"9.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"5.5","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"12.5","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"4.7","Cell RNA - REH [nTPM]":"1.5","Cell RNA - RH-30 [nTPM]":"5.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"6.9","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"8.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"11.3","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"7.0","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"67.2","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"9.6","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"13.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"7.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"14.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"204.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"209.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"14.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"89.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"51.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.9"},{"Gene":"PDE1C","Gene synonym":["Hcam3"],"Ensembl":"ENSG00000154678","Gene description":"Phosphodiesterase 1C","Uniprot":["Q14123"],"Chromosome":"7","Position":"31751179-32428131","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Hydrolase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"68.9","heart muscle":"58.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocytes":"1071.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"44.4","fHDF\/TERT166":"148.3","hTERT-RPE1":"44.9","U-251 MG":"77.9","WM-115":"105.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052375"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA052375":"AB_2681802"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.4","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"19.2","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"43.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"4.3","Tissue RNA - cerebellum [nTPM]":"21.4","Tissue RNA - cerebral cortex [nTPM]":"39.9","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.0","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"2.4","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"10.5","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"58.5","Tissue RNA - hippocampal formation [nTPM]":"18.9","Tissue RNA - hypothalamus [nTPM]":"24.2","Tissue RNA - kidney [nTPM]":"4.2","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"29.4","Tissue RNA - midbrain [nTPM]":"27.9","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"27.7","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"3.3","Tissue RNA - smooth muscle [nTPM]":"5.0","Tissue RNA - spinal cord [nTPM]":"16.4","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"4.0","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"28.6","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"4.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"68.9","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"5.8","Cell RNA - AF22 [nTPM]":"15.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"44.4","Cell RNA - BJ hTERT+ [nTPM]":"18.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"148.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"27.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.3","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"31.9","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.3","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"44.9","Cell RNA - HUVEC TERT2 [nTPM]":"7.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"13.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"22.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"6.8","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"22.8","Cell RNA - U-2 OS [nTPM]":"8.6","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"77.9","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.4","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"105.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"19.2","Brain RNA - basal ganglia [nTPM]":"43.0","Brain RNA - cerebellum [nTPM]":"21.4","Brain RNA - cerebral cortex [nTPM]":"39.9","Brain RNA - hippocampal formation [nTPM]":"18.9","Brain RNA - hypothalamus [nTPM]":"24.2","Brain RNA - medulla oblongata [nTPM]":"29.4","Brain RNA - midbrain [nTPM]":"27.9","Brain RNA - pons [nTPM]":"27.7","Brain RNA - spinal cord [nTPM]":"16.4","Brain RNA - thalamus [nTPM]":"28.6","Brain RNA - white matter [nTPM]":"68.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"69.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"136.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.8","Single Cell Type RNA - Early spermatids [nTPM]":"53.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"169.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.2","Single Cell Type RNA - Late spermatids [nTPM]":"50.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"196.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1071.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PDE6A","Gene synonym":["PDEA","RP43"],"Ensembl":"ENSG00000132915","Gene description":"Phosphodiesterase 6A","Uniprot":["P16499"],"Chromosome":"5","Position":"149857953-149944793","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"68","RNA tissue specific nTPM":{"retina":"1119.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"2946.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"CACO-2":"2.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016970","HPA074677"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016970":"AB_1855125","HPA074677":"AB_2732264"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"1.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"16.3","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"1119.5","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.5","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"150.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"244.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"18.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"11.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"75.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.4","Single Cell Type RNA - Muller glia cells [nTPM]":"263.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2946.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"2.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"PDE6B","Gene synonym":["CSNB3","CSNBAD2","PDEB","rd1","RP40"],"Ensembl":"ENSG00000133256","Gene description":"Phosphodiesterase 6B","Uniprot":["P35913"],"Chromosome":"4","Position":"625573-670782","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":["Congenital stationary night blindness","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"retina":"385.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"460.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"11.5","JURKAT":"17.3","MOLT-4":"31.3","REH":"16.8","SCLC-21H":"20.2","SH-SY5Y":"11.9","U-266\/84":"24.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054148","HPA059929"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA054148":"AB_2682401","HPA059929":"AB_2684166"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.34e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"13.5","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"25.7","Tissue RNA - bone marrow [nTPM]":"8.4","Tissue RNA - breast [nTPM]":"4.1","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"22.3","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"1.7","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"2.7","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"10.2","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"5.9","Tissue RNA - hippocampal formation [nTPM]":"11.2","Tissue RNA - hypothalamus [nTPM]":"22.6","Tissue RNA - kidney [nTPM]":"4.9","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"14.3","Tissue RNA - medulla oblongata [nTPM]":"22.8","Tissue RNA - midbrain [nTPM]":"19.9","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"8.2","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"25.5","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"385.0","Tissue RNA - salivary gland [nTPM]":"3.8","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"3.0","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"9.3","Tissue RNA - spleen [nTPM]":"10.1","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"4.4","Tissue RNA - thalamus [nTPM]":"24.1","Tissue RNA - thymus [nTPM]":"12.2","Tissue RNA - thyroid gland [nTPM]":"12.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"9.3","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"39.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"11.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"2.5","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"5.8","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"1.1","Cell RNA - JURKAT [nTPM]":"17.3","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"31.3","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"9.4","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"16.8","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"20.2","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"4.2","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"7.7","Cell RNA - U-266\/84 [nTPM]":"24.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"16.8","Blood RNA - classical monocyte [nTPM]":"5.4","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"14.0","Blood RNA - intermediate monocyte [nTPM]":"7.7","Blood RNA - MAIT T-cell [nTPM]":"12.6","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"9.3","Blood RNA - memory CD8 T-cell [nTPM]":"9.8","Blood RNA - myeloid DC [nTPM]":"8.5","Blood RNA - naive B-cell [nTPM]":"21.4","Blood RNA - naive CD4 T-cell [nTPM]":"14.6","Blood RNA - naive CD8 T-cell [nTPM]":"15.8","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"14.4","Blood RNA - non-classical monocyte [nTPM]":"8.1","Blood RNA - plasmacytoid DC [nTPM]":"18.2","Blood RNA - T-reg [nTPM]":"15.5","Blood RNA - total PBMC [nTPM]":"9.4","Brain RNA - amygdala [nTPM]":"13.5","Brain RNA - basal ganglia [nTPM]":"25.7","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"22.3","Brain RNA - hippocampal formation [nTPM]":"11.2","Brain RNA - hypothalamus [nTPM]":"22.6","Brain RNA - medulla oblongata [nTPM]":"22.8","Brain RNA - midbrain [nTPM]":"19.9","Brain RNA - pons [nTPM]":"25.5","Brain RNA - spinal cord [nTPM]":"9.3","Brain RNA - thalamus [nTPM]":"24.1","Brain RNA - white matter [nTPM]":"39.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"6.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"20.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"83.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"5.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.3","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.1","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"6.2","Single Cell Type RNA - Muller glia cells [nTPM]":"31.1","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"7.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"460.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"4.3","Single Cell Type RNA - Spermatogonia [nTPM]":"11.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"5.9","Single Cell Type RNA - Theca cells [nTPM]":"3.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"PDE6C","Gene synonym":["ACHM5","COD4","PDEA2"],"Ensembl":"ENSG00000095464","Gene description":"Phosphodiesterase 6C","Uniprot":["P51160"],"Chromosome":"10","Position":"93612537-93666010","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"26","RNA tissue specific nTPM":{"retina":"23.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"56.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"23.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PDE6G","Gene synonym":["PDEG","RP57"],"Ensembl":"ENSG00000185527","Gene description":"Phosphodiesterase 6G","Uniprot":["P18545"],"Chromosome":"17","Position":"81650459-81663112","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"99","RNA tissue specific nTPM":{"retina":"2050.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"4448.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"10.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"127.0","NK-cell":"220.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"127.0","NK-cells":"220.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"5.2","NB-4":"5.8","NTERA-2":"8.9","REH":"11.9","SuSa":"6.2"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hippocampal formation":"4.7"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045118"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA045118":"AB_2732517"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"7.8","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"2.1","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"3.0","Tissue RNA - lymph node [nTPM]":"20.6","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"12.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"2050.3","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"19.9","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"8.3","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"2.8","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"5.8","Cell RNA - NTERA-2 [nTPM]":"8.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"11.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"3.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"127.0","Blood RNA - classical monocyte [nTPM]":"18.1","Blood RNA - eosinophil [nTPM]":"30.5","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"26.2","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.3","Blood RNA - myeloid DC [nTPM]":"28.9","Blood RNA - naive B-cell [nTPM]":"5.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"7.4","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"220.2","Blood RNA - non-classical monocyte [nTPM]":"15.5","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"13.5","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"422.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"517.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"4.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"27.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"23.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.6","Single Cell Type RNA - Horizontal cells [nTPM]":"262.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.8","Single Cell Type RNA - Langerhans cells [nTPM]":"8.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"4.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"13.3","Single Cell Type RNA - Muller glia cells [nTPM]":"709.0","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4448.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PDE6H","Gene synonym":[],"Ensembl":"ENSG00000139053","Gene description":"Phosphodiesterase 6H","Uniprot":["Q13956"],"Chromosome":"12","Position":"14973042-14981865","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"226","RNA tissue specific nTPM":{"retina":"911.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"831.9","Rod photoreceptor cells":"218.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"1.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045118"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA045118":"AB_2732517"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"911.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"62.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"831.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"81.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"218.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PDE8B","Gene synonym":[],"Ensembl":"ENSG00000113231","Gene description":"Phosphodiesterase 8B","Uniprot":["O95263"],"Chromosome":"5","Position":"77210449-77428256","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cushing syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"124.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"64.9","Excitatory neurons":"183.1","Horizontal cells":"69.0","Inhibitory neurons":"276.5","Muller glia cells":"86.5","Oligodendrocyte precursor cells":"190.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"thyroid cancer":"35.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"13.6","HeLa":"34.8","SK-BR-3":"11.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036911","HPA036912"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036911":"AB_2675378","HPA036912":"AB_10670377"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.9","Tissue RNA - adrenal gland [nTPM]":"4.8","Tissue RNA - amygdala [nTPM]":"24.2","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"28.6","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"14.0","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"24.6","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"5.6","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"26.4","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"28.7","Tissue RNA - gallbladder [nTPM]":"4.3","Tissue RNA - heart muscle [nTPM]":"23.7","Tissue RNA - hippocampal formation [nTPM]":"25.5","Tissue RNA - hypothalamus [nTPM]":"32.5","Tissue RNA - kidney [nTPM]":"15.6","Tissue RNA - liver [nTPM]":"2.3","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"20.5","Tissue RNA - midbrain [nTPM]":"15.9","Tissue RNA - ovary [nTPM]":"4.2","Tissue RNA - pancreas [nTPM]":"7.9","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"12.5","Tissue RNA - placenta [nTPM]":"23.8","Tissue RNA - pons [nTPM]":"18.8","Tissue RNA - prostate [nTPM]":"19.0","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"22.5","Tissue RNA - salivary gland [nTPM]":"10.5","Tissue RNA - seminal vesicle [nTPM]":"11.9","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"3.3","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"36.7","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"124.7","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"17.2","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"13.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"34.8","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"2.3","Cell RNA - SK-BR-3 [nTPM]":"11.1","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"1.8","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"24.2","Brain RNA - basal ganglia [nTPM]":"28.6","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"24.6","Brain RNA - hippocampal formation [nTPM]":"25.5","Brain RNA - hypothalamus [nTPM]":"32.5","Brain RNA - medulla oblongata [nTPM]":"20.5","Brain RNA - midbrain [nTPM]":"15.9","Brain RNA - pons [nTPM]":"18.8","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"36.7","Brain RNA - white matter [nTPM]":"17.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"64.9","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.3","Single Cell Type RNA - Early spermatids [nTPM]":"6.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"183.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"69.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"276.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"86.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"190.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"45.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"8.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"4.2"},{"Gene":"PDGFB","Gene synonym":["SIS","SSV"],"Ensembl":"ENSG00000100311","Gene description":"Platelet derived growth factor subunit B","Uniprot":["P01127"],"Chromosome":"22","Position":"39223359-39244982","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Developmental protein","Growth factor","Mitogen"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"75.0","Endothelial cells":"60.6","Langerhans cells":"44.3","Macrophages":"25.5","Pancreatic endocrine cells":"54.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"10.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"T-cells":"10.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"33.8","EFO-21":"69.2","HUVEC TERT2":"52.6","SK-BR-3":"53.5","TIME":"68.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011604","HPA011972","CAB018341"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":4390000,"Blood concentration - Conc. blood MS [pg\/L]":"950000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB011604":"AB_2162180","CAB018341":"AB_2162187","HPA011972":"AB_1855134"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.67e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"32.6","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"14.7","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"24.0","Tissue RNA - cerebellum [nTPM]":"10.3","Tissue RNA - cerebral cortex [nTPM]":"22.2","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"4.8","Tissue RNA - colon [nTPM]":"20.6","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"8.9","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"6.2","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"11.7","Tissue RNA - heart muscle [nTPM]":"31.2","Tissue RNA - hippocampal formation [nTPM]":"12.0","Tissue RNA - hypothalamus [nTPM]":"9.8","Tissue RNA - kidney [nTPM]":"17.0","Tissue RNA - liver [nTPM]":"3.7","Tissue RNA - lung [nTPM]":"28.1","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"12.4","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"8.8","Tissue RNA - parathyroid gland [nTPM]":"8.9","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"40.2","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"7.6","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"10.6","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"18.7","Tissue RNA - skin 1 [nTPM]":"10.3","Tissue RNA - small intestine [nTPM]":"9.1","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"10.6","Tissue RNA - spleen [nTPM]":"6.6","Tissue RNA - stomach 1 [nTPM]":"7.9","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"16.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"16.1","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"9.4","Cell RNA - A-431 [nTPM]":"33.8","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"8.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"9.9","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"13.0","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"69.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.1","Cell RNA - HaCaT [nTPM]":"12.4","Cell RNA - HAP1 [nTPM]":"0.5","Cell RNA - HBEC3-KT [nTPM]":"2.8","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"4.8","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"18.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"52.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"6.1","Cell RNA - LHCN-M2 [nTPM]":"1.9","Cell RNA - MCF7 [nTPM]":"13.7","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"3.2","Cell RNA - OE19 [nTPM]":"8.1","Cell RNA - PC-3 [nTPM]":"3.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"22.8","Cell RNA - RPTEC TERT1 [nTPM]":"27.7","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"53.5","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"6.0","Cell RNA - T-47d [nTPM]":"24.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"68.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"7.5","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"1.5","Cell RNA - WM-115 [nTPM]":"31.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"7.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"10.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.3","Blood RNA - memory CD8 T-cell [nTPM]":"5.6","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"14.7","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"10.3","Brain RNA - cerebral cortex [nTPM]":"22.2","Brain RNA - hippocampal formation [nTPM]":"12.0","Brain RNA - hypothalamus [nTPM]":"9.8","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"12.4","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"10.6","Brain RNA - thalamus [nTPM]":"16.0","Brain RNA - white matter [nTPM]":"9.4","Single Cell Type RNA - Adipocytes [nTPM]":"75.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - dendritic cells [nTPM]":"4.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"20.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"60.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.6","Single Cell Type RNA - Langerhans cells [nTPM]":"44.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"25.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"PDGFRB","Gene synonym":["CD140b","JTK12","PDGFR","PDGFR1"],"Ensembl":"ENSG00000113721","Gene description":"Platelet derived growth factor receptor beta","Uniprot":["P09619"],"Chromosome":"5","Position":"150113839-150155872","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Chemotaxis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Sertoli cells":"1288.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"ASC diff":"1350.1","ASC TERT1":"462.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003842","CAB018144","HPA028499"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"39000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB003842":"AB_562328","CAB018144":"AB_2162497","HPA028499":"AB_10602018"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.87e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.11e-4"},"Tissue RNA - adipose tissue [nTPM]":"171.2","Tissue RNA - adrenal gland [nTPM]":"25.1","Tissue RNA - amygdala [nTPM]":"25.4","Tissue RNA - appendix [nTPM]":"27.5","Tissue RNA - basal ganglia [nTPM]":"27.2","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"106.3","Tissue RNA - cerebellum [nTPM]":"20.5","Tissue RNA - cerebral cortex [nTPM]":"33.3","Tissue RNA - cervix [nTPM]":"155.9","Tissue RNA - choroid plexus [nTPM]":"43.5","Tissue RNA - colon [nTPM]":"41.6","Tissue RNA - duodenum [nTPM]":"11.9","Tissue RNA - endometrium 1 [nTPM]":"101.1","Tissue RNA - epididymis [nTPM]":"24.2","Tissue RNA - esophagus [nTPM]":"24.1","Tissue RNA - fallopian tube [nTPM]":"89.6","Tissue RNA - gallbladder [nTPM]":"124.5","Tissue RNA - heart muscle [nTPM]":"75.7","Tissue RNA - hippocampal formation [nTPM]":"22.1","Tissue RNA - hypothalamus [nTPM]":"23.2","Tissue RNA - kidney [nTPM]":"49.7","Tissue RNA - liver [nTPM]":"13.4","Tissue RNA - lung [nTPM]":"98.3","Tissue RNA - lymph node [nTPM]":"27.5","Tissue RNA - medulla oblongata [nTPM]":"22.1","Tissue RNA - midbrain [nTPM]":"24.6","Tissue RNA - ovary [nTPM]":"105.5","Tissue RNA - pancreas [nTPM]":"20.8","Tissue RNA - parathyroid gland [nTPM]":"21.9","Tissue RNA - pituitary gland [nTPM]":"23.0","Tissue RNA - placenta [nTPM]":"113.3","Tissue RNA - pons [nTPM]":"22.8","Tissue RNA - prostate [nTPM]":"56.2","Tissue RNA - rectum [nTPM]":"14.1","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"34.5","Tissue RNA - seminal vesicle [nTPM]":"43.3","Tissue RNA - skeletal muscle [nTPM]":"38.1","Tissue RNA - skin 1 [nTPM]":"65.0","Tissue RNA - small intestine [nTPM]":"37.9","Tissue RNA - smooth muscle [nTPM]":"68.9","Tissue RNA - spinal cord [nTPM]":"19.4","Tissue RNA - spleen [nTPM]":"41.4","Tissue RNA - stomach 1 [nTPM]":"27.9","Tissue RNA - testis [nTPM]":"18.4","Tissue RNA - thalamus [nTPM]":"27.7","Tissue RNA - thymus [nTPM]":"8.7","Tissue RNA - thyroid gland [nTPM]":"66.5","Tissue RNA - tongue [nTPM]":"44.1","Tissue RNA - tonsil [nTPM]":"13.8","Tissue RNA - urinary bladder [nTPM]":"58.3","Tissue RNA - vagina [nTPM]":"98.6","Tissue RNA - white matter [nTPM]":"21.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"8.3","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"1350.1","Cell RNA - ASC TERT1 [nTPM]":"462.7","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"48.9","Cell RNA - BJ hTERT+ [nTPM]":"202.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.4","Cell RNA - CACO-2 [nTPM]":"5.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"142.0","Cell RNA - GAMG [nTPM]":"19.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"15.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"190.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"210.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.3","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"106.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"5.5","Cell RNA - LHCN-M2 [nTPM]":"5.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"9.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"3.7","Cell RNA - RH-30 [nTPM]":"2.5","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"24.8","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"38.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"53.7","Cell RNA - U-2 OS [nTPM]":"17.2","Cell RNA - U-2197 [nTPM]":"23.1","Cell RNA - U-251 MG [nTPM]":"2.8","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"33.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"25.4","Brain RNA - basal ganglia [nTPM]":"27.2","Brain RNA - cerebellum [nTPM]":"20.5","Brain RNA - cerebral cortex [nTPM]":"33.3","Brain RNA - hippocampal formation [nTPM]":"22.1","Brain RNA - hypothalamus [nTPM]":"23.2","Brain RNA - medulla oblongata [nTPM]":"22.1","Brain RNA - midbrain [nTPM]":"24.6","Brain RNA - pons [nTPM]":"22.8","Brain RNA - spinal cord [nTPM]":"19.4","Brain RNA - thalamus [nTPM]":"27.7","Brain RNA - white matter [nTPM]":"21.6","Single Cell Type RNA - Adipocytes [nTPM]":"50.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"81.9","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"99.5","Single Cell Type RNA - Endothelial cells [nTPM]":"32.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"123.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"35.6","Single Cell Type RNA - Late spermatids [nTPM]":"10.9","Single Cell Type RNA - Leydig cells [nTPM]":"165.3","Single Cell Type RNA - Macrophages [nTPM]":"3.1","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"50.7","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"203.8","Single Cell Type RNA - Plasma cells [nTPM]":"2.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.9","Single Cell Type RNA - Sertoli cells [nTPM]":"1288.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"288.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"4.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"PDK3","Gene synonym":[],"Ensembl":"ENSG00000067992","Gene description":"Pyruvate dehydrogenase kinase 3","Uniprot":["Q15120"],"Chromosome":"X","Position":"24465270-24550466","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"71.6","Excitatory neurons":"92.8","Inhibitory neurons":"78.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046583","HPA072492"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA046583":"AB_2679707","HPA072492":"AB_2686526"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.76e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"8.9","Tissue RNA - breast [nTPM]":"8.8","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"8.2","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"10.9","Tissue RNA - esophagus [nTPM]":"3.9","Tissue RNA - fallopian tube [nTPM]":"5.9","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"7.4","Tissue RNA - hippocampal formation [nTPM]":"13.2","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"8.8","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"7.9","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"5.8","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"5.3","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"11.1","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"6.8","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"7.7","Tissue RNA - stomach 1 [nTPM]":"6.9","Tissue RNA - testis [nTPM]":"11.6","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"11.5","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"4.2","Cell RNA - AN3-CA [nTPM]":"8.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"5.0","Cell RNA - BJ [nTPM]":"3.4","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.9","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"13.9","Cell RNA - Daudi [nTPM]":"10.4","Cell RNA - EFO-21 [nTPM]":"2.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"11.6","Cell RNA - HaCaT [nTPM]":"2.1","Cell RNA - HAP1 [nTPM]":"12.3","Cell RNA - HBEC3-KT [nTPM]":"8.4","Cell RNA - HBF TERT88 [nTPM]":"10.4","Cell RNA - HDLM-2 [nTPM]":"9.7","Cell RNA - HEK 293 [nTPM]":"6.0","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"6.1","Cell RNA - Hep G2 [nTPM]":"3.3","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"4.6","Cell RNA - HMC-1 [nTPM]":"5.8","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"3.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"1.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"6.8","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"16.5","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"20.9","Cell RNA - MOLT-4 [nTPM]":"9.4","Cell RNA - NB-4 [nTPM]":"6.0","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"12.2","Cell RNA - PC-3 [nTPM]":"5.6","Cell RNA - REH [nTPM]":"5.0","Cell RNA - RH-30 [nTPM]":"8.0","Cell RNA - RPMI-8226 [nTPM]":"17.3","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"21.4","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"4.0","Cell RNA - SiHa [nTPM]":"17.9","Cell RNA - SK-BR-3 [nTPM]":"8.0","Cell RNA - SK-MEL-30 [nTPM]":"5.5","Cell RNA - SuSa [nTPM]":"7.3","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"3.3","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"5.8","Cell RNA - U-251 MG [nTPM]":"4.2","Cell RNA - U-266\/70 [nTPM]":"11.0","Cell RNA - U-266\/84 [nTPM]":"8.9","Cell RNA - U-698 [nTPM]":"12.9","Cell RNA - U-87 MG [nTPM]":"8.7","Cell RNA - U-937 [nTPM]":"7.7","Cell RNA - WM-115 [nTPM]":"6.4","Blood RNA - basophil [nTPM]":"13.3","Blood RNA - classical monocyte [nTPM]":"15.4","Blood RNA - eosinophil [nTPM]":"37.9","Blood RNA - gdT-cell [nTPM]":"11.8","Blood RNA - intermediate monocyte [nTPM]":"19.6","Blood RNA - MAIT T-cell [nTPM]":"16.5","Blood RNA - memory B-cell [nTPM]":"7.5","Blood RNA - memory CD4 T-cell [nTPM]":"9.1","Blood RNA - memory CD8 T-cell [nTPM]":"10.3","Blood RNA - myeloid DC [nTPM]":"12.2","Blood RNA - naive B-cell [nTPM]":"7.3","Blood RNA - naive CD4 T-cell [nTPM]":"7.6","Blood RNA - naive CD8 T-cell [nTPM]":"8.6","Blood RNA - neutrophil [nTPM]":"57.6","Blood RNA - NK-cell [nTPM]":"13.3","Blood RNA - non-classical monocyte [nTPM]":"18.8","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"12.4","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"13.2","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"15.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"5.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - dendritic cells [nTPM]":"16.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"71.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.9","Single Cell Type RNA - Endothelial cells [nTPM]":"3.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"92.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"5.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"78.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"35.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"17.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"3.7","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"19.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.2","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.8","Single Cell Type RNA - T-cells [nTPM]":"18.2","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"8.4"},{"Gene":"PDSS1","Gene synonym":["COQ1","COQ1A","TPRT","TPT"],"Ensembl":"ENSG00000148459","Gene description":"Decaprenyl diphosphate synthase subunit 1","Uniprot":["Q5T2R2"],"Chromosome":"10","Position":"26697701-26746798","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Isoprene biosynthesis","Ubiquinone biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"19.1","lymphoid tissue":"13.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"32.5","Proximal enterocytes":"29.8","Undifferentiated cells":"29.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038032","HPA042741"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038032":"AB_10670650","HPA042741":"AB_2678139"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"14.1","Tissue RNA - duodenum [nTPM]":"19.1","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"4.3","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"3.6","Tissue RNA - lung [nTPM]":"2.2","Tissue RNA - lymph node [nTPM]":"4.0","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"2.2","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"15.1","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"5.7","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"15.3","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"13.8","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"3.1","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"15.6","Cell RNA - A549 [nTPM]":"11.8","Cell RNA - AF22 [nTPM]":"8.9","Cell RNA - AN3-CA [nTPM]":"16.3","Cell RNA - ASC diff [nTPM]":"2.9","Cell RNA - ASC TERT1 [nTPM]":"5.4","Cell RNA - BEWO [nTPM]":"12.2","Cell RNA - BJ [nTPM]":"14.0","Cell RNA - BJ hTERT+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.7","Cell RNA - CACO-2 [nTPM]":"18.3","Cell RNA - CAPAN-2 [nTPM]":"8.4","Cell RNA - Daudi [nTPM]":"35.0","Cell RNA - EFO-21 [nTPM]":"7.2","Cell RNA - fHDF\/TERT166 [nTPM]":"7.0","Cell RNA - GAMG [nTPM]":"7.6","Cell RNA - HaCaT [nTPM]":"19.2","Cell RNA - HAP1 [nTPM]":"28.6","Cell RNA - HBEC3-KT [nTPM]":"21.8","Cell RNA - HBF TERT88 [nTPM]":"16.7","Cell RNA - HDLM-2 [nTPM]":"14.7","Cell RNA - HEK 293 [nTPM]":"23.6","Cell RNA - HEL [nTPM]":"30.4","Cell RNA - HeLa [nTPM]":"9.9","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"20.3","Cell RNA - HMC-1 [nTPM]":"11.6","Cell RNA - HSkMC [nTPM]":"6.8","Cell RNA - hTCEpi [nTPM]":"9.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.0","Cell RNA - hTERT-HME1 [nTPM]":"5.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.5","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"22.8","Cell RNA - K-562 [nTPM]":"28.4","Cell RNA - Karpas-707 [nTPM]":"9.3","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"24.9","Cell RNA - MOLT-4 [nTPM]":"64.6","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"17.9","Cell RNA - OE19 [nTPM]":"24.9","Cell RNA - PC-3 [nTPM]":"11.3","Cell RNA - REH [nTPM]":"29.6","Cell RNA - RH-30 [nTPM]":"25.1","Cell RNA - RPMI-8226 [nTPM]":"25.5","Cell RNA - RPTEC TERT1 [nTPM]":"12.0","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"25.7","Cell RNA - SH-SY5Y [nTPM]":"15.8","Cell RNA - SiHa [nTPM]":"13.5","Cell RNA - SK-BR-3 [nTPM]":"27.6","Cell RNA - SK-MEL-30 [nTPM]":"15.9","Cell RNA - SuSa [nTPM]":"9.2","Cell RNA - T-47d [nTPM]":"9.9","Cell RNA - THP-1 [nTPM]":"23.7","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"11.1","Cell RNA - U-2 OS [nTPM]":"17.9","Cell RNA - U-2197 [nTPM]":"22.9","Cell RNA - U-251 MG [nTPM]":"22.5","Cell RNA - U-266\/70 [nTPM]":"3.6","Cell RNA - U-266\/84 [nTPM]":"14.1","Cell RNA - U-698 [nTPM]":"25.6","Cell RNA - U-87 MG [nTPM]":"10.9","Cell RNA - U-937 [nTPM]":"51.3","Cell RNA - WM-115 [nTPM]":"8.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"3.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"18.9","Single Cell Type RNA - B-cells [nTPM]":"4.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"4.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"12.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.8","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"4.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"6.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.6","Single Cell Type RNA - Paneth cells [nTPM]":"9.8","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.5","Single Cell Type RNA - Spermatocytes [nTPM]":"12.5","Single Cell Type RNA - Spermatogonia [nTPM]":"9.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"PDSS2","Gene synonym":["bA59I9.3","C6orf210","COQ1B"],"Ensembl":"ENSG00000164494","Gene description":"Decaprenyl diphosphate synthase subunit 2","Uniprot":["Q86YH6"],"Chromosome":"6","Position":"107152562-107459564","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Isoprene biosynthesis","Ubiquinone biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"82.4","Oligodendrocyte precursor cells":"72.9","Oligodendrocytes":"74.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029685","HPA029686"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029685":"AB_10600219","HPA029686":"AB_10602309"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.74e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.75e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"9.2","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"9.3","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"8.7","Tissue RNA - heart muscle [nTPM]":"13.9","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"21.6","Tissue RNA - liver [nTPM]":"27.1","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"9.1","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"13.2","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"6.8","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"15.3","Tissue RNA - seminal vesicle [nTPM]":"7.4","Tissue RNA - skeletal muscle [nTPM]":"12.5","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"8.5","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"7.7","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"13.7","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"7.6","Cell RNA - A549 [nTPM]":"10.0","Cell RNA - AF22 [nTPM]":"8.3","Cell RNA - AN3-CA [nTPM]":"13.2","Cell RNA - ASC diff [nTPM]":"14.2","Cell RNA - ASC TERT1 [nTPM]":"18.0","Cell RNA - BEWO [nTPM]":"19.2","Cell RNA - BJ [nTPM]":"13.1","Cell RNA - BJ hTERT+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.8","Cell RNA - CACO-2 [nTPM]":"10.0","Cell RNA - CAPAN-2 [nTPM]":"10.8","Cell RNA - Daudi [nTPM]":"14.4","Cell RNA - EFO-21 [nTPM]":"11.7","Cell RNA - fHDF\/TERT166 [nTPM]":"14.7","Cell RNA - GAMG [nTPM]":"13.1","Cell RNA - HaCaT [nTPM]":"10.2","Cell RNA - HAP1 [nTPM]":"20.3","Cell RNA - HBEC3-KT [nTPM]":"16.5","Cell RNA - HBF TERT88 [nTPM]":"16.7","Cell RNA - HDLM-2 [nTPM]":"9.1","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"14.4","Cell RNA - HeLa [nTPM]":"11.4","Cell RNA - Hep G2 [nTPM]":"16.9","Cell RNA - HHSteC [nTPM]":"15.0","Cell RNA - HL-60 [nTPM]":"18.5","Cell RNA - HMC-1 [nTPM]":"11.1","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"19.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.5","Cell RNA - hTERT-HME1 [nTPM]":"15.3","Cell RNA - hTERT-RPE1 [nTPM]":"10.8","Cell RNA - HUVEC TERT2 [nTPM]":"13.1","Cell RNA - JURKAT [nTPM]":"16.5","Cell RNA - K-562 [nTPM]":"20.7","Cell RNA - Karpas-707 [nTPM]":"19.0","Cell RNA - LHCN-M2 [nTPM]":"12.2","Cell RNA - MCF7 [nTPM]":"9.3","Cell RNA - MOLT-4 [nTPM]":"5.4","Cell RNA - NB-4 [nTPM]":"19.7","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"17.3","Cell RNA - PC-3 [nTPM]":"12.7","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"7.4","Cell RNA - RPMI-8226 [nTPM]":"11.7","Cell RNA - RPTEC TERT1 [nTPM]":"15.2","Cell RNA - RT4 [nTPM]":"10.2","Cell RNA - SCLC-21H [nTPM]":"8.2","Cell RNA - SH-SY5Y [nTPM]":"7.1","Cell RNA - SiHa [nTPM]":"9.0","Cell RNA - SK-BR-3 [nTPM]":"15.4","Cell RNA - SK-MEL-30 [nTPM]":"19.7","Cell RNA - SuSa [nTPM]":"9.0","Cell RNA - T-47d [nTPM]":"12.7","Cell RNA - THP-1 [nTPM]":"22.3","Cell RNA - TIME [nTPM]":"8.3","Cell RNA - U-138 MG [nTPM]":"8.8","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"12.4","Cell RNA - U-251 MG [nTPM]":"11.4","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"6.8","Cell RNA - U-698 [nTPM]":"11.3","Cell RNA - U-87 MG [nTPM]":"16.3","Cell RNA - U-937 [nTPM]":"27.4","Cell RNA - WM-115 [nTPM]":"16.3","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"5.1","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"5.9","Blood RNA - MAIT T-cell [nTPM]":"5.9","Blood RNA - memory B-cell [nTPM]":"4.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"4.7","Blood RNA - myeloid DC [nTPM]":"7.0","Blood RNA - naive B-cell [nTPM]":"5.5","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"9.9","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"11.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.1","Single Cell Type RNA - Astrocytes [nTPM]":"64.9","Single Cell Type RNA - B-cells [nTPM]":"12.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"13.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.9","Single Cell Type RNA - dendritic cells [nTPM]":"8.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"12.7","Single Cell Type RNA - Early spermatids [nTPM]":"37.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.9","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"32.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"67.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"12.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"82.4","Single Cell Type RNA - monocytes [nTPM]":"8.5","Single Cell Type RNA - Muller glia cells [nTPM]":"11.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"72.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"74.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.7","Single Cell Type RNA - Paneth cells [nTPM]":"14.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.9","Single Cell Type RNA - Spermatocytes [nTPM]":"21.7","Single Cell Type RNA - Spermatogonia [nTPM]":"11.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - T-cells [nTPM]":"9.8","Single Cell Type RNA - Theca cells [nTPM]":"13.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.5"},{"Gene":"PDYN","Gene synonym":["ADCA","PENKB","SCA23"],"Ensembl":"ENSG00000101327","Gene description":"Prodynorphin","Uniprot":["P01213"],"Chromosome":"20","Position":"1978757-1994285","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Endorphin","Neuropeptide","Neurotransmitter","Opioid peptide"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"47.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"83","RNA single cell type specific nTPM":{"Early spermatids":"47.8","Late spermatids":"119.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"29","RNA cancer specific FPKM":{"glioma":"2.6","ovarian cancer":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"THP-1":"1.0"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"152.2","hypothalamus":"60.7"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"132.2"},"Antibody":["HPA053342","CAB079777"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079777":null,"HPA053342":"AB_2682121"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"43.2","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"31.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"43.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"47.0","Tissue RNA - hypothalamus [nTPM]":"17.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"21.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"43.2","Brain RNA - basal ganglia [nTPM]":"31.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"43.1","Brain RNA - hippocampal formation [nTPM]":"47.0","Brain RNA - hypothalamus [nTPM]":"17.6","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"21.0","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"47.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"119.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PDZD7","Gene synonym":["bA108L7.8","DFNB57","FLJ23209","PDZK7"],"Ensembl":"ENSG00000186862","Gene description":"PDZ domain containing 7","Uniprot":["Q9H5P4"],"Chromosome":"10","Position":"101007679-101032295","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"21.5","intestine":"20.0","pituitary gland":"6.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"15.9","Cone photoreceptor cells":"22.9","Excitatory neurons":"32.3","Inhibitory neurons":"16.5","Proximal enterocytes":"56.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"7.5","SCLC-21H":"11.7","THP-1":"18.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074542"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA074542":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"10.2","Tissue RNA - cerebral cortex [nTPM]":"15.4","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"12.8","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"5.7","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"1.5","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"21.5","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"21.0","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"20.0","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"8.8","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"7.5","Cell RNA - A549 [nTPM]":"0.9","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"2.3","Cell RNA - BJ [nTPM]":"1.2","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"3.1","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"4.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"3.3","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"1.5","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.8","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"11.7","Cell RNA - SH-SY5Y [nTPM]":"5.4","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"2.4","Cell RNA - THP-1 [nTPM]":"18.2","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"2.4","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"1.0","Cell RNA - U-266\/70 [nTPM]":"1.5","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"6.4","Cell RNA - U-937 [nTPM]":"1.2","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"10.2","Brain RNA - cerebral cortex [nTPM]":"15.4","Brain RNA - hippocampal formation [nTPM]":"5.7","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"21.5","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"21.0","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"8.8","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"56.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"PER2","Gene synonym":["KIAA0347"],"Ensembl":"ENSG00000132326","Gene description":"Period circadian regulator 2","Uniprot":["O15055"],"Chromosome":"2","Position":"238244044-238290102","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"110.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053136","HPA060510"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA053136":null,"HPA060510":"AB_2684298"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.2","Tissue RNA - adrenal gland [nTPM]":"3.3","Tissue RNA - amygdala [nTPM]":"4.7","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"8.4","Tissue RNA - breast [nTPM]":"14.2","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"11.9","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"7.6","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"13.6","Tissue RNA - fallopian tube [nTPM]":"7.9","Tissue RNA - gallbladder [nTPM]":"12.3","Tissue RNA - heart muscle [nTPM]":"5.7","Tissue RNA - hippocampal formation [nTPM]":"5.7","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"12.4","Tissue RNA - lung [nTPM]":"7.1","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"5.7","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"14.4","Tissue RNA - parathyroid gland [nTPM]":"4.2","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"2.9","Tissue RNA - pons [nTPM]":"4.4","Tissue RNA - prostate [nTPM]":"9.3","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"5.1","Tissue RNA - salivary gland [nTPM]":"14.1","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"17.0","Tissue RNA - small intestine [nTPM]":"8.0","Tissue RNA - smooth muscle [nTPM]":"4.9","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"4.8","Tissue RNA - stomach 1 [nTPM]":"13.4","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"8.2","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"11.7","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"4.2","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"1.2","Cell RNA - BEWO [nTPM]":"8.2","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"5.8","Cell RNA - Daudi [nTPM]":"10.3","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"2.7","Cell RNA - GAMG [nTPM]":"1.5","Cell RNA - HaCaT [nTPM]":"8.6","Cell RNA - HAP1 [nTPM]":"2.4","Cell RNA - HBEC3-KT [nTPM]":"3.5","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"2.9","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"9.1","Cell RNA - HeLa [nTPM]":"6.2","Cell RNA - Hep G2 [nTPM]":"8.2","Cell RNA - HHSteC [nTPM]":"2.0","Cell RNA - HL-60 [nTPM]":"13.8","Cell RNA - HMC-1 [nTPM]":"9.2","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"8.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"6.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.8","Cell RNA - JURKAT [nTPM]":"4.2","Cell RNA - K-562 [nTPM]":"4.5","Cell RNA - Karpas-707 [nTPM]":"6.3","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"7.7","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"15.2","Cell RNA - NTERA-2 [nTPM]":"3.5","Cell RNA - OE19 [nTPM]":"7.6","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"16.5","Cell RNA - RH-30 [nTPM]":"5.5","Cell RNA - RPMI-8226 [nTPM]":"3.3","Cell RNA - RPTEC TERT1 [nTPM]":"1.5","Cell RNA - RT4 [nTPM]":"3.3","Cell RNA - SCLC-21H [nTPM]":"9.7","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"2.9","Cell RNA - SK-BR-3 [nTPM]":"6.3","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"5.9","Cell RNA - THP-1 [nTPM]":"8.5","Cell RNA - TIME [nTPM]":"2.1","Cell RNA - U-138 MG [nTPM]":"3.6","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"2.8","Cell RNA - U-251 MG [nTPM]":"4.1","Cell RNA - U-266\/70 [nTPM]":"7.1","Cell RNA - U-266\/84 [nTPM]":"1.8","Cell RNA - U-698 [nTPM]":"12.3","Cell RNA - U-87 MG [nTPM]":"6.7","Cell RNA - U-937 [nTPM]":"5.9","Cell RNA - WM-115 [nTPM]":"4.5","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"4.7","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"5.7","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"5.7","Brain RNA - pons [nTPM]":"4.4","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"24.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.1","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"9.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"73.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"61.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"20.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"67.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"46.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - dendritic cells [nTPM]":"27.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.5","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"69.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.1","Single Cell Type RNA - Endothelial cells [nTPM]":"15.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.6","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"39.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"86.1","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"35.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.9","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"25.3","Single Cell Type RNA - Late spermatids [nTPM]":"4.7","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"12.4","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"5.3","Single Cell Type RNA - Muller glia cells [nTPM]":"13.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"35.3","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"10.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"44.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"110.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.2","Single Cell Type RNA - Spermatocytes [nTPM]":"31.3","Single Cell Type RNA - Spermatogonia [nTPM]":"17.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"85.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.0","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.9","Single Cell Type RNA - Urothelial cells [nTPM]":"33.9"},{"Gene":"PER3","Gene synonym":[],"Ensembl":"ENSG00000049246","Gene description":"Period circadian regulator 3","Uniprot":["P56645"],"Chromosome":"1","Position":"7784320-7845177","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"137.8","Bipolar cells":"241.0","Horizontal cells":"124.5","Rod photoreceptor cells":"138.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-937":"36.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019530"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019530":"AB_1855201"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.14e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.9","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"12.6","Tissue RNA - cerebellum [nTPM]":"46.1","Tissue RNA - cerebral cortex [nTPM]":"15.9","Tissue RNA - cervix [nTPM]":"12.4","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"18.4","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"19.0","Tissue RNA - epididymis [nTPM]":"10.6","Tissue RNA - esophagus [nTPM]":"17.0","Tissue RNA - fallopian tube [nTPM]":"12.6","Tissue RNA - gallbladder [nTPM]":"12.2","Tissue RNA - heart muscle [nTPM]":"22.3","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"9.9","Tissue RNA - kidney [nTPM]":"12.5","Tissue RNA - liver [nTPM]":"25.6","Tissue RNA - lung [nTPM]":"12.0","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"12.7","Tissue RNA - midbrain [nTPM]":"13.9","Tissue RNA - ovary [nTPM]":"18.5","Tissue RNA - pancreas [nTPM]":"17.0","Tissue RNA - parathyroid gland [nTPM]":"19.8","Tissue RNA - pituitary gland [nTPM]":"16.9","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"14.4","Tissue RNA - prostate [nTPM]":"15.6","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"55.9","Tissue RNA - salivary gland [nTPM]":"25.4","Tissue RNA - seminal vesicle [nTPM]":"20.5","Tissue RNA - skeletal muscle [nTPM]":"28.7","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"9.4","Tissue RNA - smooth muscle [nTPM]":"10.7","Tissue RNA - spinal cord [nTPM]":"11.8","Tissue RNA - spleen [nTPM]":"9.0","Tissue RNA - stomach 1 [nTPM]":"17.4","Tissue RNA - testis [nTPM]":"8.8","Tissue RNA - thalamus [nTPM]":"14.4","Tissue RNA - thymus [nTPM]":"4.6","Tissue RNA - thyroid gland [nTPM]":"23.3","Tissue RNA - tongue [nTPM]":"24.3","Tissue RNA - tonsil [nTPM]":"7.2","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"26.0","Cell RNA - A-431 [nTPM]":"7.2","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"6.1","Cell RNA - AN3-CA [nTPM]":"1.8","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"3.0","Cell RNA - BJ hTERT+ [nTPM]":"5.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.6","Cell RNA - CACO-2 [nTPM]":"8.6","Cell RNA - CAPAN-2 [nTPM]":"27.7","Cell RNA - Daudi [nTPM]":"3.2","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"12.4","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"3.3","Cell RNA - HAP1 [nTPM]":"22.1","Cell RNA - HBEC3-KT [nTPM]":"1.4","Cell RNA - HBF TERT88 [nTPM]":"8.3","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"22.7","Cell RNA - HeLa [nTPM]":"8.3","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"6.8","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"7.6","Cell RNA - HSkMC [nTPM]":"3.0","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"6.1","Cell RNA - hTERT-RPE1 [nTPM]":"11.4","Cell RNA - HUVEC TERT2 [nTPM]":"2.0","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"18.7","Cell RNA - Karpas-707 [nTPM]":"5.8","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"5.7","Cell RNA - MOLT-4 [nTPM]":"12.7","Cell RNA - NB-4 [nTPM]":"10.2","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"16.0","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"2.2","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"3.1","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"7.9","Cell RNA - SH-SY5Y [nTPM]":"8.5","Cell RNA - SiHa [nTPM]":"26.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"11.0","Cell RNA - SuSa [nTPM]":"6.1","Cell RNA - T-47d [nTPM]":"6.6","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"4.2","Cell RNA - U-138 MG [nTPM]":"14.9","Cell RNA - U-2 OS [nTPM]":"21.4","Cell RNA - U-2197 [nTPM]":"4.6","Cell RNA - U-251 MG [nTPM]":"4.0","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"2.7","Cell RNA - U-87 MG [nTPM]":"10.5","Cell RNA - U-937 [nTPM]":"36.0","Cell RNA - WM-115 [nTPM]":"21.2","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"46.1","Brain RNA - cerebral cortex [nTPM]":"15.9","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"9.9","Brain RNA - medulla oblongata [nTPM]":"12.7","Brain RNA - midbrain [nTPM]":"13.9","Brain RNA - pons [nTPM]":"14.4","Brain RNA - spinal cord [nTPM]":"11.8","Brain RNA - thalamus [nTPM]":"14.4","Brain RNA - white matter [nTPM]":"26.0","Single Cell Type RNA - Adipocytes [nTPM]":"45.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.1","Single Cell Type RNA - Astrocytes [nTPM]":"137.8","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.5","Single Cell Type RNA - Bipolar cells [nTPM]":"241.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"9.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"81.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.7","Single Cell Type RNA - dendritic cells [nTPM]":"3.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"3.2","Single Cell Type RNA - Early spermatids [nTPM]":"16.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.6","Single Cell Type RNA - Endothelial cells [nTPM]":"17.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"33.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.3","Single Cell Type RNA - granulocytes [nTPM]":"26.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"28.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"124.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"64.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.5","Single Cell Type RNA - Langerhans cells [nTPM]":"14.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.8","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"11.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"3.4","Single Cell Type RNA - Muller glia cells [nTPM]":"91.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"62.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"91.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"27.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"138.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.4","Single Cell Type RNA - Spermatocytes [nTPM]":"22.2","Single Cell Type RNA - Spermatogonia [nTPM]":"23.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"5.9","Single Cell Type RNA - Theca cells [nTPM]":"11.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"8.6"},{"Gene":"PEX7","Gene synonym":["PTS2R","RD"],"Ensembl":"ENSG00000112357","Gene description":"Peroxisomal biogenesis factor 7","Uniprot":["O00628"],"Chromosome":"6","Position":"136822564-136913934","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Cataract","Deafness","Disease variant","Ichthyosis","Peroxisome biogenesis disorder","Retinitis pigmentosa","Rhizomelic chondrodysplasia punctata"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"60.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049202"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049202":"AB_2680674"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"14.8","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"11.9","Tissue RNA - cerebellum [nTPM]":"6.0","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"7.9","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"17.2","Tissue RNA - esophagus [nTPM]":"7.3","Tissue RNA - fallopian tube [nTPM]":"8.7","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"4.2","Tissue RNA - kidney [nTPM]":"15.6","Tissue RNA - liver [nTPM]":"9.1","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"26.9","Tissue RNA - parathyroid gland [nTPM]":"17.1","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"10.4","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"10.6","Tissue RNA - seminal vesicle [nTPM]":"6.4","Tissue RNA - skeletal muscle [nTPM]":"10.7","Tissue RNA - skin 1 [nTPM]":"11.2","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"3.3","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"15.6","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"11.0","Tissue RNA - tongue [nTPM]":"9.8","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"4.3","Cell RNA - AF22 [nTPM]":"4.4","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"6.6","Cell RNA - ASC TERT1 [nTPM]":"9.8","Cell RNA - BEWO [nTPM]":"2.4","Cell RNA - BJ [nTPM]":"6.1","Cell RNA - BJ hTERT+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.4","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"11.3","Cell RNA - fHDF\/TERT166 [nTPM]":"8.3","Cell RNA - GAMG [nTPM]":"8.5","Cell RNA - HaCaT [nTPM]":"5.3","Cell RNA - HAP1 [nTPM]":"3.3","Cell RNA - HBEC3-KT [nTPM]":"13.8","Cell RNA - HBF TERT88 [nTPM]":"9.8","Cell RNA - HDLM-2 [nTPM]":"5.7","Cell RNA - HEK 293 [nTPM]":"7.5","Cell RNA - HEL [nTPM]":"6.4","Cell RNA - HeLa [nTPM]":"4.3","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"13.9","Cell RNA - HL-60 [nTPM]":"8.1","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"9.6","Cell RNA - hTCEpi [nTPM]":"13.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"7.9","Cell RNA - hTERT-RPE1 [nTPM]":"8.7","Cell RNA - HUVEC TERT2 [nTPM]":"5.4","Cell RNA - JURKAT [nTPM]":"12.0","Cell RNA - K-562 [nTPM]":"13.0","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"10.6","Cell RNA - MCF7 [nTPM]":"13.4","Cell RNA - MOLT-4 [nTPM]":"3.5","Cell RNA - NB-4 [nTPM]":"7.9","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"13.9","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"4.8","Cell RNA - RH-30 [nTPM]":"3.4","Cell RNA - RPMI-8226 [nTPM]":"5.7","Cell RNA - RPTEC TERT1 [nTPM]":"17.4","Cell RNA - RT4 [nTPM]":"6.4","Cell RNA - SCLC-21H [nTPM]":"8.3","Cell RNA - SH-SY5Y [nTPM]":"10.6","Cell RNA - SiHa [nTPM]":"6.5","Cell RNA - SK-BR-3 [nTPM]":"9.0","Cell RNA - SK-MEL-30 [nTPM]":"8.4","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"5.8","Cell RNA - THP-1 [nTPM]":"7.7","Cell RNA - TIME [nTPM]":"2.5","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"7.3","Cell RNA - U-251 MG [nTPM]":"5.3","Cell RNA - U-266\/70 [nTPM]":"6.9","Cell RNA - U-266\/84 [nTPM]":"5.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"4.2","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"4.9","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"6.0","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"4.2","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.4","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"9.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"14.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"16.5","Single Cell Type RNA - Early spermatids [nTPM]":"12.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.4","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.1","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"7.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"7.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.8","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"6.2","Single Cell Type RNA - Late spermatids [nTPM]":"10.2","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"6.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"11.9","Single Cell Type RNA - Muller glia cells [nTPM]":"20.8","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.7","Single Cell Type RNA - Paneth cells [nTPM]":"13.2","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"3.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.2","Single Cell Type RNA - Spermatocytes [nTPM]":"30.6","Single Cell Type RNA - Spermatogonia [nTPM]":"16.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.1","Single Cell Type RNA - T-cells [nTPM]":"6.6","Single Cell Type RNA - Theca cells [nTPM]":"24.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.2","Single Cell Type RNA - Urothelial cells [nTPM]":"17.4"},{"Gene":"PFN1","Gene synonym":[],"Ensembl":"ENSG00000108518","Gene description":"Profilin 1","Uniprot":["P07737"],"Chromosome":"17","Position":"4945652-4949061","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"5241.0","monocytes":"4824.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037134","CAB037140"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"660000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB037134":"AB_1079599","CAB037140":"AB_1079598"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Tissue RNA - adipose tissue [nTPM]":"573.1","Tissue RNA - adrenal gland [nTPM]":"365.8","Tissue RNA - amygdala [nTPM]":"278.0","Tissue RNA - appendix [nTPM]":"1133.4","Tissue RNA - basal ganglia [nTPM]":"302.0","Tissue RNA - bone marrow [nTPM]":"1613.0","Tissue RNA - breast [nTPM]":"397.0","Tissue RNA - cerebellum [nTPM]":"323.2","Tissue RNA - cerebral cortex [nTPM]":"333.0","Tissue RNA - cervix [nTPM]":"393.7","Tissue RNA - choroid plexus [nTPM]":"289.2","Tissue RNA - colon [nTPM]":"970.2","Tissue RNA - duodenum [nTPM]":"764.0","Tissue RNA - endometrium 1 [nTPM]":"734.4","Tissue RNA - epididymis [nTPM]":"346.4","Tissue RNA - esophagus [nTPM]":"582.7","Tissue RNA - fallopian tube [nTPM]":"500.9","Tissue RNA - gallbladder [nTPM]":"372.7","Tissue RNA - heart muscle [nTPM]":"343.8","Tissue RNA - hippocampal formation [nTPM]":"281.8","Tissue RNA - hypothalamus [nTPM]":"301.5","Tissue RNA - kidney [nTPM]":"460.9","Tissue RNA - liver [nTPM]":"661.6","Tissue RNA - lung [nTPM]":"559.2","Tissue RNA - lymph node [nTPM]":"1357.9","Tissue RNA - medulla oblongata [nTPM]":"347.3","Tissue RNA - midbrain [nTPM]":"325.4","Tissue RNA - ovary [nTPM]":"247.7","Tissue RNA - pancreas [nTPM]":"246.4","Tissue RNA - parathyroid gland [nTPM]":"311.3","Tissue RNA - pituitary gland [nTPM]":"198.9","Tissue RNA - placenta [nTPM]":"581.1","Tissue RNA - pons [nTPM]":"348.6","Tissue RNA - prostate [nTPM]":"419.4","Tissue RNA - rectum [nTPM]":"808.4","Tissue RNA - retina [nTPM]":"71.8","Tissue RNA - salivary gland [nTPM]":"346.9","Tissue RNA - seminal vesicle [nTPM]":"601.4","Tissue RNA - skeletal muscle [nTPM]":"337.9","Tissue RNA - skin 1 [nTPM]":"449.8","Tissue RNA - small intestine [nTPM]":"772.9","Tissue RNA - smooth muscle [nTPM]":"1034.7","Tissue RNA - spinal cord [nTPM]":"315.2","Tissue RNA - spleen [nTPM]":"910.8","Tissue RNA - stomach 1 [nTPM]":"675.1","Tissue RNA - testis [nTPM]":"116.2","Tissue RNA - thalamus [nTPM]":"366.2","Tissue RNA - thymus [nTPM]":"1197.6","Tissue RNA - thyroid gland [nTPM]":"269.2","Tissue RNA - tongue [nTPM]":"238.7","Tissue RNA - tonsil [nTPM]":"1440.0","Tissue RNA - urinary bladder [nTPM]":"842.6","Tissue RNA - vagina [nTPM]":"425.0","Tissue RNA - white matter [nTPM]":"355.2","Cell RNA - A-431 [nTPM]":"3019.5","Cell RNA - A549 [nTPM]":"4276.8","Cell RNA - AF22 [nTPM]":"1461.5","Cell RNA - AN3-CA [nTPM]":"1205.2","Cell RNA - ASC diff [nTPM]":"778.8","Cell RNA - ASC TERT1 [nTPM]":"977.1","Cell RNA - BEWO [nTPM]":"1972.7","Cell RNA - BJ [nTPM]":"2416.8","Cell RNA - BJ hTERT+ [nTPM]":"1970.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2568.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1923.7","Cell RNA - CACO-2 [nTPM]":"1684.1","Cell RNA - CAPAN-2 [nTPM]":"1181.1","Cell RNA - Daudi [nTPM]":"2476.9","Cell RNA - EFO-21 [nTPM]":"1892.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2542.0","Cell RNA - GAMG [nTPM]":"1453.6","Cell RNA - HaCaT [nTPM]":"1825.4","Cell RNA - HAP1 [nTPM]":"1383.6","Cell RNA - HBEC3-KT [nTPM]":"3040.5","Cell RNA - HBF TERT88 [nTPM]":"2049.6","Cell RNA - HDLM-2 [nTPM]":"3560.1","Cell RNA - HEK 293 [nTPM]":"2355.1","Cell RNA - HEL [nTPM]":"2516.6","Cell RNA - HeLa [nTPM]":"2034.3","Cell RNA - Hep G2 [nTPM]":"2225.8","Cell RNA - HHSteC [nTPM]":"2144.0","Cell RNA - HL-60 [nTPM]":"1630.4","Cell RNA - HMC-1 [nTPM]":"5006.0","Cell RNA - HSkMC [nTPM]":"1152.4","Cell RNA - hTCEpi [nTPM]":"1331.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1957.6","Cell RNA - hTERT-HME1 [nTPM]":"1939.8","Cell RNA - hTERT-RPE1 [nTPM]":"1477.6","Cell RNA - HUVEC TERT2 [nTPM]":"2361.3","Cell RNA - JURKAT [nTPM]":"1646.4","Cell RNA - K-562 [nTPM]":"1488.6","Cell RNA - Karpas-707 [nTPM]":"1736.7","Cell RNA - LHCN-M2 [nTPM]":"3150.5","Cell RNA - MCF7 [nTPM]":"1815.0","Cell RNA - MOLT-4 [nTPM]":"2469.9","Cell RNA - NB-4 [nTPM]":"3448.0","Cell RNA - NTERA-2 [nTPM]":"2095.2","Cell RNA - OE19 [nTPM]":"1474.7","Cell RNA - PC-3 [nTPM]":"2297.3","Cell RNA - REH [nTPM]":"2451.9","Cell RNA - RH-30 [nTPM]":"2035.1","Cell RNA - RPMI-8226 [nTPM]":"1494.6","Cell RNA - RPTEC TERT1 [nTPM]":"2491.7","Cell RNA - RT4 [nTPM]":"1909.8","Cell RNA - SCLC-21H [nTPM]":"564.0","Cell RNA - SH-SY5Y [nTPM]":"1586.2","Cell RNA - SiHa [nTPM]":"1910.5","Cell RNA - SK-BR-3 [nTPM]":"1180.9","Cell RNA - SK-MEL-30 [nTPM]":"1679.7","Cell RNA - SuSa [nTPM]":"1226.8","Cell RNA - T-47d [nTPM]":"1121.0","Cell RNA - THP-1 [nTPM]":"1359.7","Cell RNA - TIME [nTPM]":"2731.7","Cell RNA - U-138 MG [nTPM]":"2136.6","Cell RNA - U-2 OS [nTPM]":"1675.1","Cell RNA - U-2197 [nTPM]":"1512.3","Cell RNA - U-251 MG [nTPM]":"3969.3","Cell RNA - U-266\/70 [nTPM]":"931.3","Cell RNA - U-266\/84 [nTPM]":"1070.7","Cell RNA - U-698 [nTPM]":"1799.3","Cell RNA - U-87 MG [nTPM]":"1834.4","Cell RNA - U-937 [nTPM]":"1949.7","Cell RNA - WM-115 [nTPM]":"3316.4","Blood RNA - basophil [nTPM]":"8100.1","Blood RNA - classical monocyte [nTPM]":"8206.3","Blood RNA - eosinophil [nTPM]":"13914.4","Blood RNA - gdT-cell [nTPM]":"9850.0","Blood RNA - intermediate monocyte [nTPM]":"10858.8","Blood RNA - MAIT T-cell [nTPM]":"6780.3","Blood RNA - memory B-cell [nTPM]":"5722.0","Blood RNA - memory CD4 T-cell [nTPM]":"8185.7","Blood RNA - memory CD8 T-cell [nTPM]":"9586.6","Blood RNA - myeloid DC [nTPM]":"9920.0","Blood RNA - naive B-cell [nTPM]":"4970.0","Blood RNA - naive CD4 T-cell [nTPM]":"5238.0","Blood RNA - naive CD8 T-cell [nTPM]":"7604.7","Blood RNA - neutrophil [nTPM]":"9387.0","Blood RNA - NK-cell [nTPM]":"9112.1","Blood RNA - non-classical monocyte [nTPM]":"13547.4","Blood RNA - plasmacytoid DC [nTPM]":"7809.7","Blood RNA - T-reg [nTPM]":"11245.6","Blood RNA - total PBMC [nTPM]":"23570.1","Brain RNA - amygdala [nTPM]":"278.0","Brain RNA - basal ganglia [nTPM]":"302.0","Brain RNA - cerebellum [nTPM]":"323.2","Brain RNA - cerebral cortex [nTPM]":"333.0","Brain RNA - hippocampal formation [nTPM]":"281.8","Brain RNA - hypothalamus [nTPM]":"301.5","Brain RNA - medulla oblongata [nTPM]":"347.3","Brain RNA - midbrain [nTPM]":"325.4","Brain RNA - pons [nTPM]":"348.6","Brain RNA - spinal cord [nTPM]":"315.2","Brain RNA - thalamus [nTPM]":"366.2","Brain RNA - white matter [nTPM]":"355.2","Single Cell Type RNA - Adipocytes [nTPM]":"561.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"112.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"176.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.1","Single Cell Type RNA - B-cells [nTPM]":"1070.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1806.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"873.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3658.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1003.3","Single Cell Type RNA - Bipolar cells [nTPM]":"25.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"767.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"914.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"147.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"457.5","Single Cell Type RNA - Club cells [nTPM]":"1020.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"741.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1911.0","Single Cell Type RNA - dendritic cells [nTPM]":"1725.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1733.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"992.0","Single Cell Type RNA - Ductal cells [nTPM]":"1866.6","Single Cell Type RNA - Early spermatids [nTPM]":"19.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"313.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"546.1","Single Cell Type RNA - Endothelial cells [nTPM]":"806.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"603.7","Single Cell Type RNA - Erythroid cells [nTPM]":"713.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1625.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5241.0","Single Cell Type RNA - Fibroblasts [nTPM]":"599.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"733.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"422.7","Single Cell Type RNA - granulocytes [nTPM]":"486.5","Single Cell Type RNA - Granulosa cells [nTPM]":"291.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"637.5","Single Cell Type RNA - Hepatocytes [nTPM]":"754.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"4094.2","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1399.7","Single Cell Type RNA - Ionocytes [nTPM]":"1452.6","Single Cell Type RNA - Kupffer cells [nTPM]":"1434.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2934.8","Single Cell Type RNA - Late spermatids [nTPM]":"31.0","Single Cell Type RNA - Leydig cells [nTPM]":"263.8","Single Cell Type RNA - Macrophages [nTPM]":"1854.7","Single Cell Type RNA - Melanocytes [nTPM]":"873.4","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"4824.7","Single Cell Type RNA - Muller glia cells [nTPM]":"99.8","Single Cell Type RNA - NK-cells [nTPM]":"3216.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2933.5","Single Cell Type RNA - Paneth cells [nTPM]":"1585.7","Single Cell Type RNA - Peritubular cells [nTPM]":"375.0","Single Cell Type RNA - Plasma cells [nTPM]":"927.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1238.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1472.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1671.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"559.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.8","Single Cell Type RNA - Sertoli cells [nTPM]":"506.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"282.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1838.4","Single Cell Type RNA - Spermatocytes [nTPM]":"97.4","Single Cell Type RNA - Spermatogonia [nTPM]":"355.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1170.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1513.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1682.8","Single Cell Type RNA - T-cells [nTPM]":"1804.7","Single Cell Type RNA - Theca cells [nTPM]":"410.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1355.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1177.9"},{"Gene":"PHACTR1","Gene synonym":["dJ257A7.2","KIAA1733","RPEL1"],"Ensembl":"ENSG00000112137","Gene description":"Phosphatase and actin regulator 1","Uniprot":["Q9C0D0"],"Chromosome":"6","Position":"12716554-13287843","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Actin-binding","Protein phosphatase inhibitor"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"38.0","brain":"52.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"1954.8","Inhibitory neurons":"523.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"10.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"basal ganglia":"52.1","cerebral cortex":"27.3","hippocampal formation":"14.8"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"37.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"B-cells":"13.6","dendritic cells":"37.8","granulocytes":"18.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"74.6","SK-MEL-30":"79.5","U-266\/70":"176.1","U-266\/84":"133.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029755","HPA029756","HPA029757"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA029755":"AB_10600089","HPA029756":"AB_10601852","HPA029757":"AB_10669870"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.48e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.1","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"12.6","Tissue RNA - basal ganglia [nTPM]":"52.1","Tissue RNA - bone marrow [nTPM]":"38.0","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"27.3","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"6.0","Tissue RNA - heart muscle [nTPM]":"18.1","Tissue RNA - hippocampal formation [nTPM]":"14.8","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"13.9","Tissue RNA - lymph node [nTPM]":"14.9","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"6.0","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"3.3","Tissue RNA - small intestine [nTPM]":"3.0","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"3.7","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"23.9","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"4.5","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"14.7","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"5.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.7","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"6.4","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"5.3","Cell RNA - HDLM-2 [nTPM]":"17.3","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"39.5","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"38.1","Cell RNA - HMC-1 [nTPM]":"74.6","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"6.2","Cell RNA - JURKAT [nTPM]":"2.1","Cell RNA - K-562 [nTPM]":"18.6","Cell RNA - Karpas-707 [nTPM]":"31.1","Cell RNA - LHCN-M2 [nTPM]":"4.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"22.4","Cell RNA - NTERA-2 [nTPM]":"5.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"17.7","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"2.9","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"18.3","Cell RNA - SH-SY5Y [nTPM]":"5.8","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"9.9","Cell RNA - SK-MEL-30 [nTPM]":"79.5","Cell RNA - SuSa [nTPM]":"6.1","Cell RNA - T-47d [nTPM]":"21.2","Cell RNA - THP-1 [nTPM]":"8.6","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"176.1","Cell RNA - U-266\/84 [nTPM]":"133.7","Cell RNA - U-698 [nTPM]":"33.5","Cell RNA - U-87 MG [nTPM]":"2.3","Cell RNA - U-937 [nTPM]":"9.8","Cell RNA - WM-115 [nTPM]":"26.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"9.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"6.7","Blood RNA - naive B-cell [nTPM]":"13.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"18.7","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"37.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"52.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"27.3","Brain RNA - hippocampal formation [nTPM]":"14.8","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"48.5","Single Cell Type RNA - Astrocytes [nTPM]":"265.1","Single Cell Type RNA - B-cells [nTPM]":"131.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"43.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"8.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"79.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"59.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.8","Single Cell Type RNA - Endothelial cells [nTPM]":"12.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1954.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"8.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.0","Single Cell Type RNA - granulocytes [nTPM]":"81.2","Single Cell Type RNA - Granulosa cells [nTPM]":"2.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"83.1","Single Cell Type RNA - Horizontal cells [nTPM]":"180.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"523.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"138.2","Single Cell Type RNA - Langerhans cells [nTPM]":"91.5","Single Cell Type RNA - Late spermatids [nTPM]":"79.8","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"188.5","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"114.3","Single Cell Type RNA - monocytes [nTPM]":"20.5","Single Cell Type RNA - Muller glia cells [nTPM]":"28.4","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"186.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"247.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"59.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"8.6","Single Cell Type RNA - Theca cells [nTPM]":"6.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"PHOX2A","Gene synonym":["ARIX","CFEOM2","FEOM2","PMX2A"],"Ensembl":"ENSG00000165462","Gene description":"Paired like homeobox 2A","Uniprot":["O14813"],"Chromosome":"11","Position":"72239077-72245664","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"adrenal gland":"19.9","brain":"18.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Spermatogonia":"2.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"ovarian cancer":"9.3"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"pons":"18.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"226","RNA cell line specific nTPM":{"SH-SY5Y":"569.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053810","HPA065621","HPA078004"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053810":null,"HPA065621":"AB_2685522","HPA078004":"AB_2732367"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"19.9","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"18.3","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"569.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"18.3","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PHOX2B","Gene synonym":["NBPhox","PMX2B"],"Ensembl":"ENSG00000109132","Gene description":"Paired like homeobox 2B","Uniprot":["Q99453"],"Chromosome":"4","Position":"41744082-41748725","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"8.6","brain":"15.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Cardiomyocytes":"1.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"medulla oblongata":"10.1","pons":"15.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"89","RNA cell line specific nTPM":{"SH-SY5Y":"132.7"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"17","RNA mouse brain regional specific nTPM":{"pons and medulla":"5.6"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"18","RNA pig brain regional specific nTPM":{"medulla oblongata":"1.4","pons":"2.0"},"Antibody":["HPA074325","HPA074941"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA074325":"AB_2686678","HPA074941":"AB_2732272"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"10.1","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"15.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"132.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"10.1","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"15.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PHYH","Gene synonym":["PAHX","PHYH1","RD"],"Ensembl":"ENSG00000107537","Gene description":"Phytanoyl-CoA 2-hydroxylase","Uniprot":["O14832"],"Chromosome":"10","Position":"13277796-13302412","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Cataract","Deafness","Disease variant","Ichthyosis","Peroxisome biogenesis disorder","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"667.8","skeletal muscle":"483.6","tongue":"412.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"258.6","Proximal tubular cells":"414.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"78.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"110.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007598","HPA011796"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007598":"AB_1855334","HPA011796":"AB_1855335"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.28e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Tissue RNA - adipose tissue [nTPM]":"57.9","Tissue RNA - adrenal gland [nTPM]":"66.5","Tissue RNA - amygdala [nTPM]":"22.9","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"23.7","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"32.2","Tissue RNA - cerebellum [nTPM]":"23.5","Tissue RNA - cerebral cortex [nTPM]":"28.3","Tissue RNA - cervix [nTPM]":"28.8","Tissue RNA - choroid plexus [nTPM]":"31.7","Tissue RNA - colon [nTPM]":"46.5","Tissue RNA - duodenum [nTPM]":"58.7","Tissue RNA - endometrium 1 [nTPM]":"22.1","Tissue RNA - epididymis [nTPM]":"16.7","Tissue RNA - esophagus [nTPM]":"22.9","Tissue RNA - fallopian tube [nTPM]":"16.7","Tissue RNA - gallbladder [nTPM]":"28.2","Tissue RNA - heart muscle [nTPM]":"126.5","Tissue RNA - hippocampal formation [nTPM]":"21.7","Tissue RNA - hypothalamus [nTPM]":"24.1","Tissue RNA - kidney [nTPM]":"191.4","Tissue RNA - liver [nTPM]":"667.8","Tissue RNA - lung [nTPM]":"17.3","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"21.6","Tissue RNA - midbrain [nTPM]":"24.4","Tissue RNA - ovary [nTPM]":"36.8","Tissue RNA - pancreas [nTPM]":"48.2","Tissue RNA - parathyroid gland [nTPM]":"56.7","Tissue RNA - pituitary gland [nTPM]":"20.9","Tissue RNA - placenta [nTPM]":"19.3","Tissue RNA - pons [nTPM]":"22.8","Tissue RNA - prostate [nTPM]":"22.5","Tissue RNA - rectum [nTPM]":"37.2","Tissue RNA - retina [nTPM]":"28.2","Tissue RNA - salivary gland [nTPM]":"33.7","Tissue RNA - seminal vesicle [nTPM]":"25.4","Tissue RNA - skeletal muscle [nTPM]":"483.6","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"55.8","Tissue RNA - smooth muscle [nTPM]":"23.2","Tissue RNA - spinal cord [nTPM]":"22.7","Tissue RNA - spleen [nTPM]":"12.8","Tissue RNA - stomach 1 [nTPM]":"44.2","Tissue RNA - testis [nTPM]":"15.1","Tissue RNA - thalamus [nTPM]":"26.0","Tissue RNA - thymus [nTPM]":"5.6","Tissue RNA - thyroid gland [nTPM]":"56.0","Tissue RNA - tongue [nTPM]":"412.7","Tissue RNA - tonsil [nTPM]":"5.4","Tissue RNA - urinary bladder [nTPM]":"27.0","Tissue RNA - vagina [nTPM]":"14.8","Tissue RNA - white matter [nTPM]":"23.6","Cell RNA - A-431 [nTPM]":"17.2","Cell RNA - A549 [nTPM]":"35.2","Cell RNA - AF22 [nTPM]":"15.6","Cell RNA - AN3-CA [nTPM]":"22.5","Cell RNA - ASC diff [nTPM]":"110.7","Cell RNA - ASC TERT1 [nTPM]":"69.9","Cell RNA - BEWO [nTPM]":"12.4","Cell RNA - BJ [nTPM]":"17.2","Cell RNA - BJ hTERT+ [nTPM]":"23.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.1","Cell RNA - CACO-2 [nTPM]":"9.1","Cell RNA - CAPAN-2 [nTPM]":"30.3","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"12.9","Cell RNA - fHDF\/TERT166 [nTPM]":"29.0","Cell RNA - GAMG [nTPM]":"47.0","Cell RNA - HaCaT [nTPM]":"7.8","Cell RNA - HAP1 [nTPM]":"20.5","Cell RNA - HBEC3-KT [nTPM]":"20.2","Cell RNA - HBF TERT88 [nTPM]":"11.8","Cell RNA - HDLM-2 [nTPM]":"41.4","Cell RNA - HEK 293 [nTPM]":"10.7","Cell RNA - HEL [nTPM]":"14.9","Cell RNA - HeLa [nTPM]":"9.3","Cell RNA - Hep G2 [nTPM]":"36.6","Cell RNA - HHSteC [nTPM]":"54.8","Cell RNA - HL-60 [nTPM]":"2.5","Cell RNA - HMC-1 [nTPM]":"26.8","Cell RNA - HSkMC [nTPM]":"50.3","Cell RNA - hTCEpi [nTPM]":"28.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.0","Cell RNA - hTERT-HME1 [nTPM]":"8.4","Cell RNA - hTERT-RPE1 [nTPM]":"22.7","Cell RNA - HUVEC TERT2 [nTPM]":"18.7","Cell RNA - JURKAT [nTPM]":"16.8","Cell RNA - K-562 [nTPM]":"8.4","Cell RNA - Karpas-707 [nTPM]":"32.2","Cell RNA - LHCN-M2 [nTPM]":"45.5","Cell RNA - MCF7 [nTPM]":"16.3","Cell RNA - MOLT-4 [nTPM]":"9.2","Cell RNA - NB-4 [nTPM]":"12.1","Cell RNA - NTERA-2 [nTPM]":"14.4","Cell RNA - OE19 [nTPM]":"49.4","Cell RNA - PC-3 [nTPM]":"12.6","Cell RNA - REH [nTPM]":"15.7","Cell RNA - RH-30 [nTPM]":"24.1","Cell RNA - RPMI-8226 [nTPM]":"5.8","Cell RNA - RPTEC TERT1 [nTPM]":"40.6","Cell RNA - RT4 [nTPM]":"21.9","Cell RNA - SCLC-21H [nTPM]":"5.3","Cell RNA - SH-SY5Y [nTPM]":"16.8","Cell RNA - SiHa [nTPM]":"64.8","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"32.9","Cell RNA - SuSa [nTPM]":"12.5","Cell RNA - T-47d [nTPM]":"64.8","Cell RNA - THP-1 [nTPM]":"44.2","Cell RNA - TIME [nTPM]":"6.4","Cell RNA - U-138 MG [nTPM]":"29.5","Cell RNA - U-2 OS [nTPM]":"10.6","Cell RNA - U-2197 [nTPM]":"36.4","Cell RNA - U-251 MG [nTPM]":"11.8","Cell RNA - U-266\/70 [nTPM]":"36.6","Cell RNA - U-266\/84 [nTPM]":"26.3","Cell RNA - U-698 [nTPM]":"3.3","Cell RNA - U-87 MG [nTPM]":"38.3","Cell RNA - U-937 [nTPM]":"18.9","Cell RNA - WM-115 [nTPM]":"11.6","Blood RNA - basophil [nTPM]":"16.3","Blood RNA - classical monocyte [nTPM]":"18.7","Blood RNA - eosinophil [nTPM]":"8.2","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"14.2","Blood RNA - MAIT T-cell [nTPM]":"17.6","Blood RNA - memory B-cell [nTPM]":"11.0","Blood RNA - memory CD4 T-cell [nTPM]":"9.9","Blood RNA - memory CD8 T-cell [nTPM]":"10.4","Blood RNA - myeloid DC [nTPM]":"15.8","Blood RNA - naive B-cell [nTPM]":"5.6","Blood RNA - naive CD4 T-cell [nTPM]":"12.5","Blood RNA - naive CD8 T-cell [nTPM]":"12.7","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"11.2","Blood RNA - plasmacytoid DC [nTPM]":"14.4","Blood RNA - T-reg [nTPM]":"10.5","Blood RNA - total PBMC [nTPM]":"12.3","Brain RNA - amygdala [nTPM]":"22.9","Brain RNA - basal ganglia [nTPM]":"23.7","Brain RNA - cerebellum [nTPM]":"23.5","Brain RNA - cerebral cortex [nTPM]":"28.3","Brain RNA - hippocampal formation [nTPM]":"21.7","Brain RNA - hypothalamus [nTPM]":"24.1","Brain RNA - medulla oblongata [nTPM]":"21.6","Brain RNA - midbrain [nTPM]":"24.4","Brain RNA - pons [nTPM]":"22.8","Brain RNA - spinal cord [nTPM]":"22.7","Brain RNA - thalamus [nTPM]":"26.0","Brain RNA - white matter [nTPM]":"23.6","Single Cell Type RNA - Adipocytes [nTPM]":"53.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.2","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"14.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"47.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"258.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"77.2","Single Cell Type RNA - Club cells [nTPM]":"19.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"137.8","Single Cell Type RNA - dendritic cells [nTPM]":"20.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"72.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"144.8","Single Cell Type RNA - Ductal cells [nTPM]":"40.6","Single Cell Type RNA - Early spermatids [nTPM]":"33.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"29.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.8","Single Cell Type RNA - Erythroid cells [nTPM]":"15.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.3","Single Cell Type RNA - Fibroblasts [nTPM]":"41.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.8","Single Cell Type RNA - granulocytes [nTPM]":"30.4","Single Cell Type RNA - Granulosa cells [nTPM]":"28.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"145.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"55.4","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"57.4","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"22.0","Single Cell Type RNA - Late spermatids [nTPM]":"45.4","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"25.3","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"69.3","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.7","Single Cell Type RNA - Paneth cells [nTPM]":"46.0","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"141.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"414.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.5","Single Cell Type RNA - Spermatocytes [nTPM]":"12.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"83.9","Single Cell Type RNA - T-cells [nTPM]":"25.2","Single Cell Type RNA - Theca cells [nTPM]":"103.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.9","Single Cell Type RNA - Urothelial cells [nTPM]":"18.1"},{"Gene":"PIGB","Gene synonym":[],"Ensembl":"ENSG00000069943","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class B","Uniprot":["Q92521"],"Chromosome":"15","Position":"55318960-55355648","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039929"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039929":"AB_10673539"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.4","Tissue RNA - adrenal gland [nTPM]":"4.8","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"5.8","Tissue RNA - basal ganglia [nTPM]":"2.6","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"9.0","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"5.5","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"7.5","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"11.0","Tissue RNA - esophagus [nTPM]":"5.7","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"9.4","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"8.2","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"4.7","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"10.6","Tissue RNA - pituitary gland [nTPM]":"3.9","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"7.9","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"6.8","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"6.1","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"5.6","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"6.1","Tissue RNA - stomach 1 [nTPM]":"7.6","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"7.5","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"3.1","Cell RNA - A-431 [nTPM]":"10.5","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"5.8","Cell RNA - AN3-CA [nTPM]":"4.1","Cell RNA - ASC diff [nTPM]":"6.6","Cell RNA - ASC TERT1 [nTPM]":"13.2","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"9.0","Cell RNA - BJ hTERT+ [nTPM]":"19.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.8","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"10.9","Cell RNA - EFO-21 [nTPM]":"10.4","Cell RNA - fHDF\/TERT166 [nTPM]":"12.9","Cell RNA - GAMG [nTPM]":"15.6","Cell RNA - HaCaT [nTPM]":"18.3","Cell RNA - HAP1 [nTPM]":"3.3","Cell RNA - HBEC3-KT [nTPM]":"9.5","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"10.4","Cell RNA - HEK 293 [nTPM]":"6.4","Cell RNA - HEL [nTPM]":"10.9","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"6.7","Cell RNA - HHSteC [nTPM]":"11.9","Cell RNA - HL-60 [nTPM]":"30.8","Cell RNA - HMC-1 [nTPM]":"8.7","Cell RNA - HSkMC [nTPM]":"12.5","Cell RNA - hTCEpi [nTPM]":"11.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.9","Cell RNA - hTERT-HME1 [nTPM]":"10.7","Cell RNA - hTERT-RPE1 [nTPM]":"13.8","Cell RNA - HUVEC TERT2 [nTPM]":"13.6","Cell RNA - JURKAT [nTPM]":"9.2","Cell RNA - K-562 [nTPM]":"12.2","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"15.0","Cell RNA - MCF7 [nTPM]":"9.1","Cell RNA - MOLT-4 [nTPM]":"3.4","Cell RNA - NB-4 [nTPM]":"12.8","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"7.9","Cell RNA - PC-3 [nTPM]":"4.8","Cell RNA - REH [nTPM]":"4.9","Cell RNA - RH-30 [nTPM]":"5.6","Cell RNA - RPMI-8226 [nTPM]":"24.1","Cell RNA - RPTEC TERT1 [nTPM]":"18.4","Cell RNA - RT4 [nTPM]":"12.4","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"6.2","Cell RNA - SiHa [nTPM]":"8.1","Cell RNA - SK-BR-3 [nTPM]":"12.2","Cell RNA - SK-MEL-30 [nTPM]":"17.3","Cell RNA - SuSa [nTPM]":"5.4","Cell RNA - T-47d [nTPM]":"11.7","Cell RNA - THP-1 [nTPM]":"22.2","Cell RNA - TIME [nTPM]":"9.5","Cell RNA - U-138 MG [nTPM]":"13.6","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"3.7","Cell RNA - U-251 MG [nTPM]":"18.6","Cell RNA - U-266\/70 [nTPM]":"8.1","Cell RNA - U-266\/84 [nTPM]":"15.9","Cell RNA - U-698 [nTPM]":"8.6","Cell RNA - U-87 MG [nTPM]":"12.4","Cell RNA - U-937 [nTPM]":"34.5","Cell RNA - WM-115 [nTPM]":"10.2","Blood RNA - basophil [nTPM]":"13.6","Blood RNA - classical monocyte [nTPM]":"7.7","Blood RNA - eosinophil [nTPM]":"3.3","Blood RNA - gdT-cell [nTPM]":"6.2","Blood RNA - intermediate monocyte [nTPM]":"9.7","Blood RNA - MAIT T-cell [nTPM]":"7.0","Blood RNA - memory B-cell [nTPM]":"6.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.9","Blood RNA - myeloid DC [nTPM]":"7.0","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.8","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"14.5","Blood RNA - NK-cell [nTPM]":"5.3","Blood RNA - non-classical monocyte [nTPM]":"11.4","Blood RNA - plasmacytoid DC [nTPM]":"5.4","Blood RNA - T-reg [nTPM]":"6.5","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.6","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"3.1","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.5","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"27.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"14.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"26.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.6","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.4","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"4.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"4.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"6.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"8.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"2.7","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.9","Single Cell Type RNA - Paneth cells [nTPM]":"4.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.9","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"12.5","Single Cell Type RNA - Theca cells [nTPM]":"4.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.0","Single Cell Type RNA - Urothelial cells [nTPM]":"7.4"},{"Gene":"PIGP","Gene synonym":["DCRC","DSCR5","DSRC"],"Ensembl":"ENSG00000185808","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class P","Uniprot":["P57054"],"Chromosome":"21","Position":"37062846-37073170","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"350.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026921"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA026921":"AB_1847874"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"33.9","Tissue RNA - adrenal gland [nTPM]":"41.3","Tissue RNA - amygdala [nTPM]":"18.7","Tissue RNA - appendix [nTPM]":"12.5","Tissue RNA - basal ganglia [nTPM]":"20.2","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"35.4","Tissue RNA - cerebellum [nTPM]":"22.4","Tissue RNA - cerebral cortex [nTPM]":"24.7","Tissue RNA - cervix [nTPM]":"22.9","Tissue RNA - choroid plexus [nTPM]":"24.8","Tissue RNA - colon [nTPM]":"24.2","Tissue RNA - duodenum [nTPM]":"19.0","Tissue RNA - endometrium 1 [nTPM]":"18.3","Tissue RNA - epididymis [nTPM]":"107.2","Tissue RNA - esophagus [nTPM]":"16.8","Tissue RNA - fallopian tube [nTPM]":"25.7","Tissue RNA - gallbladder [nTPM]":"22.5","Tissue RNA - heart muscle [nTPM]":"40.1","Tissue RNA - hippocampal formation [nTPM]":"18.1","Tissue RNA - hypothalamus [nTPM]":"22.8","Tissue RNA - kidney [nTPM]":"35.9","Tissue RNA - liver [nTPM]":"54.7","Tissue RNA - lung [nTPM]":"21.6","Tissue RNA - lymph node [nTPM]":"16.6","Tissue RNA - medulla oblongata [nTPM]":"22.8","Tissue RNA - midbrain [nTPM]":"21.6","Tissue RNA - ovary [nTPM]":"27.9","Tissue RNA - pancreas [nTPM]":"41.4","Tissue RNA - parathyroid gland [nTPM]":"51.9","Tissue RNA - pituitary gland [nTPM]":"38.0","Tissue RNA - placenta [nTPM]":"20.9","Tissue RNA - pons [nTPM]":"22.6","Tissue RNA - prostate [nTPM]":"33.7","Tissue RNA - rectum [nTPM]":"27.4","Tissue RNA - retina [nTPM]":"28.6","Tissue RNA - salivary gland [nTPM]":"32.2","Tissue RNA - seminal vesicle [nTPM]":"26.7","Tissue RNA - skeletal muscle [nTPM]":"44.0","Tissue RNA - skin 1 [nTPM]":"12.4","Tissue RNA - small intestine [nTPM]":"15.5","Tissue RNA - smooth muscle [nTPM]":"17.1","Tissue RNA - spinal cord [nTPM]":"22.1","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"22.8","Tissue RNA - testis [nTPM]":"36.5","Tissue RNA - thalamus [nTPM]":"20.0","Tissue RNA - thymus [nTPM]":"22.0","Tissue RNA - thyroid gland [nTPM]":"36.3","Tissue RNA - tongue [nTPM]":"42.8","Tissue RNA - tonsil [nTPM]":"19.7","Tissue RNA - urinary bladder [nTPM]":"26.2","Tissue RNA - vagina [nTPM]":"13.2","Tissue RNA - white matter [nTPM]":"25.4","Cell RNA - A-431 [nTPM]":"25.9","Cell RNA - A549 [nTPM]":"11.5","Cell RNA - AF22 [nTPM]":"23.7","Cell RNA - AN3-CA [nTPM]":"14.8","Cell RNA - ASC diff [nTPM]":"41.5","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"16.9","Cell RNA - BJ [nTPM]":"21.9","Cell RNA - BJ hTERT+ [nTPM]":"38.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.1","Cell RNA - CACO-2 [nTPM]":"15.4","Cell RNA - CAPAN-2 [nTPM]":"53.7","Cell RNA - Daudi [nTPM]":"37.1","Cell RNA - EFO-21 [nTPM]":"45.7","Cell RNA - fHDF\/TERT166 [nTPM]":"32.0","Cell RNA - GAMG [nTPM]":"81.4","Cell RNA - HaCaT [nTPM]":"19.4","Cell RNA - HAP1 [nTPM]":"22.7","Cell RNA - HBEC3-KT [nTPM]":"25.5","Cell RNA - HBF TERT88 [nTPM]":"18.5","Cell RNA - HDLM-2 [nTPM]":"37.4","Cell RNA - HEK 293 [nTPM]":"36.1","Cell RNA - HEL [nTPM]":"86.2","Cell RNA - HeLa [nTPM]":"13.8","Cell RNA - Hep G2 [nTPM]":"21.3","Cell RNA - HHSteC [nTPM]":"26.3","Cell RNA - HL-60 [nTPM]":"26.9","Cell RNA - HMC-1 [nTPM]":"16.6","Cell RNA - HSkMC [nTPM]":"26.5","Cell RNA - hTCEpi [nTPM]":"47.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.4","Cell RNA - hTERT-HME1 [nTPM]":"43.0","Cell RNA - hTERT-RPE1 [nTPM]":"42.2","Cell RNA - HUVEC TERT2 [nTPM]":"35.1","Cell RNA - JURKAT [nTPM]":"80.5","Cell RNA - K-562 [nTPM]":"50.7","Cell RNA - Karpas-707 [nTPM]":"61.8","Cell RNA - LHCN-M2 [nTPM]":"38.5","Cell RNA - MCF7 [nTPM]":"16.5","Cell RNA - MOLT-4 [nTPM]":"32.9","Cell RNA - NB-4 [nTPM]":"25.5","Cell RNA - NTERA-2 [nTPM]":"19.6","Cell RNA - OE19 [nTPM]":"76.8","Cell RNA - PC-3 [nTPM]":"27.9","Cell RNA - REH [nTPM]":"31.0","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"37.0","Cell RNA - RPTEC TERT1 [nTPM]":"48.2","Cell RNA - RT4 [nTPM]":"13.3","Cell RNA - SCLC-21H [nTPM]":"49.2","Cell RNA - SH-SY5Y [nTPM]":"29.8","Cell RNA - SiHa [nTPM]":"61.4","Cell RNA - SK-BR-3 [nTPM]":"43.0","Cell RNA - SK-MEL-30 [nTPM]":"81.8","Cell RNA - SuSa [nTPM]":"33.6","Cell RNA - T-47d [nTPM]":"35.2","Cell RNA - THP-1 [nTPM]":"53.2","Cell RNA - TIME [nTPM]":"18.3","Cell RNA - U-138 MG [nTPM]":"12.9","Cell RNA - U-2 OS [nTPM]":"6.6","Cell RNA - U-2197 [nTPM]":"14.8","Cell RNA - U-251 MG [nTPM]":"19.3","Cell RNA - U-266\/70 [nTPM]":"81.1","Cell RNA - U-266\/84 [nTPM]":"96.5","Cell RNA - U-698 [nTPM]":"42.0","Cell RNA - U-87 MG [nTPM]":"38.1","Cell RNA - U-937 [nTPM]":"30.5","Cell RNA - WM-115 [nTPM]":"43.4","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"13.5","Blood RNA - eosinophil [nTPM]":"3.7","Blood RNA - gdT-cell [nTPM]":"19.6","Blood RNA - intermediate monocyte [nTPM]":"20.3","Blood RNA - MAIT T-cell [nTPM]":"24.8","Blood RNA - memory B-cell [nTPM]":"34.2","Blood RNA - memory CD4 T-cell [nTPM]":"25.1","Blood RNA - memory CD8 T-cell [nTPM]":"21.6","Blood RNA - myeloid DC [nTPM]":"20.9","Blood RNA - naive B-cell [nTPM]":"28.1","Blood RNA - naive CD4 T-cell [nTPM]":"33.3","Blood RNA - naive CD8 T-cell [nTPM]":"29.0","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"16.8","Blood RNA - non-classical monocyte [nTPM]":"22.6","Blood RNA - plasmacytoid DC [nTPM]":"30.9","Blood RNA - T-reg [nTPM]":"20.6","Blood RNA - total PBMC [nTPM]":"15.6","Brain RNA - amygdala [nTPM]":"18.7","Brain RNA - basal ganglia [nTPM]":"20.2","Brain RNA - cerebellum [nTPM]":"22.4","Brain RNA - cerebral cortex [nTPM]":"24.7","Brain RNA - hippocampal formation [nTPM]":"18.1","Brain RNA - hypothalamus [nTPM]":"22.8","Brain RNA - medulla oblongata [nTPM]":"22.8","Brain RNA - midbrain [nTPM]":"21.6","Brain RNA - pons [nTPM]":"22.6","Brain RNA - spinal cord [nTPM]":"22.1","Brain RNA - thalamus [nTPM]":"20.0","Brain RNA - white matter [nTPM]":"25.4","Single Cell Type RNA - Adipocytes [nTPM]":"37.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"41.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"37.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"58.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"88.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.3","Single Cell Type RNA - Bipolar cells [nTPM]":"21.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"74.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"86.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"82.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"65.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"60.7","Single Cell Type RNA - dendritic cells [nTPM]":"29.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"90.1","Single Cell Type RNA - Ductal cells [nTPM]":"61.8","Single Cell Type RNA - Early spermatids [nTPM]":"79.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.9","Single Cell Type RNA - Endothelial cells [nTPM]":"31.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.9","Single Cell Type RNA - Erythroid cells [nTPM]":"25.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"52.4","Single Cell Type RNA - Fibroblasts [nTPM]":"48.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.3","Single Cell Type RNA - granulocytes [nTPM]":"15.9","Single Cell Type RNA - Granulosa cells [nTPM]":"32.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.3","Single Cell Type RNA - Hepatocytes [nTPM]":"79.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"66.7","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"63.9","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"57.6","Single Cell Type RNA - Langerhans cells [nTPM]":"39.9","Single Cell Type RNA - Late spermatids [nTPM]":"75.6","Single Cell Type RNA - Leydig cells [nTPM]":"69.0","Single Cell Type RNA - Macrophages [nTPM]":"44.1","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"50.2","Single Cell Type RNA - Muller glia cells [nTPM]":"37.0","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"57.7","Single Cell Type RNA - Paneth cells [nTPM]":"50.3","Single Cell Type RNA - Peritubular cells [nTPM]":"35.0","Single Cell Type RNA - Plasma cells [nTPM]":"54.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"52.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"97.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"86.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.6","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.6","Single Cell Type RNA - Spermatocytes [nTPM]":"350.8","Single Cell Type RNA - Spermatogonia [nTPM]":"177.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"44.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.3","Single Cell Type RNA - T-cells [nTPM]":"31.7","Single Cell Type RNA - Theca cells [nTPM]":"62.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"53.1","Single Cell Type RNA - Urothelial cells [nTPM]":"63.7"},{"Gene":"PIGQ","Gene synonym":["GPI1","hGPI1"],"Ensembl":"ENSG00000007541","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class Q","Uniprot":["Q9BRB3"],"Chromosome":"16","Position":"566995-584109","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"78.9","Late spermatids":"61.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039105","HPA039828","HPA061414"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA039105":"AB_10796221","HPA039828":"AB_10795158","HPA061414":"AB_2684508"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.3","Tissue RNA - adrenal gland [nTPM]":"23.9","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"30.4","Tissue RNA - breast [nTPM]":"15.0","Tissue RNA - cerebellum [nTPM]":"2.0","Tissue RNA - cerebral cortex [nTPM]":"12.0","Tissue RNA - cervix [nTPM]":"15.4","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"16.2","Tissue RNA - duodenum [nTPM]":"7.5","Tissue RNA - endometrium 1 [nTPM]":"18.3","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"13.2","Tissue RNA - fallopian tube [nTPM]":"16.5","Tissue RNA - gallbladder [nTPM]":"2.8","Tissue RNA - heart muscle [nTPM]":"13.3","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"30.7","Tissue RNA - liver [nTPM]":"19.0","Tissue RNA - lung [nTPM]":"17.9","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"6.6","Tissue RNA - midbrain [nTPM]":"9.7","Tissue RNA - ovary [nTPM]":"15.6","Tissue RNA - pancreas [nTPM]":"21.9","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"25.4","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"19.4","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"19.3","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"15.7","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"15.0","Tissue RNA - stomach 1 [nTPM]":"17.0","Tissue RNA - testis [nTPM]":"28.1","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"31.1","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"15.8","Tissue RNA - vagina [nTPM]":"12.1","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"14.2","Cell RNA - A549 [nTPM]":"21.9","Cell RNA - AF22 [nTPM]":"7.3","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"4.6","Cell RNA - ASC TERT1 [nTPM]":"2.7","Cell RNA - BEWO [nTPM]":"13.9","Cell RNA - BJ [nTPM]":"14.7","Cell RNA - BJ hTERT+ [nTPM]":"5.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.6","Cell RNA - CACO-2 [nTPM]":"14.6","Cell RNA - CAPAN-2 [nTPM]":"12.9","Cell RNA - Daudi [nTPM]":"7.6","Cell RNA - EFO-21 [nTPM]":"18.6","Cell RNA - fHDF\/TERT166 [nTPM]":"3.3","Cell RNA - GAMG [nTPM]":"5.5","Cell RNA - HaCaT [nTPM]":"22.2","Cell RNA - HAP1 [nTPM]":"3.3","Cell RNA - HBEC3-KT [nTPM]":"6.4","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"21.9","Cell RNA - HEK 293 [nTPM]":"30.4","Cell RNA - HEL [nTPM]":"11.4","Cell RNA - HeLa [nTPM]":"23.8","Cell RNA - Hep G2 [nTPM]":"10.8","Cell RNA - HHSteC [nTPM]":"8.9","Cell RNA - HL-60 [nTPM]":"10.1","Cell RNA - HMC-1 [nTPM]":"10.2","Cell RNA - HSkMC [nTPM]":"5.2","Cell RNA - hTCEpi [nTPM]":"9.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.2","Cell RNA - hTERT-HME1 [nTPM]":"2.0","Cell RNA - hTERT-RPE1 [nTPM]":"4.0","Cell RNA - HUVEC TERT2 [nTPM]":"6.1","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"26.1","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"20.7","Cell RNA - MOLT-4 [nTPM]":"18.3","Cell RNA - NB-4 [nTPM]":"11.4","Cell RNA - NTERA-2 [nTPM]":"10.0","Cell RNA - OE19 [nTPM]":"3.0","Cell RNA - PC-3 [nTPM]":"21.9","Cell RNA - REH [nTPM]":"36.6","Cell RNA - RH-30 [nTPM]":"6.4","Cell RNA - RPMI-8226 [nTPM]":"17.7","Cell RNA - RPTEC TERT1 [nTPM]":"5.6","Cell RNA - RT4 [nTPM]":"5.6","Cell RNA - SCLC-21H [nTPM]":"13.2","Cell RNA - SH-SY5Y [nTPM]":"21.4","Cell RNA - SiHa [nTPM]":"16.8","Cell RNA - SK-BR-3 [nTPM]":"7.6","Cell RNA - SK-MEL-30 [nTPM]":"10.8","Cell RNA - SuSa [nTPM]":"2.3","Cell RNA - T-47d [nTPM]":"17.3","Cell RNA - THP-1 [nTPM]":"6.9","Cell RNA - TIME [nTPM]":"14.5","Cell RNA - U-138 MG [nTPM]":"10.4","Cell RNA - U-2 OS [nTPM]":"13.7","Cell RNA - U-2197 [nTPM]":"11.7","Cell RNA - U-251 MG [nTPM]":"10.4","Cell RNA - U-266\/70 [nTPM]":"15.8","Cell RNA - U-266\/84 [nTPM]":"5.0","Cell RNA - U-698 [nTPM]":"6.0","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"5.4","Cell RNA - WM-115 [nTPM]":"10.4","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"2.8","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"3.7","Blood RNA - plasmacytoid DC [nTPM]":"5.6","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"2.0","Brain RNA - cerebral cortex [nTPM]":"12.0","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"6.6","Brain RNA - midbrain [nTPM]":"9.7","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"9.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.3","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"6.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"10.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.5","Single Cell Type RNA - dendritic cells [nTPM]":"8.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"33.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"9.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"78.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.4","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.4","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"19.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"16.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.5","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.1","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"61.4","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"8.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"7.7","Single Cell Type RNA - Muller glia cells [nTPM]":"14.6","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.1","Single Cell Type RNA - Paneth cells [nTPM]":"11.6","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.9","Single Cell Type RNA - Spermatocytes [nTPM]":"30.1","Single Cell Type RNA - Spermatogonia [nTPM]":"13.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"7.8","Single Cell Type RNA - Theca cells [nTPM]":"11.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.9","Single Cell Type RNA - Urothelial cells [nTPM]":"5.0"},{"Gene":"PIK3R5","Gene synonym":["p101","P101-PI3K"],"Ensembl":"ENSG00000141506","Gene description":"Phosphoinositide-3-kinase regulatory subunit 5","Uniprot":["Q8WYR1"],"Chromosome":"17","Position":"8878911-8965712","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"87.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"29.9","Kupffer cells":"35.7","Langerhans cells":"40.5","Macrophages":"36.8","Microglial cells":"79.6","NK-cells":"32.0","Plasma cells":"24.7","T-cells":"25.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"39.2","HMC-1":"5.7","JURKAT":"13.7","U-937":"11.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044505","HPA052247","HPA052412"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA044505":"AB_2678964","HPA052247":"AB_2681772","HPA052412":"AB_2681823"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.5","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"19.7","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"87.4","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"3.3","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"2.5","Tissue RNA - fallopian tube [nTPM]":"3.0","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"14.1","Tissue RNA - lymph node [nTPM]":"13.7","Tissue RNA - medulla oblongata [nTPM]":"4.0","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.1","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"1.5","Tissue RNA - small intestine [nTPM]":"9.5","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"22.4","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"3.4","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"39.2","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"1.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"5.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"4.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"5.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"11.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"9.5","Blood RNA - classical monocyte [nTPM]":"16.1","Blood RNA - eosinophil [nTPM]":"5.7","Blood RNA - gdT-cell [nTPM]":"18.1","Blood RNA - intermediate monocyte [nTPM]":"14.3","Blood RNA - MAIT T-cell [nTPM]":"11.8","Blood RNA - memory B-cell [nTPM]":"4.3","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"15.6","Blood RNA - myeloid DC [nTPM]":"11.5","Blood RNA - naive B-cell [nTPM]":"5.7","Blood RNA - naive CD4 T-cell [nTPM]":"7.5","Blood RNA - naive CD8 T-cell [nTPM]":"12.0","Blood RNA - neutrophil [nTPM]":"34.4","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"19.0","Blood RNA - plasmacytoid DC [nTPM]":"9.0","Blood RNA - T-reg [nTPM]":"13.2","Blood RNA - total PBMC [nTPM]":"16.2","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"4.0","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"11.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"29.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"35.7","Single Cell Type RNA - Langerhans cells [nTPM]":"40.5","Single Cell Type RNA - Late spermatids [nTPM]":"12.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"36.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"79.6","Single Cell Type RNA - monocytes [nTPM]":"19.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"24.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"25.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PIKFYVE","Gene synonym":["FAB1","KIAA0981","MGC40423","p235","PIP5K","PIP5K3","ZFYVE29"],"Ensembl":"ENSG00000115020","Gene description":"Phosphoinositide kinase, FYVE-type zinc finger containing","Uniprot":["Q9Y2I7"],"Chromosome":"2","Position":"208266255-208358746","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"82.0","Oligodendrocyte precursor cells":"80.9","Oligodendrocytes":"81.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042604"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042604":"AB_10796580"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.81e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.4","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"7.6","Tissue RNA - appendix [nTPM]":"12.0","Tissue RNA - basal ganglia [nTPM]":"7.6","Tissue RNA - bone marrow [nTPM]":"28.8","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"14.3","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"10.5","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"11.9","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"7.2","Tissue RNA - heart muscle [nTPM]":"7.4","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"10.6","Tissue RNA - liver [nTPM]":"10.5","Tissue RNA - lung [nTPM]":"7.8","Tissue RNA - lymph node [nTPM]":"17.4","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"10.0","Tissue RNA - pancreas [nTPM]":"22.2","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"9.7","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"11.5","Tissue RNA - rectum [nTPM]":"7.4","Tissue RNA - retina [nTPM]":"17.3","Tissue RNA - salivary gland [nTPM]":"6.5","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"6.5","Tissue RNA - skin 1 [nTPM]":"8.2","Tissue RNA - small intestine [nTPM]":"7.3","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"7.4","Tissue RNA - spleen [nTPM]":"15.1","Tissue RNA - stomach 1 [nTPM]":"8.0","Tissue RNA - testis [nTPM]":"14.0","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"19.3","Tissue RNA - thyroid gland [nTPM]":"12.2","Tissue RNA - tongue [nTPM]":"9.0","Tissue RNA - tonsil [nTPM]":"16.1","Tissue RNA - urinary bladder [nTPM]":"8.2","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"11.1","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"18.3","Cell RNA - AN3-CA [nTPM]":"14.3","Cell RNA - ASC diff [nTPM]":"18.1","Cell RNA - ASC TERT1 [nTPM]":"21.4","Cell RNA - BEWO [nTPM]":"8.5","Cell RNA - BJ [nTPM]":"9.6","Cell RNA - BJ hTERT+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.0","Cell RNA - CACO-2 [nTPM]":"11.3","Cell RNA - CAPAN-2 [nTPM]":"6.6","Cell RNA - Daudi [nTPM]":"9.2","Cell RNA - EFO-21 [nTPM]":"9.8","Cell RNA - fHDF\/TERT166 [nTPM]":"16.6","Cell RNA - GAMG [nTPM]":"21.7","Cell RNA - HaCaT [nTPM]":"8.0","Cell RNA - HAP1 [nTPM]":"16.1","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"18.8","Cell RNA - HDLM-2 [nTPM]":"7.9","Cell RNA - HEK 293 [nTPM]":"10.1","Cell RNA - HEL [nTPM]":"33.0","Cell RNA - HeLa [nTPM]":"15.6","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"13.7","Cell RNA - HL-60 [nTPM]":"29.5","Cell RNA - HMC-1 [nTPM]":"28.5","Cell RNA - HSkMC [nTPM]":"16.0","Cell RNA - hTCEpi [nTPM]":"11.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.0","Cell RNA - hTERT-HME1 [nTPM]":"24.1","Cell RNA - hTERT-RPE1 [nTPM]":"18.5","Cell RNA - HUVEC TERT2 [nTPM]":"18.3","Cell RNA - JURKAT [nTPM]":"24.1","Cell RNA - K-562 [nTPM]":"22.7","Cell RNA - Karpas-707 [nTPM]":"16.1","Cell RNA - LHCN-M2 [nTPM]":"14.0","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"26.9","Cell RNA - NB-4 [nTPM]":"22.1","Cell RNA - NTERA-2 [nTPM]":"15.2","Cell RNA - OE19 [nTPM]":"6.1","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"14.2","Cell RNA - RPMI-8226 [nTPM]":"12.7","Cell RNA - RPTEC TERT1 [nTPM]":"14.2","Cell RNA - RT4 [nTPM]":"11.5","Cell RNA - SCLC-21H [nTPM]":"5.8","Cell RNA - SH-SY5Y [nTPM]":"13.8","Cell RNA - SiHa [nTPM]":"10.6","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"19.2","Cell RNA - SuSa [nTPM]":"21.4","Cell RNA - T-47d [nTPM]":"4.3","Cell RNA - THP-1 [nTPM]":"31.3","Cell RNA - TIME [nTPM]":"21.2","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"9.4","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"11.2","Cell RNA - U-266\/84 [nTPM]":"14.2","Cell RNA - U-698 [nTPM]":"19.2","Cell RNA - U-87 MG [nTPM]":"11.1","Cell RNA - U-937 [nTPM]":"25.2","Cell RNA - WM-115 [nTPM]":"13.9","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"7.6","Brain RNA - basal ganglia [nTPM]":"7.6","Brain RNA - cerebellum [nTPM]":"14.3","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"7.4","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"11.1","Single Cell Type RNA - Adipocytes [nTPM]":"18.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.2","Single Cell Type RNA - Astrocytes [nTPM]":"58.8","Single Cell Type RNA - B-cells [nTPM]":"82.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"21.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"10.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"14.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.4","Single Cell Type RNA - Endothelial cells [nTPM]":"18.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.6","Single Cell Type RNA - Erythroid cells [nTPM]":"25.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"72.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.7","Single Cell Type RNA - granulocytes [nTPM]":"36.1","Single Cell Type RNA - Granulosa cells [nTPM]":"18.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"19.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.4","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"67.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"29.9","Single Cell Type RNA - Langerhans cells [nTPM]":"32.5","Single Cell Type RNA - Late spermatids [nTPM]":"8.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"28.5","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"48.7","Single Cell Type RNA - monocytes [nTPM]":"19.1","Single Cell Type RNA - Muller glia cells [nTPM]":"13.5","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"80.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"81.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.5","Single Cell Type RNA - Paneth cells [nTPM]":"5.9","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"10.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.9","Single Cell Type RNA - Spermatocytes [nTPM]":"30.5","Single Cell Type RNA - Spermatogonia [nTPM]":"23.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"21.5","Single Cell Type RNA - Theca cells [nTPM]":"13.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.8","Single Cell Type RNA - Urothelial cells [nTPM]":"11.4"},{"Gene":"PINK1","Gene synonym":["BRPK","PARK6"],"Ensembl":"ENSG00000158828","Gene description":"PTEN induced kinase 1","Uniprot":["Q9BXM7"],"Chromosome":"1","Position":"20633458-20651511","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"384.4","tongue":"392.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"151.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"8.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001931","CAB026191"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026191":null,"HPA001931":"AB_1079620"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Tissue RNA - adipose tissue [nTPM]":"50.7","Tissue RNA - adrenal gland [nTPM]":"127.2","Tissue RNA - amygdala [nTPM]":"119.3","Tissue RNA - appendix [nTPM]":"13.7","Tissue RNA - basal ganglia [nTPM]":"103.4","Tissue RNA - bone marrow [nTPM]":"13.0","Tissue RNA - breast [nTPM]":"41.9","Tissue RNA - cerebellum [nTPM]":"104.6","Tissue RNA - cerebral cortex [nTPM]":"110.9","Tissue RNA - cervix [nTPM]":"37.9","Tissue RNA - choroid plexus [nTPM]":"73.0","Tissue RNA - colon [nTPM]":"62.3","Tissue RNA - duodenum [nTPM]":"32.3","Tissue RNA - endometrium 1 [nTPM]":"43.9","Tissue RNA - epididymis [nTPM]":"18.8","Tissue RNA - esophagus [nTPM]":"48.8","Tissue RNA - fallopian tube [nTPM]":"34.4","Tissue RNA - gallbladder [nTPM]":"23.5","Tissue RNA - heart muscle [nTPM]":"153.4","Tissue RNA - hippocampal formation [nTPM]":"106.6","Tissue RNA - hypothalamus [nTPM]":"107.0","Tissue RNA - kidney [nTPM]":"56.8","Tissue RNA - liver [nTPM]":"76.8","Tissue RNA - lung [nTPM]":"30.1","Tissue RNA - lymph node [nTPM]":"10.8","Tissue RNA - medulla oblongata [nTPM]":"118.5","Tissue RNA - midbrain [nTPM]":"127.8","Tissue RNA - ovary [nTPM]":"30.1","Tissue RNA - pancreas [nTPM]":"52.7","Tissue RNA - parathyroid gland [nTPM]":"66.5","Tissue RNA - pituitary gland [nTPM]":"33.4","Tissue RNA - placenta [nTPM]":"21.3","Tissue RNA - pons [nTPM]":"118.3","Tissue RNA - prostate [nTPM]":"37.1","Tissue RNA - rectum [nTPM]":"15.0","Tissue RNA - retina [nTPM]":"29.4","Tissue RNA - salivary gland [nTPM]":"55.0","Tissue RNA - seminal vesicle [nTPM]":"29.7","Tissue RNA - skeletal muscle [nTPM]":"384.4","Tissue RNA - skin 1 [nTPM]":"55.3","Tissue RNA - small intestine [nTPM]":"35.2","Tissue RNA - smooth muscle [nTPM]":"20.0","Tissue RNA - spinal cord [nTPM]":"124.9","Tissue RNA - spleen [nTPM]":"27.9","Tissue RNA - stomach 1 [nTPM]":"46.7","Tissue RNA - testis [nTPM]":"94.8","Tissue RNA - thalamus [nTPM]":"132.1","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"41.6","Tissue RNA - tongue [nTPM]":"392.3","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"47.4","Tissue RNA - vagina [nTPM]":"42.7","Tissue RNA - white matter [nTPM]":"95.0","Cell RNA - A-431 [nTPM]":"49.9","Cell RNA - A549 [nTPM]":"22.2","Cell RNA - AF22 [nTPM]":"10.3","Cell RNA - AN3-CA [nTPM]":"29.6","Cell RNA - ASC diff [nTPM]":"34.6","Cell RNA - ASC TERT1 [nTPM]":"32.8","Cell RNA - BEWO [nTPM]":"10.7","Cell RNA - BJ [nTPM]":"68.2","Cell RNA - BJ hTERT+ [nTPM]":"67.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.1","Cell RNA - CACO-2 [nTPM]":"7.7","Cell RNA - CAPAN-2 [nTPM]":"39.3","Cell RNA - Daudi [nTPM]":"11.7","Cell RNA - EFO-21 [nTPM]":"52.6","Cell RNA - fHDF\/TERT166 [nTPM]":"69.9","Cell RNA - GAMG [nTPM]":"75.4","Cell RNA - HaCaT [nTPM]":"22.5","Cell RNA - HAP1 [nTPM]":"15.0","Cell RNA - HBEC3-KT [nTPM]":"36.2","Cell RNA - HBF TERT88 [nTPM]":"16.0","Cell RNA - HDLM-2 [nTPM]":"14.0","Cell RNA - HEK 293 [nTPM]":"56.8","Cell RNA - HEL [nTPM]":"5.9","Cell RNA - HeLa [nTPM]":"60.3","Cell RNA - Hep G2 [nTPM]":"12.1","Cell RNA - HHSteC [nTPM]":"26.8","Cell RNA - HL-60 [nTPM]":"6.3","Cell RNA - HMC-1 [nTPM]":"17.7","Cell RNA - HSkMC [nTPM]":"30.8","Cell RNA - hTCEpi [nTPM]":"38.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.6","Cell RNA - hTERT-HME1 [nTPM]":"13.9","Cell RNA - hTERT-RPE1 [nTPM]":"36.2","Cell RNA - HUVEC TERT2 [nTPM]":"21.3","Cell RNA - JURKAT [nTPM]":"10.7","Cell RNA - K-562 [nTPM]":"14.5","Cell RNA - Karpas-707 [nTPM]":"14.5","Cell RNA - LHCN-M2 [nTPM]":"23.6","Cell RNA - MCF7 [nTPM]":"21.2","Cell RNA - MOLT-4 [nTPM]":"9.2","Cell RNA - NB-4 [nTPM]":"14.1","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"12.9","Cell RNA - PC-3 [nTPM]":"72.2","Cell RNA - REH [nTPM]":"7.9","Cell RNA - RH-30 [nTPM]":"18.0","Cell RNA - RPMI-8226 [nTPM]":"9.4","Cell RNA - RPTEC TERT1 [nTPM]":"20.1","Cell RNA - RT4 [nTPM]":"11.5","Cell RNA - SCLC-21H [nTPM]":"37.8","Cell RNA - SH-SY5Y [nTPM]":"14.8","Cell RNA - SiHa [nTPM]":"74.4","Cell RNA - SK-BR-3 [nTPM]":"24.2","Cell RNA - SK-MEL-30 [nTPM]":"20.8","Cell RNA - SuSa [nTPM]":"12.3","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"21.6","Cell RNA - TIME [nTPM]":"32.6","Cell RNA - U-138 MG [nTPM]":"29.1","Cell RNA - U-2 OS [nTPM]":"14.9","Cell RNA - U-2197 [nTPM]":"49.2","Cell RNA - U-251 MG [nTPM]":"9.7","Cell RNA - U-266\/70 [nTPM]":"16.7","Cell RNA - U-266\/84 [nTPM]":"3.6","Cell RNA - U-698 [nTPM]":"5.4","Cell RNA - U-87 MG [nTPM]":"63.1","Cell RNA - U-937 [nTPM]":"17.9","Cell RNA - WM-115 [nTPM]":"14.0","Blood RNA - basophil [nTPM]":"3.6","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"3.7","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"119.3","Brain RNA - basal ganglia [nTPM]":"103.4","Brain RNA - cerebellum [nTPM]":"104.6","Brain RNA - cerebral cortex [nTPM]":"110.9","Brain RNA - hippocampal formation [nTPM]":"106.6","Brain RNA - hypothalamus [nTPM]":"107.0","Brain RNA - medulla oblongata [nTPM]":"118.5","Brain RNA - midbrain [nTPM]":"127.8","Brain RNA - pons [nTPM]":"118.3","Brain RNA - spinal cord [nTPM]":"124.9","Brain RNA - thalamus [nTPM]":"132.1","Brain RNA - white matter [nTPM]":"95.0","Single Cell Type RNA - Adipocytes [nTPM]":"38.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.2","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"50.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.3","Single Cell Type RNA - dendritic cells [nTPM]":"9.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"107.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"80.3","Single Cell Type RNA - Ductal cells [nTPM]":"24.0","Single Cell Type RNA - Early spermatids [nTPM]":"77.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.1","Single Cell Type RNA - Endothelial cells [nTPM]":"48.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.0","Single Cell Type RNA - Erythroid cells [nTPM]":"56.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.8","Single Cell Type RNA - Fibroblasts [nTPM]":"27.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"36.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"84.3","Single Cell Type RNA - Hepatocytes [nTPM]":"110.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.7","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"27.1","Single Cell Type RNA - Langerhans cells [nTPM]":"16.3","Single Cell Type RNA - Late spermatids [nTPM]":"151.4","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"22.7","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"10.1","Single Cell Type RNA - Muller glia cells [nTPM]":"69.7","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"56.6","Single Cell Type RNA - Paneth cells [nTPM]":"67.9","Single Cell Type RNA - Peritubular cells [nTPM]":"56.8","Single Cell Type RNA - Plasma cells [nTPM]":"27.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"67.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"109.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.0","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.2","Single Cell Type RNA - Spermatocytes [nTPM]":"120.8","Single Cell Type RNA - Spermatogonia [nTPM]":"24.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - T-cells [nTPM]":"10.6","Single Cell Type RNA - Theca cells [nTPM]":"34.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.4","Single Cell Type RNA - Urothelial cells [nTPM]":"47.9"},{"Gene":"PITPNM3","Gene synonym":["ACKR6","CORD5","NIR1","RDGBA3"],"Ensembl":"ENSG00000091622","Gene description":"PITPNM family member 3","Uniprot":["Q9BZ71"],"Chromosome":"17","Position":"6451263-6556555","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"60.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"20.5","Hepatic stellate cells":"27.8","Inhibitory neurons":"24.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"23","RNA blood cell specific nTPM":{"neutrophil":"2.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"granulocytes":"2.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"17.7","HeLa":"14.8","hTCEpi":"50.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022432","HPA059005"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA022432":"AB_2670936","HPA059005":"AB_2683876"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.67e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"23.6","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"20.7","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"23.7","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"17.8","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"19.1","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"1.4","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"26.6","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"2.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"4.5","Tissue RNA - rectum [nTPM]":"3.7","Tissue RNA - retina [nTPM]":"7.9","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"17.0","Tissue RNA - small intestine [nTPM]":"2.7","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"60.8","Tissue RNA - stomach 1 [nTPM]":"6.8","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"13.0","Cell RNA - A-431 [nTPM]":"9.0","Cell RNA - A549 [nTPM]":"0.9","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"6.3","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"2.4","Cell RNA - HaCaT [nTPM]":"17.7","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"3.7","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"14.8","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"50.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.0","Cell RNA - hTERT-HME1 [nTPM]":"2.8","Cell RNA - hTERT-RPE1 [nTPM]":"4.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"1.0","Cell RNA - OE19 [nTPM]":"4.5","Cell RNA - PC-3 [nTPM]":"2.5","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.2","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"8.1","Cell RNA - SK-BR-3 [nTPM]":"3.8","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"1.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"2.1","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"23.6","Brain RNA - basal ganglia [nTPM]":"20.7","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"23.7","Brain RNA - hippocampal formation [nTPM]":"19.1","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"13.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"13.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"11.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"1.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.0","Single Cell Type RNA - Paneth cells [nTPM]":"5.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.9","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"7.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.5","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"PITX2","Gene synonym":["ARP1","Brx1","IGDS","IHG2","IRID2","Otlx2","RGS","RIEG","RIEG1","RS"],"Ensembl":"ENSG00000164093","Gene description":"Paired like homeodomain 2","Uniprot":["Q99697"],"Chromosome":"4","Position":"110617423-110642123","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Disease variant","Peters anomaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"42.0","skeletal muscle":"43.2","urinary bladder":"29.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"19.2","Fibroblasts":"69.6","Paneth cells":"20.6","Proximal enterocytes":"39.7","Skeletal myocytes":"49.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"hypothalamus":"17.8","thalamus":"6.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"24.8","HEK 293":"10.5","LHCN-M2":"25.1","RH-30":"20.5"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"25","RNA pig brain regional specific nTPM":{"hypothalamus":"5.4","midbrain":"1.5"},"Antibody":["HPA050074","HPA062728"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA050074":"AB_2681005","HPA062728":"AB_2684851"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.8","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.6","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"2.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"16.1","Tissue RNA - placenta [nTPM]":"42.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"13.5","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"43.2","Tissue RNA - skin 1 [nTPM]":"1.5","Tissue RNA - small intestine [nTPM]":"3.1","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"12.3","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"29.8","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"2.4","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"24.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"5.1","Cell RNA - GAMG [nTPM]":"3.2","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"10.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"5.0","Cell RNA - HSkMC [nTPM]":"2.5","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.7","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"25.1","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"2.7","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"20.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"3.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.0","Cell RNA - SK-BR-3 [nTPM]":"3.3","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"3.1","Cell RNA - U-2 OS [nTPM]":"7.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"4.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"1.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"69.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"20.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"39.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"49.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.5","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PITX3","Gene synonym":["ASMD"],"Ensembl":"ENSG00000107859","Gene description":"Paired like homeodomain 3","Uniprot":["O75364"],"Chromosome":"10","Position":"102230186-102241512","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"5.5","skeletal muscle":"16.5","tongue":"6.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Skeletal myocytes":"22.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"14","RNA brain regional specific nTPM":{"midbrain":"5.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"RH-30":"30.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"9.1"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"5.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"16.5","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"30.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"5.5","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PJVK","Gene synonym":["DFNB59"],"Ensembl":"ENSG00000204311","Gene description":"Pejvakin","Uniprot":["Q0ZLH3"],"Chromosome":"2","Position":"178451346-178462102","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"20.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"6.4","Alveolar cells type 2":"9.1","Distal tubular cells":"3.9","Granulosa cells":"6.1","Theca cells":"4.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"2.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"2.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SuSa":"6.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042621"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA042621":"AB_10797503"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"6.9","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"1.4","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"3.2","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"20.7","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"1.9","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"7.7","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"2.3","Cell RNA - AN3-CA [nTPM]":"1.9","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"3.1","Cell RNA - Daudi [nTPM]":"2.1","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"0.9","Cell RNA - HAP1 [nTPM]":"1.7","Cell RNA - HBEC3-KT [nTPM]":"1.0","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"2.9","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"3.2","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.4","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"3.8","Cell RNA - HUVEC TERT2 [nTPM]":"1.5","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"2.1","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"2.8","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"2.7","Cell RNA - RH-30 [nTPM]":"1.7","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"2.0","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"6.8","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"4.3","Cell RNA - U-266\/84 [nTPM]":"2.8","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"6.9","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"7.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PLA2G5","Gene synonym":[],"Ensembl":"ENSG00000127472","Gene description":"Phospholipase A2 group V","Uniprot":["P39877"],"Chromosome":"1","Position":"20028179-20091911","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Fatty acid metabolism","Lipid degradation","Lipid metabolism","Phagocytosis","Phospholipid degradation","Phospholipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"132.7","ovary":"47.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"75.3","Cone photoreceptor cells":"70.9","Leydig cells":"81.4","Peritubular cells":"73.4","Sertoli cells":"263.0","Smooth muscle cells":"63.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"13.0","prostate cancer":"3.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"1.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053361"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053361":"AB_2682127"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.9","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"22.1","Tissue RNA - colon [nTPM]":"33.7","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"132.7","Tissue RNA - hippocampal formation [nTPM]":"9.1","Tissue RNA - hypothalamus [nTPM]":"9.7","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"6.1","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"10.9","Tissue RNA - ovary [nTPM]":"47.6","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"9.2","Tissue RNA - prostate [nTPM]":"14.9","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"18.9","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"3.0","Tissue RNA - smooth muscle [nTPM]":"3.3","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"17.6","Tissue RNA - vagina [nTPM]":"1.7","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"9.1","Brain RNA - hypothalamus [nTPM]":"9.7","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"10.9","Brain RNA - pons [nTPM]":"9.2","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"25.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"75.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"30.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"81.4","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"30.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"73.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.1","Single Cell Type RNA - Sertoli cells [nTPM]":"263.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"63.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PLA2G6","Gene synonym":["iPLA2","iPLA2beta","NBIA2","PARK14","PNPLA9"],"Ensembl":"ENSG00000184381","Gene description":"Phospholipase A2 group VI","Uniprot":["O60733"],"Chromosome":"22","Position":"38111495-38214778","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Chemotaxis","Lipid metabolism","Phospholipid metabolism"],"Molecular function":["Calmodulin-binding","Hydrolase"],"Disease involvement":["Disease variant","Dystonia","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"28.5","Spermatocytes":"44.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"3.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"39.1","HMC-1":"25.6","U-266\/70":"20.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001171"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001171":"AB_1079145"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.29e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-4"},"Tissue RNA - adipose tissue [nTPM]":"20.0","Tissue RNA - adrenal gland [nTPM]":"22.2","Tissue RNA - amygdala [nTPM]":"14.1","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"16.6","Tissue RNA - bone marrow [nTPM]":"12.2","Tissue RNA - breast [nTPM]":"19.5","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"20.3","Tissue RNA - cervix [nTPM]":"24.9","Tissue RNA - choroid plexus [nTPM]":"12.3","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"17.8","Tissue RNA - epididymis [nTPM]":"10.6","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"26.2","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"9.5","Tissue RNA - hippocampal formation [nTPM]":"14.3","Tissue RNA - hypothalamus [nTPM]":"13.7","Tissue RNA - kidney [nTPM]":"24.0","Tissue RNA - liver [nTPM]":"13.3","Tissue RNA - lung [nTPM]":"10.4","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"17.2","Tissue RNA - midbrain [nTPM]":"15.0","Tissue RNA - ovary [nTPM]":"24.3","Tissue RNA - pancreas [nTPM]":"16.1","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"17.7","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"19.5","Tissue RNA - prostate [nTPM]":"24.9","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"15.9","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"10.7","Tissue RNA - skin 1 [nTPM]":"17.2","Tissue RNA - small intestine [nTPM]":"12.5","Tissue RNA - smooth muscle [nTPM]":"3.4","Tissue RNA - spinal cord [nTPM]":"15.3","Tissue RNA - spleen [nTPM]":"17.1","Tissue RNA - stomach 1 [nTPM]":"13.2","Tissue RNA - testis [nTPM]":"42.1","Tissue RNA - thalamus [nTPM]":"15.4","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"51.8","Tissue RNA - tongue [nTPM]":"4.4","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"13.2","Tissue RNA - vagina [nTPM]":"14.4","Tissue RNA - white matter [nTPM]":"25.5","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"6.3","Cell RNA - ASC diff [nTPM]":"8.0","Cell RNA - ASC TERT1 [nTPM]":"5.5","Cell RNA - BEWO [nTPM]":"9.8","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"3.2","Cell RNA - CAPAN-2 [nTPM]":"2.4","Cell RNA - Daudi [nTPM]":"5.9","Cell RNA - EFO-21 [nTPM]":"6.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"3.5","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"2.5","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"9.2","Cell RNA - HEK 293 [nTPM]":"11.1","Cell RNA - HEL [nTPM]":"39.1","Cell RNA - HeLa [nTPM]":"3.4","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"3.1","Cell RNA - HL-60 [nTPM]":"2.6","Cell RNA - HMC-1 [nTPM]":"25.6","Cell RNA - HSkMC [nTPM]":"13.3","Cell RNA - hTCEpi [nTPM]":"3.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.3","Cell RNA - hTERT-HME1 [nTPM]":"4.6","Cell RNA - hTERT-RPE1 [nTPM]":"6.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.8","Cell RNA - JURKAT [nTPM]":"11.7","Cell RNA - K-562 [nTPM]":"8.0","Cell RNA - Karpas-707 [nTPM]":"13.3","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"8.5","Cell RNA - NB-4 [nTPM]":"3.0","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"6.5","Cell RNA - RH-30 [nTPM]":"1.2","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"5.9","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"1.9","Cell RNA - SK-BR-3 [nTPM]":"3.1","Cell RNA - SK-MEL-30 [nTPM]":"6.7","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"4.1","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"2.1","Cell RNA - U-2 OS [nTPM]":"4.5","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"20.6","Cell RNA - U-266\/84 [nTPM]":"2.7","Cell RNA - U-698 [nTPM]":"4.0","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"3.2","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"3.7","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"14.1","Brain RNA - basal ganglia [nTPM]":"16.6","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"20.3","Brain RNA - hippocampal formation [nTPM]":"14.3","Brain RNA - hypothalamus [nTPM]":"13.7","Brain RNA - medulla oblongata [nTPM]":"17.2","Brain RNA - midbrain [nTPM]":"15.0","Brain RNA - pons [nTPM]":"19.5","Brain RNA - spinal cord [nTPM]":"15.3","Brain RNA - thalamus [nTPM]":"15.4","Brain RNA - white matter [nTPM]":"25.5","Single Cell Type RNA - Adipocytes [nTPM]":"5.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"4.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"9.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - dendritic cells [nTPM]":"11.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"28.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"3.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"18.3","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"12.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"4.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"44.5","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"6.6","Single Cell Type RNA - Theca cells [nTPM]":"6.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"PLCB1","Gene synonym":["KIAA0581","PLC-I","PLC154"],"Ensembl":"ENSG00000182621","Gene description":"Phospholipase C beta 1","Uniprot":["Q9NQ66"],"Chromosome":"20","Position":"8077251-8968360","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Transducer"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"74.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"563.5","Excitatory neurons":"2569.1","Inhibitory neurons":"1774.0","Oligodendrocyte precursor cells":"783.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"74.3"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"45.5","Hep G2":"68.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004275","CAB005334","HPA034743","HPA057910"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6600","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB004275":"AB_628118","CAB005334":"AB_632196","HPA034743":"AB_2674311","HPA057910":"AB_2683552"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"8.9","Tissue RNA - amygdala [nTPM]":"11.7","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"52.3","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"74.3","Tissue RNA - cervix [nTPM]":"8.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"18.1","Tissue RNA - duodenum [nTPM]":"7.2","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"17.4","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"13.2","Tissue RNA - liver [nTPM]":"4.3","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"3.7","Tissue RNA - pancreas [nTPM]":"14.7","Tissue RNA - parathyroid gland [nTPM]":"44.3","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"19.6","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"13.4","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"7.1","Tissue RNA - salivary gland [nTPM]":"29.0","Tissue RNA - seminal vesicle [nTPM]":"18.8","Tissue RNA - skeletal muscle [nTPM]":"14.4","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"3.6","Tissue RNA - stomach 1 [nTPM]":"8.0","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"9.8","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"15.9","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"23.8","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"8.7","Cell RNA - ASC TERT1 [nTPM]":"16.1","Cell RNA - BEWO [nTPM]":"6.3","Cell RNA - BJ [nTPM]":"20.2","Cell RNA - BJ hTERT+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"45.5","Cell RNA - CAPAN-2 [nTPM]":"5.0","Cell RNA - Daudi [nTPM]":"2.2","Cell RNA - EFO-21 [nTPM]":"8.2","Cell RNA - fHDF\/TERT166 [nTPM]":"3.9","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"3.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"3.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.4","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"3.5","Cell RNA - Hep G2 [nTPM]":"68.7","Cell RNA - HHSteC [nTPM]":"2.2","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.5","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"13.0","Cell RNA - K-562 [nTPM]":"7.1","Cell RNA - Karpas-707 [nTPM]":"26.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"6.2","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"3.3","Cell RNA - NTERA-2 [nTPM]":"15.0","Cell RNA - OE19 [nTPM]":"10.6","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"14.7","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"4.0","Cell RNA - RT4 [nTPM]":"16.8","Cell RNA - SCLC-21H [nTPM]":"16.9","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"4.1","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"17.1","Cell RNA - T-47d [nTPM]":"19.9","Cell RNA - THP-1 [nTPM]":"6.6","Cell RNA - TIME [nTPM]":"1.9","Cell RNA - U-138 MG [nTPM]":"16.8","Cell RNA - U-2 OS [nTPM]":"7.5","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"12.7","Cell RNA - U-266\/70 [nTPM]":"19.4","Cell RNA - U-266\/84 [nTPM]":"24.5","Cell RNA - U-698 [nTPM]":"33.9","Cell RNA - U-87 MG [nTPM]":"8.6","Cell RNA - U-937 [nTPM]":"12.6","Cell RNA - WM-115 [nTPM]":"29.5","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"11.7","Brain RNA - basal ganglia [nTPM]":"52.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"74.3","Brain RNA - hippocampal formation [nTPM]":"17.4","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"9.8","Brain RNA - white matter [nTPM]":"23.8","Single Cell Type RNA - Adipocytes [nTPM]":"74.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"563.5","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"7.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"2.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"16.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.1","Single Cell Type RNA - Endothelial cells [nTPM]":"54.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2569.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"25.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"83.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1774.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"211.7","Single Cell Type RNA - monocytes [nTPM]":"12.2","Single Cell Type RNA - Muller glia cells [nTPM]":"18.2","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"783.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"6.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.3","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"15.4","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"18.9"},{"Gene":"PLD3","Gene synonym":["HU-K4"],"Ensembl":"ENSG00000105223","Gene description":"Phospholipase D family member 3","Uniprot":["Q8IV08"],"Chromosome":"19","Position":"40348456-40380439","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response"],"Molecular function":["Exonuclease","Hydrolase","Nuclease"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"711.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"688.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1727.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"1727.4"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012800","CAB020812"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB020812":null,"HPA012800":"AB_1855330"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.44e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"169.3","Tissue RNA - adrenal gland [nTPM]":"200.0","Tissue RNA - amygdala [nTPM]":"143.3","Tissue RNA - appendix [nTPM]":"78.4","Tissue RNA - basal ganglia [nTPM]":"159.7","Tissue RNA - bone marrow [nTPM]":"48.3","Tissue RNA - breast [nTPM]":"138.4","Tissue RNA - cerebellum [nTPM]":"46.0","Tissue RNA - cerebral cortex [nTPM]":"229.7","Tissue RNA - cervix [nTPM]":"139.4","Tissue RNA - choroid plexus [nTPM]":"54.0","Tissue RNA - colon [nTPM]":"131.4","Tissue RNA - duodenum [nTPM]":"71.7","Tissue RNA - endometrium 1 [nTPM]":"155.7","Tissue RNA - epididymis [nTPM]":"84.7","Tissue RNA - esophagus [nTPM]":"84.9","Tissue RNA - fallopian tube [nTPM]":"133.5","Tissue RNA - gallbladder [nTPM]":"96.7","Tissue RNA - heart muscle [nTPM]":"206.1","Tissue RNA - hippocampal formation [nTPM]":"202.5","Tissue RNA - hypothalamus [nTPM]":"294.4","Tissue RNA - kidney [nTPM]":"130.2","Tissue RNA - liver [nTPM]":"121.3","Tissue RNA - lung [nTPM]":"181.5","Tissue RNA - lymph node [nTPM]":"98.1","Tissue RNA - medulla oblongata [nTPM]":"132.4","Tissue RNA - midbrain [nTPM]":"128.5","Tissue RNA - ovary [nTPM]":"199.0","Tissue RNA - pancreas [nTPM]":"151.0","Tissue RNA - parathyroid gland [nTPM]":"105.9","Tissue RNA - pituitary gland [nTPM]":"711.9","Tissue RNA - placenta [nTPM]":"123.4","Tissue RNA - pons [nTPM]":"137.9","Tissue RNA - prostate [nTPM]":"133.4","Tissue RNA - rectum [nTPM]":"49.2","Tissue RNA - retina [nTPM]":"51.4","Tissue RNA - salivary gland [nTPM]":"138.7","Tissue RNA - seminal vesicle [nTPM]":"106.2","Tissue RNA - skeletal muscle [nTPM]":"105.1","Tissue RNA - skin 1 [nTPM]":"120.5","Tissue RNA - small intestine [nTPM]":"105.3","Tissue RNA - smooth muscle [nTPM]":"79.1","Tissue RNA - spinal cord [nTPM]":"63.8","Tissue RNA - spleen [nTPM]":"197.0","Tissue RNA - stomach 1 [nTPM]":"126.5","Tissue RNA - testis [nTPM]":"77.7","Tissue RNA - thalamus [nTPM]":"197.7","Tissue RNA - thymus [nTPM]":"44.3","Tissue RNA - thyroid gland [nTPM]":"120.8","Tissue RNA - tongue [nTPM]":"82.3","Tissue RNA - tonsil [nTPM]":"41.4","Tissue RNA - urinary bladder [nTPM]":"126.2","Tissue RNA - vagina [nTPM]":"126.0","Tissue RNA - white matter [nTPM]":"129.6","Cell RNA - A-431 [nTPM]":"85.6","Cell RNA - A549 [nTPM]":"257.8","Cell RNA - AF22 [nTPM]":"163.7","Cell RNA - AN3-CA [nTPM]":"259.1","Cell RNA - ASC diff [nTPM]":"444.2","Cell RNA - ASC TERT1 [nTPM]":"210.2","Cell RNA - BEWO [nTPM]":"124.5","Cell RNA - BJ [nTPM]":"206.5","Cell RNA - BJ hTERT+ [nTPM]":"208.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"146.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"166.6","Cell RNA - CACO-2 [nTPM]":"49.4","Cell RNA - CAPAN-2 [nTPM]":"93.8","Cell RNA - Daudi [nTPM]":"36.9","Cell RNA - EFO-21 [nTPM]":"211.0","Cell RNA - fHDF\/TERT166 [nTPM]":"180.9","Cell RNA - GAMG [nTPM]":"47.8","Cell RNA - HaCaT [nTPM]":"39.3","Cell RNA - HAP1 [nTPM]":"39.9","Cell RNA - HBEC3-KT [nTPM]":"81.2","Cell RNA - HBF TERT88 [nTPM]":"63.5","Cell RNA - HDLM-2 [nTPM]":"138.4","Cell RNA - HEK 293 [nTPM]":"145.3","Cell RNA - HEL [nTPM]":"39.9","Cell RNA - HeLa [nTPM]":"82.1","Cell RNA - Hep G2 [nTPM]":"63.2","Cell RNA - HHSteC [nTPM]":"302.7","Cell RNA - HL-60 [nTPM]":"16.8","Cell RNA - HMC-1 [nTPM]":"435.1","Cell RNA - HSkMC [nTPM]":"402.5","Cell RNA - hTCEpi [nTPM]":"167.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.1","Cell RNA - hTERT-HME1 [nTPM]":"76.6","Cell RNA - hTERT-RPE1 [nTPM]":"244.2","Cell RNA - HUVEC TERT2 [nTPM]":"125.0","Cell RNA - JURKAT [nTPM]":"59.3","Cell RNA - K-562 [nTPM]":"142.5","Cell RNA - Karpas-707 [nTPM]":"144.5","Cell RNA - LHCN-M2 [nTPM]":"106.7","Cell RNA - MCF7 [nTPM]":"111.5","Cell RNA - MOLT-4 [nTPM]":"29.5","Cell RNA - NB-4 [nTPM]":"79.6","Cell RNA - NTERA-2 [nTPM]":"107.4","Cell RNA - OE19 [nTPM]":"138.7","Cell RNA - PC-3 [nTPM]":"52.8","Cell RNA - REH [nTPM]":"37.0","Cell RNA - RH-30 [nTPM]":"124.5","Cell RNA - RPMI-8226 [nTPM]":"154.2","Cell RNA - RPTEC TERT1 [nTPM]":"75.2","Cell RNA - RT4 [nTPM]":"63.2","Cell RNA - SCLC-21H [nTPM]":"116.7","Cell RNA - SH-SY5Y [nTPM]":"193.9","Cell RNA - SiHa [nTPM]":"99.0","Cell RNA - SK-BR-3 [nTPM]":"60.6","Cell RNA - SK-MEL-30 [nTPM]":"113.8","Cell RNA - SuSa [nTPM]":"169.5","Cell RNA - T-47d [nTPM]":"83.6","Cell RNA - THP-1 [nTPM]":"283.2","Cell RNA - TIME [nTPM]":"222.3","Cell RNA - U-138 MG [nTPM]":"122.8","Cell RNA - U-2 OS [nTPM]":"58.5","Cell RNA - U-2197 [nTPM]":"105.6","Cell RNA - U-251 MG [nTPM]":"47.0","Cell RNA - U-266\/70 [nTPM]":"148.9","Cell RNA - U-266\/84 [nTPM]":"173.3","Cell RNA - U-698 [nTPM]":"38.8","Cell RNA - U-87 MG [nTPM]":"197.7","Cell RNA - U-937 [nTPM]":"66.2","Cell RNA - WM-115 [nTPM]":"77.9","Blood RNA - basophil [nTPM]":"1727.4","Blood RNA - classical monocyte [nTPM]":"256.7","Blood RNA - eosinophil [nTPM]":"378.7","Blood RNA - gdT-cell [nTPM]":"75.0","Blood RNA - intermediate monocyte [nTPM]":"129.5","Blood RNA - MAIT T-cell [nTPM]":"62.0","Blood RNA - memory B-cell [nTPM]":"34.4","Blood RNA - memory CD4 T-cell [nTPM]":"59.5","Blood RNA - memory CD8 T-cell [nTPM]":"67.7","Blood RNA - myeloid DC [nTPM]":"235.0","Blood RNA - naive B-cell [nTPM]":"28.1","Blood RNA - naive CD4 T-cell [nTPM]":"60.8","Blood RNA - naive CD8 T-cell [nTPM]":"61.3","Blood RNA - neutrophil [nTPM]":"25.7","Blood RNA - NK-cell [nTPM]":"102.3","Blood RNA - non-classical monocyte [nTPM]":"64.2","Blood RNA - plasmacytoid DC [nTPM]":"34.7","Blood RNA - T-reg [nTPM]":"64.5","Blood RNA - total PBMC [nTPM]":"208.6","Brain RNA - amygdala [nTPM]":"143.3","Brain RNA - basal ganglia [nTPM]":"159.7","Brain RNA - cerebellum [nTPM]":"46.0","Brain RNA - cerebral cortex [nTPM]":"229.7","Brain RNA - hippocampal formation [nTPM]":"202.5","Brain RNA - hypothalamus [nTPM]":"294.4","Brain RNA - medulla oblongata [nTPM]":"132.4","Brain RNA - midbrain [nTPM]":"128.5","Brain RNA - pons [nTPM]":"137.9","Brain RNA - spinal cord [nTPM]":"63.8","Brain RNA - thalamus [nTPM]":"197.7","Brain RNA - white matter [nTPM]":"129.6","Single Cell Type RNA - Adipocytes [nTPM]":"66.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"69.6","Single Cell Type RNA - Astrocytes [nTPM]":"59.4","Single Cell Type RNA - B-cells [nTPM]":"27.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"93.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"263.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"101.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"61.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"90.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"57.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"158.2","Single Cell Type RNA - dendritic cells [nTPM]":"27.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"52.5","Single Cell Type RNA - Early spermatids [nTPM]":"8.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.8","Single Cell Type RNA - Endothelial cells [nTPM]":"53.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"72.8","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"99.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"58.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"107.2","Single Cell Type RNA - Fibroblasts [nTPM]":"158.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.5","Single Cell Type RNA - granulocytes [nTPM]":"60.3","Single Cell Type RNA - Granulosa cells [nTPM]":"134.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"88.2","Single Cell Type RNA - Hepatocytes [nTPM]":"43.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"688.4","Single Cell Type RNA - Horizontal cells [nTPM]":"121.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"113.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.3","Single Cell Type RNA - Ionocytes [nTPM]":"126.1","Single Cell Type RNA - Kupffer cells [nTPM]":"280.9","Single Cell Type RNA - Langerhans cells [nTPM]":"59.1","Single Cell Type RNA - Late spermatids [nTPM]":"15.7","Single Cell Type RNA - Leydig cells [nTPM]":"151.6","Single Cell Type RNA - Macrophages [nTPM]":"261.3","Single Cell Type RNA - Melanocytes [nTPM]":"92.5","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"54.2","Single Cell Type RNA - Muller glia cells [nTPM]":"94.1","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"53.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"70.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.3","Single Cell Type RNA - Paneth cells [nTPM]":"42.6","Single Cell Type RNA - Peritubular cells [nTPM]":"143.7","Single Cell Type RNA - Plasma cells [nTPM]":"85.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"57.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"78.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"47.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"73.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"59.7","Single Cell Type RNA - Spermatocytes [nTPM]":"24.2","Single Cell Type RNA - Spermatogonia [nTPM]":"67.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"195.9","Single Cell Type RNA - T-cells [nTPM]":"28.8","Single Cell Type RNA - Theca cells [nTPM]":"114.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.6","Single Cell Type RNA - Urothelial cells [nTPM]":"68.2"},{"Gene":"PLEKHG2","Gene synonym":["ARHGEF42","CLG","FLJ00018"],"Ensembl":"ENSG00000090924","Gene description":"Pleckstrin homology and RhoGEF domain containing G2","Uniprot":["Q9H7P9"],"Chromosome":"19","Position":"39412669-39428415","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Disease variant","Leukodystrophy","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"64.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"REH":"86.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017973","HPA048054"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA017973":"AB_2669719","HPA048054":"AB_2680241"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.53e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.79e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Tissue RNA - adipose tissue [nTPM]":"32.6","Tissue RNA - adrenal gland [nTPM]":"10.7","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"22.8","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"22.1","Tissue RNA - breast [nTPM]":"20.3","Tissue RNA - cerebellum [nTPM]":"4.6","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"28.2","Tissue RNA - choroid plexus [nTPM]":"11.3","Tissue RNA - colon [nTPM]":"24.5","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"31.2","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"24.9","Tissue RNA - gallbladder [nTPM]":"17.4","Tissue RNA - heart muscle [nTPM]":"25.6","Tissue RNA - hippocampal formation [nTPM]":"4.3","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"27.7","Tissue RNA - liver [nTPM]":"8.0","Tissue RNA - lung [nTPM]":"42.2","Tissue RNA - lymph node [nTPM]":"20.7","Tissue RNA - medulla oblongata [nTPM]":"7.1","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"20.1","Tissue RNA - pancreas [nTPM]":"7.1","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"12.2","Tissue RNA - placenta [nTPM]":"23.0","Tissue RNA - pons [nTPM]":"5.1","Tissue RNA - prostate [nTPM]":"21.0","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"15.1","Tissue RNA - skeletal muscle [nTPM]":"6.3","Tissue RNA - skin 1 [nTPM]":"9.0","Tissue RNA - small intestine [nTPM]":"18.9","Tissue RNA - smooth muscle [nTPM]":"18.5","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"33.4","Tissue RNA - stomach 1 [nTPM]":"15.6","Tissue RNA - testis [nTPM]":"15.7","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"21.1","Tissue RNA - thyroid gland [nTPM]":"19.1","Tissue RNA - tongue [nTPM]":"4.9","Tissue RNA - tonsil [nTPM]":"18.3","Tissue RNA - urinary bladder [nTPM]":"20.9","Tissue RNA - vagina [nTPM]":"17.4","Tissue RNA - white matter [nTPM]":"5.2","Cell RNA - A-431 [nTPM]":"8.5","Cell RNA - A549 [nTPM]":"40.8","Cell RNA - AF22 [nTPM]":"73.0","Cell RNA - AN3-CA [nTPM]":"39.9","Cell RNA - ASC diff [nTPM]":"6.9","Cell RNA - ASC TERT1 [nTPM]":"9.0","Cell RNA - BEWO [nTPM]":"10.6","Cell RNA - BJ [nTPM]":"21.9","Cell RNA - BJ hTERT+ [nTPM]":"17.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.8","Cell RNA - CACO-2 [nTPM]":"26.5","Cell RNA - CAPAN-2 [nTPM]":"14.9","Cell RNA - Daudi [nTPM]":"14.7","Cell RNA - EFO-21 [nTPM]":"15.8","Cell RNA - fHDF\/TERT166 [nTPM]":"28.8","Cell RNA - GAMG [nTPM]":"12.4","Cell RNA - HaCaT [nTPM]":"2.8","Cell RNA - HAP1 [nTPM]":"11.1","Cell RNA - HBEC3-KT [nTPM]":"19.4","Cell RNA - HBF TERT88 [nTPM]":"7.9","Cell RNA - HDLM-2 [nTPM]":"49.3","Cell RNA - HEK 293 [nTPM]":"10.2","Cell RNA - HEL [nTPM]":"19.3","Cell RNA - HeLa [nTPM]":"23.5","Cell RNA - Hep G2 [nTPM]":"12.4","Cell RNA - HHSteC [nTPM]":"11.9","Cell RNA - HL-60 [nTPM]":"2.2","Cell RNA - HMC-1 [nTPM]":"23.1","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"3.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.9","Cell RNA - hTERT-HME1 [nTPM]":"8.7","Cell RNA - hTERT-RPE1 [nTPM]":"25.8","Cell RNA - HUVEC TERT2 [nTPM]":"19.3","Cell RNA - JURKAT [nTPM]":"41.7","Cell RNA - K-562 [nTPM]":"13.2","Cell RNA - Karpas-707 [nTPM]":"16.9","Cell RNA - LHCN-M2 [nTPM]":"24.1","Cell RNA - MCF7 [nTPM]":"17.0","Cell RNA - MOLT-4 [nTPM]":"24.2","Cell RNA - NB-4 [nTPM]":"7.5","Cell RNA - NTERA-2 [nTPM]":"17.3","Cell RNA - OE19 [nTPM]":"7.8","Cell RNA - PC-3 [nTPM]":"3.9","Cell RNA - REH [nTPM]":"86.1","Cell RNA - RH-30 [nTPM]":"8.9","Cell RNA - RPMI-8226 [nTPM]":"4.6","Cell RNA - RPTEC TERT1 [nTPM]":"12.7","Cell RNA - RT4 [nTPM]":"15.4","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"23.6","Cell RNA - SiHa [nTPM]":"4.9","Cell RNA - SK-BR-3 [nTPM]":"1.8","Cell RNA - SK-MEL-30 [nTPM]":"7.0","Cell RNA - SuSa [nTPM]":"25.2","Cell RNA - T-47d [nTPM]":"21.9","Cell RNA - THP-1 [nTPM]":"21.8","Cell RNA - TIME [nTPM]":"24.8","Cell RNA - U-138 MG [nTPM]":"38.8","Cell RNA - U-2 OS [nTPM]":"30.0","Cell RNA - U-2197 [nTPM]":"14.5","Cell RNA - U-251 MG [nTPM]":"14.4","Cell RNA - U-266\/70 [nTPM]":"12.6","Cell RNA - U-266\/84 [nTPM]":"4.1","Cell RNA - U-698 [nTPM]":"21.4","Cell RNA - U-87 MG [nTPM]":"21.6","Cell RNA - U-937 [nTPM]":"8.7","Cell RNA - WM-115 [nTPM]":"22.0","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"4.6","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"4.3","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"7.1","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"5.1","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"5.2","Single Cell Type RNA - Adipocytes [nTPM]":"30.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"9.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"6.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"8.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.6","Single Cell Type RNA - Early spermatids [nTPM]":"14.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.1","Single Cell Type RNA - Endothelial cells [nTPM]":"17.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.9","Single Cell Type RNA - Fibroblasts [nTPM]":"16.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.8","Single Cell Type RNA - Langerhans cells [nTPM]":"21.1","Single Cell Type RNA - Late spermatids [nTPM]":"19.8","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"25.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"5.4","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.1","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"64.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"12.2","Single Cell Type RNA - Theca cells [nTPM]":"2.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"PLEKHG5","Gene synonym":["GEF720","KIAA0720","Syx","Tech"],"Ensembl":"ENSG00000171680","Gene description":"Pleckstrin homology and RhoGEF domain containing G5","Uniprot":["O94827"],"Chromosome":"1","Position":"6467122-6520074","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"57.4","skin 1":"102.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"17.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"57.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NB-4":"32.1","TIME":"30.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049570"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA049570":"AB_2680818"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.7","Tissue RNA - adrenal gland [nTPM]":"15.0","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"2.6","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"12.0","Tissue RNA - cerebellum [nTPM]":"57.4","Tissue RNA - cerebral cortex [nTPM]":"16.6","Tissue RNA - cervix [nTPM]":"14.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"7.3","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"7.5","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"21.6","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"16.4","Tissue RNA - hippocampal formation [nTPM]":"13.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"6.5","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"6.0","Tissue RNA - lymph node [nTPM]":"5.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"7.5","Tissue RNA - pancreas [nTPM]":"5.1","Tissue RNA - parathyroid gland [nTPM]":"4.4","Tissue RNA - pituitary gland [nTPM]":"43.3","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"7.2","Tissue RNA - skeletal muscle [nTPM]":"6.8","Tissue RNA - skin 1 [nTPM]":"102.5","Tissue RNA - small intestine [nTPM]":"8.4","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"50.9","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"5.4","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"7.2","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"5.9","Tissue RNA - vagina [nTPM]":"14.3","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"7.1","Cell RNA - A549 [nTPM]":"2.7","Cell RNA - AF22 [nTPM]":"11.9","Cell RNA - AN3-CA [nTPM]":"9.4","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"4.2","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"8.4","Cell RNA - BJ hTERT+ [nTPM]":"7.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.1","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"18.8","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"22.6","Cell RNA - fHDF\/TERT166 [nTPM]":"2.8","Cell RNA - GAMG [nTPM]":"4.9","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"23.7","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"16.5","Cell RNA - HEK 293 [nTPM]":"3.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"15.1","Cell RNA - Hep G2 [nTPM]":"2.9","Cell RNA - HHSteC [nTPM]":"1.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"5.5","Cell RNA - hTCEpi [nTPM]":"10.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.1","Cell RNA - hTERT-HME1 [nTPM]":"12.5","Cell RNA - hTERT-RPE1 [nTPM]":"17.4","Cell RNA - HUVEC TERT2 [nTPM]":"24.9","Cell RNA - JURKAT [nTPM]":"1.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"32.1","Cell RNA - NTERA-2 [nTPM]":"4.9","Cell RNA - OE19 [nTPM]":"2.3","Cell RNA - PC-3 [nTPM]":"23.8","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"2.7","Cell RNA - RPMI-8226 [nTPM]":"2.3","Cell RNA - RPTEC TERT1 [nTPM]":"6.3","Cell RNA - RT4 [nTPM]":"3.1","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"25.2","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"8.2","Cell RNA - SK-MEL-30 [nTPM]":"1.5","Cell RNA - SuSa [nTPM]":"5.3","Cell RNA - T-47d [nTPM]":"8.2","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"30.3","Cell RNA - U-138 MG [nTPM]":"8.1","Cell RNA - U-2 OS [nTPM]":"5.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"6.6","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"9.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"2.6","Brain RNA - cerebellum [nTPM]":"57.4","Brain RNA - cerebral cortex [nTPM]":"16.6","Brain RNA - hippocampal formation [nTPM]":"13.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"10.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.9","Single Cell Type RNA - Endothelial cells [nTPM]":"9.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"5.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.1","Single Cell Type RNA - Paneth cells [nTPM]":"5.6","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"2.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.8","Single Cell Type RNA - Urothelial cells [nTPM]":"5.8"},{"Gene":"PLP1","Gene synonym":["GPM6C","PLP","SPG2"],"Ensembl":"ENSG00000123560","Gene description":"Proteolipid protein 1","Uniprot":["P60201"],"Chromosome":"X","Position":"103773718-103792619","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary spastic paraplegia","Leukodystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"7004.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Oligodendrocytes":"4822.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"22","RNA cancer specific FPKM":{"glioma":"160.5","melanoma":"75.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SK-MEL-30":"241.0","WM-115":"139.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004128"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004128":"AB_1079635"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"15.7","Tissue RNA - amygdala [nTPM]":"2252.5","Tissue RNA - appendix [nTPM]":"4.2","Tissue RNA - basal ganglia [nTPM]":"4296.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"4251.8","Tissue RNA - cerebral cortex [nTPM]":"3472.7","Tissue RNA - cervix [nTPM]":"17.8","Tissue RNA - choroid plexus [nTPM]":"1056.0","Tissue RNA - colon [nTPM]":"73.9","Tissue RNA - duodenum [nTPM]":"6.3","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"6.7","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"30.1","Tissue RNA - hippocampal formation [nTPM]":"2314.1","Tissue RNA - hypothalamus [nTPM]":"2859.4","Tissue RNA - kidney [nTPM]":"2.9","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"5976.3","Tissue RNA - midbrain [nTPM]":"3571.3","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"83.1","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"5342.5","Tissue RNA - prostate [nTPM]":"21.1","Tissue RNA - rectum [nTPM]":"14.9","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"30.0","Tissue RNA - skeletal muscle [nTPM]":"2.4","Tissue RNA - skin 1 [nTPM]":"24.4","Tissue RNA - small intestine [nTPM]":"22.4","Tissue RNA - smooth muscle [nTPM]":"22.7","Tissue RNA - spinal cord [nTPM]":"3919.9","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"15.4","Tissue RNA - testis [nTPM]":"33.5","Tissue RNA - thalamus [nTPM]":"3592.5","Tissue RNA - thymus [nTPM]":"3.8","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"12.9","Tissue RNA - vagina [nTPM]":"21.8","Tissue RNA - white matter [nTPM]":"7004.9","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"20.7","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"1.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.4","Cell RNA - HSkMC [nTPM]":"4.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"2.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"37.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"241.0","Cell RNA - SuSa [nTPM]":"6.3","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"139.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2252.5","Brain RNA - basal ganglia [nTPM]":"4296.1","Brain RNA - cerebellum [nTPM]":"4251.8","Brain RNA - cerebral cortex [nTPM]":"3472.7","Brain RNA - hippocampal formation [nTPM]":"2314.1","Brain RNA - hypothalamus [nTPM]":"2859.4","Brain RNA - medulla oblongata [nTPM]":"5976.3","Brain RNA - midbrain [nTPM]":"3571.3","Brain RNA - pons [nTPM]":"5342.5","Brain RNA - spinal cord [nTPM]":"3919.9","Brain RNA - thalamus [nTPM]":"3592.5","Brain RNA - white matter [nTPM]":"7004.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"23.8","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"13.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"188.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"396.6","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"30.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4822.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"5.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PLPBP","Gene synonym":["PROSC"],"Ensembl":"ENSG00000147471","Gene description":"Pyridoxal phosphate binding protein","Uniprot":["O94903"],"Chromosome":"8","Position":"37762595-37779768","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"101.8","Exocrine glandular cells":"49.8","Hofbauer cells":"47.3","Proximal tubular cells":"82.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017033","HPA023646","HPA023733"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB017033":null,"HPA023646":"AB_1855741","HPA023733":"AB_1855742"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"34.2","Tissue RNA - adrenal gland [nTPM]":"23.1","Tissue RNA - amygdala [nTPM]":"22.2","Tissue RNA - appendix [nTPM]":"21.2","Tissue RNA - basal ganglia [nTPM]":"24.3","Tissue RNA - bone marrow [nTPM]":"14.6","Tissue RNA - breast [nTPM]":"23.3","Tissue RNA - cerebellum [nTPM]":"25.3","Tissue RNA - cerebral cortex [nTPM]":"27.1","Tissue RNA - cervix [nTPM]":"22.1","Tissue RNA - choroid plexus [nTPM]":"26.8","Tissue RNA - colon [nTPM]":"47.2","Tissue RNA - duodenum [nTPM]":"34.5","Tissue RNA - endometrium 1 [nTPM]":"19.2","Tissue RNA - epididymis [nTPM]":"23.3","Tissue RNA - esophagus [nTPM]":"20.2","Tissue RNA - fallopian tube [nTPM]":"27.5","Tissue RNA - gallbladder [nTPM]":"19.1","Tissue RNA - heart muscle [nTPM]":"39.2","Tissue RNA - hippocampal formation [nTPM]":"24.0","Tissue RNA - hypothalamus [nTPM]":"25.0","Tissue RNA - kidney [nTPM]":"58.5","Tissue RNA - liver [nTPM]":"78.2","Tissue RNA - lung [nTPM]":"25.7","Tissue RNA - lymph node [nTPM]":"25.0","Tissue RNA - medulla oblongata [nTPM]":"22.8","Tissue RNA - midbrain [nTPM]":"24.9","Tissue RNA - ovary [nTPM]":"24.7","Tissue RNA - pancreas [nTPM]":"40.3","Tissue RNA - parathyroid gland [nTPM]":"37.4","Tissue RNA - pituitary gland [nTPM]":"16.2","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"23.7","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"37.9","Tissue RNA - retina [nTPM]":"10.9","Tissue RNA - salivary gland [nTPM]":"28.3","Tissue RNA - seminal vesicle [nTPM]":"27.8","Tissue RNA - skeletal muscle [nTPM]":"46.4","Tissue RNA - skin 1 [nTPM]":"17.0","Tissue RNA - small intestine [nTPM]":"37.3","Tissue RNA - smooth muscle [nTPM]":"25.9","Tissue RNA - spinal cord [nTPM]":"23.7","Tissue RNA - spleen [nTPM]":"25.0","Tissue RNA - stomach 1 [nTPM]":"33.5","Tissue RNA - testis [nTPM]":"8.4","Tissue RNA - thalamus [nTPM]":"24.5","Tissue RNA - thymus [nTPM]":"27.4","Tissue RNA - thyroid gland [nTPM]":"31.8","Tissue RNA - tongue [nTPM]":"42.1","Tissue RNA - tonsil [nTPM]":"29.0","Tissue RNA - urinary bladder [nTPM]":"22.9","Tissue RNA - vagina [nTPM]":"16.1","Tissue RNA - white matter [nTPM]":"28.6","Cell RNA - A-431 [nTPM]":"50.3","Cell RNA - A549 [nTPM]":"45.4","Cell RNA - AF22 [nTPM]":"35.1","Cell RNA - AN3-CA [nTPM]":"32.0","Cell RNA - ASC diff [nTPM]":"25.9","Cell RNA - ASC TERT1 [nTPM]":"31.1","Cell RNA - BEWO [nTPM]":"31.6","Cell RNA - BJ [nTPM]":"55.2","Cell RNA - BJ hTERT+ [nTPM]":"45.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.9","Cell RNA - CACO-2 [nTPM]":"51.6","Cell RNA - CAPAN-2 [nTPM]":"24.3","Cell RNA - Daudi [nTPM]":"58.4","Cell RNA - EFO-21 [nTPM]":"61.9","Cell RNA - fHDF\/TERT166 [nTPM]":"39.9","Cell RNA - GAMG [nTPM]":"55.5","Cell RNA - HaCaT [nTPM]":"41.4","Cell RNA - HAP1 [nTPM]":"65.4","Cell RNA - HBEC3-KT [nTPM]":"52.5","Cell RNA - HBF TERT88 [nTPM]":"56.6","Cell RNA - HDLM-2 [nTPM]":"49.9","Cell RNA - HEK 293 [nTPM]":"34.3","Cell RNA - HEL [nTPM]":"79.4","Cell RNA - HeLa [nTPM]":"16.4","Cell RNA - Hep G2 [nTPM]":"51.7","Cell RNA - HHSteC [nTPM]":"51.6","Cell RNA - HL-60 [nTPM]":"36.8","Cell RNA - HMC-1 [nTPM]":"52.5","Cell RNA - HSkMC [nTPM]":"22.9","Cell RNA - hTCEpi [nTPM]":"49.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.0","Cell RNA - hTERT-HME1 [nTPM]":"52.0","Cell RNA - hTERT-RPE1 [nTPM]":"37.6","Cell RNA - HUVEC TERT2 [nTPM]":"52.3","Cell RNA - JURKAT [nTPM]":"78.3","Cell RNA - K-562 [nTPM]":"42.8","Cell RNA - Karpas-707 [nTPM]":"42.1","Cell RNA - LHCN-M2 [nTPM]":"28.7","Cell RNA - MCF7 [nTPM]":"34.8","Cell RNA - MOLT-4 [nTPM]":"116.4","Cell RNA - NB-4 [nTPM]":"32.4","Cell RNA - NTERA-2 [nTPM]":"43.0","Cell RNA - OE19 [nTPM]":"92.8","Cell RNA - PC-3 [nTPM]":"41.9","Cell RNA - REH [nTPM]":"73.6","Cell RNA - RH-30 [nTPM]":"46.6","Cell RNA - RPMI-8226 [nTPM]":"34.8","Cell RNA - RPTEC TERT1 [nTPM]":"56.5","Cell RNA - RT4 [nTPM]":"60.0","Cell RNA - SCLC-21H [nTPM]":"21.5","Cell RNA - SH-SY5Y [nTPM]":"25.1","Cell RNA - SiHa [nTPM]":"45.4","Cell RNA - SK-BR-3 [nTPM]":"20.0","Cell RNA - SK-MEL-30 [nTPM]":"56.8","Cell RNA - SuSa [nTPM]":"25.4","Cell RNA - T-47d [nTPM]":"44.2","Cell RNA - THP-1 [nTPM]":"48.6","Cell RNA - TIME [nTPM]":"52.1","Cell RNA - U-138 MG [nTPM]":"19.1","Cell RNA - U-2 OS [nTPM]":"60.7","Cell RNA - U-2197 [nTPM]":"69.8","Cell RNA - U-251 MG [nTPM]":"38.1","Cell RNA - U-266\/70 [nTPM]":"43.3","Cell RNA - U-266\/84 [nTPM]":"90.9","Cell RNA - U-698 [nTPM]":"43.0","Cell RNA - U-87 MG [nTPM]":"27.4","Cell RNA - U-937 [nTPM]":"51.8","Cell RNA - WM-115 [nTPM]":"35.0","Blood RNA - basophil [nTPM]":"164.3","Blood RNA - classical monocyte [nTPM]":"109.6","Blood RNA - eosinophil [nTPM]":"136.1","Blood RNA - gdT-cell [nTPM]":"85.6","Blood RNA - intermediate monocyte [nTPM]":"130.0","Blood RNA - MAIT T-cell [nTPM]":"90.0","Blood RNA - memory B-cell [nTPM]":"77.8","Blood RNA - memory CD4 T-cell [nTPM]":"87.8","Blood RNA - memory CD8 T-cell [nTPM]":"83.6","Blood RNA - myeloid DC [nTPM]":"115.2","Blood RNA - naive B-cell [nTPM]":"61.9","Blood RNA - naive CD4 T-cell [nTPM]":"77.0","Blood RNA - naive CD8 T-cell [nTPM]":"74.3","Blood RNA - neutrophil [nTPM]":"46.9","Blood RNA - NK-cell [nTPM]":"75.9","Blood RNA - non-classical monocyte [nTPM]":"147.4","Blood RNA - plasmacytoid DC [nTPM]":"66.5","Blood RNA - T-reg [nTPM]":"116.7","Blood RNA - total PBMC [nTPM]":"110.2","Brain RNA - amygdala [nTPM]":"22.2","Brain RNA - basal ganglia [nTPM]":"24.3","Brain RNA - cerebellum [nTPM]":"25.3","Brain RNA - cerebral cortex [nTPM]":"27.1","Brain RNA - hippocampal formation [nTPM]":"24.0","Brain RNA - hypothalamus [nTPM]":"25.0","Brain RNA - medulla oblongata [nTPM]":"22.8","Brain RNA - midbrain [nTPM]":"24.9","Brain RNA - pons [nTPM]":"23.7","Brain RNA - spinal cord [nTPM]":"23.7","Brain RNA - thalamus [nTPM]":"24.5","Brain RNA - white matter [nTPM]":"28.6","Single Cell Type RNA - Adipocytes [nTPM]":"35.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.2","Single Cell Type RNA - dendritic cells [nTPM]":"20.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"101.8","Single Cell Type RNA - Ductal cells [nTPM]":"38.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.6","Single Cell Type RNA - Fibroblasts [nTPM]":"13.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.6","Single Cell Type RNA - granulocytes [nTPM]":"12.6","Single Cell Type RNA - Granulosa cells [nTPM]":"14.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"47.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"18.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"11.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"82.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.9","Single Cell Type RNA - T-cells [nTPM]":"9.8","Single Cell Type RNA - Theca cells [nTPM]":"17.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PLS1","Gene synonym":["I-plastin","Plastin-1"],"Ensembl":"ENSG00000120756","Gene description":"Plastin 1","Uniprot":["Q14651"],"Chromosome":"3","Position":"142596393-142713664","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"315.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"471.4","Intestinal goblet cells":"147.9","Paneth cells":"200.5","Proximal enterocytes":"335.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"36.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"2.6","NK-cells":"3.2","T-cells":"2.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"90.0","BEWO":"112.3","OE19":"166.4","RPTEC TERT1":"143.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055744","HPA061936"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"56000000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055744":"AB_2682903","HPA061936":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.84e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.76e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"18.8","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"7.4","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"10.1","Tissue RNA - choroid plexus [nTPM]":"11.7","Tissue RNA - colon [nTPM]":"144.2","Tissue RNA - duodenum [nTPM]":"191.6","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"9.6","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"27.7","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"26.7","Tissue RNA - liver [nTPM]":"27.5","Tissue RNA - lung [nTPM]":"14.8","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"12.2","Tissue RNA - parathyroid gland [nTPM]":"15.7","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"3.1","Tissue RNA - rectum [nTPM]":"139.1","Tissue RNA - retina [nTPM]":"24.9","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"315.6","Tissue RNA - smooth muscle [nTPM]":"4.3","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"45.8","Tissue RNA - testis [nTPM]":"7.5","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"5.9","Tissue RNA - thyroid gland [nTPM]":"7.7","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"19.6","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"90.0","Cell RNA - A549 [nTPM]":"69.2","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"10.4","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"112.3","Cell RNA - BJ [nTPM]":"1.7","Cell RNA - BJ hTERT+ [nTPM]":"2.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.1","Cell RNA - CACO-2 [nTPM]":"31.7","Cell RNA - CAPAN-2 [nTPM]":"68.8","Cell RNA - Daudi [nTPM]":"15.2","Cell RNA - EFO-21 [nTPM]":"35.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"31.9","Cell RNA - HaCaT [nTPM]":"18.9","Cell RNA - HAP1 [nTPM]":"18.8","Cell RNA - HBEC3-KT [nTPM]":"28.7","Cell RNA - HBF TERT88 [nTPM]":"20.0","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"27.0","Cell RNA - HEL [nTPM]":"27.2","Cell RNA - HeLa [nTPM]":"10.2","Cell RNA - Hep G2 [nTPM]":"11.4","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"13.0","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"4.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.8","Cell RNA - hTERT-HME1 [nTPM]":"11.4","Cell RNA - hTERT-RPE1 [nTPM]":"14.8","Cell RNA - HUVEC TERT2 [nTPM]":"4.5","Cell RNA - JURKAT [nTPM]":"16.4","Cell RNA - K-562 [nTPM]":"11.8","Cell RNA - Karpas-707 [nTPM]":"1.7","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"21.0","Cell RNA - MOLT-4 [nTPM]":"21.4","Cell RNA - NB-4 [nTPM]":"7.0","Cell RNA - NTERA-2 [nTPM]":"18.9","Cell RNA - OE19 [nTPM]":"166.4","Cell RNA - PC-3 [nTPM]":"25.9","Cell RNA - REH [nTPM]":"8.7","Cell RNA - RH-30 [nTPM]":"20.3","Cell RNA - RPMI-8226 [nTPM]":"12.7","Cell RNA - RPTEC TERT1 [nTPM]":"143.6","Cell RNA - RT4 [nTPM]":"81.7","Cell RNA - SCLC-21H [nTPM]":"24.1","Cell RNA - SH-SY5Y [nTPM]":"9.7","Cell RNA - SiHa [nTPM]":"10.0","Cell RNA - SK-BR-3 [nTPM]":"7.0","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"13.3","Cell RNA - T-47d [nTPM]":"55.6","Cell RNA - THP-1 [nTPM]":"2.2","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"11.3","Cell RNA - U-2197 [nTPM]":"3.5","Cell RNA - U-251 MG [nTPM]":"21.3","Cell RNA - U-266\/70 [nTPM]":"12.7","Cell RNA - U-266\/84 [nTPM]":"12.6","Cell RNA - U-698 [nTPM]":"18.1","Cell RNA - U-87 MG [nTPM]":"3.2","Cell RNA - U-937 [nTPM]":"12.8","Cell RNA - WM-115 [nTPM]":"3.5","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"46.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"471.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"21.8","Single Cell Type RNA - Early spermatids [nTPM]":"64.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"53.9","Single Cell Type RNA - Erythroid cells [nTPM]":"5.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"50.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.8","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"32.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"31.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"147.9","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"20.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"70.2","Single Cell Type RNA - Paneth cells [nTPM]":"200.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"335.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.9","Single Cell Type RNA - Spermatocytes [nTPM]":"4.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"85.2","Single Cell Type RNA - Urothelial cells [nTPM]":"20.7"},{"Gene":"PMP2","Gene synonym":["FABP8","M-FABP","MP2"],"Ensembl":"ENSG00000147588","Gene description":"Peripheral myelin protein 2","Uniprot":["P02689"],"Chromosome":"8","Position":"81440326-81447439","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"50","RNA tissue specific nTPM":{"brain":"278.7","choroid plexus":"97.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Astrocytes":"84.9","Muller glia cells":"48.5","Oligodendrocyte precursor cells":"88.4","Oligodendrocytes":"90.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"59","RNA cancer specific FPKM":{"glioma":"239.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"WM-115":"1.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"9","RNA pig brain regional specific nTPM":{"spinal cord":"1313.6"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"155.1","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"168.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"231.4","Tissue RNA - cerebral cortex [nTPM]":"193.1","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"97.2","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"2.0","Tissue RNA - hippocampal formation [nTPM]":"146.1","Tissue RNA - hypothalamus [nTPM]":"206.4","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"278.7","Tissue RNA - midbrain [nTPM]":"243.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"257.4","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"3.7","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"247.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"214.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"275.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"155.1","Brain RNA - basal ganglia [nTPM]":"168.0","Brain RNA - cerebellum [nTPM]":"231.4","Brain RNA - cerebral cortex [nTPM]":"193.1","Brain RNA - hippocampal formation [nTPM]":"146.1","Brain RNA - hypothalamus [nTPM]":"206.4","Brain RNA - medulla oblongata [nTPM]":"278.7","Brain RNA - midbrain [nTPM]":"243.1","Brain RNA - pons [nTPM]":"257.4","Brain RNA - spinal cord [nTPM]":"247.1","Brain RNA - thalamus [nTPM]":"214.0","Brain RNA - white matter [nTPM]":"275.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"84.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"48.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"88.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"90.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PMP22","Gene synonym":["CMT1A","GAS3","HMSNIA","HNPP","Sp110"],"Ensembl":"ENSG00000109099","Gene description":"Peripheral myelin protein 22","Uniprot":["Q01453"],"Chromosome":"17","Position":"15229773-15272292","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Deafness","Dejerine-Sottas syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"404.1","Hofbauer cells":"558.3","Leydig cells":"324.3","Melanocytes":"343.3","Proximal enterocytes":"580.6","Skeletal myocytes":"288.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"32.2","eosinophil":"43.0","plasmacytoid DC":"23.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"dendritic cells":"23.8","granulocytes":"43.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"383.5","HMC-1":"263.7","SuSa":"333.9","WM-115":"448.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"275.6","Tissue RNA - adrenal gland [nTPM]":"45.4","Tissue RNA - amygdala [nTPM]":"113.6","Tissue RNA - appendix [nTPM]":"55.1","Tissue RNA - basal ganglia [nTPM]":"161.0","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"184.5","Tissue RNA - cerebellum [nTPM]":"153.2","Tissue RNA - cerebral cortex [nTPM]":"140.7","Tissue RNA - cervix [nTPM]":"192.2","Tissue RNA - choroid plexus [nTPM]":"77.9","Tissue RNA - colon [nTPM]":"212.2","Tissue RNA - duodenum [nTPM]":"41.7","Tissue RNA - endometrium 1 [nTPM]":"142.1","Tissue RNA - epididymis [nTPM]":"36.5","Tissue RNA - esophagus [nTPM]":"68.2","Tissue RNA - fallopian tube [nTPM]":"163.4","Tissue RNA - gallbladder [nTPM]":"106.5","Tissue RNA - heart muscle [nTPM]":"167.6","Tissue RNA - hippocampal formation [nTPM]":"113.5","Tissue RNA - hypothalamus [nTPM]":"129.0","Tissue RNA - kidney [nTPM]":"53.5","Tissue RNA - liver [nTPM]":"11.7","Tissue RNA - lung [nTPM]":"208.4","Tissue RNA - lymph node [nTPM]":"27.8","Tissue RNA - medulla oblongata [nTPM]":"163.3","Tissue RNA - midbrain [nTPM]":"144.2","Tissue RNA - ovary [nTPM]":"102.9","Tissue RNA - pancreas [nTPM]":"22.8","Tissue RNA - parathyroid gland [nTPM]":"10.8","Tissue RNA - pituitary gland [nTPM]":"26.3","Tissue RNA - placenta [nTPM]":"201.9","Tissue RNA - pons [nTPM]":"159.9","Tissue RNA - prostate [nTPM]":"81.2","Tissue RNA - rectum [nTPM]":"74.7","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"77.5","Tissue RNA - seminal vesicle [nTPM]":"80.6","Tissue RNA - skeletal muscle [nTPM]":"252.4","Tissue RNA - skin 1 [nTPM]":"112.7","Tissue RNA - small intestine [nTPM]":"239.1","Tissue RNA - smooth muscle [nTPM]":"122.0","Tissue RNA - spinal cord [nTPM]":"135.0","Tissue RNA - spleen [nTPM]":"27.9","Tissue RNA - stomach 1 [nTPM]":"96.2","Tissue RNA - testis [nTPM]":"20.7","Tissue RNA - thalamus [nTPM]":"141.1","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"95.3","Tissue RNA - tongue [nTPM]":"127.0","Tissue RNA - tonsil [nTPM]":"21.8","Tissue RNA - urinary bladder [nTPM]":"208.9","Tissue RNA - vagina [nTPM]":"157.4","Tissue RNA - white matter [nTPM]":"216.7","Cell RNA - A-431 [nTPM]":"7.0","Cell RNA - A549 [nTPM]":"44.1","Cell RNA - AF22 [nTPM]":"61.9","Cell RNA - AN3-CA [nTPM]":"62.2","Cell RNA - ASC diff [nTPM]":"383.5","Cell RNA - ASC TERT1 [nTPM]":"167.1","Cell RNA - BEWO [nTPM]":"12.6","Cell RNA - BJ [nTPM]":"60.5","Cell RNA - BJ hTERT+ [nTPM]":"68.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"58.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.0","Cell RNA - CACO-2 [nTPM]":"48.7","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"7.0","Cell RNA - fHDF\/TERT166 [nTPM]":"172.3","Cell RNA - GAMG [nTPM]":"22.7","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"74.0","Cell RNA - HBEC3-KT [nTPM]":"1.1","Cell RNA - HBF TERT88 [nTPM]":"15.4","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"13.9","Cell RNA - HEL [nTPM]":"4.3","Cell RNA - HeLa [nTPM]":"76.7","Cell RNA - Hep G2 [nTPM]":"17.2","Cell RNA - HHSteC [nTPM]":"201.8","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"263.7","Cell RNA - HSkMC [nTPM]":"126.9","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.6","Cell RNA - hTERT-HME1 [nTPM]":"1.8","Cell RNA - hTERT-RPE1 [nTPM]":"72.1","Cell RNA - HUVEC TERT2 [nTPM]":"66.1","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"24.5","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"33.2","Cell RNA - MCF7 [nTPM]":"6.1","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"2.0","Cell RNA - NTERA-2 [nTPM]":"3.5","Cell RNA - OE19 [nTPM]":"4.0","Cell RNA - PC-3 [nTPM]":"74.7","Cell RNA - REH [nTPM]":"22.0","Cell RNA - RH-30 [nTPM]":"39.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"44.6","Cell RNA - RT4 [nTPM]":"4.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"40.6","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"134.2","Cell RNA - SuSa [nTPM]":"333.9","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"81.4","Cell RNA - U-138 MG [nTPM]":"12.7","Cell RNA - U-2 OS [nTPM]":"45.7","Cell RNA - U-2197 [nTPM]":"216.9","Cell RNA - U-251 MG [nTPM]":"62.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"84.7","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"448.8","Blood RNA - basophil [nTPM]":"32.2","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"43.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"7.6","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"23.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"113.6","Brain RNA - basal ganglia [nTPM]":"161.0","Brain RNA - cerebellum [nTPM]":"153.2","Brain RNA - cerebral cortex [nTPM]":"140.7","Brain RNA - hippocampal formation [nTPM]":"113.5","Brain RNA - hypothalamus [nTPM]":"129.0","Brain RNA - medulla oblongata [nTPM]":"163.3","Brain RNA - midbrain [nTPM]":"144.2","Brain RNA - pons [nTPM]":"159.9","Brain RNA - spinal cord [nTPM]":"135.0","Brain RNA - thalamus [nTPM]":"141.1","Brain RNA - white matter [nTPM]":"216.7","Single Cell Type RNA - Adipocytes [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"50.9","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"90.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"82.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"68.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"7.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"2.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.5","Single Cell Type RNA - Early spermatids [nTPM]":"17.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"118.6","Single Cell Type RNA - Endothelial cells [nTPM]":"148.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"10.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.1","Single Cell Type RNA - Fibroblasts [nTPM]":"404.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"119.7","Single Cell Type RNA - Granulosa cells [nTPM]":"25.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"88.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"558.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"23.4","Single Cell Type RNA - Langerhans cells [nTPM]":"116.8","Single Cell Type RNA - Late spermatids [nTPM]":"11.0","Single Cell Type RNA - Leydig cells [nTPM]":"324.3","Single Cell Type RNA - Macrophages [nTPM]":"93.0","Single Cell Type RNA - Melanocytes [nTPM]":"343.3","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"11.8","Single Cell Type RNA - Muller glia cells [nTPM]":"61.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"46.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"25.2","Single Cell Type RNA - Peritubular cells [nTPM]":"246.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"580.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"230.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"288.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"141.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"103.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.0","Single Cell Type RNA - T-cells [nTPM]":"8.7","Single Cell Type RNA - Theca cells [nTPM]":"49.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.9","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"PMPCA","Gene synonym":["Alpha-MPP","CLA1","INPP5E","KIAA0123","SCAR2"],"Ensembl":"ENSG00000165688","Gene description":"Peptidase, mitochondrial processing subunit alpha","Uniprot":["Q10713"],"Chromosome":"9","Position":"136410641-136423761","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021648","HPA063735"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA021648":"AB_1855491","HPA063735":"AB_2685108"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.00e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.2","Tissue RNA - adrenal gland [nTPM]":"58.1","Tissue RNA - amygdala [nTPM]":"27.0","Tissue RNA - appendix [nTPM]":"20.6","Tissue RNA - basal ganglia [nTPM]":"27.6","Tissue RNA - bone marrow [nTPM]":"31.4","Tissue RNA - breast [nTPM]":"27.1","Tissue RNA - cerebellum [nTPM]":"27.0","Tissue RNA - cerebral cortex [nTPM]":"34.6","Tissue RNA - cervix [nTPM]":"29.2","Tissue RNA - choroid plexus [nTPM]":"36.8","Tissue RNA - colon [nTPM]":"32.2","Tissue RNA - duodenum [nTPM]":"24.8","Tissue RNA - endometrium 1 [nTPM]":"26.8","Tissue RNA - epididymis [nTPM]":"10.4","Tissue RNA - esophagus [nTPM]":"34.5","Tissue RNA - fallopian tube [nTPM]":"27.5","Tissue RNA - gallbladder [nTPM]":"17.9","Tissue RNA - heart muscle [nTPM]":"73.2","Tissue RNA - hippocampal formation [nTPM]":"28.0","Tissue RNA - hypothalamus [nTPM]":"27.3","Tissue RNA - kidney [nTPM]":"37.3","Tissue RNA - liver [nTPM]":"110.8","Tissue RNA - lung [nTPM]":"25.4","Tissue RNA - lymph node [nTPM]":"27.1","Tissue RNA - medulla oblongata [nTPM]":"27.1","Tissue RNA - midbrain [nTPM]":"27.6","Tissue RNA - ovary [nTPM]":"29.3","Tissue RNA - pancreas [nTPM]":"28.8","Tissue RNA - parathyroid gland [nTPM]":"26.9","Tissue RNA - pituitary gland [nTPM]":"38.8","Tissue RNA - placenta [nTPM]":"20.8","Tissue RNA - pons [nTPM]":"27.9","Tissue RNA - prostate [nTPM]":"31.8","Tissue RNA - rectum [nTPM]":"15.3","Tissue RNA - retina [nTPM]":"8.8","Tissue RNA - salivary gland [nTPM]":"28.4","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"69.2","Tissue RNA - skin 1 [nTPM]":"37.6","Tissue RNA - small intestine [nTPM]":"30.6","Tissue RNA - smooth muscle [nTPM]":"15.3","Tissue RNA - spinal cord [nTPM]":"25.6","Tissue RNA - spleen [nTPM]":"38.2","Tissue RNA - stomach 1 [nTPM]":"35.3","Tissue RNA - testis [nTPM]":"37.8","Tissue RNA - thalamus [nTPM]":"27.9","Tissue RNA - thymus [nTPM]":"21.4","Tissue RNA - thyroid gland [nTPM]":"29.4","Tissue RNA - tongue [nTPM]":"50.0","Tissue RNA - tonsil [nTPM]":"17.0","Tissue RNA - urinary bladder [nTPM]":"28.0","Tissue RNA - vagina [nTPM]":"27.8","Tissue RNA - white matter [nTPM]":"26.7","Cell RNA - A-431 [nTPM]":"48.7","Cell RNA - A549 [nTPM]":"87.7","Cell RNA - AF22 [nTPM]":"41.8","Cell RNA - AN3-CA [nTPM]":"84.5","Cell RNA - ASC diff [nTPM]":"30.8","Cell RNA - ASC TERT1 [nTPM]":"45.0","Cell RNA - BEWO [nTPM]":"63.2","Cell RNA - BJ [nTPM]":"49.3","Cell RNA - BJ hTERT+ [nTPM]":"39.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.9","Cell RNA - CACO-2 [nTPM]":"101.1","Cell RNA - CAPAN-2 [nTPM]":"56.5","Cell RNA - Daudi [nTPM]":"67.4","Cell RNA - EFO-21 [nTPM]":"50.5","Cell RNA - fHDF\/TERT166 [nTPM]":"50.3","Cell RNA - GAMG [nTPM]":"36.2","Cell RNA - HaCaT [nTPM]":"110.2","Cell RNA - HAP1 [nTPM]":"77.9","Cell RNA - HBEC3-KT [nTPM]":"72.0","Cell RNA - HBF TERT88 [nTPM]":"30.0","Cell RNA - HDLM-2 [nTPM]":"97.2","Cell RNA - HEK 293 [nTPM]":"92.8","Cell RNA - HEL [nTPM]":"54.6","Cell RNA - HeLa [nTPM]":"113.2","Cell RNA - Hep G2 [nTPM]":"123.6","Cell RNA - HHSteC [nTPM]":"53.9","Cell RNA - HL-60 [nTPM]":"71.7","Cell RNA - HMC-1 [nTPM]":"44.9","Cell RNA - HSkMC [nTPM]":"66.3","Cell RNA - hTCEpi [nTPM]":"48.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"52.6","Cell RNA - hTERT-HME1 [nTPM]":"27.0","Cell RNA - hTERT-RPE1 [nTPM]":"38.2","Cell RNA - HUVEC TERT2 [nTPM]":"58.0","Cell RNA - JURKAT [nTPM]":"61.2","Cell RNA - K-562 [nTPM]":"140.2","Cell RNA - Karpas-707 [nTPM]":"43.4","Cell RNA - LHCN-M2 [nTPM]":"42.6","Cell RNA - MCF7 [nTPM]":"132.1","Cell RNA - MOLT-4 [nTPM]":"68.1","Cell RNA - NB-4 [nTPM]":"90.1","Cell RNA - NTERA-2 [nTPM]":"85.4","Cell RNA - OE19 [nTPM]":"86.2","Cell RNA - PC-3 [nTPM]":"82.2","Cell RNA - REH [nTPM]":"83.0","Cell RNA - RH-30 [nTPM]":"59.1","Cell RNA - RPMI-8226 [nTPM]":"149.9","Cell RNA - RPTEC TERT1 [nTPM]":"46.3","Cell RNA - RT4 [nTPM]":"33.9","Cell RNA - SCLC-21H [nTPM]":"85.4","Cell RNA - SH-SY5Y [nTPM]":"56.1","Cell RNA - SiHa [nTPM]":"66.6","Cell RNA - SK-BR-3 [nTPM]":"92.9","Cell RNA - SK-MEL-30 [nTPM]":"58.6","Cell RNA - SuSa [nTPM]":"28.6","Cell RNA - T-47d [nTPM]":"127.6","Cell RNA - THP-1 [nTPM]":"95.5","Cell RNA - TIME [nTPM]":"48.2","Cell RNA - U-138 MG [nTPM]":"47.8","Cell RNA - U-2 OS [nTPM]":"50.7","Cell RNA - U-2197 [nTPM]":"39.8","Cell RNA - U-251 MG [nTPM]":"63.8","Cell RNA - U-266\/70 [nTPM]":"26.2","Cell RNA - U-266\/84 [nTPM]":"37.4","Cell RNA - U-698 [nTPM]":"73.5","Cell RNA - U-87 MG [nTPM]":"62.9","Cell RNA - U-937 [nTPM]":"61.3","Cell RNA - WM-115 [nTPM]":"43.9","Blood RNA - basophil [nTPM]":"37.4","Blood RNA - classical monocyte [nTPM]":"50.5","Blood RNA - eosinophil [nTPM]":"36.5","Blood RNA - gdT-cell [nTPM]":"53.2","Blood RNA - intermediate monocyte [nTPM]":"51.9","Blood RNA - MAIT T-cell [nTPM]":"51.4","Blood RNA - memory B-cell [nTPM]":"52.5","Blood RNA - memory CD4 T-cell [nTPM]":"49.0","Blood RNA - memory CD8 T-cell [nTPM]":"57.2","Blood RNA - myeloid DC [nTPM]":"61.7","Blood RNA - naive B-cell [nTPM]":"48.8","Blood RNA - naive CD4 T-cell [nTPM]":"57.9","Blood RNA - naive CD8 T-cell [nTPM]":"50.2","Blood RNA - neutrophil [nTPM]":"11.9","Blood RNA - NK-cell [nTPM]":"67.2","Blood RNA - non-classical monocyte [nTPM]":"51.5","Blood RNA - plasmacytoid DC [nTPM]":"31.4","Blood RNA - T-reg [nTPM]":"52.7","Blood RNA - total PBMC [nTPM]":"62.2","Brain RNA - amygdala [nTPM]":"27.0","Brain RNA - basal ganglia [nTPM]":"27.6","Brain RNA - cerebellum [nTPM]":"27.0","Brain RNA - cerebral cortex [nTPM]":"34.6","Brain RNA - hippocampal formation [nTPM]":"28.0","Brain RNA - hypothalamus [nTPM]":"27.3","Brain RNA - medulla oblongata [nTPM]":"27.1","Brain RNA - midbrain [nTPM]":"27.6","Brain RNA - pons [nTPM]":"27.9","Brain RNA - spinal cord [nTPM]":"25.6","Brain RNA - thalamus [nTPM]":"27.9","Brain RNA - white matter [nTPM]":"26.7","Single Cell Type RNA - Adipocytes [nTPM]":"17.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"24.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"65.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"24.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"32.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"103.1","Single Cell Type RNA - dendritic cells [nTPM]":"22.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"32.9","Single Cell Type RNA - Early spermatids [nTPM]":"24.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.5","Single Cell Type RNA - Endothelial cells [nTPM]":"21.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.8","Single Cell Type RNA - Erythroid cells [nTPM]":"23.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"50.4","Single Cell Type RNA - Fibroblasts [nTPM]":"23.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.2","Single Cell Type RNA - granulocytes [nTPM]":"24.7","Single Cell Type RNA - Granulosa cells [nTPM]":"44.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"57.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.8","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"19.2","Single Cell Type RNA - Langerhans cells [nTPM]":"14.6","Single Cell Type RNA - Late spermatids [nTPM]":"15.8","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"17.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"21.0","Single Cell Type RNA - Muller glia cells [nTPM]":"22.9","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.6","Single Cell Type RNA - Paneth cells [nTPM]":"20.9","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"26.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.9","Single Cell Type RNA - Spermatocytes [nTPM]":"37.7","Single Cell Type RNA - Spermatogonia [nTPM]":"42.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"103.8","Single Cell Type RNA - T-cells [nTPM]":"21.7","Single Cell Type RNA - Theca cells [nTPM]":"77.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"38.6","Single Cell Type RNA - Urothelial cells [nTPM]":"28.5"},{"Gene":"PNKD","Gene synonym":["BRP17","DKFZp564N1362","DYT8","FKSG19","FPD1","KIAA1184","KIPP1184","MGC31943","MR-1","MR-1S","PDC","PKND1","TAHCCP2"],"Ensembl":"ENSG00000127838","Gene description":"PNKD metallo-beta-lactamase domain containing","Uniprot":["Q8N490"],"Chromosome":"2","Position":"218270392-218346793","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"508.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010134","HPA017068"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA010134":"AB_1079645","HPA017068":"AB_1855495"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.13e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Tissue RNA - adipose tissue [nTPM]":"50.9","Tissue RNA - adrenal gland [nTPM]":"88.9","Tissue RNA - amygdala [nTPM]":"127.6","Tissue RNA - appendix [nTPM]":"33.3","Tissue RNA - basal ganglia [nTPM]":"134.7","Tissue RNA - bone marrow [nTPM]":"35.4","Tissue RNA - breast [nTPM]":"49.7","Tissue RNA - cerebellum [nTPM]":"131.2","Tissue RNA - cerebral cortex [nTPM]":"168.4","Tissue RNA - cervix [nTPM]":"62.8","Tissue RNA - choroid plexus [nTPM]":"129.3","Tissue RNA - colon [nTPM]":"74.7","Tissue RNA - duodenum [nTPM]":"40.6","Tissue RNA - endometrium 1 [nTPM]":"45.6","Tissue RNA - epididymis [nTPM]":"77.3","Tissue RNA - esophagus [nTPM]":"40.5","Tissue RNA - fallopian tube [nTPM]":"60.6","Tissue RNA - gallbladder [nTPM]":"41.6","Tissue RNA - heart muscle [nTPM]":"98.4","Tissue RNA - hippocampal formation [nTPM]":"127.8","Tissue RNA - hypothalamus [nTPM]":"137.5","Tissue RNA - kidney [nTPM]":"106.5","Tissue RNA - liver [nTPM]":"191.5","Tissue RNA - lung [nTPM]":"55.5","Tissue RNA - lymph node [nTPM]":"40.9","Tissue RNA - medulla oblongata [nTPM]":"133.9","Tissue RNA - midbrain [nTPM]":"130.9","Tissue RNA - ovary [nTPM]":"47.1","Tissue RNA - pancreas [nTPM]":"46.1","Tissue RNA - parathyroid gland [nTPM]":"93.4","Tissue RNA - pituitary gland [nTPM]":"49.5","Tissue RNA - placenta [nTPM]":"46.9","Tissue RNA - pons [nTPM]":"134.1","Tissue RNA - prostate [nTPM]":"87.4","Tissue RNA - rectum [nTPM]":"54.7","Tissue RNA - retina [nTPM]":"26.7","Tissue RNA - salivary gland [nTPM]":"60.6","Tissue RNA - seminal vesicle [nTPM]":"55.3","Tissue RNA - skeletal muscle [nTPM]":"85.1","Tissue RNA - skin 1 [nTPM]":"44.9","Tissue RNA - small intestine [nTPM]":"51.1","Tissue RNA - smooth muscle [nTPM]":"36.4","Tissue RNA - spinal cord [nTPM]":"128.7","Tissue RNA - spleen [nTPM]":"58.7","Tissue RNA - stomach 1 [nTPM]":"81.6","Tissue RNA - testis [nTPM]":"45.6","Tissue RNA - thalamus [nTPM]":"137.8","Tissue RNA - thymus [nTPM]":"45.8","Tissue RNA - thyroid gland [nTPM]":"90.0","Tissue RNA - tongue [nTPM]":"93.6","Tissue RNA - tonsil [nTPM]":"37.6","Tissue RNA - urinary bladder [nTPM]":"64.2","Tissue RNA - vagina [nTPM]":"45.4","Tissue RNA - white matter [nTPM]":"134.7","Cell RNA - A-431 [nTPM]":"53.2","Cell RNA - A549 [nTPM]":"68.3","Cell RNA - AF22 [nTPM]":"49.1","Cell RNA - AN3-CA [nTPM]":"77.0","Cell RNA - ASC diff [nTPM]":"72.2","Cell RNA - ASC TERT1 [nTPM]":"60.6","Cell RNA - BEWO [nTPM]":"90.0","Cell RNA - BJ [nTPM]":"32.7","Cell RNA - BJ hTERT+ [nTPM]":"70.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"76.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"85.0","Cell RNA - CACO-2 [nTPM]":"112.9","Cell RNA - CAPAN-2 [nTPM]":"51.2","Cell RNA - Daudi [nTPM]":"61.7","Cell RNA - EFO-21 [nTPM]":"63.7","Cell RNA - fHDF\/TERT166 [nTPM]":"55.0","Cell RNA - GAMG [nTPM]":"83.5","Cell RNA - HaCaT [nTPM]":"53.6","Cell RNA - HAP1 [nTPM]":"95.4","Cell RNA - HBEC3-KT [nTPM]":"61.4","Cell RNA - HBF TERT88 [nTPM]":"52.9","Cell RNA - HDLM-2 [nTPM]":"128.0","Cell RNA - HEK 293 [nTPM]":"119.4","Cell RNA - HEL [nTPM]":"90.0","Cell RNA - HeLa [nTPM]":"119.5","Cell RNA - Hep G2 [nTPM]":"169.4","Cell RNA - HHSteC [nTPM]":"78.7","Cell RNA - HL-60 [nTPM]":"58.9","Cell RNA - HMC-1 [nTPM]":"38.6","Cell RNA - HSkMC [nTPM]":"83.0","Cell RNA - hTCEpi [nTPM]":"59.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"51.9","Cell RNA - hTERT-HME1 [nTPM]":"15.0","Cell RNA - hTERT-RPE1 [nTPM]":"51.0","Cell RNA - HUVEC TERT2 [nTPM]":"83.2","Cell RNA - JURKAT [nTPM]":"48.0","Cell RNA - K-562 [nTPM]":"67.8","Cell RNA - Karpas-707 [nTPM]":"78.3","Cell RNA - LHCN-M2 [nTPM]":"68.4","Cell RNA - MCF7 [nTPM]":"152.2","Cell RNA - MOLT-4 [nTPM]":"77.6","Cell RNA - NB-4 [nTPM]":"139.5","Cell RNA - NTERA-2 [nTPM]":"49.0","Cell RNA - OE19 [nTPM]":"121.3","Cell RNA - PC-3 [nTPM]":"69.3","Cell RNA - REH [nTPM]":"75.1","Cell RNA - RH-30 [nTPM]":"49.5","Cell RNA - RPMI-8226 [nTPM]":"51.8","Cell RNA - RPTEC TERT1 [nTPM]":"88.3","Cell RNA - RT4 [nTPM]":"79.2","Cell RNA - SCLC-21H [nTPM]":"47.4","Cell RNA - SH-SY5Y [nTPM]":"39.9","Cell RNA - SiHa [nTPM]":"23.6","Cell RNA - SK-BR-3 [nTPM]":"156.9","Cell RNA - SK-MEL-30 [nTPM]":"94.6","Cell RNA - SuSa [nTPM]":"52.0","Cell RNA - T-47d [nTPM]":"52.4","Cell RNA - THP-1 [nTPM]":"56.4","Cell RNA - TIME [nTPM]":"51.5","Cell RNA - U-138 MG [nTPM]":"31.4","Cell RNA - U-2 OS [nTPM]":"53.7","Cell RNA - U-2197 [nTPM]":"37.5","Cell RNA - U-251 MG [nTPM]":"45.5","Cell RNA - U-266\/70 [nTPM]":"32.4","Cell RNA - U-266\/84 [nTPM]":"35.7","Cell RNA - U-698 [nTPM]":"69.0","Cell RNA - U-87 MG [nTPM]":"79.9","Cell RNA - U-937 [nTPM]":"95.8","Cell RNA - WM-115 [nTPM]":"38.8","Blood RNA - basophil [nTPM]":"142.4","Blood RNA - classical monocyte [nTPM]":"111.4","Blood RNA - eosinophil [nTPM]":"151.9","Blood RNA - gdT-cell [nTPM]":"97.7","Blood RNA - intermediate monocyte [nTPM]":"114.3","Blood RNA - MAIT T-cell [nTPM]":"94.2","Blood RNA - memory B-cell [nTPM]":"223.1","Blood RNA - memory CD4 T-cell [nTPM]":"105.7","Blood RNA - memory CD8 T-cell [nTPM]":"117.7","Blood RNA - myeloid DC [nTPM]":"106.4","Blood RNA - naive B-cell [nTPM]":"187.2","Blood RNA - naive CD4 T-cell [nTPM]":"116.4","Blood RNA - naive CD8 T-cell [nTPM]":"111.2","Blood RNA - neutrophil [nTPM]":"31.3","Blood RNA - NK-cell [nTPM]":"136.2","Blood RNA - non-classical monocyte [nTPM]":"109.4","Blood RNA - plasmacytoid DC [nTPM]":"99.0","Blood RNA - T-reg [nTPM]":"150.0","Blood RNA - total PBMC [nTPM]":"132.2","Brain RNA - amygdala [nTPM]":"127.6","Brain RNA - basal ganglia [nTPM]":"134.7","Brain RNA - cerebellum [nTPM]":"131.2","Brain RNA - cerebral cortex [nTPM]":"168.4","Brain RNA - hippocampal formation [nTPM]":"127.8","Brain RNA - hypothalamus [nTPM]":"137.5","Brain RNA - medulla oblongata [nTPM]":"133.9","Brain RNA - midbrain [nTPM]":"130.9","Brain RNA - pons [nTPM]":"134.1","Brain RNA - spinal cord [nTPM]":"128.7","Brain RNA - thalamus [nTPM]":"137.8","Brain RNA - white matter [nTPM]":"134.7","Single Cell Type RNA - Adipocytes [nTPM]":"84.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"91.2","Single Cell Type RNA - Astrocytes [nTPM]":"30.0","Single Cell Type RNA - B-cells [nTPM]":"58.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"55.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"91.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"179.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"82.6","Single Cell Type RNA - Bipolar cells [nTPM]":"54.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"130.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"162.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"154.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"128.7","Single Cell Type RNA - Club cells [nTPM]":"127.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"196.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"172.9","Single Cell Type RNA - dendritic cells [nTPM]":"48.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"292.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"508.7","Single Cell Type RNA - Ductal cells [nTPM]":"70.6","Single Cell Type RNA - Early spermatids [nTPM]":"13.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"125.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"116.5","Single Cell Type RNA - Endothelial cells [nTPM]":"66.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"121.3","Single Cell Type RNA - Erythroid cells [nTPM]":"56.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"105.3","Single Cell Type RNA - Fibroblasts [nTPM]":"88.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"99.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"114.1","Single Cell Type RNA - granulocytes [nTPM]":"57.1","Single Cell Type RNA - Granulosa cells [nTPM]":"97.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"83.2","Single Cell Type RNA - Hepatocytes [nTPM]":"250.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"136.7","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"186.3","Single Cell Type RNA - Ionocytes [nTPM]":"187.2","Single Cell Type RNA - Kupffer cells [nTPM]":"85.3","Single Cell Type RNA - Langerhans cells [nTPM]":"59.6","Single Cell Type RNA - Late spermatids [nTPM]":"16.5","Single Cell Type RNA - Leydig cells [nTPM]":"103.2","Single Cell Type RNA - Macrophages [nTPM]":"66.2","Single Cell Type RNA - Melanocytes [nTPM]":"136.9","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"79.6","Single Cell Type RNA - Muller glia cells [nTPM]":"168.8","Single Cell Type RNA - NK-cells [nTPM]":"51.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.7","Single Cell Type RNA - Paneth cells [nTPM]":"143.6","Single Cell Type RNA - Peritubular cells [nTPM]":"124.1","Single Cell Type RNA - Plasma cells [nTPM]":"74.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"93.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"162.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"326.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"148.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.6","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"128.6","Single Cell Type RNA - Spermatocytes [nTPM]":"42.5","Single Cell Type RNA - Spermatogonia [nTPM]":"50.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"113.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"62.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"77.3","Single Cell Type RNA - T-cells [nTPM]":"52.5","Single Cell Type RNA - Theca cells [nTPM]":"97.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"228.1","Single Cell Type RNA - Urothelial cells [nTPM]":"117.5"},{"Gene":"PNKP","Gene synonym":["PNK"],"Ensembl":"ENSG00000039650","Gene description":"Polynucleotide kinase 3'-phosphatase","Uniprot":["Q96T60"],"Chromosome":"19","Position":"49859882-49878351","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Hydrolase","Kinase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Neurodegeneration","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006782"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA006782":"AB_1855496"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.18e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"45.1","Tissue RNA - amygdala [nTPM]":"12.0","Tissue RNA - appendix [nTPM]":"21.0","Tissue RNA - basal ganglia [nTPM]":"12.9","Tissue RNA - bone marrow [nTPM]":"26.4","Tissue RNA - breast [nTPM]":"21.2","Tissue RNA - cerebellum [nTPM]":"12.8","Tissue RNA - cerebral cortex [nTPM]":"16.2","Tissue RNA - cervix [nTPM]":"21.1","Tissue RNA - choroid plexus [nTPM]":"24.2","Tissue RNA - colon [nTPM]":"21.6","Tissue RNA - duodenum [nTPM]":"16.0","Tissue RNA - endometrium 1 [nTPM]":"21.3","Tissue RNA - epididymis [nTPM]":"13.5","Tissue RNA - esophagus [nTPM]":"19.4","Tissue RNA - fallopian tube [nTPM]":"22.9","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"23.9","Tissue RNA - hippocampal formation [nTPM]":"14.4","Tissue RNA - hypothalamus [nTPM]":"11.9","Tissue RNA - kidney [nTPM]":"27.3","Tissue RNA - liver [nTPM]":"22.4","Tissue RNA - lung [nTPM]":"22.2","Tissue RNA - lymph node [nTPM]":"17.5","Tissue RNA - medulla oblongata [nTPM]":"14.0","Tissue RNA - midbrain [nTPM]":"14.0","Tissue RNA - ovary [nTPM]":"23.7","Tissue RNA - pancreas [nTPM]":"28.6","Tissue RNA - parathyroid gland [nTPM]":"16.7","Tissue RNA - pituitary gland [nTPM]":"36.8","Tissue RNA - placenta [nTPM]":"11.1","Tissue RNA - pons [nTPM]":"14.3","Tissue RNA - prostate [nTPM]":"25.3","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"21.6","Tissue RNA - seminal vesicle [nTPM]":"12.4","Tissue RNA - skeletal muscle [nTPM]":"18.5","Tissue RNA - skin 1 [nTPM]":"17.8","Tissue RNA - small intestine [nTPM]":"22.8","Tissue RNA - smooth muscle [nTPM]":"11.5","Tissue RNA - spinal cord [nTPM]":"12.8","Tissue RNA - spleen [nTPM]":"37.2","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"21.2","Tissue RNA - thalamus [nTPM]":"13.3","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"31.9","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"15.3","Tissue RNA - urinary bladder [nTPM]":"19.4","Tissue RNA - vagina [nTPM]":"18.0","Tissue RNA - white matter [nTPM]":"14.1","Cell RNA - A-431 [nTPM]":"27.5","Cell RNA - A549 [nTPM]":"17.4","Cell RNA - AF22 [nTPM]":"19.1","Cell RNA - AN3-CA [nTPM]":"27.2","Cell RNA - ASC diff [nTPM]":"15.8","Cell RNA - ASC TERT1 [nTPM]":"13.4","Cell RNA - BEWO [nTPM]":"28.6","Cell RNA - BJ [nTPM]":"43.4","Cell RNA - BJ hTERT+ [nTPM]":"21.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.7","Cell RNA - CACO-2 [nTPM]":"17.5","Cell RNA - CAPAN-2 [nTPM]":"34.2","Cell RNA - Daudi [nTPM]":"18.4","Cell RNA - EFO-21 [nTPM]":"13.6","Cell RNA - fHDF\/TERT166 [nTPM]":"13.6","Cell RNA - GAMG [nTPM]":"11.3","Cell RNA - HaCaT [nTPM]":"23.5","Cell RNA - HAP1 [nTPM]":"6.1","Cell RNA - HBEC3-KT [nTPM]":"25.9","Cell RNA - HBF TERT88 [nTPM]":"10.9","Cell RNA - HDLM-2 [nTPM]":"22.3","Cell RNA - HEK 293 [nTPM]":"27.2","Cell RNA - HEL [nTPM]":"30.0","Cell RNA - HeLa [nTPM]":"36.7","Cell RNA - Hep G2 [nTPM]":"14.8","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"25.8","Cell RNA - HMC-1 [nTPM]":"36.3","Cell RNA - HSkMC [nTPM]":"13.2","Cell RNA - hTCEpi [nTPM]":"13.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.9","Cell RNA - hTERT-HME1 [nTPM]":"11.0","Cell RNA - hTERT-RPE1 [nTPM]":"16.9","Cell RNA - HUVEC TERT2 [nTPM]":"26.3","Cell RNA - JURKAT [nTPM]":"23.4","Cell RNA - K-562 [nTPM]":"14.9","Cell RNA - Karpas-707 [nTPM]":"34.3","Cell RNA - LHCN-M2 [nTPM]":"24.7","Cell RNA - MCF7 [nTPM]":"18.8","Cell RNA - MOLT-4 [nTPM]":"28.7","Cell RNA - NB-4 [nTPM]":"23.5","Cell RNA - NTERA-2 [nTPM]":"16.0","Cell RNA - OE19 [nTPM]":"28.3","Cell RNA - PC-3 [nTPM]":"37.4","Cell RNA - REH [nTPM]":"24.3","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"34.7","Cell RNA - RPTEC TERT1 [nTPM]":"21.0","Cell RNA - RT4 [nTPM]":"68.5","Cell RNA - SCLC-21H [nTPM]":"20.6","Cell RNA - SH-SY5Y [nTPM]":"33.4","Cell RNA - SiHa [nTPM]":"19.3","Cell RNA - SK-BR-3 [nTPM]":"52.5","Cell RNA - SK-MEL-30 [nTPM]":"9.2","Cell RNA - SuSa [nTPM]":"14.5","Cell RNA - T-47d [nTPM]":"10.2","Cell RNA - THP-1 [nTPM]":"14.8","Cell RNA - TIME [nTPM]":"36.0","Cell RNA - U-138 MG [nTPM]":"37.6","Cell RNA - U-2 OS [nTPM]":"24.9","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"35.8","Cell RNA - U-266\/70 [nTPM]":"38.7","Cell RNA - U-266\/84 [nTPM]":"16.5","Cell RNA - U-698 [nTPM]":"13.0","Cell RNA - U-87 MG [nTPM]":"33.8","Cell RNA - U-937 [nTPM]":"12.3","Cell RNA - WM-115 [nTPM]":"30.8","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"12.3","Blood RNA - eosinophil [nTPM]":"16.7","Blood RNA - gdT-cell [nTPM]":"9.2","Blood RNA - intermediate monocyte [nTPM]":"11.5","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"9.1","Blood RNA - memory CD4 T-cell [nTPM]":"7.8","Blood RNA - memory CD8 T-cell [nTPM]":"7.3","Blood RNA - myeloid DC [nTPM]":"9.8","Blood RNA - naive B-cell [nTPM]":"12.2","Blood RNA - naive CD4 T-cell [nTPM]":"5.7","Blood RNA - naive CD8 T-cell [nTPM]":"5.0","Blood RNA - neutrophil [nTPM]":"23.4","Blood RNA - NK-cell [nTPM]":"3.9","Blood RNA - non-classical monocyte [nTPM]":"18.1","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"9.1","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"12.0","Brain RNA - basal ganglia [nTPM]":"12.9","Brain RNA - cerebellum [nTPM]":"12.8","Brain RNA - cerebral cortex [nTPM]":"16.2","Brain RNA - hippocampal formation [nTPM]":"14.4","Brain RNA - hypothalamus [nTPM]":"11.9","Brain RNA - medulla oblongata [nTPM]":"14.0","Brain RNA - midbrain [nTPM]":"14.0","Brain RNA - pons [nTPM]":"14.3","Brain RNA - spinal cord [nTPM]":"12.8","Brain RNA - thalamus [nTPM]":"13.3","Brain RNA - white matter [nTPM]":"14.1","Single Cell Type RNA - Adipocytes [nTPM]":"23.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"47.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"40.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"19.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"81.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.5","Single Cell Type RNA - dendritic cells [nTPM]":"37.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"42.5","Single Cell Type RNA - Early spermatids [nTPM]":"15.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.5","Single Cell Type RNA - Endothelial cells [nTPM]":"26.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.5","Single Cell Type RNA - Erythroid cells [nTPM]":"17.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"39.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.1","Single Cell Type RNA - Fibroblasts [nTPM]":"19.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.0","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"54.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.0","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.5","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"27.7","Single Cell Type RNA - Langerhans cells [nTPM]":"19.0","Single Cell Type RNA - Late spermatids [nTPM]":"32.9","Single Cell Type RNA - Leydig cells [nTPM]":"59.4","Single Cell Type RNA - Macrophages [nTPM]":"26.8","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"46.1","Single Cell Type RNA - Muller glia cells [nTPM]":"18.4","Single Cell Type RNA - NK-cells [nTPM]":"96.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.6","Single Cell Type RNA - Paneth cells [nTPM]":"22.3","Single Cell Type RNA - Peritubular cells [nTPM]":"44.8","Single Cell Type RNA - Plasma cells [nTPM]":"40.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.1","Single Cell Type RNA - Spermatocytes [nTPM]":"19.4","Single Cell Type RNA - Spermatogonia [nTPM]":"28.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.3","Single Cell Type RNA - T-cells [nTPM]":"39.2","Single Cell Type RNA - Theca cells [nTPM]":"83.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.1","Single Cell Type RNA - Urothelial cells [nTPM]":"35.6"},{"Gene":"PNPLA6","Gene synonym":["iPLA2delta","NTE","SPG39","sws"],"Ensembl":"ENSG00000032444","Gene description":"Patatin like phospholipase domain containing 6","Uniprot":["Q8IY17"],"Chromosome":"19","Position":"7534004-7561764","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Dwarfism","Hereditary spastic paraplegia","Hypogonadotropic hypogonadism","Mental retardation","Neurodegeneration","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"73.4","Late spermatids":"106.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007522","HPA064773"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007522":"AB_1079649","HPA064773":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.51e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.9","Tissue RNA - adrenal gland [nTPM]":"27.3","Tissue RNA - amygdala [nTPM]":"18.3","Tissue RNA - appendix [nTPM]":"26.2","Tissue RNA - basal ganglia [nTPM]":"23.2","Tissue RNA - bone marrow [nTPM]":"26.1","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"31.5","Tissue RNA - cervix [nTPM]":"20.2","Tissue RNA - choroid plexus [nTPM]":"12.6","Tissue RNA - colon [nTPM]":"25.7","Tissue RNA - duodenum [nTPM]":"26.9","Tissue RNA - endometrium 1 [nTPM]":"20.8","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"20.4","Tissue RNA - fallopian tube [nTPM]":"16.8","Tissue RNA - gallbladder [nTPM]":"13.7","Tissue RNA - heart muscle [nTPM]":"20.7","Tissue RNA - hippocampal formation [nTPM]":"21.9","Tissue RNA - hypothalamus [nTPM]":"16.3","Tissue RNA - kidney [nTPM]":"25.6","Tissue RNA - liver [nTPM]":"21.9","Tissue RNA - lung [nTPM]":"40.4","Tissue RNA - lymph node [nTPM]":"19.5","Tissue RNA - medulla oblongata [nTPM]":"23.4","Tissue RNA - midbrain [nTPM]":"20.3","Tissue RNA - ovary [nTPM]":"18.8","Tissue RNA - pancreas [nTPM]":"16.4","Tissue RNA - parathyroid gland [nTPM]":"15.6","Tissue RNA - pituitary gland [nTPM]":"32.7","Tissue RNA - placenta [nTPM]":"13.6","Tissue RNA - pons [nTPM]":"25.6","Tissue RNA - prostate [nTPM]":"21.4","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"10.6","Tissue RNA - salivary gland [nTPM]":"15.8","Tissue RNA - seminal vesicle [nTPM]":"12.8","Tissue RNA - skeletal muscle [nTPM]":"33.5","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"29.6","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"41.9","Tissue RNA - stomach 1 [nTPM]":"19.2","Tissue RNA - testis [nTPM]":"36.4","Tissue RNA - thalamus [nTPM]":"23.7","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"22.7","Tissue RNA - tongue [nTPM]":"19.5","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"24.6","Tissue RNA - vagina [nTPM]":"17.4","Tissue RNA - white matter [nTPM]":"23.6","Cell RNA - A-431 [nTPM]":"32.4","Cell RNA - A549 [nTPM]":"80.1","Cell RNA - AF22 [nTPM]":"14.7","Cell RNA - AN3-CA [nTPM]":"36.1","Cell RNA - ASC diff [nTPM]":"25.5","Cell RNA - ASC TERT1 [nTPM]":"37.0","Cell RNA - BEWO [nTPM]":"34.3","Cell RNA - BJ [nTPM]":"42.2","Cell RNA - BJ hTERT+ [nTPM]":"41.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.8","Cell RNA - CACO-2 [nTPM]":"18.6","Cell RNA - CAPAN-2 [nTPM]":"43.7","Cell RNA - Daudi [nTPM]":"27.3","Cell RNA - EFO-21 [nTPM]":"69.1","Cell RNA - fHDF\/TERT166 [nTPM]":"55.3","Cell RNA - GAMG [nTPM]":"19.7","Cell RNA - HaCaT [nTPM]":"40.8","Cell RNA - HAP1 [nTPM]":"13.1","Cell RNA - HBEC3-KT [nTPM]":"39.4","Cell RNA - HBF TERT88 [nTPM]":"16.3","Cell RNA - HDLM-2 [nTPM]":"68.5","Cell RNA - HEK 293 [nTPM]":"29.2","Cell RNA - HEL [nTPM]":"17.7","Cell RNA - HeLa [nTPM]":"41.8","Cell RNA - Hep G2 [nTPM]":"13.9","Cell RNA - HHSteC [nTPM]":"29.2","Cell RNA - HL-60 [nTPM]":"20.2","Cell RNA - HMC-1 [nTPM]":"53.0","Cell RNA - HSkMC [nTPM]":"31.6","Cell RNA - hTCEpi [nTPM]":"22.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.8","Cell RNA - hTERT-HME1 [nTPM]":"23.8","Cell RNA - hTERT-RPE1 [nTPM]":"49.2","Cell RNA - HUVEC TERT2 [nTPM]":"62.7","Cell RNA - JURKAT [nTPM]":"31.4","Cell RNA - K-562 [nTPM]":"14.9","Cell RNA - Karpas-707 [nTPM]":"36.5","Cell RNA - LHCN-M2 [nTPM]":"28.6","Cell RNA - MCF7 [nTPM]":"15.7","Cell RNA - MOLT-4 [nTPM]":"22.2","Cell RNA - NB-4 [nTPM]":"26.0","Cell RNA - NTERA-2 [nTPM]":"16.2","Cell RNA - OE19 [nTPM]":"15.5","Cell RNA - PC-3 [nTPM]":"71.7","Cell RNA - REH [nTPM]":"17.3","Cell RNA - RH-30 [nTPM]":"9.0","Cell RNA - RPMI-8226 [nTPM]":"31.9","Cell RNA - RPTEC TERT1 [nTPM]":"27.9","Cell RNA - RT4 [nTPM]":"31.2","Cell RNA - SCLC-21H [nTPM]":"19.0","Cell RNA - SH-SY5Y [nTPM]":"32.5","Cell RNA - SiHa [nTPM]":"34.9","Cell RNA - SK-BR-3 [nTPM]":"15.7","Cell RNA - SK-MEL-30 [nTPM]":"45.6","Cell RNA - SuSa [nTPM]":"20.4","Cell RNA - T-47d [nTPM]":"14.1","Cell RNA - THP-1 [nTPM]":"27.6","Cell RNA - TIME [nTPM]":"67.0","Cell RNA - U-138 MG [nTPM]":"38.5","Cell RNA - U-2 OS [nTPM]":"22.1","Cell RNA - U-2197 [nTPM]":"53.3","Cell RNA - U-251 MG [nTPM]":"44.2","Cell RNA - U-266\/70 [nTPM]":"42.6","Cell RNA - U-266\/84 [nTPM]":"30.1","Cell RNA - U-698 [nTPM]":"12.2","Cell RNA - U-87 MG [nTPM]":"64.2","Cell RNA - U-937 [nTPM]":"23.2","Cell RNA - WM-115 [nTPM]":"36.7","Blood RNA - basophil [nTPM]":"15.7","Blood RNA - classical monocyte [nTPM]":"11.3","Blood RNA - eosinophil [nTPM]":"37.6","Blood RNA - gdT-cell [nTPM]":"5.4","Blood RNA - intermediate monocyte [nTPM]":"20.0","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"6.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.7","Blood RNA - myeloid DC [nTPM]":"12.1","Blood RNA - naive B-cell [nTPM]":"4.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"7.9","Blood RNA - non-classical monocyte [nTPM]":"35.0","Blood RNA - plasmacytoid DC [nTPM]":"3.8","Blood RNA - T-reg [nTPM]":"6.9","Blood RNA - total PBMC [nTPM]":"8.8","Brain RNA - amygdala [nTPM]":"18.3","Brain RNA - basal ganglia [nTPM]":"23.2","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"31.5","Brain RNA - hippocampal formation [nTPM]":"21.9","Brain RNA - hypothalamus [nTPM]":"16.3","Brain RNA - medulla oblongata [nTPM]":"23.4","Brain RNA - midbrain [nTPM]":"20.3","Brain RNA - pons [nTPM]":"25.6","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"23.7","Brain RNA - white matter [nTPM]":"23.6","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"11.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"10.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.2","Single Cell Type RNA - dendritic cells [nTPM]":"14.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"48.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.8","Single Cell Type RNA - Early spermatids [nTPM]":"73.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.4","Single Cell Type RNA - Erythroid cells [nTPM]":"25.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"19.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"20.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.4","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"68.3","Single Cell Type RNA - Langerhans cells [nTPM]":"16.0","Single Cell Type RNA - Late spermatids [nTPM]":"106.1","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"42.4","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"23.6","Single Cell Type RNA - Muller glia cells [nTPM]":"9.2","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"17.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"67.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"60.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"10.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"PNPO","Gene synonym":["PDXPO"],"Ensembl":"ENSG00000108439","Gene description":"Pyridoxamine 5'-phosphate oxidase","Uniprot":["Q9NVS9"],"Chromosome":"17","Position":"47941506-47949308","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pyridoxine biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"88.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"62.6","Hepatocytes":"53.4","Proximal tubular cells":"86.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023204","HPA027776"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023204":"AB_1855506","HPA027776":"AB_10601246"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"15.8","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"15.9","Tissue RNA - bone marrow [nTPM]":"3.5","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"16.7","Tissue RNA - cerebral cortex [nTPM]":"22.0","Tissue RNA - cervix [nTPM]":"7.0","Tissue RNA - choroid plexus [nTPM]":"12.9","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"5.0","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"10.1","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"16.0","Tissue RNA - hypothalamus [nTPM]":"21.9","Tissue RNA - kidney [nTPM]":"35.1","Tissue RNA - liver [nTPM]":"88.8","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"19.1","Tissue RNA - midbrain [nTPM]":"21.2","Tissue RNA - ovary [nTPM]":"5.8","Tissue RNA - pancreas [nTPM]":"10.9","Tissue RNA - parathyroid gland [nTPM]":"26.6","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"20.6","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"10.4","Tissue RNA - seminal vesicle [nTPM]":"7.8","Tissue RNA - skeletal muscle [nTPM]":"21.1","Tissue RNA - skin 1 [nTPM]":"6.7","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"16.5","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"20.6","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"17.8","Tissue RNA - tongue [nTPM]":"19.6","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"37.9","Cell RNA - A549 [nTPM]":"30.9","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"5.8","Cell RNA - ASC diff [nTPM]":"15.3","Cell RNA - ASC TERT1 [nTPM]":"11.7","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"12.2","Cell RNA - BJ hTERT+ [nTPM]":"7.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.9","Cell RNA - CACO-2 [nTPM]":"51.1","Cell RNA - CAPAN-2 [nTPM]":"27.6","Cell RNA - Daudi [nTPM]":"35.2","Cell RNA - EFO-21 [nTPM]":"57.4","Cell RNA - fHDF\/TERT166 [nTPM]":"12.7","Cell RNA - GAMG [nTPM]":"5.5","Cell RNA - HaCaT [nTPM]":"22.0","Cell RNA - HAP1 [nTPM]":"19.4","Cell RNA - HBEC3-KT [nTPM]":"34.7","Cell RNA - HBF TERT88 [nTPM]":"20.3","Cell RNA - HDLM-2 [nTPM]":"43.4","Cell RNA - HEK 293 [nTPM]":"16.4","Cell RNA - HEL [nTPM]":"24.6","Cell RNA - HeLa [nTPM]":"13.9","Cell RNA - Hep G2 [nTPM]":"53.6","Cell RNA - HHSteC [nTPM]":"16.3","Cell RNA - HL-60 [nTPM]":"22.6","Cell RNA - HMC-1 [nTPM]":"16.6","Cell RNA - HSkMC [nTPM]":"15.4","Cell RNA - hTCEpi [nTPM]":"26.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.8","Cell RNA - hTERT-HME1 [nTPM]":"32.7","Cell RNA - hTERT-RPE1 [nTPM]":"13.1","Cell RNA - HUVEC TERT2 [nTPM]":"18.0","Cell RNA - JURKAT [nTPM]":"26.1","Cell RNA - K-562 [nTPM]":"24.4","Cell RNA - Karpas-707 [nTPM]":"12.2","Cell RNA - LHCN-M2 [nTPM]":"16.5","Cell RNA - MCF7 [nTPM]":"28.3","Cell RNA - MOLT-4 [nTPM]":"25.3","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"4.5","Cell RNA - OE19 [nTPM]":"37.4","Cell RNA - PC-3 [nTPM]":"37.1","Cell RNA - REH [nTPM]":"18.8","Cell RNA - RH-30 [nTPM]":"10.4","Cell RNA - RPMI-8226 [nTPM]":"26.2","Cell RNA - RPTEC TERT1 [nTPM]":"40.2","Cell RNA - RT4 [nTPM]":"19.5","Cell RNA - SCLC-21H [nTPM]":"12.1","Cell RNA - SH-SY5Y [nTPM]":"9.5","Cell RNA - SiHa [nTPM]":"11.2","Cell RNA - SK-BR-3 [nTPM]":"18.6","Cell RNA - SK-MEL-30 [nTPM]":"10.7","Cell RNA - SuSa [nTPM]":"8.5","Cell RNA - T-47d [nTPM]":"32.4","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"19.1","Cell RNA - U-138 MG [nTPM]":"22.6","Cell RNA - U-2 OS [nTPM]":"12.8","Cell RNA - U-2197 [nTPM]":"22.2","Cell RNA - U-251 MG [nTPM]":"26.2","Cell RNA - U-266\/70 [nTPM]":"27.8","Cell RNA - U-266\/84 [nTPM]":"34.0","Cell RNA - U-698 [nTPM]":"19.0","Cell RNA - U-87 MG [nTPM]":"18.4","Cell RNA - U-937 [nTPM]":"19.2","Cell RNA - WM-115 [nTPM]":"11.7","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"12.3","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"7.2","Blood RNA - intermediate monocyte [nTPM]":"17.7","Blood RNA - MAIT T-cell [nTPM]":"8.2","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"7.6","Blood RNA - myeloid DC [nTPM]":"13.5","Blood RNA - naive B-cell [nTPM]":"5.3","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.1","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"7.9","Blood RNA - non-classical monocyte [nTPM]":"11.9","Blood RNA - plasmacytoid DC [nTPM]":"9.8","Blood RNA - T-reg [nTPM]":"7.0","Blood RNA - total PBMC [nTPM]":"10.3","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"15.9","Brain RNA - cerebellum [nTPM]":"16.7","Brain RNA - cerebral cortex [nTPM]":"22.0","Brain RNA - hippocampal formation [nTPM]":"16.0","Brain RNA - hypothalamus [nTPM]":"21.9","Brain RNA - medulla oblongata [nTPM]":"19.1","Brain RNA - midbrain [nTPM]":"21.2","Brain RNA - pons [nTPM]":"20.6","Brain RNA - spinal cord [nTPM]":"16.5","Brain RNA - thalamus [nTPM]":"20.6","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"7.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.9","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.4","Single Cell Type RNA - dendritic cells [nTPM]":"7.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"62.6","Single Cell Type RNA - Ductal cells [nTPM]":"18.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.4","Single Cell Type RNA - Endothelial cells [nTPM]":"5.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"53.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"11.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"10.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"8.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.0","Single Cell Type RNA - Paneth cells [nTPM]":"8.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"19.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.4","Single Cell Type RNA - Urothelial cells [nTPM]":"5.0"},{"Gene":"POC1B","Gene synonym":["FLJ14923","TUWD12","WDR51B"],"Ensembl":"ENSG00000139323","Gene description":"POC1 centriolar protein B","Uniprot":["Q8TC44"],"Chromosome":"12","Position":"89419718-89526047","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"73.2","Late spermatids":"96.3","Oligodendrocytes":"99.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.59e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.45e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.0","Tissue RNA - adrenal gland [nTPM]":"5.6","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"8.0","Tissue RNA - cerebellum [nTPM]":"9.7","Tissue RNA - cerebral cortex [nTPM]":"11.2","Tissue RNA - cervix [nTPM]":"11.4","Tissue RNA - choroid plexus [nTPM]":"6.0","Tissue RNA - colon [nTPM]":"12.6","Tissue RNA - duodenum [nTPM]":"11.9","Tissue RNA - endometrium 1 [nTPM]":"8.7","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"12.3","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"7.5","Tissue RNA - hypothalamus [nTPM]":"9.1","Tissue RNA - kidney [nTPM]":"11.9","Tissue RNA - liver [nTPM]":"8.0","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"7.9","Tissue RNA - medulla oblongata [nTPM]":"10.3","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"7.3","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"12.8","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"8.0","Tissue RNA - seminal vesicle [nTPM]":"6.3","Tissue RNA - skeletal muscle [nTPM]":"4.9","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"12.7","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"8.9","Tissue RNA - stomach 1 [nTPM]":"10.9","Tissue RNA - testis [nTPM]":"7.2","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"7.6","Tissue RNA - thyroid gland [nTPM]":"8.1","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"8.4","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"14.1","Cell RNA - A-431 [nTPM]":"13.4","Cell RNA - A549 [nTPM]":"12.0","Cell RNA - AF22 [nTPM]":"12.2","Cell RNA - AN3-CA [nTPM]":"21.6","Cell RNA - ASC diff [nTPM]":"12.3","Cell RNA - ASC TERT1 [nTPM]":"9.6","Cell RNA - BEWO [nTPM]":"8.5","Cell RNA - BJ [nTPM]":"13.3","Cell RNA - BJ hTERT+ [nTPM]":"12.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.4","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"6.1","Cell RNA - Daudi [nTPM]":"5.3","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.2","Cell RNA - GAMG [nTPM]":"11.2","Cell RNA - HaCaT [nTPM]":"10.2","Cell RNA - HAP1 [nTPM]":"10.6","Cell RNA - HBEC3-KT [nTPM]":"15.4","Cell RNA - HBF TERT88 [nTPM]":"16.1","Cell RNA - HDLM-2 [nTPM]":"17.9","Cell RNA - HEK 293 [nTPM]":"9.2","Cell RNA - HEL [nTPM]":"11.3","Cell RNA - HeLa [nTPM]":"4.0","Cell RNA - Hep G2 [nTPM]":"9.2","Cell RNA - HHSteC [nTPM]":"7.2","Cell RNA - HL-60 [nTPM]":"17.5","Cell RNA - HMC-1 [nTPM]":"13.1","Cell RNA - HSkMC [nTPM]":"6.4","Cell RNA - hTCEpi [nTPM]":"10.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.3","Cell RNA - hTERT-HME1 [nTPM]":"21.9","Cell RNA - hTERT-RPE1 [nTPM]":"25.6","Cell RNA - HUVEC TERT2 [nTPM]":"21.7","Cell RNA - JURKAT [nTPM]":"19.6","Cell RNA - K-562 [nTPM]":"11.9","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"13.5","Cell RNA - MCF7 [nTPM]":"8.9","Cell RNA - MOLT-4 [nTPM]":"13.2","Cell RNA - NB-4 [nTPM]":"17.0","Cell RNA - NTERA-2 [nTPM]":"5.9","Cell RNA - OE19 [nTPM]":"25.1","Cell RNA - PC-3 [nTPM]":"30.8","Cell RNA - REH [nTPM]":"15.3","Cell RNA - RH-30 [nTPM]":"12.9","Cell RNA - RPMI-8226 [nTPM]":"15.1","Cell RNA - RPTEC TERT1 [nTPM]":"17.0","Cell RNA - RT4 [nTPM]":"16.1","Cell RNA - SCLC-21H [nTPM]":"11.2","Cell RNA - SH-SY5Y [nTPM]":"12.1","Cell RNA - SiHa [nTPM]":"10.3","Cell RNA - SK-BR-3 [nTPM]":"15.7","Cell RNA - SK-MEL-30 [nTPM]":"18.9","Cell RNA - SuSa [nTPM]":"14.7","Cell RNA - T-47d [nTPM]":"24.6","Cell RNA - THP-1 [nTPM]":"8.0","Cell RNA - TIME [nTPM]":"12.9","Cell RNA - U-138 MG [nTPM]":"9.0","Cell RNA - U-2 OS [nTPM]":"3.1","Cell RNA - U-2197 [nTPM]":"12.7","Cell RNA - U-251 MG [nTPM]":"10.8","Cell RNA - U-266\/70 [nTPM]":"13.7","Cell RNA - U-266\/84 [nTPM]":"12.1","Cell RNA - U-698 [nTPM]":"12.5","Cell RNA - U-87 MG [nTPM]":"7.5","Cell RNA - U-937 [nTPM]":"14.6","Cell RNA - WM-115 [nTPM]":"10.1","Blood RNA - basophil [nTPM]":"12.1","Blood RNA - classical monocyte [nTPM]":"9.8","Blood RNA - eosinophil [nTPM]":"14.8","Blood RNA - gdT-cell [nTPM]":"15.0","Blood RNA - intermediate monocyte [nTPM]":"10.0","Blood RNA - MAIT T-cell [nTPM]":"19.2","Blood RNA - memory B-cell [nTPM]":"9.4","Blood RNA - memory CD4 T-cell [nTPM]":"10.6","Blood RNA - memory CD8 T-cell [nTPM]":"13.2","Blood RNA - myeloid DC [nTPM]":"8.9","Blood RNA - naive B-cell [nTPM]":"10.4","Blood RNA - naive CD4 T-cell [nTPM]":"8.5","Blood RNA - naive CD8 T-cell [nTPM]":"11.6","Blood RNA - neutrophil [nTPM]":"10.3","Blood RNA - NK-cell [nTPM]":"18.9","Blood RNA - non-classical monocyte [nTPM]":"9.4","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"10.6","Blood RNA - total PBMC [nTPM]":"11.1","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"9.7","Brain RNA - cerebral cortex [nTPM]":"11.2","Brain RNA - hippocampal formation [nTPM]":"7.5","Brain RNA - hypothalamus [nTPM]":"9.1","Brain RNA - medulla oblongata [nTPM]":"10.3","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"14.1","Single Cell Type RNA - Adipocytes [nTPM]":"8.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.4","Single Cell Type RNA - Astrocytes [nTPM]":"30.7","Single Cell Type RNA - B-cells [nTPM]":"15.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"18.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.8","Single Cell Type RNA - dendritic cells [nTPM]":"19.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"9.2","Single Cell Type RNA - Early spermatids [nTPM]":"60.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"53.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.4","Single Cell Type RNA - Endothelial cells [nTPM]":"10.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"22.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"73.2","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"9.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"6.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.1","Single Cell Type RNA - Langerhans cells [nTPM]":"17.7","Single Cell Type RNA - Late spermatids [nTPM]":"96.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"11.2","Single Cell Type RNA - Muller glia cells [nTPM]":"6.9","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"99.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.2","Single Cell Type RNA - Paneth cells [nTPM]":"14.8","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.0","Single Cell Type RNA - Spermatocytes [nTPM]":"14.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"20.1","Single Cell Type RNA - Theca cells [nTPM]":"6.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.2","Single Cell Type RNA - Urothelial cells [nTPM]":"22.2"},{"Gene":"POLG","Gene synonym":["POLG1","POLGA"],"Ensembl":"ENSG00000140521","Gene description":"DNA polymerase gamma, catalytic subunit","Uniprot":["P54098"],"Chromosome":"15","Position":"89305198-89334861","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA replication"],"Molecular function":["DNA-binding","DNA-directed DNA polymerase","Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Leigh syndrome","Neurodegeneration","Neuropathy","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056821","HPA078482"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA056821":"AB_2683247","HPA078482":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.73e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.3","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"12.0","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"12.0","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"13.3","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"12.9","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"14.6","Tissue RNA - fallopian tube [nTPM]":"11.2","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"13.8","Tissue RNA - hippocampal formation [nTPM]":"6.1","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"10.1","Tissue RNA - liver [nTPM]":"12.9","Tissue RNA - lung [nTPM]":"13.8","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"10.8","Tissue RNA - pancreas [nTPM]":"10.7","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"10.5","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"12.3","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"25.0","Tissue RNA - skin 1 [nTPM]":"16.0","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"16.2","Tissue RNA - stomach 1 [nTPM]":"11.9","Tissue RNA - testis [nTPM]":"5.4","Tissue RNA - thalamus [nTPM]":"5.7","Tissue RNA - thymus [nTPM]":"7.3","Tissue RNA - thyroid gland [nTPM]":"10.5","Tissue RNA - tongue [nTPM]":"10.9","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"12.2","Tissue RNA - vagina [nTPM]":"12.7","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"17.0","Cell RNA - AF22 [nTPM]":"6.7","Cell RNA - AN3-CA [nTPM]":"10.0","Cell RNA - ASC diff [nTPM]":"7.7","Cell RNA - ASC TERT1 [nTPM]":"1.6","Cell RNA - BEWO [nTPM]":"16.4","Cell RNA - BJ [nTPM]":"16.4","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.9","Cell RNA - CACO-2 [nTPM]":"28.0","Cell RNA - CAPAN-2 [nTPM]":"10.9","Cell RNA - Daudi [nTPM]":"14.4","Cell RNA - EFO-21 [nTPM]":"33.6","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"16.9","Cell RNA - HaCaT [nTPM]":"11.8","Cell RNA - HAP1 [nTPM]":"14.3","Cell RNA - HBEC3-KT [nTPM]":"4.8","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"35.8","Cell RNA - HEK 293 [nTPM]":"31.3","Cell RNA - HEL [nTPM]":"19.4","Cell RNA - HeLa [nTPM]":"19.5","Cell RNA - Hep G2 [nTPM]":"11.1","Cell RNA - HHSteC [nTPM]":"10.8","Cell RNA - HL-60 [nTPM]":"21.3","Cell RNA - HMC-1 [nTPM]":"33.6","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"8.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.0","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"8.3","Cell RNA - HUVEC TERT2 [nTPM]":"12.2","Cell RNA - JURKAT [nTPM]":"26.8","Cell RNA - K-562 [nTPM]":"19.5","Cell RNA - Karpas-707 [nTPM]":"5.4","Cell RNA - LHCN-M2 [nTPM]":"6.1","Cell RNA - MCF7 [nTPM]":"22.8","Cell RNA - MOLT-4 [nTPM]":"16.3","Cell RNA - NB-4 [nTPM]":"16.5","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"13.7","Cell RNA - PC-3 [nTPM]":"8.2","Cell RNA - REH [nTPM]":"18.2","Cell RNA - RH-30 [nTPM]":"13.7","Cell RNA - RPMI-8226 [nTPM]":"17.4","Cell RNA - RPTEC TERT1 [nTPM]":"3.2","Cell RNA - RT4 [nTPM]":"19.2","Cell RNA - SCLC-21H [nTPM]":"24.5","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"26.8","Cell RNA - SK-BR-3 [nTPM]":"9.6","Cell RNA - SK-MEL-30 [nTPM]":"16.8","Cell RNA - SuSa [nTPM]":"6.0","Cell RNA - T-47d [nTPM]":"7.7","Cell RNA - THP-1 [nTPM]":"10.8","Cell RNA - TIME [nTPM]":"17.3","Cell RNA - U-138 MG [nTPM]":"12.8","Cell RNA - U-2 OS [nTPM]":"15.6","Cell RNA - U-2197 [nTPM]":"28.5","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"17.0","Cell RNA - U-266\/84 [nTPM]":"9.4","Cell RNA - U-698 [nTPM]":"18.6","Cell RNA - U-87 MG [nTPM]":"9.5","Cell RNA - U-937 [nTPM]":"14.3","Cell RNA - WM-115 [nTPM]":"11.6","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"4.3","Blood RNA - eosinophil [nTPM]":"6.1","Blood RNA - gdT-cell [nTPM]":"5.5","Blood RNA - intermediate monocyte [nTPM]":"4.0","Blood RNA - MAIT T-cell [nTPM]":"4.3","Blood RNA - memory B-cell [nTPM]":"2.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.6","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"6.0","Blood RNA - naive B-cell [nTPM]":"3.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.4","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"5.0","Blood RNA - non-classical monocyte [nTPM]":"3.5","Blood RNA - plasmacytoid DC [nTPM]":"4.1","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"6.1","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"5.7","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"15.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.9","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"17.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"9.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.0","Single Cell Type RNA - dendritic cells [nTPM]":"33.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.4","Single Cell Type RNA - Endothelial cells [nTPM]":"12.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.8","Single Cell Type RNA - Fibroblasts [nTPM]":"11.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.3","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"14.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"17.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.7","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.9","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"14.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"17.2","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"21.8","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.4","Single Cell Type RNA - Paneth cells [nTPM]":"15.9","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"16.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"9.2","Single Cell Type RNA - Spermatogonia [nTPM]":"11.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - T-cells [nTPM]":"21.7","Single Cell Type RNA - Theca cells [nTPM]":"14.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.6","Single Cell Type RNA - Urothelial cells [nTPM]":"15.5"},{"Gene":"POLG2","Gene synonym":["HP55","MTPOLB"],"Ensembl":"ENSG00000256525","Gene description":"DNA polymerase gamma 2, accessory subunit","Uniprot":["Q9UHN1"],"Chromosome":"17","Position":"64477785-64497054","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["DNA replication"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"92.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017030","HPA023202","HPA078396"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB017030":null,"HPA023202":"AB_1855523","HPA078396":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.39e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.59e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"5.8","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"4.5","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"3.5","Tissue RNA - endometrium 1 [nTPM]":"4.7","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"5.0","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"5.3","Tissue RNA - lung [nTPM]":"3.9","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"7.9","Tissue RNA - pancreas [nTPM]":"4.7","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"2.9","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"1.9","Tissue RNA - retina [nTPM]":"2.6","Tissue RNA - salivary gland [nTPM]":"3.9","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"6.8","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"7.5","Tissue RNA - stomach 1 [nTPM]":"4.0","Tissue RNA - testis [nTPM]":"12.8","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"4.2","Tissue RNA - tonsil [nTPM]":"4.0","Tissue RNA - urinary bladder [nTPM]":"4.8","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"8.1","Cell RNA - A549 [nTPM]":"10.4","Cell RNA - AF22 [nTPM]":"6.7","Cell RNA - AN3-CA [nTPM]":"7.6","Cell RNA - ASC diff [nTPM]":"7.2","Cell RNA - ASC TERT1 [nTPM]":"4.7","Cell RNA - BEWO [nTPM]":"8.4","Cell RNA - BJ [nTPM]":"4.6","Cell RNA - BJ hTERT+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.9","Cell RNA - CACO-2 [nTPM]":"10.1","Cell RNA - CAPAN-2 [nTPM]":"6.2","Cell RNA - Daudi [nTPM]":"15.7","Cell RNA - EFO-21 [nTPM]":"5.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.8","Cell RNA - GAMG [nTPM]":"6.5","Cell RNA - HaCaT [nTPM]":"5.3","Cell RNA - HAP1 [nTPM]":"9.3","Cell RNA - HBEC3-KT [nTPM]":"3.9","Cell RNA - HBF TERT88 [nTPM]":"8.8","Cell RNA - HDLM-2 [nTPM]":"4.6","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"9.9","Cell RNA - HeLa [nTPM]":"12.2","Cell RNA - Hep G2 [nTPM]":"10.5","Cell RNA - HHSteC [nTPM]":"7.0","Cell RNA - HL-60 [nTPM]":"14.2","Cell RNA - HMC-1 [nTPM]":"10.6","Cell RNA - HSkMC [nTPM]":"4.5","Cell RNA - hTCEpi [nTPM]":"4.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.3","Cell RNA - hTERT-HME1 [nTPM]":"7.2","Cell RNA - hTERT-RPE1 [nTPM]":"8.4","Cell RNA - HUVEC TERT2 [nTPM]":"4.7","Cell RNA - JURKAT [nTPM]":"7.6","Cell RNA - K-562 [nTPM]":"18.3","Cell RNA - Karpas-707 [nTPM]":"4.7","Cell RNA - LHCN-M2 [nTPM]":"6.5","Cell RNA - MCF7 [nTPM]":"10.0","Cell RNA - MOLT-4 [nTPM]":"15.3","Cell RNA - NB-4 [nTPM]":"15.4","Cell RNA - NTERA-2 [nTPM]":"7.3","Cell RNA - OE19 [nTPM]":"8.6","Cell RNA - PC-3 [nTPM]":"11.2","Cell RNA - REH [nTPM]":"13.3","Cell RNA - RH-30 [nTPM]":"23.8","Cell RNA - RPMI-8226 [nTPM]":"14.2","Cell RNA - RPTEC TERT1 [nTPM]":"6.4","Cell RNA - RT4 [nTPM]":"2.4","Cell RNA - SCLC-21H [nTPM]":"9.3","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"4.4","Cell RNA - SK-BR-3 [nTPM]":"7.1","Cell RNA - SK-MEL-30 [nTPM]":"8.0","Cell RNA - SuSa [nTPM]":"8.7","Cell RNA - T-47d [nTPM]":"7.4","Cell RNA - THP-1 [nTPM]":"12.0","Cell RNA - TIME [nTPM]":"6.1","Cell RNA - U-138 MG [nTPM]":"7.0","Cell RNA - U-2 OS [nTPM]":"9.9","Cell RNA - U-2197 [nTPM]":"5.8","Cell RNA - U-251 MG [nTPM]":"12.3","Cell RNA - U-266\/70 [nTPM]":"8.4","Cell RNA - U-266\/84 [nTPM]":"7.2","Cell RNA - U-698 [nTPM]":"11.3","Cell RNA - U-87 MG [nTPM]":"5.9","Cell RNA - U-937 [nTPM]":"13.4","Cell RNA - WM-115 [nTPM]":"4.8","Blood RNA - basophil [nTPM]":"7.2","Blood RNA - classical monocyte [nTPM]":"5.2","Blood RNA - eosinophil [nTPM]":"6.0","Blood RNA - gdT-cell [nTPM]":"6.5","Blood RNA - intermediate monocyte [nTPM]":"3.2","Blood RNA - MAIT T-cell [nTPM]":"6.6","Blood RNA - memory B-cell [nTPM]":"10.7","Blood RNA - memory CD4 T-cell [nTPM]":"7.5","Blood RNA - memory CD8 T-cell [nTPM]":"6.2","Blood RNA - myeloid DC [nTPM]":"9.7","Blood RNA - naive B-cell [nTPM]":"11.9","Blood RNA - naive CD4 T-cell [nTPM]":"9.7","Blood RNA - naive CD8 T-cell [nTPM]":"9.7","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"5.8","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"24.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.2","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"19.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"13.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.0","Single Cell Type RNA - dendritic cells [nTPM]":"22.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"14.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.7","Single Cell Type RNA - Endothelial cells [nTPM]":"16.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.9","Single Cell Type RNA - Erythroid cells [nTPM]":"20.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.4","Single Cell Type RNA - Fibroblasts [nTPM]":"19.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.2","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"9.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"4.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.9","Single Cell Type RNA - Langerhans cells [nTPM]":"7.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"17.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"8.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.5","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.9","Single Cell Type RNA - Paneth cells [nTPM]":"21.8","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"92.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.4","Single Cell Type RNA - Spermatocytes [nTPM]":"49.7","Single Cell Type RNA - Spermatogonia [nTPM]":"9.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"16.2","Single Cell Type RNA - Theca cells [nTPM]":"15.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.8","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"POMGNT1","Gene synonym":["FLJ20277","LGMD2O","MEB","MGAT1.2"],"Ensembl":"ENSG00000085998","Gene description":"Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)","Uniprot":["Q8WZA1"],"Chromosome":"1","Position":"46188682-46220305","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044518"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044518":"AB_10795985"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.52e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.5","Tissue RNA - adrenal gland [nTPM]":"40.4","Tissue RNA - amygdala [nTPM]":"45.8","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"51.9","Tissue RNA - bone marrow [nTPM]":"5.5","Tissue RNA - breast [nTPM]":"23.7","Tissue RNA - cerebellum [nTPM]":"52.7","Tissue RNA - cerebral cortex [nTPM]":"50.4","Tissue RNA - cervix [nTPM]":"26.3","Tissue RNA - choroid plexus [nTPM]":"44.5","Tissue RNA - colon [nTPM]":"23.9","Tissue RNA - duodenum [nTPM]":"21.5","Tissue RNA - endometrium 1 [nTPM]":"24.1","Tissue RNA - epididymis [nTPM]":"31.1","Tissue RNA - esophagus [nTPM]":"18.7","Tissue RNA - fallopian tube [nTPM]":"26.2","Tissue RNA - gallbladder [nTPM]":"17.8","Tissue RNA - heart muscle [nTPM]":"83.3","Tissue RNA - hippocampal formation [nTPM]":"45.9","Tissue RNA - hypothalamus [nTPM]":"49.8","Tissue RNA - kidney [nTPM]":"36.5","Tissue RNA - liver [nTPM]":"40.7","Tissue RNA - lung [nTPM]":"24.0","Tissue RNA - lymph node [nTPM]":"13.6","Tissue RNA - medulla oblongata [nTPM]":"55.0","Tissue RNA - midbrain [nTPM]":"53.3","Tissue RNA - ovary [nTPM]":"21.9","Tissue RNA - pancreas [nTPM]":"29.5","Tissue RNA - parathyroid gland [nTPM]":"87.5","Tissue RNA - pituitary gland [nTPM]":"47.3","Tissue RNA - placenta [nTPM]":"20.8","Tissue RNA - pons [nTPM]":"53.8","Tissue RNA - prostate [nTPM]":"37.9","Tissue RNA - rectum [nTPM]":"17.9","Tissue RNA - retina [nTPM]":"21.8","Tissue RNA - salivary gland [nTPM]":"24.8","Tissue RNA - seminal vesicle [nTPM]":"27.5","Tissue RNA - skeletal muscle [nTPM]":"73.9","Tissue RNA - skin 1 [nTPM]":"23.2","Tissue RNA - small intestine [nTPM]":"19.6","Tissue RNA - smooth muscle [nTPM]":"27.8","Tissue RNA - spinal cord [nTPM]":"51.2","Tissue RNA - spleen [nTPM]":"24.6","Tissue RNA - stomach 1 [nTPM]":"30.3","Tissue RNA - testis [nTPM]":"37.2","Tissue RNA - thalamus [nTPM]":"50.9","Tissue RNA - thymus [nTPM]":"18.8","Tissue RNA - thyroid gland [nTPM]":"37.9","Tissue RNA - tongue [nTPM]":"48.1","Tissue RNA - tonsil [nTPM]":"16.2","Tissue RNA - urinary bladder [nTPM]":"27.8","Tissue RNA - vagina [nTPM]":"21.0","Tissue RNA - white matter [nTPM]":"61.0","Cell RNA - A-431 [nTPM]":"37.7","Cell RNA - A549 [nTPM]":"39.6","Cell RNA - AF22 [nTPM]":"47.3","Cell RNA - AN3-CA [nTPM]":"46.0","Cell RNA - ASC diff [nTPM]":"51.0","Cell RNA - ASC TERT1 [nTPM]":"55.3","Cell RNA - BEWO [nTPM]":"60.9","Cell RNA - BJ [nTPM]":"49.3","Cell RNA - BJ hTERT+ [nTPM]":"82.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.5","Cell RNA - CACO-2 [nTPM]":"22.6","Cell RNA - CAPAN-2 [nTPM]":"30.5","Cell RNA - Daudi [nTPM]":"34.6","Cell RNA - EFO-21 [nTPM]":"79.7","Cell RNA - fHDF\/TERT166 [nTPM]":"82.3","Cell RNA - GAMG [nTPM]":"112.3","Cell RNA - HaCaT [nTPM]":"21.1","Cell RNA - HAP1 [nTPM]":"34.2","Cell RNA - HBEC3-KT [nTPM]":"70.5","Cell RNA - HBF TERT88 [nTPM]":"39.3","Cell RNA - HDLM-2 [nTPM]":"45.4","Cell RNA - HEK 293 [nTPM]":"38.6","Cell RNA - HEL [nTPM]":"27.3","Cell RNA - HeLa [nTPM]":"34.2","Cell RNA - Hep G2 [nTPM]":"34.3","Cell RNA - HHSteC [nTPM]":"44.6","Cell RNA - HL-60 [nTPM]":"21.3","Cell RNA - HMC-1 [nTPM]":"25.8","Cell RNA - HSkMC [nTPM]":"56.2","Cell RNA - hTCEpi [nTPM]":"90.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"73.7","Cell RNA - hTERT-HME1 [nTPM]":"68.2","Cell RNA - hTERT-RPE1 [nTPM]":"118.0","Cell RNA - HUVEC TERT2 [nTPM]":"68.0","Cell RNA - JURKAT [nTPM]":"46.6","Cell RNA - K-562 [nTPM]":"32.9","Cell RNA - Karpas-707 [nTPM]":"21.9","Cell RNA - LHCN-M2 [nTPM]":"108.9","Cell RNA - MCF7 [nTPM]":"26.2","Cell RNA - MOLT-4 [nTPM]":"37.8","Cell RNA - NB-4 [nTPM]":"15.3","Cell RNA - NTERA-2 [nTPM]":"39.2","Cell RNA - OE19 [nTPM]":"21.5","Cell RNA - PC-3 [nTPM]":"54.7","Cell RNA - REH [nTPM]":"27.2","Cell RNA - RH-30 [nTPM]":"48.4","Cell RNA - RPMI-8226 [nTPM]":"32.7","Cell RNA - RPTEC TERT1 [nTPM]":"58.2","Cell RNA - RT4 [nTPM]":"45.9","Cell RNA - SCLC-21H [nTPM]":"17.9","Cell RNA - SH-SY5Y [nTPM]":"64.1","Cell RNA - SiHa [nTPM]":"45.7","Cell RNA - SK-BR-3 [nTPM]":"52.1","Cell RNA - SK-MEL-30 [nTPM]":"70.7","Cell RNA - SuSa [nTPM]":"67.4","Cell RNA - T-47d [nTPM]":"34.8","Cell RNA - THP-1 [nTPM]":"29.8","Cell RNA - TIME [nTPM]":"50.0","Cell RNA - U-138 MG [nTPM]":"49.2","Cell RNA - U-2 OS [nTPM]":"43.5","Cell RNA - U-2197 [nTPM]":"56.4","Cell RNA - U-251 MG [nTPM]":"96.4","Cell RNA - U-266\/70 [nTPM]":"54.7","Cell RNA - U-266\/84 [nTPM]":"65.3","Cell RNA - U-698 [nTPM]":"16.1","Cell RNA - U-87 MG [nTPM]":"75.1","Cell RNA - U-937 [nTPM]":"20.8","Cell RNA - WM-115 [nTPM]":"53.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"6.2","Blood RNA - non-classical monocyte [nTPM]":"4.1","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"45.8","Brain RNA - basal ganglia [nTPM]":"51.9","Brain RNA - cerebellum [nTPM]":"52.7","Brain RNA - cerebral cortex [nTPM]":"50.4","Brain RNA - hippocampal formation [nTPM]":"45.9","Brain RNA - hypothalamus [nTPM]":"49.8","Brain RNA - medulla oblongata [nTPM]":"55.0","Brain RNA - midbrain [nTPM]":"53.3","Brain RNA - pons [nTPM]":"53.8","Brain RNA - spinal cord [nTPM]":"51.2","Brain RNA - thalamus [nTPM]":"50.9","Brain RNA - white matter [nTPM]":"61.0","Single Cell Type RNA - Adipocytes [nTPM]":"12.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.4","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"11.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"38.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"30.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - dendritic cells [nTPM]":"17.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"39.3","Single Cell Type RNA - Early spermatids [nTPM]":"47.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.7","Single Cell Type RNA - Endothelial cells [nTPM]":"17.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"39.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.4","Single Cell Type RNA - Fibroblasts [nTPM]":"14.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.1","Single Cell Type RNA - granulocytes [nTPM]":"27.1","Single Cell Type RNA - Granulosa cells [nTPM]":"25.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"20.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.6","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.6","Single Cell Type RNA - Langerhans cells [nTPM]":"6.4","Single Cell Type RNA - Late spermatids [nTPM]":"15.6","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"10.6","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"18.0","Single Cell Type RNA - Muller glia cells [nTPM]":"21.9","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.7","Single Cell Type RNA - Paneth cells [nTPM]":"14.5","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"16.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.4","Single Cell Type RNA - Spermatocytes [nTPM]":"11.2","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.4","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"19.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.4","Single Cell Type RNA - Urothelial cells [nTPM]":"33.0"},{"Gene":"PON1","Gene synonym":["ESA","PON"],"Ensembl":"ENSG00000005421","Gene description":"Paraoxonase 1","Uniprot":["P27169"],"Chromosome":"7","Position":"95297676-95324532","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"103","RNA tissue specific nTPM":{"liver":"531.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"23","RNA single cell type specific nTPM":{"Hepatocytes":"440.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"78","RNA cancer specific FPKM":{"liver cancer":"97.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001610"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":96000000000,"Blood concentration - Conc. blood MS [pg\/L]":"17000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001610":"AB_1079656"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.24e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"531.8","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"440.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"13.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"POU3F4","Gene synonym":["BRN4","DFN3","DFNX2","OTF9"],"Ensembl":"ENSG00000196767","Gene description":"POU class 3 homeobox 4","Uniprot":[],"Chromosome":"X","Position":"83508290-83512127","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"11.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Collecting duct cells":"11.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"21","RNA cancer specific FPKM":{"glioma":"5.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"99","RNA cell line specific nTPM":{"AF22":"9.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062295"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA062295":"AB_2732681"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"11.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"5.5","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"2.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"3.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"9.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"11.9","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"5.5","Brain RNA - pons [nTPM]":"2.5","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"3.4","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"POU4F3","Gene synonym":["BRN3C","DFNA15","DFNA42","DFNA52"],"Ensembl":"ENSG00000091010","Gene description":"POU class 4 homeobox 3","Uniprot":["Q15319"],"Chromosome":"5","Position":"146338839-146341728","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038215"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA038215":"AB_10697245"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PPIP5K2","Gene synonym":["CFAP160","DFNB100","HISPPD1","KIAA0433","VIP2"],"Ensembl":"ENSG00000145725","Gene description":"Diphosphoinositol pentakisphosphate kinase 2","Uniprot":["O43314"],"Chromosome":"5","Position":"103120149-103212799","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"160.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037895","HPA038442"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA037895":"AB_2675724","HPA038442":"AB_10673173"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.7","Tissue RNA - adrenal gland [nTPM]":"19.1","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"22.0","Tissue RNA - basal ganglia [nTPM]":"7.9","Tissue RNA - bone marrow [nTPM]":"51.6","Tissue RNA - breast [nTPM]":"25.1","Tissue RNA - cerebellum [nTPM]":"18.9","Tissue RNA - cerebral cortex [nTPM]":"13.9","Tissue RNA - cervix [nTPM]":"22.2","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"28.1","Tissue RNA - duodenum [nTPM]":"18.3","Tissue RNA - endometrium 1 [nTPM]":"20.6","Tissue RNA - epididymis [nTPM]":"21.2","Tissue RNA - esophagus [nTPM]":"17.1","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"20.4","Tissue RNA - heart muscle [nTPM]":"19.5","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"8.9","Tissue RNA - kidney [nTPM]":"20.3","Tissue RNA - liver [nTPM]":"29.2","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"25.5","Tissue RNA - medulla oblongata [nTPM]":"15.4","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"26.1","Tissue RNA - pancreas [nTPM]":"26.7","Tissue RNA - parathyroid gland [nTPM]":"23.0","Tissue RNA - pituitary gland [nTPM]":"18.1","Tissue RNA - placenta [nTPM]":"16.7","Tissue RNA - pons [nTPM]":"15.1","Tissue RNA - prostate [nTPM]":"16.3","Tissue RNA - rectum [nTPM]":"25.5","Tissue RNA - retina [nTPM]":"19.2","Tissue RNA - salivary gland [nTPM]":"17.1","Tissue RNA - seminal vesicle [nTPM]":"15.4","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"17.2","Tissue RNA - small intestine [nTPM]":"16.5","Tissue RNA - smooth muscle [nTPM]":"18.4","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"23.9","Tissue RNA - stomach 1 [nTPM]":"22.5","Tissue RNA - testis [nTPM]":"15.1","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"27.9","Tissue RNA - thyroid gland [nTPM]":"23.3","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"24.5","Tissue RNA - urinary bladder [nTPM]":"17.8","Tissue RNA - vagina [nTPM]":"13.9","Tissue RNA - white matter [nTPM]":"10.7","Cell RNA - A-431 [nTPM]":"27.4","Cell RNA - A549 [nTPM]":"25.3","Cell RNA - AF22 [nTPM]":"50.8","Cell RNA - AN3-CA [nTPM]":"65.2","Cell RNA - ASC diff [nTPM]":"40.8","Cell RNA - ASC TERT1 [nTPM]":"53.4","Cell RNA - BEWO [nTPM]":"47.8","Cell RNA - BJ [nTPM]":"63.5","Cell RNA - BJ hTERT+ [nTPM]":"39.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.6","Cell RNA - CACO-2 [nTPM]":"20.9","Cell RNA - CAPAN-2 [nTPM]":"48.3","Cell RNA - Daudi [nTPM]":"67.6","Cell RNA - EFO-21 [nTPM]":"56.2","Cell RNA - fHDF\/TERT166 [nTPM]":"60.9","Cell RNA - GAMG [nTPM]":"52.7","Cell RNA - HaCaT [nTPM]":"16.5","Cell RNA - HAP1 [nTPM]":"43.9","Cell RNA - HBEC3-KT [nTPM]":"33.2","Cell RNA - HBF TERT88 [nTPM]":"57.5","Cell RNA - HDLM-2 [nTPM]":"53.7","Cell RNA - HEK 293 [nTPM]":"23.5","Cell RNA - HEL [nTPM]":"84.7","Cell RNA - HeLa [nTPM]":"44.3","Cell RNA - Hep G2 [nTPM]":"33.4","Cell RNA - HHSteC [nTPM]":"29.0","Cell RNA - HL-60 [nTPM]":"72.1","Cell RNA - HMC-1 [nTPM]":"70.4","Cell RNA - HSkMC [nTPM]":"34.5","Cell RNA - hTCEpi [nTPM]":"23.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"52.0","Cell RNA - hTERT-HME1 [nTPM]":"46.1","Cell RNA - hTERT-RPE1 [nTPM]":"31.2","Cell RNA - HUVEC TERT2 [nTPM]":"40.0","Cell RNA - JURKAT [nTPM]":"42.5","Cell RNA - K-562 [nTPM]":"84.9","Cell RNA - Karpas-707 [nTPM]":"57.0","Cell RNA - LHCN-M2 [nTPM]":"53.1","Cell RNA - MCF7 [nTPM]":"21.3","Cell RNA - MOLT-4 [nTPM]":"60.9","Cell RNA - NB-4 [nTPM]":"44.6","Cell RNA - NTERA-2 [nTPM]":"55.4","Cell RNA - OE19 [nTPM]":"12.7","Cell RNA - PC-3 [nTPM]":"64.4","Cell RNA - REH [nTPM]":"58.6","Cell RNA - RH-30 [nTPM]":"46.7","Cell RNA - RPMI-8226 [nTPM]":"89.3","Cell RNA - RPTEC TERT1 [nTPM]":"36.8","Cell RNA - RT4 [nTPM]":"31.5","Cell RNA - SCLC-21H [nTPM]":"29.6","Cell RNA - SH-SY5Y [nTPM]":"40.1","Cell RNA - SiHa [nTPM]":"43.5","Cell RNA - SK-BR-3 [nTPM]":"39.9","Cell RNA - SK-MEL-30 [nTPM]":"40.7","Cell RNA - SuSa [nTPM]":"34.0","Cell RNA - T-47d [nTPM]":"33.5","Cell RNA - THP-1 [nTPM]":"48.9","Cell RNA - TIME [nTPM]":"42.7","Cell RNA - U-138 MG [nTPM]":"55.8","Cell RNA - U-2 OS [nTPM]":"25.7","Cell RNA - U-2197 [nTPM]":"56.0","Cell RNA - U-251 MG [nTPM]":"45.1","Cell RNA - U-266\/70 [nTPM]":"38.1","Cell RNA - U-266\/84 [nTPM]":"87.3","Cell RNA - U-698 [nTPM]":"91.3","Cell RNA - U-87 MG [nTPM]":"31.5","Cell RNA - U-937 [nTPM]":"116.0","Cell RNA - WM-115 [nTPM]":"51.2","Blood RNA - basophil [nTPM]":"41.7","Blood RNA - classical monocyte [nTPM]":"21.5","Blood RNA - eosinophil [nTPM]":"39.6","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"22.9","Blood RNA - MAIT T-cell [nTPM]":"15.8","Blood RNA - memory B-cell [nTPM]":"19.5","Blood RNA - memory CD4 T-cell [nTPM]":"12.6","Blood RNA - memory CD8 T-cell [nTPM]":"14.2","Blood RNA - myeloid DC [nTPM]":"25.6","Blood RNA - naive B-cell [nTPM]":"16.1","Blood RNA - naive CD4 T-cell [nTPM]":"16.1","Blood RNA - naive CD8 T-cell [nTPM]":"17.0","Blood RNA - neutrophil [nTPM]":"19.7","Blood RNA - NK-cell [nTPM]":"17.8","Blood RNA - non-classical monocyte [nTPM]":"32.4","Blood RNA - plasmacytoid DC [nTPM]":"15.5","Blood RNA - T-reg [nTPM]":"12.3","Blood RNA - total PBMC [nTPM]":"11.1","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"7.9","Brain RNA - cerebellum [nTPM]":"18.9","Brain RNA - cerebral cortex [nTPM]":"13.9","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"8.9","Brain RNA - medulla oblongata [nTPM]":"15.4","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"15.1","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"10.7","Single Cell Type RNA - Adipocytes [nTPM]":"35.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.1","Single Cell Type RNA - Astrocytes [nTPM]":"49.3","Single Cell Type RNA - B-cells [nTPM]":"39.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"38.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"29.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - dendritic cells [nTPM]":"35.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.6","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.7","Single Cell Type RNA - Endothelial cells [nTPM]":"28.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"70.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.2","Single Cell Type RNA - Fibroblasts [nTPM]":"33.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.6","Single Cell Type RNA - granulocytes [nTPM]":"43.6","Single Cell Type RNA - Granulosa cells [nTPM]":"49.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"20.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.6","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"160.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"39.5","Single Cell Type RNA - Langerhans cells [nTPM]":"22.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"29.5","Single Cell Type RNA - Macrophages [nTPM]":"43.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"47.5","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"62.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"67.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"19.1","Single Cell Type RNA - Peritubular cells [nTPM]":"23.7","Single Cell Type RNA - Plasma cells [nTPM]":"56.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.1","Single Cell Type RNA - Spermatocytes [nTPM]":"39.7","Single Cell Type RNA - Spermatogonia [nTPM]":"21.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.0","Single Cell Type RNA - T-cells [nTPM]":"31.6","Single Cell Type RNA - Theca cells [nTPM]":"38.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.1","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"PPP2R2B","Gene synonym":["B55beta","PR52B","PR55-BETA","SCA12"],"Ensembl":"ENSG00000156475","Gene description":"Protein phosphatase 2 regulatory subunit Bbeta","Uniprot":["Q00005"],"Chromosome":"5","Position":"146580742-147084784","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"77.1","retina":"43.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1539.0","Excitatory neurons":"846.0","Inhibitory neurons":"788.8","Late spermatids":"876.4","Oligodendrocyte precursor cells":"1035.4","Oligodendrocytes":"4480.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"7.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"gdT-cell":"5.2","MAIT T-cell":"4.1","memory CD4 T-cell":"2.4","memory CD8 T-cell":"6.2","naive CD8 T-cell":"3.8","NK-cell":"2.9","T-reg":"3.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"NK-cells":"2.9","T-cells":"6.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"7.2","HDLM-2":"24.2","RT4":"12.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038118","HPA042122","HPA042770"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038118":"AB_10697238","HPA042122":"AB_2677859","HPA042770":"AB_2678155"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-4"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"7.8","Tissue RNA - amygdala [nTPM]":"53.9","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"71.4","Tissue RNA - bone marrow [nTPM]":"1.9","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"44.7","Tissue RNA - cerebral cortex [nTPM]":"77.1","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"6.0","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"3.6","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"2.5","Tissue RNA - hippocampal formation [nTPM]":"57.8","Tissue RNA - hypothalamus [nTPM]":"53.9","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"50.7","Tissue RNA - midbrain [nTPM]":"56.3","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"14.8","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"50.4","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"1.9","Tissue RNA - retina [nTPM]":"43.0","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"2.2","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"50.7","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"18.9","Tissue RNA - thalamus [nTPM]":"71.6","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"7.5","Tissue RNA - vagina [nTPM]":"2.0","Tissue RNA - white matter [nTPM]":"73.9","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"2.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"2.3","Cell RNA - CAPAN-2 [nTPM]":"1.9","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"7.2","Cell RNA - HAP1 [nTPM]":"0.5","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"1.8","Cell RNA - HDLM-2 [nTPM]":"24.2","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"1.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.9","Cell RNA - RT4 [nTPM]":"12.5","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"1.9","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"5.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"6.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"3.4","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"53.9","Brain RNA - basal ganglia [nTPM]":"71.4","Brain RNA - cerebellum [nTPM]":"44.7","Brain RNA - cerebral cortex [nTPM]":"77.1","Brain RNA - hippocampal formation [nTPM]":"57.8","Brain RNA - hypothalamus [nTPM]":"53.9","Brain RNA - medulla oblongata [nTPM]":"50.7","Brain RNA - midbrain [nTPM]":"56.3","Brain RNA - pons [nTPM]":"50.4","Brain RNA - spinal cord [nTPM]":"50.7","Brain RNA - thalamus [nTPM]":"71.6","Brain RNA - white matter [nTPM]":"73.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"1539.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"90.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"150.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.9","Single Cell Type RNA - dendritic cells [nTPM]":"30.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"295.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"846.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"788.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.7","Single Cell Type RNA - Late spermatids [nTPM]":"876.4","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"45.0","Single Cell Type RNA - NK-cells [nTPM]":"57.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1035.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4480.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"3.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"275.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - T-cells [nTPM]":"31.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"PPP3CA","Gene synonym":["CALN","CALNA","CNA1","PPP2B"],"Ensembl":"ENSG00000138814","Gene description":"Protein phosphatase 3 catalytic subunit alpha","Uniprot":["Q08209"],"Chromosome":"4","Position":"101023409-101348278","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Hydrolase","Protein phosphatase"],"Disease involvement":["Craniosynostosis","Disease variant","Dwarfism","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"144.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"933.8","Inhibitory neurons":"403.0","Oligodendrocyte precursor cells":"348.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"prostate cancer":"98.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012778","CAB018581"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"94000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB018581":"AB_2168324","HPA012778":"AB_1855660"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.82e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.7","Tissue RNA - adrenal gland [nTPM]":"17.5","Tissue RNA - amygdala [nTPM]":"48.5","Tissue RNA - appendix [nTPM]":"15.7","Tissue RNA - basal ganglia [nTPM]":"144.1","Tissue RNA - bone marrow [nTPM]":"17.2","Tissue RNA - breast [nTPM]":"20.5","Tissue RNA - cerebellum [nTPM]":"63.2","Tissue RNA - cerebral cortex [nTPM]":"125.6","Tissue RNA - cervix [nTPM]":"17.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"19.5","Tissue RNA - duodenum [nTPM]":"11.6","Tissue RNA - endometrium 1 [nTPM]":"11.8","Tissue RNA - epididymis [nTPM]":"13.1","Tissue RNA - esophagus [nTPM]":"14.4","Tissue RNA - fallopian tube [nTPM]":"13.8","Tissue RNA - gallbladder [nTPM]":"13.3","Tissue RNA - heart muscle [nTPM]":"9.2","Tissue RNA - hippocampal formation [nTPM]":"97.4","Tissue RNA - hypothalamus [nTPM]":"25.0","Tissue RNA - kidney [nTPM]":"11.2","Tissue RNA - liver [nTPM]":"17.0","Tissue RNA - lung [nTPM]":"19.9","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"11.0","Tissue RNA - ovary [nTPM]":"17.9","Tissue RNA - pancreas [nTPM]":"9.4","Tissue RNA - parathyroid gland [nTPM]":"8.9","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"13.0","Tissue RNA - pons [nTPM]":"15.7","Tissue RNA - prostate [nTPM]":"66.0","Tissue RNA - rectum [nTPM]":"16.1","Tissue RNA - retina [nTPM]":"27.6","Tissue RNA - salivary gland [nTPM]":"22.2","Tissue RNA - seminal vesicle [nTPM]":"38.4","Tissue RNA - skeletal muscle [nTPM]":"51.2","Tissue RNA - skin 1 [nTPM]":"22.9","Tissue RNA - small intestine [nTPM]":"12.9","Tissue RNA - smooth muscle [nTPM]":"15.5","Tissue RNA - spinal cord [nTPM]":"24.7","Tissue RNA - spleen [nTPM]":"14.5","Tissue RNA - stomach 1 [nTPM]":"22.4","Tissue RNA - testis [nTPM]":"10.6","Tissue RNA - thalamus [nTPM]":"23.9","Tissue RNA - thymus [nTPM]":"12.8","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"29.0","Tissue RNA - tonsil [nTPM]":"18.3","Tissue RNA - urinary bladder [nTPM]":"20.7","Tissue RNA - vagina [nTPM]":"16.0","Tissue RNA - white matter [nTPM]":"54.3","Cell RNA - A-431 [nTPM]":"48.3","Cell RNA - A549 [nTPM]":"33.8","Cell RNA - AF22 [nTPM]":"9.3","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"50.4","Cell RNA - ASC TERT1 [nTPM]":"37.9","Cell RNA - BEWO [nTPM]":"15.8","Cell RNA - BJ [nTPM]":"51.9","Cell RNA - BJ hTERT+ [nTPM]":"47.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.6","Cell RNA - CACO-2 [nTPM]":"18.3","Cell RNA - CAPAN-2 [nTPM]":"59.0","Cell RNA - Daudi [nTPM]":"22.4","Cell RNA - EFO-21 [nTPM]":"20.9","Cell RNA - fHDF\/TERT166 [nTPM]":"47.6","Cell RNA - GAMG [nTPM]":"25.6","Cell RNA - HaCaT [nTPM]":"23.5","Cell RNA - HAP1 [nTPM]":"33.3","Cell RNA - HBEC3-KT [nTPM]":"69.6","Cell RNA - HBF TERT88 [nTPM]":"34.9","Cell RNA - HDLM-2 [nTPM]":"56.0","Cell RNA - HEK 293 [nTPM]":"15.1","Cell RNA - HEL [nTPM]":"35.4","Cell RNA - HeLa [nTPM]":"45.8","Cell RNA - Hep G2 [nTPM]":"25.2","Cell RNA - HHSteC [nTPM]":"36.8","Cell RNA - HL-60 [nTPM]":"59.0","Cell RNA - HMC-1 [nTPM]":"17.8","Cell RNA - HSkMC [nTPM]":"39.6","Cell RNA - hTCEpi [nTPM]":"35.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.3","Cell RNA - hTERT-HME1 [nTPM]":"51.4","Cell RNA - hTERT-RPE1 [nTPM]":"39.1","Cell RNA - HUVEC TERT2 [nTPM]":"38.8","Cell RNA - JURKAT [nTPM]":"14.5","Cell RNA - K-562 [nTPM]":"14.4","Cell RNA - Karpas-707 [nTPM]":"61.1","Cell RNA - LHCN-M2 [nTPM]":"33.5","Cell RNA - MCF7 [nTPM]":"58.0","Cell RNA - MOLT-4 [nTPM]":"12.2","Cell RNA - NB-4 [nTPM]":"44.2","Cell RNA - NTERA-2 [nTPM]":"15.4","Cell RNA - OE19 [nTPM]":"55.7","Cell RNA - PC-3 [nTPM]":"20.7","Cell RNA - REH [nTPM]":"22.1","Cell RNA - RH-30 [nTPM]":"83.2","Cell RNA - RPMI-8226 [nTPM]":"26.5","Cell RNA - RPTEC TERT1 [nTPM]":"20.0","Cell RNA - RT4 [nTPM]":"38.3","Cell RNA - SCLC-21H [nTPM]":"71.5","Cell RNA - SH-SY5Y [nTPM]":"26.2","Cell RNA - SiHa [nTPM]":"43.1","Cell RNA - SK-BR-3 [nTPM]":"35.4","Cell RNA - SK-MEL-30 [nTPM]":"24.6","Cell RNA - SuSa [nTPM]":"12.5","Cell RNA - T-47d [nTPM]":"32.3","Cell RNA - THP-1 [nTPM]":"33.4","Cell RNA - TIME [nTPM]":"42.1","Cell RNA - U-138 MG [nTPM]":"48.7","Cell RNA - U-2 OS [nTPM]":"54.8","Cell RNA - U-2197 [nTPM]":"44.7","Cell RNA - U-251 MG [nTPM]":"34.7","Cell RNA - U-266\/70 [nTPM]":"28.5","Cell RNA - U-266\/84 [nTPM]":"31.5","Cell RNA - U-698 [nTPM]":"40.1","Cell RNA - U-87 MG [nTPM]":"26.6","Cell RNA - U-937 [nTPM]":"31.5","Cell RNA - WM-115 [nTPM]":"13.1","Blood RNA - basophil [nTPM]":"82.5","Blood RNA - classical monocyte [nTPM]":"31.0","Blood RNA - eosinophil [nTPM]":"73.5","Blood RNA - gdT-cell [nTPM]":"35.7","Blood RNA - intermediate monocyte [nTPM]":"33.1","Blood RNA - MAIT T-cell [nTPM]":"41.6","Blood RNA - memory B-cell [nTPM]":"74.1","Blood RNA - memory CD4 T-cell [nTPM]":"33.2","Blood RNA - memory CD8 T-cell [nTPM]":"34.8","Blood RNA - myeloid DC [nTPM]":"28.2","Blood RNA - naive B-cell [nTPM]":"62.8","Blood RNA - naive CD4 T-cell [nTPM]":"15.5","Blood RNA - naive CD8 T-cell [nTPM]":"31.0","Blood RNA - neutrophil [nTPM]":"123.7","Blood RNA - NK-cell [nTPM]":"65.1","Blood RNA - non-classical monocyte [nTPM]":"45.1","Blood RNA - plasmacytoid DC [nTPM]":"51.9","Blood RNA - T-reg [nTPM]":"25.3","Blood RNA - total PBMC [nTPM]":"21.1","Brain RNA - amygdala [nTPM]":"48.5","Brain RNA - basal ganglia [nTPM]":"144.1","Brain RNA - cerebellum [nTPM]":"63.2","Brain RNA - cerebral cortex [nTPM]":"125.6","Brain RNA - hippocampal formation [nTPM]":"97.4","Brain RNA - hypothalamus [nTPM]":"25.0","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"11.0","Brain RNA - pons [nTPM]":"15.7","Brain RNA - spinal cord [nTPM]":"24.7","Brain RNA - thalamus [nTPM]":"23.9","Brain RNA - white matter [nTPM]":"54.3","Single Cell Type RNA - Adipocytes [nTPM]":"143.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.6","Single Cell Type RNA - Astrocytes [nTPM]":"284.1","Single Cell Type RNA - B-cells [nTPM]":"96.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"168.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Bipolar cells [nTPM]":"89.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"93.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"51.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"21.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.6","Single Cell Type RNA - dendritic cells [nTPM]":"81.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"60.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"21.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.2","Single Cell Type RNA - Endothelial cells [nTPM]":"100.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"127.4","Single Cell Type RNA - Erythroid cells [nTPM]":"32.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"933.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"84.0","Single Cell Type RNA - Fibroblasts [nTPM]":"75.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"59.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.8","Single Cell Type RNA - granulocytes [nTPM]":"35.4","Single Cell Type RNA - Granulosa cells [nTPM]":"22.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.2","Single Cell Type RNA - Hepatocytes [nTPM]":"39.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.3","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"403.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"61.8","Single Cell Type RNA - Langerhans cells [nTPM]":"135.3","Single Cell Type RNA - Late spermatids [nTPM]":"8.4","Single Cell Type RNA - Leydig cells [nTPM]":"65.0","Single Cell Type RNA - Macrophages [nTPM]":"58.2","Single Cell Type RNA - Melanocytes [nTPM]":"92.5","Single Cell Type RNA - Microglial cells [nTPM]":"281.1","Single Cell Type RNA - monocytes [nTPM]":"64.3","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"348.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"139.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"53.3","Single Cell Type RNA - Paneth cells [nTPM]":"115.4","Single Cell Type RNA - Peritubular cells [nTPM]":"60.9","Single Cell Type RNA - Plasma cells [nTPM]":"63.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"127.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"51.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"82.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"66.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"67.5","Single Cell Type RNA - Spermatocytes [nTPM]":"12.7","Single Cell Type RNA - Spermatogonia [nTPM]":"26.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"172.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.5","Single Cell Type RNA - T-cells [nTPM]":"69.1","Single Cell Type RNA - Theca cells [nTPM]":"76.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.9","Single Cell Type RNA - Urothelial cells [nTPM]":"39.5"},{"Gene":"PRCD","Gene synonym":["RP36"],"Ensembl":"ENSG00000214140","Gene description":"Photoreceptor disc component","Uniprot":["Q00LT1"],"Chromosome":"17","Position":"76527586-76553578","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"retina":"48.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"134.3","Cone photoreceptor cells":"152.2","Muller glia cells":"100.4","Rod photoreceptor cells":"551.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"1.6","Hep G2":"2.1","HSkMC":"1.1","SH-SY5Y":"2.4"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"1.5","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"48.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"2.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"13.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"134.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"152.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"7.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"11.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"100.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"551.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PRDM12","Gene synonym":["PFM9"],"Ensembl":"ENSG00000130711","Gene description":"PR\/SET domain 12","Uniprot":["Q9H4Q4"],"Chromosome":"9","Position":"130664594-130682986","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"2.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1.6","Excitatory neurons":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"2.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"23","RNA cell line specific nTPM":{"RH-30":"19.1"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"basal ganglia":"10.9"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"26","RNA pig brain regional specific nTPM":{"basal ganglia":"3.8","hypothalamus":"1.3"},"Antibody":["HPA043143"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA043143":"AB_10806379"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"19.1","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PRDM8","Gene synonym":["KMT8D"],"Ensembl":"ENSG00000152784","Gene description":"PR\/SET domain 8","Uniprot":["Q9NQV8"],"Chromosome":"4","Position":"80183879-80204329","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"26.1","seminal vesicle":"27.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Bipolar cells":"271.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"4.6"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"17.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-RPE1":"27.3","LHCN-M2":"41.7","NB-4":"48.2","SCLC-21H":"99.3"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hippocampal formation":"28.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057253"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA057253":"AB_2683382"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"10.2","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"17.0","Tissue RNA - cervix [nTPM]":"11.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"1.7","Tissue RNA - hippocampal formation [nTPM]":"13.7","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"5.2","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"26.1","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"24.1","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"27.2","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"3.8","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"10.2","Tissue RNA - vagina [nTPM]":"9.8","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.1","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"20.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"2.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"7.2","Cell RNA - GAMG [nTPM]":"1.8","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"2.4","Cell RNA - HBF TERT88 [nTPM]":"12.1","Cell RNA - HDLM-2 [nTPM]":"8.8","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"4.1","Cell RNA - HL-60 [nTPM]":"9.1","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"4.4","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.1","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"27.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"2.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"3.7","Cell RNA - LHCN-M2 [nTPM]":"41.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"4.2","Cell RNA - NB-4 [nTPM]":"48.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"17.0","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"1.2","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"99.3","Cell RNA - SH-SY5Y [nTPM]":"13.8","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"4.5","Cell RNA - TIME [nTPM]":"8.8","Cell RNA - U-138 MG [nTPM]":"7.1","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"5.2","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"1.7","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"17.8","Cell RNA - U-937 [nTPM]":"4.2","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"10.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"17.0","Brain RNA - hippocampal formation [nTPM]":"13.7","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"271.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"8.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.2","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"5.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"PREPL","Gene synonym":["KIAA0436"],"Ensembl":"ENSG00000138078","Gene description":"Prolyl endopeptidase like","Uniprot":["Q4J6C6"],"Chromosome":"2","Position":"44316281-44361862","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"243.1","Inhibitory neurons":"219.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063238"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063238":"AB_2684967"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.2","Tissue RNA - adrenal gland [nTPM]":"50.9","Tissue RNA - amygdala [nTPM]":"64.6","Tissue RNA - appendix [nTPM]":"18.4","Tissue RNA - basal ganglia [nTPM]":"67.4","Tissue RNA - bone marrow [nTPM]":"5.5","Tissue RNA - breast [nTPM]":"31.9","Tissue RNA - cerebellum [nTPM]":"42.9","Tissue RNA - cerebral cortex [nTPM]":"133.1","Tissue RNA - cervix [nTPM]":"35.9","Tissue RNA - choroid plexus [nTPM]":"27.5","Tissue RNA - colon [nTPM]":"24.4","Tissue RNA - duodenum [nTPM]":"26.1","Tissue RNA - endometrium 1 [nTPM]":"47.2","Tissue RNA - epididymis [nTPM]":"70.9","Tissue RNA - esophagus [nTPM]":"22.9","Tissue RNA - fallopian tube [nTPM]":"33.6","Tissue RNA - gallbladder [nTPM]":"28.4","Tissue RNA - heart muscle [nTPM]":"62.7","Tissue RNA - hippocampal formation [nTPM]":"73.1","Tissue RNA - hypothalamus [nTPM]":"93.1","Tissue RNA - kidney [nTPM]":"62.5","Tissue RNA - liver [nTPM]":"21.6","Tissue RNA - lung [nTPM]":"24.5","Tissue RNA - lymph node [nTPM]":"17.4","Tissue RNA - medulla oblongata [nTPM]":"45.3","Tissue RNA - midbrain [nTPM]":"26.0","Tissue RNA - ovary [nTPM]":"49.8","Tissue RNA - pancreas [nTPM]":"25.2","Tissue RNA - parathyroid gland [nTPM]":"54.4","Tissue RNA - pituitary gland [nTPM]":"52.5","Tissue RNA - placenta [nTPM]":"21.4","Tissue RNA - pons [nTPM]":"41.7","Tissue RNA - prostate [nTPM]":"37.3","Tissue RNA - rectum [nTPM]":"29.4","Tissue RNA - retina [nTPM]":"123.8","Tissue RNA - salivary gland [nTPM]":"26.2","Tissue RNA - seminal vesicle [nTPM]":"33.1","Tissue RNA - skeletal muscle [nTPM]":"34.3","Tissue RNA - skin 1 [nTPM]":"22.3","Tissue RNA - small intestine [nTPM]":"27.9","Tissue RNA - smooth muscle [nTPM]":"34.1","Tissue RNA - spinal cord [nTPM]":"34.0","Tissue RNA - spleen [nTPM]":"23.1","Tissue RNA - stomach 1 [nTPM]":"26.4","Tissue RNA - testis [nTPM]":"28.2","Tissue RNA - thalamus [nTPM]":"53.4","Tissue RNA - thymus [nTPM]":"19.1","Tissue RNA - thyroid gland [nTPM]":"61.3","Tissue RNA - tongue [nTPM]":"51.3","Tissue RNA - tonsil [nTPM]":"17.9","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"23.9","Tissue RNA - white matter [nTPM]":"58.4","Cell RNA - A-431 [nTPM]":"41.2","Cell RNA - A549 [nTPM]":"31.7","Cell RNA - AF22 [nTPM]":"35.3","Cell RNA - AN3-CA [nTPM]":"45.3","Cell RNA - ASC diff [nTPM]":"55.7","Cell RNA - ASC TERT1 [nTPM]":"58.0","Cell RNA - BEWO [nTPM]":"26.8","Cell RNA - BJ [nTPM]":"45.1","Cell RNA - BJ hTERT+ [nTPM]":"34.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.4","Cell RNA - CACO-2 [nTPM]":"34.1","Cell RNA - CAPAN-2 [nTPM]":"28.4","Cell RNA - Daudi [nTPM]":"52.3","Cell RNA - EFO-21 [nTPM]":"61.2","Cell RNA - fHDF\/TERT166 [nTPM]":"47.5","Cell RNA - GAMG [nTPM]":"36.6","Cell RNA - HaCaT [nTPM]":"34.6","Cell RNA - HAP1 [nTPM]":"50.6","Cell RNA - HBEC3-KT [nTPM]":"33.0","Cell RNA - HBF TERT88 [nTPM]":"61.0","Cell RNA - HDLM-2 [nTPM]":"48.7","Cell RNA - HEK 293 [nTPM]":"36.2","Cell RNA - HEL [nTPM]":"35.5","Cell RNA - HeLa [nTPM]":"24.2","Cell RNA - Hep G2 [nTPM]":"26.3","Cell RNA - HHSteC [nTPM]":"40.0","Cell RNA - HL-60 [nTPM]":"35.8","Cell RNA - HMC-1 [nTPM]":"32.5","Cell RNA - HSkMC [nTPM]":"37.9","Cell RNA - hTCEpi [nTPM]":"64.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"61.8","Cell RNA - hTERT-HME1 [nTPM]":"50.1","Cell RNA - hTERT-RPE1 [nTPM]":"62.9","Cell RNA - HUVEC TERT2 [nTPM]":"31.4","Cell RNA - JURKAT [nTPM]":"24.3","Cell RNA - K-562 [nTPM]":"45.6","Cell RNA - Karpas-707 [nTPM]":"72.6","Cell RNA - LHCN-M2 [nTPM]":"43.6","Cell RNA - MCF7 [nTPM]":"22.2","Cell RNA - MOLT-4 [nTPM]":"39.1","Cell RNA - NB-4 [nTPM]":"17.4","Cell RNA - NTERA-2 [nTPM]":"33.4","Cell RNA - OE19 [nTPM]":"52.8","Cell RNA - PC-3 [nTPM]":"35.1","Cell RNA - REH [nTPM]":"30.1","Cell RNA - RH-30 [nTPM]":"42.8","Cell RNA - RPMI-8226 [nTPM]":"38.0","Cell RNA - RPTEC TERT1 [nTPM]":"61.4","Cell RNA - RT4 [nTPM]":"24.0","Cell RNA - SCLC-21H [nTPM]":"58.3","Cell RNA - SH-SY5Y [nTPM]":"46.5","Cell RNA - SiHa [nTPM]":"28.9","Cell RNA - SK-BR-3 [nTPM]":"30.6","Cell RNA - SK-MEL-30 [nTPM]":"67.4","Cell RNA - SuSa [nTPM]":"33.9","Cell RNA - T-47d [nTPM]":"41.4","Cell RNA - THP-1 [nTPM]":"27.6","Cell RNA - TIME [nTPM]":"32.8","Cell RNA - U-138 MG [nTPM]":"56.3","Cell RNA - U-2 OS [nTPM]":"32.1","Cell RNA - U-2197 [nTPM]":"44.6","Cell RNA - U-251 MG [nTPM]":"31.0","Cell RNA - U-266\/70 [nTPM]":"40.2","Cell RNA - U-266\/84 [nTPM]":"28.2","Cell RNA - U-698 [nTPM]":"34.3","Cell RNA - U-87 MG [nTPM]":"65.9","Cell RNA - U-937 [nTPM]":"40.1","Cell RNA - WM-115 [nTPM]":"42.5","Blood RNA - basophil [nTPM]":"6.9","Blood RNA - classical monocyte [nTPM]":"4.4","Blood RNA - eosinophil [nTPM]":"3.5","Blood RNA - gdT-cell [nTPM]":"7.9","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"11.2","Blood RNA - memory B-cell [nTPM]":"8.5","Blood RNA - memory CD4 T-cell [nTPM]":"7.3","Blood RNA - memory CD8 T-cell [nTPM]":"8.5","Blood RNA - myeloid DC [nTPM]":"6.3","Blood RNA - naive B-cell [nTPM]":"7.0","Blood RNA - naive CD4 T-cell [nTPM]":"10.7","Blood RNA - naive CD8 T-cell [nTPM]":"8.7","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"11.1","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"8.8","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"64.6","Brain RNA - basal ganglia [nTPM]":"67.4","Brain RNA - cerebellum [nTPM]":"42.9","Brain RNA - cerebral cortex [nTPM]":"133.1","Brain RNA - hippocampal formation [nTPM]":"73.1","Brain RNA - hypothalamus [nTPM]":"93.1","Brain RNA - medulla oblongata [nTPM]":"45.3","Brain RNA - midbrain [nTPM]":"26.0","Brain RNA - pons [nTPM]":"41.7","Brain RNA - spinal cord [nTPM]":"34.0","Brain RNA - thalamus [nTPM]":"53.4","Brain RNA - white matter [nTPM]":"58.4","Single Cell Type RNA - Adipocytes [nTPM]":"16.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.4","Single Cell Type RNA - Astrocytes [nTPM]":"83.2","Single Cell Type RNA - B-cells [nTPM]":"34.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"89.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"88.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"21.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"64.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.7","Single Cell Type RNA - dendritic cells [nTPM]":"30.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"17.4","Single Cell Type RNA - Early spermatids [nTPM]":"21.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.7","Single Cell Type RNA - Endothelial cells [nTPM]":"18.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"243.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.9","Single Cell Type RNA - Fibroblasts [nTPM]":"29.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.1","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"21.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"32.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.6","Single Cell Type RNA - Horizontal cells [nTPM]":"144.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"219.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"13.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"10.0","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"55.3","Single Cell Type RNA - monocytes [nTPM]":"12.8","Single Cell Type RNA - Muller glia cells [nTPM]":"41.4","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"81.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"126.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.6","Single Cell Type RNA - Paneth cells [nTPM]":"20.8","Single Cell Type RNA - Peritubular cells [nTPM]":"33.1","Single Cell Type RNA - Plasma cells [nTPM]":"21.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"63.2","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.2","Single Cell Type RNA - Spermatocytes [nTPM]":"29.2","Single Cell Type RNA - Spermatogonia [nTPM]":"28.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"29.1","Single Cell Type RNA - Theca cells [nTPM]":"26.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"PRICKLE1","Gene synonym":["EPM1B","FLJ31937","RILP"],"Ensembl":"ENSG00000139174","Gene description":"Prickle planar cell polarity protein 1","Uniprot":["Q96MT3"],"Chromosome":"12","Position":"42456757-42590355","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"72.8","Excitatory neurons":"307.7","Inhibitory neurons":"122.2","Microglial cells":"64.6","Oligodendrocyte precursor cells":"114.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"7.6","naive B-cell":"11.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"11.5"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"HBEC3-KT":"1015.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001379","HPA050037"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA001379":"AB_1855703","HPA050037":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.93e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-4"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"5.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"7.2","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"10.0","Tissue RNA - heart muscle [nTPM]":"13.8","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"5.0","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"9.5","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"12.5","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"2.0","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"5.6","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"12.7","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"14.8","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"6.0","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"7.7","Cell RNA - A549 [nTPM]":"4.4","Cell RNA - AF22 [nTPM]":"17.0","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"12.4","Cell RNA - ASC TERT1 [nTPM]":"13.1","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"11.0","Cell RNA - BJ hTERT+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.1","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"16.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"31.4","Cell RNA - fHDF\/TERT166 [nTPM]":"1.6","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"12.5","Cell RNA - HBEC3-KT [nTPM]":"1015.4","Cell RNA - HBF TERT88 [nTPM]":"3.5","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"6.4","Cell RNA - HEL [nTPM]":"17.5","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"19.3","Cell RNA - hTCEpi [nTPM]":"7.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.7","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"39.7","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"3.1","Cell RNA - LHCN-M2 [nTPM]":"2.9","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"56.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"18.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"21.1","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"4.4","Cell RNA - SH-SY5Y [nTPM]":"3.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"13.7","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"35.1","Cell RNA - TIME [nTPM]":"2.9","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"13.4","Cell RNA - U-2197 [nTPM]":"14.0","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"6.1","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"10.7","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"7.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"11.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"7.2","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"13.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"13.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"2.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.8","Single Cell Type RNA - Early spermatids [nTPM]":"72.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"307.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"19.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"59.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"122.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"25.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"64.6","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"2.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"114.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"24.8","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.9","Single Cell Type RNA - Spermatocytes [nTPM]":"5.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"18.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"PRICKLE2","Gene synonym":["DKFZp686D143"],"Ensembl":"ENSG00000163637","Gene description":"Prickle planar cell polarity protein 2","Uniprot":["Q7Z3G6"],"Chromosome":"3","Position":"64092236-64445476","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"114.3","Excitatory neurons":"185.5","Inhibitory neurons":"232.4","Microglial cells":"112.4","Oligodendrocyte precursor cells":"103.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"24.1","ASC TERT1":"14.9","HSkMC":"22.1","U-87 MG":"15.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035493"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA035493":"AB_10696504"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Tissue RNA - adipose tissue [nTPM]":"20.8","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"14.1","Tissue RNA - appendix [nTPM]":"3.9","Tissue RNA - basal ganglia [nTPM]":"14.9","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"8.0","Tissue RNA - cerebellum [nTPM]":"3.4","Tissue RNA - cerebral cortex [nTPM]":"15.8","Tissue RNA - cervix [nTPM]":"16.4","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"18.4","Tissue RNA - duodenum [nTPM]":"2.3","Tissue RNA - endometrium 1 [nTPM]":"17.3","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"5.6","Tissue RNA - hippocampal formation [nTPM]":"28.5","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"3.1","Tissue RNA - lung [nTPM]":"10.6","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"8.9","Tissue RNA - ovary [nTPM]":"8.4","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"5.4","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"5.6","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"13.8","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"5.9","Tissue RNA - smooth muscle [nTPM]":"16.6","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"11.7","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"8.8","Tissue RNA - white matter [nTPM]":"9.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"4.7","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"24.1","Cell RNA - ASC TERT1 [nTPM]":"14.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"3.5","Cell RNA - BJ hTERT+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.2","Cell RNA - CACO-2 [nTPM]":"8.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.4","Cell RNA - GAMG [nTPM]":"7.6","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"3.2","Cell RNA - HBF TERT88 [nTPM]":"2.8","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"6.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"22.1","Cell RNA - hTCEpi [nTPM]":"4.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.2","Cell RNA - hTERT-HME1 [nTPM]":"3.5","Cell RNA - hTERT-RPE1 [nTPM]":"8.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"3.9","Cell RNA - MCF7 [nTPM]":"4.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"4.5","Cell RNA - RT4 [nTPM]":"11.7","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"7.7","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"11.9","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"2.9","Cell RNA - U-251 MG [nTPM]":"6.9","Cell RNA - U-266\/70 [nTPM]":"3.7","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"15.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"14.1","Brain RNA - basal ganglia [nTPM]":"14.9","Brain RNA - cerebellum [nTPM]":"3.4","Brain RNA - cerebral cortex [nTPM]":"15.8","Brain RNA - hippocampal formation [nTPM]":"28.5","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"8.9","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"11.7","Brain RNA - white matter [nTPM]":"9.3","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.9","Single Cell Type RNA - Astrocytes [nTPM]":"114.3","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"25.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.7","Single Cell Type RNA - Early spermatids [nTPM]":"15.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"47.5","Single Cell Type RNA - Endothelial cells [nTPM]":"9.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"185.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"20.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"232.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"112.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"103.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"6.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"2.7"},{"Gene":"PRIMPOL","Gene synonym":["CCDC111","FLJ33167"],"Ensembl":"ENSG00000164306","Gene description":"Primase and DNA directed polymerase","Uniprot":["Q96LW4"],"Chromosome":"4","Position":"184649667-184694963","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Transcription"],"Molecular function":["DNA-directed DNA polymerase","Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Intestinal goblet cells":"58.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"24.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"24.0"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054372"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA054372":"AB_2682466"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.2","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"4.9","Tissue RNA - bone marrow [nTPM]":"5.5","Tissue RNA - breast [nTPM]":"8.9","Tissue RNA - cerebellum [nTPM]":"7.6","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"8.5","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"7.9","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"8.2","Tissue RNA - esophagus [nTPM]":"7.0","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"6.9","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"6.8","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"7.9","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"6.8","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"4.3","Tissue RNA - prostate [nTPM]":"7.1","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"8.2","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"6.6","Tissue RNA - small intestine [nTPM]":"6.7","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"8.6","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"5.3","Tissue RNA - tonsil [nTPM]":"6.4","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"5.6","Cell RNA - A-431 [nTPM]":"13.1","Cell RNA - A549 [nTPM]":"5.7","Cell RNA - AF22 [nTPM]":"13.2","Cell RNA - AN3-CA [nTPM]":"15.0","Cell RNA - ASC diff [nTPM]":"17.5","Cell RNA - ASC TERT1 [nTPM]":"23.2","Cell RNA - BEWO [nTPM]":"8.9","Cell RNA - BJ [nTPM]":"13.8","Cell RNA - BJ hTERT+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.9","Cell RNA - CACO-2 [nTPM]":"4.4","Cell RNA - CAPAN-2 [nTPM]":"13.3","Cell RNA - Daudi [nTPM]":"7.5","Cell RNA - EFO-21 [nTPM]":"5.0","Cell RNA - fHDF\/TERT166 [nTPM]":"10.6","Cell RNA - GAMG [nTPM]":"12.6","Cell RNA - HaCaT [nTPM]":"7.9","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"14.6","Cell RNA - HBF TERT88 [nTPM]":"24.0","Cell RNA - HDLM-2 [nTPM]":"15.9","Cell RNA - HEK 293 [nTPM]":"5.3","Cell RNA - HEL [nTPM]":"7.8","Cell RNA - HeLa [nTPM]":"7.8","Cell RNA - Hep G2 [nTPM]":"5.3","Cell RNA - HHSteC [nTPM]":"11.4","Cell RNA - HL-60 [nTPM]":"6.4","Cell RNA - HMC-1 [nTPM]":"11.5","Cell RNA - HSkMC [nTPM]":"14.5","Cell RNA - hTCEpi [nTPM]":"11.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.2","Cell RNA - hTERT-HME1 [nTPM]":"13.7","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"12.6","Cell RNA - JURKAT [nTPM]":"20.7","Cell RNA - K-562 [nTPM]":"16.5","Cell RNA - Karpas-707 [nTPM]":"24.0","Cell RNA - LHCN-M2 [nTPM]":"16.5","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"13.3","Cell RNA - NB-4 [nTPM]":"5.4","Cell RNA - NTERA-2 [nTPM]":"4.3","Cell RNA - OE19 [nTPM]":"5.8","Cell RNA - PC-3 [nTPM]":"4.6","Cell RNA - REH [nTPM]":"12.3","Cell RNA - RH-30 [nTPM]":"9.4","Cell RNA - RPMI-8226 [nTPM]":"9.0","Cell RNA - RPTEC TERT1 [nTPM]":"11.8","Cell RNA - RT4 [nTPM]":"7.8","Cell RNA - SCLC-21H [nTPM]":"9.4","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"8.3","Cell RNA - SK-BR-3 [nTPM]":"2.1","Cell RNA - SK-MEL-30 [nTPM]":"15.2","Cell RNA - SuSa [nTPM]":"10.4","Cell RNA - T-47d [nTPM]":"6.6","Cell RNA - THP-1 [nTPM]":"12.3","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"7.5","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"5.9","Cell RNA - U-251 MG [nTPM]":"8.9","Cell RNA - U-266\/70 [nTPM]":"13.4","Cell RNA - U-266\/84 [nTPM]":"10.2","Cell RNA - U-698 [nTPM]":"3.8","Cell RNA - U-87 MG [nTPM]":"11.1","Cell RNA - U-937 [nTPM]":"8.5","Cell RNA - WM-115 [nTPM]":"18.6","Blood RNA - basophil [nTPM]":"11.2","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"24.0","Blood RNA - gdT-cell [nTPM]":"3.8","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"3.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"3.2","Blood RNA - naive B-cell [nTPM]":"3.7","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"5.6","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"4.6","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"4.9","Brain RNA - cerebellum [nTPM]":"7.6","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"4.3","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"5.6","Single Cell Type RNA - Adipocytes [nTPM]":"7.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"6.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.3","Single Cell Type RNA - dendritic cells [nTPM]":"8.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.7","Single Cell Type RNA - Early spermatids [nTPM]":"5.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"17.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.3","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"12.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"58.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"14.8","Single Cell Type RNA - Langerhans cells [nTPM]":"6.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.7","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"9.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"6.5","Single Cell Type RNA - Muller glia cells [nTPM]":"11.1","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"10.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"8.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"18.8","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"8.9","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.0","Single Cell Type RNA - Urothelial cells [nTPM]":"5.4"},{"Gene":"PRKCG","Gene synonym":["MGC57564","PKC\u00c3\u017d\u00c2\u00b3","PKCC","PKCG","SCA14"],"Ensembl":"ENSG00000126583","Gene description":"Protein kinase C gamma","Uniprot":["P05129"],"Chromosome":"19","Position":"53879190-53907652","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Biological rhythms"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"20","RNA tissue specific nTPM":{"brain":"103.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"22.6","Glandular and luminal cells":"5.1","Horizontal cells":"5.0","Inhibitory neurons":"12.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"103.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"2.2","OE19":"4.0","SH-SY5Y":"1.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054560"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054560":"AB_2682523"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"47.5","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"44.8","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"64.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"103.3","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"18.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"2.2","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"4.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"47.5","Brain RNA - basal ganglia [nTPM]":"44.8","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"64.8","Brain RNA - hippocampal formation [nTPM]":"103.3","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"18.3","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PRKN","Gene synonym":["AR-JP","PARK2","parkin","PDJ"],"Ensembl":"ENSG00000185345","Gene description":"Parkin RBR E3 ubiquitin protein ligase","Uniprot":["O60260"],"Chromosome":"6","Position":"161347417-162727775","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"28.3","tongue":"15.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"9.6","Alveolar cells type 2":"4.8","Distal tubular cells":"19.6","Proximal tubular cells":"6.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"3.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"2.0","HEL":"4.1","HSkMC":"1.7","Karpas-707":"2.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016257","HPA036012"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016257":"AB_628104","HPA036012":"AB_2732471"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.75e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"3.3","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"9.1","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"1.6","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"28.3","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"15.9","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"2.5","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"2.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"4.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"2.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"1.6","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PRKRA","Gene synonym":["DYT16","HSD14","PACT","RAX"],"Ensembl":"ENSG00000180228","Gene description":"Protein activator of interferon induced protein kinase EIF2AK2","Uniprot":["O75569"],"Chromosome":"2","Position":"178431292-178451512","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","RNA-mediated gene silencing"],"Molecular function":["RNA-binding"],"Disease involvement":["Disease variant","Dystonia","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"307.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004648","HPA034996","HPA034997"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB004648":"AB_425767","HPA034996":"AB_2674402","HPA034997":"AB_2674403"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.33e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.45e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.7","Tissue RNA - adrenal gland [nTPM]":"21.9","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"13.8","Tissue RNA - basal ganglia [nTPM]":"22.6","Tissue RNA - bone marrow [nTPM]":"18.2","Tissue RNA - breast [nTPM]":"26.4","Tissue RNA - cerebellum [nTPM]":"24.6","Tissue RNA - cerebral cortex [nTPM]":"31.3","Tissue RNA - cervix [nTPM]":"23.6","Tissue RNA - choroid plexus [nTPM]":"25.3","Tissue RNA - colon [nTPM]":"36.4","Tissue RNA - duodenum [nTPM]":"13.7","Tissue RNA - endometrium 1 [nTPM]":"28.7","Tissue RNA - epididymis [nTPM]":"25.7","Tissue RNA - esophagus [nTPM]":"22.8","Tissue RNA - fallopian tube [nTPM]":"23.4","Tissue RNA - gallbladder [nTPM]":"17.5","Tissue RNA - heart muscle [nTPM]":"37.2","Tissue RNA - hippocampal formation [nTPM]":"22.8","Tissue RNA - hypothalamus [nTPM]":"24.9","Tissue RNA - kidney [nTPM]":"29.7","Tissue RNA - liver [nTPM]":"20.2","Tissue RNA - lung [nTPM]":"21.2","Tissue RNA - lymph node [nTPM]":"16.9","Tissue RNA - medulla oblongata [nTPM]":"25.0","Tissue RNA - midbrain [nTPM]":"22.5","Tissue RNA - ovary [nTPM]":"23.4","Tissue RNA - pancreas [nTPM]":"25.4","Tissue RNA - parathyroid gland [nTPM]":"26.2","Tissue RNA - pituitary gland [nTPM]":"22.5","Tissue RNA - placenta [nTPM]":"11.5","Tissue RNA - pons [nTPM]":"24.2","Tissue RNA - prostate [nTPM]":"23.4","Tissue RNA - rectum [nTPM]":"20.1","Tissue RNA - retina [nTPM]":"30.9","Tissue RNA - salivary gland [nTPM]":"22.6","Tissue RNA - seminal vesicle [nTPM]":"24.3","Tissue RNA - skeletal muscle [nTPM]":"100.7","Tissue RNA - skin 1 [nTPM]":"31.2","Tissue RNA - small intestine [nTPM]":"19.7","Tissue RNA - smooth muscle [nTPM]":"29.4","Tissue RNA - spinal cord [nTPM]":"25.2","Tissue RNA - spleen [nTPM]":"15.9","Tissue RNA - stomach 1 [nTPM]":"26.0","Tissue RNA - testis [nTPM]":"24.3","Tissue RNA - thalamus [nTPM]":"23.1","Tissue RNA - thymus [nTPM]":"20.4","Tissue RNA - thyroid gland [nTPM]":"22.1","Tissue RNA - tongue [nTPM]":"72.7","Tissue RNA - tonsil [nTPM]":"20.4","Tissue RNA - urinary bladder [nTPM]":"32.1","Tissue RNA - vagina [nTPM]":"22.0","Tissue RNA - white matter [nTPM]":"27.1","Cell RNA - A-431 [nTPM]":"24.6","Cell RNA - A549 [nTPM]":"18.4","Cell RNA - AF22 [nTPM]":"48.2","Cell RNA - AN3-CA [nTPM]":"20.8","Cell RNA - ASC diff [nTPM]":"49.2","Cell RNA - ASC TERT1 [nTPM]":"56.7","Cell RNA - BEWO [nTPM]":"39.6","Cell RNA - BJ [nTPM]":"35.4","Cell RNA - BJ hTERT+ [nTPM]":"37.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"50.8","Cell RNA - CACO-2 [nTPM]":"50.9","Cell RNA - CAPAN-2 [nTPM]":"33.8","Cell RNA - Daudi [nTPM]":"51.0","Cell RNA - EFO-21 [nTPM]":"39.8","Cell RNA - fHDF\/TERT166 [nTPM]":"43.6","Cell RNA - GAMG [nTPM]":"30.9","Cell RNA - HaCaT [nTPM]":"21.0","Cell RNA - HAP1 [nTPM]":"42.0","Cell RNA - HBEC3-KT [nTPM]":"28.5","Cell RNA - HBF TERT88 [nTPM]":"50.9","Cell RNA - HDLM-2 [nTPM]":"43.9","Cell RNA - HEK 293 [nTPM]":"25.0","Cell RNA - HEL [nTPM]":"29.2","Cell RNA - HeLa [nTPM]":"17.0","Cell RNA - Hep G2 [nTPM]":"46.7","Cell RNA - HHSteC [nTPM]":"58.6","Cell RNA - HL-60 [nTPM]":"21.2","Cell RNA - HMC-1 [nTPM]":"16.1","Cell RNA - HSkMC [nTPM]":"32.2","Cell RNA - hTCEpi [nTPM]":"69.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.0","Cell RNA - hTERT-HME1 [nTPM]":"49.7","Cell RNA - hTERT-RPE1 [nTPM]":"46.0","Cell RNA - HUVEC TERT2 [nTPM]":"46.8","Cell RNA - JURKAT [nTPM]":"32.8","Cell RNA - K-562 [nTPM]":"26.7","Cell RNA - Karpas-707 [nTPM]":"34.9","Cell RNA - LHCN-M2 [nTPM]":"62.9","Cell RNA - MCF7 [nTPM]":"25.3","Cell RNA - MOLT-4 [nTPM]":"46.3","Cell RNA - NB-4 [nTPM]":"52.2","Cell RNA - NTERA-2 [nTPM]":"46.7","Cell RNA - OE19 [nTPM]":"42.3","Cell RNA - PC-3 [nTPM]":"33.5","Cell RNA - REH [nTPM]":"38.5","Cell RNA - RH-30 [nTPM]":"89.0","Cell RNA - RPMI-8226 [nTPM]":"46.6","Cell RNA - RPTEC TERT1 [nTPM]":"52.4","Cell RNA - RT4 [nTPM]":"25.5","Cell RNA - SCLC-21H [nTPM]":"30.2","Cell RNA - SH-SY5Y [nTPM]":"39.4","Cell RNA - SiHa [nTPM]":"21.9","Cell RNA - SK-BR-3 [nTPM]":"20.2","Cell RNA - SK-MEL-30 [nTPM]":"48.3","Cell RNA - SuSa [nTPM]":"36.3","Cell RNA - T-47d [nTPM]":"30.6","Cell RNA - THP-1 [nTPM]":"27.4","Cell RNA - TIME [nTPM]":"20.8","Cell RNA - U-138 MG [nTPM]":"32.0","Cell RNA - U-2 OS [nTPM]":"42.6","Cell RNA - U-2197 [nTPM]":"33.8","Cell RNA - U-251 MG [nTPM]":"29.9","Cell RNA - U-266\/70 [nTPM]":"52.5","Cell RNA - U-266\/84 [nTPM]":"33.7","Cell RNA - U-698 [nTPM]":"62.6","Cell RNA - U-87 MG [nTPM]":"40.8","Cell RNA - U-937 [nTPM]":"35.1","Cell RNA - WM-115 [nTPM]":"20.7","Blood RNA - basophil [nTPM]":"5.4","Blood RNA - classical monocyte [nTPM]":"24.7","Blood RNA - eosinophil [nTPM]":"25.9","Blood RNA - gdT-cell [nTPM]":"18.1","Blood RNA - intermediate monocyte [nTPM]":"25.5","Blood RNA - MAIT T-cell [nTPM]":"26.2","Blood RNA - memory B-cell [nTPM]":"34.3","Blood RNA - memory CD4 T-cell [nTPM]":"28.4","Blood RNA - memory CD8 T-cell [nTPM]":"22.7","Blood RNA - myeloid DC [nTPM]":"37.2","Blood RNA - naive B-cell [nTPM]":"26.4","Blood RNA - naive CD4 T-cell [nTPM]":"31.4","Blood RNA - naive CD8 T-cell [nTPM]":"25.8","Blood RNA - neutrophil [nTPM]":"5.1","Blood RNA - NK-cell [nTPM]":"25.2","Blood RNA - non-classical monocyte [nTPM]":"26.3","Blood RNA - plasmacytoid DC [nTPM]":"49.7","Blood RNA - T-reg [nTPM]":"38.3","Blood RNA - total PBMC [nTPM]":"30.9","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"22.6","Brain RNA - cerebellum [nTPM]":"24.6","Brain RNA - cerebral cortex [nTPM]":"31.3","Brain RNA - hippocampal formation [nTPM]":"22.8","Brain RNA - hypothalamus [nTPM]":"24.9","Brain RNA - medulla oblongata [nTPM]":"25.0","Brain RNA - midbrain [nTPM]":"22.5","Brain RNA - pons [nTPM]":"24.2","Brain RNA - spinal cord [nTPM]":"25.2","Brain RNA - thalamus [nTPM]":"23.1","Brain RNA - white matter [nTPM]":"27.1","Single Cell Type RNA - Adipocytes [nTPM]":"35.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.4","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"37.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"63.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"90.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"89.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"53.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"40.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"39.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.7","Single Cell Type RNA - dendritic cells [nTPM]":"49.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"125.2","Single Cell Type RNA - Ductal cells [nTPM]":"51.4","Single Cell Type RNA - Early spermatids [nTPM]":"149.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.2","Single Cell Type RNA - Endothelial cells [nTPM]":"34.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"47.9","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"41.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"53.2","Single Cell Type RNA - Fibroblasts [nTPM]":"42.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.0","Single Cell Type RNA - granulocytes [nTPM]":"28.5","Single Cell Type RNA - Granulosa cells [nTPM]":"40.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"18.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.4","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.5","Single Cell Type RNA - Ionocytes [nTPM]":"93.6","Single Cell Type RNA - Kupffer cells [nTPM]":"19.8","Single Cell Type RNA - Langerhans cells [nTPM]":"69.4","Single Cell Type RNA - Late spermatids [nTPM]":"307.9","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"26.4","Single Cell Type RNA - Melanocytes [nTPM]":"69.4","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"38.6","Single Cell Type RNA - Muller glia cells [nTPM]":"49.2","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.0","Single Cell Type RNA - Paneth cells [nTPM]":"25.1","Single Cell Type RNA - Peritubular cells [nTPM]":"37.2","Single Cell Type RNA - Plasma cells [nTPM]":"42.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"94.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"89.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"86.2","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"66.7","Single Cell Type RNA - Spermatocytes [nTPM]":"78.7","Single Cell Type RNA - Spermatogonia [nTPM]":"57.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"78.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"43.4","Single Cell Type RNA - T-cells [nTPM]":"33.6","Single Cell Type RNA - Theca cells [nTPM]":"47.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.6","Single Cell Type RNA - Urothelial cells [nTPM]":"73.0"},{"Gene":"PRNP","Gene synonym":["AltPrP","CD230","CJD","GSS","PRIP","PRP"],"Ensembl":"ENSG00000171867","Gene description":"Prion protein","Uniprot":["P04156"],"Chromosome":"20","Position":"4686350-4701590","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell cycle","Growth arrest"],"Molecular function":["Prion"],"Disease involvement":["Amyloidosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"412.6","Basal squamous epithelial cells":"369.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"875.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"875.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"WM-115":"1039.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042754","HPA043398"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5100000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nuclear membrane","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA042754":"AB_10964203","HPA043398":"AB_2678461"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.96e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"87.0","Tissue RNA - adrenal gland [nTPM]":"92.4","Tissue RNA - amygdala [nTPM]":"283.8","Tissue RNA - appendix [nTPM]":"52.4","Tissue RNA - basal ganglia [nTPM]":"308.4","Tissue RNA - bone marrow [nTPM]":"83.7","Tissue RNA - breast [nTPM]":"106.7","Tissue RNA - cerebellum [nTPM]":"255.1","Tissue RNA - cerebral cortex [nTPM]":"385.9","Tissue RNA - cervix [nTPM]":"135.4","Tissue RNA - choroid plexus [nTPM]":"415.8","Tissue RNA - colon [nTPM]":"184.2","Tissue RNA - duodenum [nTPM]":"37.1","Tissue RNA - endometrium 1 [nTPM]":"125.5","Tissue RNA - epididymis [nTPM]":"59.1","Tissue RNA - esophagus [nTPM]":"79.2","Tissue RNA - fallopian tube [nTPM]":"79.9","Tissue RNA - gallbladder [nTPM]":"110.1","Tissue RNA - heart muscle [nTPM]":"197.5","Tissue RNA - hippocampal formation [nTPM]":"315.6","Tissue RNA - hypothalamus [nTPM]":"244.8","Tissue RNA - kidney [nTPM]":"132.8","Tissue RNA - liver [nTPM]":"79.7","Tissue RNA - lung [nTPM]":"79.2","Tissue RNA - lymph node [nTPM]":"59.8","Tissue RNA - medulla oblongata [nTPM]":"262.8","Tissue RNA - midbrain [nTPM]":"260.8","Tissue RNA - ovary [nTPM]":"163.7","Tissue RNA - pancreas [nTPM]":"41.5","Tissue RNA - parathyroid gland [nTPM]":"62.8","Tissue RNA - pituitary gland [nTPM]":"83.8","Tissue RNA - placenta [nTPM]":"66.9","Tissue RNA - pons [nTPM]":"270.1","Tissue RNA - prostate [nTPM]":"146.1","Tissue RNA - rectum [nTPM]":"70.5","Tissue RNA - retina [nTPM]":"178.6","Tissue RNA - salivary gland [nTPM]":"60.3","Tissue RNA - seminal vesicle [nTPM]":"148.2","Tissue RNA - skeletal muscle [nTPM]":"64.0","Tissue RNA - skin 1 [nTPM]":"95.4","Tissue RNA - small intestine [nTPM]":"47.4","Tissue RNA - smooth muscle [nTPM]":"140.8","Tissue RNA - spinal cord [nTPM]":"265.0","Tissue RNA - spleen [nTPM]":"75.2","Tissue RNA - stomach 1 [nTPM]":"61.6","Tissue RNA - testis [nTPM]":"68.1","Tissue RNA - thalamus [nTPM]":"302.5","Tissue RNA - thymus [nTPM]":"47.9","Tissue RNA - thyroid gland [nTPM]":"89.1","Tissue RNA - tongue [nTPM]":"74.0","Tissue RNA - tonsil [nTPM]":"60.0","Tissue RNA - urinary bladder [nTPM]":"124.9","Tissue RNA - vagina [nTPM]":"83.4","Tissue RNA - white matter [nTPM]":"292.8","Cell RNA - A-431 [nTPM]":"226.4","Cell RNA - A549 [nTPM]":"141.6","Cell RNA - AF22 [nTPM]":"41.7","Cell RNA - AN3-CA [nTPM]":"64.2","Cell RNA - ASC diff [nTPM]":"329.6","Cell RNA - ASC TERT1 [nTPM]":"199.9","Cell RNA - BEWO [nTPM]":"36.6","Cell RNA - BJ [nTPM]":"363.4","Cell RNA - BJ hTERT+ [nTPM]":"527.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"175.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"177.7","Cell RNA - CACO-2 [nTPM]":"50.0","Cell RNA - CAPAN-2 [nTPM]":"171.5","Cell RNA - Daudi [nTPM]":"40.9","Cell RNA - EFO-21 [nTPM]":"79.2","Cell RNA - fHDF\/TERT166 [nTPM]":"727.9","Cell RNA - GAMG [nTPM]":"391.8","Cell RNA - HaCaT [nTPM]":"508.8","Cell RNA - HAP1 [nTPM]":"45.9","Cell RNA - HBEC3-KT [nTPM]":"498.3","Cell RNA - HBF TERT88 [nTPM]":"326.2","Cell RNA - HDLM-2 [nTPM]":"31.8","Cell RNA - HEK 293 [nTPM]":"39.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"19.6","Cell RNA - Hep G2 [nTPM]":"193.8","Cell RNA - HHSteC [nTPM]":"402.0","Cell RNA - HL-60 [nTPM]":"72.8","Cell RNA - HMC-1 [nTPM]":"16.5","Cell RNA - HSkMC [nTPM]":"177.5","Cell RNA - hTCEpi [nTPM]":"711.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"701.8","Cell RNA - hTERT-HME1 [nTPM]":"583.9","Cell RNA - hTERT-RPE1 [nTPM]":"257.0","Cell RNA - HUVEC TERT2 [nTPM]":"152.8","Cell RNA - JURKAT [nTPM]":"28.6","Cell RNA - K-562 [nTPM]":"22.8","Cell RNA - Karpas-707 [nTPM]":"142.9","Cell RNA - LHCN-M2 [nTPM]":"205.1","Cell RNA - MCF7 [nTPM]":"45.7","Cell RNA - MOLT-4 [nTPM]":"28.8","Cell RNA - NB-4 [nTPM]":"46.2","Cell RNA - NTERA-2 [nTPM]":"33.1","Cell RNA - OE19 [nTPM]":"99.8","Cell RNA - PC-3 [nTPM]":"266.4","Cell RNA - REH [nTPM]":"33.9","Cell RNA - RH-30 [nTPM]":"110.0","Cell RNA - RPMI-8226 [nTPM]":"38.3","Cell RNA - RPTEC TERT1 [nTPM]":"88.7","Cell RNA - RT4 [nTPM]":"40.3","Cell RNA - SCLC-21H [nTPM]":"49.2","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"98.9","Cell RNA - SK-BR-3 [nTPM]":"144.3","Cell RNA - SK-MEL-30 [nTPM]":"554.1","Cell RNA - SuSa [nTPM]":"56.4","Cell RNA - T-47d [nTPM]":"30.2","Cell RNA - THP-1 [nTPM]":"38.8","Cell RNA - TIME [nTPM]":"224.5","Cell RNA - U-138 MG [nTPM]":"282.9","Cell RNA - U-2 OS [nTPM]":"127.1","Cell RNA - U-2197 [nTPM]":"158.6","Cell RNA - U-251 MG [nTPM]":"296.1","Cell RNA - U-266\/70 [nTPM]":"63.1","Cell RNA - U-266\/84 [nTPM]":"129.5","Cell RNA - U-698 [nTPM]":"132.9","Cell RNA - U-87 MG [nTPM]":"226.8","Cell RNA - U-937 [nTPM]":"51.9","Cell RNA - WM-115 [nTPM]":"1039.0","Blood RNA - basophil [nTPM]":"875.9","Blood RNA - classical monocyte [nTPM]":"74.1","Blood RNA - eosinophil [nTPM]":"5.4","Blood RNA - gdT-cell [nTPM]":"67.3","Blood RNA - intermediate monocyte [nTPM]":"60.9","Blood RNA - MAIT T-cell [nTPM]":"100.7","Blood RNA - memory B-cell [nTPM]":"25.1","Blood RNA - memory CD4 T-cell [nTPM]":"56.9","Blood RNA - memory CD8 T-cell [nTPM]":"55.8","Blood RNA - myeloid DC [nTPM]":"62.9","Blood RNA - naive B-cell [nTPM]":"25.6","Blood RNA - naive CD4 T-cell [nTPM]":"33.5","Blood RNA - naive CD8 T-cell [nTPM]":"40.1","Blood RNA - neutrophil [nTPM]":"4.6","Blood RNA - NK-cell [nTPM]":"23.6","Blood RNA - non-classical monocyte [nTPM]":"50.4","Blood RNA - plasmacytoid DC [nTPM]":"24.6","Blood RNA - T-reg [nTPM]":"72.8","Blood RNA - total PBMC [nTPM]":"72.7","Brain RNA - amygdala [nTPM]":"283.8","Brain RNA - basal ganglia [nTPM]":"308.4","Brain RNA - cerebellum [nTPM]":"255.1","Brain RNA - cerebral cortex [nTPM]":"385.9","Brain RNA - hippocampal formation [nTPM]":"315.6","Brain RNA - hypothalamus [nTPM]":"244.8","Brain RNA - medulla oblongata [nTPM]":"262.8","Brain RNA - midbrain [nTPM]":"260.8","Brain RNA - pons [nTPM]":"270.1","Brain RNA - spinal cord [nTPM]":"265.0","Brain RNA - thalamus [nTPM]":"302.5","Brain RNA - white matter [nTPM]":"292.8","Single Cell Type RNA - Adipocytes [nTPM]":"44.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.4","Single Cell Type RNA - Astrocytes [nTPM]":"120.2","Single Cell Type RNA - B-cells [nTPM]":"85.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"412.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"211.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"132.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"369.3","Single Cell Type RNA - Bipolar cells [nTPM]":"265.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"60.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"103.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"257.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"68.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"116.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"71.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"58.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"73.2","Single Cell Type RNA - Endothelial cells [nTPM]":"66.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"29.9","Single Cell Type RNA - Erythroid cells [nTPM]":"31.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"125.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"177.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.2","Single Cell Type RNA - granulocytes [nTPM]":"173.0","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.0","Single Cell Type RNA - Hepatocytes [nTPM]":"36.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"63.6","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"170.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.4","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"219.1","Single Cell Type RNA - Langerhans cells [nTPM]":"200.4","Single Cell Type RNA - Late spermatids [nTPM]":"13.6","Single Cell Type RNA - Leydig cells [nTPM]":"143.2","Single Cell Type RNA - Macrophages [nTPM]":"126.3","Single Cell Type RNA - Melanocytes [nTPM]":"168.9","Single Cell Type RNA - Microglial cells [nTPM]":"59.0","Single Cell Type RNA - monocytes [nTPM]":"54.5","Single Cell Type RNA - Muller glia cells [nTPM]":"142.4","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"95.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"158.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.5","Single Cell Type RNA - Peritubular cells [nTPM]":"170.0","Single Cell Type RNA - Plasma cells [nTPM]":"47.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"120.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"84.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"99.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"73.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"82.3","Single Cell Type RNA - Spermatocytes [nTPM]":"36.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"81.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"284.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.4","Single Cell Type RNA - T-cells [nTPM]":"107.2","Single Cell Type RNA - Theca cells [nTPM]":"10.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.8","Single Cell Type RNA - Urothelial cells [nTPM]":"122.6"},{"Gene":"PROM1","Gene synonym":["AC133","CD133","CORD12","MCDR2","PROML1","RP41","STGD4"],"Ensembl":"ENSG00000007062","Gene description":"Prominin 1","Uniprot":["O43490"],"Chromosome":"4","Position":"15963076-16084378","Protein class":["CD markers","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant","Retinitis pigmentosa","Stargardt disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"272.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"581.7","Respiratory ciliated cells":"144.8","Rod photoreceptor cells":"311.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"37.2","CACO-2":"70.6","CAPAN-2":"28.9","EFO-21":"62.2","NTERA-2":"97.4","RPTEC TERT1":"91.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004922","CAB011525","HPA031053"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011525":"AB_470302","HPA004922":"AB_1846238","HPA031053":"AB_2673713"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"27.7","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"3.5","Tissue RNA - cervix [nTPM]":"44.9","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"30.7","Tissue RNA - duodenum [nTPM]":"12.4","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"30.9","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"20.9","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"4.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"14.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"30.1","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"16.7","Tissue RNA - retina [nTPM]":"272.9","Tissue RNA - salivary gland [nTPM]":"57.9","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"22.9","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"24.8","Tissue RNA - testis [nTPM]":"8.0","Tissue RNA - thalamus [nTPM]":"5.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"4.8","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"3.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"37.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"70.6","Cell RNA - CAPAN-2 [nTPM]":"28.9","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"62.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"7.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"97.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"91.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"12.0","Cell RNA - SH-SY5Y [nTPM]":"3.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"3.5","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"4.3","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"5.0","Brain RNA - white matter [nTPM]":"3.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"14.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"29.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"82.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"581.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"64.1","Single Cell Type RNA - Early spermatids [nTPM]":"31.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"71.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"44.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"47.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"45.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.2","Single Cell Type RNA - Paneth cells [nTPM]":"28.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"144.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"311.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"PRPF3","Gene synonym":["hPrp3","Prp3","RP18","SNRNP90"],"Ensembl":"ENSG00000117360","Gene description":"Pre-mRNA processing factor 3","Uniprot":["O43395"],"Chromosome":"1","Position":"150321479-150353233","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027226","HPA067116"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA027226":"AB_1855770","HPA067116":"AB_2685783"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.59e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.19e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-3"},"Tissue RNA - adipose tissue [nTPM]":"26.0","Tissue RNA - adrenal gland [nTPM]":"24.7","Tissue RNA - amygdala [nTPM]":"18.1","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"20.2","Tissue RNA - bone marrow [nTPM]":"44.8","Tissue RNA - breast [nTPM]":"27.0","Tissue RNA - cerebellum [nTPM]":"23.2","Tissue RNA - cerebral cortex [nTPM]":"23.1","Tissue RNA - cervix [nTPM]":"27.5","Tissue RNA - choroid plexus [nTPM]":"22.8","Tissue RNA - colon [nTPM]":"25.2","Tissue RNA - duodenum [nTPM]":"16.9","Tissue RNA - endometrium 1 [nTPM]":"25.0","Tissue RNA - epididymis [nTPM]":"26.7","Tissue RNA - esophagus [nTPM]":"22.2","Tissue RNA - fallopian tube [nTPM]":"25.7","Tissue RNA - gallbladder [nTPM]":"13.8","Tissue RNA - heart muscle [nTPM]":"19.5","Tissue RNA - hippocampal formation [nTPM]":"17.8","Tissue RNA - hypothalamus [nTPM]":"21.4","Tissue RNA - kidney [nTPM]":"29.0","Tissue RNA - liver [nTPM]":"30.4","Tissue RNA - lung [nTPM]":"24.3","Tissue RNA - lymph node [nTPM]":"28.6","Tissue RNA - medulla oblongata [nTPM]":"19.7","Tissue RNA - midbrain [nTPM]":"18.9","Tissue RNA - ovary [nTPM]":"34.1","Tissue RNA - pancreas [nTPM]":"23.8","Tissue RNA - parathyroid gland [nTPM]":"17.6","Tissue RNA - pituitary gland [nTPM]":"27.0","Tissue RNA - placenta [nTPM]":"20.9","Tissue RNA - pons [nTPM]":"19.3","Tissue RNA - prostate [nTPM]":"27.5","Tissue RNA - rectum [nTPM]":"19.6","Tissue RNA - retina [nTPM]":"43.5","Tissue RNA - salivary gland [nTPM]":"21.7","Tissue RNA - seminal vesicle [nTPM]":"19.5","Tissue RNA - skeletal muscle [nTPM]":"22.2","Tissue RNA - skin 1 [nTPM]":"23.8","Tissue RNA - small intestine [nTPM]":"24.6","Tissue RNA - smooth muscle [nTPM]":"18.7","Tissue RNA - spinal cord [nTPM]":"17.3","Tissue RNA - spleen [nTPM]":"33.8","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"20.1","Tissue RNA - thalamus [nTPM]":"19.7","Tissue RNA - thymus [nTPM]":"30.9","Tissue RNA - thyroid gland [nTPM]":"32.0","Tissue RNA - tongue [nTPM]":"14.9","Tissue RNA - tonsil [nTPM]":"28.5","Tissue RNA - urinary bladder [nTPM]":"24.3","Tissue RNA - vagina [nTPM]":"24.3","Tissue RNA - white matter [nTPM]":"21.6","Cell RNA - A-431 [nTPM]":"44.8","Cell RNA - A549 [nTPM]":"47.5","Cell RNA - AF22 [nTPM]":"47.1","Cell RNA - AN3-CA [nTPM]":"30.3","Cell RNA - ASC diff [nTPM]":"31.0","Cell RNA - ASC TERT1 [nTPM]":"33.5","Cell RNA - BEWO [nTPM]":"63.8","Cell RNA - BJ [nTPM]":"45.6","Cell RNA - BJ hTERT+ [nTPM]":"31.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"69.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.5","Cell RNA - CACO-2 [nTPM]":"36.6","Cell RNA - CAPAN-2 [nTPM]":"40.8","Cell RNA - Daudi [nTPM]":"58.7","Cell RNA - EFO-21 [nTPM]":"29.7","Cell RNA - fHDF\/TERT166 [nTPM]":"37.6","Cell RNA - GAMG [nTPM]":"64.4","Cell RNA - HaCaT [nTPM]":"51.5","Cell RNA - HAP1 [nTPM]":"86.1","Cell RNA - HBEC3-KT [nTPM]":"32.2","Cell RNA - HBF TERT88 [nTPM]":"61.7","Cell RNA - HDLM-2 [nTPM]":"29.7","Cell RNA - HEK 293 [nTPM]":"38.3","Cell RNA - HEL [nTPM]":"50.7","Cell RNA - HeLa [nTPM]":"72.1","Cell RNA - Hep G2 [nTPM]":"35.2","Cell RNA - HHSteC [nTPM]":"30.7","Cell RNA - HL-60 [nTPM]":"62.5","Cell RNA - HMC-1 [nTPM]":"31.6","Cell RNA - HSkMC [nTPM]":"24.6","Cell RNA - hTCEpi [nTPM]":"43.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"59.0","Cell RNA - hTERT-HME1 [nTPM]":"50.5","Cell RNA - hTERT-RPE1 [nTPM]":"32.9","Cell RNA - HUVEC TERT2 [nTPM]":"42.7","Cell RNA - JURKAT [nTPM]":"39.0","Cell RNA - K-562 [nTPM]":"61.3","Cell RNA - Karpas-707 [nTPM]":"34.8","Cell RNA - LHCN-M2 [nTPM]":"50.0","Cell RNA - MCF7 [nTPM]":"66.5","Cell RNA - MOLT-4 [nTPM]":"52.3","Cell RNA - NB-4 [nTPM]":"55.0","Cell RNA - NTERA-2 [nTPM]":"67.6","Cell RNA - OE19 [nTPM]":"114.3","Cell RNA - PC-3 [nTPM]":"41.9","Cell RNA - REH [nTPM]":"75.1","Cell RNA - RH-30 [nTPM]":"38.5","Cell RNA - RPMI-8226 [nTPM]":"38.8","Cell RNA - RPTEC TERT1 [nTPM]":"28.5","Cell RNA - RT4 [nTPM]":"26.7","Cell RNA - SCLC-21H [nTPM]":"40.3","Cell RNA - SH-SY5Y [nTPM]":"35.7","Cell RNA - SiHa [nTPM]":"37.9","Cell RNA - SK-BR-3 [nTPM]":"44.2","Cell RNA - SK-MEL-30 [nTPM]":"34.9","Cell RNA - SuSa [nTPM]":"63.3","Cell RNA - T-47d [nTPM]":"52.9","Cell RNA - THP-1 [nTPM]":"150.5","Cell RNA - TIME [nTPM]":"34.3","Cell RNA - U-138 MG [nTPM]":"43.2","Cell RNA - U-2 OS [nTPM]":"33.3","Cell RNA - U-2197 [nTPM]":"36.7","Cell RNA - U-251 MG [nTPM]":"75.8","Cell RNA - U-266\/70 [nTPM]":"33.1","Cell RNA - U-266\/84 [nTPM]":"62.8","Cell RNA - U-698 [nTPM]":"64.7","Cell RNA - U-87 MG [nTPM]":"28.8","Cell RNA - U-937 [nTPM]":"56.2","Cell RNA - WM-115 [nTPM]":"45.9","Blood RNA - basophil [nTPM]":"9.3","Blood RNA - classical monocyte [nTPM]":"9.0","Blood RNA - eosinophil [nTPM]":"13.3","Blood RNA - gdT-cell [nTPM]":"14.9","Blood RNA - intermediate monocyte [nTPM]":"11.8","Blood RNA - MAIT T-cell [nTPM]":"14.6","Blood RNA - memory B-cell [nTPM]":"13.0","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"9.8","Blood RNA - myeloid DC [nTPM]":"9.5","Blood RNA - naive B-cell [nTPM]":"10.0","Blood RNA - naive CD4 T-cell [nTPM]":"11.0","Blood RNA - naive CD8 T-cell [nTPM]":"11.4","Blood RNA - neutrophil [nTPM]":"5.3","Blood RNA - NK-cell [nTPM]":"11.5","Blood RNA - non-classical monocyte [nTPM]":"21.8","Blood RNA - plasmacytoid DC [nTPM]":"7.6","Blood RNA - T-reg [nTPM]":"9.1","Blood RNA - total PBMC [nTPM]":"8.3","Brain RNA - amygdala [nTPM]":"18.1","Brain RNA - basal ganglia [nTPM]":"20.2","Brain RNA - cerebellum [nTPM]":"23.2","Brain RNA - cerebral cortex [nTPM]":"23.1","Brain RNA - hippocampal formation [nTPM]":"17.8","Brain RNA - hypothalamus [nTPM]":"21.4","Brain RNA - medulla oblongata [nTPM]":"19.7","Brain RNA - midbrain [nTPM]":"18.9","Brain RNA - pons [nTPM]":"19.3","Brain RNA - spinal cord [nTPM]":"17.3","Brain RNA - thalamus [nTPM]":"19.7","Brain RNA - white matter [nTPM]":"21.6","Single Cell Type RNA - Adipocytes [nTPM]":"26.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.4","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"26.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"30.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"19.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.1","Single Cell Type RNA - dendritic cells [nTPM]":"22.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"15.6","Single Cell Type RNA - Early spermatids [nTPM]":"11.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.0","Single Cell Type RNA - Endothelial cells [nTPM]":"22.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.0","Single Cell Type RNA - Fibroblasts [nTPM]":"16.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"22.8","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"11.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.1","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.6","Single Cell Type RNA - Langerhans cells [nTPM]":"11.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"14.5","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"14.2","Single Cell Type RNA - Muller glia cells [nTPM]":"27.8","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.5","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.2","Single Cell Type RNA - Spermatocytes [nTPM]":"44.3","Single Cell Type RNA - Spermatogonia [nTPM]":"23.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"24.0","Single Cell Type RNA - Theca cells [nTPM]":"11.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.6","Single Cell Type RNA - Urothelial cells [nTPM]":"10.0"},{"Gene":"PRPF31","Gene synonym":["hPrp31","NY-BR-99","PRP31","RP11","SNRNP61"],"Ensembl":"ENSG00000105618","Gene description":"Pre-mRNA processing factor 31","Uniprot":["Q8WWY3"],"Chromosome":"19","Position":"54115410-54131719","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Ribonucleoprotein","RNA-binding"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041939","HPA061873"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA041939":"AB_10793938","HPA061873":"AB_2684630"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.33e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"35.1","Tissue RNA - adrenal gland [nTPM]":"36.0","Tissue RNA - amygdala [nTPM]":"26.1","Tissue RNA - appendix [nTPM]":"24.3","Tissue RNA - basal ganglia [nTPM]":"27.5","Tissue RNA - bone marrow [nTPM]":"33.2","Tissue RNA - breast [nTPM]":"35.1","Tissue RNA - cerebellum [nTPM]":"26.6","Tissue RNA - cerebral cortex [nTPM]":"31.3","Tissue RNA - cervix [nTPM]":"39.6","Tissue RNA - choroid plexus [nTPM]":"26.9","Tissue RNA - colon [nTPM]":"42.3","Tissue RNA - duodenum [nTPM]":"23.1","Tissue RNA - endometrium 1 [nTPM]":"39.7","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"37.8","Tissue RNA - fallopian tube [nTPM]":"35.3","Tissue RNA - gallbladder [nTPM]":"18.9","Tissue RNA - heart muscle [nTPM]":"38.8","Tissue RNA - hippocampal formation [nTPM]":"26.7","Tissue RNA - hypothalamus [nTPM]":"26.1","Tissue RNA - kidney [nTPM]":"34.2","Tissue RNA - liver [nTPM]":"44.5","Tissue RNA - lung [nTPM]":"29.7","Tissue RNA - lymph node [nTPM]":"33.2","Tissue RNA - medulla oblongata [nTPM]":"27.0","Tissue RNA - midbrain [nTPM]":"26.3","Tissue RNA - ovary [nTPM]":"39.0","Tissue RNA - pancreas [nTPM]":"29.3","Tissue RNA - parathyroid gland [nTPM]":"28.6","Tissue RNA - pituitary gland [nTPM]":"33.7","Tissue RNA - placenta [nTPM]":"23.1","Tissue RNA - pons [nTPM]":"26.7","Tissue RNA - prostate [nTPM]":"37.6","Tissue RNA - rectum [nTPM]":"13.9","Tissue RNA - retina [nTPM]":"8.1","Tissue RNA - salivary gland [nTPM]":"33.9","Tissue RNA - seminal vesicle [nTPM]":"23.6","Tissue RNA - skeletal muscle [nTPM]":"48.2","Tissue RNA - skin 1 [nTPM]":"40.2","Tissue RNA - small intestine [nTPM]":"34.6","Tissue RNA - smooth muscle [nTPM]":"19.0","Tissue RNA - spinal cord [nTPM]":"25.5","Tissue RNA - spleen [nTPM]":"39.7","Tissue RNA - stomach 1 [nTPM]":"35.7","Tissue RNA - testis [nTPM]":"33.0","Tissue RNA - thalamus [nTPM]":"27.2","Tissue RNA - thymus [nTPM]":"26.3","Tissue RNA - thyroid gland [nTPM]":"36.5","Tissue RNA - tongue [nTPM]":"23.7","Tissue RNA - tonsil [nTPM]":"23.4","Tissue RNA - urinary bladder [nTPM]":"38.3","Tissue RNA - vagina [nTPM]":"35.6","Tissue RNA - white matter [nTPM]":"28.5","Cell RNA - A-431 [nTPM]":"83.7","Cell RNA - A549 [nTPM]":"169.4","Cell RNA - AF22 [nTPM]":"55.0","Cell RNA - AN3-CA [nTPM]":"89.8","Cell RNA - ASC diff [nTPM]":"34.6","Cell RNA - ASC TERT1 [nTPM]":"33.0","Cell RNA - BEWO [nTPM]":"59.4","Cell RNA - BJ [nTPM]":"68.3","Cell RNA - BJ hTERT+ [nTPM]":"53.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"74.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"72.5","Cell RNA - CACO-2 [nTPM]":"82.4","Cell RNA - CAPAN-2 [nTPM]":"63.8","Cell RNA - Daudi [nTPM]":"89.1","Cell RNA - EFO-21 [nTPM]":"54.2","Cell RNA - fHDF\/TERT166 [nTPM]":"49.9","Cell RNA - GAMG [nTPM]":"36.0","Cell RNA - HaCaT [nTPM]":"49.8","Cell RNA - HAP1 [nTPM]":"64.6","Cell RNA - HBEC3-KT [nTPM]":"78.6","Cell RNA - HBF TERT88 [nTPM]":"46.4","Cell RNA - HDLM-2 [nTPM]":"82.4","Cell RNA - HEK 293 [nTPM]":"298.4","Cell RNA - HEL [nTPM]":"66.6","Cell RNA - HeLa [nTPM]":"108.3","Cell RNA - Hep G2 [nTPM]":"97.0","Cell RNA - HHSteC [nTPM]":"51.7","Cell RNA - HL-60 [nTPM]":"120.9","Cell RNA - HMC-1 [nTPM]":"59.7","Cell RNA - HSkMC [nTPM]":"54.2","Cell RNA - hTCEpi [nTPM]":"36.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"62.3","Cell RNA - hTERT-HME1 [nTPM]":"43.1","Cell RNA - hTERT-RPE1 [nTPM]":"39.4","Cell RNA - HUVEC TERT2 [nTPM]":"79.4","Cell RNA - JURKAT [nTPM]":"74.4","Cell RNA - K-562 [nTPM]":"96.8","Cell RNA - Karpas-707 [nTPM]":"46.2","Cell RNA - LHCN-M2 [nTPM]":"49.9","Cell RNA - MCF7 [nTPM]":"82.8","Cell RNA - MOLT-4 [nTPM]":"103.3","Cell RNA - NB-4 [nTPM]":"64.1","Cell RNA - NTERA-2 [nTPM]":"53.4","Cell RNA - OE19 [nTPM]":"78.5","Cell RNA - PC-3 [nTPM]":"187.1","Cell RNA - REH [nTPM]":"89.2","Cell RNA - RH-30 [nTPM]":"71.7","Cell RNA - RPMI-8226 [nTPM]":"81.5","Cell RNA - RPTEC TERT1 [nTPM]":"51.8","Cell RNA - RT4 [nTPM]":"120.8","Cell RNA - SCLC-21H [nTPM]":"61.6","Cell RNA - SH-SY5Y [nTPM]":"72.8","Cell RNA - SiHa [nTPM]":"88.0","Cell RNA - SK-BR-3 [nTPM]":"83.2","Cell RNA - SK-MEL-30 [nTPM]":"44.7","Cell RNA - SuSa [nTPM]":"24.5","Cell RNA - T-47d [nTPM]":"52.3","Cell RNA - THP-1 [nTPM]":"62.5","Cell RNA - TIME [nTPM]":"81.2","Cell RNA - U-138 MG [nTPM]":"100.4","Cell RNA - U-2 OS [nTPM]":"84.7","Cell RNA - U-2197 [nTPM]":"43.6","Cell RNA - U-251 MG [nTPM]":"109.0","Cell RNA - U-266\/70 [nTPM]":"58.6","Cell RNA - U-266\/84 [nTPM]":"97.7","Cell RNA - U-698 [nTPM]":"98.5","Cell RNA - U-87 MG [nTPM]":"75.7","Cell RNA - U-937 [nTPM]":"81.9","Cell RNA - WM-115 [nTPM]":"71.0","Blood RNA - basophil [nTPM]":"25.0","Blood RNA - classical monocyte [nTPM]":"44.3","Blood RNA - eosinophil [nTPM]":"30.1","Blood RNA - gdT-cell [nTPM]":"47.9","Blood RNA - intermediate monocyte [nTPM]":"53.1","Blood RNA - MAIT T-cell [nTPM]":"51.8","Blood RNA - memory B-cell [nTPM]":"43.5","Blood RNA - memory CD4 T-cell [nTPM]":"47.2","Blood RNA - memory CD8 T-cell [nTPM]":"51.4","Blood RNA - myeloid DC [nTPM]":"52.9","Blood RNA - naive B-cell [nTPM]":"44.5","Blood RNA - naive CD4 T-cell [nTPM]":"39.7","Blood RNA - naive CD8 T-cell [nTPM]":"40.5","Blood RNA - neutrophil [nTPM]":"9.1","Blood RNA - NK-cell [nTPM]":"54.4","Blood RNA - non-classical monocyte [nTPM]":"48.6","Blood RNA - plasmacytoid DC [nTPM]":"45.6","Blood RNA - T-reg [nTPM]":"61.0","Blood RNA - total PBMC [nTPM]":"51.1","Brain RNA - amygdala [nTPM]":"26.1","Brain RNA - basal ganglia [nTPM]":"27.5","Brain RNA - cerebellum [nTPM]":"26.6","Brain RNA - cerebral cortex [nTPM]":"31.3","Brain RNA - hippocampal formation [nTPM]":"26.7","Brain RNA - hypothalamus [nTPM]":"26.1","Brain RNA - medulla oblongata [nTPM]":"27.0","Brain RNA - midbrain [nTPM]":"26.3","Brain RNA - pons [nTPM]":"26.7","Brain RNA - spinal cord [nTPM]":"25.5","Brain RNA - thalamus [nTPM]":"27.2","Brain RNA - white matter [nTPM]":"28.5","Single Cell Type RNA - Adipocytes [nTPM]":"38.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.7","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"35.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"42.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"38.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"96.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"46.7","Single Cell Type RNA - Bipolar cells [nTPM]":"31.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"54.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"95.0","Single Cell Type RNA - dendritic cells [nTPM]":"40.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"74.6","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.9","Single Cell Type RNA - Endothelial cells [nTPM]":"47.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.8","Single Cell Type RNA - Erythroid cells [nTPM]":"32.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"62.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"90.8","Single Cell Type RNA - Fibroblasts [nTPM]":"42.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.0","Single Cell Type RNA - granulocytes [nTPM]":"31.7","Single Cell Type RNA - Granulosa cells [nTPM]":"53.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"27.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"66.4","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.9","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"22.2","Single Cell Type RNA - Langerhans cells [nTPM]":"43.2","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"38.2","Single Cell Type RNA - Macrophages [nTPM]":"33.7","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"61.2","Single Cell Type RNA - Muller glia cells [nTPM]":"51.1","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"63.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.1","Single Cell Type RNA - Peritubular cells [nTPM]":"48.9","Single Cell Type RNA - Plasma cells [nTPM]":"34.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"46.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"62.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"43.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.2","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.4","Single Cell Type RNA - Spermatocytes [nTPM]":"125.2","Single Cell Type RNA - Spermatogonia [nTPM]":"77.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"42.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"76.2","Single Cell Type RNA - T-cells [nTPM]":"41.5","Single Cell Type RNA - Theca cells [nTPM]":"54.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.3","Single Cell Type RNA - Urothelial cells [nTPM]":"32.8"},{"Gene":"PRPF4","Gene synonym":["HPRP4","HPRP4P","PRP4","Prp4p","SNRNP60"],"Ensembl":"ENSG00000136875","Gene description":"Pre-mRNA processing factor 4","Uniprot":["O43172"],"Chromosome":"9","Position":"113275642-113294009","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021794","HPA022248"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA021794":"AB_1855772","HPA022248":"AB_1855773"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.35e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"15.2","Tissue RNA - basal ganglia [nTPM]":"9.5","Tissue RNA - bone marrow [nTPM]":"15.1","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"10.3","Tissue RNA - cerebral cortex [nTPM]":"10.9","Tissue RNA - cervix [nTPM]":"11.2","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"11.1","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"13.5","Tissue RNA - epididymis [nTPM]":"19.4","Tissue RNA - esophagus [nTPM]":"14.9","Tissue RNA - fallopian tube [nTPM]":"12.3","Tissue RNA - gallbladder [nTPM]":"10.3","Tissue RNA - heart muscle [nTPM]":"11.0","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"9.5","Tissue RNA - kidney [nTPM]":"15.4","Tissue RNA - liver [nTPM]":"16.2","Tissue RNA - lung [nTPM]":"9.4","Tissue RNA - lymph node [nTPM]":"15.6","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"8.9","Tissue RNA - ovary [nTPM]":"14.8","Tissue RNA - pancreas [nTPM]":"14.4","Tissue RNA - parathyroid gland [nTPM]":"25.4","Tissue RNA - pituitary gland [nTPM]":"12.2","Tissue RNA - placenta [nTPM]":"12.5","Tissue RNA - pons [nTPM]":"9.2","Tissue RNA - prostate [nTPM]":"13.3","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"13.1","Tissue RNA - salivary gland [nTPM]":"11.2","Tissue RNA - seminal vesicle [nTPM]":"11.1","Tissue RNA - skeletal muscle [nTPM]":"18.1","Tissue RNA - skin 1 [nTPM]":"14.6","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"13.2","Tissue RNA - spinal cord [nTPM]":"9.0","Tissue RNA - spleen [nTPM]":"11.6","Tissue RNA - stomach 1 [nTPM]":"10.3","Tissue RNA - testis [nTPM]":"11.6","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"16.9","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"15.2","Tissue RNA - tonsil [nTPM]":"17.6","Tissue RNA - urinary bladder [nTPM]":"16.7","Tissue RNA - vagina [nTPM]":"11.3","Tissue RNA - white matter [nTPM]":"9.6","Cell RNA - A-431 [nTPM]":"36.6","Cell RNA - A549 [nTPM]":"61.3","Cell RNA - AF22 [nTPM]":"40.3","Cell RNA - AN3-CA [nTPM]":"44.4","Cell RNA - ASC diff [nTPM]":"27.8","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"40.4","Cell RNA - BJ [nTPM]":"56.1","Cell RNA - BJ hTERT+ [nTPM]":"28.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"60.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"44.2","Cell RNA - CACO-2 [nTPM]":"60.4","Cell RNA - CAPAN-2 [nTPM]":"33.4","Cell RNA - Daudi [nTPM]":"76.5","Cell RNA - EFO-21 [nTPM]":"32.5","Cell RNA - fHDF\/TERT166 [nTPM]":"30.3","Cell RNA - GAMG [nTPM]":"62.2","Cell RNA - HaCaT [nTPM]":"81.8","Cell RNA - HAP1 [nTPM]":"84.9","Cell RNA - HBEC3-KT [nTPM]":"48.8","Cell RNA - HBF TERT88 [nTPM]":"66.2","Cell RNA - HDLM-2 [nTPM]":"54.2","Cell RNA - HEK 293 [nTPM]":"32.1","Cell RNA - HEL [nTPM]":"39.1","Cell RNA - HeLa [nTPM]":"50.4","Cell RNA - Hep G2 [nTPM]":"43.7","Cell RNA - HHSteC [nTPM]":"25.2","Cell RNA - HL-60 [nTPM]":"68.0","Cell RNA - HMC-1 [nTPM]":"34.2","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"32.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.1","Cell RNA - hTERT-HME1 [nTPM]":"59.9","Cell RNA - hTERT-RPE1 [nTPM]":"22.6","Cell RNA - HUVEC TERT2 [nTPM]":"28.9","Cell RNA - JURKAT [nTPM]":"41.8","Cell RNA - K-562 [nTPM]":"67.5","Cell RNA - Karpas-707 [nTPM]":"40.9","Cell RNA - LHCN-M2 [nTPM]":"51.2","Cell RNA - MCF7 [nTPM]":"57.3","Cell RNA - MOLT-4 [nTPM]":"65.1","Cell RNA - NB-4 [nTPM]":"47.9","Cell RNA - NTERA-2 [nTPM]":"63.9","Cell RNA - OE19 [nTPM]":"94.2","Cell RNA - PC-3 [nTPM]":"66.5","Cell RNA - REH [nTPM]":"59.4","Cell RNA - RH-30 [nTPM]":"95.9","Cell RNA - RPMI-8226 [nTPM]":"51.4","Cell RNA - RPTEC TERT1 [nTPM]":"26.0","Cell RNA - RT4 [nTPM]":"28.9","Cell RNA - SCLC-21H [nTPM]":"52.7","Cell RNA - SH-SY5Y [nTPM]":"35.5","Cell RNA - SiHa [nTPM]":"82.9","Cell RNA - SK-BR-3 [nTPM]":"44.0","Cell RNA - SK-MEL-30 [nTPM]":"26.0","Cell RNA - SuSa [nTPM]":"32.0","Cell RNA - T-47d [nTPM]":"68.3","Cell RNA - THP-1 [nTPM]":"35.0","Cell RNA - TIME [nTPM]":"29.8","Cell RNA - U-138 MG [nTPM]":"49.1","Cell RNA - U-2 OS [nTPM]":"37.3","Cell RNA - U-2197 [nTPM]":"63.0","Cell RNA - U-251 MG [nTPM]":"72.4","Cell RNA - U-266\/70 [nTPM]":"52.1","Cell RNA - U-266\/84 [nTPM]":"153.1","Cell RNA - U-698 [nTPM]":"73.3","Cell RNA - U-87 MG [nTPM]":"37.6","Cell RNA - U-937 [nTPM]":"42.9","Cell RNA - WM-115 [nTPM]":"63.8","Blood RNA - basophil [nTPM]":"27.4","Blood RNA - classical monocyte [nTPM]":"16.2","Blood RNA - eosinophil [nTPM]":"16.1","Blood RNA - gdT-cell [nTPM]":"14.7","Blood RNA - intermediate monocyte [nTPM]":"19.4","Blood RNA - MAIT T-cell [nTPM]":"17.1","Blood RNA - memory B-cell [nTPM]":"17.1","Blood RNA - memory CD4 T-cell [nTPM]":"14.4","Blood RNA - memory CD8 T-cell [nTPM]":"13.3","Blood RNA - myeloid DC [nTPM]":"20.4","Blood RNA - naive B-cell [nTPM]":"17.4","Blood RNA - naive CD4 T-cell [nTPM]":"14.5","Blood RNA - naive CD8 T-cell [nTPM]":"14.6","Blood RNA - neutrophil [nTPM]":"5.2","Blood RNA - NK-cell [nTPM]":"18.4","Blood RNA - non-classical monocyte [nTPM]":"24.6","Blood RNA - plasmacytoid DC [nTPM]":"13.4","Blood RNA - T-reg [nTPM]":"14.6","Blood RNA - total PBMC [nTPM]":"14.8","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"9.5","Brain RNA - cerebellum [nTPM]":"10.3","Brain RNA - cerebral cortex [nTPM]":"10.9","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"9.5","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"8.9","Brain RNA - pons [nTPM]":"9.2","Brain RNA - spinal cord [nTPM]":"9.0","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"9.6","Single Cell Type RNA - Adipocytes [nTPM]":"15.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.4","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"23.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"22.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"15.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.7","Single Cell Type RNA - dendritic cells [nTPM]":"26.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"18.6","Single Cell Type RNA - Early spermatids [nTPM]":"17.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.5","Single Cell Type RNA - Erythroid cells [nTPM]":"20.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.5","Single Cell Type RNA - Fibroblasts [nTPM]":"16.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.9","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"21.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"9.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.4","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.5","Single Cell Type RNA - Langerhans cells [nTPM]":"17.8","Single Cell Type RNA - Late spermatids [nTPM]":"13.0","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"20.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"27.3","Single Cell Type RNA - Muller glia cells [nTPM]":"22.7","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.5","Single Cell Type RNA - Paneth cells [nTPM]":"9.6","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"15.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.5","Single Cell Type RNA - Spermatocytes [nTPM]":"28.6","Single Cell Type RNA - Spermatogonia [nTPM]":"21.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.5","Single Cell Type RNA - T-cells [nTPM]":"20.0","Single Cell Type RNA - Theca cells [nTPM]":"24.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.0","Single Cell Type RNA - Urothelial cells [nTPM]":"16.9"},{"Gene":"PRPF6","Gene synonym":["ANT-1","bB152O15.1","C20orf14","hPrp6","Prp6","RP60","SNRNP102","TOM","U5-102K"],"Ensembl":"ENSG00000101161","Gene description":"Pre-mRNA processing factor 6","Uniprot":["O94906"],"Chromosome":"20","Position":"63981132-64033100","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047106"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA047106":"AB_10963084"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-3"},"Tissue RNA - adipose tissue [nTPM]":"44.0","Tissue RNA - adrenal gland [nTPM]":"32.2","Tissue RNA - amygdala [nTPM]":"33.6","Tissue RNA - appendix [nTPM]":"30.8","Tissue RNA - basal ganglia [nTPM]":"37.4","Tissue RNA - bone marrow [nTPM]":"33.3","Tissue RNA - breast [nTPM]":"40.1","Tissue RNA - cerebellum [nTPM]":"44.9","Tissue RNA - cerebral cortex [nTPM]":"37.1","Tissue RNA - cervix [nTPM]":"38.5","Tissue RNA - choroid plexus [nTPM]":"34.5","Tissue RNA - colon [nTPM]":"39.9","Tissue RNA - duodenum [nTPM]":"30.0","Tissue RNA - endometrium 1 [nTPM]":"43.5","Tissue RNA - epididymis [nTPM]":"27.9","Tissue RNA - esophagus [nTPM]":"38.9","Tissue RNA - fallopian tube [nTPM]":"49.3","Tissue RNA - gallbladder [nTPM]":"27.2","Tissue RNA - heart muscle [nTPM]":"39.0","Tissue RNA - hippocampal formation [nTPM]":"32.9","Tissue RNA - hypothalamus [nTPM]":"34.7","Tissue RNA - kidney [nTPM]":"35.3","Tissue RNA - liver [nTPM]":"29.8","Tissue RNA - lung [nTPM]":"32.1","Tissue RNA - lymph node [nTPM]":"40.9","Tissue RNA - medulla oblongata [nTPM]":"37.7","Tissue RNA - midbrain [nTPM]":"35.5","Tissue RNA - ovary [nTPM]":"50.6","Tissue RNA - pancreas [nTPM]":"44.2","Tissue RNA - parathyroid gland [nTPM]":"37.2","Tissue RNA - pituitary gland [nTPM]":"36.7","Tissue RNA - placenta [nTPM]":"30.9","Tissue RNA - pons [nTPM]":"37.1","Tissue RNA - prostate [nTPM]":"34.5","Tissue RNA - rectum [nTPM]":"25.9","Tissue RNA - retina [nTPM]":"36.4","Tissue RNA - salivary gland [nTPM]":"38.3","Tissue RNA - seminal vesicle [nTPM]":"36.4","Tissue RNA - skeletal muscle [nTPM]":"64.6","Tissue RNA - skin 1 [nTPM]":"58.3","Tissue RNA - small intestine [nTPM]":"38.1","Tissue RNA - smooth muscle [nTPM]":"29.7","Tissue RNA - spinal cord [nTPM]":"34.6","Tissue RNA - spleen [nTPM]":"40.9","Tissue RNA - stomach 1 [nTPM]":"37.3","Tissue RNA - testis [nTPM]":"41.0","Tissue RNA - thalamus [nTPM]":"35.5","Tissue RNA - thymus [nTPM]":"44.4","Tissue RNA - thyroid gland [nTPM]":"36.2","Tissue RNA - tongue [nTPM]":"37.1","Tissue RNA - tonsil [nTPM]":"40.5","Tissue RNA - urinary bladder [nTPM]":"40.5","Tissue RNA - vagina [nTPM]":"36.2","Tissue RNA - white matter [nTPM]":"46.8","Cell RNA - A-431 [nTPM]":"72.8","Cell RNA - A549 [nTPM]":"86.5","Cell RNA - AF22 [nTPM]":"62.3","Cell RNA - AN3-CA [nTPM]":"66.3","Cell RNA - ASC diff [nTPM]":"69.5","Cell RNA - ASC TERT1 [nTPM]":"48.6","Cell RNA - BEWO [nTPM]":"81.5","Cell RNA - BJ [nTPM]":"56.1","Cell RNA - BJ hTERT+ [nTPM]":"62.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"167.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"74.6","Cell RNA - CACO-2 [nTPM]":"233.6","Cell RNA - CAPAN-2 [nTPM]":"86.2","Cell RNA - Daudi [nTPM]":"90.9","Cell RNA - EFO-21 [nTPM]":"133.4","Cell RNA - fHDF\/TERT166 [nTPM]":"74.5","Cell RNA - GAMG [nTPM]":"107.1","Cell RNA - HaCaT [nTPM]":"110.0","Cell RNA - HAP1 [nTPM]":"101.2","Cell RNA - HBEC3-KT [nTPM]":"116.1","Cell RNA - HBF TERT88 [nTPM]":"88.7","Cell RNA - HDLM-2 [nTPM]":"44.0","Cell RNA - HEK 293 [nTPM]":"59.0","Cell RNA - HEL [nTPM]":"76.8","Cell RNA - HeLa [nTPM]":"112.7","Cell RNA - Hep G2 [nTPM]":"213.3","Cell RNA - HHSteC [nTPM]":"76.7","Cell RNA - HL-60 [nTPM]":"105.3","Cell RNA - HMC-1 [nTPM]":"102.3","Cell RNA - HSkMC [nTPM]":"55.2","Cell RNA - hTCEpi [nTPM]":"81.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"77.5","Cell RNA - hTERT-HME1 [nTPM]":"89.2","Cell RNA - hTERT-RPE1 [nTPM]":"59.9","Cell RNA - HUVEC TERT2 [nTPM]":"63.3","Cell RNA - JURKAT [nTPM]":"83.7","Cell RNA - K-562 [nTPM]":"76.2","Cell RNA - Karpas-707 [nTPM]":"76.6","Cell RNA - LHCN-M2 [nTPM]":"56.8","Cell RNA - MCF7 [nTPM]":"89.2","Cell RNA - MOLT-4 [nTPM]":"106.8","Cell RNA - NB-4 [nTPM]":"131.0","Cell RNA - NTERA-2 [nTPM]":"55.4","Cell RNA - OE19 [nTPM]":"114.4","Cell RNA - PC-3 [nTPM]":"106.7","Cell RNA - REH [nTPM]":"116.0","Cell RNA - RH-30 [nTPM]":"53.0","Cell RNA - RPMI-8226 [nTPM]":"87.3","Cell RNA - RPTEC TERT1 [nTPM]":"64.4","Cell RNA - RT4 [nTPM]":"71.9","Cell RNA - SCLC-21H [nTPM]":"61.8","Cell RNA - SH-SY5Y [nTPM]":"72.4","Cell RNA - SiHa [nTPM]":"108.6","Cell RNA - SK-BR-3 [nTPM]":"110.0","Cell RNA - SK-MEL-30 [nTPM]":"74.1","Cell RNA - SuSa [nTPM]":"43.2","Cell RNA - T-47d [nTPM]":"108.0","Cell RNA - THP-1 [nTPM]":"135.5","Cell RNA - TIME [nTPM]":"90.1","Cell RNA - U-138 MG [nTPM]":"96.2","Cell RNA - U-2 OS [nTPM]":"55.1","Cell RNA - U-2197 [nTPM]":"77.4","Cell RNA - U-251 MG [nTPM]":"104.6","Cell RNA - U-266\/70 [nTPM]":"63.7","Cell RNA - U-266\/84 [nTPM]":"66.5","Cell RNA - U-698 [nTPM]":"94.6","Cell RNA - U-87 MG [nTPM]":"70.3","Cell RNA - U-937 [nTPM]":"62.5","Cell RNA - WM-115 [nTPM]":"76.3","Blood RNA - basophil [nTPM]":"90.8","Blood RNA - classical monocyte [nTPM]":"59.7","Blood RNA - eosinophil [nTPM]":"73.7","Blood RNA - gdT-cell [nTPM]":"67.0","Blood RNA - intermediate monocyte [nTPM]":"62.7","Blood RNA - MAIT T-cell [nTPM]":"93.3","Blood RNA - memory B-cell [nTPM]":"67.1","Blood RNA - memory CD4 T-cell [nTPM]":"82.3","Blood RNA - memory CD8 T-cell [nTPM]":"72.5","Blood RNA - myeloid DC [nTPM]":"58.6","Blood RNA - naive B-cell [nTPM]":"58.4","Blood RNA - naive CD4 T-cell [nTPM]":"95.8","Blood RNA - naive CD8 T-cell [nTPM]":"80.9","Blood RNA - neutrophil [nTPM]":"50.3","Blood RNA - NK-cell [nTPM]":"130.5","Blood RNA - non-classical monocyte [nTPM]":"77.8","Blood RNA - plasmacytoid DC [nTPM]":"54.5","Blood RNA - T-reg [nTPM]":"79.7","Blood RNA - total PBMC [nTPM]":"92.3","Brain RNA - amygdala [nTPM]":"33.6","Brain RNA - basal ganglia [nTPM]":"37.4","Brain RNA - cerebellum [nTPM]":"44.9","Brain RNA - cerebral cortex [nTPM]":"37.1","Brain RNA - hippocampal formation [nTPM]":"32.9","Brain RNA - hypothalamus [nTPM]":"34.7","Brain RNA - medulla oblongata [nTPM]":"37.7","Brain RNA - midbrain [nTPM]":"35.5","Brain RNA - pons [nTPM]":"37.1","Brain RNA - spinal cord [nTPM]":"34.6","Brain RNA - thalamus [nTPM]":"35.5","Brain RNA - white matter [nTPM]":"46.8","Single Cell Type RNA - Adipocytes [nTPM]":"60.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.6","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"69.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"50.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"63.2","Single Cell Type RNA - Bipolar cells [nTPM]":"81.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"54.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"59.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"70.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"71.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"72.5","Single Cell Type RNA - dendritic cells [nTPM]":"53.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"43.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"82.2","Single Cell Type RNA - Ductal cells [nTPM]":"59.3","Single Cell Type RNA - Early spermatids [nTPM]":"49.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"70.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"66.8","Single Cell Type RNA - Endothelial cells [nTPM]":"55.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"52.7","Single Cell Type RNA - Erythroid cells [nTPM]":"43.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"56.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.6","Single Cell Type RNA - Fibroblasts [nTPM]":"51.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.0","Single Cell Type RNA - granulocytes [nTPM]":"91.2","Single Cell Type RNA - Granulosa cells [nTPM]":"49.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.9","Single Cell Type RNA - Hepatocytes [nTPM]":"55.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"46.3","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"60.6","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"44.8","Single Cell Type RNA - Langerhans cells [nTPM]":"34.1","Single Cell Type RNA - Late spermatids [nTPM]":"28.7","Single Cell Type RNA - Leydig cells [nTPM]":"58.1","Single Cell Type RNA - Macrophages [nTPM]":"49.9","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"79.7","Single Cell Type RNA - Muller glia cells [nTPM]":"86.5","Single Cell Type RNA - NK-cells [nTPM]":"57.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"65.9","Single Cell Type RNA - Paneth cells [nTPM]":"43.9","Single Cell Type RNA - Peritubular cells [nTPM]":"52.6","Single Cell Type RNA - Plasma cells [nTPM]":"67.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"58.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"65.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"87.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"112.7","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"68.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"61.9","Single Cell Type RNA - Spermatocytes [nTPM]":"120.6","Single Cell Type RNA - Spermatogonia [nTPM]":"118.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"59.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"46.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"94.5","Single Cell Type RNA - T-cells [nTPM]":"60.0","Single Cell Type RNA - Theca cells [nTPM]":"32.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.7","Single Cell Type RNA - Urothelial cells [nTPM]":"34.3"},{"Gene":"PRPF8","Gene synonym":["hPrp8","Prp8","PRPC8","RP13","SNRNP220"],"Ensembl":"ENSG00000174231","Gene description":"Pre-mRNA processing factor 8","Uniprot":["Q6P2Q9"],"Chromosome":"17","Position":"1650629-1684867","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Ribonucleoprotein","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"252.3","Rod photoreceptor cells":"293.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009941","CAB015457"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB009941":"AB_2171185","CAB015457":"AB_831685"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"78.5","Tissue RNA - adrenal gland [nTPM]":"128.7","Tissue RNA - amygdala [nTPM]":"82.6","Tissue RNA - appendix [nTPM]":"45.7","Tissue RNA - basal ganglia [nTPM]":"85.0","Tissue RNA - bone marrow [nTPM]":"70.5","Tissue RNA - breast [nTPM]":"78.6","Tissue RNA - cerebellum [nTPM]":"93.2","Tissue RNA - cerebral cortex [nTPM]":"121.3","Tissue RNA - cervix [nTPM]":"98.5","Tissue RNA - choroid plexus [nTPM]":"98.7","Tissue RNA - colon [nTPM]":"93.5","Tissue RNA - duodenum [nTPM]":"33.0","Tissue RNA - endometrium 1 [nTPM]":"94.5","Tissue RNA - epididymis [nTPM]":"44.1","Tissue RNA - esophagus [nTPM]":"85.3","Tissue RNA - fallopian tube [nTPM]":"94.2","Tissue RNA - gallbladder [nTPM]":"30.8","Tissue RNA - heart muscle [nTPM]":"100.9","Tissue RNA - hippocampal formation [nTPM]":"84.4","Tissue RNA - hypothalamus [nTPM]":"84.0","Tissue RNA - kidney [nTPM]":"78.2","Tissue RNA - liver [nTPM]":"91.2","Tissue RNA - lung [nTPM]":"84.2","Tissue RNA - lymph node [nTPM]":"52.8","Tissue RNA - medulla oblongata [nTPM]":"83.6","Tissue RNA - midbrain [nTPM]":"82.1","Tissue RNA - ovary [nTPM]":"131.6","Tissue RNA - pancreas [nTPM]":"78.3","Tissue RNA - parathyroid gland [nTPM]":"82.7","Tissue RNA - pituitary gland [nTPM]":"130.4","Tissue RNA - placenta [nTPM]":"44.7","Tissue RNA - pons [nTPM]":"86.2","Tissue RNA - prostate [nTPM]":"89.7","Tissue RNA - rectum [nTPM]":"44.5","Tissue RNA - retina [nTPM]":"115.6","Tissue RNA - salivary gland [nTPM]":"78.1","Tissue RNA - seminal vesicle [nTPM]":"49.1","Tissue RNA - skeletal muscle [nTPM]":"146.7","Tissue RNA - skin 1 [nTPM]":"92.6","Tissue RNA - small intestine [nTPM]":"84.2","Tissue RNA - smooth muscle [nTPM]":"51.7","Tissue RNA - spinal cord [nTPM]":"80.9","Tissue RNA - spleen [nTPM]":"98.2","Tissue RNA - stomach 1 [nTPM]":"80.5","Tissue RNA - testis [nTPM]":"100.1","Tissue RNA - thalamus [nTPM]":"81.5","Tissue RNA - thymus [nTPM]":"83.9","Tissue RNA - thyroid gland [nTPM]":"89.0","Tissue RNA - tongue [nTPM]":"80.1","Tissue RNA - tonsil [nTPM]":"61.6","Tissue RNA - urinary bladder [nTPM]":"96.9","Tissue RNA - vagina [nTPM]":"84.3","Tissue RNA - white matter [nTPM]":"88.0","Cell RNA - A-431 [nTPM]":"104.0","Cell RNA - A549 [nTPM]":"240.7","Cell RNA - AF22 [nTPM]":"149.0","Cell RNA - AN3-CA [nTPM]":"116.1","Cell RNA - ASC diff [nTPM]":"120.8","Cell RNA - ASC TERT1 [nTPM]":"90.4","Cell RNA - BEWO [nTPM]":"107.9","Cell RNA - BJ [nTPM]":"78.2","Cell RNA - BJ hTERT+ [nTPM]":"109.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"160.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"122.4","Cell RNA - CACO-2 [nTPM]":"208.2","Cell RNA - CAPAN-2 [nTPM]":"50.0","Cell RNA - Daudi [nTPM]":"150.0","Cell RNA - EFO-21 [nTPM]":"73.2","Cell RNA - fHDF\/TERT166 [nTPM]":"150.5","Cell RNA - GAMG [nTPM]":"113.4","Cell RNA - HaCaT [nTPM]":"152.9","Cell RNA - HAP1 [nTPM]":"356.3","Cell RNA - HBEC3-KT [nTPM]":"139.5","Cell RNA - HBF TERT88 [nTPM]":"181.6","Cell RNA - HDLM-2 [nTPM]":"99.4","Cell RNA - HEK 293 [nTPM]":"170.0","Cell RNA - HEL [nTPM]":"124.3","Cell RNA - HeLa [nTPM]":"187.1","Cell RNA - Hep G2 [nTPM]":"161.0","Cell RNA - HHSteC [nTPM]":"73.5","Cell RNA - HL-60 [nTPM]":"145.4","Cell RNA - HMC-1 [nTPM]":"138.9","Cell RNA - HSkMC [nTPM]":"86.0","Cell RNA - hTCEpi [nTPM]":"91.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"194.8","Cell RNA - hTERT-HME1 [nTPM]":"146.7","Cell RNA - hTERT-RPE1 [nTPM]":"84.5","Cell RNA - HUVEC TERT2 [nTPM]":"146.1","Cell RNA - JURKAT [nTPM]":"106.2","Cell RNA - K-562 [nTPM]":"121.1","Cell RNA - Karpas-707 [nTPM]":"126.6","Cell RNA - LHCN-M2 [nTPM]":"117.9","Cell RNA - MCF7 [nTPM]":"112.7","Cell RNA - MOLT-4 [nTPM]":"114.4","Cell RNA - NB-4 [nTPM]":"117.4","Cell RNA - NTERA-2 [nTPM]":"97.0","Cell RNA - OE19 [nTPM]":"97.7","Cell RNA - PC-3 [nTPM]":"74.4","Cell RNA - REH [nTPM]":"218.4","Cell RNA - RH-30 [nTPM]":"82.3","Cell RNA - RPMI-8226 [nTPM]":"80.7","Cell RNA - RPTEC TERT1 [nTPM]":"63.1","Cell RNA - RT4 [nTPM]":"121.1","Cell RNA - SCLC-21H [nTPM]":"71.0","Cell RNA - SH-SY5Y [nTPM]":"103.8","Cell RNA - SiHa [nTPM]":"145.0","Cell RNA - SK-BR-3 [nTPM]":"61.5","Cell RNA - SK-MEL-30 [nTPM]":"69.3","Cell RNA - SuSa [nTPM]":"121.6","Cell RNA - T-47d [nTPM]":"87.4","Cell RNA - THP-1 [nTPM]":"91.3","Cell RNA - TIME [nTPM]":"122.1","Cell RNA - U-138 MG [nTPM]":"91.7","Cell RNA - U-2 OS [nTPM]":"78.3","Cell RNA - U-2197 [nTPM]":"130.2","Cell RNA - U-251 MG [nTPM]":"176.1","Cell RNA - U-266\/70 [nTPM]":"46.6","Cell RNA - U-266\/84 [nTPM]":"46.7","Cell RNA - U-698 [nTPM]":"101.9","Cell RNA - U-87 MG [nTPM]":"81.6","Cell RNA - U-937 [nTPM]":"108.1","Cell RNA - WM-115 [nTPM]":"121.6","Blood RNA - basophil [nTPM]":"23.1","Blood RNA - classical monocyte [nTPM]":"8.9","Blood RNA - eosinophil [nTPM]":"10.1","Blood RNA - gdT-cell [nTPM]":"19.1","Blood RNA - intermediate monocyte [nTPM]":"14.4","Blood RNA - MAIT T-cell [nTPM]":"23.6","Blood RNA - memory B-cell [nTPM]":"17.5","Blood RNA - memory CD4 T-cell [nTPM]":"17.7","Blood RNA - memory CD8 T-cell [nTPM]":"20.9","Blood RNA - myeloid DC [nTPM]":"15.7","Blood RNA - naive B-cell [nTPM]":"18.3","Blood RNA - naive CD4 T-cell [nTPM]":"16.7","Blood RNA - naive CD8 T-cell [nTPM]":"20.0","Blood RNA - neutrophil [nTPM]":"9.0","Blood RNA - NK-cell [nTPM]":"14.2","Blood RNA - non-classical monocyte [nTPM]":"21.7","Blood RNA - plasmacytoid DC [nTPM]":"25.2","Blood RNA - T-reg [nTPM]":"23.2","Blood RNA - total PBMC [nTPM]":"11.2","Brain RNA - amygdala [nTPM]":"82.6","Brain RNA - basal ganglia [nTPM]":"85.0","Brain RNA - cerebellum [nTPM]":"93.2","Brain RNA - cerebral cortex [nTPM]":"121.3","Brain RNA - hippocampal formation [nTPM]":"84.4","Brain RNA - hypothalamus [nTPM]":"84.0","Brain RNA - medulla oblongata [nTPM]":"83.6","Brain RNA - midbrain [nTPM]":"82.1","Brain RNA - pons [nTPM]":"86.2","Brain RNA - spinal cord [nTPM]":"80.9","Brain RNA - thalamus [nTPM]":"81.5","Brain RNA - white matter [nTPM]":"88.0","Single Cell Type RNA - Adipocytes [nTPM]":"45.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"84.3","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"72.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"56.9","Single Cell Type RNA - Bipolar cells [nTPM]":"128.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"53.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"252.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.3","Single Cell Type RNA - dendritic cells [nTPM]":"66.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.5","Single Cell Type RNA - Early spermatids [nTPM]":"11.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.8","Single Cell Type RNA - Endothelial cells [nTPM]":"46.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.5","Single Cell Type RNA - Erythroid cells [nTPM]":"73.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"40.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.7","Single Cell Type RNA - Fibroblasts [nTPM]":"48.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.3","Single Cell Type RNA - granulocytes [nTPM]":"52.6","Single Cell Type RNA - Granulosa cells [nTPM]":"55.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.9","Single Cell Type RNA - Hepatocytes [nTPM]":"38.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.8","Single Cell Type RNA - Horizontal cells [nTPM]":"72.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.2","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"40.1","Single Cell Type RNA - Langerhans cells [nTPM]":"26.5","Single Cell Type RNA - Late spermatids [nTPM]":"11.2","Single Cell Type RNA - Leydig cells [nTPM]":"73.3","Single Cell Type RNA - Macrophages [nTPM]":"42.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"48.3","Single Cell Type RNA - Muller glia cells [nTPM]":"55.9","Single Cell Type RNA - NK-cells [nTPM]":"46.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"42.7","Single Cell Type RNA - Paneth cells [nTPM]":"36.5","Single Cell Type RNA - Peritubular cells [nTPM]":"52.3","Single Cell Type RNA - Plasma cells [nTPM]":"70.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"48.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"51.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"293.2","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"65.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.8","Single Cell Type RNA - Spermatocytes [nTPM]":"100.4","Single Cell Type RNA - Spermatogonia [nTPM]":"99.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"57.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.5","Single Cell Type RNA - T-cells [nTPM]":"62.8","Single Cell Type RNA - Theca cells [nTPM]":"50.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"50.3","Single Cell Type RNA - Urothelial cells [nTPM]":"31.5"},{"Gene":"PRPH","Gene synonym":["NEF4","PRPH1"],"Ensembl":"ENSG00000135406","Gene description":"Peripherin","Uniprot":["P41219"],"Chromosome":"12","Position":"49293252-49298686","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"53.6","intestine":"21.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"327.5","Late spermatids":"920.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"endometrial cancer":"1.6","glioma":"1.7","pancreatic cancer":"1.1","testis cancer":"1.5"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"medulla oblongata":"51.9","pons":"53.6","white matter":"15.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"AN3-CA":"367.0"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hypothalamus":"19.4","pons and medulla":"35.1"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"spinal cord":"256.8"},"Antibody":["CAB002437","HPA039277","HPA063887"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002437":"AB_563956","HPA039277":"AB_2676424","HPA063887":"AB_2685142"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.88e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-5"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"14.5","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"3.3","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"21.0","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"3.1","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"51.9","Tissue RNA - midbrain [nTPM]":"8.0","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"53.6","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"1.5","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"8.9","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"7.8","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"8.3","Tissue RNA - white matter [nTPM]":"15.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"367.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"1.3","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"3.7","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"2.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.2","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"86.6","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"51.9","Brain RNA - midbrain [nTPM]":"8.0","Brain RNA - pons [nTPM]":"53.6","Brain RNA - spinal cord [nTPM]":"7.8","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"15.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"327.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"92.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"920.2","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.1","Single Cell Type RNA - Spermatocytes [nTPM]":"96.1","Single Cell Type RNA - Spermatogonia [nTPM]":"19.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"PRPH2","Gene synonym":["CACD2","rd2","RDS","RP7","TSPAN22"],"Ensembl":"ENSG00000112619","Gene description":"Peripherin 2","Uniprot":["P23942"],"Chromosome":"6","Position":"42696598-42722597","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"48","RNA tissue specific nTPM":{"retina":"641.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"260.6","Rod photoreceptor cells":"482.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"3.0","ASC TERT1":"3.4","fHDF\/TERT166":"5.3","HHSteC":"7.8","HSkMC":"6.0","LHCN-M2":"3.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"hippocampal formation":"2.4"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029458"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029458":"AB_10602193"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"3.1","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"641.4","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"13.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"2.9","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"3.4","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"5.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"7.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"6.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"3.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"39.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"260.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"42.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"482.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PRPS1","Gene synonym":["CMTX5","DFN2","DFNX1"],"Ensembl":"ENSG00000147224","Gene description":"Phosphoribosyl pyrophosphate synthetase 1","Uniprot":["P60891"],"Chromosome":"X","Position":"107628428-107651993","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Nucleotide biosynthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Disease variant","Gout","Mental retardation","Neurodegeneration","Neuropathy","Non-syndromic deafness","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043760","HPA051269"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA043760":"AB_2678656","HPA051269":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.9","Tissue RNA - adrenal gland [nTPM]":"28.0","Tissue RNA - amygdala [nTPM]":"33.7","Tissue RNA - appendix [nTPM]":"30.2","Tissue RNA - basal ganglia [nTPM]":"35.0","Tissue RNA - bone marrow [nTPM]":"58.0","Tissue RNA - breast [nTPM]":"21.0","Tissue RNA - cerebellum [nTPM]":"32.4","Tissue RNA - cerebral cortex [nTPM]":"36.4","Tissue RNA - cervix [nTPM]":"20.0","Tissue RNA - choroid plexus [nTPM]":"59.3","Tissue RNA - colon [nTPM]":"19.0","Tissue RNA - duodenum [nTPM]":"11.0","Tissue RNA - endometrium 1 [nTPM]":"23.7","Tissue RNA - epididymis [nTPM]":"14.8","Tissue RNA - esophagus [nTPM]":"13.7","Tissue RNA - fallopian tube [nTPM]":"25.9","Tissue RNA - gallbladder [nTPM]":"13.9","Tissue RNA - heart muscle [nTPM]":"22.2","Tissue RNA - hippocampal formation [nTPM]":"33.7","Tissue RNA - hypothalamus [nTPM]":"39.6","Tissue RNA - kidney [nTPM]":"27.6","Tissue RNA - liver [nTPM]":"51.5","Tissue RNA - lung [nTPM]":"21.5","Tissue RNA - lymph node [nTPM]":"42.7","Tissue RNA - medulla oblongata [nTPM]":"35.4","Tissue RNA - midbrain [nTPM]":"39.1","Tissue RNA - ovary [nTPM]":"30.2","Tissue RNA - pancreas [nTPM]":"21.7","Tissue RNA - parathyroid gland [nTPM]":"27.2","Tissue RNA - pituitary gland [nTPM]":"23.2","Tissue RNA - placenta [nTPM]":"14.6","Tissue RNA - pons [nTPM]":"37.6","Tissue RNA - prostate [nTPM]":"21.3","Tissue RNA - rectum [nTPM]":"17.9","Tissue RNA - retina [nTPM]":"30.2","Tissue RNA - salivary gland [nTPM]":"16.3","Tissue RNA - seminal vesicle [nTPM]":"17.4","Tissue RNA - skeletal muscle [nTPM]":"49.1","Tissue RNA - skin 1 [nTPM]":"12.3","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"29.5","Tissue RNA - spinal cord [nTPM]":"34.2","Tissue RNA - spleen [nTPM]":"26.2","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"35.2","Tissue RNA - thymus [nTPM]":"52.0","Tissue RNA - thyroid gland [nTPM]":"44.1","Tissue RNA - tongue [nTPM]":"37.9","Tissue RNA - tonsil [nTPM]":"45.7","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"15.2","Tissue RNA - white matter [nTPM]":"34.4","Cell RNA - A-431 [nTPM]":"93.5","Cell RNA - A549 [nTPM]":"128.9","Cell RNA - AF22 [nTPM]":"56.4","Cell RNA - AN3-CA [nTPM]":"69.9","Cell RNA - ASC diff [nTPM]":"32.7","Cell RNA - ASC TERT1 [nTPM]":"26.5","Cell RNA - BEWO [nTPM]":"18.6","Cell RNA - BJ [nTPM]":"253.2","Cell RNA - BJ hTERT+ [nTPM]":"55.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"146.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"122.6","Cell RNA - CACO-2 [nTPM]":"55.5","Cell RNA - CAPAN-2 [nTPM]":"36.6","Cell RNA - Daudi [nTPM]":"156.9","Cell RNA - EFO-21 [nTPM]":"111.7","Cell RNA - fHDF\/TERT166 [nTPM]":"94.9","Cell RNA - GAMG [nTPM]":"104.1","Cell RNA - HaCaT [nTPM]":"36.6","Cell RNA - HAP1 [nTPM]":"176.0","Cell RNA - HBEC3-KT [nTPM]":"53.8","Cell RNA - HBF TERT88 [nTPM]":"148.3","Cell RNA - HDLM-2 [nTPM]":"79.9","Cell RNA - HEK 293 [nTPM]":"150.9","Cell RNA - HEL [nTPM]":"84.2","Cell RNA - HeLa [nTPM]":"140.0","Cell RNA - Hep G2 [nTPM]":"100.3","Cell RNA - HHSteC [nTPM]":"28.8","Cell RNA - HL-60 [nTPM]":"153.1","Cell RNA - HMC-1 [nTPM]":"55.6","Cell RNA - HSkMC [nTPM]":"28.2","Cell RNA - hTCEpi [nTPM]":"30.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"90.2","Cell RNA - hTERT-HME1 [nTPM]":"56.2","Cell RNA - hTERT-RPE1 [nTPM]":"96.7","Cell RNA - HUVEC TERT2 [nTPM]":"52.3","Cell RNA - JURKAT [nTPM]":"108.2","Cell RNA - K-562 [nTPM]":"137.4","Cell RNA - Karpas-707 [nTPM]":"183.5","Cell RNA - LHCN-M2 [nTPM]":"69.0","Cell RNA - MCF7 [nTPM]":"51.0","Cell RNA - MOLT-4 [nTPM]":"101.2","Cell RNA - NB-4 [nTPM]":"113.6","Cell RNA - NTERA-2 [nTPM]":"213.5","Cell RNA - OE19 [nTPM]":"77.2","Cell RNA - PC-3 [nTPM]":"141.4","Cell RNA - REH [nTPM]":"117.6","Cell RNA - RH-30 [nTPM]":"96.3","Cell RNA - RPMI-8226 [nTPM]":"125.4","Cell RNA - RPTEC TERT1 [nTPM]":"60.7","Cell RNA - RT4 [nTPM]":"54.2","Cell RNA - SCLC-21H [nTPM]":"96.2","Cell RNA - SH-SY5Y [nTPM]":"52.5","Cell RNA - SiHa [nTPM]":"131.5","Cell RNA - SK-BR-3 [nTPM]":"77.6","Cell RNA - SK-MEL-30 [nTPM]":"57.3","Cell RNA - SuSa [nTPM]":"106.4","Cell RNA - T-47d [nTPM]":"36.0","Cell RNA - THP-1 [nTPM]":"61.7","Cell RNA - TIME [nTPM]":"31.2","Cell RNA - U-138 MG [nTPM]":"93.2","Cell RNA - U-2 OS [nTPM]":"45.0","Cell RNA - U-2197 [nTPM]":"108.3","Cell RNA - U-251 MG [nTPM]":"109.1","Cell RNA - U-266\/70 [nTPM]":"61.8","Cell RNA - U-266\/84 [nTPM]":"115.1","Cell RNA - U-698 [nTPM]":"172.7","Cell RNA - U-87 MG [nTPM]":"50.1","Cell RNA - U-937 [nTPM]":"163.6","Cell RNA - WM-115 [nTPM]":"61.6","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"8.9","Blood RNA - eosinophil [nTPM]":"22.6","Blood RNA - gdT-cell [nTPM]":"26.0","Blood RNA - intermediate monocyte [nTPM]":"14.3","Blood RNA - MAIT T-cell [nTPM]":"30.8","Blood RNA - memory B-cell [nTPM]":"29.3","Blood RNA - memory CD4 T-cell [nTPM]":"31.7","Blood RNA - memory CD8 T-cell [nTPM]":"32.2","Blood RNA - myeloid DC [nTPM]":"11.4","Blood RNA - naive B-cell [nTPM]":"31.0","Blood RNA - naive CD4 T-cell [nTPM]":"36.1","Blood RNA - naive CD8 T-cell [nTPM]":"30.7","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"28.5","Blood RNA - non-classical monocyte [nTPM]":"15.7","Blood RNA - plasmacytoid DC [nTPM]":"16.3","Blood RNA - T-reg [nTPM]":"35.5","Blood RNA - total PBMC [nTPM]":"21.1","Brain RNA - amygdala [nTPM]":"33.7","Brain RNA - basal ganglia [nTPM]":"35.0","Brain RNA - cerebellum [nTPM]":"32.4","Brain RNA - cerebral cortex [nTPM]":"36.4","Brain RNA - hippocampal formation [nTPM]":"33.7","Brain RNA - hypothalamus [nTPM]":"39.6","Brain RNA - medulla oblongata [nTPM]":"35.4","Brain RNA - midbrain [nTPM]":"39.1","Brain RNA - pons [nTPM]":"37.6","Brain RNA - spinal cord [nTPM]":"34.2","Brain RNA - thalamus [nTPM]":"35.2","Brain RNA - white matter [nTPM]":"34.4","Single Cell Type RNA - Adipocytes [nTPM]":"21.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"44.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"28.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"29.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"18.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.3","Single Cell Type RNA - Endothelial cells [nTPM]":"18.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"52.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.5","Single Cell Type RNA - Fibroblasts [nTPM]":"22.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"13.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"57.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.3","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.6","Single Cell Type RNA - Langerhans cells [nTPM]":"34.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"16.8","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"24.9","Single Cell Type RNA - Muller glia cells [nTPM]":"20.0","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.7","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"35.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.6","Single Cell Type RNA - Spermatogonia [nTPM]":"10.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"45.0","Single Cell Type RNA - Theca cells [nTPM]":"19.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.0","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"PRRT2","Gene synonym":["DKFZp547J199","DSPB3","DYT10","EKD1","FICCA","FLJ25513","ICCA","IFITMD1","PKC"],"Ensembl":"ENSG00000167371","Gene description":"Proline rich transmembrane protein 2","Uniprot":["Q7Z6L0"],"Chromosome":"16","Position":"29811382-29815892","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dystonia","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"124.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"82.3","Cone photoreceptor cells":"31.3","Leydig cells":"36.1","Peritubular cells":"40.3","Rod photoreceptor cells":"37.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"NK-cell":"3.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"3.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"24.1","HeLa":"13.8","hTERT-RPE1":"14.0","REH":"17.6","U-138 MG":"14.5"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014447","HPA019203","HPA048045"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014447":"AB_1855786","HPA019203":"AB_2670097","HPA048045":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.4","Tissue RNA - adrenal gland [nTPM]":"10.5","Tissue RNA - amygdala [nTPM]":"32.9","Tissue RNA - appendix [nTPM]":"2.4","Tissue RNA - basal ganglia [nTPM]":"40.4","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"10.8","Tissue RNA - cerebellum [nTPM]":"70.7","Tissue RNA - cerebral cortex [nTPM]":"70.5","Tissue RNA - cervix [nTPM]":"79.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"33.9","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"39.5","Tissue RNA - epididymis [nTPM]":"8.6","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"47.0","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"15.6","Tissue RNA - hippocampal formation [nTPM]":"46.0","Tissue RNA - hypothalamus [nTPM]":"20.1","Tissue RNA - kidney [nTPM]":"8.7","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"12.9","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"8.0","Tissue RNA - ovary [nTPM]":"124.3","Tissue RNA - pancreas [nTPM]":"4.7","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"85.6","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"16.2","Tissue RNA - prostate [nTPM]":"39.1","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"13.9","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"24.5","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"12.4","Tissue RNA - testis [nTPM]":"14.6","Tissue RNA - thalamus [nTPM]":"29.2","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"10.6","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"34.1","Tissue RNA - vagina [nTPM]":"51.0","Tissue RNA - white matter [nTPM]":"34.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"24.1","Cell RNA - AN3-CA [nTPM]":"8.6","Cell RNA - ASC diff [nTPM]":"1.2","Cell RNA - ASC TERT1 [nTPM]":"4.2","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"4.4","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"1.6","Cell RNA - HAP1 [nTPM]":"3.4","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"4.1","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"1.7","Cell RNA - HeLa [nTPM]":"13.8","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"14.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"17.6","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"4.1","Cell RNA - SH-SY5Y [nTPM]":"4.3","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"2.1","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"7.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"14.5","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"1.4","Cell RNA - U-266\/70 [nTPM]":"3.7","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"5.3","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"32.9","Brain RNA - basal ganglia [nTPM]":"40.4","Brain RNA - cerebellum [nTPM]":"70.7","Brain RNA - cerebral cortex [nTPM]":"70.5","Brain RNA - hippocampal formation [nTPM]":"46.0","Brain RNA - hypothalamus [nTPM]":"20.1","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"8.0","Brain RNA - pons [nTPM]":"16.2","Brain RNA - spinal cord [nTPM]":"24.5","Brain RNA - thalamus [nTPM]":"29.2","Brain RNA - white matter [nTPM]":"34.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"82.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.4","Single Cell Type RNA - Endothelial cells [nTPM]":"5.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"11.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.8","Single Cell Type RNA - Leydig cells [nTPM]":"36.1","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"5.7","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"9.0","Single Cell Type RNA - Peritubular cells [nTPM]":"40.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"PRX","Gene synonym":["KIAA1620"],"Ensembl":"ENSG00000105227","Gene description":"Periaxin","Uniprot":["Q9BXM0"],"Chromosome":"19","Position":"40393766-40414793","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Dejerine-Sottas syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"34.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"17.8","Breast myoepithelial cells":"23.2","Cardiomyocytes":"15.4","Skeletal myocytes":"30.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"spinal cord":"114.2"},"Antibody":["HPA001868"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus","Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA001868":"AB_2172440"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"4.7","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"3.9","Tissue RNA - cerebellum [nTPM]":"5.2","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"4.2","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"3.1","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"6.7","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"34.6","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"5.4","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"3.8","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"4.9","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"2.2","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"4.9","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"3.7","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"5.7","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"9.6","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"4.3","Tissue RNA - vagina [nTPM]":"3.1","Tissue RNA - white matter [nTPM]":"4.1","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"2.1","Cell RNA - AN3-CA [nTPM]":"2.7","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"4.4","Cell RNA - BEWO [nTPM]":"2.6","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"1.2","Cell RNA - HaCaT [nTPM]":"0.9","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.8","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"3.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.2","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"1.6","Cell RNA - JURKAT [nTPM]":"2.9","Cell RNA - K-562 [nTPM]":"2.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"2.2","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"3.8","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"3.2","Cell RNA - RH-30 [nTPM]":"1.8","Cell RNA - RPMI-8226 [nTPM]":"1.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"1.8","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"2.3","Cell RNA - SK-MEL-30 [nTPM]":"2.0","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"3.2","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"1.4","Cell RNA - U-138 MG [nTPM]":"3.8","Cell RNA - U-2 OS [nTPM]":"2.9","Cell RNA - U-2197 [nTPM]":"1.6","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"5.0","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"1.2","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"5.2","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"5.4","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"4.9","Brain RNA - thalamus [nTPM]":"5.7","Brain RNA - white matter [nTPM]":"4.1","Single Cell Type RNA - Adipocytes [nTPM]":"17.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"9.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"PSEN1","Gene synonym":["AD3","FAD","PS1","S182"],"Ensembl":"ENSG00000080815","Gene description":"Presenilin 1","Uniprot":["P49768"],"Chromosome":"14","Position":"73136418-73223691","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Cell adhesion","Notch signaling pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cancer-related genes","Cardiomyopathy","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocytes":"395.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006844","HPA030760","HPA067496"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cell Junctions"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cell Junctions"],"Antibody RRID":{"CAB006844":null,"HPA030760":"AB_10696211","HPA067496":"AB_2685853"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.52e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.1","Tissue RNA - adrenal gland [nTPM]":"22.6","Tissue RNA - amygdala [nTPM]":"44.3","Tissue RNA - appendix [nTPM]":"26.5","Tissue RNA - basal ganglia [nTPM]":"80.7","Tissue RNA - bone marrow [nTPM]":"39.6","Tissue RNA - breast [nTPM]":"28.2","Tissue RNA - cerebellum [nTPM]":"62.4","Tissue RNA - cerebral cortex [nTPM]":"56.0","Tissue RNA - cervix [nTPM]":"28.1","Tissue RNA - choroid plexus [nTPM]":"48.9","Tissue RNA - colon [nTPM]":"49.5","Tissue RNA - duodenum [nTPM]":"50.2","Tissue RNA - endometrium 1 [nTPM]":"25.3","Tissue RNA - epididymis [nTPM]":"26.9","Tissue RNA - esophagus [nTPM]":"35.2","Tissue RNA - fallopian tube [nTPM]":"22.9","Tissue RNA - gallbladder [nTPM]":"31.7","Tissue RNA - heart muscle [nTPM]":"18.0","Tissue RNA - hippocampal formation [nTPM]":"47.4","Tissue RNA - hypothalamus [nTPM]":"51.6","Tissue RNA - kidney [nTPM]":"35.5","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"32.1","Tissue RNA - lymph node [nTPM]":"22.4","Tissue RNA - medulla oblongata [nTPM]":"73.0","Tissue RNA - midbrain [nTPM]":"63.8","Tissue RNA - ovary [nTPM]":"22.0","Tissue RNA - pancreas [nTPM]":"22.9","Tissue RNA - parathyroid gland [nTPM]":"35.1","Tissue RNA - pituitary gland [nTPM]":"11.6","Tissue RNA - placenta [nTPM]":"43.1","Tissue RNA - pons [nTPM]":"71.5","Tissue RNA - prostate [nTPM]":"24.3","Tissue RNA - rectum [nTPM]":"46.3","Tissue RNA - retina [nTPM]":"23.4","Tissue RNA - salivary gland [nTPM]":"22.9","Tissue RNA - seminal vesicle [nTPM]":"23.4","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"38.2","Tissue RNA - small intestine [nTPM]":"49.0","Tissue RNA - smooth muscle [nTPM]":"27.1","Tissue RNA - spinal cord [nTPM]":"55.7","Tissue RNA - spleen [nTPM]":"22.6","Tissue RNA - stomach 1 [nTPM]":"31.0","Tissue RNA - testis [nTPM]":"32.5","Tissue RNA - thalamus [nTPM]":"60.8","Tissue RNA - thymus [nTPM]":"26.2","Tissue RNA - thyroid gland [nTPM]":"36.9","Tissue RNA - tongue [nTPM]":"23.3","Tissue RNA - tonsil [nTPM]":"30.7","Tissue RNA - urinary bladder [nTPM]":"35.0","Tissue RNA - vagina [nTPM]":"19.2","Tissue RNA - white matter [nTPM]":"119.1","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"55.9","Cell RNA - AF22 [nTPM]":"50.6","Cell RNA - AN3-CA [nTPM]":"20.0","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"49.9","Cell RNA - BEWO [nTPM]":"46.7","Cell RNA - BJ [nTPM]":"52.5","Cell RNA - BJ hTERT+ [nTPM]":"60.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"52.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"66.7","Cell RNA - CACO-2 [nTPM]":"69.9","Cell RNA - CAPAN-2 [nTPM]":"88.9","Cell RNA - Daudi [nTPM]":"23.7","Cell RNA - EFO-21 [nTPM]":"34.1","Cell RNA - fHDF\/TERT166 [nTPM]":"50.5","Cell RNA - GAMG [nTPM]":"43.0","Cell RNA - HaCaT [nTPM]":"94.9","Cell RNA - HAP1 [nTPM]":"43.2","Cell RNA - HBEC3-KT [nTPM]":"40.1","Cell RNA - HBF TERT88 [nTPM]":"57.3","Cell RNA - HDLM-2 [nTPM]":"54.6","Cell RNA - HEK 293 [nTPM]":"26.7","Cell RNA - HEL [nTPM]":"27.1","Cell RNA - HeLa [nTPM]":"35.1","Cell RNA - Hep G2 [nTPM]":"34.4","Cell RNA - HHSteC [nTPM]":"63.8","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"50.7","Cell RNA - HSkMC [nTPM]":"50.4","Cell RNA - hTCEpi [nTPM]":"71.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.3","Cell RNA - hTERT-HME1 [nTPM]":"54.4","Cell RNA - hTERT-RPE1 [nTPM]":"48.5","Cell RNA - HUVEC TERT2 [nTPM]":"43.2","Cell RNA - JURKAT [nTPM]":"26.2","Cell RNA - K-562 [nTPM]":"31.0","Cell RNA - Karpas-707 [nTPM]":"46.6","Cell RNA - LHCN-M2 [nTPM]":"50.0","Cell RNA - MCF7 [nTPM]":"72.8","Cell RNA - MOLT-4 [nTPM]":"21.0","Cell RNA - NB-4 [nTPM]":"35.7","Cell RNA - NTERA-2 [nTPM]":"22.0","Cell RNA - OE19 [nTPM]":"64.5","Cell RNA - PC-3 [nTPM]":"40.4","Cell RNA - REH [nTPM]":"26.4","Cell RNA - RH-30 [nTPM]":"42.7","Cell RNA - RPMI-8226 [nTPM]":"30.2","Cell RNA - RPTEC TERT1 [nTPM]":"73.7","Cell RNA - RT4 [nTPM]":"76.5","Cell RNA - SCLC-21H [nTPM]":"28.1","Cell RNA - SH-SY5Y [nTPM]":"38.3","Cell RNA - SiHa [nTPM]":"57.4","Cell RNA - SK-BR-3 [nTPM]":"53.0","Cell RNA - SK-MEL-30 [nTPM]":"47.1","Cell RNA - SuSa [nTPM]":"45.4","Cell RNA - T-47d [nTPM]":"66.3","Cell RNA - THP-1 [nTPM]":"60.7","Cell RNA - TIME [nTPM]":"45.7","Cell RNA - U-138 MG [nTPM]":"53.1","Cell RNA - U-2 OS [nTPM]":"43.5","Cell RNA - U-2197 [nTPM]":"44.1","Cell RNA - U-251 MG [nTPM]":"25.3","Cell RNA - U-266\/70 [nTPM]":"30.3","Cell RNA - U-266\/84 [nTPM]":"47.9","Cell RNA - U-698 [nTPM]":"23.7","Cell RNA - U-87 MG [nTPM]":"44.9","Cell RNA - U-937 [nTPM]":"32.8","Cell RNA - WM-115 [nTPM]":"33.3","Blood RNA - basophil [nTPM]":"126.8","Blood RNA - classical monocyte [nTPM]":"94.5","Blood RNA - eosinophil [nTPM]":"96.3","Blood RNA - gdT-cell [nTPM]":"23.1","Blood RNA - intermediate monocyte [nTPM]":"106.0","Blood RNA - MAIT T-cell [nTPM]":"22.6","Blood RNA - memory B-cell [nTPM]":"23.1","Blood RNA - memory CD4 T-cell [nTPM]":"22.3","Blood RNA - memory CD8 T-cell [nTPM]":"19.0","Blood RNA - myeloid DC [nTPM]":"83.4","Blood RNA - naive B-cell [nTPM]":"31.8","Blood RNA - naive CD4 T-cell [nTPM]":"20.7","Blood RNA - naive CD8 T-cell [nTPM]":"20.1","Blood RNA - neutrophil [nTPM]":"129.3","Blood RNA - NK-cell [nTPM]":"42.8","Blood RNA - non-classical monocyte [nTPM]":"125.0","Blood RNA - plasmacytoid DC [nTPM]":"43.6","Blood RNA - T-reg [nTPM]":"37.0","Blood RNA - total PBMC [nTPM]":"70.3","Brain RNA - amygdala [nTPM]":"44.3","Brain RNA - basal ganglia [nTPM]":"80.7","Brain RNA - cerebellum [nTPM]":"62.4","Brain RNA - cerebral cortex [nTPM]":"56.0","Brain RNA - hippocampal formation [nTPM]":"47.4","Brain RNA - hypothalamus [nTPM]":"51.6","Brain RNA - medulla oblongata [nTPM]":"73.0","Brain RNA - midbrain [nTPM]":"63.8","Brain RNA - pons [nTPM]":"71.5","Brain RNA - spinal cord [nTPM]":"55.7","Brain RNA - thalamus [nTPM]":"60.8","Brain RNA - white matter [nTPM]":"119.1","Single Cell Type RNA - Adipocytes [nTPM]":"22.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.5","Single Cell Type RNA - Astrocytes [nTPM]":"35.9","Single Cell Type RNA - B-cells [nTPM]":"25.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"17.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"30.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.1","Single Cell Type RNA - dendritic cells [nTPM]":"30.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"79.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"27.1","Single Cell Type RNA - Early spermatids [nTPM]":"22.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.4","Single Cell Type RNA - Endothelial cells [nTPM]":"22.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.2","Single Cell Type RNA - Fibroblasts [nTPM]":"23.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.4","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"29.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"24.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.5","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"40.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"50.5","Single Cell Type RNA - Langerhans cells [nTPM]":"40.8","Single Cell Type RNA - Late spermatids [nTPM]":"12.9","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"52.3","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"51.8","Single Cell Type RNA - Muller glia cells [nTPM]":"13.8","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"395.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.2","Single Cell Type RNA - Paneth cells [nTPM]":"58.8","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"23.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"76.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.0","Single Cell Type RNA - Spermatocytes [nTPM]":"40.2","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.9","Single Cell Type RNA - T-cells [nTPM]":"21.6","Single Cell Type RNA - Theca cells [nTPM]":"18.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.3","Single Cell Type RNA - Urothelial cells [nTPM]":"51.5"},{"Gene":"PSEN2","Gene synonym":["AD3L","AD4","PS2","STM2"],"Ensembl":"ENSG00000143801","Gene description":"Presenilin 2","Uniprot":["P49810"],"Chromosome":"1","Position":"226870184-226927726","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Notch signaling pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cardiomyopathy","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"36.7","Syncytiotrophoblasts":"45.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.2","Tissue RNA - adrenal gland [nTPM]":"19.8","Tissue RNA - amygdala [nTPM]":"9.7","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"9.8","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"10.5","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"9.0","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"14.0","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"13.5","Tissue RNA - liver [nTPM]":"12.6","Tissue RNA - lung [nTPM]":"11.5","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"10.9","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"45.5","Tissue RNA - parathyroid gland [nTPM]":"18.1","Tissue RNA - pituitary gland [nTPM]":"17.1","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"10.8","Tissue RNA - prostate [nTPM]":"14.9","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"13.6","Tissue RNA - skeletal muscle [nTPM]":"26.5","Tissue RNA - skin 1 [nTPM]":"10.1","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"8.5","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"11.5","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"10.7","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"9.7","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"14.1","Cell RNA - A549 [nTPM]":"24.5","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"21.9","Cell RNA - ASC diff [nTPM]":"10.0","Cell RNA - ASC TERT1 [nTPM]":"3.5","Cell RNA - BEWO [nTPM]":"10.2","Cell RNA - BJ [nTPM]":"12.4","Cell RNA - BJ hTERT+ [nTPM]":"26.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.9","Cell RNA - CACO-2 [nTPM]":"13.8","Cell RNA - CAPAN-2 [nTPM]":"21.5","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"17.0","Cell RNA - fHDF\/TERT166 [nTPM]":"16.8","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"7.9","Cell RNA - HAP1 [nTPM]":"12.1","Cell RNA - HBEC3-KT [nTPM]":"11.9","Cell RNA - HBF TERT88 [nTPM]":"6.7","Cell RNA - HDLM-2 [nTPM]":"13.6","Cell RNA - HEK 293 [nTPM]":"20.7","Cell RNA - HEL [nTPM]":"8.7","Cell RNA - HeLa [nTPM]":"10.5","Cell RNA - Hep G2 [nTPM]":"12.0","Cell RNA - HHSteC [nTPM]":"15.4","Cell RNA - HL-60 [nTPM]":"7.5","Cell RNA - HMC-1 [nTPM]":"15.7","Cell RNA - HSkMC [nTPM]":"9.1","Cell RNA - hTCEpi [nTPM]":"13.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.9","Cell RNA - hTERT-HME1 [nTPM]":"10.4","Cell RNA - hTERT-RPE1 [nTPM]":"11.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.9","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"18.1","Cell RNA - Karpas-707 [nTPM]":"6.4","Cell RNA - LHCN-M2 [nTPM]":"10.0","Cell RNA - MCF7 [nTPM]":"14.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"8.2","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"22.0","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"22.6","Cell RNA - RPMI-8226 [nTPM]":"26.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.9","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"11.3","Cell RNA - SH-SY5Y [nTPM]":"18.3","Cell RNA - SiHa [nTPM]":"9.7","Cell RNA - SK-BR-3 [nTPM]":"30.6","Cell RNA - SK-MEL-30 [nTPM]":"51.6","Cell RNA - SuSa [nTPM]":"18.4","Cell RNA - T-47d [nTPM]":"26.5","Cell RNA - THP-1 [nTPM]":"13.1","Cell RNA - TIME [nTPM]":"8.5","Cell RNA - U-138 MG [nTPM]":"11.2","Cell RNA - U-2 OS [nTPM]":"8.9","Cell RNA - U-2197 [nTPM]":"9.9","Cell RNA - U-251 MG [nTPM]":"15.2","Cell RNA - U-266\/70 [nTPM]":"25.6","Cell RNA - U-266\/84 [nTPM]":"45.0","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"21.5","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"15.7","Blood RNA - basophil [nTPM]":"37.4","Blood RNA - classical monocyte [nTPM]":"8.7","Blood RNA - eosinophil [nTPM]":"18.4","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"9.7","Blood RNA - MAIT T-cell [nTPM]":"5.1","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"11.4","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"20.0","Blood RNA - non-classical monocyte [nTPM]":"30.2","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"9.7","Brain RNA - basal ganglia [nTPM]":"9.8","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"10.9","Brain RNA - pons [nTPM]":"10.8","Brain RNA - spinal cord [nTPM]":"8.5","Brain RNA - thalamus [nTPM]":"10.7","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"11.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.0","Single Cell Type RNA - Endothelial cells [nTPM]":"10.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.1","Single Cell Type RNA - Fibroblasts [nTPM]":"5.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.2","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"8.2","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"18.9","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"45.8","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"6.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"PTPRQ","Gene synonym":["DFNB84"],"Ensembl":"ENSG00000139304","Gene description":"Protein tyrosine phosphatase receptor type Q","Uniprot":[],"Chromosome":"12","Position":"80402178-80680273","Protein class":["Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"7.1","urinary bladder":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"16.0","Club cells":"4.4","Early spermatids":"10.9","Excitatory neurons":"11.2","Late spermatids":"4.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"4.9","BJ":"3.9","HBF TERT88":"2.6","RH-30":"2.9","RT4":"3.4","SiHa":"1.9","U-2197":"3.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053245"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA053245":"AB_2682087"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"1.6","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"1.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"4.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"3.9","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"2.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.9","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.9","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"3.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"10.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"PUM1","Gene synonym":["KIAA0099","PUMH1"],"Ensembl":"ENSG00000134644","Gene description":"Pumilio RNA binding family member 1","Uniprot":["Q14671"],"Chromosome":"1","Position":"30931506-31065991","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis","Translation regulation"],"Molecular function":["RNA-binding"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027424","HPA027449"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA027424":"AB_10602918","HPA027449":"AB_2672281"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.62e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Tissue RNA - adipose tissue [nTPM]":"27.8","Tissue RNA - adrenal gland [nTPM]":"26.0","Tissue RNA - amygdala [nTPM]":"33.4","Tissue RNA - appendix [nTPM]":"22.5","Tissue RNA - basal ganglia [nTPM]":"34.3","Tissue RNA - bone marrow [nTPM]":"52.0","Tissue RNA - breast [nTPM]":"31.9","Tissue RNA - cerebellum [nTPM]":"37.5","Tissue RNA - cerebral cortex [nTPM]":"37.8","Tissue RNA - cervix [nTPM]":"28.0","Tissue RNA - choroid plexus [nTPM]":"28.5","Tissue RNA - colon [nTPM]":"26.7","Tissue RNA - duodenum [nTPM]":"22.5","Tissue RNA - endometrium 1 [nTPM]":"32.2","Tissue RNA - epididymis [nTPM]":"29.3","Tissue RNA - esophagus [nTPM]":"25.7","Tissue RNA - fallopian tube [nTPM]":"35.0","Tissue RNA - gallbladder [nTPM]":"22.7","Tissue RNA - heart muscle [nTPM]":"28.6","Tissue RNA - hippocampal formation [nTPM]":"33.7","Tissue RNA - hypothalamus [nTPM]":"42.5","Tissue RNA - kidney [nTPM]":"28.7","Tissue RNA - liver [nTPM]":"25.9","Tissue RNA - lung [nTPM]":"25.6","Tissue RNA - lymph node [nTPM]":"26.2","Tissue RNA - medulla oblongata [nTPM]":"27.0","Tissue RNA - midbrain [nTPM]":"30.0","Tissue RNA - ovary [nTPM]":"40.3","Tissue RNA - pancreas [nTPM]":"27.5","Tissue RNA - parathyroid gland [nTPM]":"39.3","Tissue RNA - pituitary gland [nTPM]":"19.2","Tissue RNA - placenta [nTPM]":"32.4","Tissue RNA - pons [nTPM]":"28.0","Tissue RNA - prostate [nTPM]":"27.3","Tissue RNA - rectum [nTPM]":"29.4","Tissue RNA - retina [nTPM]":"38.4","Tissue RNA - salivary gland [nTPM]":"30.3","Tissue RNA - seminal vesicle [nTPM]":"28.0","Tissue RNA - skeletal muscle [nTPM]":"46.1","Tissue RNA - skin 1 [nTPM]":"32.7","Tissue RNA - small intestine [nTPM]":"22.6","Tissue RNA - smooth muscle [nTPM]":"31.6","Tissue RNA - spinal cord [nTPM]":"27.8","Tissue RNA - spleen [nTPM]":"25.7","Tissue RNA - stomach 1 [nTPM]":"26.3","Tissue RNA - testis [nTPM]":"18.4","Tissue RNA - thalamus [nTPM]":"45.5","Tissue RNA - thymus [nTPM]":"35.1","Tissue RNA - thyroid gland [nTPM]":"34.9","Tissue RNA - tongue [nTPM]":"38.3","Tissue RNA - tonsil [nTPM]":"26.1","Tissue RNA - urinary bladder [nTPM]":"27.1","Tissue RNA - vagina [nTPM]":"26.0","Tissue RNA - white matter [nTPM]":"31.5","Cell RNA - A-431 [nTPM]":"33.7","Cell RNA - A549 [nTPM]":"43.7","Cell RNA - AF22 [nTPM]":"70.4","Cell RNA - AN3-CA [nTPM]":"44.7","Cell RNA - ASC diff [nTPM]":"54.1","Cell RNA - ASC TERT1 [nTPM]":"46.5","Cell RNA - BEWO [nTPM]":"48.2","Cell RNA - BJ [nTPM]":"39.3","Cell RNA - BJ hTERT+ [nTPM]":"47.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"45.5","Cell RNA - CACO-2 [nTPM]":"46.0","Cell RNA - CAPAN-2 [nTPM]":"56.6","Cell RNA - Daudi [nTPM]":"39.3","Cell RNA - EFO-21 [nTPM]":"40.2","Cell RNA - fHDF\/TERT166 [nTPM]":"53.8","Cell RNA - GAMG [nTPM]":"25.2","Cell RNA - HaCaT [nTPM]":"48.2","Cell RNA - HAP1 [nTPM]":"58.3","Cell RNA - HBEC3-KT [nTPM]":"43.4","Cell RNA - HBF TERT88 [nTPM]":"51.4","Cell RNA - HDLM-2 [nTPM]":"33.2","Cell RNA - HEK 293 [nTPM]":"50.8","Cell RNA - HEL [nTPM]":"42.8","Cell RNA - HeLa [nTPM]":"50.7","Cell RNA - Hep G2 [nTPM]":"56.0","Cell RNA - HHSteC [nTPM]":"37.9","Cell RNA - HL-60 [nTPM]":"52.6","Cell RNA - HMC-1 [nTPM]":"39.2","Cell RNA - HSkMC [nTPM]":"50.0","Cell RNA - hTCEpi [nTPM]":"53.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"53.5","Cell RNA - hTERT-HME1 [nTPM]":"56.1","Cell RNA - hTERT-RPE1 [nTPM]":"52.8","Cell RNA - HUVEC TERT2 [nTPM]":"55.6","Cell RNA - JURKAT [nTPM]":"36.9","Cell RNA - K-562 [nTPM]":"60.0","Cell RNA - Karpas-707 [nTPM]":"36.1","Cell RNA - LHCN-M2 [nTPM]":"46.5","Cell RNA - MCF7 [nTPM]":"28.1","Cell RNA - MOLT-4 [nTPM]":"51.6","Cell RNA - NB-4 [nTPM]":"37.8","Cell RNA - NTERA-2 [nTPM]":"72.2","Cell RNA - OE19 [nTPM]":"42.0","Cell RNA - PC-3 [nTPM]":"30.2","Cell RNA - REH [nTPM]":"53.1","Cell RNA - RH-30 [nTPM]":"48.0","Cell RNA - RPMI-8226 [nTPM]":"42.3","Cell RNA - RPTEC TERT1 [nTPM]":"58.7","Cell RNA - RT4 [nTPM]":"50.0","Cell RNA - SCLC-21H [nTPM]":"58.0","Cell RNA - SH-SY5Y [nTPM]":"44.0","Cell RNA - SiHa [nTPM]":"54.5","Cell RNA - SK-BR-3 [nTPM]":"41.7","Cell RNA - SK-MEL-30 [nTPM]":"47.6","Cell RNA - SuSa [nTPM]":"77.6","Cell RNA - T-47d [nTPM]":"42.1","Cell RNA - THP-1 [nTPM]":"39.3","Cell RNA - TIME [nTPM]":"58.5","Cell RNA - U-138 MG [nTPM]":"33.2","Cell RNA - U-2 OS [nTPM]":"29.8","Cell RNA - U-2197 [nTPM]":"44.7","Cell RNA - U-251 MG [nTPM]":"39.7","Cell RNA - U-266\/70 [nTPM]":"28.8","Cell RNA - U-266\/84 [nTPM]":"28.3","Cell RNA - U-698 [nTPM]":"42.5","Cell RNA - U-87 MG [nTPM]":"29.7","Cell RNA - U-937 [nTPM]":"38.3","Cell RNA - WM-115 [nTPM]":"43.0","Blood RNA - basophil [nTPM]":"44.1","Blood RNA - classical monocyte [nTPM]":"31.3","Blood RNA - eosinophil [nTPM]":"24.8","Blood RNA - gdT-cell [nTPM]":"31.0","Blood RNA - intermediate monocyte [nTPM]":"30.3","Blood RNA - MAIT T-cell [nTPM]":"31.7","Blood RNA - memory B-cell [nTPM]":"23.9","Blood RNA - memory CD4 T-cell [nTPM]":"27.5","Blood RNA - memory CD8 T-cell [nTPM]":"30.3","Blood RNA - myeloid DC [nTPM]":"32.0","Blood RNA - naive B-cell [nTPM]":"21.1","Blood RNA - naive CD4 T-cell [nTPM]":"31.0","Blood RNA - naive CD8 T-cell [nTPM]":"32.0","Blood RNA - neutrophil [nTPM]":"19.6","Blood RNA - NK-cell [nTPM]":"37.9","Blood RNA - non-classical monocyte [nTPM]":"34.5","Blood RNA - plasmacytoid DC [nTPM]":"18.5","Blood RNA - T-reg [nTPM]":"35.9","Blood RNA - total PBMC [nTPM]":"31.0","Brain RNA - amygdala [nTPM]":"33.4","Brain RNA - basal ganglia [nTPM]":"34.3","Brain RNA - cerebellum [nTPM]":"37.5","Brain RNA - cerebral cortex [nTPM]":"37.8","Brain RNA - hippocampal formation [nTPM]":"33.7","Brain RNA - hypothalamus [nTPM]":"42.5","Brain RNA - medulla oblongata [nTPM]":"27.0","Brain RNA - midbrain [nTPM]":"30.0","Brain RNA - pons [nTPM]":"28.0","Brain RNA - spinal cord [nTPM]":"27.8","Brain RNA - thalamus [nTPM]":"45.5","Brain RNA - white matter [nTPM]":"31.5","Single Cell Type RNA - Adipocytes [nTPM]":"66.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.8","Single Cell Type RNA - Astrocytes [nTPM]":"85.2","Single Cell Type RNA - B-cells [nTPM]":"56.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"90.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"53.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"41.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"56.3","Single Cell Type RNA - Bipolar cells [nTPM]":"54.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"63.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"80.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"46.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"52.6","Single Cell Type RNA - dendritic cells [nTPM]":"66.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"56.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"44.0","Single Cell Type RNA - Early spermatids [nTPM]":"32.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"139.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"98.0","Single Cell Type RNA - Endothelial cells [nTPM]":"61.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"104.7","Single Cell Type RNA - Erythroid cells [nTPM]":"34.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"87.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"42.4","Single Cell Type RNA - Fibroblasts [nTPM]":"56.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"55.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"154.6","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"105.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.2","Single Cell Type RNA - Hepatocytes [nTPM]":"61.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.0","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"87.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"65.6","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"78.3","Single Cell Type RNA - Langerhans cells [nTPM]":"49.8","Single Cell Type RNA - Late spermatids [nTPM]":"21.5","Single Cell Type RNA - Leydig cells [nTPM]":"72.1","Single Cell Type RNA - Macrophages [nTPM]":"50.4","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"102.1","Single Cell Type RNA - monocytes [nTPM]":"56.6","Single Cell Type RNA - Muller glia cells [nTPM]":"41.6","Single Cell Type RNA - NK-cells [nTPM]":"69.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"111.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"101.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.1","Single Cell Type RNA - Paneth cells [nTPM]":"45.0","Single Cell Type RNA - Peritubular cells [nTPM]":"80.5","Single Cell Type RNA - Plasma cells [nTPM]":"41.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"84.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"49.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"81.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.5","Single Cell Type RNA - Spermatocytes [nTPM]":"36.4","Single Cell Type RNA - Spermatogonia [nTPM]":"24.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"62.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"93.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"78.0","Single Cell Type RNA - T-cells [nTPM]":"50.5","Single Cell Type RNA - Theca cells [nTPM]":"63.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"75.8","Single Cell Type RNA - Urothelial cells [nTPM]":"95.5"},{"Gene":"PXMP2","Gene synonym":["MPV17L3","PMP22"],"Ensembl":"ENSG00000176894","Gene description":"Peroxisomal membrane protein 2","Uniprot":["Q9NR77"],"Chromosome":"12","Position":"132687587-132704985","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"312.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"187.3","Hepatocytes":"577.4","Proximal enterocytes":"333.3","Proximal tubular cells":"303.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"43.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.84e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.75e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.8","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"23.7","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"24.3","Tissue RNA - bone marrow [nTPM]":"23.4","Tissue RNA - breast [nTPM]":"18.7","Tissue RNA - cerebellum [nTPM]":"24.5","Tissue RNA - cerebral cortex [nTPM]":"29.8","Tissue RNA - cervix [nTPM]":"14.3","Tissue RNA - choroid plexus [nTPM]":"37.7","Tissue RNA - colon [nTPM]":"49.5","Tissue RNA - duodenum [nTPM]":"52.1","Tissue RNA - endometrium 1 [nTPM]":"14.9","Tissue RNA - epididymis [nTPM]":"22.3","Tissue RNA - esophagus [nTPM]":"16.2","Tissue RNA - fallopian tube [nTPM]":"18.7","Tissue RNA - gallbladder [nTPM]":"15.4","Tissue RNA - heart muscle [nTPM]":"62.9","Tissue RNA - hippocampal formation [nTPM]":"28.5","Tissue RNA - hypothalamus [nTPM]":"24.1","Tissue RNA - kidney [nTPM]":"58.2","Tissue RNA - liver [nTPM]":"312.0","Tissue RNA - lung [nTPM]":"12.9","Tissue RNA - lymph node [nTPM]":"11.5","Tissue RNA - medulla oblongata [nTPM]":"24.1","Tissue RNA - midbrain [nTPM]":"24.2","Tissue RNA - ovary [nTPM]":"23.0","Tissue RNA - pancreas [nTPM]":"42.5","Tissue RNA - parathyroid gland [nTPM]":"14.5","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"8.1","Tissue RNA - pons [nTPM]":"22.9","Tissue RNA - prostate [nTPM]":"19.8","Tissue RNA - rectum [nTPM]":"39.2","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"18.6","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"42.3","Tissue RNA - skin 1 [nTPM]":"16.8","Tissue RNA - small intestine [nTPM]":"55.1","Tissue RNA - smooth muscle [nTPM]":"9.5","Tissue RNA - spinal cord [nTPM]":"23.0","Tissue RNA - spleen [nTPM]":"13.1","Tissue RNA - stomach 1 [nTPM]":"98.2","Tissue RNA - testis [nTPM]":"9.1","Tissue RNA - thalamus [nTPM]":"24.9","Tissue RNA - thymus [nTPM]":"25.9","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"30.5","Tissue RNA - tonsil [nTPM]":"10.7","Tissue RNA - urinary bladder [nTPM]":"15.9","Tissue RNA - vagina [nTPM]":"12.8","Tissue RNA - white matter [nTPM]":"23.5","Cell RNA - A-431 [nTPM]":"60.5","Cell RNA - A549 [nTPM]":"24.8","Cell RNA - AF22 [nTPM]":"36.6","Cell RNA - AN3-CA [nTPM]":"34.1","Cell RNA - ASC diff [nTPM]":"21.5","Cell RNA - ASC TERT1 [nTPM]":"16.6","Cell RNA - BEWO [nTPM]":"21.4","Cell RNA - BJ [nTPM]":"21.0","Cell RNA - BJ hTERT+ [nTPM]":"19.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.6","Cell RNA - CACO-2 [nTPM]":"30.3","Cell RNA - CAPAN-2 [nTPM]":"22.4","Cell RNA - Daudi [nTPM]":"37.2","Cell RNA - EFO-21 [nTPM]":"24.9","Cell RNA - fHDF\/TERT166 [nTPM]":"30.0","Cell RNA - GAMG [nTPM]":"15.7","Cell RNA - HaCaT [nTPM]":"42.0","Cell RNA - HAP1 [nTPM]":"49.1","Cell RNA - HBEC3-KT [nTPM]":"26.6","Cell RNA - HBF TERT88 [nTPM]":"24.3","Cell RNA - HDLM-2 [nTPM]":"21.3","Cell RNA - HEK 293 [nTPM]":"77.8","Cell RNA - HEL [nTPM]":"33.2","Cell RNA - HeLa [nTPM]":"43.9","Cell RNA - Hep G2 [nTPM]":"33.8","Cell RNA - HHSteC [nTPM]":"41.7","Cell RNA - HL-60 [nTPM]":"24.8","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"21.7","Cell RNA - hTCEpi [nTPM]":"21.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.6","Cell RNA - hTERT-HME1 [nTPM]":"14.7","Cell RNA - hTERT-RPE1 [nTPM]":"31.2","Cell RNA - HUVEC TERT2 [nTPM]":"12.1","Cell RNA - JURKAT [nTPM]":"56.2","Cell RNA - K-562 [nTPM]":"58.2","Cell RNA - Karpas-707 [nTPM]":"28.4","Cell RNA - LHCN-M2 [nTPM]":"23.8","Cell RNA - MCF7 [nTPM]":"54.2","Cell RNA - MOLT-4 [nTPM]":"78.9","Cell RNA - NB-4 [nTPM]":"39.2","Cell RNA - NTERA-2 [nTPM]":"35.7","Cell RNA - OE19 [nTPM]":"70.0","Cell RNA - PC-3 [nTPM]":"33.9","Cell RNA - REH [nTPM]":"80.1","Cell RNA - RH-30 [nTPM]":"39.2","Cell RNA - RPMI-8226 [nTPM]":"30.6","Cell RNA - RPTEC TERT1 [nTPM]":"32.9","Cell RNA - RT4 [nTPM]":"25.2","Cell RNA - SCLC-21H [nTPM]":"69.0","Cell RNA - SH-SY5Y [nTPM]":"22.5","Cell RNA - SiHa [nTPM]":"45.6","Cell RNA - SK-BR-3 [nTPM]":"23.6","Cell RNA - SK-MEL-30 [nTPM]":"29.6","Cell RNA - SuSa [nTPM]":"28.1","Cell RNA - T-47d [nTPM]":"63.2","Cell RNA - THP-1 [nTPM]":"56.0","Cell RNA - TIME [nTPM]":"14.3","Cell RNA - U-138 MG [nTPM]":"21.9","Cell RNA - U-2 OS [nTPM]":"51.1","Cell RNA - U-2197 [nTPM]":"19.1","Cell RNA - U-251 MG [nTPM]":"35.6","Cell RNA - U-266\/70 [nTPM]":"25.7","Cell RNA - U-266\/84 [nTPM]":"26.7","Cell RNA - U-698 [nTPM]":"60.6","Cell RNA - U-87 MG [nTPM]":"24.6","Cell RNA - U-937 [nTPM]":"34.9","Cell RNA - WM-115 [nTPM]":"17.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"6.3","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"23.7","Brain RNA - basal ganglia [nTPM]":"24.3","Brain RNA - cerebellum [nTPM]":"24.5","Brain RNA - cerebral cortex [nTPM]":"29.8","Brain RNA - hippocampal formation [nTPM]":"28.5","Brain RNA - hypothalamus [nTPM]":"24.1","Brain RNA - medulla oblongata [nTPM]":"24.1","Brain RNA - midbrain [nTPM]":"24.2","Brain RNA - pons [nTPM]":"22.9","Brain RNA - spinal cord [nTPM]":"23.0","Brain RNA - thalamus [nTPM]":"24.9","Brain RNA - white matter [nTPM]":"23.5","Single Cell Type RNA - Adipocytes [nTPM]":"10.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.2","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"6.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"50.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"51.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"138.7","Single Cell Type RNA - Club cells [nTPM]":"6.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"60.1","Single Cell Type RNA - dendritic cells [nTPM]":"7.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"187.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"166.3","Single Cell Type RNA - Ductal cells [nTPM]":"16.5","Single Cell Type RNA - Early spermatids [nTPM]":"18.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.9","Single Cell Type RNA - Endothelial cells [nTPM]":"14.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.7","Single Cell Type RNA - Erythroid cells [nTPM]":"55.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"65.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.4","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"32.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.8","Single Cell Type RNA - Hepatocytes [nTPM]":"577.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"85.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"19.2","Single Cell Type RNA - Langerhans cells [nTPM]":"9.4","Single Cell Type RNA - Late spermatids [nTPM]":"38.8","Single Cell Type RNA - Leydig cells [nTPM]":"31.1","Single Cell Type RNA - Macrophages [nTPM]":"8.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"45.5","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.2","Single Cell Type RNA - Paneth cells [nTPM]":"143.4","Single Cell Type RNA - Peritubular cells [nTPM]":"35.0","Single Cell Type RNA - Plasma cells [nTPM]":"20.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"333.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"303.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.8","Single Cell Type RNA - Spermatocytes [nTPM]":"44.9","Single Cell Type RNA - Spermatogonia [nTPM]":"30.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.5","Single Cell Type RNA - T-cells [nTPM]":"8.1","Single Cell Type RNA - Theca cells [nTPM]":"12.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"158.6","Single Cell Type RNA - Urothelial cells [nTPM]":"23.2"},{"Gene":"RAB28","Gene synonym":[],"Ensembl":"ENSG00000157869","Gene description":"RAB28, member RAS oncogene family","Uniprot":["P51157"],"Chromosome":"4","Position":"13361354-13484365","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cone-rod dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"119.9","Inhibitory neurons":"140.4","Spermatocytes":"123.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044575"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044575":"AB_10959460"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.61e-4"},"Tissue RNA - adipose tissue [nTPM]":"17.1","Tissue RNA - adrenal gland [nTPM]":"18.9","Tissue RNA - amygdala [nTPM]":"22.9","Tissue RNA - appendix [nTPM]":"12.8","Tissue RNA - basal ganglia [nTPM]":"25.2","Tissue RNA - bone marrow [nTPM]":"19.3","Tissue RNA - breast [nTPM]":"20.3","Tissue RNA - cerebellum [nTPM]":"39.5","Tissue RNA - cerebral cortex [nTPM]":"29.2","Tissue RNA - cervix [nTPM]":"15.3","Tissue RNA - choroid plexus [nTPM]":"24.9","Tissue RNA - colon [nTPM]":"16.2","Tissue RNA - duodenum [nTPM]":"11.0","Tissue RNA - endometrium 1 [nTPM]":"22.5","Tissue RNA - epididymis [nTPM]":"18.8","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"21.9","Tissue RNA - gallbladder [nTPM]":"15.5","Tissue RNA - heart muscle [nTPM]":"30.4","Tissue RNA - hippocampal formation [nTPM]":"23.7","Tissue RNA - hypothalamus [nTPM]":"29.5","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"11.9","Tissue RNA - lung [nTPM]":"16.1","Tissue RNA - lymph node [nTPM]":"18.3","Tissue RNA - medulla oblongata [nTPM]":"22.3","Tissue RNA - midbrain [nTPM]":"26.7","Tissue RNA - ovary [nTPM]":"22.4","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"23.9","Tissue RNA - pituitary gland [nTPM]":"19.3","Tissue RNA - placenta [nTPM]":"19.5","Tissue RNA - pons [nTPM]":"24.7","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"18.1","Tissue RNA - retina [nTPM]":"55.4","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"16.0","Tissue RNA - skeletal muscle [nTPM]":"7.2","Tissue RNA - skin 1 [nTPM]":"19.9","Tissue RNA - small intestine [nTPM]":"11.3","Tissue RNA - smooth muscle [nTPM]":"17.3","Tissue RNA - spinal cord [nTPM]":"24.3","Tissue RNA - spleen [nTPM]":"17.2","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"37.7","Tissue RNA - thalamus [nTPM]":"29.6","Tissue RNA - thymus [nTPM]":"18.4","Tissue RNA - thyroid gland [nTPM]":"19.5","Tissue RNA - tongue [nTPM]":"13.3","Tissue RNA - tonsil [nTPM]":"16.7","Tissue RNA - urinary bladder [nTPM]":"13.2","Tissue RNA - vagina [nTPM]":"13.3","Tissue RNA - white matter [nTPM]":"28.9","Cell RNA - A-431 [nTPM]":"22.0","Cell RNA - A549 [nTPM]":"11.4","Cell RNA - AF22 [nTPM]":"36.3","Cell RNA - AN3-CA [nTPM]":"18.6","Cell RNA - ASC diff [nTPM]":"18.7","Cell RNA - ASC TERT1 [nTPM]":"34.8","Cell RNA - BEWO [nTPM]":"19.0","Cell RNA - BJ [nTPM]":"19.7","Cell RNA - BJ hTERT+ [nTPM]":"22.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.9","Cell RNA - CACO-2 [nTPM]":"11.3","Cell RNA - CAPAN-2 [nTPM]":"22.7","Cell RNA - Daudi [nTPM]":"26.0","Cell RNA - EFO-21 [nTPM]":"12.5","Cell RNA - fHDF\/TERT166 [nTPM]":"19.3","Cell RNA - GAMG [nTPM]":"46.0","Cell RNA - HaCaT [nTPM]":"11.1","Cell RNA - HAP1 [nTPM]":"31.4","Cell RNA - HBEC3-KT [nTPM]":"17.6","Cell RNA - HBF TERT88 [nTPM]":"39.3","Cell RNA - HDLM-2 [nTPM]":"16.7","Cell RNA - HEK 293 [nTPM]":"15.7","Cell RNA - HEL [nTPM]":"18.6","Cell RNA - HeLa [nTPM]":"20.1","Cell RNA - Hep G2 [nTPM]":"10.8","Cell RNA - HHSteC [nTPM]":"18.3","Cell RNA - HL-60 [nTPM]":"21.2","Cell RNA - HMC-1 [nTPM]":"10.9","Cell RNA - HSkMC [nTPM]":"16.0","Cell RNA - hTCEpi [nTPM]":"23.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.8","Cell RNA - hTERT-HME1 [nTPM]":"18.7","Cell RNA - hTERT-RPE1 [nTPM]":"26.5","Cell RNA - HUVEC TERT2 [nTPM]":"23.9","Cell RNA - JURKAT [nTPM]":"32.9","Cell RNA - K-562 [nTPM]":"37.0","Cell RNA - Karpas-707 [nTPM]":"97.1","Cell RNA - LHCN-M2 [nTPM]":"30.4","Cell RNA - MCF7 [nTPM]":"8.8","Cell RNA - MOLT-4 [nTPM]":"45.3","Cell RNA - NB-4 [nTPM]":"52.7","Cell RNA - NTERA-2 [nTPM]":"50.7","Cell RNA - OE19 [nTPM]":"16.4","Cell RNA - PC-3 [nTPM]":"19.9","Cell RNA - REH [nTPM]":"28.6","Cell RNA - RH-30 [nTPM]":"22.8","Cell RNA - RPMI-8226 [nTPM]":"21.5","Cell RNA - RPTEC TERT1 [nTPM]":"18.7","Cell RNA - RT4 [nTPM]":"11.9","Cell RNA - SCLC-21H [nTPM]":"28.7","Cell RNA - SH-SY5Y [nTPM]":"17.3","Cell RNA - SiHa [nTPM]":"17.0","Cell RNA - SK-BR-3 [nTPM]":"12.2","Cell RNA - SK-MEL-30 [nTPM]":"28.1","Cell RNA - SuSa [nTPM]":"28.2","Cell RNA - T-47d [nTPM]":"13.7","Cell RNA - THP-1 [nTPM]":"23.8","Cell RNA - TIME [nTPM]":"16.5","Cell RNA - U-138 MG [nTPM]":"28.8","Cell RNA - U-2 OS [nTPM]":"12.6","Cell RNA - U-2197 [nTPM]":"23.8","Cell RNA - U-251 MG [nTPM]":"30.7","Cell RNA - U-266\/70 [nTPM]":"24.0","Cell RNA - U-266\/84 [nTPM]":"18.0","Cell RNA - U-698 [nTPM]":"34.6","Cell RNA - U-87 MG [nTPM]":"25.7","Cell RNA - U-937 [nTPM]":"38.3","Cell RNA - WM-115 [nTPM]":"38.6","Blood RNA - basophil [nTPM]":"21.0","Blood RNA - classical monocyte [nTPM]":"16.2","Blood RNA - eosinophil [nTPM]":"26.1","Blood RNA - gdT-cell [nTPM]":"16.5","Blood RNA - intermediate monocyte [nTPM]":"15.6","Blood RNA - MAIT T-cell [nTPM]":"17.0","Blood RNA - memory B-cell [nTPM]":"18.4","Blood RNA - memory CD4 T-cell [nTPM]":"15.3","Blood RNA - memory CD8 T-cell [nTPM]":"16.2","Blood RNA - myeloid DC [nTPM]":"16.8","Blood RNA - naive B-cell [nTPM]":"17.9","Blood RNA - naive CD4 T-cell [nTPM]":"20.3","Blood RNA - naive CD8 T-cell [nTPM]":"16.5","Blood RNA - neutrophil [nTPM]":"15.1","Blood RNA - NK-cell [nTPM]":"20.6","Blood RNA - non-classical monocyte [nTPM]":"14.4","Blood RNA - plasmacytoid DC [nTPM]":"12.9","Blood RNA - T-reg [nTPM]":"17.2","Blood RNA - total PBMC [nTPM]":"10.6","Brain RNA - amygdala [nTPM]":"22.9","Brain RNA - basal ganglia [nTPM]":"25.2","Brain RNA - cerebellum [nTPM]":"39.5","Brain RNA - cerebral cortex [nTPM]":"29.2","Brain RNA - hippocampal formation [nTPM]":"23.7","Brain RNA - hypothalamus [nTPM]":"29.5","Brain RNA - medulla oblongata [nTPM]":"22.3","Brain RNA - midbrain [nTPM]":"26.7","Brain RNA - pons [nTPM]":"24.7","Brain RNA - spinal cord [nTPM]":"24.3","Brain RNA - thalamus [nTPM]":"29.6","Brain RNA - white matter [nTPM]":"28.9","Single Cell Type RNA - Adipocytes [nTPM]":"17.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"81.0","Single Cell Type RNA - B-cells [nTPM]":"22.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"31.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"16.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.3","Single Cell Type RNA - dendritic cells [nTPM]":"15.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"12.9","Single Cell Type RNA - Early spermatids [nTPM]":"19.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.7","Single Cell Type RNA - Endothelial cells [nTPM]":"18.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"119.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.7","Single Cell Type RNA - Fibroblasts [nTPM]":"27.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.2","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"12.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"6.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.0","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"140.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"15.1","Single Cell Type RNA - Langerhans cells [nTPM]":"18.2","Single Cell Type RNA - Late spermatids [nTPM]":"20.6","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"16.7","Single Cell Type RNA - Muller glia cells [nTPM]":"44.5","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"97.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"79.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.8","Single Cell Type RNA - Peritubular cells [nTPM]":"24.0","Single Cell Type RNA - Plasma cells [nTPM]":"19.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.1","Single Cell Type RNA - Spermatocytes [nTPM]":"123.9","Single Cell Type RNA - Spermatogonia [nTPM]":"63.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - T-cells [nTPM]":"21.3","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.6","Single Cell Type RNA - Urothelial cells [nTPM]":"19.0"},{"Gene":"RAB7A","Gene synonym":["CMT2B","RAB7"],"Ensembl":"ENSG00000075785","Gene description":"RAB7A, member RAS oncogene family","Uniprot":["P51149"],"Chromosome":"3","Position":"128693669-128825942","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","Host-virus interaction","Lipid degradation","Lipid metabolism","Protein transport","Transport"],"Molecular function":["Hydrolase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006964","CAB037131"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Lysosomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5700000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Lysosomes"],"Subcellular additional location":null,"Antibody RRID":{"CAB037131":"AB_477460","HPA006964":"AB_1856015"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.89e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Tissue RNA - adipose tissue [nTPM]":"170.6","Tissue RNA - adrenal gland [nTPM]":"157.1","Tissue RNA - amygdala [nTPM]":"120.1","Tissue RNA - appendix [nTPM]":"101.4","Tissue RNA - basal ganglia [nTPM]":"132.2","Tissue RNA - bone marrow [nTPM]":"99.9","Tissue RNA - breast [nTPM]":"149.5","Tissue RNA - cerebellum [nTPM]":"133.4","Tissue RNA - cerebral cortex [nTPM]":"159.4","Tissue RNA - cervix [nTPM]":"138.3","Tissue RNA - choroid plexus [nTPM]":"123.7","Tissue RNA - colon [nTPM]":"128.9","Tissue RNA - duodenum [nTPM]":"108.3","Tissue RNA - endometrium 1 [nTPM]":"137.4","Tissue RNA - epididymis [nTPM]":"143.0","Tissue RNA - esophagus [nTPM]":"188.2","Tissue RNA - fallopian tube [nTPM]":"110.1","Tissue RNA - gallbladder [nTPM]":"109.7","Tissue RNA - heart muscle [nTPM]":"186.8","Tissue RNA - hippocampal formation [nTPM]":"128.9","Tissue RNA - hypothalamus [nTPM]":"138.4","Tissue RNA - kidney [nTPM]":"131.8","Tissue RNA - liver [nTPM]":"145.2","Tissue RNA - lung [nTPM]":"152.9","Tissue RNA - lymph node [nTPM]":"108.8","Tissue RNA - medulla oblongata [nTPM]":"138.8","Tissue RNA - midbrain [nTPM]":"142.0","Tissue RNA - ovary [nTPM]":"122.7","Tissue RNA - pancreas [nTPM]":"88.6","Tissue RNA - parathyroid gland [nTPM]":"155.9","Tissue RNA - pituitary gland [nTPM]":"101.5","Tissue RNA - placenta [nTPM]":"117.5","Tissue RNA - pons [nTPM]":"139.4","Tissue RNA - prostate [nTPM]":"101.3","Tissue RNA - rectum [nTPM]":"126.0","Tissue RNA - retina [nTPM]":"103.8","Tissue RNA - salivary gland [nTPM]":"133.3","Tissue RNA - seminal vesicle [nTPM]":"63.9","Tissue RNA - skeletal muscle [nTPM]":"332.4","Tissue RNA - skin 1 [nTPM]":"164.9","Tissue RNA - small intestine [nTPM]":"116.8","Tissue RNA - smooth muscle [nTPM]":"124.0","Tissue RNA - spinal cord [nTPM]":"135.9","Tissue RNA - spleen [nTPM]":"123.0","Tissue RNA - stomach 1 [nTPM]":"114.9","Tissue RNA - testis [nTPM]":"61.5","Tissue RNA - thalamus [nTPM]":"140.3","Tissue RNA - thymus [nTPM]":"124.6","Tissue RNA - thyroid gland [nTPM]":"122.5","Tissue RNA - tongue [nTPM]":"249.7","Tissue RNA - tonsil [nTPM]":"136.6","Tissue RNA - urinary bladder [nTPM]":"144.4","Tissue RNA - vagina [nTPM]":"143.4","Tissue RNA - white matter [nTPM]":"159.0","Cell RNA - A-431 [nTPM]":"280.2","Cell RNA - A549 [nTPM]":"95.5","Cell RNA - AF22 [nTPM]":"146.0","Cell RNA - AN3-CA [nTPM]":"78.3","Cell RNA - ASC diff [nTPM]":"300.6","Cell RNA - ASC TERT1 [nTPM]":"94.0","Cell RNA - BEWO [nTPM]":"126.0","Cell RNA - BJ [nTPM]":"252.8","Cell RNA - BJ hTERT+ [nTPM]":"183.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"164.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"158.8","Cell RNA - CACO-2 [nTPM]":"170.1","Cell RNA - CAPAN-2 [nTPM]":"179.2","Cell RNA - Daudi [nTPM]":"134.2","Cell RNA - EFO-21 [nTPM]":"163.2","Cell RNA - fHDF\/TERT166 [nTPM]":"236.2","Cell RNA - GAMG [nTPM]":"289.9","Cell RNA - HaCaT [nTPM]":"163.4","Cell RNA - HAP1 [nTPM]":"175.2","Cell RNA - HBEC3-KT [nTPM]":"248.6","Cell RNA - HBF TERT88 [nTPM]":"99.2","Cell RNA - HDLM-2 [nTPM]":"149.4","Cell RNA - HEK 293 [nTPM]":"111.7","Cell RNA - HEL [nTPM]":"294.3","Cell RNA - HeLa [nTPM]":"83.6","Cell RNA - Hep G2 [nTPM]":"165.8","Cell RNA - HHSteC [nTPM]":"303.0","Cell RNA - HL-60 [nTPM]":"269.4","Cell RNA - HMC-1 [nTPM]":"182.5","Cell RNA - HSkMC [nTPM]":"243.7","Cell RNA - hTCEpi [nTPM]":"104.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"176.7","Cell RNA - hTERT-HME1 [nTPM]":"204.4","Cell RNA - hTERT-RPE1 [nTPM]":"220.7","Cell RNA - HUVEC TERT2 [nTPM]":"89.2","Cell RNA - JURKAT [nTPM]":"114.4","Cell RNA - K-562 [nTPM]":"143.4","Cell RNA - Karpas-707 [nTPM]":"148.0","Cell RNA - LHCN-M2 [nTPM]":"108.1","Cell RNA - MCF7 [nTPM]":"213.1","Cell RNA - MOLT-4 [nTPM]":"176.8","Cell RNA - NB-4 [nTPM]":"294.6","Cell RNA - NTERA-2 [nTPM]":"121.4","Cell RNA - OE19 [nTPM]":"294.8","Cell RNA - PC-3 [nTPM]":"144.8","Cell RNA - REH [nTPM]":"140.2","Cell RNA - RH-30 [nTPM]":"130.7","Cell RNA - RPMI-8226 [nTPM]":"170.4","Cell RNA - RPTEC TERT1 [nTPM]":"85.7","Cell RNA - RT4 [nTPM]":"205.4","Cell RNA - SCLC-21H [nTPM]":"105.8","Cell RNA - SH-SY5Y [nTPM]":"138.5","Cell RNA - SiHa [nTPM]":"142.1","Cell RNA - SK-BR-3 [nTPM]":"194.7","Cell RNA - SK-MEL-30 [nTPM]":"405.4","Cell RNA - SuSa [nTPM]":"174.9","Cell RNA - T-47d [nTPM]":"180.3","Cell RNA - THP-1 [nTPM]":"254.8","Cell RNA - TIME [nTPM]":"202.9","Cell RNA - U-138 MG [nTPM]":"192.7","Cell RNA - U-2 OS [nTPM]":"98.0","Cell RNA - U-2197 [nTPM]":"325.7","Cell RNA - U-251 MG [nTPM]":"125.9","Cell RNA - U-266\/70 [nTPM]":"184.4","Cell RNA - U-266\/84 [nTPM]":"187.0","Cell RNA - U-698 [nTPM]":"192.0","Cell RNA - U-87 MG [nTPM]":"312.7","Cell RNA - U-937 [nTPM]":"212.1","Cell RNA - WM-115 [nTPM]":"235.5","Blood RNA - basophil [nTPM]":"194.9","Blood RNA - classical monocyte [nTPM]":"176.8","Blood RNA - eosinophil [nTPM]":"213.6","Blood RNA - gdT-cell [nTPM]":"92.1","Blood RNA - intermediate monocyte [nTPM]":"192.3","Blood RNA - MAIT T-cell [nTPM]":"92.3","Blood RNA - memory B-cell [nTPM]":"93.2","Blood RNA - memory CD4 T-cell [nTPM]":"97.4","Blood RNA - memory CD8 T-cell [nTPM]":"94.5","Blood RNA - myeloid DC [nTPM]":"200.0","Blood RNA - naive B-cell [nTPM]":"85.8","Blood RNA - naive CD4 T-cell [nTPM]":"94.8","Blood RNA - naive CD8 T-cell [nTPM]":"93.6","Blood RNA - neutrophil [nTPM]":"374.2","Blood RNA - NK-cell [nTPM]":"128.8","Blood RNA - non-classical monocyte [nTPM]":"204.0","Blood RNA - plasmacytoid DC [nTPM]":"81.8","Blood RNA - T-reg [nTPM]":"120.7","Blood RNA - total PBMC [nTPM]":"201.3","Brain RNA - amygdala [nTPM]":"120.1","Brain RNA - basal ganglia [nTPM]":"132.2","Brain RNA - cerebellum [nTPM]":"133.4","Brain RNA - cerebral cortex [nTPM]":"159.4","Brain RNA - hippocampal formation [nTPM]":"128.9","Brain RNA - hypothalamus [nTPM]":"138.4","Brain RNA - medulla oblongata [nTPM]":"138.8","Brain RNA - midbrain [nTPM]":"142.0","Brain RNA - pons [nTPM]":"139.4","Brain RNA - spinal cord [nTPM]":"135.9","Brain RNA - thalamus [nTPM]":"140.3","Brain RNA - white matter [nTPM]":"159.0","Single Cell Type RNA - Adipocytes [nTPM]":"154.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"81.8","Single Cell Type RNA - Astrocytes [nTPM]":"66.9","Single Cell Type RNA - B-cells [nTPM]":"109.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"296.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"331.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"218.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"104.7","Single Cell Type RNA - Bipolar cells [nTPM]":"66.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"112.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"73.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"110.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"90.1","Single Cell Type RNA - Club cells [nTPM]":"129.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"132.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"230.0","Single Cell Type RNA - dendritic cells [nTPM]":"92.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"222.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"240.7","Single Cell Type RNA - Ductal cells [nTPM]":"259.6","Single Cell Type RNA - Early spermatids [nTPM]":"11.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"90.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"90.8","Single Cell Type RNA - Endothelial cells [nTPM]":"165.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"96.9","Single Cell Type RNA - Erythroid cells [nTPM]":"111.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"83.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"198.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"283.4","Single Cell Type RNA - Fibroblasts [nTPM]":"172.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"79.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"142.4","Single Cell Type RNA - granulocytes [nTPM]":"146.2","Single Cell Type RNA - Granulosa cells [nTPM]":"46.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"142.8","Single Cell Type RNA - Hepatocytes [nTPM]":"127.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"403.9","Single Cell Type RNA - Horizontal cells [nTPM]":"74.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"122.8","Single Cell Type RNA - Ionocytes [nTPM]":"219.7","Single Cell Type RNA - Kupffer cells [nTPM]":"208.6","Single Cell Type RNA - Langerhans cells [nTPM]":"379.9","Single Cell Type RNA - Late spermatids [nTPM]":"19.6","Single Cell Type RNA - Leydig cells [nTPM]":"133.6","Single Cell Type RNA - Macrophages [nTPM]":"242.8","Single Cell Type RNA - Melanocytes [nTPM]":"339.7","Single Cell Type RNA - Microglial cells [nTPM]":"99.3","Single Cell Type RNA - monocytes [nTPM]":"220.9","Single Cell Type RNA - Muller glia cells [nTPM]":"154.6","Single Cell Type RNA - NK-cells [nTPM]":"121.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"80.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"111.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"303.7","Single Cell Type RNA - Paneth cells [nTPM]":"185.0","Single Cell Type RNA - Peritubular cells [nTPM]":"157.2","Single Cell Type RNA - Plasma cells [nTPM]":"79.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"279.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"172.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"332.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"118.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.6","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"107.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"160.5","Single Cell Type RNA - Spermatocytes [nTPM]":"116.4","Single Cell Type RNA - Spermatogonia [nTPM]":"100.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"122.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"308.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"497.9","Single Cell Type RNA - T-cells [nTPM]":"107.7","Single Cell Type RNA - Theca cells [nTPM]":"109.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"103.5","Single Cell Type RNA - Urothelial cells [nTPM]":"324.6"},{"Gene":"RAD51","Gene synonym":["BRCC5","FANCR","HsRad51","HsT16930","RAD51A","RECA"],"Ensembl":"ENSG00000051180","Gene description":"RAD51 recombinase","Uniprot":["Q06609"],"Chromosome":"15","Position":"40694774-40732340","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA recombination","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"15.7","testis":"24.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"35.3","Extravillous trophoblasts":"67.2","Spermatocytes":"53.6","Spermatogonia":"24.8","Syncytiotrophoblasts":"25.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"19.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010381","HPA039310"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli rim","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoli rim"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB010381":"AB_2253533","HPA039310":"AB_2676434"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.94e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.33e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"10.5","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"8.3","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"4.2","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"11.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"6.8","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"9.1","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"3.1","Tissue RNA - small intestine [nTPM]":"4.1","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"1.8","Tissue RNA - testis [nTPM]":"24.3","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"15.7","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"33.8","Cell RNA - A549 [nTPM]":"16.1","Cell RNA - AF22 [nTPM]":"33.4","Cell RNA - AN3-CA [nTPM]":"16.3","Cell RNA - ASC diff [nTPM]":"4.4","Cell RNA - ASC TERT1 [nTPM]":"7.8","Cell RNA - BEWO [nTPM]":"31.1","Cell RNA - BJ [nTPM]":"54.9","Cell RNA - BJ hTERT+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.8","Cell RNA - CACO-2 [nTPM]":"35.4","Cell RNA - CAPAN-2 [nTPM]":"22.1","Cell RNA - Daudi [nTPM]":"20.4","Cell RNA - EFO-21 [nTPM]":"26.8","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"18.9","Cell RNA - HaCaT [nTPM]":"67.7","Cell RNA - HAP1 [nTPM]":"56.6","Cell RNA - HBEC3-KT [nTPM]":"22.1","Cell RNA - HBF TERT88 [nTPM]":"42.3","Cell RNA - HDLM-2 [nTPM]":"39.0","Cell RNA - HEK 293 [nTPM]":"22.2","Cell RNA - HEL [nTPM]":"47.7","Cell RNA - HeLa [nTPM]":"28.2","Cell RNA - Hep G2 [nTPM]":"30.4","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"37.9","Cell RNA - HMC-1 [nTPM]":"28.5","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"2.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.0","Cell RNA - hTERT-HME1 [nTPM]":"13.5","Cell RNA - hTERT-RPE1 [nTPM]":"6.4","Cell RNA - HUVEC TERT2 [nTPM]":"22.5","Cell RNA - JURKAT [nTPM]":"48.5","Cell RNA - K-562 [nTPM]":"59.6","Cell RNA - Karpas-707 [nTPM]":"55.8","Cell RNA - LHCN-M2 [nTPM]":"36.6","Cell RNA - MCF7 [nTPM]":"28.5","Cell RNA - MOLT-4 [nTPM]":"54.4","Cell RNA - NB-4 [nTPM]":"43.6","Cell RNA - NTERA-2 [nTPM]":"35.2","Cell RNA - OE19 [nTPM]":"69.2","Cell RNA - PC-3 [nTPM]":"19.0","Cell RNA - REH [nTPM]":"61.0","Cell RNA - RH-30 [nTPM]":"49.0","Cell RNA - RPMI-8226 [nTPM]":"30.7","Cell RNA - RPTEC TERT1 [nTPM]":"15.4","Cell RNA - RT4 [nTPM]":"45.3","Cell RNA - SCLC-21H [nTPM]":"15.4","Cell RNA - SH-SY5Y [nTPM]":"27.0","Cell RNA - SiHa [nTPM]":"23.6","Cell RNA - SK-BR-3 [nTPM]":"41.4","Cell RNA - SK-MEL-30 [nTPM]":"8.5","Cell RNA - SuSa [nTPM]":"39.2","Cell RNA - T-47d [nTPM]":"27.0","Cell RNA - THP-1 [nTPM]":"39.4","Cell RNA - TIME [nTPM]":"9.9","Cell RNA - U-138 MG [nTPM]":"32.8","Cell RNA - U-2 OS [nTPM]":"22.2","Cell RNA - U-2197 [nTPM]":"48.7","Cell RNA - U-251 MG [nTPM]":"27.2","Cell RNA - U-266\/70 [nTPM]":"12.0","Cell RNA - U-266\/84 [nTPM]":"65.1","Cell RNA - U-698 [nTPM]":"59.8","Cell RNA - U-87 MG [nTPM]":"16.3","Cell RNA - U-937 [nTPM]":"78.0","Cell RNA - WM-115 [nTPM]":"33.5","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.3","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"67.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"8.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"53.6","Single Cell Type RNA - Spermatogonia [nTPM]":"24.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"RAPGEF2","Gene synonym":["DKFZP586O1422","KIAA0313","PDZ-GEF1","PDZGEF1","RA-GEF"],"Ensembl":"ENSG00000109756","Gene description":"Rap guanine nucleotide exchange factor 2","Uniprot":["Q9Y4G8"],"Chromosome":"4","Position":"159103013-159360174","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","GTPase activation","Guanine-nucleotide releasing factor"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"456.2","Inhibitory neurons":"264.1","Microglial cells":"238.9","Oligodendrocyte precursor cells":"199.0","Oligodendrocytes":"236.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"5.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"5.9","NK-cells":"3.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"104.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068798"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA068798":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.7","Tissue RNA - adrenal gland [nTPM]":"9.4","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"13.4","Tissue RNA - basal ganglia [nTPM]":"19.8","Tissue RNA - bone marrow [nTPM]":"87.5","Tissue RNA - breast [nTPM]":"24.1","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"32.1","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"21.8","Tissue RNA - duodenum [nTPM]":"15.9","Tissue RNA - endometrium 1 [nTPM]":"16.1","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"13.8","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"20.1","Tissue RNA - heart muscle [nTPM]":"23.2","Tissue RNA - hippocampal formation [nTPM]":"27.4","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"22.7","Tissue RNA - liver [nTPM]":"30.5","Tissue RNA - lung [nTPM]":"26.6","Tissue RNA - lymph node [nTPM]":"11.9","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"19.5","Tissue RNA - parathyroid gland [nTPM]":"23.5","Tissue RNA - pituitary gland [nTPM]":"15.3","Tissue RNA - placenta [nTPM]":"38.5","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"12.2","Tissue RNA - rectum [nTPM]":"20.8","Tissue RNA - retina [nTPM]":"35.1","Tissue RNA - salivary gland [nTPM]":"25.3","Tissue RNA - seminal vesicle [nTPM]":"12.6","Tissue RNA - skeletal muscle [nTPM]":"21.7","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"17.0","Tissue RNA - smooth muscle [nTPM]":"19.7","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"29.7","Tissue RNA - stomach 1 [nTPM]":"19.3","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"17.5","Tissue RNA - thyroid gland [nTPM]":"39.5","Tissue RNA - tongue [nTPM]":"31.4","Tissue RNA - tonsil [nTPM]":"11.5","Tissue RNA - urinary bladder [nTPM]":"14.8","Tissue RNA - vagina [nTPM]":"11.8","Tissue RNA - white matter [nTPM]":"18.6","Cell RNA - A-431 [nTPM]":"8.9","Cell RNA - A549 [nTPM]":"11.9","Cell RNA - AF22 [nTPM]":"55.4","Cell RNA - AN3-CA [nTPM]":"17.2","Cell RNA - ASC diff [nTPM]":"21.4","Cell RNA - ASC TERT1 [nTPM]":"23.9","Cell RNA - BEWO [nTPM]":"84.9","Cell RNA - BJ [nTPM]":"17.0","Cell RNA - BJ hTERT+ [nTPM]":"21.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.9","Cell RNA - CACO-2 [nTPM]":"36.7","Cell RNA - CAPAN-2 [nTPM]":"19.4","Cell RNA - Daudi [nTPM]":"50.7","Cell RNA - EFO-21 [nTPM]":"6.1","Cell RNA - fHDF\/TERT166 [nTPM]":"17.0","Cell RNA - GAMG [nTPM]":"22.0","Cell RNA - HaCaT [nTPM]":"8.0","Cell RNA - HAP1 [nTPM]":"19.1","Cell RNA - HBEC3-KT [nTPM]":"21.8","Cell RNA - HBF TERT88 [nTPM]":"18.0","Cell RNA - HDLM-2 [nTPM]":"8.6","Cell RNA - HEK 293 [nTPM]":"13.2","Cell RNA - HEL [nTPM]":"79.0","Cell RNA - HeLa [nTPM]":"25.3","Cell RNA - Hep G2 [nTPM]":"21.4","Cell RNA - HHSteC [nTPM]":"15.5","Cell RNA - HL-60 [nTPM]":"9.7","Cell RNA - HMC-1 [nTPM]":"104.5","Cell RNA - HSkMC [nTPM]":"14.1","Cell RNA - hTCEpi [nTPM]":"12.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.5","Cell RNA - hTERT-HME1 [nTPM]":"12.9","Cell RNA - hTERT-RPE1 [nTPM]":"32.0","Cell RNA - HUVEC TERT2 [nTPM]":"44.1","Cell RNA - JURKAT [nTPM]":"20.7","Cell RNA - K-562 [nTPM]":"17.6","Cell RNA - Karpas-707 [nTPM]":"46.0","Cell RNA - LHCN-M2 [nTPM]":"19.0","Cell RNA - MCF7 [nTPM]":"15.6","Cell RNA - MOLT-4 [nTPM]":"24.1","Cell RNA - NB-4 [nTPM]":"1.5","Cell RNA - NTERA-2 [nTPM]":"23.7","Cell RNA - OE19 [nTPM]":"10.4","Cell RNA - PC-3 [nTPM]":"11.8","Cell RNA - REH [nTPM]":"19.7","Cell RNA - RH-30 [nTPM]":"14.0","Cell RNA - RPMI-8226 [nTPM]":"2.0","Cell RNA - RPTEC TERT1 [nTPM]":"13.6","Cell RNA - RT4 [nTPM]":"20.2","Cell RNA - SCLC-21H [nTPM]":"15.7","Cell RNA - SH-SY5Y [nTPM]":"21.0","Cell RNA - SiHa [nTPM]":"24.9","Cell RNA - SK-BR-3 [nTPM]":"12.1","Cell RNA - SK-MEL-30 [nTPM]":"20.0","Cell RNA - SuSa [nTPM]":"26.5","Cell RNA - T-47d [nTPM]":"6.0","Cell RNA - THP-1 [nTPM]":"6.3","Cell RNA - TIME [nTPM]":"47.0","Cell RNA - U-138 MG [nTPM]":"23.9","Cell RNA - U-2 OS [nTPM]":"25.2","Cell RNA - U-2197 [nTPM]":"30.7","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"51.0","Cell RNA - U-266\/84 [nTPM]":"32.9","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"28.3","Cell RNA - U-937 [nTPM]":"4.1","Cell RNA - WM-115 [nTPM]":"14.8","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"5.9","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"19.8","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"32.1","Brain RNA - hippocampal formation [nTPM]":"27.4","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"18.6","Single Cell Type RNA - Adipocytes [nTPM]":"66.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.1","Single Cell Type RNA - Astrocytes [nTPM]":"110.7","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"19.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"13.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - dendritic cells [nTPM]":"20.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.5","Single Cell Type RNA - Endothelial cells [nTPM]":"49.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"38.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"456.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.6","Single Cell Type RNA - Fibroblasts [nTPM]":"16.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"59.2","Single Cell Type RNA - granulocytes [nTPM]":"51.8","Single Cell Type RNA - Granulosa cells [nTPM]":"22.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"30.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.8","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"264.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"24.6","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"29.5","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"238.9","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"30.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"199.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"236.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.1","Single Cell Type RNA - Paneth cells [nTPM]":"17.7","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"40.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.4","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"7.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.9","Single Cell Type RNA - Urothelial cells [nTPM]":"15.1"},{"Gene":"RAPSN","Gene synonym":["CMS1D","CMS1E","RNF205"],"Ensembl":"ENSG00000165917","Gene description":"Receptor associated protein of the synapse","Uniprot":["Q13702"],"Chromosome":"11","Position":"47437764-47449143","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"skeletal muscle":"88.9","tongue":"33.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Skeletal myocytes":"63.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"RH-30":"238.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039475"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane","Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039475":"AB_10794196"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"2.6","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"88.9","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"33.1","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"59.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"238.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"13.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"63.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"RAX2","Gene synonym":["ARMD6","CORD11","MGC15631","RAXL1"],"Ensembl":"ENSG00000173976","Gene description":"Retina and anterior neural fold homeobox 2","Uniprot":["Q96IS3"],"Chromosome":"19","Position":"3769089-3772228","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Sensory transduction","Transcription","Transcription regulation","Vision"],"Molecular function":["DNA-binding"],"Disease involvement":["Age-related macular degeneration","Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"40","RNA tissue specific nTPM":{"retina":"64.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"123.0","Rod photoreceptor cells":"217.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052533"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA052533":"AB_2681862"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"64.5","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"14.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"123.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"18.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"217.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"RBP3","Gene synonym":["D10S64","D10S65","D10S66","RP66"],"Ensembl":"ENSG00000265203","Gene description":"Retinol binding protein 3","Uniprot":["P10745"],"Chromosome":"10","Position":"47348363-47357881","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"335","RNA tissue specific nTPM":{"retina":"542.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"2070.4","Rod photoreceptor cells":"1610.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hippocampal formation":"1.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041301","HPA044239"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041301":"AB_2677398","HPA044239":"AB_2678868"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"542.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"157.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2070.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"148.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1610.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RD3","Gene synonym":["C1orf36","LCA12"],"Ensembl":"ENSG00000198570","Gene description":"Retinal degeneration 3, GUCY2D regulator","Uniprot":["Q7Z3Z2"],"Chromosome":"1","Position":"211476522-211492162","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"54","RNA tissue specific nTPM":{"retina":"47.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Bipolar cells":"82.7","Cone photoreceptor cells":"100.1","Rod photoreceptor cells":"66.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"4.6","HMC-1":"14.4","SH-SY5Y":"21.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029941","HPA029943"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029941":"AB_2732449","HPA029943":"AB_2732450"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"47.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"4.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"21.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"82.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"100.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"8.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"66.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"RDH12","Gene synonym":["FLJ30273","LCA13","RP53","SDR7C2"],"Ensembl":"ENSG00000139988","Gene description":"Retinol dehydrogenase 12","Uniprot":["Q96NR8"],"Chromosome":"14","Position":"67701886-67734451","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Leber congenital amaurosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"retina":"222.7","skin 1":"63.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"146.0","Rod photoreceptor cells":"453.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"5.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"22.1","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"17.6","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"13.6","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"222.7","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"63.8","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"12.4","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"23.6","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"39.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"146.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"53.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"453.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"RDH5","Gene synonym":["HSD17B9","RDH1","SDR9C5"],"Ensembl":"ENSG00000135437","Gene description":"Retinol dehydrogenase 5","Uniprot":["Q92781"],"Chromosome":"12","Position":"55720367-55724705","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Sensory transduction","Steroid metabolism","Vision"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"94.5","liver":"58.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"62.6","Proximal enterocytes":"49.9","Rod photoreceptor cells":"62.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"28.5","ASC TERT1":"24.3","hTEC\/SVTERT24-B":"15.3","hTERT-RPE1":"24.5","LHCN-M2":"15.4","U-87 MG":"26.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063345"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA063345":"AB_2684992"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"94.5","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"34.2","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"13.6","Tissue RNA - duodenum [nTPM]":"18.5","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"4.6","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"9.2","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"9.0","Tissue RNA - liver [nTPM]":"58.9","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"6.1","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"15.5","Tissue RNA - smooth muscle [nTPM]":"19.5","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"1.4","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"28.5","Cell RNA - ASC TERT1 [nTPM]":"24.3","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"3.8","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"7.9","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"2.1","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"10.5","Cell RNA - hTCEpi [nTPM]":"1.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.3","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"24.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"15.4","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"3.7","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"3.4","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"26.7","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"24.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.9","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"18.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"8.2","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.6","Single Cell Type RNA - Paneth cells [nTPM]":"18.6","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"49.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.9","Single Cell Type RNA - Spermatogonia [nTPM]":"6.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"5.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"RDX","Gene synonym":["DFNB24"],"Ensembl":"ENSG00000137710","Gene description":"Radixin","Uniprot":["P35241"],"Chromosome":"11","Position":"109864295-110296712","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin capping","Actin-binding"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"155.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"484.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000263","HPA000763","CAB037312"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB037312":"AB_261933","HPA000263":"AB_1856043","HPA000763":"AB_1856042"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Tissue RNA - adipose tissue [nTPM]":"40.3","Tissue RNA - adrenal gland [nTPM]":"155.0","Tissue RNA - amygdala [nTPM]":"38.0","Tissue RNA - appendix [nTPM]":"17.4","Tissue RNA - basal ganglia [nTPM]":"57.7","Tissue RNA - bone marrow [nTPM]":"12.0","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"50.0","Tissue RNA - cerebral cortex [nTPM]":"42.7","Tissue RNA - cervix [nTPM]":"32.1","Tissue RNA - choroid plexus [nTPM]":"32.8","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"28.8","Tissue RNA - epididymis [nTPM]":"12.9","Tissue RNA - esophagus [nTPM]":"27.4","Tissue RNA - fallopian tube [nTPM]":"19.7","Tissue RNA - gallbladder [nTPM]":"27.2","Tissue RNA - heart muscle [nTPM]":"41.0","Tissue RNA - hippocampal formation [nTPM]":"35.1","Tissue RNA - hypothalamus [nTPM]":"44.7","Tissue RNA - kidney [nTPM]":"50.2","Tissue RNA - liver [nTPM]":"68.5","Tissue RNA - lung [nTPM]":"48.8","Tissue RNA - lymph node [nTPM]":"11.4","Tissue RNA - medulla oblongata [nTPM]":"52.7","Tissue RNA - midbrain [nTPM]":"48.2","Tissue RNA - ovary [nTPM]":"52.8","Tissue RNA - pancreas [nTPM]":"52.7","Tissue RNA - parathyroid gland [nTPM]":"33.2","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"35.3","Tissue RNA - pons [nTPM]":"54.3","Tissue RNA - prostate [nTPM]":"25.4","Tissue RNA - rectum [nTPM]":"11.1","Tissue RNA - retina [nTPM]":"19.2","Tissue RNA - salivary gland [nTPM]":"20.8","Tissue RNA - seminal vesicle [nTPM]":"26.0","Tissue RNA - skeletal muscle [nTPM]":"82.1","Tissue RNA - skin 1 [nTPM]":"11.9","Tissue RNA - small intestine [nTPM]":"7.4","Tissue RNA - smooth muscle [nTPM]":"35.0","Tissue RNA - spinal cord [nTPM]":"45.1","Tissue RNA - spleen [nTPM]":"26.6","Tissue RNA - stomach 1 [nTPM]":"15.0","Tissue RNA - testis [nTPM]":"33.7","Tissue RNA - thalamus [nTPM]":"47.7","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"45.7","Tissue RNA - tongue [nTPM]":"59.7","Tissue RNA - tonsil [nTPM]":"14.6","Tissue RNA - urinary bladder [nTPM]":"27.1","Tissue RNA - vagina [nTPM]":"10.1","Tissue RNA - white matter [nTPM]":"77.6","Cell RNA - A-431 [nTPM]":"69.6","Cell RNA - A549 [nTPM]":"35.3","Cell RNA - AF22 [nTPM]":"137.3","Cell RNA - AN3-CA [nTPM]":"54.8","Cell RNA - ASC diff [nTPM]":"78.8","Cell RNA - ASC TERT1 [nTPM]":"87.4","Cell RNA - BEWO [nTPM]":"79.3","Cell RNA - BJ [nTPM]":"85.8","Cell RNA - BJ hTERT+ [nTPM]":"47.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"54.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.2","Cell RNA - CACO-2 [nTPM]":"99.7","Cell RNA - CAPAN-2 [nTPM]":"115.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"127.4","Cell RNA - fHDF\/TERT166 [nTPM]":"104.7","Cell RNA - GAMG [nTPM]":"84.9","Cell RNA - HaCaT [nTPM]":"61.5","Cell RNA - HAP1 [nTPM]":"77.3","Cell RNA - HBEC3-KT [nTPM]":"80.4","Cell RNA - HBF TERT88 [nTPM]":"80.5","Cell RNA - HDLM-2 [nTPM]":"41.9","Cell RNA - HEK 293 [nTPM]":"44.2","Cell RNA - HEL [nTPM]":"51.5","Cell RNA - HeLa [nTPM]":"107.7","Cell RNA - Hep G2 [nTPM]":"74.1","Cell RNA - HHSteC [nTPM]":"73.6","Cell RNA - HL-60 [nTPM]":"19.0","Cell RNA - HMC-1 [nTPM]":"33.2","Cell RNA - HSkMC [nTPM]":"89.7","Cell RNA - hTCEpi [nTPM]":"45.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.0","Cell RNA - hTERT-HME1 [nTPM]":"120.1","Cell RNA - hTERT-RPE1 [nTPM]":"89.3","Cell RNA - HUVEC TERT2 [nTPM]":"149.8","Cell RNA - JURKAT [nTPM]":"11.1","Cell RNA - K-562 [nTPM]":"73.5","Cell RNA - Karpas-707 [nTPM]":"29.5","Cell RNA - LHCN-M2 [nTPM]":"127.0","Cell RNA - MCF7 [nTPM]":"120.0","Cell RNA - MOLT-4 [nTPM]":"11.0","Cell RNA - NB-4 [nTPM]":"15.6","Cell RNA - NTERA-2 [nTPM]":"44.0","Cell RNA - OE19 [nTPM]":"4.0","Cell RNA - PC-3 [nTPM]":"58.4","Cell RNA - REH [nTPM]":"31.2","Cell RNA - RH-30 [nTPM]":"96.8","Cell RNA - RPMI-8226 [nTPM]":"30.1","Cell RNA - RPTEC TERT1 [nTPM]":"68.1","Cell RNA - RT4 [nTPM]":"33.5","Cell RNA - SCLC-21H [nTPM]":"37.2","Cell RNA - SH-SY5Y [nTPM]":"40.5","Cell RNA - SiHa [nTPM]":"148.5","Cell RNA - SK-BR-3 [nTPM]":"65.9","Cell RNA - SK-MEL-30 [nTPM]":"52.7","Cell RNA - SuSa [nTPM]":"102.5","Cell RNA - T-47d [nTPM]":"85.0","Cell RNA - THP-1 [nTPM]":"29.9","Cell RNA - TIME [nTPM]":"92.6","Cell RNA - U-138 MG [nTPM]":"89.5","Cell RNA - U-2 OS [nTPM]":"66.8","Cell RNA - U-2197 [nTPM]":"43.9","Cell RNA - U-251 MG [nTPM]":"67.4","Cell RNA - U-266\/70 [nTPM]":"9.5","Cell RNA - U-266\/84 [nTPM]":"17.3","Cell RNA - U-698 [nTPM]":"65.9","Cell RNA - U-87 MG [nTPM]":"34.2","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"210.9","Blood RNA - basophil [nTPM]":"29.5","Blood RNA - classical monocyte [nTPM]":"14.8","Blood RNA - eosinophil [nTPM]":"22.0","Blood RNA - gdT-cell [nTPM]":"11.6","Blood RNA - intermediate monocyte [nTPM]":"12.5","Blood RNA - MAIT T-cell [nTPM]":"15.5","Blood RNA - memory B-cell [nTPM]":"11.5","Blood RNA - memory CD4 T-cell [nTPM]":"10.2","Blood RNA - memory CD8 T-cell [nTPM]":"8.8","Blood RNA - myeloid DC [nTPM]":"12.8","Blood RNA - naive B-cell [nTPM]":"8.3","Blood RNA - naive CD4 T-cell [nTPM]":"6.8","Blood RNA - naive CD8 T-cell [nTPM]":"5.8","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"17.6","Blood RNA - non-classical monocyte [nTPM]":"9.9","Blood RNA - plasmacytoid DC [nTPM]":"10.3","Blood RNA - T-reg [nTPM]":"22.0","Blood RNA - total PBMC [nTPM]":"8.4","Brain RNA - amygdala [nTPM]":"38.0","Brain RNA - basal ganglia [nTPM]":"57.7","Brain RNA - cerebellum [nTPM]":"50.0","Brain RNA - cerebral cortex [nTPM]":"42.7","Brain RNA - hippocampal formation [nTPM]":"35.1","Brain RNA - hypothalamus [nTPM]":"44.7","Brain RNA - medulla oblongata [nTPM]":"52.7","Brain RNA - midbrain [nTPM]":"48.2","Brain RNA - pons [nTPM]":"54.3","Brain RNA - spinal cord [nTPM]":"45.1","Brain RNA - thalamus [nTPM]":"47.7","Brain RNA - white matter [nTPM]":"77.6","Single Cell Type RNA - Adipocytes [nTPM]":"248.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"484.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"98.8","Single Cell Type RNA - Astrocytes [nTPM]":"53.5","Single Cell Type RNA - B-cells [nTPM]":"30.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"124.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"56.9","Single Cell Type RNA - Bipolar cells [nTPM]":"85.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"47.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"159.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"70.1","Single Cell Type RNA - Club cells [nTPM]":"77.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"75.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"122.1","Single Cell Type RNA - dendritic cells [nTPM]":"21.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"109.5","Single Cell Type RNA - Ductal cells [nTPM]":"128.1","Single Cell Type RNA - Early spermatids [nTPM]":"15.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"109.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"117.2","Single Cell Type RNA - Endothelial cells [nTPM]":"289.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.2","Single Cell Type RNA - Erythroid cells [nTPM]":"104.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"423.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"189.8","Single Cell Type RNA - Fibroblasts [nTPM]":"88.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"135.3","Single Cell Type RNA - granulocytes [nTPM]":"67.2","Single Cell Type RNA - Granulosa cells [nTPM]":"132.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"319.2","Single Cell Type RNA - Hepatocytes [nTPM]":"260.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"85.1","Single Cell Type RNA - Horizontal cells [nTPM]":"101.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"57.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"61.1","Single Cell Type RNA - Kupffer cells [nTPM]":"103.2","Single Cell Type RNA - Langerhans cells [nTPM]":"59.9","Single Cell Type RNA - Late spermatids [nTPM]":"43.6","Single Cell Type RNA - Leydig cells [nTPM]":"275.2","Single Cell Type RNA - Macrophages [nTPM]":"71.6","Single Cell Type RNA - Melanocytes [nTPM]":"72.9","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"135.4","Single Cell Type RNA - Muller glia cells [nTPM]":"77.0","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"68.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"229.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"134.3","Single Cell Type RNA - Paneth cells [nTPM]":"22.1","Single Cell Type RNA - Peritubular cells [nTPM]":"266.7","Single Cell Type RNA - Plasma cells [nTPM]":"36.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"65.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"236.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"52.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"94.8","Single Cell Type RNA - Sertoli cells [nTPM]":"124.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"74.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"143.8","Single Cell Type RNA - Spermatocytes [nTPM]":"73.9","Single Cell Type RNA - Spermatogonia [nTPM]":"257.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"52.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"227.3","Single Cell Type RNA - T-cells [nTPM]":"29.2","Single Cell Type RNA - Theca cells [nTPM]":"229.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.8","Single Cell Type RNA - Urothelial cells [nTPM]":"45.9"},{"Gene":"REEP1","Gene synonym":["C2orf23","FLJ13110","SPG31","Yip2a"],"Ensembl":"ENSG00000068615","Gene description":"Receptor accessory protein 1","Uniprot":["Q9H902"],"Chromosome":"2","Position":"86213993-86338083","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"50.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"86.2","Inhibitory neurons":"95.5","Oligodendrocyte precursor cells":"39.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"7.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"68.1","HAP1":"15.0","RPMI-8226":"16.0","SCLC-21H":"32.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058061"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058061":"AB_2683591"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"17.0","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"15.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"30.4","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"11.5","Tissue RNA - colon [nTPM]":"42.4","Tissue RNA - duodenum [nTPM]":"4.4","Tissue RNA - endometrium 1 [nTPM]":"18.9","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"6.2","Tissue RNA - fallopian tube [nTPM]":"13.6","Tissue RNA - gallbladder [nTPM]":"3.8","Tissue RNA - heart muscle [nTPM]":"16.6","Tissue RNA - hippocampal formation [nTPM]":"15.4","Tissue RNA - hypothalamus [nTPM]":"44.0","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"3.6","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"24.6","Tissue RNA - midbrain [nTPM]":"38.1","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"13.9","Tissue RNA - placenta [nTPM]":"2.2","Tissue RNA - pons [nTPM]":"50.0","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"12.9","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"12.9","Tissue RNA - skeletal muscle [nTPM]":"19.8","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"20.7","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"8.8","Tissue RNA - testis [nTPM]":"44.5","Tissue RNA - thalamus [nTPM]":"18.7","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"14.3","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"21.7","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"2.2","Cell RNA - AN3-CA [nTPM]":"2.9","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"68.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"2.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.4","Cell RNA - HaCaT [nTPM]":"4.9","Cell RNA - HAP1 [nTPM]":"15.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"8.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"5.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"2.7","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"6.5","Cell RNA - RPMI-8226 [nTPM]":"16.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"32.0","Cell RNA - SH-SY5Y [nTPM]":"3.1","Cell RNA - SiHa [nTPM]":"3.5","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"5.1","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.3","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"6.3","Cell RNA - U-266\/70 [nTPM]":"7.2","Cell RNA - U-266\/84 [nTPM]":"5.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"17.0","Brain RNA - basal ganglia [nTPM]":"15.8","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"30.4","Brain RNA - hippocampal formation [nTPM]":"15.4","Brain RNA - hypothalamus [nTPM]":"44.0","Brain RNA - medulla oblongata [nTPM]":"24.6","Brain RNA - midbrain [nTPM]":"38.1","Brain RNA - pons [nTPM]":"50.0","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"18.7","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"1.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"18.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"86.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.6","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"95.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"14.4","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.5","Single Cell Type RNA - Spermatocytes [nTPM]":"4.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"REEP2","Gene synonym":["C5orf19","SGC32445","SPG72","Yip2d"],"Ensembl":"ENSG00000132563","Gene description":"Receptor accessory protein 2","Uniprot":["Q9BRK0"],"Chromosome":"5","Position":"138439057-138446969","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"155.7","choroid plexus":"77.8","retina":"61.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"47.3","Cone photoreceptor cells":"70.9","Excitatory neurons":"51.2","Horizontal cells":"48.8","Inhibitory neurons":"46.1","Muller glia cells":"29.8","Rod photoreceptor cells":"73.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"31.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"97.3","SCLC-21H":"40.5","SH-SY5Y":"46.1","U-87 MG":"36.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031813","HPA076571"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA031813":"AB_2674054","HPA076571":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.83e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.65e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.31e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.6","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"106.7","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"102.5","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"93.5","Tissue RNA - cerebral cortex [nTPM]":"155.7","Tissue RNA - cervix [nTPM]":"3.6","Tissue RNA - choroid plexus [nTPM]":"77.8","Tissue RNA - colon [nTPM]":"18.8","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"7.0","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"3.6","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"24.8","Tissue RNA - hippocampal formation [nTPM]":"110.3","Tissue RNA - hypothalamus [nTPM]":"110.7","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"134.6","Tissue RNA - midbrain [nTPM]":"109.1","Tissue RNA - ovary [nTPM]":"4.0","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"1.8","Tissue RNA - pituitary gland [nTPM]":"54.5","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"136.4","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"61.2","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"16.6","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"4.3","Tissue RNA - smooth muscle [nTPM]":"12.6","Tissue RNA - spinal cord [nTPM]":"77.5","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"7.6","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"130.6","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"5.7","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"4.6","Tissue RNA - white matter [nTPM]":"104.7","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"7.4","Cell RNA - AF22 [nTPM]":"27.6","Cell RNA - AN3-CA [nTPM]":"97.3","Cell RNA - ASC diff [nTPM]":"3.9","Cell RNA - ASC TERT1 [nTPM]":"10.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"8.4","Cell RNA - BJ hTERT+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.9","Cell RNA - CACO-2 [nTPM]":"5.3","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"10.5","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"26.1","Cell RNA - HBEC3-KT [nTPM]":"5.4","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"3.1","Cell RNA - HEK 293 [nTPM]":"23.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"12.6","Cell RNA - HHSteC [nTPM]":"9.8","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"3.2","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.4","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"19.9","Cell RNA - HUVEC TERT2 [nTPM]":"2.3","Cell RNA - JURKAT [nTPM]":"27.6","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"3.6","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"2.7","Cell RNA - NB-4 [nTPM]":"1.8","Cell RNA - NTERA-2 [nTPM]":"17.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"40.5","Cell RNA - SH-SY5Y [nTPM]":"46.1","Cell RNA - SiHa [nTPM]":"2.9","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"7.5","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"2.6","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"6.6","Cell RNA - U-2 OS [nTPM]":"6.6","Cell RNA - U-2197 [nTPM]":"6.4","Cell RNA - U-251 MG [nTPM]":"15.9","Cell RNA - U-266\/70 [nTPM]":"18.1","Cell RNA - U-266\/84 [nTPM]":"12.3","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"36.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"106.7","Brain RNA - basal ganglia [nTPM]":"102.5","Brain RNA - cerebellum [nTPM]":"93.5","Brain RNA - cerebral cortex [nTPM]":"155.7","Brain RNA - hippocampal formation [nTPM]":"110.3","Brain RNA - hypothalamus [nTPM]":"110.7","Brain RNA - medulla oblongata [nTPM]":"134.6","Brain RNA - midbrain [nTPM]":"109.1","Brain RNA - pons [nTPM]":"136.4","Brain RNA - spinal cord [nTPM]":"77.5","Brain RNA - thalamus [nTPM]":"130.6","Brain RNA - white matter [nTPM]":"104.7","Single Cell Type RNA - Adipocytes [nTPM]":"17.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"18.9","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"47.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"29.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"9.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"REEP6","Gene synonym":["C19orf32","DP1L1","FLJ25383","Yip2f"],"Ensembl":"ENSG00000115255","Gene description":"Receptor accessory protein 6","Uniprot":["Q96HR9"],"Chromosome":"19","Position":"1491166-1497927","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"217.5","liver":"398.0","testis":"283.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"559.1","Late spermatids":"3135.0","Proximal enterocytes":"898.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"114.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"57.9","Hep G2":"56.2","K-562":"155.7","T-47d":"121.4"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003895","HPA048015"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA003895":"AB_1845723","HPA048015":"AB_2680233"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.4","Tissue RNA - adrenal gland [nTPM]":"86.5","Tissue RNA - amygdala [nTPM]":"11.1","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"12.4","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"17.5","Tissue RNA - cerebellum [nTPM]":"10.1","Tissue RNA - cerebral cortex [nTPM]":"18.0","Tissue RNA - cervix [nTPM]":"5.6","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"3.0","Tissue RNA - duodenum [nTPM]":"217.5","Tissue RNA - endometrium 1 [nTPM]":"3.5","Tissue RNA - epididymis [nTPM]":"14.6","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"4.6","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"12.7","Tissue RNA - hypothalamus [nTPM]":"8.8","Tissue RNA - kidney [nTPM]":"22.1","Tissue RNA - liver [nTPM]":"398.0","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"10.1","Tissue RNA - ovary [nTPM]":"7.7","Tissue RNA - pancreas [nTPM]":"28.5","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"20.1","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"94.0","Tissue RNA - salivary gland [nTPM]":"17.9","Tissue RNA - seminal vesicle [nTPM]":"6.8","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"9.3","Tissue RNA - small intestine [nTPM]":"199.6","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"8.4","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"4.2","Tissue RNA - testis [nTPM]":"283.9","Tissue RNA - thalamus [nTPM]":"12.1","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"9.2","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"10.9","Cell RNA - A-431 [nTPM]":"7.3","Cell RNA - A549 [nTPM]":"9.2","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"34.3","Cell RNA - ASC diff [nTPM]":"5.6","Cell RNA - ASC TERT1 [nTPM]":"2.0","Cell RNA - BEWO [nTPM]":"39.5","Cell RNA - BJ [nTPM]":"1.8","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.9","Cell RNA - CACO-2 [nTPM]":"57.9","Cell RNA - CAPAN-2 [nTPM]":"22.5","Cell RNA - Daudi [nTPM]":"3.9","Cell RNA - EFO-21 [nTPM]":"12.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1.1","Cell RNA - GAMG [nTPM]":"2.3","Cell RNA - HaCaT [nTPM]":"7.3","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"1.9","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"21.3","Cell RNA - HeLa [nTPM]":"1.3","Cell RNA - Hep G2 [nTPM]":"56.2","Cell RNA - HHSteC [nTPM]":"4.2","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"6.6","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"4.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"3.2","Cell RNA - HUVEC TERT2 [nTPM]":"1.1","Cell RNA - JURKAT [nTPM]":"4.9","Cell RNA - K-562 [nTPM]":"155.7","Cell RNA - Karpas-707 [nTPM]":"5.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"29.6","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"4.7","Cell RNA - NTERA-2 [nTPM]":"12.8","Cell RNA - OE19 [nTPM]":"21.1","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"4.9","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"10.0","Cell RNA - RPTEC TERT1 [nTPM]":"10.9","Cell RNA - RT4 [nTPM]":"2.7","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"17.2","Cell RNA - SiHa [nTPM]":"9.8","Cell RNA - SK-BR-3 [nTPM]":"14.2","Cell RNA - SK-MEL-30 [nTPM]":"6.3","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"121.4","Cell RNA - THP-1 [nTPM]":"5.7","Cell RNA - TIME [nTPM]":"3.4","Cell RNA - U-138 MG [nTPM]":"2.8","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"8.7","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"16.4","Cell RNA - U-266\/84 [nTPM]":"5.3","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"11.2","Cell RNA - U-937 [nTPM]":"9.4","Cell RNA - WM-115 [nTPM]":"8.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"5.5","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"4.9","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"11.1","Brain RNA - basal ganglia [nTPM]":"12.4","Brain RNA - cerebellum [nTPM]":"10.1","Brain RNA - cerebral cortex [nTPM]":"18.0","Brain RNA - hippocampal formation [nTPM]":"12.7","Brain RNA - hypothalamus [nTPM]":"8.8","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"10.1","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"8.4","Brain RNA - thalamus [nTPM]":"12.1","Brain RNA - white matter [nTPM]":"10.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"2.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"30.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"47.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"91.5","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"69.4","Single Cell Type RNA - dendritic cells [nTPM]":"2.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"34.5","Single Cell Type RNA - Early spermatids [nTPM]":"559.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"69.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.8","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.0","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"132.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"267.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.6","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"51.9","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.3","Single Cell Type RNA - Late spermatids [nTPM]":"3135.0","Single Cell Type RNA - Leydig cells [nTPM]":"34.2","Single Cell Type RNA - Macrophages [nTPM]":"4.1","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.7","Single Cell Type RNA - Muller glia cells [nTPM]":"44.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.0","Single Cell Type RNA - Paneth cells [nTPM]":"53.6","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"898.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"292.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.3","Single Cell Type RNA - Spermatocytes [nTPM]":"29.9","Single Cell Type RNA - Spermatogonia [nTPM]":"36.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - T-cells [nTPM]":"4.3","Single Cell Type RNA - Theca cells [nTPM]":"50.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"70.7","Single Cell Type RNA - Urothelial cells [nTPM]":"14.7"},{"Gene":"RELN","Gene synonym":["PRO1598","RL"],"Ensembl":"ENSG00000189056","Gene description":"Reelin","Uniprot":["P78509"],"Chromosome":"7","Position":"103471381-103989658","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Developmental protein","Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Epilepsy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"64.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hepatic stellate cells":"128.5","Inhibitory neurons":"372.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"5.7"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"cerebellum":"64.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"16.2","PC-3":"8.6","SCLC-21H":"11.1","SH-SY5Y":"13.7","TIME":"33.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"110.0"},"Antibody":["HPA077891"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"30000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA077891":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"64.4","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"1.5","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"1.7","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"13.4","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"6.3","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"3.9","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"5.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"2.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"4.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"16.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"8.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"11.1","Cell RNA - SH-SY5Y [nTPM]":"13.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"33.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"64.4","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"6.3","Brain RNA - spinal cord [nTPM]":"3.9","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"30.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"13.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"7.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"128.5","Single Cell Type RNA - Hepatocytes [nTPM]":"3.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"372.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"6.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"REPS1","Gene synonym":[],"Ensembl":"ENSG00000135597","Gene description":"RALBP1 associated Eps domain containing 1","Uniprot":["Q96D71"],"Chromosome":"6","Position":"138903493-138988261","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"207.3","Excitatory neurons":"114.3","Inhibitory neurons":"138.1","Oligodendrocyte precursor cells":"99.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029961","HPA029962"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029961":"AB_10603233","HPA029962":"AB_2673269"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.5","Tissue RNA - adrenal gland [nTPM]":"11.9","Tissue RNA - amygdala [nTPM]":"24.7","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"25.4","Tissue RNA - bone marrow [nTPM]":"23.2","Tissue RNA - breast [nTPM]":"23.6","Tissue RNA - cerebellum [nTPM]":"27.7","Tissue RNA - cerebral cortex [nTPM]":"36.8","Tissue RNA - cervix [nTPM]":"19.2","Tissue RNA - choroid plexus [nTPM]":"14.8","Tissue RNA - colon [nTPM]":"17.4","Tissue RNA - duodenum [nTPM]":"15.4","Tissue RNA - endometrium 1 [nTPM]":"21.9","Tissue RNA - epididymis [nTPM]":"40.2","Tissue RNA - esophagus [nTPM]":"28.0","Tissue RNA - fallopian tube [nTPM]":"18.4","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"23.9","Tissue RNA - hippocampal formation [nTPM]":"27.4","Tissue RNA - hypothalamus [nTPM]":"24.0","Tissue RNA - kidney [nTPM]":"17.4","Tissue RNA - liver [nTPM]":"31.3","Tissue RNA - lung [nTPM]":"15.2","Tissue RNA - lymph node [nTPM]":"19.4","Tissue RNA - medulla oblongata [nTPM]":"25.2","Tissue RNA - midbrain [nTPM]":"23.9","Tissue RNA - ovary [nTPM]":"21.1","Tissue RNA - pancreas [nTPM]":"18.8","Tissue RNA - parathyroid gland [nTPM]":"41.0","Tissue RNA - pituitary gland [nTPM]":"31.7","Tissue RNA - placenta [nTPM]":"17.2","Tissue RNA - pons [nTPM]":"21.3","Tissue RNA - prostate [nTPM]":"15.9","Tissue RNA - rectum [nTPM]":"17.3","Tissue RNA - retina [nTPM]":"38.8","Tissue RNA - salivary gland [nTPM]":"26.1","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"17.5","Tissue RNA - skin 1 [nTPM]":"30.0","Tissue RNA - small intestine [nTPM]":"16.4","Tissue RNA - smooth muscle [nTPM]":"19.5","Tissue RNA - spinal cord [nTPM]":"21.5","Tissue RNA - spleen [nTPM]":"22.1","Tissue RNA - stomach 1 [nTPM]":"18.1","Tissue RNA - testis [nTPM]":"35.6","Tissue RNA - thalamus [nTPM]":"25.9","Tissue RNA - thymus [nTPM]":"36.0","Tissue RNA - thyroid gland [nTPM]":"17.8","Tissue RNA - tongue [nTPM]":"12.6","Tissue RNA - tonsil [nTPM]":"22.2","Tissue RNA - urinary bladder [nTPM]":"19.5","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"25.3","Cell RNA - A-431 [nTPM]":"29.3","Cell RNA - A549 [nTPM]":"22.6","Cell RNA - AF22 [nTPM]":"42.3","Cell RNA - AN3-CA [nTPM]":"53.1","Cell RNA - ASC diff [nTPM]":"23.4","Cell RNA - ASC TERT1 [nTPM]":"41.6","Cell RNA - BEWO [nTPM]":"46.2","Cell RNA - BJ [nTPM]":"27.8","Cell RNA - BJ hTERT+ [nTPM]":"30.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.2","Cell RNA - CACO-2 [nTPM]":"54.1","Cell RNA - CAPAN-2 [nTPM]":"24.8","Cell RNA - Daudi [nTPM]":"35.2","Cell RNA - EFO-21 [nTPM]":"22.9","Cell RNA - fHDF\/TERT166 [nTPM]":"38.9","Cell RNA - GAMG [nTPM]":"38.0","Cell RNA - HaCaT [nTPM]":"33.6","Cell RNA - HAP1 [nTPM]":"48.7","Cell RNA - HBEC3-KT [nTPM]":"42.0","Cell RNA - HBF TERT88 [nTPM]":"42.1","Cell RNA - HDLM-2 [nTPM]":"37.6","Cell RNA - HEK 293 [nTPM]":"41.9","Cell RNA - HEL [nTPM]":"29.6","Cell RNA - HeLa [nTPM]":"12.9","Cell RNA - Hep G2 [nTPM]":"32.9","Cell RNA - HHSteC [nTPM]":"35.3","Cell RNA - HL-60 [nTPM]":"94.6","Cell RNA - HMC-1 [nTPM]":"45.9","Cell RNA - HSkMC [nTPM]":"34.1","Cell RNA - hTCEpi [nTPM]":"33.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"58.6","Cell RNA - hTERT-HME1 [nTPM]":"70.3","Cell RNA - hTERT-RPE1 [nTPM]":"30.2","Cell RNA - HUVEC TERT2 [nTPM]":"33.5","Cell RNA - JURKAT [nTPM]":"51.2","Cell RNA - K-562 [nTPM]":"40.2","Cell RNA - Karpas-707 [nTPM]":"35.1","Cell RNA - LHCN-M2 [nTPM]":"41.4","Cell RNA - MCF7 [nTPM]":"49.4","Cell RNA - MOLT-4 [nTPM]":"53.9","Cell RNA - NB-4 [nTPM]":"51.3","Cell RNA - NTERA-2 [nTPM]":"40.4","Cell RNA - OE19 [nTPM]":"37.4","Cell RNA - PC-3 [nTPM]":"21.3","Cell RNA - REH [nTPM]":"62.4","Cell RNA - RH-30 [nTPM]":"26.0","Cell RNA - RPMI-8226 [nTPM]":"20.0","Cell RNA - RPTEC TERT1 [nTPM]":"26.5","Cell RNA - RT4 [nTPM]":"43.6","Cell RNA - SCLC-21H [nTPM]":"37.7","Cell RNA - SH-SY5Y [nTPM]":"37.2","Cell RNA - SiHa [nTPM]":"25.7","Cell RNA - SK-BR-3 [nTPM]":"38.7","Cell RNA - SK-MEL-30 [nTPM]":"38.0","Cell RNA - SuSa [nTPM]":"62.0","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"64.4","Cell RNA - TIME [nTPM]":"32.9","Cell RNA - U-138 MG [nTPM]":"17.8","Cell RNA - U-2 OS [nTPM]":"29.6","Cell RNA - U-2197 [nTPM]":"48.5","Cell RNA - U-251 MG [nTPM]":"38.8","Cell RNA - U-266\/70 [nTPM]":"34.4","Cell RNA - U-266\/84 [nTPM]":"33.7","Cell RNA - U-698 [nTPM]":"49.2","Cell RNA - U-87 MG [nTPM]":"21.1","Cell RNA - U-937 [nTPM]":"38.3","Cell RNA - WM-115 [nTPM]":"26.4","Blood RNA - basophil [nTPM]":"5.9","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"4.0","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.9","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"4.5","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"24.7","Brain RNA - basal ganglia [nTPM]":"25.4","Brain RNA - cerebellum [nTPM]":"27.7","Brain RNA - cerebral cortex [nTPM]":"36.8","Brain RNA - hippocampal formation [nTPM]":"27.4","Brain RNA - hypothalamus [nTPM]":"24.0","Brain RNA - medulla oblongata [nTPM]":"25.2","Brain RNA - midbrain [nTPM]":"23.9","Brain RNA - pons [nTPM]":"21.3","Brain RNA - spinal cord [nTPM]":"21.5","Brain RNA - thalamus [nTPM]":"25.9","Brain RNA - white matter [nTPM]":"25.3","Single Cell Type RNA - Adipocytes [nTPM]":"11.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.4","Single Cell Type RNA - Astrocytes [nTPM]":"207.3","Single Cell Type RNA - B-cells [nTPM]":"18.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"12.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.8","Single Cell Type RNA - Early spermatids [nTPM]":"13.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"114.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.3","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.3","Single Cell Type RNA - granulocytes [nTPM]":"15.9","Single Cell Type RNA - Granulosa cells [nTPM]":"14.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"43.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.3","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"138.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"24.0","Single Cell Type RNA - Langerhans cells [nTPM]":"10.3","Single Cell Type RNA - Late spermatids [nTPM]":"7.7","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"17.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"47.8","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"36.8","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"99.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"71.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"14.7","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"23.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.9","Single Cell Type RNA - Spermatocytes [nTPM]":"41.7","Single Cell Type RNA - Spermatogonia [nTPM]":"33.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.6","Single Cell Type RNA - T-cells [nTPM]":"18.7","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.2","Single Cell Type RNA - Urothelial cells [nTPM]":"18.1"},{"Gene":"REST","Gene synonym":["DFNA27","NRSF","XBR"],"Ensembl":"ENSG00000084093","Gene description":"RE1 silencing transcription factor","Uniprot":["Q13127"],"Chromosome":"4","Position":"56907876-56966808","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Repressor"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006079","CAB068222"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB068222":"AB_2665651","HPA006079":"AB_1079801"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.50e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.9","Tissue RNA - adrenal gland [nTPM]":"5.5","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"9.4","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"24.8","Tissue RNA - breast [nTPM]":"9.8","Tissue RNA - cerebellum [nTPM]":"6.3","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"8.9","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"7.9","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"5.0","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"11.5","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"13.4","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"11.2","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"13.8","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"9.9","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"10.0","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"8.9","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"10.7","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"18.1","Tissue RNA - thyroid gland [nTPM]":"10.9","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"13.6","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"2.1","Tissue RNA - white matter [nTPM]":"7.4","Cell RNA - A-431 [nTPM]":"10.8","Cell RNA - A549 [nTPM]":"13.0","Cell RNA - AF22 [nTPM]":"17.4","Cell RNA - AN3-CA [nTPM]":"18.2","Cell RNA - ASC diff [nTPM]":"13.2","Cell RNA - ASC TERT1 [nTPM]":"16.0","Cell RNA - BEWO [nTPM]":"22.7","Cell RNA - BJ [nTPM]":"15.6","Cell RNA - BJ hTERT+ [nTPM]":"13.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.7","Cell RNA - CACO-2 [nTPM]":"11.5","Cell RNA - CAPAN-2 [nTPM]":"16.5","Cell RNA - Daudi [nTPM]":"24.5","Cell RNA - EFO-21 [nTPM]":"23.5","Cell RNA - fHDF\/TERT166 [nTPM]":"16.8","Cell RNA - GAMG [nTPM]":"10.7","Cell RNA - HaCaT [nTPM]":"9.8","Cell RNA - HAP1 [nTPM]":"13.2","Cell RNA - HBEC3-KT [nTPM]":"16.3","Cell RNA - HBF TERT88 [nTPM]":"24.4","Cell RNA - HDLM-2 [nTPM]":"12.6","Cell RNA - HEK 293 [nTPM]":"8.1","Cell RNA - HEL [nTPM]":"22.0","Cell RNA - HeLa [nTPM]":"9.4","Cell RNA - Hep G2 [nTPM]":"12.5","Cell RNA - HHSteC [nTPM]":"16.2","Cell RNA - HL-60 [nTPM]":"29.0","Cell RNA - HMC-1 [nTPM]":"13.5","Cell RNA - HSkMC [nTPM]":"16.5","Cell RNA - hTCEpi [nTPM]":"14.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.1","Cell RNA - hTERT-HME1 [nTPM]":"16.0","Cell RNA - hTERT-RPE1 [nTPM]":"20.5","Cell RNA - HUVEC TERT2 [nTPM]":"20.1","Cell RNA - JURKAT [nTPM]":"19.0","Cell RNA - K-562 [nTPM]":"14.3","Cell RNA - Karpas-707 [nTPM]":"26.3","Cell RNA - LHCN-M2 [nTPM]":"19.0","Cell RNA - MCF7 [nTPM]":"17.3","Cell RNA - MOLT-4 [nTPM]":"31.5","Cell RNA - NB-4 [nTPM]":"21.3","Cell RNA - NTERA-2 [nTPM]":"15.2","Cell RNA - OE19 [nTPM]":"12.3","Cell RNA - PC-3 [nTPM]":"8.9","Cell RNA - REH [nTPM]":"30.0","Cell RNA - RH-30 [nTPM]":"14.5","Cell RNA - RPMI-8226 [nTPM]":"8.1","Cell RNA - RPTEC TERT1 [nTPM]":"19.0","Cell RNA - RT4 [nTPM]":"18.3","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"8.1","Cell RNA - SiHa [nTPM]":"17.8","Cell RNA - SK-BR-3 [nTPM]":"18.8","Cell RNA - SK-MEL-30 [nTPM]":"14.6","Cell RNA - SuSa [nTPM]":"24.8","Cell RNA - T-47d [nTPM]":"19.3","Cell RNA - THP-1 [nTPM]":"20.3","Cell RNA - TIME [nTPM]":"28.7","Cell RNA - U-138 MG [nTPM]":"20.4","Cell RNA - U-2 OS [nTPM]":"18.1","Cell RNA - U-2197 [nTPM]":"12.4","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"10.8","Cell RNA - U-266\/84 [nTPM]":"7.8","Cell RNA - U-698 [nTPM]":"15.1","Cell RNA - U-87 MG [nTPM]":"13.2","Cell RNA - U-937 [nTPM]":"16.7","Cell RNA - WM-115 [nTPM]":"10.8","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"7.2","Blood RNA - gdT-cell [nTPM]":"6.2","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"6.2","Blood RNA - memory B-cell [nTPM]":"11.6","Blood RNA - memory CD4 T-cell [nTPM]":"6.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.9","Blood RNA - myeloid DC [nTPM]":"5.2","Blood RNA - naive B-cell [nTPM]":"21.1","Blood RNA - naive CD4 T-cell [nTPM]":"10.8","Blood RNA - naive CD8 T-cell [nTPM]":"4.4","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"6.1","Blood RNA - non-classical monocyte [nTPM]":"7.9","Blood RNA - plasmacytoid DC [nTPM]":"6.0","Blood RNA - T-reg [nTPM]":"9.4","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"6.3","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"5.0","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"7.4","Single Cell Type RNA - Adipocytes [nTPM]":"38.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"60.2","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"51.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"57.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"99.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"35.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"50.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"43.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"81.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"58.0","Single Cell Type RNA - dendritic cells [nTPM]":"65.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"58.4","Single Cell Type RNA - Early spermatids [nTPM]":"9.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"64.3","Single Cell Type RNA - Endothelial cells [nTPM]":"50.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"54.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"57.1","Single Cell Type RNA - Fibroblasts [nTPM]":"40.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.4","Single Cell Type RNA - granulocytes [nTPM]":"51.4","Single Cell Type RNA - Granulosa cells [nTPM]":"56.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.2","Single Cell Type RNA - Hepatocytes [nTPM]":"31.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.5","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"36.2","Single Cell Type RNA - Langerhans cells [nTPM]":"37.9","Single Cell Type RNA - Late spermatids [nTPM]":"11.9","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"44.0","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"78.0","Single Cell Type RNA - Muller glia cells [nTPM]":"45.1","Single Cell Type RNA - NK-cells [nTPM]":"71.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.8","Single Cell Type RNA - Paneth cells [nTPM]":"29.0","Single Cell Type RNA - Peritubular cells [nTPM]":"36.9","Single Cell Type RNA - Plasma cells [nTPM]":"44.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"43.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.0","Single Cell Type RNA - Spermatocytes [nTPM]":"58.3","Single Cell Type RNA - Spermatogonia [nTPM]":"53.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"55.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.4","Single Cell Type RNA - T-cells [nTPM]":"66.6","Single Cell Type RNA - Theca cells [nTPM]":"62.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.1","Single Cell Type RNA - Urothelial cells [nTPM]":"48.7"},{"Gene":"RET","Gene synonym":["CDHF12","CDHR16","HSCR1","MEN2A","MEN2B","MTC1","PTC","RET51"],"Ensembl":"ENSG00000165731","Gene description":"Ret proto-oncogene","Uniprot":["P07949"],"Chromosome":"10","Position":"43077064-43130351","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Hirschsprung disease","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"20.8","brain":"27.3","parathyroid gland":"31.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Horizontal cells":"79.1","Ionocytes":"26.4","Skeletal myocytes":"23.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"11.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"74.6","NB-4":"42.2","SH-SY5Y":"329.3","THP-1":"95.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"53.3","spinal cord":"19.4"},"Antibody":["CAB002581","HPA008356","HPA008495"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB002581":"AB_563673","HPA008356":"AB_1847232","HPA008495":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.02e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"20.8","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"5.5","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"3.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"14.4","Tissue RNA - midbrain [nTPM]":"27.3","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"31.8","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"7.6","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"1.7","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"7.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"74.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"42.2","Cell RNA - NTERA-2 [nTPM]":"7.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"329.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"4.1","Cell RNA - THP-1 [nTPM]":"95.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"5.5","Brain RNA - medulla oblongata [nTPM]":"14.4","Brain RNA - midbrain [nTPM]":"27.3","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"7.6","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"79.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"RETREG1","Gene synonym":["FAM134B","FLJ20152","JK1"],"Ensembl":"ENSG00000154153","Gene description":"Reticulophagy regulator 1","Uniprot":["Q9H6L5"],"Chromosome":"5","Position":"16473038-16617038","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"91.4","skeletal muscle":"141.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"73.7","Cytotrophoblasts":"53.7","Exocrine glandular cells":"59.3","Glandular and luminal cells":"197.7","Pancreatic endocrine cells":"51.5","Proximal tubular cells":"152.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"28.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.3","T-cells":"1.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"26.0","GAMG":"20.3","HSkMC":"28.8","MOLT-4":"20.4","RPTEC TERT1":"26.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012077"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA012077":"AB_2668621"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"20.6","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"26.4","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"23.9","Tissue RNA - cerebral cortex [nTPM]":"33.2","Tissue RNA - cervix [nTPM]":"13.2","Tissue RNA - choroid plexus [nTPM]":"21.6","Tissue RNA - colon [nTPM]":"24.6","Tissue RNA - duodenum [nTPM]":"12.6","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"3.6","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"13.4","Tissue RNA - heart muscle [nTPM]":"91.4","Tissue RNA - hippocampal formation [nTPM]":"19.4","Tissue RNA - hypothalamus [nTPM]":"22.1","Tissue RNA - kidney [nTPM]":"61.0","Tissue RNA - liver [nTPM]":"44.2","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"27.2","Tissue RNA - midbrain [nTPM]":"25.2","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"37.7","Tissue RNA - parathyroid gland [nTPM]":"30.1","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"27.8","Tissue RNA - prostate [nTPM]":"11.1","Tissue RNA - rectum [nTPM]":"32.4","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"141.8","Tissue RNA - skin 1 [nTPM]":"10.0","Tissue RNA - small intestine [nTPM]":"25.6","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"23.6","Tissue RNA - spleen [nTPM]":"2.3","Tissue RNA - stomach 1 [nTPM]":"10.9","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"25.0","Tissue RNA - thymus [nTPM]":"20.6","Tissue RNA - thyroid gland [nTPM]":"6.7","Tissue RNA - tongue [nTPM]":"81.9","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"37.6","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"3.5","Cell RNA - ASC diff [nTPM]":"26.0","Cell RNA - ASC TERT1 [nTPM]":"3.2","Cell RNA - BEWO [nTPM]":"15.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"2.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"2.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"20.3","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"7.8","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"4.1","Cell RNA - HEK 293 [nTPM]":"3.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"5.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"28.8","Cell RNA - hTCEpi [nTPM]":"11.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"3.1","Cell RNA - hTERT-RPE1 [nTPM]":"7.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"15.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"20.4","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"3.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.2","Cell RNA - RPTEC TERT1 [nTPM]":"26.2","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"17.4","Cell RNA - SH-SY5Y [nTPM]":"2.0","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"13.1","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"5.9","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"6.4","Cell RNA - U-251 MG [nTPM]":"3.1","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"14.9","Cell RNA - U-937 [nTPM]":"18.0","Cell RNA - WM-115 [nTPM]":"6.5","Blood RNA - basophil [nTPM]":"2.3","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"20.6","Brain RNA - basal ganglia [nTPM]":"26.4","Brain RNA - cerebellum [nTPM]":"23.9","Brain RNA - cerebral cortex [nTPM]":"33.2","Brain RNA - hippocampal formation [nTPM]":"19.4","Brain RNA - hypothalamus [nTPM]":"22.1","Brain RNA - medulla oblongata [nTPM]":"27.2","Brain RNA - midbrain [nTPM]":"25.2","Brain RNA - pons [nTPM]":"27.8","Brain RNA - spinal cord [nTPM]":"23.6","Brain RNA - thalamus [nTPM]":"25.0","Brain RNA - white matter [nTPM]":"37.6","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"9.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.7","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"31.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"45.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.0","Single Cell Type RNA - Fibroblasts [nTPM]":"7.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"197.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"152.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"8.1","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RFC1","Gene synonym":["A1","MHCBFB","PO-GA","RFC140"],"Ensembl":"ENSG00000035928","Gene description":"Replication factor C subunit 1","Uniprot":["P35251"],"Chromosome":"4","Position":"39287456-39366375","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA replication","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009520","HPA046116","HPA069306"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB009520":"AB_2178317","HPA046116":"AB_2679544","HPA069306":"AB_2686115"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.43e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"19.0","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"16.7","Tissue RNA - basal ganglia [nTPM]":"19.2","Tissue RNA - bone marrow [nTPM]":"33.1","Tissue RNA - breast [nTPM]":"22.2","Tissue RNA - cerebellum [nTPM]":"15.4","Tissue RNA - cerebral cortex [nTPM]":"15.6","Tissue RNA - cervix [nTPM]":"16.9","Tissue RNA - choroid plexus [nTPM]":"12.0","Tissue RNA - colon [nTPM]":"15.3","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"19.2","Tissue RNA - epididymis [nTPM]":"17.4","Tissue RNA - esophagus [nTPM]":"13.8","Tissue RNA - fallopian tube [nTPM]":"14.6","Tissue RNA - gallbladder [nTPM]":"12.2","Tissue RNA - heart muscle [nTPM]":"16.5","Tissue RNA - hippocampal formation [nTPM]":"13.5","Tissue RNA - hypothalamus [nTPM]":"14.9","Tissue RNA - kidney [nTPM]":"20.8","Tissue RNA - liver [nTPM]":"25.5","Tissue RNA - lung [nTPM]":"18.2","Tissue RNA - lymph node [nTPM]":"30.2","Tissue RNA - medulla oblongata [nTPM]":"16.5","Tissue RNA - midbrain [nTPM]":"15.6","Tissue RNA - ovary [nTPM]":"26.1","Tissue RNA - pancreas [nTPM]":"29.0","Tissue RNA - parathyroid gland [nTPM]":"31.4","Tissue RNA - pituitary gland [nTPM]":"14.7","Tissue RNA - placenta [nTPM]":"14.6","Tissue RNA - pons [nTPM]":"18.0","Tissue RNA - prostate [nTPM]":"17.8","Tissue RNA - rectum [nTPM]":"14.8","Tissue RNA - retina [nTPM]":"24.3","Tissue RNA - salivary gland [nTPM]":"16.6","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"11.6","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"17.1","Tissue RNA - spinal cord [nTPM]":"15.4","Tissue RNA - spleen [nTPM]":"17.0","Tissue RNA - stomach 1 [nTPM]":"14.9","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"14.8","Tissue RNA - thymus [nTPM]":"28.0","Tissue RNA - thyroid gland [nTPM]":"23.1","Tissue RNA - tongue [nTPM]":"15.9","Tissue RNA - tonsil [nTPM]":"30.2","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"14.1","Tissue RNA - white matter [nTPM]":"25.5","Cell RNA - A-431 [nTPM]":"43.5","Cell RNA - A549 [nTPM]":"19.4","Cell RNA - AF22 [nTPM]":"53.7","Cell RNA - AN3-CA [nTPM]":"44.1","Cell RNA - ASC diff [nTPM]":"25.4","Cell RNA - ASC TERT1 [nTPM]":"32.0","Cell RNA - BEWO [nTPM]":"27.5","Cell RNA - BJ [nTPM]":"49.1","Cell RNA - BJ hTERT+ [nTPM]":"44.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.2","Cell RNA - CACO-2 [nTPM]":"37.8","Cell RNA - CAPAN-2 [nTPM]":"43.1","Cell RNA - Daudi [nTPM]":"106.5","Cell RNA - EFO-21 [nTPM]":"32.4","Cell RNA - fHDF\/TERT166 [nTPM]":"33.2","Cell RNA - GAMG [nTPM]":"52.8","Cell RNA - HaCaT [nTPM]":"20.7","Cell RNA - HAP1 [nTPM]":"49.8","Cell RNA - HBEC3-KT [nTPM]":"42.6","Cell RNA - HBF TERT88 [nTPM]":"78.5","Cell RNA - HDLM-2 [nTPM]":"19.5","Cell RNA - HEK 293 [nTPM]":"33.9","Cell RNA - HEL [nTPM]":"48.0","Cell RNA - HeLa [nTPM]":"35.6","Cell RNA - Hep G2 [nTPM]":"34.7","Cell RNA - HHSteC [nTPM]":"30.6","Cell RNA - HL-60 [nTPM]":"67.5","Cell RNA - HMC-1 [nTPM]":"30.7","Cell RNA - HSkMC [nTPM]":"24.6","Cell RNA - hTCEpi [nTPM]":"33.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.9","Cell RNA - hTERT-HME1 [nTPM]":"55.3","Cell RNA - hTERT-RPE1 [nTPM]":"39.1","Cell RNA - HUVEC TERT2 [nTPM]":"38.8","Cell RNA - JURKAT [nTPM]":"52.1","Cell RNA - K-562 [nTPM]":"48.0","Cell RNA - Karpas-707 [nTPM]":"22.1","Cell RNA - LHCN-M2 [nTPM]":"37.9","Cell RNA - MCF7 [nTPM]":"17.5","Cell RNA - MOLT-4 [nTPM]":"99.7","Cell RNA - NB-4 [nTPM]":"43.4","Cell RNA - NTERA-2 [nTPM]":"33.0","Cell RNA - OE19 [nTPM]":"26.8","Cell RNA - PC-3 [nTPM]":"24.2","Cell RNA - REH [nTPM]":"78.1","Cell RNA - RH-30 [nTPM]":"97.8","Cell RNA - RPMI-8226 [nTPM]":"33.7","Cell RNA - RPTEC TERT1 [nTPM]":"21.4","Cell RNA - RT4 [nTPM]":"30.1","Cell RNA - SCLC-21H [nTPM]":"37.6","Cell RNA - SH-SY5Y [nTPM]":"36.4","Cell RNA - SiHa [nTPM]":"29.1","Cell RNA - SK-BR-3 [nTPM]":"11.3","Cell RNA - SK-MEL-30 [nTPM]":"37.6","Cell RNA - SuSa [nTPM]":"33.4","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"37.5","Cell RNA - TIME [nTPM]":"30.0","Cell RNA - U-138 MG [nTPM]":"40.3","Cell RNA - U-2 OS [nTPM]":"49.6","Cell RNA - U-2197 [nTPM]":"37.8","Cell RNA - U-251 MG [nTPM]":"63.1","Cell RNA - U-266\/70 [nTPM]":"31.0","Cell RNA - U-266\/84 [nTPM]":"45.8","Cell RNA - U-698 [nTPM]":"101.3","Cell RNA - U-87 MG [nTPM]":"33.1","Cell RNA - U-937 [nTPM]":"69.3","Cell RNA - WM-115 [nTPM]":"41.2","Blood RNA - basophil [nTPM]":"8.2","Blood RNA - classical monocyte [nTPM]":"8.6","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"13.7","Blood RNA - intermediate monocyte [nTPM]":"6.9","Blood RNA - MAIT T-cell [nTPM]":"10.1","Blood RNA - memory B-cell [nTPM]":"14.6","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"11.9","Blood RNA - myeloid DC [nTPM]":"6.9","Blood RNA - naive B-cell [nTPM]":"16.1","Blood RNA - naive CD4 T-cell [nTPM]":"13.8","Blood RNA - naive CD8 T-cell [nTPM]":"12.2","Blood RNA - neutrophil [nTPM]":"3.9","Blood RNA - NK-cell [nTPM]":"12.6","Blood RNA - non-classical monocyte [nTPM]":"8.9","Blood RNA - plasmacytoid DC [nTPM]":"14.3","Blood RNA - T-reg [nTPM]":"11.5","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"19.2","Brain RNA - cerebellum [nTPM]":"15.4","Brain RNA - cerebral cortex [nTPM]":"15.6","Brain RNA - hippocampal formation [nTPM]":"13.5","Brain RNA - hypothalamus [nTPM]":"14.9","Brain RNA - medulla oblongata [nTPM]":"16.5","Brain RNA - midbrain [nTPM]":"15.6","Brain RNA - pons [nTPM]":"18.0","Brain RNA - spinal cord [nTPM]":"15.4","Brain RNA - thalamus [nTPM]":"14.8","Brain RNA - white matter [nTPM]":"25.5","Single Cell Type RNA - Adipocytes [nTPM]":"65.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"120.6","Single Cell Type RNA - Astrocytes [nTPM]":"33.0","Single Cell Type RNA - B-cells [nTPM]":"62.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Bipolar cells [nTPM]":"67.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"60.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"62.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"86.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"37.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"57.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.1","Single Cell Type RNA - dendritic cells [nTPM]":"83.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"72.4","Single Cell Type RNA - Ductal cells [nTPM]":"54.8","Single Cell Type RNA - Early spermatids [nTPM]":"73.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"79.1","Single Cell Type RNA - Endothelial cells [nTPM]":"56.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.0","Single Cell Type RNA - Erythroid cells [nTPM]":"57.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"66.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.5","Single Cell Type RNA - Fibroblasts [nTPM]":"54.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.0","Single Cell Type RNA - granulocytes [nTPM]":"25.9","Single Cell Type RNA - Granulosa cells [nTPM]":"82.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"57.8","Single Cell Type RNA - Hepatocytes [nTPM]":"82.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.7","Single Cell Type RNA - Horizontal cells [nTPM]":"85.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"58.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"44.3","Single Cell Type RNA - Langerhans cells [nTPM]":"16.6","Single Cell Type RNA - Late spermatids [nTPM]":"32.3","Single Cell Type RNA - Leydig cells [nTPM]":"82.0","Single Cell Type RNA - Macrophages [nTPM]":"35.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"58.1","Single Cell Type RNA - Muller glia cells [nTPM]":"82.7","Single Cell Type RNA - NK-cells [nTPM]":"107.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.1","Single Cell Type RNA - Paneth cells [nTPM]":"34.2","Single Cell Type RNA - Peritubular cells [nTPM]":"91.7","Single Cell Type RNA - Plasma cells [nTPM]":"75.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"124.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"83.3","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"61.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"54.6","Single Cell Type RNA - Spermatocytes [nTPM]":"49.0","Single Cell Type RNA - Spermatogonia [nTPM]":"66.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.2","Single Cell Type RNA - T-cells [nTPM]":"63.7","Single Cell Type RNA - Theca cells [nTPM]":"70.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.1","Single Cell Type RNA - Urothelial cells [nTPM]":"44.5"},{"Gene":"RGR","Gene synonym":["RP44"],"Ensembl":"ENSG00000148604","Gene description":"Retinal G protein coupled receptor","Uniprot":["P47804"],"Chromosome":"10","Position":"84230666-84259960","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"retina":"139.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"29","RNA single cell type specific nTPM":{"Muller glia cells":"1475.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"midbrain":"23.4","olfactory bulb":"49.7","thalamus":"27.3"},"Antibody":["HPA059149"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA059149":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"11.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"14.4","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"139.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"11.9","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"20.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1475.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RGS9","Gene synonym":["MGC111763","MGC26458","PERRS","RGS9L"],"Ensembl":"ENSG00000108370","Gene description":"Regulator of G protein signaling 9","Uniprot":["O75916"],"Chromosome":"17","Position":"65100812-65227703","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Signal transduction inhibitor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"23.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"325.2","Rod photoreceptor cells":"480.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"gdT-cell":"9.7","MAIT T-cell":"2.5","memory CD8 T-cell":"6.8","naive CD8 T-cell":"3.2","NK-cell":"4.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"42","RNA blood lineage specific nTPM":{"NK-cells":"4.0","T-cells":"9.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"25.9","HEL":"11.7","hTERT-RPE1":"4.7","SuSa":"4.1"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"basal ganglia":"248.1"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"10","RNA pig brain regional specific nTPM":{"basal ganglia":"110.0"},"Antibody":["HPA013550","HPA014137"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA013550":null,"HPA014137":"AB_2668943"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"23.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"4.3","Tissue RNA - cerebral cortex [nTPM]":"9.4","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"8.5","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"5.1","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"2.3","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"5.9","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"5.5","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"3.8","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"7.4","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"2.9","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"1.2","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"25.9","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"11.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"4.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.6","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"4.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"9.7","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"4.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"23.5","Brain RNA - cerebellum [nTPM]":"4.3","Brain RNA - cerebral cortex [nTPM]":"9.4","Brain RNA - hippocampal formation [nTPM]":"5.1","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"5.9","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"7.4","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"33.3","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"25.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"325.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"27.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.8","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"59.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"19.4","Single Cell Type RNA - Muller glia cells [nTPM]":"39.2","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"6.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"480.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"10.3","Single Cell Type RNA - Theca cells [nTPM]":"12.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"RGS9BP","Gene synonym":["FLJ45744","PERRS","R9AP"],"Ensembl":"ENSG00000186326","Gene description":"Regulator of G protein signaling 9 binding protein","Uniprot":["Q6ZS82"],"Chromosome":"19","Position":"32675848-32678300","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Signal transduction inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"choroid plexus":"28.9","retina":"17.4","skeletal muscle":"9.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"29.0","Cone photoreceptor cells":"56.3","Rod photoreceptor cells":"75.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"6.3","HMC-1":"1.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049791"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA049791":"AB_2680884"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"28.9","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"17.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"9.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"1.5","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"6.3","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"1.5","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"29.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"75.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RHO","Gene synonym":["CSNBAD1","OPN2","RP4"],"Ensembl":"ENSG00000163914","Gene description":"Rhodopsin","Uniprot":["P08100"],"Chromosome":"3","Position":"129528639-129535344","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Congenital stationary night blindness","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5994","RNA tissue specific nTPM":{"retina":"4062.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"4509.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hippocampal formation":"9.7"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"1.1"},"Antibody":["HPA013440","CAB022486","CAB034887","CAB034888"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022486":null,"CAB034887":"AB_785511","CAB034888":"AB_785512","HPA013440":"AB_2668844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"4062.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"369.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"454.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"26.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"218.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"590.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4509.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RHOBTB2","Gene synonym":["DBC2","KIAA0717"],"Ensembl":"ENSG00000008853","Gene description":"Rho related BTB domain containing 2","Uniprot":["Q9BYZ6"],"Chromosome":"8","Position":"22987417-23020199","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"50.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"64.1","Alveolar cells type 2":"77.7","Excitatory neurons":"33.3","Proximal enterocytes":"57.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"85.7","hTCEpi":"73.6","RT4":"126.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060938"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA060938":"AB_2684391"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.98e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.5","Tissue RNA - adrenal gland [nTPM]":"8.8","Tissue RNA - amygdala [nTPM]":"17.9","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"31.7","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"8.4","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"27.6","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"6.2","Tissue RNA - duodenum [nTPM]":"8.5","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"9.8","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"21.8","Tissue RNA - hippocampal formation [nTPM]":"21.4","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"11.2","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"50.5","Tissue RNA - lymph node [nTPM]":"14.9","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"10.3","Tissue RNA - ovary [nTPM]":"25.8","Tissue RNA - pancreas [nTPM]":"8.0","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"14.2","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"5.6","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"23.0","Tissue RNA - skeletal muscle [nTPM]":"16.5","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"21.2","Tissue RNA - smooth muscle [nTPM]":"6.5","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"12.6","Tissue RNA - stomach 1 [nTPM]":"8.3","Tissue RNA - testis [nTPM]":"8.1","Tissue RNA - thalamus [nTPM]":"22.8","Tissue RNA - thymus [nTPM]":"8.9","Tissue RNA - thyroid gland [nTPM]":"18.5","Tissue RNA - tongue [nTPM]":"13.6","Tissue RNA - tonsil [nTPM]":"16.7","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"4.5","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"6.8","Cell RNA - A549 [nTPM]":"13.2","Cell RNA - AF22 [nTPM]":"10.4","Cell RNA - AN3-CA [nTPM]":"16.7","Cell RNA - ASC diff [nTPM]":"12.4","Cell RNA - ASC TERT1 [nTPM]":"8.7","Cell RNA - BEWO [nTPM]":"14.0","Cell RNA - BJ [nTPM]":"9.2","Cell RNA - BJ hTERT+ [nTPM]":"12.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.7","Cell RNA - CACO-2 [nTPM]":"34.2","Cell RNA - CAPAN-2 [nTPM]":"6.6","Cell RNA - Daudi [nTPM]":"85.7","Cell RNA - EFO-21 [nTPM]":"13.8","Cell RNA - fHDF\/TERT166 [nTPM]":"13.3","Cell RNA - GAMG [nTPM]":"18.5","Cell RNA - HaCaT [nTPM]":"13.2","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"51.5","Cell RNA - HBF TERT88 [nTPM]":"6.8","Cell RNA - HDLM-2 [nTPM]":"7.4","Cell RNA - HEK 293 [nTPM]":"3.0","Cell RNA - HEL [nTPM]":"9.3","Cell RNA - HeLa [nTPM]":"17.8","Cell RNA - Hep G2 [nTPM]":"9.7","Cell RNA - HHSteC [nTPM]":"6.0","Cell RNA - HL-60 [nTPM]":"5.5","Cell RNA - HMC-1 [nTPM]":"18.5","Cell RNA - HSkMC [nTPM]":"11.3","Cell RNA - hTCEpi [nTPM]":"73.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.8","Cell RNA - hTERT-HME1 [nTPM]":"7.4","Cell RNA - hTERT-RPE1 [nTPM]":"9.8","Cell RNA - HUVEC TERT2 [nTPM]":"10.4","Cell RNA - JURKAT [nTPM]":"6.1","Cell RNA - K-562 [nTPM]":"2.3","Cell RNA - Karpas-707 [nTPM]":"8.2","Cell RNA - LHCN-M2 [nTPM]":"9.5","Cell RNA - MCF7 [nTPM]":"19.7","Cell RNA - MOLT-4 [nTPM]":"3.5","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"11.0","Cell RNA - OE19 [nTPM]":"19.7","Cell RNA - PC-3 [nTPM]":"9.2","Cell RNA - REH [nTPM]":"4.7","Cell RNA - RH-30 [nTPM]":"16.8","Cell RNA - RPMI-8226 [nTPM]":"5.9","Cell RNA - RPTEC TERT1 [nTPM]":"10.1","Cell RNA - RT4 [nTPM]":"126.9","Cell RNA - SCLC-21H [nTPM]":"6.8","Cell RNA - SH-SY5Y [nTPM]":"12.5","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"21.2","Cell RNA - SK-MEL-30 [nTPM]":"14.5","Cell RNA - SuSa [nTPM]":"7.7","Cell RNA - T-47d [nTPM]":"4.0","Cell RNA - THP-1 [nTPM]":"14.0","Cell RNA - TIME [nTPM]":"12.8","Cell RNA - U-138 MG [nTPM]":"17.7","Cell RNA - U-2 OS [nTPM]":"12.8","Cell RNA - U-2197 [nTPM]":"32.0","Cell RNA - U-251 MG [nTPM]":"10.6","Cell RNA - U-266\/70 [nTPM]":"20.7","Cell RNA - U-266\/84 [nTPM]":"21.5","Cell RNA - U-698 [nTPM]":"30.2","Cell RNA - U-87 MG [nTPM]":"17.2","Cell RNA - U-937 [nTPM]":"7.9","Cell RNA - WM-115 [nTPM]":"14.0","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"5.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"4.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"17.9","Brain RNA - basal ganglia [nTPM]":"31.7","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"27.6","Brain RNA - hippocampal formation [nTPM]":"21.4","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"10.3","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"22.8","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"4.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"77.7","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"7.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"31.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"9.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.7","Single Cell Type RNA - dendritic cells [nTPM]":"4.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.5","Single Cell Type RNA - Fibroblasts [nTPM]":"5.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.3","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"3.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"1.5","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"57.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"RIMS1","Gene synonym":["CORD7","KIAA0340","RAB3IP2","RIM","RIM1"],"Ensembl":"ENSG00000079841","Gene description":"Regulating synaptic membrane exocytosis 1","Uniprot":["Q86UR5"],"Chromosome":"6","Position":"71886703-72403143","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Differentiation","Exocytosis","Neurotransmitter transport","Sensory transduction","Transport","Vision"],"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"49","RNA tissue specific nTPM":{"brain":"365.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"653.2","Inhibitory neurons":"572.7","Oligodendrocyte precursor cells":"323.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"0.7"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"16","RNA brain regional specific nTPM":{"cerebellum":"365.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"5.2","EFO-21":"8.8","LHCN-M2":"10.0","RPTEC TERT1":"15.0","SH-SY5Y":"10.7","TIME":"5.4","U-138 MG":"5.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"352.9"},"Antibody":["HPA076565"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA076565":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"365.0","Tissue RNA - cerebral cortex [nTPM]":"22.5","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"16.3","Tissue RNA - hypothalamus [nTPM]":"8.4","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"9.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"20.8","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"13.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"5.2","Cell RNA - EFO-21 [nTPM]":"8.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.0","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"1.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"10.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"10.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"5.4","Cell RNA - U-138 MG [nTPM]":"5.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"365.0","Brain RNA - cerebral cortex [nTPM]":"22.5","Brain RNA - hippocampal formation [nTPM]":"16.3","Brain RNA - hypothalamus [nTPM]":"8.4","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"9.0","Brain RNA - pons [nTPM]":"20.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"13.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"120.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"69.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"15.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"653.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"572.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"109.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"323.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"76.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.7","Single Cell Type RNA - Spermatocytes [nTPM]":"21.3","Single Cell Type RNA - Spermatogonia [nTPM]":"13.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"RIMS2","Gene synonym":["KIAA0751","OBOE","RAB3IP3","RIM2"],"Ensembl":"ENSG00000176406","Gene description":"Regulating synaptic membrane exocytosis 2","Uniprot":["Q9UQ26"],"Chromosome":"8","Position":"103500696-104256094","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"50.6","brain":"48.2","retina":"102.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"383.6","Cone photoreceptor cells":"706.8","Excitatory neurons":"1589.3","Inhibitory neurons":"1234.9","Oligodendrocyte precursor cells":"577.0","Rod photoreceptor cells":"1088.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"9.2","RT4":"7.3","SCLC-21H":"16.5","SuSa":"8.8","U-2 OS":"6.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046538","HPA066498","CAB079049"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB079049":null,"HPA046538":null,"HPA066498":"AB_2685678"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"50.6","Tissue RNA - amygdala [nTPM]":"22.4","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"27.1","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"35.5","Tissue RNA - cerebral cortex [nTPM]":"48.2","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"5.9","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"18.4","Tissue RNA - hypothalamus [nTPM]":"16.4","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"9.7","Tissue RNA - ovary [nTPM]":"2.0","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"15.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"102.3","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"16.7","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"29.4","Cell RNA - A-431 [nTPM]":"4.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"9.2","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"1.4","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"1.9","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"16.5","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"8.8","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"6.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"22.4","Brain RNA - basal ganglia [nTPM]":"27.1","Brain RNA - cerebellum [nTPM]":"35.5","Brain RNA - cerebral cortex [nTPM]":"48.2","Brain RNA - hippocampal formation [nTPM]":"18.4","Brain RNA - hypothalamus [nTPM]":"16.4","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"9.7","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"16.7","Brain RNA - white matter [nTPM]":"29.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.5","Single Cell Type RNA - Astrocytes [nTPM]":"38.5","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"383.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"16.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"706.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"34.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1589.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"3.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.7","Single Cell Type RNA - granulocytes [nTPM]":"16.4","Single Cell Type RNA - Granulosa cells [nTPM]":"18.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1234.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"20.1","Single Cell Type RNA - Leydig cells [nTPM]":"72.1","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"63.7","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"86.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"577.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1088.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"34.8","Single Cell Type RNA - Spermatogonia [nTPM]":"15.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"RIPOR2","Gene synonym":["C6orf32","DIFF48","FAM65B","KIAA0386","MYONAP"],"Ensembl":"ENSG00000111913","Gene description":"RHO family interacting cell polarization regulator 2","Uniprot":["Q9Y4F9"],"Chromosome":"6","Position":"24804282-25042170","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell adhesion","Chemotaxis","Differentiation","Hearing","Myogenesis"],"Molecular function":["Developmental protein","Signal transduction inhibitor"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"82.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"57.4","dendritic cells":"98.4","Respiratory ciliated cells":"83.1","Syncytiotrophoblasts":"82.8","T-cells":"38.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"951.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"951.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"30.9","Daudi":"73.5","fHDF\/TERT166":"73.2","U-266\/70":"25.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.1","Tissue RNA - adrenal gland [nTPM]":"3.7","Tissue RNA - amygdala [nTPM]":"15.9","Tissue RNA - appendix [nTPM]":"49.1","Tissue RNA - basal ganglia [nTPM]":"22.4","Tissue RNA - bone marrow [nTPM]":"27.6","Tissue RNA - breast [nTPM]":"6.1","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"16.7","Tissue RNA - cervix [nTPM]":"13.5","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"46.3","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"14.8","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"3.1","Tissue RNA - hippocampal formation [nTPM]":"14.0","Tissue RNA - hypothalamus [nTPM]":"9.1","Tissue RNA - kidney [nTPM]":"3.0","Tissue RNA - liver [nTPM]":"4.3","Tissue RNA - lung [nTPM]":"20.7","Tissue RNA - lymph node [nTPM]":"82.6","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"9.5","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"13.0","Tissue RNA - placenta [nTPM]":"6.0","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"3.8","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"8.2","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"19.5","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"17.5","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"4.6","Tissue RNA - spleen [nTPM]":"55.9","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"6.4","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"41.0","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"71.0","Tissue RNA - urinary bladder [nTPM]":"10.2","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"30.9","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"11.3","Cell RNA - BJ [nTPM]":"8.8","Cell RNA - BJ hTERT+ [nTPM]":"15.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.4","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"73.5","Cell RNA - EFO-21 [nTPM]":"2.0","Cell RNA - fHDF\/TERT166 [nTPM]":"73.2","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"7.3","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"17.8","Cell RNA - HeLa [nTPM]":"1.2","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"3.2","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.2","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"12.2","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"17.0","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"18.5","Cell RNA - RH-30 [nTPM]":"3.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"5.7","Cell RNA - SuSa [nTPM]":"10.3","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"25.4","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"414.0","Blood RNA - classical monocyte [nTPM]":"100.8","Blood RNA - eosinophil [nTPM]":"334.5","Blood RNA - gdT-cell [nTPM]":"128.6","Blood RNA - intermediate monocyte [nTPM]":"127.3","Blood RNA - MAIT T-cell [nTPM]":"134.8","Blood RNA - memory B-cell [nTPM]":"188.3","Blood RNA - memory CD4 T-cell [nTPM]":"131.8","Blood RNA - memory CD8 T-cell [nTPM]":"136.6","Blood RNA - myeloid DC [nTPM]":"68.7","Blood RNA - naive B-cell [nTPM]":"176.3","Blood RNA - naive CD4 T-cell [nTPM]":"171.6","Blood RNA - naive CD8 T-cell [nTPM]":"136.8","Blood RNA - neutrophil [nTPM]":"951.9","Blood RNA - NK-cell [nTPM]":"125.7","Blood RNA - non-classical monocyte [nTPM]":"173.8","Blood RNA - plasmacytoid DC [nTPM]":"57.7","Blood RNA - T-reg [nTPM]":"124.9","Blood RNA - total PBMC [nTPM]":"168.1","Brain RNA - amygdala [nTPM]":"15.9","Brain RNA - basal ganglia [nTPM]":"22.4","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"16.7","Brain RNA - hippocampal formation [nTPM]":"14.0","Brain RNA - hypothalamus [nTPM]":"9.1","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"9.5","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"4.6","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"57.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"18.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"98.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"12.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"25.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"15.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"83.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"82.8","Single Cell Type RNA - T-cells [nTPM]":"38.0","Single Cell Type RNA - Theca cells [nTPM]":"1.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RLBP1","Gene synonym":["CRALBP"],"Ensembl":"ENSG00000140522","Gene description":"Retinaldehyde binding protein 1","Uniprot":["P12271"],"Chromosome":"15","Position":"89209869-89221614","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Transport","Vision"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"retina":"265.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"34","RNA single cell type specific nTPM":{"Muller glia cells":"3148.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"30","RNA cancer specific FPKM":{"glioma":"3.7","melanoma":"7.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"53","RNA cell line specific nTPM":{"SK-MEL-30":"22.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042051","HPA044083"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Centrosome"],"Antibody RRID":{"HPA042051":"AB_2732495","HPA044083":"AB_2678802"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"14.9","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"16.9","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"15.0","Tissue RNA - cerebral cortex [nTPM]":"20.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"16.7","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"15.7","Tissue RNA - hypothalamus [nTPM]":"14.5","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"14.5","Tissue RNA - midbrain [nTPM]":"14.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"14.3","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"265.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"14.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"14.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"22.3","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"14.9","Brain RNA - basal ganglia [nTPM]":"16.9","Brain RNA - cerebellum [nTPM]":"15.0","Brain RNA - cerebral cortex [nTPM]":"20.8","Brain RNA - hippocampal formation [nTPM]":"15.7","Brain RNA - hypothalamus [nTPM]":"14.5","Brain RNA - medulla oblongata [nTPM]":"14.5","Brain RNA - midbrain [nTPM]":"14.2","Brain RNA - pons [nTPM]":"14.3","Brain RNA - spinal cord [nTPM]":"14.0","Brain RNA - thalamus [nTPM]":"14.9","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"21.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3148.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"90.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RNASET2","Gene synonym":["bA514O12.3","FLJ10907","RNASE6PL"],"Ensembl":"ENSG00000026297","Gene description":"Ribonuclease T2","Uniprot":["O00584"],"Chromosome":"6","Position":"166922113-166957191","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Endonuclease","Hydrolase","Lyase","Nuclease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"490.2","Glandular and luminal cells":"761.3","Hofbauer cells":"382.2","Kupffer cells":"484.7","Macrophages":"418.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"THP-1":"497.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029013","HPA066509"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029013":"AB_10602922","HPA066509":"AB_2685682"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"34.9","Tissue RNA - adrenal gland [nTPM]":"35.0","Tissue RNA - amygdala [nTPM]":"50.1","Tissue RNA - appendix [nTPM]":"68.6","Tissue RNA - basal ganglia [nTPM]":"50.4","Tissue RNA - bone marrow [nTPM]":"124.3","Tissue RNA - breast [nTPM]":"50.2","Tissue RNA - cerebellum [nTPM]":"52.2","Tissue RNA - cerebral cortex [nTPM]":"65.9","Tissue RNA - cervix [nTPM]":"161.5","Tissue RNA - choroid plexus [nTPM]":"52.3","Tissue RNA - colon [nTPM]":"74.0","Tissue RNA - duodenum [nTPM]":"57.6","Tissue RNA - endometrium 1 [nTPM]":"49.1","Tissue RNA - epididymis [nTPM]":"140.7","Tissue RNA - esophagus [nTPM]":"24.8","Tissue RNA - fallopian tube [nTPM]":"134.6","Tissue RNA - gallbladder [nTPM]":"69.6","Tissue RNA - heart muscle [nTPM]":"19.8","Tissue RNA - hippocampal formation [nTPM]":"49.5","Tissue RNA - hypothalamus [nTPM]":"53.5","Tissue RNA - kidney [nTPM]":"31.2","Tissue RNA - liver [nTPM]":"52.4","Tissue RNA - lung [nTPM]":"47.2","Tissue RNA - lymph node [nTPM]":"117.4","Tissue RNA - medulla oblongata [nTPM]":"68.2","Tissue RNA - midbrain [nTPM]":"54.3","Tissue RNA - ovary [nTPM]":"36.2","Tissue RNA - pancreas [nTPM]":"144.7","Tissue RNA - parathyroid gland [nTPM]":"40.7","Tissue RNA - pituitary gland [nTPM]":"26.3","Tissue RNA - placenta [nTPM]":"43.5","Tissue RNA - pons [nTPM]":"66.2","Tissue RNA - prostate [nTPM]":"51.9","Tissue RNA - rectum [nTPM]":"89.9","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"112.8","Tissue RNA - seminal vesicle [nTPM]":"94.1","Tissue RNA - skeletal muscle [nTPM]":"7.3","Tissue RNA - skin 1 [nTPM]":"25.4","Tissue RNA - small intestine [nTPM]":"65.4","Tissue RNA - smooth muscle [nTPM]":"27.8","Tissue RNA - spinal cord [nTPM]":"61.9","Tissue RNA - spleen [nTPM]":"195.1","Tissue RNA - stomach 1 [nTPM]":"72.9","Tissue RNA - testis [nTPM]":"13.3","Tissue RNA - thalamus [nTPM]":"59.1","Tissue RNA - thymus [nTPM]":"43.8","Tissue RNA - thyroid gland [nTPM]":"76.7","Tissue RNA - tongue [nTPM]":"12.1","Tissue RNA - tonsil [nTPM]":"86.9","Tissue RNA - urinary bladder [nTPM]":"54.9","Tissue RNA - vagina [nTPM]":"32.2","Tissue RNA - white matter [nTPM]":"79.8","Cell RNA - A-431 [nTPM]":"12.8","Cell RNA - A549 [nTPM]":"14.2","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"37.8","Cell RNA - ASC diff [nTPM]":"57.0","Cell RNA - ASC TERT1 [nTPM]":"40.6","Cell RNA - BEWO [nTPM]":"8.4","Cell RNA - BJ [nTPM]":"15.8","Cell RNA - BJ hTERT+ [nTPM]":"21.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.4","Cell RNA - CACO-2 [nTPM]":"33.7","Cell RNA - CAPAN-2 [nTPM]":"19.9","Cell RNA - Daudi [nTPM]":"11.1","Cell RNA - EFO-21 [nTPM]":"149.8","Cell RNA - fHDF\/TERT166 [nTPM]":"41.3","Cell RNA - GAMG [nTPM]":"16.7","Cell RNA - HaCaT [nTPM]":"41.0","Cell RNA - HAP1 [nTPM]":"20.8","Cell RNA - HBEC3-KT [nTPM]":"18.6","Cell RNA - HBF TERT88 [nTPM]":"4.3","Cell RNA - HDLM-2 [nTPM]":"15.9","Cell RNA - HEK 293 [nTPM]":"35.1","Cell RNA - HEL [nTPM]":"10.2","Cell RNA - HeLa [nTPM]":"20.6","Cell RNA - Hep G2 [nTPM]":"84.6","Cell RNA - HHSteC [nTPM]":"19.1","Cell RNA - HL-60 [nTPM]":"152.7","Cell RNA - HMC-1 [nTPM]":"37.3","Cell RNA - HSkMC [nTPM]":"23.9","Cell RNA - hTCEpi [nTPM]":"33.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.3","Cell RNA - hTERT-HME1 [nTPM]":"2.7","Cell RNA - hTERT-RPE1 [nTPM]":"30.4","Cell RNA - HUVEC TERT2 [nTPM]":"10.1","Cell RNA - JURKAT [nTPM]":"21.7","Cell RNA - K-562 [nTPM]":"20.9","Cell RNA - Karpas-707 [nTPM]":"94.5","Cell RNA - LHCN-M2 [nTPM]":"10.9","Cell RNA - MCF7 [nTPM]":"44.9","Cell RNA - MOLT-4 [nTPM]":"12.6","Cell RNA - NB-4 [nTPM]":"109.5","Cell RNA - NTERA-2 [nTPM]":"6.4","Cell RNA - OE19 [nTPM]":"140.0","Cell RNA - PC-3 [nTPM]":"13.0","Cell RNA - REH [nTPM]":"25.0","Cell RNA - RH-30 [nTPM]":"16.6","Cell RNA - RPMI-8226 [nTPM]":"131.7","Cell RNA - RPTEC TERT1 [nTPM]":"136.3","Cell RNA - RT4 [nTPM]":"9.9","Cell RNA - SCLC-21H [nTPM]":"4.4","Cell RNA - SH-SY5Y [nTPM]":"28.7","Cell RNA - SiHa [nTPM]":"32.0","Cell RNA - SK-BR-3 [nTPM]":"100.4","Cell RNA - SK-MEL-30 [nTPM]":"8.3","Cell RNA - SuSa [nTPM]":"22.3","Cell RNA - T-47d [nTPM]":"13.1","Cell RNA - THP-1 [nTPM]":"497.9","Cell RNA - TIME [nTPM]":"19.3","Cell RNA - U-138 MG [nTPM]":"14.9","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"43.7","Cell RNA - U-251 MG [nTPM]":"13.5","Cell RNA - U-266\/70 [nTPM]":"15.0","Cell RNA - U-266\/84 [nTPM]":"19.5","Cell RNA - U-698 [nTPM]":"1.4","Cell RNA - U-87 MG [nTPM]":"32.3","Cell RNA - U-937 [nTPM]":"149.2","Cell RNA - WM-115 [nTPM]":"10.3","Blood RNA - basophil [nTPM]":"116.9","Blood RNA - classical monocyte [nTPM]":"185.6","Blood RNA - eosinophil [nTPM]":"674.8","Blood RNA - gdT-cell [nTPM]":"29.1","Blood RNA - intermediate monocyte [nTPM]":"277.0","Blood RNA - MAIT T-cell [nTPM]":"53.4","Blood RNA - memory B-cell [nTPM]":"136.7","Blood RNA - memory CD4 T-cell [nTPM]":"159.9","Blood RNA - memory CD8 T-cell [nTPM]":"72.3","Blood RNA - myeloid DC [nTPM]":"226.4","Blood RNA - naive B-cell [nTPM]":"119.6","Blood RNA - naive CD4 T-cell [nTPM]":"128.4","Blood RNA - naive CD8 T-cell [nTPM]":"41.4","Blood RNA - neutrophil [nTPM]":"438.9","Blood RNA - NK-cell [nTPM]":"30.7","Blood RNA - non-classical monocyte [nTPM]":"368.8","Blood RNA - plasmacytoid DC [nTPM]":"369.3","Blood RNA - T-reg [nTPM]":"90.8","Blood RNA - total PBMC [nTPM]":"179.8","Brain RNA - amygdala [nTPM]":"50.1","Brain RNA - basal ganglia [nTPM]":"50.4","Brain RNA - cerebellum [nTPM]":"52.2","Brain RNA - cerebral cortex [nTPM]":"65.9","Brain RNA - hippocampal formation [nTPM]":"49.5","Brain RNA - hypothalamus [nTPM]":"53.5","Brain RNA - medulla oblongata [nTPM]":"68.2","Brain RNA - midbrain [nTPM]":"54.3","Brain RNA - pons [nTPM]":"66.2","Brain RNA - spinal cord [nTPM]":"61.9","Brain RNA - thalamus [nTPM]":"59.1","Brain RNA - white matter [nTPM]":"79.8","Single Cell Type RNA - Adipocytes [nTPM]":"21.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"270.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"43.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"116.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"45.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"72.3","Single Cell Type RNA - Bipolar cells [nTPM]":"10.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"97.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"95.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"28.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.4","Single Cell Type RNA - dendritic cells [nTPM]":"286.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"133.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"59.2","Single Cell Type RNA - Early spermatids [nTPM]":"10.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"490.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"78.9","Single Cell Type RNA - Endothelial cells [nTPM]":"44.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"75.4","Single Cell Type RNA - Erythroid cells [nTPM]":"27.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.8","Single Cell Type RNA - Fibroblasts [nTPM]":"45.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"761.3","Single Cell Type RNA - granulocytes [nTPM]":"71.7","Single Cell Type RNA - Granulosa cells [nTPM]":"38.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"20.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"382.2","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"204.0","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"484.7","Single Cell Type RNA - Langerhans cells [nTPM]":"187.7","Single Cell Type RNA - Late spermatids [nTPM]":"11.3","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"418.2","Single Cell Type RNA - Melanocytes [nTPM]":"58.7","Single Cell Type RNA - Microglial cells [nTPM]":"113.4","Single Cell Type RNA - monocytes [nTPM]":"146.1","Single Cell Type RNA - Muller glia cells [nTPM]":"24.4","Single Cell Type RNA - NK-cells [nTPM]":"64.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"74.1","Single Cell Type RNA - Paneth cells [nTPM]":"324.8","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"158.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"178.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.0","Single Cell Type RNA - Spermatogonia [nTPM]":"23.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"58.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.8","Single Cell Type RNA - T-cells [nTPM]":"149.2","Single Cell Type RNA - Theca cells [nTPM]":"15.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"193.0","Single Cell Type RNA - Urothelial cells [nTPM]":"103.9"},{"Gene":"RNF13","Gene synonym":["RZF"],"Ensembl":"ENSG00000082996","Gene description":"Ring finger protein 13","Uniprot":["O43567"],"Chromosome":"3","Position":"149812770-149962139","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"591.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"462.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064784"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA064784":"AB_2685350"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.00e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Tissue RNA - adipose tissue [nTPM]":"48.2","Tissue RNA - adrenal gland [nTPM]":"41.2","Tissue RNA - amygdala [nTPM]":"58.1","Tissue RNA - appendix [nTPM]":"40.4","Tissue RNA - basal ganglia [nTPM]":"95.2","Tissue RNA - bone marrow [nTPM]":"19.9","Tissue RNA - breast [nTPM]":"53.9","Tissue RNA - cerebellum [nTPM]":"88.1","Tissue RNA - cerebral cortex [nTPM]":"91.5","Tissue RNA - cervix [nTPM]":"33.6","Tissue RNA - choroid plexus [nTPM]":"63.7","Tissue RNA - colon [nTPM]":"35.0","Tissue RNA - duodenum [nTPM]":"28.9","Tissue RNA - endometrium 1 [nTPM]":"33.3","Tissue RNA - epididymis [nTPM]":"57.2","Tissue RNA - esophagus [nTPM]":"32.6","Tissue RNA - fallopian tube [nTPM]":"30.2","Tissue RNA - gallbladder [nTPM]":"40.6","Tissue RNA - heart muscle [nTPM]":"34.4","Tissue RNA - hippocampal formation [nTPM]":"55.0","Tissue RNA - hypothalamus [nTPM]":"77.3","Tissue RNA - kidney [nTPM]":"67.9","Tissue RNA - liver [nTPM]":"73.8","Tissue RNA - lung [nTPM]":"64.1","Tissue RNA - lymph node [nTPM]":"38.0","Tissue RNA - medulla oblongata [nTPM]":"101.8","Tissue RNA - midbrain [nTPM]":"83.9","Tissue RNA - ovary [nTPM]":"35.6","Tissue RNA - pancreas [nTPM]":"36.1","Tissue RNA - parathyroid gland [nTPM]":"52.3","Tissue RNA - pituitary gland [nTPM]":"18.3","Tissue RNA - placenta [nTPM]":"64.1","Tissue RNA - pons [nTPM]":"100.8","Tissue RNA - prostate [nTPM]":"46.6","Tissue RNA - rectum [nTPM]":"37.1","Tissue RNA - retina [nTPM]":"40.4","Tissue RNA - salivary gland [nTPM]":"75.5","Tissue RNA - seminal vesicle [nTPM]":"39.3","Tissue RNA - skeletal muscle [nTPM]":"36.5","Tissue RNA - skin 1 [nTPM]":"32.5","Tissue RNA - small intestine [nTPM]":"30.5","Tissue RNA - smooth muscle [nTPM]":"36.9","Tissue RNA - spinal cord [nTPM]":"85.6","Tissue RNA - spleen [nTPM]":"53.0","Tissue RNA - stomach 1 [nTPM]":"34.3","Tissue RNA - testis [nTPM]":"25.2","Tissue RNA - thalamus [nTPM]":"75.9","Tissue RNA - thymus [nTPM]":"32.0","Tissue RNA - thyroid gland [nTPM]":"64.0","Tissue RNA - tongue [nTPM]":"42.6","Tissue RNA - tonsil [nTPM]":"33.2","Tissue RNA - urinary bladder [nTPM]":"42.3","Tissue RNA - vagina [nTPM]":"28.9","Tissue RNA - white matter [nTPM]":"131.0","Cell RNA - A-431 [nTPM]":"60.6","Cell RNA - A549 [nTPM]":"39.4","Cell RNA - AF22 [nTPM]":"24.4","Cell RNA - AN3-CA [nTPM]":"29.0","Cell RNA - ASC diff [nTPM]":"92.2","Cell RNA - ASC TERT1 [nTPM]":"55.2","Cell RNA - BEWO [nTPM]":"40.3","Cell RNA - BJ [nTPM]":"32.2","Cell RNA - BJ hTERT+ [nTPM]":"86.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.4","Cell RNA - CACO-2 [nTPM]":"33.4","Cell RNA - CAPAN-2 [nTPM]":"84.4","Cell RNA - Daudi [nTPM]":"26.6","Cell RNA - EFO-21 [nTPM]":"48.7","Cell RNA - fHDF\/TERT166 [nTPM]":"42.0","Cell RNA - GAMG [nTPM]":"58.7","Cell RNA - HaCaT [nTPM]":"58.0","Cell RNA - HAP1 [nTPM]":"37.5","Cell RNA - HBEC3-KT [nTPM]":"41.5","Cell RNA - HBF TERT88 [nTPM]":"42.9","Cell RNA - HDLM-2 [nTPM]":"34.1","Cell RNA - HEK 293 [nTPM]":"24.6","Cell RNA - HEL [nTPM]":"35.8","Cell RNA - HeLa [nTPM]":"17.3","Cell RNA - Hep G2 [nTPM]":"31.2","Cell RNA - HHSteC [nTPM]":"61.5","Cell RNA - HL-60 [nTPM]":"35.0","Cell RNA - HMC-1 [nTPM]":"41.8","Cell RNA - HSkMC [nTPM]":"59.9","Cell RNA - hTCEpi [nTPM]":"73.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.5","Cell RNA - hTERT-HME1 [nTPM]":"71.8","Cell RNA - hTERT-RPE1 [nTPM]":"37.3","Cell RNA - HUVEC TERT2 [nTPM]":"37.0","Cell RNA - JURKAT [nTPM]":"24.9","Cell RNA - K-562 [nTPM]":"10.1","Cell RNA - Karpas-707 [nTPM]":"49.7","Cell RNA - LHCN-M2 [nTPM]":"28.0","Cell RNA - MCF7 [nTPM]":"34.5","Cell RNA - MOLT-4 [nTPM]":"26.2","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"16.8","Cell RNA - OE19 [nTPM]":"58.6","Cell RNA - PC-3 [nTPM]":"29.1","Cell RNA - REH [nTPM]":"19.0","Cell RNA - RH-30 [nTPM]":"26.7","Cell RNA - RPMI-8226 [nTPM]":"108.5","Cell RNA - RPTEC TERT1 [nTPM]":"54.2","Cell RNA - RT4 [nTPM]":"29.6","Cell RNA - SCLC-21H [nTPM]":"12.6","Cell RNA - SH-SY5Y [nTPM]":"37.6","Cell RNA - SiHa [nTPM]":"28.5","Cell RNA - SK-BR-3 [nTPM]":"39.9","Cell RNA - SK-MEL-30 [nTPM]":"110.3","Cell RNA - SuSa [nTPM]":"19.2","Cell RNA - T-47d [nTPM]":"79.2","Cell RNA - THP-1 [nTPM]":"34.0","Cell RNA - TIME [nTPM]":"37.8","Cell RNA - U-138 MG [nTPM]":"40.8","Cell RNA - U-2 OS [nTPM]":"16.5","Cell RNA - U-2197 [nTPM]":"45.6","Cell RNA - U-251 MG [nTPM]":"23.4","Cell RNA - U-266\/70 [nTPM]":"89.9","Cell RNA - U-266\/84 [nTPM]":"61.9","Cell RNA - U-698 [nTPM]":"51.5","Cell RNA - U-87 MG [nTPM]":"35.9","Cell RNA - U-937 [nTPM]":"30.1","Cell RNA - WM-115 [nTPM]":"23.6","Blood RNA - basophil [nTPM]":"98.2","Blood RNA - classical monocyte [nTPM]":"130.1","Blood RNA - eosinophil [nTPM]":"106.5","Blood RNA - gdT-cell [nTPM]":"37.4","Blood RNA - intermediate monocyte [nTPM]":"153.8","Blood RNA - MAIT T-cell [nTPM]":"48.8","Blood RNA - memory B-cell [nTPM]":"51.9","Blood RNA - memory CD4 T-cell [nTPM]":"41.5","Blood RNA - memory CD8 T-cell [nTPM]":"44.8","Blood RNA - myeloid DC [nTPM]":"93.1","Blood RNA - naive B-cell [nTPM]":"48.4","Blood RNA - naive CD4 T-cell [nTPM]":"38.0","Blood RNA - naive CD8 T-cell [nTPM]":"42.4","Blood RNA - neutrophil [nTPM]":"462.3","Blood RNA - NK-cell [nTPM]":"46.3","Blood RNA - non-classical monocyte [nTPM]":"207.8","Blood RNA - plasmacytoid DC [nTPM]":"68.3","Blood RNA - T-reg [nTPM]":"48.7","Blood RNA - total PBMC [nTPM]":"104.5","Brain RNA - amygdala [nTPM]":"58.1","Brain RNA - basal ganglia [nTPM]":"95.2","Brain RNA - cerebellum [nTPM]":"88.1","Brain RNA - cerebral cortex [nTPM]":"91.5","Brain RNA - hippocampal formation [nTPM]":"55.0","Brain RNA - hypothalamus [nTPM]":"77.3","Brain RNA - medulla oblongata [nTPM]":"101.8","Brain RNA - midbrain [nTPM]":"83.9","Brain RNA - pons [nTPM]":"100.8","Brain RNA - spinal cord [nTPM]":"85.6","Brain RNA - thalamus [nTPM]":"75.9","Brain RNA - white matter [nTPM]":"131.0","Single Cell Type RNA - Adipocytes [nTPM]":"100.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"109.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"72.3","Single Cell Type RNA - Astrocytes [nTPM]":"78.7","Single Cell Type RNA - B-cells [nTPM]":"55.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"73.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"68.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"84.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"74.0","Single Cell Type RNA - Bipolar cells [nTPM]":"44.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"54.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"51.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"68.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.2","Single Cell Type RNA - dendritic cells [nTPM]":"61.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"63.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.5","Single Cell Type RNA - Endothelial cells [nTPM]":"69.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"32.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"122.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"70.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"83.5","Single Cell Type RNA - Fibroblasts [nTPM]":"84.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.7","Single Cell Type RNA - granulocytes [nTPM]":"60.8","Single Cell Type RNA - Granulosa cells [nTPM]":"14.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"80.3","Single Cell Type RNA - Hepatocytes [nTPM]":"53.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"201.2","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"98.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.7","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"183.9","Single Cell Type RNA - Langerhans cells [nTPM]":"173.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"76.1","Single Cell Type RNA - Macrophages [nTPM]":"177.6","Single Cell Type RNA - Melanocytes [nTPM]":"103.2","Single Cell Type RNA - Microglial cells [nTPM]":"92.8","Single Cell Type RNA - monocytes [nTPM]":"93.5","Single Cell Type RNA - Muller glia cells [nTPM]":"98.5","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"115.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"591.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.7","Single Cell Type RNA - Paneth cells [nTPM]":"33.6","Single Cell Type RNA - Peritubular cells [nTPM]":"88.0","Single Cell Type RNA - Plasma cells [nTPM]":"62.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"71.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"71.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.2","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"76.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.5","Single Cell Type RNA - Spermatocytes [nTPM]":"23.6","Single Cell Type RNA - Spermatogonia [nTPM]":"32.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"72.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.5","Single Cell Type RNA - T-cells [nTPM]":"49.8","Single Cell Type RNA - Theca cells [nTPM]":"38.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.7","Single Cell Type RNA - Urothelial cells [nTPM]":"55.8"},{"Gene":"RNF170","Gene synonym":["ADSA","DKFZP564A022","SNAX1"],"Ensembl":"ENSG00000120925","Gene description":"Ring finger protein 170","Uniprot":["Q96K19"],"Chromosome":"8","Position":"42849637-42897290","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"89.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050931","HPA054621"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050931":"AB_2681279","HPA054621":"AB_2682545"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"11.7","Tissue RNA - amygdala [nTPM]":"14.5","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"15.6","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"12.7","Tissue RNA - cerebellum [nTPM]":"16.3","Tissue RNA - cerebral cortex [nTPM]":"16.8","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"11.5","Tissue RNA - colon [nTPM]":"11.1","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"9.5","Tissue RNA - epididymis [nTPM]":"14.9","Tissue RNA - esophagus [nTPM]":"14.2","Tissue RNA - fallopian tube [nTPM]":"9.3","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"15.8","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"19.7","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"15.9","Tissue RNA - midbrain [nTPM]":"15.5","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"13.5","Tissue RNA - pituitary gland [nTPM]":"9.5","Tissue RNA - placenta [nTPM]":"19.2","Tissue RNA - pons [nTPM]":"16.2","Tissue RNA - prostate [nTPM]":"11.0","Tissue RNA - rectum [nTPM]":"11.3","Tissue RNA - retina [nTPM]":"35.6","Tissue RNA - salivary gland [nTPM]":"11.0","Tissue RNA - seminal vesicle [nTPM]":"10.6","Tissue RNA - skeletal muscle [nTPM]":"11.9","Tissue RNA - skin 1 [nTPM]":"15.1","Tissue RNA - small intestine [nTPM]":"11.4","Tissue RNA - smooth muscle [nTPM]":"7.6","Tissue RNA - spinal cord [nTPM]":"15.0","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"10.7","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"6.1","Tissue RNA - thyroid gland [nTPM]":"28.8","Tissue RNA - tongue [nTPM]":"9.2","Tissue RNA - tonsil [nTPM]":"9.9","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"18.3","Cell RNA - A-431 [nTPM]":"11.4","Cell RNA - A549 [nTPM]":"18.1","Cell RNA - AF22 [nTPM]":"18.2","Cell RNA - AN3-CA [nTPM]":"9.2","Cell RNA - ASC diff [nTPM]":"29.4","Cell RNA - ASC TERT1 [nTPM]":"29.7","Cell RNA - BEWO [nTPM]":"10.8","Cell RNA - BJ [nTPM]":"13.3","Cell RNA - BJ hTERT+ [nTPM]":"18.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.2","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"36.0","Cell RNA - Daudi [nTPM]":"13.6","Cell RNA - EFO-21 [nTPM]":"15.7","Cell RNA - fHDF\/TERT166 [nTPM]":"12.8","Cell RNA - GAMG [nTPM]":"22.1","Cell RNA - HaCaT [nTPM]":"9.6","Cell RNA - HAP1 [nTPM]":"9.6","Cell RNA - HBEC3-KT [nTPM]":"13.2","Cell RNA - HBF TERT88 [nTPM]":"10.8","Cell RNA - HDLM-2 [nTPM]":"9.4","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"15.9","Cell RNA - HeLa [nTPM]":"8.5","Cell RNA - Hep G2 [nTPM]":"9.3","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"10.9","Cell RNA - HSkMC [nTPM]":"26.0","Cell RNA - hTCEpi [nTPM]":"20.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.3","Cell RNA - hTERT-HME1 [nTPM]":"18.8","Cell RNA - hTERT-RPE1 [nTPM]":"16.0","Cell RNA - HUVEC TERT2 [nTPM]":"13.3","Cell RNA - JURKAT [nTPM]":"15.0","Cell RNA - K-562 [nTPM]":"14.6","Cell RNA - Karpas-707 [nTPM]":"15.8","Cell RNA - LHCN-M2 [nTPM]":"19.9","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"17.0","Cell RNA - NB-4 [nTPM]":"9.5","Cell RNA - NTERA-2 [nTPM]":"8.6","Cell RNA - OE19 [nTPM]":"24.1","Cell RNA - PC-3 [nTPM]":"6.5","Cell RNA - REH [nTPM]":"8.7","Cell RNA - RH-30 [nTPM]":"24.2","Cell RNA - RPMI-8226 [nTPM]":"7.7","Cell RNA - RPTEC TERT1 [nTPM]":"19.6","Cell RNA - RT4 [nTPM]":"10.8","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"14.3","Cell RNA - SiHa [nTPM]":"12.8","Cell RNA - SK-BR-3 [nTPM]":"8.9","Cell RNA - SK-MEL-30 [nTPM]":"23.0","Cell RNA - SuSa [nTPM]":"17.7","Cell RNA - T-47d [nTPM]":"23.1","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"19.5","Cell RNA - U-138 MG [nTPM]":"13.2","Cell RNA - U-2 OS [nTPM]":"5.8","Cell RNA - U-2197 [nTPM]":"17.8","Cell RNA - U-251 MG [nTPM]":"4.3","Cell RNA - U-266\/70 [nTPM]":"25.2","Cell RNA - U-266\/84 [nTPM]":"26.4","Cell RNA - U-698 [nTPM]":"15.7","Cell RNA - U-87 MG [nTPM]":"18.2","Cell RNA - U-937 [nTPM]":"6.7","Cell RNA - WM-115 [nTPM]":"13.6","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"5.7","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"2.9","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"4.2","Blood RNA - memory B-cell [nTPM]":"6.6","Blood RNA - memory CD4 T-cell [nTPM]":"4.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"8.8","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"5.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"4.9","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"8.9","Blood RNA - T-reg [nTPM]":"6.7","Blood RNA - total PBMC [nTPM]":"4.5","Brain RNA - amygdala [nTPM]":"14.5","Brain RNA - basal ganglia [nTPM]":"15.6","Brain RNA - cerebellum [nTPM]":"16.3","Brain RNA - cerebral cortex [nTPM]":"16.8","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"15.8","Brain RNA - medulla oblongata [nTPM]":"15.9","Brain RNA - midbrain [nTPM]":"15.5","Brain RNA - pons [nTPM]":"16.2","Brain RNA - spinal cord [nTPM]":"15.0","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"18.3","Single Cell Type RNA - Adipocytes [nTPM]":"13.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.5","Single Cell Type RNA - Astrocytes [nTPM]":"41.1","Single Cell Type RNA - B-cells [nTPM]":"16.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"44.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"29.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"89.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.6","Single Cell Type RNA - dendritic cells [nTPM]":"9.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"21.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.5","Single Cell Type RNA - Endothelial cells [nTPM]":"15.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.4","Single Cell Type RNA - Fibroblasts [nTPM]":"20.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"21.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.9","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"9.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"15.4","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"21.9","Single Cell Type RNA - Muller glia cells [nTPM]":"31.8","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"75.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.2","Single Cell Type RNA - Paneth cells [nTPM]":"18.4","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"10.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"72.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.1","Single Cell Type RNA - Spermatocytes [nTPM]":"14.9","Single Cell Type RNA - Spermatogonia [nTPM]":"19.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"25.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.6","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"RNF216","Gene synonym":["TRIAD3","UBCE7IP1","ZIN"],"Ensembl":"ENSG00000011275","Gene description":"Ring finger protein 216","Uniprot":["Q9NWF9"],"Chromosome":"7","Position":"5620047-5781696","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"145.5","Late spermatids":"257.6","Spermatocytes":"159.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018955","HPA021123"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA018955":"AB_1858500","HPA021123":"AB_1858501"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.24e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.3","Tissue RNA - adrenal gland [nTPM]":"12.3","Tissue RNA - amygdala [nTPM]":"14.3","Tissue RNA - appendix [nTPM]":"12.8","Tissue RNA - basal ganglia [nTPM]":"15.9","Tissue RNA - bone marrow [nTPM]":"15.6","Tissue RNA - breast [nTPM]":"13.1","Tissue RNA - cerebellum [nTPM]":"12.6","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"13.2","Tissue RNA - choroid plexus [nTPM]":"10.0","Tissue RNA - colon [nTPM]":"25.5","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"21.9","Tissue RNA - epididymis [nTPM]":"8.2","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"15.8","Tissue RNA - gallbladder [nTPM]":"8.7","Tissue RNA - heart muscle [nTPM]":"21.7","Tissue RNA - hippocampal formation [nTPM]":"13.8","Tissue RNA - hypothalamus [nTPM]":"17.5","Tissue RNA - kidney [nTPM]":"10.0","Tissue RNA - liver [nTPM]":"10.1","Tissue RNA - lung [nTPM]":"12.8","Tissue RNA - lymph node [nTPM]":"17.0","Tissue RNA - medulla oblongata [nTPM]":"14.9","Tissue RNA - midbrain [nTPM]":"15.4","Tissue RNA - ovary [nTPM]":"16.5","Tissue RNA - pancreas [nTPM]":"14.9","Tissue RNA - parathyroid gland [nTPM]":"13.9","Tissue RNA - pituitary gland [nTPM]":"15.4","Tissue RNA - placenta [nTPM]":"7.7","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"13.7","Tissue RNA - skeletal muscle [nTPM]":"19.6","Tissue RNA - skin 1 [nTPM]":"13.3","Tissue RNA - small intestine [nTPM]":"17.9","Tissue RNA - smooth muscle [nTPM]":"15.0","Tissue RNA - spinal cord [nTPM]":"12.8","Tissue RNA - spleen [nTPM]":"19.2","Tissue RNA - stomach 1 [nTPM]":"14.6","Tissue RNA - testis [nTPM]":"30.1","Tissue RNA - thalamus [nTPM]":"16.2","Tissue RNA - thymus [nTPM]":"12.8","Tissue RNA - thyroid gland [nTPM]":"12.7","Tissue RNA - tongue [nTPM]":"11.9","Tissue RNA - tonsil [nTPM]":"11.5","Tissue RNA - urinary bladder [nTPM]":"16.4","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"22.0","Cell RNA - A549 [nTPM]":"23.6","Cell RNA - AF22 [nTPM]":"17.0","Cell RNA - AN3-CA [nTPM]":"32.8","Cell RNA - ASC diff [nTPM]":"21.6","Cell RNA - ASC TERT1 [nTPM]":"14.6","Cell RNA - BEWO [nTPM]":"11.5","Cell RNA - BJ [nTPM]":"20.7","Cell RNA - BJ hTERT+ [nTPM]":"19.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.8","Cell RNA - CACO-2 [nTPM]":"16.7","Cell RNA - CAPAN-2 [nTPM]":"12.3","Cell RNA - Daudi [nTPM]":"17.3","Cell RNA - EFO-21 [nTPM]":"11.4","Cell RNA - fHDF\/TERT166 [nTPM]":"22.0","Cell RNA - GAMG [nTPM]":"38.7","Cell RNA - HaCaT [nTPM]":"17.1","Cell RNA - HAP1 [nTPM]":"13.6","Cell RNA - HBEC3-KT [nTPM]":"15.3","Cell RNA - HBF TERT88 [nTPM]":"10.3","Cell RNA - HDLM-2 [nTPM]":"11.4","Cell RNA - HEK 293 [nTPM]":"19.3","Cell RNA - HEL [nTPM]":"12.5","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"18.0","Cell RNA - HHSteC [nTPM]":"27.7","Cell RNA - HL-60 [nTPM]":"19.5","Cell RNA - HMC-1 [nTPM]":"25.3","Cell RNA - HSkMC [nTPM]":"21.4","Cell RNA - hTCEpi [nTPM]":"20.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.2","Cell RNA - hTERT-HME1 [nTPM]":"14.6","Cell RNA - hTERT-RPE1 [nTPM]":"18.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.0","Cell RNA - JURKAT [nTPM]":"19.2","Cell RNA - K-562 [nTPM]":"28.4","Cell RNA - Karpas-707 [nTPM]":"12.9","Cell RNA - LHCN-M2 [nTPM]":"18.9","Cell RNA - MCF7 [nTPM]":"35.2","Cell RNA - MOLT-4 [nTPM]":"8.8","Cell RNA - NB-4 [nTPM]":"44.7","Cell RNA - NTERA-2 [nTPM]":"25.7","Cell RNA - OE19 [nTPM]":"13.1","Cell RNA - PC-3 [nTPM]":"20.0","Cell RNA - REH [nTPM]":"26.1","Cell RNA - RH-30 [nTPM]":"23.4","Cell RNA - RPMI-8226 [nTPM]":"12.2","Cell RNA - RPTEC TERT1 [nTPM]":"13.9","Cell RNA - RT4 [nTPM]":"13.9","Cell RNA - SCLC-21H [nTPM]":"14.1","Cell RNA - SH-SY5Y [nTPM]":"25.3","Cell RNA - SiHa [nTPM]":"11.8","Cell RNA - SK-BR-3 [nTPM]":"33.9","Cell RNA - SK-MEL-30 [nTPM]":"13.2","Cell RNA - SuSa [nTPM]":"15.3","Cell RNA - T-47d [nTPM]":"14.2","Cell RNA - THP-1 [nTPM]":"28.2","Cell RNA - TIME [nTPM]":"20.5","Cell RNA - U-138 MG [nTPM]":"24.9","Cell RNA - U-2 OS [nTPM]":"39.9","Cell RNA - U-2197 [nTPM]":"25.2","Cell RNA - U-251 MG [nTPM]":"22.8","Cell RNA - U-266\/70 [nTPM]":"11.4","Cell RNA - U-266\/84 [nTPM]":"9.0","Cell RNA - U-698 [nTPM]":"16.0","Cell RNA - U-87 MG [nTPM]":"19.6","Cell RNA - U-937 [nTPM]":"21.7","Cell RNA - WM-115 [nTPM]":"37.4","Blood RNA - basophil [nTPM]":"3.5","Blood RNA - classical monocyte [nTPM]":"7.7","Blood RNA - eosinophil [nTPM]":"24.2","Blood RNA - gdT-cell [nTPM]":"10.1","Blood RNA - intermediate monocyte [nTPM]":"8.3","Blood RNA - MAIT T-cell [nTPM]":"9.4","Blood RNA - memory B-cell [nTPM]":"8.3","Blood RNA - memory CD4 T-cell [nTPM]":"9.3","Blood RNA - memory CD8 T-cell [nTPM]":"8.7","Blood RNA - myeloid DC [nTPM]":"6.3","Blood RNA - naive B-cell [nTPM]":"8.8","Blood RNA - naive CD4 T-cell [nTPM]":"10.9","Blood RNA - naive CD8 T-cell [nTPM]":"11.3","Blood RNA - neutrophil [nTPM]":"13.2","Blood RNA - NK-cell [nTPM]":"12.7","Blood RNA - non-classical monocyte [nTPM]":"8.7","Blood RNA - plasmacytoid DC [nTPM]":"7.1","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"6.9","Brain RNA - amygdala [nTPM]":"14.3","Brain RNA - basal ganglia [nTPM]":"15.9","Brain RNA - cerebellum [nTPM]":"12.6","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"13.8","Brain RNA - hypothalamus [nTPM]":"17.5","Brain RNA - medulla oblongata [nTPM]":"14.9","Brain RNA - midbrain [nTPM]":"15.4","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"12.8","Brain RNA - thalamus [nTPM]":"16.2","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"33.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.9","Single Cell Type RNA - Astrocytes [nTPM]":"34.9","Single Cell Type RNA - B-cells [nTPM]":"33.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"36.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"13.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - dendritic cells [nTPM]":"47.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"17.6","Single Cell Type RNA - Early spermatids [nTPM]":"145.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.7","Single Cell Type RNA - Endothelial cells [nTPM]":"29.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.9","Single Cell Type RNA - Fibroblasts [nTPM]":"26.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.9","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"34.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"15.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.9","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"61.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"23.0","Single Cell Type RNA - Langerhans cells [nTPM]":"29.3","Single Cell Type RNA - Late spermatids [nTPM]":"257.6","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"23.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"37.0","Single Cell Type RNA - Muller glia cells [nTPM]":"30.2","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"46.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"64.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.0","Single Cell Type RNA - Peritubular cells [nTPM]":"30.1","Single Cell Type RNA - Plasma cells [nTPM]":"20.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.0","Single Cell Type RNA - Spermatocytes [nTPM]":"159.8","Single Cell Type RNA - Spermatogonia [nTPM]":"124.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - T-cells [nTPM]":"40.2","Single Cell Type RNA - Theca cells [nTPM]":"22.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.8","Single Cell Type RNA - Urothelial cells [nTPM]":"15.2"},{"Gene":"ROBO3","Gene synonym":["FLJ21044","HGPPS","HGPS","RBIG1"],"Ensembl":"ENSG00000154134","Gene description":"Roundabout guidance receptor 3","Uniprot":["Q96MS0"],"Chromosome":"11","Position":"124865432-124881471","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Chemotaxis","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"6.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"32.3","Muller glia cells":"45.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"AF22":"18.4"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"2.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071053"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA071053":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.8","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"3.2","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"2.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"1.2","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"18.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.5","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"3.2","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"13.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.3","Single Cell Type RNA - Astrocytes [nTPM]":"32.3","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"5.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"8.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"11.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"19.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"19.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"45.3","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"10.1","Single Cell Type RNA - Spermatogonia [nTPM]":"10.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"3.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.7","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"ROGDI","Gene synonym":["FLJ22386"],"Ensembl":"ENSG00000067836","Gene description":"Rogdi atypical leucine zipper","Uniprot":["Q9GZN7"],"Chromosome":"16","Position":"4796968-4802880","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"105.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"179.2","Rod photoreceptor cells":"149.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"74.6","intermediate monocyte":"62.7","myeloid DC":"61.5","non-classical monocyte":"61.8","plasmacytoid DC":"34.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"61.5","monocytes":"74.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041000"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041000":"AB_10794077"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.71e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.5","Tissue RNA - adrenal gland [nTPM]":"24.1","Tissue RNA - amygdala [nTPM]":"82.9","Tissue RNA - appendix [nTPM]":"11.6","Tissue RNA - basal ganglia [nTPM]":"84.5","Tissue RNA - bone marrow [nTPM]":"78.0","Tissue RNA - breast [nTPM]":"7.3","Tissue RNA - cerebellum [nTPM]":"81.3","Tissue RNA - cerebral cortex [nTPM]":"105.6","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"64.3","Tissue RNA - colon [nTPM]":"17.6","Tissue RNA - duodenum [nTPM]":"24.8","Tissue RNA - endometrium 1 [nTPM]":"7.5","Tissue RNA - epididymis [nTPM]":"6.6","Tissue RNA - esophagus [nTPM]":"18.1","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"14.4","Tissue RNA - heart muscle [nTPM]":"44.2","Tissue RNA - hippocampal formation [nTPM]":"91.4","Tissue RNA - hypothalamus [nTPM]":"83.9","Tissue RNA - kidney [nTPM]":"19.3","Tissue RNA - liver [nTPM]":"19.7","Tissue RNA - lung [nTPM]":"15.5","Tissue RNA - lymph node [nTPM]":"8.6","Tissue RNA - medulla oblongata [nTPM]":"84.0","Tissue RNA - midbrain [nTPM]":"84.9","Tissue RNA - ovary [nTPM]":"5.9","Tissue RNA - pancreas [nTPM]":"22.9","Tissue RNA - parathyroid gland [nTPM]":"26.4","Tissue RNA - pituitary gland [nTPM]":"18.2","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"80.9","Tissue RNA - prostate [nTPM]":"19.0","Tissue RNA - rectum [nTPM]":"7.6","Tissue RNA - retina [nTPM]":"61.9","Tissue RNA - salivary gland [nTPM]":"25.3","Tissue RNA - seminal vesicle [nTPM]":"16.6","Tissue RNA - skeletal muscle [nTPM]":"63.1","Tissue RNA - skin 1 [nTPM]":"6.5","Tissue RNA - small intestine [nTPM]":"21.4","Tissue RNA - smooth muscle [nTPM]":"11.3","Tissue RNA - spinal cord [nTPM]":"79.4","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"21.1","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"96.8","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"32.9","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"11.2","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"97.6","Cell RNA - A-431 [nTPM]":"13.5","Cell RNA - A549 [nTPM]":"18.8","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"42.4","Cell RNA - ASC diff [nTPM]":"12.2","Cell RNA - ASC TERT1 [nTPM]":"6.2","Cell RNA - BEWO [nTPM]":"36.4","Cell RNA - BJ [nTPM]":"9.4","Cell RNA - BJ hTERT+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.6","Cell RNA - CACO-2 [nTPM]":"12.5","Cell RNA - CAPAN-2 [nTPM]":"15.3","Cell RNA - Daudi [nTPM]":"5.9","Cell RNA - EFO-21 [nTPM]":"15.1","Cell RNA - fHDF\/TERT166 [nTPM]":"19.9","Cell RNA - GAMG [nTPM]":"5.3","Cell RNA - HaCaT [nTPM]":"26.7","Cell RNA - HAP1 [nTPM]":"9.9","Cell RNA - HBEC3-KT [nTPM]":"28.7","Cell RNA - HBF TERT88 [nTPM]":"3.2","Cell RNA - HDLM-2 [nTPM]":"4.8","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"8.0","Cell RNA - HeLa [nTPM]":"28.9","Cell RNA - Hep G2 [nTPM]":"28.1","Cell RNA - HHSteC [nTPM]":"19.8","Cell RNA - HL-60 [nTPM]":"10.4","Cell RNA - HMC-1 [nTPM]":"6.5","Cell RNA - HSkMC [nTPM]":"8.3","Cell RNA - hTCEpi [nTPM]":"11.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.4","Cell RNA - hTERT-HME1 [nTPM]":"8.3","Cell RNA - hTERT-RPE1 [nTPM]":"21.6","Cell RNA - HUVEC TERT2 [nTPM]":"14.5","Cell RNA - JURKAT [nTPM]":"11.5","Cell RNA - K-562 [nTPM]":"5.7","Cell RNA - Karpas-707 [nTPM]":"3.5","Cell RNA - LHCN-M2 [nTPM]":"14.1","Cell RNA - MCF7 [nTPM]":"74.9","Cell RNA - MOLT-4 [nTPM]":"9.4","Cell RNA - NB-4 [nTPM]":"51.0","Cell RNA - NTERA-2 [nTPM]":"15.3","Cell RNA - OE19 [nTPM]":"15.4","Cell RNA - PC-3 [nTPM]":"14.2","Cell RNA - REH [nTPM]":"30.1","Cell RNA - RH-30 [nTPM]":"26.1","Cell RNA - RPMI-8226 [nTPM]":"30.1","Cell RNA - RPTEC TERT1 [nTPM]":"19.8","Cell RNA - RT4 [nTPM]":"18.1","Cell RNA - SCLC-21H [nTPM]":"55.3","Cell RNA - SH-SY5Y [nTPM]":"24.5","Cell RNA - SiHa [nTPM]":"38.6","Cell RNA - SK-BR-3 [nTPM]":"42.4","Cell RNA - SK-MEL-30 [nTPM]":"9.9","Cell RNA - SuSa [nTPM]":"11.9","Cell RNA - T-47d [nTPM]":"50.9","Cell RNA - THP-1 [nTPM]":"40.8","Cell RNA - TIME [nTPM]":"22.3","Cell RNA - U-138 MG [nTPM]":"7.3","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"52.5","Cell RNA - U-251 MG [nTPM]":"6.5","Cell RNA - U-266\/70 [nTPM]":"14.2","Cell RNA - U-266\/84 [nTPM]":"17.0","Cell RNA - U-698 [nTPM]":"5.2","Cell RNA - U-87 MG [nTPM]":"8.6","Cell RNA - U-937 [nTPM]":"40.0","Cell RNA - WM-115 [nTPM]":"6.5","Blood RNA - basophil [nTPM]":"10.5","Blood RNA - classical monocyte [nTPM]":"74.6","Blood RNA - eosinophil [nTPM]":"8.1","Blood RNA - gdT-cell [nTPM]":"2.1","Blood RNA - intermediate monocyte [nTPM]":"62.7","Blood RNA - MAIT T-cell [nTPM]":"6.6","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"5.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"61.5","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.7","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"6.7","Blood RNA - NK-cell [nTPM]":"6.7","Blood RNA - non-classical monocyte [nTPM]":"61.8","Blood RNA - plasmacytoid DC [nTPM]":"34.5","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"38.0","Brain RNA - amygdala [nTPM]":"82.9","Brain RNA - basal ganglia [nTPM]":"84.5","Brain RNA - cerebellum [nTPM]":"81.3","Brain RNA - cerebral cortex [nTPM]":"105.6","Brain RNA - hippocampal formation [nTPM]":"91.4","Brain RNA - hypothalamus [nTPM]":"83.9","Brain RNA - medulla oblongata [nTPM]":"84.0","Brain RNA - midbrain [nTPM]":"84.9","Brain RNA - pons [nTPM]":"80.9","Brain RNA - spinal cord [nTPM]":"79.4","Brain RNA - thalamus [nTPM]":"96.8","Brain RNA - white matter [nTPM]":"97.6","Single Cell Type RNA - Adipocytes [nTPM]":"7.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"6.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"84.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"32.5","Single Cell Type RNA - Bipolar cells [nTPM]":"179.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"58.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"36.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"110.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.9","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"22.2","Single Cell Type RNA - Early spermatids [nTPM]":"30.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.5","Single Cell Type RNA - Endothelial cells [nTPM]":"12.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"52.0","Single Cell Type RNA - Erythroid cells [nTPM]":"38.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"73.4","Single Cell Type RNA - Fibroblasts [nTPM]":"15.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.2","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"9.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"19.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"64.8","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.7","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.7","Single Cell Type RNA - Langerhans cells [nTPM]":"29.0","Single Cell Type RNA - Late spermatids [nTPM]":"57.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"31.0","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"77.0","Single Cell Type RNA - Muller glia cells [nTPM]":"102.5","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"90.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.5","Single Cell Type RNA - Paneth cells [nTPM]":"23.7","Single Cell Type RNA - Peritubular cells [nTPM]":"19.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"65.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"80.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"149.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.6","Single Cell Type RNA - T-cells [nTPM]":"9.5","Single Cell Type RNA - Theca cells [nTPM]":"64.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.1","Single Cell Type RNA - Urothelial cells [nTPM]":"22.3"},{"Gene":"ROM1","Gene synonym":["ROM","TSPAN23"],"Ensembl":"ENSG00000149489","Gene description":"Retinal outer segment membrane protein 1","Uniprot":["Q03395"],"Chromosome":"11","Position":"62611722-62615116","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"retina":"1186.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"3239.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"14.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"2.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"NK-cells":"2.7","T-cells":"1.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HSkMC":"25.2","U-266\/84":"31.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028910","HPA073279"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028910":"AB_2672824","HPA073279":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.85e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.8","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"57.9","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"60.5","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"9.3","Tissue RNA - cerebellum [nTPM]":"56.8","Tissue RNA - cerebral cortex [nTPM]":"67.4","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"48.1","Tissue RNA - colon [nTPM]":"9.8","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"8.1","Tissue RNA - hippocampal formation [nTPM]":"54.5","Tissue RNA - hypothalamus [nTPM]":"59.0","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"7.1","Tissue RNA - lung [nTPM]":"6.0","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"67.4","Tissue RNA - midbrain [nTPM]":"61.0","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"3.6","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"7.0","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"62.1","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"1186.9","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"60.0","Tissue RNA - spleen [nTPM]":"7.5","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"63.1","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"62.1","Cell RNA - A-431 [nTPM]":"3.2","Cell RNA - A549 [nTPM]":"1.9","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"6.6","Cell RNA - ASC diff [nTPM]":"4.5","Cell RNA - ASC TERT1 [nTPM]":"22.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"2.1","Cell RNA - BJ hTERT+ [nTPM]":"3.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.8","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"3.0","Cell RNA - EFO-21 [nTPM]":"15.9","Cell RNA - fHDF\/TERT166 [nTPM]":"12.2","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"4.1","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"4.2","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"5.3","Cell RNA - HEK 293 [nTPM]":"3.0","Cell RNA - HEL [nTPM]":"3.1","Cell RNA - HeLa [nTPM]":"8.6","Cell RNA - Hep G2 [nTPM]":"4.0","Cell RNA - HHSteC [nTPM]":"13.0","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"25.2","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.5","Cell RNA - hTERT-HME1 [nTPM]":"9.1","Cell RNA - hTERT-RPE1 [nTPM]":"15.1","Cell RNA - HUVEC TERT2 [nTPM]":"7.0","Cell RNA - JURKAT [nTPM]":"1.2","Cell RNA - K-562 [nTPM]":"4.0","Cell RNA - Karpas-707 [nTPM]":"6.5","Cell RNA - LHCN-M2 [nTPM]":"9.1","Cell RNA - MCF7 [nTPM]":"8.3","Cell RNA - MOLT-4 [nTPM]":"1.7","Cell RNA - NB-4 [nTPM]":"2.3","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"1.7","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"19.1","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"1.8","Cell RNA - SCLC-21H [nTPM]":"3.3","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"5.0","Cell RNA - SK-BR-3 [nTPM]":"5.8","Cell RNA - SK-MEL-30 [nTPM]":"2.5","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"8.1","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"8.3","Cell RNA - U-138 MG [nTPM]":"7.2","Cell RNA - U-2 OS [nTPM]":"2.7","Cell RNA - U-2197 [nTPM]":"8.3","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"2.9","Cell RNA - U-266\/84 [nTPM]":"31.9","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"14.2","Cell RNA - U-937 [nTPM]":"3.1","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"57.9","Brain RNA - basal ganglia [nTPM]":"60.5","Brain RNA - cerebellum [nTPM]":"56.8","Brain RNA - cerebral cortex [nTPM]":"67.4","Brain RNA - hippocampal formation [nTPM]":"54.5","Brain RNA - hypothalamus [nTPM]":"59.0","Brain RNA - medulla oblongata [nTPM]":"67.4","Brain RNA - midbrain [nTPM]":"61.0","Brain RNA - pons [nTPM]":"62.1","Brain RNA - spinal cord [nTPM]":"60.0","Brain RNA - thalamus [nTPM]":"63.1","Brain RNA - white matter [nTPM]":"62.1","Single Cell Type RNA - Adipocytes [nTPM]":"19.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"356.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"594.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.1","Single Cell Type RNA - Endothelial cells [nTPM]":"31.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"171.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"516.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3239.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"4.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"ROR1","Gene synonym":["NTRKR1"],"Ensembl":"ENSG00000185483","Gene description":"Receptor tyrosine kinase like orphan receptor 1","Uniprot":["Q01973"],"Chromosome":"1","Position":"63774017-64181498","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Kinase","Receptor","Transferase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"26.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"51.3","Astrocytes":"81.0","Inhibitory neurons":"69.7","Microglial cells":"36.5","Oligodendrocytes":"109.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"40.5","ASC TERT1":"50.3","CACO-2":"36.8","HHSteC":"38.3","HSkMC":"41.6","NTERA-2":"43.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7700000","Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"3.7","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"4.5","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"7.1","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"2.5","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"7.5","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"7.0","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"5.5","Tissue RNA - parathyroid gland [nTPM]":"26.9","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"6.4","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"1.7","Tissue RNA - smooth muscle [nTPM]":"7.7","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"3.2","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"2.5","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"1.6","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"15.5","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"5.9","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"40.5","Cell RNA - ASC TERT1 [nTPM]":"50.3","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"2.9","Cell RNA - BJ hTERT+ [nTPM]":"8.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.3","Cell RNA - CACO-2 [nTPM]":"36.8","Cell RNA - CAPAN-2 [nTPM]":"4.9","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"6.6","Cell RNA - fHDF\/TERT166 [nTPM]":"7.2","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"3.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"3.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.6","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"38.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"41.6","Cell RNA - hTCEpi [nTPM]":"10.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.7","Cell RNA - hTERT-HME1 [nTPM]":"25.2","Cell RNA - hTERT-RPE1 [nTPM]":"8.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"11.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"43.0","Cell RNA - OE19 [nTPM]":"11.3","Cell RNA - PC-3 [nTPM]":"6.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"9.8","Cell RNA - RPTEC TERT1 [nTPM]":"8.7","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"13.6","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"6.4","Cell RNA - SuSa [nTPM]":"19.9","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"8.4","Cell RNA - U-138 MG [nTPM]":"3.3","Cell RNA - U-2 OS [nTPM]":"5.7","Cell RNA - U-2197 [nTPM]":"23.0","Cell RNA - U-251 MG [nTPM]":"6.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.5","Single Cell Type RNA - Astrocytes [nTPM]":"81.0","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.6","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"14.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"69.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.1","Single Cell Type RNA - Leydig cells [nTPM]":"27.7","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"109.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"RORB","Gene synonym":["NR1F2","ROR-BETA","RZRB"],"Ensembl":"ENSG00000198963","Gene description":"RAR related orphan receptor B","Uniprot":["Q92753"],"Chromosome":"9","Position":"74497335-74693177","Protein class":["Disease related genes","Human disease related genes","Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Sensory transduction","Transcription","Transcription regulation","Vision"],"Molecular function":["Activator","Developmental protein","DNA-binding","Receptor"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.0","retina":"55.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"393.7","Endometrial stromal cells":"436.8","Excitatory neurons":"190.0","Horizontal cells":"1399.8","Muller glia cells":"390.7","Rod photoreceptor cells":"190.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"2.1","prostate cancer":"2.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"18.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HHSteC":"22.5","HSkMC":"12.4","JURKAT":"23.3","MOLT-4":"6.9","SH-SY5Y":"13.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008393"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA008393":"AB_1079830"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"3.4","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"18.0","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"2.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"55.6","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"22.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"12.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"23.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"3.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"13.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"3.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"18.0","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"393.7","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"156.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"120.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"436.8","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"190.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1399.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"390.7","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"190.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.9","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"RP1","Gene synonym":["DCDC4A","ORP1"],"Ensembl":"ENSG00000104237","Gene description":"RP1 axonemal microtubule associated","Uniprot":["P56715"],"Chromosome":"8","Position":"54509422-54871720","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"retina":"236.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"333.6","Rod photoreceptor cells":"1115.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"1.6","HDLM-2":"5.2","hTERT-RPE1":"2.0","RPTEC TERT1":"10.2","U-2197":"2.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"1.3"},"Antibody":["HPA042257"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042257":"AB_10797385"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"10.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"3.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"236.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"5.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"2.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"10.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"2.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"72.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"31.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"333.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"81.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"130.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"149.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1115.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"RP1L1","Gene synonym":["DCDC4B"],"Ensembl":"ENSG00000183638","Gene description":"RP1 like 1","Uniprot":["Q8IWN7"],"Chromosome":"8","Position":"10606349-10712187","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"114","RNA tissue specific nTPM":{"retina":"44.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"93.8","Rod photoreceptor cells":"68.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024686","HPA024744"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024686":"AB_2671650","HPA024744":"AB_2671668"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"44.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"93.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"68.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"RP2","Gene synonym":["NM23-H10","NME10","TBCCD2"],"Ensembl":"ENSG00000102218","Gene description":"RP2 activator of ARL3 GTPase","Uniprot":["O75695"],"Chromosome":"X","Position":"46837043-46882358","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["GTPase activation"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"49.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"62.8","Langerhans cells":"72.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000234","HPA000909"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA000234":"AB_1079831","HPA000909":"AB_2666140"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.97e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"8.9","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"15.6","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"49.5","Tissue RNA - breast [nTPM]":"7.2","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"10.1","Tissue RNA - duodenum [nTPM]":"10.6","Tissue RNA - endometrium 1 [nTPM]":"6.9","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"12.9","Tissue RNA - fallopian tube [nTPM]":"6.8","Tissue RNA - gallbladder [nTPM]":"12.7","Tissue RNA - heart muscle [nTPM]":"4.8","Tissue RNA - hippocampal formation [nTPM]":"1.7","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"6.7","Tissue RNA - liver [nTPM]":"13.2","Tissue RNA - lung [nTPM]":"11.8","Tissue RNA - lymph node [nTPM]":"12.9","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"6.5","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"25.2","Tissue RNA - pons [nTPM]":"3.5","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"10.5","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"4.4","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"11.0","Tissue RNA - smooth muscle [nTPM]":"9.0","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"13.2","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"6.1","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"11.2","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"21.8","Cell RNA - A549 [nTPM]":"10.3","Cell RNA - AF22 [nTPM]":"20.4","Cell RNA - AN3-CA [nTPM]":"11.0","Cell RNA - ASC diff [nTPM]":"15.7","Cell RNA - ASC TERT1 [nTPM]":"19.4","Cell RNA - BEWO [nTPM]":"48.0","Cell RNA - BJ [nTPM]":"27.4","Cell RNA - BJ hTERT+ [nTPM]":"21.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.9","Cell RNA - CACO-2 [nTPM]":"44.6","Cell RNA - CAPAN-2 [nTPM]":"18.2","Cell RNA - Daudi [nTPM]":"25.8","Cell RNA - EFO-21 [nTPM]":"10.7","Cell RNA - fHDF\/TERT166 [nTPM]":"29.3","Cell RNA - GAMG [nTPM]":"20.1","Cell RNA - HaCaT [nTPM]":"14.0","Cell RNA - HAP1 [nTPM]":"19.8","Cell RNA - HBEC3-KT [nTPM]":"20.0","Cell RNA - HBF TERT88 [nTPM]":"32.1","Cell RNA - HDLM-2 [nTPM]":"11.5","Cell RNA - HEK 293 [nTPM]":"11.5","Cell RNA - HEL [nTPM]":"13.9","Cell RNA - HeLa [nTPM]":"11.7","Cell RNA - Hep G2 [nTPM]":"10.7","Cell RNA - HHSteC [nTPM]":"17.9","Cell RNA - HL-60 [nTPM]":"29.2","Cell RNA - HMC-1 [nTPM]":"46.4","Cell RNA - HSkMC [nTPM]":"15.1","Cell RNA - hTCEpi [nTPM]":"13.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.8","Cell RNA - hTERT-HME1 [nTPM]":"10.1","Cell RNA - hTERT-RPE1 [nTPM]":"13.3","Cell RNA - HUVEC TERT2 [nTPM]":"30.5","Cell RNA - JURKAT [nTPM]":"11.4","Cell RNA - K-562 [nTPM]":"6.2","Cell RNA - Karpas-707 [nTPM]":"13.1","Cell RNA - LHCN-M2 [nTPM]":"27.0","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"18.1","Cell RNA - NB-4 [nTPM]":"26.8","Cell RNA - NTERA-2 [nTPM]":"12.5","Cell RNA - OE19 [nTPM]":"14.8","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"22.9","Cell RNA - RH-30 [nTPM]":"27.9","Cell RNA - RPMI-8226 [nTPM]":"13.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"22.0","Cell RNA - SCLC-21H [nTPM]":"7.4","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"24.4","Cell RNA - SK-BR-3 [nTPM]":"14.9","Cell RNA - SK-MEL-30 [nTPM]":"12.4","Cell RNA - SuSa [nTPM]":"36.2","Cell RNA - T-47d [nTPM]":"16.8","Cell RNA - THP-1 [nTPM]":"27.1","Cell RNA - TIME [nTPM]":"27.1","Cell RNA - U-138 MG [nTPM]":"18.3","Cell RNA - U-2 OS [nTPM]":"13.6","Cell RNA - U-2197 [nTPM]":"29.1","Cell RNA - U-251 MG [nTPM]":"9.8","Cell RNA - U-266\/70 [nTPM]":"4.9","Cell RNA - U-266\/84 [nTPM]":"6.8","Cell RNA - U-698 [nTPM]":"15.4","Cell RNA - U-87 MG [nTPM]":"9.5","Cell RNA - U-937 [nTPM]":"20.4","Cell RNA - WM-115 [nTPM]":"19.5","Blood RNA - basophil [nTPM]":"62.6","Blood RNA - classical monocyte [nTPM]":"22.6","Blood RNA - eosinophil [nTPM]":"35.5","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"30.8","Blood RNA - MAIT T-cell [nTPM]":"5.0","Blood RNA - memory B-cell [nTPM]":"10.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"22.6","Blood RNA - naive B-cell [nTPM]":"9.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.0","Blood RNA - naive CD8 T-cell [nTPM]":"5.7","Blood RNA - neutrophil [nTPM]":"43.5","Blood RNA - NK-cell [nTPM]":"7.6","Blood RNA - non-classical monocyte [nTPM]":"36.3","Blood RNA - plasmacytoid DC [nTPM]":"7.6","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"12.2","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"1.7","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"3.5","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.4","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"18.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"5.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.2","Single Cell Type RNA - dendritic cells [nTPM]":"12.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.5","Single Cell Type RNA - Endothelial cells [nTPM]":"8.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.9","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"62.8","Single Cell Type RNA - Langerhans cells [nTPM]":"72.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"44.7","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"36.6","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.4","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"13.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.5","Single Cell Type RNA - Spermatocytes [nTPM]":"7.8","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.2","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.5","Single Cell Type RNA - Urothelial cells [nTPM]":"13.6"},{"Gene":"RP9","Gene synonym":["PAP-1"],"Ensembl":"ENSG00000164610","Gene description":"RP9 pre-mRNA splicing factor","Uniprot":["Q8TA86"],"Chromosome":"7","Position":"33094797-33109404","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031523","HPA050778"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA031523":"AB_10603235","HPA050778":"AB_2681233"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.65e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Tissue RNA - adipose tissue [nTPM]":"12.6","Tissue RNA - adrenal gland [nTPM]":"15.0","Tissue RNA - amygdala [nTPM]":"26.3","Tissue RNA - appendix [nTPM]":"8.7","Tissue RNA - basal ganglia [nTPM]":"26.1","Tissue RNA - bone marrow [nTPM]":"21.6","Tissue RNA - breast [nTPM]":"12.6","Tissue RNA - cerebellum [nTPM]":"28.0","Tissue RNA - cerebral cortex [nTPM]":"51.2","Tissue RNA - cervix [nTPM]":"17.0","Tissue RNA - choroid plexus [nTPM]":"26.7","Tissue RNA - colon [nTPM]":"16.7","Tissue RNA - duodenum [nTPM]":"9.0","Tissue RNA - endometrium 1 [nTPM]":"14.4","Tissue RNA - epididymis [nTPM]":"15.5","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"29.2","Tissue RNA - hippocampal formation [nTPM]":"25.8","Tissue RNA - hypothalamus [nTPM]":"26.3","Tissue RNA - kidney [nTPM]":"17.2","Tissue RNA - liver [nTPM]":"13.8","Tissue RNA - lung [nTPM]":"12.0","Tissue RNA - lymph node [nTPM]":"15.6","Tissue RNA - medulla oblongata [nTPM]":"26.6","Tissue RNA - midbrain [nTPM]":"26.3","Tissue RNA - ovary [nTPM]":"16.2","Tissue RNA - pancreas [nTPM]":"20.2","Tissue RNA - parathyroid gland [nTPM]":"10.5","Tissue RNA - pituitary gland [nTPM]":"10.3","Tissue RNA - placenta [nTPM]":"10.2","Tissue RNA - pons [nTPM]":"26.7","Tissue RNA - prostate [nTPM]":"14.4","Tissue RNA - rectum [nTPM]":"9.8","Tissue RNA - retina [nTPM]":"16.7","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"11.7","Tissue RNA - skeletal muscle [nTPM]":"36.3","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"15.9","Tissue RNA - smooth muscle [nTPM]":"8.4","Tissue RNA - spinal cord [nTPM]":"25.8","Tissue RNA - spleen [nTPM]":"20.8","Tissue RNA - stomach 1 [nTPM]":"13.5","Tissue RNA - testis [nTPM]":"18.1","Tissue RNA - thalamus [nTPM]":"26.9","Tissue RNA - thymus [nTPM]":"13.8","Tissue RNA - thyroid gland [nTPM]":"16.0","Tissue RNA - tongue [nTPM]":"34.3","Tissue RNA - tonsil [nTPM]":"16.7","Tissue RNA - urinary bladder [nTPM]":"14.3","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"27.4","Cell RNA - A-431 [nTPM]":"20.9","Cell RNA - A549 [nTPM]":"28.8","Cell RNA - AF22 [nTPM]":"29.7","Cell RNA - AN3-CA [nTPM]":"34.1","Cell RNA - ASC diff [nTPM]":"18.5","Cell RNA - ASC TERT1 [nTPM]":"17.2","Cell RNA - BEWO [nTPM]":"14.3","Cell RNA - BJ [nTPM]":"26.4","Cell RNA - BJ hTERT+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.0","Cell RNA - CACO-2 [nTPM]":"25.6","Cell RNA - CAPAN-2 [nTPM]":"14.6","Cell RNA - Daudi [nTPM]":"26.2","Cell RNA - EFO-21 [nTPM]":"17.0","Cell RNA - fHDF\/TERT166 [nTPM]":"21.1","Cell RNA - GAMG [nTPM]":"35.4","Cell RNA - HaCaT [nTPM]":"20.4","Cell RNA - HAP1 [nTPM]":"36.4","Cell RNA - HBEC3-KT [nTPM]":"22.0","Cell RNA - HBF TERT88 [nTPM]":"36.8","Cell RNA - HDLM-2 [nTPM]":"11.9","Cell RNA - HEK 293 [nTPM]":"25.1","Cell RNA - HEL [nTPM]":"19.2","Cell RNA - HeLa [nTPM]":"22.8","Cell RNA - Hep G2 [nTPM]":"24.4","Cell RNA - HHSteC [nTPM]":"32.4","Cell RNA - HL-60 [nTPM]":"26.0","Cell RNA - HMC-1 [nTPM]":"13.0","Cell RNA - HSkMC [nTPM]":"17.5","Cell RNA - hTCEpi [nTPM]":"20.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.8","Cell RNA - hTERT-HME1 [nTPM]":"64.5","Cell RNA - hTERT-RPE1 [nTPM]":"23.3","Cell RNA - HUVEC TERT2 [nTPM]":"24.0","Cell RNA - JURKAT [nTPM]":"27.1","Cell RNA - K-562 [nTPM]":"35.2","Cell RNA - Karpas-707 [nTPM]":"23.0","Cell RNA - LHCN-M2 [nTPM]":"29.1","Cell RNA - MCF7 [nTPM]":"42.6","Cell RNA - MOLT-4 [nTPM]":"27.7","Cell RNA - NB-4 [nTPM]":"69.6","Cell RNA - NTERA-2 [nTPM]":"25.4","Cell RNA - OE19 [nTPM]":"27.2","Cell RNA - PC-3 [nTPM]":"21.9","Cell RNA - REH [nTPM]":"28.2","Cell RNA - RH-30 [nTPM]":"26.4","Cell RNA - RPMI-8226 [nTPM]":"17.1","Cell RNA - RPTEC TERT1 [nTPM]":"21.1","Cell RNA - RT4 [nTPM]":"19.3","Cell RNA - SCLC-21H [nTPM]":"28.7","Cell RNA - SH-SY5Y [nTPM]":"39.5","Cell RNA - SiHa [nTPM]":"18.7","Cell RNA - SK-BR-3 [nTPM]":"39.6","Cell RNA - SK-MEL-30 [nTPM]":"46.2","Cell RNA - SuSa [nTPM]":"35.1","Cell RNA - T-47d [nTPM]":"20.8","Cell RNA - THP-1 [nTPM]":"35.0","Cell RNA - TIME [nTPM]":"19.4","Cell RNA - U-138 MG [nTPM]":"28.4","Cell RNA - U-2 OS [nTPM]":"40.9","Cell RNA - U-2197 [nTPM]":"25.6","Cell RNA - U-251 MG [nTPM]":"42.8","Cell RNA - U-266\/70 [nTPM]":"38.1","Cell RNA - U-266\/84 [nTPM]":"37.2","Cell RNA - U-698 [nTPM]":"51.7","Cell RNA - U-87 MG [nTPM]":"20.0","Cell RNA - U-937 [nTPM]":"36.3","Cell RNA - WM-115 [nTPM]":"56.1","Blood RNA - basophil [nTPM]":"21.9","Blood RNA - classical monocyte [nTPM]":"12.0","Blood RNA - eosinophil [nTPM]":"21.6","Blood RNA - gdT-cell [nTPM]":"15.2","Blood RNA - intermediate monocyte [nTPM]":"9.8","Blood RNA - MAIT T-cell [nTPM]":"14.1","Blood RNA - memory B-cell [nTPM]":"57.8","Blood RNA - memory CD4 T-cell [nTPM]":"16.3","Blood RNA - memory CD8 T-cell [nTPM]":"17.4","Blood RNA - myeloid DC [nTPM]":"13.2","Blood RNA - naive B-cell [nTPM]":"77.3","Blood RNA - naive CD4 T-cell [nTPM]":"19.1","Blood RNA - naive CD8 T-cell [nTPM]":"18.0","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"15.7","Blood RNA - non-classical monocyte [nTPM]":"12.5","Blood RNA - plasmacytoid DC [nTPM]":"28.4","Blood RNA - T-reg [nTPM]":"15.8","Blood RNA - total PBMC [nTPM]":"8.8","Brain RNA - amygdala [nTPM]":"26.3","Brain RNA - basal ganglia [nTPM]":"26.1","Brain RNA - cerebellum [nTPM]":"28.0","Brain RNA - cerebral cortex [nTPM]":"51.2","Brain RNA - hippocampal formation [nTPM]":"25.8","Brain RNA - hypothalamus [nTPM]":"26.3","Brain RNA - medulla oblongata [nTPM]":"26.6","Brain RNA - midbrain [nTPM]":"26.3","Brain RNA - pons [nTPM]":"26.7","Brain RNA - spinal cord [nTPM]":"25.8","Brain RNA - thalamus [nTPM]":"26.9","Brain RNA - white matter [nTPM]":"27.4","Single Cell Type RNA - Adipocytes [nTPM]":"21.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"35.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.2","Single Cell Type RNA - dendritic cells [nTPM]":"16.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"16.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.2","Single Cell Type RNA - Endothelial cells [nTPM]":"24.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.0","Single Cell Type RNA - Fibroblasts [nTPM]":"20.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"26.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"16.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.3","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"14.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"12.0","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"10.1","Single Cell Type RNA - Muller glia cells [nTPM]":"21.9","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.6","Single Cell Type RNA - Paneth cells [nTPM]":"8.0","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"24.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.3","Single Cell Type RNA - Spermatocytes [nTPM]":"31.6","Single Cell Type RNA - Spermatogonia [nTPM]":"54.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - T-cells [nTPM]":"19.9","Single Cell Type RNA - Theca cells [nTPM]":"22.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.0"},{"Gene":"RPE65","Gene synonym":["BCO3","LCA2","rd12","RP20"],"Ensembl":"ENSG00000116745","Gene description":"Retinoid isomerohydrolase RPE65","Uniprot":["Q16518"],"Chromosome":"1","Position":"68428822-68449954","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Hydrolase","Isomerase"],"Disease involvement":["Disease variant","FDA approved drug targets","Leber congenital amaurosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.2","choroid plexus":"4.5","retina":"8.4","seminal vesicle":"4.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"10.4","Rod photoreceptor cells":"17.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"glioma":"5.8","head and neck cancer":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"3.4","PC-3":"5.6","U-2 OS":"1.3"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"amygdala":"3.2","basal ganglia":"2.5","cerebral cortex":"3.9","hippocampal formation":"2.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.75e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"3.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"8.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.3","Cell RNA - A-431 [nTPM]":"3.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"5.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"3.0","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"1.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RPGR","Gene synonym":["COD1","CORDX1","CRD","RP15","RP3"],"Ensembl":"ENSG00000156313","Gene description":"Retinitis pigmentosa GTPase regulator","Uniprot":["Q92834"],"Chromosome":"X","Position":"38269163-38327544","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation","Sensory transduction","Vision"],"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Cancer-related genes","Ciliopathy","Cone-rod dystrophy","Deafness","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"146.1","Hepatic stellate cells":"121.7","Respiratory ciliated cells":"119.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"14.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"14.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"31.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001593","HPA073455"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA001593":"AB_1079835","HPA073455":"AB_2686603"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Tissue RNA - adipose tissue [nTPM]":"19.2","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"4.7","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"12.2","Tissue RNA - breast [nTPM]":"16.8","Tissue RNA - cerebellum [nTPM]":"5.2","Tissue RNA - cerebral cortex [nTPM]":"5.5","Tissue RNA - cervix [nTPM]":"10.2","Tissue RNA - choroid plexus [nTPM]":"15.5","Tissue RNA - colon [nTPM]":"9.1","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"11.6","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"15.0","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"9.8","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"3.7","Tissue RNA - lung [nTPM]":"14.8","Tissue RNA - lymph node [nTPM]":"3.7","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"32.9","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"5.8","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"12.1","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"9.4","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"5.1","Tissue RNA - stomach 1 [nTPM]":"6.8","Tissue RNA - testis [nTPM]":"8.1","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"9.7","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"8.2","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"6.0","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"3.2","Cell RNA - ASC diff [nTPM]":"3.6","Cell RNA - ASC TERT1 [nTPM]":"5.2","Cell RNA - BEWO [nTPM]":"2.7","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"6.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.8","Cell RNA - CACO-2 [nTPM]":"2.7","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"7.1","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"3.9","Cell RNA - GAMG [nTPM]":"3.4","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"4.1","Cell RNA - HBEC3-KT [nTPM]":"1.8","Cell RNA - HBF TERT88 [nTPM]":"5.6","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"7.9","Cell RNA - HEL [nTPM]":"2.5","Cell RNA - HeLa [nTPM]":"2.7","Cell RNA - Hep G2 [nTPM]":"5.5","Cell RNA - HHSteC [nTPM]":"3.3","Cell RNA - HL-60 [nTPM]":"31.8","Cell RNA - HMC-1 [nTPM]":"5.8","Cell RNA - HSkMC [nTPM]":"8.0","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.7","Cell RNA - hTERT-HME1 [nTPM]":"9.2","Cell RNA - hTERT-RPE1 [nTPM]":"1.6","Cell RNA - HUVEC TERT2 [nTPM]":"18.9","Cell RNA - JURKAT [nTPM]":"7.5","Cell RNA - K-562 [nTPM]":"3.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"5.7","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"9.1","Cell RNA - NB-4 [nTPM]":"17.7","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"7.5","Cell RNA - REH [nTPM]":"6.8","Cell RNA - RH-30 [nTPM]":"11.7","Cell RNA - RPMI-8226 [nTPM]":"6.4","Cell RNA - RPTEC TERT1 [nTPM]":"3.6","Cell RNA - RT4 [nTPM]":"3.0","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"5.2","Cell RNA - SiHa [nTPM]":"6.4","Cell RNA - SK-BR-3 [nTPM]":"2.6","Cell RNA - SK-MEL-30 [nTPM]":"7.2","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"22.4","Cell RNA - U-138 MG [nTPM]":"4.5","Cell RNA - U-2 OS [nTPM]":"8.0","Cell RNA - U-2197 [nTPM]":"10.7","Cell RNA - U-251 MG [nTPM]":"7.2","Cell RNA - U-266\/70 [nTPM]":"1.9","Cell RNA - U-266\/84 [nTPM]":"3.9","Cell RNA - U-698 [nTPM]":"6.0","Cell RNA - U-87 MG [nTPM]":"10.6","Cell RNA - U-937 [nTPM]":"6.1","Cell RNA - WM-115 [nTPM]":"6.2","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"14.6","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"4.7","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"5.2","Brain RNA - cerebral cortex [nTPM]":"5.5","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"5.8","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"75.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.6","Single Cell Type RNA - Astrocytes [nTPM]":"21.2","Single Cell Type RNA - B-cells [nTPM]":"21.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"29.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"18.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.8","Single Cell Type RNA - dendritic cells [nTPM]":"14.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.3","Single Cell Type RNA - Early spermatids [nTPM]":"51.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"146.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.4","Single Cell Type RNA - Endothelial cells [nTPM]":"61.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.5","Single Cell Type RNA - Fibroblasts [nTPM]":"11.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.0","Single Cell Type RNA - granulocytes [nTPM]":"20.3","Single Cell Type RNA - Granulosa cells [nTPM]":"73.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"121.7","Single Cell Type RNA - Hepatocytes [nTPM]":"9.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.8","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.2","Single Cell Type RNA - Langerhans cells [nTPM]":"8.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.1","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"14.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"15.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.4","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.9","Single Cell Type RNA - Paneth cells [nTPM]":"8.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"11.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"119.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"85.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"24.9","Single Cell Type RNA - Spermatogonia [nTPM]":"25.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - T-cells [nTPM]":"17.2","Single Cell Type RNA - Theca cells [nTPM]":"6.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.9","Single Cell Type RNA - Urothelial cells [nTPM]":"11.2"},{"Gene":"RPGRIP1","Gene synonym":["CORD13","LCA6","RGI1","RPGRIP"],"Ensembl":"ENSG00000092200","Gene description":"RPGR interacting protein 1","Uniprot":["Q96KN7"],"Chromosome":"14","Position":"21280083-21351301","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Ciliopathy","Cone-rod dystrophy","Disease variant","Glaucoma","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"80","RNA tissue specific nTPM":{"retina":"185.3","testis":"59.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"231.4","Early spermatids":"177.3","Late spermatids":"108.9","Rod photoreceptor cells":"117.5","Spermatocytes":"51.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"testis cancer":"1.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"8.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"dendritic cells":"3.3","granulocytes":"8.8","monocytes":"3.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RT4":"3.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042955","HPA060190"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042955":"AB_2678239","HPA060190":"AB_2684218"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"185.3","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"1.5","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"59.6","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.8","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"3.3","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"8.8","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"231.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"177.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"108.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"4.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"117.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"51.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"RRM2B","Gene synonym":["p53R2"],"Ensembl":"ENSG00000048392","Gene description":"Ribonucleotide reductase regulatory TP53 inducible subunit M2B","Uniprot":["Q7LG56"],"Chromosome":"8","Position":"102204502-102238961","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair","DNA replication"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","FDA approved drug targets","Neuropathy","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006854","HPA028812"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB006854":null,"HPA028812":"AB_10602246"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.5","Tissue RNA - adrenal gland [nTPM]":"21.2","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"12.1","Tissue RNA - bone marrow [nTPM]":"7.1","Tissue RNA - breast [nTPM]":"12.1","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"11.5","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"26.5","Tissue RNA - colon [nTPM]":"15.3","Tissue RNA - duodenum [nTPM]":"15.0","Tissue RNA - endometrium 1 [nTPM]":"11.6","Tissue RNA - epididymis [nTPM]":"15.1","Tissue RNA - esophagus [nTPM]":"11.2","Tissue RNA - fallopian tube [nTPM]":"13.5","Tissue RNA - gallbladder [nTPM]":"11.9","Tissue RNA - heart muscle [nTPM]":"16.7","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"13.7","Tissue RNA - kidney [nTPM]":"24.4","Tissue RNA - liver [nTPM]":"22.6","Tissue RNA - lung [nTPM]":"22.0","Tissue RNA - lymph node [nTPM]":"20.1","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"12.4","Tissue RNA - ovary [nTPM]":"12.0","Tissue RNA - pancreas [nTPM]":"13.5","Tissue RNA - parathyroid gland [nTPM]":"45.0","Tissue RNA - pituitary gland [nTPM]":"10.3","Tissue RNA - placenta [nTPM]":"13.8","Tissue RNA - pons [nTPM]":"13.9","Tissue RNA - prostate [nTPM]":"15.7","Tissue RNA - rectum [nTPM]":"15.5","Tissue RNA - retina [nTPM]":"21.9","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"13.8","Tissue RNA - skeletal muscle [nTPM]":"30.4","Tissue RNA - skin 1 [nTPM]":"11.0","Tissue RNA - small intestine [nTPM]":"10.1","Tissue RNA - smooth muscle [nTPM]":"11.7","Tissue RNA - spinal cord [nTPM]":"14.1","Tissue RNA - spleen [nTPM]":"14.3","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"9.7","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"39.9","Tissue RNA - tongue [nTPM]":"34.9","Tissue RNA - tonsil [nTPM]":"19.6","Tissue RNA - urinary bladder [nTPM]":"11.2","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"16.8","Cell RNA - A-431 [nTPM]":"15.3","Cell RNA - A549 [nTPM]":"26.5","Cell RNA - AF22 [nTPM]":"30.7","Cell RNA - AN3-CA [nTPM]":"18.3","Cell RNA - ASC diff [nTPM]":"43.7","Cell RNA - ASC TERT1 [nTPM]":"41.3","Cell RNA - BEWO [nTPM]":"24.6","Cell RNA - BJ [nTPM]":"34.8","Cell RNA - BJ hTERT+ [nTPM]":"41.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.0","Cell RNA - CACO-2 [nTPM]":"9.6","Cell RNA - CAPAN-2 [nTPM]":"11.9","Cell RNA - Daudi [nTPM]":"97.5","Cell RNA - EFO-21 [nTPM]":"31.8","Cell RNA - fHDF\/TERT166 [nTPM]":"38.7","Cell RNA - GAMG [nTPM]":"18.5","Cell RNA - HaCaT [nTPM]":"5.7","Cell RNA - HAP1 [nTPM]":"15.1","Cell RNA - HBEC3-KT [nTPM]":"35.2","Cell RNA - HBF TERT88 [nTPM]":"25.3","Cell RNA - HDLM-2 [nTPM]":"15.8","Cell RNA - HEK 293 [nTPM]":"16.2","Cell RNA - HEL [nTPM]":"24.4","Cell RNA - HeLa [nTPM]":"10.3","Cell RNA - Hep G2 [nTPM]":"20.9","Cell RNA - HHSteC [nTPM]":"35.3","Cell RNA - HL-60 [nTPM]":"7.6","Cell RNA - HMC-1 [nTPM]":"50.0","Cell RNA - HSkMC [nTPM]":"53.1","Cell RNA - hTCEpi [nTPM]":"66.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.2","Cell RNA - hTERT-HME1 [nTPM]":"30.5","Cell RNA - hTERT-RPE1 [nTPM]":"43.0","Cell RNA - HUVEC TERT2 [nTPM]":"51.8","Cell RNA - JURKAT [nTPM]":"16.3","Cell RNA - K-562 [nTPM]":"18.2","Cell RNA - Karpas-707 [nTPM]":"14.6","Cell RNA - LHCN-M2 [nTPM]":"59.1","Cell RNA - MCF7 [nTPM]":"15.2","Cell RNA - MOLT-4 [nTPM]":"13.1","Cell RNA - NB-4 [nTPM]":"14.6","Cell RNA - NTERA-2 [nTPM]":"17.7","Cell RNA - OE19 [nTPM]":"16.5","Cell RNA - PC-3 [nTPM]":"19.2","Cell RNA - REH [nTPM]":"8.2","Cell RNA - RH-30 [nTPM]":"12.7","Cell RNA - RPMI-8226 [nTPM]":"20.1","Cell RNA - RPTEC TERT1 [nTPM]":"43.1","Cell RNA - RT4 [nTPM]":"17.1","Cell RNA - SCLC-21H [nTPM]":"7.8","Cell RNA - SH-SY5Y [nTPM]":"15.4","Cell RNA - SiHa [nTPM]":"17.9","Cell RNA - SK-BR-3 [nTPM]":"9.7","Cell RNA - SK-MEL-30 [nTPM]":"21.1","Cell RNA - SuSa [nTPM]":"76.3","Cell RNA - T-47d [nTPM]":"25.5","Cell RNA - THP-1 [nTPM]":"17.1","Cell RNA - TIME [nTPM]":"39.4","Cell RNA - U-138 MG [nTPM]":"27.8","Cell RNA - U-2 OS [nTPM]":"53.7","Cell RNA - U-2197 [nTPM]":"19.6","Cell RNA - U-251 MG [nTPM]":"9.6","Cell RNA - U-266\/70 [nTPM]":"15.3","Cell RNA - U-266\/84 [nTPM]":"15.3","Cell RNA - U-698 [nTPM]":"88.0","Cell RNA - U-87 MG [nTPM]":"41.0","Cell RNA - U-937 [nTPM]":"11.5","Cell RNA - WM-115 [nTPM]":"30.2","Blood RNA - basophil [nTPM]":"15.7","Blood RNA - classical monocyte [nTPM]":"6.3","Blood RNA - eosinophil [nTPM]":"7.0","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"5.4","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"6.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"7.7","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.8","Blood RNA - neutrophil [nTPM]":"23.1","Blood RNA - NK-cell [nTPM]":"4.1","Blood RNA - non-classical monocyte [nTPM]":"11.5","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"12.1","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"11.5","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"13.7","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"12.4","Brain RNA - pons [nTPM]":"13.9","Brain RNA - spinal cord [nTPM]":"14.1","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"16.8","Single Cell Type RNA - Adipocytes [nTPM]":"16.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"33.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"13.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"23.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - dendritic cells [nTPM]":"13.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"6.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.1","Single Cell Type RNA - Endothelial cells [nTPM]":"14.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"29.4","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.8","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"11.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.5","Single Cell Type RNA - Hepatocytes [nTPM]":"23.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.6","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"26.2","Single Cell Type RNA - Langerhans cells [nTPM]":"39.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"23.8","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"18.2","Single Cell Type RNA - Muller glia cells [nTPM]":"24.5","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.7","Single Cell Type RNA - Paneth cells [nTPM]":"5.7","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.8","Single Cell Type RNA - Spermatocytes [nTPM]":"13.2","Single Cell Type RNA - Spermatogonia [nTPM]":"14.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - T-cells [nTPM]":"12.2","Single Cell Type RNA - Theca cells [nTPM]":"8.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.7"},{"Gene":"RTN2","Gene synonym":["NSP2","NSPL1","SPG12"],"Ensembl":"ENSG00000125744","Gene description":"Reticulon 2","Uniprot":["O75298"],"Chromosome":"19","Position":"45485294-45497055","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"skeletal muscle":"509.8","tongue":"207.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"134.3","Extravillous trophoblasts":"145.7","Skeletal myocytes":"73.2","Syncytiotrophoblasts":"120.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"6.2","eosinophil":"2.6","plasmacytoid DC":"1.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"1.6","granulocytes":"6.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"44.3","RT4":"45.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034941","HPA034948"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA034941":"AB_10671358","HPA034948":"AB_2674375"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"21.4","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"25.7","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"12.0","Tissue RNA - cerebellum [nTPM]":"15.9","Tissue RNA - cerebral cortex [nTPM]":"43.6","Tissue RNA - cervix [nTPM]":"5.9","Tissue RNA - choroid plexus [nTPM]":"7.8","Tissue RNA - colon [nTPM]":"21.8","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"15.2","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"12.1","Tissue RNA - fallopian tube [nTPM]":"4.6","Tissue RNA - gallbladder [nTPM]":"7.9","Tissue RNA - heart muscle [nTPM]":"21.9","Tissue RNA - hippocampal formation [nTPM]":"24.7","Tissue RNA - hypothalamus [nTPM]":"22.0","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"8.2","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"27.3","Tissue RNA - midbrain [nTPM]":"19.3","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"10.1","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"19.2","Tissue RNA - pons [nTPM]":"27.0","Tissue RNA - prostate [nTPM]":"17.0","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"22.3","Tissue RNA - seminal vesicle [nTPM]":"10.6","Tissue RNA - skeletal muscle [nTPM]":"509.8","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"8.7","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"14.1","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"7.9","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"25.1","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"207.7","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"7.8","Tissue RNA - white matter [nTPM]":"29.0","Cell RNA - A-431 [nTPM]":"3.8","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"8.6","Cell RNA - AN3-CA [nTPM]":"6.7","Cell RNA - ASC diff [nTPM]":"14.4","Cell RNA - ASC TERT1 [nTPM]":"17.6","Cell RNA - BEWO [nTPM]":"16.9","Cell RNA - BJ [nTPM]":"8.5","Cell RNA - BJ hTERT+ [nTPM]":"20.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.9","Cell RNA - CACO-2 [nTPM]":"10.4","Cell RNA - CAPAN-2 [nTPM]":"3.2","Cell RNA - Daudi [nTPM]":"3.3","Cell RNA - EFO-21 [nTPM]":"11.4","Cell RNA - fHDF\/TERT166 [nTPM]":"9.3","Cell RNA - GAMG [nTPM]":"4.2","Cell RNA - HaCaT [nTPM]":"7.2","Cell RNA - HAP1 [nTPM]":"5.6","Cell RNA - HBEC3-KT [nTPM]":"4.1","Cell RNA - HBF TERT88 [nTPM]":"1.7","Cell RNA - HDLM-2 [nTPM]":"7.9","Cell RNA - HEK 293 [nTPM]":"8.2","Cell RNA - HEL [nTPM]":"23.0","Cell RNA - HeLa [nTPM]":"3.9","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"6.2","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"25.0","Cell RNA - HSkMC [nTPM]":"19.5","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.3","Cell RNA - hTERT-HME1 [nTPM]":"4.2","Cell RNA - hTERT-RPE1 [nTPM]":"9.2","Cell RNA - HUVEC TERT2 [nTPM]":"9.6","Cell RNA - JURKAT [nTPM]":"0.9","Cell RNA - K-562 [nTPM]":"12.9","Cell RNA - Karpas-707 [nTPM]":"6.2","Cell RNA - LHCN-M2 [nTPM]":"15.6","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"4.3","Cell RNA - NTERA-2 [nTPM]":"6.3","Cell RNA - OE19 [nTPM]":"17.0","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"3.6","Cell RNA - RH-30 [nTPM]":"44.3","Cell RNA - RPMI-8226 [nTPM]":"18.8","Cell RNA - RPTEC TERT1 [nTPM]":"3.0","Cell RNA - RT4 [nTPM]":"45.0","Cell RNA - SCLC-21H [nTPM]":"24.1","Cell RNA - SH-SY5Y [nTPM]":"23.1","Cell RNA - SiHa [nTPM]":"1.7","Cell RNA - SK-BR-3 [nTPM]":"40.7","Cell RNA - SK-MEL-30 [nTPM]":"13.2","Cell RNA - SuSa [nTPM]":"8.0","Cell RNA - T-47d [nTPM]":"32.3","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"8.6","Cell RNA - U-138 MG [nTPM]":"14.7","Cell RNA - U-2 OS [nTPM]":"4.4","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"1.9","Cell RNA - U-266\/70 [nTPM]":"3.5","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"7.7","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"5.2","Cell RNA - WM-115 [nTPM]":"7.7","Blood RNA - basophil [nTPM]":"6.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"21.4","Brain RNA - basal ganglia [nTPM]":"25.7","Brain RNA - cerebellum [nTPM]":"15.9","Brain RNA - cerebral cortex [nTPM]":"43.6","Brain RNA - hippocampal formation [nTPM]":"24.7","Brain RNA - hypothalamus [nTPM]":"22.0","Brain RNA - medulla oblongata [nTPM]":"27.3","Brain RNA - midbrain [nTPM]":"19.3","Brain RNA - pons [nTPM]":"27.0","Brain RNA - spinal cord [nTPM]":"14.1","Brain RNA - thalamus [nTPM]":"25.1","Brain RNA - white matter [nTPM]":"29.0","Single Cell Type RNA - Adipocytes [nTPM]":"9.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"10.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"134.3","Single Cell Type RNA - dendritic cells [nTPM]":"2.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"21.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"15.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"145.7","Single Cell Type RNA - Fibroblasts [nTPM]":"14.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"3.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.3","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.9","Single Cell Type RNA - Langerhans cells [nTPM]":"12.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"10.7","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"6.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"2.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"73.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"120.1","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"16.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"23.2"},{"Gene":"RTN4IP1","Gene synonym":["NIMP"],"Ensembl":"ENSG00000130347","Gene description":"Reticulon 4 interacting protein 1","Uniprot":["Q8WWV3"],"Chromosome":"6","Position":"106570771-106629498","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Neurogenesis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"27.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036357"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036357":"AB_10673128"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.18e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.55e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.5","Tissue RNA - adrenal gland [nTPM]":"6.8","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"3.2","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"2.6","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"6.3","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"2.7","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"4.2","Tissue RNA - fallopian tube [nTPM]":"2.7","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"14.7","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"7.4","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"2.2","Tissue RNA - pons [nTPM]":"2.8","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"2.7","Tissue RNA - skeletal muscle [nTPM]":"15.6","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"4.0","Tissue RNA - tongue [nTPM]":"15.4","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"2.9","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"7.6","Cell RNA - A549 [nTPM]":"10.8","Cell RNA - AF22 [nTPM]":"7.3","Cell RNA - AN3-CA [nTPM]":"12.6","Cell RNA - ASC diff [nTPM]":"5.9","Cell RNA - ASC TERT1 [nTPM]":"3.5","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"5.0","Cell RNA - BJ hTERT+ [nTPM]":"7.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.4","Cell RNA - CACO-2 [nTPM]":"17.4","Cell RNA - CAPAN-2 [nTPM]":"4.1","Cell RNA - Daudi [nTPM]":"11.6","Cell RNA - EFO-21 [nTPM]":"7.6","Cell RNA - fHDF\/TERT166 [nTPM]":"6.5","Cell RNA - GAMG [nTPM]":"15.1","Cell RNA - HaCaT [nTPM]":"10.8","Cell RNA - HAP1 [nTPM]":"13.0","Cell RNA - HBEC3-KT [nTPM]":"10.7","Cell RNA - HBF TERT88 [nTPM]":"12.1","Cell RNA - HDLM-2 [nTPM]":"8.1","Cell RNA - HEK 293 [nTPM]":"7.4","Cell RNA - HEL [nTPM]":"12.1","Cell RNA - HeLa [nTPM]":"8.4","Cell RNA - Hep G2 [nTPM]":"14.0","Cell RNA - HHSteC [nTPM]":"6.1","Cell RNA - HL-60 [nTPM]":"12.5","Cell RNA - HMC-1 [nTPM]":"8.1","Cell RNA - HSkMC [nTPM]":"5.2","Cell RNA - hTCEpi [nTPM]":"8.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.3","Cell RNA - hTERT-HME1 [nTPM]":"6.7","Cell RNA - hTERT-RPE1 [nTPM]":"4.7","Cell RNA - HUVEC TERT2 [nTPM]":"6.9","Cell RNA - JURKAT [nTPM]":"16.3","Cell RNA - K-562 [nTPM]":"21.7","Cell RNA - Karpas-707 [nTPM]":"4.7","Cell RNA - LHCN-M2 [nTPM]":"8.5","Cell RNA - MCF7 [nTPM]":"11.3","Cell RNA - MOLT-4 [nTPM]":"4.7","Cell RNA - NB-4 [nTPM]":"14.4","Cell RNA - NTERA-2 [nTPM]":"9.1","Cell RNA - OE19 [nTPM]":"10.7","Cell RNA - PC-3 [nTPM]":"7.9","Cell RNA - REH [nTPM]":"16.1","Cell RNA - RH-30 [nTPM]":"13.3","Cell RNA - RPMI-8226 [nTPM]":"8.8","Cell RNA - RPTEC TERT1 [nTPM]":"12.4","Cell RNA - RT4 [nTPM]":"8.1","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"5.7","Cell RNA - SiHa [nTPM]":"4.7","Cell RNA - SK-BR-3 [nTPM]":"12.3","Cell RNA - SK-MEL-30 [nTPM]":"11.2","Cell RNA - SuSa [nTPM]":"7.5","Cell RNA - T-47d [nTPM]":"15.5","Cell RNA - THP-1 [nTPM]":"8.0","Cell RNA - TIME [nTPM]":"3.6","Cell RNA - U-138 MG [nTPM]":"4.4","Cell RNA - U-2 OS [nTPM]":"6.1","Cell RNA - U-2197 [nTPM]":"8.8","Cell RNA - U-251 MG [nTPM]":"8.9","Cell RNA - U-266\/70 [nTPM]":"3.5","Cell RNA - U-266\/84 [nTPM]":"5.7","Cell RNA - U-698 [nTPM]":"24.8","Cell RNA - U-87 MG [nTPM]":"11.5","Cell RNA - U-937 [nTPM]":"18.1","Cell RNA - WM-115 [nTPM]":"9.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"4.6","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"5.1","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"11.4","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"10.7","Blood RNA - naive B-cell [nTPM]":"16.0","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.9","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"6.5","Blood RNA - non-classical monocyte [nTPM]":"3.7","Blood RNA - plasmacytoid DC [nTPM]":"5.6","Blood RNA - T-reg [nTPM]":"8.2","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"2.8","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"8.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"6.7","Single Cell Type RNA - Early spermatids [nTPM]":"8.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"5.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"3.7","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.9","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.5","Single Cell Type RNA - Spermatocytes [nTPM]":"11.9","Single Cell Type RNA - Spermatogonia [nTPM]":"16.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"5.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"RUBCN","Gene synonym":["KIAA0226","rubicon","rundataxin"],"Ensembl":"ENSG00000145016","Gene description":"Rubicon autophagy regulator","Uniprot":["Q92622"],"Chromosome":"3","Position":"197668867-197749727","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy","Endocytosis","Immunity","Phagocytosis"],"Molecular function":null,"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"67.5","Plasma cells":"48.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"87.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050908","HPA054497"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA050908":null,"HPA054497":"AB_2682507"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.65e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.91e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.3","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"16.2","Tissue RNA - appendix [nTPM]":"11.6","Tissue RNA - basal ganglia [nTPM]":"16.3","Tissue RNA - bone marrow [nTPM]":"8.5","Tissue RNA - breast [nTPM]":"7.2","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"17.0","Tissue RNA - cervix [nTPM]":"9.2","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"10.4","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"7.2","Tissue RNA - heart muscle [nTPM]":"11.4","Tissue RNA - hippocampal formation [nTPM]":"17.0","Tissue RNA - hypothalamus [nTPM]":"19.0","Tissue RNA - kidney [nTPM]":"7.7","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"11.8","Tissue RNA - lymph node [nTPM]":"15.3","Tissue RNA - medulla oblongata [nTPM]":"20.0","Tissue RNA - midbrain [nTPM]":"17.8","Tissue RNA - ovary [nTPM]":"10.7","Tissue RNA - pancreas [nTPM]":"9.1","Tissue RNA - parathyroid gland [nTPM]":"6.8","Tissue RNA - pituitary gland [nTPM]":"15.8","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"15.9","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"5.7","Tissue RNA - retina [nTPM]":"10.9","Tissue RNA - salivary gland [nTPM]":"7.3","Tissue RNA - seminal vesicle [nTPM]":"7.2","Tissue RNA - skeletal muscle [nTPM]":"8.9","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"13.1","Tissue RNA - smooth muscle [nTPM]":"7.8","Tissue RNA - spinal cord [nTPM]":"14.5","Tissue RNA - spleen [nTPM]":"19.2","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"14.6","Tissue RNA - thalamus [nTPM]":"23.7","Tissue RNA - thymus [nTPM]":"8.8","Tissue RNA - thyroid gland [nTPM]":"7.1","Tissue RNA - tongue [nTPM]":"8.1","Tissue RNA - tonsil [nTPM]":"16.1","Tissue RNA - urinary bladder [nTPM]":"8.9","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"17.4","Cell RNA - A-431 [nTPM]":"30.9","Cell RNA - A549 [nTPM]":"7.4","Cell RNA - AF22 [nTPM]":"8.2","Cell RNA - AN3-CA [nTPM]":"16.2","Cell RNA - ASC diff [nTPM]":"14.4","Cell RNA - ASC TERT1 [nTPM]":"8.3","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"13.8","Cell RNA - BJ hTERT+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.2","Cell RNA - CACO-2 [nTPM]":"12.7","Cell RNA - CAPAN-2 [nTPM]":"8.4","Cell RNA - Daudi [nTPM]":"33.6","Cell RNA - EFO-21 [nTPM]":"26.7","Cell RNA - fHDF\/TERT166 [nTPM]":"15.8","Cell RNA - GAMG [nTPM]":"16.1","Cell RNA - HaCaT [nTPM]":"17.0","Cell RNA - HAP1 [nTPM]":"15.0","Cell RNA - HBEC3-KT [nTPM]":"8.0","Cell RNA - HBF TERT88 [nTPM]":"13.6","Cell RNA - HDLM-2 [nTPM]":"9.3","Cell RNA - HEK 293 [nTPM]":"13.9","Cell RNA - HEL [nTPM]":"21.6","Cell RNA - HeLa [nTPM]":"13.4","Cell RNA - Hep G2 [nTPM]":"4.9","Cell RNA - HHSteC [nTPM]":"8.4","Cell RNA - HL-60 [nTPM]":"12.0","Cell RNA - HMC-1 [nTPM]":"18.0","Cell RNA - HSkMC [nTPM]":"7.0","Cell RNA - hTCEpi [nTPM]":"9.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.8","Cell RNA - hTERT-HME1 [nTPM]":"17.6","Cell RNA - hTERT-RPE1 [nTPM]":"7.9","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"14.4","Cell RNA - K-562 [nTPM]":"12.3","Cell RNA - Karpas-707 [nTPM]":"87.7","Cell RNA - LHCN-M2 [nTPM]":"11.5","Cell RNA - MCF7 [nTPM]":"24.4","Cell RNA - MOLT-4 [nTPM]":"15.7","Cell RNA - NB-4 [nTPM]":"7.5","Cell RNA - NTERA-2 [nTPM]":"7.1","Cell RNA - OE19 [nTPM]":"8.8","Cell RNA - PC-3 [nTPM]":"23.2","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"8.6","Cell RNA - RPMI-8226 [nTPM]":"22.6","Cell RNA - RPTEC TERT1 [nTPM]":"9.6","Cell RNA - RT4 [nTPM]":"13.9","Cell RNA - SCLC-21H [nTPM]":"34.3","Cell RNA - SH-SY5Y [nTPM]":"7.9","Cell RNA - SiHa [nTPM]":"10.2","Cell RNA - SK-BR-3 [nTPM]":"19.8","Cell RNA - SK-MEL-30 [nTPM]":"10.8","Cell RNA - SuSa [nTPM]":"5.5","Cell RNA - T-47d [nTPM]":"29.2","Cell RNA - THP-1 [nTPM]":"8.1","Cell RNA - TIME [nTPM]":"13.7","Cell RNA - U-138 MG [nTPM]":"9.9","Cell RNA - U-2 OS [nTPM]":"9.9","Cell RNA - U-2197 [nTPM]":"27.8","Cell RNA - U-251 MG [nTPM]":"18.9","Cell RNA - U-266\/70 [nTPM]":"36.5","Cell RNA - U-266\/84 [nTPM]":"34.2","Cell RNA - U-698 [nTPM]":"27.0","Cell RNA - U-87 MG [nTPM]":"13.6","Cell RNA - U-937 [nTPM]":"22.4","Cell RNA - WM-115 [nTPM]":"8.7","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"17.5","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"7.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.1","Blood RNA - memory CD8 T-cell [nTPM]":"4.7","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"8.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"4.8","Blood RNA - plasmacytoid DC [nTPM]":"16.6","Blood RNA - T-reg [nTPM]":"4.4","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"16.2","Brain RNA - basal ganglia [nTPM]":"16.3","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"17.0","Brain RNA - hippocampal formation [nTPM]":"17.0","Brain RNA - hypothalamus [nTPM]":"19.0","Brain RNA - medulla oblongata [nTPM]":"20.0","Brain RNA - midbrain [nTPM]":"17.8","Brain RNA - pons [nTPM]":"15.9","Brain RNA - spinal cord [nTPM]":"14.5","Brain RNA - thalamus [nTPM]":"23.7","Brain RNA - white matter [nTPM]":"17.4","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"33.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"21.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - dendritic cells [nTPM]":"28.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.8","Single Cell Type RNA - Early spermatids [nTPM]":"21.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"6.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"3.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"16.4","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"18.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"67.5","Single Cell Type RNA - Muller glia cells [nTPM]":"15.0","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.5","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"48.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.8","Single Cell Type RNA - Spermatocytes [nTPM]":"34.1","Single Cell Type RNA - Spermatogonia [nTPM]":"21.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"4.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.8","Single Cell Type RNA - Urothelial cells [nTPM]":"12.3"},{"Gene":"S1PR2","Gene synonym":["AGR16","DFNB68","EDG5","Gpcr13","H218"],"Ensembl":"ENSG00000267534","Gene description":"Sphingosine-1-phosphate receptor 2","Uniprot":["O95136"],"Chromosome":"19","Position":"10221433-10231331","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"92.9","Early spermatids":"92.3","Late spermatids":"184.9","Syncytiotrophoblasts":"68.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"45.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"45.0","T-cells":"12.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"29.4","Daudi":"54.1","U-266\/70":"38.9","U-698":"57.3","WM-115":"38.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014255","HPA014307"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear speckles","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA014255":null,"HPA014307":"AB_1847989"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.36e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.7","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"6.4","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"10.4","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"4.8","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"3.3","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"3.1","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"18.5","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"4.1","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"10.9","Tissue RNA - urinary bladder [nTPM]":"8.3","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"3.0","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"6.9","Cell RNA - ASC diff [nTPM]":"18.2","Cell RNA - ASC TERT1 [nTPM]":"22.2","Cell RNA - BEWO [nTPM]":"29.4","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"1.9","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"54.1","Cell RNA - EFO-21 [nTPM]":"5.1","Cell RNA - fHDF\/TERT166 [nTPM]":"8.2","Cell RNA - GAMG [nTPM]":"2.3","Cell RNA - HaCaT [nTPM]":"1.7","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"2.7","Cell RNA - HEL [nTPM]":"1.2","Cell RNA - HeLa [nTPM]":"1.2","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"6.1","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"12.2","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.8","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"5.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"2.6","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"11.1","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"2.5","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"3.8","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"2.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"2.5","Cell RNA - SK-BR-3 [nTPM]":"1.5","Cell RNA - SK-MEL-30 [nTPM]":"3.8","Cell RNA - SuSa [nTPM]":"2.6","Cell RNA - T-47d [nTPM]":"1.2","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"6.9","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"15.9","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"38.9","Cell RNA - U-266\/84 [nTPM]":"19.6","Cell RNA - U-698 [nTPM]":"57.3","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"2.7","Cell RNA - WM-115 [nTPM]":"38.6","Blood RNA - basophil [nTPM]":"45.0","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"7.2","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"8.9","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"9.2","Blood RNA - memory CD8 T-cell [nTPM]":"7.0","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"12.4","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"2.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"92.9","Single Cell Type RNA - dendritic cells [nTPM]":"5.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.6","Single Cell Type RNA - Early spermatids [nTPM]":"92.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.1","Single Cell Type RNA - Fibroblasts [nTPM]":"17.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"184.9","Single Cell Type RNA - Leydig cells [nTPM]":"22.1","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"68.4","Single Cell Type RNA - T-cells [nTPM]":"4.2","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"SACS","Gene synonym":["ARSACS","DKFZp686B15167","DNAJC29","KIAA0730","PPP1R138","SPAX6"],"Ensembl":"ENSG00000151835","Gene description":"Sacsin molecular chaperone","Uniprot":["Q9NZJ4"],"Chromosome":"13","Position":"23328826-23433740","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"70.5","Excitatory neurons":"86.3","Inhibitory neurons":"108.2","Oligodendrocyte precursor cells":"76.4","Oligodendrocytes":"111.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017714"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB017714":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-4"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"4.4","Tissue RNA - amygdala [nTPM]":"4.7","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"10.0","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"4.3","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"16.1","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"8.0","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"6.2","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"3.7","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"8.7","Tissue RNA - hippocampal formation [nTPM]":"7.6","Tissue RNA - hypothalamus [nTPM]":"3.0","Tissue RNA - kidney [nTPM]":"3.2","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"4.8","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"8.4","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"4.7","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"15.2","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"7.6","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"6.6","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"14.0","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"5.0","Tissue RNA - smooth muscle [nTPM]":"4.9","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"8.5","Tissue RNA - stomach 1 [nTPM]":"5.1","Tissue RNA - testis [nTPM]":"6.8","Tissue RNA - thalamus [nTPM]":"10.3","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"13.1","Tissue RNA - tonsil [nTPM]":"3.6","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"11.4","Cell RNA - A-431 [nTPM]":"8.1","Cell RNA - A549 [nTPM]":"10.5","Cell RNA - AF22 [nTPM]":"21.3","Cell RNA - AN3-CA [nTPM]":"6.5","Cell RNA - ASC diff [nTPM]":"6.5","Cell RNA - ASC TERT1 [nTPM]":"24.3","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"18.1","Cell RNA - BJ hTERT+ [nTPM]":"23.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"5.0","Cell RNA - CAPAN-2 [nTPM]":"4.2","Cell RNA - Daudi [nTPM]":"5.5","Cell RNA - EFO-21 [nTPM]":"7.4","Cell RNA - fHDF\/TERT166 [nTPM]":"38.8","Cell RNA - GAMG [nTPM]":"9.0","Cell RNA - HaCaT [nTPM]":"1.6","Cell RNA - HAP1 [nTPM]":"30.7","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"22.5","Cell RNA - HDLM-2 [nTPM]":"12.9","Cell RNA - HEK 293 [nTPM]":"12.6","Cell RNA - HEL [nTPM]":"20.7","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"7.4","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"38.1","Cell RNA - HMC-1 [nTPM]":"7.9","Cell RNA - HSkMC [nTPM]":"7.8","Cell RNA - hTCEpi [nTPM]":"2.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.3","Cell RNA - hTERT-HME1 [nTPM]":"21.2","Cell RNA - hTERT-RPE1 [nTPM]":"9.7","Cell RNA - HUVEC TERT2 [nTPM]":"23.1","Cell RNA - JURKAT [nTPM]":"17.0","Cell RNA - K-562 [nTPM]":"12.1","Cell RNA - Karpas-707 [nTPM]":"2.6","Cell RNA - LHCN-M2 [nTPM]":"31.6","Cell RNA - MCF7 [nTPM]":"3.8","Cell RNA - MOLT-4 [nTPM]":"13.6","Cell RNA - NB-4 [nTPM]":"14.6","Cell RNA - NTERA-2 [nTPM]":"17.5","Cell RNA - OE19 [nTPM]":"2.8","Cell RNA - PC-3 [nTPM]":"8.2","Cell RNA - REH [nTPM]":"16.0","Cell RNA - RH-30 [nTPM]":"38.7","Cell RNA - RPMI-8226 [nTPM]":"16.7","Cell RNA - RPTEC TERT1 [nTPM]":"12.0","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"15.4","Cell RNA - SH-SY5Y [nTPM]":"14.8","Cell RNA - SiHa [nTPM]":"10.0","Cell RNA - SK-BR-3 [nTPM]":"3.6","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"9.7","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"10.0","Cell RNA - TIME [nTPM]":"49.8","Cell RNA - U-138 MG [nTPM]":"21.1","Cell RNA - U-2 OS [nTPM]":"17.4","Cell RNA - U-2197 [nTPM]":"11.5","Cell RNA - U-251 MG [nTPM]":"34.6","Cell RNA - U-266\/70 [nTPM]":"5.0","Cell RNA - U-266\/84 [nTPM]":"5.7","Cell RNA - U-698 [nTPM]":"13.3","Cell RNA - U-87 MG [nTPM]":"10.1","Cell RNA - U-937 [nTPM]":"13.2","Cell RNA - WM-115 [nTPM]":"18.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"4.7","Brain RNA - basal ganglia [nTPM]":"10.0","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"16.1","Brain RNA - hippocampal formation [nTPM]":"7.6","Brain RNA - hypothalamus [nTPM]":"3.0","Brain RNA - medulla oblongata [nTPM]":"8.4","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"10.3","Brain RNA - white matter [nTPM]":"11.4","Single Cell Type RNA - Adipocytes [nTPM]":"10.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"70.5","Single Cell Type RNA - B-cells [nTPM]":"14.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"16.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"15.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.0","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.1","Single Cell Type RNA - Endothelial cells [nTPM]":"11.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"86.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"17.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.3","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"18.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"108.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.9","Single Cell Type RNA - Langerhans cells [nTPM]":"19.4","Single Cell Type RNA - Late spermatids [nTPM]":"11.6","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"8.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"13.6","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"76.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"111.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.9","Single Cell Type RNA - Spermatocytes [nTPM]":"20.5","Single Cell Type RNA - Spermatogonia [nTPM]":"9.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"18.1","Single Cell Type RNA - Theca cells [nTPM]":"20.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"SAG","Gene synonym":["ARRESTIN","RP47"],"Ensembl":"ENSG00000130561","Gene description":"S-antigen visual arrestin","Uniprot":["P10523"],"Chromosome":"2","Position":"233307816-233347055","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital stationary night blindness","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"474","RNA tissue specific nTPM":{"retina":"1466.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"6946.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004946"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004946":"AB_2667304"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-5"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1466.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"651.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"869.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"40.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"41.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"338.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.5","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"121.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1191.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6946.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"SAMD12","Gene synonym":["FLJ39458"],"Ensembl":"ENSG00000177570","Gene description":"Sterile alpha motif domain containing 12","Uniprot":["Q8N8I0"],"Chromosome":"8","Position":"118189455-118622112","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"537.6","Inhibitory neurons":"531.7","Oligodendrocytes":"1158.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"34.6","U-266\/70":"14.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024634"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA024634":"AB_1856549"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.52e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"4.9","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"8.8","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"4.1","Tissue RNA - fallopian tube [nTPM]":"5.3","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"6.9","Tissue RNA - hippocampal formation [nTPM]":"7.5","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"3.7","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"2.0","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"5.7","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"4.4","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"8.4","Cell RNA - A-431 [nTPM]":"10.2","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.1","Cell RNA - BJ [nTPM]":"3.4","Cell RNA - BJ hTERT+ [nTPM]":"10.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.3","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"12.1","Cell RNA - Daudi [nTPM]":"3.4","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"8.2","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"2.0","Cell RNA - HBEC3-KT [nTPM]":"4.7","Cell RNA - HBF TERT88 [nTPM]":"11.9","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"5.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"2.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.6","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"2.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"5.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"6.0","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"2.0","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"13.2","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"9.7","Cell RNA - RPTEC TERT1 [nTPM]":"5.4","Cell RNA - RT4 [nTPM]":"13.5","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.8","Cell RNA - SK-BR-3 [nTPM]":"34.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.1","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"14.9","Cell RNA - U-266\/84 [nTPM]":"10.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"1.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"4.9","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"8.8","Brain RNA - hippocampal formation [nTPM]":"7.5","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"8.4","Single Cell Type RNA - Adipocytes [nTPM]":"4.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"112.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"95.0","Single Cell Type RNA - Astrocytes [nTPM]":"53.5","Single Cell Type RNA - B-cells [nTPM]":"8.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"16.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"57.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"12.9","Single Cell Type RNA - Early spermatids [nTPM]":"5.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"13.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.3","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"537.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.4","Single Cell Type RNA - granulocytes [nTPM]":"56.8","Single Cell Type RNA - Granulosa cells [nTPM]":"4.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"5.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"531.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"163.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"4.5","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"122.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1158.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"16.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"68.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"8.9","Single Cell Type RNA - Theca cells [nTPM]":"4.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.9","Single Cell Type RNA - Urothelial cells [nTPM]":"13.6"},{"Gene":"SBF1","Gene synonym":["DENND7A","MTMR5"],"Ensembl":"ENSG00000100241","Gene description":"SET binding factor 1","Uniprot":["O95248"],"Chromosome":"22","Position":"50445000-50475035","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074004"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA074004":"AB_2732249"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.46e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.8","Tissue RNA - adrenal gland [nTPM]":"32.3","Tissue RNA - amygdala [nTPM]":"50.8","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"57.3","Tissue RNA - bone marrow [nTPM]":"20.6","Tissue RNA - breast [nTPM]":"24.2","Tissue RNA - cerebellum [nTPM]":"31.8","Tissue RNA - cerebral cortex [nTPM]":"72.4","Tissue RNA - cervix [nTPM]":"25.9","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"32.9","Tissue RNA - duodenum [nTPM]":"14.8","Tissue RNA - endometrium 1 [nTPM]":"29.5","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"43.9","Tissue RNA - fallopian tube [nTPM]":"27.2","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"38.7","Tissue RNA - hippocampal formation [nTPM]":"70.1","Tissue RNA - hypothalamus [nTPM]":"28.5","Tissue RNA - kidney [nTPM]":"30.5","Tissue RNA - liver [nTPM]":"23.4","Tissue RNA - lung [nTPM]":"26.8","Tissue RNA - lymph node [nTPM]":"28.8","Tissue RNA - medulla oblongata [nTPM]":"52.0","Tissue RNA - midbrain [nTPM]":"39.2","Tissue RNA - ovary [nTPM]":"30.4","Tissue RNA - pancreas [nTPM]":"48.0","Tissue RNA - parathyroid gland [nTPM]":"7.1","Tissue RNA - pituitary gland [nTPM]":"28.6","Tissue RNA - placenta [nTPM]":"8.8","Tissue RNA - pons [nTPM]":"46.5","Tissue RNA - prostate [nTPM]":"28.5","Tissue RNA - rectum [nTPM]":"4.9","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"26.9","Tissue RNA - seminal vesicle [nTPM]":"11.6","Tissue RNA - skeletal muscle [nTPM]":"75.7","Tissue RNA - skin 1 [nTPM]":"42.2","Tissue RNA - small intestine [nTPM]":"38.6","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"32.8","Tissue RNA - spleen [nTPM]":"35.4","Tissue RNA - stomach 1 [nTPM]":"30.1","Tissue RNA - testis [nTPM]":"111.2","Tissue RNA - thalamus [nTPM]":"44.1","Tissue RNA - thymus [nTPM]":"32.7","Tissue RNA - thyroid gland [nTPM]":"62.3","Tissue RNA - tongue [nTPM]":"14.4","Tissue RNA - tonsil [nTPM]":"14.7","Tissue RNA - urinary bladder [nTPM]":"28.3","Tissue RNA - vagina [nTPM]":"27.3","Tissue RNA - white matter [nTPM]":"63.5","Cell RNA - A-431 [nTPM]":"34.3","Cell RNA - A549 [nTPM]":"28.2","Cell RNA - AF22 [nTPM]":"24.0","Cell RNA - AN3-CA [nTPM]":"32.9","Cell RNA - ASC diff [nTPM]":"24.3","Cell RNA - ASC TERT1 [nTPM]":"18.6","Cell RNA - BEWO [nTPM]":"65.9","Cell RNA - BJ [nTPM]":"23.5","Cell RNA - BJ hTERT+ [nTPM]":"20.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.7","Cell RNA - CACO-2 [nTPM]":"39.0","Cell RNA - CAPAN-2 [nTPM]":"23.7","Cell RNA - Daudi [nTPM]":"78.1","Cell RNA - EFO-21 [nTPM]":"16.7","Cell RNA - fHDF\/TERT166 [nTPM]":"27.9","Cell RNA - GAMG [nTPM]":"23.9","Cell RNA - HaCaT [nTPM]":"31.4","Cell RNA - HAP1 [nTPM]":"19.9","Cell RNA - HBEC3-KT [nTPM]":"28.7","Cell RNA - HBF TERT88 [nTPM]":"5.3","Cell RNA - HDLM-2 [nTPM]":"28.6","Cell RNA - HEK 293 [nTPM]":"76.0","Cell RNA - HEL [nTPM]":"17.6","Cell RNA - HeLa [nTPM]":"59.6","Cell RNA - Hep G2 [nTPM]":"50.7","Cell RNA - HHSteC [nTPM]":"41.7","Cell RNA - HL-60 [nTPM]":"54.7","Cell RNA - HMC-1 [nTPM]":"26.1","Cell RNA - HSkMC [nTPM]":"25.0","Cell RNA - hTCEpi [nTPM]":"44.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.1","Cell RNA - hTERT-HME1 [nTPM]":"21.0","Cell RNA - hTERT-RPE1 [nTPM]":"17.0","Cell RNA - HUVEC TERT2 [nTPM]":"14.8","Cell RNA - JURKAT [nTPM]":"41.6","Cell RNA - K-562 [nTPM]":"28.8","Cell RNA - Karpas-707 [nTPM]":"20.8","Cell RNA - LHCN-M2 [nTPM]":"15.0","Cell RNA - MCF7 [nTPM]":"42.6","Cell RNA - MOLT-4 [nTPM]":"54.8","Cell RNA - NB-4 [nTPM]":"52.4","Cell RNA - NTERA-2 [nTPM]":"10.1","Cell RNA - OE19 [nTPM]":"26.1","Cell RNA - PC-3 [nTPM]":"31.7","Cell RNA - REH [nTPM]":"71.0","Cell RNA - RH-30 [nTPM]":"45.6","Cell RNA - RPMI-8226 [nTPM]":"48.3","Cell RNA - RPTEC TERT1 [nTPM]":"12.8","Cell RNA - RT4 [nTPM]":"27.3","Cell RNA - SCLC-21H [nTPM]":"19.1","Cell RNA - SH-SY5Y [nTPM]":"46.0","Cell RNA - SiHa [nTPM]":"36.5","Cell RNA - SK-BR-3 [nTPM]":"35.5","Cell RNA - SK-MEL-30 [nTPM]":"47.7","Cell RNA - SuSa [nTPM]":"10.5","Cell RNA - T-47d [nTPM]":"20.7","Cell RNA - THP-1 [nTPM]":"25.2","Cell RNA - TIME [nTPM]":"25.1","Cell RNA - U-138 MG [nTPM]":"33.9","Cell RNA - U-2 OS [nTPM]":"49.6","Cell RNA - U-2197 [nTPM]":"24.3","Cell RNA - U-251 MG [nTPM]":"29.7","Cell RNA - U-266\/70 [nTPM]":"38.1","Cell RNA - U-266\/84 [nTPM]":"13.4","Cell RNA - U-698 [nTPM]":"37.6","Cell RNA - U-87 MG [nTPM]":"38.8","Cell RNA - U-937 [nTPM]":"22.1","Cell RNA - WM-115 [nTPM]":"32.7","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"5.6","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"50.8","Brain RNA - basal ganglia [nTPM]":"57.3","Brain RNA - cerebellum [nTPM]":"31.8","Brain RNA - cerebral cortex [nTPM]":"72.4","Brain RNA - hippocampal formation [nTPM]":"70.1","Brain RNA - hypothalamus [nTPM]":"28.5","Brain RNA - medulla oblongata [nTPM]":"52.0","Brain RNA - midbrain [nTPM]":"39.2","Brain RNA - pons [nTPM]":"46.5","Brain RNA - spinal cord [nTPM]":"32.8","Brain RNA - thalamus [nTPM]":"44.1","Brain RNA - white matter [nTPM]":"63.5","Single Cell Type RNA - Adipocytes [nTPM]":"5.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.8","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"13.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"15.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"9.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - dendritic cells [nTPM]":"21.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.2","Single Cell Type RNA - Early spermatids [nTPM]":"32.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.9","Single Cell Type RNA - Fibroblasts [nTPM]":"10.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"9.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.9","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.9","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"21.4","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"9.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"10.8","Single Cell Type RNA - Muller glia cells [nTPM]":"6.9","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.9","Single Cell Type RNA - Paneth cells [nTPM]":"8.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"15.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.6","Single Cell Type RNA - Spermatocytes [nTPM]":"25.5","Single Cell Type RNA - Spermatogonia [nTPM]":"23.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"12.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.3","Single Cell Type RNA - Urothelial cells [nTPM]":"10.1"},{"Gene":"SBF2","Gene synonym":["CMT4B2","DENND7B","KIAA1766","MTMR13"],"Ensembl":"ENSG00000133812","Gene description":"SET binding factor 2","Uniprot":["Q86WG5"],"Chromosome":"11","Position":"9778667-10294219","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Charcot-Marie-Tooth disease","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"224.6","Excitatory neurons":"244.9","Inhibitory neurons":"367.4","Microglial cells":"273.6","Oligodendrocyte precursor cells":"290.5","Oligodendrocytes":"228.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"105.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050933"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Intermediate filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Intermediate filaments","Cytosol"],"Antibody RRID":{"HPA050933":"AB_2681280"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.66e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.3","Tissue RNA - adrenal gland [nTPM]":"7.6","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"9.2","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"9.2","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"15.2","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"9.3","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"11.3","Tissue RNA - epididymis [nTPM]":"9.1","Tissue RNA - esophagus [nTPM]":"11.6","Tissue RNA - fallopian tube [nTPM]":"10.2","Tissue RNA - gallbladder [nTPM]":"10.4","Tissue RNA - heart muscle [nTPM]":"8.9","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"7.7","Tissue RNA - kidney [nTPM]":"13.8","Tissue RNA - liver [nTPM]":"9.5","Tissue RNA - lung [nTPM]":"7.4","Tissue RNA - lymph node [nTPM]":"3.9","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"8.1","Tissue RNA - ovary [nTPM]":"18.0","Tissue RNA - pancreas [nTPM]":"5.1","Tissue RNA - parathyroid gland [nTPM]":"17.1","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"14.2","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"10.6","Tissue RNA - rectum [nTPM]":"10.5","Tissue RNA - retina [nTPM]":"14.9","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"10.9","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"7.8","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"10.8","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"6.1","Tissue RNA - thyroid gland [nTPM]":"16.7","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"11.2","Tissue RNA - vagina [nTPM]":"8.2","Tissue RNA - white matter [nTPM]":"8.2","Cell RNA - A-431 [nTPM]":"15.1","Cell RNA - A549 [nTPM]":"12.1","Cell RNA - AF22 [nTPM]":"20.8","Cell RNA - AN3-CA [nTPM]":"15.0","Cell RNA - ASC diff [nTPM]":"27.1","Cell RNA - ASC TERT1 [nTPM]":"35.4","Cell RNA - BEWO [nTPM]":"105.4","Cell RNA - BJ [nTPM]":"11.6","Cell RNA - BJ hTERT+ [nTPM]":"20.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.2","Cell RNA - CACO-2 [nTPM]":"9.1","Cell RNA - CAPAN-2 [nTPM]":"18.1","Cell RNA - Daudi [nTPM]":"5.8","Cell RNA - EFO-21 [nTPM]":"6.2","Cell RNA - fHDF\/TERT166 [nTPM]":"20.6","Cell RNA - GAMG [nTPM]":"19.1","Cell RNA - HaCaT [nTPM]":"9.8","Cell RNA - HAP1 [nTPM]":"12.5","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"22.9","Cell RNA - HDLM-2 [nTPM]":"6.2","Cell RNA - HEK 293 [nTPM]":"8.6","Cell RNA - HEL [nTPM]":"2.5","Cell RNA - HeLa [nTPM]":"9.1","Cell RNA - Hep G2 [nTPM]":"11.9","Cell RNA - HHSteC [nTPM]":"10.6","Cell RNA - HL-60 [nTPM]":"5.6","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"17.5","Cell RNA - hTCEpi [nTPM]":"12.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.6","Cell RNA - hTERT-HME1 [nTPM]":"25.8","Cell RNA - hTERT-RPE1 [nTPM]":"20.2","Cell RNA - HUVEC TERT2 [nTPM]":"21.8","Cell RNA - JURKAT [nTPM]":"12.1","Cell RNA - K-562 [nTPM]":"5.1","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"15.8","Cell RNA - MCF7 [nTPM]":"4.3","Cell RNA - MOLT-4 [nTPM]":"8.1","Cell RNA - NB-4 [nTPM]":"1.5","Cell RNA - NTERA-2 [nTPM]":"9.1","Cell RNA - OE19 [nTPM]":"13.5","Cell RNA - PC-3 [nTPM]":"13.3","Cell RNA - REH [nTPM]":"7.5","Cell RNA - RH-30 [nTPM]":"14.5","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"11.9","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"6.9","Cell RNA - SH-SY5Y [nTPM]":"15.4","Cell RNA - SiHa [nTPM]":"15.7","Cell RNA - SK-BR-3 [nTPM]":"22.4","Cell RNA - SK-MEL-30 [nTPM]":"10.0","Cell RNA - SuSa [nTPM]":"10.6","Cell RNA - T-47d [nTPM]":"6.7","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"24.4","Cell RNA - U-138 MG [nTPM]":"23.1","Cell RNA - U-2 OS [nTPM]":"11.5","Cell RNA - U-2197 [nTPM]":"24.3","Cell RNA - U-251 MG [nTPM]":"9.5","Cell RNA - U-266\/70 [nTPM]":"1.7","Cell RNA - U-266\/84 [nTPM]":"4.6","Cell RNA - U-698 [nTPM]":"8.0","Cell RNA - U-87 MG [nTPM]":"17.4","Cell RNA - U-937 [nTPM]":"2.7","Cell RNA - WM-115 [nTPM]":"17.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"9.2","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"7.7","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"8.1","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"8.2","Single Cell Type RNA - Adipocytes [nTPM]":"50.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"83.9","Single Cell Type RNA - Astrocytes [nTPM]":"224.6","Single Cell Type RNA - B-cells [nTPM]":"16.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"35.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"30.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"75.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - dendritic cells [nTPM]":"14.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.9","Single Cell Type RNA - Early spermatids [nTPM]":"18.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.1","Single Cell Type RNA - Endothelial cells [nTPM]":"40.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.8","Single Cell Type RNA - Erythroid cells [nTPM]":"11.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"244.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.9","Single Cell Type RNA - Fibroblasts [nTPM]":"40.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.1","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"41.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"16.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.6","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"367.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.2","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"55.0","Single Cell Type RNA - Langerhans cells [nTPM]":"34.1","Single Cell Type RNA - Late spermatids [nTPM]":"9.2","Single Cell Type RNA - Leydig cells [nTPM]":"51.0","Single Cell Type RNA - Macrophages [nTPM]":"44.8","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"273.6","Single Cell Type RNA - monocytes [nTPM]":"37.6","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"290.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"228.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.5","Single Cell Type RNA - Paneth cells [nTPM]":"21.2","Single Cell Type RNA - Peritubular cells [nTPM]":"27.1","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"56.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"71.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.8","Single Cell Type RNA - Spermatocytes [nTPM]":"24.5","Single Cell Type RNA - Spermatogonia [nTPM]":"17.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - T-cells [nTPM]":"20.6","Single Cell Type RNA - Theca cells [nTPM]":"25.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.1","Single Cell Type RNA - Urothelial cells [nTPM]":"47.4"},{"Gene":"SCARB2","Gene synonym":["CD36L2","HLGP85","LIMP-2","LIMPII","SR-BII"],"Ensembl":"ENSG00000138760","Gene description":"Scavenger receptor class B member 2","Uniprot":["Q14108"],"Chromosome":"4","Position":"76158737-76234536","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"12.5","classical monocyte":"14.1","intermediate monocyte":"26.0","myeloid DC":"8.2","non-classical monocyte":"24.9","plasmacytoid DC":"28.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"28.9","granulocytes":"12.5","monocytes":"26.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"499.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015415","HPA018014"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9200","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB015415":"AB_831511","HPA018014":"AB_1852881"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.82e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"60.6","Tissue RNA - adrenal gland [nTPM]":"24.0","Tissue RNA - amygdala [nTPM]":"33.5","Tissue RNA - appendix [nTPM]":"27.7","Tissue RNA - basal ganglia [nTPM]":"63.5","Tissue RNA - bone marrow [nTPM]":"7.3","Tissue RNA - breast [nTPM]":"56.7","Tissue RNA - cerebellum [nTPM]":"58.9","Tissue RNA - cerebral cortex [nTPM]":"38.9","Tissue RNA - cervix [nTPM]":"60.8","Tissue RNA - choroid plexus [nTPM]":"18.9","Tissue RNA - colon [nTPM]":"61.6","Tissue RNA - duodenum [nTPM]":"39.2","Tissue RNA - endometrium 1 [nTPM]":"44.1","Tissue RNA - epididymis [nTPM]":"58.4","Tissue RNA - esophagus [nTPM]":"33.9","Tissue RNA - fallopian tube [nTPM]":"45.4","Tissue RNA - gallbladder [nTPM]":"60.0","Tissue RNA - heart muscle [nTPM]":"61.6","Tissue RNA - hippocampal formation [nTPM]":"29.6","Tissue RNA - hypothalamus [nTPM]":"48.6","Tissue RNA - kidney [nTPM]":"46.8","Tissue RNA - liver [nTPM]":"89.9","Tissue RNA - lung [nTPM]":"77.1","Tissue RNA - lymph node [nTPM]":"20.2","Tissue RNA - medulla oblongata [nTPM]":"62.2","Tissue RNA - midbrain [nTPM]":"49.6","Tissue RNA - ovary [nTPM]":"58.9","Tissue RNA - pancreas [nTPM]":"58.9","Tissue RNA - parathyroid gland [nTPM]":"63.6","Tissue RNA - pituitary gland [nTPM]":"11.1","Tissue RNA - placenta [nTPM]":"80.2","Tissue RNA - pons [nTPM]":"62.5","Tissue RNA - prostate [nTPM]":"72.3","Tissue RNA - rectum [nTPM]":"64.0","Tissue RNA - retina [nTPM]":"53.2","Tissue RNA - salivary gland [nTPM]":"80.5","Tissue RNA - seminal vesicle [nTPM]":"55.4","Tissue RNA - skeletal muscle [nTPM]":"89.8","Tissue RNA - skin 1 [nTPM]":"26.0","Tissue RNA - small intestine [nTPM]":"49.1","Tissue RNA - smooth muscle [nTPM]":"57.8","Tissue RNA - spinal cord [nTPM]":"60.1","Tissue RNA - spleen [nTPM]":"47.0","Tissue RNA - stomach 1 [nTPM]":"60.7","Tissue RNA - testis [nTPM]":"19.4","Tissue RNA - thalamus [nTPM]":"50.7","Tissue RNA - thymus [nTPM]":"21.3","Tissue RNA - thyroid gland [nTPM]":"65.9","Tissue RNA - tongue [nTPM]":"81.3","Tissue RNA - tonsil [nTPM]":"20.6","Tissue RNA - urinary bladder [nTPM]":"65.3","Tissue RNA - vagina [nTPM]":"25.1","Tissue RNA - white matter [nTPM]":"92.9","Cell RNA - A-431 [nTPM]":"39.8","Cell RNA - A549 [nTPM]":"38.4","Cell RNA - AF22 [nTPM]":"48.9","Cell RNA - AN3-CA [nTPM]":"97.1","Cell RNA - ASC diff [nTPM]":"499.7","Cell RNA - ASC TERT1 [nTPM]":"242.0","Cell RNA - BEWO [nTPM]":"35.8","Cell RNA - BJ [nTPM]":"131.5","Cell RNA - BJ hTERT+ [nTPM]":"250.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"114.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"178.2","Cell RNA - CACO-2 [nTPM]":"72.5","Cell RNA - CAPAN-2 [nTPM]":"112.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"85.1","Cell RNA - fHDF\/TERT166 [nTPM]":"262.3","Cell RNA - GAMG [nTPM]":"109.6","Cell RNA - HaCaT [nTPM]":"28.3","Cell RNA - HAP1 [nTPM]":"28.3","Cell RNA - HBEC3-KT [nTPM]":"78.9","Cell RNA - HBF TERT88 [nTPM]":"96.0","Cell RNA - HDLM-2 [nTPM]":"138.8","Cell RNA - HEK 293 [nTPM]":"30.1","Cell RNA - HEL [nTPM]":"3.2","Cell RNA - HeLa [nTPM]":"32.9","Cell RNA - Hep G2 [nTPM]":"25.3","Cell RNA - HHSteC [nTPM]":"129.9","Cell RNA - HL-60 [nTPM]":"19.0","Cell RNA - HMC-1 [nTPM]":"12.1","Cell RNA - HSkMC [nTPM]":"186.9","Cell RNA - hTCEpi [nTPM]":"72.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"117.3","Cell RNA - hTERT-HME1 [nTPM]":"54.5","Cell RNA - hTERT-RPE1 [nTPM]":"268.9","Cell RNA - HUVEC TERT2 [nTPM]":"200.6","Cell RNA - JURKAT [nTPM]":"10.0","Cell RNA - K-562 [nTPM]":"15.6","Cell RNA - Karpas-707 [nTPM]":"188.6","Cell RNA - LHCN-M2 [nTPM]":"159.2","Cell RNA - MCF7 [nTPM]":"58.2","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"4.0","Cell RNA - NTERA-2 [nTPM]":"9.7","Cell RNA - OE19 [nTPM]":"120.3","Cell RNA - PC-3 [nTPM]":"23.6","Cell RNA - REH [nTPM]":"23.3","Cell RNA - RH-30 [nTPM]":"82.7","Cell RNA - RPMI-8226 [nTPM]":"42.0","Cell RNA - RPTEC TERT1 [nTPM]":"64.4","Cell RNA - RT4 [nTPM]":"43.6","Cell RNA - SCLC-21H [nTPM]":"101.3","Cell RNA - SH-SY5Y [nTPM]":"110.2","Cell RNA - SiHa [nTPM]":"104.7","Cell RNA - SK-BR-3 [nTPM]":"61.3","Cell RNA - SK-MEL-30 [nTPM]":"115.5","Cell RNA - SuSa [nTPM]":"49.3","Cell RNA - T-47d [nTPM]":"34.6","Cell RNA - THP-1 [nTPM]":"17.1","Cell RNA - TIME [nTPM]":"131.3","Cell RNA - U-138 MG [nTPM]":"125.9","Cell RNA - U-2 OS [nTPM]":"48.5","Cell RNA - U-2197 [nTPM]":"104.7","Cell RNA - U-251 MG [nTPM]":"47.5","Cell RNA - U-266\/70 [nTPM]":"167.6","Cell RNA - U-266\/84 [nTPM]":"98.8","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"158.1","Cell RNA - U-937 [nTPM]":"22.2","Cell RNA - WM-115 [nTPM]":"170.9","Blood RNA - basophil [nTPM]":"12.5","Blood RNA - classical monocyte [nTPM]":"14.1","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"2.8","Blood RNA - intermediate monocyte [nTPM]":"26.0","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"8.2","Blood RNA - naive B-cell [nTPM]":"3.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"24.9","Blood RNA - plasmacytoid DC [nTPM]":"28.9","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"6.1","Brain RNA - amygdala [nTPM]":"33.5","Brain RNA - basal ganglia [nTPM]":"63.5","Brain RNA - cerebellum [nTPM]":"58.9","Brain RNA - cerebral cortex [nTPM]":"38.9","Brain RNA - hippocampal formation [nTPM]":"29.6","Brain RNA - hypothalamus [nTPM]":"48.6","Brain RNA - medulla oblongata [nTPM]":"62.2","Brain RNA - midbrain [nTPM]":"49.6","Brain RNA - pons [nTPM]":"62.5","Brain RNA - spinal cord [nTPM]":"60.1","Brain RNA - thalamus [nTPM]":"50.7","Brain RNA - white matter [nTPM]":"92.9","Single Cell Type RNA - Adipocytes [nTPM]":"89.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"176.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"52.4","Single Cell Type RNA - Astrocytes [nTPM]":"47.3","Single Cell Type RNA - B-cells [nTPM]":"20.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"90.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"64.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"109.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"69.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"53.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"87.2","Single Cell Type RNA - Club cells [nTPM]":"52.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"99.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.3","Single Cell Type RNA - dendritic cells [nTPM]":"43.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"109.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"119.9","Single Cell Type RNA - Early spermatids [nTPM]":"7.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"74.0","Single Cell Type RNA - Endothelial cells [nTPM]":"69.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"102.4","Single Cell Type RNA - Erythroid cells [nTPM]":"28.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"57.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"72.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.5","Single Cell Type RNA - Fibroblasts [nTPM]":"108.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"88.8","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"84.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"79.6","Single Cell Type RNA - Hepatocytes [nTPM]":"108.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"143.4","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"77.1","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"165.7","Single Cell Type RNA - Langerhans cells [nTPM]":"27.5","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"45.4","Single Cell Type RNA - Macrophages [nTPM]":"76.2","Single Cell Type RNA - Melanocytes [nTPM]":"67.6","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"43.5","Single Cell Type RNA - Muller glia cells [nTPM]":"87.2","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"106.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"201.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"78.0","Single Cell Type RNA - Paneth cells [nTPM]":"68.3","Single Cell Type RNA - Peritubular cells [nTPM]":"66.5","Single Cell Type RNA - Plasma cells [nTPM]":"82.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"133.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"103.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"54.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"81.7","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"91.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"68.1","Single Cell Type RNA - Spermatocytes [nTPM]":"18.2","Single Cell Type RNA - Spermatogonia [nTPM]":"16.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.4","Single Cell Type RNA - T-cells [nTPM]":"16.3","Single Cell Type RNA - Theca cells [nTPM]":"56.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.3","Single Cell Type RNA - Urothelial cells [nTPM]":"93.4"},{"Gene":"SCN11A","Gene synonym":["NaN","Nav1.9","SCN12A","SNS-2"],"Ensembl":"ENSG00000168356","Gene description":"Sodium voltage-gated channel alpha subunit 11","Uniprot":["Q9UI33"],"Chromosome":"3","Position":"38845764-39052157","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"3.0","placenta":"1.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"5.4","Astrocytes":"7.8","Early spermatids":"7.0","Sertoli cells":"6.6","Spermatocytes":"4.4","Spermatogonia":"6.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"1.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036746","HPA036747"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036746":"AB_10696785","HPA036747":"AB_2675287"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"3.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"7.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"SCN1A","Gene synonym":["FEB3","GEFSP2","HBSCI","NAC1","Nav1.1","SCN1","SMEI"],"Ensembl":"ENSG00000144285","Gene description":"Sodium voltage-gated channel alpha subunit 1","Uniprot":["P35498"],"Chromosome":"2","Position":"165984641-166149214","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Autism","Autism spectrum disorder","Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"24.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Excitatory neurons":"409.9","Inhibitory neurons":"494.6","Oligodendrocyte precursor cells":"692.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"ASC TERT1":"6.1","Hep G2":"3.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078664"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA078664":"AB_2686888"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"4.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"4.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"2.1","Tissue RNA - cerebral cortex [nTPM]":"24.7","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"14.2","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"10.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"6.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.2","Brain RNA - basal ganglia [nTPM]":"4.2","Brain RNA - cerebellum [nTPM]":"2.1","Brain RNA - cerebral cortex [nTPM]":"24.7","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"14.2","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"10.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.9","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"47.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"409.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"494.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"692.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SCN1B","Gene synonym":[],"Ensembl":"ENSG00000105711","Gene description":"Sodium voltage-gated channel beta subunit 1","Uniprot":["Q07699"],"Chromosome":"19","Position":"35030470-35040449","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Atrial fibrillation","Brugada syndrome","Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"256.5","skeletal muscle":"572.0","tongue":"227.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"67.9","Excitatory neurons":"50.4","Hofbauer cells":"31.3","Inhibitory neurons":"48.3","Kupffer cells":"35.1","Macrophages":"29.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"17.5","EFO-21":"12.7","TIME":"26.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"349.1"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.2","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"48.2","Tissue RNA - appendix [nTPM]":"3.3","Tissue RNA - basal ganglia [nTPM]":"53.0","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"16.3","Tissue RNA - cerebellum [nTPM]":"95.8","Tissue RNA - cerebral cortex [nTPM]":"256.5","Tissue RNA - cervix [nTPM]":"15.5","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"9.7","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"9.4","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"21.7","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"95.4","Tissue RNA - hippocampal formation [nTPM]":"45.0","Tissue RNA - hypothalamus [nTPM]":"97.2","Tissue RNA - kidney [nTPM]":"8.3","Tissue RNA - liver [nTPM]":"8.5","Tissue RNA - lung [nTPM]":"11.1","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"120.4","Tissue RNA - midbrain [nTPM]":"67.0","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"12.3","Tissue RNA - parathyroid gland [nTPM]":"18.2","Tissue RNA - pituitary gland [nTPM]":"17.4","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"115.7","Tissue RNA - prostate [nTPM]":"8.7","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"10.7","Tissue RNA - salivary gland [nTPM]":"15.4","Tissue RNA - seminal vesicle [nTPM]":"3.6","Tissue RNA - skeletal muscle [nTPM]":"572.0","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"8.0","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"52.2","Tissue RNA - spleen [nTPM]":"19.8","Tissue RNA - stomach 1 [nTPM]":"8.4","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"153.5","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"11.1","Tissue RNA - tongue [nTPM]":"227.8","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"13.4","Tissue RNA - vagina [nTPM]":"10.5","Tissue RNA - white matter [nTPM]":"113.6","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"17.5","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"5.2","Cell RNA - ASC TERT1 [nTPM]":"7.8","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"7.1","Cell RNA - BJ hTERT+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.9","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"7.1","Cell RNA - GAMG [nTPM]":"3.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"4.5","Cell RNA - HHSteC [nTPM]":"6.9","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"2.5","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"6.8","Cell RNA - HUVEC TERT2 [nTPM]":"11.6","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"2.2","Cell RNA - MCF7 [nTPM]":"1.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"5.1","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"1.8","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"8.1","Cell RNA - SH-SY5Y [nTPM]":"4.3","Cell RNA - SiHa [nTPM]":"0.9","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"26.1","Cell RNA - U-138 MG [nTPM]":"6.7","Cell RNA - U-2 OS [nTPM]":"6.6","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"4.6","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"4.8","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"48.2","Brain RNA - basal ganglia [nTPM]":"53.0","Brain RNA - cerebellum [nTPM]":"95.8","Brain RNA - cerebral cortex [nTPM]":"256.5","Brain RNA - hippocampal formation [nTPM]":"45.0","Brain RNA - hypothalamus [nTPM]":"97.2","Brain RNA - medulla oblongata [nTPM]":"120.4","Brain RNA - midbrain [nTPM]":"67.0","Brain RNA - pons [nTPM]":"115.7","Brain RNA - spinal cord [nTPM]":"52.2","Brain RNA - thalamus [nTPM]":"153.5","Brain RNA - white matter [nTPM]":"113.6","Single Cell Type RNA - Adipocytes [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.3","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"67.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"2.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"9.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.3","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"35.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"29.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"3.0","Single Cell Type RNA - Muller glia cells [nTPM]":"13.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"SCN2A","Gene synonym":["HBSCI","HBSCII","Nav1.2","SCN2A1","SCN2A2"],"Ensembl":"ENSG00000136531","Gene description":"Sodium voltage-gated channel alpha subunit 2","Uniprot":["Q99250"],"Chromosome":"2","Position":"165194993-165392310","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"26.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"440.4","Inhibitory neurons":"364.7","Oligodendrocyte precursor cells":"246.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HSkMC":"2.1","U-138 MG":"3.4","U-266\/84":"8.1","U-87 MG":"2.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022567"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022567":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"15.8","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"17.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"26.1","Tissue RNA - cerebral cortex [nTPM]":"20.1","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"22.2","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"3.4","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"8.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"15.8","Brain RNA - basal ganglia [nTPM]":"17.5","Brain RNA - cerebellum [nTPM]":"26.1","Brain RNA - cerebral cortex [nTPM]":"20.1","Brain RNA - hippocampal formation [nTPM]":"22.2","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"18.3","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"49.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"440.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"364.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"60.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"246.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SCN3A","Gene synonym":["Nav1.3"],"Ensembl":"ENSG00000153253","Gene description":"Sodium voltage-gated channel alpha subunit 3","Uniprot":["Q9NY46"],"Chromosome":"2","Position":"165087526-165204050","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"16.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"78.4","Excitatory neurons":"227.3","Inhibitory neurons":"169.4","Oligodendrocyte precursor cells":"358.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"30","RNA blood cell specific nTPM":{"memory B-cell":"13.2","naive B-cell":"15.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"B-cells":"15.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"JURKAT":"5.9","Karpas-707":"10.3","MOLT-4":"30.3","RPTEC TERT1":"14.9","SH-SY5Y":"6.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035396"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035396":"AB_2674607"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"10.9","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"16.9","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"8.8","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"9.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"13.4","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"5.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"10.3","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"30.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"1.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"14.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.8","Cell RNA - SH-SY5Y [nTPM]":"6.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"2.2","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"13.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"15.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"10.9","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"16.9","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"8.8","Brain RNA - pons [nTPM]":"9.2","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"13.4","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"6.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"78.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"227.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"169.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"11.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"358.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"5.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SCN4A","Gene synonym":["HYKPP","HYPP","Nav1.4","SkM1"],"Ensembl":"ENSG00000007314","Gene description":"Sodium voltage-gated channel alpha subunit 4","Uniprot":["P35499"],"Chromosome":"17","Position":"63938554-63972918","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"137.4","tongue":"54.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"46.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"2.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"REH":"15.0","RH-30":"45.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053992"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA053992":"AB_2797249"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.9","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"16.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"137.4","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"4.3","Tissue RNA - tongue [nTPM]":"54.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"2.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"15.0","Cell RNA - RH-30 [nTPM]":"45.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"2.8","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"1.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"46.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SCN8A","Gene synonym":["CerIII","CIAT","MED","NaCh6","Nav1.6","PN4"],"Ensembl":"ENSG00000196876","Gene description":"Sodium voltage-gated channel alpha subunit 8","Uniprot":["Q9UQD0"],"Chromosome":"12","Position":"51590266-51812864","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"35.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Excitatory neurons":"336.7","Inhibitory neurons":"280.1","Oligodendrocyte precursor cells":"104.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"35.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"13.7","ASC TERT1":"13.5","WM-115":"13.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022169","HPA043937","HPA073590"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cell Junctions"],"Antibody RRID":{"CAB022169":null,"HPA043937":null,"HPA073590":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"8.9","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"35.0","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"11.4","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"6.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"7.9","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"1.7","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"13.7","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"1.8","Cell RNA - ASC TERT1 [nTPM]":"13.5","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"8.0","Cell RNA - BJ hTERT+ [nTPM]":"12.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.5","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"1.6","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"1.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.9","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"2.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"10.5","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.5","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"9.8","Cell RNA - JURKAT [nTPM]":"3.5","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"5.5","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"4.9","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"4.8","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"5.6","Cell RNA - SH-SY5Y [nTPM]":"2.2","Cell RNA - SiHa [nTPM]":"4.5","Cell RNA - SK-BR-3 [nTPM]":"2.1","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"2.1","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"2.8","Cell RNA - U-138 MG [nTPM]":"8.9","Cell RNA - U-2 OS [nTPM]":"6.3","Cell RNA - U-2197 [nTPM]":"3.3","Cell RNA - U-251 MG [nTPM]":"5.2","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.8","Cell RNA - U-937 [nTPM]":"1.9","Cell RNA - WM-115 [nTPM]":"13.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"8.9","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"35.0","Brain RNA - hippocampal formation [nTPM]":"11.4","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"16.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"336.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"4.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"280.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"104.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"SCN9A","Gene synonym":["ETHA","Nav1.7","NE-NA","NENA","PN1"],"Ensembl":"ENSG00000169432","Gene description":"Sodium voltage-gated channel alpha subunit 9","Uniprot":["Q15858"],"Chromosome":"2","Position":"166195185-166376001","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"21.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"43.2","Hofbauer cells":"67.5","Inhibitory neurons":"48.2","Langerhans cells":"42.8","Oligodendrocyte precursor cells":"133.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"plasmacytoid DC":"23.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"dendritic cells":"23.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"23.0","BJ hTERT+":"16.8","HHSteC":"19.0","hTERT-RPE1":"15.6"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"hypothalamus":"9.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013679","HPA061843"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Plasma membrane","Actin filaments","Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"CAB013679":null,"HPA061843":"AB_2684625"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.30e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.7","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"5.3","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"4.2","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"3.4","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.2","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"21.9","Tissue RNA - kidney [nTPM]":"1.7","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"8.2","Tissue RNA - midbrain [nTPM]":"19.4","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"3.1","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"18.2","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.5","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"9.6","Cell RNA - ASC TERT1 [nTPM]":"7.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"23.0","Cell RNA - BJ hTERT+ [nTPM]":"16.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2.8","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"6.5","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"1.7","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"1.9","Cell RNA - HHSteC [nTPM]":"19.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.1","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"15.6","Cell RNA - HUVEC TERT2 [nTPM]":"1.1","Cell RNA - JURKAT [nTPM]":"1.2","Cell RNA - K-562 [nTPM]":"6.1","Cell RNA - Karpas-707 [nTPM]":"6.6","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"3.6","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"3.3","Cell RNA - RPMI-8226 [nTPM]":"9.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.4","Cell RNA - RT4 [nTPM]":"9.5","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"9.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"23.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.3","Brain RNA - basal ganglia [nTPM]":"4.2","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"3.4","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"21.9","Brain RNA - medulla oblongata [nTPM]":"8.2","Brain RNA - midbrain [nTPM]":"19.4","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"18.2","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"4.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"43.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"23.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"5.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"18.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"9.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"67.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.3","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"42.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"11.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"133.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.7","Single Cell Type RNA - Paneth cells [nTPM]":"7.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"4.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"SCO2","Gene synonym":["MYP6","SCO1L"],"Ensembl":"ENSG00000284194","Gene description":"Synthesis of cytochrome C oxidase 2","Uniprot":["O43819"],"Chromosome":"22","Position":"50523568-50526461","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Cardiomyopathy","Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"112.2","Paneth cells":"131.5","Proximal enterocytes":"110.7","Suprabasal keratinocytes":"98.9"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046943","HPA056254"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA046943":"AB_2732536","HPA056254":"AB_2683080"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"16.8","Tissue RNA - adrenal gland [nTPM]":"10.3","Tissue RNA - amygdala [nTPM]":"14.0","Tissue RNA - appendix [nTPM]":"13.4","Tissue RNA - basal ganglia [nTPM]":"13.8","Tissue RNA - bone marrow [nTPM]":"36.5","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"14.4","Tissue RNA - cerebral cortex [nTPM]":"16.8","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"18.2","Tissue RNA - colon [nTPM]":"22.0","Tissue RNA - duodenum [nTPM]":"25.6","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"15.8","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"10.3","Tissue RNA - hippocampal formation [nTPM]":"14.3","Tissue RNA - hypothalamus [nTPM]":"14.4","Tissue RNA - kidney [nTPM]":"8.1","Tissue RNA - liver [nTPM]":"18.4","Tissue RNA - lung [nTPM]":"14.4","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"18.8","Tissue RNA - midbrain [nTPM]":"19.1","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"11.5","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"17.5","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"10.5","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"6.7","Tissue RNA - skeletal muscle [nTPM]":"10.2","Tissue RNA - skin 1 [nTPM]":"11.0","Tissue RNA - small intestine [nTPM]":"19.7","Tissue RNA - smooth muscle [nTPM]":"12.7","Tissue RNA - spinal cord [nTPM]":"16.4","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"10.2","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"17.4","Tissue RNA - thymus [nTPM]":"11.2","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"10.1","Tissue RNA - tonsil [nTPM]":"10.3","Tissue RNA - urinary bladder [nTPM]":"13.0","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"17.4","Cell RNA - A-431 [nTPM]":"37.4","Cell RNA - A549 [nTPM]":"29.9","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"12.5","Cell RNA - ASC diff [nTPM]":"17.7","Cell RNA - ASC TERT1 [nTPM]":"24.2","Cell RNA - BEWO [nTPM]":"18.7","Cell RNA - BJ [nTPM]":"19.5","Cell RNA - BJ hTERT+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.8","Cell RNA - CACO-2 [nTPM]":"35.3","Cell RNA - CAPAN-2 [nTPM]":"17.8","Cell RNA - Daudi [nTPM]":"42.7","Cell RNA - EFO-21 [nTPM]":"19.7","Cell RNA - fHDF\/TERT166 [nTPM]":"22.6","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"36.0","Cell RNA - HAP1 [nTPM]":"19.3","Cell RNA - HBEC3-KT [nTPM]":"31.5","Cell RNA - HBF TERT88 [nTPM]":"6.1","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"82.5","Cell RNA - HEL [nTPM]":"13.8","Cell RNA - HeLa [nTPM]":"20.2","Cell RNA - Hep G2 [nTPM]":"46.7","Cell RNA - HHSteC [nTPM]":"44.6","Cell RNA - HL-60 [nTPM]":"43.8","Cell RNA - HMC-1 [nTPM]":"18.3","Cell RNA - HSkMC [nTPM]":"38.4","Cell RNA - hTCEpi [nTPM]":"48.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.4","Cell RNA - hTERT-HME1 [nTPM]":"15.8","Cell RNA - hTERT-RPE1 [nTPM]":"10.6","Cell RNA - HUVEC TERT2 [nTPM]":"24.4","Cell RNA - JURKAT [nTPM]":"5.8","Cell RNA - K-562 [nTPM]":"15.6","Cell RNA - Karpas-707 [nTPM]":"32.9","Cell RNA - LHCN-M2 [nTPM]":"16.8","Cell RNA - MCF7 [nTPM]":"55.7","Cell RNA - MOLT-4 [nTPM]":"13.3","Cell RNA - NB-4 [nTPM]":"76.5","Cell RNA - NTERA-2 [nTPM]":"11.0","Cell RNA - OE19 [nTPM]":"15.5","Cell RNA - PC-3 [nTPM]":"54.8","Cell RNA - REH [nTPM]":"26.1","Cell RNA - RH-30 [nTPM]":"7.5","Cell RNA - RPMI-8226 [nTPM]":"65.0","Cell RNA - RPTEC TERT1 [nTPM]":"29.6","Cell RNA - RT4 [nTPM]":"21.3","Cell RNA - SCLC-21H [nTPM]":"16.6","Cell RNA - SH-SY5Y [nTPM]":"23.7","Cell RNA - SiHa [nTPM]":"24.4","Cell RNA - SK-BR-3 [nTPM]":"70.7","Cell RNA - SK-MEL-30 [nTPM]":"63.5","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"26.1","Cell RNA - THP-1 [nTPM]":"24.7","Cell RNA - TIME [nTPM]":"25.8","Cell RNA - U-138 MG [nTPM]":"16.3","Cell RNA - U-2 OS [nTPM]":"22.6","Cell RNA - U-2197 [nTPM]":"30.2","Cell RNA - U-251 MG [nTPM]":"22.2","Cell RNA - U-266\/70 [nTPM]":"26.1","Cell RNA - U-266\/84 [nTPM]":"15.6","Cell RNA - U-698 [nTPM]":"29.2","Cell RNA - U-87 MG [nTPM]":"35.7","Cell RNA - U-937 [nTPM]":"28.7","Cell RNA - WM-115 [nTPM]":"14.5","Blood RNA - basophil [nTPM]":"19.1","Blood RNA - classical monocyte [nTPM]":"21.8","Blood RNA - eosinophil [nTPM]":"12.2","Blood RNA - gdT-cell [nTPM]":"43.9","Blood RNA - intermediate monocyte [nTPM]":"19.9","Blood RNA - MAIT T-cell [nTPM]":"42.2","Blood RNA - memory B-cell [nTPM]":"40.1","Blood RNA - memory CD4 T-cell [nTPM]":"38.9","Blood RNA - memory CD8 T-cell [nTPM]":"44.1","Blood RNA - myeloid DC [nTPM]":"34.9","Blood RNA - naive B-cell [nTPM]":"33.4","Blood RNA - naive CD4 T-cell [nTPM]":"29.2","Blood RNA - naive CD8 T-cell [nTPM]":"32.6","Blood RNA - neutrophil [nTPM]":"21.6","Blood RNA - NK-cell [nTPM]":"27.7","Blood RNA - non-classical monocyte [nTPM]":"21.1","Blood RNA - plasmacytoid DC [nTPM]":"56.2","Blood RNA - T-reg [nTPM]":"37.0","Blood RNA - total PBMC [nTPM]":"37.7","Brain RNA - amygdala [nTPM]":"14.0","Brain RNA - basal ganglia [nTPM]":"13.8","Brain RNA - cerebellum [nTPM]":"14.4","Brain RNA - cerebral cortex [nTPM]":"16.8","Brain RNA - hippocampal formation [nTPM]":"14.3","Brain RNA - hypothalamus [nTPM]":"14.4","Brain RNA - medulla oblongata [nTPM]":"18.8","Brain RNA - midbrain [nTPM]":"19.1","Brain RNA - pons [nTPM]":"17.5","Brain RNA - spinal cord [nTPM]":"16.4","Brain RNA - thalamus [nTPM]":"17.4","Brain RNA - white matter [nTPM]":"17.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"20.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"85.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"7.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"31.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"112.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"15.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"13.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.8","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"14.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"15.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"53.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"63.2","Single Cell Type RNA - Ionocytes [nTPM]":"48.8","Single Cell Type RNA - Kupffer cells [nTPM]":"28.2","Single Cell Type RNA - Langerhans cells [nTPM]":"63.6","Single Cell Type RNA - Late spermatids [nTPM]":"25.6","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"29.2","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"47.3","Single Cell Type RNA - Muller glia cells [nTPM]":"5.5","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"131.5","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"32.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"110.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.5","Single Cell Type RNA - Spermatocytes [nTPM]":"17.3","Single Cell Type RNA - Spermatogonia [nTPM]":"35.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"56.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"98.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"90.7","Single Cell Type RNA - Urothelial cells [nTPM]":"22.3"},{"Gene":"SCP2","Gene synonym":[],"Ensembl":"ENSG00000116171","Gene description":"Sterol carrier protein 2","Uniprot":["P22307"],"Chromosome":"1","Position":"52927276-53051698","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1116.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"1240.7","Proximal enterocytes":"769.0","Proximal tubular cells":"881.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027101","HPA027135","HPA027317"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"640000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Peroxisomes"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA027101":"AB_1856634","HPA027135":"AB_1856633","HPA027317":"AB_10610422"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.05e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.85e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"203.7","Tissue RNA - adrenal gland [nTPM]":"125.5","Tissue RNA - amygdala [nTPM]":"68.5","Tissue RNA - appendix [nTPM]":"92.7","Tissue RNA - basal ganglia [nTPM]":"71.6","Tissue RNA - bone marrow [nTPM]":"111.2","Tissue RNA - breast [nTPM]":"196.6","Tissue RNA - cerebellum [nTPM]":"74.2","Tissue RNA - cerebral cortex [nTPM]":"90.1","Tissue RNA - cervix [nTPM]":"153.8","Tissue RNA - choroid plexus [nTPM]":"79.2","Tissue RNA - colon [nTPM]":"256.7","Tissue RNA - duodenum [nTPM]":"336.3","Tissue RNA - endometrium 1 [nTPM]":"94.6","Tissue RNA - epididymis [nTPM]":"165.5","Tissue RNA - esophagus [nTPM]":"140.2","Tissue RNA - fallopian tube [nTPM]":"119.7","Tissue RNA - gallbladder [nTPM]":"144.6","Tissue RNA - heart muscle [nTPM]":"162.4","Tissue RNA - hippocampal formation [nTPM]":"65.8","Tissue RNA - hypothalamus [nTPM]":"76.1","Tissue RNA - kidney [nTPM]":"319.8","Tissue RNA - liver [nTPM]":"1116.8","Tissue RNA - lung [nTPM]":"140.6","Tissue RNA - lymph node [nTPM]":"106.0","Tissue RNA - medulla oblongata [nTPM]":"75.4","Tissue RNA - midbrain [nTPM]":"72.3","Tissue RNA - ovary [nTPM]":"94.5","Tissue RNA - pancreas [nTPM]":"119.2","Tissue RNA - parathyroid gland [nTPM]":"130.9","Tissue RNA - pituitary gland [nTPM]":"64.7","Tissue RNA - placenta [nTPM]":"79.0","Tissue RNA - pons [nTPM]":"77.9","Tissue RNA - prostate [nTPM]":"150.9","Tissue RNA - rectum [nTPM]":"270.5","Tissue RNA - retina [nTPM]":"76.6","Tissue RNA - salivary gland [nTPM]":"114.0","Tissue RNA - seminal vesicle [nTPM]":"97.3","Tissue RNA - skeletal muscle [nTPM]":"142.0","Tissue RNA - skin 1 [nTPM]":"130.6","Tissue RNA - small intestine [nTPM]":"305.7","Tissue RNA - smooth muscle [nTPM]":"112.9","Tissue RNA - spinal cord [nTPM]":"75.6","Tissue RNA - spleen [nTPM]":"83.9","Tissue RNA - stomach 1 [nTPM]":"234.4","Tissue RNA - testis [nTPM]":"63.4","Tissue RNA - thalamus [nTPM]":"74.7","Tissue RNA - thymus [nTPM]":"131.9","Tissue RNA - thyroid gland [nTPM]":"140.9","Tissue RNA - tongue [nTPM]":"152.8","Tissue RNA - tonsil [nTPM]":"125.5","Tissue RNA - urinary bladder [nTPM]":"139.2","Tissue RNA - vagina [nTPM]":"76.9","Tissue RNA - white matter [nTPM]":"78.9","Cell RNA - A-431 [nTPM]":"120.6","Cell RNA - A549 [nTPM]":"64.8","Cell RNA - AF22 [nTPM]":"85.5","Cell RNA - AN3-CA [nTPM]":"157.9","Cell RNA - ASC diff [nTPM]":"273.6","Cell RNA - ASC TERT1 [nTPM]":"232.6","Cell RNA - BEWO [nTPM]":"92.7","Cell RNA - BJ [nTPM]":"140.0","Cell RNA - BJ hTERT+ [nTPM]":"208.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"90.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"129.2","Cell RNA - CACO-2 [nTPM]":"58.7","Cell RNA - CAPAN-2 [nTPM]":"127.5","Cell RNA - Daudi [nTPM]":"114.7","Cell RNA - EFO-21 [nTPM]":"147.6","Cell RNA - fHDF\/TERT166 [nTPM]":"206.6","Cell RNA - GAMG [nTPM]":"105.3","Cell RNA - HaCaT [nTPM]":"82.5","Cell RNA - HAP1 [nTPM]":"59.6","Cell RNA - HBEC3-KT [nTPM]":"131.0","Cell RNA - HBF TERT88 [nTPM]":"136.5","Cell RNA - HDLM-2 [nTPM]":"168.2","Cell RNA - HEK 293 [nTPM]":"86.4","Cell RNA - HEL [nTPM]":"123.4","Cell RNA - HeLa [nTPM]":"88.8","Cell RNA - Hep G2 [nTPM]":"122.1","Cell RNA - HHSteC [nTPM]":"182.0","Cell RNA - HL-60 [nTPM]":"179.9","Cell RNA - HMC-1 [nTPM]":"197.5","Cell RNA - HSkMC [nTPM]":"190.2","Cell RNA - hTCEpi [nTPM]":"175.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"107.1","Cell RNA - hTERT-HME1 [nTPM]":"52.9","Cell RNA - hTERT-RPE1 [nTPM]":"196.2","Cell RNA - HUVEC TERT2 [nTPM]":"260.0","Cell RNA - JURKAT [nTPM]":"132.6","Cell RNA - K-562 [nTPM]":"111.5","Cell RNA - Karpas-707 [nTPM]":"58.2","Cell RNA - LHCN-M2 [nTPM]":"184.7","Cell RNA - MCF7 [nTPM]":"70.1","Cell RNA - MOLT-4 [nTPM]":"200.7","Cell RNA - NB-4 [nTPM]":"155.2","Cell RNA - NTERA-2 [nTPM]":"94.6","Cell RNA - OE19 [nTPM]":"304.4","Cell RNA - PC-3 [nTPM]":"126.0","Cell RNA - REH [nTPM]":"101.9","Cell RNA - RH-30 [nTPM]":"150.9","Cell RNA - RPMI-8226 [nTPM]":"158.3","Cell RNA - RPTEC TERT1 [nTPM]":"252.2","Cell RNA - RT4 [nTPM]":"192.2","Cell RNA - SCLC-21H [nTPM]":"70.9","Cell RNA - SH-SY5Y [nTPM]":"85.3","Cell RNA - SiHa [nTPM]":"122.0","Cell RNA - SK-BR-3 [nTPM]":"246.3","Cell RNA - SK-MEL-30 [nTPM]":"121.6","Cell RNA - SuSa [nTPM]":"189.6","Cell RNA - T-47d [nTPM]":"125.9","Cell RNA - THP-1 [nTPM]":"201.4","Cell RNA - TIME [nTPM]":"203.8","Cell RNA - U-138 MG [nTPM]":"122.4","Cell RNA - U-2 OS [nTPM]":"63.4","Cell RNA - U-2197 [nTPM]":"213.2","Cell RNA - U-251 MG [nTPM]":"114.9","Cell RNA - U-266\/70 [nTPM]":"95.9","Cell RNA - U-266\/84 [nTPM]":"131.0","Cell RNA - U-698 [nTPM]":"134.2","Cell RNA - U-87 MG [nTPM]":"159.0","Cell RNA - U-937 [nTPM]":"175.7","Cell RNA - WM-115 [nTPM]":"113.8","Blood RNA - basophil [nTPM]":"285.6","Blood RNA - classical monocyte [nTPM]":"193.7","Blood RNA - eosinophil [nTPM]":"286.0","Blood RNA - gdT-cell [nTPM]":"185.9","Blood RNA - intermediate monocyte [nTPM]":"208.8","Blood RNA - MAIT T-cell [nTPM]":"152.1","Blood RNA - memory B-cell [nTPM]":"150.8","Blood RNA - memory CD4 T-cell [nTPM]":"144.9","Blood RNA - memory CD8 T-cell [nTPM]":"184.6","Blood RNA - myeloid DC [nTPM]":"230.5","Blood RNA - naive B-cell [nTPM]":"132.6","Blood RNA - naive CD4 T-cell [nTPM]":"120.8","Blood RNA - naive CD8 T-cell [nTPM]":"171.4","Blood RNA - neutrophil [nTPM]":"29.4","Blood RNA - NK-cell [nTPM]":"176.8","Blood RNA - non-classical monocyte [nTPM]":"204.2","Blood RNA - plasmacytoid DC [nTPM]":"150.9","Blood RNA - T-reg [nTPM]":"195.2","Blood RNA - total PBMC [nTPM]":"289.5","Brain RNA - amygdala [nTPM]":"68.5","Brain RNA - basal ganglia [nTPM]":"71.6","Brain RNA - cerebellum [nTPM]":"74.2","Brain RNA - cerebral cortex [nTPM]":"90.1","Brain RNA - hippocampal formation [nTPM]":"65.8","Brain RNA - hypothalamus [nTPM]":"76.1","Brain RNA - medulla oblongata [nTPM]":"75.4","Brain RNA - midbrain [nTPM]":"72.3","Brain RNA - pons [nTPM]":"77.9","Brain RNA - spinal cord [nTPM]":"75.6","Brain RNA - thalamus [nTPM]":"74.7","Brain RNA - white matter [nTPM]":"78.9","Single Cell Type RNA - Adipocytes [nTPM]":"167.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"134.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"198.4","Single Cell Type RNA - Astrocytes [nTPM]":"52.2","Single Cell Type RNA - B-cells [nTPM]":"91.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"150.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"123.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"222.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"110.4","Single Cell Type RNA - Bipolar cells [nTPM]":"37.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"189.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"86.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"157.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"258.7","Single Cell Type RNA - Club cells [nTPM]":"166.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"185.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"182.7","Single Cell Type RNA - dendritic cells [nTPM]":"128.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"512.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"473.5","Single Cell Type RNA - Ductal cells [nTPM]":"168.1","Single Cell Type RNA - Early spermatids [nTPM]":"57.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"150.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"81.6","Single Cell Type RNA - Endothelial cells [nTPM]":"126.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"235.1","Single Cell Type RNA - Erythroid cells [nTPM]":"93.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"162.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"156.5","Single Cell Type RNA - Fibroblasts [nTPM]":"124.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"180.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"125.3","Single Cell Type RNA - granulocytes [nTPM]":"138.4","Single Cell Type RNA - Granulosa cells [nTPM]":"54.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"146.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1240.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"203.5","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"462.7","Single Cell Type RNA - Ionocytes [nTPM]":"250.3","Single Cell Type RNA - Kupffer cells [nTPM]":"230.1","Single Cell Type RNA - Langerhans cells [nTPM]":"173.1","Single Cell Type RNA - Late spermatids [nTPM]":"51.4","Single Cell Type RNA - Leydig cells [nTPM]":"184.2","Single Cell Type RNA - Macrophages [nTPM]":"148.8","Single Cell Type RNA - Melanocytes [nTPM]":"192.1","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"154.6","Single Cell Type RNA - Muller glia cells [nTPM]":"132.0","Single Cell Type RNA - NK-cells [nTPM]":"181.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"157.4","Single Cell Type RNA - Paneth cells [nTPM]":"503.4","Single Cell Type RNA - Peritubular cells [nTPM]":"171.9","Single Cell Type RNA - Plasma cells [nTPM]":"76.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"118.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"769.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"881.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"178.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.1","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"72.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"110.6","Single Cell Type RNA - Spermatocytes [nTPM]":"20.4","Single Cell Type RNA - Spermatogonia [nTPM]":"19.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"150.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"170.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"133.9","Single Cell Type RNA - T-cells [nTPM]":"132.9","Single Cell Type RNA - Theca cells [nTPM]":"110.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"336.4","Single Cell Type RNA - Urothelial cells [nTPM]":"187.8"},{"Gene":"SCYL1","Gene synonym":["GKLP","HT019","MGC78454","NKTL","NTKL","P105","TAPK","TEIF","TRAP"],"Ensembl":"ENSG00000142186","Gene description":"SCY1 like pseudokinase 1","Uniprot":["Q96KG9"],"Chromosome":"11","Position":"65525077-65538704","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["ER-Golgi transport","Transcription","Transcription regulation","Transport"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Mental retardation","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"138.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015015"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015015":"AB_1856643"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Tissue RNA - adipose tissue [nTPM]":"43.4","Tissue RNA - adrenal gland [nTPM]":"69.3","Tissue RNA - amygdala [nTPM]":"36.6","Tissue RNA - appendix [nTPM]":"26.4","Tissue RNA - basal ganglia [nTPM]":"37.4","Tissue RNA - bone marrow [nTPM]":"32.8","Tissue RNA - breast [nTPM]":"41.1","Tissue RNA - cerebellum [nTPM]":"33.1","Tissue RNA - cerebral cortex [nTPM]":"53.9","Tissue RNA - cervix [nTPM]":"46.8","Tissue RNA - choroid plexus [nTPM]":"37.1","Tissue RNA - colon [nTPM]":"46.7","Tissue RNA - duodenum [nTPM]":"28.0","Tissue RNA - endometrium 1 [nTPM]":"49.4","Tissue RNA - epididymis [nTPM]":"32.5","Tissue RNA - esophagus [nTPM]":"40.0","Tissue RNA - fallopian tube [nTPM]":"44.0","Tissue RNA - gallbladder [nTPM]":"26.3","Tissue RNA - heart muscle [nTPM]":"59.7","Tissue RNA - hippocampal formation [nTPM]":"39.2","Tissue RNA - hypothalamus [nTPM]":"34.1","Tissue RNA - kidney [nTPM]":"45.7","Tissue RNA - liver [nTPM]":"83.2","Tissue RNA - lung [nTPM]":"42.4","Tissue RNA - lymph node [nTPM]":"30.7","Tissue RNA - medulla oblongata [nTPM]":"36.0","Tissue RNA - midbrain [nTPM]":"35.2","Tissue RNA - ovary [nTPM]":"52.4","Tissue RNA - pancreas [nTPM]":"61.6","Tissue RNA - parathyroid gland [nTPM]":"35.5","Tissue RNA - pituitary gland [nTPM]":"44.7","Tissue RNA - placenta [nTPM]":"34.6","Tissue RNA - pons [nTPM]":"35.5","Tissue RNA - prostate [nTPM]":"47.3","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"48.5","Tissue RNA - seminal vesicle [nTPM]":"33.7","Tissue RNA - skeletal muscle [nTPM]":"104.5","Tissue RNA - skin 1 [nTPM]":"44.5","Tissue RNA - small intestine [nTPM]":"39.6","Tissue RNA - smooth muscle [nTPM]":"27.5","Tissue RNA - spinal cord [nTPM]":"30.9","Tissue RNA - spleen [nTPM]":"46.4","Tissue RNA - stomach 1 [nTPM]":"50.0","Tissue RNA - testis [nTPM]":"50.6","Tissue RNA - thalamus [nTPM]":"37.7","Tissue RNA - thymus [nTPM]":"23.4","Tissue RNA - thyroid gland [nTPM]":"48.8","Tissue RNA - tongue [nTPM]":"51.6","Tissue RNA - tonsil [nTPM]":"21.8","Tissue RNA - urinary bladder [nTPM]":"47.8","Tissue RNA - vagina [nTPM]":"39.5","Tissue RNA - white matter [nTPM]":"39.0","Cell RNA - A-431 [nTPM]":"55.0","Cell RNA - A549 [nTPM]":"45.9","Cell RNA - AF22 [nTPM]":"36.6","Cell RNA - AN3-CA [nTPM]":"50.9","Cell RNA - ASC diff [nTPM]":"65.4","Cell RNA - ASC TERT1 [nTPM]":"56.6","Cell RNA - BEWO [nTPM]":"50.0","Cell RNA - BJ [nTPM]":"66.6","Cell RNA - BJ hTERT+ [nTPM]":"89.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"77.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"60.4","Cell RNA - CACO-2 [nTPM]":"66.9","Cell RNA - CAPAN-2 [nTPM]":"32.2","Cell RNA - Daudi [nTPM]":"39.2","Cell RNA - EFO-21 [nTPM]":"65.7","Cell RNA - fHDF\/TERT166 [nTPM]":"86.9","Cell RNA - GAMG [nTPM]":"66.2","Cell RNA - HaCaT [nTPM]":"49.1","Cell RNA - HAP1 [nTPM]":"38.7","Cell RNA - HBEC3-KT [nTPM]":"50.1","Cell RNA - HBF TERT88 [nTPM]":"27.0","Cell RNA - HDLM-2 [nTPM]":"46.6","Cell RNA - HEK 293 [nTPM]":"49.7","Cell RNA - HEL [nTPM]":"46.4","Cell RNA - HeLa [nTPM]":"50.8","Cell RNA - Hep G2 [nTPM]":"78.3","Cell RNA - HHSteC [nTPM]":"92.8","Cell RNA - HL-60 [nTPM]":"30.8","Cell RNA - HMC-1 [nTPM]":"64.0","Cell RNA - HSkMC [nTPM]":"79.1","Cell RNA - hTCEpi [nTPM]":"48.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"66.9","Cell RNA - hTERT-HME1 [nTPM]":"49.4","Cell RNA - hTERT-RPE1 [nTPM]":"54.2","Cell RNA - HUVEC TERT2 [nTPM]":"51.6","Cell RNA - JURKAT [nTPM]":"39.7","Cell RNA - K-562 [nTPM]":"49.2","Cell RNA - Karpas-707 [nTPM]":"53.8","Cell RNA - LHCN-M2 [nTPM]":"49.0","Cell RNA - MCF7 [nTPM]":"118.9","Cell RNA - MOLT-4 [nTPM]":"41.4","Cell RNA - NB-4 [nTPM]":"70.4","Cell RNA - NTERA-2 [nTPM]":"35.3","Cell RNA - OE19 [nTPM]":"36.9","Cell RNA - PC-3 [nTPM]":"63.4","Cell RNA - REH [nTPM]":"41.4","Cell RNA - RH-30 [nTPM]":"28.5","Cell RNA - RPMI-8226 [nTPM]":"72.5","Cell RNA - RPTEC TERT1 [nTPM]":"48.1","Cell RNA - RT4 [nTPM]":"48.4","Cell RNA - SCLC-21H [nTPM]":"33.7","Cell RNA - SH-SY5Y [nTPM]":"35.7","Cell RNA - SiHa [nTPM]":"41.2","Cell RNA - SK-BR-3 [nTPM]":"89.6","Cell RNA - SK-MEL-30 [nTPM]":"74.5","Cell RNA - SuSa [nTPM]":"22.4","Cell RNA - T-47d [nTPM]":"88.8","Cell RNA - THP-1 [nTPM]":"38.4","Cell RNA - TIME [nTPM]":"51.4","Cell RNA - U-138 MG [nTPM]":"61.3","Cell RNA - U-2 OS [nTPM]":"41.0","Cell RNA - U-2197 [nTPM]":"100.7","Cell RNA - U-251 MG [nTPM]":"40.1","Cell RNA - U-266\/70 [nTPM]":"73.8","Cell RNA - U-266\/84 [nTPM]":"55.8","Cell RNA - U-698 [nTPM]":"41.4","Cell RNA - U-87 MG [nTPM]":"71.0","Cell RNA - U-937 [nTPM]":"25.3","Cell RNA - WM-115 [nTPM]":"43.7","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"21.1","Blood RNA - eosinophil [nTPM]":"28.4","Blood RNA - gdT-cell [nTPM]":"20.7","Blood RNA - intermediate monocyte [nTPM]":"20.0","Blood RNA - MAIT T-cell [nTPM]":"16.6","Blood RNA - memory B-cell [nTPM]":"14.0","Blood RNA - memory CD4 T-cell [nTPM]":"19.6","Blood RNA - memory CD8 T-cell [nTPM]":"20.9","Blood RNA - myeloid DC [nTPM]":"23.5","Blood RNA - naive B-cell [nTPM]":"14.3","Blood RNA - naive CD4 T-cell [nTPM]":"15.2","Blood RNA - naive CD8 T-cell [nTPM]":"15.0","Blood RNA - neutrophil [nTPM]":"41.9","Blood RNA - NK-cell [nTPM]":"18.2","Blood RNA - non-classical monocyte [nTPM]":"13.6","Blood RNA - plasmacytoid DC [nTPM]":"17.0","Blood RNA - T-reg [nTPM]":"14.4","Blood RNA - total PBMC [nTPM]":"19.8","Brain RNA - amygdala [nTPM]":"36.6","Brain RNA - basal ganglia [nTPM]":"37.4","Brain RNA - cerebellum [nTPM]":"33.1","Brain RNA - cerebral cortex [nTPM]":"53.9","Brain RNA - hippocampal formation [nTPM]":"39.2","Brain RNA - hypothalamus [nTPM]":"34.1","Brain RNA - medulla oblongata [nTPM]":"36.0","Brain RNA - midbrain [nTPM]":"35.2","Brain RNA - pons [nTPM]":"35.5","Brain RNA - spinal cord [nTPM]":"30.9","Brain RNA - thalamus [nTPM]":"37.7","Brain RNA - white matter [nTPM]":"39.0","Single Cell Type RNA - Adipocytes [nTPM]":"22.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.7","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"25.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Bipolar cells [nTPM]":"25.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"26.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"47.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Ductal cells [nTPM]":"37.5","Single Cell Type RNA - Early spermatids [nTPM]":"25.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.7","Single Cell Type RNA - Endothelial cells [nTPM]":"23.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.5","Single Cell Type RNA - Erythroid cells [nTPM]":"22.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"70.0","Single Cell Type RNA - Fibroblasts [nTPM]":"34.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.4","Single Cell Type RNA - granulocytes [nTPM]":"25.4","Single Cell Type RNA - Granulosa cells [nTPM]":"34.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"35.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.9","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"19.2","Single Cell Type RNA - Langerhans cells [nTPM]":"24.3","Single Cell Type RNA - Late spermatids [nTPM]":"25.2","Single Cell Type RNA - Leydig cells [nTPM]":"45.7","Single Cell Type RNA - Macrophages [nTPM]":"24.5","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"34.3","Single Cell Type RNA - Muller glia cells [nTPM]":"26.6","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.4","Single Cell Type RNA - Paneth cells [nTPM]":"31.4","Single Cell Type RNA - Peritubular cells [nTPM]":"45.5","Single Cell Type RNA - Plasma cells [nTPM]":"53.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.8","Single Cell Type RNA - Spermatocytes [nTPM]":"39.5","Single Cell Type RNA - Spermatogonia [nTPM]":"21.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"138.6","Single Cell Type RNA - T-cells [nTPM]":"23.2","Single Cell Type RNA - Theca cells [nTPM]":"44.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.2","Single Cell Type RNA - Urothelial cells [nTPM]":"38.5"},{"Gene":"SELENOI","Gene synonym":["EPT1","KIAA1724","SELI","SEPI"],"Ensembl":"ENSG00000138018","Gene description":"Selenoprotein I","Uniprot":["Q9C0D9"],"Chromosome":"2","Position":"26308547-26395891","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"22.0","Endometrial ciliated cells":"16.3","Glandular and luminal cells":"15.3","Pancreatic endocrine cells":"13.6","Syncytiotrophoblasts":"16.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064125"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064125":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.6","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"7.9","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"12.1","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"11.2","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"8.6","Tissue RNA - duodenum [nTPM]":"12.3","Tissue RNA - endometrium 1 [nTPM]":"4.1","Tissue RNA - epididymis [nTPM]":"5.4","Tissue RNA - esophagus [nTPM]":"11.1","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"10.3","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"23.2","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"3.5","Tissue RNA - pancreas [nTPM]":"9.0","Tissue RNA - parathyroid gland [nTPM]":"17.2","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"6.2","Tissue RNA - rectum [nTPM]":"8.7","Tissue RNA - retina [nTPM]":"9.3","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"18.3","Tissue RNA - small intestine [nTPM]":"18.4","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"4.3","Tissue RNA - stomach 1 [nTPM]":"7.1","Tissue RNA - testis [nTPM]":"4.4","Tissue RNA - thalamus [nTPM]":"7.2","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"7.1","Tissue RNA - tongue [nTPM]":"6.6","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"7.5","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"10.0","Cell RNA - A-431 [nTPM]":"42.7","Cell RNA - A549 [nTPM]":"25.7","Cell RNA - AF22 [nTPM]":"20.9","Cell RNA - AN3-CA [nTPM]":"21.0","Cell RNA - ASC diff [nTPM]":"12.8","Cell RNA - ASC TERT1 [nTPM]":"10.2","Cell RNA - BEWO [nTPM]":"32.0","Cell RNA - BJ [nTPM]":"20.3","Cell RNA - BJ hTERT+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.2","Cell RNA - CACO-2 [nTPM]":"54.5","Cell RNA - CAPAN-2 [nTPM]":"26.6","Cell RNA - Daudi [nTPM]":"49.5","Cell RNA - EFO-21 [nTPM]":"24.2","Cell RNA - fHDF\/TERT166 [nTPM]":"9.5","Cell RNA - GAMG [nTPM]":"21.4","Cell RNA - HaCaT [nTPM]":"34.1","Cell RNA - HAP1 [nTPM]":"32.4","Cell RNA - HBEC3-KT [nTPM]":"17.9","Cell RNA - HBF TERT88 [nTPM]":"14.4","Cell RNA - HDLM-2 [nTPM]":"13.7","Cell RNA - HEK 293 [nTPM]":"15.4","Cell RNA - HEL [nTPM]":"31.3","Cell RNA - HeLa [nTPM]":"17.5","Cell RNA - Hep G2 [nTPM]":"32.3","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"41.9","Cell RNA - HMC-1 [nTPM]":"9.7","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"15.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.3","Cell RNA - hTERT-HME1 [nTPM]":"21.9","Cell RNA - hTERT-RPE1 [nTPM]":"6.1","Cell RNA - HUVEC TERT2 [nTPM]":"9.4","Cell RNA - JURKAT [nTPM]":"17.6","Cell RNA - K-562 [nTPM]":"35.9","Cell RNA - Karpas-707 [nTPM]":"16.6","Cell RNA - LHCN-M2 [nTPM]":"13.5","Cell RNA - MCF7 [nTPM]":"18.4","Cell RNA - MOLT-4 [nTPM]":"25.1","Cell RNA - NB-4 [nTPM]":"20.7","Cell RNA - NTERA-2 [nTPM]":"26.8","Cell RNA - OE19 [nTPM]":"21.6","Cell RNA - PC-3 [nTPM]":"17.4","Cell RNA - REH [nTPM]":"22.6","Cell RNA - RH-30 [nTPM]":"49.2","Cell RNA - RPMI-8226 [nTPM]":"25.0","Cell RNA - RPTEC TERT1 [nTPM]":"19.3","Cell RNA - RT4 [nTPM]":"32.4","Cell RNA - SCLC-21H [nTPM]":"45.7","Cell RNA - SH-SY5Y [nTPM]":"19.4","Cell RNA - SiHa [nTPM]":"17.3","Cell RNA - SK-BR-3 [nTPM]":"36.2","Cell RNA - SK-MEL-30 [nTPM]":"16.4","Cell RNA - SuSa [nTPM]":"17.3","Cell RNA - T-47d [nTPM]":"17.4","Cell RNA - THP-1 [nTPM]":"12.4","Cell RNA - TIME [nTPM]":"15.1","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"22.0","Cell RNA - U-2197 [nTPM]":"22.7","Cell RNA - U-251 MG [nTPM]":"31.7","Cell RNA - U-266\/70 [nTPM]":"22.6","Cell RNA - U-266\/84 [nTPM]":"60.8","Cell RNA - U-698 [nTPM]":"65.8","Cell RNA - U-87 MG [nTPM]":"17.5","Cell RNA - U-937 [nTPM]":"25.4","Cell RNA - WM-115 [nTPM]":"15.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"7.9","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"11.2","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"10.3","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"7.2","Brain RNA - white matter [nTPM]":"10.0","Single Cell Type RNA - Adipocytes [nTPM]":"9.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.1","Single Cell Type RNA - dendritic cells [nTPM]":"11.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.8","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"11.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SEMA4A","Gene synonym":["CORD10","FLJ12287","SEMAB","SemB"],"Ensembl":"ENSG00000196189","Gene description":"Semaphorin 4A","Uniprot":["Q9H3S1"],"Chromosome":"1","Position":"156147366-156177752","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Angiogenesis","Differentiation","Immunity","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Cone-rod dystrophy","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"51.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"63.7","Plasma cells":"61.2","Skeletal myocytes":"100.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"123.9","eosinophil":"120.2","intermediate monocyte":"132.7","myeloid DC":"183.0","neutrophil":"210.7","non-classical monocyte":"76.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"dendritic cells":"183.0","granulocytes":"210.7","monocytes":"132.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"151.8","U-698":"67.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069136"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069136":"AB_2686093"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.1","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"22.7","Tissue RNA - appendix [nTPM]":"24.8","Tissue RNA - basal ganglia [nTPM]":"21.5","Tissue RNA - bone marrow [nTPM]":"37.5","Tissue RNA - breast [nTPM]":"9.1","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"23.2","Tissue RNA - cervix [nTPM]":"10.8","Tissue RNA - choroid plexus [nTPM]":"4.7","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"3.0","Tissue RNA - epididymis [nTPM]":"51.3","Tissue RNA - esophagus [nTPM]":"32.5","Tissue RNA - fallopian tube [nTPM]":"7.9","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"25.3","Tissue RNA - hypothalamus [nTPM]":"23.0","Tissue RNA - kidney [nTPM]":"18.1","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"15.2","Tissue RNA - lymph node [nTPM]":"31.5","Tissue RNA - medulla oblongata [nTPM]":"12.2","Tissue RNA - midbrain [nTPM]":"15.5","Tissue RNA - ovary [nTPM]":"5.2","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"15.3","Tissue RNA - prostate [nTPM]":"16.3","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"19.2","Tissue RNA - seminal vesicle [nTPM]":"12.5","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"32.3","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"3.6","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"26.9","Tissue RNA - stomach 1 [nTPM]":"10.6","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"29.0","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"23.1","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"33.1","Tissue RNA - urinary bladder [nTPM]":"10.8","Tissue RNA - vagina [nTPM]":"17.4","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"12.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"8.1","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"11.7","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"10.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"3.5","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"18.5","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"9.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"2.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"151.8","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"15.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"6.5","Cell RNA - NTERA-2 [nTPM]":"3.6","Cell RNA - OE19 [nTPM]":"12.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"5.4","Cell RNA - RPTEC TERT1 [nTPM]":"17.9","Cell RNA - RT4 [nTPM]":"24.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"19.2","Cell RNA - SK-MEL-30 [nTPM]":"1.0","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"22.3","Cell RNA - THP-1 [nTPM]":"23.3","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"29.3","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"67.6","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"17.5","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"16.0","Blood RNA - classical monocyte [nTPM]":"123.9","Blood RNA - eosinophil [nTPM]":"120.2","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"132.7","Blood RNA - MAIT T-cell [nTPM]":"8.5","Blood RNA - memory B-cell [nTPM]":"13.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"8.0","Blood RNA - myeloid DC [nTPM]":"183.0","Blood RNA - naive B-cell [nTPM]":"10.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"210.7","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"76.1","Blood RNA - plasmacytoid DC [nTPM]":"25.7","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"66.4","Brain RNA - amygdala [nTPM]":"22.7","Brain RNA - basal ganglia [nTPM]":"21.5","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"23.2","Brain RNA - hippocampal formation [nTPM]":"25.3","Brain RNA - hypothalamus [nTPM]":"23.0","Brain RNA - medulla oblongata [nTPM]":"12.2","Brain RNA - midbrain [nTPM]":"15.5","Brain RNA - pons [nTPM]":"15.3","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"29.0","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"13.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"63.7","Single Cell Type RNA - Astrocytes [nTPM]":"25.8","Single Cell Type RNA - B-cells [nTPM]":"13.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"13.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"9.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"20.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.5","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.1","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"22.8","Single Cell Type RNA - Langerhans cells [nTPM]":"42.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"37.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"32.6","Single Cell Type RNA - Muller glia cells [nTPM]":"6.3","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"7.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"61.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"100.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"10.0","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.6","Single Cell Type RNA - Urothelial cells [nTPM]":"15.6"},{"Gene":"SEPTIN9","Gene synonym":["AF17q25","KIAA0991","MSF","MSF1","PNUTL4","SEPT9","SeptD1"],"Ensembl":"ENSG00000184640","Gene description":"Septin 9","Uniprot":["Q9UHD8"],"Chromosome":"17","Position":"77280569-77500596","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"29.9","Cytotrophoblasts":"78.2","dendritic cells":"34.8","Extravillous trophoblasts":"152.8","Hofbauer cells":"67.5","Syncytiotrophoblasts":"70.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042564","HPA050627"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Actin filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"770000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA042564":"AB_2678054","HPA050627":"AB_2681193"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Tissue RNA - adipose tissue [nTPM]":"68.7","Tissue RNA - adrenal gland [nTPM]":"87.9","Tissue RNA - amygdala [nTPM]":"58.8","Tissue RNA - appendix [nTPM]":"148.8","Tissue RNA - basal ganglia [nTPM]":"61.7","Tissue RNA - bone marrow [nTPM]":"89.2","Tissue RNA - breast [nTPM]":"72.8","Tissue RNA - cerebellum [nTPM]":"81.6","Tissue RNA - cerebral cortex [nTPM]":"85.3","Tissue RNA - cervix [nTPM]":"99.3","Tissue RNA - choroid plexus [nTPM]":"59.9","Tissue RNA - colon [nTPM]":"137.8","Tissue RNA - duodenum [nTPM]":"94.9","Tissue RNA - endometrium 1 [nTPM]":"127.5","Tissue RNA - epididymis [nTPM]":"27.0","Tissue RNA - esophagus [nTPM]":"81.9","Tissue RNA - fallopian tube [nTPM]":"89.0","Tissue RNA - gallbladder [nTPM]":"88.3","Tissue RNA - heart muscle [nTPM]":"70.5","Tissue RNA - hippocampal formation [nTPM]":"68.1","Tissue RNA - hypothalamus [nTPM]":"68.6","Tissue RNA - kidney [nTPM]":"75.2","Tissue RNA - liver [nTPM]":"99.5","Tissue RNA - lung [nTPM]":"77.8","Tissue RNA - lymph node [nTPM]":"223.8","Tissue RNA - medulla oblongata [nTPM]":"111.5","Tissue RNA - midbrain [nTPM]":"62.0","Tissue RNA - ovary [nTPM]":"76.4","Tissue RNA - pancreas [nTPM]":"38.7","Tissue RNA - parathyroid gland [nTPM]":"67.2","Tissue RNA - pituitary gland [nTPM]":"63.3","Tissue RNA - placenta [nTPM]":"80.7","Tissue RNA - pons [nTPM]":"76.6","Tissue RNA - prostate [nTPM]":"96.0","Tissue RNA - rectum [nTPM]":"51.9","Tissue RNA - retina [nTPM]":"15.6","Tissue RNA - salivary gland [nTPM]":"76.8","Tissue RNA - seminal vesicle [nTPM]":"75.6","Tissue RNA - skeletal muscle [nTPM]":"73.1","Tissue RNA - skin 1 [nTPM]":"80.3","Tissue RNA - small intestine [nTPM]":"145.1","Tissue RNA - smooth muscle [nTPM]":"84.5","Tissue RNA - spinal cord [nTPM]":"68.2","Tissue RNA - spleen [nTPM]":"152.8","Tissue RNA - stomach 1 [nTPM]":"103.1","Tissue RNA - testis [nTPM]":"60.0","Tissue RNA - thalamus [nTPM]":"65.7","Tissue RNA - thymus [nTPM]":"260.2","Tissue RNA - thyroid gland [nTPM]":"52.9","Tissue RNA - tongue [nTPM]":"43.1","Tissue RNA - tonsil [nTPM]":"151.5","Tissue RNA - urinary bladder [nTPM]":"122.9","Tissue RNA - vagina [nTPM]":"82.4","Tissue RNA - white matter [nTPM]":"71.8","Cell RNA - A-431 [nTPM]":"246.1","Cell RNA - A549 [nTPM]":"342.0","Cell RNA - AF22 [nTPM]":"221.3","Cell RNA - AN3-CA [nTPM]":"186.4","Cell RNA - ASC diff [nTPM]":"257.0","Cell RNA - ASC TERT1 [nTPM]":"417.1","Cell RNA - BEWO [nTPM]":"121.7","Cell RNA - BJ [nTPM]":"188.9","Cell RNA - BJ hTERT+ [nTPM]":"214.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"122.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.0","Cell RNA - CACO-2 [nTPM]":"278.4","Cell RNA - CAPAN-2 [nTPM]":"243.4","Cell RNA - Daudi [nTPM]":"338.7","Cell RNA - EFO-21 [nTPM]":"153.4","Cell RNA - fHDF\/TERT166 [nTPM]":"388.5","Cell RNA - GAMG [nTPM]":"161.2","Cell RNA - HaCaT [nTPM]":"149.1","Cell RNA - HAP1 [nTPM]":"96.6","Cell RNA - HBEC3-KT [nTPM]":"354.8","Cell RNA - HBF TERT88 [nTPM]":"90.4","Cell RNA - HDLM-2 [nTPM]":"6.2","Cell RNA - HEK 293 [nTPM]":"65.0","Cell RNA - HEL [nTPM]":"128.8","Cell RNA - HeLa [nTPM]":"147.3","Cell RNA - Hep G2 [nTPM]":"483.2","Cell RNA - HHSteC [nTPM]":"212.0","Cell RNA - HL-60 [nTPM]":"84.6","Cell RNA - HMC-1 [nTPM]":"218.3","Cell RNA - HSkMC [nTPM]":"215.6","Cell RNA - hTCEpi [nTPM]":"128.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"159.6","Cell RNA - hTERT-HME1 [nTPM]":"136.0","Cell RNA - hTERT-RPE1 [nTPM]":"180.3","Cell RNA - HUVEC TERT2 [nTPM]":"167.5","Cell RNA - JURKAT [nTPM]":"196.4","Cell RNA - K-562 [nTPM]":"144.6","Cell RNA - Karpas-707 [nTPM]":"44.1","Cell RNA - LHCN-M2 [nTPM]":"110.7","Cell RNA - MCF7 [nTPM]":"258.1","Cell RNA - MOLT-4 [nTPM]":"628.1","Cell RNA - NB-4 [nTPM]":"72.0","Cell RNA - NTERA-2 [nTPM]":"207.5","Cell RNA - OE19 [nTPM]":"281.4","Cell RNA - PC-3 [nTPM]":"281.1","Cell RNA - REH [nTPM]":"290.7","Cell RNA - RH-30 [nTPM]":"192.6","Cell RNA - RPMI-8226 [nTPM]":"117.1","Cell RNA - RPTEC TERT1 [nTPM]":"197.5","Cell RNA - RT4 [nTPM]":"337.9","Cell RNA - SCLC-21H [nTPM]":"171.0","Cell RNA - SH-SY5Y [nTPM]":"324.3","Cell RNA - SiHa [nTPM]":"214.2","Cell RNA - SK-BR-3 [nTPM]":"349.6","Cell RNA - SK-MEL-30 [nTPM]":"207.2","Cell RNA - SuSa [nTPM]":"248.6","Cell RNA - T-47d [nTPM]":"260.2","Cell RNA - THP-1 [nTPM]":"60.7","Cell RNA - TIME [nTPM]":"243.6","Cell RNA - U-138 MG [nTPM]":"165.8","Cell RNA - U-2 OS [nTPM]":"147.6","Cell RNA - U-2197 [nTPM]":"197.4","Cell RNA - U-251 MG [nTPM]":"130.2","Cell RNA - U-266\/70 [nTPM]":"10.5","Cell RNA - U-266\/84 [nTPM]":"19.5","Cell RNA - U-698 [nTPM]":"562.6","Cell RNA - U-87 MG [nTPM]":"245.6","Cell RNA - U-937 [nTPM]":"73.7","Cell RNA - WM-115 [nTPM]":"348.7","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"18.4","Blood RNA - eosinophil [nTPM]":"31.1","Blood RNA - gdT-cell [nTPM]":"22.3","Blood RNA - intermediate monocyte [nTPM]":"46.3","Blood RNA - MAIT T-cell [nTPM]":"19.0","Blood RNA - memory B-cell [nTPM]":"16.3","Blood RNA - memory CD4 T-cell [nTPM]":"28.7","Blood RNA - memory CD8 T-cell [nTPM]":"26.4","Blood RNA - myeloid DC [nTPM]":"17.0","Blood RNA - naive B-cell [nTPM]":"17.4","Blood RNA - naive CD4 T-cell [nTPM]":"29.6","Blood RNA - naive CD8 T-cell [nTPM]":"25.8","Blood RNA - neutrophil [nTPM]":"6.1","Blood RNA - NK-cell [nTPM]":"16.9","Blood RNA - non-classical monocyte [nTPM]":"55.3","Blood RNA - plasmacytoid DC [nTPM]":"38.7","Blood RNA - T-reg [nTPM]":"31.8","Blood RNA - total PBMC [nTPM]":"24.9","Brain RNA - amygdala [nTPM]":"58.8","Brain RNA - basal ganglia [nTPM]":"61.7","Brain RNA - cerebellum [nTPM]":"81.6","Brain RNA - cerebral cortex [nTPM]":"85.3","Brain RNA - hippocampal formation [nTPM]":"68.1","Brain RNA - hypothalamus [nTPM]":"68.6","Brain RNA - medulla oblongata [nTPM]":"111.5","Brain RNA - midbrain [nTPM]":"62.0","Brain RNA - pons [nTPM]":"76.6","Brain RNA - spinal cord [nTPM]":"68.2","Brain RNA - thalamus [nTPM]":"65.7","Brain RNA - white matter [nTPM]":"71.8","Single Cell Type RNA - Adipocytes [nTPM]":"29.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"78.2","Single Cell Type RNA - dendritic cells [nTPM]":"34.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"152.8","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"67.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"7.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"70.6","Single Cell Type RNA - T-cells [nTPM]":"6.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SERPINB6","Gene synonym":["CAP","DFNB91","PI6","PTI"],"Ensembl":"ENSG00000124570","Gene description":"Serpin family B member 6","Uniprot":["P35237"],"Chromosome":"6","Position":"2948159-2972165","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"563.0","Late spermatids":"1154.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009668","HPA012736"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4800000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA009668":"AB_1079919","HPA012736":"AB_1856729"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.81e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"122.7","Tissue RNA - adrenal gland [nTPM]":"170.7","Tissue RNA - amygdala [nTPM]":"101.1","Tissue RNA - appendix [nTPM]":"66.9","Tissue RNA - basal ganglia [nTPM]":"108.4","Tissue RNA - bone marrow [nTPM]":"66.6","Tissue RNA - breast [nTPM]":"107.9","Tissue RNA - cerebellum [nTPM]":"103.6","Tissue RNA - cerebral cortex [nTPM]":"134.3","Tissue RNA - cervix [nTPM]":"135.9","Tissue RNA - choroid plexus [nTPM]":"103.8","Tissue RNA - colon [nTPM]":"133.7","Tissue RNA - duodenum [nTPM]":"191.2","Tissue RNA - endometrium 1 [nTPM]":"95.9","Tissue RNA - epididymis [nTPM]":"82.2","Tissue RNA - esophagus [nTPM]":"131.5","Tissue RNA - fallopian tube [nTPM]":"118.9","Tissue RNA - gallbladder [nTPM]":"77.7","Tissue RNA - heart muscle [nTPM]":"243.9","Tissue RNA - hippocampal formation [nTPM]":"98.6","Tissue RNA - hypothalamus [nTPM]":"104.2","Tissue RNA - kidney [nTPM]":"136.7","Tissue RNA - liver [nTPM]":"63.3","Tissue RNA - lung [nTPM]":"151.7","Tissue RNA - lymph node [nTPM]":"52.7","Tissue RNA - medulla oblongata [nTPM]":"111.7","Tissue RNA - midbrain [nTPM]":"107.1","Tissue RNA - ovary [nTPM]":"169.7","Tissue RNA - pancreas [nTPM]":"282.5","Tissue RNA - parathyroid gland [nTPM]":"94.4","Tissue RNA - pituitary gland [nTPM]":"92.0","Tissue RNA - placenta [nTPM]":"133.5","Tissue RNA - pons [nTPM]":"110.6","Tissue RNA - prostate [nTPM]":"160.4","Tissue RNA - rectum [nTPM]":"103.3","Tissue RNA - retina [nTPM]":"56.4","Tissue RNA - salivary gland [nTPM]":"92.5","Tissue RNA - seminal vesicle [nTPM]":"95.6","Tissue RNA - skeletal muscle [nTPM]":"232.0","Tissue RNA - skin 1 [nTPM]":"50.9","Tissue RNA - small intestine [nTPM]":"210.3","Tissue RNA - smooth muscle [nTPM]":"89.4","Tissue RNA - spinal cord [nTPM]":"105.8","Tissue RNA - spleen [nTPM]":"164.5","Tissue RNA - stomach 1 [nTPM]":"115.0","Tissue RNA - testis [nTPM]":"203.8","Tissue RNA - thalamus [nTPM]":"106.7","Tissue RNA - thymus [nTPM]":"26.7","Tissue RNA - thyroid gland [nTPM]":"101.3","Tissue RNA - tongue [nTPM]":"266.8","Tissue RNA - tonsil [nTPM]":"47.2","Tissue RNA - urinary bladder [nTPM]":"107.7","Tissue RNA - vagina [nTPM]":"95.5","Tissue RNA - white matter [nTPM]":"115.4","Cell RNA - A-431 [nTPM]":"156.2","Cell RNA - A549 [nTPM]":"99.6","Cell RNA - AF22 [nTPM]":"32.2","Cell RNA - AN3-CA [nTPM]":"134.3","Cell RNA - ASC diff [nTPM]":"85.6","Cell RNA - ASC TERT1 [nTPM]":"189.2","Cell RNA - BEWO [nTPM]":"99.2","Cell RNA - BJ [nTPM]":"142.1","Cell RNA - BJ hTERT+ [nTPM]":"170.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"109.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"127.3","Cell RNA - CACO-2 [nTPM]":"35.0","Cell RNA - CAPAN-2 [nTPM]":"108.5","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"161.6","Cell RNA - fHDF\/TERT166 [nTPM]":"161.7","Cell RNA - GAMG [nTPM]":"124.8","Cell RNA - HaCaT [nTPM]":"228.8","Cell RNA - HAP1 [nTPM]":"90.3","Cell RNA - HBEC3-KT [nTPM]":"144.1","Cell RNA - HBF TERT88 [nTPM]":"102.2","Cell RNA - HDLM-2 [nTPM]":"204.9","Cell RNA - HEK 293 [nTPM]":"41.2","Cell RNA - HEL [nTPM]":"90.7","Cell RNA - HeLa [nTPM]":"111.8","Cell RNA - Hep G2 [nTPM]":"60.0","Cell RNA - HHSteC [nTPM]":"148.5","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"53.0","Cell RNA - HSkMC [nTPM]":"109.4","Cell RNA - hTCEpi [nTPM]":"98.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"104.8","Cell RNA - hTERT-HME1 [nTPM]":"26.9","Cell RNA - hTERT-RPE1 [nTPM]":"191.1","Cell RNA - HUVEC TERT2 [nTPM]":"263.7","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"118.7","Cell RNA - Karpas-707 [nTPM]":"2.0","Cell RNA - LHCN-M2 [nTPM]":"198.0","Cell RNA - MCF7 [nTPM]":"110.7","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"1.5","Cell RNA - NTERA-2 [nTPM]":"19.1","Cell RNA - OE19 [nTPM]":"175.5","Cell RNA - PC-3 [nTPM]":"188.8","Cell RNA - REH [nTPM]":"10.1","Cell RNA - RH-30 [nTPM]":"59.3","Cell RNA - RPMI-8226 [nTPM]":"130.7","Cell RNA - RPTEC TERT1 [nTPM]":"138.7","Cell RNA - RT4 [nTPM]":"37.1","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"82.5","Cell RNA - SiHa [nTPM]":"116.9","Cell RNA - SK-BR-3 [nTPM]":"17.3","Cell RNA - SK-MEL-30 [nTPM]":"162.4","Cell RNA - SuSa [nTPM]":"118.6","Cell RNA - T-47d [nTPM]":"75.3","Cell RNA - THP-1 [nTPM]":"73.8","Cell RNA - TIME [nTPM]":"188.7","Cell RNA - U-138 MG [nTPM]":"111.1","Cell RNA - U-2 OS [nTPM]":"41.4","Cell RNA - U-2197 [nTPM]":"252.0","Cell RNA - U-251 MG [nTPM]":"97.1","Cell RNA - U-266\/70 [nTPM]":"3.0","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"2.7","Cell RNA - U-87 MG [nTPM]":"85.4","Cell RNA - U-937 [nTPM]":"90.8","Cell RNA - WM-115 [nTPM]":"117.8","Blood RNA - basophil [nTPM]":"60.6","Blood RNA - classical monocyte [nTPM]":"104.9","Blood RNA - eosinophil [nTPM]":"121.2","Blood RNA - gdT-cell [nTPM]":"51.5","Blood RNA - intermediate monocyte [nTPM]":"107.6","Blood RNA - MAIT T-cell [nTPM]":"25.7","Blood RNA - memory B-cell [nTPM]":"27.3","Blood RNA - memory CD4 T-cell [nTPM]":"28.9","Blood RNA - memory CD8 T-cell [nTPM]":"35.5","Blood RNA - myeloid DC [nTPM]":"103.6","Blood RNA - naive B-cell [nTPM]":"22.9","Blood RNA - naive CD4 T-cell [nTPM]":"33.7","Blood RNA - naive CD8 T-cell [nTPM]":"56.1","Blood RNA - neutrophil [nTPM]":"8.6","Blood RNA - NK-cell [nTPM]":"86.0","Blood RNA - non-classical monocyte [nTPM]":"90.7","Blood RNA - plasmacytoid DC [nTPM]":"10.3","Blood RNA - T-reg [nTPM]":"5.0","Blood RNA - total PBMC [nTPM]":"91.1","Brain RNA - amygdala [nTPM]":"101.1","Brain RNA - basal ganglia [nTPM]":"108.4","Brain RNA - cerebellum [nTPM]":"103.6","Brain RNA - cerebral cortex [nTPM]":"134.3","Brain RNA - hippocampal formation [nTPM]":"98.6","Brain RNA - hypothalamus [nTPM]":"104.2","Brain RNA - medulla oblongata [nTPM]":"111.7","Brain RNA - midbrain [nTPM]":"107.1","Brain RNA - pons [nTPM]":"110.6","Brain RNA - spinal cord [nTPM]":"105.8","Brain RNA - thalamus [nTPM]":"106.7","Brain RNA - white matter [nTPM]":"115.4","Single Cell Type RNA - Adipocytes [nTPM]":"127.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"69.6","Single Cell Type RNA - Astrocytes [nTPM]":"34.3","Single Cell Type RNA - B-cells [nTPM]":"33.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"68.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"141.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"28.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"62.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"63.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"142.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"141.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"75.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"146.4","Single Cell Type RNA - dendritic cells [nTPM]":"56.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"237.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"99.7","Single Cell Type RNA - Ductal cells [nTPM]":"194.6","Single Cell Type RNA - Early spermatids [nTPM]":"563.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"89.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"91.4","Single Cell Type RNA - Endothelial cells [nTPM]":"137.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"73.0","Single Cell Type RNA - Erythroid cells [nTPM]":"29.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"338.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"346.6","Single Cell Type RNA - Fibroblasts [nTPM]":"84.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"108.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.8","Single Cell Type RNA - granulocytes [nTPM]":"104.5","Single Cell Type RNA - Granulosa cells [nTPM]":"83.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"232.7","Single Cell Type RNA - Hepatocytes [nTPM]":"31.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"182.3","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"169.7","Single Cell Type RNA - Ionocytes [nTPM]":"114.0","Single Cell Type RNA - Kupffer cells [nTPM]":"181.9","Single Cell Type RNA - Langerhans cells [nTPM]":"70.2","Single Cell Type RNA - Late spermatids [nTPM]":"1154.3","Single Cell Type RNA - Leydig cells [nTPM]":"83.3","Single Cell Type RNA - Macrophages [nTPM]":"124.2","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"92.8","Single Cell Type RNA - monocytes [nTPM]":"151.8","Single Cell Type RNA - Muller glia cells [nTPM]":"172.4","Single Cell Type RNA - NK-cells [nTPM]":"46.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"56.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"318.5","Single Cell Type RNA - Paneth cells [nTPM]":"237.0","Single Cell Type RNA - Peritubular cells [nTPM]":"85.0","Single Cell Type RNA - Plasma cells [nTPM]":"17.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"99.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"418.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"216.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"174.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.4","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"119.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"104.6","Single Cell Type RNA - Spermatocytes [nTPM]":"233.2","Single Cell Type RNA - Spermatogonia [nTPM]":"33.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"161.4","Single Cell Type RNA - T-cells [nTPM]":"42.2","Single Cell Type RNA - Theca cells [nTPM]":"65.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"206.5","Single Cell Type RNA - Urothelial cells [nTPM]":"94.9"},{"Gene":"SERPINI1","Gene synonym":["PI12"],"Ensembl":"ENSG00000163536","Gene description":"Serpin family I member 1","Uniprot":["Q99574"],"Chromosome":"3","Position":"167735243-167825569","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"301.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"219.4","Excitatory neurons":"176.9","Inhibitory neurons":"228.8","Oligodendrocytes":"174.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"29.2","Karpas-707":"29.1","U-266\/84":"28.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001565","HPA056092"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"750000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001565":"AB_1079924","HPA056092":"AB_2683036"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.1","Tissue RNA - adrenal gland [nTPM]":"15.8","Tissue RNA - amygdala [nTPM]":"138.8","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"157.7","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"11.7","Tissue RNA - cerebellum [nTPM]":"115.9","Tissue RNA - cerebral cortex [nTPM]":"301.4","Tissue RNA - cervix [nTPM]":"8.4","Tissue RNA - choroid plexus [nTPM]":"82.1","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"8.2","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"7.9","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"14.0","Tissue RNA - hippocampal formation [nTPM]":"162.0","Tissue RNA - hypothalamus [nTPM]":"129.1","Tissue RNA - kidney [nTPM]":"32.1","Tissue RNA - liver [nTPM]":"4.1","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"122.8","Tissue RNA - midbrain [nTPM]":"153.6","Tissue RNA - ovary [nTPM]":"6.9","Tissue RNA - pancreas [nTPM]":"39.5","Tissue RNA - parathyroid gland [nTPM]":"6.9","Tissue RNA - pituitary gland [nTPM]":"42.8","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"123.9","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"84.4","Tissue RNA - salivary gland [nTPM]":"23.0","Tissue RNA - seminal vesicle [nTPM]":"7.4","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"3.1","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"134.6","Tissue RNA - spleen [nTPM]":"8.7","Tissue RNA - stomach 1 [nTPM]":"10.8","Tissue RNA - testis [nTPM]":"15.8","Tissue RNA - thalamus [nTPM]":"134.5","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"8.1","Tissue RNA - tonsil [nTPM]":"8.2","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"6.0","Tissue RNA - white matter [nTPM]":"164.8","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"3.5","Cell RNA - AF22 [nTPM]":"5.5","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"10.3","Cell RNA - ASC TERT1 [nTPM]":"2.2","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.2","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"5.9","Cell RNA - Daudi [nTPM]":"29.2","Cell RNA - EFO-21 [nTPM]":"9.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"3.9","Cell RNA - HBEC3-KT [nTPM]":"3.8","Cell RNA - HBF TERT88 [nTPM]":"1.5","Cell RNA - HDLM-2 [nTPM]":"7.7","Cell RNA - HEK 293 [nTPM]":"6.5","Cell RNA - HEL [nTPM]":"8.9","Cell RNA - HeLa [nTPM]":"22.5","Cell RNA - Hep G2 [nTPM]":"10.7","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"2.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"10.5","Cell RNA - K-562 [nTPM]":"18.9","Cell RNA - Karpas-707 [nTPM]":"29.1","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"2.7","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"1.9","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"4.2","Cell RNA - PC-3 [nTPM]":"4.5","Cell RNA - REH [nTPM]":"2.7","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"3.2","Cell RNA - RPTEC TERT1 [nTPM]":"11.2","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"13.4","Cell RNA - SiHa [nTPM]":"3.6","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"8.3","Cell RNA - SuSa [nTPM]":"12.4","Cell RNA - T-47d [nTPM]":"10.6","Cell RNA - THP-1 [nTPM]":"4.4","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"10.3","Cell RNA - U-266\/70 [nTPM]":"23.0","Cell RNA - U-266\/84 [nTPM]":"28.4","Cell RNA - U-698 [nTPM]":"18.8","Cell RNA - U-87 MG [nTPM]":"4.2","Cell RNA - U-937 [nTPM]":"7.7","Cell RNA - WM-115 [nTPM]":"3.2","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"9.3","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"6.9","Blood RNA - memory B-cell [nTPM]":"22.1","Blood RNA - memory CD4 T-cell [nTPM]":"9.7","Blood RNA - memory CD8 T-cell [nTPM]":"10.2","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"25.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.9","Blood RNA - naive CD8 T-cell [nTPM]":"8.1","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"9.5","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"7.2","Blood RNA - T-reg [nTPM]":"27.2","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"138.8","Brain RNA - basal ganglia [nTPM]":"157.7","Brain RNA - cerebellum [nTPM]":"115.9","Brain RNA - cerebral cortex [nTPM]":"301.4","Brain RNA - hippocampal formation [nTPM]":"162.0","Brain RNA - hypothalamus [nTPM]":"129.1","Brain RNA - medulla oblongata [nTPM]":"122.8","Brain RNA - midbrain [nTPM]":"153.6","Brain RNA - pons [nTPM]":"123.9","Brain RNA - spinal cord [nTPM]":"134.6","Brain RNA - thalamus [nTPM]":"134.5","Brain RNA - white matter [nTPM]":"164.8","Single Cell Type RNA - Adipocytes [nTPM]":"49.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"43.1","Single Cell Type RNA - B-cells [nTPM]":"10.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"219.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"6.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"16.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"176.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.0","Single Cell Type RNA - Fibroblasts [nTPM]":"8.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"228.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"73.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"78.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"174.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"14.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"54.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"27.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"6.2","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"SETX","Gene synonym":["ALS4","AOA2","KIAA0625","SCAR1","Sen1"],"Ensembl":"ENSG00000107290","Gene description":"Senataxin","Uniprot":["Q7Z333"],"Chromosome":"9","Position":"132261356-132354986","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Differentiation","DNA damage","DNA recombination","DNA repair","Neurogenesis","Spermatogenesis"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024105","HPA057269"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA024105":"AB_2671437","HPA057269":"AB_2683389"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.7","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"19.9","Tissue RNA - basal ganglia [nTPM]":"8.8","Tissue RNA - bone marrow [nTPM]":"16.8","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"9.8","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"13.2","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"10.6","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"11.1","Tissue RNA - esophagus [nTPM]":"10.6","Tissue RNA - fallopian tube [nTPM]":"10.9","Tissue RNA - gallbladder [nTPM]":"12.7","Tissue RNA - heart muscle [nTPM]":"10.5","Tissue RNA - hippocampal formation [nTPM]":"5.1","Tissue RNA - hypothalamus [nTPM]":"7.8","Tissue RNA - kidney [nTPM]":"11.9","Tissue RNA - liver [nTPM]":"16.7","Tissue RNA - lung [nTPM]":"15.4","Tissue RNA - lymph node [nTPM]":"27.4","Tissue RNA - medulla oblongata [nTPM]":"8.7","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"13.0","Tissue RNA - pancreas [nTPM]":"9.2","Tissue RNA - parathyroid gland [nTPM]":"18.3","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"14.3","Tissue RNA - pons [nTPM]":"9.6","Tissue RNA - prostate [nTPM]":"13.0","Tissue RNA - rectum [nTPM]":"12.8","Tissue RNA - retina [nTPM]":"13.2","Tissue RNA - salivary gland [nTPM]":"9.0","Tissue RNA - seminal vesicle [nTPM]":"12.7","Tissue RNA - skeletal muscle [nTPM]":"12.9","Tissue RNA - skin 1 [nTPM]":"12.3","Tissue RNA - small intestine [nTPM]":"13.2","Tissue RNA - smooth muscle [nTPM]":"12.8","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"27.6","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"31.9","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"25.4","Tissue RNA - thyroid gland [nTPM]":"33.0","Tissue RNA - tongue [nTPM]":"12.8","Tissue RNA - tonsil [nTPM]":"26.3","Tissue RNA - urinary bladder [nTPM]":"15.7","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"13.2","Cell RNA - A-431 [nTPM]":"15.1","Cell RNA - A549 [nTPM]":"19.9","Cell RNA - AF22 [nTPM]":"22.5","Cell RNA - AN3-CA [nTPM]":"24.4","Cell RNA - ASC diff [nTPM]":"28.3","Cell RNA - ASC TERT1 [nTPM]":"34.1","Cell RNA - BEWO [nTPM]":"13.5","Cell RNA - BJ [nTPM]":"19.6","Cell RNA - BJ hTERT+ [nTPM]":"21.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.6","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"16.8","Cell RNA - Daudi [nTPM]":"25.6","Cell RNA - EFO-21 [nTPM]":"9.4","Cell RNA - fHDF\/TERT166 [nTPM]":"36.9","Cell RNA - GAMG [nTPM]":"38.3","Cell RNA - HaCaT [nTPM]":"30.2","Cell RNA - HAP1 [nTPM]":"22.8","Cell RNA - HBEC3-KT [nTPM]":"17.0","Cell RNA - HBF TERT88 [nTPM]":"17.0","Cell RNA - HDLM-2 [nTPM]":"24.6","Cell RNA - HEK 293 [nTPM]":"9.9","Cell RNA - HEL [nTPM]":"26.9","Cell RNA - HeLa [nTPM]":"22.7","Cell RNA - Hep G2 [nTPM]":"18.4","Cell RNA - HHSteC [nTPM]":"26.5","Cell RNA - HL-60 [nTPM]":"41.8","Cell RNA - HMC-1 [nTPM]":"31.2","Cell RNA - HSkMC [nTPM]":"24.0","Cell RNA - hTCEpi [nTPM]":"26.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.6","Cell RNA - hTERT-HME1 [nTPM]":"23.6","Cell RNA - hTERT-RPE1 [nTPM]":"19.1","Cell RNA - HUVEC TERT2 [nTPM]":"25.4","Cell RNA - JURKAT [nTPM]":"17.8","Cell RNA - K-562 [nTPM]":"31.7","Cell RNA - Karpas-707 [nTPM]":"20.0","Cell RNA - LHCN-M2 [nTPM]":"18.3","Cell RNA - MCF7 [nTPM]":"21.8","Cell RNA - MOLT-4 [nTPM]":"25.9","Cell RNA - NB-4 [nTPM]":"15.8","Cell RNA - NTERA-2 [nTPM]":"24.2","Cell RNA - OE19 [nTPM]":"25.4","Cell RNA - PC-3 [nTPM]":"15.4","Cell RNA - REH [nTPM]":"24.2","Cell RNA - RH-30 [nTPM]":"32.6","Cell RNA - RPMI-8226 [nTPM]":"17.2","Cell RNA - RPTEC TERT1 [nTPM]":"17.1","Cell RNA - RT4 [nTPM]":"19.5","Cell RNA - SCLC-21H [nTPM]":"14.0","Cell RNA - SH-SY5Y [nTPM]":"21.4","Cell RNA - SiHa [nTPM]":"32.4","Cell RNA - SK-BR-3 [nTPM]":"14.2","Cell RNA - SK-MEL-30 [nTPM]":"18.2","Cell RNA - SuSa [nTPM]":"29.7","Cell RNA - T-47d [nTPM]":"19.7","Cell RNA - THP-1 [nTPM]":"21.2","Cell RNA - TIME [nTPM]":"29.3","Cell RNA - U-138 MG [nTPM]":"32.5","Cell RNA - U-2 OS [nTPM]":"14.0","Cell RNA - U-2197 [nTPM]":"22.1","Cell RNA - U-251 MG [nTPM]":"19.0","Cell RNA - U-266\/70 [nTPM]":"12.2","Cell RNA - U-266\/84 [nTPM]":"22.0","Cell RNA - U-698 [nTPM]":"38.6","Cell RNA - U-87 MG [nTPM]":"14.9","Cell RNA - U-937 [nTPM]":"16.3","Cell RNA - WM-115 [nTPM]":"17.8","Blood RNA - basophil [nTPM]":"10.5","Blood RNA - classical monocyte [nTPM]":"4.4","Blood RNA - eosinophil [nTPM]":"4.7","Blood RNA - gdT-cell [nTPM]":"5.3","Blood RNA - intermediate monocyte [nTPM]":"4.1","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"5.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.9","Blood RNA - memory CD8 T-cell [nTPM]":"4.1","Blood RNA - myeloid DC [nTPM]":"3.3","Blood RNA - naive B-cell [nTPM]":"6.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.2","Blood RNA - naive CD8 T-cell [nTPM]":"3.7","Blood RNA - neutrophil [nTPM]":"15.1","Blood RNA - NK-cell [nTPM]":"5.2","Blood RNA - non-classical monocyte [nTPM]":"4.9","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"8.8","Brain RNA - cerebellum [nTPM]":"9.8","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"5.1","Brain RNA - hypothalamus [nTPM]":"7.8","Brain RNA - medulla oblongata [nTPM]":"8.7","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"9.6","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"13.2","Single Cell Type RNA - Adipocytes [nTPM]":"76.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.7","Single Cell Type RNA - Astrocytes [nTPM]":"75.1","Single Cell Type RNA - B-cells [nTPM]":"85.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.7","Single Cell Type RNA - Bipolar cells [nTPM]":"31.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"43.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.7","Single Cell Type RNA - dendritic cells [nTPM]":"96.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"20.0","Single Cell Type RNA - Early spermatids [nTPM]":"7.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"68.0","Single Cell Type RNA - Endothelial cells [nTPM]":"58.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.5","Single Cell Type RNA - Erythroid cells [nTPM]":"25.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"73.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.6","Single Cell Type RNA - Fibroblasts [nTPM]":"52.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"89.7","Single Cell Type RNA - granulocytes [nTPM]":"58.2","Single Cell Type RNA - Granulosa cells [nTPM]":"38.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"51.4","Single Cell Type RNA - Hepatocytes [nTPM]":"33.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.8","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"64.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"73.1","Single Cell Type RNA - Langerhans cells [nTPM]":"37.6","Single Cell Type RNA - Late spermatids [nTPM]":"13.8","Single Cell Type RNA - Leydig cells [nTPM]":"30.7","Single Cell Type RNA - Macrophages [nTPM]":"75.5","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"131.2","Single Cell Type RNA - monocytes [nTPM]":"75.8","Single Cell Type RNA - Muller glia cells [nTPM]":"20.7","Single Cell Type RNA - NK-cells [nTPM]":"87.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"65.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"113.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.2","Single Cell Type RNA - Paneth cells [nTPM]":"31.9","Single Cell Type RNA - Peritubular cells [nTPM]":"36.1","Single Cell Type RNA - Plasma cells [nTPM]":"61.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"49.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"54.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"42.5","Single Cell Type RNA - Spermatocytes [nTPM]":"145.2","Single Cell Type RNA - Spermatogonia [nTPM]":"38.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - T-cells [nTPM]":"65.9","Single Cell Type RNA - Theca cells [nTPM]":"53.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.9","Single Cell Type RNA - Urothelial cells [nTPM]":"46.4"},{"Gene":"SGCE","Gene synonym":["DYT11"],"Ensembl":"ENSG00000127990","Gene description":"Sarcoglycan epsilon","Uniprot":["O43556"],"Chromosome":"7","Position":"94524204-94656572","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"116.6","Oligodendrocyte precursor cells":"133.2","Oligodendrocytes":"116.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"2.1","memory B-cell":"4.4","naive B-cell":"6.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"6.6","T-cells":"2.1"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074790"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Golgi apparatus"],"Antibody RRID":{"HPA074790":"AB_2686713"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"43.2","Tissue RNA - adrenal gland [nTPM]":"63.4","Tissue RNA - amygdala [nTPM]":"19.9","Tissue RNA - appendix [nTPM]":"9.4","Tissue RNA - basal ganglia [nTPM]":"21.6","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"36.5","Tissue RNA - cerebellum [nTPM]":"22.1","Tissue RNA - cerebral cortex [nTPM]":"31.6","Tissue RNA - cervix [nTPM]":"45.1","Tissue RNA - choroid plexus [nTPM]":"20.9","Tissue RNA - colon [nTPM]":"51.6","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"43.2","Tissue RNA - epididymis [nTPM]":"27.1","Tissue RNA - esophagus [nTPM]":"13.3","Tissue RNA - fallopian tube [nTPM]":"40.7","Tissue RNA - gallbladder [nTPM]":"27.6","Tissue RNA - heart muscle [nTPM]":"38.9","Tissue RNA - hippocampal formation [nTPM]":"19.6","Tissue RNA - hypothalamus [nTPM]":"21.0","Tissue RNA - kidney [nTPM]":"19.5","Tissue RNA - liver [nTPM]":"14.4","Tissue RNA - lung [nTPM]":"30.5","Tissue RNA - lymph node [nTPM]":"16.7","Tissue RNA - medulla oblongata [nTPM]":"23.2","Tissue RNA - midbrain [nTPM]":"20.6","Tissue RNA - ovary [nTPM]":"92.2","Tissue RNA - pancreas [nTPM]":"21.5","Tissue RNA - parathyroid gland [nTPM]":"10.9","Tissue RNA - pituitary gland [nTPM]":"30.9","Tissue RNA - placenta [nTPM]":"52.7","Tissue RNA - pons [nTPM]":"22.4","Tissue RNA - prostate [nTPM]":"18.0","Tissue RNA - rectum [nTPM]":"12.8","Tissue RNA - retina [nTPM]":"16.8","Tissue RNA - salivary gland [nTPM]":"21.1","Tissue RNA - seminal vesicle [nTPM]":"31.6","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"8.2","Tissue RNA - small intestine [nTPM]":"19.2","Tissue RNA - smooth muscle [nTPM]":"41.8","Tissue RNA - spinal cord [nTPM]":"21.9","Tissue RNA - spleen [nTPM]":"25.1","Tissue RNA - stomach 1 [nTPM]":"23.8","Tissue RNA - testis [nTPM]":"18.5","Tissue RNA - thalamus [nTPM]":"20.4","Tissue RNA - thymus [nTPM]":"12.8","Tissue RNA - thyroid gland [nTPM]":"23.9","Tissue RNA - tongue [nTPM]":"19.8","Tissue RNA - tonsil [nTPM]":"7.2","Tissue RNA - urinary bladder [nTPM]":"35.6","Tissue RNA - vagina [nTPM]":"34.6","Tissue RNA - white matter [nTPM]":"26.7","Cell RNA - A-431 [nTPM]":"13.5","Cell RNA - A549 [nTPM]":"42.5","Cell RNA - AF22 [nTPM]":"39.6","Cell RNA - AN3-CA [nTPM]":"61.8","Cell RNA - ASC diff [nTPM]":"63.7","Cell RNA - ASC TERT1 [nTPM]":"110.8","Cell RNA - BEWO [nTPM]":"7.1","Cell RNA - BJ [nTPM]":"51.3","Cell RNA - BJ hTERT+ [nTPM]":"92.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"60.4","Cell RNA - CACO-2 [nTPM]":"24.9","Cell RNA - CAPAN-2 [nTPM]":"78.0","Cell RNA - Daudi [nTPM]":"12.8","Cell RNA - EFO-21 [nTPM]":"70.4","Cell RNA - fHDF\/TERT166 [nTPM]":"86.5","Cell RNA - GAMG [nTPM]":"83.7","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"60.0","Cell RNA - HBEC3-KT [nTPM]":"21.6","Cell RNA - HBF TERT88 [nTPM]":"49.1","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"32.7","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"36.9","Cell RNA - Hep G2 [nTPM]":"28.3","Cell RNA - HHSteC [nTPM]":"44.0","Cell RNA - HL-60 [nTPM]":"4.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"95.5","Cell RNA - hTCEpi [nTPM]":"31.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.8","Cell RNA - hTERT-HME1 [nTPM]":"79.3","Cell RNA - hTERT-RPE1 [nTPM]":"104.9","Cell RNA - HUVEC TERT2 [nTPM]":"30.8","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"93.7","Cell RNA - LHCN-M2 [nTPM]":"43.5","Cell RNA - MCF7 [nTPM]":"42.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"32.8","Cell RNA - OE19 [nTPM]":"8.0","Cell RNA - PC-3 [nTPM]":"29.0","Cell RNA - REH [nTPM]":"19.8","Cell RNA - RH-30 [nTPM]":"51.0","Cell RNA - RPMI-8226 [nTPM]":"25.8","Cell RNA - RPTEC TERT1 [nTPM]":"78.6","Cell RNA - RT4 [nTPM]":"13.6","Cell RNA - SCLC-21H [nTPM]":"26.2","Cell RNA - SH-SY5Y [nTPM]":"20.8","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"52.2","Cell RNA - SK-MEL-30 [nTPM]":"65.1","Cell RNA - SuSa [nTPM]":"44.2","Cell RNA - T-47d [nTPM]":"17.6","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"131.1","Cell RNA - U-2 OS [nTPM]":"45.1","Cell RNA - U-2197 [nTPM]":"11.8","Cell RNA - U-251 MG [nTPM]":"81.7","Cell RNA - U-266\/70 [nTPM]":"50.8","Cell RNA - U-266\/84 [nTPM]":"67.9","Cell RNA - U-698 [nTPM]":"14.8","Cell RNA - U-87 MG [nTPM]":"51.4","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"74.2","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"2.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"6.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"19.9","Brain RNA - basal ganglia [nTPM]":"21.6","Brain RNA - cerebellum [nTPM]":"22.1","Brain RNA - cerebral cortex [nTPM]":"31.6","Brain RNA - hippocampal formation [nTPM]":"19.6","Brain RNA - hypothalamus [nTPM]":"21.0","Brain RNA - medulla oblongata [nTPM]":"23.2","Brain RNA - midbrain [nTPM]":"20.6","Brain RNA - pons [nTPM]":"22.4","Brain RNA - spinal cord [nTPM]":"21.9","Brain RNA - thalamus [nTPM]":"20.4","Brain RNA - white matter [nTPM]":"26.7","Single Cell Type RNA - Adipocytes [nTPM]":"39.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.3","Single Cell Type RNA - Astrocytes [nTPM]":"66.9","Single Cell Type RNA - B-cells [nTPM]":"6.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"18.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"44.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"28.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"90.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"42.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"85.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.1","Single Cell Type RNA - Fibroblasts [nTPM]":"116.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.6","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"37.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"58.2","Single Cell Type RNA - Hepatocytes [nTPM]":"11.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.3","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"68.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"75.5","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"31.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"133.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"116.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"58.3","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.3","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"68.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"60.7","Single Cell Type RNA - Spermatocytes [nTPM]":"17.1","Single Cell Type RNA - Spermatogonia [nTPM]":"13.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"82.8","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"44.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"SH3TC2","Gene synonym":["CMT4C","KIAA1985"],"Ensembl":"ENSG00000169247","Gene description":"SH3 domain and tetratricopeptide repeats 2","Uniprot":["Q8TF17"],"Chromosome":"5","Position":"148923639-149063163","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"12.6","retina":"3.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Oligodendrocytes":"270.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"2.6","HBEC3-KT":"2.2","RT4":"3.6","SK-MEL-30":"5.2","WM-115":"3.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037683","HPA037684"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA037683":"AB_2675608","HPA037684":"AB_10672603"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"4.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"5.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"7.1","Tissue RNA - midbrain [nTPM]":"6.9","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"5.8","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"12.6","Cell RNA - A-431 [nTPM]":"1.8","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"2.6","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"1.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"3.6","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"5.2","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"1.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"3.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.7","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"5.0","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"7.1","Brain RNA - midbrain [nTPM]":"6.9","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"5.8","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"12.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"6.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"2.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"2.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"270.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"8.8"},{"Gene":"SIGMAR1","Gene synonym":["OPRS1","SR-BP1"],"Ensembl":"ENSG00000147955","Gene description":"Sigma non-opioid intracellular receptor 1","Uniprot":["Q99720"],"Chromosome":"9","Position":"34634722-34637844","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"187.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"98.7","Hepatocytes":"97.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013470","HPA018002","HPA024071"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013470":"AB_2533521","HPA018002":"AB_1854802","HPA024071":"AB_1854803"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.42e-4"},"Tissue RNA - adipose tissue [nTPM]":"42.0","Tissue RNA - adrenal gland [nTPM]":"52.4","Tissue RNA - amygdala [nTPM]":"25.2","Tissue RNA - appendix [nTPM]":"19.4","Tissue RNA - basal ganglia [nTPM]":"25.3","Tissue RNA - bone marrow [nTPM]":"20.5","Tissue RNA - breast [nTPM]":"38.1","Tissue RNA - cerebellum [nTPM]":"26.2","Tissue RNA - cerebral cortex [nTPM]":"27.1","Tissue RNA - cervix [nTPM]":"53.0","Tissue RNA - choroid plexus [nTPM]":"27.4","Tissue RNA - colon [nTPM]":"42.0","Tissue RNA - duodenum [nTPM]":"46.0","Tissue RNA - endometrium 1 [nTPM]":"50.7","Tissue RNA - epididymis [nTPM]":"45.0","Tissue RNA - esophagus [nTPM]":"54.1","Tissue RNA - fallopian tube [nTPM]":"46.9","Tissue RNA - gallbladder [nTPM]":"22.1","Tissue RNA - heart muscle [nTPM]":"34.0","Tissue RNA - hippocampal formation [nTPM]":"25.8","Tissue RNA - hypothalamus [nTPM]":"30.2","Tissue RNA - kidney [nTPM]":"25.5","Tissue RNA - liver [nTPM]":"187.6","Tissue RNA - lung [nTPM]":"27.5","Tissue RNA - lymph node [nTPM]":"16.9","Tissue RNA - medulla oblongata [nTPM]":"28.3","Tissue RNA - midbrain [nTPM]":"28.7","Tissue RNA - ovary [nTPM]":"46.1","Tissue RNA - pancreas [nTPM]":"45.7","Tissue RNA - parathyroid gland [nTPM]":"39.0","Tissue RNA - pituitary gland [nTPM]":"22.0","Tissue RNA - placenta [nTPM]":"27.6","Tissue RNA - pons [nTPM]":"29.4","Tissue RNA - prostate [nTPM]":"35.5","Tissue RNA - rectum [nTPM]":"31.2","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"35.0","Tissue RNA - seminal vesicle [nTPM]":"38.5","Tissue RNA - skeletal muscle [nTPM]":"17.6","Tissue RNA - skin 1 [nTPM]":"53.9","Tissue RNA - small intestine [nTPM]":"40.0","Tissue RNA - smooth muscle [nTPM]":"34.8","Tissue RNA - spinal cord [nTPM]":"26.2","Tissue RNA - spleen [nTPM]":"24.2","Tissue RNA - stomach 1 [nTPM]":"42.1","Tissue RNA - testis [nTPM]":"20.2","Tissue RNA - thalamus [nTPM]":"33.3","Tissue RNA - thymus [nTPM]":"19.1","Tissue RNA - thyroid gland [nTPM]":"29.7","Tissue RNA - tongue [nTPM]":"13.5","Tissue RNA - tonsil [nTPM]":"22.2","Tissue RNA - urinary bladder [nTPM]":"46.3","Tissue RNA - vagina [nTPM]":"43.5","Tissue RNA - white matter [nTPM]":"27.1","Cell RNA - A-431 [nTPM]":"184.3","Cell RNA - A549 [nTPM]":"162.6","Cell RNA - AF22 [nTPM]":"59.8","Cell RNA - AN3-CA [nTPM]":"175.3","Cell RNA - ASC diff [nTPM]":"205.7","Cell RNA - ASC TERT1 [nTPM]":"138.7","Cell RNA - BEWO [nTPM]":"66.5","Cell RNA - BJ [nTPM]":"127.1","Cell RNA - BJ hTERT+ [nTPM]":"91.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"115.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"105.9","Cell RNA - CACO-2 [nTPM]":"97.6","Cell RNA - CAPAN-2 [nTPM]":"76.8","Cell RNA - Daudi [nTPM]":"87.8","Cell RNA - EFO-21 [nTPM]":"71.9","Cell RNA - fHDF\/TERT166 [nTPM]":"151.7","Cell RNA - GAMG [nTPM]":"69.8","Cell RNA - HaCaT [nTPM]":"108.8","Cell RNA - HAP1 [nTPM]":"94.5","Cell RNA - HBEC3-KT [nTPM]":"151.3","Cell RNA - HBF TERT88 [nTPM]":"57.8","Cell RNA - HDLM-2 [nTPM]":"144.7","Cell RNA - HEK 293 [nTPM]":"175.6","Cell RNA - HEL [nTPM]":"78.0","Cell RNA - HeLa [nTPM]":"225.0","Cell RNA - Hep G2 [nTPM]":"112.7","Cell RNA - HHSteC [nTPM]":"131.7","Cell RNA - HL-60 [nTPM]":"145.0","Cell RNA - HMC-1 [nTPM]":"67.6","Cell RNA - HSkMC [nTPM]":"142.9","Cell RNA - hTCEpi [nTPM]":"163.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"131.2","Cell RNA - hTERT-HME1 [nTPM]":"197.7","Cell RNA - hTERT-RPE1 [nTPM]":"59.4","Cell RNA - HUVEC TERT2 [nTPM]":"90.2","Cell RNA - JURKAT [nTPM]":"114.5","Cell RNA - K-562 [nTPM]":"30.1","Cell RNA - Karpas-707 [nTPM]":"156.2","Cell RNA - LHCN-M2 [nTPM]":"139.7","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"88.2","Cell RNA - NB-4 [nTPM]":"215.2","Cell RNA - NTERA-2 [nTPM]":"68.8","Cell RNA - OE19 [nTPM]":"101.5","Cell RNA - PC-3 [nTPM]":"184.4","Cell RNA - REH [nTPM]":"101.4","Cell RNA - RH-30 [nTPM]":"59.6","Cell RNA - RPMI-8226 [nTPM]":"258.3","Cell RNA - RPTEC TERT1 [nTPM]":"111.0","Cell RNA - RT4 [nTPM]":"36.5","Cell RNA - SCLC-21H [nTPM]":"57.6","Cell RNA - SH-SY5Y [nTPM]":"65.5","Cell RNA - SiHa [nTPM]":"123.3","Cell RNA - SK-BR-3 [nTPM]":"89.5","Cell RNA - SK-MEL-30 [nTPM]":"70.0","Cell RNA - SuSa [nTPM]":"32.0","Cell RNA - T-47d [nTPM]":"106.9","Cell RNA - THP-1 [nTPM]":"98.7","Cell RNA - TIME [nTPM]":"68.5","Cell RNA - U-138 MG [nTPM]":"90.0","Cell RNA - U-2 OS [nTPM]":"69.9","Cell RNA - U-2197 [nTPM]":"96.4","Cell RNA - U-251 MG [nTPM]":"19.2","Cell RNA - U-266\/70 [nTPM]":"43.2","Cell RNA - U-266\/84 [nTPM]":"71.6","Cell RNA - U-698 [nTPM]":"2.5","Cell RNA - U-87 MG [nTPM]":"97.2","Cell RNA - U-937 [nTPM]":"123.9","Cell RNA - WM-115 [nTPM]":"191.8","Blood RNA - basophil [nTPM]":"24.3","Blood RNA - classical monocyte [nTPM]":"39.5","Blood RNA - eosinophil [nTPM]":"24.2","Blood RNA - gdT-cell [nTPM]":"43.0","Blood RNA - intermediate monocyte [nTPM]":"39.3","Blood RNA - MAIT T-cell [nTPM]":"46.2","Blood RNA - memory B-cell [nTPM]":"26.5","Blood RNA - memory CD4 T-cell [nTPM]":"62.5","Blood RNA - memory CD8 T-cell [nTPM]":"51.3","Blood RNA - myeloid DC [nTPM]":"48.9","Blood RNA - naive B-cell [nTPM]":"21.1","Blood RNA - naive CD4 T-cell [nTPM]":"51.7","Blood RNA - naive CD8 T-cell [nTPM]":"43.6","Blood RNA - neutrophil [nTPM]":"10.7","Blood RNA - NK-cell [nTPM]":"28.7","Blood RNA - non-classical monocyte [nTPM]":"42.5","Blood RNA - plasmacytoid DC [nTPM]":"35.1","Blood RNA - T-reg [nTPM]":"65.5","Blood RNA - total PBMC [nTPM]":"43.5","Brain RNA - amygdala [nTPM]":"25.2","Brain RNA - basal ganglia [nTPM]":"25.3","Brain RNA - cerebellum [nTPM]":"26.2","Brain RNA - cerebral cortex [nTPM]":"27.1","Brain RNA - hippocampal formation [nTPM]":"25.8","Brain RNA - hypothalamus [nTPM]":"30.2","Brain RNA - medulla oblongata [nTPM]":"28.3","Brain RNA - midbrain [nTPM]":"28.7","Brain RNA - pons [nTPM]":"29.4","Brain RNA - spinal cord [nTPM]":"26.2","Brain RNA - thalamus [nTPM]":"33.3","Brain RNA - white matter [nTPM]":"27.1","Single Cell Type RNA - Adipocytes [nTPM]":"11.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"12.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"10.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"12.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.8","Single Cell Type RNA - dendritic cells [nTPM]":"10.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"33.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.7","Single Cell Type RNA - Endothelial cells [nTPM]":"14.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"23.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"98.7","Single Cell Type RNA - Fibroblasts [nTPM]":"29.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.1","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"19.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"97.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"27.4","Single Cell Type RNA - Macrophages [nTPM]":"10.8","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"9.5","Single Cell Type RNA - Muller glia cells [nTPM]":"13.8","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.1","Single Cell Type RNA - Paneth cells [nTPM]":"31.5","Single Cell Type RNA - Peritubular cells [nTPM]":"25.6","Single Cell Type RNA - Plasma cells [nTPM]":"22.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"58.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.9","Single Cell Type RNA - Spermatocytes [nTPM]":"6.0","Single Cell Type RNA - Spermatogonia [nTPM]":"10.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.5","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"26.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.3","Single Cell Type RNA - Urothelial cells [nTPM]":"16.1"},{"Gene":"SIK1","Gene synonym":["msk","SNF1LK"],"Ensembl":"ENSG00000142178","Gene description":"Salt inducible kinase 1","Uniprot":["P57059"],"Chromosome":"21","Position":"43414483-43427131","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","Cell cycle","Differentiation"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"88.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"302.0","Basal respiratory cells":"123.5","Langerhans cells":"141.9","Suprabasal keratinocytes":"422.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"35.3","HeLa":"63.1","hTCEpi":"45.4","LHCN-M2":"45.5","U-266\/84":"37.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB023801","HPA038211","HPA078064"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB023801":null,"HPA038211":"AB_2675894","HPA078064":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.5","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"10.5","Tissue RNA - breast [nTPM]":"19.5","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"18.5","Tissue RNA - fallopian tube [nTPM]":"18.6","Tissue RNA - gallbladder [nTPM]":"15.1","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"20.9","Tissue RNA - lung [nTPM]":"12.7","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"26.9","Tissue RNA - pancreas [nTPM]":"11.8","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"12.5","Tissue RNA - placenta [nTPM]":"12.5","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"9.2","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"13.0","Tissue RNA - skin 1 [nTPM]":"88.0","Tissue RNA - small intestine [nTPM]":"5.4","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"12.2","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"6.2","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"16.9","Tissue RNA - vagina [nTPM]":"14.4","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"1.2","Cell RNA - A549 [nTPM]":"3.4","Cell RNA - AF22 [nTPM]":"4.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"1.6","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"2.0","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.7","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"5.4","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"19.8","Cell RNA - HaCaT [nTPM]":"23.6","Cell RNA - HAP1 [nTPM]":"3.5","Cell RNA - HBEC3-KT [nTPM]":"35.3","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"63.1","Cell RNA - Hep G2 [nTPM]":"2.0","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"1.7","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"45.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"10.7","Cell RNA - hTERT-RPE1 [nTPM]":"20.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"45.5","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"3.9","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"5.7","Cell RNA - RPTEC TERT1 [nTPM]":"4.0","Cell RNA - RT4 [nTPM]":"13.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"24.2","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"2.3","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"8.1","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"9.5","Cell RNA - U-266\/84 [nTPM]":"37.7","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"10.0","Cell RNA - U-937 [nTPM]":"4.6","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"77.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"18.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"302.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"123.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"68.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"13.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.8","Single Cell Type RNA - Endothelial cells [nTPM]":"18.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"11.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.1","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.5","Single Cell Type RNA - Ionocytes [nTPM]":"85.5","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"141.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"10.1","Single Cell Type RNA - Melanocytes [nTPM]":"96.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.3","Single Cell Type RNA - Paneth cells [nTPM]":"24.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"36.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"422.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"16.4","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"SIL1","Gene synonym":["BAP","MSS","ULG5"],"Ensembl":"ENSG00000120725","Gene description":"SIL1 nucleotide exchange factor","Uniprot":["Q9H173"],"Chromosome":"5","Position":"138946724-139293557","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"195.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011949"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"710000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011949":"AB_1856875"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.34e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"26.4","Tissue RNA - adrenal gland [nTPM]":"46.4","Tissue RNA - amygdala [nTPM]":"9.0","Tissue RNA - appendix [nTPM]":"19.7","Tissue RNA - basal ganglia [nTPM]":"10.6","Tissue RNA - bone marrow [nTPM]":"24.1","Tissue RNA - breast [nTPM]":"21.6","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"11.8","Tissue RNA - cervix [nTPM]":"21.7","Tissue RNA - choroid plexus [nTPM]":"17.9","Tissue RNA - colon [nTPM]":"20.0","Tissue RNA - duodenum [nTPM]":"24.6","Tissue RNA - endometrium 1 [nTPM]":"21.7","Tissue RNA - epididymis [nTPM]":"32.5","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"19.2","Tissue RNA - gallbladder [nTPM]":"23.2","Tissue RNA - heart muscle [nTPM]":"29.5","Tissue RNA - hippocampal formation [nTPM]":"9.2","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"20.9","Tissue RNA - liver [nTPM]":"54.9","Tissue RNA - lung [nTPM]":"22.6","Tissue RNA - lymph node [nTPM]":"14.1","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"19.1","Tissue RNA - pancreas [nTPM]":"67.7","Tissue RNA - parathyroid gland [nTPM]":"33.7","Tissue RNA - pituitary gland [nTPM]":"28.5","Tissue RNA - placenta [nTPM]":"28.7","Tissue RNA - pons [nTPM]":"10.5","Tissue RNA - prostate [nTPM]":"23.9","Tissue RNA - rectum [nTPM]":"12.8","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"36.7","Tissue RNA - seminal vesicle [nTPM]":"25.8","Tissue RNA - skeletal muscle [nTPM]":"41.4","Tissue RNA - skin 1 [nTPM]":"23.2","Tissue RNA - small intestine [nTPM]":"16.4","Tissue RNA - smooth muscle [nTPM]":"17.2","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"17.3","Tissue RNA - stomach 1 [nTPM]":"29.5","Tissue RNA - testis [nTPM]":"49.8","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"9.0","Tissue RNA - thyroid gland [nTPM]":"36.2","Tissue RNA - tongue [nTPM]":"18.0","Tissue RNA - tonsil [nTPM]":"10.0","Tissue RNA - urinary bladder [nTPM]":"20.6","Tissue RNA - vagina [nTPM]":"16.2","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"33.7","Cell RNA - A549 [nTPM]":"34.9","Cell RNA - AF22 [nTPM]":"11.3","Cell RNA - AN3-CA [nTPM]":"56.2","Cell RNA - ASC diff [nTPM]":"84.0","Cell RNA - ASC TERT1 [nTPM]":"48.3","Cell RNA - BEWO [nTPM]":"65.0","Cell RNA - BJ [nTPM]":"54.0","Cell RNA - BJ hTERT+ [nTPM]":"58.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"57.3","Cell RNA - CACO-2 [nTPM]":"36.9","Cell RNA - CAPAN-2 [nTPM]":"78.9","Cell RNA - Daudi [nTPM]":"12.4","Cell RNA - EFO-21 [nTPM]":"89.7","Cell RNA - fHDF\/TERT166 [nTPM]":"74.2","Cell RNA - GAMG [nTPM]":"32.2","Cell RNA - HaCaT [nTPM]":"29.8","Cell RNA - HAP1 [nTPM]":"12.0","Cell RNA - HBEC3-KT [nTPM]":"76.0","Cell RNA - HBF TERT88 [nTPM]":"15.8","Cell RNA - HDLM-2 [nTPM]":"33.7","Cell RNA - HEK 293 [nTPM]":"20.7","Cell RNA - HEL [nTPM]":"16.4","Cell RNA - HeLa [nTPM]":"23.9","Cell RNA - Hep G2 [nTPM]":"40.9","Cell RNA - HHSteC [nTPM]":"67.2","Cell RNA - HL-60 [nTPM]":"4.9","Cell RNA - HMC-1 [nTPM]":"72.6","Cell RNA - HSkMC [nTPM]":"60.7","Cell RNA - hTCEpi [nTPM]":"73.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.4","Cell RNA - hTERT-HME1 [nTPM]":"79.0","Cell RNA - hTERT-RPE1 [nTPM]":"42.7","Cell RNA - HUVEC TERT2 [nTPM]":"40.5","Cell RNA - JURKAT [nTPM]":"15.4","Cell RNA - K-562 [nTPM]":"8.7","Cell RNA - Karpas-707 [nTPM]":"131.3","Cell RNA - LHCN-M2 [nTPM]":"32.2","Cell RNA - MCF7 [nTPM]":"52.1","Cell RNA - MOLT-4 [nTPM]":"12.4","Cell RNA - NB-4 [nTPM]":"15.1","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"38.6","Cell RNA - PC-3 [nTPM]":"4.2","Cell RNA - REH [nTPM]":"8.9","Cell RNA - RH-30 [nTPM]":"7.8","Cell RNA - RPMI-8226 [nTPM]":"92.7","Cell RNA - RPTEC TERT1 [nTPM]":"38.9","Cell RNA - RT4 [nTPM]":"17.7","Cell RNA - SCLC-21H [nTPM]":"19.5","Cell RNA - SH-SY5Y [nTPM]":"13.0","Cell RNA - SiHa [nTPM]":"46.3","Cell RNA - SK-BR-3 [nTPM]":"44.3","Cell RNA - SK-MEL-30 [nTPM]":"74.5","Cell RNA - SuSa [nTPM]":"24.8","Cell RNA - T-47d [nTPM]":"38.4","Cell RNA - THP-1 [nTPM]":"30.6","Cell RNA - TIME [nTPM]":"30.6","Cell RNA - U-138 MG [nTPM]":"46.8","Cell RNA - U-2 OS [nTPM]":"10.9","Cell RNA - U-2197 [nTPM]":"17.9","Cell RNA - U-251 MG [nTPM]":"23.6","Cell RNA - U-266\/70 [nTPM]":"56.3","Cell RNA - U-266\/84 [nTPM]":"31.6","Cell RNA - U-698 [nTPM]":"8.2","Cell RNA - U-87 MG [nTPM]":"34.3","Cell RNA - U-937 [nTPM]":"38.1","Cell RNA - WM-115 [nTPM]":"39.9","Blood RNA - basophil [nTPM]":"18.1","Blood RNA - classical monocyte [nTPM]":"47.7","Blood RNA - eosinophil [nTPM]":"19.4","Blood RNA - gdT-cell [nTPM]":"17.4","Blood RNA - intermediate monocyte [nTPM]":"52.4","Blood RNA - MAIT T-cell [nTPM]":"10.9","Blood RNA - memory B-cell [nTPM]":"20.1","Blood RNA - memory CD4 T-cell [nTPM]":"12.1","Blood RNA - memory CD8 T-cell [nTPM]":"16.8","Blood RNA - myeloid DC [nTPM]":"51.3","Blood RNA - naive B-cell [nTPM]":"14.7","Blood RNA - naive CD4 T-cell [nTPM]":"12.1","Blood RNA - naive CD8 T-cell [nTPM]":"15.1","Blood RNA - neutrophil [nTPM]":"5.7","Blood RNA - NK-cell [nTPM]":"22.1","Blood RNA - non-classical monocyte [nTPM]":"42.3","Blood RNA - plasmacytoid DC [nTPM]":"37.3","Blood RNA - T-reg [nTPM]":"11.7","Blood RNA - total PBMC [nTPM]":"27.1","Brain RNA - amygdala [nTPM]":"9.0","Brain RNA - basal ganglia [nTPM]":"10.6","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"11.8","Brain RNA - hippocampal formation [nTPM]":"9.2","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"10.5","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"22.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.0","Single Cell Type RNA - Astrocytes [nTPM]":"51.6","Single Cell Type RNA - B-cells [nTPM]":"32.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"61.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"9.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"48.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"121.2","Single Cell Type RNA - dendritic cells [nTPM]":"19.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"61.8","Single Cell Type RNA - Early spermatids [nTPM]":"109.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.0","Single Cell Type RNA - Endothelial cells [nTPM]":"21.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.5","Single Cell Type RNA - Erythroid cells [nTPM]":"7.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"75.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"81.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"104.2","Single Cell Type RNA - Fibroblasts [nTPM]":"46.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.1","Single Cell Type RNA - granulocytes [nTPM]":"60.3","Single Cell Type RNA - Granulosa cells [nTPM]":"29.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.3","Single Cell Type RNA - Hepatocytes [nTPM]":"143.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"70.3","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"73.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"64.3","Single Cell Type RNA - Ionocytes [nTPM]":"52.9","Single Cell Type RNA - Kupffer cells [nTPM]":"33.9","Single Cell Type RNA - Langerhans cells [nTPM]":"21.0","Single Cell Type RNA - Late spermatids [nTPM]":"195.7","Single Cell Type RNA - Leydig cells [nTPM]":"28.6","Single Cell Type RNA - Macrophages [nTPM]":"36.7","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"113.8","Single Cell Type RNA - Muller glia cells [nTPM]":"15.2","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"57.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"46.2","Single Cell Type RNA - Paneth cells [nTPM]":"34.9","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"114.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"51.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.7","Single Cell Type RNA - Spermatocytes [nTPM]":"96.9","Single Cell Type RNA - Spermatogonia [nTPM]":"61.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"153.6","Single Cell Type RNA - T-cells [nTPM]":"16.9","Single Cell Type RNA - Theca cells [nTPM]":"60.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.0","Single Cell Type RNA - Urothelial cells [nTPM]":"30.1"},{"Gene":"SIPA1L3","Gene synonym":["KIAA0545","SPAR3"],"Ensembl":"ENSG00000105738","Gene description":"Signal induced proliferation associated 1 like 3","Uniprot":["O60292"],"Chromosome":"19","Position":"37907208-38208369","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"93.7","Inhibitory neurons":"87.3","Oligodendrocyte precursor cells":"99.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"59.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042072","HPA045480","HPA074988"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Golgi apparatus"],"Antibody RRID":{"HPA042072":"AB_2677832","HPA045480":"AB_2679342","HPA074988":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.2","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"6.0","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"5.1","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"16.2","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"2.6","Tissue RNA - colon [nTPM]":"10.6","Tissue RNA - duodenum [nTPM]":"18.4","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"28.9","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"3.4","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"6.8","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"9.7","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"3.5","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"6.5","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"18.1","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"7.3","Tissue RNA - stomach 1 [nTPM]":"9.1","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"5.6","Tissue RNA - thymus [nTPM]":"3.8","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"5.5","Tissue RNA - urinary bladder [nTPM]":"4.3","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"34.4","Cell RNA - A549 [nTPM]":"59.6","Cell RNA - AF22 [nTPM]":"7.3","Cell RNA - AN3-CA [nTPM]":"9.3","Cell RNA - ASC diff [nTPM]":"4.3","Cell RNA - ASC TERT1 [nTPM]":"4.3","Cell RNA - BEWO [nTPM]":"4.9","Cell RNA - BJ [nTPM]":"14.5","Cell RNA - BJ hTERT+ [nTPM]":"12.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.8","Cell RNA - CACO-2 [nTPM]":"20.6","Cell RNA - CAPAN-2 [nTPM]":"19.5","Cell RNA - Daudi [nTPM]":"19.5","Cell RNA - EFO-21 [nTPM]":"12.2","Cell RNA - fHDF\/TERT166 [nTPM]":"12.4","Cell RNA - GAMG [nTPM]":"7.9","Cell RNA - HaCaT [nTPM]":"7.6","Cell RNA - HAP1 [nTPM]":"6.7","Cell RNA - HBEC3-KT [nTPM]":"27.1","Cell RNA - HBF TERT88 [nTPM]":"10.4","Cell RNA - HDLM-2 [nTPM]":"6.7","Cell RNA - HEK 293 [nTPM]":"3.3","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"5.5","Cell RNA - Hep G2 [nTPM]":"6.5","Cell RNA - HHSteC [nTPM]":"8.3","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"5.5","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"14.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.5","Cell RNA - hTERT-HME1 [nTPM]":"37.3","Cell RNA - hTERT-RPE1 [nTPM]":"13.9","Cell RNA - HUVEC TERT2 [nTPM]":"10.8","Cell RNA - JURKAT [nTPM]":"5.6","Cell RNA - K-562 [nTPM]":"3.9","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"16.6","Cell RNA - MCF7 [nTPM]":"10.6","Cell RNA - MOLT-4 [nTPM]":"5.0","Cell RNA - NB-4 [nTPM]":"5.1","Cell RNA - NTERA-2 [nTPM]":"6.0","Cell RNA - OE19 [nTPM]":"27.2","Cell RNA - PC-3 [nTPM]":"15.8","Cell RNA - REH [nTPM]":"10.8","Cell RNA - RH-30 [nTPM]":"5.9","Cell RNA - RPMI-8226 [nTPM]":"2.9","Cell RNA - RPTEC TERT1 [nTPM]":"20.7","Cell RNA - RT4 [nTPM]":"29.1","Cell RNA - SCLC-21H [nTPM]":"17.3","Cell RNA - SH-SY5Y [nTPM]":"9.3","Cell RNA - SiHa [nTPM]":"16.0","Cell RNA - SK-BR-3 [nTPM]":"27.1","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"18.0","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"23.2","Cell RNA - U-138 MG [nTPM]":"15.6","Cell RNA - U-2 OS [nTPM]":"5.5","Cell RNA - U-2197 [nTPM]":"48.4","Cell RNA - U-251 MG [nTPM]":"22.6","Cell RNA - U-266\/70 [nTPM]":"5.4","Cell RNA - U-266\/84 [nTPM]":"10.0","Cell RNA - U-698 [nTPM]":"6.6","Cell RNA - U-87 MG [nTPM]":"20.1","Cell RNA - U-937 [nTPM]":"4.9","Cell RNA - WM-115 [nTPM]":"20.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"6.0","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"16.2","Brain RNA - hippocampal formation [nTPM]":"28.9","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"3.5","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"5.6","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.1","Single Cell Type RNA - Astrocytes [nTPM]":"41.4","Single Cell Type RNA - B-cells [nTPM]":"24.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"21.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"9.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"93.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.8","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"23.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"87.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"5.1","Single Cell Type RNA - Langerhans cells [nTPM]":"13.9","Single Cell Type RNA - Late spermatids [nTPM]":"9.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"8.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"7.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.0","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"99.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"58.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.4","Single Cell Type RNA - Paneth cells [nTPM]":"38.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"12.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"5.1","Single Cell Type RNA - Theca cells [nTPM]":"1.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.4","Single Cell Type RNA - Urothelial cells [nTPM]":"5.6"},{"Gene":"SIX1","Gene synonym":["DFNA23"],"Ensembl":"ENSG00000126778","Gene description":"SIX homeobox 1","Uniprot":["Q15475"],"Chromosome":"14","Position":"60643421-60658259","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"47.8","salivary gland":"51.1","skeletal muscle":"119.4","tongue":"46.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"30.7","Basal respiratory cells":"30.8","Club cells":"33.9","Ionocytes":"30.5","Prostatic glandular cells":"27.4","Respiratory ciliated cells":"67.1","Skeletal myocytes":"77.3","Spermatogonia":"25.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-RPE1":"36.3","LHCN-M2":"142.2","RH-30":"71.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001893","CAB058690"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB058690":"AB_2665581","HPA001893":"AB_1079991"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.92e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.94e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.5","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"15.2","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"47.8","Tissue RNA - pituitary gland [nTPM]":"19.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"13.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"51.1","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"119.4","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"46.3","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"15.2","Cell RNA - A549 [nTPM]":"3.5","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"28.1","Cell RNA - ASC diff [nTPM]":"17.0","Cell RNA - ASC TERT1 [nTPM]":"20.6","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"4.1","Cell RNA - BJ hTERT+ [nTPM]":"10.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"8.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"2.1","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"10.3","Cell RNA - HBEC3-KT [nTPM]":"6.4","Cell RNA - HBF TERT88 [nTPM]":"2.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"17.1","Cell RNA - HEL [nTPM]":"2.0","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"6.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"15.6","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.3","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"36.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"5.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"142.2","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"8.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"71.9","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"16.3","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"5.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"6.1","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"3.3","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"13.9","Cell RNA - U-138 MG [nTPM]":"6.7","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"7.9","Cell RNA - U-251 MG [nTPM]":"6.5","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"33.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"67.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"77.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"25.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"18.3"},{"Gene":"SLC12A5","Gene synonym":["KCC2","KIAA1176"],"Ensembl":"ENSG00000124140","Gene description":"Solute carrier family 12 member 5","Uniprot":["Q9H2X9"],"Chromosome":"20","Position":"46021690-46060150","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"145.8","retina":"117.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"244.0","Cone photoreceptor cells":"383.7","Excitatory neurons":"92.7","Inhibitory neurons":"91.3","Rod photoreceptor cells":"170.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"2.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"24.9","NB-4":"50.8","SK-BR-3":"24.8","U-2 OS":"28.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072058"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA072058":"AB_2686485"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.60e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"26.7","Tissue RNA - amygdala [nTPM]":"101.3","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"103.5","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"97.6","Tissue RNA - cerebral cortex [nTPM]":"145.8","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"14.9","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"107.0","Tissue RNA - hypothalamus [nTPM]":"96.6","Tissue RNA - kidney [nTPM]":"1.1","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"2.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"76.3","Tissue RNA - midbrain [nTPM]":"80.5","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"1.8","Tissue RNA - pituitary gland [nTPM]":"41.5","Tissue RNA - placenta [nTPM]":"2.0","Tissue RNA - pons [nTPM]":"69.9","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"117.4","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"69.3","Tissue RNA - spleen [nTPM]":"3.0","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"86.7","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"88.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"15.2","Cell RNA - AF22 [nTPM]":"6.6","Cell RNA - AN3-CA [nTPM]":"4.9","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.5","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"2.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"5.8","Cell RNA - EFO-21 [nTPM]":"22.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"5.9","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"4.3","Cell RNA - HBEC3-KT [nTPM]":"2.3","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"3.7","Cell RNA - HEK 293 [nTPM]":"5.7","Cell RNA - HEL [nTPM]":"4.9","Cell RNA - HeLa [nTPM]":"3.0","Cell RNA - Hep G2 [nTPM]":"24.9","Cell RNA - HHSteC [nTPM]":"2.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"6.5","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"10.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"5.4","Cell RNA - K-562 [nTPM]":"9.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"23.1","Cell RNA - MOLT-4 [nTPM]":"3.5","Cell RNA - NB-4 [nTPM]":"50.8","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"5.8","Cell RNA - RH-30 [nTPM]":"4.2","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"8.1","Cell RNA - SH-SY5Y [nTPM]":"11.5","Cell RNA - SiHa [nTPM]":"2.9","Cell RNA - SK-BR-3 [nTPM]":"24.8","Cell RNA - SK-MEL-30 [nTPM]":"7.9","Cell RNA - SuSa [nTPM]":"6.0","Cell RNA - T-47d [nTPM]":"9.0","Cell RNA - THP-1 [nTPM]":"14.4","Cell RNA - TIME [nTPM]":"2.3","Cell RNA - U-138 MG [nTPM]":"2.7","Cell RNA - U-2 OS [nTPM]":"28.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"4.2","Cell RNA - U-698 [nTPM]":"8.2","Cell RNA - U-87 MG [nTPM]":"5.9","Cell RNA - U-937 [nTPM]":"5.9","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"101.3","Brain RNA - basal ganglia [nTPM]":"103.5","Brain RNA - cerebellum [nTPM]":"97.6","Brain RNA - cerebral cortex [nTPM]":"145.8","Brain RNA - hippocampal formation [nTPM]":"107.0","Brain RNA - hypothalamus [nTPM]":"96.6","Brain RNA - medulla oblongata [nTPM]":"76.3","Brain RNA - midbrain [nTPM]":"80.5","Brain RNA - pons [nTPM]":"69.9","Brain RNA - spinal cord [nTPM]":"69.3","Brain RNA - thalamus [nTPM]":"86.7","Brain RNA - white matter [nTPM]":"88.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"244.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"383.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.9","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"92.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"14.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.8","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"91.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"6.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"28.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"170.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"8.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SLC12A6","Gene synonym":["ACCPN","KCC3"],"Ensembl":"ENSG00000140199","Gene description":"Solute carrier family 12 member 6","Uniprot":["Q9UHW9"],"Chromosome":"15","Position":"34229784-34338060","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"85.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"15.2","neutrophil":"23.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"23.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"44.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034563"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA034563":"AB_10603887"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.4","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"26.8","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"11.9","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"5.5","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"5.2","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"18.8","Tissue RNA - fallopian tube [nTPM]":"4.6","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"7.3","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"15.9","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"9.1","Tissue RNA - lymph node [nTPM]":"10.1","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"4.2","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"9.3","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"31.1","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"10.6","Tissue RNA - skin 1 [nTPM]":"7.6","Tissue RNA - small intestine [nTPM]":"9.1","Tissue RNA - smooth muscle [nTPM]":"4.9","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"12.9","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"25.9","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"15.5","Tissue RNA - thyroid gland [nTPM]":"9.0","Tissue RNA - tongue [nTPM]":"10.9","Tissue RNA - tonsil [nTPM]":"11.6","Tissue RNA - urinary bladder [nTPM]":"8.3","Tissue RNA - vagina [nTPM]":"17.6","Tissue RNA - white matter [nTPM]":"8.4","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"4.7","Cell RNA - ASC diff [nTPM]":"10.0","Cell RNA - ASC TERT1 [nTPM]":"11.4","Cell RNA - BEWO [nTPM]":"2.4","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.1","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"7.2","Cell RNA - Daudi [nTPM]":"3.1","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"7.2","Cell RNA - GAMG [nTPM]":"4.3","Cell RNA - HaCaT [nTPM]":"44.0","Cell RNA - HAP1 [nTPM]":"7.9","Cell RNA - HBEC3-KT [nTPM]":"5.3","Cell RNA - HBF TERT88 [nTPM]":"5.8","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"5.1","Cell RNA - HEL [nTPM]":"24.6","Cell RNA - HeLa [nTPM]":"14.0","Cell RNA - Hep G2 [nTPM]":"7.0","Cell RNA - HHSteC [nTPM]":"6.4","Cell RNA - HL-60 [nTPM]":"14.5","Cell RNA - HMC-1 [nTPM]":"24.6","Cell RNA - HSkMC [nTPM]":"6.9","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.1","Cell RNA - hTERT-HME1 [nTPM]":"29.1","Cell RNA - hTERT-RPE1 [nTPM]":"10.9","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"6.8","Cell RNA - K-562 [nTPM]":"5.4","Cell RNA - Karpas-707 [nTPM]":"6.8","Cell RNA - LHCN-M2 [nTPM]":"6.7","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"11.0","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"3.8","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"7.1","Cell RNA - RH-30 [nTPM]":"5.5","Cell RNA - RPMI-8226 [nTPM]":"3.3","Cell RNA - RPTEC TERT1 [nTPM]":"5.5","Cell RNA - RT4 [nTPM]":"11.2","Cell RNA - SCLC-21H [nTPM]":"7.2","Cell RNA - SH-SY5Y [nTPM]":"5.0","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"1.5","Cell RNA - SuSa [nTPM]":"7.1","Cell RNA - T-47d [nTPM]":"2.8","Cell RNA - THP-1 [nTPM]":"4.8","Cell RNA - TIME [nTPM]":"9.4","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"21.0","Cell RNA - U-251 MG [nTPM]":"1.4","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"6.8","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"10.5","Cell RNA - WM-115 [nTPM]":"2.2","Blood RNA - basophil [nTPM]":"15.2","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"23.4","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"9.3","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"8.4","Single Cell Type RNA - Adipocytes [nTPM]":"16.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.0","Single Cell Type RNA - Astrocytes [nTPM]":"30.0","Single Cell Type RNA - B-cells [nTPM]":"32.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"4.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"85.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.2","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.6","Single Cell Type RNA - Early spermatids [nTPM]":"15.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"17.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"35.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.6","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.4","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"8.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"7.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"52.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"37.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.3","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"25.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"34.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.7","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"58.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.1","Single Cell Type RNA - Paneth cells [nTPM]":"9.7","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"29.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.0","Single Cell Type RNA - Spermatocytes [nTPM]":"39.9","Single Cell Type RNA - Spermatogonia [nTPM]":"21.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"18.0","Single Cell Type RNA - Theca cells [nTPM]":"4.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.4","Single Cell Type RNA - Urothelial cells [nTPM]":"43.6"},{"Gene":"SLC13A5","Gene synonym":["INDY","NACT"],"Ensembl":"ENSG00000141485","Gene description":"Solute carrier family 13 member 5","Uniprot":["Q86YT5"],"Chromosome":"17","Position":"6684719-6713377","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"liver":"414.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Hepatocytes":"381.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"liver cancer":"27.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"79","RNA cell line specific nTPM":{"Hep G2":"58.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044343"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA044343":"AB_10961771"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"2.7","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"7.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"7.9","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"414.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"38.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"58.0","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"7.0","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"7.9","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"4.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"24.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"381.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"23.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"7.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"SLC16A12","Gene synonym":["MCT12"],"Ensembl":"ENSG00000152779","Gene description":"Solute carrier family 16 member 12","Uniprot":["Q6ZSM3"],"Chromosome":"10","Position":"89430299-89556641","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"choroid plexus":"92.2","epididymis":"51.8","kidney":"85.2","pancreas":"25.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"18.1","Leydig cells":"27.1","Peritubular cells":"26.7","Proximal tubular cells":"69.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"renal cancer":"18.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"ASC TERT1":"23.0","HSkMC":"8.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037587"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA037587":"AB_2732475"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.50e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"9.2","Tissue RNA - choroid plexus [nTPM]":"92.2","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"51.8","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"4.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"4.9","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"85.2","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"2.5","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"25.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"14.1","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"6.2","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.2","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.2","Cell RNA - hTERT-HME1 [nTPM]":"1.5","Cell RNA - hTERT-RPE1 [nTPM]":"2.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"27.1","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"69.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"SLC17A8","Gene synonym":["DFNA25","VGLUT3"],"Ensembl":"ENSG00000179520","Gene description":"Solute carrier family 17 member 8","Uniprot":["Q8NDX2"],"Chromosome":"12","Position":"100357074-100422055","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Hearing","Ion transport","Neurotransmitter transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"11.3","intestine":"5.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"13.3","Proximal enterocytes":"43.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.5"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"11.3","midbrain":"8.3","pons":"6.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB079058"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079058":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"11.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"11.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC18A3","Gene synonym":["VACHT"],"Ensembl":"ENSG00000187714","Gene description":"Solute carrier family 18 member A3","Uniprot":["Q16572"],"Chromosome":"10","Position":"49610310-49612720","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"brain":"25.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Fibroblasts":"7.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"SH-SY5Y":"7.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"spinal cord":"78.1"},"Antibody":["CAB079011"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079011":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"19.7","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"18.9","Tissue RNA - midbrain [nTPM]":"8.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"25.6","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"19.7","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"18.9","Brain RNA - midbrain [nTPM]":"8.0","Brain RNA - pons [nTPM]":"25.6","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC19A2","Gene synonym":["THTR1","TRMA"],"Ensembl":"ENSG00000117479","Gene description":"Solute carrier family 19 member 2","Uniprot":["O60779"],"Chromosome":"1","Position":"169463909-169485944","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Deafness","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"124.1","tongue":"84.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"84.5","Syncytiotrophoblasts":"156.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006119","HPA016599"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA006119":"AB_1079996","HPA016599":"AB_1857005"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.41e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.70e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"42.2","Tissue RNA - adrenal gland [nTPM]":"17.8","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"8.3","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"8.7","Tissue RNA - breast [nTPM]":"20.9","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"10.5","Tissue RNA - choroid plexus [nTPM]":"9.3","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"3.5","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"21.3","Tissue RNA - gallbladder [nTPM]":"25.8","Tissue RNA - heart muscle [nTPM]":"31.2","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"13.0","Tissue RNA - liver [nTPM]":"37.1","Tissue RNA - lung [nTPM]":"19.5","Tissue RNA - lymph node [nTPM]":"2.6","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"20.5","Tissue RNA - pancreas [nTPM]":"22.2","Tissue RNA - parathyroid gland [nTPM]":"24.8","Tissue RNA - pituitary gland [nTPM]":"19.0","Tissue RNA - placenta [nTPM]":"18.1","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"10.5","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"12.5","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"124.1","Tissue RNA - skin 1 [nTPM]":"16.5","Tissue RNA - small intestine [nTPM]":"11.4","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"19.2","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"15.7","Tissue RNA - tongue [nTPM]":"84.9","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"7.4","Cell RNA - A549 [nTPM]":"5.1","Cell RNA - AF22 [nTPM]":"11.4","Cell RNA - AN3-CA [nTPM]":"9.0","Cell RNA - ASC diff [nTPM]":"34.4","Cell RNA - ASC TERT1 [nTPM]":"12.7","Cell RNA - BEWO [nTPM]":"25.0","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.5","Cell RNA - CACO-2 [nTPM]":"20.9","Cell RNA - CAPAN-2 [nTPM]":"7.6","Cell RNA - Daudi [nTPM]":"6.5","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"3.9","Cell RNA - GAMG [nTPM]":"8.5","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"13.9","Cell RNA - HBEC3-KT [nTPM]":"8.5","Cell RNA - HBF TERT88 [nTPM]":"5.1","Cell RNA - HDLM-2 [nTPM]":"18.8","Cell RNA - HEK 293 [nTPM]":"13.0","Cell RNA - HEL [nTPM]":"6.2","Cell RNA - HeLa [nTPM]":"16.7","Cell RNA - Hep G2 [nTPM]":"19.3","Cell RNA - HHSteC [nTPM]":"18.7","Cell RNA - HL-60 [nTPM]":"15.8","Cell RNA - HMC-1 [nTPM]":"5.9","Cell RNA - HSkMC [nTPM]":"15.0","Cell RNA - hTCEpi [nTPM]":"12.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.4","Cell RNA - hTERT-HME1 [nTPM]":"18.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.4","Cell RNA - HUVEC TERT2 [nTPM]":"7.0","Cell RNA - JURKAT [nTPM]":"11.3","Cell RNA - K-562 [nTPM]":"25.3","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"7.9","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"8.2","Cell RNA - NB-4 [nTPM]":"7.1","Cell RNA - NTERA-2 [nTPM]":"25.8","Cell RNA - OE19 [nTPM]":"14.1","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"24.6","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"12.2","Cell RNA - RT4 [nTPM]":"15.5","Cell RNA - SCLC-21H [nTPM]":"9.9","Cell RNA - SH-SY5Y [nTPM]":"13.3","Cell RNA - SiHa [nTPM]":"8.0","Cell RNA - SK-BR-3 [nTPM]":"13.6","Cell RNA - SK-MEL-30 [nTPM]":"29.2","Cell RNA - SuSa [nTPM]":"12.8","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"7.7","Cell RNA - U-2197 [nTPM]":"6.9","Cell RNA - U-251 MG [nTPM]":"11.4","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"5.6","Cell RNA - U-698 [nTPM]":"2.1","Cell RNA - U-87 MG [nTPM]":"8.1","Cell RNA - U-937 [nTPM]":"6.0","Cell RNA - WM-115 [nTPM]":"7.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"13.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.3","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"7.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"11.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.9","Single Cell Type RNA - dendritic cells [nTPM]":"11.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.7","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.5","Single Cell Type RNA - Fibroblasts [nTPM]":"52.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.7","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"4.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"29.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"8.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"18.3","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.6","Single Cell Type RNA - Paneth cells [nTPM]":"5.4","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"84.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.2","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"156.4","Single Cell Type RNA - T-cells [nTPM]":"7.5","Single Cell Type RNA - Theca cells [nTPM]":"3.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.7","Single Cell Type RNA - Urothelial cells [nTPM]":"28.9"},{"Gene":"SLC1A2","Gene synonym":["EAAT2","GLT-1"],"Ensembl":"ENSG00000110436","Gene description":"Solute carrier family 1 member 2","Uniprot":["P43004"],"Chromosome":"11","Position":"35251205-35420063","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"782.3","choroid plexus":"202.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"4607.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"28.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"2.1","BJ hTERT+":"2.4","fHDF\/TERT166":"1.7","Hep G2":"2.9","NTERA-2":"3.1","SCLC-21H":"1.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002574","HPA009172","HPA067499"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002574":"AB_564087","HPA009172":"AB_1849764","HPA067499":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"546.9","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"731.2","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"3.8","Tissue RNA - cerebellum [nTPM]":"388.1","Tissue RNA - cerebral cortex [nTPM]":"782.3","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"202.7","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"631.1","Tissue RNA - hypothalamus [nTPM]":"432.5","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"34.9","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"450.6","Tissue RNA - midbrain [nTPM]":"533.6","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"384.2","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"60.1","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"409.7","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"2.1","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"498.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"453.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"2.9","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"546.9","Brain RNA - basal ganglia [nTPM]":"731.2","Brain RNA - cerebellum [nTPM]":"388.1","Brain RNA - cerebral cortex [nTPM]":"782.3","Brain RNA - hippocampal formation [nTPM]":"631.1","Brain RNA - hypothalamus [nTPM]":"432.5","Brain RNA - medulla oblongata [nTPM]":"450.6","Brain RNA - midbrain [nTPM]":"533.6","Brain RNA - pons [nTPM]":"384.2","Brain RNA - spinal cord [nTPM]":"409.7","Brain RNA - thalamus [nTPM]":"498.7","Brain RNA - white matter [nTPM]":"453.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"4607.2","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"109.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"148.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"96.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"83.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"6.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.3","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"81.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"97.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"194.9","Single Cell Type RNA - monocytes [nTPM]":"31.6","Single Cell Type RNA - Muller glia cells [nTPM]":"10.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"634.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"161.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"269.4","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SLC1A3","Gene synonym":["EA6","EAAT1","GLAST"],"Ensembl":"ENSG00000079215","Gene description":"Solute carrier family 1 member 3","Uniprot":["P43003"],"Chromosome":"5","Position":"36596588-36688334","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"776.8","choroid plexus":"400.6","retina":"221.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1735.2","Microglial cells":"332.6","Muller glia cells":"472.6","Oligodendrocyte precursor cells":"237.7","Oligodendrocytes":"249.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"21","RNA cancer specific FPKM":{"glioma":"168.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"classical monocyte":"1.5","intermediate monocyte":"1.2","myeloid DC":"1.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"1.6","monocytes":"1.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"50.0","CACO-2":"112.6","HaCaT":"71.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002573","HPA037467","HPA037468"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoli","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002573":"AB_564088","HPA037467":"AB_10795027","HPA037468":"AB_10671371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"30.7","Tissue RNA - adrenal gland [nTPM]":"16.4","Tissue RNA - amygdala [nTPM]":"500.4","Tissue RNA - appendix [nTPM]":"7.4","Tissue RNA - basal ganglia [nTPM]":"544.2","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"17.7","Tissue RNA - cerebellum [nTPM]":"549.4","Tissue RNA - cerebral cortex [nTPM]":"776.8","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"400.6","Tissue RNA - colon [nTPM]":"3.0","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"10.5","Tissue RNA - fallopian tube [nTPM]":"6.0","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"45.4","Tissue RNA - hippocampal formation [nTPM]":"514.6","Tissue RNA - hypothalamus [nTPM]":"502.5","Tissue RNA - kidney [nTPM]":"2.2","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"10.2","Tissue RNA - lymph node [nTPM]":"17.4","Tissue RNA - medulla oblongata [nTPM]":"477.6","Tissue RNA - midbrain [nTPM]":"510.1","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"5.0","Tissue RNA - parathyroid gland [nTPM]":"2.2","Tissue RNA - pituitary gland [nTPM]":"18.1","Tissue RNA - placenta [nTPM]":"20.3","Tissue RNA - pons [nTPM]":"502.4","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"221.1","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"14.1","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"495.4","Tissue RNA - spleen [nTPM]":"9.3","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"532.8","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"9.2","Tissue RNA - tonsil [nTPM]":"5.4","Tissue RNA - urinary bladder [nTPM]":"7.0","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"494.9","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"50.0","Cell RNA - AN3-CA [nTPM]":"5.3","Cell RNA - ASC diff [nTPM]":"5.9","Cell RNA - ASC TERT1 [nTPM]":"14.3","Cell RNA - BEWO [nTPM]":"37.7","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.9","Cell RNA - CACO-2 [nTPM]":"112.6","Cell RNA - CAPAN-2 [nTPM]":"5.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"27.8","Cell RNA - fHDF\/TERT166 [nTPM]":"2.3","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"71.4","Cell RNA - HAP1 [nTPM]":"16.9","Cell RNA - HBEC3-KT [nTPM]":"9.1","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"1.8","Cell RNA - HEK 293 [nTPM]":"33.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"2.5","Cell RNA - HL-60 [nTPM]":"1.3","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"26.9","Cell RNA - hTCEpi [nTPM]":"34.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.4","Cell RNA - hTERT-HME1 [nTPM]":"5.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"8.7","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"6.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"3.1","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"5.1","Cell RNA - SK-BR-3 [nTPM]":"14.6","Cell RNA - SK-MEL-30 [nTPM]":"2.1","Cell RNA - SuSa [nTPM]":"24.4","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"3.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"6.2","Cell RNA - U-2 OS [nTPM]":"10.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"20.7","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"21.7","Cell RNA - U-937 [nTPM]":"37.7","Cell RNA - WM-115 [nTPM]":"12.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"500.4","Brain RNA - basal ganglia [nTPM]":"544.2","Brain RNA - cerebellum [nTPM]":"549.4","Brain RNA - cerebral cortex [nTPM]":"776.8","Brain RNA - hippocampal formation [nTPM]":"514.6","Brain RNA - hypothalamus [nTPM]":"502.5","Brain RNA - medulla oblongata [nTPM]":"477.6","Brain RNA - midbrain [nTPM]":"510.1","Brain RNA - pons [nTPM]":"502.4","Brain RNA - spinal cord [nTPM]":"495.4","Brain RNA - thalamus [nTPM]":"532.8","Brain RNA - white matter [nTPM]":"494.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1735.2","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"83.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"36.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"8.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.9","Single Cell Type RNA - Fibroblasts [nTPM]":"7.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"77.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"59.6","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"332.6","Single Cell Type RNA - monocytes [nTPM]":"3.3","Single Cell Type RNA - Muller glia cells [nTPM]":"472.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"237.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"249.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"20.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"SLC20A2","Gene synonym":["Glvr-2","GLVR2","MLVAR","PiT-2","Ram-1"],"Ensembl":"ENSG00000168575","Gene description":"Solute carrier family 20 member 2","Uniprot":["Q08357"],"Chromosome":"8","Position":"42416475-42541926","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Ion transport","Phosphate transport","Sodium transport","Symport","Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"130.6","skeletal muscle":"131.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"250.2","Oligodendrocytes":"151.7","Urothelial cells":"170.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"132.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026540"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026540":"AB_1855408"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.67e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"33.4","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"45.3","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"12.1","Tissue RNA - cerebellum [nTPM]":"55.4","Tissue RNA - cerebral cortex [nTPM]":"37.1","Tissue RNA - cervix [nTPM]":"15.8","Tissue RNA - choroid plexus [nTPM]":"130.6","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"46.7","Tissue RNA - endometrium 1 [nTPM]":"18.5","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"32.7","Tissue RNA - fallopian tube [nTPM]":"24.5","Tissue RNA - gallbladder [nTPM]":"15.1","Tissue RNA - heart muscle [nTPM]":"63.2","Tissue RNA - hippocampal formation [nTPM]":"30.1","Tissue RNA - hypothalamus [nTPM]":"48.7","Tissue RNA - kidney [nTPM]":"17.5","Tissue RNA - liver [nTPM]":"39.7","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"6.5","Tissue RNA - medulla oblongata [nTPM]":"46.5","Tissue RNA - midbrain [nTPM]":"56.5","Tissue RNA - ovary [nTPM]":"8.1","Tissue RNA - pancreas [nTPM]":"51.6","Tissue RNA - parathyroid gland [nTPM]":"15.0","Tissue RNA - pituitary gland [nTPM]":"10.5","Tissue RNA - placenta [nTPM]":"13.5","Tissue RNA - pons [nTPM]":"47.5","Tissue RNA - prostate [nTPM]":"13.6","Tissue RNA - rectum [nTPM]":"19.0","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"87.9","Tissue RNA - seminal vesicle [nTPM]":"17.6","Tissue RNA - skeletal muscle [nTPM]":"131.2","Tissue RNA - skin 1 [nTPM]":"23.3","Tissue RNA - small intestine [nTPM]":"18.8","Tissue RNA - smooth muscle [nTPM]":"17.9","Tissue RNA - spinal cord [nTPM]":"42.7","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"15.1","Tissue RNA - testis [nTPM]":"15.9","Tissue RNA - thalamus [nTPM]":"67.8","Tissue RNA - thymus [nTPM]":"11.9","Tissue RNA - thyroid gland [nTPM]":"82.8","Tissue RNA - tongue [nTPM]":"57.6","Tissue RNA - tonsil [nTPM]":"9.1","Tissue RNA - urinary bladder [nTPM]":"22.0","Tissue RNA - vagina [nTPM]":"21.7","Tissue RNA - white matter [nTPM]":"52.8","Cell RNA - A-431 [nTPM]":"52.7","Cell RNA - A549 [nTPM]":"14.3","Cell RNA - AF22 [nTPM]":"19.0","Cell RNA - AN3-CA [nTPM]":"16.0","Cell RNA - ASC diff [nTPM]":"10.4","Cell RNA - ASC TERT1 [nTPM]":"8.8","Cell RNA - BEWO [nTPM]":"41.1","Cell RNA - BJ [nTPM]":"46.9","Cell RNA - BJ hTERT+ [nTPM]":"80.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.7","Cell RNA - CACO-2 [nTPM]":"38.9","Cell RNA - CAPAN-2 [nTPM]":"132.9","Cell RNA - Daudi [nTPM]":"17.4","Cell RNA - EFO-21 [nTPM]":"53.6","Cell RNA - fHDF\/TERT166 [nTPM]":"42.1","Cell RNA - GAMG [nTPM]":"13.5","Cell RNA - HaCaT [nTPM]":"81.1","Cell RNA - HAP1 [nTPM]":"11.4","Cell RNA - HBEC3-KT [nTPM]":"45.2","Cell RNA - HBF TERT88 [nTPM]":"41.6","Cell RNA - HDLM-2 [nTPM]":"4.3","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"27.8","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"22.0","Cell RNA - HHSteC [nTPM]":"14.9","Cell RNA - HL-60 [nTPM]":"9.9","Cell RNA - HMC-1 [nTPM]":"12.3","Cell RNA - HSkMC [nTPM]":"9.5","Cell RNA - hTCEpi [nTPM]":"40.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.7","Cell RNA - hTERT-HME1 [nTPM]":"22.7","Cell RNA - hTERT-RPE1 [nTPM]":"16.7","Cell RNA - HUVEC TERT2 [nTPM]":"12.0","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"27.2","Cell RNA - Karpas-707 [nTPM]":"14.0","Cell RNA - LHCN-M2 [nTPM]":"47.3","Cell RNA - MCF7 [nTPM]":"14.4","Cell RNA - MOLT-4 [nTPM]":"18.1","Cell RNA - NB-4 [nTPM]":"16.1","Cell RNA - NTERA-2 [nTPM]":"19.2","Cell RNA - OE19 [nTPM]":"50.5","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"20.9","Cell RNA - RPMI-8226 [nTPM]":"18.5","Cell RNA - RPTEC TERT1 [nTPM]":"21.4","Cell RNA - RT4 [nTPM]":"47.5","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"19.2","Cell RNA - SiHa [nTPM]":"12.8","Cell RNA - SK-BR-3 [nTPM]":"21.8","Cell RNA - SK-MEL-30 [nTPM]":"12.8","Cell RNA - SuSa [nTPM]":"15.0","Cell RNA - T-47d [nTPM]":"17.5","Cell RNA - THP-1 [nTPM]":"17.3","Cell RNA - TIME [nTPM]":"34.9","Cell RNA - U-138 MG [nTPM]":"50.0","Cell RNA - U-2 OS [nTPM]":"17.4","Cell RNA - U-2197 [nTPM]":"12.3","Cell RNA - U-251 MG [nTPM]":"25.7","Cell RNA - U-266\/70 [nTPM]":"9.0","Cell RNA - U-266\/84 [nTPM]":"22.2","Cell RNA - U-698 [nTPM]":"12.6","Cell RNA - U-87 MG [nTPM]":"15.8","Cell RNA - U-937 [nTPM]":"19.5","Cell RNA - WM-115 [nTPM]":"28.3","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"4.3","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"4.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"4.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.7","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"6.8","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"33.4","Brain RNA - basal ganglia [nTPM]":"45.3","Brain RNA - cerebellum [nTPM]":"55.4","Brain RNA - cerebral cortex [nTPM]":"37.1","Brain RNA - hippocampal formation [nTPM]":"30.1","Brain RNA - hypothalamus [nTPM]":"48.7","Brain RNA - medulla oblongata [nTPM]":"46.5","Brain RNA - midbrain [nTPM]":"56.5","Brain RNA - pons [nTPM]":"47.5","Brain RNA - spinal cord [nTPM]":"42.7","Brain RNA - thalamus [nTPM]":"67.8","Brain RNA - white matter [nTPM]":"52.8","Single Cell Type RNA - Adipocytes [nTPM]":"11.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.6","Single Cell Type RNA - Astrocytes [nTPM]":"51.6","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"98.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"250.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"96.2","Single Cell Type RNA - Bipolar cells [nTPM]":"13.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"60.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"21.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.9","Single Cell Type RNA - dendritic cells [nTPM]":"14.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"76.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"29.6","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"79.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.8","Single Cell Type RNA - Endothelial cells [nTPM]":"18.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.2","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"17.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"30.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.2","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"88.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"12.2","Single Cell Type RNA - Late spermatids [nTPM]":"10.0","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"78.7","Single Cell Type RNA - monocytes [nTPM]":"7.3","Single Cell Type RNA - Muller glia cells [nTPM]":"14.4","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"63.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"151.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.4","Single Cell Type RNA - Paneth cells [nTPM]":"35.8","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"8.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"76.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"57.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.3","Single Cell Type RNA - Spermatocytes [nTPM]":"5.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"73.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"74.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.4","Single Cell Type RNA - T-cells [nTPM]":"14.2","Single Cell Type RNA - Theca cells [nTPM]":"23.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.5","Single Cell Type RNA - Urothelial cells [nTPM]":"170.3"},{"Gene":"SLC24A1","Gene synonym":["CSNB1D","HsT17412","KIAA0702","NCKX","NCKX1","RODX"],"Ensembl":"ENSG00000074621","Gene description":"Solute carrier family 24 member 1","Uniprot":["O60721"],"Chromosome":"15","Position":"65611366-65660995","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Sensory transduction","Symport","Transport","Vision"],"Molecular function":null,"Disease involvement":["Congenital stationary night blindness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"34","RNA tissue specific nTPM":{"retina":"193.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"338.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039370"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA039370":"AB_10960279"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.0","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"5.7","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"3.8","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"3.8","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"193.5","Tissue RNA - salivary gland [nTPM]":"2.6","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"3.0","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"3.2","Tissue RNA - white matter [nTPM]":"2.5","Cell RNA - A-431 [nTPM]":"1.5","Cell RNA - A549 [nTPM]":"3.0","Cell RNA - AF22 [nTPM]":"3.2","Cell RNA - AN3-CA [nTPM]":"2.9","Cell RNA - ASC diff [nTPM]":"4.7","Cell RNA - ASC TERT1 [nTPM]":"7.9","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.4","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"6.5","Cell RNA - Daudi [nTPM]":"2.1","Cell RNA - EFO-21 [nTPM]":"12.4","Cell RNA - fHDF\/TERT166 [nTPM]":"3.7","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"4.1","Cell RNA - HAP1 [nTPM]":"3.9","Cell RNA - HBEC3-KT [nTPM]":"4.2","Cell RNA - HBF TERT88 [nTPM]":"2.1","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"2.8","Cell RNA - HEL [nTPM]":"4.6","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"6.8","Cell RNA - HHSteC [nTPM]":"6.8","Cell RNA - HL-60 [nTPM]":"3.1","Cell RNA - HMC-1 [nTPM]":"6.0","Cell RNA - HSkMC [nTPM]":"6.7","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.1","Cell RNA - hTERT-HME1 [nTPM]":"12.3","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"6.4","Cell RNA - JURKAT [nTPM]":"4.8","Cell RNA - K-562 [nTPM]":"5.0","Cell RNA - Karpas-707 [nTPM]":"7.0","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"2.8","Cell RNA - NTERA-2 [nTPM]":"4.1","Cell RNA - OE19 [nTPM]":"13.5","Cell RNA - PC-3 [nTPM]":"1.2","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"5.6","Cell RNA - RT4 [nTPM]":"6.0","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"2.8","Cell RNA - SK-MEL-30 [nTPM]":"8.0","Cell RNA - SuSa [nTPM]":"4.4","Cell RNA - T-47d [nTPM]":"6.0","Cell RNA - THP-1 [nTPM]":"4.2","Cell RNA - TIME [nTPM]":"9.3","Cell RNA - U-138 MG [nTPM]":"3.7","Cell RNA - U-2 OS [nTPM]":"3.7","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"2.6","Cell RNA - U-266\/70 [nTPM]":"2.8","Cell RNA - U-266\/84 [nTPM]":"5.5","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"3.1","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"5.7","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"2.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"3.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"29.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"15.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.9","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"26.1","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"3.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"338.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.5","Single Cell Type RNA - Spermatocytes [nTPM]":"20.3","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"8.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"SLC25A1","Gene synonym":["CTP","SLC20A3"],"Ensembl":"ENSG00000100075","Gene description":"Solute carrier family 25 member 1","Uniprot":["P53007"],"Chromosome":"22","Position":"19175581-19178739","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"197.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"221.1","Proximal enterocytes":"304.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"101.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"113.3","Tissue RNA - adrenal gland [nTPM]":"76.3","Tissue RNA - amygdala [nTPM]":"45.8","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"46.9","Tissue RNA - bone marrow [nTPM]":"14.2","Tissue RNA - breast [nTPM]":"90.3","Tissue RNA - cerebellum [nTPM]":"49.5","Tissue RNA - cerebral cortex [nTPM]":"58.6","Tissue RNA - cervix [nTPM]":"43.5","Tissue RNA - choroid plexus [nTPM]":"47.6","Tissue RNA - colon [nTPM]":"63.9","Tissue RNA - duodenum [nTPM]":"114.1","Tissue RNA - endometrium 1 [nTPM]":"40.0","Tissue RNA - epididymis [nTPM]":"16.2","Tissue RNA - esophagus [nTPM]":"59.2","Tissue RNA - fallopian tube [nTPM]":"34.7","Tissue RNA - gallbladder [nTPM]":"21.5","Tissue RNA - heart muscle [nTPM]":"27.3","Tissue RNA - hippocampal formation [nTPM]":"41.5","Tissue RNA - hypothalamus [nTPM]":"65.8","Tissue RNA - kidney [nTPM]":"86.8","Tissue RNA - liver [nTPM]":"197.7","Tissue RNA - lung [nTPM]":"33.6","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"61.0","Tissue RNA - midbrain [nTPM]":"58.3","Tissue RNA - ovary [nTPM]":"43.6","Tissue RNA - pancreas [nTPM]":"54.8","Tissue RNA - parathyroid gland [nTPM]":"33.1","Tissue RNA - pituitary gland [nTPM]":"39.3","Tissue RNA - placenta [nTPM]":"27.4","Tissue RNA - pons [nTPM]":"73.0","Tissue RNA - prostate [nTPM]":"53.9","Tissue RNA - rectum [nTPM]":"33.9","Tissue RNA - retina [nTPM]":"5.6","Tissue RNA - salivary gland [nTPM]":"39.5","Tissue RNA - seminal vesicle [nTPM]":"30.0","Tissue RNA - skeletal muscle [nTPM]":"17.3","Tissue RNA - skin 1 [nTPM]":"49.1","Tissue RNA - small intestine [nTPM]":"92.4","Tissue RNA - smooth muscle [nTPM]":"21.0","Tissue RNA - spinal cord [nTPM]":"49.4","Tissue RNA - spleen [nTPM]":"31.4","Tissue RNA - stomach 1 [nTPM]":"52.9","Tissue RNA - testis [nTPM]":"36.3","Tissue RNA - thalamus [nTPM]":"51.8","Tissue RNA - thymus [nTPM]":"16.3","Tissue RNA - thyroid gland [nTPM]":"46.1","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"25.5","Tissue RNA - urinary bladder [nTPM]":"43.9","Tissue RNA - vagina [nTPM]":"40.8","Tissue RNA - white matter [nTPM]":"55.2","Cell RNA - A-431 [nTPM]":"111.9","Cell RNA - A549 [nTPM]":"114.3","Cell RNA - AF22 [nTPM]":"85.9","Cell RNA - AN3-CA [nTPM]":"73.6","Cell RNA - ASC diff [nTPM]":"209.1","Cell RNA - ASC TERT1 [nTPM]":"102.5","Cell RNA - BEWO [nTPM]":"91.2","Cell RNA - BJ [nTPM]":"77.5","Cell RNA - BJ hTERT+ [nTPM]":"96.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"90.4","Cell RNA - CACO-2 [nTPM]":"136.4","Cell RNA - CAPAN-2 [nTPM]":"77.2","Cell RNA - Daudi [nTPM]":"66.9","Cell RNA - EFO-21 [nTPM]":"38.8","Cell RNA - fHDF\/TERT166 [nTPM]":"110.5","Cell RNA - GAMG [nTPM]":"70.5","Cell RNA - HaCaT [nTPM]":"95.4","Cell RNA - HAP1 [nTPM]":"82.9","Cell RNA - HBEC3-KT [nTPM]":"138.1","Cell RNA - HBF TERT88 [nTPM]":"37.2","Cell RNA - HDLM-2 [nTPM]":"59.6","Cell RNA - HEK 293 [nTPM]":"164.1","Cell RNA - HEL [nTPM]":"35.5","Cell RNA - HeLa [nTPM]":"97.7","Cell RNA - Hep G2 [nTPM]":"278.4","Cell RNA - HHSteC [nTPM]":"148.2","Cell RNA - HL-60 [nTPM]":"67.3","Cell RNA - HMC-1 [nTPM]":"107.5","Cell RNA - HSkMC [nTPM]":"145.1","Cell RNA - hTCEpi [nTPM]":"81.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"75.7","Cell RNA - hTERT-HME1 [nTPM]":"58.4","Cell RNA - hTERT-RPE1 [nTPM]":"73.3","Cell RNA - HUVEC TERT2 [nTPM]":"62.8","Cell RNA - JURKAT [nTPM]":"53.4","Cell RNA - K-562 [nTPM]":"184.6","Cell RNA - Karpas-707 [nTPM]":"61.9","Cell RNA - LHCN-M2 [nTPM]":"74.7","Cell RNA - MCF7 [nTPM]":"288.1","Cell RNA - MOLT-4 [nTPM]":"37.0","Cell RNA - NB-4 [nTPM]":"80.8","Cell RNA - NTERA-2 [nTPM]":"57.5","Cell RNA - OE19 [nTPM]":"173.5","Cell RNA - PC-3 [nTPM]":"70.0","Cell RNA - REH [nTPM]":"70.4","Cell RNA - RH-30 [nTPM]":"44.6","Cell RNA - RPMI-8226 [nTPM]":"29.9","Cell RNA - RPTEC TERT1 [nTPM]":"196.2","Cell RNA - RT4 [nTPM]":"135.8","Cell RNA - SCLC-21H [nTPM]":"55.5","Cell RNA - SH-SY5Y [nTPM]":"71.2","Cell RNA - SiHa [nTPM]":"83.1","Cell RNA - SK-BR-3 [nTPM]":"163.0","Cell RNA - SK-MEL-30 [nTPM]":"48.6","Cell RNA - SuSa [nTPM]":"52.6","Cell RNA - T-47d [nTPM]":"122.6","Cell RNA - THP-1 [nTPM]":"171.7","Cell RNA - TIME [nTPM]":"63.6","Cell RNA - U-138 MG [nTPM]":"80.3","Cell RNA - U-2 OS [nTPM]":"69.3","Cell RNA - U-2197 [nTPM]":"62.0","Cell RNA - U-251 MG [nTPM]":"53.2","Cell RNA - U-266\/70 [nTPM]":"78.2","Cell RNA - U-266\/84 [nTPM]":"39.9","Cell RNA - U-698 [nTPM]":"35.4","Cell RNA - U-87 MG [nTPM]":"82.5","Cell RNA - U-937 [nTPM]":"31.5","Cell RNA - WM-115 [nTPM]":"41.4","Blood RNA - basophil [nTPM]":"11.6","Blood RNA - classical monocyte [nTPM]":"15.7","Blood RNA - eosinophil [nTPM]":"101.9","Blood RNA - gdT-cell [nTPM]":"16.6","Blood RNA - intermediate monocyte [nTPM]":"17.9","Blood RNA - MAIT T-cell [nTPM]":"10.6","Blood RNA - memory B-cell [nTPM]":"33.3","Blood RNA - memory CD4 T-cell [nTPM]":"18.7","Blood RNA - memory CD8 T-cell [nTPM]":"18.2","Blood RNA - myeloid DC [nTPM]":"13.7","Blood RNA - naive B-cell [nTPM]":"43.5","Blood RNA - naive CD4 T-cell [nTPM]":"16.7","Blood RNA - naive CD8 T-cell [nTPM]":"14.3","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"13.7","Blood RNA - non-classical monocyte [nTPM]":"23.8","Blood RNA - plasmacytoid DC [nTPM]":"10.5","Blood RNA - T-reg [nTPM]":"19.6","Blood RNA - total PBMC [nTPM]":"10.6","Brain RNA - amygdala [nTPM]":"45.8","Brain RNA - basal ganglia [nTPM]":"46.9","Brain RNA - cerebellum [nTPM]":"49.5","Brain RNA - cerebral cortex [nTPM]":"58.6","Brain RNA - hippocampal formation [nTPM]":"41.5","Brain RNA - hypothalamus [nTPM]":"65.8","Brain RNA - medulla oblongata [nTPM]":"61.0","Brain RNA - midbrain [nTPM]":"58.3","Brain RNA - pons [nTPM]":"73.0","Brain RNA - spinal cord [nTPM]":"49.4","Brain RNA - thalamus [nTPM]":"51.8","Brain RNA - white matter [nTPM]":"55.2","Single Cell Type RNA - Adipocytes [nTPM]":"18.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.9","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"35.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"7.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"44.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"17.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"135.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"178.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.5","Single Cell Type RNA - Early spermatids [nTPM]":"30.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.0","Single Cell Type RNA - Endothelial cells [nTPM]":"16.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.0","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"139.5","Single Cell Type RNA - Fibroblasts [nTPM]":"27.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"50.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"83.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"67.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"221.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"47.5","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"107.3","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"30.5","Single Cell Type RNA - Langerhans cells [nTPM]":"18.2","Single Cell Type RNA - Late spermatids [nTPM]":"98.8","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"32.6","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"29.6","Single Cell Type RNA - Muller glia cells [nTPM]":"27.7","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.7","Single Cell Type RNA - Paneth cells [nTPM]":"128.1","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"304.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"127.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.8","Single Cell Type RNA - Spermatocytes [nTPM]":"15.3","Single Cell Type RNA - Spermatogonia [nTPM]":"29.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"127.7","Single Cell Type RNA - T-cells [nTPM]":"24.6","Single Cell Type RNA - Theca cells [nTPM]":"55.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"108.3","Single Cell Type RNA - Urothelial cells [nTPM]":"30.4"},{"Gene":"SLC25A22","Gene synonym":["EIEE3","FLJ13044","GC1","NET44"],"Ensembl":"ENSG00000177542","Gene description":"Solute carrier family 25 member 22","Uniprot":["Q9H936"],"Chromosome":"11","Position":"790475-798281","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"83.1","pancreas":"83.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"143.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014662"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014662":"AB_10600808"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.8","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"49.1","Tissue RNA - appendix [nTPM]":"11.0","Tissue RNA - basal ganglia [nTPM]":"59.8","Tissue RNA - bone marrow [nTPM]":"7.5","Tissue RNA - breast [nTPM]":"11.2","Tissue RNA - cerebellum [nTPM]":"17.9","Tissue RNA - cerebral cortex [nTPM]":"83.1","Tissue RNA - cervix [nTPM]":"9.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"12.9","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"15.2","Tissue RNA - fallopian tube [nTPM]":"10.4","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"74.2","Tissue RNA - hypothalamus [nTPM]":"7.9","Tissue RNA - kidney [nTPM]":"15.1","Tissue RNA - liver [nTPM]":"40.2","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"10.1","Tissue RNA - medulla oblongata [nTPM]":"24.5","Tissue RNA - midbrain [nTPM]":"11.1","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"83.4","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"48.7","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"25.4","Tissue RNA - prostate [nTPM]":"13.9","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"16.1","Tissue RNA - salivary gland [nTPM]":"14.4","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"12.2","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"13.5","Tissue RNA - testis [nTPM]":"19.1","Tissue RNA - thalamus [nTPM]":"19.1","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"40.2","Cell RNA - A-431 [nTPM]":"56.2","Cell RNA - A549 [nTPM]":"35.7","Cell RNA - AF22 [nTPM]":"20.4","Cell RNA - AN3-CA [nTPM]":"18.6","Cell RNA - ASC diff [nTPM]":"8.3","Cell RNA - ASC TERT1 [nTPM]":"14.8","Cell RNA - BEWO [nTPM]":"19.4","Cell RNA - BJ [nTPM]":"26.3","Cell RNA - BJ hTERT+ [nTPM]":"21.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.7","Cell RNA - CACO-2 [nTPM]":"34.9","Cell RNA - CAPAN-2 [nTPM]":"37.1","Cell RNA - Daudi [nTPM]":"16.8","Cell RNA - EFO-21 [nTPM]":"19.2","Cell RNA - fHDF\/TERT166 [nTPM]":"21.6","Cell RNA - GAMG [nTPM]":"31.9","Cell RNA - HaCaT [nTPM]":"48.8","Cell RNA - HAP1 [nTPM]":"22.4","Cell RNA - HBEC3-KT [nTPM]":"31.1","Cell RNA - HBF TERT88 [nTPM]":"6.3","Cell RNA - HDLM-2 [nTPM]":"31.9","Cell RNA - HEK 293 [nTPM]":"41.4","Cell RNA - HEL [nTPM]":"15.4","Cell RNA - HeLa [nTPM]":"18.2","Cell RNA - Hep G2 [nTPM]":"21.9","Cell RNA - HHSteC [nTPM]":"35.8","Cell RNA - HL-60 [nTPM]":"24.7","Cell RNA - HMC-1 [nTPM]":"25.0","Cell RNA - HSkMC [nTPM]":"14.9","Cell RNA - hTCEpi [nTPM]":"18.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.4","Cell RNA - hTERT-HME1 [nTPM]":"22.6","Cell RNA - hTERT-RPE1 [nTPM]":"8.8","Cell RNA - HUVEC TERT2 [nTPM]":"13.0","Cell RNA - JURKAT [nTPM]":"19.3","Cell RNA - K-562 [nTPM]":"31.8","Cell RNA - Karpas-707 [nTPM]":"25.3","Cell RNA - LHCN-M2 [nTPM]":"12.7","Cell RNA - MCF7 [nTPM]":"33.9","Cell RNA - MOLT-4 [nTPM]":"26.3","Cell RNA - NB-4 [nTPM]":"23.5","Cell RNA - NTERA-2 [nTPM]":"44.8","Cell RNA - OE19 [nTPM]":"33.9","Cell RNA - PC-3 [nTPM]":"53.7","Cell RNA - REH [nTPM]":"30.9","Cell RNA - RH-30 [nTPM]":"11.2","Cell RNA - RPMI-8226 [nTPM]":"38.9","Cell RNA - RPTEC TERT1 [nTPM]":"16.8","Cell RNA - RT4 [nTPM]":"9.2","Cell RNA - SCLC-21H [nTPM]":"100.3","Cell RNA - SH-SY5Y [nTPM]":"45.3","Cell RNA - SiHa [nTPM]":"15.0","Cell RNA - SK-BR-3 [nTPM]":"35.9","Cell RNA - SK-MEL-30 [nTPM]":"18.7","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"17.4","Cell RNA - THP-1 [nTPM]":"12.5","Cell RNA - TIME [nTPM]":"13.0","Cell RNA - U-138 MG [nTPM]":"32.1","Cell RNA - U-2 OS [nTPM]":"21.5","Cell RNA - U-2197 [nTPM]":"14.8","Cell RNA - U-251 MG [nTPM]":"25.0","Cell RNA - U-266\/70 [nTPM]":"22.1","Cell RNA - U-266\/84 [nTPM]":"14.3","Cell RNA - U-698 [nTPM]":"21.5","Cell RNA - U-87 MG [nTPM]":"37.8","Cell RNA - U-937 [nTPM]":"22.2","Cell RNA - WM-115 [nTPM]":"19.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"3.4","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"49.1","Brain RNA - basal ganglia [nTPM]":"59.8","Brain RNA - cerebellum [nTPM]":"17.9","Brain RNA - cerebral cortex [nTPM]":"83.1","Brain RNA - hippocampal formation [nTPM]":"74.2","Brain RNA - hypothalamus [nTPM]":"7.9","Brain RNA - medulla oblongata [nTPM]":"24.5","Brain RNA - midbrain [nTPM]":"11.1","Brain RNA - pons [nTPM]":"25.4","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"19.1","Brain RNA - white matter [nTPM]":"40.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"8.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"143.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"22.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"17.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.3","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"7.7","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"4.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"6.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.0","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.1","Single Cell Type RNA - Paneth cells [nTPM]":"7.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"13.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - T-cells [nTPM]":"8.2","Single Cell Type RNA - Theca cells [nTPM]":"13.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.9","Single Cell Type RNA - Urothelial cells [nTPM]":"8.8"},{"Gene":"SLC25A4","Gene synonym":["ANT1","PEO2","PEO3","T1"],"Ensembl":"ENSG00000151729","Gene description":"Solute carrier family 25 member 4","Uniprot":["P12235"],"Chromosome":"4","Position":"185143266-185150382","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Host-virus interaction","Transport"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","FDA approved drug targets","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"heart muscle":"245.1","skeletal muscle":"190.8","tongue":"346.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"4722.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046835","HPA071684"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"380000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA046835":"AB_2679831","HPA071684":"AB_2686431"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.41e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"14.0","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"15.3","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"22.6","Tissue RNA - cerebral cortex [nTPM]":"30.6","Tissue RNA - cervix [nTPM]":"3.4","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"21.0","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"5.9","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"245.1","Tissue RNA - hippocampal formation [nTPM]":"16.7","Tissue RNA - hypothalamus [nTPM]":"11.8","Tissue RNA - kidney [nTPM]":"10.4","Tissue RNA - liver [nTPM]":"7.3","Tissue RNA - lung [nTPM]":"4.5","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"11.6","Tissue RNA - midbrain [nTPM]":"10.7","Tissue RNA - ovary [nTPM]":"4.9","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"7.8","Tissue RNA - pituitary gland [nTPM]":"9.5","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"11.8","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"19.9","Tissue RNA - salivary gland [nTPM]":"9.0","Tissue RNA - seminal vesicle [nTPM]":"12.6","Tissue RNA - skeletal muscle [nTPM]":"190.8","Tissue RNA - skin 1 [nTPM]":"3.3","Tissue RNA - small intestine [nTPM]":"6.8","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"9.4","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"15.7","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"346.6","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"18.2","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"3.1","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"5.1","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"4.6","Cell RNA - BJ [nTPM]":"2.6","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.0","Cell RNA - CACO-2 [nTPM]":"6.8","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"2.3","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"3.1","Cell RNA - GAMG [nTPM]":"2.4","Cell RNA - HaCaT [nTPM]":"2.5","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"2.7","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"3.9","Cell RNA - HEK 293 [nTPM]":"8.4","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"4.7","Cell RNA - Hep G2 [nTPM]":"8.1","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"1.5","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"6.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.7","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"2.3","Cell RNA - JURKAT [nTPM]":"4.0","Cell RNA - K-562 [nTPM]":"3.8","Cell RNA - Karpas-707 [nTPM]":"1.7","Cell RNA - LHCN-M2 [nTPM]":"1.9","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"3.1","Cell RNA - NTERA-2 [nTPM]":"4.1","Cell RNA - OE19 [nTPM]":"2.2","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"2.5","Cell RNA - RH-30 [nTPM]":"1.3","Cell RNA - RPMI-8226 [nTPM]":"3.2","Cell RNA - RPTEC TERT1 [nTPM]":"6.9","Cell RNA - RT4 [nTPM]":"4.8","Cell RNA - SCLC-21H [nTPM]":"8.1","Cell RNA - SH-SY5Y [nTPM]":"6.2","Cell RNA - SiHa [nTPM]":"3.1","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"12.5","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"2.4","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"1.7","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.4","Cell RNA - U-2197 [nTPM]":"1.5","Cell RNA - U-251 MG [nTPM]":"3.4","Cell RNA - U-266\/70 [nTPM]":"7.3","Cell RNA - U-266\/84 [nTPM]":"3.5","Cell RNA - U-698 [nTPM]":"2.9","Cell RNA - U-87 MG [nTPM]":"2.2","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"2.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"14.0","Brain RNA - basal ganglia [nTPM]":"15.3","Brain RNA - cerebellum [nTPM]":"22.6","Brain RNA - cerebral cortex [nTPM]":"30.6","Brain RNA - hippocampal formation [nTPM]":"16.7","Brain RNA - hypothalamus [nTPM]":"11.8","Brain RNA - medulla oblongata [nTPM]":"11.6","Brain RNA - midbrain [nTPM]":"10.7","Brain RNA - pons [nTPM]":"11.8","Brain RNA - spinal cord [nTPM]":"9.4","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"18.2","Single Cell Type RNA - Adipocytes [nTPM]":"37.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"76.4","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"37.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"159.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"119.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"180.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"53.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4722.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"115.8","Single Cell Type RNA - Club cells [nTPM]":"80.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"104.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"69.2","Single Cell Type RNA - dendritic cells [nTPM]":"41.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"988.0","Single Cell Type RNA - Ductal cells [nTPM]":"75.3","Single Cell Type RNA - Early spermatids [nTPM]":"20.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"77.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"80.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"53.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"74.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"56.5","Single Cell Type RNA - Fibroblasts [nTPM]":"120.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"54.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.6","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"18.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.5","Single Cell Type RNA - Hepatocytes [nTPM]":"92.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"65.9","Single Cell Type RNA - Horizontal cells [nTPM]":"159.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.6","Single Cell Type RNA - Ionocytes [nTPM]":"215.7","Single Cell Type RNA - Kupffer cells [nTPM]":"8.5","Single Cell Type RNA - Langerhans cells [nTPM]":"13.8","Single Cell Type RNA - Late spermatids [nTPM]":"16.7","Single Cell Type RNA - Leydig cells [nTPM]":"46.6","Single Cell Type RNA - Macrophages [nTPM]":"6.8","Single Cell Type RNA - Melanocytes [nTPM]":"190.3","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"9.0","Single Cell Type RNA - Muller glia cells [nTPM]":"541.2","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.4","Single Cell Type RNA - Paneth cells [nTPM]":"28.5","Single Cell Type RNA - Peritubular cells [nTPM]":"112.8","Single Cell Type RNA - Plasma cells [nTPM]":"76.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"59.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"113.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"178.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"144.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"221.0","Single Cell Type RNA - Sertoli cells [nTPM]":"105.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"134.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"402.7","Single Cell Type RNA - Spermatocytes [nTPM]":"28.0","Single Cell Type RNA - Spermatogonia [nTPM]":"34.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"40.5","Single Cell Type RNA - T-cells [nTPM]":"27.7","Single Cell Type RNA - Theca cells [nTPM]":"23.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.2","Single Cell Type RNA - Urothelial cells [nTPM]":"50.7"},{"Gene":"SLC25A46","Gene synonym":[],"Ensembl":"ENSG00000164209","Gene description":"Solute carrier family 25 member 46","Uniprot":["Q96AG3"],"Chromosome":"5","Position":"110738136-110765161","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"238.9","Late spermatids":"448.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039601","HPA071582"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA039601":"AB_2676592","HPA071582":"AB_2686422"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.41e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.9","Tissue RNA - adrenal gland [nTPM]":"15.9","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"19.9","Tissue RNA - basal ganglia [nTPM]":"11.8","Tissue RNA - bone marrow [nTPM]":"17.6","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"16.7","Tissue RNA - cervix [nTPM]":"18.5","Tissue RNA - choroid plexus [nTPM]":"7.8","Tissue RNA - colon [nTPM]":"22.1","Tissue RNA - duodenum [nTPM]":"23.8","Tissue RNA - endometrium 1 [nTPM]":"14.7","Tissue RNA - epididymis [nTPM]":"10.5","Tissue RNA - esophagus [nTPM]":"21.2","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"15.8","Tissue RNA - heart muscle [nTPM]":"31.1","Tissue RNA - hippocampal formation [nTPM]":"12.2","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"29.7","Tissue RNA - liver [nTPM]":"30.0","Tissue RNA - lung [nTPM]":"16.7","Tissue RNA - lymph node [nTPM]":"22.5","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"11.7","Tissue RNA - pancreas [nTPM]":"15.4","Tissue RNA - parathyroid gland [nTPM]":"20.6","Tissue RNA - pituitary gland [nTPM]":"4.9","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"15.7","Tissue RNA - rectum [nTPM]":"21.6","Tissue RNA - retina [nTPM]":"18.8","Tissue RNA - salivary gland [nTPM]":"13.3","Tissue RNA - seminal vesicle [nTPM]":"16.0","Tissue RNA - skeletal muscle [nTPM]":"55.8","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"20.8","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"15.7","Tissue RNA - stomach 1 [nTPM]":"20.1","Tissue RNA - testis [nTPM]":"21.9","Tissue RNA - thalamus [nTPM]":"11.2","Tissue RNA - thymus [nTPM]":"24.8","Tissue RNA - thyroid gland [nTPM]":"19.8","Tissue RNA - tongue [nTPM]":"60.2","Tissue RNA - tonsil [nTPM]":"26.8","Tissue RNA - urinary bladder [nTPM]":"19.0","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"14.1","Cell RNA - A-431 [nTPM]":"36.2","Cell RNA - A549 [nTPM]":"27.7","Cell RNA - AF22 [nTPM]":"25.7","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"65.2","Cell RNA - ASC TERT1 [nTPM]":"60.2","Cell RNA - BEWO [nTPM]":"9.9","Cell RNA - BJ [nTPM]":"44.3","Cell RNA - BJ hTERT+ [nTPM]":"55.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.3","Cell RNA - CACO-2 [nTPM]":"37.6","Cell RNA - CAPAN-2 [nTPM]":"28.7","Cell RNA - Daudi [nTPM]":"96.8","Cell RNA - EFO-21 [nTPM]":"44.8","Cell RNA - fHDF\/TERT166 [nTPM]":"50.1","Cell RNA - GAMG [nTPM]":"61.9","Cell RNA - HaCaT [nTPM]":"29.6","Cell RNA - HAP1 [nTPM]":"41.0","Cell RNA - HBEC3-KT [nTPM]":"71.2","Cell RNA - HBF TERT88 [nTPM]":"54.3","Cell RNA - HDLM-2 [nTPM]":"61.8","Cell RNA - HEK 293 [nTPM]":"20.8","Cell RNA - HEL [nTPM]":"40.1","Cell RNA - HeLa [nTPM]":"35.2","Cell RNA - Hep G2 [nTPM]":"25.6","Cell RNA - HHSteC [nTPM]":"53.1","Cell RNA - HL-60 [nTPM]":"37.3","Cell RNA - HMC-1 [nTPM]":"40.2","Cell RNA - HSkMC [nTPM]":"49.9","Cell RNA - hTCEpi [nTPM]":"25.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.5","Cell RNA - hTERT-HME1 [nTPM]":"39.6","Cell RNA - hTERT-RPE1 [nTPM]":"29.5","Cell RNA - HUVEC TERT2 [nTPM]":"31.9","Cell RNA - JURKAT [nTPM]":"37.2","Cell RNA - K-562 [nTPM]":"31.4","Cell RNA - Karpas-707 [nTPM]":"56.4","Cell RNA - LHCN-M2 [nTPM]":"54.1","Cell RNA - MCF7 [nTPM]":"27.3","Cell RNA - MOLT-4 [nTPM]":"54.0","Cell RNA - NB-4 [nTPM]":"17.2","Cell RNA - NTERA-2 [nTPM]":"18.1","Cell RNA - OE19 [nTPM]":"25.7","Cell RNA - PC-3 [nTPM]":"24.7","Cell RNA - REH [nTPM]":"26.0","Cell RNA - RH-30 [nTPM]":"57.0","Cell RNA - RPMI-8226 [nTPM]":"71.5","Cell RNA - RPTEC TERT1 [nTPM]":"35.1","Cell RNA - RT4 [nTPM]":"39.2","Cell RNA - SCLC-21H [nTPM]":"46.7","Cell RNA - SH-SY5Y [nTPM]":"33.5","Cell RNA - SiHa [nTPM]":"37.7","Cell RNA - SK-BR-3 [nTPM]":"29.7","Cell RNA - SK-MEL-30 [nTPM]":"49.7","Cell RNA - SuSa [nTPM]":"23.7","Cell RNA - T-47d [nTPM]":"30.9","Cell RNA - THP-1 [nTPM]":"35.3","Cell RNA - TIME [nTPM]":"42.5","Cell RNA - U-138 MG [nTPM]":"43.6","Cell RNA - U-2 OS [nTPM]":"21.0","Cell RNA - U-2197 [nTPM]":"40.7","Cell RNA - U-251 MG [nTPM]":"54.4","Cell RNA - U-266\/70 [nTPM]":"111.8","Cell RNA - U-266\/84 [nTPM]":"76.2","Cell RNA - U-698 [nTPM]":"68.4","Cell RNA - U-87 MG [nTPM]":"48.0","Cell RNA - U-937 [nTPM]":"43.8","Cell RNA - WM-115 [nTPM]":"24.0","Blood RNA - basophil [nTPM]":"29.2","Blood RNA - classical monocyte [nTPM]":"16.0","Blood RNA - eosinophil [nTPM]":"13.2","Blood RNA - gdT-cell [nTPM]":"12.3","Blood RNA - intermediate monocyte [nTPM]":"19.0","Blood RNA - MAIT T-cell [nTPM]":"12.5","Blood RNA - memory B-cell [nTPM]":"14.4","Blood RNA - memory CD4 T-cell [nTPM]":"13.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.9","Blood RNA - myeloid DC [nTPM]":"17.0","Blood RNA - naive B-cell [nTPM]":"14.5","Blood RNA - naive CD4 T-cell [nTPM]":"14.5","Blood RNA - naive CD8 T-cell [nTPM]":"14.8","Blood RNA - neutrophil [nTPM]":"6.6","Blood RNA - NK-cell [nTPM]":"20.9","Blood RNA - non-classical monocyte [nTPM]":"17.7","Blood RNA - plasmacytoid DC [nTPM]":"11.1","Blood RNA - T-reg [nTPM]":"18.2","Blood RNA - total PBMC [nTPM]":"17.4","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"11.8","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"16.7","Brain RNA - hippocampal formation [nTPM]":"12.2","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"11.2","Brain RNA - white matter [nTPM]":"14.1","Single Cell Type RNA - Adipocytes [nTPM]":"21.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.8","Single Cell Type RNA - Astrocytes [nTPM]":"40.8","Single Cell Type RNA - B-cells [nTPM]":"26.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"16.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"63.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"12.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.7","Single Cell Type RNA - dendritic cells [nTPM]":"18.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"18.1","Single Cell Type RNA - Early spermatids [nTPM]":"238.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.4","Single Cell Type RNA - Erythroid cells [nTPM]":"29.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"73.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.2","Single Cell Type RNA - Fibroblasts [nTPM]":"22.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"16.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"43.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"63.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.3","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"26.1","Single Cell Type RNA - Langerhans cells [nTPM]":"21.0","Single Cell Type RNA - Late spermatids [nTPM]":"448.2","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"23.9","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"28.1","Single Cell Type RNA - Muller glia cells [nTPM]":"21.9","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"91.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.9","Single Cell Type RNA - Paneth cells [nTPM]":"22.8","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"73.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"41.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.6","Single Cell Type RNA - Spermatocytes [nTPM]":"23.3","Single Cell Type RNA - Spermatogonia [nTPM]":"14.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.5","Single Cell Type RNA - T-cells [nTPM]":"23.9","Single Cell Type RNA - Theca cells [nTPM]":"22.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"SLC26A4","Gene synonym":["DFNB4","PDS"],"Ensembl":"ENSG00000091137","Gene description":"Solute carrier family 26 member 4","Uniprot":["O43511"],"Chromosome":"7","Position":"107660828-107717809","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"thyroid gland":"263.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"19.0","Excitatory neurons":"29.3","Inhibitory neurons":"53.9","Ionocytes":"54.9","Prostatic glandular cells":"17.3","Urothelial cells":"19.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"thyroid cancer":"37.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"88","RNA brain regional specific nTPM":{"amygdala":"4.0","basal ganglia":"10.2","cerebral cortex":"11.8","hippocampal formation":"8.8"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"naive B-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"1.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"1.6","hTERT-RPE1":"3.7","LHCN-M2":"2.1"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hippocampal formation":"9.7"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"4.8"},"Antibody":["HPA042860"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042860":"AB_10796680"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"10.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"11.8","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"8.8","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"3.8","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"263.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"10.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"11.8","Brain RNA - hippocampal formation [nTPM]":"8.8","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"19.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"19.9"},{"Gene":"SLC26A5","Gene synonym":["DFNB61","PRES"],"Ensembl":"ENSG00000170615","Gene description":"Solute carrier family 26 member 5","Uniprot":["P58743"],"Chromosome":"7","Position":"103352730-103446207","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell shape","Hearing"],"Molecular function":["Motor protein"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"6.4","Astrocytes":"5.5","Excitatory neurons":"4.1","Gastric mucus-secreting cells":"7.1","Hepatic stellate cells":"5.3","Inhibitory neurons":"3.5","Microglial cells":"6.5","Oligodendrocytes":"4.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"2.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"10.4"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"SLC2A1","Gene synonym":["CSE","DYT18","DYT9","GLUT","GLUT1","HTLVR"],"Ensembl":"ENSG00000117394","Gene description":"Solute carrier family 2 member 1","Uniprot":["P11166"],"Chromosome":"1","Position":"42925353-42958893","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Cataract","Disease variant","Dystonia","Epilepsy","Hereditary hemolytic anemia","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"98.7","skin 1":"79.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"833.8","Erythroid cells":"520.4","Extravillous trophoblasts":"536.4","Syncytiotrophoblasts":"2482.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"241.0","CACO-2":"219.9","Hep G2":"157.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002759","HPA031345","HPA058494"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002759":null,"HPA031345":"AB_2673835","HPA058494":"AB_2683734"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.65e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.39e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.55e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.05e-4"},"Tissue RNA - adipose tissue [nTPM]":"6.9","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"24.1","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"26.1","Tissue RNA - bone marrow [nTPM]":"41.6","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"33.7","Tissue RNA - cerebral cortex [nTPM]":"27.7","Tissue RNA - cervix [nTPM]":"28.6","Tissue RNA - choroid plexus [nTPM]":"43.6","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"5.1","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"54.1","Tissue RNA - fallopian tube [nTPM]":"8.2","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"10.0","Tissue RNA - hippocampal formation [nTPM]":"20.6","Tissue RNA - hypothalamus [nTPM]":"28.5","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"3.3","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"31.9","Tissue RNA - midbrain [nTPM]":"29.3","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"4.5","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"98.7","Tissue RNA - pons [nTPM]":"34.5","Tissue RNA - prostate [nTPM]":"6.0","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"24.6","Tissue RNA - salivary gland [nTPM]":"17.6","Tissue RNA - seminal vesicle [nTPM]":"5.1","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"79.8","Tissue RNA - small intestine [nTPM]":"4.6","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"24.7","Tissue RNA - spleen [nTPM]":"7.5","Tissue RNA - stomach 1 [nTPM]":"8.4","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"41.2","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"19.3","Tissue RNA - vagina [nTPM]":"54.2","Tissue RNA - white matter [nTPM]":"29.4","Cell RNA - A-431 [nTPM]":"60.5","Cell RNA - A549 [nTPM]":"52.9","Cell RNA - AF22 [nTPM]":"66.3","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"3.5","Cell RNA - ASC TERT1 [nTPM]":"1.2","Cell RNA - BEWO [nTPM]":"241.0","Cell RNA - BJ [nTPM]":"47.8","Cell RNA - BJ hTERT+ [nTPM]":"36.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.8","Cell RNA - CACO-2 [nTPM]":"219.9","Cell RNA - CAPAN-2 [nTPM]":"96.3","Cell RNA - Daudi [nTPM]":"22.2","Cell RNA - EFO-21 [nTPM]":"138.9","Cell RNA - fHDF\/TERT166 [nTPM]":"6.0","Cell RNA - GAMG [nTPM]":"26.5","Cell RNA - HaCaT [nTPM]":"43.6","Cell RNA - HAP1 [nTPM]":"12.5","Cell RNA - HBEC3-KT [nTPM]":"52.3","Cell RNA - HBF TERT88 [nTPM]":"14.8","Cell RNA - HDLM-2 [nTPM]":"16.4","Cell RNA - HEK 293 [nTPM]":"10.3","Cell RNA - HEL [nTPM]":"29.8","Cell RNA - HeLa [nTPM]":"20.9","Cell RNA - Hep G2 [nTPM]":"157.4","Cell RNA - HHSteC [nTPM]":"12.9","Cell RNA - HL-60 [nTPM]":"16.8","Cell RNA - HMC-1 [nTPM]":"8.1","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"21.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.3","Cell RNA - hTERT-HME1 [nTPM]":"20.5","Cell RNA - hTERT-RPE1 [nTPM]":"96.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"12.8","Cell RNA - K-562 [nTPM]":"81.2","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"11.7","Cell RNA - MCF7 [nTPM]":"46.6","Cell RNA - MOLT-4 [nTPM]":"7.4","Cell RNA - NB-4 [nTPM]":"11.7","Cell RNA - NTERA-2 [nTPM]":"35.1","Cell RNA - OE19 [nTPM]":"22.1","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"8.4","Cell RNA - RH-30 [nTPM]":"20.6","Cell RNA - RPMI-8226 [nTPM]":"23.3","Cell RNA - RPTEC TERT1 [nTPM]":"21.7","Cell RNA - RT4 [nTPM]":"17.9","Cell RNA - SCLC-21H [nTPM]":"27.0","Cell RNA - SH-SY5Y [nTPM]":"23.8","Cell RNA - SiHa [nTPM]":"47.7","Cell RNA - SK-BR-3 [nTPM]":"95.6","Cell RNA - SK-MEL-30 [nTPM]":"11.0","Cell RNA - SuSa [nTPM]":"70.0","Cell RNA - T-47d [nTPM]":"3.8","Cell RNA - THP-1 [nTPM]":"16.9","Cell RNA - TIME [nTPM]":"14.9","Cell RNA - U-138 MG [nTPM]":"25.6","Cell RNA - U-2 OS [nTPM]":"28.6","Cell RNA - U-2197 [nTPM]":"6.1","Cell RNA - U-251 MG [nTPM]":"83.8","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"6.5","Cell RNA - U-698 [nTPM]":"11.5","Cell RNA - U-87 MG [nTPM]":"57.1","Cell RNA - U-937 [nTPM]":"8.2","Cell RNA - WM-115 [nTPM]":"25.5","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"10.6","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"8.5","Blood RNA - memory B-cell [nTPM]":"10.9","Blood RNA - memory CD4 T-cell [nTPM]":"5.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.7","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"8.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"18.4","Blood RNA - T-reg [nTPM]":"6.2","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"24.1","Brain RNA - basal ganglia [nTPM]":"26.1","Brain RNA - cerebellum [nTPM]":"33.7","Brain RNA - cerebral cortex [nTPM]":"27.7","Brain RNA - hippocampal formation [nTPM]":"20.6","Brain RNA - hypothalamus [nTPM]":"28.5","Brain RNA - medulla oblongata [nTPM]":"31.9","Brain RNA - midbrain [nTPM]":"29.3","Brain RNA - pons [nTPM]":"34.5","Brain RNA - spinal cord [nTPM]":"24.7","Brain RNA - thalamus [nTPM]":"41.2","Brain RNA - white matter [nTPM]":"29.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"25.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"286.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"286.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"66.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"159.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"833.8","Single Cell Type RNA - dendritic cells [nTPM]":"33.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"53.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"112.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.0","Single Cell Type RNA - Endothelial cells [nTPM]":"100.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.4","Single Cell Type RNA - Erythroid cells [nTPM]":"520.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"536.4","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"118.9","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"6.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"84.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.4","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"34.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"5.0","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"71.2","Single Cell Type RNA - monocytes [nTPM]":"36.0","Single Cell Type RNA - Muller glia cells [nTPM]":"350.1","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"120.3","Single Cell Type RNA - Paneth cells [nTPM]":"51.9","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"11.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"118.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"99.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"238.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2482.5","Single Cell Type RNA - T-cells [nTPM]":"20.8","Single Cell Type RNA - Theca cells [nTPM]":"5.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.8","Single Cell Type RNA - Urothelial cells [nTPM]":"105.8"},{"Gene":"SLC33A1","Gene synonym":["ACATN","AT-1","AT1","SPG42"],"Ensembl":"ENSG00000169359","Gene description":"Solute carrier family 33 member 1","Uniprot":["O00400"],"Chromosome":"3","Position":"155821024-155854456","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Cataract","Deafness","Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042430"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042430":"AB_10806238"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"11.0","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"8.4","Tissue RNA - cerebellum [nTPM]":"4.6","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"7.2","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"12.9","Tissue RNA - esophagus [nTPM]":"8.0","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"10.4","Tissue RNA - liver [nTPM]":"17.2","Tissue RNA - lung [nTPM]":"8.4","Tissue RNA - lymph node [nTPM]":"5.0","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"30.9","Tissue RNA - parathyroid gland [nTPM]":"11.6","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"11.2","Tissue RNA - seminal vesicle [nTPM]":"11.0","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"5.8","Tissue RNA - stomach 1 [nTPM]":"8.8","Tissue RNA - testis [nTPM]":"5.4","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"18.8","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"6.8","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"18.9","Cell RNA - A549 [nTPM]":"17.7","Cell RNA - AF22 [nTPM]":"7.3","Cell RNA - AN3-CA [nTPM]":"8.3","Cell RNA - ASC diff [nTPM]":"24.4","Cell RNA - ASC TERT1 [nTPM]":"23.5","Cell RNA - BEWO [nTPM]":"12.9","Cell RNA - BJ [nTPM]":"13.1","Cell RNA - BJ hTERT+ [nTPM]":"21.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.7","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"22.0","Cell RNA - Daudi [nTPM]":"9.9","Cell RNA - EFO-21 [nTPM]":"24.1","Cell RNA - fHDF\/TERT166 [nTPM]":"13.1","Cell RNA - GAMG [nTPM]":"19.8","Cell RNA - HaCaT [nTPM]":"17.1","Cell RNA - HAP1 [nTPM]":"14.3","Cell RNA - HBEC3-KT [nTPM]":"15.2","Cell RNA - HBF TERT88 [nTPM]":"20.8","Cell RNA - HDLM-2 [nTPM]":"16.5","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"11.3","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"15.8","Cell RNA - HHSteC [nTPM]":"41.5","Cell RNA - HL-60 [nTPM]":"13.3","Cell RNA - HMC-1 [nTPM]":"8.9","Cell RNA - HSkMC [nTPM]":"18.4","Cell RNA - hTCEpi [nTPM]":"26.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.7","Cell RNA - hTERT-HME1 [nTPM]":"49.5","Cell RNA - hTERT-RPE1 [nTPM]":"20.5","Cell RNA - HUVEC TERT2 [nTPM]":"19.8","Cell RNA - JURKAT [nTPM]":"12.4","Cell RNA - K-562 [nTPM]":"8.6","Cell RNA - Karpas-707 [nTPM]":"27.8","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"14.3","Cell RNA - MOLT-4 [nTPM]":"5.0","Cell RNA - NB-4 [nTPM]":"3.7","Cell RNA - NTERA-2 [nTPM]":"6.8","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"14.9","Cell RNA - REH [nTPM]":"5.6","Cell RNA - RH-30 [nTPM]":"8.1","Cell RNA - RPMI-8226 [nTPM]":"29.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.7","Cell RNA - RT4 [nTPM]":"11.8","Cell RNA - SCLC-21H [nTPM]":"7.9","Cell RNA - SH-SY5Y [nTPM]":"5.9","Cell RNA - SiHa [nTPM]":"11.1","Cell RNA - SK-BR-3 [nTPM]":"24.5","Cell RNA - SK-MEL-30 [nTPM]":"21.4","Cell RNA - SuSa [nTPM]":"11.3","Cell RNA - T-47d [nTPM]":"8.1","Cell RNA - THP-1 [nTPM]":"11.2","Cell RNA - TIME [nTPM]":"21.4","Cell RNA - U-138 MG [nTPM]":"10.1","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"17.9","Cell RNA - U-251 MG [nTPM]":"13.1","Cell RNA - U-266\/70 [nTPM]":"33.2","Cell RNA - U-266\/84 [nTPM]":"14.4","Cell RNA - U-698 [nTPM]":"12.3","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"8.8","Cell RNA - WM-115 [nTPM]":"14.0","Blood RNA - basophil [nTPM]":"12.7","Blood RNA - classical monocyte [nTPM]":"8.4","Blood RNA - eosinophil [nTPM]":"6.2","Blood RNA - gdT-cell [nTPM]":"8.9","Blood RNA - intermediate monocyte [nTPM]":"6.3","Blood RNA - MAIT T-cell [nTPM]":"9.6","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"10.4","Blood RNA - naive B-cell [nTPM]":"3.5","Blood RNA - naive CD4 T-cell [nTPM]":"5.4","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"6.6","Blood RNA - non-classical monocyte [nTPM]":"6.5","Blood RNA - plasmacytoid DC [nTPM]":"16.1","Blood RNA - T-reg [nTPM]":"5.7","Blood RNA - total PBMC [nTPM]":"5.9","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"4.6","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"9.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"14.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"21.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.2","Single Cell Type RNA - dendritic cells [nTPM]":"21.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.3","Single Cell Type RNA - Early spermatids [nTPM]":"13.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.3","Single Cell Type RNA - Fibroblasts [nTPM]":"19.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.6","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"64.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.5","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.1","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.7","Single Cell Type RNA - Langerhans cells [nTPM]":"15.8","Single Cell Type RNA - Late spermatids [nTPM]":"13.2","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"15.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"19.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.4","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.4","Single Cell Type RNA - Paneth cells [nTPM]":"5.3","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"33.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.0","Single Cell Type RNA - Spermatocytes [nTPM]":"19.5","Single Cell Type RNA - Spermatogonia [nTPM]":"9.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.6","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"10.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.9","Single Cell Type RNA - Urothelial cells [nTPM]":"10.9"},{"Gene":"SLC35A2","Gene synonym":["UGALT","UGAT","UGT","UGT1","UGT2","UGTL"],"Ensembl":"ENSG00000102100","Gene description":"Solute carrier family 35 member A2","Uniprot":["P78381"],"Chromosome":"X","Position":"48903180-48911958","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036087"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA036087":"AB_10604093"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.16e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.64e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.23e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.8","Tissue RNA - adrenal gland [nTPM]":"20.5","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"14.3","Tissue RNA - bone marrow [nTPM]":"15.9","Tissue RNA - breast [nTPM]":"14.9","Tissue RNA - cerebellum [nTPM]":"14.3","Tissue RNA - cerebral cortex [nTPM]":"14.8","Tissue RNA - cervix [nTPM]":"18.7","Tissue RNA - choroid plexus [nTPM]":"19.4","Tissue RNA - colon [nTPM]":"29.3","Tissue RNA - duodenum [nTPM]":"17.3","Tissue RNA - endometrium 1 [nTPM]":"13.1","Tissue RNA - epididymis [nTPM]":"28.4","Tissue RNA - esophagus [nTPM]":"24.7","Tissue RNA - fallopian tube [nTPM]":"32.6","Tissue RNA - gallbladder [nTPM]":"15.2","Tissue RNA - heart muscle [nTPM]":"15.0","Tissue RNA - hippocampal formation [nTPM]":"14.5","Tissue RNA - hypothalamus [nTPM]":"15.8","Tissue RNA - kidney [nTPM]":"19.8","Tissue RNA - liver [nTPM]":"31.8","Tissue RNA - lung [nTPM]":"18.2","Tissue RNA - lymph node [nTPM]":"11.4","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"15.0","Tissue RNA - ovary [nTPM]":"9.3","Tissue RNA - pancreas [nTPM]":"30.0","Tissue RNA - parathyroid gland [nTPM]":"24.7","Tissue RNA - pituitary gland [nTPM]":"21.3","Tissue RNA - placenta [nTPM]":"19.9","Tissue RNA - pons [nTPM]":"15.4","Tissue RNA - prostate [nTPM]":"17.1","Tissue RNA - rectum [nTPM]":"28.2","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"23.8","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"14.0","Tissue RNA - skin 1 [nTPM]":"21.9","Tissue RNA - small intestine [nTPM]":"18.0","Tissue RNA - smooth muscle [nTPM]":"11.7","Tissue RNA - spinal cord [nTPM]":"14.4","Tissue RNA - spleen [nTPM]":"14.7","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"7.1","Tissue RNA - thalamus [nTPM]":"15.9","Tissue RNA - thymus [nTPM]":"11.8","Tissue RNA - thyroid gland [nTPM]":"15.4","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"14.7","Tissue RNA - urinary bladder [nTPM]":"19.8","Tissue RNA - vagina [nTPM]":"15.4","Tissue RNA - white matter [nTPM]":"15.9","Cell RNA - A-431 [nTPM]":"48.8","Cell RNA - A549 [nTPM]":"55.2","Cell RNA - AF22 [nTPM]":"18.8","Cell RNA - AN3-CA [nTPM]":"27.3","Cell RNA - ASC diff [nTPM]":"36.5","Cell RNA - ASC TERT1 [nTPM]":"31.6","Cell RNA - BEWO [nTPM]":"29.7","Cell RNA - BJ [nTPM]":"49.7","Cell RNA - BJ hTERT+ [nTPM]":"54.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.9","Cell RNA - CACO-2 [nTPM]":"64.0","Cell RNA - CAPAN-2 [nTPM]":"84.5","Cell RNA - Daudi [nTPM]":"18.8","Cell RNA - EFO-21 [nTPM]":"22.2","Cell RNA - fHDF\/TERT166 [nTPM]":"54.2","Cell RNA - GAMG [nTPM]":"64.4","Cell RNA - HaCaT [nTPM]":"67.0","Cell RNA - HAP1 [nTPM]":"51.7","Cell RNA - HBEC3-KT [nTPM]":"40.0","Cell RNA - HBF TERT88 [nTPM]":"39.7","Cell RNA - HDLM-2 [nTPM]":"27.9","Cell RNA - HEK 293 [nTPM]":"34.0","Cell RNA - HEL [nTPM]":"20.5","Cell RNA - HeLa [nTPM]":"33.1","Cell RNA - Hep G2 [nTPM]":"49.6","Cell RNA - HHSteC [nTPM]":"47.8","Cell RNA - HL-60 [nTPM]":"38.7","Cell RNA - HMC-1 [nTPM]":"40.9","Cell RNA - HSkMC [nTPM]":"35.7","Cell RNA - hTCEpi [nTPM]":"69.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.6","Cell RNA - hTERT-HME1 [nTPM]":"39.8","Cell RNA - hTERT-RPE1 [nTPM]":"28.9","Cell RNA - HUVEC TERT2 [nTPM]":"30.6","Cell RNA - JURKAT [nTPM]":"25.9","Cell RNA - K-562 [nTPM]":"38.7","Cell RNA - Karpas-707 [nTPM]":"29.8","Cell RNA - LHCN-M2 [nTPM]":"37.6","Cell RNA - MCF7 [nTPM]":"47.1","Cell RNA - MOLT-4 [nTPM]":"20.5","Cell RNA - NB-4 [nTPM]":"35.0","Cell RNA - NTERA-2 [nTPM]":"39.7","Cell RNA - OE19 [nTPM]":"55.3","Cell RNA - PC-3 [nTPM]":"67.7","Cell RNA - REH [nTPM]":"22.3","Cell RNA - RH-30 [nTPM]":"35.5","Cell RNA - RPMI-8226 [nTPM]":"61.1","Cell RNA - RPTEC TERT1 [nTPM]":"44.4","Cell RNA - RT4 [nTPM]":"39.1","Cell RNA - SCLC-21H [nTPM]":"21.8","Cell RNA - SH-SY5Y [nTPM]":"36.1","Cell RNA - SiHa [nTPM]":"52.9","Cell RNA - SK-BR-3 [nTPM]":"54.5","Cell RNA - SK-MEL-30 [nTPM]":"28.7","Cell RNA - SuSa [nTPM]":"35.1","Cell RNA - T-47d [nTPM]":"80.8","Cell RNA - THP-1 [nTPM]":"30.7","Cell RNA - TIME [nTPM]":"28.2","Cell RNA - U-138 MG [nTPM]":"30.3","Cell RNA - U-2 OS [nTPM]":"30.6","Cell RNA - U-2197 [nTPM]":"55.4","Cell RNA - U-251 MG [nTPM]":"27.5","Cell RNA - U-266\/70 [nTPM]":"45.1","Cell RNA - U-266\/84 [nTPM]":"32.8","Cell RNA - U-698 [nTPM]":"19.6","Cell RNA - U-87 MG [nTPM]":"38.4","Cell RNA - U-937 [nTPM]":"34.1","Cell RNA - WM-115 [nTPM]":"40.3","Blood RNA - basophil [nTPM]":"18.1","Blood RNA - classical monocyte [nTPM]":"22.3","Blood RNA - eosinophil [nTPM]":"40.0","Blood RNA - gdT-cell [nTPM]":"15.3","Blood RNA - intermediate monocyte [nTPM]":"23.4","Blood RNA - MAIT T-cell [nTPM]":"15.8","Blood RNA - memory B-cell [nTPM]":"10.7","Blood RNA - memory CD4 T-cell [nTPM]":"12.6","Blood RNA - memory CD8 T-cell [nTPM]":"13.9","Blood RNA - myeloid DC [nTPM]":"27.7","Blood RNA - naive B-cell [nTPM]":"9.9","Blood RNA - naive CD4 T-cell [nTPM]":"8.3","Blood RNA - naive CD8 T-cell [nTPM]":"14.6","Blood RNA - neutrophil [nTPM]":"24.2","Blood RNA - NK-cell [nTPM]":"13.8","Blood RNA - non-classical monocyte [nTPM]":"17.5","Blood RNA - plasmacytoid DC [nTPM]":"27.7","Blood RNA - T-reg [nTPM]":"13.1","Blood RNA - total PBMC [nTPM]":"11.9","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"14.3","Brain RNA - cerebellum [nTPM]":"14.3","Brain RNA - cerebral cortex [nTPM]":"14.8","Brain RNA - hippocampal formation [nTPM]":"14.5","Brain RNA - hypothalamus [nTPM]":"15.8","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"15.0","Brain RNA - pons [nTPM]":"15.4","Brain RNA - spinal cord [nTPM]":"14.4","Brain RNA - thalamus [nTPM]":"15.9","Brain RNA - white matter [nTPM]":"15.9","Single Cell Type RNA - Adipocytes [nTPM]":"16.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"13.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"23.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.0","Single Cell Type RNA - dendritic cells [nTPM]":"15.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"27.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.0","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.7","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.6","Single Cell Type RNA - Fibroblasts [nTPM]":"14.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"15.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.5","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"14.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"12.3","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"21.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.1","Single Cell Type RNA - Paneth cells [nTPM]":"19.7","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"19.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.4","Single Cell Type RNA - Spermatocytes [nTPM]":"10.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.0","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"12.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"23.4"},{"Gene":"SLC38A8","Gene synonym":[],"Ensembl":"ENSG00000166558","Gene description":"Solute carrier family 38 member 8","Uniprot":["A6NNN8"],"Chromosome":"16","Position":"84009667-84042795","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"3.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"16.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"melanoma":"6.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"2.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"16.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC39A5","Gene synonym":[],"Ensembl":"ENSG00000139540","Gene description":"Solute carrier family 39 member 5","Uniprot":["Q6ZMH5"],"Chromosome":"12","Position":"56230049-56237846","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"intestine":"237.4","kidney":"110.0","liver":"171.1","pancreas":"306.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"798.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"30.6","liver cancer":"36.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"53","RNA cell line specific nTPM":{"CACO-2":"39.9","Hep G2":"58.5"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.1"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018423"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA018423":"AB_1857154"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"73.7","Tissue RNA - duodenum [nTPM]":"237.4","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"110.0","Tissue RNA - liver [nTPM]":"171.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"306.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"45.9","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"219.0","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"39.9","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"58.5","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"116.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"171.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.3","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"138.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"112.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.4","Single Cell Type RNA - Paneth cells [nTPM]":"192.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"798.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"169.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"168.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC44A4","Gene synonym":["C6orf29","CTL4","DFNA72","FLJ14491","NG22","TPPT"],"Ensembl":"ENSG00000204385","Gene description":"Solute carrier family 44 member 4","Uniprot":["Q53GD3"],"Chromosome":"6","Position":"31863192-31879046","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"132.0","prostate":"83.0","stomach 1":"83.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"546.0","Exocrine glandular cells":"213.4","Intestinal goblet cells":"327.8","Paneth cells":"299.3","Proximal enterocytes":"267.7","Respiratory ciliated cells":"406.7","Undifferentiated cells":"259.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"222.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"OE19":"14.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046977","HPA054176"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046977":"AB_2679887","HPA054176":"AB_2682404"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.54e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.06e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"8.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"22.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"132.0","Tissue RNA - duodenum [nTPM]":"100.8","Tissue RNA - endometrium 1 [nTPM]":"5.9","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"46.9","Tissue RNA - gallbladder [nTPM]":"18.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"32.1","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"14.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"16.1","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"83.0","Tissue RNA - rectum [nTPM]":"30.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"42.6","Tissue RNA - seminal vesicle [nTPM]":"3.9","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"86.8","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"83.4","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"11.0","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"14.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"71.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"180.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"66.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"546.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"111.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"127.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"213.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"208.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"67.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"327.8","Single Cell Type RNA - Ionocytes [nTPM]":"91.6","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"184.0","Single Cell Type RNA - Paneth cells [nTPM]":"299.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"142.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"267.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"61.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"406.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"5.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"259.6","Single Cell Type RNA - Urothelial cells [nTPM]":"139.4"},{"Gene":"SLC4A11","Gene synonym":["BTR1","CDPD1","CHED2","dJ794I6.2","FECD4","NaBC1"],"Ensembl":"ENSG00000088836","Gene description":"Solute carrier family 4 member 11","Uniprot":["Q8NBS3"],"Chromosome":"20","Position":"3227417-3239559","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Ion transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Corneal dystrophy","Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"51.3","salivary gland":"54.0","thyroid gland":"60.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"25.5","Collecting duct cells":"112.2","Ionocytes":"79.3","Respiratory ciliated cells":"48.1","Sertoli cells":"26.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"70.6","Hep G2":"43.0","RT4":"30.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018120","HPA058377"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA018120":"AB_1857186","HPA058377":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.03e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.4","Tissue RNA - adrenal gland [nTPM]":"6.9","Tissue RNA - amygdala [nTPM]":"4.5","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"10.9","Tissue RNA - choroid plexus [nTPM]":"5.6","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"51.3","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"54.0","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"12.8","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"60.9","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"3.4","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"11.0","Cell RNA - A549 [nTPM]":"15.5","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"7.9","Cell RNA - ASC diff [nTPM]":"5.1","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"21.1","Cell RNA - BJ [nTPM]":"5.4","Cell RNA - BJ hTERT+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"6.6","Cell RNA - HaCaT [nTPM]":"70.6","Cell RNA - HAP1 [nTPM]":"8.3","Cell RNA - HBEC3-KT [nTPM]":"16.8","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"3.2","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"7.5","Cell RNA - Hep G2 [nTPM]":"43.0","Cell RNA - HHSteC [nTPM]":"3.2","Cell RNA - HL-60 [nTPM]":"4.0","Cell RNA - HMC-1 [nTPM]":"13.6","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"6.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.4","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"2.3","Cell RNA - HUVEC TERT2 [nTPM]":"7.0","Cell RNA - JURKAT [nTPM]":"9.8","Cell RNA - K-562 [nTPM]":"1.6","Cell RNA - Karpas-707 [nTPM]":"9.7","Cell RNA - LHCN-M2 [nTPM]":"2.9","Cell RNA - MCF7 [nTPM]":"7.2","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"12.1","Cell RNA - OE19 [nTPM]":"13.6","Cell RNA - PC-3 [nTPM]":"20.7","Cell RNA - REH [nTPM]":"2.6","Cell RNA - RH-30 [nTPM]":"10.3","Cell RNA - RPMI-8226 [nTPM]":"3.5","Cell RNA - RPTEC TERT1 [nTPM]":"16.9","Cell RNA - RT4 [nTPM]":"30.7","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"17.5","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"5.4","Cell RNA - T-47d [nTPM]":"6.7","Cell RNA - THP-1 [nTPM]":"7.0","Cell RNA - TIME [nTPM]":"12.1","Cell RNA - U-138 MG [nTPM]":"2.1","Cell RNA - U-2 OS [nTPM]":"7.0","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"2.8","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.5","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"25.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"112.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"5.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"79.3","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"48.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"5.7"},{"Gene":"SLC52A2","Gene synonym":["D15Ertd747e","FLJ11856","GPCR41","GPR172A","hRFT3","PAR1","RFVT2"],"Ensembl":"ENSG00000185803","Gene description":"Solute carrier family 52 member 2","Uniprot":["Q9HAB3"],"Chromosome":"8","Position":"144333957-144361286","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Deafness","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"149.0","PC-3":"167.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063036"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063036":"AB_2684928"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.55e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"29.7","Tissue RNA - adrenal gland [nTPM]":"31.6","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"13.4","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"27.8","Tissue RNA - cerebellum [nTPM]":"15.3","Tissue RNA - cerebral cortex [nTPM]":"18.5","Tissue RNA - cervix [nTPM]":"21.7","Tissue RNA - choroid plexus [nTPM]":"14.5","Tissue RNA - colon [nTPM]":"35.7","Tissue RNA - duodenum [nTPM]":"9.4","Tissue RNA - endometrium 1 [nTPM]":"23.0","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"33.3","Tissue RNA - fallopian tube [nTPM]":"17.3","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"26.4","Tissue RNA - hippocampal formation [nTPM]":"13.5","Tissue RNA - hypothalamus [nTPM]":"14.5","Tissue RNA - kidney [nTPM]":"29.2","Tissue RNA - liver [nTPM]":"16.9","Tissue RNA - lung [nTPM]":"24.6","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"15.0","Tissue RNA - midbrain [nTPM]":"14.9","Tissue RNA - ovary [nTPM]":"15.6","Tissue RNA - pancreas [nTPM]":"41.6","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"24.5","Tissue RNA - placenta [nTPM]":"7.7","Tissue RNA - pons [nTPM]":"14.6","Tissue RNA - prostate [nTPM]":"22.2","Tissue RNA - rectum [nTPM]":"5.7","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"29.8","Tissue RNA - seminal vesicle [nTPM]":"6.3","Tissue RNA - skeletal muscle [nTPM]":"13.5","Tissue RNA - skin 1 [nTPM]":"30.4","Tissue RNA - small intestine [nTPM]":"29.6","Tissue RNA - smooth muscle [nTPM]":"4.3","Tissue RNA - spinal cord [nTPM]":"14.0","Tissue RNA - spleen [nTPM]":"34.8","Tissue RNA - stomach 1 [nTPM]":"31.4","Tissue RNA - testis [nTPM]":"31.5","Tissue RNA - thalamus [nTPM]":"15.1","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"21.7","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"24.9","Tissue RNA - vagina [nTPM]":"21.2","Tissue RNA - white matter [nTPM]":"14.1","Cell RNA - A-431 [nTPM]":"38.7","Cell RNA - A549 [nTPM]":"65.0","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"17.9","Cell RNA - ASC diff [nTPM]":"19.3","Cell RNA - ASC TERT1 [nTPM]":"12.3","Cell RNA - BEWO [nTPM]":"37.3","Cell RNA - BJ [nTPM]":"28.1","Cell RNA - BJ hTERT+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.6","Cell RNA - CACO-2 [nTPM]":"57.9","Cell RNA - CAPAN-2 [nTPM]":"42.3","Cell RNA - Daudi [nTPM]":"16.3","Cell RNA - EFO-21 [nTPM]":"42.3","Cell RNA - fHDF\/TERT166 [nTPM]":"27.5","Cell RNA - GAMG [nTPM]":"20.7","Cell RNA - HaCaT [nTPM]":"42.6","Cell RNA - HAP1 [nTPM]":"18.4","Cell RNA - HBEC3-KT [nTPM]":"25.3","Cell RNA - HBF TERT88 [nTPM]":"9.8","Cell RNA - HDLM-2 [nTPM]":"18.3","Cell RNA - HEK 293 [nTPM]":"34.5","Cell RNA - HEL [nTPM]":"26.3","Cell RNA - HeLa [nTPM]":"31.3","Cell RNA - Hep G2 [nTPM]":"50.1","Cell RNA - HHSteC [nTPM]":"51.7","Cell RNA - HL-60 [nTPM]":"9.4","Cell RNA - HMC-1 [nTPM]":"29.4","Cell RNA - HSkMC [nTPM]":"14.8","Cell RNA - hTCEpi [nTPM]":"34.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.4","Cell RNA - hTERT-HME1 [nTPM]":"24.4","Cell RNA - hTERT-RPE1 [nTPM]":"19.2","Cell RNA - HUVEC TERT2 [nTPM]":"15.8","Cell RNA - JURKAT [nTPM]":"16.2","Cell RNA - K-562 [nTPM]":"40.9","Cell RNA - Karpas-707 [nTPM]":"23.7","Cell RNA - LHCN-M2 [nTPM]":"18.7","Cell RNA - MCF7 [nTPM]":"149.0","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"38.0","Cell RNA - NTERA-2 [nTPM]":"17.9","Cell RNA - OE19 [nTPM]":"51.5","Cell RNA - PC-3 [nTPM]":"167.6","Cell RNA - REH [nTPM]":"29.8","Cell RNA - RH-30 [nTPM]":"8.9","Cell RNA - RPMI-8226 [nTPM]":"44.9","Cell RNA - RPTEC TERT1 [nTPM]":"30.6","Cell RNA - RT4 [nTPM]":"34.4","Cell RNA - SCLC-21H [nTPM]":"25.9","Cell RNA - SH-SY5Y [nTPM]":"29.4","Cell RNA - SiHa [nTPM]":"31.1","Cell RNA - SK-BR-3 [nTPM]":"44.1","Cell RNA - SK-MEL-30 [nTPM]":"35.7","Cell RNA - SuSa [nTPM]":"9.9","Cell RNA - T-47d [nTPM]":"27.8","Cell RNA - THP-1 [nTPM]":"18.7","Cell RNA - TIME [nTPM]":"20.2","Cell RNA - U-138 MG [nTPM]":"20.9","Cell RNA - U-2 OS [nTPM]":"46.9","Cell RNA - U-2197 [nTPM]":"48.2","Cell RNA - U-251 MG [nTPM]":"37.9","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"13.8","Cell RNA - U-698 [nTPM]":"12.4","Cell RNA - U-87 MG [nTPM]":"37.8","Cell RNA - U-937 [nTPM]":"26.6","Cell RNA - WM-115 [nTPM]":"25.7","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"4.2","Blood RNA - eosinophil [nTPM]":"9.2","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"5.9","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"3.3","Blood RNA - memory CD4 T-cell [nTPM]":"3.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.6","Blood RNA - myeloid DC [nTPM]":"4.5","Blood RNA - naive B-cell [nTPM]":"9.8","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"5.2","Blood RNA - non-classical monocyte [nTPM]":"7.5","Blood RNA - plasmacytoid DC [nTPM]":"7.6","Blood RNA - T-reg [nTPM]":"5.7","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"13.4","Brain RNA - cerebellum [nTPM]":"15.3","Brain RNA - cerebral cortex [nTPM]":"18.5","Brain RNA - hippocampal formation [nTPM]":"13.5","Brain RNA - hypothalamus [nTPM]":"14.5","Brain RNA - medulla oblongata [nTPM]":"15.0","Brain RNA - midbrain [nTPM]":"14.9","Brain RNA - pons [nTPM]":"14.6","Brain RNA - spinal cord [nTPM]":"14.0","Brain RNA - thalamus [nTPM]":"15.1","Brain RNA - white matter [nTPM]":"14.1","Single Cell Type RNA - Adipocytes [nTPM]":"31.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.7","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"24.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"41.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"11.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"34.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"85.0","Single Cell Type RNA - dendritic cells [nTPM]":"36.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"81.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"62.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.6","Single Cell Type RNA - Endothelial cells [nTPM]":"24.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.4","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"66.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"92.1","Single Cell Type RNA - Fibroblasts [nTPM]":"22.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.5","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"16.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"5.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"52.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"56.3","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"13.5","Single Cell Type RNA - Langerhans cells [nTPM]":"27.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.8","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"21.4","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"40.7","Single Cell Type RNA - Muller glia cells [nTPM]":"14.3","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"85.1","Single Cell Type RNA - Paneth cells [nTPM]":"46.7","Single Cell Type RNA - Peritubular cells [nTPM]":"19.9","Single Cell Type RNA - Plasma cells [nTPM]":"43.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"54.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"52.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.1","Single Cell Type RNA - Spermatocytes [nTPM]":"34.0","Single Cell Type RNA - Spermatogonia [nTPM]":"40.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.5","Single Cell Type RNA - T-cells [nTPM]":"24.8","Single Cell Type RNA - Theca cells [nTPM]":"23.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"65.6","Single Cell Type RNA - Urothelial cells [nTPM]":"36.7"},{"Gene":"SLC52A3","Gene synonym":["bA371L19.1","C20orf54","hRFT2","RFVT3"],"Ensembl":"ENSG00000101276","Gene description":"Solute carrier family 52 member 3","Uniprot":["Q9NQ40"],"Chromosome":"20","Position":"760080-776015","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"19.2","testis":"40.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"23.9","Cytotrophoblasts":"32.8","Distal enterocytes":"18.8","Glandular and luminal cells":"21.3","Paneth cells":"21.7","Proximal enterocytes":"35.5","Syncytiotrophoblasts":"52.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"42.1","OE19":"31.8","RT4":"12.3","SK-BR-3":"15.4","T-47d":"20.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049391","HPA059078"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049391":"AB_2680743","HPA059078":"AB_2732630"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.51e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"8.9","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"2.6","Tissue RNA - cerebellum [nTPM]":"9.5","Tissue RNA - cerebral cortex [nTPM]":"11.4","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"11.5","Tissue RNA - duodenum [nTPM]":"14.4","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"5.7","Tissue RNA - hippocampal formation [nTPM]":"9.0","Tissue RNA - hypothalamus [nTPM]":"11.1","Tissue RNA - kidney [nTPM]":"9.4","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"12.9","Tissue RNA - midbrain [nTPM]":"9.8","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"19.2","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"9.8","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"5.6","Tissue RNA - testis [nTPM]":"40.1","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"6.6","Cell RNA - A549 [nTPM]":"2.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"42.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"7.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"6.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"6.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"31.8","Cell RNA - PC-3 [nTPM]":"4.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"12.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"7.2","Cell RNA - SK-BR-3 [nTPM]":"15.4","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"20.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"8.9","Brain RNA - cerebellum [nTPM]":"9.5","Brain RNA - cerebral cortex [nTPM]":"11.4","Brain RNA - hippocampal formation [nTPM]":"9.0","Brain RNA - hypothalamus [nTPM]":"11.1","Brain RNA - medulla oblongata [nTPM]":"12.9","Brain RNA - midbrain [nTPM]":"9.8","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"9.8","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"3.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"5.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"21.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.8","Single Cell Type RNA - Urothelial cells [nTPM]":"5.8"},{"Gene":"SLC5A7","Gene synonym":["CHT1","hCHT"],"Ensembl":"ENSG00000115665","Gene description":"Solute carrier family 5 member 7","Uniprot":["Q9GZV3"],"Chromosome":"2","Position":"107986523-108013994","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Neurotransmitter biosynthesis","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"32.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"3.2","Club cells":"3.1","Respiratory ciliated cells":"1.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"20","RNA cell line specific nTPM":{"RT4":"3.6","SCLC-21H":"1.0"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"23.1","hypothalamus":"9.0","midbrain":"9.4","pons and medulla":"14.4","thalamus":"6.2"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"20.4","pons":"26.5","spinal cord":"46.7"},"Antibody":["HPA046105"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Cell Junctions","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Cell Junctions","Intermediate filaments"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA046105":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"10.3","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"20.2","Tissue RNA - midbrain [nTPM]":"21.2","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"32.9","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"7.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.6","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"10.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"20.2","Brain RNA - midbrain [nTPM]":"21.2","Brain RNA - pons [nTPM]":"32.9","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"7.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"SLC6A1","Gene synonym":["GABATHG","GABATR","GAT1"],"Ensembl":"ENSG00000157103","Gene description":"Solute carrier family 6 member 1","Uniprot":["P30531"],"Chromosome":"3","Position":"10992186-11039247","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"71.3","liver":"87.3","retina":"37.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"221.0","Inhibitory neurons":"332.3","Microglial cells":"108.7","Oligodendrocyte precursor cells":"130.2","Oligodendrocytes":"107.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"16","RNA cancer specific FPKM":{"glioma":"16.1","liver cancer":"24.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"1.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013341","CAB022293"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022293":null,"HPA013341":"AB_1849509"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.05e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"51.5","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"56.0","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"45.4","Tissue RNA - cerebral cortex [nTPM]":"67.1","Tissue RNA - cervix [nTPM]":"3.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"9.1","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"4.1","Tissue RNA - hippocampal formation [nTPM]":"35.8","Tissue RNA - hypothalamus [nTPM]":"53.6","Tissue RNA - kidney [nTPM]":"2.9","Tissue RNA - liver [nTPM]":"87.3","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"39.4","Tissue RNA - midbrain [nTPM]":"63.5","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"15.9","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"34.8","Tissue RNA - prostate [nTPM]":"2.4","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"37.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"43.0","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"71.3","Tissue RNA - thymus [nTPM]":"17.6","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"39.4","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"1.6","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"51.5","Brain RNA - basal ganglia [nTPM]":"56.0","Brain RNA - cerebellum [nTPM]":"45.4","Brain RNA - cerebral cortex [nTPM]":"67.1","Brain RNA - hippocampal formation [nTPM]":"35.8","Brain RNA - hypothalamus [nTPM]":"53.6","Brain RNA - medulla oblongata [nTPM]":"39.4","Brain RNA - midbrain [nTPM]":"63.5","Brain RNA - pons [nTPM]":"34.8","Brain RNA - spinal cord [nTPM]":"43.0","Brain RNA - thalamus [nTPM]":"71.3","Brain RNA - white matter [nTPM]":"39.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"221.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"26.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"25.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"332.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"108.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"36.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"130.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"107.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC6A5","Gene synonym":["GLYT2","NET1"],"Ensembl":"ENSG00000165970","Gene description":"Solute carrier family 6 member 5","Uniprot":["Q9Y345"],"Chromosome":"11","Position":"20599594-20659285","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"brain":"22.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"39","RNA single cell type specific nTPM":{"Early spermatids":"20.6","Late spermatids":"66.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"medulla oblongata":"22.2","pons":"20.0","spinal cord":"7.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"pons and medulla":"49.3"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"medulla oblongata":"30.5","spinal cord":"18.3"},"Antibody":["CAB079052"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079052":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"22.2","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"20.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"22.2","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"20.0","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"20.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"66.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC7A14","Gene synonym":["KIAA1613","PPP1R142"],"Ensembl":"ENSG00000013293","Gene description":"Solute carrier family 7 member 14","Uniprot":["Q8TBB6"],"Chromosome":"3","Position":"170459548-170586075","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"15.9","pituitary gland":"7.3","retina":"6.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"28.4","Excitatory neurons":"61.9","Horizontal cells":"28.6","Inhibitory neurons":"90.2","Oligodendrocytes":"67.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"0.8","pancreatic cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"LHCN-M2":"3.2","SCLC-21H":"3.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045929"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA045929":"AB_2679501"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"8.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"8.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"7.9","Tissue RNA - hypothalamus [nTPM]":"15.9","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"14.9","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"7.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.1","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"8.1","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"8.8","Brain RNA - hippocampal formation [nTPM]":"7.9","Brain RNA - hypothalamus [nTPM]":"15.9","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"14.9","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"7.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"28.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"90.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"67.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"SLC9A1","Gene synonym":["APNH","NHE1","PPP1R143"],"Ensembl":"ENSG00000090020","Gene description":"Solute carrier family 9 member A1","Uniprot":["P19634"],"Chromosome":"1","Position":"27098809-27166981","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":["Calmodulin-binding"],"Disease involvement":["Deafness","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"76.5","stomach 1":"65.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"81.5","Gastric mucus-secreting cells":"160.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022371","HPA048532","HPA052891"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB022371":null,"HPA048532":"AB_2680431","HPA052891":"AB_2681981"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.47e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.10e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.6","Tissue RNA - adrenal gland [nTPM]":"10.7","Tissue RNA - amygdala [nTPM]":"6.1","Tissue RNA - appendix [nTPM]":"10.4","Tissue RNA - basal ganglia [nTPM]":"14.7","Tissue RNA - bone marrow [nTPM]":"11.5","Tissue RNA - breast [nTPM]":"9.0","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"10.9","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"18.6","Tissue RNA - duodenum [nTPM]":"29.3","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"16.9","Tissue RNA - heart muscle [nTPM]":"13.7","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"7.0","Tissue RNA - medulla oblongata [nTPM]":"13.8","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"8.6","Tissue RNA - parathyroid gland [nTPM]":"20.7","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"21.9","Tissue RNA - pons [nTPM]":"11.2","Tissue RNA - prostate [nTPM]":"9.0","Tissue RNA - rectum [nTPM]":"13.6","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"76.5","Tissue RNA - seminal vesicle [nTPM]":"19.4","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"10.5","Tissue RNA - small intestine [nTPM]":"19.0","Tissue RNA - smooth muscle [nTPM]":"10.7","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"11.6","Tissue RNA - stomach 1 [nTPM]":"65.9","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"10.4","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"4.9","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"15.1","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"32.3","Cell RNA - A549 [nTPM]":"10.7","Cell RNA - AF22 [nTPM]":"9.9","Cell RNA - AN3-CA [nTPM]":"10.1","Cell RNA - ASC diff [nTPM]":"21.8","Cell RNA - ASC TERT1 [nTPM]":"15.7","Cell RNA - BEWO [nTPM]":"60.8","Cell RNA - BJ [nTPM]":"25.9","Cell RNA - BJ hTERT+ [nTPM]":"38.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.5","Cell RNA - CACO-2 [nTPM]":"13.0","Cell RNA - CAPAN-2 [nTPM]":"20.0","Cell RNA - Daudi [nTPM]":"14.4","Cell RNA - EFO-21 [nTPM]":"21.9","Cell RNA - fHDF\/TERT166 [nTPM]":"33.4","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"38.9","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"62.4","Cell RNA - HBF TERT88 [nTPM]":"13.4","Cell RNA - HDLM-2 [nTPM]":"17.4","Cell RNA - HEK 293 [nTPM]":"9.4","Cell RNA - HEL [nTPM]":"21.9","Cell RNA - HeLa [nTPM]":"7.1","Cell RNA - Hep G2 [nTPM]":"5.5","Cell RNA - HHSteC [nTPM]":"66.1","Cell RNA - HL-60 [nTPM]":"13.1","Cell RNA - HMC-1 [nTPM]":"16.0","Cell RNA - HSkMC [nTPM]":"19.7","Cell RNA - hTCEpi [nTPM]":"29.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.5","Cell RNA - hTERT-HME1 [nTPM]":"50.7","Cell RNA - hTERT-RPE1 [nTPM]":"15.8","Cell RNA - HUVEC TERT2 [nTPM]":"36.3","Cell RNA - JURKAT [nTPM]":"9.8","Cell RNA - K-562 [nTPM]":"6.3","Cell RNA - Karpas-707 [nTPM]":"13.4","Cell RNA - LHCN-M2 [nTPM]":"32.3","Cell RNA - MCF7 [nTPM]":"18.7","Cell RNA - MOLT-4 [nTPM]":"6.8","Cell RNA - NB-4 [nTPM]":"6.4","Cell RNA - NTERA-2 [nTPM]":"14.0","Cell RNA - OE19 [nTPM]":"38.2","Cell RNA - PC-3 [nTPM]":"21.9","Cell RNA - REH [nTPM]":"11.8","Cell RNA - RH-30 [nTPM]":"9.0","Cell RNA - RPMI-8226 [nTPM]":"6.7","Cell RNA - RPTEC TERT1 [nTPM]":"10.9","Cell RNA - RT4 [nTPM]":"46.3","Cell RNA - SCLC-21H [nTPM]":"11.4","Cell RNA - SH-SY5Y [nTPM]":"3.7","Cell RNA - SiHa [nTPM]":"21.5","Cell RNA - SK-BR-3 [nTPM]":"28.4","Cell RNA - SK-MEL-30 [nTPM]":"12.6","Cell RNA - SuSa [nTPM]":"10.0","Cell RNA - T-47d [nTPM]":"13.3","Cell RNA - THP-1 [nTPM]":"7.9","Cell RNA - TIME [nTPM]":"39.9","Cell RNA - U-138 MG [nTPM]":"23.0","Cell RNA - U-2 OS [nTPM]":"9.4","Cell RNA - U-2197 [nTPM]":"21.7","Cell RNA - U-251 MG [nTPM]":"14.5","Cell RNA - U-266\/70 [nTPM]":"12.6","Cell RNA - U-266\/84 [nTPM]":"8.6","Cell RNA - U-698 [nTPM]":"4.3","Cell RNA - U-87 MG [nTPM]":"24.6","Cell RNA - U-937 [nTPM]":"14.1","Cell RNA - WM-115 [nTPM]":"13.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"6.1","Brain RNA - basal ganglia [nTPM]":"14.7","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"13.8","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"11.2","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"10.4","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"13.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.8","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"7.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"8.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.3","Single Cell Type RNA - dendritic cells [nTPM]":"11.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"81.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.1","Single Cell Type RNA - Early spermatids [nTPM]":"26.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.9","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.4","Single Cell Type RNA - Fibroblasts [nTPM]":"12.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"160.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.5","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.9","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"14.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"12.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"4.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.2","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.1","Single Cell Type RNA - Paneth cells [nTPM]":"43.1","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.9","Single Cell Type RNA - T-cells [nTPM]":"9.8","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.3","Single Cell Type RNA - Urothelial cells [nTPM]":"18.3"},{"Gene":"SMC1A","Gene synonym":["DXS423E","KIAA0178","SB1.8","SMC1L1","Smcb"],"Ensembl":"ENSG00000072501","Gene description":"Structural maintenance of chromosomes 1A","Uniprot":["Q14683"],"Chromosome":"X","Position":"53374149-53422728","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","DNA damage","DNA repair","Meiosis","Mitosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005499","CAB025404"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"33000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB025404":null,"HPA005499":"AB_1080028"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.6","Tissue RNA - adrenal gland [nTPM]":"11.8","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"28.4","Tissue RNA - basal ganglia [nTPM]":"11.7","Tissue RNA - bone marrow [nTPM]":"30.3","Tissue RNA - breast [nTPM]":"17.2","Tissue RNA - cerebellum [nTPM]":"15.0","Tissue RNA - cerebral cortex [nTPM]":"9.5","Tissue RNA - cervix [nTPM]":"13.8","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"20.0","Tissue RNA - duodenum [nTPM]":"18.6","Tissue RNA - endometrium 1 [nTPM]":"21.0","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"17.1","Tissue RNA - fallopian tube [nTPM]":"16.7","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"15.6","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"9.5","Tissue RNA - kidney [nTPM]":"16.3","Tissue RNA - liver [nTPM]":"18.8","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"34.4","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"10.7","Tissue RNA - ovary [nTPM]":"19.1","Tissue RNA - pancreas [nTPM]":"14.4","Tissue RNA - parathyroid gland [nTPM]":"25.8","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"18.2","Tissue RNA - pons [nTPM]":"10.7","Tissue RNA - prostate [nTPM]":"14.0","Tissue RNA - rectum [nTPM]":"18.4","Tissue RNA - retina [nTPM]":"21.0","Tissue RNA - salivary gland [nTPM]":"15.1","Tissue RNA - seminal vesicle [nTPM]":"13.0","Tissue RNA - skeletal muscle [nTPM]":"17.9","Tissue RNA - skin 1 [nTPM]":"18.1","Tissue RNA - small intestine [nTPM]":"15.9","Tissue RNA - smooth muscle [nTPM]":"22.9","Tissue RNA - spinal cord [nTPM]":"8.7","Tissue RNA - spleen [nTPM]":"20.1","Tissue RNA - stomach 1 [nTPM]":"15.7","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"58.1","Tissue RNA - thyroid gland [nTPM]":"16.8","Tissue RNA - tongue [nTPM]":"18.8","Tissue RNA - tonsil [nTPM]":"29.9","Tissue RNA - urinary bladder [nTPM]":"15.5","Tissue RNA - vagina [nTPM]":"12.4","Tissue RNA - white matter [nTPM]":"13.9","Cell RNA - A-431 [nTPM]":"110.0","Cell RNA - A549 [nTPM]":"115.1","Cell RNA - AF22 [nTPM]":"92.4","Cell RNA - AN3-CA [nTPM]":"76.1","Cell RNA - ASC diff [nTPM]":"32.4","Cell RNA - ASC TERT1 [nTPM]":"35.4","Cell RNA - BEWO [nTPM]":"51.5","Cell RNA - BJ [nTPM]":"68.0","Cell RNA - BJ hTERT+ [nTPM]":"37.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"76.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.4","Cell RNA - CACO-2 [nTPM]":"71.6","Cell RNA - CAPAN-2 [nTPM]":"60.5","Cell RNA - Daudi [nTPM]":"115.8","Cell RNA - EFO-21 [nTPM]":"54.1","Cell RNA - fHDF\/TERT166 [nTPM]":"40.7","Cell RNA - GAMG [nTPM]":"105.2","Cell RNA - HaCaT [nTPM]":"78.9","Cell RNA - HAP1 [nTPM]":"162.9","Cell RNA - HBEC3-KT [nTPM]":"92.6","Cell RNA - HBF TERT88 [nTPM]":"85.1","Cell RNA - HDLM-2 [nTPM]":"91.7","Cell RNA - HEK 293 [nTPM]":"176.0","Cell RNA - HEL [nTPM]":"94.3","Cell RNA - HeLa [nTPM]":"133.9","Cell RNA - Hep G2 [nTPM]":"51.1","Cell RNA - HHSteC [nTPM]":"15.4","Cell RNA - HL-60 [nTPM]":"134.9","Cell RNA - HMC-1 [nTPM]":"120.9","Cell RNA - HSkMC [nTPM]":"20.6","Cell RNA - hTCEpi [nTPM]":"23.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"86.0","Cell RNA - hTERT-HME1 [nTPM]":"52.8","Cell RNA - hTERT-RPE1 [nTPM]":"19.4","Cell RNA - HUVEC TERT2 [nTPM]":"67.5","Cell RNA - JURKAT [nTPM]":"68.7","Cell RNA - K-562 [nTPM]":"144.7","Cell RNA - Karpas-707 [nTPM]":"64.7","Cell RNA - LHCN-M2 [nTPM]":"58.6","Cell RNA - MCF7 [nTPM]":"69.2","Cell RNA - MOLT-4 [nTPM]":"122.0","Cell RNA - NB-4 [nTPM]":"40.8","Cell RNA - NTERA-2 [nTPM]":"139.9","Cell RNA - OE19 [nTPM]":"47.8","Cell RNA - PC-3 [nTPM]":"55.6","Cell RNA - REH [nTPM]":"117.2","Cell RNA - RH-30 [nTPM]":"165.5","Cell RNA - RPMI-8226 [nTPM]":"100.1","Cell RNA - RPTEC TERT1 [nTPM]":"34.4","Cell RNA - RT4 [nTPM]":"69.4","Cell RNA - SCLC-21H [nTPM]":"92.8","Cell RNA - SH-SY5Y [nTPM]":"83.5","Cell RNA - SiHa [nTPM]":"176.9","Cell RNA - SK-BR-3 [nTPM]":"84.4","Cell RNA - SK-MEL-30 [nTPM]":"33.5","Cell RNA - SuSa [nTPM]":"122.8","Cell RNA - T-47d [nTPM]":"87.9","Cell RNA - THP-1 [nTPM]":"54.0","Cell RNA - TIME [nTPM]":"45.7","Cell RNA - U-138 MG [nTPM]":"63.3","Cell RNA - U-2 OS [nTPM]":"68.0","Cell RNA - U-2197 [nTPM]":"65.1","Cell RNA - U-251 MG [nTPM]":"62.2","Cell RNA - U-266\/70 [nTPM]":"45.8","Cell RNA - U-266\/84 [nTPM]":"77.9","Cell RNA - U-698 [nTPM]":"91.9","Cell RNA - U-87 MG [nTPM]":"39.1","Cell RNA - U-937 [nTPM]":"152.1","Cell RNA - WM-115 [nTPM]":"64.1","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"6.8","Blood RNA - eosinophil [nTPM]":"4.5","Blood RNA - gdT-cell [nTPM]":"7.3","Blood RNA - intermediate monocyte [nTPM]":"8.5","Blood RNA - MAIT T-cell [nTPM]":"7.6","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.8","Blood RNA - memory CD8 T-cell [nTPM]":"6.7","Blood RNA - myeloid DC [nTPM]":"8.4","Blood RNA - naive B-cell [nTPM]":"5.8","Blood RNA - naive CD4 T-cell [nTPM]":"5.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.3","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"4.6","Blood RNA - non-classical monocyte [nTPM]":"12.4","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"5.7","Blood RNA - total PBMC [nTPM]":"6.7","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"11.7","Brain RNA - cerebellum [nTPM]":"15.0","Brain RNA - cerebral cortex [nTPM]":"9.5","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"9.5","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"10.7","Brain RNA - pons [nTPM]":"10.7","Brain RNA - spinal cord [nTPM]":"8.7","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"13.9","Single Cell Type RNA - Adipocytes [nTPM]":"40.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"39.9","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"45.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"46.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"63.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"47.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.2","Single Cell Type RNA - dendritic cells [nTPM]":"57.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"31.6","Single Cell Type RNA - Early spermatids [nTPM]":"10.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"46.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"62.6","Single Cell Type RNA - Endothelial cells [nTPM]":"41.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.9","Single Cell Type RNA - Erythroid cells [nTPM]":"70.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.4","Single Cell Type RNA - Fibroblasts [nTPM]":"37.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.0","Single Cell Type RNA - granulocytes [nTPM]":"35.4","Single Cell Type RNA - Granulosa cells [nTPM]":"42.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"54.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"47.6","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.5","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"41.1","Single Cell Type RNA - Langerhans cells [nTPM]":"27.6","Single Cell Type RNA - Late spermatids [nTPM]":"7.6","Single Cell Type RNA - Leydig cells [nTPM]":"37.9","Single Cell Type RNA - Macrophages [nTPM]":"51.5","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"55.2","Single Cell Type RNA - Muller glia cells [nTPM]":"38.1","Single Cell Type RNA - NK-cells [nTPM]":"59.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.1","Single Cell Type RNA - Paneth cells [nTPM]":"23.6","Single Cell Type RNA - Peritubular cells [nTPM]":"36.1","Single Cell Type RNA - Plasma cells [nTPM]":"61.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"47.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"49.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"71.0","Single Cell Type RNA - Spermatocytes [nTPM]":"54.5","Single Cell Type RNA - Spermatogonia [nTPM]":"51.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.4","Single Cell Type RNA - T-cells [nTPM]":"47.9","Single Cell Type RNA - Theca cells [nTPM]":"34.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.4","Single Cell Type RNA - Urothelial cells [nTPM]":"32.0"},{"Gene":"SMN1","Gene synonym":["BCD541","GEMIN1","SMA","SMA@","SMA1","SMA2","SMA3","SMNT","TDRD16A"],"Ensembl":"ENSG00000172062","Gene description":"Survival of motor neuron 1, telomeric","Uniprot":["Q16637"],"Chromosome":"5","Position":"70925030-70953942","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing","Neurogenesis"],"Molecular function":["RNA-binding"],"Disease involvement":["Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"29.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MOLT-4":"120.5","NB-4":"77.9","T-47d":"88.9","WM-115":"120.3"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016324","HPA045271","CAB069888","HPA073601"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Nuclear bodies","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB016324":"AB_627931","CAB069888":"AB_10001257","HPA045271":"AB_2679280","HPA073601":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.62e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.0","Tissue RNA - adrenal gland [nTPM]":"21.8","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"6.1","Tissue RNA - bone marrow [nTPM]":"21.8","Tissue RNA - breast [nTPM]":"26.8","Tissue RNA - cerebellum [nTPM]":"7.6","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"33.8","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"25.8","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"24.7","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"25.8","Tissue RNA - fallopian tube [nTPM]":"31.5","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"20.4","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"7.1","Tissue RNA - kidney [nTPM]":"22.6","Tissue RNA - liver [nTPM]":"37.6","Tissue RNA - lung [nTPM]":"22.0","Tissue RNA - lymph node [nTPM]":"15.5","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"5.7","Tissue RNA - ovary [nTPM]":"36.8","Tissue RNA - pancreas [nTPM]":"27.6","Tissue RNA - parathyroid gland [nTPM]":"6.9","Tissue RNA - pituitary gland [nTPM]":"26.4","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"25.6","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"12.1","Tissue RNA - salivary gland [nTPM]":"21.5","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"31.5","Tissue RNA - skin 1 [nTPM]":"24.0","Tissue RNA - small intestine [nTPM]":"19.6","Tissue RNA - smooth muscle [nTPM]":"8.2","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"22.6","Tissue RNA - stomach 1 [nTPM]":"20.3","Tissue RNA - testis [nTPM]":"24.8","Tissue RNA - thalamus [nTPM]":"5.7","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"24.2","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"26.1","Tissue RNA - vagina [nTPM]":"27.6","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"11.3","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"3.5","Cell RNA - AN3-CA [nTPM]":"4.0","Cell RNA - ASC diff [nTPM]":"19.3","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"62.8","Cell RNA - BJ [nTPM]":"3.5","Cell RNA - BJ hTERT+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.8","Cell RNA - CACO-2 [nTPM]":"4.1","Cell RNA - CAPAN-2 [nTPM]":"4.1","Cell RNA - Daudi [nTPM]":"4.6","Cell RNA - EFO-21 [nTPM]":"69.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.9","Cell RNA - GAMG [nTPM]":"5.8","Cell RNA - HaCaT [nTPM]":"7.4","Cell RNA - HAP1 [nTPM]":"5.4","Cell RNA - HBEC3-KT [nTPM]":"3.7","Cell RNA - HBF TERT88 [nTPM]":"4.2","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"65.4","Cell RNA - HeLa [nTPM]":"6.2","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"7.9","Cell RNA - HMC-1 [nTPM]":"5.8","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"29.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"1.8","Cell RNA - hTERT-RPE1 [nTPM]":"31.4","Cell RNA - HUVEC TERT2 [nTPM]":"3.0","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"6.4","Cell RNA - LHCN-M2 [nTPM]":"2.7","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"120.5","Cell RNA - NB-4 [nTPM]":"77.9","Cell RNA - NTERA-2 [nTPM]":"4.4","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"6.0","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"58.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.4","Cell RNA - RT4 [nTPM]":"5.2","Cell RNA - SCLC-21H [nTPM]":"11.4","Cell RNA - SH-SY5Y [nTPM]":"16.2","Cell RNA - SiHa [nTPM]":"6.5","Cell RNA - SK-BR-3 [nTPM]":"23.4","Cell RNA - SK-MEL-30 [nTPM]":"69.4","Cell RNA - SuSa [nTPM]":"2.4","Cell RNA - T-47d [nTPM]":"88.9","Cell RNA - THP-1 [nTPM]":"21.2","Cell RNA - TIME [nTPM]":"32.7","Cell RNA - U-138 MG [nTPM]":"33.8","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"3.1","Cell RNA - U-251 MG [nTPM]":"7.5","Cell RNA - U-266\/70 [nTPM]":"4.2","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"60.0","Cell RNA - U-87 MG [nTPM]":"4.9","Cell RNA - U-937 [nTPM]":"4.8","Cell RNA - WM-115 [nTPM]":"120.3","Blood RNA - basophil [nTPM]":"9.8","Blood RNA - classical monocyte [nTPM]":"7.4","Blood RNA - eosinophil [nTPM]":"4.3","Blood RNA - gdT-cell [nTPM]":"6.4","Blood RNA - intermediate monocyte [nTPM]":"12.2","Blood RNA - MAIT T-cell [nTPM]":"17.6","Blood RNA - memory B-cell [nTPM]":"13.2","Blood RNA - memory CD4 T-cell [nTPM]":"10.2","Blood RNA - memory CD8 T-cell [nTPM]":"7.7","Blood RNA - myeloid DC [nTPM]":"11.2","Blood RNA - naive B-cell [nTPM]":"7.2","Blood RNA - naive CD4 T-cell [nTPM]":"13.1","Blood RNA - naive CD8 T-cell [nTPM]":"14.5","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"8.7","Blood RNA - non-classical monocyte [nTPM]":"13.5","Blood RNA - plasmacytoid DC [nTPM]":"13.1","Blood RNA - T-reg [nTPM]":"16.1","Blood RNA - total PBMC [nTPM]":"6.3","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"6.1","Brain RNA - cerebellum [nTPM]":"7.6","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"7.1","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"5.7","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"5.7","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"5.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"29.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.9","Single Cell Type RNA - dendritic cells [nTPM]":"7.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.8","Single Cell Type RNA - Early spermatids [nTPM]":"18.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.5","Single Cell Type RNA - Endothelial cells [nTPM]":"6.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.4","Single Cell Type RNA - Fibroblasts [nTPM]":"11.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.4","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"4.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"12.9","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"5.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.8","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"5.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"16.0","Single Cell Type RNA - Spermatogonia [nTPM]":"17.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"5.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.2","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"SMN2","Gene synonym":["BCD541","GEMIN1","SMNC","TDRD16B"],"Ensembl":"ENSG00000205571","Gene description":"Survival of motor neuron 2, centromeric","Uniprot":["Q16637"],"Chromosome":"5","Position":"70049638-70078522","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing","Neurogenesis"],"Molecular function":["RNA-binding"],"Disease involvement":["Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"41.8","Club cells":"20.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"122.7","MOLT-4":"125.1","NB-4":"106.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009344","HPA045271","HPA073601"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Nuclear bodies","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009344":"AB_2193083","HPA045271":"AB_2679280","HPA073601":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.7","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"4.5","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"13.8","Tissue RNA - breast [nTPM]":"19.4","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"20.3","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"19.2","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"20.0","Tissue RNA - epididymis [nTPM]":"16.9","Tissue RNA - esophagus [nTPM]":"17.1","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"13.6","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"14.4","Tissue RNA - liver [nTPM]":"23.2","Tissue RNA - lung [nTPM]":"16.4","Tissue RNA - lymph node [nTPM]":"13.8","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"25.9","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"8.4","Tissue RNA - pituitary gland [nTPM]":"20.5","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"18.8","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"15.1","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"26.0","Tissue RNA - skin 1 [nTPM]":"17.0","Tissue RNA - small intestine [nTPM]":"13.6","Tissue RNA - smooth muscle [nTPM]":"14.0","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"14.7","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"16.5","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"16.0","Tissue RNA - vagina [nTPM]":"20.9","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"61.3","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"16.1","Cell RNA - ASC TERT1 [nTPM]":"20.9","Cell RNA - BEWO [nTPM]":"122.7","Cell RNA - BJ [nTPM]":"31.7","Cell RNA - BJ hTERT+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"44.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"1.2","Cell RNA - EFO-21 [nTPM]":"86.6","Cell RNA - fHDF\/TERT166 [nTPM]":"31.8","Cell RNA - GAMG [nTPM]":"1.1","Cell RNA - HaCaT [nTPM]":"28.8","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"50.1","Cell RNA - HDLM-2 [nTPM]":"0.8","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"68.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"36.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"14.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"125.1","Cell RNA - NB-4 [nTPM]":"106.2","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"45.8","Cell RNA - RPMI-8226 [nTPM]":"55.3","Cell RNA - RPTEC TERT1 [nTPM]":"31.5","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"30.5","Cell RNA - SH-SY5Y [nTPM]":"70.7","Cell RNA - SiHa [nTPM]":"60.2","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"89.7","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"41.4","Cell RNA - THP-1 [nTPM]":"25.2","Cell RNA - TIME [nTPM]":"53.4","Cell RNA - U-138 MG [nTPM]":"27.2","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"72.4","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"76.2","Blood RNA - basophil [nTPM]":"8.0","Blood RNA - classical monocyte [nTPM]":"9.9","Blood RNA - eosinophil [nTPM]":"5.2","Blood RNA - gdT-cell [nTPM]":"12.1","Blood RNA - intermediate monocyte [nTPM]":"16.5","Blood RNA - MAIT T-cell [nTPM]":"14.6","Blood RNA - memory B-cell [nTPM]":"16.8","Blood RNA - memory CD4 T-cell [nTPM]":"14.4","Blood RNA - memory CD8 T-cell [nTPM]":"10.1","Blood RNA - myeloid DC [nTPM]":"16.6","Blood RNA - naive B-cell [nTPM]":"20.0","Blood RNA - naive CD4 T-cell [nTPM]":"17.0","Blood RNA - naive CD8 T-cell [nTPM]":"14.8","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"10.9","Blood RNA - non-classical monocyte [nTPM]":"11.4","Blood RNA - plasmacytoid DC [nTPM]":"16.3","Blood RNA - T-reg [nTPM]":"12.7","Blood RNA - total PBMC [nTPM]":"13.4","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"20.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.9","Single Cell Type RNA - dendritic cells [nTPM]":"4.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.7","Single Cell Type RNA - Early spermatids [nTPM]":"14.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.3","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"3.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.6","Single Cell Type RNA - Langerhans cells [nTPM]":"6.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.9","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"2.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.4","Single Cell Type RNA - Spermatocytes [nTPM]":"12.0","Single Cell Type RNA - Spermatogonia [nTPM]":"11.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.5","Single Cell Type RNA - Urothelial cells [nTPM]":"2.8"},{"Gene":"SMPX","Gene synonym":["Chisel","Csl","DFN6","DFNX4"],"Ensembl":"ENSG00000091482","Gene description":"Small muscle protein X-linked","Uniprot":["Q9UHP9"],"Chromosome":"X","Position":"21705978-21758116","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"39","RNA tissue specific nTPM":{"heart muscle":"757.5","skeletal muscle":"1183.4","tongue":"1097.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Cardiomyocytes":"807.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"head and neck cancer":"7.2","stomach cancer":"1.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"GAMG":"23.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077360"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"62000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA077360":"AB_2732342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.04e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"25.6","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"20.0","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"757.5","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"3.3","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"11.1","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"17.8","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"1183.4","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"4.1","Tissue RNA - smooth muscle [nTPM]":"12.6","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"7.2","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"1097.5","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"3.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"23.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"4.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"4.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"3.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"4.6","Cell RNA - U-266\/84 [nTPM]":"1.8","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"3.3","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"807.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"16.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SNAP25","Gene synonym":["bA416N4.2","dJ1068F16.2","RIC-4","RIC4","SEC9","SNAP","SNAP-25"],"Ensembl":"ENSG00000132639","Gene description":"Synaptosome associated protein 25","Uniprot":["P60880"],"Chromosome":"20","Position":"10218830-10307418","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant","FDA approved drug targets","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"20","RNA tissue specific nTPM":{"brain":"1658.7","retina":"492.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"559.2","Excitatory neurons":"1015.8","Inhibitory neurons":"552.8","Rod photoreceptor cells":"254.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"28.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"23.8","SCLC-21H":"78.2","SH-SY5Y":"46.6","U-87 MG":"56.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000360","HPA001830","HPA071013"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB000360":"AB_2286342","HPA001830":"AB_1080039","HPA071013":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"43.6","Tissue RNA - amygdala [nTPM]":"251.0","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"383.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"598.0","Tissue RNA - cerebral cortex [nTPM]":"1658.7","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"7.9","Tissue RNA - epididymis [nTPM]":"12.9","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"3.2","Tissue RNA - hippocampal formation [nTPM]":"420.4","Tissue RNA - hypothalamus [nTPM]":"142.2","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"427.4","Tissue RNA - midbrain [nTPM]":"24.7","Tissue RNA - ovary [nTPM]":"6.9","Tissue RNA - pancreas [nTPM]":"6.3","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"54.3","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"386.6","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"492.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"19.6","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"38.1","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"147.6","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"726.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"4.7","Cell RNA - AF22 [nTPM]":"3.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.4","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"9.6","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"6.8","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"3.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"4.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.9","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"23.8","Cell RNA - LHCN-M2 [nTPM]":"1.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"3.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"78.2","Cell RNA - SH-SY5Y [nTPM]":"46.6","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"6.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"5.0","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"2.3","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"12.9","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"56.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"251.0","Brain RNA - basal ganglia [nTPM]":"383.5","Brain RNA - cerebellum [nTPM]":"598.0","Brain RNA - cerebral cortex [nTPM]":"1658.7","Brain RNA - hippocampal formation [nTPM]":"420.4","Brain RNA - hypothalamus [nTPM]":"142.2","Brain RNA - medulla oblongata [nTPM]":"427.4","Brain RNA - midbrain [nTPM]":"24.7","Brain RNA - pons [nTPM]":"386.6","Brain RNA - spinal cord [nTPM]":"38.1","Brain RNA - thalamus [nTPM]":"147.6","Brain RNA - white matter [nTPM]":"726.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"117.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"559.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"106.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"16.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"5.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1015.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"65.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"552.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"83.3","Single Cell Type RNA - Leydig cells [nTPM]":"17.1","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"120.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"71.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"179.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"113.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"68.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"254.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"2.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SNCA","Gene synonym":["NACP","PARK1","PARK4","PD1"],"Ensembl":"ENSG00000145335","Gene description":"Synuclein alpha","Uniprot":["P37840"],"Chromosome":"4","Position":"89700345-89838315","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Alzheimer disease","Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"273.6","brain":"128.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"1225.0","Excitatory neurons":"251.5","Melanocytes":"352.2","Oligodendrocytes":"195.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"melanoma":"37.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"102.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"102.9","granulocytes":"51.5","monocytes":"66.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"221.5","HUVEC TERT2":"269.8","RT4":"137.3","SK-MEL-30":"271.6","TIME":"311.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005459","CAB010877"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010877":"AB_261518","HPA005459":"AB_2667324"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-3"},"Tissue RNA - adipose tissue [nTPM]":"16.0","Tissue RNA - adrenal gland [nTPM]":"9.9","Tissue RNA - amygdala [nTPM]":"91.5","Tissue RNA - appendix [nTPM]":"10.0","Tissue RNA - basal ganglia [nTPM]":"112.2","Tissue RNA - bone marrow [nTPM]":"273.6","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"47.2","Tissue RNA - cerebral cortex [nTPM]":"128.2","Tissue RNA - cervix [nTPM]":"26.1","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"28.5","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"34.3","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"8.5","Tissue RNA - fallopian tube [nTPM]":"11.2","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"20.9","Tissue RNA - hippocampal formation [nTPM]":"115.2","Tissue RNA - hypothalamus [nTPM]":"69.1","Tissue RNA - kidney [nTPM]":"12.4","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"16.6","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"97.5","Tissue RNA - midbrain [nTPM]":"88.3","Tissue RNA - ovary [nTPM]":"29.3","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"28.7","Tissue RNA - placenta [nTPM]":"28.3","Tissue RNA - pons [nTPM]":"89.9","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"20.3","Tissue RNA - salivary gland [nTPM]":"15.9","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"16.4","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"33.3","Tissue RNA - spinal cord [nTPM]":"36.0","Tissue RNA - spleen [nTPM]":"15.2","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"76.2","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"8.5","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"23.2","Tissue RNA - white matter [nTPM]":"107.0","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"40.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"44.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"9.3","Cell RNA - HAP1 [nTPM]":"53.6","Cell RNA - HBEC3-KT [nTPM]":"97.7","Cell RNA - HBF TERT88 [nTPM]":"1.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"22.6","Cell RNA - HEL [nTPM]":"221.5","Cell RNA - HeLa [nTPM]":"115.4","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"84.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.4","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"38.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"109.5","Cell RNA - hTERT-RPE1 [nTPM]":"117.3","Cell RNA - HUVEC TERT2 [nTPM]":"269.8","Cell RNA - JURKAT [nTPM]":"2.2","Cell RNA - K-562 [nTPM]":"2.0","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"2.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"10.6","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"4.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"15.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"137.3","Cell RNA - SCLC-21H [nTPM]":"23.2","Cell RNA - SH-SY5Y [nTPM]":"15.6","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"271.6","Cell RNA - SuSa [nTPM]":"29.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"311.4","Cell RNA - U-138 MG [nTPM]":"1.3","Cell RNA - U-2 OS [nTPM]":"8.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"8.8","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"87.4","Blood RNA - basophil [nTPM]":"51.5","Blood RNA - classical monocyte [nTPM]":"66.9","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"27.7","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"4.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"84.6","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"11.1","Blood RNA - NK-cell [nTPM]":"17.3","Blood RNA - non-classical monocyte [nTPM]":"8.2","Blood RNA - plasmacytoid DC [nTPM]":"102.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"63.7","Brain RNA - amygdala [nTPM]":"91.5","Brain RNA - basal ganglia [nTPM]":"112.2","Brain RNA - cerebellum [nTPM]":"47.2","Brain RNA - cerebral cortex [nTPM]":"128.2","Brain RNA - hippocampal formation [nTPM]":"115.2","Brain RNA - hypothalamus [nTPM]":"69.1","Brain RNA - medulla oblongata [nTPM]":"97.5","Brain RNA - midbrain [nTPM]":"88.3","Brain RNA - pons [nTPM]":"89.9","Brain RNA - spinal cord [nTPM]":"36.0","Brain RNA - thalamus [nTPM]":"76.2","Brain RNA - white matter [nTPM]":"107.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"40.1","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"76.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"173.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"101.3","Single Cell Type RNA - Bipolar cells [nTPM]":"10.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"21.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"19.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1225.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"251.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"32.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"23.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"62.3","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"17.2","Single Cell Type RNA - Langerhans cells [nTPM]":"64.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"100.7","Single Cell Type RNA - Melanocytes [nTPM]":"352.2","Single Cell Type RNA - Microglial cells [nTPM]":"76.8","Single Cell Type RNA - monocytes [nTPM]":"24.4","Single Cell Type RNA - Muller glia cells [nTPM]":"19.4","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"95.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"195.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"19.6","Single Cell Type RNA - Spermatogonia [nTPM]":"16.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"43.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"SNCB","Gene synonym":[],"Ensembl":"ENSG00000074317","Gene description":"Synuclein beta","Uniprot":["Q16143"],"Chromosome":"5","Position":"176620082-176630556","Protein class":["Human disease related genes","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"brain":"439.2","retina":"182.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"105.1","Excitatory neurons":"36.8","Horizontal cells":"50.5","Inhibitory neurons":"32.6","Rod photoreceptor cells":"49.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"11.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"SCLC-21H":"54.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002681","HPA035876"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002681":null,"HPA035876":"AB_10670592"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"3.2","Tissue RNA - amygdala [nTPM]":"81.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"154.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"74.3","Tissue RNA - cerebral cortex [nTPM]":"439.2","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"136.3","Tissue RNA - hypothalamus [nTPM]":"41.9","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"104.2","Tissue RNA - midbrain [nTPM]":"23.8","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"17.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"77.7","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"182.2","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"63.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"237.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"1.8","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"6.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"2.7","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"54.6","Cell RNA - SH-SY5Y [nTPM]":"2.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"5.4","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"2.5","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"81.7","Brain RNA - basal ganglia [nTPM]":"154.5","Brain RNA - cerebellum [nTPM]":"74.3","Brain RNA - cerebral cortex [nTPM]":"439.2","Brain RNA - hippocampal formation [nTPM]":"136.3","Brain RNA - hypothalamus [nTPM]":"41.9","Brain RNA - medulla oblongata [nTPM]":"104.2","Brain RNA - midbrain [nTPM]":"23.8","Brain RNA - pons [nTPM]":"77.7","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"63.1","Brain RNA - white matter [nTPM]":"237.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"105.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"10.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SNRNP200","Gene synonym":["ASCC3L1","BRR2","HELIC2","KIAA0788","RP33","U5-200KD"],"Ensembl":"ENSG00000144028","Gene description":"Small nuclear ribonucleoprotein U5 subunit 200","Uniprot":["O75643"],"Chromosome":"2","Position":"96274338-96321271","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029321"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA029321":"AB_10604096"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.89e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.5","Tissue RNA - adrenal gland [nTPM]":"21.8","Tissue RNA - amygdala [nTPM]":"11.2","Tissue RNA - appendix [nTPM]":"38.1","Tissue RNA - basal ganglia [nTPM]":"11.3","Tissue RNA - bone marrow [nTPM]":"58.8","Tissue RNA - breast [nTPM]":"38.6","Tissue RNA - cerebellum [nTPM]":"16.9","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"31.9","Tissue RNA - choroid plexus [nTPM]":"25.5","Tissue RNA - colon [nTPM]":"29.6","Tissue RNA - duodenum [nTPM]":"29.4","Tissue RNA - endometrium 1 [nTPM]":"41.0","Tissue RNA - epididymis [nTPM]":"20.2","Tissue RNA - esophagus [nTPM]":"29.5","Tissue RNA - fallopian tube [nTPM]":"39.8","Tissue RNA - gallbladder [nTPM]":"25.8","Tissue RNA - heart muscle [nTPM]":"26.9","Tissue RNA - hippocampal formation [nTPM]":"9.9","Tissue RNA - hypothalamus [nTPM]":"11.1","Tissue RNA - kidney [nTPM]":"28.8","Tissue RNA - liver [nTPM]":"29.3","Tissue RNA - lung [nTPM]":"29.3","Tissue RNA - lymph node [nTPM]":"43.2","Tissue RNA - medulla oblongata [nTPM]":"13.1","Tissue RNA - midbrain [nTPM]":"10.3","Tissue RNA - ovary [nTPM]":"53.2","Tissue RNA - pancreas [nTPM]":"34.3","Tissue RNA - parathyroid gland [nTPM]":"52.4","Tissue RNA - pituitary gland [nTPM]":"19.7","Tissue RNA - placenta [nTPM]":"39.2","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"31.6","Tissue RNA - rectum [nTPM]":"34.6","Tissue RNA - retina [nTPM]":"67.6","Tissue RNA - salivary gland [nTPM]":"35.1","Tissue RNA - seminal vesicle [nTPM]":"33.0","Tissue RNA - skeletal muscle [nTPM]":"47.4","Tissue RNA - skin 1 [nTPM]":"30.8","Tissue RNA - small intestine [nTPM]":"30.3","Tissue RNA - smooth muscle [nTPM]":"38.5","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"36.5","Tissue RNA - stomach 1 [nTPM]":"30.6","Tissue RNA - testis [nTPM]":"40.4","Tissue RNA - thalamus [nTPM]":"9.8","Tissue RNA - thymus [nTPM]":"73.5","Tissue RNA - thyroid gland [nTPM]":"37.4","Tissue RNA - tongue [nTPM]":"38.7","Tissue RNA - tonsil [nTPM]":"52.3","Tissue RNA - urinary bladder [nTPM]":"30.1","Tissue RNA - vagina [nTPM]":"21.6","Tissue RNA - white matter [nTPM]":"14.6","Cell RNA - A-431 [nTPM]":"97.8","Cell RNA - A549 [nTPM]":"107.7","Cell RNA - AF22 [nTPM]":"144.1","Cell RNA - AN3-CA [nTPM]":"106.1","Cell RNA - ASC diff [nTPM]":"63.1","Cell RNA - ASC TERT1 [nTPM]":"57.1","Cell RNA - BEWO [nTPM]":"131.5","Cell RNA - BJ [nTPM]":"67.3","Cell RNA - BJ hTERT+ [nTPM]":"80.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"119.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"112.9","Cell RNA - CACO-2 [nTPM]":"197.3","Cell RNA - CAPAN-2 [nTPM]":"69.3","Cell RNA - Daudi [nTPM]":"169.3","Cell RNA - EFO-21 [nTPM]":"101.3","Cell RNA - fHDF\/TERT166 [nTPM]":"83.3","Cell RNA - GAMG [nTPM]":"178.9","Cell RNA - HaCaT [nTPM]":"74.9","Cell RNA - HAP1 [nTPM]":"264.4","Cell RNA - HBEC3-KT [nTPM]":"88.8","Cell RNA - HBF TERT88 [nTPM]":"130.8","Cell RNA - HDLM-2 [nTPM]":"94.3","Cell RNA - HEK 293 [nTPM]":"139.4","Cell RNA - HEL [nTPM]":"221.6","Cell RNA - HeLa [nTPM]":"169.8","Cell RNA - Hep G2 [nTPM]":"106.7","Cell RNA - HHSteC [nTPM]":"40.9","Cell RNA - HL-60 [nTPM]":"171.2","Cell RNA - HMC-1 [nTPM]":"92.4","Cell RNA - HSkMC [nTPM]":"58.1","Cell RNA - hTCEpi [nTPM]":"53.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"133.2","Cell RNA - hTERT-HME1 [nTPM]":"112.0","Cell RNA - hTERT-RPE1 [nTPM]":"61.3","Cell RNA - HUVEC TERT2 [nTPM]":"97.3","Cell RNA - JURKAT [nTPM]":"98.3","Cell RNA - K-562 [nTPM]":"198.2","Cell RNA - Karpas-707 [nTPM]":"112.3","Cell RNA - LHCN-M2 [nTPM]":"68.3","Cell RNA - MCF7 [nTPM]":"82.3","Cell RNA - MOLT-4 [nTPM]":"158.8","Cell RNA - NB-4 [nTPM]":"49.4","Cell RNA - NTERA-2 [nTPM]":"182.8","Cell RNA - OE19 [nTPM]":"77.9","Cell RNA - PC-3 [nTPM]":"102.4","Cell RNA - REH [nTPM]":"185.0","Cell RNA - RH-30 [nTPM]":"139.3","Cell RNA - RPMI-8226 [nTPM]":"107.4","Cell RNA - RPTEC TERT1 [nTPM]":"43.8","Cell RNA - RT4 [nTPM]":"145.4","Cell RNA - SCLC-21H [nTPM]":"159.8","Cell RNA - SH-SY5Y [nTPM]":"150.5","Cell RNA - SiHa [nTPM]":"107.7","Cell RNA - SK-BR-3 [nTPM]":"88.7","Cell RNA - SK-MEL-30 [nTPM]":"65.4","Cell RNA - SuSa [nTPM]":"165.0","Cell RNA - T-47d [nTPM]":"86.4","Cell RNA - THP-1 [nTPM]":"100.5","Cell RNA - TIME [nTPM]":"86.2","Cell RNA - U-138 MG [nTPM]":"98.3","Cell RNA - U-2 OS [nTPM]":"117.2","Cell RNA - U-2197 [nTPM]":"101.3","Cell RNA - U-251 MG [nTPM]":"96.2","Cell RNA - U-266\/70 [nTPM]":"101.0","Cell RNA - U-266\/84 [nTPM]":"134.0","Cell RNA - U-698 [nTPM]":"207.6","Cell RNA - U-87 MG [nTPM]":"66.2","Cell RNA - U-937 [nTPM]":"109.0","Cell RNA - WM-115 [nTPM]":"106.2","Blood RNA - basophil [nTPM]":"16.7","Blood RNA - classical monocyte [nTPM]":"4.7","Blood RNA - eosinophil [nTPM]":"6.0","Blood RNA - gdT-cell [nTPM]":"7.9","Blood RNA - intermediate monocyte [nTPM]":"5.0","Blood RNA - MAIT T-cell [nTPM]":"8.9","Blood RNA - memory B-cell [nTPM]":"5.7","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"9.5","Blood RNA - myeloid DC [nTPM]":"5.6","Blood RNA - naive B-cell [nTPM]":"6.1","Blood RNA - naive CD4 T-cell [nTPM]":"5.2","Blood RNA - naive CD8 T-cell [nTPM]":"7.1","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"7.3","Blood RNA - non-classical monocyte [nTPM]":"6.1","Blood RNA - plasmacytoid DC [nTPM]":"5.8","Blood RNA - T-reg [nTPM]":"6.8","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"11.2","Brain RNA - basal ganglia [nTPM]":"11.3","Brain RNA - cerebellum [nTPM]":"16.9","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"9.9","Brain RNA - hypothalamus [nTPM]":"11.1","Brain RNA - medulla oblongata [nTPM]":"13.1","Brain RNA - midbrain [nTPM]":"10.3","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"9.8","Brain RNA - white matter [nTPM]":"14.6","Single Cell Type RNA - Adipocytes [nTPM]":"47.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.9","Single Cell Type RNA - Astrocytes [nTPM]":"21.9","Single Cell Type RNA - B-cells [nTPM]":"57.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"35.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"79.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"46.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"104.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.2","Single Cell Type RNA - dendritic cells [nTPM]":"64.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"43.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"42.6","Single Cell Type RNA - Early spermatids [nTPM]":"29.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"48.7","Single Cell Type RNA - Endothelial cells [nTPM]":"44.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.7","Single Cell Type RNA - Erythroid cells [nTPM]":"54.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"46.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.1","Single Cell Type RNA - Fibroblasts [nTPM]":"37.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.8","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"79.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.4","Single Cell Type RNA - Hepatocytes [nTPM]":"49.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.1","Single Cell Type RNA - Horizontal cells [nTPM]":"87.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.6","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"31.9","Single Cell Type RNA - Langerhans cells [nTPM]":"33.2","Single Cell Type RNA - Late spermatids [nTPM]":"18.2","Single Cell Type RNA - Leydig cells [nTPM]":"57.5","Single Cell Type RNA - Macrophages [nTPM]":"35.2","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"45.2","Single Cell Type RNA - Muller glia cells [nTPM]":"79.1","Single Cell Type RNA - NK-cells [nTPM]":"73.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"46.1","Single Cell Type RNA - Paneth cells [nTPM]":"30.7","Single Cell Type RNA - Peritubular cells [nTPM]":"55.3","Single Cell Type RNA - Plasma cells [nTPM]":"68.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"135.2","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.5","Single Cell Type RNA - Spermatocytes [nTPM]":"77.6","Single Cell Type RNA - Spermatogonia [nTPM]":"56.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"44.6","Single Cell Type RNA - T-cells [nTPM]":"71.6","Single Cell Type RNA - Theca cells [nTPM]":"53.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.4","Single Cell Type RNA - Urothelial cells [nTPM]":"30.3"},{"Gene":"SNX14","Gene synonym":["RGS-PX2"],"Ensembl":"ENSG00000135317","Gene description":"Sorting nexin 14","Uniprot":["Q9Y5W7"],"Chromosome":"6","Position":"85505496-85594156","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"173.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017639"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017639":"AB_1857345"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"27.3","Tissue RNA - adrenal gland [nTPM]":"39.9","Tissue RNA - amygdala [nTPM]":"39.0","Tissue RNA - appendix [nTPM]":"23.0","Tissue RNA - basal ganglia [nTPM]":"40.5","Tissue RNA - bone marrow [nTPM]":"31.4","Tissue RNA - breast [nTPM]":"41.7","Tissue RNA - cerebellum [nTPM]":"44.4","Tissue RNA - cerebral cortex [nTPM]":"61.0","Tissue RNA - cervix [nTPM]":"30.8","Tissue RNA - choroid plexus [nTPM]":"49.7","Tissue RNA - colon [nTPM]":"39.7","Tissue RNA - duodenum [nTPM]":"29.8","Tissue RNA - endometrium 1 [nTPM]":"23.5","Tissue RNA - epididymis [nTPM]":"57.3","Tissue RNA - esophagus [nTPM]":"24.3","Tissue RNA - fallopian tube [nTPM]":"28.2","Tissue RNA - gallbladder [nTPM]":"28.3","Tissue RNA - heart muscle [nTPM]":"24.8","Tissue RNA - hippocampal formation [nTPM]":"40.7","Tissue RNA - hypothalamus [nTPM]":"47.0","Tissue RNA - kidney [nTPM]":"54.4","Tissue RNA - liver [nTPM]":"69.6","Tissue RNA - lung [nTPM]":"39.6","Tissue RNA - lymph node [nTPM]":"32.6","Tissue RNA - medulla oblongata [nTPM]":"40.1","Tissue RNA - midbrain [nTPM]":"40.7","Tissue RNA - ovary [nTPM]":"26.8","Tissue RNA - pancreas [nTPM]":"43.6","Tissue RNA - parathyroid gland [nTPM]":"47.1","Tissue RNA - pituitary gland [nTPM]":"36.3","Tissue RNA - placenta [nTPM]":"36.2","Tissue RNA - pons [nTPM]":"43.1","Tissue RNA - prostate [nTPM]":"33.2","Tissue RNA - rectum [nTPM]":"35.1","Tissue RNA - retina [nTPM]":"47.2","Tissue RNA - salivary gland [nTPM]":"27.8","Tissue RNA - seminal vesicle [nTPM]":"30.8","Tissue RNA - skeletal muscle [nTPM]":"16.4","Tissue RNA - skin 1 [nTPM]":"28.6","Tissue RNA - small intestine [nTPM]":"31.7","Tissue RNA - smooth muscle [nTPM]":"22.4","Tissue RNA - spinal cord [nTPM]":"40.9","Tissue RNA - spleen [nTPM]":"37.4","Tissue RNA - stomach 1 [nTPM]":"45.3","Tissue RNA - testis [nTPM]":"87.0","Tissue RNA - thalamus [nTPM]":"42.5","Tissue RNA - thymus [nTPM]":"18.9","Tissue RNA - thyroid gland [nTPM]":"40.5","Tissue RNA - tongue [nTPM]":"12.9","Tissue RNA - tonsil [nTPM]":"28.8","Tissue RNA - urinary bladder [nTPM]":"35.1","Tissue RNA - vagina [nTPM]":"24.7","Tissue RNA - white matter [nTPM]":"44.2","Cell RNA - A-431 [nTPM]":"46.1","Cell RNA - A549 [nTPM]":"27.3","Cell RNA - AF22 [nTPM]":"44.5","Cell RNA - AN3-CA [nTPM]":"64.9","Cell RNA - ASC diff [nTPM]":"98.3","Cell RNA - ASC TERT1 [nTPM]":"71.6","Cell RNA - BEWO [nTPM]":"46.0","Cell RNA - BJ [nTPM]":"58.0","Cell RNA - BJ hTERT+ [nTPM]":"78.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"67.5","Cell RNA - CACO-2 [nTPM]":"49.0","Cell RNA - CAPAN-2 [nTPM]":"75.4","Cell RNA - Daudi [nTPM]":"60.3","Cell RNA - EFO-21 [nTPM]":"69.8","Cell RNA - fHDF\/TERT166 [nTPM]":"74.4","Cell RNA - GAMG [nTPM]":"85.9","Cell RNA - HaCaT [nTPM]":"60.7","Cell RNA - HAP1 [nTPM]":"30.5","Cell RNA - HBEC3-KT [nTPM]":"58.8","Cell RNA - HBF TERT88 [nTPM]":"69.4","Cell RNA - HDLM-2 [nTPM]":"53.3","Cell RNA - HEK 293 [nTPM]":"18.0","Cell RNA - HEL [nTPM]":"66.1","Cell RNA - HeLa [nTPM]":"36.4","Cell RNA - Hep G2 [nTPM]":"75.1","Cell RNA - HHSteC [nTPM]":"80.9","Cell RNA - HL-60 [nTPM]":"62.4","Cell RNA - HMC-1 [nTPM]":"65.0","Cell RNA - HSkMC [nTPM]":"63.0","Cell RNA - hTCEpi [nTPM]":"43.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"52.0","Cell RNA - hTERT-HME1 [nTPM]":"51.6","Cell RNA - hTERT-RPE1 [nTPM]":"81.1","Cell RNA - HUVEC TERT2 [nTPM]":"79.4","Cell RNA - JURKAT [nTPM]":"23.2","Cell RNA - K-562 [nTPM]":"67.7","Cell RNA - Karpas-707 [nTPM]":"50.4","Cell RNA - LHCN-M2 [nTPM]":"96.9","Cell RNA - MCF7 [nTPM]":"52.1","Cell RNA - MOLT-4 [nTPM]":"4.4","Cell RNA - NB-4 [nTPM]":"117.0","Cell RNA - NTERA-2 [nTPM]":"18.3","Cell RNA - OE19 [nTPM]":"72.1","Cell RNA - PC-3 [nTPM]":"31.1","Cell RNA - REH [nTPM]":"26.2","Cell RNA - RH-30 [nTPM]":"90.6","Cell RNA - RPMI-8226 [nTPM]":"29.1","Cell RNA - RPTEC TERT1 [nTPM]":"107.1","Cell RNA - RT4 [nTPM]":"82.7","Cell RNA - SCLC-21H [nTPM]":"19.8","Cell RNA - SH-SY5Y [nTPM]":"44.5","Cell RNA - SiHa [nTPM]":"35.0","Cell RNA - SK-BR-3 [nTPM]":"76.6","Cell RNA - SK-MEL-30 [nTPM]":"56.3","Cell RNA - SuSa [nTPM]":"57.9","Cell RNA - T-47d [nTPM]":"47.9","Cell RNA - THP-1 [nTPM]":"108.9","Cell RNA - TIME [nTPM]":"71.6","Cell RNA - U-138 MG [nTPM]":"35.4","Cell RNA - U-2 OS [nTPM]":"21.8","Cell RNA - U-2197 [nTPM]":"44.1","Cell RNA - U-251 MG [nTPM]":"60.3","Cell RNA - U-266\/70 [nTPM]":"50.4","Cell RNA - U-266\/84 [nTPM]":"87.0","Cell RNA - U-698 [nTPM]":"22.8","Cell RNA - U-87 MG [nTPM]":"71.3","Cell RNA - U-937 [nTPM]":"72.2","Cell RNA - WM-115 [nTPM]":"71.8","Blood RNA - basophil [nTPM]":"36.7","Blood RNA - classical monocyte [nTPM]":"21.5","Blood RNA - eosinophil [nTPM]":"33.0","Blood RNA - gdT-cell [nTPM]":"19.9","Blood RNA - intermediate monocyte [nTPM]":"33.6","Blood RNA - MAIT T-cell [nTPM]":"14.7","Blood RNA - memory B-cell [nTPM]":"13.3","Blood RNA - memory CD4 T-cell [nTPM]":"13.4","Blood RNA - memory CD8 T-cell [nTPM]":"18.1","Blood RNA - myeloid DC [nTPM]":"26.2","Blood RNA - naive B-cell [nTPM]":"14.7","Blood RNA - naive CD4 T-cell [nTPM]":"12.0","Blood RNA - naive CD8 T-cell [nTPM]":"15.0","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"22.9","Blood RNA - non-classical monocyte [nTPM]":"40.9","Blood RNA - plasmacytoid DC [nTPM]":"7.9","Blood RNA - T-reg [nTPM]":"16.7","Blood RNA - total PBMC [nTPM]":"15.7","Brain RNA - amygdala [nTPM]":"39.0","Brain RNA - basal ganglia [nTPM]":"40.5","Brain RNA - cerebellum [nTPM]":"44.4","Brain RNA - cerebral cortex [nTPM]":"61.0","Brain RNA - hippocampal formation [nTPM]":"40.7","Brain RNA - hypothalamus [nTPM]":"47.0","Brain RNA - medulla oblongata [nTPM]":"40.1","Brain RNA - midbrain [nTPM]":"40.7","Brain RNA - pons [nTPM]":"43.1","Brain RNA - spinal cord [nTPM]":"40.9","Brain RNA - thalamus [nTPM]":"42.5","Brain RNA - white matter [nTPM]":"44.2","Single Cell Type RNA - Adipocytes [nTPM]":"28.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"93.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.2","Single Cell Type RNA - Astrocytes [nTPM]":"76.4","Single Cell Type RNA - B-cells [nTPM]":"25.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"36.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"39.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"50.4","Single Cell Type RNA - dendritic cells [nTPM]":"32.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"31.7","Single Cell Type RNA - Early spermatids [nTPM]":"87.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.2","Single Cell Type RNA - Endothelial cells [nTPM]":"26.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.8","Single Cell Type RNA - Erythroid cells [nTPM]":"13.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"115.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"41.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.9","Single Cell Type RNA - Fibroblasts [nTPM]":"23.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.5","Single Cell Type RNA - granulocytes [nTPM]":"31.6","Single Cell Type RNA - Granulosa cells [nTPM]":"36.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"28.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.4","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"124.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.1","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"37.7","Single Cell Type RNA - Langerhans cells [nTPM]":"22.3","Single Cell Type RNA - Late spermatids [nTPM]":"21.6","Single Cell Type RNA - Leydig cells [nTPM]":"19.6","Single Cell Type RNA - Macrophages [nTPM]":"33.4","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"63.7","Single Cell Type RNA - monocytes [nTPM]":"43.1","Single Cell Type RNA - Muller glia cells [nTPM]":"26.1","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"91.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.4","Single Cell Type RNA - Paneth cells [nTPM]":"22.0","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"23.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"58.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.0","Single Cell Type RNA - Spermatocytes [nTPM]":"173.0","Single Cell Type RNA - Spermatogonia [nTPM]":"14.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"56.5","Single Cell Type RNA - T-cells [nTPM]":"26.4","Single Cell Type RNA - Theca cells [nTPM]":"26.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.6","Single Cell Type RNA - Urothelial cells [nTPM]":"17.7"},{"Gene":"SOD1","Gene synonym":["ALS","ALS1","IPOA"],"Ensembl":"ENSG00000142168","Gene description":"Superoxide dismutase 1","Uniprot":["P00441"],"Chromosome":"21","Position":"31659666-31668931","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Antioxidant","Oxidoreductase"],"Disease involvement":["Amyotrophic lateral sclerosis","Cancer-related genes","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1645.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"3357.9","Proximal tubular cells":"3285.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001401","CAB008670"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":44900000,"Blood concentration - Conc. blood MS [pg\/L]":"50000000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB008670":"AB_1623312","HPA001401":"AB_1080132"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Tissue RNA - adipose tissue [nTPM]":"257.6","Tissue RNA - adrenal gland [nTPM]":"597.1","Tissue RNA - amygdala [nTPM]":"558.0","Tissue RNA - appendix [nTPM]":"118.4","Tissue RNA - basal ganglia [nTPM]":"577.4","Tissue RNA - bone marrow [nTPM]":"166.4","Tissue RNA - breast [nTPM]":"233.5","Tissue RNA - cerebellum [nTPM]":"605.2","Tissue RNA - cerebral cortex [nTPM]":"805.1","Tissue RNA - cervix [nTPM]":"206.6","Tissue RNA - choroid plexus [nTPM]":"586.6","Tissue RNA - colon [nTPM]":"251.0","Tissue RNA - duodenum [nTPM]":"360.3","Tissue RNA - endometrium 1 [nTPM]":"179.5","Tissue RNA - epididymis [nTPM]":"228.4","Tissue RNA - esophagus [nTPM]":"221.1","Tissue RNA - fallopian tube [nTPM]":"197.1","Tissue RNA - gallbladder [nTPM]":"206.0","Tissue RNA - heart muscle [nTPM]":"477.3","Tissue RNA - hippocampal formation [nTPM]":"575.1","Tissue RNA - hypothalamus [nTPM]":"619.9","Tissue RNA - kidney [nTPM]":"483.2","Tissue RNA - liver [nTPM]":"1645.6","Tissue RNA - lung [nTPM]":"153.9","Tissue RNA - lymph node [nTPM]":"169.6","Tissue RNA - medulla oblongata [nTPM]":"619.8","Tissue RNA - midbrain [nTPM]":"604.6","Tissue RNA - ovary [nTPM]":"302.1","Tissue RNA - pancreas [nTPM]":"117.1","Tissue RNA - parathyroid gland [nTPM]":"210.6","Tissue RNA - pituitary gland [nTPM]":"236.7","Tissue RNA - placenta [nTPM]":"155.8","Tissue RNA - pons [nTPM]":"653.1","Tissue RNA - prostate [nTPM]":"203.9","Tissue RNA - rectum [nTPM]":"180.5","Tissue RNA - retina [nTPM]":"248.6","Tissue RNA - salivary gland [nTPM]":"160.5","Tissue RNA - seminal vesicle [nTPM]":"204.2","Tissue RNA - skeletal muscle [nTPM]":"428.0","Tissue RNA - skin 1 [nTPM]":"152.1","Tissue RNA - small intestine [nTPM]":"266.7","Tissue RNA - smooth muscle [nTPM]":"136.6","Tissue RNA - spinal cord [nTPM]":"588.1","Tissue RNA - spleen [nTPM]":"147.5","Tissue RNA - stomach 1 [nTPM]":"210.4","Tissue RNA - testis [nTPM]":"132.1","Tissue RNA - thalamus [nTPM]":"585.8","Tissue RNA - thymus [nTPM]":"165.7","Tissue RNA - thyroid gland [nTPM]":"197.4","Tissue RNA - tongue [nTPM]":"355.9","Tissue RNA - tonsil [nTPM]":"151.7","Tissue RNA - urinary bladder [nTPM]":"232.1","Tissue RNA - vagina [nTPM]":"220.6","Tissue RNA - white matter [nTPM]":"634.7","Cell RNA - A-431 [nTPM]":"526.8","Cell RNA - A549 [nTPM]":"451.4","Cell RNA - AF22 [nTPM]":"309.2","Cell RNA - AN3-CA [nTPM]":"312.8","Cell RNA - ASC diff [nTPM]":"407.3","Cell RNA - ASC TERT1 [nTPM]":"282.1","Cell RNA - BEWO [nTPM]":"257.8","Cell RNA - BJ [nTPM]":"430.2","Cell RNA - BJ hTERT+ [nTPM]":"258.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"291.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"217.4","Cell RNA - CACO-2 [nTPM]":"593.6","Cell RNA - CAPAN-2 [nTPM]":"326.0","Cell RNA - Daudi [nTPM]":"628.2","Cell RNA - EFO-21 [nTPM]":"441.2","Cell RNA - fHDF\/TERT166 [nTPM]":"405.8","Cell RNA - GAMG [nTPM]":"517.7","Cell RNA - HaCaT [nTPM]":"186.1","Cell RNA - HAP1 [nTPM]":"453.3","Cell RNA - HBEC3-KT [nTPM]":"320.6","Cell RNA - HBF TERT88 [nTPM]":"239.9","Cell RNA - HDLM-2 [nTPM]":"463.3","Cell RNA - HEK 293 [nTPM]":"540.0","Cell RNA - HEL [nTPM]":"1008.2","Cell RNA - HeLa [nTPM]":"579.5","Cell RNA - Hep G2 [nTPM]":"866.3","Cell RNA - HHSteC [nTPM]":"267.4","Cell RNA - HL-60 [nTPM]":"451.7","Cell RNA - HMC-1 [nTPM]":"363.1","Cell RNA - HSkMC [nTPM]":"294.8","Cell RNA - hTCEpi [nTPM]":"240.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"406.5","Cell RNA - hTERT-HME1 [nTPM]":"225.2","Cell RNA - hTERT-RPE1 [nTPM]":"327.9","Cell RNA - HUVEC TERT2 [nTPM]":"331.2","Cell RNA - JURKAT [nTPM]":"469.0","Cell RNA - K-562 [nTPM]":"704.4","Cell RNA - Karpas-707 [nTPM]":"773.2","Cell RNA - LHCN-M2 [nTPM]":"357.4","Cell RNA - MCF7 [nTPM]":"860.0","Cell RNA - MOLT-4 [nTPM]":"489.0","Cell RNA - NB-4 [nTPM]":"454.5","Cell RNA - NTERA-2 [nTPM]":"466.1","Cell RNA - OE19 [nTPM]":"830.0","Cell RNA - PC-3 [nTPM]":"475.4","Cell RNA - REH [nTPM]":"413.0","Cell RNA - RH-30 [nTPM]":"622.0","Cell RNA - RPMI-8226 [nTPM]":"981.4","Cell RNA - RPTEC TERT1 [nTPM]":"579.4","Cell RNA - RT4 [nTPM]":"320.5","Cell RNA - SCLC-21H [nTPM]":"335.9","Cell RNA - SH-SY5Y [nTPM]":"281.4","Cell RNA - SiHa [nTPM]":"805.1","Cell RNA - SK-BR-3 [nTPM]":"419.4","Cell RNA - SK-MEL-30 [nTPM]":"438.3","Cell RNA - SuSa [nTPM]":"279.2","Cell RNA - T-47d [nTPM]":"484.3","Cell RNA - THP-1 [nTPM]":"393.4","Cell RNA - TIME [nTPM]":"387.4","Cell RNA - U-138 MG [nTPM]":"222.9","Cell RNA - U-2 OS [nTPM]":"489.2","Cell RNA - U-2197 [nTPM]":"304.7","Cell RNA - U-251 MG [nTPM]":"322.0","Cell RNA - U-266\/70 [nTPM]":"583.4","Cell RNA - U-266\/84 [nTPM]":"1374.2","Cell RNA - U-698 [nTPM]":"741.8","Cell RNA - U-87 MG [nTPM]":"455.7","Cell RNA - U-937 [nTPM]":"654.3","Cell RNA - WM-115 [nTPM]":"301.9","Blood RNA - basophil [nTPM]":"204.2","Blood RNA - classical monocyte [nTPM]":"159.7","Blood RNA - eosinophil [nTPM]":"194.0","Blood RNA - gdT-cell [nTPM]":"313.4","Blood RNA - intermediate monocyte [nTPM]":"234.0","Blood RNA - MAIT T-cell [nTPM]":"365.3","Blood RNA - memory B-cell [nTPM]":"427.1","Blood RNA - memory CD4 T-cell [nTPM]":"509.2","Blood RNA - memory CD8 T-cell [nTPM]":"402.4","Blood RNA - myeloid DC [nTPM]":"212.8","Blood RNA - naive B-cell [nTPM]":"310.1","Blood RNA - naive CD4 T-cell [nTPM]":"521.8","Blood RNA - naive CD8 T-cell [nTPM]":"412.1","Blood RNA - neutrophil [nTPM]":"37.8","Blood RNA - NK-cell [nTPM]":"241.4","Blood RNA - non-classical monocyte [nTPM]":"465.4","Blood RNA - plasmacytoid DC [nTPM]":"240.6","Blood RNA - T-reg [nTPM]":"746.0","Blood RNA - total PBMC [nTPM]":"474.5","Brain RNA - amygdala [nTPM]":"558.0","Brain RNA - basal ganglia [nTPM]":"577.4","Brain RNA - cerebellum [nTPM]":"605.2","Brain RNA - cerebral cortex [nTPM]":"805.1","Brain RNA - hippocampal formation [nTPM]":"575.1","Brain RNA - hypothalamus [nTPM]":"619.9","Brain RNA - medulla oblongata [nTPM]":"619.8","Brain RNA - midbrain [nTPM]":"604.6","Brain RNA - pons [nTPM]":"653.1","Brain RNA - spinal cord [nTPM]":"588.1","Brain RNA - thalamus [nTPM]":"585.8","Brain RNA - white matter [nTPM]":"634.7","Single Cell Type RNA - Adipocytes [nTPM]":"319.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"294.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"175.1","Single Cell Type RNA - Astrocytes [nTPM]":"38.2","Single Cell Type RNA - B-cells [nTPM]":"248.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"491.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"672.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"479.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"319.8","Single Cell Type RNA - Bipolar cells [nTPM]":"226.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"264.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"352.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"721.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"527.6","Single Cell Type RNA - Club cells [nTPM]":"294.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"391.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"703.4","Single Cell Type RNA - dendritic cells [nTPM]":"250.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"703.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1631.7","Single Cell Type RNA - Ductal cells [nTPM]":"426.3","Single Cell Type RNA - Early spermatids [nTPM]":"277.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"410.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"241.2","Single Cell Type RNA - Endothelial cells [nTPM]":"261.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"288.4","Single Cell Type RNA - Erythroid cells [nTPM]":"898.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"807.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"574.9","Single Cell Type RNA - Fibroblasts [nTPM]":"365.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"198.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"216.3","Single Cell Type RNA - granulocytes [nTPM]":"220.0","Single Cell Type RNA - Granulosa cells [nTPM]":"278.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"318.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3357.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"363.3","Single Cell Type RNA - Horizontal cells [nTPM]":"282.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"402.7","Single Cell Type RNA - Ionocytes [nTPM]":"366.2","Single Cell Type RNA - Kupffer cells [nTPM]":"220.0","Single Cell Type RNA - Langerhans cells [nTPM]":"318.5","Single Cell Type RNA - Late spermatids [nTPM]":"952.2","Single Cell Type RNA - Leydig cells [nTPM]":"521.9","Single Cell Type RNA - Macrophages [nTPM]":"224.2","Single Cell Type RNA - Melanocytes [nTPM]":"419.8","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"313.1","Single Cell Type RNA - Muller glia cells [nTPM]":"598.5","Single Cell Type RNA - NK-cells [nTPM]":"239.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"68.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"322.8","Single Cell Type RNA - Paneth cells [nTPM]":"600.9","Single Cell Type RNA - Peritubular cells [nTPM]":"528.1","Single Cell Type RNA - Plasma cells [nTPM]":"178.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"567.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1158.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3285.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"638.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"216.5","Single Cell Type RNA - Sertoli cells [nTPM]":"440.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"313.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"404.5","Single Cell Type RNA - Spermatocytes [nTPM]":"211.7","Single Cell Type RNA - Spermatogonia [nTPM]":"506.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"379.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"349.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"725.9","Single Cell Type RNA - T-cells [nTPM]":"423.1","Single Cell Type RNA - Theca cells [nTPM]":"470.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"593.6","Single Cell Type RNA - Urothelial cells [nTPM]":"497.7"},{"Gene":"SPART","Gene synonym":["KIAA0610","SPG20","TAHCCP1"],"Ensembl":"ENSG00000133104","Gene description":"Spartin","Uniprot":["Q8N0X7"],"Chromosome":"13","Position":"36301638-36370180","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"75.0","Proximal tubular cells":"90.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"172.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"172.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039053","HPA039054"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA039053":"AB_10672769","HPA039054":"AB_2676323"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"42.3","Tissue RNA - adrenal gland [nTPM]":"48.4","Tissue RNA - amygdala [nTPM]":"36.9","Tissue RNA - appendix [nTPM]":"18.0","Tissue RNA - basal ganglia [nTPM]":"42.8","Tissue RNA - bone marrow [nTPM]":"23.6","Tissue RNA - breast [nTPM]":"32.5","Tissue RNA - cerebellum [nTPM]":"43.4","Tissue RNA - cerebral cortex [nTPM]":"50.6","Tissue RNA - cervix [nTPM]":"49.2","Tissue RNA - choroid plexus [nTPM]":"42.3","Tissue RNA - colon [nTPM]":"37.8","Tissue RNA - duodenum [nTPM]":"12.7","Tissue RNA - endometrium 1 [nTPM]":"42.4","Tissue RNA - epididymis [nTPM]":"67.1","Tissue RNA - esophagus [nTPM]":"24.5","Tissue RNA - fallopian tube [nTPM]":"44.5","Tissue RNA - gallbladder [nTPM]":"37.4","Tissue RNA - heart muscle [nTPM]":"25.7","Tissue RNA - hippocampal formation [nTPM]":"35.3","Tissue RNA - hypothalamus [nTPM]":"39.4","Tissue RNA - kidney [nTPM]":"48.4","Tissue RNA - liver [nTPM]":"19.9","Tissue RNA - lung [nTPM]":"27.0","Tissue RNA - lymph node [nTPM]":"15.7","Tissue RNA - medulla oblongata [nTPM]":"42.4","Tissue RNA - midbrain [nTPM]":"40.5","Tissue RNA - ovary [nTPM]":"63.6","Tissue RNA - pancreas [nTPM]":"14.6","Tissue RNA - parathyroid gland [nTPM]":"29.5","Tissue RNA - pituitary gland [nTPM]":"29.6","Tissue RNA - placenta [nTPM]":"39.8","Tissue RNA - pons [nTPM]":"42.1","Tissue RNA - prostate [nTPM]":"34.7","Tissue RNA - rectum [nTPM]":"13.3","Tissue RNA - retina [nTPM]":"43.3","Tissue RNA - salivary gland [nTPM]":"17.3","Tissue RNA - seminal vesicle [nTPM]":"36.4","Tissue RNA - skeletal muscle [nTPM]":"33.5","Tissue RNA - skin 1 [nTPM]":"18.4","Tissue RNA - small intestine [nTPM]":"15.4","Tissue RNA - smooth muscle [nTPM]":"52.8","Tissue RNA - spinal cord [nTPM]":"41.2","Tissue RNA - spleen [nTPM]":"30.7","Tissue RNA - stomach 1 [nTPM]":"21.1","Tissue RNA - testis [nTPM]":"27.6","Tissue RNA - thalamus [nTPM]":"38.3","Tissue RNA - thymus [nTPM]":"16.7","Tissue RNA - thyroid gland [nTPM]":"35.6","Tissue RNA - tongue [nTPM]":"33.7","Tissue RNA - tonsil [nTPM]":"11.2","Tissue RNA - urinary bladder [nTPM]":"35.5","Tissue RNA - vagina [nTPM]":"29.9","Tissue RNA - white matter [nTPM]":"51.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"22.4","Cell RNA - AF22 [nTPM]":"59.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"127.9","Cell RNA - ASC TERT1 [nTPM]":"106.6","Cell RNA - BEWO [nTPM]":"42.4","Cell RNA - BJ [nTPM]":"54.1","Cell RNA - BJ hTERT+ [nTPM]":"81.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"53.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.8","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"32.9","Cell RNA - fHDF\/TERT166 [nTPM]":"65.9","Cell RNA - GAMG [nTPM]":"98.2","Cell RNA - HaCaT [nTPM]":"31.2","Cell RNA - HAP1 [nTPM]":"81.4","Cell RNA - HBEC3-KT [nTPM]":"38.0","Cell RNA - HBF TERT88 [nTPM]":"57.5","Cell RNA - HDLM-2 [nTPM]":"4.4","Cell RNA - HEK 293 [nTPM]":"46.9","Cell RNA - HEL [nTPM]":"69.4","Cell RNA - HeLa [nTPM]":"28.3","Cell RNA - Hep G2 [nTPM]":"14.6","Cell RNA - HHSteC [nTPM]":"128.0","Cell RNA - HL-60 [nTPM]":"72.8","Cell RNA - HMC-1 [nTPM]":"134.3","Cell RNA - HSkMC [nTPM]":"106.2","Cell RNA - hTCEpi [nTPM]":"59.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.4","Cell RNA - hTERT-HME1 [nTPM]":"61.9","Cell RNA - hTERT-RPE1 [nTPM]":"131.7","Cell RNA - HUVEC TERT2 [nTPM]":"79.6","Cell RNA - JURKAT [nTPM]":"18.7","Cell RNA - K-562 [nTPM]":"30.6","Cell RNA - Karpas-707 [nTPM]":"11.9","Cell RNA - LHCN-M2 [nTPM]":"97.5","Cell RNA - MCF7 [nTPM]":"5.2","Cell RNA - MOLT-4 [nTPM]":"21.7","Cell RNA - NB-4 [nTPM]":"120.8","Cell RNA - NTERA-2 [nTPM]":"30.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"99.4","Cell RNA - RPMI-8226 [nTPM]":"2.5","Cell RNA - RPTEC TERT1 [nTPM]":"62.5","Cell RNA - RT4 [nTPM]":"28.2","Cell RNA - SCLC-21H [nTPM]":"6.2","Cell RNA - SH-SY5Y [nTPM]":"14.5","Cell RNA - SiHa [nTPM]":"46.3","Cell RNA - SK-BR-3 [nTPM]":"18.3","Cell RNA - SK-MEL-30 [nTPM]":"58.9","Cell RNA - SuSa [nTPM]":"85.3","Cell RNA - T-47d [nTPM]":"10.5","Cell RNA - THP-1 [nTPM]":"84.7","Cell RNA - TIME [nTPM]":"66.8","Cell RNA - U-138 MG [nTPM]":"40.0","Cell RNA - U-2 OS [nTPM]":"20.1","Cell RNA - U-2197 [nTPM]":"55.9","Cell RNA - U-251 MG [nTPM]":"32.2","Cell RNA - U-266\/70 [nTPM]":"14.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"44.6","Cell RNA - U-937 [nTPM]":"61.8","Cell RNA - WM-115 [nTPM]":"71.0","Blood RNA - basophil [nTPM]":"172.7","Blood RNA - classical monocyte [nTPM]":"22.1","Blood RNA - eosinophil [nTPM]":"30.1","Blood RNA - gdT-cell [nTPM]":"13.5","Blood RNA - intermediate monocyte [nTPM]":"21.7","Blood RNA - MAIT T-cell [nTPM]":"13.1","Blood RNA - memory B-cell [nTPM]":"10.1","Blood RNA - memory CD4 T-cell [nTPM]":"18.6","Blood RNA - memory CD8 T-cell [nTPM]":"5.4","Blood RNA - myeloid DC [nTPM]":"15.7","Blood RNA - naive B-cell [nTPM]":"9.7","Blood RNA - naive CD4 T-cell [nTPM]":"24.5","Blood RNA - naive CD8 T-cell [nTPM]":"13.1","Blood RNA - neutrophil [nTPM]":"35.0","Blood RNA - NK-cell [nTPM]":"14.2","Blood RNA - non-classical monocyte [nTPM]":"23.8","Blood RNA - plasmacytoid DC [nTPM]":"19.3","Blood RNA - T-reg [nTPM]":"4.8","Blood RNA - total PBMC [nTPM]":"18.1","Brain RNA - amygdala [nTPM]":"36.9","Brain RNA - basal ganglia [nTPM]":"42.8","Brain RNA - cerebellum [nTPM]":"43.4","Brain RNA - cerebral cortex [nTPM]":"50.6","Brain RNA - hippocampal formation [nTPM]":"35.3","Brain RNA - hypothalamus [nTPM]":"39.4","Brain RNA - medulla oblongata [nTPM]":"42.4","Brain RNA - midbrain [nTPM]":"40.5","Brain RNA - pons [nTPM]":"42.1","Brain RNA - spinal cord [nTPM]":"41.2","Brain RNA - thalamus [nTPM]":"38.3","Brain RNA - white matter [nTPM]":"51.0","Single Cell Type RNA - Adipocytes [nTPM]":"43.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"40.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"52.7","Single Cell Type RNA - dendritic cells [nTPM]":"18.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"66.5","Single Cell Type RNA - Ductal cells [nTPM]":"26.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"62.6","Single Cell Type RNA - Endothelial cells [nTPM]":"15.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"59.7","Single Cell Type RNA - Fibroblasts [nTPM]":"39.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.1","Single Cell Type RNA - granulocytes [nTPM]":"58.0","Single Cell Type RNA - Granulosa cells [nTPM]":"75.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"24.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"24.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"90.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"65.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"64.3","Single Cell Type RNA - T-cells [nTPM]":"10.8","Single Cell Type RNA - Theca cells [nTPM]":"59.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SPAST","Gene synonym":["ADPSP","FSP2","KIAA1083","SPG4"],"Ensembl":"ENSG00000021574","Gene description":"Spastin","Uniprot":["Q9UBP0"],"Chromosome":"2","Position":"32063556-32157637","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Differentiation","Neurogenesis"],"Molecular function":["Allosteric enzyme","Developmental protein","Isomerase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"55.2","Oligodendrocyte precursor cells":"59.3","Oligodendrocytes":"62.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017311"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA017311":"AB_1857415"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.15e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"9.0","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"12.7","Tissue RNA - bone marrow [nTPM]":"9.9","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"10.8","Tissue RNA - cerebral cortex [nTPM]":"12.9","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"7.1","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"6.9","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"9.0","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"5.9","Tissue RNA - liver [nTPM]":"9.6","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"9.7","Tissue RNA - medulla oblongata [nTPM]":"10.8","Tissue RNA - midbrain [nTPM]":"11.2","Tissue RNA - ovary [nTPM]":"9.1","Tissue RNA - pancreas [nTPM]":"5.3","Tissue RNA - parathyroid gland [nTPM]":"6.2","Tissue RNA - pituitary gland [nTPM]":"4.4","Tissue RNA - placenta [nTPM]":"6.8","Tissue RNA - pons [nTPM]":"10.5","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"7.5","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"8.0","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"11.6","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"10.7","Tissue RNA - thymus [nTPM]":"14.1","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"10.0","Tissue RNA - tonsil [nTPM]":"9.2","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"13.9","Cell RNA - A-431 [nTPM]":"17.5","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"19.7","Cell RNA - AN3-CA [nTPM]":"19.5","Cell RNA - ASC diff [nTPM]":"12.0","Cell RNA - ASC TERT1 [nTPM]":"14.2","Cell RNA - BEWO [nTPM]":"17.8","Cell RNA - BJ [nTPM]":"9.4","Cell RNA - BJ hTERT+ [nTPM]":"13.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.6","Cell RNA - CACO-2 [nTPM]":"16.9","Cell RNA - CAPAN-2 [nTPM]":"14.8","Cell RNA - Daudi [nTPM]":"30.2","Cell RNA - EFO-21 [nTPM]":"8.5","Cell RNA - fHDF\/TERT166 [nTPM]":"13.1","Cell RNA - GAMG [nTPM]":"14.2","Cell RNA - HaCaT [nTPM]":"12.0","Cell RNA - HAP1 [nTPM]":"19.5","Cell RNA - HBEC3-KT [nTPM]":"9.6","Cell RNA - HBF TERT88 [nTPM]":"11.9","Cell RNA - HDLM-2 [nTPM]":"20.7","Cell RNA - HEK 293 [nTPM]":"11.8","Cell RNA - HEL [nTPM]":"33.3","Cell RNA - HeLa [nTPM]":"6.0","Cell RNA - Hep G2 [nTPM]":"20.5","Cell RNA - HHSteC [nTPM]":"11.0","Cell RNA - HL-60 [nTPM]":"23.2","Cell RNA - HMC-1 [nTPM]":"22.4","Cell RNA - HSkMC [nTPM]":"7.9","Cell RNA - hTCEpi [nTPM]":"12.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.4","Cell RNA - hTERT-HME1 [nTPM]":"11.6","Cell RNA - hTERT-RPE1 [nTPM]":"11.7","Cell RNA - HUVEC TERT2 [nTPM]":"21.5","Cell RNA - JURKAT [nTPM]":"9.6","Cell RNA - K-562 [nTPM]":"27.6","Cell RNA - Karpas-707 [nTPM]":"10.0","Cell RNA - LHCN-M2 [nTPM]":"10.7","Cell RNA - MCF7 [nTPM]":"7.4","Cell RNA - MOLT-4 [nTPM]":"37.8","Cell RNA - NB-4 [nTPM]":"19.4","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"19.2","Cell RNA - PC-3 [nTPM]":"7.1","Cell RNA - REH [nTPM]":"19.8","Cell RNA - RH-30 [nTPM]":"27.9","Cell RNA - RPMI-8226 [nTPM]":"19.5","Cell RNA - RPTEC TERT1 [nTPM]":"13.0","Cell RNA - RT4 [nTPM]":"10.7","Cell RNA - SCLC-21H [nTPM]":"27.9","Cell RNA - SH-SY5Y [nTPM]":"29.9","Cell RNA - SiHa [nTPM]":"16.0","Cell RNA - SK-BR-3 [nTPM]":"13.2","Cell RNA - SK-MEL-30 [nTPM]":"15.9","Cell RNA - SuSa [nTPM]":"16.0","Cell RNA - T-47d [nTPM]":"8.7","Cell RNA - THP-1 [nTPM]":"15.8","Cell RNA - TIME [nTPM]":"18.8","Cell RNA - U-138 MG [nTPM]":"10.6","Cell RNA - U-2 OS [nTPM]":"16.2","Cell RNA - U-2197 [nTPM]":"9.5","Cell RNA - U-251 MG [nTPM]":"11.1","Cell RNA - U-266\/70 [nTPM]":"14.7","Cell RNA - U-266\/84 [nTPM]":"29.7","Cell RNA - U-698 [nTPM]":"23.8","Cell RNA - U-87 MG [nTPM]":"11.6","Cell RNA - U-937 [nTPM]":"19.9","Cell RNA - WM-115 [nTPM]":"13.0","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"3.9","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"5.3","Blood RNA - NK-cell [nTPM]":"3.9","Blood RNA - non-classical monocyte [nTPM]":"3.8","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"4.2","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"9.0","Brain RNA - basal ganglia [nTPM]":"12.7","Brain RNA - cerebellum [nTPM]":"10.8","Brain RNA - cerebral cortex [nTPM]":"12.9","Brain RNA - hippocampal formation [nTPM]":"9.0","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"10.8","Brain RNA - midbrain [nTPM]":"11.2","Brain RNA - pons [nTPM]":"10.5","Brain RNA - spinal cord [nTPM]":"11.6","Brain RNA - thalamus [nTPM]":"10.7","Brain RNA - white matter [nTPM]":"13.9","Single Cell Type RNA - Adipocytes [nTPM]":"15.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"26.4","Single Cell Type RNA - B-cells [nTPM]":"12.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"15.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"7.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - dendritic cells [nTPM]":"21.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.8","Single Cell Type RNA - Endothelial cells [nTPM]":"11.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.7","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"16.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"12.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.5","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"17.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"21.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.9","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"59.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"12.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"16.7","Single Cell Type RNA - Spermatogonia [nTPM]":"21.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - T-cells [nTPM]":"13.3","Single Cell Type RNA - Theca cells [nTPM]":"10.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"7.2"},{"Gene":"SPATA5","Gene synonym":["AFG2","SPAF"],"Ensembl":"ENSG00000145375","Gene description":"Spermatogenesis associated 5","Uniprot":["Q8NB90"],"Chromosome":"4","Position":"122923070-123319433","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Chaperone","Developmental protein","Hydrolase"],"Disease involvement":["Deafness","Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"207.9","Inhibitory neurons":"59.0","Microglial cells":"104.0","Oligodendrocyte precursor cells":"79.9","Oligodendrocytes":"91.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036450","HPA036451"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036450":"AB_2675131","HPA036451":"AB_10670107"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"1.1","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"1.3","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"3.2","Cell RNA - AF22 [nTPM]":"2.9","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"2.4","Cell RNA - ASC TERT1 [nTPM]":"1.7","Cell RNA - BEWO [nTPM]":"1.9","Cell RNA - BJ [nTPM]":"4.0","Cell RNA - BJ hTERT+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.3","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"3.2","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"2.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"2.4","Cell RNA - HaCaT [nTPM]":"2.0","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"5.6","Cell RNA - HDLM-2 [nTPM]":"6.2","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"3.8","Cell RNA - HeLa [nTPM]":"5.7","Cell RNA - Hep G2 [nTPM]":"2.5","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"5.2","Cell RNA - HMC-1 [nTPM]":"4.0","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.8","Cell RNA - hTERT-HME1 [nTPM]":"3.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"3.4","Cell RNA - JURKAT [nTPM]":"2.4","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"6.2","Cell RNA - LHCN-M2 [nTPM]":"4.6","Cell RNA - MCF7 [nTPM]":"2.4","Cell RNA - MOLT-4 [nTPM]":"10.1","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"3.6","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"3.3","Cell RNA - RH-30 [nTPM]":"7.2","Cell RNA - RPMI-8226 [nTPM]":"2.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.9","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"4.8","Cell RNA - SH-SY5Y [nTPM]":"3.1","Cell RNA - SiHa [nTPM]":"3.2","Cell RNA - SK-BR-3 [nTPM]":"2.3","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"4.2","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"6.9","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"4.6","Cell RNA - U-251 MG [nTPM]":"4.2","Cell RNA - U-266\/70 [nTPM]":"3.9","Cell RNA - U-266\/84 [nTPM]":"5.0","Cell RNA - U-698 [nTPM]":"3.3","Cell RNA - U-87 MG [nTPM]":"3.3","Cell RNA - U-937 [nTPM]":"4.4","Cell RNA - WM-115 [nTPM]":"6.2","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.3","Single Cell Type RNA - Adipocytes [nTPM]":"10.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"34.6","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"7.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.1","Single Cell Type RNA - Early spermatids [nTPM]":"207.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.6","Single Cell Type RNA - Endothelial cells [nTPM]":"8.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"25.0","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"104.0","Single Cell Type RNA - monocytes [nTPM]":"1.8","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"79.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"91.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"10.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"14.7","Single Cell Type RNA - Spermatogonia [nTPM]":"10.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"9.9","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.0"},{"Gene":"SPATA7","Gene synonym":["HSD3","LCA3"],"Ensembl":"ENSG00000042317","Gene description":"Spermatogenesis associated 7","Uniprot":["Q9P0W8"],"Chromosome":"14","Position":"88384924-88470350","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Leber congenital amaurosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"57.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Early spermatids":"946.9","Late spermatids":"1152.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038082","HPA038083"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm","Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038082":"AB_10671738","HPA038083":"AB_10671519"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.16e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.50e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"6.0","Tissue RNA - cerebellum [nTPM]":"28.4","Tissue RNA - cerebral cortex [nTPM]":"9.5","Tissue RNA - cervix [nTPM]":"7.2","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"5.8","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"6.6","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"8.3","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"8.6","Tissue RNA - hypothalamus [nTPM]":"10.4","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"5.1","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"7.9","Tissue RNA - parathyroid gland [nTPM]":"7.6","Tissue RNA - pituitary gland [nTPM]":"11.1","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"3.1","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"4.1","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"5.6","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"8.9","Tissue RNA - spleen [nTPM]":"3.6","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"57.0","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"12.1","Tissue RNA - tongue [nTPM]":"4.5","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"11.2","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"3.7","Cell RNA - AF22 [nTPM]":"5.5","Cell RNA - AN3-CA [nTPM]":"7.5","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"16.5","Cell RNA - BEWO [nTPM]":"6.0","Cell RNA - BJ [nTPM]":"5.2","Cell RNA - BJ hTERT+ [nTPM]":"9.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.4","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"4.5","Cell RNA - Daudi [nTPM]":"2.2","Cell RNA - EFO-21 [nTPM]":"2.5","Cell RNA - fHDF\/TERT166 [nTPM]":"5.7","Cell RNA - GAMG [nTPM]":"3.8","Cell RNA - HaCaT [nTPM]":"2.3","Cell RNA - HAP1 [nTPM]":"2.5","Cell RNA - HBEC3-KT [nTPM]":"4.0","Cell RNA - HBF TERT88 [nTPM]":"4.8","Cell RNA - HDLM-2 [nTPM]":"3.2","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"12.7","Cell RNA - HL-60 [nTPM]":"3.9","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"7.8","Cell RNA - hTCEpi [nTPM]":"6.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.1","Cell RNA - hTERT-HME1 [nTPM]":"3.9","Cell RNA - hTERT-RPE1 [nTPM]":"16.8","Cell RNA - HUVEC TERT2 [nTPM]":"9.4","Cell RNA - JURKAT [nTPM]":"5.0","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"2.7","Cell RNA - LHCN-M2 [nTPM]":"4.8","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"2.8","Cell RNA - NB-4 [nTPM]":"3.7","Cell RNA - NTERA-2 [nTPM]":"1.4","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"4.6","Cell RNA - REH [nTPM]":"3.9","Cell RNA - RH-30 [nTPM]":"5.6","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"8.1","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"5.1","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"5.0","Cell RNA - SuSa [nTPM]":"6.5","Cell RNA - T-47d [nTPM]":"6.0","Cell RNA - THP-1 [nTPM]":"4.2","Cell RNA - TIME [nTPM]":"4.9","Cell RNA - U-138 MG [nTPM]":"3.7","Cell RNA - U-2 OS [nTPM]":"4.0","Cell RNA - U-2197 [nTPM]":"5.2","Cell RNA - U-251 MG [nTPM]":"2.9","Cell RNA - U-266\/70 [nTPM]":"2.6","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"1.3","Cell RNA - U-87 MG [nTPM]":"6.2","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"2.1","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"28.4","Brain RNA - cerebral cortex [nTPM]":"9.5","Brain RNA - hippocampal formation [nTPM]":"8.6","Brain RNA - hypothalamus [nTPM]":"10.4","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"8.9","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"11.2","Single Cell Type RNA - Adipocytes [nTPM]":"7.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.3","Single Cell Type RNA - Astrocytes [nTPM]":"38.5","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"10.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"8.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"11.0","Single Cell Type RNA - Early spermatids [nTPM]":"946.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.2","Single Cell Type RNA - Endothelial cells [nTPM]":"6.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"113.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"11.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"19.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"4.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.7","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"91.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"1152.6","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"6.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"4.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"54.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.6","Single Cell Type RNA - Paneth cells [nTPM]":"4.3","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.9","Single Cell Type RNA - Spermatocytes [nTPM]":"37.5","Single Cell Type RNA - Spermatogonia [nTPM]":"14.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"20.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.5","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"SPG11","Gene synonym":["ALS5","FLJ21439","KIAA1840"],"Ensembl":"ENSG00000104133","Gene description":"SPG11 vesicle trafficking associated, spatacsin","Uniprot":["Q96JI7"],"Chromosome":"15","Position":"44562696-44663678","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Charcot-Marie-Tooth disease","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"121.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040412","HPA040947"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA040412":"AB_10795418","HPA040947":"AB_10796232"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.28e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.1","Tissue RNA - adrenal gland [nTPM]":"27.1","Tissue RNA - amygdala [nTPM]":"18.4","Tissue RNA - appendix [nTPM]":"18.2","Tissue RNA - basal ganglia [nTPM]":"25.7","Tissue RNA - bone marrow [nTPM]":"27.4","Tissue RNA - breast [nTPM]":"21.6","Tissue RNA - cerebellum [nTPM]":"24.4","Tissue RNA - cerebral cortex [nTPM]":"21.3","Tissue RNA - cervix [nTPM]":"21.5","Tissue RNA - choroid plexus [nTPM]":"23.9","Tissue RNA - colon [nTPM]":"25.6","Tissue RNA - duodenum [nTPM]":"17.1","Tissue RNA - endometrium 1 [nTPM]":"17.9","Tissue RNA - epididymis [nTPM]":"25.3","Tissue RNA - esophagus [nTPM]":"25.6","Tissue RNA - fallopian tube [nTPM]":"20.2","Tissue RNA - gallbladder [nTPM]":"16.1","Tissue RNA - heart muscle [nTPM]":"25.5","Tissue RNA - hippocampal formation [nTPM]":"17.5","Tissue RNA - hypothalamus [nTPM]":"22.2","Tissue RNA - kidney [nTPM]":"25.0","Tissue RNA - liver [nTPM]":"29.8","Tissue RNA - lung [nTPM]":"24.8","Tissue RNA - lymph node [nTPM]":"28.4","Tissue RNA - medulla oblongata [nTPM]":"23.8","Tissue RNA - midbrain [nTPM]":"22.1","Tissue RNA - ovary [nTPM]":"21.4","Tissue RNA - pancreas [nTPM]":"28.6","Tissue RNA - parathyroid gland [nTPM]":"26.7","Tissue RNA - pituitary gland [nTPM]":"21.3","Tissue RNA - placenta [nTPM]":"14.9","Tissue RNA - pons [nTPM]":"23.9","Tissue RNA - prostate [nTPM]":"25.3","Tissue RNA - rectum [nTPM]":"19.9","Tissue RNA - retina [nTPM]":"30.5","Tissue RNA - salivary gland [nTPM]":"24.7","Tissue RNA - seminal vesicle [nTPM]":"15.0","Tissue RNA - skeletal muscle [nTPM]":"22.9","Tissue RNA - skin 1 [nTPM]":"30.4","Tissue RNA - small intestine [nTPM]":"30.1","Tissue RNA - smooth muscle [nTPM]":"12.7","Tissue RNA - spinal cord [nTPM]":"19.1","Tissue RNA - spleen [nTPM]":"43.0","Tissue RNA - stomach 1 [nTPM]":"26.0","Tissue RNA - testis [nTPM]":"25.5","Tissue RNA - thalamus [nTPM]":"24.6","Tissue RNA - thymus [nTPM]":"23.7","Tissue RNA - thyroid gland [nTPM]":"30.9","Tissue RNA - tongue [nTPM]":"14.3","Tissue RNA - tonsil [nTPM]":"18.6","Tissue RNA - urinary bladder [nTPM]":"23.8","Tissue RNA - vagina [nTPM]":"22.6","Tissue RNA - white matter [nTPM]":"33.4","Cell RNA - A-431 [nTPM]":"13.2","Cell RNA - A549 [nTPM]":"8.8","Cell RNA - AF22 [nTPM]":"21.9","Cell RNA - AN3-CA [nTPM]":"21.6","Cell RNA - ASC diff [nTPM]":"33.7","Cell RNA - ASC TERT1 [nTPM]":"33.0","Cell RNA - BEWO [nTPM]":"15.8","Cell RNA - BJ [nTPM]":"13.4","Cell RNA - BJ hTERT+ [nTPM]":"17.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.6","Cell RNA - CACO-2 [nTPM]":"10.8","Cell RNA - CAPAN-2 [nTPM]":"12.5","Cell RNA - Daudi [nTPM]":"9.7","Cell RNA - EFO-21 [nTPM]":"16.5","Cell RNA - fHDF\/TERT166 [nTPM]":"18.2","Cell RNA - GAMG [nTPM]":"22.5","Cell RNA - HaCaT [nTPM]":"29.0","Cell RNA - HAP1 [nTPM]":"15.1","Cell RNA - HBEC3-KT [nTPM]":"20.8","Cell RNA - HBF TERT88 [nTPM]":"12.5","Cell RNA - HDLM-2 [nTPM]":"29.3","Cell RNA - HEK 293 [nTPM]":"9.0","Cell RNA - HEL [nTPM]":"22.1","Cell RNA - HeLa [nTPM]":"21.1","Cell RNA - Hep G2 [nTPM]":"16.4","Cell RNA - HHSteC [nTPM]":"23.7","Cell RNA - HL-60 [nTPM]":"22.2","Cell RNA - HMC-1 [nTPM]":"19.2","Cell RNA - HSkMC [nTPM]":"25.3","Cell RNA - hTCEpi [nTPM]":"23.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.7","Cell RNA - hTERT-HME1 [nTPM]":"30.5","Cell RNA - hTERT-RPE1 [nTPM]":"20.4","Cell RNA - HUVEC TERT2 [nTPM]":"18.6","Cell RNA - JURKAT [nTPM]":"16.6","Cell RNA - K-562 [nTPM]":"28.8","Cell RNA - Karpas-707 [nTPM]":"24.2","Cell RNA - LHCN-M2 [nTPM]":"18.6","Cell RNA - MCF7 [nTPM]":"11.5","Cell RNA - MOLT-4 [nTPM]":"10.1","Cell RNA - NB-4 [nTPM]":"19.7","Cell RNA - NTERA-2 [nTPM]":"11.5","Cell RNA - OE19 [nTPM]":"40.3","Cell RNA - PC-3 [nTPM]":"11.6","Cell RNA - REH [nTPM]":"12.9","Cell RNA - RH-30 [nTPM]":"18.5","Cell RNA - RPMI-8226 [nTPM]":"10.6","Cell RNA - RPTEC TERT1 [nTPM]":"28.0","Cell RNA - RT4 [nTPM]":"33.6","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"16.8","Cell RNA - SiHa [nTPM]":"14.6","Cell RNA - SK-BR-3 [nTPM]":"23.3","Cell RNA - SK-MEL-30 [nTPM]":"13.1","Cell RNA - SuSa [nTPM]":"18.0","Cell RNA - T-47d [nTPM]":"22.0","Cell RNA - THP-1 [nTPM]":"30.2","Cell RNA - TIME [nTPM]":"19.9","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"8.5","Cell RNA - U-2197 [nTPM]":"21.4","Cell RNA - U-251 MG [nTPM]":"16.5","Cell RNA - U-266\/70 [nTPM]":"23.8","Cell RNA - U-266\/84 [nTPM]":"22.6","Cell RNA - U-698 [nTPM]":"19.2","Cell RNA - U-87 MG [nTPM]":"17.6","Cell RNA - U-937 [nTPM]":"28.8","Cell RNA - WM-115 [nTPM]":"17.9","Blood RNA - basophil [nTPM]":"5.7","Blood RNA - classical monocyte [nTPM]":"7.7","Blood RNA - eosinophil [nTPM]":"11.8","Blood RNA - gdT-cell [nTPM]":"6.5","Blood RNA - intermediate monocyte [nTPM]":"9.2","Blood RNA - MAIT T-cell [nTPM]":"6.9","Blood RNA - memory B-cell [nTPM]":"10.0","Blood RNA - memory CD4 T-cell [nTPM]":"5.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"6.2","Blood RNA - naive B-cell [nTPM]":"11.3","Blood RNA - naive CD4 T-cell [nTPM]":"4.3","Blood RNA - naive CD8 T-cell [nTPM]":"5.3","Blood RNA - neutrophil [nTPM]":"11.6","Blood RNA - NK-cell [nTPM]":"6.2","Blood RNA - non-classical monocyte [nTPM]":"12.4","Blood RNA - plasmacytoid DC [nTPM]":"6.3","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"3.7","Brain RNA - amygdala [nTPM]":"18.4","Brain RNA - basal ganglia [nTPM]":"25.7","Brain RNA - cerebellum [nTPM]":"24.4","Brain RNA - cerebral cortex [nTPM]":"21.3","Brain RNA - hippocampal formation [nTPM]":"17.5","Brain RNA - hypothalamus [nTPM]":"22.2","Brain RNA - medulla oblongata [nTPM]":"23.8","Brain RNA - midbrain [nTPM]":"22.1","Brain RNA - pons [nTPM]":"23.9","Brain RNA - spinal cord [nTPM]":"19.1","Brain RNA - thalamus [nTPM]":"24.6","Brain RNA - white matter [nTPM]":"33.4","Single Cell Type RNA - Adipocytes [nTPM]":"21.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.2","Single Cell Type RNA - Astrocytes [nTPM]":"56.2","Single Cell Type RNA - B-cells [nTPM]":"40.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"25.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"31.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.5","Single Cell Type RNA - dendritic cells [nTPM]":"30.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"21.3","Single Cell Type RNA - Early spermatids [nTPM]":"28.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.2","Single Cell Type RNA - Endothelial cells [nTPM]":"17.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.0","Single Cell Type RNA - Erythroid cells [nTPM]":"22.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"62.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.1","Single Cell Type RNA - Fibroblasts [nTPM]":"19.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.6","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"31.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"23.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"68.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.2","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"43.3","Single Cell Type RNA - Langerhans cells [nTPM]":"23.5","Single Cell Type RNA - Late spermatids [nTPM]":"33.2","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"40.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"74.9","Single Cell Type RNA - monocytes [nTPM]":"88.1","Single Cell Type RNA - Muller glia cells [nTPM]":"14.0","Single Cell Type RNA - NK-cells [nTPM]":"50.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"68.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"121.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.7","Single Cell Type RNA - Paneth cells [nTPM]":"24.0","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"21.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.3","Single Cell Type RNA - Spermatocytes [nTPM]":"51.7","Single Cell Type RNA - Spermatogonia [nTPM]":"31.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"29.5","Single Cell Type RNA - Theca cells [nTPM]":"24.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.3","Single Cell Type RNA - Urothelial cells [nTPM]":"22.2"},{"Gene":"SPG21","Gene synonym":["ABHD21","ACP33","BM-019","GL010","MAST"],"Ensembl":"ENSG00000090487","Gene description":"SPG21 abhydrolase domain containing, maspardin","Uniprot":["Q9NZD8"],"Chromosome":"15","Position":"64963022-64990310","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"181.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040407","HPA040436"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040407":"AB_2676965","HPA040436":"AB_10796454"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Tissue RNA - adipose tissue [nTPM]":"56.6","Tissue RNA - adrenal gland [nTPM]":"61.7","Tissue RNA - amygdala [nTPM]":"48.4","Tissue RNA - appendix [nTPM]":"50.8","Tissue RNA - basal ganglia [nTPM]":"54.1","Tissue RNA - bone marrow [nTPM]":"69.4","Tissue RNA - breast [nTPM]":"68.8","Tissue RNA - cerebellum [nTPM]":"51.5","Tissue RNA - cerebral cortex [nTPM]":"52.9","Tissue RNA - cervix [nTPM]":"60.4","Tissue RNA - choroid plexus [nTPM]":"66.0","Tissue RNA - colon [nTPM]":"61.6","Tissue RNA - duodenum [nTPM]":"52.1","Tissue RNA - endometrium 1 [nTPM]":"60.2","Tissue RNA - epididymis [nTPM]":"150.1","Tissue RNA - esophagus [nTPM]":"46.1","Tissue RNA - fallopian tube [nTPM]":"73.4","Tissue RNA - gallbladder [nTPM]":"54.7","Tissue RNA - heart muscle [nTPM]":"54.4","Tissue RNA - hippocampal formation [nTPM]":"47.8","Tissue RNA - hypothalamus [nTPM]":"50.3","Tissue RNA - kidney [nTPM]":"85.3","Tissue RNA - liver [nTPM]":"113.1","Tissue RNA - lung [nTPM]":"61.9","Tissue RNA - lymph node [nTPM]":"56.9","Tissue RNA - medulla oblongata [nTPM]":"52.1","Tissue RNA - midbrain [nTPM]":"50.2","Tissue RNA - ovary [nTPM]":"55.3","Tissue RNA - pancreas [nTPM]":"54.7","Tissue RNA - parathyroid gland [nTPM]":"72.1","Tissue RNA - pituitary gland [nTPM]":"47.1","Tissue RNA - placenta [nTPM]":"66.3","Tissue RNA - pons [nTPM]":"52.7","Tissue RNA - prostate [nTPM]":"49.8","Tissue RNA - rectum [nTPM]":"59.3","Tissue RNA - retina [nTPM]":"38.6","Tissue RNA - salivary gland [nTPM]":"45.7","Tissue RNA - seminal vesicle [nTPM]":"59.0","Tissue RNA - skeletal muscle [nTPM]":"74.3","Tissue RNA - skin 1 [nTPM]":"58.5","Tissue RNA - small intestine [nTPM]":"46.6","Tissue RNA - smooth muscle [nTPM]":"64.5","Tissue RNA - spinal cord [nTPM]":"51.1","Tissue RNA - spleen [nTPM]":"52.6","Tissue RNA - stomach 1 [nTPM]":"60.1","Tissue RNA - testis [nTPM]":"35.0","Tissue RNA - thalamus [nTPM]":"52.6","Tissue RNA - thymus [nTPM]":"57.7","Tissue RNA - thyroid gland [nTPM]":"83.1","Tissue RNA - tongue [nTPM]":"42.4","Tissue RNA - tonsil [nTPM]":"58.8","Tissue RNA - urinary bladder [nTPM]":"61.2","Tissue RNA - vagina [nTPM]":"47.8","Tissue RNA - white matter [nTPM]":"59.4","Cell RNA - A-431 [nTPM]":"87.0","Cell RNA - A549 [nTPM]":"127.0","Cell RNA - AF22 [nTPM]":"62.8","Cell RNA - AN3-CA [nTPM]":"119.5","Cell RNA - ASC diff [nTPM]":"158.7","Cell RNA - ASC TERT1 [nTPM]":"155.7","Cell RNA - BEWO [nTPM]":"78.0","Cell RNA - BJ [nTPM]":"52.8","Cell RNA - BJ hTERT+ [nTPM]":"179.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"103.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"119.8","Cell RNA - CACO-2 [nTPM]":"57.4","Cell RNA - CAPAN-2 [nTPM]":"131.1","Cell RNA - Daudi [nTPM]":"99.1","Cell RNA - EFO-21 [nTPM]":"80.6","Cell RNA - fHDF\/TERT166 [nTPM]":"124.8","Cell RNA - GAMG [nTPM]":"153.1","Cell RNA - HaCaT [nTPM]":"113.3","Cell RNA - HAP1 [nTPM]":"182.1","Cell RNA - HBEC3-KT [nTPM]":"124.5","Cell RNA - HBF TERT88 [nTPM]":"97.8","Cell RNA - HDLM-2 [nTPM]":"41.0","Cell RNA - HEK 293 [nTPM]":"58.5","Cell RNA - HEL [nTPM]":"85.7","Cell RNA - HeLa [nTPM]":"81.7","Cell RNA - Hep G2 [nTPM]":"104.0","Cell RNA - HHSteC [nTPM]":"200.7","Cell RNA - HL-60 [nTPM]":"82.2","Cell RNA - HMC-1 [nTPM]":"72.7","Cell RNA - HSkMC [nTPM]":"107.0","Cell RNA - hTCEpi [nTPM]":"139.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"82.1","Cell RNA - hTERT-HME1 [nTPM]":"154.2","Cell RNA - hTERT-RPE1 [nTPM]":"100.7","Cell RNA - HUVEC TERT2 [nTPM]":"125.6","Cell RNA - JURKAT [nTPM]":"112.2","Cell RNA - K-562 [nTPM]":"72.7","Cell RNA - Karpas-707 [nTPM]":"78.3","Cell RNA - LHCN-M2 [nTPM]":"127.8","Cell RNA - MCF7 [nTPM]":"124.1","Cell RNA - MOLT-4 [nTPM]":"75.8","Cell RNA - NB-4 [nTPM]":"71.5","Cell RNA - NTERA-2 [nTPM]":"69.6","Cell RNA - OE19 [nTPM]":"193.9","Cell RNA - PC-3 [nTPM]":"66.3","Cell RNA - REH [nTPM]":"78.2","Cell RNA - RH-30 [nTPM]":"67.3","Cell RNA - RPMI-8226 [nTPM]":"174.6","Cell RNA - RPTEC TERT1 [nTPM]":"107.1","Cell RNA - RT4 [nTPM]":"103.6","Cell RNA - SCLC-21H [nTPM]":"76.7","Cell RNA - SH-SY5Y [nTPM]":"68.6","Cell RNA - SiHa [nTPM]":"62.7","Cell RNA - SK-BR-3 [nTPM]":"131.4","Cell RNA - SK-MEL-30 [nTPM]":"124.9","Cell RNA - SuSa [nTPM]":"123.3","Cell RNA - T-47d [nTPM]":"89.9","Cell RNA - THP-1 [nTPM]":"140.9","Cell RNA - TIME [nTPM]":"61.5","Cell RNA - U-138 MG [nTPM]":"87.1","Cell RNA - U-2 OS [nTPM]":"90.6","Cell RNA - U-2197 [nTPM]":"125.4","Cell RNA - U-251 MG [nTPM]":"80.6","Cell RNA - U-266\/70 [nTPM]":"55.6","Cell RNA - U-266\/84 [nTPM]":"101.8","Cell RNA - U-698 [nTPM]":"58.2","Cell RNA - U-87 MG [nTPM]":"112.8","Cell RNA - U-937 [nTPM]":"215.1","Cell RNA - WM-115 [nTPM]":"75.1","Blood RNA - basophil [nTPM]":"9.9","Blood RNA - classical monocyte [nTPM]":"138.2","Blood RNA - eosinophil [nTPM]":"15.5","Blood RNA - gdT-cell [nTPM]":"14.1","Blood RNA - intermediate monocyte [nTPM]":"84.2","Blood RNA - MAIT T-cell [nTPM]":"13.1","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"13.8","Blood RNA - memory CD8 T-cell [nTPM]":"14.7","Blood RNA - myeloid DC [nTPM]":"76.9","Blood RNA - naive B-cell [nTPM]":"37.6","Blood RNA - naive CD4 T-cell [nTPM]":"19.9","Blood RNA - naive CD8 T-cell [nTPM]":"10.9","Blood RNA - neutrophil [nTPM]":"181.4","Blood RNA - NK-cell [nTPM]":"15.7","Blood RNA - non-classical monocyte [nTPM]":"69.8","Blood RNA - plasmacytoid DC [nTPM]":"25.1","Blood RNA - T-reg [nTPM]":"17.5","Blood RNA - total PBMC [nTPM]":"52.3","Brain RNA - amygdala [nTPM]":"48.4","Brain RNA - basal ganglia [nTPM]":"54.1","Brain RNA - cerebellum [nTPM]":"51.5","Brain RNA - cerebral cortex [nTPM]":"52.9","Brain RNA - hippocampal formation [nTPM]":"47.8","Brain RNA - hypothalamus [nTPM]":"50.3","Brain RNA - medulla oblongata [nTPM]":"52.1","Brain RNA - midbrain [nTPM]":"50.2","Brain RNA - pons [nTPM]":"52.7","Brain RNA - spinal cord [nTPM]":"51.1","Brain RNA - thalamus [nTPM]":"52.6","Brain RNA - white matter [nTPM]":"59.4","Single Cell Type RNA - Adipocytes [nTPM]":"29.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.3","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"67.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"74.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"81.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"70.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"66.6","Single Cell Type RNA - Bipolar cells [nTPM]":"16.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"62.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"32.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"51.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"202.9","Single Cell Type RNA - dendritic cells [nTPM]":"33.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"137.0","Single Cell Type RNA - Ductal cells [nTPM]":"97.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.9","Single Cell Type RNA - Endothelial cells [nTPM]":"56.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"64.8","Single Cell Type RNA - Erythroid cells [nTPM]":"54.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"74.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"92.2","Single Cell Type RNA - Fibroblasts [nTPM]":"67.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.3","Single Cell Type RNA - granulocytes [nTPM]":"28.5","Single Cell Type RNA - Granulosa cells [nTPM]":"37.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"38.2","Single Cell Type RNA - Hepatocytes [nTPM]":"121.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"153.9","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"58.2","Single Cell Type RNA - Ionocytes [nTPM]":"61.1","Single Cell Type RNA - Kupffer cells [nTPM]":"158.7","Single Cell Type RNA - Langerhans cells [nTPM]":"145.4","Single Cell Type RNA - Late spermatids [nTPM]":"13.2","Single Cell Type RNA - Leydig cells [nTPM]":"86.6","Single Cell Type RNA - Macrophages [nTPM]":"128.5","Single Cell Type RNA - Melanocytes [nTPM]":"80.0","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"123.2","Single Cell Type RNA - Muller glia cells [nTPM]":"24.8","Single Cell Type RNA - NK-cells [nTPM]":"64.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"62.3","Single Cell Type RNA - Paneth cells [nTPM]":"93.5","Single Cell Type RNA - Peritubular cells [nTPM]":"89.9","Single Cell Type RNA - Plasma cells [nTPM]":"66.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"145.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"121.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"202.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"57.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.9","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"93.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"39.5","Single Cell Type RNA - Spermatocytes [nTPM]":"35.4","Single Cell Type RNA - Spermatogonia [nTPM]":"51.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"75.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"82.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"186.5","Single Cell Type RNA - T-cells [nTPM]":"46.5","Single Cell Type RNA - Theca cells [nTPM]":"35.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"69.5","Single Cell Type RNA - Urothelial cells [nTPM]":"123.5"},{"Gene":"SPG7","Gene synonym":["CAR","CMAR","SPG5C"],"Ensembl":"ENSG00000197912","Gene description":"SPG7 matrix AAA peptidase subunit, paraplegin","Uniprot":["Q9UQ90"],"Chromosome":"16","Position":"89490719-89557766","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.91e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.25e-4"},"Tissue RNA - adipose tissue [nTPM]":"29.8","Tissue RNA - adrenal gland [nTPM]":"44.8","Tissue RNA - amygdala [nTPM]":"19.3","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"18.8","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"27.9","Tissue RNA - cerebellum [nTPM]":"21.3","Tissue RNA - cerebral cortex [nTPM]":"28.6","Tissue RNA - cervix [nTPM]":"31.5","Tissue RNA - choroid plexus [nTPM]":"18.5","Tissue RNA - colon [nTPM]":"33.3","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"31.8","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"28.2","Tissue RNA - fallopian tube [nTPM]":"26.4","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"52.3","Tissue RNA - hippocampal formation [nTPM]":"19.4","Tissue RNA - hypothalamus [nTPM]":"18.3","Tissue RNA - kidney [nTPM]":"32.4","Tissue RNA - liver [nTPM]":"47.0","Tissue RNA - lung [nTPM]":"24.9","Tissue RNA - lymph node [nTPM]":"8.9","Tissue RNA - medulla oblongata [nTPM]":"19.7","Tissue RNA - midbrain [nTPM]":"18.6","Tissue RNA - ovary [nTPM]":"39.0","Tissue RNA - pancreas [nTPM]":"31.9","Tissue RNA - parathyroid gland [nTPM]":"13.8","Tissue RNA - pituitary gland [nTPM]":"38.7","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"20.3","Tissue RNA - prostate [nTPM]":"31.2","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"9.9","Tissue RNA - salivary gland [nTPM]":"29.0","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"56.7","Tissue RNA - skin 1 [nTPM]":"31.3","Tissue RNA - small intestine [nTPM]":"35.5","Tissue RNA - smooth muscle [nTPM]":"9.0","Tissue RNA - spinal cord [nTPM]":"16.9","Tissue RNA - spleen [nTPM]":"34.1","Tissue RNA - stomach 1 [nTPM]":"31.1","Tissue RNA - testis [nTPM]":"31.9","Tissue RNA - thalamus [nTPM]":"18.7","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"53.1","Tissue RNA - tongue [nTPM]":"31.0","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"30.1","Tissue RNA - vagina [nTPM]":"26.9","Tissue RNA - white matter [nTPM]":"20.0","Cell RNA - A-431 [nTPM]":"11.5","Cell RNA - A549 [nTPM]":"28.3","Cell RNA - AF22 [nTPM]":"17.3","Cell RNA - AN3-CA [nTPM]":"26.6","Cell RNA - ASC diff [nTPM]":"33.2","Cell RNA - ASC TERT1 [nTPM]":"24.2","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"27.3","Cell RNA - BJ hTERT+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.4","Cell RNA - CACO-2 [nTPM]":"23.0","Cell RNA - CAPAN-2 [nTPM]":"22.3","Cell RNA - Daudi [nTPM]":"16.5","Cell RNA - EFO-21 [nTPM]":"32.5","Cell RNA - fHDF\/TERT166 [nTPM]":"20.1","Cell RNA - GAMG [nTPM]":"16.2","Cell RNA - HaCaT [nTPM]":"30.5","Cell RNA - HAP1 [nTPM]":"21.5","Cell RNA - HBEC3-KT [nTPM]":"24.4","Cell RNA - HBF TERT88 [nTPM]":"14.7","Cell RNA - HDLM-2 [nTPM]":"11.7","Cell RNA - HEK 293 [nTPM]":"25.3","Cell RNA - HEL [nTPM]":"11.4","Cell RNA - HeLa [nTPM]":"12.0","Cell RNA - Hep G2 [nTPM]":"43.4","Cell RNA - HHSteC [nTPM]":"16.2","Cell RNA - HL-60 [nTPM]":"5.5","Cell RNA - HMC-1 [nTPM]":"10.3","Cell RNA - HSkMC [nTPM]":"15.2","Cell RNA - hTCEpi [nTPM]":"20.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.8","Cell RNA - hTERT-HME1 [nTPM]":"14.1","Cell RNA - hTERT-RPE1 [nTPM]":"27.9","Cell RNA - HUVEC TERT2 [nTPM]":"25.6","Cell RNA - JURKAT [nTPM]":"22.0","Cell RNA - K-562 [nTPM]":"23.1","Cell RNA - Karpas-707 [nTPM]":"5.5","Cell RNA - LHCN-M2 [nTPM]":"21.7","Cell RNA - MCF7 [nTPM]":"21.0","Cell RNA - MOLT-4 [nTPM]":"14.4","Cell RNA - NB-4 [nTPM]":"22.5","Cell RNA - NTERA-2 [nTPM]":"21.9","Cell RNA - OE19 [nTPM]":"23.8","Cell RNA - PC-3 [nTPM]":"21.4","Cell RNA - REH [nTPM]":"31.8","Cell RNA - RH-30 [nTPM]":"26.2","Cell RNA - RPMI-8226 [nTPM]":"10.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.9","Cell RNA - RT4 [nTPM]":"17.3","Cell RNA - SCLC-21H [nTPM]":"16.4","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"44.9","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"9.5","Cell RNA - SuSa [nTPM]":"15.2","Cell RNA - T-47d [nTPM]":"22.6","Cell RNA - THP-1 [nTPM]":"17.0","Cell RNA - TIME [nTPM]":"33.7","Cell RNA - U-138 MG [nTPM]":"13.9","Cell RNA - U-2 OS [nTPM]":"17.2","Cell RNA - U-2197 [nTPM]":"12.0","Cell RNA - U-251 MG [nTPM]":"12.2","Cell RNA - U-266\/70 [nTPM]":"13.7","Cell RNA - U-266\/84 [nTPM]":"19.8","Cell RNA - U-698 [nTPM]":"12.8","Cell RNA - U-87 MG [nTPM]":"17.7","Cell RNA - U-937 [nTPM]":"19.8","Cell RNA - WM-115 [nTPM]":"17.7","Blood RNA - basophil [nTPM]":"4.5","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"3.7","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"19.3","Brain RNA - basal ganglia [nTPM]":"18.8","Brain RNA - cerebellum [nTPM]":"21.3","Brain RNA - cerebral cortex [nTPM]":"28.6","Brain RNA - hippocampal formation [nTPM]":"19.4","Brain RNA - hypothalamus [nTPM]":"18.3","Brain RNA - medulla oblongata [nTPM]":"19.7","Brain RNA - midbrain [nTPM]":"18.6","Brain RNA - pons [nTPM]":"20.3","Brain RNA - spinal cord [nTPM]":"16.9","Brain RNA - thalamus [nTPM]":"18.7","Brain RNA - white matter [nTPM]":"20.0","Single Cell Type RNA - Adipocytes [nTPM]":"53.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.4","Single Cell Type RNA - Astrocytes [nTPM]":"39.2","Single Cell Type RNA - B-cells [nTPM]":"45.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.9","Single Cell Type RNA - Bipolar cells [nTPM]":"57.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"45.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"41.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"95.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.9","Single Cell Type RNA - dendritic cells [nTPM]":"47.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"40.0","Single Cell Type RNA - Early spermatids [nTPM]":"66.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"41.7","Single Cell Type RNA - Endothelial cells [nTPM]":"49.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.2","Single Cell Type RNA - Erythroid cells [nTPM]":"27.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"58.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.8","Single Cell Type RNA - Fibroblasts [nTPM]":"35.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"67.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"54.1","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"95.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"51.0","Single Cell Type RNA - Hepatocytes [nTPM]":"38.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.2","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.8","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"34.8","Single Cell Type RNA - Langerhans cells [nTPM]":"21.8","Single Cell Type RNA - Late spermatids [nTPM]":"22.1","Single Cell Type RNA - Leydig cells [nTPM]":"42.9","Single Cell Type RNA - Macrophages [nTPM]":"35.2","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"42.6","Single Cell Type RNA - Muller glia cells [nTPM]":"30.5","Single Cell Type RNA - NK-cells [nTPM]":"51.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"87.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.5","Single Cell Type RNA - Paneth cells [nTPM]":"39.5","Single Cell Type RNA - Peritubular cells [nTPM]":"33.4","Single Cell Type RNA - Plasma cells [nTPM]":"43.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"68.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.2","Single Cell Type RNA - Spermatocytes [nTPM]":"57.5","Single Cell Type RNA - Spermatogonia [nTPM]":"36.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.9","Single Cell Type RNA - T-cells [nTPM]":"45.5","Single Cell Type RNA - Theca cells [nTPM]":"68.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.0","Single Cell Type RNA - Urothelial cells [nTPM]":"28.7"},{"Gene":"SPNS2","Gene synonym":["SLC62A2"],"Ensembl":"ENSG00000183018","Gene description":"Sphingolipid transporter 2","Uniprot":["Q8IVW8"],"Chromosome":"17","Position":"4498881-4539035","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"51.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"32.7","Endothelial cells":"34.5","Microglial cells":"37.5","Oligodendrocytes":"97.8","Urothelial cells":"39.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"31.0","RPTEC TERT1":"161.7","SK-BR-3":"76.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068717"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA068717":"AB_2686021"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.3","Tissue RNA - adrenal gland [nTPM]":"2.6","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"14.0","Tissue RNA - bone marrow [nTPM]":"7.9","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"13.1","Tissue RNA - cerebral cortex [nTPM]":"18.2","Tissue RNA - cervix [nTPM]":"14.6","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"12.2","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"51.0","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"12.1","Tissue RNA - heart muscle [nTPM]":"10.7","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"12.1","Tissue RNA - kidney [nTPM]":"28.6","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"28.3","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"26.4","Tissue RNA - midbrain [nTPM]":"16.2","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"28.9","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"16.5","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"24.8","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"13.9","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"21.0","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"15.5","Tissue RNA - thymus [nTPM]":"1.7","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"6.6","Tissue RNA - vagina [nTPM]":"22.6","Tissue RNA - white matter [nTPM]":"25.1","Cell RNA - A-431 [nTPM]":"9.7","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"31.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"8.1","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"11.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"3.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"4.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"3.8","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"17.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"17.6","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"161.7","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"76.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"2.7","Cell RNA - THP-1 [nTPM]":"7.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"8.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"14.0","Brain RNA - cerebellum [nTPM]":"13.1","Brain RNA - cerebral cortex [nTPM]":"18.2","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"12.1","Brain RNA - medulla oblongata [nTPM]":"26.4","Brain RNA - midbrain [nTPM]":"16.2","Brain RNA - pons [nTPM]":"28.9","Brain RNA - spinal cord [nTPM]":"13.9","Brain RNA - thalamus [nTPM]":"15.5","Brain RNA - white matter [nTPM]":"25.1","Single Cell Type RNA - Adipocytes [nTPM]":"32.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"16.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"34.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"6.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"37.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"97.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"39.8"},{"Gene":"SPR","Gene synonym":["SDR38C1"],"Ensembl":"ENSG00000116096","Gene description":"Sepiapterin reductase","Uniprot":["P35270"],"Chromosome":"2","Position":"72887382-72892158","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"85.3","Exocrine glandular cells":"81.1","Proximal tubular cells":"91.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"classical monocyte":"8.3","intermediate monocyte":"2.4","myeloid DC":"8.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"8.9","monocytes":"8.3"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039505"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039505":"AB_10795466"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.9","Tissue RNA - adrenal gland [nTPM]":"50.8","Tissue RNA - amygdala [nTPM]":"26.0","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"27.2","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"20.0","Tissue RNA - cerebellum [nTPM]":"27.2","Tissue RNA - cerebral cortex [nTPM]":"61.4","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"39.6","Tissue RNA - colon [nTPM]":"36.4","Tissue RNA - duodenum [nTPM]":"23.4","Tissue RNA - endometrium 1 [nTPM]":"13.4","Tissue RNA - epididymis [nTPM]":"36.9","Tissue RNA - esophagus [nTPM]":"19.7","Tissue RNA - fallopian tube [nTPM]":"26.3","Tissue RNA - gallbladder [nTPM]":"11.9","Tissue RNA - heart muscle [nTPM]":"44.4","Tissue RNA - hippocampal formation [nTPM]":"26.8","Tissue RNA - hypothalamus [nTPM]":"30.0","Tissue RNA - kidney [nTPM]":"44.2","Tissue RNA - liver [nTPM]":"99.8","Tissue RNA - lung [nTPM]":"15.9","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"27.9","Tissue RNA - midbrain [nTPM]":"31.5","Tissue RNA - ovary [nTPM]":"12.2","Tissue RNA - pancreas [nTPM]":"63.5","Tissue RNA - parathyroid gland [nTPM]":"38.4","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"6.8","Tissue RNA - pons [nTPM]":"29.8","Tissue RNA - prostate [nTPM]":"26.2","Tissue RNA - rectum [nTPM]":"32.5","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"31.2","Tissue RNA - seminal vesicle [nTPM]":"16.7","Tissue RNA - skeletal muscle [nTPM]":"43.9","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"22.0","Tissue RNA - smooth muscle [nTPM]":"11.5","Tissue RNA - spinal cord [nTPM]":"27.9","Tissue RNA - spleen [nTPM]":"9.6","Tissue RNA - stomach 1 [nTPM]":"42.1","Tissue RNA - testis [nTPM]":"7.3","Tissue RNA - thalamus [nTPM]":"28.5","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"20.5","Tissue RNA - tongue [nTPM]":"25.4","Tissue RNA - tonsil [nTPM]":"5.1","Tissue RNA - urinary bladder [nTPM]":"25.2","Tissue RNA - vagina [nTPM]":"13.7","Tissue RNA - white matter [nTPM]":"28.0","Cell RNA - A-431 [nTPM]":"47.5","Cell RNA - A549 [nTPM]":"130.9","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"20.0","Cell RNA - ASC diff [nTPM]":"51.2","Cell RNA - ASC TERT1 [nTPM]":"18.5","Cell RNA - BEWO [nTPM]":"31.8","Cell RNA - BJ [nTPM]":"21.4","Cell RNA - BJ hTERT+ [nTPM]":"31.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.0","Cell RNA - CACO-2 [nTPM]":"84.0","Cell RNA - CAPAN-2 [nTPM]":"48.0","Cell RNA - Daudi [nTPM]":"34.5","Cell RNA - EFO-21 [nTPM]":"25.4","Cell RNA - fHDF\/TERT166 [nTPM]":"26.1","Cell RNA - GAMG [nTPM]":"80.6","Cell RNA - HaCaT [nTPM]":"43.9","Cell RNA - HAP1 [nTPM]":"58.1","Cell RNA - HBEC3-KT [nTPM]":"35.1","Cell RNA - HBF TERT88 [nTPM]":"13.3","Cell RNA - HDLM-2 [nTPM]":"10.0","Cell RNA - HEK 293 [nTPM]":"43.7","Cell RNA - HEL [nTPM]":"51.7","Cell RNA - HeLa [nTPM]":"30.8","Cell RNA - Hep G2 [nTPM]":"87.4","Cell RNA - HHSteC [nTPM]":"19.1","Cell RNA - HL-60 [nTPM]":"8.2","Cell RNA - HMC-1 [nTPM]":"13.6","Cell RNA - HSkMC [nTPM]":"16.7","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.6","Cell RNA - hTERT-HME1 [nTPM]":"19.7","Cell RNA - hTERT-RPE1 [nTPM]":"32.7","Cell RNA - HUVEC TERT2 [nTPM]":"42.6","Cell RNA - JURKAT [nTPM]":"25.4","Cell RNA - K-562 [nTPM]":"54.0","Cell RNA - Karpas-707 [nTPM]":"6.8","Cell RNA - LHCN-M2 [nTPM]":"21.4","Cell RNA - MCF7 [nTPM]":"100.5","Cell RNA - MOLT-4 [nTPM]":"3.3","Cell RNA - NB-4 [nTPM]":"31.1","Cell RNA - NTERA-2 [nTPM]":"10.9","Cell RNA - OE19 [nTPM]":"139.9","Cell RNA - PC-3 [nTPM]":"118.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"82.8","Cell RNA - RPMI-8226 [nTPM]":"20.3","Cell RNA - RPTEC TERT1 [nTPM]":"85.8","Cell RNA - RT4 [nTPM]":"73.4","Cell RNA - SCLC-21H [nTPM]":"8.0","Cell RNA - SH-SY5Y [nTPM]":"14.6","Cell RNA - SiHa [nTPM]":"39.6","Cell RNA - SK-BR-3 [nTPM]":"89.7","Cell RNA - SK-MEL-30 [nTPM]":"31.0","Cell RNA - SuSa [nTPM]":"16.9","Cell RNA - T-47d [nTPM]":"40.4","Cell RNA - THP-1 [nTPM]":"9.9","Cell RNA - TIME [nTPM]":"52.8","Cell RNA - U-138 MG [nTPM]":"17.4","Cell RNA - U-2 OS [nTPM]":"42.2","Cell RNA - U-2197 [nTPM]":"30.5","Cell RNA - U-251 MG [nTPM]":"38.7","Cell RNA - U-266\/70 [nTPM]":"7.2","Cell RNA - U-266\/84 [nTPM]":"16.9","Cell RNA - U-698 [nTPM]":"2.3","Cell RNA - U-87 MG [nTPM]":"25.0","Cell RNA - U-937 [nTPM]":"17.6","Cell RNA - WM-115 [nTPM]":"31.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"8.3","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"8.9","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.4","Brain RNA - amygdala [nTPM]":"26.0","Brain RNA - basal ganglia [nTPM]":"27.2","Brain RNA - cerebellum [nTPM]":"27.2","Brain RNA - cerebral cortex [nTPM]":"61.4","Brain RNA - hippocampal formation [nTPM]":"26.8","Brain RNA - hypothalamus [nTPM]":"30.0","Brain RNA - medulla oblongata [nTPM]":"27.9","Brain RNA - midbrain [nTPM]":"31.5","Brain RNA - pons [nTPM]":"29.8","Brain RNA - spinal cord [nTPM]":"27.9","Brain RNA - thalamus [nTPM]":"28.5","Brain RNA - white matter [nTPM]":"28.0","Single Cell Type RNA - Adipocytes [nTPM]":"13.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"85.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"56.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.2","Single Cell Type RNA - Endothelial cells [nTPM]":"16.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"6.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"81.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.6","Single Cell Type RNA - Fibroblasts [nTPM]":"13.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.7","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"62.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"9.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"20.8","Single Cell Type RNA - Muller glia cells [nTPM]":"13.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"43.3","Single Cell Type RNA - Paneth cells [nTPM]":"50.4","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"71.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"91.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"10.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"8.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"57.8","Single Cell Type RNA - Urothelial cells [nTPM]":"15.6"},{"Gene":"SPTAN1","Gene synonym":[],"Ensembl":"ENSG00000197694","Gene description":"Spectrin alpha, non-erythrocytic 1","Uniprot":["Q13813"],"Chromosome":"9","Position":"128552558-128633662","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin capping","Actin-binding","Calmodulin-binding"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"296.6","Cone photoreceptor cells":"310.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004581","HPA007927"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Vesicles","Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB004581":"AB_671135","HPA007927":"AB_1857435"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.84e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Tissue RNA - adipose tissue [nTPM]":"48.8","Tissue RNA - adrenal gland [nTPM]":"31.4","Tissue RNA - amygdala [nTPM]":"81.7","Tissue RNA - appendix [nTPM]":"38.6","Tissue RNA - basal ganglia [nTPM]":"85.0","Tissue RNA - bone marrow [nTPM]":"28.1","Tissue RNA - breast [nTPM]":"36.6","Tissue RNA - cerebellum [nTPM]":"54.4","Tissue RNA - cerebral cortex [nTPM]":"99.7","Tissue RNA - cervix [nTPM]":"39.4","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"47.3","Tissue RNA - duodenum [nTPM]":"24.7","Tissue RNA - endometrium 1 [nTPM]":"57.1","Tissue RNA - epididymis [nTPM]":"32.9","Tissue RNA - esophagus [nTPM]":"36.8","Tissue RNA - fallopian tube [nTPM]":"54.0","Tissue RNA - gallbladder [nTPM]":"32.5","Tissue RNA - heart muscle [nTPM]":"65.7","Tissue RNA - hippocampal formation [nTPM]":"90.9","Tissue RNA - hypothalamus [nTPM]":"43.5","Tissue RNA - kidney [nTPM]":"34.6","Tissue RNA - liver [nTPM]":"22.8","Tissue RNA - lung [nTPM]":"55.1","Tissue RNA - lymph node [nTPM]":"38.5","Tissue RNA - medulla oblongata [nTPM]":"142.7","Tissue RNA - midbrain [nTPM]":"49.6","Tissue RNA - ovary [nTPM]":"51.6","Tissue RNA - pancreas [nTPM]":"24.0","Tissue RNA - parathyroid gland [nTPM]":"47.1","Tissue RNA - pituitary gland [nTPM]":"32.5","Tissue RNA - placenta [nTPM]":"57.1","Tissue RNA - pons [nTPM]":"155.0","Tissue RNA - prostate [nTPM]":"32.7","Tissue RNA - rectum [nTPM]":"36.3","Tissue RNA - retina [nTPM]":"103.1","Tissue RNA - salivary gland [nTPM]":"31.9","Tissue RNA - seminal vesicle [nTPM]":"46.5","Tissue RNA - skeletal muscle [nTPM]":"23.9","Tissue RNA - skin 1 [nTPM]":"69.4","Tissue RNA - small intestine [nTPM]":"34.9","Tissue RNA - smooth muscle [nTPM]":"58.8","Tissue RNA - spinal cord [nTPM]":"65.6","Tissue RNA - spleen [nTPM]":"44.3","Tissue RNA - stomach 1 [nTPM]":"31.1","Tissue RNA - testis [nTPM]":"44.9","Tissue RNA - thalamus [nTPM]":"61.5","Tissue RNA - thymus [nTPM]":"45.4","Tissue RNA - thyroid gland [nTPM]":"38.4","Tissue RNA - tongue [nTPM]":"22.3","Tissue RNA - tonsil [nTPM]":"38.0","Tissue RNA - urinary bladder [nTPM]":"40.0","Tissue RNA - vagina [nTPM]":"36.4","Tissue RNA - white matter [nTPM]":"55.3","Cell RNA - A-431 [nTPM]":"108.1","Cell RNA - A549 [nTPM]":"116.9","Cell RNA - AF22 [nTPM]":"75.2","Cell RNA - AN3-CA [nTPM]":"83.4","Cell RNA - ASC diff [nTPM]":"107.6","Cell RNA - ASC TERT1 [nTPM]":"121.0","Cell RNA - BEWO [nTPM]":"61.5","Cell RNA - BJ [nTPM]":"90.2","Cell RNA - BJ hTERT+ [nTPM]":"75.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"99.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"74.1","Cell RNA - CACO-2 [nTPM]":"167.3","Cell RNA - CAPAN-2 [nTPM]":"74.6","Cell RNA - Daudi [nTPM]":"94.3","Cell RNA - EFO-21 [nTPM]":"78.3","Cell RNA - fHDF\/TERT166 [nTPM]":"137.0","Cell RNA - GAMG [nTPM]":"69.8","Cell RNA - HaCaT [nTPM]":"193.3","Cell RNA - HAP1 [nTPM]":"80.7","Cell RNA - HBEC3-KT [nTPM]":"90.4","Cell RNA - HBF TERT88 [nTPM]":"61.1","Cell RNA - HDLM-2 [nTPM]":"53.2","Cell RNA - HEK 293 [nTPM]":"47.9","Cell RNA - HEL [nTPM]":"15.9","Cell RNA - HeLa [nTPM]":"324.4","Cell RNA - Hep G2 [nTPM]":"94.4","Cell RNA - HHSteC [nTPM]":"61.3","Cell RNA - HL-60 [nTPM]":"70.9","Cell RNA - HMC-1 [nTPM]":"51.0","Cell RNA - HSkMC [nTPM]":"58.3","Cell RNA - hTCEpi [nTPM]":"71.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"166.3","Cell RNA - hTERT-HME1 [nTPM]":"55.8","Cell RNA - hTERT-RPE1 [nTPM]":"83.9","Cell RNA - HUVEC TERT2 [nTPM]":"134.4","Cell RNA - JURKAT [nTPM]":"87.2","Cell RNA - K-562 [nTPM]":"9.1","Cell RNA - Karpas-707 [nTPM]":"107.6","Cell RNA - LHCN-M2 [nTPM]":"98.6","Cell RNA - MCF7 [nTPM]":"74.6","Cell RNA - MOLT-4 [nTPM]":"136.3","Cell RNA - NB-4 [nTPM]":"29.5","Cell RNA - NTERA-2 [nTPM]":"96.1","Cell RNA - OE19 [nTPM]":"125.9","Cell RNA - PC-3 [nTPM]":"72.1","Cell RNA - REH [nTPM]":"91.0","Cell RNA - RH-30 [nTPM]":"90.2","Cell RNA - RPMI-8226 [nTPM]":"59.7","Cell RNA - RPTEC TERT1 [nTPM]":"80.2","Cell RNA - RT4 [nTPM]":"91.1","Cell RNA - SCLC-21H [nTPM]":"58.1","Cell RNA - SH-SY5Y [nTPM]":"91.1","Cell RNA - SiHa [nTPM]":"296.1","Cell RNA - SK-BR-3 [nTPM]":"40.3","Cell RNA - SK-MEL-30 [nTPM]":"42.9","Cell RNA - SuSa [nTPM]":"91.8","Cell RNA - T-47d [nTPM]":"70.0","Cell RNA - THP-1 [nTPM]":"19.8","Cell RNA - TIME [nTPM]":"232.5","Cell RNA - U-138 MG [nTPM]":"68.5","Cell RNA - U-2 OS [nTPM]":"102.2","Cell RNA - U-2197 [nTPM]":"100.0","Cell RNA - U-251 MG [nTPM]":"71.2","Cell RNA - U-266\/70 [nTPM]":"65.3","Cell RNA - U-266\/84 [nTPM]":"82.6","Cell RNA - U-698 [nTPM]":"51.8","Cell RNA - U-87 MG [nTPM]":"83.5","Cell RNA - U-937 [nTPM]":"31.5","Cell RNA - WM-115 [nTPM]":"65.9","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"9.7","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"13.5","Blood RNA - memory B-cell [nTPM]":"6.3","Blood RNA - memory CD4 T-cell [nTPM]":"12.4","Blood RNA - memory CD8 T-cell [nTPM]":"9.2","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"5.8","Blood RNA - naive CD4 T-cell [nTPM]":"7.6","Blood RNA - naive CD8 T-cell [nTPM]":"7.9","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"7.1","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"15.3","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"81.7","Brain RNA - basal ganglia [nTPM]":"85.0","Brain RNA - cerebellum [nTPM]":"54.4","Brain RNA - cerebral cortex [nTPM]":"99.7","Brain RNA - hippocampal formation [nTPM]":"90.9","Brain RNA - hypothalamus [nTPM]":"43.5","Brain RNA - medulla oblongata [nTPM]":"142.7","Brain RNA - midbrain [nTPM]":"49.6","Brain RNA - pons [nTPM]":"155.0","Brain RNA - spinal cord [nTPM]":"65.6","Brain RNA - thalamus [nTPM]":"61.5","Brain RNA - white matter [nTPM]":"55.3","Single Cell Type RNA - Adipocytes [nTPM]":"144.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.5","Single Cell Type RNA - Astrocytes [nTPM]":"123.7","Single Cell Type RNA - B-cells [nTPM]":"56.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"296.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"69.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"83.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"68.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"68.6","Single Cell Type RNA - Club cells [nTPM]":"33.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"101.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"310.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.5","Single Cell Type RNA - dendritic cells [nTPM]":"112.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"145.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"67.6","Single Cell Type RNA - Early spermatids [nTPM]":"18.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"108.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"71.4","Single Cell Type RNA - Endothelial cells [nTPM]":"103.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"56.9","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"159.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.0","Single Cell Type RNA - Fibroblasts [nTPM]":"77.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"76.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"87.5","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"47.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"96.8","Single Cell Type RNA - Hepatocytes [nTPM]":"36.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.2","Single Cell Type RNA - Horizontal cells [nTPM]":"124.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"183.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.1","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"22.2","Single Cell Type RNA - Langerhans cells [nTPM]":"29.4","Single Cell Type RNA - Late spermatids [nTPM]":"40.5","Single Cell Type RNA - Leydig cells [nTPM]":"85.1","Single Cell Type RNA - Macrophages [nTPM]":"32.8","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"74.9","Single Cell Type RNA - monocytes [nTPM]":"24.4","Single Cell Type RNA - Muller glia cells [nTPM]":"97.7","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"87.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"102.2","Single Cell Type RNA - Paneth cells [nTPM]":"93.0","Single Cell Type RNA - Peritubular cells [nTPM]":"94.8","Single Cell Type RNA - Plasma cells [nTPM]":"70.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"62.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"71.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"156.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"53.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"60.0","Single Cell Type RNA - Spermatocytes [nTPM]":"33.0","Single Cell Type RNA - Spermatogonia [nTPM]":"44.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.2","Single Cell Type RNA - T-cells [nTPM]":"95.4","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"73.6","Single Cell Type RNA - Urothelial cells [nTPM]":"65.7"},{"Gene":"SPTBN2","Gene synonym":["SCA5"],"Ensembl":"ENSG00000173898","Gene description":"Spectrin beta, non-erythrocytic 2","Uniprot":["O15020"],"Chromosome":"11","Position":"66682497-66729226","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin capping","Actin-binding"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"73.6","skin 1":"85.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"86.5","Cone photoreceptor cells":"104.3","Early spermatids":"30.9","Late spermatids":"77.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"45.6","NTERA-2":"49.1","SCLC-21H":"49.9","SK-BR-3":"52.3","T-47d":"67.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009844","HPA039293","HPA043529"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB009844":"AB_2194521","HPA039293":"AB_2676430","HPA043529":"AB_2678531"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.14e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"14.4","Tissue RNA - amygdala [nTPM]":"26.8","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"32.6","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"7.7","Tissue RNA - cerebellum [nTPM]":"29.7","Tissue RNA - cerebral cortex [nTPM]":"73.6","Tissue RNA - cervix [nTPM]":"14.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"39.8","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"1.4","Tissue RNA - hippocampal formation [nTPM]":"38.8","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"37.5","Tissue RNA - liver [nTPM]":"23.3","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"4.8","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"16.7","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"16.4","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"12.4","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"14.7","Tissue RNA - salivary gland [nTPM]":"29.6","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"85.5","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"52.8","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"16.5","Tissue RNA - white matter [nTPM]":"24.2","Cell RNA - A-431 [nTPM]":"20.5","Cell RNA - A549 [nTPM]":"7.4","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"4.8","Cell RNA - CAPAN-2 [nTPM]":"28.2","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"16.9","Cell RNA - HAP1 [nTPM]":"25.2","Cell RNA - HBEC3-KT [nTPM]":"2.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"45.6","Cell RNA - Hep G2 [nTPM]":"3.0","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"7.3","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"11.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"7.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.3","Cell RNA - JURKAT [nTPM]":"5.2","Cell RNA - K-562 [nTPM]":"7.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"35.2","Cell RNA - MOLT-4 [nTPM]":"6.3","Cell RNA - NB-4 [nTPM]":"3.5","Cell RNA - NTERA-2 [nTPM]":"49.1","Cell RNA - OE19 [nTPM]":"28.7","Cell RNA - PC-3 [nTPM]":"21.1","Cell RNA - REH [nTPM]":"23.8","Cell RNA - RH-30 [nTPM]":"2.8","Cell RNA - RPMI-8226 [nTPM]":"14.7","Cell RNA - RPTEC TERT1 [nTPM]":"9.6","Cell RNA - RT4 [nTPM]":"4.8","Cell RNA - SCLC-21H [nTPM]":"49.9","Cell RNA - SH-SY5Y [nTPM]":"29.4","Cell RNA - SiHa [nTPM]":"14.0","Cell RNA - SK-BR-3 [nTPM]":"52.3","Cell RNA - SK-MEL-30 [nTPM]":"3.2","Cell RNA - SuSa [nTPM]":"2.7","Cell RNA - T-47d [nTPM]":"67.2","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"1.4","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"8.6","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"11.5","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"14.7","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"26.8","Brain RNA - basal ganglia [nTPM]":"32.6","Brain RNA - cerebellum [nTPM]":"29.7","Brain RNA - cerebral cortex [nTPM]":"73.6","Brain RNA - hippocampal formation [nTPM]":"38.8","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"4.8","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"24.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"11.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"86.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"104.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.6","Single Cell Type RNA - Early spermatids [nTPM]":"30.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"24.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"77.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"8.5","Single Cell Type RNA - Spermatogonia [nTPM]":"9.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"SPTLC1","Gene synonym":["hLCB1","HSAN1","HSN1","LCB1","SPTI"],"Ensembl":"ENSG00000090054","Gene description":"Serine palmitoyltransferase long chain base subunit 1","Uniprot":["O15269"],"Chromosome":"9","Position":"92000087-92115413","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"94.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010860","CAB018747","HPA063907"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB018747":"AB_2195864","HPA010860":"AB_1080086","HPA063907":"AB_2685148"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Tissue RNA - adipose tissue [nTPM]":"35.6","Tissue RNA - adrenal gland [nTPM]":"32.6","Tissue RNA - amygdala [nTPM]":"24.0","Tissue RNA - appendix [nTPM]":"27.3","Tissue RNA - basal ganglia [nTPM]":"27.0","Tissue RNA - bone marrow [nTPM]":"23.3","Tissue RNA - breast [nTPM]":"44.1","Tissue RNA - cerebellum [nTPM]":"26.0","Tissue RNA - cerebral cortex [nTPM]":"34.2","Tissue RNA - cervix [nTPM]":"43.1","Tissue RNA - choroid plexus [nTPM]":"28.6","Tissue RNA - colon [nTPM]":"42.3","Tissue RNA - duodenum [nTPM]":"34.7","Tissue RNA - endometrium 1 [nTPM]":"40.4","Tissue RNA - epididymis [nTPM]":"41.3","Tissue RNA - esophagus [nTPM]":"54.3","Tissue RNA - fallopian tube [nTPM]":"36.7","Tissue RNA - gallbladder [nTPM]":"34.1","Tissue RNA - heart muscle [nTPM]":"21.5","Tissue RNA - hippocampal formation [nTPM]":"24.3","Tissue RNA - hypothalamus [nTPM]":"26.6","Tissue RNA - kidney [nTPM]":"42.8","Tissue RNA - liver [nTPM]":"23.4","Tissue RNA - lung [nTPM]":"33.6","Tissue RNA - lymph node [nTPM]":"25.7","Tissue RNA - medulla oblongata [nTPM]":"27.8","Tissue RNA - midbrain [nTPM]":"27.5","Tissue RNA - ovary [nTPM]":"43.8","Tissue RNA - pancreas [nTPM]":"26.5","Tissue RNA - parathyroid gland [nTPM]":"48.0","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"42.4","Tissue RNA - pons [nTPM]":"28.0","Tissue RNA - prostate [nTPM]":"32.9","Tissue RNA - rectum [nTPM]":"44.1","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"31.3","Tissue RNA - seminal vesicle [nTPM]":"28.1","Tissue RNA - skeletal muscle [nTPM]":"14.2","Tissue RNA - skin 1 [nTPM]":"41.3","Tissue RNA - small intestine [nTPM]":"37.9","Tissue RNA - smooth muscle [nTPM]":"31.4","Tissue RNA - spinal cord [nTPM]":"27.9","Tissue RNA - spleen [nTPM]":"26.3","Tissue RNA - stomach 1 [nTPM]":"37.1","Tissue RNA - testis [nTPM]":"26.5","Tissue RNA - thalamus [nTPM]":"25.6","Tissue RNA - thymus [nTPM]":"25.9","Tissue RNA - thyroid gland [nTPM]":"53.0","Tissue RNA - tongue [nTPM]":"18.6","Tissue RNA - tonsil [nTPM]":"34.4","Tissue RNA - urinary bladder [nTPM]":"37.2","Tissue RNA - vagina [nTPM]":"34.7","Tissue RNA - white matter [nTPM]":"31.6","Cell RNA - A-431 [nTPM]":"73.0","Cell RNA - A549 [nTPM]":"48.8","Cell RNA - AF22 [nTPM]":"46.8","Cell RNA - AN3-CA [nTPM]":"41.6","Cell RNA - ASC diff [nTPM]":"120.0","Cell RNA - ASC TERT1 [nTPM]":"92.0","Cell RNA - BEWO [nTPM]":"78.4","Cell RNA - BJ [nTPM]":"74.7","Cell RNA - BJ hTERT+ [nTPM]":"94.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"66.3","Cell RNA - CACO-2 [nTPM]":"31.5","Cell RNA - CAPAN-2 [nTPM]":"150.7","Cell RNA - Daudi [nTPM]":"38.6","Cell RNA - EFO-21 [nTPM]":"45.1","Cell RNA - fHDF\/TERT166 [nTPM]":"93.9","Cell RNA - GAMG [nTPM]":"78.3","Cell RNA - HaCaT [nTPM]":"198.4","Cell RNA - HAP1 [nTPM]":"49.7","Cell RNA - HBEC3-KT [nTPM]":"68.1","Cell RNA - HBF TERT88 [nTPM]":"73.0","Cell RNA - HDLM-2 [nTPM]":"39.8","Cell RNA - HEK 293 [nTPM]":"36.1","Cell RNA - HEL [nTPM]":"36.7","Cell RNA - HeLa [nTPM]":"32.7","Cell RNA - Hep G2 [nTPM]":"51.7","Cell RNA - HHSteC [nTPM]":"80.5","Cell RNA - HL-60 [nTPM]":"65.5","Cell RNA - HMC-1 [nTPM]":"49.9","Cell RNA - HSkMC [nTPM]":"82.6","Cell RNA - hTCEpi [nTPM]":"92.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.0","Cell RNA - hTERT-HME1 [nTPM]":"74.8","Cell RNA - hTERT-RPE1 [nTPM]":"72.3","Cell RNA - HUVEC TERT2 [nTPM]":"62.5","Cell RNA - JURKAT [nTPM]":"43.5","Cell RNA - K-562 [nTPM]":"83.8","Cell RNA - Karpas-707 [nTPM]":"46.6","Cell RNA - LHCN-M2 [nTPM]":"91.1","Cell RNA - MCF7 [nTPM]":"69.6","Cell RNA - MOLT-4 [nTPM]":"34.7","Cell RNA - NB-4 [nTPM]":"47.6","Cell RNA - NTERA-2 [nTPM]":"67.5","Cell RNA - OE19 [nTPM]":"97.4","Cell RNA - PC-3 [nTPM]":"57.9","Cell RNA - REH [nTPM]":"39.4","Cell RNA - RH-30 [nTPM]":"58.7","Cell RNA - RPMI-8226 [nTPM]":"33.3","Cell RNA - RPTEC TERT1 [nTPM]":"84.1","Cell RNA - RT4 [nTPM]":"37.9","Cell RNA - SCLC-21H [nTPM]":"35.0","Cell RNA - SH-SY5Y [nTPM]":"37.2","Cell RNA - SiHa [nTPM]":"104.4","Cell RNA - SK-BR-3 [nTPM]":"81.1","Cell RNA - SK-MEL-30 [nTPM]":"61.3","Cell RNA - SuSa [nTPM]":"62.4","Cell RNA - T-47d [nTPM]":"39.2","Cell RNA - THP-1 [nTPM]":"54.2","Cell RNA - TIME [nTPM]":"72.3","Cell RNA - U-138 MG [nTPM]":"58.8","Cell RNA - U-2 OS [nTPM]":"48.0","Cell RNA - U-2197 [nTPM]":"73.9","Cell RNA - U-251 MG [nTPM]":"56.8","Cell RNA - U-266\/70 [nTPM]":"33.2","Cell RNA - U-266\/84 [nTPM]":"44.4","Cell RNA - U-698 [nTPM]":"23.9","Cell RNA - U-87 MG [nTPM]":"74.2","Cell RNA - U-937 [nTPM]":"39.3","Cell RNA - WM-115 [nTPM]":"79.4","Blood RNA - basophil [nTPM]":"32.4","Blood RNA - classical monocyte [nTPM]":"33.1","Blood RNA - eosinophil [nTPM]":"20.2","Blood RNA - gdT-cell [nTPM]":"16.7","Blood RNA - intermediate monocyte [nTPM]":"36.1","Blood RNA - MAIT T-cell [nTPM]":"17.0","Blood RNA - memory B-cell [nTPM]":"15.4","Blood RNA - memory CD4 T-cell [nTPM]":"18.0","Blood RNA - memory CD8 T-cell [nTPM]":"17.4","Blood RNA - myeloid DC [nTPM]":"30.6","Blood RNA - naive B-cell [nTPM]":"15.5","Blood RNA - naive CD4 T-cell [nTPM]":"21.4","Blood RNA - naive CD8 T-cell [nTPM]":"16.6","Blood RNA - neutrophil [nTPM]":"33.3","Blood RNA - NK-cell [nTPM]":"18.5","Blood RNA - non-classical monocyte [nTPM]":"34.2","Blood RNA - plasmacytoid DC [nTPM]":"18.4","Blood RNA - T-reg [nTPM]":"25.7","Blood RNA - total PBMC [nTPM]":"25.5","Brain RNA - amygdala [nTPM]":"24.0","Brain RNA - basal ganglia [nTPM]":"27.0","Brain RNA - cerebellum [nTPM]":"26.0","Brain RNA - cerebral cortex [nTPM]":"34.2","Brain RNA - hippocampal formation [nTPM]":"24.3","Brain RNA - hypothalamus [nTPM]":"26.6","Brain RNA - medulla oblongata [nTPM]":"27.8","Brain RNA - midbrain [nTPM]":"27.5","Brain RNA - pons [nTPM]":"28.0","Brain RNA - spinal cord [nTPM]":"27.9","Brain RNA - thalamus [nTPM]":"25.6","Brain RNA - white matter [nTPM]":"31.6","Single Cell Type RNA - Adipocytes [nTPM]":"40.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.3","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"22.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"25.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - dendritic cells [nTPM]":"24.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"53.4","Single Cell Type RNA - Early spermatids [nTPM]":"94.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.5","Single Cell Type RNA - Endothelial cells [nTPM]":"23.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"7.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"56.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.6","Single Cell Type RNA - Fibroblasts [nTPM]":"32.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.4","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"26.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"4.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"10.3","Single Cell Type RNA - Late spermatids [nTPM]":"26.1","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"24.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"22.0","Single Cell Type RNA - Muller glia cells [nTPM]":"13.7","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"52.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"60.8","Single Cell Type RNA - Paneth cells [nTPM]":"7.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"26.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.5","Single Cell Type RNA - Spermatocytes [nTPM]":"35.3","Single Cell Type RNA - Spermatogonia [nTPM]":"25.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - T-cells [nTPM]":"21.9","Single Cell Type RNA - Theca cells [nTPM]":"33.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.9","Single Cell Type RNA - Urothelial cells [nTPM]":"14.5"},{"Gene":"SPTLC2","Gene synonym":["hLCB2a","KIAA0526","LCB2","LCB2A"],"Ensembl":"ENSG00000100596","Gene description":"Serine palmitoyltransferase long chain base subunit 2","Uniprot":["O15270"],"Chromosome":"14","Position":"77505997-77616637","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"164.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.6","Tissue RNA - adrenal gland [nTPM]":"12.2","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"12.6","Tissue RNA - basal ganglia [nTPM]":"26.7","Tissue RNA - bone marrow [nTPM]":"33.7","Tissue RNA - breast [nTPM]":"18.3","Tissue RNA - cerebellum [nTPM]":"24.0","Tissue RNA - cerebral cortex [nTPM]":"19.4","Tissue RNA - cervix [nTPM]":"15.2","Tissue RNA - choroid plexus [nTPM]":"9.9","Tissue RNA - colon [nTPM]":"18.5","Tissue RNA - duodenum [nTPM]":"14.5","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"22.8","Tissue RNA - fallopian tube [nTPM]":"14.2","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"15.3","Tissue RNA - hypothalamus [nTPM]":"18.1","Tissue RNA - kidney [nTPM]":"17.6","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"13.1","Tissue RNA - lymph node [nTPM]":"12.0","Tissue RNA - medulla oblongata [nTPM]":"30.7","Tissue RNA - midbrain [nTPM]":"21.5","Tissue RNA - ovary [nTPM]":"10.4","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"10.7","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"20.4","Tissue RNA - pons [nTPM]":"31.5","Tissue RNA - prostate [nTPM]":"8.4","Tissue RNA - rectum [nTPM]":"19.8","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"12.2","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"11.6","Tissue RNA - spinal cord [nTPM]":"25.3","Tissue RNA - spleen [nTPM]":"19.6","Tissue RNA - stomach 1 [nTPM]":"20.4","Tissue RNA - testis [nTPM]":"5.0","Tissue RNA - thalamus [nTPM]":"21.7","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"10.9","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"15.0","Tissue RNA - vagina [nTPM]":"10.8","Tissue RNA - white matter [nTPM]":"52.7","Cell RNA - A-431 [nTPM]":"28.9","Cell RNA - A549 [nTPM]":"18.5","Cell RNA - AF22 [nTPM]":"14.1","Cell RNA - AN3-CA [nTPM]":"15.5","Cell RNA - ASC diff [nTPM]":"14.3","Cell RNA - ASC TERT1 [nTPM]":"17.8","Cell RNA - BEWO [nTPM]":"23.7","Cell RNA - BJ [nTPM]":"41.7","Cell RNA - BJ hTERT+ [nTPM]":"30.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.3","Cell RNA - CACO-2 [nTPM]":"23.7","Cell RNA - CAPAN-2 [nTPM]":"62.3","Cell RNA - Daudi [nTPM]":"28.8","Cell RNA - EFO-21 [nTPM]":"10.4","Cell RNA - fHDF\/TERT166 [nTPM]":"42.7","Cell RNA - GAMG [nTPM]":"14.5","Cell RNA - HaCaT [nTPM]":"34.7","Cell RNA - HAP1 [nTPM]":"38.1","Cell RNA - HBEC3-KT [nTPM]":"23.7","Cell RNA - HBF TERT88 [nTPM]":"42.5","Cell RNA - HDLM-2 [nTPM]":"12.6","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"82.5","Cell RNA - HeLa [nTPM]":"13.4","Cell RNA - Hep G2 [nTPM]":"14.3","Cell RNA - HHSteC [nTPM]":"12.1","Cell RNA - HL-60 [nTPM]":"8.4","Cell RNA - HMC-1 [nTPM]":"25.8","Cell RNA - HSkMC [nTPM]":"11.7","Cell RNA - hTCEpi [nTPM]":"11.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.4","Cell RNA - hTERT-HME1 [nTPM]":"20.4","Cell RNA - hTERT-RPE1 [nTPM]":"16.3","Cell RNA - HUVEC TERT2 [nTPM]":"40.6","Cell RNA - JURKAT [nTPM]":"19.4","Cell RNA - K-562 [nTPM]":"16.2","Cell RNA - Karpas-707 [nTPM]":"13.5","Cell RNA - LHCN-M2 [nTPM]":"16.2","Cell RNA - MCF7 [nTPM]":"24.9","Cell RNA - MOLT-4 [nTPM]":"22.2","Cell RNA - NB-4 [nTPM]":"28.7","Cell RNA - NTERA-2 [nTPM]":"9.2","Cell RNA - OE19 [nTPM]":"45.4","Cell RNA - PC-3 [nTPM]":"16.8","Cell RNA - REH [nTPM]":"23.5","Cell RNA - RH-30 [nTPM]":"14.3","Cell RNA - RPMI-8226 [nTPM]":"10.0","Cell RNA - RPTEC TERT1 [nTPM]":"32.9","Cell RNA - RT4 [nTPM]":"63.4","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"17.1","Cell RNA - SiHa [nTPM]":"15.0","Cell RNA - SK-BR-3 [nTPM]":"50.3","Cell RNA - SK-MEL-30 [nTPM]":"15.8","Cell RNA - SuSa [nTPM]":"24.7","Cell RNA - T-47d [nTPM]":"61.8","Cell RNA - THP-1 [nTPM]":"15.3","Cell RNA - TIME [nTPM]":"25.9","Cell RNA - U-138 MG [nTPM]":"25.7","Cell RNA - U-2 OS [nTPM]":"18.2","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"9.7","Cell RNA - U-266\/70 [nTPM]":"7.6","Cell RNA - U-266\/84 [nTPM]":"13.4","Cell RNA - U-698 [nTPM]":"19.1","Cell RNA - U-87 MG [nTPM]":"17.3","Cell RNA - U-937 [nTPM]":"29.4","Cell RNA - WM-115 [nTPM]":"14.8","Blood RNA - basophil [nTPM]":"18.3","Blood RNA - classical monocyte [nTPM]":"31.3","Blood RNA - eosinophil [nTPM]":"27.1","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"24.2","Blood RNA - MAIT T-cell [nTPM]":"5.7","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"5.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"31.2","Blood RNA - naive B-cell [nTPM]":"7.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.8","Blood RNA - neutrophil [nTPM]":"19.1","Blood RNA - NK-cell [nTPM]":"17.7","Blood RNA - non-classical monocyte [nTPM]":"31.8","Blood RNA - plasmacytoid DC [nTPM]":"11.1","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"13.4","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"26.7","Brain RNA - cerebellum [nTPM]":"24.0","Brain RNA - cerebral cortex [nTPM]":"19.4","Brain RNA - hippocampal formation [nTPM]":"15.3","Brain RNA - hypothalamus [nTPM]":"18.1","Brain RNA - medulla oblongata [nTPM]":"30.7","Brain RNA - midbrain [nTPM]":"21.5","Brain RNA - pons [nTPM]":"31.5","Brain RNA - spinal cord [nTPM]":"25.3","Brain RNA - thalamus [nTPM]":"21.7","Brain RNA - white matter [nTPM]":"52.7","Single Cell Type RNA - Adipocytes [nTPM]":"125.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.3","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"27.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"15.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"30.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - dendritic cells [nTPM]":"28.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"44.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.0","Single Cell Type RNA - Endothelial cells [nTPM]":"53.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"51.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.3","Single Cell Type RNA - Fibroblasts [nTPM]":"18.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.0","Single Cell Type RNA - granulocytes [nTPM]":"51.3","Single Cell Type RNA - Granulosa cells [nTPM]":"37.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"68.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"75.9","Single Cell Type RNA - Langerhans cells [nTPM]":"19.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"66.2","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"83.4","Single Cell Type RNA - monocytes [nTPM]":"51.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.8","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"59.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"164.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.0","Single Cell Type RNA - Paneth cells [nTPM]":"30.4","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"11.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.0","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.5","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"19.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"23.3","Single Cell Type RNA - Theca cells [nTPM]":"14.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.0","Single Cell Type RNA - Urothelial cells [nTPM]":"60.0"},{"Gene":"SQSTM1","Gene synonym":["A170","OSIL","p60","p62","p62B","PDB3"],"Ensembl":"ENSG00000161011","Gene description":"Sequestosome 1","Uniprot":["Q13501"],"Chromosome":"5","Position":"179806398-179838078","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Autophagy","Differentiation","Immunity"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"1183.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"2045.0","Urothelial cells":"2233.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"1923.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004587","HPA064165","HPA068843"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"81000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004587":"AB_628279","HPA064165":"AB_2685203","HPA068843":"AB_2732120"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.31e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"335.0","Tissue RNA - adrenal gland [nTPM]":"472.6","Tissue RNA - amygdala [nTPM]":"171.4","Tissue RNA - appendix [nTPM]":"86.0","Tissue RNA - basal ganglia [nTPM]":"208.8","Tissue RNA - bone marrow [nTPM]":"135.8","Tissue RNA - breast [nTPM]":"269.5","Tissue RNA - cerebellum [nTPM]":"199.6","Tissue RNA - cerebral cortex [nTPM]":"207.2","Tissue RNA - cervix [nTPM]":"242.8","Tissue RNA - choroid plexus [nTPM]":"218.9","Tissue RNA - colon [nTPM]":"262.0","Tissue RNA - duodenum [nTPM]":"112.1","Tissue RNA - endometrium 1 [nTPM]":"278.8","Tissue RNA - epididymis [nTPM]":"91.7","Tissue RNA - esophagus [nTPM]":"192.3","Tissue RNA - fallopian tube [nTPM]":"207.5","Tissue RNA - gallbladder [nTPM]":"188.2","Tissue RNA - heart muscle [nTPM]":"310.1","Tissue RNA - hippocampal formation [nTPM]":"163.8","Tissue RNA - hypothalamus [nTPM]":"200.6","Tissue RNA - kidney [nTPM]":"221.5","Tissue RNA - liver [nTPM]":"392.0","Tissue RNA - lung [nTPM]":"263.4","Tissue RNA - lymph node [nTPM]":"81.4","Tissue RNA - medulla oblongata [nTPM]":"203.9","Tissue RNA - midbrain [nTPM]":"183.3","Tissue RNA - ovary [nTPM]":"235.6","Tissue RNA - pancreas [nTPM]":"231.3","Tissue RNA - parathyroid gland [nTPM]":"121.4","Tissue RNA - pituitary gland [nTPM]":"181.5","Tissue RNA - placenta [nTPM]":"118.7","Tissue RNA - pons [nTPM]":"190.5","Tissue RNA - prostate [nTPM]":"206.2","Tissue RNA - rectum [nTPM]":"82.3","Tissue RNA - retina [nTPM]":"46.4","Tissue RNA - salivary gland [nTPM]":"289.7","Tissue RNA - seminal vesicle [nTPM]":"174.2","Tissue RNA - skeletal muscle [nTPM]":"1183.4","Tissue RNA - skin 1 [nTPM]":"194.7","Tissue RNA - small intestine [nTPM]":"187.4","Tissue RNA - smooth muscle [nTPM]":"132.7","Tissue RNA - spinal cord [nTPM]":"179.5","Tissue RNA - spleen [nTPM]":"179.0","Tissue RNA - stomach 1 [nTPM]":"263.6","Tissue RNA - testis [nTPM]":"65.7","Tissue RNA - thalamus [nTPM]":"205.7","Tissue RNA - thymus [nTPM]":"89.4","Tissue RNA - thyroid gland [nTPM]":"316.4","Tissue RNA - tongue [nTPM]":"287.2","Tissue RNA - tonsil [nTPM]":"96.4","Tissue RNA - urinary bladder [nTPM]":"347.3","Tissue RNA - vagina [nTPM]":"211.0","Tissue RNA - white matter [nTPM]":"236.5","Cell RNA - A-431 [nTPM]":"130.1","Cell RNA - A549 [nTPM]":"740.6","Cell RNA - AF22 [nTPM]":"36.9","Cell RNA - AN3-CA [nTPM]":"114.3","Cell RNA - ASC diff [nTPM]":"547.8","Cell RNA - ASC TERT1 [nTPM]":"384.8","Cell RNA - BEWO [nTPM]":"546.3","Cell RNA - BJ [nTPM]":"187.9","Cell RNA - BJ hTERT+ [nTPM]":"596.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"164.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"201.2","Cell RNA - CACO-2 [nTPM]":"154.6","Cell RNA - CAPAN-2 [nTPM]":"532.9","Cell RNA - Daudi [nTPM]":"16.0","Cell RNA - EFO-21 [nTPM]":"522.7","Cell RNA - fHDF\/TERT166 [nTPM]":"298.9","Cell RNA - GAMG [nTPM]":"898.3","Cell RNA - HaCaT [nTPM]":"170.8","Cell RNA - HAP1 [nTPM]":"79.9","Cell RNA - HBEC3-KT [nTPM]":"181.9","Cell RNA - HBF TERT88 [nTPM]":"76.9","Cell RNA - HDLM-2 [nTPM]":"1923.9","Cell RNA - HEK 293 [nTPM]":"97.6","Cell RNA - HEL [nTPM]":"58.5","Cell RNA - HeLa [nTPM]":"303.9","Cell RNA - Hep G2 [nTPM]":"223.4","Cell RNA - HHSteC [nTPM]":"1167.2","Cell RNA - HL-60 [nTPM]":"59.9","Cell RNA - HMC-1 [nTPM]":"365.0","Cell RNA - HSkMC [nTPM]":"337.1","Cell RNA - hTCEpi [nTPM]":"181.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"273.0","Cell RNA - hTERT-HME1 [nTPM]":"441.5","Cell RNA - hTERT-RPE1 [nTPM]":"390.8","Cell RNA - HUVEC TERT2 [nTPM]":"152.6","Cell RNA - JURKAT [nTPM]":"17.3","Cell RNA - K-562 [nTPM]":"68.0","Cell RNA - Karpas-707 [nTPM]":"472.1","Cell RNA - LHCN-M2 [nTPM]":"327.0","Cell RNA - MCF7 [nTPM]":"111.6","Cell RNA - MOLT-4 [nTPM]":"26.4","Cell RNA - NB-4 [nTPM]":"62.0","Cell RNA - NTERA-2 [nTPM]":"93.8","Cell RNA - OE19 [nTPM]":"410.0","Cell RNA - PC-3 [nTPM]":"195.1","Cell RNA - REH [nTPM]":"54.8","Cell RNA - RH-30 [nTPM]":"78.8","Cell RNA - RPMI-8226 [nTPM]":"213.7","Cell RNA - RPTEC TERT1 [nTPM]":"243.6","Cell RNA - RT4 [nTPM]":"609.6","Cell RNA - SCLC-21H [nTPM]":"79.0","Cell RNA - SH-SY5Y [nTPM]":"74.5","Cell RNA - SiHa [nTPM]":"253.2","Cell RNA - SK-BR-3 [nTPM]":"274.3","Cell RNA - SK-MEL-30 [nTPM]":"662.2","Cell RNA - SuSa [nTPM]":"62.3","Cell RNA - T-47d [nTPM]":"143.8","Cell RNA - THP-1 [nTPM]":"120.4","Cell RNA - TIME [nTPM]":"286.2","Cell RNA - U-138 MG [nTPM]":"243.1","Cell RNA - U-2 OS [nTPM]":"103.4","Cell RNA - U-2197 [nTPM]":"252.3","Cell RNA - U-251 MG [nTPM]":"271.6","Cell RNA - U-266\/70 [nTPM]":"723.7","Cell RNA - U-266\/84 [nTPM]":"819.3","Cell RNA - U-698 [nTPM]":"73.5","Cell RNA - U-87 MG [nTPM]":"521.1","Cell RNA - U-937 [nTPM]":"111.6","Cell RNA - WM-115 [nTPM]":"338.4","Blood RNA - basophil [nTPM]":"807.6","Blood RNA - classical monocyte [nTPM]":"412.3","Blood RNA - eosinophil [nTPM]":"422.2","Blood RNA - gdT-cell [nTPM]":"194.7","Blood RNA - intermediate monocyte [nTPM]":"268.3","Blood RNA - MAIT T-cell [nTPM]":"231.3","Blood RNA - memory B-cell [nTPM]":"156.5","Blood RNA - memory CD4 T-cell [nTPM]":"170.1","Blood RNA - memory CD8 T-cell [nTPM]":"174.6","Blood RNA - myeloid DC [nTPM]":"227.5","Blood RNA - naive B-cell [nTPM]":"168.2","Blood RNA - naive CD4 T-cell [nTPM]":"131.8","Blood RNA - naive CD8 T-cell [nTPM]":"139.1","Blood RNA - neutrophil [nTPM]":"672.6","Blood RNA - NK-cell [nTPM]":"196.3","Blood RNA - non-classical monocyte [nTPM]":"260.3","Blood RNA - plasmacytoid DC [nTPM]":"89.6","Blood RNA - T-reg [nTPM]":"262.1","Blood RNA - total PBMC [nTPM]":"439.8","Brain RNA - amygdala [nTPM]":"171.4","Brain RNA - basal ganglia [nTPM]":"208.8","Brain RNA - cerebellum [nTPM]":"199.6","Brain RNA - cerebral cortex [nTPM]":"207.2","Brain RNA - hippocampal formation [nTPM]":"163.8","Brain RNA - hypothalamus [nTPM]":"200.6","Brain RNA - medulla oblongata [nTPM]":"203.9","Brain RNA - midbrain [nTPM]":"183.3","Brain RNA - pons [nTPM]":"190.5","Brain RNA - spinal cord [nTPM]":"179.5","Brain RNA - thalamus [nTPM]":"205.7","Brain RNA - white matter [nTPM]":"236.5","Single Cell Type RNA - Adipocytes [nTPM]":"411.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"185.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"248.8","Single Cell Type RNA - Astrocytes [nTPM]":"36.9","Single Cell Type RNA - B-cells [nTPM]":"280.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"297.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1289.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"320.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"799.6","Single Cell Type RNA - Bipolar cells [nTPM]":"81.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"280.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"253.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"314.5","Single Cell Type RNA - Club cells [nTPM]":"247.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"121.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"266.8","Single Cell Type RNA - dendritic cells [nTPM]":"276.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"572.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"234.8","Single Cell Type RNA - Ductal cells [nTPM]":"906.0","Single Cell Type RNA - Early spermatids [nTPM]":"34.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"408.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"255.4","Single Cell Type RNA - Endothelial cells [nTPM]":"415.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"340.4","Single Cell Type RNA - Erythroid cells [nTPM]":"89.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"686.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"133.2","Single Cell Type RNA - Fibroblasts [nTPM]":"516.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1270.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"589.7","Single Cell Type RNA - granulocytes [nTPM]":"386.3","Single Cell Type RNA - Granulosa cells [nTPM]":"73.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"142.5","Single Cell Type RNA - Hepatocytes [nTPM]":"297.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"288.3","Single Cell Type RNA - Horizontal cells [nTPM]":"90.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"337.2","Single Cell Type RNA - Ionocytes [nTPM]":"236.0","Single Cell Type RNA - Kupffer cells [nTPM]":"149.8","Single Cell Type RNA - Langerhans cells [nTPM]":"556.3","Single Cell Type RNA - Late spermatids [nTPM]":"72.2","Single Cell Type RNA - Leydig cells [nTPM]":"325.3","Single Cell Type RNA - Macrophages [nTPM]":"388.3","Single Cell Type RNA - Melanocytes [nTPM]":"231.3","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"611.3","Single Cell Type RNA - Muller glia cells [nTPM]":"143.3","Single Cell Type RNA - NK-cells [nTPM]":"125.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"639.4","Single Cell Type RNA - Paneth cells [nTPM]":"618.9","Single Cell Type RNA - Peritubular cells [nTPM]":"259.2","Single Cell Type RNA - Plasma cells [nTPM]":"606.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1281.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"311.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"327.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"190.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.5","Single Cell Type RNA - Sertoli cells [nTPM]":"164.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"356.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"316.1","Single Cell Type RNA - Spermatocytes [nTPM]":"45.5","Single Cell Type RNA - Spermatogonia [nTPM]":"48.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"595.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"259.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2045.0","Single Cell Type RNA - T-cells [nTPM]":"259.9","Single Cell Type RNA - Theca cells [nTPM]":"133.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"242.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2233.9"},{"Gene":"SRPX2","Gene synonym":["SRPUL"],"Ensembl":"ENSG00000102359","Gene description":"Sushi repeat containing protein X-linked 2","Uniprot":["O60687"],"Chromosome":"X","Position":"100644195-100675788","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Angiogenesis","Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"31.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"20.9","Fibroblasts":"34.3","Granulosa cells":"21.6","Microglial cells":"37.5","Skeletal myocytes":"17.5","Urothelial cells":"49.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"282.3","ASC TERT1":"116.9","HSkMC":"103.3","HUVEC TERT2":"72.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"2.8"},"Antibody":["HPA038786"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038786":"AB_10672724"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"31.8","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"4.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"20.7","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"11.3","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"7.1","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"17.7","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"12.7","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"5.8","Tissue RNA - kidney [nTPM]":"13.9","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"13.8","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"3.4","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"12.9","Tissue RNA - stomach 1 [nTPM]":"4.5","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"7.4","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"4.3","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"16.8","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"2.5","Cell RNA - A-431 [nTPM]":"11.7","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"2.9","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"282.3","Cell RNA - ASC TERT1 [nTPM]":"116.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"26.3","Cell RNA - BJ hTERT+ [nTPM]":"19.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.1","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"17.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"15.9","Cell RNA - GAMG [nTPM]":"7.5","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"13.1","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"2.8","Cell RNA - HHSteC [nTPM]":"29.3","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"103.3","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.8","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"24.6","Cell RNA - HUVEC TERT2 [nTPM]":"72.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"27.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"11.4","Cell RNA - RT4 [nTPM]":"37.6","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"6.1","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"36.7","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"12.3","Cell RNA - U-2197 [nTPM]":"10.3","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"18.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"8.5","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"4.5","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"5.8","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"7.4","Brain RNA - white matter [nTPM]":"2.5","Single Cell Type RNA - Adipocytes [nTPM]":"20.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"13.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"34.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"21.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"15.8","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"37.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"2.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"49.1"},{"Gene":"SSBP1","Gene synonym":["mtSSB","SSBP"],"Ensembl":"ENSG00000106028","Gene description":"Single stranded DNA binding protein 1","Uniprot":["Q04837"],"Chromosome":"7","Position":"141738334-141787922","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA replication"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002866"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA002866":"AB_1080092"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.42e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.40e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Tissue RNA - adipose tissue [nTPM]":"86.1","Tissue RNA - adrenal gland [nTPM]":"105.0","Tissue RNA - amygdala [nTPM]":"70.5","Tissue RNA - appendix [nTPM]":"80.9","Tissue RNA - basal ganglia [nTPM]":"72.6","Tissue RNA - bone marrow [nTPM]":"89.9","Tissue RNA - breast [nTPM]":"97.0","Tissue RNA - cerebellum [nTPM]":"72.3","Tissue RNA - cerebral cortex [nTPM]":"101.1","Tissue RNA - cervix [nTPM]":"75.1","Tissue RNA - choroid plexus [nTPM]":"65.8","Tissue RNA - colon [nTPM]":"94.1","Tissue RNA - duodenum [nTPM]":"70.4","Tissue RNA - endometrium 1 [nTPM]":"83.6","Tissue RNA - epididymis [nTPM]":"107.7","Tissue RNA - esophagus [nTPM]":"125.9","Tissue RNA - fallopian tube [nTPM]":"74.0","Tissue RNA - gallbladder [nTPM]":"54.0","Tissue RNA - heart muscle [nTPM]":"135.0","Tissue RNA - hippocampal formation [nTPM]":"71.5","Tissue RNA - hypothalamus [nTPM]":"74.5","Tissue RNA - kidney [nTPM]":"105.4","Tissue RNA - liver [nTPM]":"120.4","Tissue RNA - lung [nTPM]":"62.9","Tissue RNA - lymph node [nTPM]":"97.0","Tissue RNA - medulla oblongata [nTPM]":"72.5","Tissue RNA - midbrain [nTPM]":"74.4","Tissue RNA - ovary [nTPM]":"85.3","Tissue RNA - pancreas [nTPM]":"87.8","Tissue RNA - parathyroid gland [nTPM]":"93.6","Tissue RNA - pituitary gland [nTPM]":"64.8","Tissue RNA - placenta [nTPM]":"78.4","Tissue RNA - pons [nTPM]":"72.8","Tissue RNA - prostate [nTPM]":"64.9","Tissue RNA - rectum [nTPM]":"85.3","Tissue RNA - retina [nTPM]":"58.2","Tissue RNA - salivary gland [nTPM]":"77.4","Tissue RNA - seminal vesicle [nTPM]":"70.4","Tissue RNA - skeletal muscle [nTPM]":"141.2","Tissue RNA - skin 1 [nTPM]":"88.4","Tissue RNA - small intestine [nTPM]":"77.5","Tissue RNA - smooth muscle [nTPM]":"76.1","Tissue RNA - spinal cord [nTPM]":"72.5","Tissue RNA - spleen [nTPM]":"80.8","Tissue RNA - stomach 1 [nTPM]":"93.1","Tissue RNA - testis [nTPM]":"80.8","Tissue RNA - thalamus [nTPM]":"70.8","Tissue RNA - thymus [nTPM]":"96.6","Tissue RNA - thyroid gland [nTPM]":"82.7","Tissue RNA - tongue [nTPM]":"94.1","Tissue RNA - tonsil [nTPM]":"112.8","Tissue RNA - urinary bladder [nTPM]":"91.8","Tissue RNA - vagina [nTPM]":"82.1","Tissue RNA - white matter [nTPM]":"74.4","Cell RNA - A-431 [nTPM]":"280.6","Cell RNA - A549 [nTPM]":"333.6","Cell RNA - AF22 [nTPM]":"281.6","Cell RNA - AN3-CA [nTPM]":"369.2","Cell RNA - ASC diff [nTPM]":"125.5","Cell RNA - ASC TERT1 [nTPM]":"193.2","Cell RNA - BEWO [nTPM]":"262.2","Cell RNA - BJ [nTPM]":"208.7","Cell RNA - BJ hTERT+ [nTPM]":"193.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"256.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"287.9","Cell RNA - CACO-2 [nTPM]":"353.7","Cell RNA - CAPAN-2 [nTPM]":"330.5","Cell RNA - Daudi [nTPM]":"414.0","Cell RNA - EFO-21 [nTPM]":"267.6","Cell RNA - fHDF\/TERT166 [nTPM]":"173.5","Cell RNA - GAMG [nTPM]":"421.8","Cell RNA - HaCaT [nTPM]":"210.2","Cell RNA - HAP1 [nTPM]":"349.5","Cell RNA - HBEC3-KT [nTPM]":"347.4","Cell RNA - HBF TERT88 [nTPM]":"369.6","Cell RNA - HDLM-2 [nTPM]":"220.8","Cell RNA - HEK 293 [nTPM]":"339.1","Cell RNA - HEL [nTPM]":"226.1","Cell RNA - HeLa [nTPM]":"253.6","Cell RNA - Hep G2 [nTPM]":"322.3","Cell RNA - HHSteC [nTPM]":"242.6","Cell RNA - HL-60 [nTPM]":"644.9","Cell RNA - HMC-1 [nTPM]":"166.8","Cell RNA - HSkMC [nTPM]":"179.9","Cell RNA - hTCEpi [nTPM]":"230.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"257.4","Cell RNA - hTERT-HME1 [nTPM]":"373.0","Cell RNA - hTERT-RPE1 [nTPM]":"177.7","Cell RNA - HUVEC TERT2 [nTPM]":"316.2","Cell RNA - JURKAT [nTPM]":"279.9","Cell RNA - K-562 [nTPM]":"552.8","Cell RNA - Karpas-707 [nTPM]":"184.0","Cell RNA - LHCN-M2 [nTPM]":"343.4","Cell RNA - MCF7 [nTPM]":"430.9","Cell RNA - MOLT-4 [nTPM]":"477.3","Cell RNA - NB-4 [nTPM]":"837.2","Cell RNA - NTERA-2 [nTPM]":"634.1","Cell RNA - OE19 [nTPM]":"476.8","Cell RNA - PC-3 [nTPM]":"403.0","Cell RNA - REH [nTPM]":"262.6","Cell RNA - RH-30 [nTPM]":"258.2","Cell RNA - RPMI-8226 [nTPM]":"578.5","Cell RNA - RPTEC TERT1 [nTPM]":"340.9","Cell RNA - RT4 [nTPM]":"286.7","Cell RNA - SCLC-21H [nTPM]":"256.4","Cell RNA - SH-SY5Y [nTPM]":"352.5","Cell RNA - SiHa [nTPM]":"236.8","Cell RNA - SK-BR-3 [nTPM]":"323.7","Cell RNA - SK-MEL-30 [nTPM]":"319.8","Cell RNA - SuSa [nTPM]":"213.7","Cell RNA - T-47d [nTPM]":"210.7","Cell RNA - THP-1 [nTPM]":"267.2","Cell RNA - TIME [nTPM]":"239.6","Cell RNA - U-138 MG [nTPM]":"183.0","Cell RNA - U-2 OS [nTPM]":"171.6","Cell RNA - U-2197 [nTPM]":"282.1","Cell RNA - U-251 MG [nTPM]":"533.8","Cell RNA - U-266\/70 [nTPM]":"328.6","Cell RNA - U-266\/84 [nTPM]":"465.9","Cell RNA - U-698 [nTPM]":"796.1","Cell RNA - U-87 MG [nTPM]":"369.9","Cell RNA - U-937 [nTPM]":"577.6","Cell RNA - WM-115 [nTPM]":"395.8","Blood RNA - basophil [nTPM]":"136.1","Blood RNA - classical monocyte [nTPM]":"69.9","Blood RNA - eosinophil [nTPM]":"76.8","Blood RNA - gdT-cell [nTPM]":"71.7","Blood RNA - intermediate monocyte [nTPM]":"96.1","Blood RNA - MAIT T-cell [nTPM]":"107.7","Blood RNA - memory B-cell [nTPM]":"106.3","Blood RNA - memory CD4 T-cell [nTPM]":"113.8","Blood RNA - memory CD8 T-cell [nTPM]":"98.9","Blood RNA - myeloid DC [nTPM]":"90.6","Blood RNA - naive B-cell [nTPM]":"92.0","Blood RNA - naive CD4 T-cell [nTPM]":"101.1","Blood RNA - naive CD8 T-cell [nTPM]":"113.7","Blood RNA - neutrophil [nTPM]":"20.6","Blood RNA - NK-cell [nTPM]":"98.8","Blood RNA - non-classical monocyte [nTPM]":"99.8","Blood RNA - plasmacytoid DC [nTPM]":"104.0","Blood RNA - T-reg [nTPM]":"123.8","Blood RNA - total PBMC [nTPM]":"116.3","Brain RNA - amygdala [nTPM]":"70.5","Brain RNA - basal ganglia [nTPM]":"72.6","Brain RNA - cerebellum [nTPM]":"72.3","Brain RNA - cerebral cortex [nTPM]":"101.1","Brain RNA - hippocampal formation [nTPM]":"71.5","Brain RNA - hypothalamus [nTPM]":"74.5","Brain RNA - medulla oblongata [nTPM]":"72.5","Brain RNA - midbrain [nTPM]":"74.4","Brain RNA - pons [nTPM]":"72.8","Brain RNA - spinal cord [nTPM]":"72.5","Brain RNA - thalamus [nTPM]":"70.8","Brain RNA - white matter [nTPM]":"74.4","Single Cell Type RNA - Adipocytes [nTPM]":"151.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"102.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"104.7","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"135.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"116.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"199.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"477.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"98.4","Single Cell Type RNA - Bipolar cells [nTPM]":"58.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"114.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"178.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"279.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"148.7","Single Cell Type RNA - Club cells [nTPM]":"242.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"150.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"311.0","Single Cell Type RNA - dendritic cells [nTPM]":"139.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"92.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"350.2","Single Cell Type RNA - Ductal cells [nTPM]":"310.3","Single Cell Type RNA - Early spermatids [nTPM]":"187.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"160.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"162.3","Single Cell Type RNA - Endothelial cells [nTPM]":"136.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"96.3","Single Cell Type RNA - Erythroid cells [nTPM]":"111.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"353.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"313.7","Single Cell Type RNA - Fibroblasts [nTPM]":"140.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"92.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"169.8","Single Cell Type RNA - granulocytes [nTPM]":"151.9","Single Cell Type RNA - Granulosa cells [nTPM]":"163.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"105.3","Single Cell Type RNA - Hepatocytes [nTPM]":"221.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"251.9","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"163.7","Single Cell Type RNA - Ionocytes [nTPM]":"244.1","Single Cell Type RNA - Kupffer cells [nTPM]":"122.0","Single Cell Type RNA - Langerhans cells [nTPM]":"126.3","Single Cell Type RNA - Late spermatids [nTPM]":"62.2","Single Cell Type RNA - Leydig cells [nTPM]":"137.3","Single Cell Type RNA - Macrophages [nTPM]":"131.0","Single Cell Type RNA - Melanocytes [nTPM]":"104.9","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"221.2","Single Cell Type RNA - Muller glia cells [nTPM]":"152.1","Single Cell Type RNA - NK-cells [nTPM]":"157.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"314.0","Single Cell Type RNA - Paneth cells [nTPM]":"130.0","Single Cell Type RNA - Peritubular cells [nTPM]":"123.8","Single Cell Type RNA - Plasma cells [nTPM]":"101.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"166.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"141.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"445.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"178.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"79.1","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"170.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"223.5","Single Cell Type RNA - Spermatocytes [nTPM]":"253.5","Single Cell Type RNA - Spermatogonia [nTPM]":"190.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"136.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"129.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"261.7","Single Cell Type RNA - T-cells [nTPM]":"145.2","Single Cell Type RNA - Theca cells [nTPM]":"254.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"188.1","Single Cell Type RNA - Urothelial cells [nTPM]":"200.2"},{"Gene":"ST3GAL3","Gene synonym":["MRT12","SIAT6"],"Ensembl":"ENSG00000126091","Gene description":"ST3 beta-galactoside alpha-2,3-sialyltransferase 3","Uniprot":["Q11203"],"Chromosome":"1","Position":"43705824-43931165","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"88.0","tongue":"82.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"59.7","Excitatory neurons":"94.4","Granulosa cells":"52.5","Inhibitory neurons":"120.1","Microglial cells":"57.1","Oligodendrocyte precursor cells":"66.9","Oligodendrocytes":"66.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051102"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051102":"AB_2681344"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.9","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"28.5","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"27.3","Tissue RNA - bone marrow [nTPM]":"11.0","Tissue RNA - breast [nTPM]":"11.0","Tissue RNA - cerebellum [nTPM]":"30.8","Tissue RNA - cerebral cortex [nTPM]":"32.5","Tissue RNA - cervix [nTPM]":"14.6","Tissue RNA - choroid plexus [nTPM]":"22.8","Tissue RNA - colon [nTPM]":"19.4","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"16.7","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"8.3","Tissue RNA - fallopian tube [nTPM]":"12.8","Tissue RNA - gallbladder [nTPM]":"6.9","Tissue RNA - heart muscle [nTPM]":"26.1","Tissue RNA - hippocampal formation [nTPM]":"27.2","Tissue RNA - hypothalamus [nTPM]":"29.4","Tissue RNA - kidney [nTPM]":"9.9","Tissue RNA - liver [nTPM]":"13.5","Tissue RNA - lung [nTPM]":"8.7","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"27.9","Tissue RNA - midbrain [nTPM]":"29.0","Tissue RNA - ovary [nTPM]":"14.9","Tissue RNA - pancreas [nTPM]":"8.0","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"17.8","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"29.2","Tissue RNA - prostate [nTPM]":"13.2","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"24.5","Tissue RNA - salivary gland [nTPM]":"8.3","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"88.0","Tissue RNA - skin 1 [nTPM]":"7.0","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"13.1","Tissue RNA - spinal cord [nTPM]":"23.2","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"22.6","Tissue RNA - thalamus [nTPM]":"30.8","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"82.9","Tissue RNA - tonsil [nTPM]":"3.7","Tissue RNA - urinary bladder [nTPM]":"16.7","Tissue RNA - vagina [nTPM]":"10.1","Tissue RNA - white matter [nTPM]":"28.1","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"2.7","Cell RNA - AF22 [nTPM]":"23.4","Cell RNA - AN3-CA [nTPM]":"11.0","Cell RNA - ASC diff [nTPM]":"17.4","Cell RNA - ASC TERT1 [nTPM]":"21.9","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"15.5","Cell RNA - BJ hTERT+ [nTPM]":"30.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.7","Cell RNA - CACO-2 [nTPM]":"2.6","Cell RNA - CAPAN-2 [nTPM]":"6.6","Cell RNA - Daudi [nTPM]":"7.0","Cell RNA - EFO-21 [nTPM]":"8.6","Cell RNA - fHDF\/TERT166 [nTPM]":"19.0","Cell RNA - GAMG [nTPM]":"7.7","Cell RNA - HaCaT [nTPM]":"3.8","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"10.2","Cell RNA - HBF TERT88 [nTPM]":"15.7","Cell RNA - HDLM-2 [nTPM]":"8.7","Cell RNA - HEK 293 [nTPM]":"5.8","Cell RNA - HEL [nTPM]":"15.0","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"7.5","Cell RNA - HHSteC [nTPM]":"14.7","Cell RNA - HL-60 [nTPM]":"6.6","Cell RNA - HMC-1 [nTPM]":"7.1","Cell RNA - HSkMC [nTPM]":"12.1","Cell RNA - hTCEpi [nTPM]":"7.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.7","Cell RNA - hTERT-HME1 [nTPM]":"21.3","Cell RNA - hTERT-RPE1 [nTPM]":"26.1","Cell RNA - HUVEC TERT2 [nTPM]":"12.1","Cell RNA - JURKAT [nTPM]":"18.4","Cell RNA - K-562 [nTPM]":"8.8","Cell RNA - Karpas-707 [nTPM]":"13.1","Cell RNA - LHCN-M2 [nTPM]":"25.3","Cell RNA - MCF7 [nTPM]":"2.7","Cell RNA - MOLT-4 [nTPM]":"7.0","Cell RNA - NB-4 [nTPM]":"11.7","Cell RNA - NTERA-2 [nTPM]":"9.2","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"11.4","Cell RNA - RH-30 [nTPM]":"3.3","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"11.0","Cell RNA - RT4 [nTPM]":"2.4","Cell RNA - SCLC-21H [nTPM]":"9.3","Cell RNA - SH-SY5Y [nTPM]":"13.8","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"2.5","Cell RNA - SK-MEL-30 [nTPM]":"14.1","Cell RNA - SuSa [nTPM]":"9.6","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"30.3","Cell RNA - TIME [nTPM]":"10.4","Cell RNA - U-138 MG [nTPM]":"8.3","Cell RNA - U-2 OS [nTPM]":"3.9","Cell RNA - U-2197 [nTPM]":"13.3","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"10.4","Cell RNA - U-266\/84 [nTPM]":"6.1","Cell RNA - U-698 [nTPM]":"6.9","Cell RNA - U-87 MG [nTPM]":"11.7","Cell RNA - U-937 [nTPM]":"15.7","Cell RNA - WM-115 [nTPM]":"15.3","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"28.5","Brain RNA - basal ganglia [nTPM]":"27.3","Brain RNA - cerebellum [nTPM]":"30.8","Brain RNA - cerebral cortex [nTPM]":"32.5","Brain RNA - hippocampal formation [nTPM]":"27.2","Brain RNA - hypothalamus [nTPM]":"29.4","Brain RNA - medulla oblongata [nTPM]":"27.9","Brain RNA - midbrain [nTPM]":"29.0","Brain RNA - pons [nTPM]":"29.2","Brain RNA - spinal cord [nTPM]":"23.2","Brain RNA - thalamus [nTPM]":"30.8","Brain RNA - white matter [nTPM]":"28.1","Single Cell Type RNA - Adipocytes [nTPM]":"6.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.3","Single Cell Type RNA - Astrocytes [nTPM]":"59.7","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"9.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.6","Single Cell Type RNA - Early spermatids [nTPM]":"19.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"94.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.6","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"52.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"8.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"120.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.4","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"14.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"4.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"57.1","Single Cell Type RNA - monocytes [nTPM]":"3.6","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"66.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"8.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"6.0","Single Cell Type RNA - Theca cells [nTPM]":"15.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"10.0"},{"Gene":"ST3GAL5","Gene synonym":["SIAT9","SIATGM3S","ST3GalV"],"Ensembl":"ENSG00000115525","Gene description":"ST3 beta-galactoside alpha-2,3-sialyltransferase 5","Uniprot":["Q9UNP4"],"Chromosome":"2","Position":"85837120-85905199","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"47.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"112.8","Oligodendrocyte precursor cells":"94.0","Oligodendrocytes":"108.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"41.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"54.4","RT4":"47.0","SK-MEL-30":"40.8","U-266\/84":"42.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034708","HPA040425","HPA068928"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA034708":"AB_10601594","HPA040425":"AB_2676978","HPA068928":"AB_2686060"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.25e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.99e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.48e-4"},"Tissue RNA - adipose tissue [nTPM]":"17.5","Tissue RNA - adrenal gland [nTPM]":"47.4","Tissue RNA - amygdala [nTPM]":"17.1","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"26.9","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"16.4","Tissue RNA - cerebral cortex [nTPM]":"20.1","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"7.9","Tissue RNA - colon [nTPM]":"5.0","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"9.9","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"10.4","Tissue RNA - gallbladder [nTPM]":"8.1","Tissue RNA - heart muscle [nTPM]":"4.2","Tissue RNA - hippocampal formation [nTPM]":"16.0","Tissue RNA - hypothalamus [nTPM]":"24.7","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"9.8","Tissue RNA - lung [nTPM]":"14.6","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"24.7","Tissue RNA - midbrain [nTPM]":"22.6","Tissue RNA - ovary [nTPM]":"10.1","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"12.8","Tissue RNA - placenta [nTPM]":"17.7","Tissue RNA - pons [nTPM]":"23.1","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"31.0","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"12.4","Tissue RNA - skin 1 [nTPM]":"6.1","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"20.6","Tissue RNA - spleen [nTPM]":"20.0","Tissue RNA - stomach 1 [nTPM]":"5.6","Tissue RNA - testis [nTPM]":"10.8","Tissue RNA - thalamus [nTPM]":"23.6","Tissue RNA - thymus [nTPM]":"5.0","Tissue RNA - thyroid gland [nTPM]":"27.9","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"20.8","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"41.6","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"27.0","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"54.4","Cell RNA - ASC diff [nTPM]":"22.0","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"8.0","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"19.6","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"2.5","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"3.6","Cell RNA - HBEC3-KT [nTPM]":"6.4","Cell RNA - HBF TERT88 [nTPM]":"7.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"3.2","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"17.6","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"6.9","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.1","Cell RNA - hTERT-HME1 [nTPM]":"0.8","Cell RNA - hTERT-RPE1 [nTPM]":"10.1","Cell RNA - HUVEC TERT2 [nTPM]":"13.7","Cell RNA - JURKAT [nTPM]":"7.4","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"30.2","Cell RNA - LHCN-M2 [nTPM]":"18.3","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"3.1","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"9.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"3.5","Cell RNA - RH-30 [nTPM]":"17.0","Cell RNA - RPMI-8226 [nTPM]":"11.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"47.0","Cell RNA - SCLC-21H [nTPM]":"3.8","Cell RNA - SH-SY5Y [nTPM]":"3.8","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"40.8","Cell RNA - SuSa [nTPM]":"5.4","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"2.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"30.0","Cell RNA - U-266\/84 [nTPM]":"42.5","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"4.2","Cell RNA - U-937 [nTPM]":"5.6","Cell RNA - WM-115 [nTPM]":"27.7","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"2.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"17.1","Brain RNA - basal ganglia [nTPM]":"26.9","Brain RNA - cerebellum [nTPM]":"16.4","Brain RNA - cerebral cortex [nTPM]":"20.1","Brain RNA - hippocampal formation [nTPM]":"16.0","Brain RNA - hypothalamus [nTPM]":"24.7","Brain RNA - medulla oblongata [nTPM]":"24.7","Brain RNA - midbrain [nTPM]":"22.6","Brain RNA - pons [nTPM]":"23.1","Brain RNA - spinal cord [nTPM]":"20.6","Brain RNA - thalamus [nTPM]":"23.6","Brain RNA - white matter [nTPM]":"41.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"112.8","Single Cell Type RNA - Astrocytes [nTPM]":"37.5","Single Cell Type RNA - B-cells [nTPM]":"29.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"56.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"33.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"48.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.8","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"21.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"34.8","Single Cell Type RNA - Granulosa cells [nTPM]":"35.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"21.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.6","Single Cell Type RNA - Horizontal cells [nTPM]":"72.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"60.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"45.4","Single Cell Type RNA - Langerhans cells [nTPM]":"18.1","Single Cell Type RNA - Late spermatids [nTPM]":"12.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"24.9","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"20.1","Single Cell Type RNA - Muller glia cells [nTPM]":"56.0","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"94.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"108.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"19.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"45.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.4","Single Cell Type RNA - Spermatogonia [nTPM]":"16.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"28.9","Single Cell Type RNA - Theca cells [nTPM]":"6.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"8.3"},{"Gene":"STARD7","Gene synonym":["GTT1"],"Ensembl":"ENSG00000084090","Gene description":"StAR related lipid transfer domain containing 7","Uniprot":["Q9NQZ5"],"Chromosome":"2","Position":"96184859-96208827","Protein class":["Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033965","HPA064958","HPA064978"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB033965":"AB_2302780","HPA064958":"AB_2685391","HPA064978":"AB_2685397"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.56e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.89e-6"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.38e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"44.7","Tissue RNA - adrenal gland [nTPM]":"54.3","Tissue RNA - amygdala [nTPM]":"57.8","Tissue RNA - appendix [nTPM]":"46.7","Tissue RNA - basal ganglia [nTPM]":"62.4","Tissue RNA - bone marrow [nTPM]":"34.3","Tissue RNA - breast [nTPM]":"43.9","Tissue RNA - cerebellum [nTPM]":"61.9","Tissue RNA - cerebral cortex [nTPM]":"53.2","Tissue RNA - cervix [nTPM]":"33.9","Tissue RNA - choroid plexus [nTPM]":"60.6","Tissue RNA - colon [nTPM]":"57.6","Tissue RNA - duodenum [nTPM]":"55.7","Tissue RNA - endometrium 1 [nTPM]":"29.8","Tissue RNA - epididymis [nTPM]":"30.5","Tissue RNA - esophagus [nTPM]":"36.8","Tissue RNA - fallopian tube [nTPM]":"44.0","Tissue RNA - gallbladder [nTPM]":"29.1","Tissue RNA - heart muscle [nTPM]":"98.5","Tissue RNA - hippocampal formation [nTPM]":"49.8","Tissue RNA - hypothalamus [nTPM]":"61.4","Tissue RNA - kidney [nTPM]":"80.3","Tissue RNA - liver [nTPM]":"62.8","Tissue RNA - lung [nTPM]":"61.1","Tissue RNA - lymph node [nTPM]":"70.6","Tissue RNA - medulla oblongata [nTPM]":"56.4","Tissue RNA - midbrain [nTPM]":"55.5","Tissue RNA - ovary [nTPM]":"29.4","Tissue RNA - pancreas [nTPM]":"42.2","Tissue RNA - parathyroid gland [nTPM]":"69.7","Tissue RNA - pituitary gland [nTPM]":"23.6","Tissue RNA - placenta [nTPM]":"29.3","Tissue RNA - pons [nTPM]":"54.9","Tissue RNA - prostate [nTPM]":"39.0","Tissue RNA - rectum [nTPM]":"56.2","Tissue RNA - retina [nTPM]":"54.4","Tissue RNA - salivary gland [nTPM]":"65.2","Tissue RNA - seminal vesicle [nTPM]":"45.7","Tissue RNA - skeletal muscle [nTPM]":"202.5","Tissue RNA - skin 1 [nTPM]":"35.2","Tissue RNA - small intestine [nTPM]":"45.4","Tissue RNA - smooth muscle [nTPM]":"37.6","Tissue RNA - spinal cord [nTPM]":"60.5","Tissue RNA - spleen [nTPM]":"53.1","Tissue RNA - stomach 1 [nTPM]":"44.6","Tissue RNA - testis [nTPM]":"21.1","Tissue RNA - thalamus [nTPM]":"66.9","Tissue RNA - thymus [nTPM]":"56.2","Tissue RNA - thyroid gland [nTPM]":"56.6","Tissue RNA - tongue [nTPM]":"174.0","Tissue RNA - tonsil [nTPM]":"86.9","Tissue RNA - urinary bladder [nTPM]":"42.1","Tissue RNA - vagina [nTPM]":"27.0","Tissue RNA - white matter [nTPM]":"74.4","Cell RNA - A-431 [nTPM]":"128.8","Cell RNA - A549 [nTPM]":"79.1","Cell RNA - AF22 [nTPM]":"102.3","Cell RNA - AN3-CA [nTPM]":"106.2","Cell RNA - ASC diff [nTPM]":"134.9","Cell RNA - ASC TERT1 [nTPM]":"66.9","Cell RNA - BEWO [nTPM]":"150.1","Cell RNA - BJ [nTPM]":"122.6","Cell RNA - BJ hTERT+ [nTPM]":"107.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"121.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"129.6","Cell RNA - CACO-2 [nTPM]":"188.8","Cell RNA - CAPAN-2 [nTPM]":"117.7","Cell RNA - Daudi [nTPM]":"228.7","Cell RNA - EFO-21 [nTPM]":"129.0","Cell RNA - fHDF\/TERT166 [nTPM]":"98.6","Cell RNA - GAMG [nTPM]":"95.8","Cell RNA - HaCaT [nTPM]":"102.3","Cell RNA - HAP1 [nTPM]":"183.3","Cell RNA - HBEC3-KT [nTPM]":"106.4","Cell RNA - HBF TERT88 [nTPM]":"157.3","Cell RNA - HDLM-2 [nTPM]":"147.2","Cell RNA - HEK 293 [nTPM]":"131.9","Cell RNA - HEL [nTPM]":"204.1","Cell RNA - HeLa [nTPM]":"74.3","Cell RNA - Hep G2 [nTPM]":"218.3","Cell RNA - HHSteC [nTPM]":"62.2","Cell RNA - HL-60 [nTPM]":"158.1","Cell RNA - HMC-1 [nTPM]":"106.9","Cell RNA - HSkMC [nTPM]":"65.4","Cell RNA - hTCEpi [nTPM]":"77.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"101.0","Cell RNA - hTERT-HME1 [nTPM]":"99.1","Cell RNA - hTERT-RPE1 [nTPM]":"77.2","Cell RNA - HUVEC TERT2 [nTPM]":"123.2","Cell RNA - JURKAT [nTPM]":"92.6","Cell RNA - K-562 [nTPM]":"211.1","Cell RNA - Karpas-707 [nTPM]":"89.2","Cell RNA - LHCN-M2 [nTPM]":"108.8","Cell RNA - MCF7 [nTPM]":"113.0","Cell RNA - MOLT-4 [nTPM]":"175.9","Cell RNA - NB-4 [nTPM]":"161.0","Cell RNA - NTERA-2 [nTPM]":"173.3","Cell RNA - OE19 [nTPM]":"110.3","Cell RNA - PC-3 [nTPM]":"115.2","Cell RNA - REH [nTPM]":"171.6","Cell RNA - RH-30 [nTPM]":"156.4","Cell RNA - RPMI-8226 [nTPM]":"227.1","Cell RNA - RPTEC TERT1 [nTPM]":"73.2","Cell RNA - RT4 [nTPM]":"162.2","Cell RNA - SCLC-21H [nTPM]":"191.6","Cell RNA - SH-SY5Y [nTPM]":"90.5","Cell RNA - SiHa [nTPM]":"62.5","Cell RNA - SK-BR-3 [nTPM]":"201.8","Cell RNA - SK-MEL-30 [nTPM]":"115.8","Cell RNA - SuSa [nTPM]":"126.0","Cell RNA - T-47d [nTPM]":"60.5","Cell RNA - THP-1 [nTPM]":"171.6","Cell RNA - TIME [nTPM]":"103.8","Cell RNA - U-138 MG [nTPM]":"100.1","Cell RNA - U-2 OS [nTPM]":"100.4","Cell RNA - U-2197 [nTPM]":"112.0","Cell RNA - U-251 MG [nTPM]":"125.8","Cell RNA - U-266\/70 [nTPM]":"113.9","Cell RNA - U-266\/84 [nTPM]":"114.0","Cell RNA - U-698 [nTPM]":"201.7","Cell RNA - U-87 MG [nTPM]":"92.8","Cell RNA - U-937 [nTPM]":"174.9","Cell RNA - WM-115 [nTPM]":"112.6","Blood RNA - basophil [nTPM]":"35.6","Blood RNA - classical monocyte [nTPM]":"25.4","Blood RNA - eosinophil [nTPM]":"22.7","Blood RNA - gdT-cell [nTPM]":"25.6","Blood RNA - intermediate monocyte [nTPM]":"30.2","Blood RNA - MAIT T-cell [nTPM]":"26.1","Blood RNA - memory B-cell [nTPM]":"42.6","Blood RNA - memory CD4 T-cell [nTPM]":"21.5","Blood RNA - memory CD8 T-cell [nTPM]":"26.6","Blood RNA - myeloid DC [nTPM]":"36.2","Blood RNA - naive B-cell [nTPM]":"37.8","Blood RNA - naive CD4 T-cell [nTPM]":"23.6","Blood RNA - naive CD8 T-cell [nTPM]":"23.4","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"30.8","Blood RNA - non-classical monocyte [nTPM]":"19.9","Blood RNA - plasmacytoid DC [nTPM]":"42.2","Blood RNA - T-reg [nTPM]":"41.5","Blood RNA - total PBMC [nTPM]":"26.0","Brain RNA - amygdala [nTPM]":"57.8","Brain RNA - basal ganglia [nTPM]":"62.4","Brain RNA - cerebellum [nTPM]":"61.9","Brain RNA - cerebral cortex [nTPM]":"53.2","Brain RNA - hippocampal formation [nTPM]":"49.8","Brain RNA - hypothalamus [nTPM]":"61.4","Brain RNA - medulla oblongata [nTPM]":"56.4","Brain RNA - midbrain [nTPM]":"55.5","Brain RNA - pons [nTPM]":"54.9","Brain RNA - spinal cord [nTPM]":"60.5","Brain RNA - thalamus [nTPM]":"66.9","Brain RNA - white matter [nTPM]":"74.4","Single Cell Type RNA - Adipocytes [nTPM]":"32.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"134.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"44.2","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"71.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"63.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"101.9","Single Cell Type RNA - Bipolar cells [nTPM]":"39.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"176.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"55.8","Single Cell Type RNA - Club cells [nTPM]":"47.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"108.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.8","Single Cell Type RNA - dendritic cells [nTPM]":"83.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"63.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"32.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.2","Single Cell Type RNA - Endothelial cells [nTPM]":"49.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.4","Single Cell Type RNA - Erythroid cells [nTPM]":"48.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.3","Single Cell Type RNA - Fibroblasts [nTPM]":"31.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.6","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"45.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.7","Single Cell Type RNA - Hepatocytes [nTPM]":"114.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"71.0","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"58.4","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"122.4","Single Cell Type RNA - Langerhans cells [nTPM]":"102.3","Single Cell Type RNA - Late spermatids [nTPM]":"6.9","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"54.4","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"95.8","Single Cell Type RNA - Muller glia cells [nTPM]":"38.4","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.8","Single Cell Type RNA - Paneth cells [nTPM]":"26.6","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"120.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"68.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"65.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.0","Single Cell Type RNA - Spermatocytes [nTPM]":"22.7","Single Cell Type RNA - Spermatogonia [nTPM]":"35.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"75.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"57.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.4","Single Cell Type RNA - T-cells [nTPM]":"62.9","Single Cell Type RNA - Theca cells [nTPM]":"36.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"81.9","Single Cell Type RNA - Urothelial cells [nTPM]":"38.8"},{"Gene":"STN1","Gene synonym":["bA541N10.2","FLJ22559","OBFC1"],"Ensembl":"ENSG00000107960","Gene description":"STN1 subunit of CST complex","Uniprot":["Q9H668"],"Chromosome":"10","Position":"103877569-103918184","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"37.4","Distal tubular cells":"41.1","Ductal cells":"34.6","Exocrine glandular cells":"79.2","Pancreatic endocrine cells":"62.9","Theca cells":"52.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037924","HPA037925"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA037924":"AB_10671636","HPA037925":"AB_10672469"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.7","Tissue RNA - adrenal gland [nTPM]":"22.2","Tissue RNA - amygdala [nTPM]":"8.8","Tissue RNA - appendix [nTPM]":"12.2","Tissue RNA - basal ganglia [nTPM]":"10.1","Tissue RNA - bone marrow [nTPM]":"13.5","Tissue RNA - breast [nTPM]":"17.1","Tissue RNA - cerebellum [nTPM]":"11.3","Tissue RNA - cerebral cortex [nTPM]":"9.4","Tissue RNA - cervix [nTPM]":"13.3","Tissue RNA - choroid plexus [nTPM]":"11.5","Tissue RNA - colon [nTPM]":"14.5","Tissue RNA - duodenum [nTPM]":"12.0","Tissue RNA - endometrium 1 [nTPM]":"12.0","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"41.0","Tissue RNA - fallopian tube [nTPM]":"12.2","Tissue RNA - gallbladder [nTPM]":"18.3","Tissue RNA - heart muscle [nTPM]":"35.0","Tissue RNA - hippocampal formation [nTPM]":"8.2","Tissue RNA - hypothalamus [nTPM]":"11.1","Tissue RNA - kidney [nTPM]":"17.9","Tissue RNA - liver [nTPM]":"13.1","Tissue RNA - lung [nTPM]":"25.2","Tissue RNA - lymph node [nTPM]":"16.0","Tissue RNA - medulla oblongata [nTPM]":"13.1","Tissue RNA - midbrain [nTPM]":"11.0","Tissue RNA - ovary [nTPM]":"22.2","Tissue RNA - pancreas [nTPM]":"20.9","Tissue RNA - parathyroid gland [nTPM]":"33.6","Tissue RNA - pituitary gland [nTPM]":"14.9","Tissue RNA - placenta [nTPM]":"17.1","Tissue RNA - pons [nTPM]":"11.5","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"16.4","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"18.7","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"22.4","Tissue RNA - skin 1 [nTPM]":"13.3","Tissue RNA - small intestine [nTPM]":"11.0","Tissue RNA - smooth muscle [nTPM]":"15.4","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"15.3","Tissue RNA - stomach 1 [nTPM]":"22.2","Tissue RNA - testis [nTPM]":"23.4","Tissue RNA - thalamus [nTPM]":"11.5","Tissue RNA - thymus [nTPM]":"24.5","Tissue RNA - thyroid gland [nTPM]":"17.6","Tissue RNA - tongue [nTPM]":"28.9","Tissue RNA - tonsil [nTPM]":"22.8","Tissue RNA - urinary bladder [nTPM]":"22.5","Tissue RNA - vagina [nTPM]":"18.5","Tissue RNA - white matter [nTPM]":"11.2","Cell RNA - A-431 [nTPM]":"26.8","Cell RNA - A549 [nTPM]":"19.7","Cell RNA - AF22 [nTPM]":"23.8","Cell RNA - AN3-CA [nTPM]":"19.6","Cell RNA - ASC diff [nTPM]":"18.6","Cell RNA - ASC TERT1 [nTPM]":"57.6","Cell RNA - BEWO [nTPM]":"7.6","Cell RNA - BJ [nTPM]":"12.6","Cell RNA - BJ hTERT+ [nTPM]":"36.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.6","Cell RNA - CACO-2 [nTPM]":"11.4","Cell RNA - CAPAN-2 [nTPM]":"43.6","Cell RNA - Daudi [nTPM]":"16.7","Cell RNA - EFO-21 [nTPM]":"22.2","Cell RNA - fHDF\/TERT166 [nTPM]":"16.1","Cell RNA - GAMG [nTPM]":"14.7","Cell RNA - HaCaT [nTPM]":"24.8","Cell RNA - HAP1 [nTPM]":"8.7","Cell RNA - HBEC3-KT [nTPM]":"31.0","Cell RNA - HBF TERT88 [nTPM]":"15.3","Cell RNA - HDLM-2 [nTPM]":"24.1","Cell RNA - HEK 293 [nTPM]":"11.9","Cell RNA - HEL [nTPM]":"15.3","Cell RNA - HeLa [nTPM]":"7.0","Cell RNA - Hep G2 [nTPM]":"23.5","Cell RNA - HHSteC [nTPM]":"25.6","Cell RNA - HL-60 [nTPM]":"12.7","Cell RNA - HMC-1 [nTPM]":"12.9","Cell RNA - HSkMC [nTPM]":"37.2","Cell RNA - hTCEpi [nTPM]":"52.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.9","Cell RNA - hTERT-HME1 [nTPM]":"43.9","Cell RNA - hTERT-RPE1 [nTPM]":"42.9","Cell RNA - HUVEC TERT2 [nTPM]":"32.0","Cell RNA - JURKAT [nTPM]":"31.2","Cell RNA - K-562 [nTPM]":"8.5","Cell RNA - Karpas-707 [nTPM]":"34.9","Cell RNA - LHCN-M2 [nTPM]":"27.3","Cell RNA - MCF7 [nTPM]":"21.7","Cell RNA - MOLT-4 [nTPM]":"31.5","Cell RNA - NB-4 [nTPM]":"22.0","Cell RNA - NTERA-2 [nTPM]":"5.5","Cell RNA - OE19 [nTPM]":"38.7","Cell RNA - PC-3 [nTPM]":"28.5","Cell RNA - REH [nTPM]":"22.7","Cell RNA - RH-30 [nTPM]":"16.4","Cell RNA - RPMI-8226 [nTPM]":"19.2","Cell RNA - RPTEC TERT1 [nTPM]":"40.5","Cell RNA - RT4 [nTPM]":"31.3","Cell RNA - SCLC-21H [nTPM]":"13.7","Cell RNA - SH-SY5Y [nTPM]":"16.1","Cell RNA - SiHa [nTPM]":"9.3","Cell RNA - SK-BR-3 [nTPM]":"14.9","Cell RNA - SK-MEL-30 [nTPM]":"24.4","Cell RNA - SuSa [nTPM]":"13.4","Cell RNA - T-47d [nTPM]":"12.5","Cell RNA - THP-1 [nTPM]":"11.0","Cell RNA - TIME [nTPM]":"47.1","Cell RNA - U-138 MG [nTPM]":"20.4","Cell RNA - U-2 OS [nTPM]":"14.1","Cell RNA - U-2197 [nTPM]":"14.5","Cell RNA - U-251 MG [nTPM]":"19.4","Cell RNA - U-266\/70 [nTPM]":"47.3","Cell RNA - U-266\/84 [nTPM]":"13.1","Cell RNA - U-698 [nTPM]":"16.6","Cell RNA - U-87 MG [nTPM]":"30.4","Cell RNA - U-937 [nTPM]":"26.4","Cell RNA - WM-115 [nTPM]":"9.0","Blood RNA - basophil [nTPM]":"41.7","Blood RNA - classical monocyte [nTPM]":"33.2","Blood RNA - eosinophil [nTPM]":"110.3","Blood RNA - gdT-cell [nTPM]":"65.1","Blood RNA - intermediate monocyte [nTPM]":"21.3","Blood RNA - MAIT T-cell [nTPM]":"103.4","Blood RNA - memory B-cell [nTPM]":"25.5","Blood RNA - memory CD4 T-cell [nTPM]":"71.9","Blood RNA - memory CD8 T-cell [nTPM]":"60.4","Blood RNA - myeloid DC [nTPM]":"40.2","Blood RNA - naive B-cell [nTPM]":"29.6","Blood RNA - naive CD4 T-cell [nTPM]":"52.3","Blood RNA - naive CD8 T-cell [nTPM]":"62.6","Blood RNA - neutrophil [nTPM]":"48.8","Blood RNA - NK-cell [nTPM]":"71.3","Blood RNA - non-classical monocyte [nTPM]":"23.7","Blood RNA - plasmacytoid DC [nTPM]":"37.1","Blood RNA - T-reg [nTPM]":"100.2","Blood RNA - total PBMC [nTPM]":"51.5","Brain RNA - amygdala [nTPM]":"8.8","Brain RNA - basal ganglia [nTPM]":"10.1","Brain RNA - cerebellum [nTPM]":"11.3","Brain RNA - cerebral cortex [nTPM]":"9.4","Brain RNA - hippocampal formation [nTPM]":"8.2","Brain RNA - hypothalamus [nTPM]":"11.1","Brain RNA - medulla oblongata [nTPM]":"13.1","Brain RNA - midbrain [nTPM]":"11.0","Brain RNA - pons [nTPM]":"11.5","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"11.5","Brain RNA - white matter [nTPM]":"11.2","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.4","Single Cell Type RNA - dendritic cells [nTPM]":"17.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"34.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.9","Single Cell Type RNA - Endothelial cells [nTPM]":"6.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"79.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.4","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"23.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"6.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"13.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"62.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.0","Single Cell Type RNA - T-cells [nTPM]":"13.3","Single Cell Type RNA - Theca cells [nTPM]":"52.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"STRC","Gene synonym":["DFNB16"],"Ensembl":"ENSG00000242866","Gene description":"Stereocilin","Uniprot":["Q7RTU9"],"Chromosome":"15","Position":"43599563-43618800","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"9.0","pituitary gland":"4.4","retina":"3.6","testis":"5.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"10.1","Excitatory neurons":"55.7","Inhibitory neurons":"35.4","Oligodendrocyte precursor cells":"13.0","Oligodendrocytes":"15.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048083"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048083":"AB_2732545"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"9.0","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"2.4","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"4.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"3.6","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.5","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"5.0","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"4.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"9.0","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"2.4","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"1.5","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"4.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"55.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"4.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"STUB1","Gene synonym":["CHIP","HSPABP2","NY-CO-7","SDCCAG7","UBOX1"],"Ensembl":"ENSG00000103266","Gene description":"STIP1 homology and U-box containing protein 1","Uniprot":["Q9UNE7"],"Chromosome":"16","Position":"680224-682870","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037202","CAB037209","HPA041222","HPA043531"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB037202":"AB_1840759","CAB037209":"AB_1840757","HPA041222":"AB_2677368","HPA043531":"AB_2678533"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.49e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Tissue RNA - adipose tissue [nTPM]":"80.2","Tissue RNA - adrenal gland [nTPM]":"126.3","Tissue RNA - amygdala [nTPM]":"185.5","Tissue RNA - appendix [nTPM]":"35.6","Tissue RNA - basal ganglia [nTPM]":"186.9","Tissue RNA - bone marrow [nTPM]":"48.9","Tissue RNA - breast [nTPM]":"76.0","Tissue RNA - cerebellum [nTPM]":"183.8","Tissue RNA - cerebral cortex [nTPM]":"242.7","Tissue RNA - cervix [nTPM]":"74.8","Tissue RNA - choroid plexus [nTPM]":"173.1","Tissue RNA - colon [nTPM]":"100.3","Tissue RNA - duodenum [nTPM]":"50.7","Tissue RNA - endometrium 1 [nTPM]":"67.0","Tissue RNA - epididymis [nTPM]":"60.3","Tissue RNA - esophagus [nTPM]":"86.8","Tissue RNA - fallopian tube [nTPM]":"65.3","Tissue RNA - gallbladder [nTPM]":"42.1","Tissue RNA - heart muscle [nTPM]":"151.1","Tissue RNA - hippocampal formation [nTPM]":"187.3","Tissue RNA - hypothalamus [nTPM]":"185.3","Tissue RNA - kidney [nTPM]":"91.4","Tissue RNA - liver [nTPM]":"100.7","Tissue RNA - lung [nTPM]":"65.0","Tissue RNA - lymph node [nTPM]":"52.5","Tissue RNA - medulla oblongata [nTPM]":"188.2","Tissue RNA - midbrain [nTPM]":"184.2","Tissue RNA - ovary [nTPM]":"65.7","Tissue RNA - pancreas [nTPM]":"93.7","Tissue RNA - parathyroid gland [nTPM]":"90.6","Tissue RNA - pituitary gland [nTPM]":"93.7","Tissue RNA - placenta [nTPM]":"23.9","Tissue RNA - pons [nTPM]":"187.9","Tissue RNA - prostate [nTPM]":"80.2","Tissue RNA - rectum [nTPM]":"32.6","Tissue RNA - retina [nTPM]":"33.2","Tissue RNA - salivary gland [nTPM]":"86.6","Tissue RNA - seminal vesicle [nTPM]":"53.5","Tissue RNA - skeletal muscle [nTPM]":"201.8","Tissue RNA - skin 1 [nTPM]":"111.7","Tissue RNA - small intestine [nTPM]":"63.1","Tissue RNA - smooth muscle [nTPM]":"40.1","Tissue RNA - spinal cord [nTPM]":"180.6","Tissue RNA - spleen [nTPM]":"70.0","Tissue RNA - stomach 1 [nTPM]":"86.2","Tissue RNA - testis [nTPM]":"45.1","Tissue RNA - thalamus [nTPM]":"193.5","Tissue RNA - thymus [nTPM]":"42.3","Tissue RNA - thyroid gland [nTPM]":"72.9","Tissue RNA - tongue [nTPM]":"125.2","Tissue RNA - tonsil [nTPM]":"38.2","Tissue RNA - urinary bladder [nTPM]":"80.7","Tissue RNA - vagina [nTPM]":"69.1","Tissue RNA - white matter [nTPM]":"188.0","Cell RNA - A-431 [nTPM]":"81.6","Cell RNA - A549 [nTPM]":"107.6","Cell RNA - AF22 [nTPM]":"59.4","Cell RNA - AN3-CA [nTPM]":"108.0","Cell RNA - ASC diff [nTPM]":"123.4","Cell RNA - ASC TERT1 [nTPM]":"102.5","Cell RNA - BEWO [nTPM]":"43.8","Cell RNA - BJ [nTPM]":"112.8","Cell RNA - BJ hTERT+ [nTPM]":"95.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"100.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"90.5","Cell RNA - CACO-2 [nTPM]":"131.0","Cell RNA - CAPAN-2 [nTPM]":"97.1","Cell RNA - Daudi [nTPM]":"83.0","Cell RNA - EFO-21 [nTPM]":"78.2","Cell RNA - fHDF\/TERT166 [nTPM]":"147.5","Cell RNA - GAMG [nTPM]":"69.1","Cell RNA - HaCaT [nTPM]":"69.7","Cell RNA - HAP1 [nTPM]":"73.0","Cell RNA - HBEC3-KT [nTPM]":"137.3","Cell RNA - HBF TERT88 [nTPM]":"42.9","Cell RNA - HDLM-2 [nTPM]":"93.6","Cell RNA - HEK 293 [nTPM]":"318.8","Cell RNA - HEL [nTPM]":"53.4","Cell RNA - HeLa [nTPM]":"154.1","Cell RNA - Hep G2 [nTPM]":"104.7","Cell RNA - HHSteC [nTPM]":"183.7","Cell RNA - HL-60 [nTPM]":"85.9","Cell RNA - HMC-1 [nTPM]":"96.4","Cell RNA - HSkMC [nTPM]":"141.1","Cell RNA - hTCEpi [nTPM]":"134.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"118.2","Cell RNA - hTERT-HME1 [nTPM]":"71.4","Cell RNA - hTERT-RPE1 [nTPM]":"76.3","Cell RNA - HUVEC TERT2 [nTPM]":"106.2","Cell RNA - JURKAT [nTPM]":"72.3","Cell RNA - K-562 [nTPM]":"87.1","Cell RNA - Karpas-707 [nTPM]":"119.2","Cell RNA - LHCN-M2 [nTPM]":"149.3","Cell RNA - MCF7 [nTPM]":"318.4","Cell RNA - MOLT-4 [nTPM]":"90.1","Cell RNA - NB-4 [nTPM]":"85.4","Cell RNA - NTERA-2 [nTPM]":"76.4","Cell RNA - OE19 [nTPM]":"107.1","Cell RNA - PC-3 [nTPM]":"127.5","Cell RNA - REH [nTPM]":"143.5","Cell RNA - RH-30 [nTPM]":"46.8","Cell RNA - RPMI-8226 [nTPM]":"200.6","Cell RNA - RPTEC TERT1 [nTPM]":"132.5","Cell RNA - RT4 [nTPM]":"72.6","Cell RNA - SCLC-21H [nTPM]":"121.1","Cell RNA - SH-SY5Y [nTPM]":"103.4","Cell RNA - SiHa [nTPM]":"89.4","Cell RNA - SK-BR-3 [nTPM]":"165.8","Cell RNA - SK-MEL-30 [nTPM]":"137.1","Cell RNA - SuSa [nTPM]":"35.9","Cell RNA - T-47d [nTPM]":"114.1","Cell RNA - THP-1 [nTPM]":"147.8","Cell RNA - TIME [nTPM]":"108.7","Cell RNA - U-138 MG [nTPM]":"104.3","Cell RNA - U-2 OS [nTPM]":"99.8","Cell RNA - U-2197 [nTPM]":"94.3","Cell RNA - U-251 MG [nTPM]":"125.9","Cell RNA - U-266\/70 [nTPM]":"137.6","Cell RNA - U-266\/84 [nTPM]":"150.2","Cell RNA - U-698 [nTPM]":"132.3","Cell RNA - U-87 MG [nTPM]":"83.8","Cell RNA - U-937 [nTPM]":"73.9","Cell RNA - WM-115 [nTPM]":"122.0","Blood RNA - basophil [nTPM]":"17.7","Blood RNA - classical monocyte [nTPM]":"13.6","Blood RNA - eosinophil [nTPM]":"21.7","Blood RNA - gdT-cell [nTPM]":"15.7","Blood RNA - intermediate monocyte [nTPM]":"12.9","Blood RNA - MAIT T-cell [nTPM]":"14.5","Blood RNA - memory B-cell [nTPM]":"19.6","Blood RNA - memory CD4 T-cell [nTPM]":"13.5","Blood RNA - memory CD8 T-cell [nTPM]":"13.8","Blood RNA - myeloid DC [nTPM]":"12.1","Blood RNA - naive B-cell [nTPM]":"21.0","Blood RNA - naive CD4 T-cell [nTPM]":"12.8","Blood RNA - naive CD8 T-cell [nTPM]":"11.6","Blood RNA - neutrophil [nTPM]":"13.4","Blood RNA - NK-cell [nTPM]":"11.2","Blood RNA - non-classical monocyte [nTPM]":"13.9","Blood RNA - plasmacytoid DC [nTPM]":"20.7","Blood RNA - T-reg [nTPM]":"13.2","Blood RNA - total PBMC [nTPM]":"7.2","Brain RNA - amygdala [nTPM]":"185.5","Brain RNA - basal ganglia [nTPM]":"186.9","Brain RNA - cerebellum [nTPM]":"183.8","Brain RNA - cerebral cortex [nTPM]":"242.7","Brain RNA - hippocampal formation [nTPM]":"187.3","Brain RNA - hypothalamus [nTPM]":"185.3","Brain RNA - medulla oblongata [nTPM]":"188.2","Brain RNA - midbrain [nTPM]":"184.2","Brain RNA - pons [nTPM]":"187.9","Brain RNA - spinal cord [nTPM]":"180.6","Brain RNA - thalamus [nTPM]":"193.5","Brain RNA - white matter [nTPM]":"188.0","Single Cell Type RNA - Adipocytes [nTPM]":"96.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.9","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"88.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"114.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"107.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"83.1","Single Cell Type RNA - Bipolar cells [nTPM]":"93.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"137.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"158.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"104.4","Single Cell Type RNA - Club cells [nTPM]":"52.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"130.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"80.1","Single Cell Type RNA - dendritic cells [nTPM]":"101.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"142.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"285.7","Single Cell Type RNA - Ductal cells [nTPM]":"139.6","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"82.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"69.6","Single Cell Type RNA - Endothelial cells [nTPM]":"71.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"76.0","Single Cell Type RNA - Erythroid cells [nTPM]":"68.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"169.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"93.8","Single Cell Type RNA - Fibroblasts [nTPM]":"85.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"68.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"65.0","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"97.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"80.3","Single Cell Type RNA - Hepatocytes [nTPM]":"122.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"113.1","Single Cell Type RNA - Horizontal cells [nTPM]":"84.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"101.4","Single Cell Type RNA - Ionocytes [nTPM]":"85.5","Single Cell Type RNA - Kupffer cells [nTPM]":"69.4","Single Cell Type RNA - Langerhans cells [nTPM]":"94.9","Single Cell Type RNA - Late spermatids [nTPM]":"16.7","Single Cell Type RNA - Leydig cells [nTPM]":"109.0","Single Cell Type RNA - Macrophages [nTPM]":"79.0","Single Cell Type RNA - Melanocytes [nTPM]":"117.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"154.4","Single Cell Type RNA - Muller glia cells [nTPM]":"184.3","Single Cell Type RNA - NK-cells [nTPM]":"110.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"190.2","Single Cell Type RNA - Paneth cells [nTPM]":"110.8","Single Cell Type RNA - Peritubular cells [nTPM]":"112.1","Single Cell Type RNA - Plasma cells [nTPM]":"108.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"160.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"165.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"324.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"61.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"83.9","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"82.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"129.7","Single Cell Type RNA - Spermatocytes [nTPM]":"50.4","Single Cell Type RNA - Spermatogonia [nTPM]":"62.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"107.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"120.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"100.7","Single Cell Type RNA - T-cells [nTPM]":"96.2","Single Cell Type RNA - Theca cells [nTPM]":"132.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"109.3","Single Cell Type RNA - Urothelial cells [nTPM]":"118.8"},{"Gene":"STX1B","Gene synonym":["STX1B1","STX1B2"],"Ensembl":"ENSG00000099365","Gene description":"Syntaxin 1B","Uniprot":["P61266"],"Chromosome":"16","Position":"30989256-31010638","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"137.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"36.8","Horizontal cells":"38.7","Inhibitory neurons":"31.1","Late spermatids":"13.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"5.1"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"137.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+ RasG12V":"9.0","hTEC\/SVTERT24-B":"11.1","hTERT-RPE1":"20.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069176","CAB079008"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"CAB079008":null,"HPA069176":"AB_2686098"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"7.0","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"13.1","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"20.0","Tissue RNA - cerebral cortex [nTPM]":"137.2","Tissue RNA - cervix [nTPM]":"1.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.5","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"3.0","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"15.9","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"5.9","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"51.2","Tissue RNA - midbrain [nTPM]":"5.5","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"42.9","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"3.3","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"4.6","Tissue RNA - thalamus [nTPM]":"5.8","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"52.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"3.0","Cell RNA - AF22 [nTPM]":"4.7","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"4.2","Cell RNA - BJ hTERT+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"3.4","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"5.6","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"2.1","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"6.1","Cell RNA - HDLM-2 [nTPM]":"2.6","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"2.7","Cell RNA - Hep G2 [nTPM]":"2.4","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"2.9","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.1","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"20.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"5.5","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"7.1","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"6.3","Cell RNA - SH-SY5Y [nTPM]":"4.0","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"3.0","Cell RNA - U-2 OS [nTPM]":"2.4","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"3.3","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.0","Brain RNA - basal ganglia [nTPM]":"13.1","Brain RNA - cerebellum [nTPM]":"20.0","Brain RNA - cerebral cortex [nTPM]":"137.2","Brain RNA - hippocampal formation [nTPM]":"15.9","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"51.2","Brain RNA - midbrain [nTPM]":"5.5","Brain RNA - pons [nTPM]":"42.9","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"5.8","Brain RNA - white matter [nTPM]":"52.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"10.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"5.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"13.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"4.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"STXBP1","Gene synonym":["hUNC18","MUNC18-1","rbSec1","UNC18"],"Ensembl":"ENSG00000136854","Gene description":"Syntaxin binding protein 1","Uniprot":["P61764"],"Chromosome":"9","Position":"127579370-127696027","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"174.5","pituitary gland":"66.4","retina":"214.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"131.0","Cone photoreceptor cells":"156.4","Excitatory neurons":"243.2","Inhibitory neurons":"157.5","Rod photoreceptor cells":"155.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"39.6"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"174.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"144.1","SK-MEL-30":"131.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008209","HPA023483","CAB034434"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034434":"AB_2196699","HPA008209":"AB_1857624","HPA023483":"AB_1857625"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.78e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.47e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.81e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Tissue RNA - adipose tissue [nTPM]":"27.5","Tissue RNA - adrenal gland [nTPM]":"28.8","Tissue RNA - amygdala [nTPM]":"22.8","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"33.2","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"21.0","Tissue RNA - cerebellum [nTPM]":"38.6","Tissue RNA - cerebral cortex [nTPM]":"174.5","Tissue RNA - cervix [nTPM]":"21.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"15.9","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"24.1","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"32.3","Tissue RNA - gallbladder [nTPM]":"11.4","Tissue RNA - heart muscle [nTPM]":"24.0","Tissue RNA - hippocampal formation [nTPM]":"48.3","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"14.1","Tissue RNA - liver [nTPM]":"3.1","Tissue RNA - lung [nTPM]":"32.1","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"48.7","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"25.2","Tissue RNA - pancreas [nTPM]":"24.8","Tissue RNA - parathyroid gland [nTPM]":"15.0","Tissue RNA - pituitary gland [nTPM]":"66.4","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"33.1","Tissue RNA - prostate [nTPM]":"10.5","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"214.2","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"10.4","Tissue RNA - skeletal muscle [nTPM]":"9.0","Tissue RNA - skin 1 [nTPM]":"11.4","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"21.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"10.4","Tissue RNA - stomach 1 [nTPM]":"13.3","Tissue RNA - testis [nTPM]":"9.1","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"20.1","Tissue RNA - tongue [nTPM]":"9.2","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"15.4","Tissue RNA - vagina [nTPM]":"16.4","Tissue RNA - white matter [nTPM]":"27.2","Cell RNA - A-431 [nTPM]":"13.2","Cell RNA - A549 [nTPM]":"27.1","Cell RNA - AF22 [nTPM]":"25.5","Cell RNA - AN3-CA [nTPM]":"28.8","Cell RNA - ASC diff [nTPM]":"56.6","Cell RNA - ASC TERT1 [nTPM]":"48.3","Cell RNA - BEWO [nTPM]":"23.2","Cell RNA - BJ [nTPM]":"45.0","Cell RNA - BJ hTERT+ [nTPM]":"22.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.3","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"15.4","Cell RNA - Daudi [nTPM]":"13.1","Cell RNA - EFO-21 [nTPM]":"24.2","Cell RNA - fHDF\/TERT166 [nTPM]":"29.7","Cell RNA - GAMG [nTPM]":"74.2","Cell RNA - HaCaT [nTPM]":"4.7","Cell RNA - HAP1 [nTPM]":"22.6","Cell RNA - HBEC3-KT [nTPM]":"28.1","Cell RNA - HBF TERT88 [nTPM]":"32.7","Cell RNA - HDLM-2 [nTPM]":"29.8","Cell RNA - HEK 293 [nTPM]":"15.4","Cell RNA - HEL [nTPM]":"17.1","Cell RNA - HeLa [nTPM]":"69.7","Cell RNA - Hep G2 [nTPM]":"4.9","Cell RNA - HHSteC [nTPM]":"28.5","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"14.6","Cell RNA - HSkMC [nTPM]":"36.6","Cell RNA - hTCEpi [nTPM]":"15.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"70.0","Cell RNA - hTERT-HME1 [nTPM]":"33.7","Cell RNA - hTERT-RPE1 [nTPM]":"42.6","Cell RNA - HUVEC TERT2 [nTPM]":"32.2","Cell RNA - JURKAT [nTPM]":"43.4","Cell RNA - K-562 [nTPM]":"17.8","Cell RNA - Karpas-707 [nTPM]":"19.6","Cell RNA - LHCN-M2 [nTPM]":"45.5","Cell RNA - MCF7 [nTPM]":"24.5","Cell RNA - MOLT-4 [nTPM]":"12.5","Cell RNA - NB-4 [nTPM]":"5.2","Cell RNA - NTERA-2 [nTPM]":"21.5","Cell RNA - OE19 [nTPM]":"21.4","Cell RNA - PC-3 [nTPM]":"35.9","Cell RNA - REH [nTPM]":"7.5","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"31.3","Cell RNA - RPTEC TERT1 [nTPM]":"22.0","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"144.1","Cell RNA - SH-SY5Y [nTPM]":"69.9","Cell RNA - SiHa [nTPM]":"72.9","Cell RNA - SK-BR-3 [nTPM]":"37.2","Cell RNA - SK-MEL-30 [nTPM]":"131.9","Cell RNA - SuSa [nTPM]":"22.5","Cell RNA - T-47d [nTPM]":"5.8","Cell RNA - THP-1 [nTPM]":"5.6","Cell RNA - TIME [nTPM]":"47.5","Cell RNA - U-138 MG [nTPM]":"30.0","Cell RNA - U-2 OS [nTPM]":"15.1","Cell RNA - U-2197 [nTPM]":"59.9","Cell RNA - U-251 MG [nTPM]":"17.4","Cell RNA - U-266\/70 [nTPM]":"40.2","Cell RNA - U-266\/84 [nTPM]":"73.2","Cell RNA - U-698 [nTPM]":"17.4","Cell RNA - U-87 MG [nTPM]":"59.2","Cell RNA - U-937 [nTPM]":"18.9","Cell RNA - WM-115 [nTPM]":"28.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"22.8","Brain RNA - basal ganglia [nTPM]":"33.2","Brain RNA - cerebellum [nTPM]":"38.6","Brain RNA - cerebral cortex [nTPM]":"174.5","Brain RNA - hippocampal formation [nTPM]":"48.3","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"48.7","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"33.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"27.2","Single Cell Type RNA - Adipocytes [nTPM]":"24.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"70.7","Single Cell Type RNA - Astrocytes [nTPM]":"34.0","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"131.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"156.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.7","Single Cell Type RNA - Endothelial cells [nTPM]":"28.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.6","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"243.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.9","Single Cell Type RNA - Fibroblasts [nTPM]":"18.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.0","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"5.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.4","Single Cell Type RNA - Horizontal cells [nTPM]":"84.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"157.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"5.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"3.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"27.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"61.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"44.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"155.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.2","Single Cell Type RNA - Spermatocytes [nTPM]":"40.6","Single Cell Type RNA - Spermatogonia [nTPM]":"16.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.5","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"17.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"7.1"},{"Gene":"SURF1","Gene synonym":[],"Ensembl":"ENSG00000148290","Gene description":"SURF1 cytochrome c oxidase assembly factor","Uniprot":["Q15526"],"Chromosome":"9","Position":"133351758-133356676","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Leigh syndrome","Neurodegeneration","Neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033946"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033946":"AB_2302648"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.92e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"41.8","Tissue RNA - adrenal gland [nTPM]":"54.3","Tissue RNA - amygdala [nTPM]":"31.8","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"32.9","Tissue RNA - bone marrow [nTPM]":"16.8","Tissue RNA - breast [nTPM]":"39.9","Tissue RNA - cerebellum [nTPM]":"32.3","Tissue RNA - cerebral cortex [nTPM]":"41.3","Tissue RNA - cervix [nTPM]":"33.6","Tissue RNA - choroid plexus [nTPM]":"34.2","Tissue RNA - colon [nTPM]":"53.8","Tissue RNA - duodenum [nTPM]":"18.8","Tissue RNA - endometrium 1 [nTPM]":"32.8","Tissue RNA - epididymis [nTPM]":"38.5","Tissue RNA - esophagus [nTPM]":"34.9","Tissue RNA - fallopian tube [nTPM]":"34.5","Tissue RNA - gallbladder [nTPM]":"12.7","Tissue RNA - heart muscle [nTPM]":"70.6","Tissue RNA - hippocampal formation [nTPM]":"31.0","Tissue RNA - hypothalamus [nTPM]":"31.8","Tissue RNA - kidney [nTPM]":"59.0","Tissue RNA - liver [nTPM]":"93.1","Tissue RNA - lung [nTPM]":"33.4","Tissue RNA - lymph node [nTPM]":"16.7","Tissue RNA - medulla oblongata [nTPM]":"31.9","Tissue RNA - midbrain [nTPM]":"32.3","Tissue RNA - ovary [nTPM]":"31.7","Tissue RNA - pancreas [nTPM]":"79.4","Tissue RNA - parathyroid gland [nTPM]":"34.8","Tissue RNA - pituitary gland [nTPM]":"41.2","Tissue RNA - placenta [nTPM]":"11.9","Tissue RNA - pons [nTPM]":"31.7","Tissue RNA - prostate [nTPM]":"42.5","Tissue RNA - rectum [nTPM]":"20.8","Tissue RNA - retina [nTPM]":"8.9","Tissue RNA - salivary gland [nTPM]":"42.4","Tissue RNA - seminal vesicle [nTPM]":"21.4","Tissue RNA - skeletal muscle [nTPM]":"80.2","Tissue RNA - skin 1 [nTPM]":"41.4","Tissue RNA - small intestine [nTPM]":"41.1","Tissue RNA - smooth muscle [nTPM]":"13.8","Tissue RNA - spinal cord [nTPM]":"32.1","Tissue RNA - spleen [nTPM]":"39.9","Tissue RNA - stomach 1 [nTPM]":"65.4","Tissue RNA - testis [nTPM]":"33.9","Tissue RNA - thalamus [nTPM]":"33.8","Tissue RNA - thymus [nTPM]":"20.3","Tissue RNA - thyroid gland [nTPM]":"43.7","Tissue RNA - tongue [nTPM]":"41.2","Tissue RNA - tonsil [nTPM]":"21.8","Tissue RNA - urinary bladder [nTPM]":"45.6","Tissue RNA - vagina [nTPM]":"31.8","Tissue RNA - white matter [nTPM]":"32.4","Cell RNA - A-431 [nTPM]":"9.6","Cell RNA - A549 [nTPM]":"21.8","Cell RNA - AF22 [nTPM]":"16.5","Cell RNA - AN3-CA [nTPM]":"23.5","Cell RNA - ASC diff [nTPM]":"39.7","Cell RNA - ASC TERT1 [nTPM]":"22.0","Cell RNA - BEWO [nTPM]":"35.6","Cell RNA - BJ [nTPM]":"11.5","Cell RNA - BJ hTERT+ [nTPM]":"27.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.5","Cell RNA - CACO-2 [nTPM]":"29.6","Cell RNA - CAPAN-2 [nTPM]":"32.6","Cell RNA - Daudi [nTPM]":"13.0","Cell RNA - EFO-21 [nTPM]":"16.3","Cell RNA - fHDF\/TERT166 [nTPM]":"18.2","Cell RNA - GAMG [nTPM]":"27.6","Cell RNA - HaCaT [nTPM]":"27.8","Cell RNA - HAP1 [nTPM]":"20.4","Cell RNA - HBEC3-KT [nTPM]":"27.6","Cell RNA - HBF TERT88 [nTPM]":"15.0","Cell RNA - HDLM-2 [nTPM]":"23.8","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"13.2","Cell RNA - HeLa [nTPM]":"31.5","Cell RNA - Hep G2 [nTPM]":"23.4","Cell RNA - HHSteC [nTPM]":"46.9","Cell RNA - HL-60 [nTPM]":"21.1","Cell RNA - HMC-1 [nTPM]":"13.5","Cell RNA - HSkMC [nTPM]":"26.3","Cell RNA - hTCEpi [nTPM]":"47.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.2","Cell RNA - hTERT-HME1 [nTPM]":"32.1","Cell RNA - hTERT-RPE1 [nTPM]":"23.1","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"33.2","Cell RNA - K-562 [nTPM]":"13.7","Cell RNA - Karpas-707 [nTPM]":"26.3","Cell RNA - LHCN-M2 [nTPM]":"21.0","Cell RNA - MCF7 [nTPM]":"42.4","Cell RNA - MOLT-4 [nTPM]":"26.7","Cell RNA - NB-4 [nTPM]":"21.8","Cell RNA - NTERA-2 [nTPM]":"18.6","Cell RNA - OE19 [nTPM]":"86.9","Cell RNA - PC-3 [nTPM]":"22.1","Cell RNA - REH [nTPM]":"18.2","Cell RNA - RH-30 [nTPM]":"24.7","Cell RNA - RPMI-8226 [nTPM]":"40.8","Cell RNA - RPTEC TERT1 [nTPM]":"31.4","Cell RNA - RT4 [nTPM]":"20.4","Cell RNA - SCLC-21H [nTPM]":"16.2","Cell RNA - SH-SY5Y [nTPM]":"45.0","Cell RNA - SiHa [nTPM]":"26.2","Cell RNA - SK-BR-3 [nTPM]":"34.2","Cell RNA - SK-MEL-30 [nTPM]":"30.6","Cell RNA - SuSa [nTPM]":"22.4","Cell RNA - T-47d [nTPM]":"50.1","Cell RNA - THP-1 [nTPM]":"15.8","Cell RNA - TIME [nTPM]":"12.2","Cell RNA - U-138 MG [nTPM]":"23.3","Cell RNA - U-2 OS [nTPM]":"14.3","Cell RNA - U-2197 [nTPM]":"16.1","Cell RNA - U-251 MG [nTPM]":"11.6","Cell RNA - U-266\/70 [nTPM]":"32.2","Cell RNA - U-266\/84 [nTPM]":"51.9","Cell RNA - U-698 [nTPM]":"16.3","Cell RNA - U-87 MG [nTPM]":"22.1","Cell RNA - U-937 [nTPM]":"10.3","Cell RNA - WM-115 [nTPM]":"24.0","Blood RNA - basophil [nTPM]":"10.7","Blood RNA - classical monocyte [nTPM]":"11.6","Blood RNA - eosinophil [nTPM]":"24.1","Blood RNA - gdT-cell [nTPM]":"6.6","Blood RNA - intermediate monocyte [nTPM]":"7.8","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"23.9","Blood RNA - memory CD4 T-cell [nTPM]":"9.8","Blood RNA - memory CD8 T-cell [nTPM]":"9.0","Blood RNA - myeloid DC [nTPM]":"10.2","Blood RNA - naive B-cell [nTPM]":"19.3","Blood RNA - naive CD4 T-cell [nTPM]":"14.0","Blood RNA - naive CD8 T-cell [nTPM]":"7.7","Blood RNA - neutrophil [nTPM]":"11.1","Blood RNA - NK-cell [nTPM]":"6.5","Blood RNA - non-classical monocyte [nTPM]":"7.1","Blood RNA - plasmacytoid DC [nTPM]":"13.4","Blood RNA - T-reg [nTPM]":"14.9","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"31.8","Brain RNA - basal ganglia [nTPM]":"32.9","Brain RNA - cerebellum [nTPM]":"32.3","Brain RNA - cerebral cortex [nTPM]":"41.3","Brain RNA - hippocampal formation [nTPM]":"31.0","Brain RNA - hypothalamus [nTPM]":"31.8","Brain RNA - medulla oblongata [nTPM]":"31.9","Brain RNA - midbrain [nTPM]":"32.3","Brain RNA - pons [nTPM]":"31.7","Brain RNA - spinal cord [nTPM]":"32.1","Brain RNA - thalamus [nTPM]":"33.8","Brain RNA - white matter [nTPM]":"32.4","Single Cell Type RNA - Adipocytes [nTPM]":"46.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"55.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"54.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"56.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.3","Single Cell Type RNA - Bipolar cells [nTPM]":"24.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"85.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"97.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"94.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"75.8","Single Cell Type RNA - Club cells [nTPM]":"44.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"93.4","Single Cell Type RNA - dendritic cells [nTPM]":"55.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"114.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"137.0","Single Cell Type RNA - Ductal cells [nTPM]":"90.4","Single Cell Type RNA - Early spermatids [nTPM]":"48.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"54.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.2","Single Cell Type RNA - Endothelial cells [nTPM]":"36.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"53.8","Single Cell Type RNA - Erythroid cells [nTPM]":"32.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"101.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"87.5","Single Cell Type RNA - Fibroblasts [nTPM]":"38.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.9","Single Cell Type RNA - granulocytes [nTPM]":"22.9","Single Cell Type RNA - Granulosa cells [nTPM]":"44.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"50.3","Single Cell Type RNA - Hepatocytes [nTPM]":"158.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"101.1","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"74.3","Single Cell Type RNA - Ionocytes [nTPM]":"99.7","Single Cell Type RNA - Kupffer cells [nTPM]":"93.2","Single Cell Type RNA - Langerhans cells [nTPM]":"83.6","Single Cell Type RNA - Late spermatids [nTPM]":"127.1","Single Cell Type RNA - Leydig cells [nTPM]":"52.2","Single Cell Type RNA - Macrophages [nTPM]":"60.3","Single Cell Type RNA - Melanocytes [nTPM]":"69.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"96.9","Single Cell Type RNA - Muller glia cells [nTPM]":"95.2","Single Cell Type RNA - NK-cells [nTPM]":"62.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"71.9","Single Cell Type RNA - Paneth cells [nTPM]":"102.1","Single Cell Type RNA - Peritubular cells [nTPM]":"48.2","Single Cell Type RNA - Plasma cells [nTPM]":"74.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"56.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"215.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"174.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"45.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.3","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.6","Single Cell Type RNA - Spermatocytes [nTPM]":"66.2","Single Cell Type RNA - Spermatogonia [nTPM]":"94.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"50.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"49.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"80.6","Single Cell Type RNA - T-cells [nTPM]":"51.5","Single Cell Type RNA - Theca cells [nTPM]":"52.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"79.6","Single Cell Type RNA - Urothelial cells [nTPM]":"63.4"},{"Gene":"SYN1","Gene synonym":["MRX50"],"Ensembl":"ENSG00000008056","Gene description":"Synapsin I","Uniprot":["P17600"],"Chromosome":"X","Position":"47571901-47619857","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"271.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"27.1","Excitatory neurons":"37.3","Horizontal cells":"28.6","Inhibitory neurons":"34.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"11.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"amygdala":"81.4","basal ganglia":"127.5","cerebral cortex":"271.3","hippocampal formation":"118.3","white matter":"150.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"9.0","HHSteC":"8.1","NTERA-2":"17.4","SCLC-21H":"30.2","SH-SY5Y":"7.9","SuSa":"7.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000397","CAB021929"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"48000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB021929":null,"HPA000397":"AB_1080146"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.9","Tissue RNA - adrenal gland [nTPM]":"11.0","Tissue RNA - amygdala [nTPM]":"81.4","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"127.5","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"9.0","Tissue RNA - cerebral cortex [nTPM]":"271.3","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"15.3","Tissue RNA - hippocampal formation [nTPM]":"118.3","Tissue RNA - hypothalamus [nTPM]":"30.7","Tissue RNA - kidney [nTPM]":"2.2","Tissue RNA - liver [nTPM]":"3.0","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"28.5","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"35.7","Tissue RNA - placenta [nTPM]":"4.4","Tissue RNA - pons [nTPM]":"12.7","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"44.0","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"9.9","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"150.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"5.0","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"9.0","Cell RNA - HAP1 [nTPM]":"0.5","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"2.1","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.5","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"17.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"30.2","Cell RNA - SH-SY5Y [nTPM]":"7.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"7.2","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"81.4","Brain RNA - basal ganglia [nTPM]":"127.5","Brain RNA - cerebellum [nTPM]":"9.0","Brain RNA - cerebral cortex [nTPM]":"271.3","Brain RNA - hippocampal formation [nTPM]":"118.3","Brain RNA - hypothalamus [nTPM]":"30.7","Brain RNA - medulla oblongata [nTPM]":"28.5","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"12.7","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"9.9","Brain RNA - white matter [nTPM]":"150.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"27.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"1.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"6.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"3.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"SYNE1","Gene synonym":["8B","ARCA1","C6orf98","CPG2","dJ45H2.2","enaptin","KIAA0796","MYNE1","Nesp1","Nesprin-1","SCAR8","SYNE-1B"],"Ensembl":"ENSG00000131018","Gene description":"Spectrin repeat containing nuclear envelope protein 1","Uniprot":["Q8NF91"],"Chromosome":"6","Position":"152121684-152637801","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Actin-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Emery-Dreifuss muscular dystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"152.5","choroid plexus":"182.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"550.1","Bipolar cells":"332.1","Excitatory neurons":"494.6","Inhibitory neurons":"482.6","Microglial cells":"315.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"56.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"56.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2 OS":"29.8","U-266\/70":"29.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019113"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"72000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA019113":"AB_1857707"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.4","Tissue RNA - adrenal gland [nTPM]":"17.8","Tissue RNA - amygdala [nTPM]":"60.2","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"68.8","Tissue RNA - bone marrow [nTPM]":"53.6","Tissue RNA - breast [nTPM]":"14.4","Tissue RNA - cerebellum [nTPM]":"152.5","Tissue RNA - cerebral cortex [nTPM]":"70.2","Tissue RNA - cervix [nTPM]":"18.9","Tissue RNA - choroid plexus [nTPM]":"182.9","Tissue RNA - colon [nTPM]":"17.2","Tissue RNA - duodenum [nTPM]":"2.3","Tissue RNA - endometrium 1 [nTPM]":"19.1","Tissue RNA - epididymis [nTPM]":"23.7","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"26.4","Tissue RNA - gallbladder [nTPM]":"7.9","Tissue RNA - heart muscle [nTPM]":"32.3","Tissue RNA - hippocampal formation [nTPM]":"92.4","Tissue RNA - hypothalamus [nTPM]":"58.1","Tissue RNA - kidney [nTPM]":"34.7","Tissue RNA - liver [nTPM]":"14.6","Tissue RNA - lung [nTPM]":"31.3","Tissue RNA - lymph node [nTPM]":"17.1","Tissue RNA - medulla oblongata [nTPM]":"55.0","Tissue RNA - midbrain [nTPM]":"58.8","Tissue RNA - ovary [nTPM]":"44.5","Tissue RNA - pancreas [nTPM]":"20.6","Tissue RNA - parathyroid gland [nTPM]":"23.6","Tissue RNA - pituitary gland [nTPM]":"56.8","Tissue RNA - placenta [nTPM]":"4.4","Tissue RNA - pons [nTPM]":"55.6","Tissue RNA - prostate [nTPM]":"17.0","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"66.3","Tissue RNA - salivary gland [nTPM]":"5.0","Tissue RNA - seminal vesicle [nTPM]":"12.6","Tissue RNA - skeletal muscle [nTPM]":"28.0","Tissue RNA - skin 1 [nTPM]":"19.6","Tissue RNA - small intestine [nTPM]":"11.4","Tissue RNA - smooth muscle [nTPM]":"13.1","Tissue RNA - spinal cord [nTPM]":"38.3","Tissue RNA - spleen [nTPM]":"32.9","Tissue RNA - stomach 1 [nTPM]":"21.6","Tissue RNA - testis [nTPM]":"17.6","Tissue RNA - thalamus [nTPM]":"55.4","Tissue RNA - thymus [nTPM]":"23.9","Tissue RNA - thyroid gland [nTPM]":"44.7","Tissue RNA - tongue [nTPM]":"16.5","Tissue RNA - tonsil [nTPM]":"13.4","Tissue RNA - urinary bladder [nTPM]":"16.3","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"51.5","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"5.8","Cell RNA - AF22 [nTPM]":"3.7","Cell RNA - AN3-CA [nTPM]":"4.4","Cell RNA - ASC diff [nTPM]":"5.7","Cell RNA - ASC TERT1 [nTPM]":"12.1","Cell RNA - BEWO [nTPM]":"1.5","Cell RNA - BJ [nTPM]":"14.7","Cell RNA - BJ hTERT+ [nTPM]":"6.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.0","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"13.5","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"7.5","Cell RNA - GAMG [nTPM]":"11.2","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"1.6","Cell RNA - HBEC3-KT [nTPM]":"3.8","Cell RNA - HBF TERT88 [nTPM]":"3.5","Cell RNA - HDLM-2 [nTPM]":"11.6","Cell RNA - HEK 293 [nTPM]":"4.0","Cell RNA - HEL [nTPM]":"5.2","Cell RNA - HeLa [nTPM]":"4.1","Cell RNA - Hep G2 [nTPM]":"4.0","Cell RNA - HHSteC [nTPM]":"12.8","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"2.7","Cell RNA - HSkMC [nTPM]":"7.9","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.5","Cell RNA - hTERT-HME1 [nTPM]":"14.9","Cell RNA - hTERT-RPE1 [nTPM]":"9.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.8","Cell RNA - JURKAT [nTPM]":"6.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"9.2","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"2.4","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"1.3","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"2.9","Cell RNA - RH-30 [nTPM]":"8.1","Cell RNA - RPMI-8226 [nTPM]":"3.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.7","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"3.9","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"9.8","Cell RNA - SuSa [nTPM]":"3.7","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"9.0","Cell RNA - U-138 MG [nTPM]":"16.3","Cell RNA - U-2 OS [nTPM]":"29.8","Cell RNA - U-2197 [nTPM]":"5.9","Cell RNA - U-251 MG [nTPM]":"7.6","Cell RNA - U-266\/70 [nTPM]":"29.1","Cell RNA - U-266\/84 [nTPM]":"12.5","Cell RNA - U-698 [nTPM]":"23.3","Cell RNA - U-87 MG [nTPM]":"8.8","Cell RNA - U-937 [nTPM]":"2.9","Cell RNA - WM-115 [nTPM]":"4.6","Blood RNA - basophil [nTPM]":"10.2","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"56.8","Blood RNA - gdT-cell [nTPM]":"11.8","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"6.9","Blood RNA - memory CD4 T-cell [nTPM]":"10.3","Blood RNA - memory CD8 T-cell [nTPM]":"13.4","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"8.2","Blood RNA - naive CD4 T-cell [nTPM]":"9.7","Blood RNA - naive CD8 T-cell [nTPM]":"10.9","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"9.9","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"13.2","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"60.2","Brain RNA - basal ganglia [nTPM]":"68.8","Brain RNA - cerebellum [nTPM]":"152.5","Brain RNA - cerebral cortex [nTPM]":"70.2","Brain RNA - hippocampal formation [nTPM]":"92.4","Brain RNA - hypothalamus [nTPM]":"58.1","Brain RNA - medulla oblongata [nTPM]":"55.0","Brain RNA - midbrain [nTPM]":"58.8","Brain RNA - pons [nTPM]":"55.6","Brain RNA - spinal cord [nTPM]":"38.3","Brain RNA - thalamus [nTPM]":"55.4","Brain RNA - white matter [nTPM]":"51.5","Single Cell Type RNA - Adipocytes [nTPM]":"139.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"166.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"215.2","Single Cell Type RNA - Astrocytes [nTPM]":"550.1","Single Cell Type RNA - B-cells [nTPM]":"29.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"332.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"117.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"53.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"200.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"132.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"132.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"118.2","Single Cell Type RNA - Endothelial cells [nTPM]":"127.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"494.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.2","Single Cell Type RNA - Fibroblasts [nTPM]":"79.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"13.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"90.0","Single Cell Type RNA - Hepatocytes [nTPM]":"21.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.0","Single Cell Type RNA - Horizontal cells [nTPM]":"138.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"482.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"15.0","Single Cell Type RNA - Late spermatids [nTPM]":"12.6","Single Cell Type RNA - Leydig cells [nTPM]":"33.2","Single Cell Type RNA - Macrophages [nTPM]":"16.0","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"315.7","Single Cell Type RNA - monocytes [nTPM]":"12.8","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"210.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"256.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"108.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"39.9","Single Cell Type RNA - Plasma cells [nTPM]":"79.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"146.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"145.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"145.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"85.6","Single Cell Type RNA - Spermatocytes [nTPM]":"3.9","Single Cell Type RNA - Spermatogonia [nTPM]":"5.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"74.7","Single Cell Type RNA - Theca cells [nTPM]":"62.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"SYNE4","Gene synonym":["C19orf46","DFNB76","FLJ36445","Nesp4","Nesprin-4"],"Ensembl":"ENSG00000181392","Gene description":"Spectrin repeat containing nuclear envelope family member 4","Uniprot":["Q8N205"],"Chromosome":"19","Position":"36003307-36008813","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"32.0","Breast myoepithelial cells":"35.9","Cytotrophoblasts":"32.6","Syncytiotrophoblasts":"33.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"CACO-2":"32.5","Hep G2":"29.1","MCF7":"34.2","SK-BR-3":"40.1","T-47d":"31.0"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"15","RNA mouse brain regional specific nTPM":{"cerebellum":"6.8"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060253"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060253":"AB_2684233"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.64e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"6.7","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"2.6","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"7.7","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"3.9","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"8.4","Tissue RNA - liver [nTPM]":"12.0","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"5.4","Tissue RNA - parathyroid gland [nTPM]":"12.1","Tissue RNA - pituitary gland [nTPM]":"12.7","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"10.9","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"9.2","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"1.7","Tissue RNA - thyroid gland [nTPM]":"8.6","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"4.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"32.5","Cell RNA - CAPAN-2 [nTPM]":"3.8","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"29.1","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"34.2","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.2","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"5.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"40.1","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"31.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"6.7","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"35.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"20.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"21.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"29.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"12.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.6","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"16.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.9","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.8","Single Cell Type RNA - Urothelial cells [nTPM]":"9.2"},{"Gene":"SYNJ1","Gene synonym":["INPP5G","PARK20"],"Ensembl":"ENSG00000159082","Gene description":"Synaptojanin 1","Uniprot":["O43426"],"Chromosome":"21","Position":"32628759-32728040","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Endocytosis"],"Molecular function":["Hydrolase","RNA-binding"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"45.9","retina":"48.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"110.9","Inhibitory neurons":"91.5","Oligodendrocytes":"61.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011916"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA011916":"AB_1857692"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.43e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.58e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.6","Tissue RNA - adrenal gland [nTPM]":"6.9","Tissue RNA - amygdala [nTPM]":"15.0","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"22.8","Tissue RNA - bone marrow [nTPM]":"23.8","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"45.9","Tissue RNA - cervix [nTPM]":"6.2","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"5.6","Tissue RNA - duodenum [nTPM]":"4.0","Tissue RNA - endometrium 1 [nTPM]":"5.1","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"4.6","Tissue RNA - fallopian tube [nTPM]":"5.0","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"6.4","Tissue RNA - hippocampal formation [nTPM]":"22.1","Tissue RNA - hypothalamus [nTPM]":"9.8","Tissue RNA - kidney [nTPM]":"7.4","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"19.5","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"8.4","Tissue RNA - pituitary gland [nTPM]":"13.8","Tissue RNA - placenta [nTPM]":"9.8","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"4.5","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"48.4","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"3.7","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"4.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"10.2","Tissue RNA - thalamus [nTPM]":"8.7","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"6.4","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"25.9","Cell RNA - A-431 [nTPM]":"5.5","Cell RNA - A549 [nTPM]":"2.9","Cell RNA - AF22 [nTPM]":"5.0","Cell RNA - AN3-CA [nTPM]":"5.7","Cell RNA - ASC diff [nTPM]":"8.9","Cell RNA - ASC TERT1 [nTPM]":"7.1","Cell RNA - BEWO [nTPM]":"10.3","Cell RNA - BJ [nTPM]":"11.3","Cell RNA - BJ hTERT+ [nTPM]":"6.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"6.1","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"6.9","Cell RNA - GAMG [nTPM]":"8.9","Cell RNA - HaCaT [nTPM]":"5.0","Cell RNA - HAP1 [nTPM]":"8.9","Cell RNA - HBEC3-KT [nTPM]":"6.8","Cell RNA - HBF TERT88 [nTPM]":"8.4","Cell RNA - HDLM-2 [nTPM]":"6.8","Cell RNA - HEK 293 [nTPM]":"8.1","Cell RNA - HEL [nTPM]":"13.8","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"5.6","Cell RNA - HMC-1 [nTPM]":"11.7","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.0","Cell RNA - hTERT-HME1 [nTPM]":"6.1","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"10.8","Cell RNA - JURKAT [nTPM]":"7.3","Cell RNA - K-562 [nTPM]":"10.6","Cell RNA - Karpas-707 [nTPM]":"11.6","Cell RNA - LHCN-M2 [nTPM]":"9.0","Cell RNA - MCF7 [nTPM]":"5.5","Cell RNA - MOLT-4 [nTPM]":"5.5","Cell RNA - NB-4 [nTPM]":"5.1","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"6.4","Cell RNA - PC-3 [nTPM]":"6.0","Cell RNA - REH [nTPM]":"6.1","Cell RNA - RH-30 [nTPM]":"11.1","Cell RNA - RPMI-8226 [nTPM]":"7.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.5","Cell RNA - RT4 [nTPM]":"4.3","Cell RNA - SCLC-21H [nTPM]":"5.6","Cell RNA - SH-SY5Y [nTPM]":"4.5","Cell RNA - SiHa [nTPM]":"14.0","Cell RNA - SK-BR-3 [nTPM]":"8.4","Cell RNA - SK-MEL-30 [nTPM]":"5.6","Cell RNA - SuSa [nTPM]":"6.9","Cell RNA - T-47d [nTPM]":"7.8","Cell RNA - THP-1 [nTPM]":"7.2","Cell RNA - TIME [nTPM]":"11.2","Cell RNA - U-138 MG [nTPM]":"10.0","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"8.2","Cell RNA - U-251 MG [nTPM]":"6.4","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"7.8","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"8.0","Cell RNA - U-937 [nTPM]":"10.7","Cell RNA - WM-115 [nTPM]":"8.7","Blood RNA - basophil [nTPM]":"3.4","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"6.9","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"5.2","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"9.1","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"15.0","Brain RNA - basal ganglia [nTPM]":"22.8","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"45.9","Brain RNA - hippocampal formation [nTPM]":"22.1","Brain RNA - hypothalamus [nTPM]":"9.8","Brain RNA - medulla oblongata [nTPM]":"19.5","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"8.7","Brain RNA - white matter [nTPM]":"25.9","Single Cell Type RNA - Adipocytes [nTPM]":"10.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.4","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"24.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"4.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.7","Single Cell Type RNA - dendritic cells [nTPM]":"7.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"19.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.7","Single Cell Type RNA - Endothelial cells [nTPM]":"11.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"110.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.8","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"2.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"4.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"91.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"11.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"15.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"6.5","Single Cell Type RNA - Muller glia cells [nTPM]":"21.8","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"61.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.8","Single Cell Type RNA - Paneth cells [nTPM]":"5.3","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"45.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.8","Single Cell Type RNA - Spermatocytes [nTPM]":"22.1","Single Cell Type RNA - Spermatogonia [nTPM]":"13.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - T-cells [nTPM]":"9.9","Single Cell Type RNA - Theca cells [nTPM]":"2.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.4","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"SYT14","Gene synonym":["FLJ34198","sytXIV"],"Ensembl":"ENSG00000143469","Gene description":"Synaptotagmin 14","Uniprot":["Q8NB59"],"Chromosome":"1","Position":"209900923-210171389","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"7.0","retina":"1.9","testis":"3.2","thyroid gland":"5.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"208.7","Inhibitory neurons":"213.9","Oligodendrocyte precursor cells":"152.8","Oligodendrocytes":"197.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"1.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"7.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"9.7","GAMG":"6.7","hTERT-HME1":"4.7","SCLC-21H":"6.5","U-138 MG":"6.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036963"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036963":"AB_10670378"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-5"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"7.0","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"5.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"2.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"6.7","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.4","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"4.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"6.5","Cell RNA - SH-SY5Y [nTPM]":"2.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.6","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"6.4","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"7.0","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"30.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"30.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"17.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"208.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"213.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"152.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"197.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"6.0","Single Cell Type RNA - Spermatogonia [nTPM]":"16.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"SYT2","Gene synonym":[],"Ensembl":"ENSG00000143858","Gene description":"Synaptotagmin 2","Uniprot":["Q8N9I0"],"Chromosome":"1","Position":"202590596-202710454","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"73.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"23.2","Inhibitory neurons":"22.7","Oligodendrocytes":"7.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"testis cancer":"3.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"AF22":"8.5","NTERA-2":"5.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063655"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063655":"AB_2685077"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"8.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"46.3","Tissue RNA - cerebral cortex [nTPM]":"73.4","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"16.8","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"66.0","Tissue RNA - midbrain [nTPM]":"17.5","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"68.3","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"13.9","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"23.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"20.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"8.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"5.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"8.8","Brain RNA - cerebellum [nTPM]":"46.3","Brain RNA - cerebral cortex [nTPM]":"73.4","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"16.8","Brain RNA - medulla oblongata [nTPM]":"66.0","Brain RNA - midbrain [nTPM]":"17.5","Brain RNA - pons [nTPM]":"68.3","Brain RNA - spinal cord [nTPM]":"13.9","Brain RNA - thalamus [nTPM]":"23.1","Brain RNA - white matter [nTPM]":"20.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"SZT2","Gene synonym":["C1orf84","FLJ10387","FLJ34502","KIAA0467","RP11-506B15.1","SZT2A","SZT2B"],"Ensembl":"ENSG00000198198","Gene description":"SZT2 subunit of KICSTOR complex","Uniprot":["Q5T011"],"Chromosome":"1","Position":"43389882-43454247","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"62.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029012"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Vesicles","Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA029012":"AB_10600817"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.47e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.20e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"5.3","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"6.1","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"7.2","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"7.0","Tissue RNA - gallbladder [nTPM]":"2.7","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"4.4","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"4.2","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"8.8","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"2.5","Tissue RNA - prostate [nTPM]":"6.5","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"4.0","Tissue RNA - salivary gland [nTPM]":"6.5","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"6.6","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"3.6","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"7.1","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"9.0","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"6.2","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"4.5","Cell RNA - A549 [nTPM]":"4.4","Cell RNA - AF22 [nTPM]":"3.7","Cell RNA - AN3-CA [nTPM]":"3.4","Cell RNA - ASC diff [nTPM]":"9.1","Cell RNA - ASC TERT1 [nTPM]":"4.5","Cell RNA - BEWO [nTPM]":"5.7","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"4.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"5.0","Cell RNA - Daudi [nTPM]":"4.1","Cell RNA - EFO-21 [nTPM]":"4.1","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"3.2","Cell RNA - HaCaT [nTPM]":"5.1","Cell RNA - HAP1 [nTPM]":"3.7","Cell RNA - HBEC3-KT [nTPM]":"6.3","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"5.1","Cell RNA - HEK 293 [nTPM]":"3.4","Cell RNA - HEL [nTPM]":"7.5","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"2.7","Cell RNA - HHSteC [nTPM]":"3.4","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"6.2","Cell RNA - HSkMC [nTPM]":"4.8","Cell RNA - hTCEpi [nTPM]":"4.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.7","Cell RNA - hTERT-HME1 [nTPM]":"7.5","Cell RNA - hTERT-RPE1 [nTPM]":"5.0","Cell RNA - HUVEC TERT2 [nTPM]":"5.2","Cell RNA - JURKAT [nTPM]":"4.7","Cell RNA - K-562 [nTPM]":"3.4","Cell RNA - Karpas-707 [nTPM]":"6.8","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"2.1","Cell RNA - MOLT-4 [nTPM]":"4.1","Cell RNA - NB-4 [nTPM]":"1.6","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"4.5","Cell RNA - REH [nTPM]":"4.5","Cell RNA - RH-30 [nTPM]":"5.1","Cell RNA - RPMI-8226 [nTPM]":"4.9","Cell RNA - RPTEC TERT1 [nTPM]":"2.6","Cell RNA - RT4 [nTPM]":"6.2","Cell RNA - SCLC-21H [nTPM]":"3.8","Cell RNA - SH-SY5Y [nTPM]":"3.4","Cell RNA - SiHa [nTPM]":"7.8","Cell RNA - SK-BR-3 [nTPM]":"5.9","Cell RNA - SK-MEL-30 [nTPM]":"4.0","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"3.2","Cell RNA - THP-1 [nTPM]":"8.8","Cell RNA - TIME [nTPM]":"6.5","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"6.4","Cell RNA - U-251 MG [nTPM]":"6.5","Cell RNA - U-266\/70 [nTPM]":"7.3","Cell RNA - U-266\/84 [nTPM]":"2.8","Cell RNA - U-698 [nTPM]":"3.4","Cell RNA - U-87 MG [nTPM]":"4.9","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"3.1","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"2.5","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"8.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.3","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"10.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"16.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"9.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"14.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.2","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.9","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"19.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"13.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"15.8","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"9.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"11.6","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.8","Single Cell Type RNA - Paneth cells [nTPM]":"3.7","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.2","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.1","Single Cell Type RNA - Spermatogonia [nTPM]":"8.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"12.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"TACSTD2","Gene synonym":["EGP-1","GA733-1","M1S1","TROP2"],"Ensembl":"ENSG00000184292","Gene description":"Tumor associated calcium signal transducer 2","Uniprot":["P09758"],"Chromosome":"1","Position":"58575433-58577252","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Tumor antigen"],"Disease involvement":["Amyloidosis","Corneal dystrophy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"989.6","salivary gland":"468.5","skin 1":"438.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"6559.0","Basal respiratory cells":"3141.0","Club cells":"2499.0","Prostatic glandular cells":"3724.1","Squamous epithelial cells":"2716.6","Urothelial cells":"8102.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"15.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"79","RNA blood lineage specific nTPM":{"dendritic cells":"4.3","granulocytes":"15.0","monocytes":"4.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"766.6","CAPAN-2":"1005.9","HaCaT":"1010.0","RT4":"355.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043104","HPA055067","CAB072852"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli","Vesicles"],"Antibody RRID":{"CAB072852":null,"HPA043104":"AB_10960710","HPA055067":"AB_2682687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"13.5","Tissue RNA - breast [nTPM]":"135.8","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"218.6","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"19.1","Tissue RNA - epididymis [nTPM]":"25.3","Tissue RNA - esophagus [nTPM]":"989.6","Tissue RNA - fallopian tube [nTPM]":"27.7","Tissue RNA - gallbladder [nTPM]":"13.0","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"137.9","Tissue RNA - liver [nTPM]":"4.0","Tissue RNA - lung [nTPM]":"71.2","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"81.1","Tissue RNA - parathyroid gland [nTPM]":"3.5","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"17.7","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"126.8","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"468.5","Tissue RNA - seminal vesicle [nTPM]":"97.1","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"438.8","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"65.7","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"9.2","Tissue RNA - thyroid gland [nTPM]":"5.0","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"180.0","Tissue RNA - urinary bladder [nTPM]":"234.6","Tissue RNA - vagina [nTPM]":"375.0","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"766.6","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"280.1","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"1005.9","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"94.7","Cell RNA - fHDF\/TERT166 [nTPM]":"64.2","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"1010.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"186.5","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"19.7","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"274.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"11.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"42.5","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"166.3","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"167.0","Cell RNA - PC-3 [nTPM]":"1.4","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"137.0","Cell RNA - RT4 [nTPM]":"355.3","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"32.4","Cell RNA - SK-BR-3 [nTPM]":"264.9","Cell RNA - SK-MEL-30 [nTPM]":"1.0","Cell RNA - SuSa [nTPM]":"3.2","Cell RNA - T-47d [nTPM]":"173.6","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"45.4","Cell RNA - U-138 MG [nTPM]":"1.0","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"1.7","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"1.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"4.2","Blood RNA - eosinophil [nTPM]":"15.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.3","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"9.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"346.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"109.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1490.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6559.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3141.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1226.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"789.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"445.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"338.8","Single Cell Type RNA - Club cells [nTPM]":"2499.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1278.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"107.1","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"2165.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"482.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"48.6","Single Cell Type RNA - Endothelial cells [nTPM]":"60.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1263.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.1","Single Cell Type RNA - Fibroblasts [nTPM]":"36.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"143.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"608.7","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"1143.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"203.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"34.8","Single Cell Type RNA - Melanocytes [nTPM]":"113.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"31.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1778.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3724.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1080.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"142.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2716.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1531.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"78.4","Single Cell Type RNA - T-cells [nTPM]":"32.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"8102.8"},{"Gene":"TAF1","Gene synonym":["BA2R","CCG1","CCGS","DYT3","DYT3\/TAF1","KAT4","NSCL2","TAF2A","TAFII250"],"Ensembl":"ENSG00000147133","Gene description":"TATA-box binding protein associated factor 1","Uniprot":["P21675"],"Chromosome":"X","Position":"71366264-71532374","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Acyltransferase","DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dystonia","Mental retardation","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"81.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001075","CAB016283"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB016283":"AB_671202","HPA001075":"AB_1080179"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.54e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"10.3","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"12.7","Tissue RNA - bone marrow [nTPM]":"12.8","Tissue RNA - breast [nTPM]":"12.3","Tissue RNA - cerebellum [nTPM]":"13.7","Tissue RNA - cerebral cortex [nTPM]":"11.1","Tissue RNA - cervix [nTPM]":"11.1","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"6.6","Tissue RNA - endometrium 1 [nTPM]":"13.8","Tissue RNA - epididymis [nTPM]":"12.9","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"11.1","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"9.3","Tissue RNA - hypothalamus [nTPM]":"14.1","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"9.1","Tissue RNA - lymph node [nTPM]":"14.1","Tissue RNA - medulla oblongata [nTPM]":"11.5","Tissue RNA - midbrain [nTPM]":"11.3","Tissue RNA - ovary [nTPM]":"14.4","Tissue RNA - pancreas [nTPM]":"9.8","Tissue RNA - parathyroid gland [nTPM]":"12.2","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"10.9","Tissue RNA - prostate [nTPM]":"10.0","Tissue RNA - rectum [nTPM]":"10.0","Tissue RNA - retina [nTPM]":"27.3","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"10.1","Tissue RNA - skeletal muscle [nTPM]":"10.5","Tissue RNA - skin 1 [nTPM]":"13.3","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"10.9","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"15.4","Tissue RNA - stomach 1 [nTPM]":"10.6","Tissue RNA - testis [nTPM]":"7.2","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"14.8","Tissue RNA - thyroid gland [nTPM]":"12.7","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"12.4","Tissue RNA - urinary bladder [nTPM]":"9.2","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"16.8","Cell RNA - A-431 [nTPM]":"18.6","Cell RNA - A549 [nTPM]":"15.9","Cell RNA - AF22 [nTPM]":"18.2","Cell RNA - AN3-CA [nTPM]":"12.4","Cell RNA - ASC diff [nTPM]":"14.6","Cell RNA - ASC TERT1 [nTPM]":"23.2","Cell RNA - BEWO [nTPM]":"11.0","Cell RNA - BJ [nTPM]":"13.3","Cell RNA - BJ hTERT+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.1","Cell RNA - CACO-2 [nTPM]":"12.3","Cell RNA - CAPAN-2 [nTPM]":"11.3","Cell RNA - Daudi [nTPM]":"17.6","Cell RNA - EFO-21 [nTPM]":"11.5","Cell RNA - fHDF\/TERT166 [nTPM]":"14.9","Cell RNA - GAMG [nTPM]":"12.3","Cell RNA - HaCaT [nTPM]":"17.5","Cell RNA - HAP1 [nTPM]":"24.1","Cell RNA - HBEC3-KT [nTPM]":"11.0","Cell RNA - HBF TERT88 [nTPM]":"17.0","Cell RNA - HDLM-2 [nTPM]":"11.2","Cell RNA - HEK 293 [nTPM]":"21.9","Cell RNA - HEL [nTPM]":"20.1","Cell RNA - HeLa [nTPM]":"22.1","Cell RNA - Hep G2 [nTPM]":"13.1","Cell RNA - HHSteC [nTPM]":"11.1","Cell RNA - HL-60 [nTPM]":"39.7","Cell RNA - HMC-1 [nTPM]":"19.4","Cell RNA - HSkMC [nTPM]":"14.1","Cell RNA - hTCEpi [nTPM]":"11.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.2","Cell RNA - hTERT-HME1 [nTPM]":"27.2","Cell RNA - hTERT-RPE1 [nTPM]":"12.8","Cell RNA - HUVEC TERT2 [nTPM]":"14.7","Cell RNA - JURKAT [nTPM]":"13.2","Cell RNA - K-562 [nTPM]":"28.2","Cell RNA - Karpas-707 [nTPM]":"41.1","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"14.5","Cell RNA - MOLT-4 [nTPM]":"22.4","Cell RNA - NB-4 [nTPM]":"25.4","Cell RNA - NTERA-2 [nTPM]":"20.9","Cell RNA - OE19 [nTPM]":"23.5","Cell RNA - PC-3 [nTPM]":"20.8","Cell RNA - REH [nTPM]":"19.8","Cell RNA - RH-30 [nTPM]":"35.8","Cell RNA - RPMI-8226 [nTPM]":"21.6","Cell RNA - RPTEC TERT1 [nTPM]":"11.1","Cell RNA - RT4 [nTPM]":"25.0","Cell RNA - SCLC-21H [nTPM]":"9.0","Cell RNA - SH-SY5Y [nTPM]":"14.5","Cell RNA - SiHa [nTPM]":"37.7","Cell RNA - SK-BR-3 [nTPM]":"13.6","Cell RNA - SK-MEL-30 [nTPM]":"18.7","Cell RNA - SuSa [nTPM]":"14.3","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"22.9","Cell RNA - TIME [nTPM]":"18.6","Cell RNA - U-138 MG [nTPM]":"16.5","Cell RNA - U-2 OS [nTPM]":"14.2","Cell RNA - U-2197 [nTPM]":"13.4","Cell RNA - U-251 MG [nTPM]":"9.7","Cell RNA - U-266\/70 [nTPM]":"17.5","Cell RNA - U-266\/84 [nTPM]":"17.4","Cell RNA - U-698 [nTPM]":"21.4","Cell RNA - U-87 MG [nTPM]":"9.0","Cell RNA - U-937 [nTPM]":"33.2","Cell RNA - WM-115 [nTPM]":"12.5","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"10.3","Brain RNA - basal ganglia [nTPM]":"12.7","Brain RNA - cerebellum [nTPM]":"13.7","Brain RNA - cerebral cortex [nTPM]":"11.1","Brain RNA - hippocampal formation [nTPM]":"9.3","Brain RNA - hypothalamus [nTPM]":"14.1","Brain RNA - medulla oblongata [nTPM]":"11.5","Brain RNA - midbrain [nTPM]":"11.3","Brain RNA - pons [nTPM]":"10.9","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"16.8","Single Cell Type RNA - Adipocytes [nTPM]":"26.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.7","Single Cell Type RNA - Astrocytes [nTPM]":"44.7","Single Cell Type RNA - B-cells [nTPM]":"21.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"37.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"23.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"81.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.6","Single Cell Type RNA - dendritic cells [nTPM]":"21.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.4","Single Cell Type RNA - Endothelial cells [nTPM]":"24.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"28.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"54.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.9","Single Cell Type RNA - Fibroblasts [nTPM]":"17.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.9","Single Cell Type RNA - granulocytes [nTPM]":"23.4","Single Cell Type RNA - Granulosa cells [nTPM]":"23.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"12.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"52.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"16.2","Single Cell Type RNA - Langerhans cells [nTPM]":"20.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"22.1","Single Cell Type RNA - Macrophages [nTPM]":"20.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"47.8","Single Cell Type RNA - monocytes [nTPM]":"23.9","Single Cell Type RNA - Muller glia cells [nTPM]":"17.0","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"79.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.3","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"67.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.0","Single Cell Type RNA - Spermatocytes [nTPM]":"9.3","Single Cell Type RNA - Spermatogonia [nTPM]":"10.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - T-cells [nTPM]":"23.8","Single Cell Type RNA - Theca cells [nTPM]":"25.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.6","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"TARDBP","Gene synonym":["ALS10","TDP-43"],"Ensembl":"ENSG00000120948","Gene description":"TAR DNA binding protein","Uniprot":["Q13148"],"Chromosome":"1","Position":"11012344-11030528","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Biological rhythms","mRNA processing","mRNA splicing","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Repressor","RNA-binding"],"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003703","HPA017284"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB003703":"AB_425904","HPA017284":"AB_1857775"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.15e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"83.4","Tissue RNA - adrenal gland [nTPM]":"80.1","Tissue RNA - amygdala [nTPM]":"71.9","Tissue RNA - appendix [nTPM]":"87.1","Tissue RNA - basal ganglia [nTPM]":"80.6","Tissue RNA - bone marrow [nTPM]":"69.7","Tissue RNA - breast [nTPM]":"83.3","Tissue RNA - cerebellum [nTPM]":"84.7","Tissue RNA - cerebral cortex [nTPM]":"79.0","Tissue RNA - cervix [nTPM]":"93.9","Tissue RNA - choroid plexus [nTPM]":"78.1","Tissue RNA - colon [nTPM]":"94.5","Tissue RNA - duodenum [nTPM]":"77.4","Tissue RNA - endometrium 1 [nTPM]":"90.9","Tissue RNA - epididymis [nTPM]":"78.8","Tissue RNA - esophagus [nTPM]":"111.1","Tissue RNA - fallopian tube [nTPM]":"84.1","Tissue RNA - gallbladder [nTPM]":"58.7","Tissue RNA - heart muscle [nTPM]":"93.0","Tissue RNA - hippocampal formation [nTPM]":"69.4","Tissue RNA - hypothalamus [nTPM]":"78.5","Tissue RNA - kidney [nTPM]":"93.8","Tissue RNA - liver [nTPM]":"105.5","Tissue RNA - lung [nTPM]":"91.6","Tissue RNA - lymph node [nTPM]":"106.5","Tissue RNA - medulla oblongata [nTPM]":"75.5","Tissue RNA - midbrain [nTPM]":"77.2","Tissue RNA - ovary [nTPM]":"103.5","Tissue RNA - pancreas [nTPM]":"77.2","Tissue RNA - parathyroid gland [nTPM]":"86.7","Tissue RNA - pituitary gland [nTPM]":"89.1","Tissue RNA - placenta [nTPM]":"82.7","Tissue RNA - pons [nTPM]":"76.4","Tissue RNA - prostate [nTPM]":"90.1","Tissue RNA - rectum [nTPM]":"94.5","Tissue RNA - retina [nTPM]":"119.9","Tissue RNA - salivary gland [nTPM]":"86.6","Tissue RNA - seminal vesicle [nTPM]":"78.8","Tissue RNA - skeletal muscle [nTPM]":"138.9","Tissue RNA - skin 1 [nTPM]":"96.1","Tissue RNA - small intestine [nTPM]":"94.5","Tissue RNA - smooth muscle [nTPM]":"81.2","Tissue RNA - spinal cord [nTPM]":"74.8","Tissue RNA - spleen [nTPM]":"97.4","Tissue RNA - stomach 1 [nTPM]":"82.4","Tissue RNA - testis [nTPM]":"68.2","Tissue RNA - thalamus [nTPM]":"74.7","Tissue RNA - thymus [nTPM]":"115.1","Tissue RNA - thyroid gland [nTPM]":"96.6","Tissue RNA - tongue [nTPM]":"102.9","Tissue RNA - tonsil [nTPM]":"122.9","Tissue RNA - urinary bladder [nTPM]":"87.6","Tissue RNA - vagina [nTPM]":"95.8","Tissue RNA - white matter [nTPM]":"86.0","Cell RNA - A-431 [nTPM]":"244.7","Cell RNA - A549 [nTPM]":"164.4","Cell RNA - AF22 [nTPM]":"270.4","Cell RNA - AN3-CA [nTPM]":"143.5","Cell RNA - ASC diff [nTPM]":"143.9","Cell RNA - ASC TERT1 [nTPM]":"118.2","Cell RNA - BEWO [nTPM]":"160.3","Cell RNA - BJ [nTPM]":"164.7","Cell RNA - BJ hTERT+ [nTPM]":"142.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"263.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"195.5","Cell RNA - CACO-2 [nTPM]":"187.9","Cell RNA - CAPAN-2 [nTPM]":"175.6","Cell RNA - Daudi [nTPM]":"316.3","Cell RNA - EFO-21 [nTPM]":"118.1","Cell RNA - fHDF\/TERT166 [nTPM]":"180.6","Cell RNA - GAMG [nTPM]":"154.3","Cell RNA - HaCaT [nTPM]":"169.2","Cell RNA - HAP1 [nTPM]":"333.1","Cell RNA - HBEC3-KT [nTPM]":"187.6","Cell RNA - HBF TERT88 [nTPM]":"336.0","Cell RNA - HDLM-2 [nTPM]":"175.1","Cell RNA - HEK 293 [nTPM]":"153.8","Cell RNA - HEL [nTPM]":"241.2","Cell RNA - HeLa [nTPM]":"275.2","Cell RNA - Hep G2 [nTPM]":"257.9","Cell RNA - HHSteC [nTPM]":"119.4","Cell RNA - HL-60 [nTPM]":"290.5","Cell RNA - HMC-1 [nTPM]":"158.9","Cell RNA - HSkMC [nTPM]":"99.5","Cell RNA - hTCEpi [nTPM]":"211.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"184.5","Cell RNA - hTERT-HME1 [nTPM]":"147.9","Cell RNA - hTERT-RPE1 [nTPM]":"143.8","Cell RNA - HUVEC TERT2 [nTPM]":"188.6","Cell RNA - JURKAT [nTPM]":"126.7","Cell RNA - K-562 [nTPM]":"319.0","Cell RNA - Karpas-707 [nTPM]":"176.4","Cell RNA - LHCN-M2 [nTPM]":"221.7","Cell RNA - MCF7 [nTPM]":"195.0","Cell RNA - MOLT-4 [nTPM]":"215.6","Cell RNA - NB-4 [nTPM]":"228.6","Cell RNA - NTERA-2 [nTPM]":"221.0","Cell RNA - OE19 [nTPM]":"232.2","Cell RNA - PC-3 [nTPM]":"141.7","Cell RNA - REH [nTPM]":"256.9","Cell RNA - RH-30 [nTPM]":"214.4","Cell RNA - RPMI-8226 [nTPM]":"206.2","Cell RNA - RPTEC TERT1 [nTPM]":"186.0","Cell RNA - RT4 [nTPM]":"179.1","Cell RNA - SCLC-21H [nTPM]":"187.9","Cell RNA - SH-SY5Y [nTPM]":"150.8","Cell RNA - SiHa [nTPM]":"221.3","Cell RNA - SK-BR-3 [nTPM]":"173.7","Cell RNA - SK-MEL-30 [nTPM]":"128.8","Cell RNA - SuSa [nTPM]":"197.1","Cell RNA - T-47d [nTPM]":"173.8","Cell RNA - THP-1 [nTPM]":"200.9","Cell RNA - TIME [nTPM]":"174.8","Cell RNA - U-138 MG [nTPM]":"173.8","Cell RNA - U-2 OS [nTPM]":"207.8","Cell RNA - U-2197 [nTPM]":"146.3","Cell RNA - U-251 MG [nTPM]":"236.9","Cell RNA - U-266\/70 [nTPM]":"133.3","Cell RNA - U-266\/84 [nTPM]":"176.2","Cell RNA - U-698 [nTPM]":"336.3","Cell RNA - U-87 MG [nTPM]":"116.2","Cell RNA - U-937 [nTPM]":"288.2","Cell RNA - WM-115 [nTPM]":"192.0","Blood RNA - basophil [nTPM]":"38.0","Blood RNA - classical monocyte [nTPM]":"38.0","Blood RNA - eosinophil [nTPM]":"33.7","Blood RNA - gdT-cell [nTPM]":"46.7","Blood RNA - intermediate monocyte [nTPM]":"48.6","Blood RNA - MAIT T-cell [nTPM]":"57.4","Blood RNA - memory B-cell [nTPM]":"55.2","Blood RNA - memory CD4 T-cell [nTPM]":"46.9","Blood RNA - memory CD8 T-cell [nTPM]":"45.4","Blood RNA - myeloid DC [nTPM]":"61.7","Blood RNA - naive B-cell [nTPM]":"39.6","Blood RNA - naive CD4 T-cell [nTPM]":"46.3","Blood RNA - naive CD8 T-cell [nTPM]":"50.5","Blood RNA - neutrophil [nTPM]":"15.4","Blood RNA - NK-cell [nTPM]":"67.2","Blood RNA - non-classical monocyte [nTPM]":"50.0","Blood RNA - plasmacytoid DC [nTPM]":"43.1","Blood RNA - T-reg [nTPM]":"54.3","Blood RNA - total PBMC [nTPM]":"36.4","Brain RNA - amygdala [nTPM]":"71.9","Brain RNA - basal ganglia [nTPM]":"80.6","Brain RNA - cerebellum [nTPM]":"84.7","Brain RNA - cerebral cortex [nTPM]":"79.0","Brain RNA - hippocampal formation [nTPM]":"69.4","Brain RNA - hypothalamus [nTPM]":"78.5","Brain RNA - medulla oblongata [nTPM]":"75.5","Brain RNA - midbrain [nTPM]":"77.2","Brain RNA - pons [nTPM]":"76.4","Brain RNA - spinal cord [nTPM]":"74.8","Brain RNA - thalamus [nTPM]":"74.7","Brain RNA - white matter [nTPM]":"86.0","Single Cell Type RNA - Adipocytes [nTPM]":"35.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"74.4","Single Cell Type RNA - Astrocytes [nTPM]":"29.4","Single Cell Type RNA - B-cells [nTPM]":"57.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"114.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"89.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Bipolar cells [nTPM]":"37.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"52.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"68.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"57.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.2","Single Cell Type RNA - dendritic cells [nTPM]":"46.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"54.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"50.8","Single Cell Type RNA - Early spermatids [nTPM]":"9.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"50.0","Single Cell Type RNA - Endothelial cells [nTPM]":"54.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.3","Single Cell Type RNA - Erythroid cells [nTPM]":"63.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"54.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"84.5","Single Cell Type RNA - Fibroblasts [nTPM]":"45.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.7","Single Cell Type RNA - granulocytes [nTPM]":"42.3","Single Cell Type RNA - Granulosa cells [nTPM]":"45.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.0","Single Cell Type RNA - Hepatocytes [nTPM]":"51.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.1","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"50.1","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"45.9","Single Cell Type RNA - Langerhans cells [nTPM]":"46.3","Single Cell Type RNA - Late spermatids [nTPM]":"12.3","Single Cell Type RNA - Leydig cells [nTPM]":"47.2","Single Cell Type RNA - Macrophages [nTPM]":"37.8","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"54.3","Single Cell Type RNA - Muller glia cells [nTPM]":"36.2","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"57.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"52.9","Single Cell Type RNA - Paneth cells [nTPM]":"36.1","Single Cell Type RNA - Peritubular cells [nTPM]":"51.6","Single Cell Type RNA - Plasma cells [nTPM]":"48.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"71.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"43.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"54.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.9","Single Cell Type RNA - Spermatocytes [nTPM]":"64.9","Single Cell Type RNA - Spermatogonia [nTPM]":"32.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"52.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"114.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"73.5","Single Cell Type RNA - T-cells [nTPM]":"41.3","Single Cell Type RNA - Theca cells [nTPM]":"23.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.6","Single Cell Type RNA - Urothelial cells [nTPM]":"71.3"},{"Gene":"TBC1D24","Gene synonym":["DFNA65","DFNB86","KIAA1171","TLDC6"],"Ensembl":"ENSG00000162065","Gene description":"TBC1 domain family member 24","Uniprot":["Q9ULP9"],"Chromosome":"16","Position":"2475051-2509560","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Deafness","Disease variant","Epilepsy","Mental retardation","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"16.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"43.8","Inhibitory neurons":"34.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"34.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044712","HPA068080"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA044712":"AB_10795619","HPA068080":"AB_2685948"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.22e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.8","Tissue RNA - adrenal gland [nTPM]":"3.3","Tissue RNA - amygdala [nTPM]":"7.5","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"8.1","Tissue RNA - bone marrow [nTPM]":"2.5","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"10.5","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"4.3","Tissue RNA - liver [nTPM]":"3.7","Tissue RNA - lung [nTPM]":"3.9","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"10.6","Tissue RNA - parathyroid gland [nTPM]":"1.9","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"16.5","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"3.4","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"1.8","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"3.4","Cell RNA - A549 [nTPM]":"6.7","Cell RNA - AF22 [nTPM]":"4.5","Cell RNA - AN3-CA [nTPM]":"9.2","Cell RNA - ASC diff [nTPM]":"5.1","Cell RNA - ASC TERT1 [nTPM]":"5.1","Cell RNA - BEWO [nTPM]":"3.8","Cell RNA - BJ [nTPM]":"6.2","Cell RNA - BJ hTERT+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.5","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"2.9","Cell RNA - Daudi [nTPM]":"8.6","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"4.9","Cell RNA - GAMG [nTPM]":"1.9","Cell RNA - HaCaT [nTPM]":"6.3","Cell RNA - HAP1 [nTPM]":"7.1","Cell RNA - HBEC3-KT [nTPM]":"2.0","Cell RNA - HBF TERT88 [nTPM]":"2.9","Cell RNA - HDLM-2 [nTPM]":"9.3","Cell RNA - HEK 293 [nTPM]":"8.0","Cell RNA - HEL [nTPM]":"8.0","Cell RNA - HeLa [nTPM]":"9.5","Cell RNA - Hep G2 [nTPM]":"5.5","Cell RNA - HHSteC [nTPM]":"3.1","Cell RNA - HL-60 [nTPM]":"5.9","Cell RNA - HMC-1 [nTPM]":"3.2","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"2.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.5","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"2.8","Cell RNA - HUVEC TERT2 [nTPM]":"5.1","Cell RNA - JURKAT [nTPM]":"3.3","Cell RNA - K-562 [nTPM]":"9.9","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"3.8","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"4.1","Cell RNA - NB-4 [nTPM]":"11.9","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"3.2","Cell RNA - PC-3 [nTPM]":"4.3","Cell RNA - REH [nTPM]":"20.9","Cell RNA - RH-30 [nTPM]":"8.5","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"2.3","Cell RNA - SCLC-21H [nTPM]":"34.7","Cell RNA - SH-SY5Y [nTPM]":"8.5","Cell RNA - SiHa [nTPM]":"3.8","Cell RNA - SK-BR-3 [nTPM]":"15.3","Cell RNA - SK-MEL-30 [nTPM]":"2.6","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"5.2","Cell RNA - TIME [nTPM]":"5.4","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"7.9","Cell RNA - U-251 MG [nTPM]":"6.2","Cell RNA - U-266\/70 [nTPM]":"3.2","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"11.0","Cell RNA - U-87 MG [nTPM]":"3.4","Cell RNA - U-937 [nTPM]":"8.5","Cell RNA - WM-115 [nTPM]":"7.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"7.5","Brain RNA - basal ganglia [nTPM]":"8.1","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"10.5","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.7","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"19.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"6.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"5.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"5.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"6.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"6.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"3.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"3.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.8","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"8.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"3.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"TBCD","Gene synonym":[],"Ensembl":"ENSG00000141556","Gene description":"Tubulin folding cofactor D","Uniprot":["Q9BTW9"],"Chromosome":"17","Position":"82752065-82945914","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone","GTPase activation"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MOLT-4":"204.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6200","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045200":"AB_10969134"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Tissue RNA - adipose tissue [nTPM]":"34.3","Tissue RNA - adrenal gland [nTPM]":"23.9","Tissue RNA - amygdala [nTPM]":"17.6","Tissue RNA - appendix [nTPM]":"22.2","Tissue RNA - basal ganglia [nTPM]":"19.0","Tissue RNA - bone marrow [nTPM]":"23.2","Tissue RNA - breast [nTPM]":"31.7","Tissue RNA - cerebellum [nTPM]":"12.1","Tissue RNA - cerebral cortex [nTPM]":"17.6","Tissue RNA - cervix [nTPM]":"32.7","Tissue RNA - choroid plexus [nTPM]":"17.9","Tissue RNA - colon [nTPM]":"22.9","Tissue RNA - duodenum [nTPM]":"15.5","Tissue RNA - endometrium 1 [nTPM]":"27.1","Tissue RNA - epididymis [nTPM]":"24.7","Tissue RNA - esophagus [nTPM]":"28.9","Tissue RNA - fallopian tube [nTPM]":"26.8","Tissue RNA - gallbladder [nTPM]":"33.0","Tissue RNA - heart muscle [nTPM]":"39.3","Tissue RNA - hippocampal formation [nTPM]":"18.3","Tissue RNA - hypothalamus [nTPM]":"14.4","Tissue RNA - kidney [nTPM]":"26.6","Tissue RNA - liver [nTPM]":"25.7","Tissue RNA - lung [nTPM]":"26.3","Tissue RNA - lymph node [nTPM]":"24.0","Tissue RNA - medulla oblongata [nTPM]":"16.9","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"25.7","Tissue RNA - pancreas [nTPM]":"28.4","Tissue RNA - parathyroid gland [nTPM]":"26.3","Tissue RNA - pituitary gland [nTPM]":"26.5","Tissue RNA - placenta [nTPM]":"27.5","Tissue RNA - pons [nTPM]":"17.1","Tissue RNA - prostate [nTPM]":"28.1","Tissue RNA - rectum [nTPM]":"14.8","Tissue RNA - retina [nTPM]":"11.3","Tissue RNA - salivary gland [nTPM]":"70.0","Tissue RNA - seminal vesicle [nTPM]":"18.7","Tissue RNA - skeletal muscle [nTPM]":"25.1","Tissue RNA - skin 1 [nTPM]":"23.3","Tissue RNA - small intestine [nTPM]":"23.3","Tissue RNA - smooth muscle [nTPM]":"21.6","Tissue RNA - spinal cord [nTPM]":"11.1","Tissue RNA - spleen [nTPM]":"34.6","Tissue RNA - stomach 1 [nTPM]":"30.6","Tissue RNA - testis [nTPM]":"24.5","Tissue RNA - thalamus [nTPM]":"14.7","Tissue RNA - thymus [nTPM]":"51.7","Tissue RNA - thyroid gland [nTPM]":"36.7","Tissue RNA - tongue [nTPM]":"18.5","Tissue RNA - tonsil [nTPM]":"21.1","Tissue RNA - urinary bladder [nTPM]":"26.1","Tissue RNA - vagina [nTPM]":"26.6","Tissue RNA - white matter [nTPM]":"16.9","Cell RNA - A-431 [nTPM]":"63.1","Cell RNA - A549 [nTPM]":"61.9","Cell RNA - AF22 [nTPM]":"63.9","Cell RNA - AN3-CA [nTPM]":"89.8","Cell RNA - ASC diff [nTPM]":"36.9","Cell RNA - ASC TERT1 [nTPM]":"40.5","Cell RNA - BEWO [nTPM]":"65.3","Cell RNA - BJ [nTPM]":"37.0","Cell RNA - BJ hTERT+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.2","Cell RNA - CACO-2 [nTPM]":"34.9","Cell RNA - CAPAN-2 [nTPM]":"16.6","Cell RNA - Daudi [nTPM]":"36.7","Cell RNA - EFO-21 [nTPM]":"34.3","Cell RNA - fHDF\/TERT166 [nTPM]":"44.3","Cell RNA - GAMG [nTPM]":"52.0","Cell RNA - HaCaT [nTPM]":"64.8","Cell RNA - HAP1 [nTPM]":"144.6","Cell RNA - HBEC3-KT [nTPM]":"36.0","Cell RNA - HBF TERT88 [nTPM]":"34.5","Cell RNA - HDLM-2 [nTPM]":"46.7","Cell RNA - HEK 293 [nTPM]":"56.7","Cell RNA - HEL [nTPM]":"85.8","Cell RNA - HeLa [nTPM]":"52.8","Cell RNA - Hep G2 [nTPM]":"46.1","Cell RNA - HHSteC [nTPM]":"23.9","Cell RNA - HL-60 [nTPM]":"30.8","Cell RNA - HMC-1 [nTPM]":"60.9","Cell RNA - HSkMC [nTPM]":"33.8","Cell RNA - hTCEpi [nTPM]":"26.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.5","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"28.4","Cell RNA - HUVEC TERT2 [nTPM]":"122.6","Cell RNA - JURKAT [nTPM]":"68.5","Cell RNA - K-562 [nTPM]":"47.2","Cell RNA - Karpas-707 [nTPM]":"14.9","Cell RNA - LHCN-M2 [nTPM]":"35.1","Cell RNA - MCF7 [nTPM]":"70.9","Cell RNA - MOLT-4 [nTPM]":"204.4","Cell RNA - NB-4 [nTPM]":"19.4","Cell RNA - NTERA-2 [nTPM]":"30.1","Cell RNA - OE19 [nTPM]":"32.2","Cell RNA - PC-3 [nTPM]":"45.0","Cell RNA - REH [nTPM]":"107.9","Cell RNA - RH-30 [nTPM]":"71.7","Cell RNA - RPMI-8226 [nTPM]":"23.1","Cell RNA - RPTEC TERT1 [nTPM]":"28.5","Cell RNA - RT4 [nTPM]":"59.2","Cell RNA - SCLC-21H [nTPM]":"61.5","Cell RNA - SH-SY5Y [nTPM]":"70.9","Cell RNA - SiHa [nTPM]":"40.0","Cell RNA - SK-BR-3 [nTPM]":"70.0","Cell RNA - SK-MEL-30 [nTPM]":"24.6","Cell RNA - SuSa [nTPM]":"39.7","Cell RNA - T-47d [nTPM]":"52.7","Cell RNA - THP-1 [nTPM]":"18.7","Cell RNA - TIME [nTPM]":"52.8","Cell RNA - U-138 MG [nTPM]":"75.9","Cell RNA - U-2 OS [nTPM]":"56.8","Cell RNA - U-2197 [nTPM]":"48.2","Cell RNA - U-251 MG [nTPM]":"60.4","Cell RNA - U-266\/70 [nTPM]":"21.1","Cell RNA - U-266\/84 [nTPM]":"17.2","Cell RNA - U-698 [nTPM]":"40.7","Cell RNA - U-87 MG [nTPM]":"47.3","Cell RNA - U-937 [nTPM]":"37.7","Cell RNA - WM-115 [nTPM]":"29.5","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"17.7","Blood RNA - eosinophil [nTPM]":"9.6","Blood RNA - gdT-cell [nTPM]":"23.4","Blood RNA - intermediate monocyte [nTPM]":"41.3","Blood RNA - MAIT T-cell [nTPM]":"28.6","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"21.0","Blood RNA - memory CD8 T-cell [nTPM]":"24.7","Blood RNA - myeloid DC [nTPM]":"15.4","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"8.6","Blood RNA - naive CD8 T-cell [nTPM]":"10.4","Blood RNA - neutrophil [nTPM]":"3.7","Blood RNA - NK-cell [nTPM]":"18.2","Blood RNA - non-classical monocyte [nTPM]":"51.7","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"16.8","Blood RNA - total PBMC [nTPM]":"16.9","Brain RNA - amygdala [nTPM]":"17.6","Brain RNA - basal ganglia [nTPM]":"19.0","Brain RNA - cerebellum [nTPM]":"12.1","Brain RNA - cerebral cortex [nTPM]":"17.6","Brain RNA - hippocampal formation [nTPM]":"18.3","Brain RNA - hypothalamus [nTPM]":"14.4","Brain RNA - medulla oblongata [nTPM]":"16.9","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"17.1","Brain RNA - spinal cord [nTPM]":"11.1","Brain RNA - thalamus [nTPM]":"14.7","Brain RNA - white matter [nTPM]":"16.9","Single Cell Type RNA - Adipocytes [nTPM]":"50.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"43.2","Single Cell Type RNA - Astrocytes [nTPM]":"31.0","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"15.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.8","Single Cell Type RNA - dendritic cells [nTPM]":"14.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"12.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.7","Single Cell Type RNA - Endothelial cells [nTPM]":"34.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"24.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.9","Single Cell Type RNA - Fibroblasts [nTPM]":"18.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.5","Single Cell Type RNA - granulocytes [nTPM]":"38.1","Single Cell Type RNA - Granulosa cells [nTPM]":"30.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"26.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.7","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.0","Single Cell Type RNA - Late spermatids [nTPM]":"20.8","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"10.8","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"45.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"16.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"15.9","Single Cell Type RNA - Spermatogonia [nTPM]":"21.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.7","Single Cell Type RNA - T-cells [nTPM]":"29.3","Single Cell Type RNA - Theca cells [nTPM]":"21.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.3","Single Cell Type RNA - Urothelial cells [nTPM]":"12.1"},{"Gene":"TBK1","Gene synonym":["NAK"],"Ensembl":"ENSG00000183735","Gene description":"TANK binding kinase 1","Uniprot":["Q9UHD2"],"Chromosome":"12","Position":"64452090-64502114","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Glaucoma","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045797","HPA060211"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA045797":"AB_2679457","HPA060211":"AB_2684222"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.30e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.48e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.20e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"15.3","Tissue RNA - amygdala [nTPM]":"6.0","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"6.1","Tissue RNA - bone marrow [nTPM]":"16.9","Tissue RNA - breast [nTPM]":"11.4","Tissue RNA - cerebellum [nTPM]":"5.6","Tissue RNA - cerebral cortex [nTPM]":"6.9","Tissue RNA - cervix [nTPM]":"10.6","Tissue RNA - choroid plexus [nTPM]":"5.3","Tissue RNA - colon [nTPM]":"10.5","Tissue RNA - duodenum [nTPM]":"15.1","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"6.7","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"10.1","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"11.8","Tissue RNA - liver [nTPM]":"17.4","Tissue RNA - lung [nTPM]":"12.9","Tissue RNA - lymph node [nTPM]":"14.6","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"6.9","Tissue RNA - ovary [nTPM]":"9.6","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"11.6","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"13.7","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"10.6","Tissue RNA - rectum [nTPM]":"8.5","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"10.2","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"8.6","Tissue RNA - small intestine [nTPM]":"11.4","Tissue RNA - smooth muscle [nTPM]":"10.8","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"13.4","Tissue RNA - stomach 1 [nTPM]":"10.2","Tissue RNA - testis [nTPM]":"23.5","Tissue RNA - thalamus [nTPM]":"6.7","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"14.9","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"16.0","Tissue RNA - vagina [nTPM]":"10.2","Tissue RNA - white matter [nTPM]":"7.1","Cell RNA - A-431 [nTPM]":"23.3","Cell RNA - A549 [nTPM]":"24.2","Cell RNA - AF22 [nTPM]":"11.1","Cell RNA - AN3-CA [nTPM]":"10.6","Cell RNA - ASC diff [nTPM]":"24.7","Cell RNA - ASC TERT1 [nTPM]":"26.1","Cell RNA - BEWO [nTPM]":"29.0","Cell RNA - BJ [nTPM]":"22.9","Cell RNA - BJ hTERT+ [nTPM]":"37.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.1","Cell RNA - CACO-2 [nTPM]":"14.9","Cell RNA - CAPAN-2 [nTPM]":"12.4","Cell RNA - Daudi [nTPM]":"31.5","Cell RNA - EFO-21 [nTPM]":"21.4","Cell RNA - fHDF\/TERT166 [nTPM]":"26.8","Cell RNA - GAMG [nTPM]":"34.4","Cell RNA - HaCaT [nTPM]":"19.0","Cell RNA - HAP1 [nTPM]":"19.4","Cell RNA - HBEC3-KT [nTPM]":"20.0","Cell RNA - HBF TERT88 [nTPM]":"26.4","Cell RNA - HDLM-2 [nTPM]":"29.5","Cell RNA - HEK 293 [nTPM]":"17.1","Cell RNA - HEL [nTPM]":"33.0","Cell RNA - HeLa [nTPM]":"15.3","Cell RNA - Hep G2 [nTPM]":"19.1","Cell RNA - HHSteC [nTPM]":"30.2","Cell RNA - HL-60 [nTPM]":"35.2","Cell RNA - HMC-1 [nTPM]":"36.4","Cell RNA - HSkMC [nTPM]":"18.5","Cell RNA - hTCEpi [nTPM]":"19.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.1","Cell RNA - hTERT-HME1 [nTPM]":"23.6","Cell RNA - hTERT-RPE1 [nTPM]":"42.3","Cell RNA - HUVEC TERT2 [nTPM]":"32.4","Cell RNA - JURKAT [nTPM]":"11.0","Cell RNA - K-562 [nTPM]":"27.9","Cell RNA - Karpas-707 [nTPM]":"38.7","Cell RNA - LHCN-M2 [nTPM]":"31.6","Cell RNA - MCF7 [nTPM]":"27.0","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"17.0","Cell RNA - NTERA-2 [nTPM]":"29.9","Cell RNA - OE19 [nTPM]":"22.9","Cell RNA - PC-3 [nTPM]":"13.8","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"15.3","Cell RNA - RPMI-8226 [nTPM]":"31.8","Cell RNA - RPTEC TERT1 [nTPM]":"25.1","Cell RNA - RT4 [nTPM]":"36.9","Cell RNA - SCLC-21H [nTPM]":"9.8","Cell RNA - SH-SY5Y [nTPM]":"14.7","Cell RNA - SiHa [nTPM]":"33.3","Cell RNA - SK-BR-3 [nTPM]":"36.0","Cell RNA - SK-MEL-30 [nTPM]":"23.5","Cell RNA - SuSa [nTPM]":"23.5","Cell RNA - T-47d [nTPM]":"33.1","Cell RNA - THP-1 [nTPM]":"24.9","Cell RNA - TIME [nTPM]":"25.9","Cell RNA - U-138 MG [nTPM]":"20.2","Cell RNA - U-2 OS [nTPM]":"18.1","Cell RNA - U-2197 [nTPM]":"14.9","Cell RNA - U-251 MG [nTPM]":"24.0","Cell RNA - U-266\/70 [nTPM]":"25.4","Cell RNA - U-266\/84 [nTPM]":"54.3","Cell RNA - U-698 [nTPM]":"30.3","Cell RNA - U-87 MG [nTPM]":"28.1","Cell RNA - U-937 [nTPM]":"18.6","Cell RNA - WM-115 [nTPM]":"26.1","Blood RNA - basophil [nTPM]":"41.8","Blood RNA - classical monocyte [nTPM]":"10.1","Blood RNA - eosinophil [nTPM]":"24.3","Blood RNA - gdT-cell [nTPM]":"13.9","Blood RNA - intermediate monocyte [nTPM]":"17.7","Blood RNA - MAIT T-cell [nTPM]":"16.3","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"15.2","Blood RNA - myeloid DC [nTPM]":"12.2","Blood RNA - naive B-cell [nTPM]":"10.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"8.7","Blood RNA - neutrophil [nTPM]":"17.8","Blood RNA - NK-cell [nTPM]":"26.6","Blood RNA - non-classical monocyte [nTPM]":"15.5","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"13.6","Blood RNA - total PBMC [nTPM]":"10.0","Brain RNA - amygdala [nTPM]":"6.0","Brain RNA - basal ganglia [nTPM]":"6.1","Brain RNA - cerebellum [nTPM]":"5.6","Brain RNA - cerebral cortex [nTPM]":"6.9","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"6.9","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"6.7","Brain RNA - white matter [nTPM]":"7.1","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.5","Single Cell Type RNA - Astrocytes [nTPM]":"28.4","Single Cell Type RNA - B-cells [nTPM]":"21.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"17.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"23.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.8","Single Cell Type RNA - dendritic cells [nTPM]":"30.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"34.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.9","Single Cell Type RNA - Endothelial cells [nTPM]":"28.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.3","Single Cell Type RNA - Erythroid cells [nTPM]":"18.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.6","Single Cell Type RNA - Fibroblasts [nTPM]":"21.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.2","Single Cell Type RNA - granulocytes [nTPM]":"43.1","Single Cell Type RNA - Granulosa cells [nTPM]":"17.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"17.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.5","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.0","Single Cell Type RNA - Langerhans cells [nTPM]":"30.2","Single Cell Type RNA - Late spermatids [nTPM]":"29.2","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"31.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"46.9","Single Cell Type RNA - monocytes [nTPM]":"31.4","Single Cell Type RNA - Muller glia cells [nTPM]":"12.7","Single Cell Type RNA - NK-cells [nTPM]":"33.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"52.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"10.9","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"25.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.7","Single Cell Type RNA - Spermatocytes [nTPM]":"68.9","Single Cell Type RNA - Spermatogonia [nTPM]":"12.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"92.6","Single Cell Type RNA - T-cells [nTPM]":"27.1","Single Cell Type RNA - Theca cells [nTPM]":"11.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.1","Single Cell Type RNA - Urothelial cells [nTPM]":"41.6"},{"Gene":"TBL1Y","Gene synonym":["TBL1"],"Ensembl":"ENSG00000092377","Gene description":"Transducin beta like 1 Y-linked","Uniprot":["Q9BQ87"],"Chromosome":"Y","Position":"6910686-7101970","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Activator"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"2.9","thyroid gland":"1.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"3.4","Inhibitory neurons":"2.2","Oligodendrocyte precursor cells":"1.0","Squamous epithelial cells":"5.7","Urothelial cells":"1.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"prostate cancer":"1.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"1.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"U-698":"12.3"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050857","HPA060073"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA050857":null,"HPA060073":"AB_2684196"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"2.9","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"12.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"TBP","Gene synonym":["GTF2D1","SCA17","TFIID"],"Ensembl":"ENSG00000112592","Gene description":"TATA-box binding protein","Uniprot":["P20226"],"Chromosome":"6","Position":"170554302-170572870","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"88.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009442","HPA049805"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB009442":"AB_632480","HPA049805":"AB_2680890"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.51e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"10.5","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"9.6","Tissue RNA - basal ganglia [nTPM]":"9.6","Tissue RNA - bone marrow [nTPM]":"15.6","Tissue RNA - breast [nTPM]":"10.4","Tissue RNA - cerebellum [nTPM]":"10.8","Tissue RNA - cerebral cortex [nTPM]":"15.1","Tissue RNA - cervix [nTPM]":"10.5","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"8.5","Tissue RNA - endometrium 1 [nTPM]":"12.6","Tissue RNA - epididymis [nTPM]":"8.1","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"11.0","Tissue RNA - liver [nTPM]":"11.5","Tissue RNA - lung [nTPM]":"9.7","Tissue RNA - lymph node [nTPM]":"14.0","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"11.7","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"10.8","Tissue RNA - pons [nTPM]":"10.2","Tissue RNA - prostate [nTPM]":"10.5","Tissue RNA - rectum [nTPM]":"8.5","Tissue RNA - retina [nTPM]":"8.9","Tissue RNA - salivary gland [nTPM]":"10.3","Tissue RNA - seminal vesicle [nTPM]":"7.6","Tissue RNA - skeletal muscle [nTPM]":"12.8","Tissue RNA - skin 1 [nTPM]":"10.7","Tissue RNA - small intestine [nTPM]":"11.9","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"8.7","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"11.7","Tissue RNA - testis [nTPM]":"34.5","Tissue RNA - thalamus [nTPM]":"9.7","Tissue RNA - thymus [nTPM]":"11.9","Tissue RNA - thyroid gland [nTPM]":"10.5","Tissue RNA - tongue [nTPM]":"10.6","Tissue RNA - tonsil [nTPM]":"12.2","Tissue RNA - urinary bladder [nTPM]":"10.6","Tissue RNA - vagina [nTPM]":"10.8","Tissue RNA - white matter [nTPM]":"12.3","Cell RNA - A-431 [nTPM]":"12.9","Cell RNA - A549 [nTPM]":"14.0","Cell RNA - AF22 [nTPM]":"24.4","Cell RNA - AN3-CA [nTPM]":"31.2","Cell RNA - ASC diff [nTPM]":"12.5","Cell RNA - ASC TERT1 [nTPM]":"14.2","Cell RNA - BEWO [nTPM]":"23.0","Cell RNA - BJ [nTPM]":"20.5","Cell RNA - BJ hTERT+ [nTPM]":"15.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.1","Cell RNA - CACO-2 [nTPM]":"28.9","Cell RNA - CAPAN-2 [nTPM]":"12.7","Cell RNA - Daudi [nTPM]":"27.1","Cell RNA - EFO-21 [nTPM]":"16.4","Cell RNA - fHDF\/TERT166 [nTPM]":"16.7","Cell RNA - GAMG [nTPM]":"28.6","Cell RNA - HaCaT [nTPM]":"18.9","Cell RNA - HAP1 [nTPM]":"31.6","Cell RNA - HBEC3-KT [nTPM]":"16.8","Cell RNA - HBF TERT88 [nTPM]":"21.2","Cell RNA - HDLM-2 [nTPM]":"31.5","Cell RNA - HEK 293 [nTPM]":"23.2","Cell RNA - HEL [nTPM]":"27.6","Cell RNA - HeLa [nTPM]":"16.6","Cell RNA - Hep G2 [nTPM]":"26.1","Cell RNA - HHSteC [nTPM]":"18.1","Cell RNA - HL-60 [nTPM]":"32.7","Cell RNA - HMC-1 [nTPM]":"23.1","Cell RNA - HSkMC [nTPM]":"13.8","Cell RNA - hTCEpi [nTPM]":"19.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.9","Cell RNA - hTERT-HME1 [nTPM]":"25.8","Cell RNA - hTERT-RPE1 [nTPM]":"16.3","Cell RNA - HUVEC TERT2 [nTPM]":"15.9","Cell RNA - JURKAT [nTPM]":"37.2","Cell RNA - K-562 [nTPM]":"49.7","Cell RNA - Karpas-707 [nTPM]":"16.5","Cell RNA - LHCN-M2 [nTPM]":"18.3","Cell RNA - MCF7 [nTPM]":"19.3","Cell RNA - MOLT-4 [nTPM]":"32.8","Cell RNA - NB-4 [nTPM]":"31.8","Cell RNA - NTERA-2 [nTPM]":"24.5","Cell RNA - OE19 [nTPM]":"27.3","Cell RNA - PC-3 [nTPM]":"11.0","Cell RNA - REH [nTPM]":"28.6","Cell RNA - RH-30 [nTPM]":"20.0","Cell RNA - RPMI-8226 [nTPM]":"23.8","Cell RNA - RPTEC TERT1 [nTPM]":"14.5","Cell RNA - RT4 [nTPM]":"6.5","Cell RNA - SCLC-21H [nTPM]":"10.4","Cell RNA - SH-SY5Y [nTPM]":"24.9","Cell RNA - SiHa [nTPM]":"24.1","Cell RNA - SK-BR-3 [nTPM]":"17.8","Cell RNA - SK-MEL-30 [nTPM]":"16.0","Cell RNA - SuSa [nTPM]":"20.7","Cell RNA - T-47d [nTPM]":"12.4","Cell RNA - THP-1 [nTPM]":"40.7","Cell RNA - TIME [nTPM]":"17.6","Cell RNA - U-138 MG [nTPM]":"13.5","Cell RNA - U-2 OS [nTPM]":"19.1","Cell RNA - U-2197 [nTPM]":"22.2","Cell RNA - U-251 MG [nTPM]":"32.0","Cell RNA - U-266\/70 [nTPM]":"24.4","Cell RNA - U-266\/84 [nTPM]":"35.1","Cell RNA - U-698 [nTPM]":"42.3","Cell RNA - U-87 MG [nTPM]":"18.5","Cell RNA - U-937 [nTPM]":"27.0","Cell RNA - WM-115 [nTPM]":"21.9","Blood RNA - basophil [nTPM]":"67.4","Blood RNA - classical monocyte [nTPM]":"30.8","Blood RNA - eosinophil [nTPM]":"39.8","Blood RNA - gdT-cell [nTPM]":"37.8","Blood RNA - intermediate monocyte [nTPM]":"32.2","Blood RNA - MAIT T-cell [nTPM]":"44.4","Blood RNA - memory B-cell [nTPM]":"52.9","Blood RNA - memory CD4 T-cell [nTPM]":"36.7","Blood RNA - memory CD8 T-cell [nTPM]":"38.6","Blood RNA - myeloid DC [nTPM]":"30.2","Blood RNA - naive B-cell [nTPM]":"49.9","Blood RNA - naive CD4 T-cell [nTPM]":"47.3","Blood RNA - naive CD8 T-cell [nTPM]":"40.0","Blood RNA - neutrophil [nTPM]":"44.4","Blood RNA - NK-cell [nTPM]":"35.0","Blood RNA - non-classical monocyte [nTPM]":"45.4","Blood RNA - plasmacytoid DC [nTPM]":"42.6","Blood RNA - T-reg [nTPM]":"37.2","Blood RNA - total PBMC [nTPM]":"21.8","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"9.6","Brain RNA - cerebellum [nTPM]":"10.8","Brain RNA - cerebral cortex [nTPM]":"15.1","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"10.2","Brain RNA - spinal cord [nTPM]":"8.7","Brain RNA - thalamus [nTPM]":"9.7","Brain RNA - white matter [nTPM]":"12.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"16.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"7.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.8","Single Cell Type RNA - dendritic cells [nTPM]":"10.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"26.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.3","Single Cell Type RNA - Endothelial cells [nTPM]":"9.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.5","Single Cell Type RNA - Fibroblasts [nTPM]":"9.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"13.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.5","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"14.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"7.7","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"9.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"8.5","Single Cell Type RNA - Muller glia cells [nTPM]":"5.4","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.9","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.1","Single Cell Type RNA - Spermatocytes [nTPM]":"88.1","Single Cell Type RNA - Spermatogonia [nTPM]":"17.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.5","Single Cell Type RNA - T-cells [nTPM]":"11.1","Single Cell Type RNA - Theca cells [nTPM]":"10.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.7"},{"Gene":"TCF4","Gene synonym":["bHLHb19","E2-2","ITF2","SEF2-1B"],"Ensembl":"ENSG00000196628","Gene description":"Transcription factor 4","Uniprot":["P15884"],"Chromosome":"18","Position":"55222185-55664787","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Corneal dystrophy","Disease variant","Epilepsy","Mental retardation","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"65.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"820.0","Endothelial cells":"574.5","Inhibitory neurons":"1177.6","Oligodendrocyte precursor cells":"719.8","Oligodendrocytes":"573.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"65.1"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"memory B-cell":"173.6","naive B-cell":"146.8","plasmacytoid DC":"559.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"B-cells":"173.6","dendritic cells":"559.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"140.4","SH-SY5Y":"157.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020722","HPA025958"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB020722":null,"HPA025958":"AB_1857849"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.24e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.95e-4"},"Tissue RNA - adipose tissue [nTPM]":"20.3","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"12.8","Tissue RNA - basal ganglia [nTPM]":"12.5","Tissue RNA - bone marrow [nTPM]":"9.5","Tissue RNA - breast [nTPM]":"11.6","Tissue RNA - cerebellum [nTPM]":"65.1","Tissue RNA - cerebral cortex [nTPM]":"26.5","Tissue RNA - cervix [nTPM]":"28.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"23.0","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"9.7","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"17.4","Tissue RNA - heart muscle [nTPM]":"17.5","Tissue RNA - hippocampal formation [nTPM]":"29.8","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"4.4","Tissue RNA - lung [nTPM]":"15.5","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"25.9","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"28.9","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"14.0","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"10.2","Tissue RNA - skeletal muscle [nTPM]":"6.1","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"5.0","Tissue RNA - smooth muscle [nTPM]":"24.1","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"13.1","Tissue RNA - stomach 1 [nTPM]":"6.0","Tissue RNA - testis [nTPM]":"15.4","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"14.7","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"14.4","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"4.1","Cell RNA - AF22 [nTPM]":"36.8","Cell RNA - AN3-CA [nTPM]":"11.4","Cell RNA - ASC diff [nTPM]":"8.5","Cell RNA - ASC TERT1 [nTPM]":"14.4","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"18.4","Cell RNA - BJ hTERT+ [nTPM]":"40.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.2","Cell RNA - CACO-2 [nTPM]":"23.1","Cell RNA - CAPAN-2 [nTPM]":"3.6","Cell RNA - Daudi [nTPM]":"28.8","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"41.9","Cell RNA - GAMG [nTPM]":"2.7","Cell RNA - HaCaT [nTPM]":"4.5","Cell RNA - HAP1 [nTPM]":"17.9","Cell RNA - HBEC3-KT [nTPM]":"17.1","Cell RNA - HBF TERT88 [nTPM]":"9.2","Cell RNA - HDLM-2 [nTPM]":"140.4","Cell RNA - HEK 293 [nTPM]":"13.9","Cell RNA - HEL [nTPM]":"12.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"4.0","Cell RNA - HL-60 [nTPM]":"5.3","Cell RNA - HMC-1 [nTPM]":"2.8","Cell RNA - HSkMC [nTPM]":"19.6","Cell RNA - hTCEpi [nTPM]":"5.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.5","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"9.1","Cell RNA - HUVEC TERT2 [nTPM]":"45.8","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"19.5","Cell RNA - Karpas-707 [nTPM]":"22.0","Cell RNA - LHCN-M2 [nTPM]":"11.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"7.6","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"41.6","Cell RNA - RH-30 [nTPM]":"14.9","Cell RNA - RPMI-8226 [nTPM]":"65.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"12.6","Cell RNA - SH-SY5Y [nTPM]":"157.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"11.1","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"49.1","Cell RNA - U-138 MG [nTPM]":"48.5","Cell RNA - U-2 OS [nTPM]":"17.4","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"14.6","Cell RNA - U-266\/70 [nTPM]":"16.3","Cell RNA - U-266\/84 [nTPM]":"32.2","Cell RNA - U-698 [nTPM]":"25.7","Cell RNA - U-87 MG [nTPM]":"11.0","Cell RNA - U-937 [nTPM]":"5.2","Cell RNA - WM-115 [nTPM]":"15.5","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"7.4","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"8.3","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"173.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"20.6","Blood RNA - naive B-cell [nTPM]":"146.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"11.2","Blood RNA - non-classical monocyte [nTPM]":"7.4","Blood RNA - plasmacytoid DC [nTPM]":"559.8","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"11.3","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"12.5","Brain RNA - cerebellum [nTPM]":"65.1","Brain RNA - cerebral cortex [nTPM]":"26.5","Brain RNA - hippocampal formation [nTPM]":"29.8","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"14.4","Single Cell Type RNA - Adipocytes [nTPM]":"820.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"501.1","Single Cell Type RNA - B-cells [nTPM]":"217.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"117.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"80.8","Single Cell Type RNA - Bipolar cells [nTPM]":"293.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"32.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"83.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - dendritic cells [nTPM]":"446.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"103.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"201.4","Single Cell Type RNA - Endothelial cells [nTPM]":"574.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"34.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"503.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"296.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.2","Single Cell Type RNA - granulocytes [nTPM]":"13.9","Single Cell Type RNA - Granulosa cells [nTPM]":"105.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"316.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.6","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1177.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"112.4","Single Cell Type RNA - Langerhans cells [nTPM]":"129.2","Single Cell Type RNA - Late spermatids [nTPM]":"116.3","Single Cell Type RNA - Leydig cells [nTPM]":"205.3","Single Cell Type RNA - Macrophages [nTPM]":"80.4","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"474.1","Single Cell Type RNA - monocytes [nTPM]":"32.7","Single Cell Type RNA - Muller glia cells [nTPM]":"372.8","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"719.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"573.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"182.1","Single Cell Type RNA - Plasma cells [nTPM]":"131.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"54.7","Single Cell Type RNA - Sertoli cells [nTPM]":"236.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"304.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"221.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"14.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"47.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"15.1","Single Cell Type RNA - Theca cells [nTPM]":"164.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"17.8"},{"Gene":"TDP1","Gene synonym":["FLJ11090","SCAN1"],"Ensembl":"ENSG00000042088","Gene description":"Tyrosyl-DNA phosphodiesterase 1","Uniprot":["Q9NUW8"],"Chromosome":"14","Position":"89954939-90044764","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Exonuclease","Hydrolase","Nuclease"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"123.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071317"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA071317":"AB_2686388"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.99e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.5","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"11.8","Tissue RNA - basal ganglia [nTPM]":"4.5","Tissue RNA - bone marrow [nTPM]":"13.9","Tissue RNA - breast [nTPM]":"8.9","Tissue RNA - cerebellum [nTPM]":"6.6","Tissue RNA - cerebral cortex [nTPM]":"4.9","Tissue RNA - cervix [nTPM]":"6.6","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"7.8","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"5.9","Tissue RNA - epididymis [nTPM]":"5.8","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"9.2","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"2.6","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"6.5","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"19.0","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"5.1","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"10.1","Tissue RNA - retina [nTPM]":"4.9","Tissue RNA - salivary gland [nTPM]":"5.5","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"10.6","Tissue RNA - stomach 1 [nTPM]":"7.9","Tissue RNA - testis [nTPM]":"22.3","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"28.3","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"23.7","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"33.8","Cell RNA - A549 [nTPM]":"18.6","Cell RNA - AF22 [nTPM]":"40.9","Cell RNA - AN3-CA [nTPM]":"37.5","Cell RNA - ASC diff [nTPM]":"10.1","Cell RNA - ASC TERT1 [nTPM]":"14.0","Cell RNA - BEWO [nTPM]":"32.7","Cell RNA - BJ [nTPM]":"31.7","Cell RNA - BJ hTERT+ [nTPM]":"25.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.6","Cell RNA - CACO-2 [nTPM]":"13.6","Cell RNA - CAPAN-2 [nTPM]":"35.5","Cell RNA - Daudi [nTPM]":"42.9","Cell RNA - EFO-21 [nTPM]":"23.3","Cell RNA - fHDF\/TERT166 [nTPM]":"21.7","Cell RNA - GAMG [nTPM]":"12.9","Cell RNA - HaCaT [nTPM]":"33.9","Cell RNA - HAP1 [nTPM]":"18.2","Cell RNA - HBEC3-KT [nTPM]":"29.5","Cell RNA - HBF TERT88 [nTPM]":"55.2","Cell RNA - HDLM-2 [nTPM]":"44.1","Cell RNA - HEK 293 [nTPM]":"19.6","Cell RNA - HEL [nTPM]":"43.9","Cell RNA - HeLa [nTPM]":"16.7","Cell RNA - Hep G2 [nTPM]":"16.6","Cell RNA - HHSteC [nTPM]":"8.7","Cell RNA - HL-60 [nTPM]":"73.2","Cell RNA - HMC-1 [nTPM]":"24.1","Cell RNA - HSkMC [nTPM]":"10.1","Cell RNA - hTCEpi [nTPM]":"12.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.9","Cell RNA - hTERT-HME1 [nTPM]":"24.9","Cell RNA - hTERT-RPE1 [nTPM]":"21.9","Cell RNA - HUVEC TERT2 [nTPM]":"49.5","Cell RNA - JURKAT [nTPM]":"57.3","Cell RNA - K-562 [nTPM]":"30.6","Cell RNA - Karpas-707 [nTPM]":"43.5","Cell RNA - LHCN-M2 [nTPM]":"45.9","Cell RNA - MCF7 [nTPM]":"35.0","Cell RNA - MOLT-4 [nTPM]":"56.3","Cell RNA - NB-4 [nTPM]":"39.2","Cell RNA - NTERA-2 [nTPM]":"10.0","Cell RNA - OE19 [nTPM]":"39.8","Cell RNA - PC-3 [nTPM]":"43.7","Cell RNA - REH [nTPM]":"42.3","Cell RNA - RH-30 [nTPM]":"77.3","Cell RNA - RPMI-8226 [nTPM]":"34.0","Cell RNA - RPTEC TERT1 [nTPM]":"24.6","Cell RNA - RT4 [nTPM]":"27.3","Cell RNA - SCLC-21H [nTPM]":"30.7","Cell RNA - SH-SY5Y [nTPM]":"20.9","Cell RNA - SiHa [nTPM]":"26.9","Cell RNA - SK-BR-3 [nTPM]":"77.6","Cell RNA - SK-MEL-30 [nTPM]":"10.1","Cell RNA - SuSa [nTPM]":"27.0","Cell RNA - T-47d [nTPM]":"31.0","Cell RNA - THP-1 [nTPM]":"30.8","Cell RNA - TIME [nTPM]":"39.9","Cell RNA - U-138 MG [nTPM]":"16.5","Cell RNA - U-2 OS [nTPM]":"15.7","Cell RNA - U-2197 [nTPM]":"23.0","Cell RNA - U-251 MG [nTPM]":"28.7","Cell RNA - U-266\/70 [nTPM]":"31.8","Cell RNA - U-266\/84 [nTPM]":"60.4","Cell RNA - U-698 [nTPM]":"52.3","Cell RNA - U-87 MG [nTPM]":"35.5","Cell RNA - U-937 [nTPM]":"32.3","Cell RNA - WM-115 [nTPM]":"24.6","Blood RNA - basophil [nTPM]":"28.7","Blood RNA - classical monocyte [nTPM]":"8.9","Blood RNA - eosinophil [nTPM]":"15.1","Blood RNA - gdT-cell [nTPM]":"18.8","Blood RNA - intermediate monocyte [nTPM]":"14.6","Blood RNA - MAIT T-cell [nTPM]":"18.3","Blood RNA - memory B-cell [nTPM]":"21.1","Blood RNA - memory CD4 T-cell [nTPM]":"19.8","Blood RNA - memory CD8 T-cell [nTPM]":"20.8","Blood RNA - myeloid DC [nTPM]":"14.2","Blood RNA - naive B-cell [nTPM]":"20.0","Blood RNA - naive CD4 T-cell [nTPM]":"21.7","Blood RNA - naive CD8 T-cell [nTPM]":"23.1","Blood RNA - neutrophil [nTPM]":"5.7","Blood RNA - NK-cell [nTPM]":"23.8","Blood RNA - non-classical monocyte [nTPM]":"14.1","Blood RNA - plasmacytoid DC [nTPM]":"15.0","Blood RNA - T-reg [nTPM]":"32.2","Blood RNA - total PBMC [nTPM]":"14.8","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"4.5","Brain RNA - cerebellum [nTPM]":"6.6","Brain RNA - cerebral cortex [nTPM]":"4.9","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"2.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"15.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - dendritic cells [nTPM]":"14.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.2","Single Cell Type RNA - Early spermatids [nTPM]":"123.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.9","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"4.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.8","Single Cell Type RNA - Langerhans cells [nTPM]":"10.2","Single Cell Type RNA - Late spermatids [nTPM]":"36.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"8.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"4.8","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"16.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.4","Single Cell Type RNA - Spermatocytes [nTPM]":"33.7","Single Cell Type RNA - Spermatogonia [nTPM]":"22.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - T-cells [nTPM]":"15.0","Single Cell Type RNA - Theca cells [nTPM]":"10.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.0"},{"Gene":"TDP2","Gene synonym":["TTRAP"],"Ensembl":"ENSG00000111802","Gene description":"Tyrosyl-DNA phosphodiesterase 2","Uniprot":["O95551"],"Chromosome":"6","Position":"24649979-24666930","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction"],"Molecular function":["Hydrolase","Nuclease"],"Disease involvement":["Mental retardation","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"183.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"530.9","Paneth cells":"428.1","Proximal enterocytes":"637.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"75.6","neutrophil":"228.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"228.9"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB073398","HPA074011"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB073398":null,"HPA074011":"AB_2686651"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.53e-7"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.47e-5"},"Tissue RNA - adipose tissue [nTPM]":"24.4","Tissue RNA - adrenal gland [nTPM]":"23.7","Tissue RNA - amygdala [nTPM]":"27.4","Tissue RNA - appendix [nTPM]":"34.3","Tissue RNA - basal ganglia [nTPM]":"28.4","Tissue RNA - bone marrow [nTPM]":"21.8","Tissue RNA - breast [nTPM]":"27.3","Tissue RNA - cerebellum [nTPM]":"30.4","Tissue RNA - cerebral cortex [nTPM]":"36.4","Tissue RNA - cervix [nTPM]":"20.6","Tissue RNA - choroid plexus [nTPM]":"30.4","Tissue RNA - colon [nTPM]":"141.6","Tissue RNA - duodenum [nTPM]":"120.1","Tissue RNA - endometrium 1 [nTPM]":"19.7","Tissue RNA - epididymis [nTPM]":"25.3","Tissue RNA - esophagus [nTPM]":"18.6","Tissue RNA - fallopian tube [nTPM]":"22.6","Tissue RNA - gallbladder [nTPM]":"28.6","Tissue RNA - heart muscle [nTPM]":"28.2","Tissue RNA - hippocampal formation [nTPM]":"28.0","Tissue RNA - hypothalamus [nTPM]":"28.9","Tissue RNA - kidney [nTPM]":"77.9","Tissue RNA - liver [nTPM]":"51.2","Tissue RNA - lung [nTPM]":"24.5","Tissue RNA - lymph node [nTPM]":"38.9","Tissue RNA - medulla oblongata [nTPM]":"28.2","Tissue RNA - midbrain [nTPM]":"29.5","Tissue RNA - ovary [nTPM]":"21.3","Tissue RNA - pancreas [nTPM]":"29.5","Tissue RNA - parathyroid gland [nTPM]":"25.7","Tissue RNA - pituitary gland [nTPM]":"20.3","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"28.7","Tissue RNA - prostate [nTPM]":"56.5","Tissue RNA - rectum [nTPM]":"127.4","Tissue RNA - retina [nTPM]":"18.9","Tissue RNA - salivary gland [nTPM]":"21.9","Tissue RNA - seminal vesicle [nTPM]":"21.7","Tissue RNA - skeletal muscle [nTPM]":"21.9","Tissue RNA - skin 1 [nTPM]":"21.1","Tissue RNA - small intestine [nTPM]":"183.2","Tissue RNA - smooth muscle [nTPM]":"24.6","Tissue RNA - spinal cord [nTPM]":"28.3","Tissue RNA - spleen [nTPM]":"27.9","Tissue RNA - stomach 1 [nTPM]":"26.2","Tissue RNA - testis [nTPM]":"25.3","Tissue RNA - thalamus [nTPM]":"32.1","Tissue RNA - thymus [nTPM]":"37.5","Tissue RNA - thyroid gland [nTPM]":"21.7","Tissue RNA - tongue [nTPM]":"26.3","Tissue RNA - tonsil [nTPM]":"37.7","Tissue RNA - urinary bladder [nTPM]":"27.2","Tissue RNA - vagina [nTPM]":"16.5","Tissue RNA - white matter [nTPM]":"28.3","Cell RNA - A-431 [nTPM]":"47.7","Cell RNA - A549 [nTPM]":"37.1","Cell RNA - AF22 [nTPM]":"41.5","Cell RNA - AN3-CA [nTPM]":"48.1","Cell RNA - ASC diff [nTPM]":"63.0","Cell RNA - ASC TERT1 [nTPM]":"64.0","Cell RNA - BEWO [nTPM]":"32.4","Cell RNA - BJ [nTPM]":"41.4","Cell RNA - BJ hTERT+ [nTPM]":"53.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.9","Cell RNA - CACO-2 [nTPM]":"50.8","Cell RNA - CAPAN-2 [nTPM]":"26.3","Cell RNA - Daudi [nTPM]":"57.0","Cell RNA - EFO-21 [nTPM]":"70.1","Cell RNA - fHDF\/TERT166 [nTPM]":"43.8","Cell RNA - GAMG [nTPM]":"90.0","Cell RNA - HaCaT [nTPM]":"34.2","Cell RNA - HAP1 [nTPM]":"51.2","Cell RNA - HBEC3-KT [nTPM]":"47.3","Cell RNA - HBF TERT88 [nTPM]":"52.9","Cell RNA - HDLM-2 [nTPM]":"73.6","Cell RNA - HEK 293 [nTPM]":"53.1","Cell RNA - HEL [nTPM]":"53.4","Cell RNA - HeLa [nTPM]":"37.7","Cell RNA - Hep G2 [nTPM]":"84.2","Cell RNA - HHSteC [nTPM]":"40.1","Cell RNA - HL-60 [nTPM]":"82.8","Cell RNA - HMC-1 [nTPM]":"49.5","Cell RNA - HSkMC [nTPM]":"43.1","Cell RNA - hTCEpi [nTPM]":"43.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.7","Cell RNA - hTERT-HME1 [nTPM]":"36.5","Cell RNA - hTERT-RPE1 [nTPM]":"46.0","Cell RNA - HUVEC TERT2 [nTPM]":"63.9","Cell RNA - JURKAT [nTPM]":"54.1","Cell RNA - K-562 [nTPM]":"48.8","Cell RNA - Karpas-707 [nTPM]":"23.7","Cell RNA - LHCN-M2 [nTPM]":"59.2","Cell RNA - MCF7 [nTPM]":"34.1","Cell RNA - MOLT-4 [nTPM]":"64.7","Cell RNA - NB-4 [nTPM]":"52.8","Cell RNA - NTERA-2 [nTPM]":"37.1","Cell RNA - OE19 [nTPM]":"54.7","Cell RNA - PC-3 [nTPM]":"31.8","Cell RNA - REH [nTPM]":"55.5","Cell RNA - RH-30 [nTPM]":"43.7","Cell RNA - RPMI-8226 [nTPM]":"61.6","Cell RNA - RPTEC TERT1 [nTPM]":"67.0","Cell RNA - RT4 [nTPM]":"66.5","Cell RNA - SCLC-21H [nTPM]":"52.2","Cell RNA - SH-SY5Y [nTPM]":"29.8","Cell RNA - SiHa [nTPM]":"33.6","Cell RNA - SK-BR-3 [nTPM]":"84.5","Cell RNA - SK-MEL-30 [nTPM]":"71.0","Cell RNA - SuSa [nTPM]":"42.2","Cell RNA - T-47d [nTPM]":"38.9","Cell RNA - THP-1 [nTPM]":"47.4","Cell RNA - TIME [nTPM]":"48.0","Cell RNA - U-138 MG [nTPM]":"37.6","Cell RNA - U-2 OS [nTPM]":"31.3","Cell RNA - U-2197 [nTPM]":"28.3","Cell RNA - U-251 MG [nTPM]":"61.4","Cell RNA - U-266\/70 [nTPM]":"33.7","Cell RNA - U-266\/84 [nTPM]":"107.9","Cell RNA - U-698 [nTPM]":"77.1","Cell RNA - U-87 MG [nTPM]":"26.0","Cell RNA - U-937 [nTPM]":"107.5","Cell RNA - WM-115 [nTPM]":"61.3","Blood RNA - basophil [nTPM]":"75.6","Blood RNA - classical monocyte [nTPM]":"13.9","Blood RNA - eosinophil [nTPM]":"29.4","Blood RNA - gdT-cell [nTPM]":"25.0","Blood RNA - intermediate monocyte [nTPM]":"14.8","Blood RNA - MAIT T-cell [nTPM]":"30.8","Blood RNA - memory B-cell [nTPM]":"20.0","Blood RNA - memory CD4 T-cell [nTPM]":"28.8","Blood RNA - memory CD8 T-cell [nTPM]":"27.9","Blood RNA - myeloid DC [nTPM]":"13.2","Blood RNA - naive B-cell [nTPM]":"14.5","Blood RNA - naive CD4 T-cell [nTPM]":"24.0","Blood RNA - naive CD8 T-cell [nTPM]":"26.2","Blood RNA - neutrophil [nTPM]":"228.9","Blood RNA - NK-cell [nTPM]":"29.0","Blood RNA - non-classical monocyte [nTPM]":"16.5","Blood RNA - plasmacytoid DC [nTPM]":"12.4","Blood RNA - T-reg [nTPM]":"31.9","Blood RNA - total PBMC [nTPM]":"22.7","Brain RNA - amygdala [nTPM]":"27.4","Brain RNA - basal ganglia [nTPM]":"28.4","Brain RNA - cerebellum [nTPM]":"30.4","Brain RNA - cerebral cortex [nTPM]":"36.4","Brain RNA - hippocampal formation [nTPM]":"28.0","Brain RNA - hypothalamus [nTPM]":"28.9","Brain RNA - medulla oblongata [nTPM]":"28.2","Brain RNA - midbrain [nTPM]":"29.5","Brain RNA - pons [nTPM]":"28.7","Brain RNA - spinal cord [nTPM]":"28.3","Brain RNA - thalamus [nTPM]":"32.1","Brain RNA - white matter [nTPM]":"28.3","Single Cell Type RNA - Adipocytes [nTPM]":"24.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.7","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"24.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"12.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"29.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.4","Single Cell Type RNA - dendritic cells [nTPM]":"23.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"530.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"35.4","Single Cell Type RNA - Early spermatids [nTPM]":"140.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.6","Single Cell Type RNA - Endothelial cells [nTPM]":"22.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"52.7","Single Cell Type RNA - Erythroid cells [nTPM]":"20.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.6","Single Cell Type RNA - Fibroblasts [nTPM]":"18.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.7","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"15.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.5","Single Cell Type RNA - Hepatocytes [nTPM]":"31.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"68.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"168.9","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"28.9","Single Cell Type RNA - Langerhans cells [nTPM]":"20.0","Single Cell Type RNA - Late spermatids [nTPM]":"80.2","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"33.5","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"61.7","Single Cell Type RNA - Muller glia cells [nTPM]":"19.5","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.4","Single Cell Type RNA - Paneth cells [nTPM]":"428.1","Single Cell Type RNA - Peritubular cells [nTPM]":"23.3","Single Cell Type RNA - Plasma cells [nTPM]":"10.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"637.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"175.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.4","Single Cell Type RNA - Spermatocytes [nTPM]":"9.0","Single Cell Type RNA - Spermatogonia [nTPM]":"32.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"44.3","Single Cell Type RNA - T-cells [nTPM]":"28.5","Single Cell Type RNA - Theca cells [nTPM]":"15.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"119.3","Single Cell Type RNA - Urothelial cells [nTPM]":"31.9"},{"Gene":"TDRD7","Gene synonym":["PCTAIRE2BP"],"Ensembl":"ENSG00000196116","Gene description":"Tudor domain containing 7","Uniprot":["Q8NHU6"],"Chromosome":"9","Position":"97412096-97496125","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["RNA-binding"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"63.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"44.7","Microglial cells":"33.7","Rod photoreceptor cells":"44.4","Spermatocytes":"36.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"56.5","HDLM-2":"55.6","THP-1":"54.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020800","HPA022250","HPA024529"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytoplasmic bodies"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB020800":null,"HPA022250":null,"HPA024529":"AB_1857869"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.91e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.76e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"13.6","Tissue RNA - bone marrow [nTPM]":"11.1","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"13.0","Tissue RNA - cerebral cortex [nTPM]":"12.5","Tissue RNA - cervix [nTPM]":"6.7","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"14.4","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"6.9","Tissue RNA - epididymis [nTPM]":"6.4","Tissue RNA - esophagus [nTPM]":"8.9","Tissue RNA - fallopian tube [nTPM]":"8.8","Tissue RNA - gallbladder [nTPM]":"10.2","Tissue RNA - heart muscle [nTPM]":"6.5","Tissue RNA - hippocampal formation [nTPM]":"11.0","Tissue RNA - hypothalamus [nTPM]":"13.1","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"8.1","Tissue RNA - lung [nTPM]":"9.7","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"14.2","Tissue RNA - midbrain [nTPM]":"12.3","Tissue RNA - ovary [nTPM]":"7.4","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"9.8","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"8.9","Tissue RNA - pons [nTPM]":"14.4","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"13.9","Tissue RNA - retina [nTPM]":"63.1","Tissue RNA - salivary gland [nTPM]":"7.5","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"13.7","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"14.6","Tissue RNA - spleen [nTPM]":"9.0","Tissue RNA - stomach 1 [nTPM]":"8.5","Tissue RNA - testis [nTPM]":"36.9","Tissue RNA - thalamus [nTPM]":"12.3","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"5.4","Tissue RNA - tonsil [nTPM]":"8.4","Tissue RNA - urinary bladder [nTPM]":"8.2","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"15.4","Cell RNA - A-431 [nTPM]":"17.1","Cell RNA - A549 [nTPM]":"11.7","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"4.0","Cell RNA - ASC diff [nTPM]":"8.7","Cell RNA - ASC TERT1 [nTPM]":"11.2","Cell RNA - BEWO [nTPM]":"9.8","Cell RNA - BJ [nTPM]":"10.6","Cell RNA - BJ hTERT+ [nTPM]":"26.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.9","Cell RNA - CACO-2 [nTPM]":"15.2","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"5.1","Cell RNA - fHDF\/TERT166 [nTPM]":"15.1","Cell RNA - GAMG [nTPM]":"56.5","Cell RNA - HaCaT [nTPM]":"12.8","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"5.4","Cell RNA - HBF TERT88 [nTPM]":"9.6","Cell RNA - HDLM-2 [nTPM]":"55.6","Cell RNA - HEK 293 [nTPM]":"8.3","Cell RNA - HEL [nTPM]":"7.8","Cell RNA - HeLa [nTPM]":"5.5","Cell RNA - Hep G2 [nTPM]":"11.1","Cell RNA - HHSteC [nTPM]":"7.9","Cell RNA - HL-60 [nTPM]":"17.6","Cell RNA - HMC-1 [nTPM]":"18.0","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"10.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.9","Cell RNA - hTERT-HME1 [nTPM]":"1.2","Cell RNA - hTERT-RPE1 [nTPM]":"10.7","Cell RNA - HUVEC TERT2 [nTPM]":"15.7","Cell RNA - JURKAT [nTPM]":"8.2","Cell RNA - K-562 [nTPM]":"4.4","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"9.5","Cell RNA - MCF7 [nTPM]":"10.2","Cell RNA - MOLT-4 [nTPM]":"8.8","Cell RNA - NB-4 [nTPM]":"8.6","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"20.1","Cell RNA - PC-3 [nTPM]":"6.2","Cell RNA - REH [nTPM]":"3.8","Cell RNA - RH-30 [nTPM]":"5.9","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"8.8","Cell RNA - RT4 [nTPM]":"11.4","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"4.8","Cell RNA - SiHa [nTPM]":"14.8","Cell RNA - SK-BR-3 [nTPM]":"6.5","Cell RNA - SK-MEL-30 [nTPM]":"41.6","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"3.9","Cell RNA - THP-1 [nTPM]":"54.4","Cell RNA - TIME [nTPM]":"16.1","Cell RNA - U-138 MG [nTPM]":"4.5","Cell RNA - U-2 OS [nTPM]":"4.4","Cell RNA - U-2197 [nTPM]":"11.4","Cell RNA - U-251 MG [nTPM]":"8.2","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"6.9","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"10.6","Cell RNA - U-937 [nTPM]":"9.4","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"7.2","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"4.3","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"3.2","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"4.2","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"4.2","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"13.6","Brain RNA - cerebellum [nTPM]":"13.0","Brain RNA - cerebral cortex [nTPM]":"12.5","Brain RNA - hippocampal formation [nTPM]":"11.0","Brain RNA - hypothalamus [nTPM]":"13.1","Brain RNA - medulla oblongata [nTPM]":"14.2","Brain RNA - midbrain [nTPM]":"12.3","Brain RNA - pons [nTPM]":"14.4","Brain RNA - spinal cord [nTPM]":"14.6","Brain RNA - thalamus [nTPM]":"12.3","Brain RNA - white matter [nTPM]":"15.4","Single Cell Type RNA - Adipocytes [nTPM]":"7.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"8.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.7","Single Cell Type RNA - dendritic cells [nTPM]":"3.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"44.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.2","Single Cell Type RNA - Endothelial cells [nTPM]":"6.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"23.9","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"7.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"10.8","Single Cell Type RNA - Muller glia cells [nTPM]":"8.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.1","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"4.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"36.4","Single Cell Type RNA - Spermatogonia [nTPM]":"15.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"2.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.2","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"TEAD1","Gene synonym":["AA","TCF13","TEF-1"],"Ensembl":"ENSG00000187079","Gene description":"TEA domain transcription factor 1","Uniprot":["P28347"],"Chromosome":"11","Position":"12674421-12944737","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"230.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057339","HPA062471"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA057339":"AB_2683413","HPA062471":"AB_2684773"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.5","Tissue RNA - adrenal gland [nTPM]":"12.1","Tissue RNA - amygdala [nTPM]":"11.1","Tissue RNA - appendix [nTPM]":"8.2","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"17.8","Tissue RNA - cerebellum [nTPM]":"8.6","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"23.4","Tissue RNA - choroid plexus [nTPM]":"30.6","Tissue RNA - colon [nTPM]":"36.1","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"26.4","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"29.8","Tissue RNA - fallopian tube [nTPM]":"19.2","Tissue RNA - gallbladder [nTPM]":"18.5","Tissue RNA - heart muscle [nTPM]":"31.3","Tissue RNA - hippocampal formation [nTPM]":"14.5","Tissue RNA - hypothalamus [nTPM]":"14.8","Tissue RNA - kidney [nTPM]":"17.2","Tissue RNA - liver [nTPM]":"13.6","Tissue RNA - lung [nTPM]":"15.9","Tissue RNA - lymph node [nTPM]":"4.2","Tissue RNA - medulla oblongata [nTPM]":"15.1","Tissue RNA - midbrain [nTPM]":"12.3","Tissue RNA - ovary [nTPM]":"21.9","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"27.1","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"33.3","Tissue RNA - pons [nTPM]":"10.5","Tissue RNA - prostate [nTPM]":"18.8","Tissue RNA - rectum [nTPM]":"13.0","Tissue RNA - retina [nTPM]":"10.5","Tissue RNA - salivary gland [nTPM]":"10.2","Tissue RNA - seminal vesicle [nTPM]":"20.1","Tissue RNA - skeletal muscle [nTPM]":"67.5","Tissue RNA - skin 1 [nTPM]":"13.2","Tissue RNA - small intestine [nTPM]":"11.9","Tissue RNA - smooth muscle [nTPM]":"27.2","Tissue RNA - spinal cord [nTPM]":"13.3","Tissue RNA - spleen [nTPM]":"7.3","Tissue RNA - stomach 1 [nTPM]":"16.4","Tissue RNA - testis [nTPM]":"8.6","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"17.8","Tissue RNA - tongue [nTPM]":"72.6","Tissue RNA - tonsil [nTPM]":"5.6","Tissue RNA - urinary bladder [nTPM]":"33.9","Tissue RNA - vagina [nTPM]":"14.7","Tissue RNA - white matter [nTPM]":"12.9","Cell RNA - A-431 [nTPM]":"62.8","Cell RNA - A549 [nTPM]":"52.1","Cell RNA - AF22 [nTPM]":"43.9","Cell RNA - AN3-CA [nTPM]":"58.7","Cell RNA - ASC diff [nTPM]":"59.9","Cell RNA - ASC TERT1 [nTPM]":"62.1","Cell RNA - BEWO [nTPM]":"65.4","Cell RNA - BJ [nTPM]":"89.2","Cell RNA - BJ hTERT+ [nTPM]":"76.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"71.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"69.7","Cell RNA - CACO-2 [nTPM]":"53.8","Cell RNA - CAPAN-2 [nTPM]":"54.5","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"23.0","Cell RNA - fHDF\/TERT166 [nTPM]":"120.9","Cell RNA - GAMG [nTPM]":"32.3","Cell RNA - HaCaT [nTPM]":"37.0","Cell RNA - HAP1 [nTPM]":"53.7","Cell RNA - HBEC3-KT [nTPM]":"35.9","Cell RNA - HBF TERT88 [nTPM]":"115.5","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"17.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"107.3","Cell RNA - Hep G2 [nTPM]":"18.1","Cell RNA - HHSteC [nTPM]":"55.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"4.7","Cell RNA - HSkMC [nTPM]":"51.8","Cell RNA - hTCEpi [nTPM]":"18.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.4","Cell RNA - hTERT-HME1 [nTPM]":"68.2","Cell RNA - hTERT-RPE1 [nTPM]":"58.6","Cell RNA - HUVEC TERT2 [nTPM]":"15.2","Cell RNA - JURKAT [nTPM]":"3.9","Cell RNA - K-562 [nTPM]":"26.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"111.2","Cell RNA - MCF7 [nTPM]":"13.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"17.2","Cell RNA - OE19 [nTPM]":"14.5","Cell RNA - PC-3 [nTPM]":"23.5","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"64.8","Cell RNA - RPMI-8226 [nTPM]":"33.2","Cell RNA - RPTEC TERT1 [nTPM]":"48.2","Cell RNA - RT4 [nTPM]":"37.2","Cell RNA - SCLC-21H [nTPM]":"26.9","Cell RNA - SH-SY5Y [nTPM]":"31.2","Cell RNA - SiHa [nTPM]":"90.9","Cell RNA - SK-BR-3 [nTPM]":"43.1","Cell RNA - SK-MEL-30 [nTPM]":"59.0","Cell RNA - SuSa [nTPM]":"63.8","Cell RNA - T-47d [nTPM]":"20.0","Cell RNA - THP-1 [nTPM]":"4.4","Cell RNA - TIME [nTPM]":"32.0","Cell RNA - U-138 MG [nTPM]":"107.8","Cell RNA - U-2 OS [nTPM]":"76.2","Cell RNA - U-2197 [nTPM]":"84.9","Cell RNA - U-251 MG [nTPM]":"59.5","Cell RNA - U-266\/70 [nTPM]":"8.6","Cell RNA - U-266\/84 [nTPM]":"17.3","Cell RNA - U-698 [nTPM]":"12.0","Cell RNA - U-87 MG [nTPM]":"41.6","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"69.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"11.1","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"8.6","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"14.5","Brain RNA - hypothalamus [nTPM]":"14.8","Brain RNA - medulla oblongata [nTPM]":"15.1","Brain RNA - midbrain [nTPM]":"12.3","Brain RNA - pons [nTPM]":"10.5","Brain RNA - spinal cord [nTPM]":"13.3","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"12.9","Single Cell Type RNA - Adipocytes [nTPM]":"37.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.7","Single Cell Type RNA - Astrocytes [nTPM]":"230.8","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"99.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"12.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"75.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"33.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.6","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"80.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"97.4","Single Cell Type RNA - Endothelial cells [nTPM]":"33.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"101.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"52.4","Single Cell Type RNA - Fibroblasts [nTPM]":"46.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"142.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"57.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"39.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"108.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"16.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.2","Single Cell Type RNA - Leydig cells [nTPM]":"23.6","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"91.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"31.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"121.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"69.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.8","Single Cell Type RNA - Paneth cells [nTPM]":"8.1","Single Cell Type RNA - Peritubular cells [nTPM]":"24.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"69.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"73.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"22.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.3","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"45.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"54.6"},{"Gene":"TECPR2","Gene synonym":["KIAA0329"],"Ensembl":"ENSG00000196663","Gene description":"Tectonin beta-propeller repeat containing 2","Uniprot":["O15040"],"Chromosome":"14","Position":"102362941-102502477","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"57.5","Excitatory neurons":"59.1","Oligodendrocytes":"150.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"neutrophil":"7.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"7.3"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000658"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Centrosome"],"Antibody RRID":{"HPA000658":"AB_1079191"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.66e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.53e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Tissue RNA - adipose tissue [nTPM]":"5.4","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"12.4","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"18.8","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"12.1","Tissue RNA - cerebral cortex [nTPM]":"13.9","Tissue RNA - cervix [nTPM]":"6.0","Tissue RNA - choroid plexus [nTPM]":"5.6","Tissue RNA - colon [nTPM]":"8.3","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"7.9","Tissue RNA - epididymis [nTPM]":"6.7","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"7.5","Tissue RNA - hippocampal formation [nTPM]":"12.9","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"4.1","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"13.0","Tissue RNA - midbrain [nTPM]":"14.7","Tissue RNA - ovary [nTPM]":"5.9","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"5.7","Tissue RNA - pons [nTPM]":"12.2","Tissue RNA - prostate [nTPM]":"6.4","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"9.7","Tissue RNA - salivary gland [nTPM]":"10.1","Tissue RNA - seminal vesicle [nTPM]":"7.2","Tissue RNA - skeletal muscle [nTPM]":"11.1","Tissue RNA - skin 1 [nTPM]":"5.6","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"10.4","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"10.9","Tissue RNA - thalamus [nTPM]":"15.4","Tissue RNA - thymus [nTPM]":"5.5","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"7.2","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"21.5","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"9.4","Cell RNA - AF22 [nTPM]":"8.9","Cell RNA - AN3-CA [nTPM]":"7.4","Cell RNA - ASC diff [nTPM]":"18.0","Cell RNA - ASC TERT1 [nTPM]":"13.6","Cell RNA - BEWO [nTPM]":"4.9","Cell RNA - BJ [nTPM]":"10.4","Cell RNA - BJ hTERT+ [nTPM]":"12.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.6","Cell RNA - CACO-2 [nTPM]":"2.0","Cell RNA - CAPAN-2 [nTPM]":"3.4","Cell RNA - Daudi [nTPM]":"3.5","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"10.9","Cell RNA - GAMG [nTPM]":"7.6","Cell RNA - HaCaT [nTPM]":"8.4","Cell RNA - HAP1 [nTPM]":"6.2","Cell RNA - HBEC3-KT [nTPM]":"7.8","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"13.0","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"4.2","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"8.5","Cell RNA - HL-60 [nTPM]":"2.3","Cell RNA - HMC-1 [nTPM]":"3.9","Cell RNA - HSkMC [nTPM]":"9.0","Cell RNA - hTCEpi [nTPM]":"6.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.3","Cell RNA - hTERT-HME1 [nTPM]":"6.1","Cell RNA - hTERT-RPE1 [nTPM]":"9.7","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"3.9","Cell RNA - K-562 [nTPM]":"2.1","Cell RNA - Karpas-707 [nTPM]":"7.8","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"8.9","Cell RNA - MOLT-4 [nTPM]":"2.1","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"4.9","Cell RNA - PC-3 [nTPM]":"9.7","Cell RNA - REH [nTPM]":"5.0","Cell RNA - RH-30 [nTPM]":"6.2","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"5.2","Cell RNA - RT4 [nTPM]":"7.8","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"6.6","Cell RNA - SiHa [nTPM]":"9.0","Cell RNA - SK-BR-3 [nTPM]":"2.3","Cell RNA - SK-MEL-30 [nTPM]":"5.7","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"10.5","Cell RNA - THP-1 [nTPM]":"3.1","Cell RNA - TIME [nTPM]":"10.6","Cell RNA - U-138 MG [nTPM]":"7.9","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"21.4","Cell RNA - U-251 MG [nTPM]":"4.4","Cell RNA - U-266\/70 [nTPM]":"8.0","Cell RNA - U-266\/84 [nTPM]":"5.1","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"7.6","Cell RNA - U-937 [nTPM]":"6.1","Cell RNA - WM-115 [nTPM]":"8.3","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"7.3","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"12.4","Brain RNA - basal ganglia [nTPM]":"18.8","Brain RNA - cerebellum [nTPM]":"12.1","Brain RNA - cerebral cortex [nTPM]":"13.9","Brain RNA - hippocampal formation [nTPM]":"12.9","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"13.0","Brain RNA - midbrain [nTPM]":"14.7","Brain RNA - pons [nTPM]":"12.2","Brain RNA - spinal cord [nTPM]":"10.4","Brain RNA - thalamus [nTPM]":"15.4","Brain RNA - white matter [nTPM]":"21.5","Single Cell Type RNA - Adipocytes [nTPM]":"9.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"57.5","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"17.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - dendritic cells [nTPM]":"5.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.2","Single Cell Type RNA - Early spermatids [nTPM]":"31.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"8.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"6.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.9","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.7","Single Cell Type RNA - Langerhans cells [nTPM]":"3.4","Single Cell Type RNA - Late spermatids [nTPM]":"27.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"12.7","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"8.5","Single Cell Type RNA - Muller glia cells [nTPM]":"21.6","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"150.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.8","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.3","Single Cell Type RNA - Spermatocytes [nTPM]":"24.6","Single Cell Type RNA - Spermatogonia [nTPM]":"15.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - T-cells [nTPM]":"4.6","Single Cell Type RNA - Theca cells [nTPM]":"8.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"TECTA","Gene synonym":["DFNA12","DFNA8","DFNB21"],"Ensembl":"ENSG00000109927","Gene description":"Tectorin alpha","Uniprot":["O75443"],"Chromosome":"11","Position":"121101243-121191490","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"5.2","Cone photoreceptor cells":"4.2","Early spermatids":"5.6","Excitatory neurons":"9.9","Hepatic stellate cells":"8.9","Inhibitory neurons":"7.2","Oligodendrocyte precursor cells":"5.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"1.1","SH-SY5Y":"1.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018870"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018870":"AB_1857879"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"1.1","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TENM4","Gene synonym":["KIAA1302","ODZ4","Ten-M4","TEN4"],"Ensembl":"ENSG00000149256","Gene description":"Teneurin transmembrane protein 4","Uniprot":["Q6N022"],"Chromosome":"11","Position":"78652829-79441030","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.8","ovary":"16.6","parathyroid gland":"14.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"134.5","Early spermatids":"96.8","Excitatory neurons":"337.4","Inhibitory neurons":"297.7","Microglial cells":"117.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HSkMC":"9.1","hTERT-RPE1":"9.5","PC-3":"10.8","REH":"10.4","SH-SY5Y":"17.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019521","HPA065961"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019521":"AB_2670171","HPA065961":"AB_2685588"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"7.5","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"13.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"12.6","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"9.0","Tissue RNA - hypothalamus [nTPM]":"7.5","Tissue RNA - kidney [nTPM]":"1.5","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"10.9","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"16.6","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"7.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"7.9","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"2.6","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"3.3","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"13.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"17.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.7","Cell RNA - ASC TERT1 [nTPM]":"5.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"7.8","Cell RNA - fHDF\/TERT166 [nTPM]":"6.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"2.1","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"5.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"4.5","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"9.1","Cell RNA - hTCEpi [nTPM]":"2.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.5","Cell RNA - hTERT-HME1 [nTPM]":"4.5","Cell RNA - hTERT-RPE1 [nTPM]":"9.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"10.8","Cell RNA - REH [nTPM]":"10.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.4","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"17.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"5.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"6.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.5","Brain RNA - basal ganglia [nTPM]":"13.4","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"12.6","Brain RNA - hippocampal formation [nTPM]":"9.0","Brain RNA - hypothalamus [nTPM]":"7.5","Brain RNA - medulla oblongata [nTPM]":"10.9","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"7.9","Brain RNA - spinal cord [nTPM]":"13.0","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"17.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"134.5","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"1.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"96.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"337.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"297.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"56.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"117.1","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"13.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"58.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"TFG","Gene synonym":["FLJ36137","SPG57","TF6"],"Ensembl":"ENSG00000114354","Gene description":"Trafficking from ER to golgi regulator","Uniprot":["Q92734"],"Chromosome":"3","Position":"100709295-100748964","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019473","HPA052206"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019473":"AB_1857936","HPA052206":"AB_2681760"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"62.2","Tissue RNA - adrenal gland [nTPM]":"73.0","Tissue RNA - amygdala [nTPM]":"40.7","Tissue RNA - appendix [nTPM]":"37.2","Tissue RNA - basal ganglia [nTPM]":"40.4","Tissue RNA - bone marrow [nTPM]":"37.4","Tissue RNA - breast [nTPM]":"52.4","Tissue RNA - cerebellum [nTPM]":"43.5","Tissue RNA - cerebral cortex [nTPM]":"46.4","Tissue RNA - cervix [nTPM]":"53.9","Tissue RNA - choroid plexus [nTPM]":"46.7","Tissue RNA - colon [nTPM]":"63.8","Tissue RNA - duodenum [nTPM]":"89.8","Tissue RNA - endometrium 1 [nTPM]":"52.0","Tissue RNA - epididymis [nTPM]":"78.5","Tissue RNA - esophagus [nTPM]":"85.7","Tissue RNA - fallopian tube [nTPM]":"51.2","Tissue RNA - gallbladder [nTPM]":"56.4","Tissue RNA - heart muscle [nTPM]":"82.6","Tissue RNA - hippocampal formation [nTPM]":"41.3","Tissue RNA - hypothalamus [nTPM]":"45.4","Tissue RNA - kidney [nTPM]":"71.9","Tissue RNA - liver [nTPM]":"113.9","Tissue RNA - lung [nTPM]":"55.6","Tissue RNA - lymph node [nTPM]":"29.4","Tissue RNA - medulla oblongata [nTPM]":"44.2","Tissue RNA - midbrain [nTPM]":"43.2","Tissue RNA - ovary [nTPM]":"48.2","Tissue RNA - pancreas [nTPM]":"66.7","Tissue RNA - parathyroid gland [nTPM]":"89.0","Tissue RNA - pituitary gland [nTPM]":"64.1","Tissue RNA - placenta [nTPM]":"79.2","Tissue RNA - pons [nTPM]":"44.4","Tissue RNA - prostate [nTPM]":"47.9","Tissue RNA - rectum [nTPM]":"69.6","Tissue RNA - retina [nTPM]":"40.9","Tissue RNA - salivary gland [nTPM]":"60.6","Tissue RNA - seminal vesicle [nTPM]":"61.3","Tissue RNA - skeletal muscle [nTPM]":"75.5","Tissue RNA - skin 1 [nTPM]":"58.9","Tissue RNA - small intestine [nTPM]":"76.6","Tissue RNA - smooth muscle [nTPM]":"66.5","Tissue RNA - spinal cord [nTPM]":"43.2","Tissue RNA - spleen [nTPM]":"42.6","Tissue RNA - stomach 1 [nTPM]":"54.4","Tissue RNA - testis [nTPM]":"47.7","Tissue RNA - thalamus [nTPM]":"42.3","Tissue RNA - thymus [nTPM]":"40.6","Tissue RNA - thyroid gland [nTPM]":"64.1","Tissue RNA - tongue [nTPM]":"58.2","Tissue RNA - tonsil [nTPM]":"54.9","Tissue RNA - urinary bladder [nTPM]":"61.6","Tissue RNA - vagina [nTPM]":"57.3","Tissue RNA - white matter [nTPM]":"44.4","Cell RNA - A-431 [nTPM]":"203.8","Cell RNA - A549 [nTPM]":"107.5","Cell RNA - AF22 [nTPM]":"126.7","Cell RNA - AN3-CA [nTPM]":"79.0","Cell RNA - ASC diff [nTPM]":"160.1","Cell RNA - ASC TERT1 [nTPM]":"176.4","Cell RNA - BEWO [nTPM]":"163.9","Cell RNA - BJ [nTPM]":"141.1","Cell RNA - BJ hTERT+ [nTPM]":"190.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"182.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"213.0","Cell RNA - CACO-2 [nTPM]":"136.0","Cell RNA - CAPAN-2 [nTPM]":"96.1","Cell RNA - Daudi [nTPM]":"24.7","Cell RNA - EFO-21 [nTPM]":"103.3","Cell RNA - fHDF\/TERT166 [nTPM]":"180.4","Cell RNA - GAMG [nTPM]":"141.3","Cell RNA - HaCaT [nTPM]":"143.1","Cell RNA - HAP1 [nTPM]":"143.4","Cell RNA - HBEC3-KT [nTPM]":"161.5","Cell RNA - HBF TERT88 [nTPM]":"216.2","Cell RNA - HDLM-2 [nTPM]":"123.8","Cell RNA - HEK 293 [nTPM]":"87.4","Cell RNA - HEL [nTPM]":"99.7","Cell RNA - HeLa [nTPM]":"69.3","Cell RNA - Hep G2 [nTPM]":"130.0","Cell RNA - HHSteC [nTPM]":"183.3","Cell RNA - HL-60 [nTPM]":"70.2","Cell RNA - HMC-1 [nTPM]":"51.8","Cell RNA - HSkMC [nTPM]":"149.3","Cell RNA - hTCEpi [nTPM]":"216.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"108.4","Cell RNA - hTERT-HME1 [nTPM]":"190.8","Cell RNA - hTERT-RPE1 [nTPM]":"165.1","Cell RNA - HUVEC TERT2 [nTPM]":"165.5","Cell RNA - JURKAT [nTPM]":"44.5","Cell RNA - K-562 [nTPM]":"73.1","Cell RNA - Karpas-707 [nTPM]":"63.5","Cell RNA - LHCN-M2 [nTPM]":"191.9","Cell RNA - MCF7 [nTPM]":"143.9","Cell RNA - MOLT-4 [nTPM]":"63.3","Cell RNA - NB-4 [nTPM]":"56.7","Cell RNA - NTERA-2 [nTPM]":"122.5","Cell RNA - OE19 [nTPM]":"193.8","Cell RNA - PC-3 [nTPM]":"169.3","Cell RNA - REH [nTPM]":"55.5","Cell RNA - RH-30 [nTPM]":"77.8","Cell RNA - RPMI-8226 [nTPM]":"89.0","Cell RNA - RPTEC TERT1 [nTPM]":"226.5","Cell RNA - RT4 [nTPM]":"125.9","Cell RNA - SCLC-21H [nTPM]":"96.4","Cell RNA - SH-SY5Y [nTPM]":"93.1","Cell RNA - SiHa [nTPM]":"95.0","Cell RNA - SK-BR-3 [nTPM]":"118.2","Cell RNA - SK-MEL-30 [nTPM]":"175.8","Cell RNA - SuSa [nTPM]":"103.4","Cell RNA - T-47d [nTPM]":"141.7","Cell RNA - THP-1 [nTPM]":"103.1","Cell RNA - TIME [nTPM]":"113.1","Cell RNA - U-138 MG [nTPM]":"103.0","Cell RNA - U-2 OS [nTPM]":"130.8","Cell RNA - U-2197 [nTPM]":"48.4","Cell RNA - U-251 MG [nTPM]":"104.4","Cell RNA - U-266\/70 [nTPM]":"56.2","Cell RNA - U-266\/84 [nTPM]":"65.8","Cell RNA - U-698 [nTPM]":"92.1","Cell RNA - U-87 MG [nTPM]":"171.2","Cell RNA - U-937 [nTPM]":"79.7","Cell RNA - WM-115 [nTPM]":"130.7","Blood RNA - basophil [nTPM]":"84.3","Blood RNA - classical monocyte [nTPM]":"43.6","Blood RNA - eosinophil [nTPM]":"42.8","Blood RNA - gdT-cell [nTPM]":"30.8","Blood RNA - intermediate monocyte [nTPM]":"45.2","Blood RNA - MAIT T-cell [nTPM]":"37.4","Blood RNA - memory B-cell [nTPM]":"37.4","Blood RNA - memory CD4 T-cell [nTPM]":"31.6","Blood RNA - memory CD8 T-cell [nTPM]":"34.5","Blood RNA - myeloid DC [nTPM]":"43.1","Blood RNA - naive B-cell [nTPM]":"35.9","Blood RNA - naive CD4 T-cell [nTPM]":"29.4","Blood RNA - naive CD8 T-cell [nTPM]":"29.7","Blood RNA - neutrophil [nTPM]":"26.1","Blood RNA - NK-cell [nTPM]":"43.1","Blood RNA - non-classical monocyte [nTPM]":"44.8","Blood RNA - plasmacytoid DC [nTPM]":"29.3","Blood RNA - T-reg [nTPM]":"41.0","Blood RNA - total PBMC [nTPM]":"37.0","Brain RNA - amygdala [nTPM]":"40.7","Brain RNA - basal ganglia [nTPM]":"40.4","Brain RNA - cerebellum [nTPM]":"43.5","Brain RNA - cerebral cortex [nTPM]":"46.4","Brain RNA - hippocampal formation [nTPM]":"41.3","Brain RNA - hypothalamus [nTPM]":"45.4","Brain RNA - medulla oblongata [nTPM]":"44.2","Brain RNA - midbrain [nTPM]":"43.2","Brain RNA - pons [nTPM]":"44.4","Brain RNA - spinal cord [nTPM]":"43.2","Brain RNA - thalamus [nTPM]":"42.3","Brain RNA - white matter [nTPM]":"44.4","Single Cell Type RNA - Adipocytes [nTPM]":"67.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.9","Single Cell Type RNA - Astrocytes [nTPM]":"46.4","Single Cell Type RNA - B-cells [nTPM]":"43.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"136.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"105.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"183.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"69.4","Single Cell Type RNA - Bipolar cells [nTPM]":"46.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"83.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"93.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"211.6","Single Cell Type RNA - dendritic cells [nTPM]":"43.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"111.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"137.0","Single Cell Type RNA - Ductal cells [nTPM]":"190.3","Single Cell Type RNA - Early spermatids [nTPM]":"101.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"70.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"70.4","Single Cell Type RNA - Endothelial cells [nTPM]":"70.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"52.6","Single Cell Type RNA - Erythroid cells [nTPM]":"27.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"54.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"107.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"201.5","Single Cell Type RNA - Fibroblasts [nTPM]":"97.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"47.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"79.0","Single Cell Type RNA - granulocytes [nTPM]":"76.8","Single Cell Type RNA - Granulosa cells [nTPM]":"62.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.9","Single Cell Type RNA - Hepatocytes [nTPM]":"68.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"86.2","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"128.5","Single Cell Type RNA - Ionocytes [nTPM]":"122.1","Single Cell Type RNA - Kupffer cells [nTPM]":"27.3","Single Cell Type RNA - Langerhans cells [nTPM]":"84.9","Single Cell Type RNA - Late spermatids [nTPM]":"45.5","Single Cell Type RNA - Leydig cells [nTPM]":"70.8","Single Cell Type RNA - Macrophages [nTPM]":"43.6","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"98.5","Single Cell Type RNA - Muller glia cells [nTPM]":"88.0","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"55.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"130.5","Single Cell Type RNA - Paneth cells [nTPM]":"91.0","Single Cell Type RNA - Peritubular cells [nTPM]":"74.1","Single Cell Type RNA - Plasma cells [nTPM]":"75.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"133.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"202.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"106.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"63.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"60.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"81.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"87.2","Single Cell Type RNA - Spermatocytes [nTPM]":"79.2","Single Cell Type RNA - Spermatogonia [nTPM]":"51.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"68.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"118.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"284.4","Single Cell Type RNA - T-cells [nTPM]":"43.2","Single Cell Type RNA - Theca cells [nTPM]":"90.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"97.2","Single Cell Type RNA - Urothelial cells [nTPM]":"123.0"},{"Gene":"TGFBI","Gene synonym":["BIGH3","CDB1","CDGG1","CSD1","CSD2","CSD3","LCD1"],"Ensembl":"ENSG00000120708","Gene description":"Transforming growth factor beta induced","Uniprot":["Q15582"],"Chromosome":"5","Position":"136028988-136063818","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Amyloidosis","Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"457.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"251.8","Kupffer cells":"292.9","Langerhans cells":"251.2","Macrophages":"198.9","Pancreatic endocrine cells":"590.1","Smooth muscle cells":"326.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"77.3"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"32","RNA blood cell specific nTPM":{"classical monocyte":"252.3","intermediate monocyte":"149.1","myeloid DC":"156.9","non-classical monocyte":"121.4","plasmacytoid DC":"324.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"46","RNA blood lineage specific nTPM":{"dendritic cells":"324.5","monocytes":"252.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"2857.3","GAMG":"2417.8","HSkMC":"2675.6","hTCEpi":"1915.6","LHCN-M2":"2269.4","U-2197":"1916.3","U-87 MG":"3667.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008612","HPA017019"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008612":"AB_1857970","HPA017019":"AB_2669511"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.82e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-3"},"Tissue RNA - adipose tissue [nTPM]":"133.2","Tissue RNA - adrenal gland [nTPM]":"55.3","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"164.0","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"25.9","Tissue RNA - breast [nTPM]":"112.2","Tissue RNA - cerebellum [nTPM]":"10.0","Tissue RNA - cerebral cortex [nTPM]":"25.5","Tissue RNA - cervix [nTPM]":"51.8","Tissue RNA - choroid plexus [nTPM]":"51.9","Tissue RNA - colon [nTPM]":"92.8","Tissue RNA - duodenum [nTPM]":"48.2","Tissue RNA - endometrium 1 [nTPM]":"59.7","Tissue RNA - epididymis [nTPM]":"41.6","Tissue RNA - esophagus [nTPM]":"28.7","Tissue RNA - fallopian tube [nTPM]":"59.7","Tissue RNA - gallbladder [nTPM]":"146.1","Tissue RNA - heart muscle [nTPM]":"95.5","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"124.0","Tissue RNA - liver [nTPM]":"132.1","Tissue RNA - lung [nTPM]":"89.7","Tissue RNA - lymph node [nTPM]":"66.2","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"25.4","Tissue RNA - pancreas [nTPM]":"22.4","Tissue RNA - parathyroid gland [nTPM]":"18.4","Tissue RNA - pituitary gland [nTPM]":"77.6","Tissue RNA - placenta [nTPM]":"457.6","Tissue RNA - pons [nTPM]":"15.7","Tissue RNA - prostate [nTPM]":"69.5","Tissue RNA - rectum [nTPM]":"84.4","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"68.3","Tissue RNA - seminal vesicle [nTPM]":"58.9","Tissue RNA - skeletal muscle [nTPM]":"34.8","Tissue RNA - skin 1 [nTPM]":"314.1","Tissue RNA - small intestine [nTPM]":"65.3","Tissue RNA - smooth muscle [nTPM]":"291.0","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"121.1","Tissue RNA - stomach 1 [nTPM]":"67.4","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"77.3","Tissue RNA - thymus [nTPM]":"57.7","Tissue RNA - thyroid gland [nTPM]":"40.4","Tissue RNA - tongue [nTPM]":"41.7","Tissue RNA - tonsil [nTPM]":"44.4","Tissue RNA - urinary bladder [nTPM]":"138.9","Tissue RNA - vagina [nTPM]":"39.0","Tissue RNA - white matter [nTPM]":"14.0","Cell RNA - A-431 [nTPM]":"102.2","Cell RNA - A549 [nTPM]":"405.6","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"3.8","Cell RNA - ASC diff [nTPM]":"1104.3","Cell RNA - ASC TERT1 [nTPM]":"354.4","Cell RNA - BEWO [nTPM]":"1.5","Cell RNA - BJ [nTPM]":"295.1","Cell RNA - BJ hTERT+ [nTPM]":"42.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"209.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"125.1","Cell RNA - CACO-2 [nTPM]":"186.4","Cell RNA - CAPAN-2 [nTPM]":"1276.3","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"181.6","Cell RNA - fHDF\/TERT166 [nTPM]":"2857.3","Cell RNA - GAMG [nTPM]":"2417.8","Cell RNA - HaCaT [nTPM]":"498.0","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"981.4","Cell RNA - HBF TERT88 [nTPM]":"208.0","Cell RNA - HDLM-2 [nTPM]":"2.3","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"451.6","Cell RNA - Hep G2 [nTPM]":"501.3","Cell RNA - HHSteC [nTPM]":"718.9","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"3.9","Cell RNA - HSkMC [nTPM]":"2675.6","Cell RNA - hTCEpi [nTPM]":"1915.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"77.9","Cell RNA - hTERT-HME1 [nTPM]":"93.1","Cell RNA - hTERT-RPE1 [nTPM]":"827.5","Cell RNA - HUVEC TERT2 [nTPM]":"188.1","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"3.8","Cell RNA - LHCN-M2 [nTPM]":"2269.4","Cell RNA - MCF7 [nTPM]":"4.8","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"13.1","Cell RNA - OE19 [nTPM]":"5.1","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"24.3","Cell RNA - RPMI-8226 [nTPM]":"3.4","Cell RNA - RPTEC TERT1 [nTPM]":"96.7","Cell RNA - RT4 [nTPM]":"8.8","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"473.7","Cell RNA - SK-BR-3 [nTPM]":"15.5","Cell RNA - SK-MEL-30 [nTPM]":"3.9","Cell RNA - SuSa [nTPM]":"452.8","Cell RNA - T-47d [nTPM]":"3.7","Cell RNA - THP-1 [nTPM]":"110.9","Cell RNA - TIME [nTPM]":"745.6","Cell RNA - U-138 MG [nTPM]":"1419.3","Cell RNA - U-2 OS [nTPM]":"59.8","Cell RNA - U-2197 [nTPM]":"1916.3","Cell RNA - U-251 MG [nTPM]":"1139.6","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"3667.3","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"1077.5","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"252.3","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"149.1","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"156.9","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"5.3","Blood RNA - NK-cell [nTPM]":"6.2","Blood RNA - non-classical monocyte [nTPM]":"121.4","Blood RNA - plasmacytoid DC [nTPM]":"324.5","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"108.5","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"10.0","Brain RNA - cerebral cortex [nTPM]":"25.5","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"15.7","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"77.3","Brain RNA - white matter [nTPM]":"14.0","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"119.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"141.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"21.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - dendritic cells [nTPM]":"146.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"67.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"57.9","Single Cell Type RNA - Endothelial cells [nTPM]":"16.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"112.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.5","Single Cell Type RNA - Fibroblasts [nTPM]":"113.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"25.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"251.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"292.9","Single Cell Type RNA - Langerhans cells [nTPM]":"251.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"198.9","Single Cell Type RNA - Melanocytes [nTPM]":"49.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"151.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"590.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"156.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"326.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"55.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - T-cells [nTPM]":"8.5","Single Cell Type RNA - Theca cells [nTPM]":"10.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"2.5"},{"Gene":"TGM6","Gene synonym":["dJ734P14.3","SCA35","TGM3L","TGY"],"Ensembl":"ENSG00000166948","Gene description":"Transglutaminase 6","Uniprot":["O95932"],"Chromosome":"20","Position":"2380901-2432753","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"10","RNA pig brain regional specific nTPM":{"cerebellum":"1.0"},"Antibody":["HPA059196"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059196":"AB_2683943"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TH","Gene synonym":["DYT5b"],"Ensembl":"ENSG00000180176","Gene description":"Tyrosine hydroxylase","Uniprot":["P07101"],"Chromosome":"11","Position":"2163929-2171815","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Catecholamine biosynthesis","Neurotransmitter biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Dystonia","FDA approved drug targets","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"69","RNA tissue specific nTPM":{"adrenal gland":"196.6","brain":"270.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"9.0","Extravillous trophoblasts":"12.4","Leydig cells":"3.4","Syncytiotrophoblasts":"2.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"urothelial cancer":"4.0"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"midbrain":"192.4","pons":"270.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"30","RNA cell line specific nTPM":{"PC-3":"60.8","SK-BR-3":"21.0"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"178.8"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"20","RNA pig brain regional specific nTPM":{"midbrain":"594.4"},"Antibody":["CAB002522","HPA013768","HPA014010","HPA061003","CAB072340"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002522":"AB_564047","CAB072340":null,"HPA013768":null,"HPA014010":null,"HPA061003":"AB_2630374"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"196.6","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"46.5","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"13.9","Tissue RNA - midbrain [nTPM]":"192.4","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"270.9","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"14.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"60.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"21.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"46.5","Brain RNA - medulla oblongata [nTPM]":"13.9","Brain RNA - midbrain [nTPM]":"192.4","Brain RNA - pons [nTPM]":"270.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"14.6","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"THAP1","Gene synonym":["4833431A01Rik","DYT6","FLJ10477"],"Ensembl":"ENSG00000131931","Gene description":"THAP domain containing 1","Uniprot":["Q9NVV9"],"Chromosome":"8","Position":"42836674-42843325","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Cell cycle","Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071310"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA071310":"AB_2686386"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"5.1","Tissue RNA - bone marrow [nTPM]":"8.3","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"6.2","Tissue RNA - choroid plexus [nTPM]":"4.9","Tissue RNA - colon [nTPM]":"6.2","Tissue RNA - duodenum [nTPM]":"5.9","Tissue RNA - endometrium 1 [nTPM]":"6.9","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"8.8","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"8.7","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"9.5","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"5.7","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"12.4","Tissue RNA - skin 1 [nTPM]":"4.0","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"6.8","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"9.4","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"11.5","Tissue RNA - thyroid gland [nTPM]":"8.6","Tissue RNA - tongue [nTPM]":"12.5","Tissue RNA - tonsil [nTPM]":"8.4","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"10.5","Cell RNA - A549 [nTPM]":"9.3","Cell RNA - AF22 [nTPM]":"8.5","Cell RNA - AN3-CA [nTPM]":"8.2","Cell RNA - ASC diff [nTPM]":"12.7","Cell RNA - ASC TERT1 [nTPM]":"14.3","Cell RNA - BEWO [nTPM]":"10.2","Cell RNA - BJ [nTPM]":"14.2","Cell RNA - BJ hTERT+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.7","Cell RNA - CACO-2 [nTPM]":"8.0","Cell RNA - CAPAN-2 [nTPM]":"13.2","Cell RNA - Daudi [nTPM]":"12.8","Cell RNA - EFO-21 [nTPM]":"11.3","Cell RNA - fHDF\/TERT166 [nTPM]":"10.5","Cell RNA - GAMG [nTPM]":"19.0","Cell RNA - HaCaT [nTPM]":"10.7","Cell RNA - HAP1 [nTPM]":"14.0","Cell RNA - HBEC3-KT [nTPM]":"12.0","Cell RNA - HBF TERT88 [nTPM]":"16.2","Cell RNA - HDLM-2 [nTPM]":"12.4","Cell RNA - HEK 293 [nTPM]":"10.3","Cell RNA - HEL [nTPM]":"12.5","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"9.4","Cell RNA - HHSteC [nTPM]":"15.6","Cell RNA - HL-60 [nTPM]":"10.4","Cell RNA - HMC-1 [nTPM]":"12.7","Cell RNA - HSkMC [nTPM]":"11.3","Cell RNA - hTCEpi [nTPM]":"17.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.1","Cell RNA - hTERT-HME1 [nTPM]":"18.2","Cell RNA - hTERT-RPE1 [nTPM]":"12.4","Cell RNA - HUVEC TERT2 [nTPM]":"16.5","Cell RNA - JURKAT [nTPM]":"17.1","Cell RNA - K-562 [nTPM]":"14.1","Cell RNA - Karpas-707 [nTPM]":"14.7","Cell RNA - LHCN-M2 [nTPM]":"15.1","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"25.1","Cell RNA - NB-4 [nTPM]":"12.1","Cell RNA - NTERA-2 [nTPM]":"16.8","Cell RNA - OE19 [nTPM]":"16.9","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"11.2","Cell RNA - RH-30 [nTPM]":"15.2","Cell RNA - RPMI-8226 [nTPM]":"10.2","Cell RNA - RPTEC TERT1 [nTPM]":"13.9","Cell RNA - RT4 [nTPM]":"7.8","Cell RNA - SCLC-21H [nTPM]":"6.9","Cell RNA - SH-SY5Y [nTPM]":"8.1","Cell RNA - SiHa [nTPM]":"15.5","Cell RNA - SK-BR-3 [nTPM]":"9.7","Cell RNA - SK-MEL-30 [nTPM]":"20.2","Cell RNA - SuSa [nTPM]":"11.2","Cell RNA - T-47d [nTPM]":"13.5","Cell RNA - THP-1 [nTPM]":"11.6","Cell RNA - TIME [nTPM]":"10.0","Cell RNA - U-138 MG [nTPM]":"11.2","Cell RNA - U-2 OS [nTPM]":"8.3","Cell RNA - U-2197 [nTPM]":"15.0","Cell RNA - U-251 MG [nTPM]":"14.3","Cell RNA - U-266\/70 [nTPM]":"11.9","Cell RNA - U-266\/84 [nTPM]":"14.0","Cell RNA - U-698 [nTPM]":"12.2","Cell RNA - U-87 MG [nTPM]":"11.2","Cell RNA - U-937 [nTPM]":"13.6","Cell RNA - WM-115 [nTPM]":"12.4","Blood RNA - basophil [nTPM]":"23.8","Blood RNA - classical monocyte [nTPM]":"18.6","Blood RNA - eosinophil [nTPM]":"30.8","Blood RNA - gdT-cell [nTPM]":"19.9","Blood RNA - intermediate monocyte [nTPM]":"16.7","Blood RNA - MAIT T-cell [nTPM]":"21.6","Blood RNA - memory B-cell [nTPM]":"20.4","Blood RNA - memory CD4 T-cell [nTPM]":"23.1","Blood RNA - memory CD8 T-cell [nTPM]":"22.1","Blood RNA - myeloid DC [nTPM]":"19.9","Blood RNA - naive B-cell [nTPM]":"17.8","Blood RNA - naive CD4 T-cell [nTPM]":"26.9","Blood RNA - naive CD8 T-cell [nTPM]":"21.5","Blood RNA - neutrophil [nTPM]":"22.0","Blood RNA - NK-cell [nTPM]":"19.3","Blood RNA - non-classical monocyte [nTPM]":"18.0","Blood RNA - plasmacytoid DC [nTPM]":"9.8","Blood RNA - T-reg [nTPM]":"32.5","Blood RNA - total PBMC [nTPM]":"18.8","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"5.1","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"17.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.4","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"20.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"10.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.5","Single Cell Type RNA - dendritic cells [nTPM]":"17.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"17.5","Single Cell Type RNA - Early spermatids [nTPM]":"35.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.2","Single Cell Type RNA - Endothelial cells [nTPM]":"15.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.3","Single Cell Type RNA - Erythroid cells [nTPM]":"18.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.8","Single Cell Type RNA - Fibroblasts [nTPM]":"14.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"12.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.2","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.8","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"11.6","Single Cell Type RNA - Langerhans cells [nTPM]":"9.2","Single Cell Type RNA - Late spermatids [nTPM]":"17.9","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"13.4","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"20.2","Single Cell Type RNA - Muller glia cells [nTPM]":"15.6","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.6","Single Cell Type RNA - Paneth cells [nTPM]":"4.0","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"18.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.0","Single Cell Type RNA - Spermatocytes [nTPM]":"32.6","Single Cell Type RNA - Spermatogonia [nTPM]":"45.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - T-cells [nTPM]":"24.6","Single Cell Type RNA - Theca cells [nTPM]":"12.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.6","Single Cell Type RNA - Urothelial cells [nTPM]":"8.2"},{"Gene":"THG1L","Gene synonym":["FLJ11601","FLJ20546","hTHG1","ICF45","IHG-1"],"Ensembl":"ENSG00000113272","Gene description":"TRNA-histidine guanylyltransferase 1 like","Uniprot":["Q9NWX6"],"Chromosome":"5","Position":"157731420-157741449","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035877","HPA035878"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035877":"AB_10669979","HPA035878":"AB_10672993"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.93e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.8","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"5.9","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"5.1","Tissue RNA - lung [nTPM]":"3.0","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.4","Tissue RNA - ovary [nTPM]":"7.6","Tissue RNA - pancreas [nTPM]":"4.7","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"7.7","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"4.1","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"4.9","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"6.7","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"6.0","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"4.6","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"8.8","Cell RNA - A549 [nTPM]":"15.4","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"13.8","Cell RNA - ASC diff [nTPM]":"6.7","Cell RNA - ASC TERT1 [nTPM]":"19.6","Cell RNA - BEWO [nTPM]":"5.5","Cell RNA - BJ [nTPM]":"6.8","Cell RNA - BJ hTERT+ [nTPM]":"12.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.1","Cell RNA - CACO-2 [nTPM]":"21.4","Cell RNA - CAPAN-2 [nTPM]":"8.7","Cell RNA - Daudi [nTPM]":"21.8","Cell RNA - EFO-21 [nTPM]":"5.7","Cell RNA - fHDF\/TERT166 [nTPM]":"6.0","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"9.1","Cell RNA - HAP1 [nTPM]":"9.0","Cell RNA - HBEC3-KT [nTPM]":"13.1","Cell RNA - HBF TERT88 [nTPM]":"15.2","Cell RNA - HDLM-2 [nTPM]":"8.9","Cell RNA - HEK 293 [nTPM]":"12.0","Cell RNA - HEL [nTPM]":"7.7","Cell RNA - HeLa [nTPM]":"10.2","Cell RNA - Hep G2 [nTPM]":"9.1","Cell RNA - HHSteC [nTPM]":"7.6","Cell RNA - HL-60 [nTPM]":"16.6","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"17.8","Cell RNA - hTCEpi [nTPM]":"15.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.1","Cell RNA - hTERT-HME1 [nTPM]":"16.6","Cell RNA - hTERT-RPE1 [nTPM]":"13.0","Cell RNA - HUVEC TERT2 [nTPM]":"5.1","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"13.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"8.2","Cell RNA - MCF7 [nTPM]":"12.1","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"11.3","Cell RNA - NTERA-2 [nTPM]":"6.9","Cell RNA - OE19 [nTPM]":"3.9","Cell RNA - PC-3 [nTPM]":"14.8","Cell RNA - REH [nTPM]":"3.3","Cell RNA - RH-30 [nTPM]":"13.8","Cell RNA - RPMI-8226 [nTPM]":"12.6","Cell RNA - RPTEC TERT1 [nTPM]":"8.5","Cell RNA - RT4 [nTPM]":"11.0","Cell RNA - SCLC-21H [nTPM]":"9.1","Cell RNA - SH-SY5Y [nTPM]":"12.8","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"8.2","Cell RNA - SK-MEL-30 [nTPM]":"11.3","Cell RNA - SuSa [nTPM]":"5.2","Cell RNA - T-47d [nTPM]":"13.9","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"10.9","Cell RNA - U-2 OS [nTPM]":"7.2","Cell RNA - U-2197 [nTPM]":"9.2","Cell RNA - U-251 MG [nTPM]":"18.5","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"7.1","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"15.9","Cell RNA - WM-115 [nTPM]":"6.9","Blood RNA - basophil [nTPM]":"3.9","Blood RNA - classical monocyte [nTPM]":"7.8","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"8.7","Blood RNA - MAIT T-cell [nTPM]":"3.9","Blood RNA - memory B-cell [nTPM]":"5.7","Blood RNA - memory CD4 T-cell [nTPM]":"4.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"7.0","Blood RNA - naive B-cell [nTPM]":"4.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.3","Blood RNA - naive CD8 T-cell [nTPM]":"5.3","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"6.7","Blood RNA - non-classical monocyte [nTPM]":"8.7","Blood RNA - plasmacytoid DC [nTPM]":"4.5","Blood RNA - T-reg [nTPM]":"5.0","Blood RNA - total PBMC [nTPM]":"3.9","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.4","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"14.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"11.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.6","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"17.1","Single Cell Type RNA - Early spermatids [nTPM]":"19.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.8","Single Cell Type RNA - Endothelial cells [nTPM]":"9.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"23.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.8","Single Cell Type RNA - Fibroblasts [nTPM]":"15.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"17.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"8.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"17.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"16.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"21.2","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.1","Single Cell Type RNA - Paneth cells [nTPM]":"19.6","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.4","Single Cell Type RNA - Spermatocytes [nTPM]":"19.8","Single Cell Type RNA - Spermatogonia [nTPM]":"8.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - T-cells [nTPM]":"11.2","Single Cell Type RNA - Theca cells [nTPM]":"38.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.1","Single Cell Type RNA - Urothelial cells [nTPM]":"28.4"},{"Gene":"TIMM8A","Gene synonym":["DDP","DFN1","MTS"],"Ensembl":"ENSG00000126953","Gene description":"Translocase of inner mitochondrial membrane 8A","Uniprot":["O60220"],"Chromosome":"X","Position":"101345661-101348742","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":["Chaperone"],"Disease involvement":["Deafness","Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"102.2","Hepatocytes":"68.3","Suprabasal keratinocytes":"88.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"217.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003628"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"59000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA003628":"AB_1080284"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.89e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.87e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.1","Tissue RNA - adrenal gland [nTPM]":"5.6","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"6.5","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"6.9","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"4.4","Tissue RNA - choroid plexus [nTPM]":"4.8","Tissue RNA - colon [nTPM]":"7.2","Tissue RNA - duodenum [nTPM]":"6.6","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"7.0","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"10.9","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"9.2","Tissue RNA - liver [nTPM]":"25.3","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"8.2","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"5.5","Tissue RNA - ovary [nTPM]":"5.9","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"6.5","Tissue RNA - rectum [nTPM]":"7.5","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"3.7","Tissue RNA - skeletal muscle [nTPM]":"10.0","Tissue RNA - skin 1 [nTPM]":"6.5","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"5.0","Tissue RNA - spleen [nTPM]":"4.5","Tissue RNA - stomach 1 [nTPM]":"4.2","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"6.5","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"3.1","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"31.5","Cell RNA - A549 [nTPM]":"30.0","Cell RNA - AF22 [nTPM]":"17.1","Cell RNA - AN3-CA [nTPM]":"33.8","Cell RNA - ASC diff [nTPM]":"13.3","Cell RNA - ASC TERT1 [nTPM]":"15.0","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"23.5","Cell RNA - BJ hTERT+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.6","Cell RNA - CACO-2 [nTPM]":"26.4","Cell RNA - CAPAN-2 [nTPM]":"21.3","Cell RNA - Daudi [nTPM]":"38.0","Cell RNA - EFO-21 [nTPM]":"29.7","Cell RNA - fHDF\/TERT166 [nTPM]":"17.8","Cell RNA - GAMG [nTPM]":"36.5","Cell RNA - HaCaT [nTPM]":"27.7","Cell RNA - HAP1 [nTPM]":"46.2","Cell RNA - HBEC3-KT [nTPM]":"24.5","Cell RNA - HBF TERT88 [nTPM]":"33.3","Cell RNA - HDLM-2 [nTPM]":"17.7","Cell RNA - HEK 293 [nTPM]":"29.9","Cell RNA - HEL [nTPM]":"62.8","Cell RNA - HeLa [nTPM]":"44.7","Cell RNA - Hep G2 [nTPM]":"46.5","Cell RNA - HHSteC [nTPM]":"12.7","Cell RNA - HL-60 [nTPM]":"39.9","Cell RNA - HMC-1 [nTPM]":"217.8","Cell RNA - HSkMC [nTPM]":"15.0","Cell RNA - hTCEpi [nTPM]":"21.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.0","Cell RNA - hTERT-HME1 [nTPM]":"18.8","Cell RNA - hTERT-RPE1 [nTPM]":"9.6","Cell RNA - HUVEC TERT2 [nTPM]":"19.7","Cell RNA - JURKAT [nTPM]":"15.9","Cell RNA - K-562 [nTPM]":"51.0","Cell RNA - Karpas-707 [nTPM]":"40.8","Cell RNA - LHCN-M2 [nTPM]":"26.8","Cell RNA - MCF7 [nTPM]":"50.7","Cell RNA - MOLT-4 [nTPM]":"18.3","Cell RNA - NB-4 [nTPM]":"39.1","Cell RNA - NTERA-2 [nTPM]":"55.3","Cell RNA - OE19 [nTPM]":"46.4","Cell RNA - PC-3 [nTPM]":"49.3","Cell RNA - REH [nTPM]":"30.2","Cell RNA - RH-30 [nTPM]":"31.1","Cell RNA - RPMI-8226 [nTPM]":"44.9","Cell RNA - RPTEC TERT1 [nTPM]":"18.3","Cell RNA - RT4 [nTPM]":"21.1","Cell RNA - SCLC-21H [nTPM]":"22.7","Cell RNA - SH-SY5Y [nTPM]":"20.9","Cell RNA - SiHa [nTPM]":"28.6","Cell RNA - SK-BR-3 [nTPM]":"22.8","Cell RNA - SK-MEL-30 [nTPM]":"22.5","Cell RNA - SuSa [nTPM]":"18.8","Cell RNA - T-47d [nTPM]":"19.1","Cell RNA - THP-1 [nTPM]":"19.3","Cell RNA - TIME [nTPM]":"14.2","Cell RNA - U-138 MG [nTPM]":"27.5","Cell RNA - U-2 OS [nTPM]":"31.5","Cell RNA - U-2197 [nTPM]":"40.6","Cell RNA - U-251 MG [nTPM]":"26.1","Cell RNA - U-266\/70 [nTPM]":"18.7","Cell RNA - U-266\/84 [nTPM]":"50.8","Cell RNA - U-698 [nTPM]":"45.9","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"53.8","Cell RNA - WM-115 [nTPM]":"22.2","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"4.9","Blood RNA - intermediate monocyte [nTPM]":"5.8","Blood RNA - MAIT T-cell [nTPM]":"7.0","Blood RNA - memory B-cell [nTPM]":"12.1","Blood RNA - memory CD4 T-cell [nTPM]":"6.8","Blood RNA - memory CD8 T-cell [nTPM]":"7.2","Blood RNA - myeloid DC [nTPM]":"4.6","Blood RNA - naive B-cell [nTPM]":"11.9","Blood RNA - naive CD4 T-cell [nTPM]":"10.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.4","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"5.2","Blood RNA - non-classical monocyte [nTPM]":"3.1","Blood RNA - plasmacytoid DC [nTPM]":"11.7","Blood RNA - T-reg [nTPM]":"3.8","Blood RNA - total PBMC [nTPM]":"4.3","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"5.5","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"5.0","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"7.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"10.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"102.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"39.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"7.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"14.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.4","Single Cell Type RNA - dendritic cells [nTPM]":"8.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"13.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.8","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"27.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.6","Single Cell Type RNA - Fibroblasts [nTPM]":"13.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.3","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"9.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"68.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"13.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"7.5","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"5.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.4","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.7","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"13.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"10.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"88.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.7","Single Cell Type RNA - T-cells [nTPM]":"6.9","Single Cell Type RNA - Theca cells [nTPM]":"12.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.0","Single Cell Type RNA - Urothelial cells [nTPM]":"27.8"},{"Gene":"TIMP3","Gene synonym":["SFD"],"Ensembl":"ENSG00000100234","Gene description":"TIMP metallopeptidase inhibitor 3","Uniprot":["P35625"],"Chromosome":"22","Position":"32801705-32863041","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Metalloenzyme inhibitor","Metalloprotease inhibitor","Protease inhibitor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"1663.5","Fibroblasts":"967.5","Leydig cells":"1398.6","Peritubular cells":"1934.1","Sertoli cells":"2327.1","Smooth muscle cells":"1116.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"502.6","BJ":"1173.0","BJ hTERT+":"514.7","fHDF\/TERT166":"1073.7","WM-115":"893.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068391"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA068391":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"805.5","Tissue RNA - adrenal gland [nTPM]":"288.7","Tissue RNA - amygdala [nTPM]":"71.7","Tissue RNA - appendix [nTPM]":"41.4","Tissue RNA - basal ganglia [nTPM]":"74.9","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"556.9","Tissue RNA - cerebellum [nTPM]":"68.7","Tissue RNA - cerebral cortex [nTPM]":"72.6","Tissue RNA - cervix [nTPM]":"376.1","Tissue RNA - choroid plexus [nTPM]":"221.0","Tissue RNA - colon [nTPM]":"190.4","Tissue RNA - duodenum [nTPM]":"30.5","Tissue RNA - endometrium 1 [nTPM]":"393.3","Tissue RNA - epididymis [nTPM]":"230.4","Tissue RNA - esophagus [nTPM]":"168.1","Tissue RNA - fallopian tube [nTPM]":"373.9","Tissue RNA - gallbladder [nTPM]":"153.5","Tissue RNA - heart muscle [nTPM]":"532.8","Tissue RNA - hippocampal formation [nTPM]":"64.3","Tissue RNA - hypothalamus [nTPM]":"79.2","Tissue RNA - kidney [nTPM]":"248.0","Tissue RNA - liver [nTPM]":"92.0","Tissue RNA - lung [nTPM]":"625.1","Tissue RNA - lymph node [nTPM]":"69.5","Tissue RNA - medulla oblongata [nTPM]":"83.2","Tissue RNA - midbrain [nTPM]":"86.7","Tissue RNA - ovary [nTPM]":"116.2","Tissue RNA - pancreas [nTPM]":"81.1","Tissue RNA - parathyroid gland [nTPM]":"139.5","Tissue RNA - pituitary gland [nTPM]":"139.1","Tissue RNA - placenta [nTPM]":"999.5","Tissue RNA - pons [nTPM]":"76.0","Tissue RNA - prostate [nTPM]":"178.8","Tissue RNA - rectum [nTPM]":"81.2","Tissue RNA - retina [nTPM]":"31.7","Tissue RNA - salivary gland [nTPM]":"178.7","Tissue RNA - seminal vesicle [nTPM]":"341.1","Tissue RNA - skeletal muscle [nTPM]":"128.1","Tissue RNA - skin 1 [nTPM]":"170.3","Tissue RNA - small intestine [nTPM]":"122.1","Tissue RNA - smooth muscle [nTPM]":"379.6","Tissue RNA - spinal cord [nTPM]":"70.3","Tissue RNA - spleen [nTPM]":"187.2","Tissue RNA - stomach 1 [nTPM]":"152.1","Tissue RNA - testis [nTPM]":"64.1","Tissue RNA - thalamus [nTPM]":"106.2","Tissue RNA - thymus [nTPM]":"41.1","Tissue RNA - thyroid gland [nTPM]":"340.1","Tissue RNA - tongue [nTPM]":"325.9","Tissue RNA - tonsil [nTPM]":"28.8","Tissue RNA - urinary bladder [nTPM]":"197.4","Tissue RNA - vagina [nTPM]":"261.1","Tissue RNA - white matter [nTPM]":"59.5","Cell RNA - A-431 [nTPM]":"19.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"16.9","Cell RNA - AN3-CA [nTPM]":"2.7","Cell RNA - ASC diff [nTPM]":"502.6","Cell RNA - ASC TERT1 [nTPM]":"280.6","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"1173.0","Cell RNA - BJ hTERT+ [nTPM]":"514.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"94.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"110.8","Cell RNA - CACO-2 [nTPM]":"20.5","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"28.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1073.7","Cell RNA - GAMG [nTPM]":"3.6","Cell RNA - HaCaT [nTPM]":"18.3","Cell RNA - HAP1 [nTPM]":"3.2","Cell RNA - HBEC3-KT [nTPM]":"48.4","Cell RNA - HBF TERT88 [nTPM]":"135.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"14.3","Cell RNA - HEL [nTPM]":"147.4","Cell RNA - HeLa [nTPM]":"23.5","Cell RNA - Hep G2 [nTPM]":"52.4","Cell RNA - HHSteC [nTPM]":"197.4","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"59.7","Cell RNA - HSkMC [nTPM]":"47.4","Cell RNA - hTCEpi [nTPM]":"120.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"166.9","Cell RNA - hTERT-HME1 [nTPM]":"9.5","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"44.6","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"5.0","Cell RNA - NTERA-2 [nTPM]":"2.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"3.4","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"97.0","Cell RNA - SCLC-21H [nTPM]":"12.5","Cell RNA - SH-SY5Y [nTPM]":"16.8","Cell RNA - SiHa [nTPM]":"24.1","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"322.9","Cell RNA - SuSa [nTPM]":"266.6","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"7.9","Cell RNA - U-2 OS [nTPM]":"25.2","Cell RNA - U-2197 [nTPM]":"245.9","Cell RNA - U-251 MG [nTPM]":"19.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"232.3","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"893.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"71.7","Brain RNA - basal ganglia [nTPM]":"74.9","Brain RNA - cerebellum [nTPM]":"68.7","Brain RNA - cerebral cortex [nTPM]":"72.6","Brain RNA - hippocampal formation [nTPM]":"64.3","Brain RNA - hypothalamus [nTPM]":"79.2","Brain RNA - medulla oblongata [nTPM]":"83.2","Brain RNA - midbrain [nTPM]":"86.7","Brain RNA - pons [nTPM]":"76.0","Brain RNA - spinal cord [nTPM]":"70.3","Brain RNA - thalamus [nTPM]":"106.2","Brain RNA - white matter [nTPM]":"59.5","Single Cell Type RNA - Adipocytes [nTPM]":"1663.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"365.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.9","Single Cell Type RNA - Astrocytes [nTPM]":"101.9","Single Cell Type RNA - B-cells [nTPM]":"5.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"77.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"766.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"49.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"177.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"279.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"22.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"492.2","Single Cell Type RNA - dendritic cells [nTPM]":"4.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"14.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"747.6","Single Cell Type RNA - Endothelial cells [nTPM]":"677.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"35.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"433.7","Single Cell Type RNA - Fibroblasts [nTPM]":"967.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.9","Single Cell Type RNA - granulocytes [nTPM]":"89.2","Single Cell Type RNA - Granulosa cells [nTPM]":"11.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"743.9","Single Cell Type RNA - Hepatocytes [nTPM]":"102.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"109.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"39.3","Single Cell Type RNA - Langerhans cells [nTPM]":"95.0","Single Cell Type RNA - Late spermatids [nTPM]":"57.7","Single Cell Type RNA - Leydig cells [nTPM]":"1398.6","Single Cell Type RNA - Macrophages [nTPM]":"28.6","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"116.2","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"146.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"52.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1934.1","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"159.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.5","Single Cell Type RNA - Sertoli cells [nTPM]":"2327.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"339.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1116.6","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"56.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"809.0","Single Cell Type RNA - T-cells [nTPM]":"21.5","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"163.4"},{"Gene":"TLR4","Gene synonym":["ARMD10","CD284","hToll","TLR-4"],"Ensembl":"ENSG00000136869","Gene description":"Toll like receptor 4","Uniprot":["O00206"],"Chromosome":"9","Position":"117704175-117724735","Protein class":["CD markers","Enzymes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Hydrolase","Receptor"],"Disease involvement":["Age-related macular degeneration","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"38.6","Astrocytes":"50.9","Hepatic stellate cells":"62.8","Hofbauer cells":"38.2","Kupffer cells":"106.0","Macrophages":"64.5","monocytes":"54.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"86.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"dendritic cells":"22.4","granulocytes":"86.8","monocytes":"65.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"60.0","TIME":"43.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004025","HPA049174"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB004025":null,"HPA049174":"AB_2680662"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.79e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"31.1","Tissue RNA - adrenal gland [nTPM]":"11.0","Tissue RNA - amygdala [nTPM]":"12.4","Tissue RNA - appendix [nTPM]":"25.7","Tissue RNA - basal ganglia [nTPM]":"15.7","Tissue RNA - bone marrow [nTPM]":"22.3","Tissue RNA - breast [nTPM]":"12.0","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"8.3","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"4.3","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"10.8","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"10.3","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"16.7","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"13.1","Tissue RNA - medulla oblongata [nTPM]":"12.3","Tissue RNA - midbrain [nTPM]":"14.0","Tissue RNA - ovary [nTPM]":"6.0","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"23.9","Tissue RNA - pons [nTPM]":"12.4","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"7.3","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"3.5","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"10.8","Tissue RNA - spinal cord [nTPM]":"14.9","Tissue RNA - spleen [nTPM]":"32.6","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"14.2","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"5.5","Tissue RNA - tongue [nTPM]":"12.0","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"13.3","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"25.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"11.1","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"10.2","Cell RNA - BJ hTERT+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"3.6","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"26.7","Cell RNA - GAMG [nTPM]":"7.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"3.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"5.7","Cell RNA - HeLa [nTPM]":"5.1","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"19.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"14.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"22.5","Cell RNA - HUVEC TERT2 [nTPM]":"31.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"60.0","Cell RNA - LHCN-M2 [nTPM]":"29.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.9","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"2.4","Cell RNA - PC-3 [nTPM]":"1.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"28.0","Cell RNA - RPMI-8226 [nTPM]":"19.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"28.9","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"6.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.0","Cell RNA - SuSa [nTPM]":"2.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"10.4","Cell RNA - TIME [nTPM]":"43.5","Cell RNA - U-138 MG [nTPM]":"1.4","Cell RNA - U-2 OS [nTPM]":"18.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"4.8","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"19.1","Cell RNA - WM-115 [nTPM]":"15.2","Blood RNA - basophil [nTPM]":"64.0","Blood RNA - classical monocyte [nTPM]":"64.9","Blood RNA - eosinophil [nTPM]":"21.5","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"57.5","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"22.4","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"86.8","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"65.6","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"25.5","Brain RNA - amygdala [nTPM]":"12.4","Brain RNA - basal ganglia [nTPM]":"15.7","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"8.3","Brain RNA - hippocampal formation [nTPM]":"10.3","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"12.3","Brain RNA - midbrain [nTPM]":"14.0","Brain RNA - pons [nTPM]":"12.4","Brain RNA - spinal cord [nTPM]":"14.9","Brain RNA - thalamus [nTPM]":"14.2","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"38.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"50.9","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.2","Single Cell Type RNA - Endothelial cells [nTPM]":"31.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.8","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"62.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"106.0","Single Cell Type RNA - Langerhans cells [nTPM]":"8.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"64.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"54.0","Single Cell Type RNA - Muller glia cells [nTPM]":"8.8","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"6.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"3.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"TMC1","Gene synonym":["DFNA36","DFNB11","DFNB7"],"Ensembl":"ENSG00000165091","Gene description":"Transmembrane channel like 1","Uniprot":["Q8TDI8"],"Chromosome":"9","Position":"72521608-72838297","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Hearing","Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"19.2","Early spermatids":"7.9","Endometrial stromal cells":"5.5","Microglial cells":"5.6","Urothelial cells":"6.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"2.7","HAP1":"5.2","NTERA-2":"1.9","SuSa":"1.0","U-266\/70":"1.3","U-266\/84":"1.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"5.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.3","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"7.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"TMEM126A","Gene synonym":["DKFZp586C1924","OPA7"],"Ensembl":"ENSG00000171202","Gene description":"Transmembrane protein 126A","Uniprot":["Q9H061"],"Chromosome":"11","Position":"85647967-85656547","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046648"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA046648":"AB_2679737"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.60e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"31.9","Tissue RNA - adrenal gland [nTPM]":"28.0","Tissue RNA - amygdala [nTPM]":"40.3","Tissue RNA - appendix [nTPM]":"23.1","Tissue RNA - basal ganglia [nTPM]":"41.5","Tissue RNA - bone marrow [nTPM]":"43.8","Tissue RNA - breast [nTPM]":"33.5","Tissue RNA - cerebellum [nTPM]":"41.4","Tissue RNA - cerebral cortex [nTPM]":"52.3","Tissue RNA - cervix [nTPM]":"21.8","Tissue RNA - choroid plexus [nTPM]":"39.5","Tissue RNA - colon [nTPM]":"28.0","Tissue RNA - duodenum [nTPM]":"32.6","Tissue RNA - endometrium 1 [nTPM]":"20.0","Tissue RNA - epididymis [nTPM]":"31.2","Tissue RNA - esophagus [nTPM]":"27.2","Tissue RNA - fallopian tube [nTPM]":"19.8","Tissue RNA - gallbladder [nTPM]":"19.9","Tissue RNA - heart muscle [nTPM]":"82.1","Tissue RNA - hippocampal formation [nTPM]":"41.4","Tissue RNA - hypothalamus [nTPM]":"42.3","Tissue RNA - kidney [nTPM]":"33.1","Tissue RNA - liver [nTPM]":"49.0","Tissue RNA - lung [nTPM]":"20.5","Tissue RNA - lymph node [nTPM]":"27.3","Tissue RNA - medulla oblongata [nTPM]":"40.7","Tissue RNA - midbrain [nTPM]":"40.6","Tissue RNA - ovary [nTPM]":"21.0","Tissue RNA - pancreas [nTPM]":"33.9","Tissue RNA - parathyroid gland [nTPM]":"26.3","Tissue RNA - pituitary gland [nTPM]":"22.2","Tissue RNA - placenta [nTPM]":"22.8","Tissue RNA - pons [nTPM]":"41.5","Tissue RNA - prostate [nTPM]":"23.5","Tissue RNA - rectum [nTPM]":"29.3","Tissue RNA - retina [nTPM]":"23.9","Tissue RNA - salivary gland [nTPM]":"31.3","Tissue RNA - seminal vesicle [nTPM]":"19.5","Tissue RNA - skeletal muscle [nTPM]":"81.6","Tissue RNA - skin 1 [nTPM]":"19.4","Tissue RNA - small intestine [nTPM]":"26.0","Tissue RNA - smooth muscle [nTPM]":"27.6","Tissue RNA - spinal cord [nTPM]":"41.1","Tissue RNA - spleen [nTPM]":"21.0","Tissue RNA - stomach 1 [nTPM]":"32.8","Tissue RNA - testis [nTPM]":"38.5","Tissue RNA - thalamus [nTPM]":"41.4","Tissue RNA - thymus [nTPM]":"24.2","Tissue RNA - thyroid gland [nTPM]":"26.6","Tissue RNA - tongue [nTPM]":"98.7","Tissue RNA - tonsil [nTPM]":"27.8","Tissue RNA - urinary bladder [nTPM]":"30.5","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"42.4","Cell RNA - A-431 [nTPM]":"46.7","Cell RNA - A549 [nTPM]":"53.2","Cell RNA - AF22 [nTPM]":"50.9","Cell RNA - AN3-CA [nTPM]":"33.0","Cell RNA - ASC diff [nTPM]":"67.2","Cell RNA - ASC TERT1 [nTPM]":"66.7","Cell RNA - BEWO [nTPM]":"38.0","Cell RNA - BJ [nTPM]":"55.9","Cell RNA - BJ hTERT+ [nTPM]":"60.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"82.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"77.6","Cell RNA - CACO-2 [nTPM]":"65.9","Cell RNA - CAPAN-2 [nTPM]":"67.5","Cell RNA - Daudi [nTPM]":"25.4","Cell RNA - EFO-21 [nTPM]":"61.3","Cell RNA - fHDF\/TERT166 [nTPM]":"69.2","Cell RNA - GAMG [nTPM]":"32.0","Cell RNA - HaCaT [nTPM]":"48.9","Cell RNA - HAP1 [nTPM]":"53.8","Cell RNA - HBEC3-KT [nTPM]":"59.5","Cell RNA - HBF TERT88 [nTPM]":"70.7","Cell RNA - HDLM-2 [nTPM]":"72.5","Cell RNA - HEK 293 [nTPM]":"31.0","Cell RNA - HEL [nTPM]":"72.5","Cell RNA - HeLa [nTPM]":"56.9","Cell RNA - Hep G2 [nTPM]":"73.7","Cell RNA - HHSteC [nTPM]":"82.4","Cell RNA - HL-60 [nTPM]":"89.0","Cell RNA - HMC-1 [nTPM]":"54.8","Cell RNA - HSkMC [nTPM]":"58.0","Cell RNA - hTCEpi [nTPM]":"65.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"73.1","Cell RNA - hTERT-HME1 [nTPM]":"78.0","Cell RNA - hTERT-RPE1 [nTPM]":"43.5","Cell RNA - HUVEC TERT2 [nTPM]":"71.6","Cell RNA - JURKAT [nTPM]":"72.2","Cell RNA - K-562 [nTPM]":"51.1","Cell RNA - Karpas-707 [nTPM]":"39.0","Cell RNA - LHCN-M2 [nTPM]":"86.2","Cell RNA - MCF7 [nTPM]":"57.5","Cell RNA - MOLT-4 [nTPM]":"48.6","Cell RNA - NB-4 [nTPM]":"112.3","Cell RNA - NTERA-2 [nTPM]":"48.1","Cell RNA - OE19 [nTPM]":"175.1","Cell RNA - PC-3 [nTPM]":"68.4","Cell RNA - REH [nTPM]":"48.3","Cell RNA - RH-30 [nTPM]":"49.5","Cell RNA - RPMI-8226 [nTPM]":"79.2","Cell RNA - RPTEC TERT1 [nTPM]":"54.5","Cell RNA - RT4 [nTPM]":"57.0","Cell RNA - SCLC-21H [nTPM]":"34.3","Cell RNA - SH-SY5Y [nTPM]":"34.7","Cell RNA - SiHa [nTPM]":"49.4","Cell RNA - SK-BR-3 [nTPM]":"72.9","Cell RNA - SK-MEL-30 [nTPM]":"44.7","Cell RNA - SuSa [nTPM]":"44.5","Cell RNA - T-47d [nTPM]":"88.1","Cell RNA - THP-1 [nTPM]":"64.4","Cell RNA - TIME [nTPM]":"42.8","Cell RNA - U-138 MG [nTPM]":"70.4","Cell RNA - U-2 OS [nTPM]":"52.7","Cell RNA - U-2197 [nTPM]":"134.6","Cell RNA - U-251 MG [nTPM]":"65.3","Cell RNA - U-266\/70 [nTPM]":"27.5","Cell RNA - U-266\/84 [nTPM]":"54.4","Cell RNA - U-698 [nTPM]":"70.4","Cell RNA - U-87 MG [nTPM]":"37.0","Cell RNA - U-937 [nTPM]":"63.6","Cell RNA - WM-115 [nTPM]":"85.2","Blood RNA - basophil [nTPM]":"6.6","Blood RNA - classical monocyte [nTPM]":"23.9","Blood RNA - eosinophil [nTPM]":"11.6","Blood RNA - gdT-cell [nTPM]":"21.2","Blood RNA - intermediate monocyte [nTPM]":"28.1","Blood RNA - MAIT T-cell [nTPM]":"26.0","Blood RNA - memory B-cell [nTPM]":"29.8","Blood RNA - memory CD4 T-cell [nTPM]":"26.4","Blood RNA - memory CD8 T-cell [nTPM]":"23.8","Blood RNA - myeloid DC [nTPM]":"32.9","Blood RNA - naive B-cell [nTPM]":"27.3","Blood RNA - naive CD4 T-cell [nTPM]":"24.4","Blood RNA - naive CD8 T-cell [nTPM]":"24.1","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"15.1","Blood RNA - non-classical monocyte [nTPM]":"23.4","Blood RNA - plasmacytoid DC [nTPM]":"24.7","Blood RNA - T-reg [nTPM]":"26.4","Blood RNA - total PBMC [nTPM]":"18.7","Brain RNA - amygdala [nTPM]":"40.3","Brain RNA - basal ganglia [nTPM]":"41.5","Brain RNA - cerebellum [nTPM]":"41.4","Brain RNA - cerebral cortex [nTPM]":"52.3","Brain RNA - hippocampal formation [nTPM]":"41.4","Brain RNA - hypothalamus [nTPM]":"42.3","Brain RNA - medulla oblongata [nTPM]":"40.7","Brain RNA - midbrain [nTPM]":"40.6","Brain RNA - pons [nTPM]":"41.5","Brain RNA - spinal cord [nTPM]":"41.1","Brain RNA - thalamus [nTPM]":"41.4","Brain RNA - white matter [nTPM]":"42.4","Single Cell Type RNA - Adipocytes [nTPM]":"40.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.3","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"39.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"55.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"87.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.6","Single Cell Type RNA - Bipolar cells [nTPM]":"14.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"62.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"110.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"57.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"67.8","Single Cell Type RNA - dendritic cells [nTPM]":"38.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"146.8","Single Cell Type RNA - Ductal cells [nTPM]":"51.0","Single Cell Type RNA - Early spermatids [nTPM]":"147.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.8","Single Cell Type RNA - Endothelial cells [nTPM]":"36.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"46.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"93.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"73.3","Single Cell Type RNA - Fibroblasts [nTPM]":"40.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.2","Single Cell Type RNA - granulocytes [nTPM]":"37.4","Single Cell Type RNA - Granulosa cells [nTPM]":"33.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"68.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"94.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.6","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"54.4","Single Cell Type RNA - Langerhans cells [nTPM]":"43.3","Single Cell Type RNA - Late spermatids [nTPM]":"80.6","Single Cell Type RNA - Leydig cells [nTPM]":"29.5","Single Cell Type RNA - Macrophages [nTPM]":"48.4","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"66.3","Single Cell Type RNA - Muller glia cells [nTPM]":"35.1","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.5","Single Cell Type RNA - Paneth cells [nTPM]":"34.8","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"45.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"73.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"61.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"109.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"40.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"40.9","Single Cell Type RNA - Spermatocytes [nTPM]":"119.0","Single Cell Type RNA - Spermatogonia [nTPM]":"57.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"49.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"42.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.9","Single Cell Type RNA - T-cells [nTPM]":"42.1","Single Cell Type RNA - Theca cells [nTPM]":"42.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"57.1","Single Cell Type RNA - Urothelial cells [nTPM]":"71.2"},{"Gene":"TMEM132E","Gene synonym":["DFNB99"],"Ensembl":"ENSG00000181291","Gene description":"Transmembrane protein 132E","Uniprot":["Q6IEE7"],"Chromosome":"17","Position":"34579487-34639318","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"17.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"4.1","Inhibitory neurons":"6.4","Oligodendrocyte precursor cells":"13.0","Proximal tubular cells":"11.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"7.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"RPMI-8226":"37.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070608"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA070608":"AB_2686286"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"6.4","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"17.9","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"10.2","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"8.7","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"11.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"4.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"3.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"37.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"6.4","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"17.9","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"10.2","Brain RNA - spinal cord [nTPM]":"8.7","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"11.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TMEM240","Gene synonym":["C1orf70","SCA21"],"Ensembl":"ENSG00000205090","Gene description":"Transmembrane protein 240","Uniprot":["Q5SV17"],"Chromosome":"1","Position":"1534778-1540624","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"6.5","Excitatory neurons":"15.5","Inhibitory neurons":"15.1","Oligodendrocyte precursor cells":"8.0","Sertoli cells":"6.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"8.5","SCLC-21H":"9.3","SH-SY5Y":"11.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066721"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066721":"AB_2732750"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.52e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"10.9","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"12.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"3.9","Tissue RNA - cerebellum [nTPM]":"17.1","Tissue RNA - cerebral cortex [nTPM]":"22.8","Tissue RNA - cervix [nTPM]":"14.8","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"17.4","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"15.1","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"10.6","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"8.2","Tissue RNA - hippocampal formation [nTPM]":"13.1","Tissue RNA - hypothalamus [nTPM]":"7.6","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"7.1","Tissue RNA - midbrain [nTPM]":"8.1","Tissue RNA - ovary [nTPM]":"16.1","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"15.1","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"9.5","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"3.8","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"4.0","Tissue RNA - stomach 1 [nTPM]":"5.7","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"8.5","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"10.8","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"9.6","Cell RNA - A-431 [nTPM]":"0.9","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"5.7","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"3.8","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"3.8","Cell RNA - BJ hTERT+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"3.5","Cell RNA - HEK 293 [nTPM]":"8.5","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"3.6","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"7.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"5.2","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.4","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"3.5","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"1.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"1.2","Cell RNA - REH [nTPM]":"3.3","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"9.3","Cell RNA - SH-SY5Y [nTPM]":"11.2","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"4.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.9","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"1.7","Cell RNA - U-266\/70 [nTPM]":"1.6","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"1.9","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"10.9","Brain RNA - basal ganglia [nTPM]":"12.2","Brain RNA - cerebellum [nTPM]":"17.1","Brain RNA - cerebral cortex [nTPM]":"22.8","Brain RNA - hippocampal formation [nTPM]":"13.1","Brain RNA - hypothalamus [nTPM]":"7.6","Brain RNA - medulla oblongata [nTPM]":"7.1","Brain RNA - midbrain [nTPM]":"8.1","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"8.5","Brain RNA - white matter [nTPM]":"9.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"TMIE","Gene synonym":["DFNB6"],"Ensembl":"ENSG00000181585","Gene description":"Transmembrane inner ear","Uniprot":["Q8NEW7"],"Chromosome":"3","Position":"46694528-46710886","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"19.6","choroid plexus":"10.5","pituitary gland":"9.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"3.8","Spermatocytes":"2.6","Spermatogonia":"3.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"6.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"2.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"T-cells":"2.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"3.1","EFO-21":"2.7","JURKAT":"10.7","SH-SY5Y":"2.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038298"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038298":"AB_10675792"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"14.2","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"14.0","Tissue RNA - cerebral cortex [nTPM]":"18.0","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"10.5","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"19.3","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"19.6","Tissue RNA - midbrain [nTPM]":"15.7","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"19.2","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"16.0","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"18.7","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"3.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"10.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"2.3","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"14.2","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"14.0","Brain RNA - cerebral cortex [nTPM]":"18.0","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"19.3","Brain RNA - medulla oblongata [nTPM]":"19.6","Brain RNA - midbrain [nTPM]":"15.7","Brain RNA - pons [nTPM]":"19.2","Brain RNA - spinal cord [nTPM]":"16.0","Brain RNA - thalamus [nTPM]":"18.7","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"3.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"TMPRSS3","Gene synonym":["DFNB10","DFNB8"],"Ensembl":"ENSG00000160183","Gene description":"Transmembrane serine protease 3","Uniprot":["P57727"],"Chromosome":"21","Position":"42371887-42396091","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"23.7","stomach 1":"14.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"17.7","Cholangiocytes":"24.3","Ductal cells":"16.1","Endometrial ciliated cells":"17.1","Gastric mucus-secreting cells":"23.4","Ionocytes":"16.2","Muller glia cells":"20.4","Respiratory ciliated cells":"39.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"16.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"3.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"3.1"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"U-266\/84":"274.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.64e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"8.7","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"6.3","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"23.7","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"3.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"9.2","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"4.5","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"12.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"32.9","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"66.2","Cell RNA - HeLa [nTPM]":"26.5","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"8.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"14.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"3.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"33.9","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"3.2","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"274.7","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"3.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.5","Single Cell Type RNA - Urothelial cells [nTPM]":"5.0"},{"Gene":"TNC","Gene synonym":["DFNA56","HXB","MGC167029","TN"],"Ensembl":"ENSG00000041982","Gene description":"Tenascin C","Uniprot":["P24821"],"Chromosome":"9","Position":"115019575-115118257","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"smooth muscle":"376.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"160.3","Basal prostatic cells":"72.1","Basal respiratory cells":"150.6","Basal squamous epithelial cells":"126.3","Prostatic glandular cells":"69.2","Smooth muscle cells":"58.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"798.5","hTEC\/SVTERT24-B":"634.4","U-138 MG":"526.0","U-251 MG":"484.5","U-87 MG":"711.8","WM-115":"1253.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004592","HPA004823"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":560000000,"Blood concentration - Conc. blood MS [pg\/L]":"840000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004592":"AB_628342","HPA004823":"AB_1080243"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Tissue RNA - adipose tissue [nTPM]":"61.0","Tissue RNA - adrenal gland [nTPM]":"4.7","Tissue RNA - amygdala [nTPM]":"16.4","Tissue RNA - appendix [nTPM]":"170.4","Tissue RNA - basal ganglia [nTPM]":"28.5","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"41.2","Tissue RNA - cerebellum [nTPM]":"14.0","Tissue RNA - cerebral cortex [nTPM]":"9.8","Tissue RNA - cervix [nTPM]":"43.6","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"174.3","Tissue RNA - duodenum [nTPM]":"16.7","Tissue RNA - endometrium 1 [nTPM]":"106.8","Tissue RNA - epididymis [nTPM]":"12.2","Tissue RNA - esophagus [nTPM]":"23.9","Tissue RNA - fallopian tube [nTPM]":"25.5","Tissue RNA - gallbladder [nTPM]":"14.1","Tissue RNA - heart muscle [nTPM]":"32.6","Tissue RNA - hippocampal formation [nTPM]":"15.6","Tissue RNA - hypothalamus [nTPM]":"34.3","Tissue RNA - kidney [nTPM]":"82.0","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"54.2","Tissue RNA - lymph node [nTPM]":"39.8","Tissue RNA - medulla oblongata [nTPM]":"20.3","Tissue RNA - midbrain [nTPM]":"43.8","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"28.0","Tissue RNA - prostate [nTPM]":"39.1","Tissue RNA - rectum [nTPM]":"28.3","Tissue RNA - retina [nTPM]":"4.8","Tissue RNA - salivary gland [nTPM]":"19.8","Tissue RNA - seminal vesicle [nTPM]":"33.3","Tissue RNA - skeletal muscle [nTPM]":"6.2","Tissue RNA - skin 1 [nTPM]":"25.9","Tissue RNA - small intestine [nTPM]":"56.5","Tissue RNA - smooth muscle [nTPM]":"376.2","Tissue RNA - spinal cord [nTPM]":"15.0","Tissue RNA - spleen [nTPM]":"40.8","Tissue RNA - stomach 1 [nTPM]":"62.4","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"65.4","Tissue RNA - thymus [nTPM]":"17.1","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"22.6","Tissue RNA - urinary bladder [nTPM]":"96.7","Tissue RNA - vagina [nTPM]":"15.9","Tissue RNA - white matter [nTPM]":"20.5","Cell RNA - A-431 [nTPM]":"25.1","Cell RNA - A549 [nTPM]":"6.0","Cell RNA - AF22 [nTPM]":"6.9","Cell RNA - AN3-CA [nTPM]":"1.3","Cell RNA - ASC diff [nTPM]":"37.5","Cell RNA - ASC TERT1 [nTPM]":"10.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"205.7","Cell RNA - BJ hTERT+ [nTPM]":"798.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"425.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"203.6","Cell RNA - CACO-2 [nTPM]":"5.3","Cell RNA - CAPAN-2 [nTPM]":"55.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"32.8","Cell RNA - fHDF\/TERT166 [nTPM]":"291.7","Cell RNA - GAMG [nTPM]":"6.9","Cell RNA - HaCaT [nTPM]":"89.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"12.0","Cell RNA - HBF TERT88 [nTPM]":"241.3","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"3.9","Cell RNA - HSkMC [nTPM]":"6.2","Cell RNA - hTCEpi [nTPM]":"1.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"634.4","Cell RNA - hTERT-HME1 [nTPM]":"289.9","Cell RNA - hTERT-RPE1 [nTPM]":"42.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"11.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"65.2","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"85.3","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"451.9","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"373.3","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"5.9","Cell RNA - SiHa [nTPM]":"91.4","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"19.3","Cell RNA - SuSa [nTPM]":"140.9","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"526.0","Cell RNA - U-2 OS [nTPM]":"88.4","Cell RNA - U-2197 [nTPM]":"94.2","Cell RNA - U-251 MG [nTPM]":"484.5","Cell RNA - U-266\/70 [nTPM]":"14.3","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"711.8","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"1253.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"16.4","Brain RNA - basal ganglia [nTPM]":"28.5","Brain RNA - cerebellum [nTPM]":"14.0","Brain RNA - cerebral cortex [nTPM]":"9.8","Brain RNA - hippocampal formation [nTPM]":"15.6","Brain RNA - hypothalamus [nTPM]":"34.3","Brain RNA - medulla oblongata [nTPM]":"20.3","Brain RNA - midbrain [nTPM]":"43.8","Brain RNA - pons [nTPM]":"28.0","Brain RNA - spinal cord [nTPM]":"15.0","Brain RNA - thalamus [nTPM]":"65.4","Brain RNA - white matter [nTPM]":"20.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"43.5","Single Cell Type RNA - Astrocytes [nTPM]":"160.3","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"72.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"150.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"126.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"14.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"25.8","Single Cell Type RNA - Early spermatids [nTPM]":"15.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"47.8","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"19.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.9","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"4.7","Single Cell Type RNA - Late spermatids [nTPM]":"18.4","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"69.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"58.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"5.8"},{"Gene":"TNFRSF1A","Gene synonym":["CD120a","TNF-R","TNF-R-I","TNF-R55","TNFAR","TNFR1","TNFR60"],"Ensembl":"ENSG00000067182","Gene description":"TNF receptor superfamily member 1A","Uniprot":["P19438"],"Chromosome":"12","Position":"6328757-6342114","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":["Amyloidosis","Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"507.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004102","CAB010309"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":17700,"Blood concentration - Conc. blood MS [pg\/L]":"570000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010309":"AB_2206639","HPA004102":"AB_1846232"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.68e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.70e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Tissue RNA - adipose tissue [nTPM]":"166.5","Tissue RNA - adrenal gland [nTPM]":"133.3","Tissue RNA - amygdala [nTPM]":"33.7","Tissue RNA - appendix [nTPM]":"76.7","Tissue RNA - basal ganglia [nTPM]":"34.4","Tissue RNA - bone marrow [nTPM]":"42.4","Tissue RNA - breast [nTPM]":"120.0","Tissue RNA - cerebellum [nTPM]":"35.3","Tissue RNA - cerebral cortex [nTPM]":"38.6","Tissue RNA - cervix [nTPM]":"105.0","Tissue RNA - choroid plexus [nTPM]":"47.8","Tissue RNA - colon [nTPM]":"114.1","Tissue RNA - duodenum [nTPM]":"101.5","Tissue RNA - endometrium 1 [nTPM]":"111.8","Tissue RNA - epididymis [nTPM]":"23.0","Tissue RNA - esophagus [nTPM]":"105.6","Tissue RNA - fallopian tube [nTPM]":"106.7","Tissue RNA - gallbladder [nTPM]":"88.8","Tissue RNA - heart muscle [nTPM]":"80.6","Tissue RNA - hippocampal formation [nTPM]":"32.4","Tissue RNA - hypothalamus [nTPM]":"40.3","Tissue RNA - kidney [nTPM]":"94.5","Tissue RNA - liver [nTPM]":"176.5","Tissue RNA - lung [nTPM]":"130.7","Tissue RNA - lymph node [nTPM]":"38.1","Tissue RNA - medulla oblongata [nTPM]":"45.7","Tissue RNA - midbrain [nTPM]":"40.4","Tissue RNA - ovary [nTPM]":"90.6","Tissue RNA - pancreas [nTPM]":"57.3","Tissue RNA - parathyroid gland [nTPM]":"53.7","Tissue RNA - pituitary gland [nTPM]":"57.3","Tissue RNA - placenta [nTPM]":"82.4","Tissue RNA - pons [nTPM]":"39.6","Tissue RNA - prostate [nTPM]":"86.9","Tissue RNA - rectum [nTPM]":"56.4","Tissue RNA - retina [nTPM]":"3.5","Tissue RNA - salivary gland [nTPM]":"76.0","Tissue RNA - seminal vesicle [nTPM]":"46.3","Tissue RNA - skeletal muscle [nTPM]":"91.0","Tissue RNA - skin 1 [nTPM]":"103.7","Tissue RNA - small intestine [nTPM]":"109.5","Tissue RNA - smooth muscle [nTPM]":"97.5","Tissue RNA - spinal cord [nTPM]":"40.4","Tissue RNA - spleen [nTPM]":"111.3","Tissue RNA - stomach 1 [nTPM]":"84.4","Tissue RNA - testis [nTPM]":"22.6","Tissue RNA - thalamus [nTPM]":"39.7","Tissue RNA - thymus [nTPM]":"39.2","Tissue RNA - thyroid gland [nTPM]":"97.4","Tissue RNA - tongue [nTPM]":"63.1","Tissue RNA - tonsil [nTPM]":"36.1","Tissue RNA - urinary bladder [nTPM]":"113.2","Tissue RNA - vagina [nTPM]":"113.2","Tissue RNA - white matter [nTPM]":"37.4","Cell RNA - A-431 [nTPM]":"40.2","Cell RNA - A549 [nTPM]":"296.4","Cell RNA - AF22 [nTPM]":"40.9","Cell RNA - AN3-CA [nTPM]":"60.2","Cell RNA - ASC diff [nTPM]":"277.7","Cell RNA - ASC TERT1 [nTPM]":"282.0","Cell RNA - BEWO [nTPM]":"75.7","Cell RNA - BJ [nTPM]":"82.2","Cell RNA - BJ hTERT+ [nTPM]":"143.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"108.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"93.9","Cell RNA - CACO-2 [nTPM]":"34.7","Cell RNA - CAPAN-2 [nTPM]":"153.6","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"28.9","Cell RNA - fHDF\/TERT166 [nTPM]":"179.3","Cell RNA - GAMG [nTPM]":"85.6","Cell RNA - HaCaT [nTPM]":"107.1","Cell RNA - HAP1 [nTPM]":"12.9","Cell RNA - HBEC3-KT [nTPM]":"96.4","Cell RNA - HBF TERT88 [nTPM]":"74.1","Cell RNA - HDLM-2 [nTPM]":"0.8","Cell RNA - HEK 293 [nTPM]":"25.3","Cell RNA - HEL [nTPM]":"20.3","Cell RNA - HeLa [nTPM]":"79.2","Cell RNA - Hep G2 [nTPM]":"82.2","Cell RNA - HHSteC [nTPM]":"245.5","Cell RNA - HL-60 [nTPM]":"104.4","Cell RNA - HMC-1 [nTPM]":"66.9","Cell RNA - HSkMC [nTPM]":"291.8","Cell RNA - hTCEpi [nTPM]":"94.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"90.2","Cell RNA - hTERT-HME1 [nTPM]":"131.4","Cell RNA - hTERT-RPE1 [nTPM]":"250.4","Cell RNA - HUVEC TERT2 [nTPM]":"134.1","Cell RNA - JURKAT [nTPM]":"42.0","Cell RNA - K-562 [nTPM]":"33.7","Cell RNA - Karpas-707 [nTPM]":"29.8","Cell RNA - LHCN-M2 [nTPM]":"126.3","Cell RNA - MCF7 [nTPM]":"57.1","Cell RNA - MOLT-4 [nTPM]":"34.0","Cell RNA - NB-4 [nTPM]":"100.0","Cell RNA - NTERA-2 [nTPM]":"102.1","Cell RNA - OE19 [nTPM]":"146.1","Cell RNA - PC-3 [nTPM]":"87.6","Cell RNA - REH [nTPM]":"27.9","Cell RNA - RH-30 [nTPM]":"66.6","Cell RNA - RPMI-8226 [nTPM]":"32.4","Cell RNA - RPTEC TERT1 [nTPM]":"83.7","Cell RNA - RT4 [nTPM]":"70.7","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"117.8","Cell RNA - SK-BR-3 [nTPM]":"60.9","Cell RNA - SK-MEL-30 [nTPM]":"62.5","Cell RNA - SuSa [nTPM]":"103.6","Cell RNA - T-47d [nTPM]":"16.4","Cell RNA - THP-1 [nTPM]":"111.4","Cell RNA - TIME [nTPM]":"146.0","Cell RNA - U-138 MG [nTPM]":"84.6","Cell RNA - U-2 OS [nTPM]":"71.7","Cell RNA - U-2197 [nTPM]":"64.7","Cell RNA - U-251 MG [nTPM]":"78.4","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"10.6","Cell RNA - U-698 [nTPM]":"12.8","Cell RNA - U-87 MG [nTPM]":"100.5","Cell RNA - U-937 [nTPM]":"95.9","Cell RNA - WM-115 [nTPM]":"107.0","Blood RNA - basophil [nTPM]":"17.1","Blood RNA - classical monocyte [nTPM]":"165.8","Blood RNA - eosinophil [nTPM]":"93.5","Blood RNA - gdT-cell [nTPM]":"62.2","Blood RNA - intermediate monocyte [nTPM]":"130.4","Blood RNA - MAIT T-cell [nTPM]":"60.0","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"25.1","Blood RNA - memory CD8 T-cell [nTPM]":"51.0","Blood RNA - myeloid DC [nTPM]":"123.7","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"22.3","Blood RNA - naive CD8 T-cell [nTPM]":"34.0","Blood RNA - neutrophil [nTPM]":"507.2","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"111.5","Blood RNA - plasmacytoid DC [nTPM]":"31.6","Blood RNA - T-reg [nTPM]":"26.2","Blood RNA - total PBMC [nTPM]":"117.3","Brain RNA - amygdala [nTPM]":"33.7","Brain RNA - basal ganglia [nTPM]":"34.4","Brain RNA - cerebellum [nTPM]":"35.3","Brain RNA - cerebral cortex [nTPM]":"38.6","Brain RNA - hippocampal formation [nTPM]":"32.4","Brain RNA - hypothalamus [nTPM]":"40.3","Brain RNA - medulla oblongata [nTPM]":"45.7","Brain RNA - midbrain [nTPM]":"40.4","Brain RNA - pons [nTPM]":"39.6","Brain RNA - spinal cord [nTPM]":"40.4","Brain RNA - thalamus [nTPM]":"39.7","Brain RNA - white matter [nTPM]":"37.4","Single Cell Type RNA - Adipocytes [nTPM]":"102.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.1","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"4.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"123.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"115.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"127.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"81.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"50.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"35.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"67.2","Single Cell Type RNA - Club cells [nTPM]":"70.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"62.0","Single Cell Type RNA - dendritic cells [nTPM]":"35.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"204.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"98.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"66.5","Single Cell Type RNA - Endothelial cells [nTPM]":"111.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.6","Single Cell Type RNA - Erythroid cells [nTPM]":"30.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"119.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"120.2","Single Cell Type RNA - Fibroblasts [nTPM]":"109.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.3","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"27.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"159.2","Single Cell Type RNA - Hepatocytes [nTPM]":"145.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"176.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"56.8","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"146.7","Single Cell Type RNA - Langerhans cells [nTPM]":"113.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"102.2","Single Cell Type RNA - Macrophages [nTPM]":"102.4","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"127.1","Single Cell Type RNA - Muller glia cells [nTPM]":"15.9","Single Cell Type RNA - NK-cells [nTPM]":"104.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"116.6","Single Cell Type RNA - Paneth cells [nTPM]":"239.4","Single Cell Type RNA - Peritubular cells [nTPM]":"65.8","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"141.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"227.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"96.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"124.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"64.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"89.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"57.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"134.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"148.6","Single Cell Type RNA - T-cells [nTPM]":"31.2","Single Cell Type RNA - Theca cells [nTPM]":"21.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"57.4","Single Cell Type RNA - Urothelial cells [nTPM]":"140.1"},{"Gene":"TNRC6A","Gene synonym":["CAGH26","GW182","KIAA1460","TNRC6"],"Ensembl":"ENSG00000090905","Gene description":"Trinucleotide repeat containing adaptor 6A","Uniprot":["Q8NDV7"],"Chromosome":"16","Position":"24610209-24827632","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["RNA-mediated gene silencing","Translation regulation"],"Molecular function":["RNA-binding"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"289.3","Excitatory neurons":"283.8","Inhibitory neurons":"414.6","Oligodendrocyte precursor cells":"265.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015305","HPA017869"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA015305":"AB_1850454","HPA017869":"AB_1850456"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.2","Tissue RNA - adrenal gland [nTPM]":"21.0","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"6.4","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"14.9","Tissue RNA - cerebellum [nTPM]":"10.8","Tissue RNA - cerebral cortex [nTPM]":"7.1","Tissue RNA - cervix [nTPM]":"17.8","Tissue RNA - choroid plexus [nTPM]":"6.1","Tissue RNA - colon [nTPM]":"17.8","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"23.5","Tissue RNA - epididymis [nTPM]":"11.5","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"17.7","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"13.0","Tissue RNA - lung [nTPM]":"12.8","Tissue RNA - lymph node [nTPM]":"7.1","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"20.6","Tissue RNA - pancreas [nTPM]":"19.2","Tissue RNA - parathyroid gland [nTPM]":"13.2","Tissue RNA - pituitary gland [nTPM]":"22.8","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"7.0","Tissue RNA - salivary gland [nTPM]":"14.9","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"14.0","Tissue RNA - skin 1 [nTPM]":"13.1","Tissue RNA - small intestine [nTPM]":"15.3","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"17.8","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"7.4","Tissue RNA - urinary bladder [nTPM]":"13.0","Tissue RNA - vagina [nTPM]":"13.4","Tissue RNA - white matter [nTPM]":"7.4","Cell RNA - A-431 [nTPM]":"10.1","Cell RNA - A549 [nTPM]":"13.8","Cell RNA - AF22 [nTPM]":"16.0","Cell RNA - AN3-CA [nTPM]":"8.7","Cell RNA - ASC diff [nTPM]":"13.6","Cell RNA - ASC TERT1 [nTPM]":"17.7","Cell RNA - BEWO [nTPM]":"9.1","Cell RNA - BJ [nTPM]":"16.9","Cell RNA - BJ hTERT+ [nTPM]":"13.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.1","Cell RNA - CACO-2 [nTPM]":"10.2","Cell RNA - CAPAN-2 [nTPM]":"8.2","Cell RNA - Daudi [nTPM]":"10.2","Cell RNA - EFO-21 [nTPM]":"7.1","Cell RNA - fHDF\/TERT166 [nTPM]":"17.0","Cell RNA - GAMG [nTPM]":"12.4","Cell RNA - HaCaT [nTPM]":"11.2","Cell RNA - HAP1 [nTPM]":"20.1","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"18.0","Cell RNA - HDLM-2 [nTPM]":"10.4","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"10.2","Cell RNA - HeLa [nTPM]":"16.7","Cell RNA - Hep G2 [nTPM]":"14.1","Cell RNA - HHSteC [nTPM]":"11.7","Cell RNA - HL-60 [nTPM]":"10.5","Cell RNA - HMC-1 [nTPM]":"6.9","Cell RNA - HSkMC [nTPM]":"18.0","Cell RNA - hTCEpi [nTPM]":"7.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.8","Cell RNA - hTERT-HME1 [nTPM]":"10.2","Cell RNA - hTERT-RPE1 [nTPM]":"14.8","Cell RNA - HUVEC TERT2 [nTPM]":"16.7","Cell RNA - JURKAT [nTPM]":"6.6","Cell RNA - K-562 [nTPM]":"15.7","Cell RNA - Karpas-707 [nTPM]":"6.2","Cell RNA - LHCN-M2 [nTPM]":"15.8","Cell RNA - MCF7 [nTPM]":"11.9","Cell RNA - MOLT-4 [nTPM]":"8.8","Cell RNA - NB-4 [nTPM]":"6.9","Cell RNA - NTERA-2 [nTPM]":"23.1","Cell RNA - OE19 [nTPM]":"4.9","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"17.1","Cell RNA - RH-30 [nTPM]":"12.4","Cell RNA - RPMI-8226 [nTPM]":"9.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.1","Cell RNA - RT4 [nTPM]":"9.3","Cell RNA - SCLC-21H [nTPM]":"7.7","Cell RNA - SH-SY5Y [nTPM]":"10.8","Cell RNA - SiHa [nTPM]":"11.8","Cell RNA - SK-BR-3 [nTPM]":"7.2","Cell RNA - SK-MEL-30 [nTPM]":"6.6","Cell RNA - SuSa [nTPM]":"12.1","Cell RNA - T-47d [nTPM]":"8.4","Cell RNA - THP-1 [nTPM]":"6.8","Cell RNA - TIME [nTPM]":"15.5","Cell RNA - U-138 MG [nTPM]":"15.3","Cell RNA - U-2 OS [nTPM]":"10.5","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"12.0","Cell RNA - U-266\/70 [nTPM]":"13.7","Cell RNA - U-266\/84 [nTPM]":"11.6","Cell RNA - U-698 [nTPM]":"16.5","Cell RNA - U-87 MG [nTPM]":"14.3","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"11.3","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"10.8","Brain RNA - cerebral cortex [nTPM]":"7.1","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"7.4","Single Cell Type RNA - Adipocytes [nTPM]":"51.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"60.0","Single Cell Type RNA - Astrocytes [nTPM]":"289.3","Single Cell Type RNA - B-cells [nTPM]":"45.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"97.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"75.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"32.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"118.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - dendritic cells [nTPM]":"49.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"23.6","Single Cell Type RNA - Early spermatids [nTPM]":"17.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"65.5","Single Cell Type RNA - Endothelial cells [nTPM]":"45.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"55.9","Single Cell Type RNA - Erythroid cells [nTPM]":"34.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"283.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.1","Single Cell Type RNA - Fibroblasts [nTPM]":"50.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.8","Single Cell Type RNA - granulocytes [nTPM]":"39.3","Single Cell Type RNA - Granulosa cells [nTPM]":"76.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"60.3","Single Cell Type RNA - Hepatocytes [nTPM]":"115.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.2","Single Cell Type RNA - Horizontal cells [nTPM]":"176.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"414.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.3","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"56.2","Single Cell Type RNA - Langerhans cells [nTPM]":"26.5","Single Cell Type RNA - Late spermatids [nTPM]":"11.3","Single Cell Type RNA - Leydig cells [nTPM]":"69.0","Single Cell Type RNA - Macrophages [nTPM]":"28.7","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"138.7","Single Cell Type RNA - monocytes [nTPM]":"36.1","Single Cell Type RNA - Muller glia cells [nTPM]":"42.0","Single Cell Type RNA - NK-cells [nTPM]":"50.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"265.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"234.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.5","Single Cell Type RNA - Paneth cells [nTPM]":"36.1","Single Cell Type RNA - Peritubular cells [nTPM]":"81.3","Single Cell Type RNA - Plasma cells [nTPM]":"44.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"42.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"81.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"52.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"60.9","Single Cell Type RNA - Spermatocytes [nTPM]":"41.2","Single Cell Type RNA - Spermatogonia [nTPM]":"30.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - T-cells [nTPM]":"39.0","Single Cell Type RNA - Theca cells [nTPM]":"36.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.8","Single Cell Type RNA - Urothelial cells [nTPM]":"17.4"},{"Gene":"TOPORS","Gene synonym":["LUN","RP31","TP53BPL"],"Ensembl":"ENSG00000197579","Gene description":"TOP1 binding arginine\/serine rich protein, E3 ubiquitin ligase","Uniprot":["Q9NS56"],"Chromosome":"9","Position":"32540544-32552586","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"169.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"67.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"67.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"90.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060640","HPA065661"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA060640":"AB_2684334","HPA065661":"AB_2685527"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.07e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.64e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.8","Tissue RNA - adrenal gland [nTPM]":"9.8","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"25.2","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"10.3","Tissue RNA - choroid plexus [nTPM]":"7.3","Tissue RNA - colon [nTPM]":"9.2","Tissue RNA - duodenum [nTPM]":"8.3","Tissue RNA - endometrium 1 [nTPM]":"11.4","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"8.7","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"5.4","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"13.2","Tissue RNA - liver [nTPM]":"16.2","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"9.3","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"15.3","Tissue RNA - pancreas [nTPM]":"8.6","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"9.3","Tissue RNA - retina [nTPM]":"11.5","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"7.2","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"8.8","Tissue RNA - smooth muscle [nTPM]":"11.2","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"14.5","Tissue RNA - thyroid gland [nTPM]":"14.1","Tissue RNA - tongue [nTPM]":"10.4","Tissue RNA - tonsil [nTPM]":"10.1","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"7.2","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"16.6","Cell RNA - A549 [nTPM]":"15.1","Cell RNA - AF22 [nTPM]":"20.4","Cell RNA - AN3-CA [nTPM]":"17.9","Cell RNA - ASC diff [nTPM]":"24.4","Cell RNA - ASC TERT1 [nTPM]":"21.8","Cell RNA - BEWO [nTPM]":"12.9","Cell RNA - BJ [nTPM]":"20.7","Cell RNA - BJ hTERT+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.5","Cell RNA - CACO-2 [nTPM]":"9.5","Cell RNA - CAPAN-2 [nTPM]":"8.3","Cell RNA - Daudi [nTPM]":"26.8","Cell RNA - EFO-21 [nTPM]":"11.7","Cell RNA - fHDF\/TERT166 [nTPM]":"20.8","Cell RNA - GAMG [nTPM]":"14.8","Cell RNA - HaCaT [nTPM]":"10.9","Cell RNA - HAP1 [nTPM]":"24.2","Cell RNA - HBEC3-KT [nTPM]":"23.5","Cell RNA - HBF TERT88 [nTPM]":"23.6","Cell RNA - HDLM-2 [nTPM]":"22.5","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"90.8","Cell RNA - HeLa [nTPM]":"25.2","Cell RNA - Hep G2 [nTPM]":"11.9","Cell RNA - HHSteC [nTPM]":"15.1","Cell RNA - HL-60 [nTPM]":"26.1","Cell RNA - HMC-1 [nTPM]":"24.0","Cell RNA - HSkMC [nTPM]":"17.9","Cell RNA - hTCEpi [nTPM]":"25.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.4","Cell RNA - hTERT-HME1 [nTPM]":"17.1","Cell RNA - hTERT-RPE1 [nTPM]":"20.9","Cell RNA - HUVEC TERT2 [nTPM]":"20.8","Cell RNA - JURKAT [nTPM]":"20.1","Cell RNA - K-562 [nTPM]":"16.1","Cell RNA - Karpas-707 [nTPM]":"13.6","Cell RNA - LHCN-M2 [nTPM]":"27.9","Cell RNA - MCF7 [nTPM]":"8.9","Cell RNA - MOLT-4 [nTPM]":"23.5","Cell RNA - NB-4 [nTPM]":"47.6","Cell RNA - NTERA-2 [nTPM]":"27.2","Cell RNA - OE19 [nTPM]":"12.3","Cell RNA - PC-3 [nTPM]":"15.2","Cell RNA - REH [nTPM]":"23.9","Cell RNA - RH-30 [nTPM]":"18.1","Cell RNA - RPMI-8226 [nTPM]":"12.2","Cell RNA - RPTEC TERT1 [nTPM]":"22.5","Cell RNA - RT4 [nTPM]":"17.2","Cell RNA - SCLC-21H [nTPM]":"10.1","Cell RNA - SH-SY5Y [nTPM]":"16.1","Cell RNA - SiHa [nTPM]":"20.7","Cell RNA - SK-BR-3 [nTPM]":"11.2","Cell RNA - SK-MEL-30 [nTPM]":"13.8","Cell RNA - SuSa [nTPM]":"22.9","Cell RNA - T-47d [nTPM]":"11.3","Cell RNA - THP-1 [nTPM]":"14.7","Cell RNA - TIME [nTPM]":"22.0","Cell RNA - U-138 MG [nTPM]":"18.4","Cell RNA - U-2 OS [nTPM]":"18.6","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"15.5","Cell RNA - U-266\/70 [nTPM]":"9.5","Cell RNA - U-266\/84 [nTPM]":"16.2","Cell RNA - U-698 [nTPM]":"28.5","Cell RNA - U-87 MG [nTPM]":"17.0","Cell RNA - U-937 [nTPM]":"14.8","Cell RNA - WM-115 [nTPM]":"8.4","Blood RNA - basophil [nTPM]":"38.8","Blood RNA - classical monocyte [nTPM]":"10.0","Blood RNA - eosinophil [nTPM]":"21.3","Blood RNA - gdT-cell [nTPM]":"9.6","Blood RNA - intermediate monocyte [nTPM]":"9.8","Blood RNA - MAIT T-cell [nTPM]":"10.3","Blood RNA - memory B-cell [nTPM]":"9.4","Blood RNA - memory CD4 T-cell [nTPM]":"10.4","Blood RNA - memory CD8 T-cell [nTPM]":"11.4","Blood RNA - myeloid DC [nTPM]":"10.2","Blood RNA - naive B-cell [nTPM]":"10.8","Blood RNA - naive CD4 T-cell [nTPM]":"13.9","Blood RNA - naive CD8 T-cell [nTPM]":"13.8","Blood RNA - neutrophil [nTPM]":"67.6","Blood RNA - NK-cell [nTPM]":"15.0","Blood RNA - non-classical monocyte [nTPM]":"13.6","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"13.5","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"5.4","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"69.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"49.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"47.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"61.5","Single Cell Type RNA - Bipolar cells [nTPM]":"46.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"37.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.9","Single Cell Type RNA - dendritic cells [nTPM]":"63.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"25.1","Single Cell Type RNA - Early spermatids [nTPM]":"169.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.1","Single Cell Type RNA - Endothelial cells [nTPM]":"48.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.9","Single Cell Type RNA - Erythroid cells [nTPM]":"66.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.9","Single Cell Type RNA - Fibroblasts [nTPM]":"42.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.5","Single Cell Type RNA - granulocytes [nTPM]":"41.8","Single Cell Type RNA - Granulosa cells [nTPM]":"43.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"24.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.7","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.9","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"19.1","Single Cell Type RNA - Langerhans cells [nTPM]":"35.3","Single Cell Type RNA - Late spermatids [nTPM]":"21.8","Single Cell Type RNA - Leydig cells [nTPM]":"33.2","Single Cell Type RNA - Macrophages [nTPM]":"31.8","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"30.4","Single Cell Type RNA - Muller glia cells [nTPM]":"43.5","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.1","Single Cell Type RNA - Paneth cells [nTPM]":"24.3","Single Cell Type RNA - Peritubular cells [nTPM]":"32.7","Single Cell Type RNA - Plasma cells [nTPM]":"39.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.2","Single Cell Type RNA - Spermatocytes [nTPM]":"54.4","Single Cell Type RNA - Spermatogonia [nTPM]":"53.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"47.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.8","Single Cell Type RNA - T-cells [nTPM]":"55.4","Single Cell Type RNA - Theca cells [nTPM]":"43.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.0","Single Cell Type RNA - Urothelial cells [nTPM]":"49.8"},{"Gene":"TOR1A","Gene synonym":["DQ2","DYT1"],"Ensembl":"ENSG00000136827","Gene description":"Torsin family 1 member A","Uniprot":["O14656"],"Chromosome":"9","Position":"129812942-129824244","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone","Hydrolase"],"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012473","HPA051195"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nuclear membrane","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB012473":"AB_2240792","HPA051195":"AB_2681382"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.45e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.2","Tissue RNA - adrenal gland [nTPM]":"24.2","Tissue RNA - amygdala [nTPM]":"14.3","Tissue RNA - appendix [nTPM]":"20.7","Tissue RNA - basal ganglia [nTPM]":"14.8","Tissue RNA - bone marrow [nTPM]":"34.5","Tissue RNA - breast [nTPM]":"19.6","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"17.7","Tissue RNA - cervix [nTPM]":"18.6","Tissue RNA - choroid plexus [nTPM]":"14.2","Tissue RNA - colon [nTPM]":"20.7","Tissue RNA - duodenum [nTPM]":"16.6","Tissue RNA - endometrium 1 [nTPM]":"20.3","Tissue RNA - epididymis [nTPM]":"19.9","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"17.2","Tissue RNA - gallbladder [nTPM]":"20.6","Tissue RNA - heart muscle [nTPM]":"16.8","Tissue RNA - hippocampal formation [nTPM]":"15.7","Tissue RNA - hypothalamus [nTPM]":"15.9","Tissue RNA - kidney [nTPM]":"20.5","Tissue RNA - liver [nTPM]":"35.9","Tissue RNA - lung [nTPM]":"19.4","Tissue RNA - lymph node [nTPM]":"22.9","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"14.0","Tissue RNA - ovary [nTPM]":"17.2","Tissue RNA - pancreas [nTPM]":"19.5","Tissue RNA - parathyroid gland [nTPM]":"19.4","Tissue RNA - pituitary gland [nTPM]":"14.3","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"14.0","Tissue RNA - prostate [nTPM]":"21.3","Tissue RNA - rectum [nTPM]":"22.3","Tissue RNA - retina [nTPM]":"9.8","Tissue RNA - salivary gland [nTPM]":"17.0","Tissue RNA - seminal vesicle [nTPM]":"23.1","Tissue RNA - skeletal muscle [nTPM]":"16.4","Tissue RNA - skin 1 [nTPM]":"17.8","Tissue RNA - small intestine [nTPM]":"18.8","Tissue RNA - smooth muscle [nTPM]":"25.4","Tissue RNA - spinal cord [nTPM]":"14.1","Tissue RNA - spleen [nTPM]":"18.8","Tissue RNA - stomach 1 [nTPM]":"18.1","Tissue RNA - testis [nTPM]":"9.2","Tissue RNA - thalamus [nTPM]":"15.4","Tissue RNA - thymus [nTPM]":"26.3","Tissue RNA - thyroid gland [nTPM]":"23.8","Tissue RNA - tongue [nTPM]":"14.9","Tissue RNA - tonsil [nTPM]":"19.0","Tissue RNA - urinary bladder [nTPM]":"28.6","Tissue RNA - vagina [nTPM]":"15.6","Tissue RNA - white matter [nTPM]":"14.8","Cell RNA - A-431 [nTPM]":"33.7","Cell RNA - A549 [nTPM]":"49.5","Cell RNA - AF22 [nTPM]":"35.9","Cell RNA - AN3-CA [nTPM]":"41.5","Cell RNA - ASC diff [nTPM]":"53.1","Cell RNA - ASC TERT1 [nTPM]":"51.3","Cell RNA - BEWO [nTPM]":"47.4","Cell RNA - BJ [nTPM]":"76.7","Cell RNA - BJ hTERT+ [nTPM]":"94.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"57.2","Cell RNA - CACO-2 [nTPM]":"32.3","Cell RNA - CAPAN-2 [nTPM]":"48.2","Cell RNA - Daudi [nTPM]":"41.0","Cell RNA - EFO-21 [nTPM]":"44.0","Cell RNA - fHDF\/TERT166 [nTPM]":"99.7","Cell RNA - GAMG [nTPM]":"46.0","Cell RNA - HaCaT [nTPM]":"77.2","Cell RNA - HAP1 [nTPM]":"34.7","Cell RNA - HBEC3-KT [nTPM]":"50.8","Cell RNA - HBF TERT88 [nTPM]":"54.7","Cell RNA - HDLM-2 [nTPM]":"65.7","Cell RNA - HEK 293 [nTPM]":"32.9","Cell RNA - HEL [nTPM]":"36.9","Cell RNA - HeLa [nTPM]":"49.8","Cell RNA - Hep G2 [nTPM]":"32.3","Cell RNA - HHSteC [nTPM]":"66.9","Cell RNA - HL-60 [nTPM]":"82.1","Cell RNA - HMC-1 [nTPM]":"65.5","Cell RNA - HSkMC [nTPM]":"69.8","Cell RNA - hTCEpi [nTPM]":"50.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.5","Cell RNA - hTERT-HME1 [nTPM]":"45.6","Cell RNA - hTERT-RPE1 [nTPM]":"61.5","Cell RNA - HUVEC TERT2 [nTPM]":"73.2","Cell RNA - JURKAT [nTPM]":"65.3","Cell RNA - K-562 [nTPM]":"66.5","Cell RNA - Karpas-707 [nTPM]":"32.3","Cell RNA - LHCN-M2 [nTPM]":"74.6","Cell RNA - MCF7 [nTPM]":"84.3","Cell RNA - MOLT-4 [nTPM]":"58.9","Cell RNA - NB-4 [nTPM]":"79.3","Cell RNA - NTERA-2 [nTPM]":"53.8","Cell RNA - OE19 [nTPM]":"39.2","Cell RNA - PC-3 [nTPM]":"55.6","Cell RNA - REH [nTPM]":"30.5","Cell RNA - RH-30 [nTPM]":"56.5","Cell RNA - RPMI-8226 [nTPM]":"41.9","Cell RNA - RPTEC TERT1 [nTPM]":"54.9","Cell RNA - RT4 [nTPM]":"42.4","Cell RNA - SCLC-21H [nTPM]":"27.0","Cell RNA - SH-SY5Y [nTPM]":"47.6","Cell RNA - SiHa [nTPM]":"79.3","Cell RNA - SK-BR-3 [nTPM]":"30.7","Cell RNA - SK-MEL-30 [nTPM]":"43.3","Cell RNA - SuSa [nTPM]":"40.1","Cell RNA - T-47d [nTPM]":"61.6","Cell RNA - THP-1 [nTPM]":"63.4","Cell RNA - TIME [nTPM]":"65.1","Cell RNA - U-138 MG [nTPM]":"66.1","Cell RNA - U-2 OS [nTPM]":"37.7","Cell RNA - U-2197 [nTPM]":"49.6","Cell RNA - U-251 MG [nTPM]":"59.6","Cell RNA - U-266\/70 [nTPM]":"36.6","Cell RNA - U-266\/84 [nTPM]":"87.0","Cell RNA - U-698 [nTPM]":"37.7","Cell RNA - U-87 MG [nTPM]":"49.0","Cell RNA - U-937 [nTPM]":"46.9","Cell RNA - WM-115 [nTPM]":"54.3","Blood RNA - basophil [nTPM]":"95.5","Blood RNA - classical monocyte [nTPM]":"72.8","Blood RNA - eosinophil [nTPM]":"141.3","Blood RNA - gdT-cell [nTPM]":"57.4","Blood RNA - intermediate monocyte [nTPM]":"68.5","Blood RNA - MAIT T-cell [nTPM]":"48.1","Blood RNA - memory B-cell [nTPM]":"45.5","Blood RNA - memory CD4 T-cell [nTPM]":"48.4","Blood RNA - memory CD8 T-cell [nTPM]":"52.1","Blood RNA - myeloid DC [nTPM]":"61.4","Blood RNA - naive B-cell [nTPM]":"33.5","Blood RNA - naive CD4 T-cell [nTPM]":"40.9","Blood RNA - naive CD8 T-cell [nTPM]":"42.4","Blood RNA - neutrophil [nTPM]":"72.7","Blood RNA - NK-cell [nTPM]":"68.6","Blood RNA - non-classical monocyte [nTPM]":"58.3","Blood RNA - plasmacytoid DC [nTPM]":"56.5","Blood RNA - T-reg [nTPM]":"59.1","Blood RNA - total PBMC [nTPM]":"78.9","Brain RNA - amygdala [nTPM]":"14.3","Brain RNA - basal ganglia [nTPM]":"14.8","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"17.7","Brain RNA - hippocampal formation [nTPM]":"15.7","Brain RNA - hypothalamus [nTPM]":"15.9","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"14.0","Brain RNA - pons [nTPM]":"14.0","Brain RNA - spinal cord [nTPM]":"14.1","Brain RNA - thalamus [nTPM]":"15.4","Brain RNA - white matter [nTPM]":"14.8","Single Cell Type RNA - Adipocytes [nTPM]":"25.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.8","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"17.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"11.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"24.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.9","Single Cell Type RNA - dendritic cells [nTPM]":"39.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"42.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.8","Single Cell Type RNA - Endothelial cells [nTPM]":"24.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"30.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"65.7","Single Cell Type RNA - Fibroblasts [nTPM]":"25.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.0","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"23.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"22.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.2","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.8","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"19.1","Single Cell Type RNA - Langerhans cells [nTPM]":"22.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"27.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"47.6","Single Cell Type RNA - Muller glia cells [nTPM]":"18.5","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.1","Single Cell Type RNA - Paneth cells [nTPM]":"18.9","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"23.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.3","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"53.4","Single Cell Type RNA - T-cells [nTPM]":"25.5","Single Cell Type RNA - Theca cells [nTPM]":"23.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.4","Single Cell Type RNA - Urothelial cells [nTPM]":"19.6"},{"Gene":"TP53","Gene synonym":["LFS1","p53"],"Ensembl":"ENSG00000141510","Gene description":"Tumor protein p53","Uniprot":["P04637"],"Chromosome":"17","Position":"7661779-7687538","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors","Transporters"],"Biological process":["Apoptosis","Biological rhythms","Cell cycle","Host-virus interaction","Necrosis","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002973","CAB039238","CAB039239","HPA051244","HPA063532","CAB072876","CAB079965"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria","Cytosol"],"Antibody RRID":{"CAB002973":"AB_2206626","CAB039238":null,"CAB039239":null,"CAB072876":"AB_2665731","CAB079965":null,"HPA051244":"AB_2681403","HPA063532":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.3","Tissue RNA - adrenal gland [nTPM]":"13.8","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"22.5","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"16.5","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"29.0","Tissue RNA - duodenum [nTPM]":"18.9","Tissue RNA - endometrium 1 [nTPM]":"24.5","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"28.8","Tissue RNA - fallopian tube [nTPM]":"31.3","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"16.5","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"34.6","Tissue RNA - medulla oblongata [nTPM]":"18.7","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"27.3","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"27.5","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"15.3","Tissue RNA - skeletal muscle [nTPM]":"12.3","Tissue RNA - skin 1 [nTPM]":"37.4","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"24.6","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"31.1","Tissue RNA - stomach 1 [nTPM]":"22.6","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"12.3","Tissue RNA - thymus [nTPM]":"47.2","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"45.4","Tissue RNA - urinary bladder [nTPM]":"20.8","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"81.5","Cell RNA - A549 [nTPM]":"145.3","Cell RNA - AF22 [nTPM]":"81.1","Cell RNA - AN3-CA [nTPM]":"57.3","Cell RNA - ASC diff [nTPM]":"37.3","Cell RNA - ASC TERT1 [nTPM]":"43.9","Cell RNA - BEWO [nTPM]":"82.8","Cell RNA - BJ [nTPM]":"28.4","Cell RNA - BJ hTERT+ [nTPM]":"66.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"78.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"100.2","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"40.6","Cell RNA - Daudi [nTPM]":"190.5","Cell RNA - EFO-21 [nTPM]":"126.9","Cell RNA - fHDF\/TERT166 [nTPM]":"58.7","Cell RNA - GAMG [nTPM]":"77.6","Cell RNA - HaCaT [nTPM]":"174.9","Cell RNA - HAP1 [nTPM]":"119.7","Cell RNA - HBEC3-KT [nTPM]":"80.4","Cell RNA - HBF TERT88 [nTPM]":"72.8","Cell RNA - HDLM-2 [nTPM]":"42.7","Cell RNA - HEK 293 [nTPM]":"76.5","Cell RNA - HEL [nTPM]":"77.6","Cell RNA - HeLa [nTPM]":"76.8","Cell RNA - Hep G2 [nTPM]":"70.9","Cell RNA - HHSteC [nTPM]":"111.5","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"37.0","Cell RNA - HSkMC [nTPM]":"55.7","Cell RNA - hTCEpi [nTPM]":"93.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.9","Cell RNA - hTERT-HME1 [nTPM]":"106.5","Cell RNA - hTERT-RPE1 [nTPM]":"45.6","Cell RNA - HUVEC TERT2 [nTPM]":"79.4","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"3.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"41.5","Cell RNA - MCF7 [nTPM]":"145.1","Cell RNA - MOLT-4 [nTPM]":"130.0","Cell RNA - NB-4 [nTPM]":"96.3","Cell RNA - NTERA-2 [nTPM]":"80.2","Cell RNA - OE19 [nTPM]":"10.4","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"252.2","Cell RNA - RH-30 [nTPM]":"56.1","Cell RNA - RPMI-8226 [nTPM]":"66.2","Cell RNA - RPTEC TERT1 [nTPM]":"59.4","Cell RNA - RT4 [nTPM]":"87.3","Cell RNA - SCLC-21H [nTPM]":"46.0","Cell RNA - SH-SY5Y [nTPM]":"80.5","Cell RNA - SiHa [nTPM]":"94.1","Cell RNA - SK-BR-3 [nTPM]":"62.6","Cell RNA - SK-MEL-30 [nTPM]":"24.3","Cell RNA - SuSa [nTPM]":"39.4","Cell RNA - T-47d [nTPM]":"109.2","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"100.7","Cell RNA - U-138 MG [nTPM]":"91.6","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"48.3","Cell RNA - U-266\/70 [nTPM]":"47.6","Cell RNA - U-266\/84 [nTPM]":"37.9","Cell RNA - U-698 [nTPM]":"82.5","Cell RNA - U-87 MG [nTPM]":"23.6","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"80.1","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"21.2","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"21.7","Blood RNA - MAIT T-cell [nTPM]":"15.9","Blood RNA - memory B-cell [nTPM]":"21.5","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"30.3","Blood RNA - naive B-cell [nTPM]":"19.1","Blood RNA - naive CD4 T-cell [nTPM]":"13.7","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"17.5","Blood RNA - non-classical monocyte [nTPM]":"19.3","Blood RNA - plasmacytoid DC [nTPM]":"27.3","Blood RNA - T-reg [nTPM]":"17.3","Blood RNA - total PBMC [nTPM]":"14.7","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"16.5","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"18.7","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"12.3","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"21.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"15.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.9","Single Cell Type RNA - dendritic cells [nTPM]":"24.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"24.8","Single Cell Type RNA - Early spermatids [nTPM]":"12.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"24.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.7","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"31.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"27.8","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"19.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - T-cells [nTPM]":"16.5","Single Cell Type RNA - Theca cells [nTPM]":"27.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"TPP1","Gene synonym":["CLN2","LPIC","SCAR7","TPP-1"],"Ensembl":"ENSG00000166340","Gene description":"Tripeptidyl peptidase 1","Uniprot":["O14773"],"Chromosome":"11","Position":"6612768-6619448","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Neuronal ceroid lipofuscinosis","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"261.6","Kupffer cells":"376.5","Macrophages":"219.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037709","HPA044868"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9500000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037709":"AB_10672913","HPA044868":"AB_2679122"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.31e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.46e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"74.7","Tissue RNA - adrenal gland [nTPM]":"145.9","Tissue RNA - amygdala [nTPM]":"71.0","Tissue RNA - appendix [nTPM]":"74.6","Tissue RNA - basal ganglia [nTPM]":"81.0","Tissue RNA - bone marrow [nTPM]":"111.7","Tissue RNA - breast [nTPM]":"44.3","Tissue RNA - cerebellum [nTPM]":"80.3","Tissue RNA - cerebral cortex [nTPM]":"81.4","Tissue RNA - cervix [nTPM]":"53.8","Tissue RNA - choroid plexus [nTPM]":"120.1","Tissue RNA - colon [nTPM]":"59.1","Tissue RNA - duodenum [nTPM]":"59.9","Tissue RNA - endometrium 1 [nTPM]":"74.0","Tissue RNA - epididymis [nTPM]":"43.1","Tissue RNA - esophagus [nTPM]":"39.5","Tissue RNA - fallopian tube [nTPM]":"47.1","Tissue RNA - gallbladder [nTPM]":"65.1","Tissue RNA - heart muscle [nTPM]":"56.3","Tissue RNA - hippocampal formation [nTPM]":"70.6","Tissue RNA - hypothalamus [nTPM]":"78.4","Tissue RNA - kidney [nTPM]":"71.6","Tissue RNA - liver [nTPM]":"92.7","Tissue RNA - lung [nTPM]":"81.5","Tissue RNA - lymph node [nTPM]":"77.7","Tissue RNA - medulla oblongata [nTPM]":"85.2","Tissue RNA - midbrain [nTPM]":"82.6","Tissue RNA - ovary [nTPM]":"49.7","Tissue RNA - pancreas [nTPM]":"36.2","Tissue RNA - parathyroid gland [nTPM]":"54.2","Tissue RNA - pituitary gland [nTPM]":"63.6","Tissue RNA - placenta [nTPM]":"94.2","Tissue RNA - pons [nTPM]":"81.0","Tissue RNA - prostate [nTPM]":"38.9","Tissue RNA - rectum [nTPM]":"59.7","Tissue RNA - retina [nTPM]":"48.5","Tissue RNA - salivary gland [nTPM]":"42.5","Tissue RNA - seminal vesicle [nTPM]":"57.5","Tissue RNA - skeletal muscle [nTPM]":"31.4","Tissue RNA - skin 1 [nTPM]":"39.5","Tissue RNA - small intestine [nTPM]":"73.3","Tissue RNA - smooth muscle [nTPM]":"92.0","Tissue RNA - spinal cord [nTPM]":"74.7","Tissue RNA - spleen [nTPM]":"135.0","Tissue RNA - stomach 1 [nTPM]":"48.4","Tissue RNA - testis [nTPM]":"20.0","Tissue RNA - thalamus [nTPM]":"83.3","Tissue RNA - thymus [nTPM]":"47.4","Tissue RNA - thyroid gland [nTPM]":"45.7","Tissue RNA - tongue [nTPM]":"39.0","Tissue RNA - tonsil [nTPM]":"60.9","Tissue RNA - urinary bladder [nTPM]":"68.4","Tissue RNA - vagina [nTPM]":"42.8","Tissue RNA - white matter [nTPM]":"90.4","Cell RNA - A-431 [nTPM]":"26.1","Cell RNA - A549 [nTPM]":"48.1","Cell RNA - AF22 [nTPM]":"25.9","Cell RNA - AN3-CA [nTPM]":"50.5","Cell RNA - ASC diff [nTPM]":"309.9","Cell RNA - ASC TERT1 [nTPM]":"160.1","Cell RNA - BEWO [nTPM]":"21.8","Cell RNA - BJ [nTPM]":"50.9","Cell RNA - BJ hTERT+ [nTPM]":"220.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.0","Cell RNA - CACO-2 [nTPM]":"20.1","Cell RNA - CAPAN-2 [nTPM]":"122.5","Cell RNA - Daudi [nTPM]":"37.4","Cell RNA - EFO-21 [nTPM]":"32.6","Cell RNA - fHDF\/TERT166 [nTPM]":"136.6","Cell RNA - GAMG [nTPM]":"220.2","Cell RNA - HaCaT [nTPM]":"85.8","Cell RNA - HAP1 [nTPM]":"48.3","Cell RNA - HBEC3-KT [nTPM]":"68.7","Cell RNA - HBF TERT88 [nTPM]":"57.9","Cell RNA - HDLM-2 [nTPM]":"37.3","Cell RNA - HEK 293 [nTPM]":"27.6","Cell RNA - HEL [nTPM]":"32.2","Cell RNA - HeLa [nTPM]":"23.8","Cell RNA - Hep G2 [nTPM]":"54.9","Cell RNA - HHSteC [nTPM]":"210.9","Cell RNA - HL-60 [nTPM]":"45.8","Cell RNA - HMC-1 [nTPM]":"182.6","Cell RNA - HSkMC [nTPM]":"231.8","Cell RNA - hTCEpi [nTPM]":"104.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.9","Cell RNA - hTERT-HME1 [nTPM]":"102.6","Cell RNA - hTERT-RPE1 [nTPM]":"240.4","Cell RNA - HUVEC TERT2 [nTPM]":"158.8","Cell RNA - JURKAT [nTPM]":"32.9","Cell RNA - K-562 [nTPM]":"59.8","Cell RNA - Karpas-707 [nTPM]":"124.6","Cell RNA - LHCN-M2 [nTPM]":"110.4","Cell RNA - MCF7 [nTPM]":"30.2","Cell RNA - MOLT-4 [nTPM]":"16.6","Cell RNA - NB-4 [nTPM]":"52.4","Cell RNA - NTERA-2 [nTPM]":"18.0","Cell RNA - OE19 [nTPM]":"61.5","Cell RNA - PC-3 [nTPM]":"57.1","Cell RNA - REH [nTPM]":"36.1","Cell RNA - RH-30 [nTPM]":"21.6","Cell RNA - RPMI-8226 [nTPM]":"77.0","Cell RNA - RPTEC TERT1 [nTPM]":"62.8","Cell RNA - RT4 [nTPM]":"38.2","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"20.4","Cell RNA - SiHa [nTPM]":"52.6","Cell RNA - SK-BR-3 [nTPM]":"44.6","Cell RNA - SK-MEL-30 [nTPM]":"91.0","Cell RNA - SuSa [nTPM]":"76.5","Cell RNA - T-47d [nTPM]":"30.8","Cell RNA - THP-1 [nTPM]":"79.7","Cell RNA - TIME [nTPM]":"188.0","Cell RNA - U-138 MG [nTPM]":"119.7","Cell RNA - U-2 OS [nTPM]":"33.1","Cell RNA - U-2197 [nTPM]":"101.1","Cell RNA - U-251 MG [nTPM]":"19.8","Cell RNA - U-266\/70 [nTPM]":"92.3","Cell RNA - U-266\/84 [nTPM]":"95.3","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"139.8","Cell RNA - U-937 [nTPM]":"101.7","Cell RNA - WM-115 [nTPM]":"64.5","Blood RNA - basophil [nTPM]":"67.0","Blood RNA - classical monocyte [nTPM]":"167.1","Blood RNA - eosinophil [nTPM]":"38.2","Blood RNA - gdT-cell [nTPM]":"39.9","Blood RNA - intermediate monocyte [nTPM]":"171.2","Blood RNA - MAIT T-cell [nTPM]":"30.0","Blood RNA - memory B-cell [nTPM]":"35.1","Blood RNA - memory CD4 T-cell [nTPM]":"31.4","Blood RNA - memory CD8 T-cell [nTPM]":"41.0","Blood RNA - myeloid DC [nTPM]":"185.9","Blood RNA - naive B-cell [nTPM]":"37.0","Blood RNA - naive CD4 T-cell [nTPM]":"20.1","Blood RNA - naive CD8 T-cell [nTPM]":"27.2","Blood RNA - neutrophil [nTPM]":"27.5","Blood RNA - NK-cell [nTPM]":"29.1","Blood RNA - non-classical monocyte [nTPM]":"125.1","Blood RNA - plasmacytoid DC [nTPM]":"93.1","Blood RNA - T-reg [nTPM]":"60.3","Blood RNA - total PBMC [nTPM]":"138.8","Brain RNA - amygdala [nTPM]":"71.0","Brain RNA - basal ganglia [nTPM]":"81.0","Brain RNA - cerebellum [nTPM]":"80.3","Brain RNA - cerebral cortex [nTPM]":"81.4","Brain RNA - hippocampal formation [nTPM]":"70.6","Brain RNA - hypothalamus [nTPM]":"78.4","Brain RNA - medulla oblongata [nTPM]":"85.2","Brain RNA - midbrain [nTPM]":"82.6","Brain RNA - pons [nTPM]":"81.0","Brain RNA - spinal cord [nTPM]":"74.7","Brain RNA - thalamus [nTPM]":"83.3","Brain RNA - white matter [nTPM]":"90.4","Single Cell Type RNA - Adipocytes [nTPM]":"32.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.3","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"53.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"24.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"26.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.4","Single Cell Type RNA - dendritic cells [nTPM]":"71.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"55.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"42.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.2","Single Cell Type RNA - Endothelial cells [nTPM]":"40.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.7","Single Cell Type RNA - Erythroid cells [nTPM]":"37.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.3","Single Cell Type RNA - Fibroblasts [nTPM]":"40.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.8","Single Cell Type RNA - granulocytes [nTPM]":"62.2","Single Cell Type RNA - Granulosa cells [nTPM]":"25.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"75.7","Single Cell Type RNA - Hepatocytes [nTPM]":"81.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"261.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.3","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"376.5","Single Cell Type RNA - Langerhans cells [nTPM]":"126.5","Single Cell Type RNA - Late spermatids [nTPM]":"11.2","Single Cell Type RNA - Leydig cells [nTPM]":"27.1","Single Cell Type RNA - Macrophages [nTPM]":"219.8","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"156.0","Single Cell Type RNA - Muller glia cells [nTPM]":"37.9","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.4","Single Cell Type RNA - Paneth cells [nTPM]":"44.1","Single Cell Type RNA - Peritubular cells [nTPM]":"26.4","Single Cell Type RNA - Plasma cells [nTPM]":"26.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"99.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"51.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.0","Single Cell Type RNA - T-cells [nTPM]":"42.2","Single Cell Type RNA - Theca cells [nTPM]":"24.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.5","Single Cell Type RNA - Urothelial cells [nTPM]":"26.5"},{"Gene":"TPRN","Gene synonym":["C9orf75","DFNB79","FLJ90254"],"Ensembl":"ENSG00000176058","Gene description":"Taperin","Uniprot":["Q4KMQ1"],"Chromosome":"9","Position":"137191617-137204193","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"56.4","pancreas":"91.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"177.7","Proximal enterocytes":"95.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"61.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"23.6"},"Antibody":["HPA020899","HPA076667"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA020899":"AB_1845835","HPA076667":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.13e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.16e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"24.3","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"37.8","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"29.9","Tissue RNA - cerebral cortex [nTPM]":"33.1","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"15.1","Tissue RNA - colon [nTPM]":"25.4","Tissue RNA - duodenum [nTPM]":"22.0","Tissue RNA - endometrium 1 [nTPM]":"4.7","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"20.5","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"10.7","Tissue RNA - hippocampal formation [nTPM]":"23.5","Tissue RNA - hypothalamus [nTPM]":"23.7","Tissue RNA - kidney [nTPM]":"19.1","Tissue RNA - liver [nTPM]":"24.3","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"33.1","Tissue RNA - midbrain [nTPM]":"32.4","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"91.4","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"28.2","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"6.2","Tissue RNA - skin 1 [nTPM]":"15.6","Tissue RNA - small intestine [nTPM]":"26.0","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"20.8","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"29.3","Tissue RNA - testis [nTPM]":"9.3","Tissue RNA - thalamus [nTPM]":"31.9","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"5.5","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"7.8","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"56.4","Cell RNA - A-431 [nTPM]":"10.2","Cell RNA - A549 [nTPM]":"11.4","Cell RNA - AF22 [nTPM]":"3.8","Cell RNA - AN3-CA [nTPM]":"17.0","Cell RNA - ASC diff [nTPM]":"5.2","Cell RNA - ASC TERT1 [nTPM]":"5.5","Cell RNA - BEWO [nTPM]":"30.1","Cell RNA - BJ [nTPM]":"7.0","Cell RNA - BJ hTERT+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.9","Cell RNA - CACO-2 [nTPM]":"38.5","Cell RNA - CAPAN-2 [nTPM]":"12.1","Cell RNA - Daudi [nTPM]":"18.6","Cell RNA - EFO-21 [nTPM]":"10.1","Cell RNA - fHDF\/TERT166 [nTPM]":"3.6","Cell RNA - GAMG [nTPM]":"9.2","Cell RNA - HaCaT [nTPM]":"30.4","Cell RNA - HAP1 [nTPM]":"7.9","Cell RNA - HBEC3-KT [nTPM]":"3.9","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"11.9","Cell RNA - HEK 293 [nTPM]":"11.1","Cell RNA - HEL [nTPM]":"8.7","Cell RNA - HeLa [nTPM]":"17.5","Cell RNA - Hep G2 [nTPM]":"25.5","Cell RNA - HHSteC [nTPM]":"7.9","Cell RNA - HL-60 [nTPM]":"13.5","Cell RNA - HMC-1 [nTPM]":"10.8","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"7.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"4.3","Cell RNA - hTERT-RPE1 [nTPM]":"4.6","Cell RNA - HUVEC TERT2 [nTPM]":"4.5","Cell RNA - JURKAT [nTPM]":"8.2","Cell RNA - K-562 [nTPM]":"16.1","Cell RNA - Karpas-707 [nTPM]":"6.4","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"61.9","Cell RNA - MOLT-4 [nTPM]":"8.9","Cell RNA - NB-4 [nTPM]":"29.0","Cell RNA - NTERA-2 [nTPM]":"13.5","Cell RNA - OE19 [nTPM]":"55.5","Cell RNA - PC-3 [nTPM]":"14.8","Cell RNA - REH [nTPM]":"26.3","Cell RNA - RH-30 [nTPM]":"9.1","Cell RNA - RPMI-8226 [nTPM]":"28.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.9","Cell RNA - RT4 [nTPM]":"21.0","Cell RNA - SCLC-21H [nTPM]":"24.4","Cell RNA - SH-SY5Y [nTPM]":"8.9","Cell RNA - SiHa [nTPM]":"10.8","Cell RNA - SK-BR-3 [nTPM]":"49.6","Cell RNA - SK-MEL-30 [nTPM]":"13.0","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"57.8","Cell RNA - THP-1 [nTPM]":"21.0","Cell RNA - TIME [nTPM]":"5.0","Cell RNA - U-138 MG [nTPM]":"12.7","Cell RNA - U-2 OS [nTPM]":"6.0","Cell RNA - U-2197 [nTPM]":"20.1","Cell RNA - U-251 MG [nTPM]":"15.1","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"11.0","Cell RNA - U-698 [nTPM]":"9.7","Cell RNA - U-87 MG [nTPM]":"9.1","Cell RNA - U-937 [nTPM]":"12.1","Cell RNA - WM-115 [nTPM]":"7.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"24.3","Brain RNA - basal ganglia [nTPM]":"37.8","Brain RNA - cerebellum [nTPM]":"29.9","Brain RNA - cerebral cortex [nTPM]":"33.1","Brain RNA - hippocampal formation [nTPM]":"23.5","Brain RNA - hypothalamus [nTPM]":"23.7","Brain RNA - medulla oblongata [nTPM]":"33.1","Brain RNA - midbrain [nTPM]":"32.4","Brain RNA - pons [nTPM]":"28.2","Brain RNA - spinal cord [nTPM]":"20.8","Brain RNA - thalamus [nTPM]":"31.9","Brain RNA - white matter [nTPM]":"56.4","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"19.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"2.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.4","Single Cell Type RNA - dendritic cells [nTPM]":"8.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"177.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"3.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"19.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.6","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"5.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"12.4","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.3","Single Cell Type RNA - Paneth cells [nTPM]":"39.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"95.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"4.5","Single Cell Type RNA - Theca cells [nTPM]":"10.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"TRAK1","Gene synonym":["KIAA1042","MILT1","OIP106"],"Ensembl":"ENSG00000182606","Gene description":"Trafficking kinesin protein 1","Uniprot":["Q9UPV9"],"Chromosome":"3","Position":"42013802-42225890","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"168.9","skeletal muscle":"262.4","tongue":"202.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"173.0","Cardiomyocytes":"262.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RT4":"165.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005853","HPA011367"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA005853":"AB_1854778","HPA011367":"AB_2668495"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.84e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Tissue RNA - adipose tissue [nTPM]":"26.0","Tissue RNA - adrenal gland [nTPM]":"13.1","Tissue RNA - amygdala [nTPM]":"23.0","Tissue RNA - appendix [nTPM]":"17.1","Tissue RNA - basal ganglia [nTPM]":"26.2","Tissue RNA - bone marrow [nTPM]":"18.2","Tissue RNA - breast [nTPM]":"18.0","Tissue RNA - cerebellum [nTPM]":"28.5","Tissue RNA - cerebral cortex [nTPM]":"27.7","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"27.8","Tissue RNA - colon [nTPM]":"27.1","Tissue RNA - duodenum [nTPM]":"34.5","Tissue RNA - endometrium 1 [nTPM]":"12.2","Tissue RNA - epididymis [nTPM]":"10.4","Tissue RNA - esophagus [nTPM]":"29.3","Tissue RNA - fallopian tube [nTPM]":"19.8","Tissue RNA - gallbladder [nTPM]":"26.9","Tissue RNA - heart muscle [nTPM]":"168.9","Tissue RNA - hippocampal formation [nTPM]":"24.2","Tissue RNA - hypothalamus [nTPM]":"19.5","Tissue RNA - kidney [nTPM]":"20.1","Tissue RNA - liver [nTPM]":"15.3","Tissue RNA - lung [nTPM]":"24.1","Tissue RNA - lymph node [nTPM]":"22.8","Tissue RNA - medulla oblongata [nTPM]":"24.4","Tissue RNA - midbrain [nTPM]":"30.3","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"13.1","Tissue RNA - parathyroid gland [nTPM]":"32.2","Tissue RNA - pituitary gland [nTPM]":"17.7","Tissue RNA - placenta [nTPM]":"15.3","Tissue RNA - pons [nTPM]":"21.6","Tissue RNA - prostate [nTPM]":"15.4","Tissue RNA - rectum [nTPM]":"25.4","Tissue RNA - retina [nTPM]":"96.7","Tissue RNA - salivary gland [nTPM]":"44.1","Tissue RNA - seminal vesicle [nTPM]":"13.1","Tissue RNA - skeletal muscle [nTPM]":"262.4","Tissue RNA - skin 1 [nTPM]":"45.1","Tissue RNA - small intestine [nTPM]":"42.0","Tissue RNA - smooth muscle [nTPM]":"16.8","Tissue RNA - spinal cord [nTPM]":"19.1","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"61.0","Tissue RNA - testis [nTPM]":"12.1","Tissue RNA - thalamus [nTPM]":"26.0","Tissue RNA - thymus [nTPM]":"17.9","Tissue RNA - thyroid gland [nTPM]":"31.4","Tissue RNA - tongue [nTPM]":"202.6","Tissue RNA - tonsil [nTPM]":"22.6","Tissue RNA - urinary bladder [nTPM]":"33.8","Tissue RNA - vagina [nTPM]":"18.4","Tissue RNA - white matter [nTPM]":"21.4","Cell RNA - A-431 [nTPM]":"22.2","Cell RNA - A549 [nTPM]":"19.2","Cell RNA - AF22 [nTPM]":"37.9","Cell RNA - AN3-CA [nTPM]":"16.4","Cell RNA - ASC diff [nTPM]":"25.6","Cell RNA - ASC TERT1 [nTPM]":"24.9","Cell RNA - BEWO [nTPM]":"48.9","Cell RNA - BJ [nTPM]":"29.5","Cell RNA - BJ hTERT+ [nTPM]":"33.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.6","Cell RNA - CACO-2 [nTPM]":"12.8","Cell RNA - CAPAN-2 [nTPM]":"30.7","Cell RNA - Daudi [nTPM]":"43.9","Cell RNA - EFO-21 [nTPM]":"15.1","Cell RNA - fHDF\/TERT166 [nTPM]":"75.2","Cell RNA - GAMG [nTPM]":"20.4","Cell RNA - HaCaT [nTPM]":"10.7","Cell RNA - HAP1 [nTPM]":"26.5","Cell RNA - HBEC3-KT [nTPM]":"68.8","Cell RNA - HBF TERT88 [nTPM]":"20.6","Cell RNA - HDLM-2 [nTPM]":"39.6","Cell RNA - HEK 293 [nTPM]":"18.8","Cell RNA - HEL [nTPM]":"30.4","Cell RNA - HeLa [nTPM]":"19.9","Cell RNA - Hep G2 [nTPM]":"35.6","Cell RNA - HHSteC [nTPM]":"12.8","Cell RNA - HL-60 [nTPM]":"34.6","Cell RNA - HMC-1 [nTPM]":"22.9","Cell RNA - HSkMC [nTPM]":"21.4","Cell RNA - hTCEpi [nTPM]":"28.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.9","Cell RNA - hTERT-HME1 [nTPM]":"38.0","Cell RNA - hTERT-RPE1 [nTPM]":"28.1","Cell RNA - HUVEC TERT2 [nTPM]":"38.6","Cell RNA - JURKAT [nTPM]":"11.6","Cell RNA - K-562 [nTPM]":"15.7","Cell RNA - Karpas-707 [nTPM]":"34.4","Cell RNA - LHCN-M2 [nTPM]":"24.4","Cell RNA - MCF7 [nTPM]":"9.2","Cell RNA - MOLT-4 [nTPM]":"3.7","Cell RNA - NB-4 [nTPM]":"18.1","Cell RNA - NTERA-2 [nTPM]":"16.4","Cell RNA - OE19 [nTPM]":"60.4","Cell RNA - PC-3 [nTPM]":"14.8","Cell RNA - REH [nTPM]":"16.1","Cell RNA - RH-30 [nTPM]":"14.1","Cell RNA - RPMI-8226 [nTPM]":"36.8","Cell RNA - RPTEC TERT1 [nTPM]":"26.3","Cell RNA - RT4 [nTPM]":"165.3","Cell RNA - SCLC-21H [nTPM]":"23.8","Cell RNA - SH-SY5Y [nTPM]":"27.9","Cell RNA - SiHa [nTPM]":"11.3","Cell RNA - SK-BR-3 [nTPM]":"16.3","Cell RNA - SK-MEL-30 [nTPM]":"16.2","Cell RNA - SuSa [nTPM]":"31.4","Cell RNA - T-47d [nTPM]":"14.6","Cell RNA - THP-1 [nTPM]":"29.3","Cell RNA - TIME [nTPM]":"39.6","Cell RNA - U-138 MG [nTPM]":"16.6","Cell RNA - U-2 OS [nTPM]":"19.2","Cell RNA - U-2197 [nTPM]":"99.0","Cell RNA - U-251 MG [nTPM]":"17.4","Cell RNA - U-266\/70 [nTPM]":"25.7","Cell RNA - U-266\/84 [nTPM]":"23.0","Cell RNA - U-698 [nTPM]":"38.9","Cell RNA - U-87 MG [nTPM]":"18.2","Cell RNA - U-937 [nTPM]":"30.2","Cell RNA - WM-115 [nTPM]":"16.4","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"3.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"23.0","Brain RNA - basal ganglia [nTPM]":"26.2","Brain RNA - cerebellum [nTPM]":"28.5","Brain RNA - cerebral cortex [nTPM]":"27.7","Brain RNA - hippocampal formation [nTPM]":"24.2","Brain RNA - hypothalamus [nTPM]":"19.5","Brain RNA - medulla oblongata [nTPM]":"24.4","Brain RNA - midbrain [nTPM]":"30.3","Brain RNA - pons [nTPM]":"21.6","Brain RNA - spinal cord [nTPM]":"19.1","Brain RNA - thalamus [nTPM]":"26.0","Brain RNA - white matter [nTPM]":"21.4","Single Cell Type RNA - Adipocytes [nTPM]":"27.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.4","Single Cell Type RNA - Astrocytes [nTPM]":"173.0","Single Cell Type RNA - B-cells [nTPM]":"23.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"22.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"262.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"38.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"100.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.0","Single Cell Type RNA - dendritic cells [nTPM]":"13.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"61.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"53.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.8","Single Cell Type RNA - Endothelial cells [nTPM]":"23.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.8","Single Cell Type RNA - Erythroid cells [nTPM]":"6.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"62.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.3","Single Cell Type RNA - Fibroblasts [nTPM]":"14.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"81.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"70.0","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"11.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"10.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.7","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"81.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.5","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"33.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"23.3","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"97.4","Single Cell Type RNA - monocytes [nTPM]":"17.9","Single Cell Type RNA - Muller glia cells [nTPM]":"27.8","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"105.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"64.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.2","Single Cell Type RNA - Paneth cells [nTPM]":"37.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"5.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"97.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"80.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"139.9","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"3.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - T-cells [nTPM]":"7.5","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.6","Single Cell Type RNA - Urothelial cells [nTPM]":"27.0"},{"Gene":"TRAPPC12","Gene synonym":["CGI-87","TTC-15","TTC15"],"Ensembl":"ENSG00000171853","Gene description":"Trafficking protein particle complex 12","Uniprot":["Q8WVT3"],"Chromosome":"2","Position":"3379675-3485094","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"96.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"293.9","Late spermatids":"504.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034799","HPA043196"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA034799":"AB_10600920","HPA043196":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.80e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.15e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.7","Tissue RNA - adrenal gland [nTPM]":"26.0","Tissue RNA - amygdala [nTPM]":"13.9","Tissue RNA - appendix [nTPM]":"10.9","Tissue RNA - basal ganglia [nTPM]":"14.4","Tissue RNA - bone marrow [nTPM]":"10.1","Tissue RNA - breast [nTPM]":"21.8","Tissue RNA - cerebellum [nTPM]":"15.0","Tissue RNA - cerebral cortex [nTPM]":"23.3","Tissue RNA - cervix [nTPM]":"20.2","Tissue RNA - choroid plexus [nTPM]":"13.5","Tissue RNA - colon [nTPM]":"27.9","Tissue RNA - duodenum [nTPM]":"10.1","Tissue RNA - endometrium 1 [nTPM]":"23.7","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"23.0","Tissue RNA - fallopian tube [nTPM]":"22.2","Tissue RNA - gallbladder [nTPM]":"10.4","Tissue RNA - heart muscle [nTPM]":"46.7","Tissue RNA - hippocampal formation [nTPM]":"14.8","Tissue RNA - hypothalamus [nTPM]":"15.9","Tissue RNA - kidney [nTPM]":"22.6","Tissue RNA - liver [nTPM]":"28.0","Tissue RNA - lung [nTPM]":"17.1","Tissue RNA - lymph node [nTPM]":"16.0","Tissue RNA - medulla oblongata [nTPM]":"15.9","Tissue RNA - midbrain [nTPM]":"14.1","Tissue RNA - ovary [nTPM]":"21.4","Tissue RNA - pancreas [nTPM]":"26.2","Tissue RNA - parathyroid gland [nTPM]":"18.4","Tissue RNA - pituitary gland [nTPM]":"26.7","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"17.1","Tissue RNA - prostate [nTPM]":"20.6","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"9.1","Tissue RNA - salivary gland [nTPM]":"25.8","Tissue RNA - seminal vesicle [nTPM]":"10.0","Tissue RNA - skeletal muscle [nTPM]":"45.8","Tissue RNA - skin 1 [nTPM]":"35.7","Tissue RNA - small intestine [nTPM]":"21.2","Tissue RNA - smooth muscle [nTPM]":"5.2","Tissue RNA - spinal cord [nTPM]":"14.6","Tissue RNA - spleen [nTPM]":"22.1","Tissue RNA - stomach 1 [nTPM]":"28.4","Tissue RNA - testis [nTPM]":"96.6","Tissue RNA - thalamus [nTPM]":"14.8","Tissue RNA - thymus [nTPM]":"15.7","Tissue RNA - thyroid gland [nTPM]":"24.7","Tissue RNA - tongue [nTPM]":"6.4","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"26.1","Tissue RNA - vagina [nTPM]":"18.9","Tissue RNA - white matter [nTPM]":"15.5","Cell RNA - A-431 [nTPM]":"16.4","Cell RNA - A549 [nTPM]":"28.0","Cell RNA - AF22 [nTPM]":"9.1","Cell RNA - AN3-CA [nTPM]":"10.4","Cell RNA - ASC diff [nTPM]":"19.9","Cell RNA - ASC TERT1 [nTPM]":"24.5","Cell RNA - BEWO [nTPM]":"23.9","Cell RNA - BJ [nTPM]":"26.6","Cell RNA - BJ hTERT+ [nTPM]":"6.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.2","Cell RNA - CACO-2 [nTPM]":"17.5","Cell RNA - CAPAN-2 [nTPM]":"13.6","Cell RNA - Daudi [nTPM]":"18.8","Cell RNA - EFO-21 [nTPM]":"28.6","Cell RNA - fHDF\/TERT166 [nTPM]":"9.0","Cell RNA - GAMG [nTPM]":"6.7","Cell RNA - HaCaT [nTPM]":"20.8","Cell RNA - HAP1 [nTPM]":"10.5","Cell RNA - HBEC3-KT [nTPM]":"11.9","Cell RNA - HBF TERT88 [nTPM]":"3.1","Cell RNA - HDLM-2 [nTPM]":"22.8","Cell RNA - HEK 293 [nTPM]":"39.5","Cell RNA - HEL [nTPM]":"16.2","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"60.8","Cell RNA - HHSteC [nTPM]":"9.0","Cell RNA - HL-60 [nTPM]":"20.4","Cell RNA - HMC-1 [nTPM]":"28.0","Cell RNA - HSkMC [nTPM]":"18.1","Cell RNA - hTCEpi [nTPM]":"9.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.5","Cell RNA - hTERT-HME1 [nTPM]":"21.2","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"6.7","Cell RNA - JURKAT [nTPM]":"21.5","Cell RNA - K-562 [nTPM]":"25.5","Cell RNA - Karpas-707 [nTPM]":"10.0","Cell RNA - LHCN-M2 [nTPM]":"13.5","Cell RNA - MCF7 [nTPM]":"22.5","Cell RNA - MOLT-4 [nTPM]":"20.6","Cell RNA - NB-4 [nTPM]":"34.9","Cell RNA - NTERA-2 [nTPM]":"22.1","Cell RNA - OE19 [nTPM]":"7.3","Cell RNA - PC-3 [nTPM]":"39.4","Cell RNA - REH [nTPM]":"15.4","Cell RNA - RH-30 [nTPM]":"12.4","Cell RNA - RPMI-8226 [nTPM]":"15.3","Cell RNA - RPTEC TERT1 [nTPM]":"8.1","Cell RNA - RT4 [nTPM]":"13.5","Cell RNA - SCLC-21H [nTPM]":"23.2","Cell RNA - SH-SY5Y [nTPM]":"37.8","Cell RNA - SiHa [nTPM]":"10.6","Cell RNA - SK-BR-3 [nTPM]":"11.8","Cell RNA - SK-MEL-30 [nTPM]":"18.5","Cell RNA - SuSa [nTPM]":"4.0","Cell RNA - T-47d [nTPM]":"13.9","Cell RNA - THP-1 [nTPM]":"16.3","Cell RNA - TIME [nTPM]":"17.2","Cell RNA - U-138 MG [nTPM]":"18.6","Cell RNA - U-2 OS [nTPM]":"10.6","Cell RNA - U-2197 [nTPM]":"18.7","Cell RNA - U-251 MG [nTPM]":"23.6","Cell RNA - U-266\/70 [nTPM]":"28.5","Cell RNA - U-266\/84 [nTPM]":"22.4","Cell RNA - U-698 [nTPM]":"15.0","Cell RNA - U-87 MG [nTPM]":"21.8","Cell RNA - U-937 [nTPM]":"15.9","Cell RNA - WM-115 [nTPM]":"10.5","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"4.3","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"13.9","Brain RNA - basal ganglia [nTPM]":"14.4","Brain RNA - cerebellum [nTPM]":"15.0","Brain RNA - cerebral cortex [nTPM]":"23.3","Brain RNA - hippocampal formation [nTPM]":"14.8","Brain RNA - hypothalamus [nTPM]":"15.9","Brain RNA - medulla oblongata [nTPM]":"15.9","Brain RNA - midbrain [nTPM]":"14.1","Brain RNA - pons [nTPM]":"17.1","Brain RNA - spinal cord [nTPM]":"14.6","Brain RNA - thalamus [nTPM]":"14.8","Brain RNA - white matter [nTPM]":"15.5","Single Cell Type RNA - Adipocytes [nTPM]":"18.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"59.4","Single Cell Type RNA - B-cells [nTPM]":"20.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"31.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"68.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.3","Single Cell Type RNA - dendritic cells [nTPM]":"16.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"21.7","Single Cell Type RNA - Early spermatids [nTPM]":"293.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.4","Single Cell Type RNA - Endothelial cells [nTPM]":"18.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"56.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.2","Single Cell Type RNA - Fibroblasts [nTPM]":"23.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.5","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"22.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"16.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.9","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"62.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.7","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.9","Single Cell Type RNA - Langerhans cells [nTPM]":"10.0","Single Cell Type RNA - Late spermatids [nTPM]":"504.5","Single Cell Type RNA - Leydig cells [nTPM]":"26.4","Single Cell Type RNA - Macrophages [nTPM]":"20.7","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"28.5","Single Cell Type RNA - Muller glia cells [nTPM]":"42.6","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"52.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"56.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.9","Single Cell Type RNA - Paneth cells [nTPM]":"11.9","Single Cell Type RNA - Peritubular cells [nTPM]":"24.0","Single Cell Type RNA - Plasma cells [nTPM]":"19.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.7","Single Cell Type RNA - Spermatocytes [nTPM]":"125.2","Single Cell Type RNA - Spermatogonia [nTPM]":"26.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.6","Single Cell Type RNA - T-cells [nTPM]":"14.4","Single Cell Type RNA - Theca cells [nTPM]":"33.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.7","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"TRAPPC2L","Gene synonym":["HSPC176"],"Ensembl":"ENSG00000167515","Gene description":"Trafficking protein particle complex 2 like","Uniprot":["Q9UL33"],"Chromosome":"16","Position":"88856220-88862686","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"403.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041714"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041714":"AB_10793930"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.75e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"55.4","Tissue RNA - adrenal gland [nTPM]":"134.3","Tissue RNA - amygdala [nTPM]":"55.1","Tissue RNA - appendix [nTPM]":"30.9","Tissue RNA - basal ganglia [nTPM]":"56.7","Tissue RNA - bone marrow [nTPM]":"36.9","Tissue RNA - breast [nTPM]":"51.5","Tissue RNA - cerebellum [nTPM]":"57.4","Tissue RNA - cerebral cortex [nTPM]":"69.8","Tissue RNA - cervix [nTPM]":"49.1","Tissue RNA - choroid plexus [nTPM]":"55.2","Tissue RNA - colon [nTPM]":"46.0","Tissue RNA - duodenum [nTPM]":"25.3","Tissue RNA - endometrium 1 [nTPM]":"46.7","Tissue RNA - epididymis [nTPM]":"60.3","Tissue RNA - esophagus [nTPM]":"53.8","Tissue RNA - fallopian tube [nTPM]":"44.1","Tissue RNA - gallbladder [nTPM]":"19.9","Tissue RNA - heart muscle [nTPM]":"66.4","Tissue RNA - hippocampal formation [nTPM]":"57.8","Tissue RNA - hypothalamus [nTPM]":"61.9","Tissue RNA - kidney [nTPM]":"53.5","Tissue RNA - liver [nTPM]":"46.5","Tissue RNA - lung [nTPM]":"42.7","Tissue RNA - lymph node [nTPM]":"31.1","Tissue RNA - medulla oblongata [nTPM]":"57.5","Tissue RNA - midbrain [nTPM]":"57.9","Tissue RNA - ovary [nTPM]":"55.8","Tissue RNA - pancreas [nTPM]":"48.8","Tissue RNA - parathyroid gland [nTPM]":"58.1","Tissue RNA - pituitary gland [nTPM]":"45.3","Tissue RNA - placenta [nTPM]":"20.4","Tissue RNA - pons [nTPM]":"59.1","Tissue RNA - prostate [nTPM]":"39.2","Tissue RNA - rectum [nTPM]":"23.8","Tissue RNA - retina [nTPM]":"25.6","Tissue RNA - salivary gland [nTPM]":"48.0","Tissue RNA - seminal vesicle [nTPM]":"20.5","Tissue RNA - skeletal muscle [nTPM]":"96.8","Tissue RNA - skin 1 [nTPM]":"58.5","Tissue RNA - small intestine [nTPM]":"39.1","Tissue RNA - smooth muscle [nTPM]":"18.1","Tissue RNA - spinal cord [nTPM]":"60.0","Tissue RNA - spleen [nTPM]":"52.7","Tissue RNA - stomach 1 [nTPM]":"62.8","Tissue RNA - testis [nTPM]":"122.0","Tissue RNA - thalamus [nTPM]":"56.9","Tissue RNA - thymus [nTPM]":"50.0","Tissue RNA - thyroid gland [nTPM]":"41.8","Tissue RNA - tongue [nTPM]":"70.7","Tissue RNA - tonsil [nTPM]":"27.2","Tissue RNA - urinary bladder [nTPM]":"48.5","Tissue RNA - vagina [nTPM]":"47.3","Tissue RNA - white matter [nTPM]":"65.4","Cell RNA - A-431 [nTPM]":"69.9","Cell RNA - A549 [nTPM]":"47.9","Cell RNA - AF22 [nTPM]":"79.6","Cell RNA - AN3-CA [nTPM]":"60.8","Cell RNA - ASC diff [nTPM]":"58.5","Cell RNA - ASC TERT1 [nTPM]":"73.9","Cell RNA - BEWO [nTPM]":"81.5","Cell RNA - BJ [nTPM]":"61.5","Cell RNA - BJ hTERT+ [nTPM]":"69.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"92.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.4","Cell RNA - CACO-2 [nTPM]":"133.6","Cell RNA - CAPAN-2 [nTPM]":"89.6","Cell RNA - Daudi [nTPM]":"53.4","Cell RNA - EFO-21 [nTPM]":"105.8","Cell RNA - fHDF\/TERT166 [nTPM]":"78.6","Cell RNA - GAMG [nTPM]":"97.7","Cell RNA - HaCaT [nTPM]":"73.3","Cell RNA - HAP1 [nTPM]":"109.5","Cell RNA - HBEC3-KT [nTPM]":"88.5","Cell RNA - HBF TERT88 [nTPM]":"67.0","Cell RNA - HDLM-2 [nTPM]":"46.9","Cell RNA - HEK 293 [nTPM]":"65.7","Cell RNA - HEL [nTPM]":"35.3","Cell RNA - HeLa [nTPM]":"46.1","Cell RNA - Hep G2 [nTPM]":"172.7","Cell RNA - HHSteC [nTPM]":"86.3","Cell RNA - HL-60 [nTPM]":"101.4","Cell RNA - HMC-1 [nTPM]":"27.5","Cell RNA - HSkMC [nTPM]":"72.2","Cell RNA - hTCEpi [nTPM]":"54.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"125.4","Cell RNA - hTERT-HME1 [nTPM]":"63.1","Cell RNA - hTERT-RPE1 [nTPM]":"52.4","Cell RNA - HUVEC TERT2 [nTPM]":"75.7","Cell RNA - JURKAT [nTPM]":"118.7","Cell RNA - K-562 [nTPM]":"108.2","Cell RNA - Karpas-707 [nTPM]":"41.4","Cell RNA - LHCN-M2 [nTPM]":"64.3","Cell RNA - MCF7 [nTPM]":"216.2","Cell RNA - MOLT-4 [nTPM]":"136.1","Cell RNA - NB-4 [nTPM]":"311.7","Cell RNA - NTERA-2 [nTPM]":"80.3","Cell RNA - OE19 [nTPM]":"133.4","Cell RNA - PC-3 [nTPM]":"88.6","Cell RNA - REH [nTPM]":"128.9","Cell RNA - RH-30 [nTPM]":"65.9","Cell RNA - RPMI-8226 [nTPM]":"55.4","Cell RNA - RPTEC TERT1 [nTPM]":"73.1","Cell RNA - RT4 [nTPM]":"79.6","Cell RNA - SCLC-21H [nTPM]":"85.8","Cell RNA - SH-SY5Y [nTPM]":"42.2","Cell RNA - SiHa [nTPM]":"207.6","Cell RNA - SK-BR-3 [nTPM]":"63.5","Cell RNA - SK-MEL-30 [nTPM]":"59.0","Cell RNA - SuSa [nTPM]":"43.6","Cell RNA - T-47d [nTPM]":"162.5","Cell RNA - THP-1 [nTPM]":"106.3","Cell RNA - TIME [nTPM]":"60.3","Cell RNA - U-138 MG [nTPM]":"61.1","Cell RNA - U-2 OS [nTPM]":"66.7","Cell RNA - U-2197 [nTPM]":"81.1","Cell RNA - U-251 MG [nTPM]":"71.2","Cell RNA - U-266\/70 [nTPM]":"57.9","Cell RNA - U-266\/84 [nTPM]":"106.6","Cell RNA - U-698 [nTPM]":"254.5","Cell RNA - U-87 MG [nTPM]":"73.3","Cell RNA - U-937 [nTPM]":"148.0","Cell RNA - WM-115 [nTPM]":"74.5","Blood RNA - basophil [nTPM]":"39.2","Blood RNA - classical monocyte [nTPM]":"136.3","Blood RNA - eosinophil [nTPM]":"40.8","Blood RNA - gdT-cell [nTPM]":"113.0","Blood RNA - intermediate monocyte [nTPM]":"114.5","Blood RNA - MAIT T-cell [nTPM]":"115.0","Blood RNA - memory B-cell [nTPM]":"154.2","Blood RNA - memory CD4 T-cell [nTPM]":"129.8","Blood RNA - memory CD8 T-cell [nTPM]":"124.1","Blood RNA - myeloid DC [nTPM]":"135.1","Blood RNA - naive B-cell [nTPM]":"137.9","Blood RNA - naive CD4 T-cell [nTPM]":"120.8","Blood RNA - naive CD8 T-cell [nTPM]":"103.5","Blood RNA - neutrophil [nTPM]":"23.9","Blood RNA - NK-cell [nTPM]":"94.6","Blood RNA - non-classical monocyte [nTPM]":"114.8","Blood RNA - plasmacytoid DC [nTPM]":"162.5","Blood RNA - T-reg [nTPM]":"178.0","Blood RNA - total PBMC [nTPM]":"162.9","Brain RNA - amygdala [nTPM]":"55.1","Brain RNA - basal ganglia [nTPM]":"56.7","Brain RNA - cerebellum [nTPM]":"57.4","Brain RNA - cerebral cortex [nTPM]":"69.8","Brain RNA - hippocampal formation [nTPM]":"57.8","Brain RNA - hypothalamus [nTPM]":"61.9","Brain RNA - medulla oblongata [nTPM]":"57.5","Brain RNA - midbrain [nTPM]":"57.9","Brain RNA - pons [nTPM]":"59.1","Brain RNA - spinal cord [nTPM]":"60.0","Brain RNA - thalamus [nTPM]":"56.9","Brain RNA - white matter [nTPM]":"65.4","Single Cell Type RNA - Adipocytes [nTPM]":"66.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"82.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"58.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"51.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"57.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"115.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.3","Single Cell Type RNA - Bipolar cells [nTPM]":"34.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"80.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"106.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"121.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"92.9","Single Cell Type RNA - Club cells [nTPM]":"81.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"93.8","Single Cell Type RNA - dendritic cells [nTPM]":"58.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"75.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"240.7","Single Cell Type RNA - Ductal cells [nTPM]":"134.7","Single Cell Type RNA - Early spermatids [nTPM]":"219.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"60.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"53.4","Single Cell Type RNA - Endothelial cells [nTPM]":"60.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"62.1","Single Cell Type RNA - Erythroid cells [nTPM]":"42.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"154.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"141.5","Single Cell Type RNA - Fibroblasts [nTPM]":"79.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"72.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"50.5","Single Cell Type RNA - granulocytes [nTPM]":"36.1","Single Cell Type RNA - Granulosa cells [nTPM]":"55.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"62.8","Single Cell Type RNA - Hepatocytes [nTPM]":"123.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"226.7","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"78.5","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"91.0","Single Cell Type RNA - Langerhans cells [nTPM]":"69.6","Single Cell Type RNA - Late spermatids [nTPM]":"403.2","Single Cell Type RNA - Leydig cells [nTPM]":"74.0","Single Cell Type RNA - Macrophages [nTPM]":"68.4","Single Cell Type RNA - Melanocytes [nTPM]":"81.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"134.4","Single Cell Type RNA - Muller glia cells [nTPM]":"87.3","Single Cell Type RNA - NK-cells [nTPM]":"79.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"137.4","Single Cell Type RNA - Paneth cells [nTPM]":"76.3","Single Cell Type RNA - Peritubular cells [nTPM]":"58.3","Single Cell Type RNA - Plasma cells [nTPM]":"92.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"122.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"271.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"93.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.5","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.7","Single Cell Type RNA - Spermatocytes [nTPM]":"210.7","Single Cell Type RNA - Spermatogonia [nTPM]":"123.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"86.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"64.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"77.6","Single Cell Type RNA - T-cells [nTPM]":"61.2","Single Cell Type RNA - Theca cells [nTPM]":"64.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"86.8","Single Cell Type RNA - Urothelial cells [nTPM]":"62.5"},{"Gene":"TREX1","Gene synonym":["AGS1","DRN3"],"Ensembl":"ENSG00000213689","Gene description":"Three prime repair exonuclease 1","Uniprot":["Q9NSU2"],"Chromosome":"3","Position":"48465811-48467645","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Exonuclease","Hydrolase","Nuclease"],"Disease involvement":["Aicardi-Goutieres syndrome","Disease variant","Neurodegeneration","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"53.6","Club cells":"24.5","Ionocytes":"40.7","Langerhans cells":"22.6","Melanocytes":"24.9","Respiratory ciliated cells":"29.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+ RasG12V":"67.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035437","HPA046721"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035437":"AB_10672092","HPA046721":"AB_2732531"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"14.3","Tissue RNA - amygdala [nTPM]":"32.7","Tissue RNA - appendix [nTPM]":"16.5","Tissue RNA - basal ganglia [nTPM]":"33.4","Tissue RNA - bone marrow [nTPM]":"28.7","Tissue RNA - breast [nTPM]":"12.2","Tissue RNA - cerebellum [nTPM]":"33.2","Tissue RNA - cerebral cortex [nTPM]":"42.1","Tissue RNA - cervix [nTPM]":"13.8","Tissue RNA - choroid plexus [nTPM]":"39.8","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"11.1","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"11.4","Tissue RNA - esophagus [nTPM]":"19.2","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"13.8","Tissue RNA - heart muscle [nTPM]":"10.7","Tissue RNA - hippocampal formation [nTPM]":"33.0","Tissue RNA - hypothalamus [nTPM]":"32.7","Tissue RNA - kidney [nTPM]":"12.2","Tissue RNA - liver [nTPM]":"12.8","Tissue RNA - lung [nTPM]":"13.8","Tissue RNA - lymph node [nTPM]":"26.6","Tissue RNA - medulla oblongata [nTPM]":"33.0","Tissue RNA - midbrain [nTPM]":"34.2","Tissue RNA - ovary [nTPM]":"7.4","Tissue RNA - pancreas [nTPM]":"13.1","Tissue RNA - parathyroid gland [nTPM]":"11.3","Tissue RNA - pituitary gland [nTPM]":"20.6","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"34.3","Tissue RNA - prostate [nTPM]":"16.6","Tissue RNA - rectum [nTPM]":"9.9","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"36.5","Tissue RNA - seminal vesicle [nTPM]":"15.4","Tissue RNA - skeletal muscle [nTPM]":"9.7","Tissue RNA - skin 1 [nTPM]":"26.4","Tissue RNA - small intestine [nTPM]":"12.0","Tissue RNA - smooth muscle [nTPM]":"7.0","Tissue RNA - spinal cord [nTPM]":"33.8","Tissue RNA - spleen [nTPM]":"25.0","Tissue RNA - stomach 1 [nTPM]":"13.7","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"33.5","Tissue RNA - thymus [nTPM]":"18.1","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"13.8","Tissue RNA - tonsil [nTPM]":"18.1","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"33.7","Cell RNA - A-431 [nTPM]":"19.2","Cell RNA - A549 [nTPM]":"18.1","Cell RNA - AF22 [nTPM]":"13.3","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"18.1","Cell RNA - ASC TERT1 [nTPM]":"17.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"6.7","Cell RNA - BJ hTERT+ [nTPM]":"29.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"67.5","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"21.8","Cell RNA - Daudi [nTPM]":"23.8","Cell RNA - EFO-21 [nTPM]":"11.7","Cell RNA - fHDF\/TERT166 [nTPM]":"24.4","Cell RNA - GAMG [nTPM]":"44.8","Cell RNA - HaCaT [nTPM]":"21.4","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"27.2","Cell RNA - HBF TERT88 [nTPM]":"6.7","Cell RNA - HDLM-2 [nTPM]":"19.9","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"13.5","Cell RNA - HeLa [nTPM]":"58.1","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"20.1","Cell RNA - HL-60 [nTPM]":"12.8","Cell RNA - HMC-1 [nTPM]":"9.3","Cell RNA - HSkMC [nTPM]":"16.2","Cell RNA - hTCEpi [nTPM]":"2.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.9","Cell RNA - hTERT-HME1 [nTPM]":"9.8","Cell RNA - hTERT-RPE1 [nTPM]":"9.8","Cell RNA - HUVEC TERT2 [nTPM]":"20.4","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"32.6","Cell RNA - LHCN-M2 [nTPM]":"20.7","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"17.3","Cell RNA - NB-4 [nTPM]":"8.6","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"11.0","Cell RNA - PC-3 [nTPM]":"11.2","Cell RNA - REH [nTPM]":"14.4","Cell RNA - RH-30 [nTPM]":"4.9","Cell RNA - RPMI-8226 [nTPM]":"43.2","Cell RNA - RPTEC TERT1 [nTPM]":"13.4","Cell RNA - RT4 [nTPM]":"3.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"8.1","Cell RNA - SiHa [nTPM]":"21.8","Cell RNA - SK-BR-3 [nTPM]":"29.6","Cell RNA - SK-MEL-30 [nTPM]":"15.4","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"20.3","Cell RNA - TIME [nTPM]":"22.2","Cell RNA - U-138 MG [nTPM]":"8.5","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"21.8","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"26.4","Cell RNA - U-266\/84 [nTPM]":"16.9","Cell RNA - U-698 [nTPM]":"10.4","Cell RNA - U-87 MG [nTPM]":"21.5","Cell RNA - U-937 [nTPM]":"25.4","Cell RNA - WM-115 [nTPM]":"7.5","Blood RNA - basophil [nTPM]":"7.7","Blood RNA - classical monocyte [nTPM]":"142.3","Blood RNA - eosinophil [nTPM]":"11.0","Blood RNA - gdT-cell [nTPM]":"32.6","Blood RNA - intermediate monocyte [nTPM]":"119.2","Blood RNA - MAIT T-cell [nTPM]":"18.7","Blood RNA - memory B-cell [nTPM]":"86.8","Blood RNA - memory CD4 T-cell [nTPM]":"43.0","Blood RNA - memory CD8 T-cell [nTPM]":"31.4","Blood RNA - myeloid DC [nTPM]":"125.9","Blood RNA - naive B-cell [nTPM]":"87.5","Blood RNA - naive CD4 T-cell [nTPM]":"40.3","Blood RNA - naive CD8 T-cell [nTPM]":"33.8","Blood RNA - neutrophil [nTPM]":"82.2","Blood RNA - NK-cell [nTPM]":"30.9","Blood RNA - non-classical monocyte [nTPM]":"94.6","Blood RNA - plasmacytoid DC [nTPM]":"99.1","Blood RNA - T-reg [nTPM]":"43.3","Blood RNA - total PBMC [nTPM]":"78.6","Brain RNA - amygdala [nTPM]":"32.7","Brain RNA - basal ganglia [nTPM]":"33.4","Brain RNA - cerebellum [nTPM]":"33.2","Brain RNA - cerebral cortex [nTPM]":"42.1","Brain RNA - hippocampal formation [nTPM]":"33.0","Brain RNA - hypothalamus [nTPM]":"32.7","Brain RNA - medulla oblongata [nTPM]":"33.0","Brain RNA - midbrain [nTPM]":"34.2","Brain RNA - pons [nTPM]":"34.3","Brain RNA - spinal cord [nTPM]":"33.8","Brain RNA - thalamus [nTPM]":"33.5","Brain RNA - white matter [nTPM]":"33.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"24.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"22.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.0","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TRIM2","Gene synonym":["CMT2R","KIAA0517","RNF86"],"Ensembl":"ENSG00000109654","Gene description":"Tripartite motif containing 2","Uniprot":["Q9C040"],"Chromosome":"4","Position":"153152163-153339319","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"116.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"1132.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD4 T-cell":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"47.0","SK-MEL-30":"46.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035853","HPA035854"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA035853":"AB_10669533","HPA035854":"AB_10669659"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.58e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"11.8","Tissue RNA - amygdala [nTPM]":"29.5","Tissue RNA - appendix [nTPM]":"4.8","Tissue RNA - basal ganglia [nTPM]":"64.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"38.6","Tissue RNA - cerebral cortex [nTPM]":"46.2","Tissue RNA - cervix [nTPM]":"23.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"21.6","Tissue RNA - duodenum [nTPM]":"17.4","Tissue RNA - endometrium 1 [nTPM]":"9.9","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"12.6","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"48.0","Tissue RNA - hypothalamus [nTPM]":"34.8","Tissue RNA - kidney [nTPM]":"24.2","Tissue RNA - liver [nTPM]":"7.9","Tissue RNA - lung [nTPM]":"7.2","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"40.1","Tissue RNA - midbrain [nTPM]":"33.2","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"21.6","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"56.3","Tissue RNA - prostate [nTPM]":"13.1","Tissue RNA - rectum [nTPM]":"19.3","Tissue RNA - retina [nTPM]":"19.4","Tissue RNA - salivary gland [nTPM]":"42.9","Tissue RNA - seminal vesicle [nTPM]":"13.4","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"17.3","Tissue RNA - smooth muscle [nTPM]":"7.0","Tissue RNA - spinal cord [nTPM]":"35.3","Tissue RNA - spleen [nTPM]":"10.6","Tissue RNA - stomach 1 [nTPM]":"27.4","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"37.9","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"50.6","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"3.9","Tissue RNA - urinary bladder [nTPM]":"12.0","Tissue RNA - vagina [nTPM]":"11.5","Tissue RNA - white matter [nTPM]":"116.2","Cell RNA - A-431 [nTPM]":"10.2","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"47.0","Cell RNA - AN3-CA [nTPM]":"24.2","Cell RNA - ASC diff [nTPM]":"22.0","Cell RNA - ASC TERT1 [nTPM]":"27.2","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"12.7","Cell RNA - BJ hTERT+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.5","Cell RNA - CACO-2 [nTPM]":"4.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"7.7","Cell RNA - fHDF\/TERT166 [nTPM]":"21.7","Cell RNA - GAMG [nTPM]":"8.5","Cell RNA - HaCaT [nTPM]":"6.4","Cell RNA - HAP1 [nTPM]":"24.7","Cell RNA - HBEC3-KT [nTPM]":"4.7","Cell RNA - HBF TERT88 [nTPM]":"3.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"4.6","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"24.7","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"2.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"12.9","Cell RNA - HUVEC TERT2 [nTPM]":"3.4","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"4.9","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"2.4","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"37.4","Cell RNA - OE19 [nTPM]":"27.5","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"9.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"37.0","Cell RNA - RT4 [nTPM]":"11.8","Cell RNA - SCLC-21H [nTPM]":"14.5","Cell RNA - SH-SY5Y [nTPM]":"27.3","Cell RNA - SiHa [nTPM]":"4.4","Cell RNA - SK-BR-3 [nTPM]":"2.7","Cell RNA - SK-MEL-30 [nTPM]":"46.8","Cell RNA - SuSa [nTPM]":"6.9","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"2.8","Cell RNA - U-138 MG [nTPM]":"12.7","Cell RNA - U-2 OS [nTPM]":"3.0","Cell RNA - U-2197 [nTPM]":"10.8","Cell RNA - U-251 MG [nTPM]":"3.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"20.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"20.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"29.5","Brain RNA - basal ganglia [nTPM]":"64.4","Brain RNA - cerebellum [nTPM]":"38.6","Brain RNA - cerebral cortex [nTPM]":"46.2","Brain RNA - hippocampal formation [nTPM]":"48.0","Brain RNA - hypothalamus [nTPM]":"34.8","Brain RNA - medulla oblongata [nTPM]":"40.1","Brain RNA - midbrain [nTPM]":"33.2","Brain RNA - pons [nTPM]":"56.3","Brain RNA - spinal cord [nTPM]":"35.3","Brain RNA - thalamus [nTPM]":"37.9","Brain RNA - white matter [nTPM]":"116.2","Single Cell Type RNA - Adipocytes [nTPM]":"11.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.7","Single Cell Type RNA - Astrocytes [nTPM]":"189.0","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"67.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"82.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"59.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"101.8","Single Cell Type RNA - Ductal cells [nTPM]":"9.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"113.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.3","Single Cell Type RNA - Endothelial cells [nTPM]":"17.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"62.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"266.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"22.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"95.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"12.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.4","Single Cell Type RNA - Horizontal cells [nTPM]":"111.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"211.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"64.1","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"29.5","Single Cell Type RNA - Macrophages [nTPM]":"2.2","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"86.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"237.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1132.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.5","Single Cell Type RNA - Paneth cells [nTPM]":"41.4","Single Cell Type RNA - Peritubular cells [nTPM]":"32.7","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"62.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"106.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"8.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"90.8","Single Cell Type RNA - Urothelial cells [nTPM]":"33.7"},{"Gene":"TRIOBP","Gene synonym":["DFNB28","HRIHFB2122","KIAA1662","TAP68","Tara"],"Ensembl":"ENSG00000100106","Gene description":"TRIO and F-actin binding protein","Uniprot":["Q9H2D6"],"Chromosome":"22","Position":"37697048-37776556","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Actin-binding"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003747","HPA019769"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003747":"AB_1858328","HPA019769":"AB_1858329"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.29e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"56.3","Tissue RNA - adrenal gland [nTPM]":"46.5","Tissue RNA - amygdala [nTPM]":"15.4","Tissue RNA - appendix [nTPM]":"27.3","Tissue RNA - basal ganglia [nTPM]":"16.6","Tissue RNA - bone marrow [nTPM]":"25.7","Tissue RNA - breast [nTPM]":"50.8","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"14.9","Tissue RNA - cervix [nTPM]":"73.1","Tissue RNA - choroid plexus [nTPM]":"22.1","Tissue RNA - colon [nTPM]":"70.6","Tissue RNA - duodenum [nTPM]":"23.9","Tissue RNA - endometrium 1 [nTPM]":"71.8","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"78.5","Tissue RNA - fallopian tube [nTPM]":"66.1","Tissue RNA - gallbladder [nTPM]":"27.8","Tissue RNA - heart muscle [nTPM]":"74.6","Tissue RNA - hippocampal formation [nTPM]":"12.8","Tissue RNA - hypothalamus [nTPM]":"13.2","Tissue RNA - kidney [nTPM]":"37.2","Tissue RNA - liver [nTPM]":"21.6","Tissue RNA - lung [nTPM]":"51.6","Tissue RNA - lymph node [nTPM]":"17.4","Tissue RNA - medulla oblongata [nTPM]":"20.0","Tissue RNA - midbrain [nTPM]":"17.2","Tissue RNA - ovary [nTPM]":"55.7","Tissue RNA - pancreas [nTPM]":"32.7","Tissue RNA - parathyroid gland [nTPM]":"31.1","Tissue RNA - pituitary gland [nTPM]":"16.9","Tissue RNA - placenta [nTPM]":"44.2","Tissue RNA - pons [nTPM]":"16.5","Tissue RNA - prostate [nTPM]":"45.3","Tissue RNA - rectum [nTPM]":"17.0","Tissue RNA - retina [nTPM]":"4.8","Tissue RNA - salivary gland [nTPM]":"44.3","Tissue RNA - seminal vesicle [nTPM]":"33.3","Tissue RNA - skeletal muscle [nTPM]":"24.3","Tissue RNA - skin 1 [nTPM]":"32.0","Tissue RNA - small intestine [nTPM]":"38.0","Tissue RNA - smooth muscle [nTPM]":"31.0","Tissue RNA - spinal cord [nTPM]":"16.6","Tissue RNA - spleen [nTPM]":"53.1","Tissue RNA - stomach 1 [nTPM]":"53.6","Tissue RNA - testis [nTPM]":"26.1","Tissue RNA - thalamus [nTPM]":"16.9","Tissue RNA - thymus [nTPM]":"16.7","Tissue RNA - thyroid gland [nTPM]":"48.2","Tissue RNA - tongue [nTPM]":"14.3","Tissue RNA - tonsil [nTPM]":"12.5","Tissue RNA - urinary bladder [nTPM]":"66.5","Tissue RNA - vagina [nTPM]":"65.7","Tissue RNA - white matter [nTPM]":"17.3","Cell RNA - A-431 [nTPM]":"65.9","Cell RNA - A549 [nTPM]":"53.1","Cell RNA - AF22 [nTPM]":"33.2","Cell RNA - AN3-CA [nTPM]":"26.4","Cell RNA - ASC diff [nTPM]":"73.1","Cell RNA - ASC TERT1 [nTPM]":"118.1","Cell RNA - BEWO [nTPM]":"47.5","Cell RNA - BJ [nTPM]":"113.0","Cell RNA - BJ hTERT+ [nTPM]":"111.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"57.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.1","Cell RNA - CACO-2 [nTPM]":"11.8","Cell RNA - CAPAN-2 [nTPM]":"44.8","Cell RNA - Daudi [nTPM]":"24.5","Cell RNA - EFO-21 [nTPM]":"30.4","Cell RNA - fHDF\/TERT166 [nTPM]":"69.6","Cell RNA - GAMG [nTPM]":"31.6","Cell RNA - HaCaT [nTPM]":"52.7","Cell RNA - HAP1 [nTPM]":"9.2","Cell RNA - HBEC3-KT [nTPM]":"63.7","Cell RNA - HBF TERT88 [nTPM]":"18.1","Cell RNA - HDLM-2 [nTPM]":"39.6","Cell RNA - HEK 293 [nTPM]":"29.1","Cell RNA - HEL [nTPM]":"6.8","Cell RNA - HeLa [nTPM]":"41.6","Cell RNA - Hep G2 [nTPM]":"22.4","Cell RNA - HHSteC [nTPM]":"75.5","Cell RNA - HL-60 [nTPM]":"32.1","Cell RNA - HMC-1 [nTPM]":"28.9","Cell RNA - HSkMC [nTPM]":"47.1","Cell RNA - hTCEpi [nTPM]":"29.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"52.0","Cell RNA - hTERT-HME1 [nTPM]":"24.5","Cell RNA - hTERT-RPE1 [nTPM]":"125.3","Cell RNA - HUVEC TERT2 [nTPM]":"71.9","Cell RNA - JURKAT [nTPM]":"20.6","Cell RNA - K-562 [nTPM]":"6.4","Cell RNA - Karpas-707 [nTPM]":"34.6","Cell RNA - LHCN-M2 [nTPM]":"45.5","Cell RNA - MCF7 [nTPM]":"39.3","Cell RNA - MOLT-4 [nTPM]":"14.4","Cell RNA - NB-4 [nTPM]":"23.1","Cell RNA - NTERA-2 [nTPM]":"20.2","Cell RNA - OE19 [nTPM]":"65.4","Cell RNA - PC-3 [nTPM]":"63.2","Cell RNA - REH [nTPM]":"25.1","Cell RNA - RH-30 [nTPM]":"23.9","Cell RNA - RPMI-8226 [nTPM]":"17.2","Cell RNA - RPTEC TERT1 [nTPM]":"41.0","Cell RNA - RT4 [nTPM]":"52.8","Cell RNA - SCLC-21H [nTPM]":"16.2","Cell RNA - SH-SY5Y [nTPM]":"25.4","Cell RNA - SiHa [nTPM]":"50.9","Cell RNA - SK-BR-3 [nTPM]":"46.5","Cell RNA - SK-MEL-30 [nTPM]":"59.7","Cell RNA - SuSa [nTPM]":"32.8","Cell RNA - T-47d [nTPM]":"25.4","Cell RNA - THP-1 [nTPM]":"23.0","Cell RNA - TIME [nTPM]":"151.9","Cell RNA - U-138 MG [nTPM]":"87.2","Cell RNA - U-2 OS [nTPM]":"38.6","Cell RNA - U-2197 [nTPM]":"60.6","Cell RNA - U-251 MG [nTPM]":"27.0","Cell RNA - U-266\/70 [nTPM]":"30.4","Cell RNA - U-266\/84 [nTPM]":"9.1","Cell RNA - U-698 [nTPM]":"15.4","Cell RNA - U-87 MG [nTPM]":"82.7","Cell RNA - U-937 [nTPM]":"13.0","Cell RNA - WM-115 [nTPM]":"104.3","Blood RNA - basophil [nTPM]":"7.7","Blood RNA - classical monocyte [nTPM]":"7.6","Blood RNA - eosinophil [nTPM]":"12.2","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"7.5","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"4.1","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"18.2","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"12.5","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"15.4","Brain RNA - basal ganglia [nTPM]":"16.6","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"14.9","Brain RNA - hippocampal formation [nTPM]":"12.8","Brain RNA - hypothalamus [nTPM]":"13.2","Brain RNA - medulla oblongata [nTPM]":"20.0","Brain RNA - midbrain [nTPM]":"17.2","Brain RNA - pons [nTPM]":"16.5","Brain RNA - spinal cord [nTPM]":"16.6","Brain RNA - thalamus [nTPM]":"16.9","Brain RNA - white matter [nTPM]":"17.3","Single Cell Type RNA - Adipocytes [nTPM]":"102.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.7","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"10.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"65.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"62.9","Single Cell Type RNA - Club cells [nTPM]":"23.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"105.7","Single Cell Type RNA - dendritic cells [nTPM]":"14.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"63.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"42.7","Single Cell Type RNA - Early spermatids [nTPM]":"30.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"107.0","Single Cell Type RNA - Endothelial cells [nTPM]":"91.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.9","Single Cell Type RNA - Erythroid cells [nTPM]":"28.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"51.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.2","Single Cell Type RNA - Fibroblasts [nTPM]":"65.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"58.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.2","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"128.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"124.6","Single Cell Type RNA - Hepatocytes [nTPM]":"17.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.7","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"52.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"56.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"10.6","Single Cell Type RNA - Leydig cells [nTPM]":"113.1","Single Cell Type RNA - Macrophages [nTPM]":"31.2","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"32.0","Single Cell Type RNA - Muller glia cells [nTPM]":"29.6","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"62.8","Single Cell Type RNA - Paneth cells [nTPM]":"46.9","Single Cell Type RNA - Peritubular cells [nTPM]":"92.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"41.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.8","Single Cell Type RNA - Spermatocytes [nTPM]":"49.8","Single Cell Type RNA - Spermatogonia [nTPM]":"23.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"57.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"116.0","Single Cell Type RNA - T-cells [nTPM]":"12.7","Single Cell Type RNA - Theca cells [nTPM]":"22.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.6","Single Cell Type RNA - Urothelial cells [nTPM]":"57.9"},{"Gene":"TRPC3","Gene synonym":[],"Ensembl":"ENSG00000138741","Gene description":"Transient receptor potential cation channel subfamily C member 3","Uniprot":["Q13507"],"Chromosome":"4","Position":"121874481-121952060","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.4","pituitary gland":"7.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"18.1","Inhibitory neurons":"82.7","Oligodendrocyte precursor cells":"33.7","Rod photoreceptor cells":"32.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"2.3","Karpas-707":"2.6","U-2 OS":"1.5","U-251 MG":"1.5"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"57.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"4.6","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"7.4","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"2.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"2.6","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"1.2","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"4.6","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"TRPM1","Gene synonym":["CSNB1C","LTRPC1","MLSN1"],"Ensembl":"ENSG00000134160","Gene description":"Transient receptor potential cation channel subfamily M member 1","Uniprot":["Q7Z4N2"],"Chromosome":"15","Position":"31001061-31161273","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"9.4","skin 1":"4.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"627.4","Melanocytes":"158.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"179","RNA cancer specific FPKM":{"melanoma":"14.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"112","RNA cell line specific nTPM":{"SK-MEL-30":"12.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014779","HPA071139"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"HPA014779":"AB_2669090","HPA071139":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"9.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"12.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"627.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"50.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"158.3","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"TRPM7","Gene synonym":["CHAK1","LTRPC7","TRP-PLIK"],"Ensembl":"ENSG00000092439","Gene description":"Transient receptor potential cation channel subfamily M member 7","Uniprot":["Q96QT4"],"Chromosome":"15","Position":"50552473-50686797","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Necrosis","Transport"],"Molecular function":["Calcium channel","Ion channel","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Amyotrophic lateral sclerosis","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"108.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"122.2","Oligodendrocytes":"109.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"122.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035522","HPA052173"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA035522":null,"HPA052173":"AB_2681749"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.5","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"13.3","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"21.4","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"15.4","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"10.3","Tissue RNA - choroid plexus [nTPM]":"29.3","Tissue RNA - colon [nTPM]":"13.8","Tissue RNA - duodenum [nTPM]":"14.4","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"14.6","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"11.1","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"22.9","Tissue RNA - liver [nTPM]":"25.3","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"16.6","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"16.4","Tissue RNA - pancreas [nTPM]":"12.2","Tissue RNA - parathyroid gland [nTPM]":"108.9","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"13.3","Tissue RNA - pons [nTPM]":"5.9","Tissue RNA - prostate [nTPM]":"10.9","Tissue RNA - rectum [nTPM]":"14.4","Tissue RNA - retina [nTPM]":"10.5","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"10.6","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"16.6","Tissue RNA - small intestine [nTPM]":"13.1","Tissue RNA - smooth muscle [nTPM]":"11.4","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"12.2","Tissue RNA - stomach 1 [nTPM]":"13.6","Tissue RNA - testis [nTPM]":"9.9","Tissue RNA - thalamus [nTPM]":"6.4","Tissue RNA - thymus [nTPM]":"15.5","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"9.1","Tissue RNA - tonsil [nTPM]":"14.4","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"8.1","Tissue RNA - white matter [nTPM]":"10.4","Cell RNA - A-431 [nTPM]":"21.4","Cell RNA - A549 [nTPM]":"21.0","Cell RNA - AF22 [nTPM]":"17.2","Cell RNA - AN3-CA [nTPM]":"19.1","Cell RNA - ASC diff [nTPM]":"48.5","Cell RNA - ASC TERT1 [nTPM]":"36.2","Cell RNA - BEWO [nTPM]":"20.9","Cell RNA - BJ [nTPM]":"26.4","Cell RNA - BJ hTERT+ [nTPM]":"36.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.6","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"11.6","Cell RNA - Daudi [nTPM]":"46.4","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"30.8","Cell RNA - GAMG [nTPM]":"42.5","Cell RNA - HaCaT [nTPM]":"35.1","Cell RNA - HAP1 [nTPM]":"23.3","Cell RNA - HBEC3-KT [nTPM]":"19.5","Cell RNA - HBF TERT88 [nTPM]":"23.4","Cell RNA - HDLM-2 [nTPM]":"26.0","Cell RNA - HEK 293 [nTPM]":"13.7","Cell RNA - HEL [nTPM]":"37.1","Cell RNA - HeLa [nTPM]":"31.5","Cell RNA - Hep G2 [nTPM]":"15.4","Cell RNA - HHSteC [nTPM]":"44.0","Cell RNA - HL-60 [nTPM]":"38.8","Cell RNA - HMC-1 [nTPM]":"27.6","Cell RNA - HSkMC [nTPM]":"33.9","Cell RNA - hTCEpi [nTPM]":"22.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.8","Cell RNA - hTERT-HME1 [nTPM]":"35.0","Cell RNA - hTERT-RPE1 [nTPM]":"24.0","Cell RNA - HUVEC TERT2 [nTPM]":"13.5","Cell RNA - JURKAT [nTPM]":"28.8","Cell RNA - K-562 [nTPM]":"42.6","Cell RNA - Karpas-707 [nTPM]":"34.5","Cell RNA - LHCN-M2 [nTPM]":"30.4","Cell RNA - MCF7 [nTPM]":"33.7","Cell RNA - MOLT-4 [nTPM]":"25.1","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"29.4","Cell RNA - PC-3 [nTPM]":"12.8","Cell RNA - REH [nTPM]":"27.2","Cell RNA - RH-30 [nTPM]":"23.7","Cell RNA - RPMI-8226 [nTPM]":"22.7","Cell RNA - RPTEC TERT1 [nTPM]":"23.0","Cell RNA - RT4 [nTPM]":"49.9","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"18.1","Cell RNA - SiHa [nTPM]":"18.2","Cell RNA - SK-BR-3 [nTPM]":"28.7","Cell RNA - SK-MEL-30 [nTPM]":"35.8","Cell RNA - SuSa [nTPM]":"30.1","Cell RNA - T-47d [nTPM]":"18.0","Cell RNA - THP-1 [nTPM]":"41.6","Cell RNA - TIME [nTPM]":"20.7","Cell RNA - U-138 MG [nTPM]":"26.1","Cell RNA - U-2 OS [nTPM]":"12.4","Cell RNA - U-2197 [nTPM]":"122.4","Cell RNA - U-251 MG [nTPM]":"30.8","Cell RNA - U-266\/70 [nTPM]":"23.3","Cell RNA - U-266\/84 [nTPM]":"54.9","Cell RNA - U-698 [nTPM]":"44.0","Cell RNA - U-87 MG [nTPM]":"28.4","Cell RNA - U-937 [nTPM]":"77.5","Cell RNA - WM-115 [nTPM]":"24.8","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"15.4","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"5.9","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"6.4","Brain RNA - white matter [nTPM]":"10.4","Single Cell Type RNA - Adipocytes [nTPM]":"23.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.3","Single Cell Type RNA - Astrocytes [nTPM]":"73.1","Single Cell Type RNA - B-cells [nTPM]":"36.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.9","Single Cell Type RNA - Bipolar cells [nTPM]":"21.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.0","Single Cell Type RNA - dendritic cells [nTPM]":"38.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"33.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.1","Single Cell Type RNA - Endothelial cells [nTPM]":"19.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.5","Single Cell Type RNA - Erythroid cells [nTPM]":"29.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"122.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.4","Single Cell Type RNA - Fibroblasts [nTPM]":"26.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.1","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"26.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"43.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.6","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"92.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"22.4","Single Cell Type RNA - Langerhans cells [nTPM]":"19.8","Single Cell Type RNA - Late spermatids [nTPM]":"26.0","Single Cell Type RNA - Leydig cells [nTPM]":"26.4","Single Cell Type RNA - Macrophages [nTPM]":"26.5","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"66.5","Single Cell Type RNA - monocytes [nTPM]":"24.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.5","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"80.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"109.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.5","Single Cell Type RNA - Paneth cells [nTPM]":"13.9","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.0","Single Cell Type RNA - Spermatocytes [nTPM]":"23.1","Single Cell Type RNA - Spermatogonia [nTPM]":"23.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"34.5","Single Cell Type RNA - Theca cells [nTPM]":"22.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.4","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"},{"Gene":"TRPV4","Gene synonym":["CMT2C","OTRPC4","TRP12","VR-OAC","VRL-2","VROAC"],"Ensembl":"ENSG00000111199","Gene description":"Transient receptor potential cation channel subfamily V member 4","Uniprot":["Q9HBA0"],"Chromosome":"12","Position":"109783087-109833406","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Dwarfism","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"50.8","salivary gland":"19.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"17.1","Cholangiocytes":"20.0","Cytotrophoblasts":"20.0","Kupffer cells":"19.6","Respiratory ciliated cells":"28.2","Syncytiotrophoblasts":"21.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"hippocampal formation":"4.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"7.9","BJ hTERT+":"9.5","EFO-21":"7.2","HaCaT":"14.2","HUVEC TERT2":"8.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007150"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007150":"AB_1080393"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.10e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"50.8","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"4.7","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"14.7","Tissue RNA - liver [nTPM]":"8.6","Tissue RNA - lung [nTPM]":"2.2","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"5.2","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"19.2","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"1.8","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"2.4","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.0","Cell RNA - ASC TERT1 [nTPM]":"1.2","Cell RNA - BEWO [nTPM]":"7.9","Cell RNA - BJ [nTPM]":"4.2","Cell RNA - BJ hTERT+ [nTPM]":"9.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"7.2","Cell RNA - fHDF\/TERT166 [nTPM]":"5.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"14.2","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"3.7","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"3.4","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.7","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"8.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"5.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"4.9","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"2.6","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"1.1","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.6","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"12.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"19.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"2.6","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"TRRAP","Gene synonym":["PAF400","TR-AP","Tra1"],"Ensembl":"ENSG00000196367","Gene description":"Transformation\/transcription domain associated protein","Uniprot":["Q9Y4A5"],"Chromosome":"7","Position":"98877933-99050831","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Deafness","Disease variant","Mental retardation","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054376"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA054376":"AB_2682467"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.77e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.0","Tissue RNA - adrenal gland [nTPM]":"8.1","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"7.4","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"11.1","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"10.3","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"8.3","Tissue RNA - choroid plexus [nTPM]":"5.9","Tissue RNA - colon [nTPM]":"7.7","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"6.8","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"4.9","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"6.7","Tissue RNA - lung [nTPM]":"7.0","Tissue RNA - lymph node [nTPM]":"9.3","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"10.9","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"10.3","Tissue RNA - pituitary gland [nTPM]":"14.0","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"7.1","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"7.6","Tissue RNA - skin 1 [nTPM]":"11.2","Tissue RNA - small intestine [nTPM]":"8.4","Tissue RNA - smooth muscle [nTPM]":"6.2","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"8.5","Tissue RNA - stomach 1 [nTPM]":"7.1","Tissue RNA - testis [nTPM]":"11.0","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"15.8","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"24.0","Cell RNA - A549 [nTPM]":"27.2","Cell RNA - AF22 [nTPM]":"27.7","Cell RNA - AN3-CA [nTPM]":"23.4","Cell RNA - ASC diff [nTPM]":"12.9","Cell RNA - ASC TERT1 [nTPM]":"13.8","Cell RNA - BEWO [nTPM]":"13.7","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"13.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.1","Cell RNA - CACO-2 [nTPM]":"21.2","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"32.8","Cell RNA - EFO-21 [nTPM]":"15.9","Cell RNA - fHDF\/TERT166 [nTPM]":"19.1","Cell RNA - GAMG [nTPM]":"30.3","Cell RNA - HaCaT [nTPM]":"12.2","Cell RNA - HAP1 [nTPM]":"29.1","Cell RNA - HBEC3-KT [nTPM]":"14.0","Cell RNA - HBF TERT88 [nTPM]":"17.7","Cell RNA - HDLM-2 [nTPM]":"19.2","Cell RNA - HEK 293 [nTPM]":"28.3","Cell RNA - HEL [nTPM]":"20.2","Cell RNA - HeLa [nTPM]":"20.3","Cell RNA - Hep G2 [nTPM]":"11.7","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"36.9","Cell RNA - HMC-1 [nTPM]":"14.3","Cell RNA - HSkMC [nTPM]":"12.6","Cell RNA - hTCEpi [nTPM]":"8.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.8","Cell RNA - hTERT-HME1 [nTPM]":"21.7","Cell RNA - hTERT-RPE1 [nTPM]":"10.9","Cell RNA - HUVEC TERT2 [nTPM]":"20.5","Cell RNA - JURKAT [nTPM]":"29.2","Cell RNA - K-562 [nTPM]":"35.4","Cell RNA - Karpas-707 [nTPM]":"59.8","Cell RNA - LHCN-M2 [nTPM]":"14.8","Cell RNA - MCF7 [nTPM]":"44.0","Cell RNA - MOLT-4 [nTPM]":"45.0","Cell RNA - NB-4 [nTPM]":"13.5","Cell RNA - NTERA-2 [nTPM]":"21.1","Cell RNA - OE19 [nTPM]":"14.1","Cell RNA - PC-3 [nTPM]":"16.6","Cell RNA - REH [nTPM]":"32.7","Cell RNA - RH-30 [nTPM]":"16.0","Cell RNA - RPMI-8226 [nTPM]":"25.2","Cell RNA - RPTEC TERT1 [nTPM]":"7.7","Cell RNA - RT4 [nTPM]":"26.6","Cell RNA - SCLC-21H [nTPM]":"21.6","Cell RNA - SH-SY5Y [nTPM]":"27.1","Cell RNA - SiHa [nTPM]":"26.1","Cell RNA - SK-BR-3 [nTPM]":"16.6","Cell RNA - SK-MEL-30 [nTPM]":"8.4","Cell RNA - SuSa [nTPM]":"22.7","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"15.7","Cell RNA - TIME [nTPM]":"22.0","Cell RNA - U-138 MG [nTPM]":"21.1","Cell RNA - U-2 OS [nTPM]":"30.6","Cell RNA - U-2197 [nTPM]":"28.3","Cell RNA - U-251 MG [nTPM]":"24.2","Cell RNA - U-266\/70 [nTPM]":"24.7","Cell RNA - U-266\/84 [nTPM]":"30.2","Cell RNA - U-698 [nTPM]":"47.8","Cell RNA - U-87 MG [nTPM]":"14.9","Cell RNA - U-937 [nTPM]":"18.3","Cell RNA - WM-115 [nTPM]":"21.3","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"10.3","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.2","Single Cell Type RNA - Astrocytes [nTPM]":"30.3","Single Cell Type RNA - B-cells [nTPM]":"16.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"15.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"9.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - dendritic cells [nTPM]":"15.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.1","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.6","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.2","Single Cell Type RNA - Fibroblasts [nTPM]":"11.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.1","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"26.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"11.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.0","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.4","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"12.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"9.8","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.3","Single Cell Type RNA - Paneth cells [nTPM]":"5.8","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"25.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.4","Single Cell Type RNA - Spermatocytes [nTPM]":"14.8","Single Cell Type RNA - Spermatogonia [nTPM]":"8.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"17.1","Single Cell Type RNA - Theca cells [nTPM]":"12.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.1","Single Cell Type RNA - Urothelial cells [nTPM]":"7.5"},{"Gene":"TSC1","Gene synonym":["hamartin","KIAA0243","LAM","TSC"],"Ensembl":"ENSG00000165699","Gene description":"TSC complex subunit 1","Uniprot":["Q92574"],"Chromosome":"9","Position":"132891348-132946874","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"133.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011568","CAB012481","HPA074132"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB011568":"AB_732752","CAB012481":null,"HPA074132":"AB_2686666"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"14.5","Tissue RNA - amygdala [nTPM]":"6.1","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"12.2","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"13.4","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"12.0","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"14.0","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"13.1","Tissue RNA - liver [nTPM]":"10.9","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"18.2","Tissue RNA - pancreas [nTPM]":"12.8","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"16.2","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"4.9","Tissue RNA - prostate [nTPM]":"13.1","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"14.9","Tissue RNA - skin 1 [nTPM]":"15.8","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"12.2","Tissue RNA - testis [nTPM]":"22.8","Tissue RNA - thalamus [nTPM]":"4.5","Tissue RNA - thymus [nTPM]":"6.7","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"14.6","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"12.7","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"8.3","Cell RNA - A549 [nTPM]":"9.7","Cell RNA - AF22 [nTPM]":"13.0","Cell RNA - AN3-CA [nTPM]":"10.7","Cell RNA - ASC diff [nTPM]":"13.0","Cell RNA - ASC TERT1 [nTPM]":"12.2","Cell RNA - BEWO [nTPM]":"24.2","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"17.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.0","Cell RNA - CACO-2 [nTPM]":"16.5","Cell RNA - CAPAN-2 [nTPM]":"9.5","Cell RNA - Daudi [nTPM]":"19.4","Cell RNA - EFO-21 [nTPM]":"4.7","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"17.0","Cell RNA - HaCaT [nTPM]":"21.0","Cell RNA - HAP1 [nTPM]":"15.4","Cell RNA - HBEC3-KT [nTPM]":"11.0","Cell RNA - HBF TERT88 [nTPM]":"11.3","Cell RNA - HDLM-2 [nTPM]":"9.4","Cell RNA - HEK 293 [nTPM]":"8.2","Cell RNA - HEL [nTPM]":"6.1","Cell RNA - HeLa [nTPM]":"19.9","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"15.6","Cell RNA - HL-60 [nTPM]":"9.4","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"13.6","Cell RNA - hTCEpi [nTPM]":"8.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.3","Cell RNA - hTERT-HME1 [nTPM]":"17.4","Cell RNA - hTERT-RPE1 [nTPM]":"11.1","Cell RNA - HUVEC TERT2 [nTPM]":"13.0","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"11.1","Cell RNA - Karpas-707 [nTPM]":"10.2","Cell RNA - LHCN-M2 [nTPM]":"12.9","Cell RNA - MCF7 [nTPM]":"15.4","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"17.8","Cell RNA - OE19 [nTPM]":"12.1","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"24.5","Cell RNA - RPMI-8226 [nTPM]":"11.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"10.7","Cell RNA - SCLC-21H [nTPM]":"6.4","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"12.7","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"6.2","Cell RNA - SuSa [nTPM]":"15.2","Cell RNA - T-47d [nTPM]":"14.4","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"13.8","Cell RNA - U-138 MG [nTPM]":"18.1","Cell RNA - U-2 OS [nTPM]":"10.8","Cell RNA - U-2197 [nTPM]":"11.4","Cell RNA - U-251 MG [nTPM]":"7.7","Cell RNA - U-266\/70 [nTPM]":"5.7","Cell RNA - U-266\/84 [nTPM]":"13.8","Cell RNA - U-698 [nTPM]":"18.5","Cell RNA - U-87 MG [nTPM]":"10.3","Cell RNA - U-937 [nTPM]":"5.2","Cell RNA - WM-115 [nTPM]":"8.2","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"3.8","Blood RNA - MAIT T-cell [nTPM]":"3.5","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"6.1","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"4.9","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"4.5","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.2","Single Cell Type RNA - Astrocytes [nTPM]":"35.3","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"26.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"13.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"45.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.2","Single Cell Type RNA - Endothelial cells [nTPM]":"12.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.0","Single Cell Type RNA - Fibroblasts [nTPM]":"14.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.8","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"27.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"5.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.9","Single Cell Type RNA - Late spermatids [nTPM]":"133.1","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"10.8","Single Cell Type RNA - Muller glia cells [nTPM]":"9.7","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.5","Single Cell Type RNA - Paneth cells [nTPM]":"7.9","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.4","Single Cell Type RNA - Spermatocytes [nTPM]":"22.4","Single Cell Type RNA - Spermatogonia [nTPM]":"20.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - T-cells [nTPM]":"11.9","Single Cell Type RNA - Theca cells [nTPM]":"23.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.6","Single Cell Type RNA - Urothelial cells [nTPM]":"11.0"},{"Gene":"TSC2","Gene synonym":["LAM","PPP1R160","TSC4","tuberin"],"Ensembl":"ENSG00000103197","Gene description":"TSC complex subunit 2","Uniprot":["P49815"],"Chromosome":"16","Position":"2047967-2089491","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002225","HPA030409","HPA049679"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002225":"AB_564043","HPA030409":"AB_10602483","HPA049679":"AB_2680848"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.06e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.6","Tissue RNA - adrenal gland [nTPM]":"10.0","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"10.9","Tissue RNA - breast [nTPM]":"12.6","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"6.1","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"15.3","Tissue RNA - duodenum [nTPM]":"12.4","Tissue RNA - endometrium 1 [nTPM]":"17.4","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"12.6","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"12.0","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"3.1","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"18.4","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"14.7","Tissue RNA - pituitary gland [nTPM]":"16.5","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"12.4","Tissue RNA - rectum [nTPM]":"9.1","Tissue RNA - retina [nTPM]":"17.7","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"31.1","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"11.4","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"15.7","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"18.6","Tissue RNA - tongue [nTPM]":"14.5","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"14.0","Tissue RNA - vagina [nTPM]":"12.8","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"13.5","Cell RNA - A549 [nTPM]":"21.4","Cell RNA - AF22 [nTPM]":"28.9","Cell RNA - AN3-CA [nTPM]":"32.5","Cell RNA - ASC diff [nTPM]":"33.7","Cell RNA - ASC TERT1 [nTPM]":"28.1","Cell RNA - BEWO [nTPM]":"24.3","Cell RNA - BJ [nTPM]":"31.7","Cell RNA - BJ hTERT+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.7","Cell RNA - CACO-2 [nTPM]":"25.7","Cell RNA - CAPAN-2 [nTPM]":"25.4","Cell RNA - Daudi [nTPM]":"20.5","Cell RNA - EFO-21 [nTPM]":"27.6","Cell RNA - fHDF\/TERT166 [nTPM]":"26.2","Cell RNA - GAMG [nTPM]":"11.0","Cell RNA - HaCaT [nTPM]":"22.0","Cell RNA - HAP1 [nTPM]":"17.5","Cell RNA - HBEC3-KT [nTPM]":"23.1","Cell RNA - HBF TERT88 [nTPM]":"17.3","Cell RNA - HDLM-2 [nTPM]":"15.5","Cell RNA - HEK 293 [nTPM]":"28.5","Cell RNA - HEL [nTPM]":"19.2","Cell RNA - HeLa [nTPM]":"39.6","Cell RNA - Hep G2 [nTPM]":"10.7","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"24.0","Cell RNA - HMC-1 [nTPM]":"22.4","Cell RNA - HSkMC [nTPM]":"33.5","Cell RNA - hTCEpi [nTPM]":"14.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.9","Cell RNA - hTERT-HME1 [nTPM]":"13.9","Cell RNA - hTERT-RPE1 [nTPM]":"27.9","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"14.4","Cell RNA - K-562 [nTPM]":"19.0","Cell RNA - Karpas-707 [nTPM]":"17.7","Cell RNA - LHCN-M2 [nTPM]":"21.0","Cell RNA - MCF7 [nTPM]":"27.0","Cell RNA - MOLT-4 [nTPM]":"28.9","Cell RNA - NB-4 [nTPM]":"7.1","Cell RNA - NTERA-2 [nTPM]":"29.8","Cell RNA - OE19 [nTPM]":"10.1","Cell RNA - PC-3 [nTPM]":"21.2","Cell RNA - REH [nTPM]":"45.3","Cell RNA - RH-30 [nTPM]":"31.6","Cell RNA - RPMI-8226 [nTPM]":"25.7","Cell RNA - RPTEC TERT1 [nTPM]":"9.4","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"22.1","Cell RNA - SH-SY5Y [nTPM]":"41.3","Cell RNA - SiHa [nTPM]":"45.2","Cell RNA - SK-BR-3 [nTPM]":"29.4","Cell RNA - SK-MEL-30 [nTPM]":"15.3","Cell RNA - SuSa [nTPM]":"28.2","Cell RNA - T-47d [nTPM]":"26.8","Cell RNA - THP-1 [nTPM]":"17.5","Cell RNA - TIME [nTPM]":"35.5","Cell RNA - U-138 MG [nTPM]":"24.5","Cell RNA - U-2 OS [nTPM]":"16.5","Cell RNA - U-2197 [nTPM]":"22.0","Cell RNA - U-251 MG [nTPM]":"16.5","Cell RNA - U-266\/70 [nTPM]":"39.0","Cell RNA - U-266\/84 [nTPM]":"42.7","Cell RNA - U-698 [nTPM]":"40.8","Cell RNA - U-87 MG [nTPM]":"10.2","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"29.6","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"6.1","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"3.1","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"23.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.9","Single Cell Type RNA - Astrocytes [nTPM]":"43.8","Single Cell Type RNA - B-cells [nTPM]":"16.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"53.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"15.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"93.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.0","Single Cell Type RNA - dendritic cells [nTPM]":"17.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.2","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.3","Single Cell Type RNA - Endothelial cells [nTPM]":"25.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"32.5","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.0","Single Cell Type RNA - Fibroblasts [nTPM]":"19.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.1","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"49.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"38.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.4","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.6","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"29.3","Single Cell Type RNA - Leydig cells [nTPM]":"28.3","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"12.1","Single Cell Type RNA - Muller glia cells [nTPM]":"19.0","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.4","Single Cell Type RNA - Paneth cells [nTPM]":"17.5","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"64.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.4","Single Cell Type RNA - Spermatocytes [nTPM]":"18.3","Single Cell Type RNA - Spermatogonia [nTPM]":"37.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"18.8","Single Cell Type RNA - Theca cells [nTPM]":"31.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.9","Single Cell Type RNA - Urothelial cells [nTPM]":"10.6"},{"Gene":"TSPAN12","Gene synonym":["NET-2","TM4SF12"],"Ensembl":"ENSG00000106025","Gene description":"Tetraspanin 12","Uniprot":["O95859"],"Chromosome":"7","Position":"120787320-120858402","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"91.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"118.6","Collecting duct cells":"103.0","Distal tubular cells":"189.8","Glandular and luminal cells":"87.5","Proximal tubular cells":"111.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"44.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"53.0","HUVEC TERT2":"58.3","RH-30":"52.2","RPTEC TERT1":"90.5","RT4":"65.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051570","HPA058244"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Microtubules"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA051570":null,"HPA058244":"AB_2683652"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"65.9","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"8.7","Tissue RNA - cerebellum [nTPM]":"5.2","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"21.4","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"24.0","Tissue RNA - duodenum [nTPM]":"39.4","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"14.9","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"10.9","Tissue RNA - gallbladder [nTPM]":"20.4","Tissue RNA - heart muscle [nTPM]":"47.7","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"91.6","Tissue RNA - liver [nTPM]":"35.8","Tissue RNA - lung [nTPM]":"45.8","Tissue RNA - lymph node [nTPM]":"4.5","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"17.4","Tissue RNA - parathyroid gland [nTPM]":"10.7","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"20.3","Tissue RNA - pons [nTPM]":"5.2","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"20.4","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"46.8","Tissue RNA - seminal vesicle [nTPM]":"22.4","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"42.0","Tissue RNA - smooth muscle [nTPM]":"11.9","Tissue RNA - spinal cord [nTPM]":"4.6","Tissue RNA - spleen [nTPM]":"28.2","Tissue RNA - stomach 1 [nTPM]":"22.1","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"23.4","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"17.5","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.4","Cell RNA - AF22 [nTPM]":"15.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"3.1","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"14.7","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"2.5","Cell RNA - CAPAN-2 [nTPM]":"4.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"10.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"1.8","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"7.7","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"1.9","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"53.0","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"14.5","Cell RNA - Hep G2 [nTPM]":"2.2","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"58.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"6.8","Cell RNA - MCF7 [nTPM]":"2.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"24.5","Cell RNA - OE19 [nTPM]":"11.1","Cell RNA - PC-3 [nTPM]":"9.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"52.2","Cell RNA - RPMI-8226 [nTPM]":"2.0","Cell RNA - RPTEC TERT1 [nTPM]":"90.5","Cell RNA - RT4 [nTPM]":"65.4","Cell RNA - SCLC-21H [nTPM]":"12.5","Cell RNA - SH-SY5Y [nTPM]":"7.4","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"20.0","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"2.5","Cell RNA - U-138 MG [nTPM]":"12.3","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"6.5","Cell RNA - U-266\/70 [nTPM]":"15.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"5.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"5.2","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"5.2","Brain RNA - spinal cord [nTPM]":"4.6","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"40.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"118.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.0","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"1.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"62.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"19.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"103.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"189.8","Single Cell Type RNA - Ductal cells [nTPM]":"6.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"63.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"38.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"53.5","Single Cell Type RNA - Fibroblasts [nTPM]":"10.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"87.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"32.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"30.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"2.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"68.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"111.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"8.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.2","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"9.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.5","Single Cell Type RNA - Urothelial cells [nTPM]":"28.3"},{"Gene":"TSPEAR","Gene synonym":["C21orf29","DFNB98","MGC11251","TSP-EAR"],"Ensembl":"ENSG00000175894","Gene description":"Thrombospondin type laminin G domain and EAR repeats","Uniprot":["Q8WU66"],"Chromosome":"21","Position":"44497893-44711572","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Ectodermal dysplasia","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"1.0","testis":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1.3","Early spermatids":"3.3","Excitatory neurons":"1.1","Oligodendrocytes":"1.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SH-SY5Y":"1.7","U-2 OS":"1.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"olfactory bulb":"1.0"},"Antibody":["CAB034203","CAB034204","HPA052995"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034203":"AB_1567654","CAB034204":"AB_1567655","HPA052995":"AB_2682008"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TSPYL1","Gene synonym":["TSPYL"],"Ensembl":"ENSG00000189241","Gene description":"TSPY like 1","Uniprot":["Q9H0U9"],"Chromosome":"6","Position":"116267760-116279930","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031970"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA031970":"AB_2674092"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.40e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.48e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.5","Tissue RNA - adrenal gland [nTPM]":"73.8","Tissue RNA - amygdala [nTPM]":"51.1","Tissue RNA - appendix [nTPM]":"17.1","Tissue RNA - basal ganglia [nTPM]":"56.4","Tissue RNA - bone marrow [nTPM]":"34.4","Tissue RNA - breast [nTPM]":"23.4","Tissue RNA - cerebellum [nTPM]":"35.2","Tissue RNA - cerebral cortex [nTPM]":"78.2","Tissue RNA - cervix [nTPM]":"22.5","Tissue RNA - choroid plexus [nTPM]":"25.5","Tissue RNA - colon [nTPM]":"30.8","Tissue RNA - duodenum [nTPM]":"24.4","Tissue RNA - endometrium 1 [nTPM]":"28.4","Tissue RNA - epididymis [nTPM]":"33.0","Tissue RNA - esophagus [nTPM]":"34.0","Tissue RNA - fallopian tube [nTPM]":"31.4","Tissue RNA - gallbladder [nTPM]":"20.5","Tissue RNA - heart muscle [nTPM]":"43.3","Tissue RNA - hippocampal formation [nTPM]":"64.9","Tissue RNA - hypothalamus [nTPM]":"38.1","Tissue RNA - kidney [nTPM]":"50.4","Tissue RNA - liver [nTPM]":"40.9","Tissue RNA - lung [nTPM]":"21.4","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"25.9","Tissue RNA - midbrain [nTPM]":"22.2","Tissue RNA - ovary [nTPM]":"34.9","Tissue RNA - pancreas [nTPM]":"33.3","Tissue RNA - parathyroid gland [nTPM]":"63.9","Tissue RNA - pituitary gland [nTPM]":"40.1","Tissue RNA - placenta [nTPM]":"16.0","Tissue RNA - pons [nTPM]":"26.0","Tissue RNA - prostate [nTPM]":"42.0","Tissue RNA - rectum [nTPM]":"17.7","Tissue RNA - retina [nTPM]":"26.1","Tissue RNA - salivary gland [nTPM]":"30.2","Tissue RNA - seminal vesicle [nTPM]":"33.9","Tissue RNA - skeletal muscle [nTPM]":"114.9","Tissue RNA - skin 1 [nTPM]":"29.4","Tissue RNA - small intestine [nTPM]":"30.0","Tissue RNA - smooth muscle [nTPM]":"24.3","Tissue RNA - spinal cord [nTPM]":"17.1","Tissue RNA - spleen [nTPM]":"29.5","Tissue RNA - stomach 1 [nTPM]":"35.5","Tissue RNA - testis [nTPM]":"28.9","Tissue RNA - thalamus [nTPM]":"34.6","Tissue RNA - thymus [nTPM]":"22.3","Tissue RNA - thyroid gland [nTPM]":"39.6","Tissue RNA - tongue [nTPM]":"91.9","Tissue RNA - tonsil [nTPM]":"25.6","Tissue RNA - urinary bladder [nTPM]":"31.4","Tissue RNA - vagina [nTPM]":"22.7","Tissue RNA - white matter [nTPM]":"44.5","Cell RNA - A-431 [nTPM]":"22.2","Cell RNA - A549 [nTPM]":"21.5","Cell RNA - AF22 [nTPM]":"27.3","Cell RNA - AN3-CA [nTPM]":"50.3","Cell RNA - ASC diff [nTPM]":"47.2","Cell RNA - ASC TERT1 [nTPM]":"30.9","Cell RNA - BEWO [nTPM]":"22.7","Cell RNA - BJ [nTPM]":"35.2","Cell RNA - BJ hTERT+ [nTPM]":"34.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.8","Cell RNA - CACO-2 [nTPM]":"27.7","Cell RNA - CAPAN-2 [nTPM]":"15.9","Cell RNA - Daudi [nTPM]":"47.3","Cell RNA - EFO-21 [nTPM]":"43.0","Cell RNA - fHDF\/TERT166 [nTPM]":"40.8","Cell RNA - GAMG [nTPM]":"28.2","Cell RNA - HaCaT [nTPM]":"38.5","Cell RNA - HAP1 [nTPM]":"21.6","Cell RNA - HBEC3-KT [nTPM]":"59.8","Cell RNA - HBF TERT88 [nTPM]":"33.2","Cell RNA - HDLM-2 [nTPM]":"19.4","Cell RNA - HEK 293 [nTPM]":"56.0","Cell RNA - HEL [nTPM]":"19.1","Cell RNA - HeLa [nTPM]":"29.9","Cell RNA - Hep G2 [nTPM]":"50.8","Cell RNA - HHSteC [nTPM]":"29.8","Cell RNA - HL-60 [nTPM]":"31.9","Cell RNA - HMC-1 [nTPM]":"11.2","Cell RNA - HSkMC [nTPM]":"36.2","Cell RNA - hTCEpi [nTPM]":"46.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.5","Cell RNA - hTERT-HME1 [nTPM]":"31.2","Cell RNA - hTERT-RPE1 [nTPM]":"32.9","Cell RNA - HUVEC TERT2 [nTPM]":"30.3","Cell RNA - JURKAT [nTPM]":"20.7","Cell RNA - K-562 [nTPM]":"34.3","Cell RNA - Karpas-707 [nTPM]":"36.1","Cell RNA - LHCN-M2 [nTPM]":"44.2","Cell RNA - MCF7 [nTPM]":"48.9","Cell RNA - MOLT-4 [nTPM]":"21.5","Cell RNA - NB-4 [nTPM]":"18.9","Cell RNA - NTERA-2 [nTPM]":"13.6","Cell RNA - OE19 [nTPM]":"21.3","Cell RNA - PC-3 [nTPM]":"19.8","Cell RNA - REH [nTPM]":"19.1","Cell RNA - RH-30 [nTPM]":"23.5","Cell RNA - RPMI-8226 [nTPM]":"26.3","Cell RNA - RPTEC TERT1 [nTPM]":"54.9","Cell RNA - RT4 [nTPM]":"42.9","Cell RNA - SCLC-21H [nTPM]":"23.7","Cell RNA - SH-SY5Y [nTPM]":"23.6","Cell RNA - SiHa [nTPM]":"29.2","Cell RNA - SK-BR-3 [nTPM]":"38.8","Cell RNA - SK-MEL-30 [nTPM]":"18.0","Cell RNA - SuSa [nTPM]":"30.6","Cell RNA - T-47d [nTPM]":"51.0","Cell RNA - THP-1 [nTPM]":"39.1","Cell RNA - TIME [nTPM]":"37.3","Cell RNA - U-138 MG [nTPM]":"21.2","Cell RNA - U-2 OS [nTPM]":"18.7","Cell RNA - U-2197 [nTPM]":"17.2","Cell RNA - U-251 MG [nTPM]":"38.7","Cell RNA - U-266\/70 [nTPM]":"19.8","Cell RNA - U-266\/84 [nTPM]":"22.7","Cell RNA - U-698 [nTPM]":"25.2","Cell RNA - U-87 MG [nTPM]":"35.1","Cell RNA - U-937 [nTPM]":"20.3","Cell RNA - WM-115 [nTPM]":"14.1","Blood RNA - basophil [nTPM]":"121.0","Blood RNA - classical monocyte [nTPM]":"30.1","Blood RNA - eosinophil [nTPM]":"51.5","Blood RNA - gdT-cell [nTPM]":"40.5","Blood RNA - intermediate monocyte [nTPM]":"51.0","Blood RNA - MAIT T-cell [nTPM]":"61.4","Blood RNA - memory B-cell [nTPM]":"46.4","Blood RNA - memory CD4 T-cell [nTPM]":"52.4","Blood RNA - memory CD8 T-cell [nTPM]":"45.4","Blood RNA - myeloid DC [nTPM]":"26.1","Blood RNA - naive B-cell [nTPM]":"52.2","Blood RNA - naive CD4 T-cell [nTPM]":"51.1","Blood RNA - naive CD8 T-cell [nTPM]":"50.0","Blood RNA - neutrophil [nTPM]":"24.1","Blood RNA - NK-cell [nTPM]":"33.2","Blood RNA - non-classical monocyte [nTPM]":"57.7","Blood RNA - plasmacytoid DC [nTPM]":"44.9","Blood RNA - T-reg [nTPM]":"44.8","Blood RNA - total PBMC [nTPM]":"34.0","Brain RNA - amygdala [nTPM]":"51.1","Brain RNA - basal ganglia [nTPM]":"56.4","Brain RNA - cerebellum [nTPM]":"35.2","Brain RNA - cerebral cortex [nTPM]":"78.2","Brain RNA - hippocampal formation [nTPM]":"64.9","Brain RNA - hypothalamus [nTPM]":"38.1","Brain RNA - medulla oblongata [nTPM]":"25.9","Brain RNA - midbrain [nTPM]":"22.2","Brain RNA - pons [nTPM]":"26.0","Brain RNA - spinal cord [nTPM]":"17.1","Brain RNA - thalamus [nTPM]":"34.6","Brain RNA - white matter [nTPM]":"44.5","Single Cell Type RNA - Adipocytes [nTPM]":"29.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.9","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"65.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"166.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"100.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"70.6","Single Cell Type RNA - Bipolar cells [nTPM]":"81.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"91.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"47.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"100.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"40.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"104.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"54.8","Single Cell Type RNA - dendritic cells [nTPM]":"54.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"154.6","Single Cell Type RNA - Ductal cells [nTPM]":"40.8","Single Cell Type RNA - Early spermatids [nTPM]":"33.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.0","Single Cell Type RNA - Endothelial cells [nTPM]":"40.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"74.6","Single Cell Type RNA - Erythroid cells [nTPM]":"49.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"65.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.5","Single Cell Type RNA - Fibroblasts [nTPM]":"63.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.9","Single Cell Type RNA - granulocytes [nTPM]":"31.7","Single Cell Type RNA - Granulosa cells [nTPM]":"67.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"73.9","Single Cell Type RNA - Hepatocytes [nTPM]":"81.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.4","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"59.3","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"82.1","Single Cell Type RNA - Langerhans cells [nTPM]":"116.0","Single Cell Type RNA - Late spermatids [nTPM]":"20.2","Single Cell Type RNA - Leydig cells [nTPM]":"75.5","Single Cell Type RNA - Macrophages [nTPM]":"40.2","Single Cell Type RNA - Melanocytes [nTPM]":"87.2","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"38.3","Single Cell Type RNA - Muller glia cells [nTPM]":"82.6","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.8","Single Cell Type RNA - Paneth cells [nTPM]":"52.5","Single Cell Type RNA - Peritubular cells [nTPM]":"95.5","Single Cell Type RNA - Plasma cells [nTPM]":"24.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"77.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"60.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"218.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"41.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.1","Single Cell Type RNA - Sertoli cells [nTPM]":"131.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"87.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"63.5","Single Cell Type RNA - Spermatocytes [nTPM]":"61.9","Single Cell Type RNA - Spermatogonia [nTPM]":"39.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"55.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"162.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.7","Single Cell Type RNA - T-cells [nTPM]":"69.1","Single Cell Type RNA - Theca cells [nTPM]":"101.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"70.2","Single Cell Type RNA - Urothelial cells [nTPM]":"75.8"},{"Gene":"TTBK2","Gene synonym":["KIAA0847","SCA11"],"Ensembl":"ENSG00000128881","Gene description":"Tau tubulin kinase 2","Uniprot":["Q6IQ55"],"Chromosome":"15","Position":"42738730-42920809","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"33.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"153.8","Inhibitory neurons":"185.1","Late spermatids":"146.2","Oligodendrocytes":"125.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018113","HPA049866"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA018113":"AB_1858421","HPA049866":"AB_2680923"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"7.7","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"9.9","Tissue RNA - bone marrow [nTPM]":"5.2","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"11.3","Tissue RNA - cerebral cortex [nTPM]":"20.0","Tissue RNA - cervix [nTPM]":"6.0","Tissue RNA - choroid plexus [nTPM]":"2.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"5.3","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"2.6","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"3.1","Tissue RNA - lung [nTPM]":"4.8","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"17.4","Tissue RNA - midbrain [nTPM]":"9.1","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"4.7","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"17.7","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"10.4","Tissue RNA - skin 1 [nTPM]":"3.1","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"5.0","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"4.3","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"33.4","Tissue RNA - thalamus [nTPM]":"16.9","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"3.1","Tissue RNA - urinary bladder [nTPM]":"5.3","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"13.8","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"3.8","Cell RNA - AF22 [nTPM]":"8.4","Cell RNA - AN3-CA [nTPM]":"4.2","Cell RNA - ASC diff [nTPM]":"6.5","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"4.6","Cell RNA - BJ hTERT+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.9","Cell RNA - CACO-2 [nTPM]":"4.3","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"3.3","Cell RNA - EFO-21 [nTPM]":"6.1","Cell RNA - fHDF\/TERT166 [nTPM]":"4.7","Cell RNA - GAMG [nTPM]":"9.2","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"6.7","Cell RNA - HBF TERT88 [nTPM]":"6.8","Cell RNA - HDLM-2 [nTPM]":"13.0","Cell RNA - HEK 293 [nTPM]":"3.6","Cell RNA - HEL [nTPM]":"4.8","Cell RNA - HeLa [nTPM]":"6.9","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"5.0","Cell RNA - HL-60 [nTPM]":"6.7","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"6.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.9","Cell RNA - hTERT-HME1 [nTPM]":"21.1","Cell RNA - hTERT-RPE1 [nTPM]":"9.9","Cell RNA - HUVEC TERT2 [nTPM]":"5.2","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"4.9","Cell RNA - LHCN-M2 [nTPM]":"4.5","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"4.1","Cell RNA - NB-4 [nTPM]":"4.3","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"1.7","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"7.2","Cell RNA - RH-30 [nTPM]":"9.1","Cell RNA - RPMI-8226 [nTPM]":"1.7","Cell RNA - RPTEC TERT1 [nTPM]":"5.8","Cell RNA - RT4 [nTPM]":"4.0","Cell RNA - SCLC-21H [nTPM]":"6.6","Cell RNA - SH-SY5Y [nTPM]":"6.5","Cell RNA - SiHa [nTPM]":"12.6","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"2.5","Cell RNA - SuSa [nTPM]":"5.8","Cell RNA - T-47d [nTPM]":"2.6","Cell RNA - THP-1 [nTPM]":"8.7","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"5.1","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"5.7","Cell RNA - U-251 MG [nTPM]":"6.0","Cell RNA - U-266\/70 [nTPM]":"7.1","Cell RNA - U-266\/84 [nTPM]":"11.3","Cell RNA - U-698 [nTPM]":"5.5","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"5.8","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"7.7","Brain RNA - basal ganglia [nTPM]":"9.9","Brain RNA - cerebellum [nTPM]":"11.3","Brain RNA - cerebral cortex [nTPM]":"20.0","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"17.4","Brain RNA - midbrain [nTPM]":"9.1","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"16.9","Brain RNA - white matter [nTPM]":"13.8","Single Cell Type RNA - Adipocytes [nTPM]":"16.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.8","Single Cell Type RNA - Astrocytes [nTPM]":"75.7","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"36.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"80.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.7","Single Cell Type RNA - Endothelial cells [nTPM]":"17.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.3","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"153.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.6","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"16.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"9.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.4","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"185.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.0","Single Cell Type RNA - Langerhans cells [nTPM]":"25.9","Single Cell Type RNA - Late spermatids [nTPM]":"146.2","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"16.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"69.3","Single Cell Type RNA - monocytes [nTPM]":"16.9","Single Cell Type RNA - Muller glia cells [nTPM]":"16.5","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"97.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"125.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"6.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.3","Single Cell Type RNA - Spermatocytes [nTPM]":"34.5","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - T-cells [nTPM]":"13.4","Single Cell Type RNA - Theca cells [nTPM]":"11.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"7.4"},{"Gene":"TTF1","Gene synonym":[],"Ensembl":"ENSG00000125482","Gene description":"Transcription termination factor 1","Uniprot":["Q15361"],"Chromosome":"9","Position":"132375548-132406851","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Transcription termination"],"Molecular function":["DNA replication inhibitor","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054837"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA054837":"AB_2682621"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.40e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.0","Tissue RNA - adrenal gland [nTPM]":"5.0","Tissue RNA - amygdala [nTPM]":"7.0","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"7.7","Tissue RNA - bone marrow [nTPM]":"16.7","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"9.0","Tissue RNA - cerebral cortex [nTPM]":"8.3","Tissue RNA - cervix [nTPM]":"7.4","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"9.0","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"13.3","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"6.6","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"7.0","Tissue RNA - lymph node [nTPM]":"10.5","Tissue RNA - medulla oblongata [nTPM]":"7.0","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"8.6","Tissue RNA - pancreas [nTPM]":"6.6","Tissue RNA - parathyroid gland [nTPM]":"7.0","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"7.1","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"8.6","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"7.4","Tissue RNA - skeletal muscle [nTPM]":"13.6","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"6.5","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"6.8","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"6.5","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"18.9","Tissue RNA - thyroid gland [nTPM]":"10.4","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"10.0","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"12.5","Cell RNA - A549 [nTPM]":"11.5","Cell RNA - AF22 [nTPM]":"16.4","Cell RNA - AN3-CA [nTPM]":"14.8","Cell RNA - ASC diff [nTPM]":"9.0","Cell RNA - ASC TERT1 [nTPM]":"11.5","Cell RNA - BEWO [nTPM]":"14.7","Cell RNA - BJ [nTPM]":"14.1","Cell RNA - BJ hTERT+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.0","Cell RNA - CACO-2 [nTPM]":"11.8","Cell RNA - CAPAN-2 [nTPM]":"13.2","Cell RNA - Daudi [nTPM]":"20.9","Cell RNA - EFO-21 [nTPM]":"11.5","Cell RNA - fHDF\/TERT166 [nTPM]":"10.6","Cell RNA - GAMG [nTPM]":"18.3","Cell RNA - HaCaT [nTPM]":"29.7","Cell RNA - HAP1 [nTPM]":"18.5","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"17.1","Cell RNA - HDLM-2 [nTPM]":"13.9","Cell RNA - HEK 293 [nTPM]":"12.6","Cell RNA - HEL [nTPM]":"9.6","Cell RNA - HeLa [nTPM]":"17.2","Cell RNA - Hep G2 [nTPM]":"9.5","Cell RNA - HHSteC [nTPM]":"9.1","Cell RNA - HL-60 [nTPM]":"25.6","Cell RNA - HMC-1 [nTPM]":"14.9","Cell RNA - HSkMC [nTPM]":"7.1","Cell RNA - hTCEpi [nTPM]":"12.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.8","Cell RNA - hTERT-HME1 [nTPM]":"10.5","Cell RNA - hTERT-RPE1 [nTPM]":"13.1","Cell RNA - HUVEC TERT2 [nTPM]":"14.0","Cell RNA - JURKAT [nTPM]":"34.1","Cell RNA - K-562 [nTPM]":"19.3","Cell RNA - Karpas-707 [nTPM]":"17.5","Cell RNA - LHCN-M2 [nTPM]":"12.7","Cell RNA - MCF7 [nTPM]":"19.0","Cell RNA - MOLT-4 [nTPM]":"59.8","Cell RNA - NB-4 [nTPM]":"15.5","Cell RNA - NTERA-2 [nTPM]":"30.0","Cell RNA - OE19 [nTPM]":"22.3","Cell RNA - PC-3 [nTPM]":"16.8","Cell RNA - REH [nTPM]":"37.1","Cell RNA - RH-30 [nTPM]":"22.8","Cell RNA - RPMI-8226 [nTPM]":"24.9","Cell RNA - RPTEC TERT1 [nTPM]":"13.1","Cell RNA - RT4 [nTPM]":"10.1","Cell RNA - SCLC-21H [nTPM]":"14.4","Cell RNA - SH-SY5Y [nTPM]":"24.8","Cell RNA - SiHa [nTPM]":"19.8","Cell RNA - SK-BR-3 [nTPM]":"14.4","Cell RNA - SK-MEL-30 [nTPM]":"10.7","Cell RNA - SuSa [nTPM]":"15.3","Cell RNA - T-47d [nTPM]":"17.9","Cell RNA - THP-1 [nTPM]":"13.7","Cell RNA - TIME [nTPM]":"13.2","Cell RNA - U-138 MG [nTPM]":"25.0","Cell RNA - U-2 OS [nTPM]":"15.8","Cell RNA - U-2197 [nTPM]":"21.8","Cell RNA - U-251 MG [nTPM]":"16.8","Cell RNA - U-266\/70 [nTPM]":"8.2","Cell RNA - U-266\/84 [nTPM]":"24.8","Cell RNA - U-698 [nTPM]":"25.0","Cell RNA - U-87 MG [nTPM]":"14.7","Cell RNA - U-937 [nTPM]":"20.6","Cell RNA - WM-115 [nTPM]":"25.1","Blood RNA - basophil [nTPM]":"17.0","Blood RNA - classical monocyte [nTPM]":"5.8","Blood RNA - eosinophil [nTPM]":"12.0","Blood RNA - gdT-cell [nTPM]":"6.6","Blood RNA - intermediate monocyte [nTPM]":"6.0","Blood RNA - MAIT T-cell [nTPM]":"8.6","Blood RNA - memory B-cell [nTPM]":"13.6","Blood RNA - memory CD4 T-cell [nTPM]":"8.4","Blood RNA - memory CD8 T-cell [nTPM]":"7.8","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"12.2","Blood RNA - naive CD4 T-cell [nTPM]":"9.3","Blood RNA - naive CD8 T-cell [nTPM]":"7.0","Blood RNA - neutrophil [nTPM]":"20.9","Blood RNA - NK-cell [nTPM]":"8.2","Blood RNA - non-classical monocyte [nTPM]":"7.4","Blood RNA - plasmacytoid DC [nTPM]":"11.2","Blood RNA - T-reg [nTPM]":"9.6","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"7.0","Brain RNA - basal ganglia [nTPM]":"7.7","Brain RNA - cerebellum [nTPM]":"9.0","Brain RNA - cerebral cortex [nTPM]":"8.3","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"7.0","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"7.1","Brain RNA - spinal cord [nTPM]":"6.8","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"26.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.6","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"35.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"27.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"40.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"18.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.8","Single Cell Type RNA - dendritic cells [nTPM]":"33.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"28.5","Single Cell Type RNA - Early spermatids [nTPM]":"22.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.4","Single Cell Type RNA - Endothelial cells [nTPM]":"29.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"68.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.8","Single Cell Type RNA - Fibroblasts [nTPM]":"17.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.8","Single Cell Type RNA - granulocytes [nTPM]":"22.8","Single Cell Type RNA - Granulosa cells [nTPM]":"28.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.5","Single Cell Type RNA - Hepatocytes [nTPM]":"8.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.7","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.4","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"22.0","Single Cell Type RNA - Langerhans cells [nTPM]":"12.1","Single Cell Type RNA - Late spermatids [nTPM]":"6.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.6","Single Cell Type RNA - Macrophages [nTPM]":"17.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"30.1","Single Cell Type RNA - Muller glia cells [nTPM]":"20.3","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.3","Single Cell Type RNA - Paneth cells [nTPM]":"18.6","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"55.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.1","Single Cell Type RNA - Spermatocytes [nTPM]":"47.4","Single Cell Type RNA - Spermatogonia [nTPM]":"61.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - T-cells [nTPM]":"28.2","Single Cell Type RNA - Theca cells [nTPM]":"16.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.7","Single Cell Type RNA - Urothelial cells [nTPM]":"24.5"},{"Gene":"TTLL5","Gene synonym":["KIAA0998"],"Ensembl":"ENSG00000119685","Gene description":"Tubulin tyrosine ligase like 5","Uniprot":["Q6EMB2"],"Chromosome":"14","Position":"75633625-75955079","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription"],"Molecular function":["Ligase"],"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"57.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"127.2","Early spermatids":"111.0","Excitatory neurons":"134.3","Inhibitory neurons":"114.2","Oligodendrocytes":"242.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032128"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA032128":"AB_10600835"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.5","Tissue RNA - adrenal gland [nTPM]":"5.5","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"11.7","Tissue RNA - breast [nTPM]":"7.1","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"7.2","Tissue RNA - cervix [nTPM]":"7.3","Tissue RNA - choroid plexus [nTPM]":"15.0","Tissue RNA - colon [nTPM]":"6.2","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"8.0","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"7.8","Tissue RNA - fallopian tube [nTPM]":"11.6","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"4.1","Tissue RNA - lung [nTPM]":"6.5","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"10.5","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"7.5","Tissue RNA - pons [nTPM]":"10.6","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"7.3","Tissue RNA - retina [nTPM]":"23.9","Tissue RNA - salivary gland [nTPM]":"6.5","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"6.4","Tissue RNA - spleen [nTPM]":"4.1","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"57.4","Tissue RNA - thalamus [nTPM]":"6.4","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"7.8","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"6.1","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"12.0","Cell RNA - A-431 [nTPM]":"22.8","Cell RNA - A549 [nTPM]":"16.2","Cell RNA - AF22 [nTPM]":"13.9","Cell RNA - AN3-CA [nTPM]":"14.5","Cell RNA - ASC diff [nTPM]":"10.9","Cell RNA - ASC TERT1 [nTPM]":"16.8","Cell RNA - BEWO [nTPM]":"12.9","Cell RNA - BJ [nTPM]":"13.1","Cell RNA - BJ hTERT+ [nTPM]":"15.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.9","Cell RNA - CACO-2 [nTPM]":"10.3","Cell RNA - CAPAN-2 [nTPM]":"20.8","Cell RNA - Daudi [nTPM]":"6.4","Cell RNA - EFO-21 [nTPM]":"7.2","Cell RNA - fHDF\/TERT166 [nTPM]":"13.9","Cell RNA - GAMG [nTPM]":"11.3","Cell RNA - HaCaT [nTPM]":"21.3","Cell RNA - HAP1 [nTPM]":"12.3","Cell RNA - HBEC3-KT [nTPM]":"21.7","Cell RNA - HBF TERT88 [nTPM]":"29.3","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"7.3","Cell RNA - HEL [nTPM]":"12.5","Cell RNA - HeLa [nTPM]":"16.8","Cell RNA - Hep G2 [nTPM]":"11.3","Cell RNA - HHSteC [nTPM]":"9.3","Cell RNA - HL-60 [nTPM]":"9.2","Cell RNA - HMC-1 [nTPM]":"11.5","Cell RNA - HSkMC [nTPM]":"13.1","Cell RNA - hTCEpi [nTPM]":"10.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.4","Cell RNA - hTERT-HME1 [nTPM]":"21.5","Cell RNA - hTERT-RPE1 [nTPM]":"16.8","Cell RNA - HUVEC TERT2 [nTPM]":"33.8","Cell RNA - JURKAT [nTPM]":"17.5","Cell RNA - K-562 [nTPM]":"7.2","Cell RNA - Karpas-707 [nTPM]":"10.5","Cell RNA - LHCN-M2 [nTPM]":"15.7","Cell RNA - MCF7 [nTPM]":"32.1","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"12.6","Cell RNA - NTERA-2 [nTPM]":"9.9","Cell RNA - OE19 [nTPM]":"18.0","Cell RNA - PC-3 [nTPM]":"16.6","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"19.6","Cell RNA - RPMI-8226 [nTPM]":"8.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.0","Cell RNA - RT4 [nTPM]":"22.2","Cell RNA - SCLC-21H [nTPM]":"18.4","Cell RNA - SH-SY5Y [nTPM]":"11.6","Cell RNA - SiHa [nTPM]":"27.5","Cell RNA - SK-BR-3 [nTPM]":"20.2","Cell RNA - SK-MEL-30 [nTPM]":"6.8","Cell RNA - SuSa [nTPM]":"11.0","Cell RNA - T-47d [nTPM]":"27.6","Cell RNA - THP-1 [nTPM]":"9.8","Cell RNA - TIME [nTPM]":"38.1","Cell RNA - U-138 MG [nTPM]":"20.5","Cell RNA - U-2 OS [nTPM]":"18.0","Cell RNA - U-2197 [nTPM]":"18.5","Cell RNA - U-251 MG [nTPM]":"12.2","Cell RNA - U-266\/70 [nTPM]":"8.8","Cell RNA - U-266\/84 [nTPM]":"13.5","Cell RNA - U-698 [nTPM]":"14.6","Cell RNA - U-87 MG [nTPM]":"20.7","Cell RNA - U-937 [nTPM]":"10.4","Cell RNA - WM-115 [nTPM]":"13.9","Blood RNA - basophil [nTPM]":"11.6","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"3.2","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"2.3","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"7.2","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"10.5","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"10.6","Brain RNA - spinal cord [nTPM]":"6.4","Brain RNA - thalamus [nTPM]":"6.4","Brain RNA - white matter [nTPM]":"12.0","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.1","Single Cell Type RNA - Astrocytes [nTPM]":"71.8","Single Cell Type RNA - B-cells [nTPM]":"6.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"10.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"127.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.1","Single Cell Type RNA - Early spermatids [nTPM]":"111.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.9","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"134.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.8","Single Cell Type RNA - granulocytes [nTPM]":"12.6","Single Cell Type RNA - Granulosa cells [nTPM]":"11.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"7.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"114.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.5","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"93.1","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"6.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"82.4","Single Cell Type RNA - monocytes [nTPM]":"8.5","Single Cell Type RNA - Muller glia cells [nTPM]":"10.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"242.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.1","Single Cell Type RNA - Paneth cells [nTPM]":"11.9","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"7.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"80.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"37.7","Single Cell Type RNA - Spermatogonia [nTPM]":"16.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - T-cells [nTPM]":"8.3","Single Cell Type RNA - Theca cells [nTPM]":"9.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"TTR","Gene synonym":["CTS","CTS1","HsT2651","PALB"],"Ensembl":"ENSG00000118271","Gene description":"Transthyretin","Uniprot":["P02766"],"Chromosome":"18","Position":"31557009-31598833","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Transport"],"Molecular function":["Hormone","Thyroid hormone"],"Disease involvement":["Amyloidosis","Cancer-related genes","Disease variant","FDA approved drug targets","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"choroid plexus":"142023.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Hepatocytes":"23659.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"28","RNA cancer specific FPKM":{"liver cancer":"928.2","pancreatic cancer":"666.0"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebellum":"621.7","hippocampal formation":"1730.9","thalamus":"688.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"160.1","EFO-21":"39.6","Hep G2":"249.0","U-2 OS":"57.0"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"1538.3","hippocampal formation":"4891.0","pons and medulla":"5758.5","thalamus":"3400.4"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"medulla oblongata":"1381.8"},"Antibody":["CAB002517","HPA002550","CAB062567","CAB073406"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":345000000000,"Blood concentration - Conc. blood MS [pg\/L]":"99000000000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB002517":"AB_563965","CAB062567":"AB_2665620","CAB073406":null,"HPA002550":"AB_1080419"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.2","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"148.5","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"56.7","Tissue RNA - bone marrow [nTPM]":"9.6","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"621.7","Tissue RNA - cerebral cortex [nTPM]":"83.7","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"142023.1","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"14.9","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"51.2","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"1730.9","Tissue RNA - hypothalamus [nTPM]":"37.3","Tissue RNA - kidney [nTPM]":"18.4","Tissue RNA - liver [nTPM]":"21288.1","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"106.5","Tissue RNA - midbrain [nTPM]":"86.0","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"1785.1","Tissue RNA - parathyroid gland [nTPM]":"186.8","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"27.1","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"80.1","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"15.6","Tissue RNA - small intestine [nTPM]":"6.8","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"12.3","Tissue RNA - spleen [nTPM]":"3.8","Tissue RNA - stomach 1 [nTPM]":"49.8","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"688.2","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"133.9","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"160.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"2.9","Cell RNA - EFO-21 [nTPM]":"39.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"5.9","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"5.2","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"249.0","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"11.2","Cell RNA - HMC-1 [nTPM]":"1.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"2.8","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"4.5","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"7.4","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"5.8","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"1.7","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"57.0","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"4.3","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"2.6","Cell RNA - U-698 [nTPM]":"17.6","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"4.3","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"148.5","Brain RNA - basal ganglia [nTPM]":"56.7","Brain RNA - cerebellum [nTPM]":"621.7","Brain RNA - cerebral cortex [nTPM]":"83.7","Brain RNA - hippocampal formation [nTPM]":"1730.9","Brain RNA - hypothalamus [nTPM]":"37.3","Brain RNA - medulla oblongata [nTPM]":"106.5","Brain RNA - midbrain [nTPM]":"86.0","Brain RNA - pons [nTPM]":"27.1","Brain RNA - spinal cord [nTPM]":"12.3","Brain RNA - thalamus [nTPM]":"688.2","Brain RNA - white matter [nTPM]":"133.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"15.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"144.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"779.2","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"162.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"14.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"356.2","Single Cell Type RNA - Erythroid cells [nTPM]":"192.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"192.4","Single Cell Type RNA - Hepatocytes [nTPM]":"23659.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.4","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"313.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"24.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"130.5","Single Cell Type RNA - Paneth cells [nTPM]":"5.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"10.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TUBA3D","Gene synonym":["H2-ALPHA"],"Ensembl":"ENSG00000075886","Gene description":"Tubulin alpha 3d","Uniprot":["P0DPH8"],"Chromosome":"2","Position":"131476119-131482934","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"heart muscle":"86.2","testis":"220.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"358.9","Late spermatids":"119.6","Spermatocytes":"667.9","Spermatogonia":"326.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"7.6"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NB-4":"1.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004972","HPA039247","HPA043684","HPA063394"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB004972":"AB_425727","HPA039247":"AB_2676410","HPA043684":"AB_2678617","HPA063394":"AB_2685003"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.65e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.75e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"86.2","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"10.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"220.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"36.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"358.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"119.6","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"667.9","Single Cell Type RNA - Spermatogonia [nTPM]":"326.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"TUBA4A","Gene synonym":["FLJ30169","H2-ALPHA","TUBA1"],"Ensembl":"ENSG00000127824","Gene description":"Tubulin alpha 4a","Uniprot":["P68366"],"Chromosome":"2","Position":"219249710-219278170","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"360.2","tongue":"210.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"423.0","Late spermatids":"823.0","Pancreatic endocrine cells":"613.5","Smooth muscle cells":"408.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"265.9","HBEC3-KT":"439.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004621","CAB005887","HPA039247","HPA043684","HPA063394"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB004621":"AB_628411","CAB005887":"AB_2288001","HPA039247":"AB_2676410","HPA043684":"AB_2678617","HPA063394":"AB_2685003"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.54e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.3","Tissue RNA - adrenal gland [nTPM]":"41.4","Tissue RNA - amygdala [nTPM]":"33.6","Tissue RNA - appendix [nTPM]":"34.1","Tissue RNA - basal ganglia [nTPM]":"47.5","Tissue RNA - bone marrow [nTPM]":"107.1","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"22.3","Tissue RNA - cerebral cortex [nTPM]":"133.1","Tissue RNA - cervix [nTPM]":"27.7","Tissue RNA - choroid plexus [nTPM]":"8.1","Tissue RNA - colon [nTPM]":"32.9","Tissue RNA - duodenum [nTPM]":"18.6","Tissue RNA - endometrium 1 [nTPM]":"9.8","Tissue RNA - epididymis [nTPM]":"10.1","Tissue RNA - esophagus [nTPM]":"84.8","Tissue RNA - fallopian tube [nTPM]":"12.6","Tissue RNA - gallbladder [nTPM]":"13.5","Tissue RNA - heart muscle [nTPM]":"97.7","Tissue RNA - hippocampal formation [nTPM]":"42.6","Tissue RNA - hypothalamus [nTPM]":"32.3","Tissue RNA - kidney [nTPM]":"31.9","Tissue RNA - liver [nTPM]":"29.5","Tissue RNA - lung [nTPM]":"26.7","Tissue RNA - lymph node [nTPM]":"56.7","Tissue RNA - medulla oblongata [nTPM]":"46.3","Tissue RNA - midbrain [nTPM]":"27.3","Tissue RNA - ovary [nTPM]":"12.9","Tissue RNA - pancreas [nTPM]":"18.2","Tissue RNA - parathyroid gland [nTPM]":"34.6","Tissue RNA - pituitary gland [nTPM]":"23.1","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"31.4","Tissue RNA - prostate [nTPM]":"19.7","Tissue RNA - rectum [nTPM]":"27.8","Tissue RNA - retina [nTPM]":"39.2","Tissue RNA - salivary gland [nTPM]":"46.9","Tissue RNA - seminal vesicle [nTPM]":"22.4","Tissue RNA - skeletal muscle [nTPM]":"360.2","Tissue RNA - skin 1 [nTPM]":"161.4","Tissue RNA - small intestine [nTPM]":"35.5","Tissue RNA - smooth muscle [nTPM]":"12.8","Tissue RNA - spinal cord [nTPM]":"3.9","Tissue RNA - spleen [nTPM]":"56.8","Tissue RNA - stomach 1 [nTPM]":"30.6","Tissue RNA - testis [nTPM]":"32.4","Tissue RNA - thalamus [nTPM]":"14.9","Tissue RNA - thymus [nTPM]":"16.9","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"210.3","Tissue RNA - tonsil [nTPM]":"63.4","Tissue RNA - urinary bladder [nTPM]":"22.6","Tissue RNA - vagina [nTPM]":"57.3","Tissue RNA - white matter [nTPM]":"54.0","Cell RNA - A-431 [nTPM]":"106.0","Cell RNA - A549 [nTPM]":"90.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"9.1","Cell RNA - ASC TERT1 [nTPM]":"6.9","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"16.2","Cell RNA - BJ hTERT+ [nTPM]":"49.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.9","Cell RNA - CACO-2 [nTPM]":"20.4","Cell RNA - CAPAN-2 [nTPM]":"106.7","Cell RNA - Daudi [nTPM]":"144.2","Cell RNA - EFO-21 [nTPM]":"172.2","Cell RNA - fHDF\/TERT166 [nTPM]":"11.7","Cell RNA - GAMG [nTPM]":"172.7","Cell RNA - HaCaT [nTPM]":"265.9","Cell RNA - HAP1 [nTPM]":"49.3","Cell RNA - HBEC3-KT [nTPM]":"439.9","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"81.7","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"184.2","Cell RNA - HeLa [nTPM]":"154.5","Cell RNA - Hep G2 [nTPM]":"15.4","Cell RNA - HHSteC [nTPM]":"7.3","Cell RNA - HL-60 [nTPM]":"60.9","Cell RNA - HMC-1 [nTPM]":"60.8","Cell RNA - HSkMC [nTPM]":"6.7","Cell RNA - hTCEpi [nTPM]":"158.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.7","Cell RNA - hTERT-HME1 [nTPM]":"49.2","Cell RNA - hTERT-RPE1 [nTPM]":"27.4","Cell RNA - HUVEC TERT2 [nTPM]":"17.3","Cell RNA - JURKAT [nTPM]":"2.4","Cell RNA - K-562 [nTPM]":"20.5","Cell RNA - Karpas-707 [nTPM]":"91.3","Cell RNA - LHCN-M2 [nTPM]":"100.6","Cell RNA - MCF7 [nTPM]":"4.3","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"107.9","Cell RNA - NTERA-2 [nTPM]":"32.3","Cell RNA - OE19 [nTPM]":"83.2","Cell RNA - PC-3 [nTPM]":"107.4","Cell RNA - REH [nTPM]":"6.5","Cell RNA - RH-30 [nTPM]":"139.0","Cell RNA - RPMI-8226 [nTPM]":"84.5","Cell RNA - RPTEC TERT1 [nTPM]":"129.7","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"85.8","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"213.2","Cell RNA - SK-BR-3 [nTPM]":"18.7","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"1.8","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"50.9","Cell RNA - TIME [nTPM]":"12.3","Cell RNA - U-138 MG [nTPM]":"49.8","Cell RNA - U-2 OS [nTPM]":"27.4","Cell RNA - U-2197 [nTPM]":"58.4","Cell RNA - U-251 MG [nTPM]":"56.7","Cell RNA - U-266\/70 [nTPM]":"38.0","Cell RNA - U-266\/84 [nTPM]":"48.8","Cell RNA - U-698 [nTPM]":"171.4","Cell RNA - U-87 MG [nTPM]":"183.3","Cell RNA - U-937 [nTPM]":"116.4","Cell RNA - WM-115 [nTPM]":"2.5","Blood RNA - basophil [nTPM]":"141.7","Blood RNA - classical monocyte [nTPM]":"63.3","Blood RNA - eosinophil [nTPM]":"170.2","Blood RNA - gdT-cell [nTPM]":"107.1","Blood RNA - intermediate monocyte [nTPM]":"45.7","Blood RNA - MAIT T-cell [nTPM]":"110.1","Blood RNA - memory B-cell [nTPM]":"124.9","Blood RNA - memory CD4 T-cell [nTPM]":"150.3","Blood RNA - memory CD8 T-cell [nTPM]":"142.8","Blood RNA - myeloid DC [nTPM]":"20.9","Blood RNA - naive B-cell [nTPM]":"95.5","Blood RNA - naive CD4 T-cell [nTPM]":"140.2","Blood RNA - naive CD8 T-cell [nTPM]":"138.4","Blood RNA - neutrophil [nTPM]":"331.2","Blood RNA - NK-cell [nTPM]":"82.0","Blood RNA - non-classical monocyte [nTPM]":"71.9","Blood RNA - plasmacytoid DC [nTPM]":"3.8","Blood RNA - T-reg [nTPM]":"143.8","Blood RNA - total PBMC [nTPM]":"270.9","Brain RNA - amygdala [nTPM]":"33.6","Brain RNA - basal ganglia [nTPM]":"47.5","Brain RNA - cerebellum [nTPM]":"22.3","Brain RNA - cerebral cortex [nTPM]":"133.1","Brain RNA - hippocampal formation [nTPM]":"42.6","Brain RNA - hypothalamus [nTPM]":"32.3","Brain RNA - medulla oblongata [nTPM]":"46.3","Brain RNA - midbrain [nTPM]":"27.3","Brain RNA - pons [nTPM]":"31.4","Brain RNA - spinal cord [nTPM]":"3.9","Brain RNA - thalamus [nTPM]":"14.9","Brain RNA - white matter [nTPM]":"54.0","Single Cell Type RNA - Adipocytes [nTPM]":"55.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"160.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"181.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"201.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"235.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"68.9","Single Cell Type RNA - Bipolar cells [nTPM]":"123.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"51.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"60.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"62.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"77.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"311.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"87.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"140.8","Single Cell Type RNA - Ductal cells [nTPM]":"199.3","Single Cell Type RNA - Early spermatids [nTPM]":"423.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.3","Single Cell Type RNA - Endothelial cells [nTPM]":"36.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"107.9","Single Cell Type RNA - Erythroid cells [nTPM]":"56.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"205.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.1","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.0","Single Cell Type RNA - Hepatocytes [nTPM]":"33.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.0","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"141.9","Single Cell Type RNA - Ionocytes [nTPM]":"48.8","Single Cell Type RNA - Kupffer cells [nTPM]":"15.3","Single Cell Type RNA - Langerhans cells [nTPM]":"54.9","Single Cell Type RNA - Late spermatids [nTPM]":"823.0","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"159.5","Single Cell Type RNA - Melanocytes [nTPM]":"78.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"27.8","Single Cell Type RNA - Muller glia cells [nTPM]":"38.6","Single Cell Type RNA - NK-cells [nTPM]":"50.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"613.5","Single Cell Type RNA - Paneth cells [nTPM]":"51.2","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"202.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"87.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"137.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"72.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"408.5","Single Cell Type RNA - Spermatocytes [nTPM]":"5.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"130.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"244.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"290.1","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"58.9","Single Cell Type RNA - Urothelial cells [nTPM]":"113.0"},{"Gene":"TUBB3","Gene synonym":["beta-4","CFEOM3","CFEOM3A","FEOM3"],"Ensembl":"ENSG00000258947","Gene description":"Tubulin beta 3 class III","Uniprot":["Q13509"],"Chromosome":"16","Position":"89921392-89938761","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"313.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"20.2","Ductal cells":"28.7","Excitatory neurons":"37.9","Exocrine glandular cells":"21.4","Gastric mucus-secreting cells":"27.0","Inhibitory neurons":"45.1","Pancreatic endocrine cells":"49.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"naive B-cell":"2.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"2.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"421.3","SCLC-21H":"424.9","SH-SY5Y":"433.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043640","HPA046280"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytokinetic bridge","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"89000000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Microtubules"],"Subcellular additional location":["Cytokinetic bridge","Mitotic spindle"],"Antibody RRID":{"HPA043640":"AB_2678594","HPA046280":"AB_2679612"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.7","Tissue RNA - adrenal gland [nTPM]":"24.8","Tissue RNA - amygdala [nTPM]":"99.4","Tissue RNA - appendix [nTPM]":"12.1","Tissue RNA - basal ganglia [nTPM]":"93.3","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"100.5","Tissue RNA - cerebral cortex [nTPM]":"127.6","Tissue RNA - cervix [nTPM]":"3.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"18.4","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"3.6","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"5.5","Tissue RNA - hippocampal formation [nTPM]":"88.6","Tissue RNA - hypothalamus [nTPM]":"313.3","Tissue RNA - kidney [nTPM]":"13.3","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"7.1","Tissue RNA - medulla oblongata [nTPM]":"208.8","Tissue RNA - midbrain [nTPM]":"132.7","Tissue RNA - ovary [nTPM]":"3.9","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"55.1","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"266.2","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"24.8","Tissue RNA - salivary gland [nTPM]":"10.6","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"8.0","Tissue RNA - smooth muscle [nTPM]":"12.7","Tissue RNA - spinal cord [nTPM]":"74.2","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"7.2","Tissue RNA - testis [nTPM]":"38.0","Tissue RNA - thalamus [nTPM]":"183.4","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"82.5","Cell RNA - A-431 [nTPM]":"30.1","Cell RNA - A549 [nTPM]":"421.3","Cell RNA - AF22 [nTPM]":"152.6","Cell RNA - AN3-CA [nTPM]":"173.9","Cell RNA - ASC diff [nTPM]":"17.9","Cell RNA - ASC TERT1 [nTPM]":"170.8","Cell RNA - BEWO [nTPM]":"6.8","Cell RNA - BJ [nTPM]":"181.0","Cell RNA - BJ hTERT+ [nTPM]":"31.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"105.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.2","Cell RNA - CACO-2 [nTPM]":"57.2","Cell RNA - CAPAN-2 [nTPM]":"53.5","Cell RNA - Daudi [nTPM]":"89.6","Cell RNA - EFO-21 [nTPM]":"93.6","Cell RNA - fHDF\/TERT166 [nTPM]":"136.8","Cell RNA - GAMG [nTPM]":"74.3","Cell RNA - HaCaT [nTPM]":"112.1","Cell RNA - HAP1 [nTPM]":"148.9","Cell RNA - HBEC3-KT [nTPM]":"26.7","Cell RNA - HBF TERT88 [nTPM]":"26.3","Cell RNA - HDLM-2 [nTPM]":"22.7","Cell RNA - HEK 293 [nTPM]":"15.5","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"32.5","Cell RNA - Hep G2 [nTPM]":"383.7","Cell RNA - HHSteC [nTPM]":"6.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"67.6","Cell RNA - HSkMC [nTPM]":"98.4","Cell RNA - hTCEpi [nTPM]":"7.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"161.9","Cell RNA - hTERT-HME1 [nTPM]":"14.0","Cell RNA - hTERT-RPE1 [nTPM]":"136.8","Cell RNA - HUVEC TERT2 [nTPM]":"88.4","Cell RNA - JURKAT [nTPM]":"5.9","Cell RNA - K-562 [nTPM]":"9.2","Cell RNA - Karpas-707 [nTPM]":"2.5","Cell RNA - LHCN-M2 [nTPM]":"122.3","Cell RNA - MCF7 [nTPM]":"288.6","Cell RNA - MOLT-4 [nTPM]":"1.2","Cell RNA - NB-4 [nTPM]":"31.5","Cell RNA - NTERA-2 [nTPM]":"274.3","Cell RNA - OE19 [nTPM]":"11.2","Cell RNA - PC-3 [nTPM]":"237.3","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"54.1","Cell RNA - RPMI-8226 [nTPM]":"9.5","Cell RNA - RPTEC TERT1 [nTPM]":"131.8","Cell RNA - RT4 [nTPM]":"8.1","Cell RNA - SCLC-21H [nTPM]":"424.9","Cell RNA - SH-SY5Y [nTPM]":"433.8","Cell RNA - SiHa [nTPM]":"251.2","Cell RNA - SK-BR-3 [nTPM]":"4.4","Cell RNA - SK-MEL-30 [nTPM]":"137.1","Cell RNA - SuSa [nTPM]":"27.5","Cell RNA - T-47d [nTPM]":"15.0","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"110.9","Cell RNA - U-138 MG [nTPM]":"142.8","Cell RNA - U-2 OS [nTPM]":"156.9","Cell RNA - U-2197 [nTPM]":"197.3","Cell RNA - U-251 MG [nTPM]":"185.3","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"19.6","Cell RNA - U-698 [nTPM]":"35.2","Cell RNA - U-87 MG [nTPM]":"150.2","Cell RNA - U-937 [nTPM]":"11.5","Cell RNA - WM-115 [nTPM]":"260.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"99.4","Brain RNA - basal ganglia [nTPM]":"93.3","Brain RNA - cerebellum [nTPM]":"100.5","Brain RNA - cerebral cortex [nTPM]":"127.6","Brain RNA - hippocampal formation [nTPM]":"88.6","Brain RNA - hypothalamus [nTPM]":"313.3","Brain RNA - medulla oblongata [nTPM]":"208.8","Brain RNA - midbrain [nTPM]":"132.7","Brain RNA - pons [nTPM]":"266.2","Brain RNA - spinal cord [nTPM]":"74.2","Brain RNA - thalamus [nTPM]":"183.4","Brain RNA - white matter [nTPM]":"82.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"20.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"28.7","Single Cell Type RNA - Early spermatids [nTPM]":"8.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"16.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TUBB4B","Gene synonym":["Beta2","TUBB2C"],"Ensembl":"ENSG00000188229","Gene description":"Tubulin beta 4B class IVb","Uniprot":["P68371"],"Chromosome":"9","Position":"137241287-137243707","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","FDA approved drug targets","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"2190.0","Late spermatids":"2907.1","Spermatocytes":"1717.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010880","HPA043640","HPA046280"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules","Cytokinetic bridge","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Microtubules"],"Subcellular additional location":["Cytokinetic bridge","Mitotic spindle"],"Antibody RRID":{"CAB010880":"AB_609915","HPA043640":"AB_2678594","HPA046280":"AB_2679612"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.91e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.98e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.36e-6"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Tissue RNA - adipose tissue [nTPM]":"134.5","Tissue RNA - adrenal gland [nTPM]":"112.6","Tissue RNA - amygdala [nTPM]":"162.0","Tissue RNA - appendix [nTPM]":"97.2","Tissue RNA - basal ganglia [nTPM]":"163.4","Tissue RNA - bone marrow [nTPM]":"423.9","Tissue RNA - breast [nTPM]":"94.4","Tissue RNA - cerebellum [nTPM]":"149.4","Tissue RNA - cerebral cortex [nTPM]":"182.7","Tissue RNA - cervix [nTPM]":"88.1","Tissue RNA - choroid plexus [nTPM]":"482.7","Tissue RNA - colon [nTPM]":"198.3","Tissue RNA - duodenum [nTPM]":"142.0","Tissue RNA - endometrium 1 [nTPM]":"107.7","Tissue RNA - epididymis [nTPM]":"209.1","Tissue RNA - esophagus [nTPM]":"343.3","Tissue RNA - fallopian tube [nTPM]":"507.2","Tissue RNA - gallbladder [nTPM]":"106.0","Tissue RNA - heart muscle [nTPM]":"435.8","Tissue RNA - hippocampal formation [nTPM]":"174.0","Tissue RNA - hypothalamus [nTPM]":"185.2","Tissue RNA - kidney [nTPM]":"122.5","Tissue RNA - liver [nTPM]":"140.1","Tissue RNA - lung [nTPM]":"130.5","Tissue RNA - lymph node [nTPM]":"95.5","Tissue RNA - medulla oblongata [nTPM]":"184.1","Tissue RNA - midbrain [nTPM]":"233.6","Tissue RNA - ovary [nTPM]":"72.9","Tissue RNA - pancreas [nTPM]":"123.8","Tissue RNA - parathyroid gland [nTPM]":"87.8","Tissue RNA - pituitary gland [nTPM]":"118.0","Tissue RNA - placenta [nTPM]":"86.3","Tissue RNA - pons [nTPM]":"213.9","Tissue RNA - prostate [nTPM]":"120.2","Tissue RNA - rectum [nTPM]":"111.9","Tissue RNA - retina [nTPM]":"261.8","Tissue RNA - salivary gland [nTPM]":"177.9","Tissue RNA - seminal vesicle [nTPM]":"121.5","Tissue RNA - skeletal muscle [nTPM]":"202.5","Tissue RNA - skin 1 [nTPM]":"240.0","Tissue RNA - small intestine [nTPM]":"166.4","Tissue RNA - smooth muscle [nTPM]":"119.8","Tissue RNA - spinal cord [nTPM]":"162.9","Tissue RNA - spleen [nTPM]":"85.6","Tissue RNA - stomach 1 [nTPM]":"161.4","Tissue RNA - testis [nTPM]":"765.7","Tissue RNA - thalamus [nTPM]":"192.6","Tissue RNA - thymus [nTPM]":"162.9","Tissue RNA - thyroid gland [nTPM]":"115.7","Tissue RNA - tongue [nTPM]":"96.6","Tissue RNA - tonsil [nTPM]":"119.7","Tissue RNA - urinary bladder [nTPM]":"188.3","Tissue RNA - vagina [nTPM]":"139.4","Tissue RNA - white matter [nTPM]":"133.9","Cell RNA - A-431 [nTPM]":"706.2","Cell RNA - A549 [nTPM]":"1032.5","Cell RNA - AF22 [nTPM]":"431.7","Cell RNA - AN3-CA [nTPM]":"314.2","Cell RNA - ASC diff [nTPM]":"213.2","Cell RNA - ASC TERT1 [nTPM]":"223.6","Cell RNA - BEWO [nTPM]":"600.5","Cell RNA - BJ [nTPM]":"643.7","Cell RNA - BJ hTERT+ [nTPM]":"536.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"872.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"598.6","Cell RNA - CACO-2 [nTPM]":"1101.0","Cell RNA - CAPAN-2 [nTPM]":"840.2","Cell RNA - Daudi [nTPM]":"429.0","Cell RNA - EFO-21 [nTPM]":"480.2","Cell RNA - fHDF\/TERT166 [nTPM]":"631.2","Cell RNA - GAMG [nTPM]":"848.2","Cell RNA - HaCaT [nTPM]":"1305.1","Cell RNA - HAP1 [nTPM]":"539.5","Cell RNA - HBEC3-KT [nTPM]":"1039.2","Cell RNA - HBF TERT88 [nTPM]":"330.2","Cell RNA - HDLM-2 [nTPM]":"307.9","Cell RNA - HEK 293 [nTPM]":"458.5","Cell RNA - HEL [nTPM]":"311.2","Cell RNA - HeLa [nTPM]":"789.6","Cell RNA - Hep G2 [nTPM]":"877.8","Cell RNA - HHSteC [nTPM]":"134.5","Cell RNA - HL-60 [nTPM]":"370.0","Cell RNA - HMC-1 [nTPM]":"331.5","Cell RNA - HSkMC [nTPM]":"145.0","Cell RNA - hTCEpi [nTPM]":"291.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"667.5","Cell RNA - hTERT-HME1 [nTPM]":"183.1","Cell RNA - hTERT-RPE1 [nTPM]":"215.7","Cell RNA - HUVEC TERT2 [nTPM]":"631.7","Cell RNA - JURKAT [nTPM]":"300.6","Cell RNA - K-562 [nTPM]":"443.0","Cell RNA - Karpas-707 [nTPM]":"239.7","Cell RNA - LHCN-M2 [nTPM]":"731.2","Cell RNA - MCF7 [nTPM]":"1936.4","Cell RNA - MOLT-4 [nTPM]":"337.4","Cell RNA - NB-4 [nTPM]":"504.2","Cell RNA - NTERA-2 [nTPM]":"457.8","Cell RNA - OE19 [nTPM]":"1234.8","Cell RNA - PC-3 [nTPM]":"1778.1","Cell RNA - REH [nTPM]":"423.5","Cell RNA - RH-30 [nTPM]":"822.2","Cell RNA - RPMI-8226 [nTPM]":"394.2","Cell RNA - RPTEC TERT1 [nTPM]":"666.8","Cell RNA - RT4 [nTPM]":"647.8","Cell RNA - SCLC-21H [nTPM]":"301.5","Cell RNA - SH-SY5Y [nTPM]":"323.6","Cell RNA - SiHa [nTPM]":"853.9","Cell RNA - SK-BR-3 [nTPM]":"485.8","Cell RNA - SK-MEL-30 [nTPM]":"173.2","Cell RNA - SuSa [nTPM]":"244.2","Cell RNA - T-47d [nTPM]":"699.0","Cell RNA - THP-1 [nTPM]":"397.6","Cell RNA - TIME [nTPM]":"495.6","Cell RNA - U-138 MG [nTPM]":"618.1","Cell RNA - U-2 OS [nTPM]":"685.0","Cell RNA - U-2197 [nTPM]":"710.0","Cell RNA - U-251 MG [nTPM]":"863.6","Cell RNA - U-266\/70 [nTPM]":"92.4","Cell RNA - U-266\/84 [nTPM]":"274.9","Cell RNA - U-698 [nTPM]":"475.1","Cell RNA - U-87 MG [nTPM]":"503.6","Cell RNA - U-937 [nTPM]":"286.9","Cell RNA - WM-115 [nTPM]":"549.8","Blood RNA - basophil [nTPM]":"95.7","Blood RNA - classical monocyte [nTPM]":"30.0","Blood RNA - eosinophil [nTPM]":"43.2","Blood RNA - gdT-cell [nTPM]":"40.5","Blood RNA - intermediate monocyte [nTPM]":"30.1","Blood RNA - MAIT T-cell [nTPM]":"38.2","Blood RNA - memory B-cell [nTPM]":"32.6","Blood RNA - memory CD4 T-cell [nTPM]":"31.3","Blood RNA - memory CD8 T-cell [nTPM]":"34.4","Blood RNA - myeloid DC [nTPM]":"34.9","Blood RNA - naive B-cell [nTPM]":"30.8","Blood RNA - naive CD4 T-cell [nTPM]":"19.7","Blood RNA - naive CD8 T-cell [nTPM]":"26.7","Blood RNA - neutrophil [nTPM]":"56.4","Blood RNA - NK-cell [nTPM]":"24.4","Blood RNA - non-classical monocyte [nTPM]":"30.5","Blood RNA - plasmacytoid DC [nTPM]":"36.3","Blood RNA - T-reg [nTPM]":"44.7","Blood RNA - total PBMC [nTPM]":"32.6","Brain RNA - amygdala [nTPM]":"162.0","Brain RNA - basal ganglia [nTPM]":"163.4","Brain RNA - cerebellum [nTPM]":"149.4","Brain RNA - cerebral cortex [nTPM]":"182.7","Brain RNA - hippocampal formation [nTPM]":"174.0","Brain RNA - hypothalamus [nTPM]":"185.2","Brain RNA - medulla oblongata [nTPM]":"184.1","Brain RNA - midbrain [nTPM]":"233.6","Brain RNA - pons [nTPM]":"213.9","Brain RNA - spinal cord [nTPM]":"162.9","Brain RNA - thalamus [nTPM]":"192.6","Brain RNA - white matter [nTPM]":"133.9","Single Cell Type RNA - Adipocytes [nTPM]":"478.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"221.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"146.3","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"315.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"326.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"945.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"458.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"327.2","Single Cell Type RNA - Bipolar cells [nTPM]":"508.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"286.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"389.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"91.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"143.0","Single Cell Type RNA - Club cells [nTPM]":"284.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"143.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"300.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"346.6","Single Cell Type RNA - dendritic cells [nTPM]":"640.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"744.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"221.1","Single Cell Type RNA - Ductal cells [nTPM]":"348.6","Single Cell Type RNA - Early spermatids [nTPM]":"2190.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1191.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"224.8","Single Cell Type RNA - Endothelial cells [nTPM]":"203.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"391.5","Single Cell Type RNA - Erythroid cells [nTPM]":"419.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"446.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"545.5","Single Cell Type RNA - Fibroblasts [nTPM]":"247.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"274.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"415.0","Single Cell Type RNA - granulocytes [nTPM]":"189.2","Single Cell Type RNA - Granulosa cells [nTPM]":"200.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"142.5","Single Cell Type RNA - Hepatocytes [nTPM]":"139.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"265.9","Single Cell Type RNA - Horizontal cells [nTPM]":"244.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"503.6","Single Cell Type RNA - Ionocytes [nTPM]":"323.5","Single Cell Type RNA - Kupffer cells [nTPM]":"59.9","Single Cell Type RNA - Langerhans cells [nTPM]":"214.9","Single Cell Type RNA - Late spermatids [nTPM]":"2907.1","Single Cell Type RNA - Leydig cells [nTPM]":"254.2","Single Cell Type RNA - Macrophages [nTPM]":"299.3","Single Cell Type RNA - Melanocytes [nTPM]":"138.7","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"224.0","Single Cell Type RNA - Muller glia cells [nTPM]":"299.3","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"477.4","Single Cell Type RNA - Paneth cells [nTPM]":"697.2","Single Cell Type RNA - Peritubular cells [nTPM]":"153.1","Single Cell Type RNA - Plasma cells [nTPM]":"264.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"475.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"540.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"345.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1558.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"763.3","Single Cell Type RNA - Sertoli cells [nTPM]":"111.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"261.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"416.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1717.5","Single Cell Type RNA - Spermatogonia [nTPM]":"740.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"419.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"297.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"321.1","Single Cell Type RNA - T-cells [nTPM]":"362.9","Single Cell Type RNA - Theca cells [nTPM]":"89.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"487.3","Single Cell Type RNA - Urothelial cells [nTPM]":"592.7"},{"Gene":"TULP1","Gene synonym":["LCA15","RP14","TUBL1"],"Ensembl":"ENSG00000112041","Gene description":"TUB like protein 1","Uniprot":["O00294"],"Chromosome":"6","Position":"35497874-35512896","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Phagocytosis","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Leber congenital amaurosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"286","RNA tissue specific nTPM":{"retina":"209.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"266.9","Rod photoreceptor cells":"393.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"2.7","MCF7":"1.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"209.1","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"64.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"266.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"55.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"393.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"TWNK","Gene synonym":["C10orf2","FLJ21832","IOSCA","PEO","PEO1","TWINKLE","TWINL"],"Ensembl":"ENSG00000107815","Gene description":"Twinkle mtDNA helicase","Uniprot":["Q96RR1"],"Chromosome":"10","Position":"100987367-100994403","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA replication"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Deafness","Disease variant","Neurodegeneration","Neuropathy","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"6.8","Breast myoepithelial cells":"6.6","Ductal cells":"5.4","Endometrial stromal cells":"7.2","Granulosa cells":"7.1","Theca cells":"9.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002532"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002532":"AB_1078311"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"7.5","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"3.5","Tissue RNA - cervix [nTPM]":"3.8","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"4.4","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"4.6","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"6.6","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"5.0","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"5.9","Tissue RNA - liver [nTPM]":"6.0","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"4.0","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"11.6","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"12.6","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"6.6","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"15.5","Cell RNA - A549 [nTPM]":"32.0","Cell RNA - AF22 [nTPM]":"12.5","Cell RNA - AN3-CA [nTPM]":"39.7","Cell RNA - ASC diff [nTPM]":"11.1","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"14.7","Cell RNA - BJ [nTPM]":"11.4","Cell RNA - BJ hTERT+ [nTPM]":"14.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.6","Cell RNA - CACO-2 [nTPM]":"52.6","Cell RNA - CAPAN-2 [nTPM]":"13.1","Cell RNA - Daudi [nTPM]":"55.4","Cell RNA - EFO-21 [nTPM]":"21.1","Cell RNA - fHDF\/TERT166 [nTPM]":"7.0","Cell RNA - GAMG [nTPM]":"10.4","Cell RNA - HaCaT [nTPM]":"25.0","Cell RNA - HAP1 [nTPM]":"52.2","Cell RNA - HBEC3-KT [nTPM]":"27.7","Cell RNA - HBF TERT88 [nTPM]":"21.1","Cell RNA - HDLM-2 [nTPM]":"25.5","Cell RNA - HEK 293 [nTPM]":"31.0","Cell RNA - HEL [nTPM]":"42.1","Cell RNA - HeLa [nTPM]":"17.4","Cell RNA - Hep G2 [nTPM]":"40.2","Cell RNA - HHSteC [nTPM]":"19.1","Cell RNA - HL-60 [nTPM]":"54.8","Cell RNA - HMC-1 [nTPM]":"16.7","Cell RNA - HSkMC [nTPM]":"14.9","Cell RNA - hTCEpi [nTPM]":"30.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.5","Cell RNA - hTERT-HME1 [nTPM]":"77.6","Cell RNA - hTERT-RPE1 [nTPM]":"15.8","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"26.3","Cell RNA - K-562 [nTPM]":"45.9","Cell RNA - Karpas-707 [nTPM]":"15.0","Cell RNA - LHCN-M2 [nTPM]":"12.3","Cell RNA - MCF7 [nTPM]":"21.2","Cell RNA - MOLT-4 [nTPM]":"37.0","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"35.8","Cell RNA - OE19 [nTPM]":"28.2","Cell RNA - PC-3 [nTPM]":"25.9","Cell RNA - REH [nTPM]":"35.5","Cell RNA - RH-30 [nTPM]":"27.5","Cell RNA - RPMI-8226 [nTPM]":"33.2","Cell RNA - RPTEC TERT1 [nTPM]":"10.7","Cell RNA - RT4 [nTPM]":"15.4","Cell RNA - SCLC-21H [nTPM]":"20.1","Cell RNA - SH-SY5Y [nTPM]":"38.5","Cell RNA - SiHa [nTPM]":"12.0","Cell RNA - SK-BR-3 [nTPM]":"16.0","Cell RNA - SK-MEL-30 [nTPM]":"37.8","Cell RNA - SuSa [nTPM]":"13.8","Cell RNA - T-47d [nTPM]":"20.9","Cell RNA - THP-1 [nTPM]":"16.0","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"8.6","Cell RNA - U-2 OS [nTPM]":"17.4","Cell RNA - U-2197 [nTPM]":"10.6","Cell RNA - U-251 MG [nTPM]":"32.5","Cell RNA - U-266\/70 [nTPM]":"28.0","Cell RNA - U-266\/84 [nTPM]":"31.3","Cell RNA - U-698 [nTPM]":"46.0","Cell RNA - U-87 MG [nTPM]":"10.6","Cell RNA - U-937 [nTPM]":"47.8","Cell RNA - WM-115 [nTPM]":"9.8","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"2.5","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"3.5","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"4.0","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.7","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"9.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"UBA1","Gene synonym":["A1S9T","CFAP124","GXP1","POC20","UBE1","UBE1X"],"Ensembl":"ENSG00000130985","Gene description":"Ubiquitin like modifier activating enzyme 1","Uniprot":["P22314"],"Chromosome":"X","Position":"47190861-47215128","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Ligase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000289","HPA001506","CAB019435","CAB073410"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB019435":"AB_2211440","CAB073410":null,"HPA000289":"AB_1080443","HPA001506":"AB_2756305"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.10e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.78e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"98.4","Tissue RNA - adrenal gland [nTPM]":"157.9","Tissue RNA - amygdala [nTPM]":"102.9","Tissue RNA - appendix [nTPM]":"98.3","Tissue RNA - basal ganglia [nTPM]":"113.2","Tissue RNA - bone marrow [nTPM]":"94.3","Tissue RNA - breast [nTPM]":"98.6","Tissue RNA - cerebellum [nTPM]":"103.4","Tissue RNA - cerebral cortex [nTPM]":"115.5","Tissue RNA - cervix [nTPM]":"127.9","Tissue RNA - choroid plexus [nTPM]":"133.9","Tissue RNA - colon [nTPM]":"101.1","Tissue RNA - duodenum [nTPM]":"71.3","Tissue RNA - endometrium 1 [nTPM]":"127.1","Tissue RNA - epididymis [nTPM]":"64.3","Tissue RNA - esophagus [nTPM]":"155.3","Tissue RNA - fallopian tube [nTPM]":"119.3","Tissue RNA - gallbladder [nTPM]":"64.9","Tissue RNA - heart muscle [nTPM]":"117.4","Tissue RNA - hippocampal formation [nTPM]":"106.2","Tissue RNA - hypothalamus [nTPM]":"102.0","Tissue RNA - kidney [nTPM]":"131.2","Tissue RNA - liver [nTPM]":"114.7","Tissue RNA - lung [nTPM]":"109.5","Tissue RNA - lymph node [nTPM]":"105.0","Tissue RNA - medulla oblongata [nTPM]":"106.9","Tissue RNA - midbrain [nTPM]":"104.2","Tissue RNA - ovary [nTPM]":"136.5","Tissue RNA - pancreas [nTPM]":"89.0","Tissue RNA - parathyroid gland [nTPM]":"107.5","Tissue RNA - pituitary gland [nTPM]":"135.2","Tissue RNA - placenta [nTPM]":"67.4","Tissue RNA - pons [nTPM]":"109.3","Tissue RNA - prostate [nTPM]":"103.2","Tissue RNA - rectum [nTPM]":"68.5","Tissue RNA - retina [nTPM]":"95.6","Tissue RNA - salivary gland [nTPM]":"119.5","Tissue RNA - seminal vesicle [nTPM]":"78.9","Tissue RNA - skeletal muscle [nTPM]":"201.1","Tissue RNA - skin 1 [nTPM]":"119.5","Tissue RNA - small intestine [nTPM]":"100.4","Tissue RNA - smooth muscle [nTPM]":"117.4","Tissue RNA - spinal cord [nTPM]":"94.4","Tissue RNA - spleen [nTPM]":"131.9","Tissue RNA - stomach 1 [nTPM]":"98.6","Tissue RNA - testis [nTPM]":"98.7","Tissue RNA - thalamus [nTPM]":"110.0","Tissue RNA - thymus [nTPM]":"119.7","Tissue RNA - thyroid gland [nTPM]":"160.1","Tissue RNA - tongue [nTPM]":"114.1","Tissue RNA - tonsil [nTPM]":"110.8","Tissue RNA - urinary bladder [nTPM]":"101.1","Tissue RNA - vagina [nTPM]":"124.8","Tissue RNA - white matter [nTPM]":"121.3","Cell RNA - A-431 [nTPM]":"269.1","Cell RNA - A549 [nTPM]":"273.2","Cell RNA - AF22 [nTPM]":"307.7","Cell RNA - AN3-CA [nTPM]":"471.9","Cell RNA - ASC diff [nTPM]":"207.4","Cell RNA - ASC TERT1 [nTPM]":"186.8","Cell RNA - BEWO [nTPM]":"135.0","Cell RNA - BJ [nTPM]":"175.1","Cell RNA - BJ hTERT+ [nTPM]":"187.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"248.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"200.5","Cell RNA - CACO-2 [nTPM]":"219.3","Cell RNA - CAPAN-2 [nTPM]":"201.3","Cell RNA - Daudi [nTPM]":"201.6","Cell RNA - EFO-21 [nTPM]":"111.8","Cell RNA - fHDF\/TERT166 [nTPM]":"357.0","Cell RNA - GAMG [nTPM]":"361.5","Cell RNA - HaCaT [nTPM]":"254.9","Cell RNA - HAP1 [nTPM]":"392.9","Cell RNA - HBEC3-KT [nTPM]":"375.7","Cell RNA - HBF TERT88 [nTPM]":"180.9","Cell RNA - HDLM-2 [nTPM]":"163.4","Cell RNA - HEK 293 [nTPM]":"391.7","Cell RNA - HEL [nTPM]":"126.1","Cell RNA - HeLa [nTPM]":"295.2","Cell RNA - Hep G2 [nTPM]":"180.0","Cell RNA - HHSteC [nTPM]":"145.1","Cell RNA - HL-60 [nTPM]":"215.2","Cell RNA - HMC-1 [nTPM]":"258.8","Cell RNA - HSkMC [nTPM]":"177.4","Cell RNA - hTCEpi [nTPM]":"193.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"362.7","Cell RNA - hTERT-HME1 [nTPM]":"279.4","Cell RNA - hTERT-RPE1 [nTPM]":"176.7","Cell RNA - HUVEC TERT2 [nTPM]":"330.2","Cell RNA - JURKAT [nTPM]":"236.1","Cell RNA - K-562 [nTPM]":"138.9","Cell RNA - Karpas-707 [nTPM]":"173.7","Cell RNA - LHCN-M2 [nTPM]":"250.4","Cell RNA - MCF7 [nTPM]":"343.4","Cell RNA - MOLT-4 [nTPM]":"203.3","Cell RNA - NB-4 [nTPM]":"188.5","Cell RNA - NTERA-2 [nTPM]":"329.6","Cell RNA - OE19 [nTPM]":"163.2","Cell RNA - PC-3 [nTPM]":"417.1","Cell RNA - REH [nTPM]":"233.1","Cell RNA - RH-30 [nTPM]":"215.3","Cell RNA - RPMI-8226 [nTPM]":"343.7","Cell RNA - RPTEC TERT1 [nTPM]":"198.7","Cell RNA - RT4 [nTPM]":"287.0","Cell RNA - SCLC-21H [nTPM]":"197.4","Cell RNA - SH-SY5Y [nTPM]":"148.1","Cell RNA - SiHa [nTPM]":"520.8","Cell RNA - SK-BR-3 [nTPM]":"250.9","Cell RNA - SK-MEL-30 [nTPM]":"116.9","Cell RNA - SuSa [nTPM]":"329.9","Cell RNA - T-47d [nTPM]":"349.5","Cell RNA - THP-1 [nTPM]":"130.3","Cell RNA - TIME [nTPM]":"241.6","Cell RNA - U-138 MG [nTPM]":"183.1","Cell RNA - U-2 OS [nTPM]":"210.7","Cell RNA - U-2197 [nTPM]":"266.4","Cell RNA - U-251 MG [nTPM]":"166.1","Cell RNA - U-266\/70 [nTPM]":"117.6","Cell RNA - U-266\/84 [nTPM]":"132.8","Cell RNA - U-698 [nTPM]":"286.3","Cell RNA - U-87 MG [nTPM]":"189.4","Cell RNA - U-937 [nTPM]":"150.8","Cell RNA - WM-115 [nTPM]":"224.9","Blood RNA - basophil [nTPM]":"31.0","Blood RNA - classical monocyte [nTPM]":"39.7","Blood RNA - eosinophil [nTPM]":"40.7","Blood RNA - gdT-cell [nTPM]":"39.4","Blood RNA - intermediate monocyte [nTPM]":"51.1","Blood RNA - MAIT T-cell [nTPM]":"34.0","Blood RNA - memory B-cell [nTPM]":"39.8","Blood RNA - memory CD4 T-cell [nTPM]":"31.8","Blood RNA - memory CD8 T-cell [nTPM]":"35.0","Blood RNA - myeloid DC [nTPM]":"43.2","Blood RNA - naive B-cell [nTPM]":"29.9","Blood RNA - naive CD4 T-cell [nTPM]":"24.7","Blood RNA - naive CD8 T-cell [nTPM]":"31.1","Blood RNA - neutrophil [nTPM]":"44.8","Blood RNA - NK-cell [nTPM]":"38.1","Blood RNA - non-classical monocyte [nTPM]":"49.7","Blood RNA - plasmacytoid DC [nTPM]":"29.3","Blood RNA - T-reg [nTPM]":"40.3","Blood RNA - total PBMC [nTPM]":"39.9","Brain RNA - amygdala [nTPM]":"102.9","Brain RNA - basal ganglia [nTPM]":"113.2","Brain RNA - cerebellum [nTPM]":"103.4","Brain RNA - cerebral cortex [nTPM]":"115.5","Brain RNA - hippocampal formation [nTPM]":"106.2","Brain RNA - hypothalamus [nTPM]":"102.0","Brain RNA - medulla oblongata [nTPM]":"106.9","Brain RNA - midbrain [nTPM]":"104.2","Brain RNA - pons [nTPM]":"109.3","Brain RNA - spinal cord [nTPM]":"94.4","Brain RNA - thalamus [nTPM]":"110.0","Brain RNA - white matter [nTPM]":"121.3","Single Cell Type RNA - Adipocytes [nTPM]":"37.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.7","Single Cell Type RNA - Astrocytes [nTPM]":"45.1","Single Cell Type RNA - B-cells [nTPM]":"37.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"38.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"55.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"24.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"51.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"50.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"82.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.3","Single Cell Type RNA - dendritic cells [nTPM]":"34.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"133.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"77.5","Single Cell Type RNA - Early spermatids [nTPM]":"29.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"84.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.3","Single Cell Type RNA - Endothelial cells [nTPM]":"40.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"57.5","Single Cell Type RNA - Erythroid cells [nTPM]":"33.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"90.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"68.7","Single Cell Type RNA - Fibroblasts [nTPM]":"45.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"74.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"97.5","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"60.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.5","Single Cell Type RNA - Hepatocytes [nTPM]":"51.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"60.0","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"78.6","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"49.0","Single Cell Type RNA - Langerhans cells [nTPM]":"37.8","Single Cell Type RNA - Late spermatids [nTPM]":"61.6","Single Cell Type RNA - Leydig cells [nTPM]":"42.3","Single Cell Type RNA - Macrophages [nTPM]":"51.4","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"57.7","Single Cell Type RNA - Muller glia cells [nTPM]":"20.7","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"147.9","Single Cell Type RNA - Paneth cells [nTPM]":"74.7","Single Cell Type RNA - Peritubular cells [nTPM]":"65.8","Single Cell Type RNA - Plasma cells [nTPM]":"44.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"55.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"82.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"61.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"56.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.5","Single Cell Type RNA - Spermatogonia [nTPM]":"34.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"51.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"42.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"71.1","Single Cell Type RNA - T-cells [nTPM]":"34.6","Single Cell Type RNA - Theca cells [nTPM]":"56.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"68.2","Single Cell Type RNA - Urothelial cells [nTPM]":"55.4"},{"Gene":"UBA5","Gene synonym":["FLJ23251","UBE1DC1"],"Ensembl":"ENSG00000081307","Gene description":"Ubiquitin like modifier activating enzyme 5","Uniprot":["Q9GZZ9"],"Chromosome":"3","Position":"132654446-132679794","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"418.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017235","HPA076042"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"43000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA017235":"AB_1858507","HPA076042":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.3","Tissue RNA - adrenal gland [nTPM]":"29.2","Tissue RNA - amygdala [nTPM]":"15.6","Tissue RNA - appendix [nTPM]":"18.6","Tissue RNA - basal ganglia [nTPM]":"17.5","Tissue RNA - bone marrow [nTPM]":"21.5","Tissue RNA - breast [nTPM]":"23.0","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"16.3","Tissue RNA - cervix [nTPM]":"18.0","Tissue RNA - choroid plexus [nTPM]":"30.9","Tissue RNA - colon [nTPM]":"21.5","Tissue RNA - duodenum [nTPM]":"24.0","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"30.4","Tissue RNA - esophagus [nTPM]":"17.2","Tissue RNA - fallopian tube [nTPM]":"16.6","Tissue RNA - gallbladder [nTPM]":"16.9","Tissue RNA - heart muscle [nTPM]":"23.8","Tissue RNA - hippocampal formation [nTPM]":"16.7","Tissue RNA - hypothalamus [nTPM]":"15.8","Tissue RNA - kidney [nTPM]":"31.3","Tissue RNA - liver [nTPM]":"31.8","Tissue RNA - lung [nTPM]":"17.7","Tissue RNA - lymph node [nTPM]":"22.4","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"52.1","Tissue RNA - parathyroid gland [nTPM]":"31.0","Tissue RNA - pituitary gland [nTPM]":"22.3","Tissue RNA - placenta [nTPM]":"25.8","Tissue RNA - pons [nTPM]":"14.1","Tissue RNA - prostate [nTPM]":"24.8","Tissue RNA - rectum [nTPM]":"22.6","Tissue RNA - retina [nTPM]":"25.2","Tissue RNA - salivary gland [nTPM]":"48.0","Tissue RNA - seminal vesicle [nTPM]":"20.2","Tissue RNA - skeletal muscle [nTPM]":"31.4","Tissue RNA - skin 1 [nTPM]":"22.0","Tissue RNA - small intestine [nTPM]":"24.8","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"21.1","Tissue RNA - stomach 1 [nTPM]":"26.7","Tissue RNA - testis [nTPM]":"17.0","Tissue RNA - thalamus [nTPM]":"14.2","Tissue RNA - thymus [nTPM]":"19.7","Tissue RNA - thyroid gland [nTPM]":"31.8","Tissue RNA - tongue [nTPM]":"24.4","Tissue RNA - tonsil [nTPM]":"24.9","Tissue RNA - urinary bladder [nTPM]":"17.2","Tissue RNA - vagina [nTPM]":"11.8","Tissue RNA - white matter [nTPM]":"16.5","Cell RNA - A-431 [nTPM]":"67.2","Cell RNA - A549 [nTPM]":"24.4","Cell RNA - AF22 [nTPM]":"42.1","Cell RNA - AN3-CA [nTPM]":"35.3","Cell RNA - ASC diff [nTPM]":"28.4","Cell RNA - ASC TERT1 [nTPM]":"31.9","Cell RNA - BEWO [nTPM]":"44.5","Cell RNA - BJ [nTPM]":"57.1","Cell RNA - BJ hTERT+ [nTPM]":"57.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.6","Cell RNA - CACO-2 [nTPM]":"44.9","Cell RNA - CAPAN-2 [nTPM]":"24.2","Cell RNA - Daudi [nTPM]":"52.1","Cell RNA - EFO-21 [nTPM]":"41.1","Cell RNA - fHDF\/TERT166 [nTPM]":"40.8","Cell RNA - GAMG [nTPM]":"23.3","Cell RNA - HaCaT [nTPM]":"39.6","Cell RNA - HAP1 [nTPM]":"41.6","Cell RNA - HBEC3-KT [nTPM]":"43.6","Cell RNA - HBF TERT88 [nTPM]":"49.5","Cell RNA - HDLM-2 [nTPM]":"51.3","Cell RNA - HEK 293 [nTPM]":"18.1","Cell RNA - HEL [nTPM]":"63.6","Cell RNA - HeLa [nTPM]":"39.6","Cell RNA - Hep G2 [nTPM]":"50.1","Cell RNA - HHSteC [nTPM]":"27.9","Cell RNA - HL-60 [nTPM]":"79.6","Cell RNA - HMC-1 [nTPM]":"36.7","Cell RNA - HSkMC [nTPM]":"28.0","Cell RNA - hTCEpi [nTPM]":"24.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.8","Cell RNA - hTERT-HME1 [nTPM]":"48.7","Cell RNA - hTERT-RPE1 [nTPM]":"31.8","Cell RNA - HUVEC TERT2 [nTPM]":"38.6","Cell RNA - JURKAT [nTPM]":"28.6","Cell RNA - K-562 [nTPM]":"41.0","Cell RNA - Karpas-707 [nTPM]":"76.2","Cell RNA - LHCN-M2 [nTPM]":"38.0","Cell RNA - MCF7 [nTPM]":"59.4","Cell RNA - MOLT-4 [nTPM]":"44.1","Cell RNA - NB-4 [nTPM]":"29.2","Cell RNA - NTERA-2 [nTPM]":"38.6","Cell RNA - OE19 [nTPM]":"56.3","Cell RNA - PC-3 [nTPM]":"22.9","Cell RNA - REH [nTPM]":"38.6","Cell RNA - RH-30 [nTPM]":"37.0","Cell RNA - RPMI-8226 [nTPM]":"99.8","Cell RNA - RPTEC TERT1 [nTPM]":"31.0","Cell RNA - RT4 [nTPM]":"50.9","Cell RNA - SCLC-21H [nTPM]":"40.2","Cell RNA - SH-SY5Y [nTPM]":"35.8","Cell RNA - SiHa [nTPM]":"33.5","Cell RNA - SK-BR-3 [nTPM]":"32.0","Cell RNA - SK-MEL-30 [nTPM]":"51.3","Cell RNA - SuSa [nTPM]":"37.8","Cell RNA - T-47d [nTPM]":"40.0","Cell RNA - THP-1 [nTPM]":"39.5","Cell RNA - TIME [nTPM]":"35.9","Cell RNA - U-138 MG [nTPM]":"36.7","Cell RNA - U-2 OS [nTPM]":"36.2","Cell RNA - U-2197 [nTPM]":"17.8","Cell RNA - U-251 MG [nTPM]":"29.8","Cell RNA - U-266\/70 [nTPM]":"71.7","Cell RNA - U-266\/84 [nTPM]":"51.8","Cell RNA - U-698 [nTPM]":"98.3","Cell RNA - U-87 MG [nTPM]":"40.9","Cell RNA - U-937 [nTPM]":"28.1","Cell RNA - WM-115 [nTPM]":"33.5","Blood RNA - basophil [nTPM]":"8.3","Blood RNA - classical monocyte [nTPM]":"7.1","Blood RNA - eosinophil [nTPM]":"7.0","Blood RNA - gdT-cell [nTPM]":"12.4","Blood RNA - intermediate monocyte [nTPM]":"8.2","Blood RNA - MAIT T-cell [nTPM]":"14.6","Blood RNA - memory B-cell [nTPM]":"15.1","Blood RNA - memory CD4 T-cell [nTPM]":"13.8","Blood RNA - memory CD8 T-cell [nTPM]":"19.1","Blood RNA - myeloid DC [nTPM]":"15.9","Blood RNA - naive B-cell [nTPM]":"10.2","Blood RNA - naive CD4 T-cell [nTPM]":"16.1","Blood RNA - naive CD8 T-cell [nTPM]":"16.3","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"26.0","Blood RNA - non-classical monocyte [nTPM]":"9.5","Blood RNA - plasmacytoid DC [nTPM]":"19.2","Blood RNA - T-reg [nTPM]":"15.5","Blood RNA - total PBMC [nTPM]":"10.5","Brain RNA - amygdala [nTPM]":"15.6","Brain RNA - basal ganglia [nTPM]":"17.5","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"16.3","Brain RNA - hippocampal formation [nTPM]":"16.7","Brain RNA - hypothalamus [nTPM]":"15.8","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"14.1","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"14.2","Brain RNA - white matter [nTPM]":"16.5","Single Cell Type RNA - Adipocytes [nTPM]":"23.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.9","Single Cell Type RNA - Astrocytes [nTPM]":"37.2","Single Cell Type RNA - B-cells [nTPM]":"24.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"22.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"36.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"24.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.0","Single Cell Type RNA - dendritic cells [nTPM]":"28.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"68.4","Single Cell Type RNA - Ductal cells [nTPM]":"30.3","Single Cell Type RNA - Early spermatids [nTPM]":"124.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.2","Single Cell Type RNA - Endothelial cells [nTPM]":"20.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.6","Single Cell Type RNA - Erythroid cells [nTPM]":"10.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.0","Single Cell Type RNA - Fibroblasts [nTPM]":"24.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.4","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"16.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"22.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.6","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.6","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"10.3","Single Cell Type RNA - Langerhans cells [nTPM]":"11.4","Single Cell Type RNA - Late spermatids [nTPM]":"418.2","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"13.9","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"21.6","Single Cell Type RNA - Muller glia cells [nTPM]":"26.1","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.2","Single Cell Type RNA - Paneth cells [nTPM]":"16.7","Single Cell Type RNA - Peritubular cells [nTPM]":"27.1","Single Cell Type RNA - Plasma cells [nTPM]":"85.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"43.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.6","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.2","Single Cell Type RNA - Spermatocytes [nTPM]":"49.4","Single Cell Type RNA - Spermatogonia [nTPM]":"23.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"99.7","Single Cell Type RNA - T-cells [nTPM]":"20.4","Single Cell Type RNA - Theca cells [nTPM]":"29.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.3","Single Cell Type RNA - Urothelial cells [nTPM]":"18.1"},{"Gene":"UBAP1","Gene synonym":["UBAP"],"Ensembl":"ENSG00000165006","Gene description":"Ubiquitin associated protein 1","Uniprot":["Q9NZ09"],"Chromosome":"9","Position":"34179005-34252523","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019804"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA019804":"AB_1858494"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.49e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"40.7","Tissue RNA - adrenal gland [nTPM]":"55.5","Tissue RNA - amygdala [nTPM]":"46.4","Tissue RNA - appendix [nTPM]":"24.5","Tissue RNA - basal ganglia [nTPM]":"47.1","Tissue RNA - bone marrow [nTPM]":"131.5","Tissue RNA - breast [nTPM]":"35.8","Tissue RNA - cerebellum [nTPM]":"48.0","Tissue RNA - cerebral cortex [nTPM]":"53.4","Tissue RNA - cervix [nTPM]":"45.0","Tissue RNA - choroid plexus [nTPM]":"46.4","Tissue RNA - colon [nTPM]":"38.5","Tissue RNA - duodenum [nTPM]":"22.3","Tissue RNA - endometrium 1 [nTPM]":"34.0","Tissue RNA - epididymis [nTPM]":"25.5","Tissue RNA - esophagus [nTPM]":"69.7","Tissue RNA - fallopian tube [nTPM]":"33.9","Tissue RNA - gallbladder [nTPM]":"30.4","Tissue RNA - heart muscle [nTPM]":"38.2","Tissue RNA - hippocampal formation [nTPM]":"45.6","Tissue RNA - hypothalamus [nTPM]":"48.2","Tissue RNA - kidney [nTPM]":"34.8","Tissue RNA - liver [nTPM]":"53.1","Tissue RNA - lung [nTPM]":"42.5","Tissue RNA - lymph node [nTPM]":"23.8","Tissue RNA - medulla oblongata [nTPM]":"48.5","Tissue RNA - midbrain [nTPM]":"48.5","Tissue RNA - ovary [nTPM]":"40.9","Tissue RNA - pancreas [nTPM]":"28.0","Tissue RNA - parathyroid gland [nTPM]":"34.4","Tissue RNA - pituitary gland [nTPM]":"25.6","Tissue RNA - placenta [nTPM]":"29.3","Tissue RNA - pons [nTPM]":"49.4","Tissue RNA - prostate [nTPM]":"30.4","Tissue RNA - rectum [nTPM]":"24.8","Tissue RNA - retina [nTPM]":"44.8","Tissue RNA - salivary gland [nTPM]":"29.6","Tissue RNA - seminal vesicle [nTPM]":"30.6","Tissue RNA - skeletal muscle [nTPM]":"110.0","Tissue RNA - skin 1 [nTPM]":"39.5","Tissue RNA - small intestine [nTPM]":"26.3","Tissue RNA - smooth muscle [nTPM]":"35.2","Tissue RNA - spinal cord [nTPM]":"46.3","Tissue RNA - spleen [nTPM]":"28.2","Tissue RNA - stomach 1 [nTPM]":"33.6","Tissue RNA - testis [nTPM]":"47.8","Tissue RNA - thalamus [nTPM]":"49.9","Tissue RNA - thymus [nTPM]":"31.6","Tissue RNA - thyroid gland [nTPM]":"25.6","Tissue RNA - tongue [nTPM]":"71.7","Tissue RNA - tonsil [nTPM]":"32.7","Tissue RNA - urinary bladder [nTPM]":"38.0","Tissue RNA - vagina [nTPM]":"45.8","Tissue RNA - white matter [nTPM]":"48.2","Cell RNA - A-431 [nTPM]":"56.7","Cell RNA - A549 [nTPM]":"31.7","Cell RNA - AF22 [nTPM]":"35.2","Cell RNA - AN3-CA [nTPM]":"38.4","Cell RNA - ASC diff [nTPM]":"63.6","Cell RNA - ASC TERT1 [nTPM]":"39.3","Cell RNA - BEWO [nTPM]":"29.8","Cell RNA - BJ [nTPM]":"44.4","Cell RNA - BJ hTERT+ [nTPM]":"61.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"65.6","Cell RNA - CACO-2 [nTPM]":"34.3","Cell RNA - CAPAN-2 [nTPM]":"23.0","Cell RNA - Daudi [nTPM]":"39.3","Cell RNA - EFO-21 [nTPM]":"19.5","Cell RNA - fHDF\/TERT166 [nTPM]":"66.5","Cell RNA - GAMG [nTPM]":"41.1","Cell RNA - HaCaT [nTPM]":"28.3","Cell RNA - HAP1 [nTPM]":"49.2","Cell RNA - HBEC3-KT [nTPM]":"69.5","Cell RNA - HBF TERT88 [nTPM]":"46.4","Cell RNA - HDLM-2 [nTPM]":"57.1","Cell RNA - HEK 293 [nTPM]":"22.3","Cell RNA - HEL [nTPM]":"35.1","Cell RNA - HeLa [nTPM]":"65.4","Cell RNA - Hep G2 [nTPM]":"35.5","Cell RNA - HHSteC [nTPM]":"57.8","Cell RNA - HL-60 [nTPM]":"39.3","Cell RNA - HMC-1 [nTPM]":"44.8","Cell RNA - HSkMC [nTPM]":"48.7","Cell RNA - hTCEpi [nTPM]":"113.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"57.5","Cell RNA - hTERT-HME1 [nTPM]":"75.0","Cell RNA - hTERT-RPE1 [nTPM]":"73.4","Cell RNA - HUVEC TERT2 [nTPM]":"54.4","Cell RNA - JURKAT [nTPM]":"37.9","Cell RNA - K-562 [nTPM]":"27.4","Cell RNA - Karpas-707 [nTPM]":"38.0","Cell RNA - LHCN-M2 [nTPM]":"45.7","Cell RNA - MCF7 [nTPM]":"23.7","Cell RNA - MOLT-4 [nTPM]":"36.5","Cell RNA - NB-4 [nTPM]":"55.0","Cell RNA - NTERA-2 [nTPM]":"38.2","Cell RNA - OE19 [nTPM]":"38.8","Cell RNA - PC-3 [nTPM]":"45.9","Cell RNA - REH [nTPM]":"32.6","Cell RNA - RH-30 [nTPM]":"24.8","Cell RNA - RPMI-8226 [nTPM]":"22.8","Cell RNA - RPTEC TERT1 [nTPM]":"104.2","Cell RNA - RT4 [nTPM]":"36.9","Cell RNA - SCLC-21H [nTPM]":"19.9","Cell RNA - SH-SY5Y [nTPM]":"28.1","Cell RNA - SiHa [nTPM]":"49.0","Cell RNA - SK-BR-3 [nTPM]":"50.2","Cell RNA - SK-MEL-30 [nTPM]":"22.5","Cell RNA - SuSa [nTPM]":"31.1","Cell RNA - T-47d [nTPM]":"24.6","Cell RNA - THP-1 [nTPM]":"38.5","Cell RNA - TIME [nTPM]":"39.2","Cell RNA - U-138 MG [nTPM]":"24.7","Cell RNA - U-2 OS [nTPM]":"38.0","Cell RNA - U-2197 [nTPM]":"37.4","Cell RNA - U-251 MG [nTPM]":"41.5","Cell RNA - U-266\/70 [nTPM]":"18.9","Cell RNA - U-266\/84 [nTPM]":"25.3","Cell RNA - U-698 [nTPM]":"41.0","Cell RNA - U-87 MG [nTPM]":"49.5","Cell RNA - U-937 [nTPM]":"31.5","Cell RNA - WM-115 [nTPM]":"74.2","Blood RNA - basophil [nTPM]":"26.8","Blood RNA - classical monocyte [nTPM]":"50.9","Blood RNA - eosinophil [nTPM]":"66.6","Blood RNA - gdT-cell [nTPM]":"38.0","Blood RNA - intermediate monocyte [nTPM]":"45.2","Blood RNA - MAIT T-cell [nTPM]":"65.8","Blood RNA - memory B-cell [nTPM]":"26.8","Blood RNA - memory CD4 T-cell [nTPM]":"38.1","Blood RNA - memory CD8 T-cell [nTPM]":"40.0","Blood RNA - myeloid DC [nTPM]":"47.1","Blood RNA - naive B-cell [nTPM]":"23.2","Blood RNA - naive CD4 T-cell [nTPM]":"36.3","Blood RNA - naive CD8 T-cell [nTPM]":"29.8","Blood RNA - neutrophil [nTPM]":"120.2","Blood RNA - NK-cell [nTPM]":"50.1","Blood RNA - non-classical monocyte [nTPM]":"41.0","Blood RNA - plasmacytoid DC [nTPM]":"26.7","Blood RNA - T-reg [nTPM]":"52.9","Blood RNA - total PBMC [nTPM]":"55.0","Brain RNA - amygdala [nTPM]":"46.4","Brain RNA - basal ganglia [nTPM]":"47.1","Brain RNA - cerebellum [nTPM]":"48.0","Brain RNA - cerebral cortex [nTPM]":"53.4","Brain RNA - hippocampal formation [nTPM]":"45.6","Brain RNA - hypothalamus [nTPM]":"48.2","Brain RNA - medulla oblongata [nTPM]":"48.5","Brain RNA - midbrain [nTPM]":"48.5","Brain RNA - pons [nTPM]":"49.4","Brain RNA - spinal cord [nTPM]":"46.3","Brain RNA - thalamus [nTPM]":"49.9","Brain RNA - white matter [nTPM]":"48.2","Single Cell Type RNA - Adipocytes [nTPM]":"21.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.0","Single Cell Type RNA - Astrocytes [nTPM]":"44.4","Single Cell Type RNA - B-cells [nTPM]":"22.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"66.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"15.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"33.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.2","Single Cell Type RNA - dendritic cells [nTPM]":"21.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"34.8","Single Cell Type RNA - Early spermatids [nTPM]":"77.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"56.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.2","Single Cell Type RNA - Endothelial cells [nTPM]":"21.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.1","Single Cell Type RNA - Erythroid cells [nTPM]":"50.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"40.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.4","Single Cell Type RNA - Fibroblasts [nTPM]":"31.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"90.0","Single Cell Type RNA - granulocytes [nTPM]":"25.9","Single Cell Type RNA - Granulosa cells [nTPM]":"15.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"25.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.5","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"21.4","Single Cell Type RNA - Langerhans cells [nTPM]":"39.8","Single Cell Type RNA - Late spermatids [nTPM]":"62.9","Single Cell Type RNA - Leydig cells [nTPM]":"29.2","Single Cell Type RNA - Macrophages [nTPM]":"38.2","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"23.1","Single Cell Type RNA - Muller glia cells [nTPM]":"26.0","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.3","Single Cell Type RNA - Paneth cells [nTPM]":"23.0","Single Cell Type RNA - Peritubular cells [nTPM]":"42.5","Single Cell Type RNA - Plasma cells [nTPM]":"25.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"47.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.5","Single Cell Type RNA - Spermatocytes [nTPM]":"51.0","Single Cell Type RNA - Spermatogonia [nTPM]":"22.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"54.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"89.6","Single Cell Type RNA - T-cells [nTPM]":"28.6","Single Cell Type RNA - Theca cells [nTPM]":"20.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.8","Single Cell Type RNA - Urothelial cells [nTPM]":"70.9"},{"Gene":"UBIAD1","Gene synonym":["SCCD","TERE1"],"Ensembl":"ENSG00000120942","Gene description":"UbiA prenyltransferase domain containing 1","Uniprot":["Q9Y5Z9"],"Chromosome":"1","Position":"11273198-11296049","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Menaquinone biosynthesis","Ubiquinone biosynthesis"],"Molecular function":["Prenyltransferase","Transferase"],"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044862"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA044862":"AB_2679117"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.80e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"7.5","Tissue RNA - bone marrow [nTPM]":"7.6","Tissue RNA - breast [nTPM]":"8.3","Tissue RNA - cerebellum [nTPM]":"6.9","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"2.3","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"8.4","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"8.2","Tissue RNA - hippocampal formation [nTPM]":"5.2","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"6.5","Tissue RNA - liver [nTPM]":"10.1","Tissue RNA - lung [nTPM]":"6.1","Tissue RNA - lymph node [nTPM]":"10.2","Tissue RNA - medulla oblongata [nTPM]":"7.5","Tissue RNA - midbrain [nTPM]":"7.5","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"10.8","Tissue RNA - parathyroid gland [nTPM]":"10.0","Tissue RNA - pituitary gland [nTPM]":"5.8","Tissue RNA - placenta [nTPM]":"6.4","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"7.1","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"8.0","Tissue RNA - salivary gland [nTPM]":"7.0","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"17.7","Tissue RNA - skin 1 [nTPM]":"8.1","Tissue RNA - small intestine [nTPM]":"6.4","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"7.1","Tissue RNA - stomach 1 [nTPM]":"7.2","Tissue RNA - testis [nTPM]":"9.2","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"11.9","Tissue RNA - thyroid gland [nTPM]":"7.7","Tissue RNA - tongue [nTPM]":"13.8","Tissue RNA - tonsil [nTPM]":"10.5","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"5.6","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"14.5","Cell RNA - A549 [nTPM]":"14.1","Cell RNA - AF22 [nTPM]":"11.0","Cell RNA - AN3-CA [nTPM]":"21.3","Cell RNA - ASC diff [nTPM]":"8.0","Cell RNA - ASC TERT1 [nTPM]":"7.4","Cell RNA - BEWO [nTPM]":"14.8","Cell RNA - BJ [nTPM]":"15.6","Cell RNA - BJ hTERT+ [nTPM]":"12.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.9","Cell RNA - CACO-2 [nTPM]":"16.4","Cell RNA - CAPAN-2 [nTPM]":"13.1","Cell RNA - Daudi [nTPM]":"28.5","Cell RNA - EFO-21 [nTPM]":"15.6","Cell RNA - fHDF\/TERT166 [nTPM]":"11.1","Cell RNA - GAMG [nTPM]":"15.4","Cell RNA - HaCaT [nTPM]":"19.5","Cell RNA - HAP1 [nTPM]":"28.1","Cell RNA - HBEC3-KT [nTPM]":"18.7","Cell RNA - HBF TERT88 [nTPM]":"19.9","Cell RNA - HDLM-2 [nTPM]":"20.0","Cell RNA - HEK 293 [nTPM]":"24.1","Cell RNA - HEL [nTPM]":"19.1","Cell RNA - HeLa [nTPM]":"14.5","Cell RNA - Hep G2 [nTPM]":"22.0","Cell RNA - HHSteC [nTPM]":"14.5","Cell RNA - HL-60 [nTPM]":"29.5","Cell RNA - HMC-1 [nTPM]":"15.9","Cell RNA - HSkMC [nTPM]":"11.2","Cell RNA - hTCEpi [nTPM]":"24.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.2","Cell RNA - hTERT-HME1 [nTPM]":"26.3","Cell RNA - hTERT-RPE1 [nTPM]":"8.7","Cell RNA - HUVEC TERT2 [nTPM]":"12.2","Cell RNA - JURKAT [nTPM]":"25.8","Cell RNA - K-562 [nTPM]":"23.1","Cell RNA - Karpas-707 [nTPM]":"22.9","Cell RNA - LHCN-M2 [nTPM]":"11.2","Cell RNA - MCF7 [nTPM]":"14.8","Cell RNA - MOLT-4 [nTPM]":"19.1","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"13.3","Cell RNA - OE19 [nTPM]":"27.1","Cell RNA - PC-3 [nTPM]":"20.7","Cell RNA - REH [nTPM]":"18.0","Cell RNA - RH-30 [nTPM]":"24.6","Cell RNA - RPMI-8226 [nTPM]":"34.6","Cell RNA - RPTEC TERT1 [nTPM]":"12.7","Cell RNA - RT4 [nTPM]":"9.5","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"14.5","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"16.3","Cell RNA - SK-MEL-30 [nTPM]":"21.5","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"12.1","Cell RNA - THP-1 [nTPM]":"15.3","Cell RNA - TIME [nTPM]":"10.2","Cell RNA - U-138 MG [nTPM]":"14.4","Cell RNA - U-2 OS [nTPM]":"15.5","Cell RNA - U-2197 [nTPM]":"15.1","Cell RNA - U-251 MG [nTPM]":"20.5","Cell RNA - U-266\/70 [nTPM]":"18.6","Cell RNA - U-266\/84 [nTPM]":"27.9","Cell RNA - U-698 [nTPM]":"52.4","Cell RNA - U-87 MG [nTPM]":"9.2","Cell RNA - U-937 [nTPM]":"38.3","Cell RNA - WM-115 [nTPM]":"18.3","Blood RNA - basophil [nTPM]":"11.5","Blood RNA - classical monocyte [nTPM]":"12.8","Blood RNA - eosinophil [nTPM]":"19.5","Blood RNA - gdT-cell [nTPM]":"24.3","Blood RNA - intermediate monocyte [nTPM]":"17.5","Blood RNA - MAIT T-cell [nTPM]":"27.3","Blood RNA - memory B-cell [nTPM]":"45.3","Blood RNA - memory CD4 T-cell [nTPM]":"32.5","Blood RNA - memory CD8 T-cell [nTPM]":"24.8","Blood RNA - myeloid DC [nTPM]":"16.9","Blood RNA - naive B-cell [nTPM]":"42.1","Blood RNA - naive CD4 T-cell [nTPM]":"48.5","Blood RNA - naive CD8 T-cell [nTPM]":"33.3","Blood RNA - neutrophil [nTPM]":"3.9","Blood RNA - NK-cell [nTPM]":"20.5","Blood RNA - non-classical monocyte [nTPM]":"15.6","Blood RNA - plasmacytoid DC [nTPM]":"21.1","Blood RNA - T-reg [nTPM]":"33.8","Blood RNA - total PBMC [nTPM]":"22.2","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"7.5","Brain RNA - cerebellum [nTPM]":"6.9","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"5.2","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"7.5","Brain RNA - midbrain [nTPM]":"7.5","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"9.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.6","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"19.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"18.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.6","Single Cell Type RNA - dendritic cells [nTPM]":"17.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"10.8","Single Cell Type RNA - Early spermatids [nTPM]":"34.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"13.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.7","Single Cell Type RNA - Fibroblasts [nTPM]":"11.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.6","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"19.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.7","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"14.1","Single Cell Type RNA - Late spermatids [nTPM]":"23.1","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"9.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"7.1","Single Cell Type RNA - Muller glia cells [nTPM]":"9.5","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.0","Single Cell Type RNA - Paneth cells [nTPM]":"5.3","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.4","Single Cell Type RNA - Spermatocytes [nTPM]":"24.7","Single Cell Type RNA - Spermatogonia [nTPM]":"15.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.9","Single Cell Type RNA - T-cells [nTPM]":"14.4","Single Cell Type RNA - Theca cells [nTPM]":"12.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.3"},{"Gene":"UBQLN2","Gene synonym":["Chap1","CHAP1\/DSK2","Dsk2","LIC-2","N4BP4","PLIC-2","PLIC2","RIHFB2157"],"Ensembl":"ENSG00000188021","Gene description":"Ubiquilin 2","Uniprot":["Q9UHD9"],"Chromosome":"X","Position":"56563627-56567868","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006431","CAB013481"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB013481":"AB_2533341","HPA006431":"AB_1078707"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-3"},"Tissue RNA - adipose tissue [nTPM]":"13.8","Tissue RNA - adrenal gland [nTPM]":"20.2","Tissue RNA - amygdala [nTPM]":"24.9","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"26.8","Tissue RNA - bone marrow [nTPM]":"11.1","Tissue RNA - breast [nTPM]":"12.1","Tissue RNA - cerebellum [nTPM]":"19.7","Tissue RNA - cerebral cortex [nTPM]":"30.6","Tissue RNA - cervix [nTPM]":"15.9","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"15.7","Tissue RNA - duodenum [nTPM]":"11.2","Tissue RNA - endometrium 1 [nTPM]":"16.6","Tissue RNA - epididymis [nTPM]":"15.9","Tissue RNA - esophagus [nTPM]":"18.7","Tissue RNA - fallopian tube [nTPM]":"17.5","Tissue RNA - gallbladder [nTPM]":"14.5","Tissue RNA - heart muscle [nTPM]":"21.6","Tissue RNA - hippocampal formation [nTPM]":"27.4","Tissue RNA - hypothalamus [nTPM]":"25.5","Tissue RNA - kidney [nTPM]":"13.5","Tissue RNA - liver [nTPM]":"19.4","Tissue RNA - lung [nTPM]":"13.8","Tissue RNA - lymph node [nTPM]":"18.4","Tissue RNA - medulla oblongata [nTPM]":"20.2","Tissue RNA - midbrain [nTPM]":"20.4","Tissue RNA - ovary [nTPM]":"25.7","Tissue RNA - pancreas [nTPM]":"10.5","Tissue RNA - parathyroid gland [nTPM]":"23.6","Tissue RNA - pituitary gland [nTPM]":"16.3","Tissue RNA - placenta [nTPM]":"15.8","Tissue RNA - pons [nTPM]":"22.1","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"12.1","Tissue RNA - retina [nTPM]":"22.2","Tissue RNA - salivary gland [nTPM]":"14.4","Tissue RNA - seminal vesicle [nTPM]":"20.0","Tissue RNA - skeletal muscle [nTPM]":"28.0","Tissue RNA - skin 1 [nTPM]":"13.6","Tissue RNA - small intestine [nTPM]":"12.4","Tissue RNA - smooth muscle [nTPM]":"18.4","Tissue RNA - spinal cord [nTPM]":"21.3","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"13.1","Tissue RNA - testis [nTPM]":"4.4","Tissue RNA - thalamus [nTPM]":"22.6","Tissue RNA - thymus [nTPM]":"18.9","Tissue RNA - thyroid gland [nTPM]":"20.7","Tissue RNA - tongue [nTPM]":"22.8","Tissue RNA - tonsil [nTPM]":"18.6","Tissue RNA - urinary bladder [nTPM]":"18.6","Tissue RNA - vagina [nTPM]":"11.1","Tissue RNA - white matter [nTPM]":"25.5","Cell RNA - A-431 [nTPM]":"36.3","Cell RNA - A549 [nTPM]":"26.5","Cell RNA - AF22 [nTPM]":"25.9","Cell RNA - AN3-CA [nTPM]":"30.6","Cell RNA - ASC diff [nTPM]":"58.3","Cell RNA - ASC TERT1 [nTPM]":"37.0","Cell RNA - BEWO [nTPM]":"16.3","Cell RNA - BJ [nTPM]":"28.6","Cell RNA - BJ hTERT+ [nTPM]":"33.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.2","Cell RNA - CACO-2 [nTPM]":"14.9","Cell RNA - CAPAN-2 [nTPM]":"16.6","Cell RNA - Daudi [nTPM]":"27.6","Cell RNA - EFO-21 [nTPM]":"30.5","Cell RNA - fHDF\/TERT166 [nTPM]":"34.0","Cell RNA - GAMG [nTPM]":"32.9","Cell RNA - HaCaT [nTPM]":"20.7","Cell RNA - HAP1 [nTPM]":"50.0","Cell RNA - HBEC3-KT [nTPM]":"31.9","Cell RNA - HBF TERT88 [nTPM]":"25.3","Cell RNA - HDLM-2 [nTPM]":"43.0","Cell RNA - HEK 293 [nTPM]":"30.1","Cell RNA - HEL [nTPM]":"11.2","Cell RNA - HeLa [nTPM]":"34.2","Cell RNA - Hep G2 [nTPM]":"15.9","Cell RNA - HHSteC [nTPM]":"30.6","Cell RNA - HL-60 [nTPM]":"22.1","Cell RNA - HMC-1 [nTPM]":"23.7","Cell RNA - HSkMC [nTPM]":"34.7","Cell RNA - hTCEpi [nTPM]":"39.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.3","Cell RNA - hTERT-HME1 [nTPM]":"24.6","Cell RNA - hTERT-RPE1 [nTPM]":"30.3","Cell RNA - HUVEC TERT2 [nTPM]":"18.7","Cell RNA - JURKAT [nTPM]":"17.6","Cell RNA - K-562 [nTPM]":"13.3","Cell RNA - Karpas-707 [nTPM]":"29.5","Cell RNA - LHCN-M2 [nTPM]":"33.6","Cell RNA - MCF7 [nTPM]":"16.9","Cell RNA - MOLT-4 [nTPM]":"28.5","Cell RNA - NB-4 [nTPM]":"19.2","Cell RNA - NTERA-2 [nTPM]":"21.7","Cell RNA - OE19 [nTPM]":"11.6","Cell RNA - PC-3 [nTPM]":"31.1","Cell RNA - REH [nTPM]":"25.3","Cell RNA - RH-30 [nTPM]":"33.7","Cell RNA - RPMI-8226 [nTPM]":"26.3","Cell RNA - RPTEC TERT1 [nTPM]":"42.8","Cell RNA - RT4 [nTPM]":"27.9","Cell RNA - SCLC-21H [nTPM]":"31.9","Cell RNA - SH-SY5Y [nTPM]":"29.9","Cell RNA - SiHa [nTPM]":"41.3","Cell RNA - SK-BR-3 [nTPM]":"18.1","Cell RNA - SK-MEL-30 [nTPM]":"17.4","Cell RNA - SuSa [nTPM]":"45.2","Cell RNA - T-47d [nTPM]":"30.4","Cell RNA - THP-1 [nTPM]":"16.1","Cell RNA - TIME [nTPM]":"21.2","Cell RNA - U-138 MG [nTPM]":"22.2","Cell RNA - U-2 OS [nTPM]":"22.5","Cell RNA - U-2197 [nTPM]":"32.4","Cell RNA - U-251 MG [nTPM]":"17.5","Cell RNA - U-266\/70 [nTPM]":"11.1","Cell RNA - U-266\/84 [nTPM]":"14.8","Cell RNA - U-698 [nTPM]":"18.9","Cell RNA - U-87 MG [nTPM]":"24.9","Cell RNA - U-937 [nTPM]":"23.1","Cell RNA - WM-115 [nTPM]":"19.3","Blood RNA - basophil [nTPM]":"50.0","Blood RNA - classical monocyte [nTPM]":"23.6","Blood RNA - eosinophil [nTPM]":"24.1","Blood RNA - gdT-cell [nTPM]":"15.1","Blood RNA - intermediate monocyte [nTPM]":"31.1","Blood RNA - MAIT T-cell [nTPM]":"17.1","Blood RNA - memory B-cell [nTPM]":"7.8","Blood RNA - memory CD4 T-cell [nTPM]":"22.9","Blood RNA - memory CD8 T-cell [nTPM]":"17.7","Blood RNA - myeloid DC [nTPM]":"17.8","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"30.3","Blood RNA - naive CD8 T-cell [nTPM]":"18.9","Blood RNA - neutrophil [nTPM]":"20.4","Blood RNA - NK-cell [nTPM]":"20.9","Blood RNA - non-classical monocyte [nTPM]":"34.2","Blood RNA - plasmacytoid DC [nTPM]":"6.5","Blood RNA - T-reg [nTPM]":"23.5","Blood RNA - total PBMC [nTPM]":"20.3","Brain RNA - amygdala [nTPM]":"24.9","Brain RNA - basal ganglia [nTPM]":"26.8","Brain RNA - cerebellum [nTPM]":"19.7","Brain RNA - cerebral cortex [nTPM]":"30.6","Brain RNA - hippocampal formation [nTPM]":"27.4","Brain RNA - hypothalamus [nTPM]":"25.5","Brain RNA - medulla oblongata [nTPM]":"20.2","Brain RNA - midbrain [nTPM]":"20.4","Brain RNA - pons [nTPM]":"22.1","Brain RNA - spinal cord [nTPM]":"21.3","Brain RNA - thalamus [nTPM]":"22.6","Brain RNA - white matter [nTPM]":"25.5","Single Cell Type RNA - Adipocytes [nTPM]":"13.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"30.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"41.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"42.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"25.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.8","Single Cell Type RNA - dendritic cells [nTPM]":"15.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"20.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.7","Single Cell Type RNA - Endothelial cells [nTPM]":"18.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.2","Single Cell Type RNA - Erythroid cells [nTPM]":"18.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.7","Single Cell Type RNA - Fibroblasts [nTPM]":"27.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.7","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"14.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"20.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.7","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.3","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"30.7","Single Cell Type RNA - Langerhans cells [nTPM]":"25.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"21.1","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"35.9","Single Cell Type RNA - Muller glia cells [nTPM]":"22.3","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.9","Single Cell Type RNA - Paneth cells [nTPM]":"12.7","Single Cell Type RNA - Peritubular cells [nTPM]":"36.5","Single Cell Type RNA - Plasma cells [nTPM]":"23.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"40.0","Single Cell Type RNA - T-cells [nTPM]":"28.7","Single Cell Type RNA - Theca cells [nTPM]":"12.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.3","Single Cell Type RNA - Urothelial cells [nTPM]":"35.6"},{"Gene":"UBTF","Gene synonym":["NOR-90","UBF","UBF1","UBF2"],"Ensembl":"ENSG00000108312","Gene description":"Upstream binding transcription factor","Uniprot":["P17480"],"Chromosome":"17","Position":"44205033-44221626","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004611","HPA006385"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"CAB004611":"AB_671403","HPA006385":"AB_1080447"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Tissue RNA - adipose tissue [nTPM]":"34.8","Tissue RNA - adrenal gland [nTPM]":"36.5","Tissue RNA - amygdala [nTPM]":"36.2","Tissue RNA - appendix [nTPM]":"44.8","Tissue RNA - basal ganglia [nTPM]":"33.7","Tissue RNA - bone marrow [nTPM]":"54.9","Tissue RNA - breast [nTPM]":"35.4","Tissue RNA - cerebellum [nTPM]":"38.2","Tissue RNA - cerebral cortex [nTPM]":"37.1","Tissue RNA - cervix [nTPM]":"50.6","Tissue RNA - choroid plexus [nTPM]":"30.1","Tissue RNA - colon [nTPM]":"49.4","Tissue RNA - duodenum [nTPM]":"33.6","Tissue RNA - endometrium 1 [nTPM]":"50.8","Tissue RNA - epididymis [nTPM]":"27.5","Tissue RNA - esophagus [nTPM]":"41.8","Tissue RNA - fallopian tube [nTPM]":"41.9","Tissue RNA - gallbladder [nTPM]":"32.5","Tissue RNA - heart muscle [nTPM]":"38.8","Tissue RNA - hippocampal formation [nTPM]":"35.5","Tissue RNA - hypothalamus [nTPM]":"32.7","Tissue RNA - kidney [nTPM]":"38.1","Tissue RNA - liver [nTPM]":"36.1","Tissue RNA - lung [nTPM]":"32.3","Tissue RNA - lymph node [nTPM]":"67.6","Tissue RNA - medulla oblongata [nTPM]":"34.0","Tissue RNA - midbrain [nTPM]":"34.5","Tissue RNA - ovary [nTPM]":"41.6","Tissue RNA - pancreas [nTPM]":"41.4","Tissue RNA - parathyroid gland [nTPM]":"38.2","Tissue RNA - pituitary gland [nTPM]":"33.8","Tissue RNA - placenta [nTPM]":"29.2","Tissue RNA - pons [nTPM]":"32.2","Tissue RNA - prostate [nTPM]":"41.6","Tissue RNA - rectum [nTPM]":"28.2","Tissue RNA - retina [nTPM]":"23.1","Tissue RNA - salivary gland [nTPM]":"37.7","Tissue RNA - seminal vesicle [nTPM]":"40.8","Tissue RNA - skeletal muscle [nTPM]":"63.7","Tissue RNA - skin 1 [nTPM]":"47.4","Tissue RNA - small intestine [nTPM]":"42.5","Tissue RNA - smooth muscle [nTPM]":"36.3","Tissue RNA - spinal cord [nTPM]":"31.6","Tissue RNA - spleen [nTPM]":"49.8","Tissue RNA - stomach 1 [nTPM]":"34.7","Tissue RNA - testis [nTPM]":"20.8","Tissue RNA - thalamus [nTPM]":"34.9","Tissue RNA - thymus [nTPM]":"73.6","Tissue RNA - thyroid gland [nTPM]":"46.4","Tissue RNA - tongue [nTPM]":"36.6","Tissue RNA - tonsil [nTPM]":"51.7","Tissue RNA - urinary bladder [nTPM]":"45.1","Tissue RNA - vagina [nTPM]":"41.8","Tissue RNA - white matter [nTPM]":"35.0","Cell RNA - A-431 [nTPM]":"69.1","Cell RNA - A549 [nTPM]":"104.3","Cell RNA - AF22 [nTPM]":"77.3","Cell RNA - AN3-CA [nTPM]":"93.2","Cell RNA - ASC diff [nTPM]":"49.6","Cell RNA - ASC TERT1 [nTPM]":"56.5","Cell RNA - BEWO [nTPM]":"72.3","Cell RNA - BJ [nTPM]":"70.6","Cell RNA - BJ hTERT+ [nTPM]":"46.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"70.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.0","Cell RNA - CACO-2 [nTPM]":"50.7","Cell RNA - CAPAN-2 [nTPM]":"54.8","Cell RNA - Daudi [nTPM]":"250.0","Cell RNA - EFO-21 [nTPM]":"69.3","Cell RNA - fHDF\/TERT166 [nTPM]":"65.3","Cell RNA - GAMG [nTPM]":"51.9","Cell RNA - HaCaT [nTPM]":"63.6","Cell RNA - HAP1 [nTPM]":"99.1","Cell RNA - HBEC3-KT [nTPM]":"59.2","Cell RNA - HBF TERT88 [nTPM]":"57.9","Cell RNA - HDLM-2 [nTPM]":"145.3","Cell RNA - HEK 293 [nTPM]":"109.5","Cell RNA - HEL [nTPM]":"100.5","Cell RNA - HeLa [nTPM]":"73.8","Cell RNA - Hep G2 [nTPM]":"83.7","Cell RNA - HHSteC [nTPM]":"32.5","Cell RNA - HL-60 [nTPM]":"192.1","Cell RNA - HMC-1 [nTPM]":"85.7","Cell RNA - HSkMC [nTPM]":"56.9","Cell RNA - hTCEpi [nTPM]":"52.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.6","Cell RNA - hTERT-HME1 [nTPM]":"65.6","Cell RNA - hTERT-RPE1 [nTPM]":"67.2","Cell RNA - HUVEC TERT2 [nTPM]":"58.9","Cell RNA - JURKAT [nTPM]":"108.8","Cell RNA - K-562 [nTPM]":"117.4","Cell RNA - Karpas-707 [nTPM]":"75.9","Cell RNA - LHCN-M2 [nTPM]":"58.9","Cell RNA - MCF7 [nTPM]":"113.7","Cell RNA - MOLT-4 [nTPM]":"188.3","Cell RNA - NB-4 [nTPM]":"75.0","Cell RNA - NTERA-2 [nTPM]":"73.7","Cell RNA - OE19 [nTPM]":"46.6","Cell RNA - PC-3 [nTPM]":"81.6","Cell RNA - REH [nTPM]":"184.0","Cell RNA - RH-30 [nTPM]":"104.3","Cell RNA - RPMI-8226 [nTPM]":"112.0","Cell RNA - RPTEC TERT1 [nTPM]":"40.4","Cell RNA - RT4 [nTPM]":"54.5","Cell RNA - SCLC-21H [nTPM]":"119.5","Cell RNA - SH-SY5Y [nTPM]":"90.3","Cell RNA - SiHa [nTPM]":"70.4","Cell RNA - SK-BR-3 [nTPM]":"62.2","Cell RNA - SK-MEL-30 [nTPM]":"54.2","Cell RNA - SuSa [nTPM]":"47.9","Cell RNA - T-47d [nTPM]":"89.9","Cell RNA - THP-1 [nTPM]":"120.8","Cell RNA - TIME [nTPM]":"75.5","Cell RNA - U-138 MG [nTPM]":"109.9","Cell RNA - U-2 OS [nTPM]":"133.1","Cell RNA - U-2197 [nTPM]":"65.1","Cell RNA - U-251 MG [nTPM]":"95.0","Cell RNA - U-266\/70 [nTPM]":"66.6","Cell RNA - U-266\/84 [nTPM]":"61.7","Cell RNA - U-698 [nTPM]":"151.1","Cell RNA - U-87 MG [nTPM]":"64.8","Cell RNA - U-937 [nTPM]":"86.0","Cell RNA - WM-115 [nTPM]":"100.1","Blood RNA - basophil [nTPM]":"9.6","Blood RNA - classical monocyte [nTPM]":"5.7","Blood RNA - eosinophil [nTPM]":"6.1","Blood RNA - gdT-cell [nTPM]":"15.5","Blood RNA - intermediate monocyte [nTPM]":"6.3","Blood RNA - MAIT T-cell [nTPM]":"16.7","Blood RNA - memory B-cell [nTPM]":"11.7","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"16.2","Blood RNA - myeloid DC [nTPM]":"6.7","Blood RNA - naive B-cell [nTPM]":"14.1","Blood RNA - naive CD4 T-cell [nTPM]":"12.2","Blood RNA - naive CD8 T-cell [nTPM]":"13.1","Blood RNA - neutrophil [nTPM]":"9.7","Blood RNA - NK-cell [nTPM]":"15.7","Blood RNA - non-classical monocyte [nTPM]":"11.6","Blood RNA - plasmacytoid DC [nTPM]":"12.7","Blood RNA - T-reg [nTPM]":"10.0","Blood RNA - total PBMC [nTPM]":"11.3","Brain RNA - amygdala [nTPM]":"36.2","Brain RNA - basal ganglia [nTPM]":"33.7","Brain RNA - cerebellum [nTPM]":"38.2","Brain RNA - cerebral cortex [nTPM]":"37.1","Brain RNA - hippocampal formation [nTPM]":"35.5","Brain RNA - hypothalamus [nTPM]":"32.7","Brain RNA - medulla oblongata [nTPM]":"34.0","Brain RNA - midbrain [nTPM]":"34.5","Brain RNA - pons [nTPM]":"32.2","Brain RNA - spinal cord [nTPM]":"31.6","Brain RNA - thalamus [nTPM]":"34.9","Brain RNA - white matter [nTPM]":"35.0","Single Cell Type RNA - Adipocytes [nTPM]":"41.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"42.1","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"57.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"57.5","Single Cell Type RNA - Bipolar cells [nTPM]":"88.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"32.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.9","Single Cell Type RNA - dendritic cells [nTPM]":"60.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"27.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"57.7","Single Cell Type RNA - Endothelial cells [nTPM]":"42.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"47.3","Single Cell Type RNA - Erythroid cells [nTPM]":"61.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"40.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.7","Single Cell Type RNA - Fibroblasts [nTPM]":"38.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.1","Single Cell Type RNA - granulocytes [nTPM]":"31.7","Single Cell Type RNA - Granulosa cells [nTPM]":"43.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.5","Single Cell Type RNA - Hepatocytes [nTPM]":"26.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.9","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.5","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.4","Single Cell Type RNA - Langerhans cells [nTPM]":"13.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"36.7","Single Cell Type RNA - Macrophages [nTPM]":"27.4","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"38.1","Single Cell Type RNA - Muller glia cells [nTPM]":"33.9","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.1","Single Cell Type RNA - Paneth cells [nTPM]":"30.7","Single Cell Type RNA - Peritubular cells [nTPM]":"50.8","Single Cell Type RNA - Plasma cells [nTPM]":"42.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"57.6","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"48.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.9","Single Cell Type RNA - Spermatocytes [nTPM]":"5.3","Single Cell Type RNA - Spermatogonia [nTPM]":"44.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"52.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.7","Single Cell Type RNA - T-cells [nTPM]":"53.1","Single Cell Type RNA - Theca cells [nTPM]":"40.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.8","Single Cell Type RNA - Urothelial cells [nTPM]":"11.8"},{"Gene":"UCHL1","Gene synonym":["PARK5","PGP9.5","Uch-L1"],"Ensembl":"ENSG00000154277","Gene description":"Ubiquitin C-terminal hydrolase L1","Uniprot":["P09936"],"Chromosome":"4","Position":"41256413-41268455","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"692.7","pituitary gland":"285.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"115.8","Distal tubular cells":"258.2","Excitatory neurons":"147.1","Horizontal cells":"146.4","Inhibitory neurons":"118.4","Spermatogonia":"88.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"129.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"1142.2","SCLC-21H":"1160.6","U-251 MG":"1162.6","U-266\/84":"1138.4","U-87 MG":"1209.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002580","HPA005993","CAB079024"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"500000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB002580":"AB_563981","CAB079024":null,"HPA005993":"AB_1858560"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.08e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.93e-4"},"Tissue RNA - adipose tissue [nTPM]":"30.1","Tissue RNA - adrenal gland [nTPM]":"104.4","Tissue RNA - amygdala [nTPM]":"211.4","Tissue RNA - appendix [nTPM]":"19.2","Tissue RNA - basal ganglia [nTPM]":"188.8","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"83.4","Tissue RNA - cerebral cortex [nTPM]":"342.7","Tissue RNA - cervix [nTPM]":"18.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"49.0","Tissue RNA - duodenum [nTPM]":"9.0","Tissue RNA - endometrium 1 [nTPM]":"13.2","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"3.3","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"12.3","Tissue RNA - heart muscle [nTPM]":"26.9","Tissue RNA - hippocampal formation [nTPM]":"229.7","Tissue RNA - hypothalamus [nTPM]":"692.7","Tissue RNA - kidney [nTPM]":"62.7","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"8.2","Tissue RNA - lymph node [nTPM]":"12.9","Tissue RNA - medulla oblongata [nTPM]":"255.7","Tissue RNA - midbrain [nTPM]":"205.2","Tissue RNA - ovary [nTPM]":"35.6","Tissue RNA - pancreas [nTPM]":"11.6","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"285.4","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"446.7","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"38.3","Tissue RNA - salivary gland [nTPM]":"3.7","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"27.5","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"18.9","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"122.2","Tissue RNA - spleen [nTPM]":"2.7","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"16.5","Tissue RNA - thalamus [nTPM]":"150.3","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"9.8","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"7.3","Tissue RNA - urinary bladder [nTPM]":"31.7","Tissue RNA - vagina [nTPM]":"29.1","Tissue RNA - white matter [nTPM]":"231.2","Cell RNA - A-431 [nTPM]":"3.3","Cell RNA - A549 [nTPM]":"712.8","Cell RNA - AF22 [nTPM]":"146.8","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"18.9","Cell RNA - ASC TERT1 [nTPM]":"19.7","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"681.4","Cell RNA - BJ hTERT+ [nTPM]":"352.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"236.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"243.4","Cell RNA - CACO-2 [nTPM]":"149.0","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1142.2","Cell RNA - fHDF\/TERT166 [nTPM]":"384.4","Cell RNA - GAMG [nTPM]":"356.7","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"262.8","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"116.4","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"97.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"6.9","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"529.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"127.4","Cell RNA - hTCEpi [nTPM]":"3.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"197.9","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"413.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"2.3","Cell RNA - LHCN-M2 [nTPM]":"122.6","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"12.3","Cell RNA - NTERA-2 [nTPM]":"435.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"714.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"297.2","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"386.3","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"1160.6","Cell RNA - SH-SY5Y [nTPM]":"765.7","Cell RNA - SiHa [nTPM]":"5.1","Cell RNA - SK-BR-3 [nTPM]":"2.8","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"165.4","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"5.0","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"16.8","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"1162.6","Cell RNA - U-266\/70 [nTPM]":"583.1","Cell RNA - U-266\/84 [nTPM]":"1138.4","Cell RNA - U-698 [nTPM]":"3.1","Cell RNA - U-87 MG [nTPM]":"1209.3","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"211.4","Brain RNA - basal ganglia [nTPM]":"188.8","Brain RNA - cerebellum [nTPM]":"83.4","Brain RNA - cerebral cortex [nTPM]":"342.7","Brain RNA - hippocampal formation [nTPM]":"229.7","Brain RNA - hypothalamus [nTPM]":"692.7","Brain RNA - medulla oblongata [nTPM]":"255.7","Brain RNA - midbrain [nTPM]":"205.2","Brain RNA - pons [nTPM]":"446.7","Brain RNA - spinal cord [nTPM]":"122.2","Brain RNA - thalamus [nTPM]":"150.3","Brain RNA - white matter [nTPM]":"231.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"29.0","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"25.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"115.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"258.2","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.8","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"147.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"35.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"46.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"146.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"118.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.0","Single Cell Type RNA - Leydig cells [nTPM]":"37.0","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"21.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"55.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"54.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"9.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"61.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.7","Single Cell Type RNA - Spermatocytes [nTPM]":"10.4","Single Cell Type RNA - Spermatogonia [nTPM]":"88.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"20.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"UGDH","Gene synonym":[],"Ensembl":"ENSG00000109814","Gene description":"UDP-glucose 6-dehydrogenase","Uniprot":["O60701"],"Chromosome":"4","Position":"39498755-39528311","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Allosteric enzyme","Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"137.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"345.5","Hepatocytes":"231.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"509.6","Hep G2":"595.9","U-2197":"375.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034444","HPA036656","HPA036657"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB034444":"AB_2019602","HPA036656":"AB_10671706","HPA036657":"AB_10672360"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.51e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.5","Tissue RNA - adrenal gland [nTPM]":"27.8","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"29.5","Tissue RNA - basal ganglia [nTPM]":"7.3","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"32.0","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"9.2","Tissue RNA - cervix [nTPM]":"31.5","Tissue RNA - choroid plexus [nTPM]":"18.1","Tissue RNA - colon [nTPM]":"96.5","Tissue RNA - duodenum [nTPM]":"45.3","Tissue RNA - endometrium 1 [nTPM]":"29.1","Tissue RNA - epididymis [nTPM]":"10.6","Tissue RNA - esophagus [nTPM]":"34.1","Tissue RNA - fallopian tube [nTPM]":"29.6","Tissue RNA - gallbladder [nTPM]":"40.5","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"8.3","Tissue RNA - kidney [nTPM]":"37.5","Tissue RNA - liver [nTPM]":"137.7","Tissue RNA - lung [nTPM]":"19.0","Tissue RNA - lymph node [nTPM]":"13.3","Tissue RNA - medulla oblongata [nTPM]":"7.4","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"30.0","Tissue RNA - pancreas [nTPM]":"33.7","Tissue RNA - parathyroid gland [nTPM]":"23.1","Tissue RNA - pituitary gland [nTPM]":"7.8","Tissue RNA - placenta [nTPM]":"38.4","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"35.6","Tissue RNA - rectum [nTPM]":"73.3","Tissue RNA - retina [nTPM]":"14.3","Tissue RNA - salivary gland [nTPM]":"16.8","Tissue RNA - seminal vesicle [nTPM]":"14.0","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"9.9","Tissue RNA - small intestine [nTPM]":"41.1","Tissue RNA - smooth muscle [nTPM]":"23.5","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"11.5","Tissue RNA - stomach 1 [nTPM]":"47.4","Tissue RNA - testis [nTPM]":"6.8","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"27.8","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"54.4","Tissue RNA - vagina [nTPM]":"17.1","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"36.0","Cell RNA - A549 [nTPM]":"509.6","Cell RNA - AF22 [nTPM]":"58.4","Cell RNA - AN3-CA [nTPM]":"76.2","Cell RNA - ASC diff [nTPM]":"181.5","Cell RNA - ASC TERT1 [nTPM]":"185.3","Cell RNA - BEWO [nTPM]":"51.3","Cell RNA - BJ [nTPM]":"102.7","Cell RNA - BJ hTERT+ [nTPM]":"113.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"94.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"84.8","Cell RNA - CACO-2 [nTPM]":"76.2","Cell RNA - CAPAN-2 [nTPM]":"115.5","Cell RNA - Daudi [nTPM]":"25.4","Cell RNA - EFO-21 [nTPM]":"63.0","Cell RNA - fHDF\/TERT166 [nTPM]":"133.3","Cell RNA - GAMG [nTPM]":"94.5","Cell RNA - HaCaT [nTPM]":"33.5","Cell RNA - HAP1 [nTPM]":"56.0","Cell RNA - HBEC3-KT [nTPM]":"29.5","Cell RNA - HBF TERT88 [nTPM]":"95.8","Cell RNA - HDLM-2 [nTPM]":"32.1","Cell RNA - HEK 293 [nTPM]":"13.0","Cell RNA - HEL [nTPM]":"26.2","Cell RNA - HeLa [nTPM]":"65.4","Cell RNA - Hep G2 [nTPM]":"595.9","Cell RNA - HHSteC [nTPM]":"72.7","Cell RNA - HL-60 [nTPM]":"34.1","Cell RNA - HMC-1 [nTPM]":"25.3","Cell RNA - HSkMC [nTPM]":"64.4","Cell RNA - hTCEpi [nTPM]":"14.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"160.2","Cell RNA - hTERT-HME1 [nTPM]":"49.8","Cell RNA - hTERT-RPE1 [nTPM]":"78.9","Cell RNA - HUVEC TERT2 [nTPM]":"59.3","Cell RNA - JURKAT [nTPM]":"20.9","Cell RNA - K-562 [nTPM]":"34.1","Cell RNA - Karpas-707 [nTPM]":"17.3","Cell RNA - LHCN-M2 [nTPM]":"67.9","Cell RNA - MCF7 [nTPM]":"89.8","Cell RNA - MOLT-4 [nTPM]":"29.4","Cell RNA - NB-4 [nTPM]":"34.4","Cell RNA - NTERA-2 [nTPM]":"53.1","Cell RNA - OE19 [nTPM]":"194.0","Cell RNA - PC-3 [nTPM]":"46.4","Cell RNA - REH [nTPM]":"48.3","Cell RNA - RH-30 [nTPM]":"95.0","Cell RNA - RPMI-8226 [nTPM]":"22.0","Cell RNA - RPTEC TERT1 [nTPM]":"53.7","Cell RNA - RT4 [nTPM]":"120.0","Cell RNA - SCLC-21H [nTPM]":"31.2","Cell RNA - SH-SY5Y [nTPM]":"46.7","Cell RNA - SiHa [nTPM]":"69.2","Cell RNA - SK-BR-3 [nTPM]":"37.9","Cell RNA - SK-MEL-30 [nTPM]":"45.3","Cell RNA - SuSa [nTPM]":"41.4","Cell RNA - T-47d [nTPM]":"21.0","Cell RNA - THP-1 [nTPM]":"27.0","Cell RNA - TIME [nTPM]":"85.9","Cell RNA - U-138 MG [nTPM]":"97.9","Cell RNA - U-2 OS [nTPM]":"49.1","Cell RNA - U-2197 [nTPM]":"375.8","Cell RNA - U-251 MG [nTPM]":"54.2","Cell RNA - U-266\/70 [nTPM]":"42.1","Cell RNA - U-266\/84 [nTPM]":"33.3","Cell RNA - U-698 [nTPM]":"23.3","Cell RNA - U-87 MG [nTPM]":"86.9","Cell RNA - U-937 [nTPM]":"25.8","Cell RNA - WM-115 [nTPM]":"56.6","Blood RNA - basophil [nTPM]":"30.0","Blood RNA - classical monocyte [nTPM]":"20.9","Blood RNA - eosinophil [nTPM]":"19.7","Blood RNA - gdT-cell [nTPM]":"23.2","Blood RNA - intermediate monocyte [nTPM]":"18.4","Blood RNA - MAIT T-cell [nTPM]":"37.8","Blood RNA - memory B-cell [nTPM]":"18.8","Blood RNA - memory CD4 T-cell [nTPM]":"18.8","Blood RNA - memory CD8 T-cell [nTPM]":"24.9","Blood RNA - myeloid DC [nTPM]":"19.0","Blood RNA - naive B-cell [nTPM]":"18.4","Blood RNA - naive CD4 T-cell [nTPM]":"16.1","Blood RNA - naive CD8 T-cell [nTPM]":"19.4","Blood RNA - neutrophil [nTPM]":"3.8","Blood RNA - NK-cell [nTPM]":"42.3","Blood RNA - non-classical monocyte [nTPM]":"11.2","Blood RNA - plasmacytoid DC [nTPM]":"22.5","Blood RNA - T-reg [nTPM]":"13.5","Blood RNA - total PBMC [nTPM]":"18.8","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"7.3","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"9.2","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"8.3","Brain RNA - medulla oblongata [nTPM]":"7.4","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"19.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.6","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"14.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"116.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"73.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"7.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"115.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"62.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"25.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.3","Single Cell Type RNA - dendritic cells [nTPM]":"12.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"207.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"70.5","Single Cell Type RNA - Ductal cells [nTPM]":"54.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"78.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"53.8","Single Cell Type RNA - Endothelial cells [nTPM]":"25.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"113.3","Single Cell Type RNA - Erythroid cells [nTPM]":"9.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"345.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"78.8","Single Cell Type RNA - Fibroblasts [nTPM]":"145.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"184.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"64.8","Single Cell Type RNA - granulocytes [nTPM]":"35.5","Single Cell Type RNA - Granulosa cells [nTPM]":"11.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"231.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.8","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"114.5","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"20.2","Single Cell Type RNA - Langerhans cells [nTPM]":"33.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"33.2","Single Cell Type RNA - Macrophages [nTPM]":"12.7","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"19.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"46.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"195.8","Single Cell Type RNA - Paneth cells [nTPM]":"112.2","Single Cell Type RNA - Peritubular cells [nTPM]":"29.0","Single Cell Type RNA - Plasma cells [nTPM]":"21.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"127.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"81.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"79.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"65.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"57.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"102.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.0","Single Cell Type RNA - T-cells [nTPM]":"11.7","Single Cell Type RNA - Theca cells [nTPM]":"12.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"152.4","Single Cell Type RNA - Urothelial cells [nTPM]":"86.4"},{"Gene":"UGP2","Gene synonym":["SVUGP2","UGP1","UGPP1"],"Ensembl":"ENSG00000169764","Gene description":"UDP-glucose pyrophosphorylase 2","Uniprot":["Q16851"],"Chromosome":"2","Position":"63840952-63891562","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"858.6","tongue":"756.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"849.9","Hepatocytes":"559.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"417.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034696","HPA034697","HPA064836"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Centrosome","Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA034696":"AB_10670171","HPA034697":"AB_2674287","HPA064836":"AB_2685365"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.50e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"267.3","Tissue RNA - adrenal gland [nTPM]":"72.0","Tissue RNA - amygdala [nTPM]":"79.8","Tissue RNA - appendix [nTPM]":"65.8","Tissue RNA - basal ganglia [nTPM]":"89.3","Tissue RNA - bone marrow [nTPM]":"40.1","Tissue RNA - breast [nTPM]":"119.7","Tissue RNA - cerebellum [nTPM]":"72.7","Tissue RNA - cerebral cortex [nTPM]":"109.8","Tissue RNA - cervix [nTPM]":"65.9","Tissue RNA - choroid plexus [nTPM]":"78.8","Tissue RNA - colon [nTPM]":"177.9","Tissue RNA - duodenum [nTPM]":"66.0","Tissue RNA - endometrium 1 [nTPM]":"75.2","Tissue RNA - epididymis [nTPM]":"50.6","Tissue RNA - esophagus [nTPM]":"97.5","Tissue RNA - fallopian tube [nTPM]":"68.9","Tissue RNA - gallbladder [nTPM]":"60.7","Tissue RNA - heart muscle [nTPM]":"232.5","Tissue RNA - hippocampal formation [nTPM]":"87.9","Tissue RNA - hypothalamus [nTPM]":"81.4","Tissue RNA - kidney [nTPM]":"105.4","Tissue RNA - liver [nTPM]":"858.6","Tissue RNA - lung [nTPM]":"65.4","Tissue RNA - lymph node [nTPM]":"65.7","Tissue RNA - medulla oblongata [nTPM]":"77.7","Tissue RNA - midbrain [nTPM]":"77.0","Tissue RNA - ovary [nTPM]":"47.0","Tissue RNA - pancreas [nTPM]":"74.4","Tissue RNA - parathyroid gland [nTPM]":"113.3","Tissue RNA - pituitary gland [nTPM]":"49.8","Tissue RNA - placenta [nTPM]":"137.8","Tissue RNA - pons [nTPM]":"77.6","Tissue RNA - prostate [nTPM]":"57.4","Tissue RNA - rectum [nTPM]":"159.3","Tissue RNA - retina [nTPM]":"36.8","Tissue RNA - salivary gland [nTPM]":"92.9","Tissue RNA - seminal vesicle [nTPM]":"66.2","Tissue RNA - skeletal muscle [nTPM]":"498.0","Tissue RNA - skin 1 [nTPM]":"59.1","Tissue RNA - small intestine [nTPM]":"67.6","Tissue RNA - smooth muscle [nTPM]":"78.5","Tissue RNA - spinal cord [nTPM]":"73.2","Tissue RNA - spleen [nTPM]":"50.8","Tissue RNA - stomach 1 [nTPM]":"69.5","Tissue RNA - testis [nTPM]":"38.3","Tissue RNA - thalamus [nTPM]":"83.3","Tissue RNA - thymus [nTPM]":"106.2","Tissue RNA - thyroid gland [nTPM]":"64.5","Tissue RNA - tongue [nTPM]":"756.1","Tissue RNA - tonsil [nTPM]":"73.7","Tissue RNA - urinary bladder [nTPM]":"88.4","Tissue RNA - vagina [nTPM]":"63.7","Tissue RNA - white matter [nTPM]":"91.8","Cell RNA - A-431 [nTPM]":"122.3","Cell RNA - A549 [nTPM]":"77.6","Cell RNA - AF22 [nTPM]":"63.1","Cell RNA - AN3-CA [nTPM]":"42.0","Cell RNA - ASC diff [nTPM]":"176.1","Cell RNA - ASC TERT1 [nTPM]":"222.4","Cell RNA - BEWO [nTPM]":"220.6","Cell RNA - BJ [nTPM]":"129.1","Cell RNA - BJ hTERT+ [nTPM]":"116.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"82.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.4","Cell RNA - CACO-2 [nTPM]":"170.0","Cell RNA - CAPAN-2 [nTPM]":"104.5","Cell RNA - Daudi [nTPM]":"149.5","Cell RNA - EFO-21 [nTPM]":"48.3","Cell RNA - fHDF\/TERT166 [nTPM]":"165.6","Cell RNA - GAMG [nTPM]":"79.9","Cell RNA - HaCaT [nTPM]":"57.4","Cell RNA - HAP1 [nTPM]":"73.4","Cell RNA - HBEC3-KT [nTPM]":"102.6","Cell RNA - HBF TERT88 [nTPM]":"137.0","Cell RNA - HDLM-2 [nTPM]":"99.2","Cell RNA - HEK 293 [nTPM]":"35.7","Cell RNA - HEL [nTPM]":"86.5","Cell RNA - HeLa [nTPM]":"50.4","Cell RNA - Hep G2 [nTPM]":"117.9","Cell RNA - HHSteC [nTPM]":"87.0","Cell RNA - HL-60 [nTPM]":"79.1","Cell RNA - HMC-1 [nTPM]":"73.9","Cell RNA - HSkMC [nTPM]":"148.1","Cell RNA - hTCEpi [nTPM]":"175.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"76.1","Cell RNA - hTERT-HME1 [nTPM]":"80.3","Cell RNA - hTERT-RPE1 [nTPM]":"108.4","Cell RNA - HUVEC TERT2 [nTPM]":"119.4","Cell RNA - JURKAT [nTPM]":"38.9","Cell RNA - K-562 [nTPM]":"48.2","Cell RNA - Karpas-707 [nTPM]":"58.1","Cell RNA - LHCN-M2 [nTPM]":"327.8","Cell RNA - MCF7 [nTPM]":"56.7","Cell RNA - MOLT-4 [nTPM]":"104.6","Cell RNA - NB-4 [nTPM]":"75.2","Cell RNA - NTERA-2 [nTPM]":"122.9","Cell RNA - OE19 [nTPM]":"207.7","Cell RNA - PC-3 [nTPM]":"50.1","Cell RNA - REH [nTPM]":"80.4","Cell RNA - RH-30 [nTPM]":"117.9","Cell RNA - RPMI-8226 [nTPM]":"84.5","Cell RNA - RPTEC TERT1 [nTPM]":"147.4","Cell RNA - RT4 [nTPM]":"77.7","Cell RNA - SCLC-21H [nTPM]":"36.5","Cell RNA - SH-SY5Y [nTPM]":"29.6","Cell RNA - SiHa [nTPM]":"103.3","Cell RNA - SK-BR-3 [nTPM]":"149.8","Cell RNA - SK-MEL-30 [nTPM]":"64.3","Cell RNA - SuSa [nTPM]":"162.6","Cell RNA - T-47d [nTPM]":"51.7","Cell RNA - THP-1 [nTPM]":"59.2","Cell RNA - TIME [nTPM]":"144.3","Cell RNA - U-138 MG [nTPM]":"84.4","Cell RNA - U-2 OS [nTPM]":"125.9","Cell RNA - U-2197 [nTPM]":"113.8","Cell RNA - U-251 MG [nTPM]":"90.5","Cell RNA - U-266\/70 [nTPM]":"101.3","Cell RNA - U-266\/84 [nTPM]":"51.4","Cell RNA - U-698 [nTPM]":"174.9","Cell RNA - U-87 MG [nTPM]":"99.2","Cell RNA - U-937 [nTPM]":"122.7","Cell RNA - WM-115 [nTPM]":"225.7","Blood RNA - basophil [nTPM]":"417.1","Blood RNA - classical monocyte [nTPM]":"33.0","Blood RNA - eosinophil [nTPM]":"53.1","Blood RNA - gdT-cell [nTPM]":"48.0","Blood RNA - intermediate monocyte [nTPM]":"40.7","Blood RNA - MAIT T-cell [nTPM]":"51.8","Blood RNA - memory B-cell [nTPM]":"33.0","Blood RNA - memory CD4 T-cell [nTPM]":"53.6","Blood RNA - memory CD8 T-cell [nTPM]":"50.1","Blood RNA - myeloid DC [nTPM]":"27.9","Blood RNA - naive B-cell [nTPM]":"31.8","Blood RNA - naive CD4 T-cell [nTPM]":"57.6","Blood RNA - naive CD8 T-cell [nTPM]":"53.6","Blood RNA - neutrophil [nTPM]":"45.4","Blood RNA - NK-cell [nTPM]":"70.0","Blood RNA - non-classical monocyte [nTPM]":"39.5","Blood RNA - plasmacytoid DC [nTPM]":"29.7","Blood RNA - T-reg [nTPM]":"127.2","Blood RNA - total PBMC [nTPM]":"62.0","Brain RNA - amygdala [nTPM]":"79.8","Brain RNA - basal ganglia [nTPM]":"89.3","Brain RNA - cerebellum [nTPM]":"72.7","Brain RNA - cerebral cortex [nTPM]":"109.8","Brain RNA - hippocampal formation [nTPM]":"87.9","Brain RNA - hypothalamus [nTPM]":"81.4","Brain RNA - medulla oblongata [nTPM]":"77.7","Brain RNA - midbrain [nTPM]":"77.0","Brain RNA - pons [nTPM]":"77.6","Brain RNA - spinal cord [nTPM]":"73.2","Brain RNA - thalamus [nTPM]":"83.3","Brain RNA - white matter [nTPM]":"91.8","Single Cell Type RNA - Adipocytes [nTPM]":"73.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.0","Single Cell Type RNA - Astrocytes [nTPM]":"107.4","Single Cell Type RNA - B-cells [nTPM]":"65.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"75.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"87.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"245.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Bipolar cells [nTPM]":"49.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"360.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"87.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"264.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"104.4","Single Cell Type RNA - Club cells [nTPM]":"171.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"414.3","Single Cell Type RNA - dendritic cells [nTPM]":"81.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"849.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"242.6","Single Cell Type RNA - Ductal cells [nTPM]":"140.6","Single Cell Type RNA - Early spermatids [nTPM]":"91.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"53.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"106.3","Single Cell Type RNA - Endothelial cells [nTPM]":"69.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.5","Single Cell Type RNA - Erythroid cells [nTPM]":"56.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"86.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"103.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"445.5","Single Cell Type RNA - Fibroblasts [nTPM]":"159.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"79.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.5","Single Cell Type RNA - granulocytes [nTPM]":"67.8","Single Cell Type RNA - Granulosa cells [nTPM]":"42.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.5","Single Cell Type RNA - Hepatocytes [nTPM]":"559.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"120.9","Single Cell Type RNA - Horizontal cells [nTPM]":"87.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"78.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"179.8","Single Cell Type RNA - Ionocytes [nTPM]":"144.5","Single Cell Type RNA - Kupffer cells [nTPM]":"102.4","Single Cell Type RNA - Langerhans cells [nTPM]":"90.2","Single Cell Type RNA - Late spermatids [nTPM]":"86.1","Single Cell Type RNA - Leydig cells [nTPM]":"79.2","Single Cell Type RNA - Macrophages [nTPM]":"89.1","Single Cell Type RNA - Melanocytes [nTPM]":"96.0","Single Cell Type RNA - Microglial cells [nTPM]":"62.8","Single Cell Type RNA - monocytes [nTPM]":"139.7","Single Cell Type RNA - Muller glia cells [nTPM]":"58.8","Single Cell Type RNA - NK-cells [nTPM]":"154.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"79.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"91.6","Single Cell Type RNA - Paneth cells [nTPM]":"313.9","Single Cell Type RNA - Peritubular cells [nTPM]":"77.5","Single Cell Type RNA - Plasma cells [nTPM]":"60.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"81.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"176.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"284.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"139.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"57.3","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"50.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"129.2","Single Cell Type RNA - Spermatocytes [nTPM]":"84.9","Single Cell Type RNA - Spermatogonia [nTPM]":"54.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"50.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"57.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"472.8","Single Cell Type RNA - T-cells [nTPM]":"143.1","Single Cell Type RNA - Theca cells [nTPM]":"90.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"189.5","Single Cell Type RNA - Urothelial cells [nTPM]":"109.1"},{"Gene":"UNC45B","Gene synonym":["CMYA4","UNC45"],"Ensembl":"ENSG00000141161","Gene description":"Unc-45 myosin chaperone B","Uniprot":["Q8IWX7"],"Chromosome":"17","Position":"35147817-35189345","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Myogenesis"],"Molecular function":["Chaperone","Developmental protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"59","RNA tissue specific nTPM":{"heart muscle":"100.3","skeletal muscle":"196.6","tongue":"151.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"201.8","Late spermatids":"59.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"head and neck cancer":"0.9","testis cancer":"1.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"1.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"BEWO":"1.7","HSkMC":"2.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017861"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017861":"AB_1847012"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"100.3","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"196.6","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"151.9","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"201.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"24.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"3.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"59.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"USH1C","Gene synonym":["AIE-75","DFNB18","harmonin","NY-CO-37","NY-CO-38","PDZ-73","PDZ73","PDZD7C"],"Ensembl":"ENSG00000006611","Gene description":"USH1 protein network component harmonin","Uniprot":["Q9Y6N9"],"Chromosome":"11","Position":"17493895-17544416","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Hearing"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Deafness","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"97.8","kidney":"54.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"190.0","Muller glia cells":"163.6","Paneth cells":"203.0","Proximal enterocytes":"430.7","Proximal tubular cells":"190.3","Undifferentiated cells":"115.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"colorectal cancer":"34.5","pancreatic cancer":"18.8","renal cancer":"29.4","stomach cancer":"15.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"CACO-2":"60.6","HeLa":"21.8","OE19":"57.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013690","HPA027398","HPA027492","HPA028033"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB013690":null,"HPA027398":"AB_10601775","HPA027492":"AB_10601898","HPA028033":"AB_10601782"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.41e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"5.9","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"51.5","Tissue RNA - duodenum [nTPM]":"97.8","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"25.9","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"9.0","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"54.0","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"5.7","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"6.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"7.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"48.3","Tissue RNA - retina [nTPM]":"19.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"96.5","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"26.7","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"60.6","Cell RNA - CAPAN-2 [nTPM]":"8.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"21.8","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"57.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"9.0","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"5.7","Brain RNA - pons [nTPM]":"7.0","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"18.3","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"190.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"20.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"64.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"53.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"92.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"163.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"56.0","Single Cell Type RNA - Paneth cells [nTPM]":"203.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"430.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"190.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"115.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"USH1G","Gene synonym":["ANKS4A","FLJ33924","Sans"],"Ensembl":"ENSG00000182040","Gene description":"USH1 protein network component sans","Uniprot":["Q495M9"],"Chromosome":"17","Position":"74916083-74923256","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"7.8","skin 1":"2.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"8.2","Late spermatids":"17.9","Muller glia cells":"11.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"1.8","hTCEpi":"1.6","K-562":"1.3","MCF7":"2.0","OE19":"1.9"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"12","RNA mouse brain regional specific nTPM":{"olfactory bulb":"9.9"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024360"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024360":"AB_1858660"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"7.8","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.8","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.9","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"17.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"USH2A","Gene synonym":["RP39","USH2"],"Ensembl":"ENSG00000042781","Gene description":"Usherin","Uniprot":["O75445"],"Chromosome":"1","Position":"215622891-216423448","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Hearing","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"liver":"7.0","retina":"19.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"202.3","Early spermatids":"49.3","Rod photoreceptor cells":"165.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"7.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"19.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"202.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"49.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"12.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"165.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"USP45","Gene synonym":["MGC14793"],"Ensembl":"ENSG00000123552","Gene description":"Ubiquitin specific peptidase 45","Uniprot":["Q70EL2"],"Chromosome":"6","Position":"99432325-99521728","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"53.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"47.1","Inhibitory neurons":"44.4","Oligodendrocytes":"39.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"53.5"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029602","HPA029604"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029602":"AB_10600418","HPA029604":"AB_10602283"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.1","Tissue RNA - adrenal gland [nTPM]":"4.4","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"5.8","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"53.5","Tissue RNA - cerebral cortex [nTPM]":"9.4","Tissue RNA - cervix [nTPM]":"4.3","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"5.3","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"5.1","Tissue RNA - epididymis [nTPM]":"4.8","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"3.7","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"4.5","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"5.2","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"6.7","Tissue RNA - retina [nTPM]":"6.7","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"6.0","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"6.2","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"4.3","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"5.9","Cell RNA - A549 [nTPM]":"4.0","Cell RNA - AF22 [nTPM]":"8.1","Cell RNA - AN3-CA [nTPM]":"11.2","Cell RNA - ASC diff [nTPM]":"14.3","Cell RNA - ASC TERT1 [nTPM]":"13.5","Cell RNA - BEWO [nTPM]":"8.7","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.7","Cell RNA - CACO-2 [nTPM]":"8.2","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"15.2","Cell RNA - EFO-21 [nTPM]":"7.3","Cell RNA - fHDF\/TERT166 [nTPM]":"10.3","Cell RNA - GAMG [nTPM]":"11.9","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"12.1","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"13.9","Cell RNA - HDLM-2 [nTPM]":"12.2","Cell RNA - HEK 293 [nTPM]":"12.0","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"8.4","Cell RNA - Hep G2 [nTPM]":"6.7","Cell RNA - HHSteC [nTPM]":"11.4","Cell RNA - HL-60 [nTPM]":"14.2","Cell RNA - HMC-1 [nTPM]":"8.3","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"7.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.2","Cell RNA - hTERT-HME1 [nTPM]":"15.5","Cell RNA - hTERT-RPE1 [nTPM]":"10.7","Cell RNA - HUVEC TERT2 [nTPM]":"15.4","Cell RNA - JURKAT [nTPM]":"13.8","Cell RNA - K-562 [nTPM]":"37.2","Cell RNA - Karpas-707 [nTPM]":"14.8","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"5.5","Cell RNA - MOLT-4 [nTPM]":"4.5","Cell RNA - NB-4 [nTPM]":"13.3","Cell RNA - NTERA-2 [nTPM]":"12.8","Cell RNA - OE19 [nTPM]":"9.1","Cell RNA - PC-3 [nTPM]":"8.9","Cell RNA - REH [nTPM]":"6.8","Cell RNA - RH-30 [nTPM]":"5.9","Cell RNA - RPMI-8226 [nTPM]":"8.9","Cell RNA - RPTEC TERT1 [nTPM]":"13.8","Cell RNA - RT4 [nTPM]":"6.8","Cell RNA - SCLC-21H [nTPM]":"11.3","Cell RNA - SH-SY5Y [nTPM]":"9.2","Cell RNA - SiHa [nTPM]":"7.0","Cell RNA - SK-BR-3 [nTPM]":"9.1","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"10.0","Cell RNA - T-47d [nTPM]":"4.9","Cell RNA - THP-1 [nTPM]":"6.8","Cell RNA - TIME [nTPM]":"15.5","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"7.1","Cell RNA - U-2197 [nTPM]":"8.1","Cell RNA - U-251 MG [nTPM]":"15.5","Cell RNA - U-266\/70 [nTPM]":"6.3","Cell RNA - U-266\/84 [nTPM]":"6.2","Cell RNA - U-698 [nTPM]":"29.1","Cell RNA - U-87 MG [nTPM]":"9.8","Cell RNA - U-937 [nTPM]":"13.1","Cell RNA - WM-115 [nTPM]":"10.1","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"4.2","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"6.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"3.6","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"5.8","Brain RNA - cerebellum [nTPM]":"53.5","Brain RNA - cerebral cortex [nTPM]":"9.4","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"6.2","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"13.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"10.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - dendritic cells [nTPM]":"7.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"15.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.3","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.6","Single Cell Type RNA - Fibroblasts [nTPM]":"7.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.3","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"5.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"4.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"44.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"10.2","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"4.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"10.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"6.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"5.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.3","Single Cell Type RNA - Urothelial cells [nTPM]":"6.9"},{"Gene":"VAMP1","Gene synonym":["SYB1","VAMP-1"],"Ensembl":"ENSG00000139190","Gene description":"Vesicle associated membrane protein 1","Uniprot":["P23763"],"Chromosome":"12","Position":"6462237-6470677","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"192.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"20.0","Excitatory neurons":"22.6","Inhibitory neurons":"25.0","Oligodendrocytes":"26.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"U-698":"200.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002779","CAB016119","CAB079000"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002779":null,"CAB016119":"AB_628309","CAB079000":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.37e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.97e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"18.9","Tissue RNA - amygdala [nTPM]":"45.3","Tissue RNA - appendix [nTPM]":"21.9","Tissue RNA - basal ganglia [nTPM]":"60.6","Tissue RNA - bone marrow [nTPM]":"63.4","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"102.1","Tissue RNA - cerebral cortex [nTPM]":"179.8","Tissue RNA - cervix [nTPM]":"19.6","Tissue RNA - choroid plexus [nTPM]":"30.6","Tissue RNA - colon [nTPM]":"35.4","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"20.9","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"12.5","Tissue RNA - fallopian tube [nTPM]":"22.4","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"40.1","Tissue RNA - hypothalamus [nTPM]":"85.4","Tissue RNA - kidney [nTPM]":"16.1","Tissue RNA - liver [nTPM]":"18.6","Tissue RNA - lung [nTPM]":"15.2","Tissue RNA - lymph node [nTPM]":"39.7","Tissue RNA - medulla oblongata [nTPM]":"192.8","Tissue RNA - midbrain [nTPM]":"89.2","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"10.4","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"12.8","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"163.5","Tissue RNA - prostate [nTPM]":"24.1","Tissue RNA - rectum [nTPM]":"11.9","Tissue RNA - retina [nTPM]":"35.7","Tissue RNA - salivary gland [nTPM]":"14.5","Tissue RNA - seminal vesicle [nTPM]":"9.9","Tissue RNA - skeletal muscle [nTPM]":"10.0","Tissue RNA - skin 1 [nTPM]":"8.9","Tissue RNA - small intestine [nTPM]":"33.0","Tissue RNA - smooth muscle [nTPM]":"10.3","Tissue RNA - spinal cord [nTPM]":"93.3","Tissue RNA - spleen [nTPM]":"42.2","Tissue RNA - stomach 1 [nTPM]":"17.5","Tissue RNA - testis [nTPM]":"11.4","Tissue RNA - thalamus [nTPM]":"106.3","Tissue RNA - thymus [nTPM]":"12.8","Tissue RNA - thyroid gland [nTPM]":"30.8","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"35.9","Tissue RNA - urinary bladder [nTPM]":"21.4","Tissue RNA - vagina [nTPM]":"18.5","Tissue RNA - white matter [nTPM]":"93.9","Cell RNA - A-431 [nTPM]":"3.0","Cell RNA - A549 [nTPM]":"11.0","Cell RNA - AF22 [nTPM]":"5.8","Cell RNA - AN3-CA [nTPM]":"8.1","Cell RNA - ASC diff [nTPM]":"16.7","Cell RNA - ASC TERT1 [nTPM]":"19.1","Cell RNA - BEWO [nTPM]":"7.1","Cell RNA - BJ [nTPM]":"5.4","Cell RNA - BJ hTERT+ [nTPM]":"10.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.0","Cell RNA - CACO-2 [nTPM]":"3.9","Cell RNA - CAPAN-2 [nTPM]":"9.5","Cell RNA - Daudi [nTPM]":"30.8","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"13.5","Cell RNA - GAMG [nTPM]":"5.8","Cell RNA - HaCaT [nTPM]":"8.9","Cell RNA - HAP1 [nTPM]":"7.2","Cell RNA - HBEC3-KT [nTPM]":"3.0","Cell RNA - HBF TERT88 [nTPM]":"8.3","Cell RNA - HDLM-2 [nTPM]":"24.3","Cell RNA - HEK 293 [nTPM]":"15.5","Cell RNA - HEL [nTPM]":"4.9","Cell RNA - HeLa [nTPM]":"40.1","Cell RNA - Hep G2 [nTPM]":"4.0","Cell RNA - HHSteC [nTPM]":"7.6","Cell RNA - HL-60 [nTPM]":"11.6","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"13.7","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.4","Cell RNA - hTERT-HME1 [nTPM]":"4.2","Cell RNA - hTERT-RPE1 [nTPM]":"19.5","Cell RNA - HUVEC TERT2 [nTPM]":"5.2","Cell RNA - JURKAT [nTPM]":"13.4","Cell RNA - K-562 [nTPM]":"1.9","Cell RNA - Karpas-707 [nTPM]":"8.9","Cell RNA - LHCN-M2 [nTPM]":"13.0","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"13.9","Cell RNA - NTERA-2 [nTPM]":"27.4","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"4.7","Cell RNA - REH [nTPM]":"17.5","Cell RNA - RH-30 [nTPM]":"9.2","Cell RNA - RPMI-8226 [nTPM]":"5.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.5","Cell RNA - RT4 [nTPM]":"4.4","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"2.3","Cell RNA - SiHa [nTPM]":"10.5","Cell RNA - SK-BR-3 [nTPM]":"6.0","Cell RNA - SK-MEL-30 [nTPM]":"4.5","Cell RNA - SuSa [nTPM]":"30.9","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"4.6","Cell RNA - TIME [nTPM]":"6.5","Cell RNA - U-138 MG [nTPM]":"2.8","Cell RNA - U-2 OS [nTPM]":"8.5","Cell RNA - U-2197 [nTPM]":"5.8","Cell RNA - U-251 MG [nTPM]":"3.9","Cell RNA - U-266\/70 [nTPM]":"7.6","Cell RNA - U-266\/84 [nTPM]":"3.1","Cell RNA - U-698 [nTPM]":"200.3","Cell RNA - U-87 MG [nTPM]":"10.2","Cell RNA - U-937 [nTPM]":"24.4","Cell RNA - WM-115 [nTPM]":"2.3","Blood RNA - basophil [nTPM]":"9.0","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"14.1","Blood RNA - gdT-cell [nTPM]":"5.9","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"4.8","Blood RNA - memory B-cell [nTPM]":"4.8","Blood RNA - memory CD4 T-cell [nTPM]":"4.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.7","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"5.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.4","Blood RNA - neutrophil [nTPM]":"5.1","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"6.8","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"45.3","Brain RNA - basal ganglia [nTPM]":"60.6","Brain RNA - cerebellum [nTPM]":"102.1","Brain RNA - cerebral cortex [nTPM]":"179.8","Brain RNA - hippocampal formation [nTPM]":"40.1","Brain RNA - hypothalamus [nTPM]":"85.4","Brain RNA - medulla oblongata [nTPM]":"192.8","Brain RNA - midbrain [nTPM]":"89.2","Brain RNA - pons [nTPM]":"163.5","Brain RNA - spinal cord [nTPM]":"93.3","Brain RNA - thalamus [nTPM]":"106.3","Brain RNA - white matter [nTPM]":"93.9","Single Cell Type RNA - Adipocytes [nTPM]":"2.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"10.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"20.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"17.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"2.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.1","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"6.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.4","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"12.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"14.8","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"VAPB","Gene synonym":["ALS8","VAP-B","VAP-C"],"Ensembl":"ENSG00000124164","Gene description":"VAMP associated protein B and C","Uniprot":["O95292"],"Chromosome":"20","Position":"58389229-58451101","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Unfolded protein response"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013144","CAB013722"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB013722":null,"HPA013144":"AB_1858717"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.08e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.7","Tissue RNA - adrenal gland [nTPM]":"36.4","Tissue RNA - amygdala [nTPM]":"32.1","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"30.4","Tissue RNA - bone marrow [nTPM]":"4.2","Tissue RNA - breast [nTPM]":"14.2","Tissue RNA - cerebellum [nTPM]":"29.6","Tissue RNA - cerebral cortex [nTPM]":"30.1","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"20.3","Tissue RNA - colon [nTPM]":"24.2","Tissue RNA - duodenum [nTPM]":"19.6","Tissue RNA - endometrium 1 [nTPM]":"16.4","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"19.3","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"9.7","Tissue RNA - heart muscle [nTPM]":"29.4","Tissue RNA - hippocampal formation [nTPM]":"28.8","Tissue RNA - hypothalamus [nTPM]":"33.5","Tissue RNA - kidney [nTPM]":"24.8","Tissue RNA - liver [nTPM]":"35.0","Tissue RNA - lung [nTPM]":"14.1","Tissue RNA - lymph node [nTPM]":"9.6","Tissue RNA - medulla oblongata [nTPM]":"34.6","Tissue RNA - midbrain [nTPM]":"34.0","Tissue RNA - ovary [nTPM]":"17.9","Tissue RNA - pancreas [nTPM]":"18.9","Tissue RNA - parathyroid gland [nTPM]":"27.9","Tissue RNA - pituitary gland [nTPM]":"21.0","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"36.2","Tissue RNA - prostate [nTPM]":"17.8","Tissue RNA - rectum [nTPM]":"9.9","Tissue RNA - retina [nTPM]":"14.3","Tissue RNA - salivary gland [nTPM]":"16.2","Tissue RNA - seminal vesicle [nTPM]":"12.3","Tissue RNA - skeletal muscle [nTPM]":"46.4","Tissue RNA - skin 1 [nTPM]":"13.0","Tissue RNA - small intestine [nTPM]":"18.2","Tissue RNA - smooth muscle [nTPM]":"11.6","Tissue RNA - spinal cord [nTPM]":"36.4","Tissue RNA - spleen [nTPM]":"15.0","Tissue RNA - stomach 1 [nTPM]":"19.0","Tissue RNA - testis [nTPM]":"8.8","Tissue RNA - thalamus [nTPM]":"37.0","Tissue RNA - thymus [nTPM]":"12.2","Tissue RNA - thyroid gland [nTPM]":"23.3","Tissue RNA - tongue [nTPM]":"39.6","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"31.5","Cell RNA - A-431 [nTPM]":"31.0","Cell RNA - A549 [nTPM]":"30.4","Cell RNA - AF22 [nTPM]":"33.6","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"30.3","Cell RNA - ASC TERT1 [nTPM]":"12.5","Cell RNA - BEWO [nTPM]":"29.5","Cell RNA - BJ [nTPM]":"27.0","Cell RNA - BJ hTERT+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"41.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.1","Cell RNA - CACO-2 [nTPM]":"123.0","Cell RNA - CAPAN-2 [nTPM]":"29.0","Cell RNA - Daudi [nTPM]":"27.2","Cell RNA - EFO-21 [nTPM]":"37.7","Cell RNA - fHDF\/TERT166 [nTPM]":"18.3","Cell RNA - GAMG [nTPM]":"32.3","Cell RNA - HaCaT [nTPM]":"57.6","Cell RNA - HAP1 [nTPM]":"27.1","Cell RNA - HBEC3-KT [nTPM]":"38.9","Cell RNA - HBF TERT88 [nTPM]":"24.6","Cell RNA - HDLM-2 [nTPM]":"12.8","Cell RNA - HEK 293 [nTPM]":"20.2","Cell RNA - HEL [nTPM]":"16.5","Cell RNA - HeLa [nTPM]":"32.2","Cell RNA - Hep G2 [nTPM]":"38.9","Cell RNA - HHSteC [nTPM]":"30.2","Cell RNA - HL-60 [nTPM]":"15.5","Cell RNA - HMC-1 [nTPM]":"19.8","Cell RNA - HSkMC [nTPM]":"28.9","Cell RNA - hTCEpi [nTPM]":"44.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.8","Cell RNA - hTERT-HME1 [nTPM]":"18.7","Cell RNA - hTERT-RPE1 [nTPM]":"19.8","Cell RNA - HUVEC TERT2 [nTPM]":"20.5","Cell RNA - JURKAT [nTPM]":"26.7","Cell RNA - K-562 [nTPM]":"39.5","Cell RNA - Karpas-707 [nTPM]":"14.9","Cell RNA - LHCN-M2 [nTPM]":"20.0","Cell RNA - MCF7 [nTPM]":"96.7","Cell RNA - MOLT-4 [nTPM]":"24.5","Cell RNA - NB-4 [nTPM]":"30.6","Cell RNA - NTERA-2 [nTPM]":"17.7","Cell RNA - OE19 [nTPM]":"60.2","Cell RNA - PC-3 [nTPM]":"40.0","Cell RNA - REH [nTPM]":"24.2","Cell RNA - RH-30 [nTPM]":"31.3","Cell RNA - RPMI-8226 [nTPM]":"18.0","Cell RNA - RPTEC TERT1 [nTPM]":"31.6","Cell RNA - RT4 [nTPM]":"40.7","Cell RNA - SCLC-21H [nTPM]":"47.1","Cell RNA - SH-SY5Y [nTPM]":"32.6","Cell RNA - SiHa [nTPM]":"44.7","Cell RNA - SK-BR-3 [nTPM]":"117.0","Cell RNA - SK-MEL-30 [nTPM]":"48.0","Cell RNA - SuSa [nTPM]":"18.4","Cell RNA - T-47d [nTPM]":"48.0","Cell RNA - THP-1 [nTPM]":"23.2","Cell RNA - TIME [nTPM]":"28.6","Cell RNA - U-138 MG [nTPM]":"65.8","Cell RNA - U-2 OS [nTPM]":"31.9","Cell RNA - U-2197 [nTPM]":"33.3","Cell RNA - U-251 MG [nTPM]":"36.9","Cell RNA - U-266\/70 [nTPM]":"19.9","Cell RNA - U-266\/84 [nTPM]":"23.1","Cell RNA - U-698 [nTPM]":"31.4","Cell RNA - U-87 MG [nTPM]":"55.7","Cell RNA - U-937 [nTPM]":"16.8","Cell RNA - WM-115 [nTPM]":"33.8","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"4.5","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"4.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"3.7","Blood RNA - NK-cell [nTPM]":"3.7","Blood RNA - non-classical monocyte [nTPM]":"3.0","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"2.7","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"32.1","Brain RNA - basal ganglia [nTPM]":"30.4","Brain RNA - cerebellum [nTPM]":"29.6","Brain RNA - cerebral cortex [nTPM]":"30.1","Brain RNA - hippocampal formation [nTPM]":"28.8","Brain RNA - hypothalamus [nTPM]":"33.5","Brain RNA - medulla oblongata [nTPM]":"34.6","Brain RNA - midbrain [nTPM]":"34.0","Brain RNA - pons [nTPM]":"36.2","Brain RNA - spinal cord [nTPM]":"36.4","Brain RNA - thalamus [nTPM]":"37.0","Brain RNA - white matter [nTPM]":"31.5","Single Cell Type RNA - Adipocytes [nTPM]":"22.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.8","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"18.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"29.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"16.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.8","Single Cell Type RNA - dendritic cells [nTPM]":"20.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"35.1","Single Cell Type RNA - Early spermatids [nTPM]":"5.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.9","Single Cell Type RNA - Endothelial cells [nTPM]":"23.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"50.3","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.0","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"23.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"40.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.1","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.4","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"10.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.1","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"17.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"22.8","Single Cell Type RNA - Muller glia cells [nTPM]":"34.3","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.5","Single Cell Type RNA - Paneth cells [nTPM]":"22.4","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"14.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"42.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.0","Single Cell Type RNA - Spermatocytes [nTPM]":"22.0","Single Cell Type RNA - Spermatogonia [nTPM]":"29.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"44.5","Single Cell Type RNA - T-cells [nTPM]":"20.5","Single Cell Type RNA - Theca cells [nTPM]":"37.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.6","Single Cell Type RNA - Urothelial cells [nTPM]":"16.6"},{"Gene":"VCAN","Gene synonym":["CSPG2","PG-M"],"Ensembl":"ENSG00000038427","Gene description":"Versican","Uniprot":["P13611"],"Chromosome":"5","Position":"83471618-83582303","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"975.7","Granulosa cells":"1131.8","Kupffer cells":"547.3","Macrophages":"605.6","monocytes":"948.1","Oligodendrocyte precursor cells":"1644.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"240.0","myeloid DC":"88.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"dendritic cells":"88.9","monocytes":"240.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"300.5","HSkMC":"199.5","hTERT-RPE1":"959.0","RPTEC TERT1":"381.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004726","CAB008979"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB008979":null,"HPA004726":"AB_1080561"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.59e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.17e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.41e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-3"},"Tissue RNA - adipose tissue [nTPM]":"42.0","Tissue RNA - adrenal gland [nTPM]":"23.9","Tissue RNA - amygdala [nTPM]":"18.6","Tissue RNA - appendix [nTPM]":"74.9","Tissue RNA - basal ganglia [nTPM]":"20.8","Tissue RNA - bone marrow [nTPM]":"32.6","Tissue RNA - breast [nTPM]":"15.6","Tissue RNA - cerebellum [nTPM]":"24.2","Tissue RNA - cerebral cortex [nTPM]":"23.0","Tissue RNA - cervix [nTPM]":"29.4","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"17.8","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"30.5","Tissue RNA - heart muscle [nTPM]":"45.0","Tissue RNA - hippocampal formation [nTPM]":"25.7","Tissue RNA - hypothalamus [nTPM]":"27.8","Tissue RNA - kidney [nTPM]":"6.5","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"34.4","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"36.1","Tissue RNA - midbrain [nTPM]":"19.3","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"73.5","Tissue RNA - pons [nTPM]":"31.3","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"11.2","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"48.0","Tissue RNA - spinal cord [nTPM]":"28.9","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"7.7","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"44.9","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"6.6","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"48.3","Tissue RNA - vagina [nTPM]":"7.2","Tissue RNA - white matter [nTPM]":"42.7","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"5.6","Cell RNA - AF22 [nTPM]":"300.5","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"119.8","Cell RNA - ASC TERT1 [nTPM]":"81.5","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"6.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.5","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"45.2","Cell RNA - fHDF\/TERT166 [nTPM]":"111.5","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"1.7","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"2.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"199.5","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"127.6","Cell RNA - hTERT-HME1 [nTPM]":"1.2","Cell RNA - hTERT-RPE1 [nTPM]":"959.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"64.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"51.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"10.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"63.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"381.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.6","Cell RNA - SH-SY5Y [nTPM]":"15.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"33.2","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"116.5","Cell RNA - U-138 MG [nTPM]":"90.6","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"168.3","Cell RNA - U-251 MG [nTPM]":"179.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"41.8","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"16.4","Blood RNA - basophil [nTPM]":"8.3","Blood RNA - classical monocyte [nTPM]":"240.0","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"31.3","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"88.9","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"3.9","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"3.5","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"94.0","Brain RNA - amygdala [nTPM]":"18.6","Brain RNA - basal ganglia [nTPM]":"20.8","Brain RNA - cerebellum [nTPM]":"24.2","Brain RNA - cerebral cortex [nTPM]":"23.0","Brain RNA - hippocampal formation [nTPM]":"25.7","Brain RNA - hypothalamus [nTPM]":"27.8","Brain RNA - medulla oblongata [nTPM]":"36.1","Brain RNA - midbrain [nTPM]":"19.3","Brain RNA - pons [nTPM]":"31.3","Brain RNA - spinal cord [nTPM]":"28.9","Brain RNA - thalamus [nTPM]":"44.9","Brain RNA - white matter [nTPM]":"42.7","Single Cell Type RNA - Adipocytes [nTPM]":"23.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.8","Single Cell Type RNA - Astrocytes [nTPM]":"128.9","Single Cell Type RNA - B-cells [nTPM]":"5.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"17.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - dendritic cells [nTPM]":"7.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"64.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"975.7","Single Cell Type RNA - Endothelial cells [nTPM]":"29.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.0","Single Cell Type RNA - Fibroblasts [nTPM]":"348.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"241.3","Single Cell Type RNA - granulocytes [nTPM]":"12.6","Single Cell Type RNA - Granulosa cells [nTPM]":"1131.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"3.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"547.3","Single Cell Type RNA - Langerhans cells [nTPM]":"83.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"605.6","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"948.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1644.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"117.8","Single Cell Type RNA - Plasma cells [nTPM]":"2.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"80.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - T-cells [nTPM]":"12.7","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"VCP","Gene synonym":["CDC48","IBMPFD","p97","TERA"],"Ensembl":"ENSG00000165280","Gene description":"Valosin containing protein","Uniprot":["P55072"],"Chromosome":"9","Position":"35053928-35072668","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","DNA damage","DNA repair","Transport","Ubl conjugation pathway"],"Molecular function":["Hydrolase"],"Disease involvement":["Amyotrophic lateral sclerosis","Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"540.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005593","HPA012728","HPA012814"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005593":"AB_2214638","HPA012728":"AB_1858730","HPA012814":"AB_1858729"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.30e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.63e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"59.8","Tissue RNA - adrenal gland [nTPM]":"88.4","Tissue RNA - amygdala [nTPM]":"56.8","Tissue RNA - appendix [nTPM]":"33.7","Tissue RNA - basal ganglia [nTPM]":"59.0","Tissue RNA - bone marrow [nTPM]":"52.0","Tissue RNA - breast [nTPM]":"54.2","Tissue RNA - cerebellum [nTPM]":"58.9","Tissue RNA - cerebral cortex [nTPM]":"58.0","Tissue RNA - cervix [nTPM]":"57.8","Tissue RNA - choroid plexus [nTPM]":"72.0","Tissue RNA - colon [nTPM]":"51.8","Tissue RNA - duodenum [nTPM]":"33.8","Tissue RNA - endometrium 1 [nTPM]":"59.0","Tissue RNA - epididymis [nTPM]":"51.6","Tissue RNA - esophagus [nTPM]":"84.9","Tissue RNA - fallopian tube [nTPM]":"49.4","Tissue RNA - gallbladder [nTPM]":"35.3","Tissue RNA - heart muscle [nTPM]":"117.5","Tissue RNA - hippocampal formation [nTPM]":"60.4","Tissue RNA - hypothalamus [nTPM]":"66.2","Tissue RNA - kidney [nTPM]":"59.1","Tissue RNA - liver [nTPM]":"87.5","Tissue RNA - lung [nTPM]":"57.2","Tissue RNA - lymph node [nTPM]":"42.5","Tissue RNA - medulla oblongata [nTPM]":"64.4","Tissue RNA - midbrain [nTPM]":"62.0","Tissue RNA - ovary [nTPM]":"46.1","Tissue RNA - pancreas [nTPM]":"61.2","Tissue RNA - parathyroid gland [nTPM]":"65.7","Tissue RNA - pituitary gland [nTPM]":"57.3","Tissue RNA - placenta [nTPM]":"46.0","Tissue RNA - pons [nTPM]":"68.2","Tissue RNA - prostate [nTPM]":"54.5","Tissue RNA - rectum [nTPM]":"36.5","Tissue RNA - retina [nTPM]":"26.3","Tissue RNA - salivary gland [nTPM]":"63.2","Tissue RNA - seminal vesicle [nTPM]":"58.9","Tissue RNA - skeletal muscle [nTPM]":"176.0","Tissue RNA - skin 1 [nTPM]":"64.0","Tissue RNA - small intestine [nTPM]":"51.8","Tissue RNA - smooth muscle [nTPM]":"42.5","Tissue RNA - spinal cord [nTPM]":"62.3","Tissue RNA - spleen [nTPM]":"64.1","Tissue RNA - stomach 1 [nTPM]":"62.5","Tissue RNA - testis [nTPM]":"45.1","Tissue RNA - thalamus [nTPM]":"63.7","Tissue RNA - thymus [nTPM]":"59.6","Tissue RNA - thyroid gland [nTPM]":"49.7","Tissue RNA - tongue [nTPM]":"135.3","Tissue RNA - tonsil [nTPM]":"53.3","Tissue RNA - urinary bladder [nTPM]":"57.9","Tissue RNA - vagina [nTPM]":"55.3","Tissue RNA - white matter [nTPM]":"69.8","Cell RNA - A-431 [nTPM]":"167.6","Cell RNA - A549 [nTPM]":"223.8","Cell RNA - AF22 [nTPM]":"124.6","Cell RNA - AN3-CA [nTPM]":"57.5","Cell RNA - ASC diff [nTPM]":"187.4","Cell RNA - ASC TERT1 [nTPM]":"135.3","Cell RNA - BEWO [nTPM]":"98.3","Cell RNA - BJ [nTPM]":"153.8","Cell RNA - BJ hTERT+ [nTPM]":"215.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"244.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"197.6","Cell RNA - CACO-2 [nTPM]":"160.0","Cell RNA - CAPAN-2 [nTPM]":"60.1","Cell RNA - Daudi [nTPM]":"140.8","Cell RNA - EFO-21 [nTPM]":"137.2","Cell RNA - fHDF\/TERT166 [nTPM]":"242.9","Cell RNA - GAMG [nTPM]":"173.1","Cell RNA - HaCaT [nTPM]":"69.5","Cell RNA - HAP1 [nTPM]":"253.1","Cell RNA - HBEC3-KT [nTPM]":"230.7","Cell RNA - HBF TERT88 [nTPM]":"227.6","Cell RNA - HDLM-2 [nTPM]":"146.2","Cell RNA - HEK 293 [nTPM]":"126.0","Cell RNA - HEL [nTPM]":"95.3","Cell RNA - HeLa [nTPM]":"216.5","Cell RNA - Hep G2 [nTPM]":"238.0","Cell RNA - HHSteC [nTPM]":"146.5","Cell RNA - HL-60 [nTPM]":"92.4","Cell RNA - HMC-1 [nTPM]":"106.2","Cell RNA - HSkMC [nTPM]":"148.5","Cell RNA - hTCEpi [nTPM]":"136.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"239.2","Cell RNA - hTERT-HME1 [nTPM]":"115.6","Cell RNA - hTERT-RPE1 [nTPM]":"104.4","Cell RNA - HUVEC TERT2 [nTPM]":"276.2","Cell RNA - JURKAT [nTPM]":"56.3","Cell RNA - K-562 [nTPM]":"97.6","Cell RNA - Karpas-707 [nTPM]":"71.4","Cell RNA - LHCN-M2 [nTPM]":"219.2","Cell RNA - MCF7 [nTPM]":"154.7","Cell RNA - MOLT-4 [nTPM]":"114.3","Cell RNA - NB-4 [nTPM]":"234.9","Cell RNA - NTERA-2 [nTPM]":"152.2","Cell RNA - OE19 [nTPM]":"82.7","Cell RNA - PC-3 [nTPM]":"219.1","Cell RNA - REH [nTPM]":"80.7","Cell RNA - RH-30 [nTPM]":"111.8","Cell RNA - RPMI-8226 [nTPM]":"72.8","Cell RNA - RPTEC TERT1 [nTPM]":"204.1","Cell RNA - RT4 [nTPM]":"175.7","Cell RNA - SCLC-21H [nTPM]":"65.7","Cell RNA - SH-SY5Y [nTPM]":"84.1","Cell RNA - SiHa [nTPM]":"100.4","Cell RNA - SK-BR-3 [nTPM]":"81.2","Cell RNA - SK-MEL-30 [nTPM]":"45.1","Cell RNA - SuSa [nTPM]":"152.2","Cell RNA - T-47d [nTPM]":"71.5","Cell RNA - THP-1 [nTPM]":"60.3","Cell RNA - TIME [nTPM]":"215.5","Cell RNA - U-138 MG [nTPM]":"77.5","Cell RNA - U-2 OS [nTPM]":"112.5","Cell RNA - U-2197 [nTPM]":"63.7","Cell RNA - U-251 MG [nTPM]":"118.6","Cell RNA - U-266\/70 [nTPM]":"41.9","Cell RNA - U-266\/84 [nTPM]":"116.5","Cell RNA - U-698 [nTPM]":"104.3","Cell RNA - U-87 MG [nTPM]":"139.5","Cell RNA - U-937 [nTPM]":"67.0","Cell RNA - WM-115 [nTPM]":"105.4","Blood RNA - basophil [nTPM]":"142.0","Blood RNA - classical monocyte [nTPM]":"62.7","Blood RNA - eosinophil [nTPM]":"75.0","Blood RNA - gdT-cell [nTPM]":"58.8","Blood RNA - intermediate monocyte [nTPM]":"70.0","Blood RNA - MAIT T-cell [nTPM]":"62.4","Blood RNA - memory B-cell [nTPM]":"59.2","Blood RNA - memory CD4 T-cell [nTPM]":"59.0","Blood RNA - memory CD8 T-cell [nTPM]":"65.6","Blood RNA - myeloid DC [nTPM]":"75.3","Blood RNA - naive B-cell [nTPM]":"53.0","Blood RNA - naive CD4 T-cell [nTPM]":"42.3","Blood RNA - naive CD8 T-cell [nTPM]":"44.4","Blood RNA - neutrophil [nTPM]":"71.1","Blood RNA - NK-cell [nTPM]":"67.1","Blood RNA - non-classical monocyte [nTPM]":"80.4","Blood RNA - plasmacytoid DC [nTPM]":"49.8","Blood RNA - T-reg [nTPM]":"91.2","Blood RNA - total PBMC [nTPM]":"111.8","Brain RNA - amygdala [nTPM]":"56.8","Brain RNA - basal ganglia [nTPM]":"59.0","Brain RNA - cerebellum [nTPM]":"58.9","Brain RNA - cerebral cortex [nTPM]":"58.0","Brain RNA - hippocampal formation [nTPM]":"60.4","Brain RNA - hypothalamus [nTPM]":"66.2","Brain RNA - medulla oblongata [nTPM]":"64.4","Brain RNA - midbrain [nTPM]":"62.0","Brain RNA - pons [nTPM]":"68.2","Brain RNA - spinal cord [nTPM]":"62.3","Brain RNA - thalamus [nTPM]":"63.7","Brain RNA - white matter [nTPM]":"69.8","Single Cell Type RNA - Adipocytes [nTPM]":"86.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"73.7","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"124.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"77.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"120.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"147.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"111.5","Single Cell Type RNA - Bipolar cells [nTPM]":"86.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"66.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"47.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"220.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"115.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"118.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"276.8","Single Cell Type RNA - dendritic cells [nTPM]":"91.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"111.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"188.6","Single Cell Type RNA - Early spermatids [nTPM]":"43.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"97.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"85.6","Single Cell Type RNA - Endothelial cells [nTPM]":"127.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"84.2","Single Cell Type RNA - Erythroid cells [nTPM]":"137.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"187.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"164.7","Single Cell Type RNA - Fibroblasts [nTPM]":"109.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"133.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"105.8","Single Cell Type RNA - granulocytes [nTPM]":"62.1","Single Cell Type RNA - Granulosa cells [nTPM]":"106.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"111.0","Single Cell Type RNA - Hepatocytes [nTPM]":"126.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"133.1","Single Cell Type RNA - Horizontal cells [nTPM]":"74.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"108.3","Single Cell Type RNA - Ionocytes [nTPM]":"89.5","Single Cell Type RNA - Kupffer cells [nTPM]":"57.9","Single Cell Type RNA - Langerhans cells [nTPM]":"65.6","Single Cell Type RNA - Late spermatids [nTPM]":"47.0","Single Cell Type RNA - Leydig cells [nTPM]":"83.9","Single Cell Type RNA - Macrophages [nTPM]":"81.5","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"159.6","Single Cell Type RNA - Muller glia cells [nTPM]":"88.7","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"247.9","Single Cell Type RNA - Paneth cells [nTPM]":"69.0","Single Cell Type RNA - Peritubular cells [nTPM]":"86.9","Single Cell Type RNA - Plasma cells [nTPM]":"267.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"118.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"77.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"113.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"102.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"90.0","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"74.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"154.9","Single Cell Type RNA - Spermatocytes [nTPM]":"144.5","Single Cell Type RNA - Spermatogonia [nTPM]":"118.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"126.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"90.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"540.6","Single Cell Type RNA - T-cells [nTPM]":"105.4","Single Cell Type RNA - Theca cells [nTPM]":"129.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"96.4","Single Cell Type RNA - Urothelial cells [nTPM]":"135.6"},{"Gene":"VEGFA","Gene synonym":["VEGF","VEGF-A","VPF"],"Ensembl":"ENSG00000112715","Gene description":"Vascular endothelial growth factor A","Uniprot":["P15692"],"Chromosome":"6","Position":"43770184-43786487","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis","Differentiation"],"Molecular function":["Developmental protein","Growth factor","Heparin-binding","Mitogen"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"349.4","Muller glia cells":"265.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"79.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-RPE1":"398.9","U-87 MG":"628.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005429","CAB039240","HPA069116","CAB069907"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":562000,"Blood concentration - Conc. blood MS [pg\/L]":"57000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB005429":"AB_2212984","CAB039240":null,"CAB069907":"AB_10001947","HPA069116":"AB_2686089"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.50e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.34e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.76e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.73e-4"},"Tissue RNA - adipose tissue [nTPM]":"155.8","Tissue RNA - adrenal gland [nTPM]":"52.7","Tissue RNA - amygdala [nTPM]":"17.6","Tissue RNA - appendix [nTPM]":"36.5","Tissue RNA - basal ganglia [nTPM]":"20.3","Tissue RNA - bone marrow [nTPM]":"45.5","Tissue RNA - breast [nTPM]":"92.4","Tissue RNA - cerebellum [nTPM]":"34.2","Tissue RNA - cerebral cortex [nTPM]":"28.2","Tissue RNA - cervix [nTPM]":"45.2","Tissue RNA - choroid plexus [nTPM]":"46.8","Tissue RNA - colon [nTPM]":"32.6","Tissue RNA - duodenum [nTPM]":"50.9","Tissue RNA - endometrium 1 [nTPM]":"104.0","Tissue RNA - epididymis [nTPM]":"10.5","Tissue RNA - esophagus [nTPM]":"61.3","Tissue RNA - fallopian tube [nTPM]":"40.9","Tissue RNA - gallbladder [nTPM]":"80.1","Tissue RNA - heart muscle [nTPM]":"208.3","Tissue RNA - hippocampal formation [nTPM]":"22.8","Tissue RNA - hypothalamus [nTPM]":"25.1","Tissue RNA - kidney [nTPM]":"116.9","Tissue RNA - liver [nTPM]":"217.3","Tissue RNA - lung [nTPM]":"94.1","Tissue RNA - lymph node [nTPM]":"9.3","Tissue RNA - medulla oblongata [nTPM]":"27.0","Tissue RNA - midbrain [nTPM]":"38.5","Tissue RNA - ovary [nTPM]":"25.0","Tissue RNA - pancreas [nTPM]":"68.1","Tissue RNA - parathyroid gland [nTPM]":"105.0","Tissue RNA - pituitary gland [nTPM]":"22.3","Tissue RNA - placenta [nTPM]":"46.2","Tissue RNA - pons [nTPM]":"26.8","Tissue RNA - prostate [nTPM]":"120.3","Tissue RNA - rectum [nTPM]":"21.4","Tissue RNA - retina [nTPM]":"229.1","Tissue RNA - salivary gland [nTPM]":"32.1","Tissue RNA - seminal vesicle [nTPM]":"17.8","Tissue RNA - skeletal muscle [nTPM]":"221.2","Tissue RNA - skin 1 [nTPM]":"44.2","Tissue RNA - small intestine [nTPM]":"44.6","Tissue RNA - smooth muscle [nTPM]":"57.1","Tissue RNA - spinal cord [nTPM]":"19.6","Tissue RNA - spleen [nTPM]":"70.1","Tissue RNA - stomach 1 [nTPM]":"63.9","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"32.0","Tissue RNA - thymus [nTPM]":"5.6","Tissue RNA - thyroid gland [nTPM]":"270.9","Tissue RNA - tongue [nTPM]":"150.9","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"122.3","Tissue RNA - vagina [nTPM]":"61.7","Tissue RNA - white matter [nTPM]":"24.9","Cell RNA - A-431 [nTPM]":"76.5","Cell RNA - A549 [nTPM]":"13.4","Cell RNA - AF22 [nTPM]":"12.5","Cell RNA - AN3-CA [nTPM]":"71.8","Cell RNA - ASC diff [nTPM]":"21.0","Cell RNA - ASC TERT1 [nTPM]":"32.9","Cell RNA - BEWO [nTPM]":"84.2","Cell RNA - BJ [nTPM]":"45.6","Cell RNA - BJ hTERT+ [nTPM]":"81.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.4","Cell RNA - CACO-2 [nTPM]":"43.1","Cell RNA - CAPAN-2 [nTPM]":"9.9","Cell RNA - Daudi [nTPM]":"24.9","Cell RNA - EFO-21 [nTPM]":"35.5","Cell RNA - fHDF\/TERT166 [nTPM]":"27.7","Cell RNA - GAMG [nTPM]":"305.4","Cell RNA - HaCaT [nTPM]":"30.6","Cell RNA - HAP1 [nTPM]":"34.0","Cell RNA - HBEC3-KT [nTPM]":"92.0","Cell RNA - HBF TERT88 [nTPM]":"52.0","Cell RNA - HDLM-2 [nTPM]":"27.4","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"19.0","Cell RNA - HeLa [nTPM]":"17.8","Cell RNA - Hep G2 [nTPM]":"29.2","Cell RNA - HHSteC [nTPM]":"220.3","Cell RNA - HL-60 [nTPM]":"20.8","Cell RNA - HMC-1 [nTPM]":"40.4","Cell RNA - HSkMC [nTPM]":"58.0","Cell RNA - hTCEpi [nTPM]":"178.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"290.6","Cell RNA - hTERT-HME1 [nTPM]":"286.2","Cell RNA - hTERT-RPE1 [nTPM]":"398.9","Cell RNA - HUVEC TERT2 [nTPM]":"7.7","Cell RNA - JURKAT [nTPM]":"21.0","Cell RNA - K-562 [nTPM]":"35.7","Cell RNA - Karpas-707 [nTPM]":"121.7","Cell RNA - LHCN-M2 [nTPM]":"109.4","Cell RNA - MCF7 [nTPM]":"31.3","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"28.3","Cell RNA - NTERA-2 [nTPM]":"7.9","Cell RNA - OE19 [nTPM]":"221.2","Cell RNA - PC-3 [nTPM]":"19.2","Cell RNA - REH [nTPM]":"2.3","Cell RNA - RH-30 [nTPM]":"12.0","Cell RNA - RPMI-8226 [nTPM]":"60.5","Cell RNA - RPTEC TERT1 [nTPM]":"114.8","Cell RNA - RT4 [nTPM]":"62.9","Cell RNA - SCLC-21H [nTPM]":"22.3","Cell RNA - SH-SY5Y [nTPM]":"46.8","Cell RNA - SiHa [nTPM]":"65.6","Cell RNA - SK-BR-3 [nTPM]":"44.4","Cell RNA - SK-MEL-30 [nTPM]":"162.0","Cell RNA - SuSa [nTPM]":"16.1","Cell RNA - T-47d [nTPM]":"17.3","Cell RNA - THP-1 [nTPM]":"75.1","Cell RNA - TIME [nTPM]":"10.4","Cell RNA - U-138 MG [nTPM]":"122.6","Cell RNA - U-2 OS [nTPM]":"32.9","Cell RNA - U-2197 [nTPM]":"179.2","Cell RNA - U-251 MG [nTPM]":"76.1","Cell RNA - U-266\/70 [nTPM]":"68.8","Cell RNA - U-266\/84 [nTPM]":"43.6","Cell RNA - U-698 [nTPM]":"49.1","Cell RNA - U-87 MG [nTPM]":"628.6","Cell RNA - U-937 [nTPM]":"47.9","Cell RNA - WM-115 [nTPM]":"43.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"17.6","Brain RNA - basal ganglia [nTPM]":"20.3","Brain RNA - cerebellum [nTPM]":"34.2","Brain RNA - cerebral cortex [nTPM]":"28.2","Brain RNA - hippocampal formation [nTPM]":"22.8","Brain RNA - hypothalamus [nTPM]":"25.1","Brain RNA - medulla oblongata [nTPM]":"27.0","Brain RNA - midbrain [nTPM]":"38.5","Brain RNA - pons [nTPM]":"26.8","Brain RNA - spinal cord [nTPM]":"19.6","Brain RNA - thalamus [nTPM]":"32.0","Brain RNA - white matter [nTPM]":"24.9","Single Cell Type RNA - Adipocytes [nTPM]":"63.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"349.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"84.7","Single Cell Type RNA - Astrocytes [nTPM]":"121.5","Single Cell Type RNA - B-cells [nTPM]":"9.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"70.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"76.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"60.3","Single Cell Type RNA - Bipolar cells [nTPM]":"37.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"67.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"57.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"164.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"77.2","Single Cell Type RNA - Club cells [nTPM]":"85.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.3","Single Cell Type RNA - dendritic cells [nTPM]":"11.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"92.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"54.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"59.1","Single Cell Type RNA - Endothelial cells [nTPM]":"29.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.4","Single Cell Type RNA - Erythroid cells [nTPM]":"21.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"40.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"69.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"124.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"121.2","Single Cell Type RNA - granulocytes [nTPM]":"112.0","Single Cell Type RNA - Granulosa cells [nTPM]":"111.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"116.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.9","Single Cell Type RNA - Horizontal cells [nTPM]":"180.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"71.8","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.2","Single Cell Type RNA - Langerhans cells [nTPM]":"199.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"144.1","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"11.3","Single Cell Type RNA - Muller glia cells [nTPM]":"265.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"124.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"86.0","Single Cell Type RNA - Paneth cells [nTPM]":"47.1","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"15.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"119.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"61.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"43.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"79.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"82.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"78.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.9","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"17.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.0","Single Cell Type RNA - Urothelial cells [nTPM]":"137.5"},{"Gene":"VIM","Gene synonym":[],"Ensembl":"ENSG00000026025","Gene description":"Vimentin","Uniprot":["P08670"],"Chromosome":"10","Position":"17228241-17237593","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"4879.0","Langerhans cells":"4893.1","Leydig cells":"5013.2","Muller glia cells":"8977.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"18287.8","fHDF\/TERT166":"10084.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000080","HPA001762","CAB058687"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"35000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"CAB000080":"AB_2304493","CAB058687":"AB_2665570","HPA001762":"AB_1080568"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.75e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.69e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Tissue RNA - adipose tissue [nTPM]":"3467.6","Tissue RNA - adrenal gland [nTPM]":"423.1","Tissue RNA - amygdala [nTPM]":"349.3","Tissue RNA - appendix [nTPM]":"610.6","Tissue RNA - basal ganglia [nTPM]":"369.5","Tissue RNA - bone marrow [nTPM]":"1455.5","Tissue RNA - breast [nTPM]":"2362.8","Tissue RNA - cerebellum [nTPM]":"289.1","Tissue RNA - cerebral cortex [nTPM]":"527.4","Tissue RNA - cervix [nTPM]":"1816.3","Tissue RNA - choroid plexus [nTPM]":"568.1","Tissue RNA - colon [nTPM]":"923.2","Tissue RNA - duodenum [nTPM]":"218.4","Tissue RNA - endometrium 1 [nTPM]":"1226.5","Tissue RNA - epididymis [nTPM]":"400.0","Tissue RNA - esophagus [nTPM]":"451.5","Tissue RNA - fallopian tube [nTPM]":"1458.7","Tissue RNA - gallbladder [nTPM]":"960.2","Tissue RNA - heart muscle [nTPM]":"1364.3","Tissue RNA - hippocampal formation [nTPM]":"337.5","Tissue RNA - hypothalamus [nTPM]":"404.6","Tissue RNA - kidney [nTPM]":"473.6","Tissue RNA - liver [nTPM]":"192.8","Tissue RNA - lung [nTPM]":"1133.2","Tissue RNA - lymph node [nTPM]":"806.2","Tissue RNA - medulla oblongata [nTPM]":"667.4","Tissue RNA - midbrain [nTPM]":"328.2","Tissue RNA - ovary [nTPM]":"3690.8","Tissue RNA - pancreas [nTPM]":"370.0","Tissue RNA - parathyroid gland [nTPM]":"224.8","Tissue RNA - pituitary gland [nTPM]":"574.5","Tissue RNA - placenta [nTPM]":"1030.0","Tissue RNA - pons [nTPM]":"443.7","Tissue RNA - prostate [nTPM]":"570.0","Tissue RNA - rectum [nTPM]":"400.8","Tissue RNA - retina [nTPM]":"731.0","Tissue RNA - salivary gland [nTPM]":"628.5","Tissue RNA - seminal vesicle [nTPM]":"551.8","Tissue RNA - skeletal muscle [nTPM]":"363.7","Tissue RNA - skin 1 [nTPM]":"1126.8","Tissue RNA - small intestine [nTPM]":"674.7","Tissue RNA - smooth muscle [nTPM]":"1109.3","Tissue RNA - spinal cord [nTPM]":"414.6","Tissue RNA - spleen [nTPM]":"819.9","Tissue RNA - stomach 1 [nTPM]":"522.8","Tissue RNA - testis [nTPM]":"251.7","Tissue RNA - thalamus [nTPM]":"472.7","Tissue RNA - thymus [nTPM]":"412.2","Tissue RNA - thyroid gland [nTPM]":"1391.1","Tissue RNA - tongue [nTPM]":"555.8","Tissue RNA - tonsil [nTPM]":"744.7","Tissue RNA - urinary bladder [nTPM]":"983.5","Tissue RNA - vagina [nTPM]":"1366.6","Tissue RNA - white matter [nTPM]":"425.5","Cell RNA - A-431 [nTPM]":"21.2","Cell RNA - A549 [nTPM]":"1119.0","Cell RNA - AF22 [nTPM]":"1981.0","Cell RNA - AN3-CA [nTPM]":"3180.7","Cell RNA - ASC diff [nTPM]":"6407.4","Cell RNA - ASC TERT1 [nTPM]":"18287.8","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"5238.5","Cell RNA - BJ hTERT+ [nTPM]":"3458.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3859.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3421.5","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"70.4","Cell RNA - Daudi [nTPM]":"2.9","Cell RNA - EFO-21 [nTPM]":"273.2","Cell RNA - fHDF\/TERT166 [nTPM]":"10084.4","Cell RNA - GAMG [nTPM]":"1804.7","Cell RNA - HaCaT [nTPM]":"8.4","Cell RNA - HAP1 [nTPM]":"283.8","Cell RNA - HBEC3-KT [nTPM]":"147.0","Cell RNA - HBF TERT88 [nTPM]":"3734.1","Cell RNA - HDLM-2 [nTPM]":"3567.5","Cell RNA - HEK 293 [nTPM]":"387.2","Cell RNA - HEL [nTPM]":"563.2","Cell RNA - HeLa [nTPM]":"523.5","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"1967.3","Cell RNA - HL-60 [nTPM]":"301.1","Cell RNA - HMC-1 [nTPM]":"222.8","Cell RNA - HSkMC [nTPM]":"6746.8","Cell RNA - hTCEpi [nTPM]":"6.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5712.0","Cell RNA - hTERT-HME1 [nTPM]":"3213.4","Cell RNA - hTERT-RPE1 [nTPM]":"9020.8","Cell RNA - HUVEC TERT2 [nTPM]":"6366.3","Cell RNA - JURKAT [nTPM]":"372.4","Cell RNA - K-562 [nTPM]":"889.3","Cell RNA - Karpas-707 [nTPM]":"1575.4","Cell RNA - LHCN-M2 [nTPM]":"6939.5","Cell RNA - MCF7 [nTPM]":"4.5","Cell RNA - MOLT-4 [nTPM]":"736.6","Cell RNA - NB-4 [nTPM]":"911.2","Cell RNA - NTERA-2 [nTPM]":"632.4","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"1394.0","Cell RNA - REH [nTPM]":"564.8","Cell RNA - RH-30 [nTPM]":"2745.9","Cell RNA - RPMI-8226 [nTPM]":"95.7","Cell RNA - RPTEC TERT1 [nTPM]":"3925.3","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"8.1","Cell RNA - SH-SY5Y [nTPM]":"946.6","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"6.9","Cell RNA - SK-MEL-30 [nTPM]":"5447.5","Cell RNA - SuSa [nTPM]":"1133.1","Cell RNA - T-47d [nTPM]":"8.6","Cell RNA - THP-1 [nTPM]":"341.8","Cell RNA - TIME [nTPM]":"5459.0","Cell RNA - U-138 MG [nTPM]":"3819.8","Cell RNA - U-2 OS [nTPM]":"1644.5","Cell RNA - U-2197 [nTPM]":"3244.7","Cell RNA - U-251 MG [nTPM]":"6311.5","Cell RNA - U-266\/70 [nTPM]":"1754.4","Cell RNA - U-266\/84 [nTPM]":"953.7","Cell RNA - U-698 [nTPM]":"130.4","Cell RNA - U-87 MG [nTPM]":"5775.4","Cell RNA - U-937 [nTPM]":"28.9","Cell RNA - WM-115 [nTPM]":"3726.3","Blood RNA - basophil [nTPM]":"667.8","Blood RNA - classical monocyte [nTPM]":"751.8","Blood RNA - eosinophil [nTPM]":"215.2","Blood RNA - gdT-cell [nTPM]":"219.5","Blood RNA - intermediate monocyte [nTPM]":"469.3","Blood RNA - MAIT T-cell [nTPM]":"278.7","Blood RNA - memory B-cell [nTPM]":"176.3","Blood RNA - memory CD4 T-cell [nTPM]":"357.0","Blood RNA - memory CD8 T-cell [nTPM]":"285.0","Blood RNA - myeloid DC [nTPM]":"866.0","Blood RNA - naive B-cell [nTPM]":"117.5","Blood RNA - naive CD4 T-cell [nTPM]":"217.1","Blood RNA - naive CD8 T-cell [nTPM]":"217.2","Blood RNA - neutrophil [nTPM]":"409.3","Blood RNA - NK-cell [nTPM]":"99.2","Blood RNA - non-classical monocyte [nTPM]":"471.2","Blood RNA - plasmacytoid DC [nTPM]":"342.3","Blood RNA - T-reg [nTPM]":"481.5","Blood RNA - total PBMC [nTPM]":"615.4","Brain RNA - amygdala [nTPM]":"349.3","Brain RNA - basal ganglia [nTPM]":"369.5","Brain RNA - cerebellum [nTPM]":"289.1","Brain RNA - cerebral cortex [nTPM]":"527.4","Brain RNA - hippocampal formation [nTPM]":"337.5","Brain RNA - hypothalamus [nTPM]":"404.6","Brain RNA - medulla oblongata [nTPM]":"667.4","Brain RNA - midbrain [nTPM]":"328.2","Brain RNA - pons [nTPM]":"443.7","Brain RNA - spinal cord [nTPM]":"414.6","Brain RNA - thalamus [nTPM]":"472.7","Brain RNA - white matter [nTPM]":"425.5","Single Cell Type RNA - Adipocytes [nTPM]":"3211.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"157.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"349.4","Single Cell Type RNA - Astrocytes [nTPM]":"53.5","Single Cell Type RNA - B-cells [nTPM]":"605.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"725.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"361.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"58.1","Single Cell Type RNA - Bipolar cells [nTPM]":"74.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"108.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"539.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"109.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"94.4","Single Cell Type RNA - Club cells [nTPM]":"157.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"108.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.1","Single Cell Type RNA - dendritic cells [nTPM]":"1110.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"198.8","Single Cell Type RNA - Early spermatids [nTPM]":"58.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"922.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2314.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2923.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"309.1","Single Cell Type RNA - Erythroid cells [nTPM]":"236.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"569.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.8","Single Cell Type RNA - Fibroblasts [nTPM]":"3443.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"101.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"693.7","Single Cell Type RNA - granulocytes [nTPM]":"2776.4","Single Cell Type RNA - Granulosa cells [nTPM]":"4879.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2195.6","Single Cell Type RNA - Hepatocytes [nTPM]":"19.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"3541.4","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2841.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4893.1","Single Cell Type RNA - Late spermatids [nTPM]":"131.6","Single Cell Type RNA - Leydig cells [nTPM]":"5013.2","Single Cell Type RNA - Macrophages [nTPM]":"3177.8","Single Cell Type RNA - Melanocytes [nTPM]":"3082.5","Single Cell Type RNA - Microglial cells [nTPM]":"85.3","Single Cell Type RNA - monocytes [nTPM]":"3893.1","Single Cell Type RNA - Muller glia cells [nTPM]":"8977.0","Single Cell Type RNA - NK-cells [nTPM]":"259.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"525.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.5","Single Cell Type RNA - Peritubular cells [nTPM]":"2336.6","Single Cell Type RNA - Plasma cells [nTPM]":"2097.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"79.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"181.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"90.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"284.1","Single Cell Type RNA - Sertoli cells [nTPM]":"1420.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3171.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3714.2","Single Cell Type RNA - Spermatocytes [nTPM]":"55.1","Single Cell Type RNA - Spermatogonia [nTPM]":"27.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"473.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.7","Single Cell Type RNA - T-cells [nTPM]":"1566.3","Single Cell Type RNA - Theca cells [nTPM]":"1791.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.2","Single Cell Type RNA - Urothelial cells [nTPM]":"28.9"},{"Gene":"VLDLR","Gene synonym":["CARMQ1","CHRMQ1","VLDLRCH"],"Ensembl":"ENSG00000147852","Gene description":"Very low density lipoprotein receptor","Uniprot":["P98155"],"Chromosome":"9","Position":"2621182-2660056","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Endocytosis","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"77.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"78.1","Cone photoreceptor cells":"104.3","Oligodendrocytes":"39.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"eosinophil":"6.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"6.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"22.3","JURKAT":"20.5","THP-1":"33.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032462","HPA051312"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytokinetic bridge","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytokinetic bridge","Centriolar satellite"],"Antibody RRID":{"CAB032462":"AB_2216805","HPA051312":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.95e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.7","Tissue RNA - adrenal gland [nTPM]":"16.3","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"6.4","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"5.3","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"10.3","Tissue RNA - choroid plexus [nTPM]":"6.4","Tissue RNA - colon [nTPM]":"6.6","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"19.2","Tissue RNA - fallopian tube [nTPM]":"13.8","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"43.7","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"10.6","Tissue RNA - liver [nTPM]":"3.1","Tissue RNA - lung [nTPM]":"10.7","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"7.7","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"77.5","Tissue RNA - pancreas [nTPM]":"27.4","Tissue RNA - parathyroid gland [nTPM]":"19.5","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"5.9","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"12.3","Tissue RNA - salivary gland [nTPM]":"11.6","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"26.2","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"6.8","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"9.0","Tissue RNA - testis [nTPM]":"6.0","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"11.6","Tissue RNA - tongue [nTPM]":"11.7","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"12.5","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"9.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"14.3","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"22.3","Cell RNA - BJ [nTPM]":"7.0","Cell RNA - BJ hTERT+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.3","Cell RNA - CACO-2 [nTPM]":"3.6","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.8","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"3.4","Cell RNA - HBEC3-KT [nTPM]":"5.6","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"9.7","Cell RNA - HEK 293 [nTPM]":"2.4","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"1.6","Cell RNA - Hep G2 [nTPM]":"1.8","Cell RNA - HHSteC [nTPM]":"1.9","Cell RNA - HL-60 [nTPM]":"9.2","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"3.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"7.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"20.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"1.1","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"9.9","Cell RNA - OE19 [nTPM]":"1.5","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.4","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"2.4","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"10.4","Cell RNA - SuSa [nTPM]":"7.5","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"33.3","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"2.8","Cell RNA - U-2 OS [nTPM]":"4.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"3.3","Cell RNA - U-266\/70 [nTPM]":"14.1","Cell RNA - U-266\/84 [nTPM]":"6.1","Cell RNA - U-698 [nTPM]":"2.6","Cell RNA - U-87 MG [nTPM]":"14.7","Cell RNA - U-937 [nTPM]":"8.2","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"6.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"6.4","Brain RNA - cerebellum [nTPM]":"5.3","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"7.7","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"5.9","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"9.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.8","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"23.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"78.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"9.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"104.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.0","Single Cell Type RNA - Fibroblasts [nTPM]":"17.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.4","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.6","Single Cell Type RNA - Paneth cells [nTPM]":"4.3","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"8.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"15.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"6.0"},{"Gene":"VPS13A","Gene synonym":["CHAC","KIAA0986"],"Ensembl":"ENSG00000197969","Gene description":"Vacuolar protein sorting 13 homolog A","Uniprot":["Q96RL7"],"Chromosome":"9","Position":"77177445-77421537","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"228.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021652","HPA021662"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021652":"AB_1858759","HPA021662":"AB_1858760"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.1","Tissue RNA - adrenal gland [nTPM]":"7.6","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"17.6","Tissue RNA - breast [nTPM]":"7.3","Tissue RNA - cerebellum [nTPM]":"11.2","Tissue RNA - cerebral cortex [nTPM]":"9.6","Tissue RNA - cervix [nTPM]":"4.4","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"9.4","Tissue RNA - duodenum [nTPM]":"16.3","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"4.7","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"9.5","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"9.9","Tissue RNA - liver [nTPM]":"7.4","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"8.8","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"8.8","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"11.4","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"8.0","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"14.6","Tissue RNA - skin 1 [nTPM]":"15.6","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"7.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"10.6","Tissue RNA - stomach 1 [nTPM]":"12.3","Tissue RNA - testis [nTPM]":"16.8","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"9.8","Tissue RNA - tonsil [nTPM]":"7.6","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"3.1","Cell RNA - A-431 [nTPM]":"21.0","Cell RNA - A549 [nTPM]":"10.4","Cell RNA - AF22 [nTPM]":"9.1","Cell RNA - AN3-CA [nTPM]":"7.9","Cell RNA - ASC diff [nTPM]":"8.5","Cell RNA - ASC TERT1 [nTPM]":"7.4","Cell RNA - BEWO [nTPM]":"13.7","Cell RNA - BJ [nTPM]":"11.4","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.1","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"9.3","Cell RNA - Daudi [nTPM]":"16.4","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"10.6","Cell RNA - GAMG [nTPM]":"11.9","Cell RNA - HaCaT [nTPM]":"27.9","Cell RNA - HAP1 [nTPM]":"13.7","Cell RNA - HBEC3-KT [nTPM]":"11.3","Cell RNA - HBF TERT88 [nTPM]":"17.4","Cell RNA - HDLM-2 [nTPM]":"15.5","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"21.7","Cell RNA - HeLa [nTPM]":"21.3","Cell RNA - Hep G2 [nTPM]":"10.3","Cell RNA - HHSteC [nTPM]":"8.3","Cell RNA - HL-60 [nTPM]":"28.3","Cell RNA - HMC-1 [nTPM]":"13.9","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"16.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.5","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"17.3","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"14.3","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"9.8","Cell RNA - MOLT-4 [nTPM]":"21.7","Cell RNA - NB-4 [nTPM]":"9.7","Cell RNA - NTERA-2 [nTPM]":"10.2","Cell RNA - OE19 [nTPM]":"11.9","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"15.7","Cell RNA - RH-30 [nTPM]":"17.4","Cell RNA - RPMI-8226 [nTPM]":"6.8","Cell RNA - RPTEC TERT1 [nTPM]":"14.1","Cell RNA - RT4 [nTPM]":"20.2","Cell RNA - SCLC-21H [nTPM]":"13.3","Cell RNA - SH-SY5Y [nTPM]":"13.3","Cell RNA - SiHa [nTPM]":"14.3","Cell RNA - SK-BR-3 [nTPM]":"9.2","Cell RNA - SK-MEL-30 [nTPM]":"6.3","Cell RNA - SuSa [nTPM]":"16.6","Cell RNA - T-47d [nTPM]":"6.3","Cell RNA - THP-1 [nTPM]":"6.3","Cell RNA - TIME [nTPM]":"18.6","Cell RNA - U-138 MG [nTPM]":"10.4","Cell RNA - U-2 OS [nTPM]":"11.3","Cell RNA - U-2197 [nTPM]":"14.4","Cell RNA - U-251 MG [nTPM]":"14.6","Cell RNA - U-266\/70 [nTPM]":"9.7","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"8.4","Cell RNA - U-87 MG [nTPM]":"10.8","Cell RNA - U-937 [nTPM]":"13.2","Cell RNA - WM-115 [nTPM]":"4.2","Blood RNA - basophil [nTPM]":"3.8","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"11.2","Brain RNA - cerebral cortex [nTPM]":"9.6","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"3.1","Single Cell Type RNA - Adipocytes [nTPM]":"29.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.5","Single Cell Type RNA - Astrocytes [nTPM]":"48.3","Single Cell Type RNA - B-cells [nTPM]":"32.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"29.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"87.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"41.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - dendritic cells [nTPM]":"42.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"78.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.2","Single Cell Type RNA - Early spermatids [nTPM]":"90.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.2","Single Cell Type RNA - Endothelial cells [nTPM]":"38.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"87.8","Single Cell Type RNA - Erythroid cells [nTPM]":"48.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"228.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.8","Single Cell Type RNA - Fibroblasts [nTPM]":"18.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"86.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.6","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"32.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"34.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.6","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"101.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"47.4","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"10.6","Single Cell Type RNA - Langerhans cells [nTPM]":"14.4","Single Cell Type RNA - Late spermatids [nTPM]":"55.0","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"13.3","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"43.1","Single Cell Type RNA - monocytes [nTPM]":"11.9","Single Cell Type RNA - Muller glia cells [nTPM]":"16.4","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"72.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"46.2","Single Cell Type RNA - Paneth cells [nTPM]":"42.9","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"42.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"98.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.5","Single Cell Type RNA - Spermatocytes [nTPM]":"74.3","Single Cell Type RNA - Spermatogonia [nTPM]":"64.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - T-cells [nTPM]":"43.2","Single Cell Type RNA - Theca cells [nTPM]":"38.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.8","Single Cell Type RNA - Urothelial cells [nTPM]":"25.7"},{"Gene":"VPS13C","Gene synonym":["FLJ10381","FLJ20136","KIAA1421"],"Ensembl":"ENSG00000129003","Gene description":"Vacuolar protein sorting 13 homolog C","Uniprot":["Q709C8"],"Chromosome":"15","Position":"61852389-62060473","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"272.2","Oligodendrocytes":"291.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043507"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA043507":"AB_10960840"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"6.0","Tissue RNA - appendix [nTPM]":"13.3","Tissue RNA - basal ganglia [nTPM]":"13.8","Tissue RNA - bone marrow [nTPM]":"10.5","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"10.2","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"11.7","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"8.9","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"12.0","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"4.1","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"9.1","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"4.4","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"8.9","Tissue RNA - liver [nTPM]":"7.2","Tissue RNA - lung [nTPM]":"10.9","Tissue RNA - lymph node [nTPM]":"17.7","Tissue RNA - medulla oblongata [nTPM]":"12.9","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"8.6","Tissue RNA - parathyroid gland [nTPM]":"12.3","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"15.2","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"9.1","Tissue RNA - retina [nTPM]":"18.8","Tissue RNA - salivary gland [nTPM]":"8.0","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"8.3","Tissue RNA - spleen [nTPM]":"17.8","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"9.9","Tissue RNA - thymus [nTPM]":"14.6","Tissue RNA - thyroid gland [nTPM]":"11.5","Tissue RNA - tongue [nTPM]":"12.8","Tissue RNA - tonsil [nTPM]":"15.1","Tissue RNA - urinary bladder [nTPM]":"9.1","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"24.6","Cell RNA - A-431 [nTPM]":"8.2","Cell RNA - A549 [nTPM]":"13.9","Cell RNA - AF22 [nTPM]":"5.2","Cell RNA - AN3-CA [nTPM]":"5.5","Cell RNA - ASC diff [nTPM]":"22.8","Cell RNA - ASC TERT1 [nTPM]":"20.1","Cell RNA - BEWO [nTPM]":"6.1","Cell RNA - BJ [nTPM]":"6.4","Cell RNA - BJ hTERT+ [nTPM]":"25.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.5","Cell RNA - CACO-2 [nTPM]":"5.8","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"27.9","Cell RNA - EFO-21 [nTPM]":"7.4","Cell RNA - fHDF\/TERT166 [nTPM]":"12.5","Cell RNA - GAMG [nTPM]":"11.6","Cell RNA - HaCaT [nTPM]":"9.3","Cell RNA - HAP1 [nTPM]":"18.8","Cell RNA - HBEC3-KT [nTPM]":"7.2","Cell RNA - HBF TERT88 [nTPM]":"5.5","Cell RNA - HDLM-2 [nTPM]":"20.1","Cell RNA - HEK 293 [nTPM]":"3.4","Cell RNA - HEL [nTPM]":"28.3","Cell RNA - HeLa [nTPM]":"7.9","Cell RNA - Hep G2 [nTPM]":"5.4","Cell RNA - HHSteC [nTPM]":"11.3","Cell RNA - HL-60 [nTPM]":"13.7","Cell RNA - HMC-1 [nTPM]":"17.6","Cell RNA - HSkMC [nTPM]":"14.3","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.7","Cell RNA - hTERT-HME1 [nTPM]":"13.9","Cell RNA - hTERT-RPE1 [nTPM]":"14.0","Cell RNA - HUVEC TERT2 [nTPM]":"19.2","Cell RNA - JURKAT [nTPM]":"28.1","Cell RNA - K-562 [nTPM]":"8.9","Cell RNA - Karpas-707 [nTPM]":"19.5","Cell RNA - LHCN-M2 [nTPM]":"9.9","Cell RNA - MCF7 [nTPM]":"3.5","Cell RNA - MOLT-4 [nTPM]":"8.1","Cell RNA - NB-4 [nTPM]":"5.4","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"8.7","Cell RNA - PC-3 [nTPM]":"3.7","Cell RNA - REH [nTPM]":"19.0","Cell RNA - RH-30 [nTPM]":"16.1","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"10.5","Cell RNA - RT4 [nTPM]":"32.5","Cell RNA - SCLC-21H [nTPM]":"7.7","Cell RNA - SH-SY5Y [nTPM]":"9.4","Cell RNA - SiHa [nTPM]":"11.5","Cell RNA - SK-BR-3 [nTPM]":"6.6","Cell RNA - SK-MEL-30 [nTPM]":"7.0","Cell RNA - SuSa [nTPM]":"9.1","Cell RNA - T-47d [nTPM]":"7.2","Cell RNA - THP-1 [nTPM]":"19.9","Cell RNA - TIME [nTPM]":"28.9","Cell RNA - U-138 MG [nTPM]":"14.0","Cell RNA - U-2 OS [nTPM]":"7.8","Cell RNA - U-2197 [nTPM]":"8.5","Cell RNA - U-251 MG [nTPM]":"8.2","Cell RNA - U-266\/70 [nTPM]":"9.8","Cell RNA - U-266\/84 [nTPM]":"9.4","Cell RNA - U-698 [nTPM]":"16.3","Cell RNA - U-87 MG [nTPM]":"11.1","Cell RNA - U-937 [nTPM]":"28.8","Cell RNA - WM-115 [nTPM]":"6.8","Blood RNA - basophil [nTPM]":"3.7","Blood RNA - classical monocyte [nTPM]":"4.2","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"5.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"5.4","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"6.0","Brain RNA - basal ganglia [nTPM]":"13.8","Brain RNA - cerebellum [nTPM]":"10.2","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"4.4","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"12.9","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"15.2","Brain RNA - spinal cord [nTPM]":"8.3","Brain RNA - thalamus [nTPM]":"9.9","Brain RNA - white matter [nTPM]":"24.6","Single Cell Type RNA - Adipocytes [nTPM]":"92.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"61.6","Single Cell Type RNA - Astrocytes [nTPM]":"161.6","Single Cell Type RNA - B-cells [nTPM]":"108.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"84.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"75.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"83.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"57.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"146.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.8","Single Cell Type RNA - dendritic cells [nTPM]":"141.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"36.7","Single Cell Type RNA - Early spermatids [nTPM]":"6.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"92.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"79.6","Single Cell Type RNA - Endothelial cells [nTPM]":"57.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"53.0","Single Cell Type RNA - Erythroid cells [nTPM]":"30.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"182.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.3","Single Cell Type RNA - Fibroblasts [nTPM]":"56.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"83.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"118.9","Single Cell Type RNA - granulocytes [nTPM]":"89.7","Single Cell Type RNA - Granulosa cells [nTPM]":"51.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.2","Single Cell Type RNA - Hepatocytes [nTPM]":"22.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.3","Single Cell Type RNA - Horizontal cells [nTPM]":"124.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"272.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.9","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"71.0","Single Cell Type RNA - Langerhans cells [nTPM]":"58.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"50.4","Single Cell Type RNA - Macrophages [nTPM]":"107.2","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"148.9","Single Cell Type RNA - monocytes [nTPM]":"118.5","Single Cell Type RNA - Muller glia cells [nTPM]":"29.6","Single Cell Type RNA - NK-cells [nTPM]":"84.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"217.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"291.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.7","Single Cell Type RNA - Paneth cells [nTPM]":"21.0","Single Cell Type RNA - Peritubular cells [nTPM]":"51.6","Single Cell Type RNA - Plasma cells [nTPM]":"83.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"113.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"84.5","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"86.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"66.9","Single Cell Type RNA - Spermatocytes [nTPM]":"20.8","Single Cell Type RNA - Spermatogonia [nTPM]":"20.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - T-cells [nTPM]":"98.8","Single Cell Type RNA - Theca cells [nTPM]":"88.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.9","Single Cell Type RNA - Urothelial cells [nTPM]":"28.3"},{"Gene":"VPS13D","Gene synonym":["FLJ10619","KIAA0453"],"Ensembl":"ENSG00000048707","Gene description":"Vacuolar protein sorting 13 homolog D","Uniprot":["Q5THJ4"],"Chromosome":"1","Position":"12230030-12512047","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"181.4","Inhibitory neurons":"149.2","Late spermatids":"208.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027332","HPA051621"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA027332":"AB_2672223","HPA051621":"AB_2681555"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.42e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"6.9","Tissue RNA - amygdala [nTPM]":"14.3","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"17.2","Tissue RNA - bone marrow [nTPM]":"5.0","Tissue RNA - breast [nTPM]":"10.3","Tissue RNA - cerebellum [nTPM]":"14.5","Tissue RNA - cerebral cortex [nTPM]":"17.9","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"18.1","Tissue RNA - colon [nTPM]":"12.2","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"12.6","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"21.9","Tissue RNA - hippocampal formation [nTPM]":"15.8","Tissue RNA - hypothalamus [nTPM]":"14.5","Tissue RNA - kidney [nTPM]":"10.5","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"8.8","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"16.5","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"10.9","Tissue RNA - parathyroid gland [nTPM]":"13.4","Tissue RNA - pituitary gland [nTPM]":"7.7","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"14.3","Tissue RNA - prostate [nTPM]":"17.4","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"14.1","Tissue RNA - salivary gland [nTPM]":"10.8","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"18.1","Tissue RNA - skin 1 [nTPM]":"24.7","Tissue RNA - small intestine [nTPM]":"8.7","Tissue RNA - smooth muscle [nTPM]":"6.0","Tissue RNA - spinal cord [nTPM]":"13.4","Tissue RNA - spleen [nTPM]":"9.3","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"17.8","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"15.3","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"10.6","Tissue RNA - white matter [nTPM]":"16.6","Cell RNA - A-431 [nTPM]":"9.3","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"5.8","Cell RNA - AN3-CA [nTPM]":"4.4","Cell RNA - ASC diff [nTPM]":"15.1","Cell RNA - ASC TERT1 [nTPM]":"11.9","Cell RNA - BEWO [nTPM]":"2.7","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"7.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.0","Cell RNA - CACO-2 [nTPM]":"3.5","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"8.7","Cell RNA - EFO-21 [nTPM]":"5.4","Cell RNA - fHDF\/TERT166 [nTPM]":"12.6","Cell RNA - GAMG [nTPM]":"6.2","Cell RNA - HaCaT [nTPM]":"8.3","Cell RNA - HAP1 [nTPM]":"10.1","Cell RNA - HBEC3-KT [nTPM]":"8.7","Cell RNA - HBF TERT88 [nTPM]":"10.3","Cell RNA - HDLM-2 [nTPM]":"4.7","Cell RNA - HEK 293 [nTPM]":"3.4","Cell RNA - HEL [nTPM]":"7.4","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"2.8","Cell RNA - HHSteC [nTPM]":"6.3","Cell RNA - HL-60 [nTPM]":"10.8","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"10.1","Cell RNA - hTCEpi [nTPM]":"11.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"9.3","Cell RNA - hTERT-RPE1 [nTPM]":"9.2","Cell RNA - HUVEC TERT2 [nTPM]":"12.0","Cell RNA - JURKAT [nTPM]":"8.2","Cell RNA - K-562 [nTPM]":"15.5","Cell RNA - Karpas-707 [nTPM]":"4.3","Cell RNA - LHCN-M2 [nTPM]":"6.9","Cell RNA - MCF7 [nTPM]":"4.3","Cell RNA - MOLT-4 [nTPM]":"6.4","Cell RNA - NB-4 [nTPM]":"4.2","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"5.0","Cell RNA - PC-3 [nTPM]":"6.5","Cell RNA - REH [nTPM]":"5.5","Cell RNA - RH-30 [nTPM]":"6.9","Cell RNA - RPMI-8226 [nTPM]":"2.6","Cell RNA - RPTEC TERT1 [nTPM]":"5.3","Cell RNA - RT4 [nTPM]":"5.4","Cell RNA - SCLC-21H [nTPM]":"2.8","Cell RNA - SH-SY5Y [nTPM]":"3.8","Cell RNA - SiHa [nTPM]":"12.9","Cell RNA - SK-BR-3 [nTPM]":"9.4","Cell RNA - SK-MEL-30 [nTPM]":"9.0","Cell RNA - SuSa [nTPM]":"5.4","Cell RNA - T-47d [nTPM]":"8.1","Cell RNA - THP-1 [nTPM]":"3.6","Cell RNA - TIME [nTPM]":"13.1","Cell RNA - U-138 MG [nTPM]":"4.6","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"12.0","Cell RNA - U-251 MG [nTPM]":"3.7","Cell RNA - U-266\/70 [nTPM]":"3.8","Cell RNA - U-266\/84 [nTPM]":"3.3","Cell RNA - U-698 [nTPM]":"13.4","Cell RNA - U-87 MG [nTPM]":"5.2","Cell RNA - U-937 [nTPM]":"7.5","Cell RNA - WM-115 [nTPM]":"7.1","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"14.3","Brain RNA - basal ganglia [nTPM]":"17.2","Brain RNA - cerebellum [nTPM]":"14.5","Brain RNA - cerebral cortex [nTPM]":"17.9","Brain RNA - hippocampal formation [nTPM]":"15.8","Brain RNA - hypothalamus [nTPM]":"14.5","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"16.5","Brain RNA - pons [nTPM]":"14.3","Brain RNA - spinal cord [nTPM]":"13.4","Brain RNA - thalamus [nTPM]":"17.8","Brain RNA - white matter [nTPM]":"16.6","Single Cell Type RNA - Adipocytes [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.4","Single Cell Type RNA - Astrocytes [nTPM]":"111.0","Single Cell Type RNA - B-cells [nTPM]":"19.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"38.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"68.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"35.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"73.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.4","Single Cell Type RNA - dendritic cells [nTPM]":"20.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.1","Single Cell Type RNA - Early spermatids [nTPM]":"83.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.5","Single Cell Type RNA - Endothelial cells [nTPM]":"23.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"181.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.2","Single Cell Type RNA - Fibroblasts [nTPM]":"19.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.1","Single Cell Type RNA - granulocytes [nTPM]":"12.6","Single Cell Type RNA - Granulosa cells [nTPM]":"26.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"21.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.5","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"149.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"17.3","Single Cell Type RNA - Langerhans cells [nTPM]":"15.5","Single Cell Type RNA - Late spermatids [nTPM]":"208.7","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"17.5","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"79.6","Single Cell Type RNA - monocytes [nTPM]":"16.7","Single Cell Type RNA - Muller glia cells [nTPM]":"23.0","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"107.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.0","Single Cell Type RNA - Paneth cells [nTPM]":"11.2","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"11.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.1","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.5","Single Cell Type RNA - Spermatocytes [nTPM]":"18.8","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.8","Single Cell Type RNA - T-cells [nTPM]":"21.4","Single Cell Type RNA - Theca cells [nTPM]":"20.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.5","Single Cell Type RNA - Urothelial cells [nTPM]":"37.3"},{"Gene":"VPS35","Gene synonym":["FLJ10752","MEM3","PARK17"],"Ensembl":"ENSG00000069329","Gene description":"VPS35 retromer complex component","Uniprot":["Q96QK1"],"Chromosome":"16","Position":"46656132-46689518","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Host-virus interaction","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040802"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endosomes","Lysosomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"500000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Endosomes","Lysosomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA040802":"AB_2677142"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.74e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Tissue RNA - adipose tissue [nTPM]":"5.4","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"9.5","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"3.2","Tissue RNA - cervix [nTPM]":"4.2","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"4.7","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"6.1","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"2.4","Tissue RNA - ovary [nTPM]":"4.7","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"6.1","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"4.5","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"3.2","Cell RNA - A549 [nTPM]":"5.0","Cell RNA - AF22 [nTPM]":"4.1","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"6.5","Cell RNA - ASC TERT1 [nTPM]":"7.3","Cell RNA - BEWO [nTPM]":"2.1","Cell RNA - BJ [nTPM]":"3.8","Cell RNA - BJ hTERT+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.7","Cell RNA - CACO-2 [nTPM]":"4.3","Cell RNA - CAPAN-2 [nTPM]":"2.7","Cell RNA - Daudi [nTPM]":"4.2","Cell RNA - EFO-21 [nTPM]":"2.3","Cell RNA - fHDF\/TERT166 [nTPM]":"6.5","Cell RNA - GAMG [nTPM]":"3.3","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"7.5","Cell RNA - HBEC3-KT [nTPM]":"7.5","Cell RNA - HBF TERT88 [nTPM]":"9.1","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"6.4","Cell RNA - HEL [nTPM]":"3.9","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"3.0","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"5.2","Cell RNA - HMC-1 [nTPM]":"5.8","Cell RNA - HSkMC [nTPM]":"5.8","Cell RNA - hTCEpi [nTPM]":"5.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.3","Cell RNA - hTERT-HME1 [nTPM]":"4.5","Cell RNA - hTERT-RPE1 [nTPM]":"6.3","Cell RNA - HUVEC TERT2 [nTPM]":"6.6","Cell RNA - JURKAT [nTPM]":"6.0","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"6.5","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"4.0","Cell RNA - NB-4 [nTPM]":"5.0","Cell RNA - NTERA-2 [nTPM]":"1.4","Cell RNA - OE19 [nTPM]":"3.0","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"5.4","Cell RNA - RH-30 [nTPM]":"5.4","Cell RNA - RPMI-8226 [nTPM]":"5.2","Cell RNA - RPTEC TERT1 [nTPM]":"5.2","Cell RNA - RT4 [nTPM]":"4.4","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"3.2","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"2.6","Cell RNA - TIME [nTPM]":"3.9","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"4.3","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"3.2","Cell RNA - U-698 [nTPM]":"4.9","Cell RNA - U-87 MG [nTPM]":"3.4","Cell RNA - U-937 [nTPM]":"4.0","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"3.2","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"2.4","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"65.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"59.4","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"84.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"72.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"80.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"98.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"72.8","Single Cell Type RNA - Bipolar cells [nTPM]":"56.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"77.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"75.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"102.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"83.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"134.5","Single Cell Type RNA - dendritic cells [nTPM]":"44.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"65.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"54.8","Single Cell Type RNA - Ductal cells [nTPM]":"111.7","Single Cell Type RNA - Early spermatids [nTPM]":"111.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"136.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"92.3","Single Cell Type RNA - Endothelial cells [nTPM]":"63.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"80.8","Single Cell Type RNA - Erythroid cells [nTPM]":"52.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"72.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"102.2","Single Cell Type RNA - Fibroblasts [nTPM]":"70.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"88.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"88.4","Single Cell Type RNA - granulocytes [nTPM]":"72.2","Single Cell Type RNA - Granulosa cells [nTPM]":"211.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"54.7","Single Cell Type RNA - Hepatocytes [nTPM]":"40.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"123.4","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"79.7","Single Cell Type RNA - Ionocytes [nTPM]":"107.8","Single Cell Type RNA - Kupffer cells [nTPM]":"108.3","Single Cell Type RNA - Langerhans cells [nTPM]":"87.9","Single Cell Type RNA - Late spermatids [nTPM]":"32.4","Single Cell Type RNA - Leydig cells [nTPM]":"77.9","Single Cell Type RNA - Macrophages [nTPM]":"113.6","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"153.0","Single Cell Type RNA - Muller glia cells [nTPM]":"71.4","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"101.1","Single Cell Type RNA - Paneth cells [nTPM]":"101.9","Single Cell Type RNA - Peritubular cells [nTPM]":"72.2","Single Cell Type RNA - Plasma cells [nTPM]":"41.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"77.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"164.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"103.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"188.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"82.6","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"57.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"88.9","Single Cell Type RNA - Spermatocytes [nTPM]":"207.9","Single Cell Type RNA - Spermatogonia [nTPM]":"118.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"101.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"87.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"113.1","Single Cell Type RNA - T-cells [nTPM]":"51.5","Single Cell Type RNA - Theca cells [nTPM]":"95.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"97.6","Single Cell Type RNA - Urothelial cells [nTPM]":"84.5"},{"Gene":"VPS37A","Gene synonym":["FLJ32642","HCRP1","PQBP2","SPG53"],"Ensembl":"ENSG00000155975","Gene description":"VPS37A subunit of ESCRT-I","Uniprot":["Q8NEZ2"],"Chromosome":"8","Position":"17246931-17302427","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024705","HPA024781"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA024705":"AB_10601776","HPA024781":"AB_10602100"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"19.4","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"14.8","Tissue RNA - basal ganglia [nTPM]":"15.1","Tissue RNA - bone marrow [nTPM]":"15.4","Tissue RNA - breast [nTPM]":"18.5","Tissue RNA - cerebellum [nTPM]":"28.7","Tissue RNA - cerebral cortex [nTPM]":"17.5","Tissue RNA - cervix [nTPM]":"21.1","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"16.8","Tissue RNA - duodenum [nTPM]":"20.9","Tissue RNA - endometrium 1 [nTPM]":"19.4","Tissue RNA - epididymis [nTPM]":"14.3","Tissue RNA - esophagus [nTPM]":"20.2","Tissue RNA - fallopian tube [nTPM]":"13.7","Tissue RNA - gallbladder [nTPM]":"16.8","Tissue RNA - heart muscle [nTPM]":"36.2","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"13.6","Tissue RNA - kidney [nTPM]":"25.0","Tissue RNA - liver [nTPM]":"27.8","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"14.2","Tissue RNA - medulla oblongata [nTPM]":"11.2","Tissue RNA - midbrain [nTPM]":"12.5","Tissue RNA - ovary [nTPM]":"18.4","Tissue RNA - pancreas [nTPM]":"17.5","Tissue RNA - parathyroid gland [nTPM]":"33.8","Tissue RNA - pituitary gland [nTPM]":"12.4","Tissue RNA - placenta [nTPM]":"29.7","Tissue RNA - pons [nTPM]":"12.1","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"55.0","Tissue RNA - salivary gland [nTPM]":"12.5","Tissue RNA - seminal vesicle [nTPM]":"23.2","Tissue RNA - skeletal muscle [nTPM]":"39.4","Tissue RNA - skin 1 [nTPM]":"14.7","Tissue RNA - small intestine [nTPM]":"17.5","Tissue RNA - smooth muscle [nTPM]":"24.4","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"12.3","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"32.3","Tissue RNA - thalamus [nTPM]":"12.2","Tissue RNA - thymus [nTPM]":"17.5","Tissue RNA - thyroid gland [nTPM]":"18.9","Tissue RNA - tongue [nTPM]":"31.2","Tissue RNA - tonsil [nTPM]":"15.2","Tissue RNA - urinary bladder [nTPM]":"25.1","Tissue RNA - vagina [nTPM]":"15.0","Tissue RNA - white matter [nTPM]":"18.4","Cell RNA - A-431 [nTPM]":"17.2","Cell RNA - A549 [nTPM]":"27.3","Cell RNA - AF22 [nTPM]":"24.0","Cell RNA - AN3-CA [nTPM]":"21.7","Cell RNA - ASC diff [nTPM]":"51.8","Cell RNA - ASC TERT1 [nTPM]":"41.5","Cell RNA - BEWO [nTPM]":"25.8","Cell RNA - BJ [nTPM]":"60.8","Cell RNA - BJ hTERT+ [nTPM]":"50.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"53.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"45.9","Cell RNA - CACO-2 [nTPM]":"17.6","Cell RNA - CAPAN-2 [nTPM]":"16.2","Cell RNA - Daudi [nTPM]":"14.6","Cell RNA - EFO-21 [nTPM]":"31.6","Cell RNA - fHDF\/TERT166 [nTPM]":"48.7","Cell RNA - GAMG [nTPM]":"50.1","Cell RNA - HaCaT [nTPM]":"16.7","Cell RNA - HAP1 [nTPM]":"27.2","Cell RNA - HBEC3-KT [nTPM]":"26.4","Cell RNA - HBF TERT88 [nTPM]":"63.8","Cell RNA - HDLM-2 [nTPM]":"15.1","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"26.5","Cell RNA - HeLa [nTPM]":"13.7","Cell RNA - Hep G2 [nTPM]":"20.2","Cell RNA - HHSteC [nTPM]":"59.7","Cell RNA - HL-60 [nTPM]":"11.3","Cell RNA - HMC-1 [nTPM]":"25.1","Cell RNA - HSkMC [nTPM]":"39.7","Cell RNA - hTCEpi [nTPM]":"50.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.4","Cell RNA - hTERT-HME1 [nTPM]":"51.5","Cell RNA - hTERT-RPE1 [nTPM]":"38.0","Cell RNA - HUVEC TERT2 [nTPM]":"38.7","Cell RNA - JURKAT [nTPM]":"22.7","Cell RNA - K-562 [nTPM]":"20.2","Cell RNA - Karpas-707 [nTPM]":"36.8","Cell RNA - LHCN-M2 [nTPM]":"57.7","Cell RNA - MCF7 [nTPM]":"11.7","Cell RNA - MOLT-4 [nTPM]":"32.0","Cell RNA - NB-4 [nTPM]":"26.9","Cell RNA - NTERA-2 [nTPM]":"23.4","Cell RNA - OE19 [nTPM]":"38.2","Cell RNA - PC-3 [nTPM]":"14.2","Cell RNA - REH [nTPM]":"15.4","Cell RNA - RH-30 [nTPM]":"26.5","Cell RNA - RPMI-8226 [nTPM]":"17.6","Cell RNA - RPTEC TERT1 [nTPM]":"45.8","Cell RNA - RT4 [nTPM]":"23.4","Cell RNA - SCLC-21H [nTPM]":"27.1","Cell RNA - SH-SY5Y [nTPM]":"14.4","Cell RNA - SiHa [nTPM]":"23.8","Cell RNA - SK-BR-3 [nTPM]":"23.9","Cell RNA - SK-MEL-30 [nTPM]":"37.9","Cell RNA - SuSa [nTPM]":"47.1","Cell RNA - T-47d [nTPM]":"15.6","Cell RNA - THP-1 [nTPM]":"22.2","Cell RNA - TIME [nTPM]":"33.4","Cell RNA - U-138 MG [nTPM]":"33.1","Cell RNA - U-2 OS [nTPM]":"16.7","Cell RNA - U-2197 [nTPM]":"47.6","Cell RNA - U-251 MG [nTPM]":"32.0","Cell RNA - U-266\/70 [nTPM]":"12.0","Cell RNA - U-266\/84 [nTPM]":"25.0","Cell RNA - U-698 [nTPM]":"17.2","Cell RNA - U-87 MG [nTPM]":"37.5","Cell RNA - U-937 [nTPM]":"19.9","Cell RNA - WM-115 [nTPM]":"33.8","Blood RNA - basophil [nTPM]":"34.0","Blood RNA - classical monocyte [nTPM]":"17.2","Blood RNA - eosinophil [nTPM]":"16.5","Blood RNA - gdT-cell [nTPM]":"13.9","Blood RNA - intermediate monocyte [nTPM]":"13.1","Blood RNA - MAIT T-cell [nTPM]":"17.1","Blood RNA - memory B-cell [nTPM]":"10.5","Blood RNA - memory CD4 T-cell [nTPM]":"13.4","Blood RNA - memory CD8 T-cell [nTPM]":"13.6","Blood RNA - myeloid DC [nTPM]":"13.4","Blood RNA - naive B-cell [nTPM]":"10.8","Blood RNA - naive CD4 T-cell [nTPM]":"12.0","Blood RNA - naive CD8 T-cell [nTPM]":"14.8","Blood RNA - neutrophil [nTPM]":"17.6","Blood RNA - NK-cell [nTPM]":"24.5","Blood RNA - non-classical monocyte [nTPM]":"12.4","Blood RNA - plasmacytoid DC [nTPM]":"11.8","Blood RNA - T-reg [nTPM]":"13.3","Blood RNA - total PBMC [nTPM]":"14.1","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"15.1","Brain RNA - cerebellum [nTPM]":"28.7","Brain RNA - cerebral cortex [nTPM]":"17.5","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"13.6","Brain RNA - medulla oblongata [nTPM]":"11.2","Brain RNA - midbrain [nTPM]":"12.5","Brain RNA - pons [nTPM]":"12.1","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"12.2","Brain RNA - white matter [nTPM]":"18.4","Single Cell Type RNA - Adipocytes [nTPM]":"31.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.6","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"21.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"26.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"40.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"25.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.1","Single Cell Type RNA - dendritic cells [nTPM]":"20.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Ductal cells [nTPM]":"29.3","Single Cell Type RNA - Early spermatids [nTPM]":"93.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"24.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"26.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"59.2","Single Cell Type RNA - Fibroblasts [nTPM]":"27.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.4","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"16.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"23.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.6","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.6","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"17.5","Single Cell Type RNA - Langerhans cells [nTPM]":"22.7","Single Cell Type RNA - Late spermatids [nTPM]":"39.6","Single Cell Type RNA - Leydig cells [nTPM]":"25.7","Single Cell Type RNA - Macrophages [nTPM]":"25.3","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"22.4","Single Cell Type RNA - Muller glia cells [nTPM]":"25.8","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.2","Single Cell Type RNA - Paneth cells [nTPM]":"13.1","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"21.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"60.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.6","Single Cell Type RNA - Spermatocytes [nTPM]":"111.6","Single Cell Type RNA - Spermatogonia [nTPM]":"43.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"37.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"113.0","Single Cell Type RNA - T-cells [nTPM]":"22.7","Single Cell Type RNA - Theca cells [nTPM]":"17.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.6","Single Cell Type RNA - Urothelial cells [nTPM]":"52.6"},{"Gene":"VSX1","Gene synonym":["PPCD","PPCD1","PPD"],"Ensembl":"ENSG00000100987","Gene description":"Visual system homeobox 1","Uniprot":["Q9NZR4"],"Chromosome":"20","Position":"25070885-25082141","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Sensory transduction","Transcription","Transcription regulation","Vision"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"14.8","retina":"35.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"23","RNA single cell type specific nTPM":{"Bipolar cells":"465.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"14.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Karpas-707":"4.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079607"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA079607":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.3","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"14.8","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"3.3","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"35.5","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"3.4","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.8","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"4.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.3","Brain RNA - cerebellum [nTPM]":"14.8","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"3.3","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"3.4","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"465.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"VWA3B","Gene synonym":["DKFZp686F2227","MGC26733"],"Ensembl":"ENSG00000168658","Gene description":"Von Willebrand factor A domain containing 3B","Uniprot":["Q502W6"],"Chromosome":"2","Position":"98087116-98313299","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"22.3","testis":"30.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"467.1","Late spermatids":"995.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hippocampal formation":"7.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036700","HPA036701"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036700":"AB_2675261","HPA036701":"AB_10673505"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"22.3","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"2.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"7.0","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"30.0","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"7.0","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"12.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"467.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"53.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"995.9","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"124.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"17.6","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"WARS1","Gene synonym":["IFI53","IFP53","WARS"],"Ensembl":"ENSG00000140105","Gene description":"Tryptophanyl-tRNA synthetase 1","Uniprot":["P23381"],"Chromosome":"14","Position":"100333790-100376805","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Angiogenesis","Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"324.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"66.4","Cytotrophoblasts":"16.5","Endothelial cells":"38.5","Hofbauer cells":"43.1","Syncytiotrophoblasts":"16.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"1345.3","non-classical monocyte":"1608.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"908.5","SK-MEL-30":"1012.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005573","HPA018944"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"49000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA005573":"AB_2667366","HPA018944":"AB_2669986"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.88e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.94e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-3"},"Tissue RNA - adipose tissue [nTPM]":"100.7","Tissue RNA - adrenal gland [nTPM]":"67.9","Tissue RNA - amygdala [nTPM]":"40.3","Tissue RNA - appendix [nTPM]":"185.6","Tissue RNA - basal ganglia [nTPM]":"44.4","Tissue RNA - bone marrow [nTPM]":"70.5","Tissue RNA - breast [nTPM]":"65.4","Tissue RNA - cerebellum [nTPM]":"40.1","Tissue RNA - cerebral cortex [nTPM]":"45.5","Tissue RNA - cervix [nTPM]":"35.9","Tissue RNA - choroid plexus [nTPM]":"45.2","Tissue RNA - colon [nTPM]":"67.8","Tissue RNA - duodenum [nTPM]":"44.8","Tissue RNA - endometrium 1 [nTPM]":"39.6","Tissue RNA - epididymis [nTPM]":"70.3","Tissue RNA - esophagus [nTPM]":"54.4","Tissue RNA - fallopian tube [nTPM]":"50.8","Tissue RNA - gallbladder [nTPM]":"48.7","Tissue RNA - heart muscle [nTPM]":"157.6","Tissue RNA - hippocampal formation [nTPM]":"44.2","Tissue RNA - hypothalamus [nTPM]":"56.0","Tissue RNA - kidney [nTPM]":"83.6","Tissue RNA - liver [nTPM]":"47.9","Tissue RNA - lung [nTPM]":"207.5","Tissue RNA - lymph node [nTPM]":"139.0","Tissue RNA - medulla oblongata [nTPM]":"72.0","Tissue RNA - midbrain [nTPM]":"52.6","Tissue RNA - ovary [nTPM]":"21.2","Tissue RNA - pancreas [nTPM]":"47.5","Tissue RNA - parathyroid gland [nTPM]":"39.2","Tissue RNA - pituitary gland [nTPM]":"63.4","Tissue RNA - placenta [nTPM]":"324.4","Tissue RNA - pons [nTPM]":"65.3","Tissue RNA - prostate [nTPM]":"49.1","Tissue RNA - rectum [nTPM]":"72.0","Tissue RNA - retina [nTPM]":"37.8","Tissue RNA - salivary gland [nTPM]":"49.5","Tissue RNA - seminal vesicle [nTPM]":"38.3","Tissue RNA - skeletal muscle [nTPM]":"74.7","Tissue RNA - skin 1 [nTPM]":"28.4","Tissue RNA - small intestine [nTPM]":"67.7","Tissue RNA - smooth muscle [nTPM]":"76.2","Tissue RNA - spinal cord [nTPM]":"47.6","Tissue RNA - spleen [nTPM]":"110.6","Tissue RNA - stomach 1 [nTPM]":"70.1","Tissue RNA - testis [nTPM]":"67.7","Tissue RNA - thalamus [nTPM]":"55.0","Tissue RNA - thymus [nTPM]":"61.7","Tissue RNA - thyroid gland [nTPM]":"159.9","Tissue RNA - tongue [nTPM]":"67.0","Tissue RNA - tonsil [nTPM]":"86.2","Tissue RNA - urinary bladder [nTPM]":"107.7","Tissue RNA - vagina [nTPM]":"30.7","Tissue RNA - white matter [nTPM]":"44.9","Cell RNA - A-431 [nTPM]":"91.2","Cell RNA - A549 [nTPM]":"85.7","Cell RNA - AF22 [nTPM]":"54.6","Cell RNA - AN3-CA [nTPM]":"319.1","Cell RNA - ASC diff [nTPM]":"78.7","Cell RNA - ASC TERT1 [nTPM]":"110.7","Cell RNA - BEWO [nTPM]":"87.3","Cell RNA - BJ [nTPM]":"117.4","Cell RNA - BJ hTERT+ [nTPM]":"220.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"232.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"301.4","Cell RNA - CACO-2 [nTPM]":"57.4","Cell RNA - CAPAN-2 [nTPM]":"80.2","Cell RNA - Daudi [nTPM]":"101.7","Cell RNA - EFO-21 [nTPM]":"105.5","Cell RNA - fHDF\/TERT166 [nTPM]":"277.4","Cell RNA - GAMG [nTPM]":"59.7","Cell RNA - HaCaT [nTPM]":"151.1","Cell RNA - HAP1 [nTPM]":"158.8","Cell RNA - HBEC3-KT [nTPM]":"130.3","Cell RNA - HBF TERT88 [nTPM]":"153.1","Cell RNA - HDLM-2 [nTPM]":"154.4","Cell RNA - HEK 293 [nTPM]":"48.3","Cell RNA - HEL [nTPM]":"64.1","Cell RNA - HeLa [nTPM]":"60.9","Cell RNA - Hep G2 [nTPM]":"72.3","Cell RNA - HHSteC [nTPM]":"908.5","Cell RNA - HL-60 [nTPM]":"184.9","Cell RNA - HMC-1 [nTPM]":"101.6","Cell RNA - HSkMC [nTPM]":"126.9","Cell RNA - hTCEpi [nTPM]":"186.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"141.3","Cell RNA - hTERT-HME1 [nTPM]":"290.1","Cell RNA - hTERT-RPE1 [nTPM]":"74.5","Cell RNA - HUVEC TERT2 [nTPM]":"225.0","Cell RNA - JURKAT [nTPM]":"66.1","Cell RNA - K-562 [nTPM]":"202.8","Cell RNA - Karpas-707 [nTPM]":"255.0","Cell RNA - LHCN-M2 [nTPM]":"107.5","Cell RNA - MCF7 [nTPM]":"178.0","Cell RNA - MOLT-4 [nTPM]":"64.3","Cell RNA - NB-4 [nTPM]":"87.1","Cell RNA - NTERA-2 [nTPM]":"55.4","Cell RNA - OE19 [nTPM]":"94.1","Cell RNA - PC-3 [nTPM]":"152.2","Cell RNA - REH [nTPM]":"51.4","Cell RNA - RH-30 [nTPM]":"86.5","Cell RNA - RPMI-8226 [nTPM]":"64.9","Cell RNA - RPTEC TERT1 [nTPM]":"119.3","Cell RNA - RT4 [nTPM]":"80.8","Cell RNA - SCLC-21H [nTPM]":"145.7","Cell RNA - SH-SY5Y [nTPM]":"84.9","Cell RNA - SiHa [nTPM]":"69.4","Cell RNA - SK-BR-3 [nTPM]":"58.7","Cell RNA - SK-MEL-30 [nTPM]":"1012.4","Cell RNA - SuSa [nTPM]":"70.5","Cell RNA - T-47d [nTPM]":"153.6","Cell RNA - THP-1 [nTPM]":"234.7","Cell RNA - TIME [nTPM]":"153.1","Cell RNA - U-138 MG [nTPM]":"25.7","Cell RNA - U-2 OS [nTPM]":"58.9","Cell RNA - U-2197 [nTPM]":"269.2","Cell RNA - U-251 MG [nTPM]":"61.3","Cell RNA - U-266\/70 [nTPM]":"446.4","Cell RNA - U-266\/84 [nTPM]":"277.1","Cell RNA - U-698 [nTPM]":"191.9","Cell RNA - U-87 MG [nTPM]":"295.0","Cell RNA - U-937 [nTPM]":"144.2","Cell RNA - WM-115 [nTPM]":"205.5","Blood RNA - basophil [nTPM]":"96.5","Blood RNA - classical monocyte [nTPM]":"471.7","Blood RNA - eosinophil [nTPM]":"610.4","Blood RNA - gdT-cell [nTPM]":"41.5","Blood RNA - intermediate monocyte [nTPM]":"1345.3","Blood RNA - MAIT T-cell [nTPM]":"38.4","Blood RNA - memory B-cell [nTPM]":"71.4","Blood RNA - memory CD4 T-cell [nTPM]":"34.5","Blood RNA - memory CD8 T-cell [nTPM]":"38.4","Blood RNA - myeloid DC [nTPM]":"337.9","Blood RNA - naive B-cell [nTPM]":"68.0","Blood RNA - naive CD4 T-cell [nTPM]":"24.8","Blood RNA - naive CD8 T-cell [nTPM]":"28.6","Blood RNA - neutrophil [nTPM]":"170.9","Blood RNA - NK-cell [nTPM]":"44.5","Blood RNA - non-classical monocyte [nTPM]":"1608.2","Blood RNA - plasmacytoid DC [nTPM]":"54.7","Blood RNA - T-reg [nTPM]":"44.8","Blood RNA - total PBMC [nTPM]":"672.7","Brain RNA - amygdala [nTPM]":"40.3","Brain RNA - basal ganglia [nTPM]":"44.4","Brain RNA - cerebellum [nTPM]":"40.1","Brain RNA - cerebral cortex [nTPM]":"45.5","Brain RNA - hippocampal formation [nTPM]":"44.2","Brain RNA - hypothalamus [nTPM]":"56.0","Brain RNA - medulla oblongata [nTPM]":"72.0","Brain RNA - midbrain [nTPM]":"52.6","Brain RNA - pons [nTPM]":"65.3","Brain RNA - spinal cord [nTPM]":"47.6","Brain RNA - thalamus [nTPM]":"55.0","Brain RNA - white matter [nTPM]":"44.9","Single Cell Type RNA - Adipocytes [nTPM]":"66.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.5","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"38.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.5","Single Cell Type RNA - Fibroblasts [nTPM]":"5.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"43.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"WASHC5","Gene synonym":["KIAA0196","SPG8"],"Ensembl":"ENSG00000164961","Gene description":"WASH complex subunit 5","Uniprot":["Q12768"],"Chromosome":"8","Position":"125024260-125091819","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"19.8","Exocrine glandular cells":"17.2","Hofbauer cells":"21.8","Proximal tubular cells":"17.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034216","CAB034219","HPA064649","HPA070916"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB034216":"AB_2234159","CAB034219":"AB_2130519","HPA064649":"AB_2685312","HPA070916":"AB_2686322"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.74e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.1","Tissue RNA - adrenal gland [nTPM]":"18.6","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"18.5","Tissue RNA - basal ganglia [nTPM]":"16.9","Tissue RNA - bone marrow [nTPM]":"21.3","Tissue RNA - breast [nTPM]":"19.6","Tissue RNA - cerebellum [nTPM]":"14.9","Tissue RNA - cerebral cortex [nTPM]":"13.2","Tissue RNA - cervix [nTPM]":"17.2","Tissue RNA - choroid plexus [nTPM]":"16.5","Tissue RNA - colon [nTPM]":"18.5","Tissue RNA - duodenum [nTPM]":"18.1","Tissue RNA - endometrium 1 [nTPM]":"16.2","Tissue RNA - epididymis [nTPM]":"15.7","Tissue RNA - esophagus [nTPM]":"16.6","Tissue RNA - fallopian tube [nTPM]":"13.3","Tissue RNA - gallbladder [nTPM]":"17.8","Tissue RNA - heart muscle [nTPM]":"16.1","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"12.5","Tissue RNA - kidney [nTPM]":"22.9","Tissue RNA - liver [nTPM]":"18.5","Tissue RNA - lung [nTPM]":"17.1","Tissue RNA - lymph node [nTPM]":"19.6","Tissue RNA - medulla oblongata [nTPM]":"14.7","Tissue RNA - midbrain [nTPM]":"13.7","Tissue RNA - ovary [nTPM]":"15.6","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"24.8","Tissue RNA - pituitary gland [nTPM]":"9.5","Tissue RNA - placenta [nTPM]":"21.2","Tissue RNA - pons [nTPM]":"14.6","Tissue RNA - prostate [nTPM]":"17.4","Tissue RNA - rectum [nTPM]":"20.1","Tissue RNA - retina [nTPM]":"11.4","Tissue RNA - salivary gland [nTPM]":"14.3","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"15.9","Tissue RNA - skin 1 [nTPM]":"13.6","Tissue RNA - small intestine [nTPM]":"14.7","Tissue RNA - smooth muscle [nTPM]":"20.2","Tissue RNA - spinal cord [nTPM]":"14.0","Tissue RNA - spleen [nTPM]":"19.3","Tissue RNA - stomach 1 [nTPM]":"16.1","Tissue RNA - testis [nTPM]":"9.5","Tissue RNA - thalamus [nTPM]":"13.8","Tissue RNA - thymus [nTPM]":"21.8","Tissue RNA - thyroid gland [nTPM]":"23.3","Tissue RNA - tongue [nTPM]":"18.5","Tissue RNA - tonsil [nTPM]":"21.0","Tissue RNA - urinary bladder [nTPM]":"21.1","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"24.7","Cell RNA - A-431 [nTPM]":"40.0","Cell RNA - A549 [nTPM]":"45.4","Cell RNA - AF22 [nTPM]":"24.9","Cell RNA - AN3-CA [nTPM]":"30.6","Cell RNA - ASC diff [nTPM]":"55.3","Cell RNA - ASC TERT1 [nTPM]":"58.8","Cell RNA - BEWO [nTPM]":"16.3","Cell RNA - BJ [nTPM]":"42.0","Cell RNA - BJ hTERT+ [nTPM]":"63.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"45.8","Cell RNA - CACO-2 [nTPM]":"17.0","Cell RNA - CAPAN-2 [nTPM]":"42.1","Cell RNA - Daudi [nTPM]":"36.1","Cell RNA - EFO-21 [nTPM]":"29.1","Cell RNA - fHDF\/TERT166 [nTPM]":"54.1","Cell RNA - GAMG [nTPM]":"25.3","Cell RNA - HaCaT [nTPM]":"30.6","Cell RNA - HAP1 [nTPM]":"40.2","Cell RNA - HBEC3-KT [nTPM]":"37.7","Cell RNA - HBF TERT88 [nTPM]":"56.8","Cell RNA - HDLM-2 [nTPM]":"47.5","Cell RNA - HEK 293 [nTPM]":"23.1","Cell RNA - HEL [nTPM]":"48.1","Cell RNA - HeLa [nTPM]":"26.5","Cell RNA - Hep G2 [nTPM]":"22.8","Cell RNA - HHSteC [nTPM]":"53.8","Cell RNA - HL-60 [nTPM]":"14.8","Cell RNA - HMC-1 [nTPM]":"46.6","Cell RNA - HSkMC [nTPM]":"58.7","Cell RNA - hTCEpi [nTPM]":"25.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.5","Cell RNA - hTERT-HME1 [nTPM]":"31.2","Cell RNA - hTERT-RPE1 [nTPM]":"33.2","Cell RNA - HUVEC TERT2 [nTPM]":"49.9","Cell RNA - JURKAT [nTPM]":"30.9","Cell RNA - K-562 [nTPM]":"28.3","Cell RNA - Karpas-707 [nTPM]":"35.6","Cell RNA - LHCN-M2 [nTPM]":"53.0","Cell RNA - MCF7 [nTPM]":"87.6","Cell RNA - MOLT-4 [nTPM]":"44.3","Cell RNA - NB-4 [nTPM]":"11.8","Cell RNA - NTERA-2 [nTPM]":"23.7","Cell RNA - OE19 [nTPM]":"66.7","Cell RNA - PC-3 [nTPM]":"46.7","Cell RNA - REH [nTPM]":"29.8","Cell RNA - RH-30 [nTPM]":"22.4","Cell RNA - RPMI-8226 [nTPM]":"36.7","Cell RNA - RPTEC TERT1 [nTPM]":"33.2","Cell RNA - RT4 [nTPM]":"48.5","Cell RNA - SCLC-21H [nTPM]":"13.1","Cell RNA - SH-SY5Y [nTPM]":"26.3","Cell RNA - SiHa [nTPM]":"48.8","Cell RNA - SK-BR-3 [nTPM]":"109.2","Cell RNA - SK-MEL-30 [nTPM]":"39.5","Cell RNA - SuSa [nTPM]":"25.8","Cell RNA - T-47d [nTPM]":"47.3","Cell RNA - THP-1 [nTPM]":"25.5","Cell RNA - TIME [nTPM]":"44.7","Cell RNA - U-138 MG [nTPM]":"23.6","Cell RNA - U-2 OS [nTPM]":"51.9","Cell RNA - U-2197 [nTPM]":"39.4","Cell RNA - U-251 MG [nTPM]":"37.7","Cell RNA - U-266\/70 [nTPM]":"31.7","Cell RNA - U-266\/84 [nTPM]":"31.2","Cell RNA - U-698 [nTPM]":"31.7","Cell RNA - U-87 MG [nTPM]":"62.4","Cell RNA - U-937 [nTPM]":"27.5","Cell RNA - WM-115 [nTPM]":"33.4","Blood RNA - basophil [nTPM]":"10.4","Blood RNA - classical monocyte [nTPM]":"17.0","Blood RNA - eosinophil [nTPM]":"12.5","Blood RNA - gdT-cell [nTPM]":"13.5","Blood RNA - intermediate monocyte [nTPM]":"20.9","Blood RNA - MAIT T-cell [nTPM]":"14.3","Blood RNA - memory B-cell [nTPM]":"9.5","Blood RNA - memory CD4 T-cell [nTPM]":"12.8","Blood RNA - memory CD8 T-cell [nTPM]":"13.9","Blood RNA - myeloid DC [nTPM]":"19.7","Blood RNA - naive B-cell [nTPM]":"10.6","Blood RNA - naive CD4 T-cell [nTPM]":"10.1","Blood RNA - naive CD8 T-cell [nTPM]":"14.3","Blood RNA - neutrophil [nTPM]":"5.8","Blood RNA - NK-cell [nTPM]":"17.2","Blood RNA - non-classical monocyte [nTPM]":"29.3","Blood RNA - plasmacytoid DC [nTPM]":"7.2","Blood RNA - T-reg [nTPM]":"16.9","Blood RNA - total PBMC [nTPM]":"13.0","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"16.9","Brain RNA - cerebellum [nTPM]":"14.9","Brain RNA - cerebral cortex [nTPM]":"13.2","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"12.5","Brain RNA - medulla oblongata [nTPM]":"14.7","Brain RNA - midbrain [nTPM]":"13.7","Brain RNA - pons [nTPM]":"14.6","Brain RNA - spinal cord [nTPM]":"14.0","Brain RNA - thalamus [nTPM]":"13.8","Brain RNA - white matter [nTPM]":"24.7","Single Cell Type RNA - Adipocytes [nTPM]":"10.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.4","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.8","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"11.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"8.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.3","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"9.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"WBP2","Gene synonym":["GRAMD6","WBP-2"],"Ensembl":"ENSG00000132471","Gene description":"WW domain binding protein 2","Uniprot":["Q969T9"],"Chromosome":"17","Position":"75845699-75856507","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"321.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065682","HPA068819"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"440000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA065682":"AB_2685530","HPA068819":"AB_2686042"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Tissue RNA - adipose tissue [nTPM]":"113.2","Tissue RNA - adrenal gland [nTPM]":"223.6","Tissue RNA - amygdala [nTPM]":"239.5","Tissue RNA - appendix [nTPM]":"57.1","Tissue RNA - basal ganglia [nTPM]":"238.6","Tissue RNA - bone marrow [nTPM]":"82.7","Tissue RNA - breast [nTPM]":"114.1","Tissue RNA - cerebellum [nTPM]":"225.1","Tissue RNA - cerebral cortex [nTPM]":"340.9","Tissue RNA - cervix [nTPM]":"103.2","Tissue RNA - choroid plexus [nTPM]":"163.6","Tissue RNA - colon [nTPM]":"109.7","Tissue RNA - duodenum [nTPM]":"65.2","Tissue RNA - endometrium 1 [nTPM]":"84.6","Tissue RNA - epididymis [nTPM]":"44.3","Tissue RNA - esophagus [nTPM]":"94.7","Tissue RNA - fallopian tube [nTPM]":"106.1","Tissue RNA - gallbladder [nTPM]":"62.8","Tissue RNA - heart muscle [nTPM]":"183.1","Tissue RNA - hippocampal formation [nTPM]":"243.0","Tissue RNA - hypothalamus [nTPM]":"242.2","Tissue RNA - kidney [nTPM]":"125.7","Tissue RNA - liver [nTPM]":"184.4","Tissue RNA - lung [nTPM]":"118.1","Tissue RNA - lymph node [nTPM]":"60.9","Tissue RNA - medulla oblongata [nTPM]":"293.9","Tissue RNA - midbrain [nTPM]":"256.8","Tissue RNA - ovary [nTPM]":"113.9","Tissue RNA - pancreas [nTPM]":"134.5","Tissue RNA - parathyroid gland [nTPM]":"100.7","Tissue RNA - pituitary gland [nTPM]":"116.0","Tissue RNA - placenta [nTPM]":"55.4","Tissue RNA - pons [nTPM]":"286.4","Tissue RNA - prostate [nTPM]":"103.5","Tissue RNA - rectum [nTPM]":"39.0","Tissue RNA - retina [nTPM]":"129.7","Tissue RNA - salivary gland [nTPM]":"137.7","Tissue RNA - seminal vesicle [nTPM]":"73.5","Tissue RNA - skeletal muscle [nTPM]":"250.2","Tissue RNA - skin 1 [nTPM]":"131.3","Tissue RNA - small intestine [nTPM]":"85.7","Tissue RNA - smooth muscle [nTPM]":"52.0","Tissue RNA - spinal cord [nTPM]":"226.4","Tissue RNA - spleen [nTPM]":"112.5","Tissue RNA - stomach 1 [nTPM]":"123.2","Tissue RNA - testis [nTPM]":"95.4","Tissue RNA - thalamus [nTPM]":"259.8","Tissue RNA - thymus [nTPM]":"49.2","Tissue RNA - thyroid gland [nTPM]":"83.8","Tissue RNA - tongue [nTPM]":"91.9","Tissue RNA - tonsil [nTPM]":"51.8","Tissue RNA - urinary bladder [nTPM]":"97.8","Tissue RNA - vagina [nTPM]":"94.7","Tissue RNA - white matter [nTPM]":"256.6","Cell RNA - A-431 [nTPM]":"104.6","Cell RNA - A549 [nTPM]":"119.9","Cell RNA - AF22 [nTPM]":"43.4","Cell RNA - AN3-CA [nTPM]":"52.5","Cell RNA - ASC diff [nTPM]":"88.0","Cell RNA - ASC TERT1 [nTPM]":"87.2","Cell RNA - BEWO [nTPM]":"57.9","Cell RNA - BJ [nTPM]":"32.7","Cell RNA - BJ hTERT+ [nTPM]":"102.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"74.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.8","Cell RNA - CACO-2 [nTPM]":"59.7","Cell RNA - CAPAN-2 [nTPM]":"104.2","Cell RNA - Daudi [nTPM]":"52.9","Cell RNA - EFO-21 [nTPM]":"81.9","Cell RNA - fHDF\/TERT166 [nTPM]":"47.0","Cell RNA - GAMG [nTPM]":"232.2","Cell RNA - HaCaT [nTPM]":"61.0","Cell RNA - HAP1 [nTPM]":"45.2","Cell RNA - HBEC3-KT [nTPM]":"100.9","Cell RNA - HBF TERT88 [nTPM]":"66.3","Cell RNA - HDLM-2 [nTPM]":"40.1","Cell RNA - HEK 293 [nTPM]":"90.4","Cell RNA - HEL [nTPM]":"97.7","Cell RNA - HeLa [nTPM]":"66.4","Cell RNA - Hep G2 [nTPM]":"97.6","Cell RNA - HHSteC [nTPM]":"182.2","Cell RNA - HL-60 [nTPM]":"40.8","Cell RNA - HMC-1 [nTPM]":"161.6","Cell RNA - HSkMC [nTPM]":"96.4","Cell RNA - hTCEpi [nTPM]":"94.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"89.4","Cell RNA - hTERT-HME1 [nTPM]":"120.8","Cell RNA - hTERT-RPE1 [nTPM]":"127.0","Cell RNA - HUVEC TERT2 [nTPM]":"143.8","Cell RNA - JURKAT [nTPM]":"82.1","Cell RNA - K-562 [nTPM]":"68.2","Cell RNA - Karpas-707 [nTPM]":"156.7","Cell RNA - LHCN-M2 [nTPM]":"60.2","Cell RNA - MCF7 [nTPM]":"107.3","Cell RNA - MOLT-4 [nTPM]":"85.8","Cell RNA - NB-4 [nTPM]":"85.8","Cell RNA - NTERA-2 [nTPM]":"37.3","Cell RNA - OE19 [nTPM]":"70.8","Cell RNA - PC-3 [nTPM]":"78.8","Cell RNA - REH [nTPM]":"57.8","Cell RNA - RH-30 [nTPM]":"85.4","Cell RNA - RPMI-8226 [nTPM]":"101.5","Cell RNA - RPTEC TERT1 [nTPM]":"109.7","Cell RNA - RT4 [nTPM]":"62.3","Cell RNA - SCLC-21H [nTPM]":"72.6","Cell RNA - SH-SY5Y [nTPM]":"114.8","Cell RNA - SiHa [nTPM]":"58.5","Cell RNA - SK-BR-3 [nTPM]":"99.9","Cell RNA - SK-MEL-30 [nTPM]":"163.1","Cell RNA - SuSa [nTPM]":"76.3","Cell RNA - T-47d [nTPM]":"134.9","Cell RNA - THP-1 [nTPM]":"102.1","Cell RNA - TIME [nTPM]":"84.3","Cell RNA - U-138 MG [nTPM]":"75.8","Cell RNA - U-2 OS [nTPM]":"66.1","Cell RNA - U-2197 [nTPM]":"73.6","Cell RNA - U-251 MG [nTPM]":"52.3","Cell RNA - U-266\/70 [nTPM]":"145.4","Cell RNA - U-266\/84 [nTPM]":"109.6","Cell RNA - U-698 [nTPM]":"38.8","Cell RNA - U-87 MG [nTPM]":"212.5","Cell RNA - U-937 [nTPM]":"38.3","Cell RNA - WM-115 [nTPM]":"54.9","Blood RNA - basophil [nTPM]":"239.9","Blood RNA - classical monocyte [nTPM]":"85.0","Blood RNA - eosinophil [nTPM]":"288.7","Blood RNA - gdT-cell [nTPM]":"53.8","Blood RNA - intermediate monocyte [nTPM]":"102.6","Blood RNA - MAIT T-cell [nTPM]":"59.1","Blood RNA - memory B-cell [nTPM]":"68.9","Blood RNA - memory CD4 T-cell [nTPM]":"59.5","Blood RNA - memory CD8 T-cell [nTPM]":"54.6","Blood RNA - myeloid DC [nTPM]":"54.8","Blood RNA - naive B-cell [nTPM]":"55.3","Blood RNA - naive CD4 T-cell [nTPM]":"55.8","Blood RNA - naive CD8 T-cell [nTPM]":"47.5","Blood RNA - neutrophil [nTPM]":"308.9","Blood RNA - NK-cell [nTPM]":"57.4","Blood RNA - non-classical monocyte [nTPM]":"136.4","Blood RNA - plasmacytoid DC [nTPM]":"42.0","Blood RNA - T-reg [nTPM]":"77.4","Blood RNA - total PBMC [nTPM]":"93.2","Brain RNA - amygdala [nTPM]":"239.5","Brain RNA - basal ganglia [nTPM]":"238.6","Brain RNA - cerebellum [nTPM]":"225.1","Brain RNA - cerebral cortex [nTPM]":"340.9","Brain RNA - hippocampal formation [nTPM]":"243.0","Brain RNA - hypothalamus [nTPM]":"242.2","Brain RNA - medulla oblongata [nTPM]":"293.9","Brain RNA - midbrain [nTPM]":"256.8","Brain RNA - pons [nTPM]":"286.4","Brain RNA - spinal cord [nTPM]":"226.4","Brain RNA - thalamus [nTPM]":"259.8","Brain RNA - white matter [nTPM]":"256.6","Single Cell Type RNA - Adipocytes [nTPM]":"73.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"79.0","Single Cell Type RNA - Astrocytes [nTPM]":"34.9","Single Cell Type RNA - B-cells [nTPM]":"62.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"60.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"127.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"85.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"109.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"75.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"53.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"73.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"55.8","Single Cell Type RNA - Club cells [nTPM]":"59.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"75.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.9","Single Cell Type RNA - dendritic cells [nTPM]":"45.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"65.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"162.4","Single Cell Type RNA - Ductal cells [nTPM]":"124.3","Single Cell Type RNA - Early spermatids [nTPM]":"264.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.7","Single Cell Type RNA - Endothelial cells [nTPM]":"63.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.6","Single Cell Type RNA - Erythroid cells [nTPM]":"124.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"188.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"65.1","Single Cell Type RNA - Fibroblasts [nTPM]":"43.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.3","Single Cell Type RNA - granulocytes [nTPM]":"67.0","Single Cell Type RNA - Granulosa cells [nTPM]":"40.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"54.3","Single Cell Type RNA - Hepatocytes [nTPM]":"61.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"138.4","Single Cell Type RNA - Horizontal cells [nTPM]":"112.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"48.9","Single Cell Type RNA - Ionocytes [nTPM]":"71.2","Single Cell Type RNA - Kupffer cells [nTPM]":"65.5","Single Cell Type RNA - Langerhans cells [nTPM]":"71.2","Single Cell Type RNA - Late spermatids [nTPM]":"321.1","Single Cell Type RNA - Leydig cells [nTPM]":"59.4","Single Cell Type RNA - Macrophages [nTPM]":"90.2","Single Cell Type RNA - Melanocytes [nTPM]":"60.5","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"90.8","Single Cell Type RNA - Muller glia cells [nTPM]":"104.8","Single Cell Type RNA - NK-cells [nTPM]":"52.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"38.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"126.5","Single Cell Type RNA - Paneth cells [nTPM]":"72.6","Single Cell Type RNA - Peritubular cells [nTPM]":"53.8","Single Cell Type RNA - Plasma cells [nTPM]":"35.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"120.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"88.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"100.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"44.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"120.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.9","Single Cell Type RNA - Spermatocytes [nTPM]":"45.5","Single Cell Type RNA - Spermatogonia [nTPM]":"25.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"80.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"184.7","Single Cell Type RNA - T-cells [nTPM]":"51.7","Single Cell Type RNA - Theca cells [nTPM]":"62.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.1","Single Cell Type RNA - Urothelial cells [nTPM]":"95.6"},{"Gene":"WDR36","Gene synonym":["GLC1G","TA-WDRP","UTP21"],"Ensembl":"ENSG00000134987","Gene description":"WD repeat domain 36","Uniprot":["Q8NI36"],"Chromosome":"5","Position":"111091716-111130502","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis","rRNA processing","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Glaucoma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"113.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037796","HPA037797"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA037796":"AB_2675673","HPA037797":"AB_10672725"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"9.4","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"9.9","Tissue RNA - breast [nTPM]":"10.1","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"7.4","Tissue RNA - choroid plexus [nTPM]":"4.1","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"6.6","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"6.8","Tissue RNA - gallbladder [nTPM]":"7.2","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"11.3","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"4.0","Tissue RNA - ovary [nTPM]":"10.1","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"7.3","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"7.5","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"9.1","Tissue RNA - skin 1 [nTPM]":"10.1","Tissue RNA - small intestine [nTPM]":"6.8","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"3.8","Tissue RNA - spleen [nTPM]":"8.8","Tissue RNA - stomach 1 [nTPM]":"7.3","Tissue RNA - testis [nTPM]":"6.3","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"9.1","Tissue RNA - thyroid gland [nTPM]":"9.7","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"17.0","Cell RNA - A549 [nTPM]":"14.9","Cell RNA - AF22 [nTPM]":"13.7","Cell RNA - AN3-CA [nTPM]":"36.6","Cell RNA - ASC diff [nTPM]":"24.7","Cell RNA - ASC TERT1 [nTPM]":"32.2","Cell RNA - BEWO [nTPM]":"19.2","Cell RNA - BJ [nTPM]":"14.6","Cell RNA - BJ hTERT+ [nTPM]":"13.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.9","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"19.7","Cell RNA - Daudi [nTPM]":"53.8","Cell RNA - EFO-21 [nTPM]":"17.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.2","Cell RNA - GAMG [nTPM]":"22.7","Cell RNA - HaCaT [nTPM]":"19.2","Cell RNA - HAP1 [nTPM]":"26.8","Cell RNA - HBEC3-KT [nTPM]":"33.8","Cell RNA - HBF TERT88 [nTPM]":"34.8","Cell RNA - HDLM-2 [nTPM]":"15.9","Cell RNA - HEK 293 [nTPM]":"15.7","Cell RNA - HEL [nTPM]":"26.6","Cell RNA - HeLa [nTPM]":"17.2","Cell RNA - Hep G2 [nTPM]":"19.5","Cell RNA - HHSteC [nTPM]":"26.3","Cell RNA - HL-60 [nTPM]":"25.6","Cell RNA - HMC-1 [nTPM]":"38.8","Cell RNA - HSkMC [nTPM]":"19.2","Cell RNA - hTCEpi [nTPM]":"21.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.6","Cell RNA - hTERT-HME1 [nTPM]":"37.5","Cell RNA - hTERT-RPE1 [nTPM]":"36.5","Cell RNA - HUVEC TERT2 [nTPM]":"20.3","Cell RNA - JURKAT [nTPM]":"18.4","Cell RNA - K-562 [nTPM]":"32.3","Cell RNA - Karpas-707 [nTPM]":"18.1","Cell RNA - LHCN-M2 [nTPM]":"25.8","Cell RNA - MCF7 [nTPM]":"14.3","Cell RNA - MOLT-4 [nTPM]":"31.7","Cell RNA - NB-4 [nTPM]":"24.9","Cell RNA - NTERA-2 [nTPM]":"18.3","Cell RNA - OE19 [nTPM]":"16.8","Cell RNA - PC-3 [nTPM]":"15.6","Cell RNA - REH [nTPM]":"25.6","Cell RNA - RH-30 [nTPM]":"29.9","Cell RNA - RPMI-8226 [nTPM]":"42.4","Cell RNA - RPTEC TERT1 [nTPM]":"18.1","Cell RNA - RT4 [nTPM]":"19.3","Cell RNA - SCLC-21H [nTPM]":"24.3","Cell RNA - SH-SY5Y [nTPM]":"19.5","Cell RNA - SiHa [nTPM]":"18.6","Cell RNA - SK-BR-3 [nTPM]":"15.2","Cell RNA - SK-MEL-30 [nTPM]":"22.4","Cell RNA - SuSa [nTPM]":"15.0","Cell RNA - T-47d [nTPM]":"15.2","Cell RNA - THP-1 [nTPM]":"21.3","Cell RNA - TIME [nTPM]":"19.1","Cell RNA - U-138 MG [nTPM]":"28.1","Cell RNA - U-2 OS [nTPM]":"15.6","Cell RNA - U-2197 [nTPM]":"20.0","Cell RNA - U-251 MG [nTPM]":"30.5","Cell RNA - U-266\/70 [nTPM]":"18.1","Cell RNA - U-266\/84 [nTPM]":"14.0","Cell RNA - U-698 [nTPM]":"48.6","Cell RNA - U-87 MG [nTPM]":"22.4","Cell RNA - U-937 [nTPM]":"37.9","Cell RNA - WM-115 [nTPM]":"22.2","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.7","Blood RNA - myeloid DC [nTPM]":"4.0","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.3","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"5.0","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"3.8","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"4.0","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.8","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"17.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.8","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"61.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"113.3","Single Cell Type RNA - Bipolar cells [nTPM]":"9.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"19.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - dendritic cells [nTPM]":"15.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.5","Single Cell Type RNA - Early spermatids [nTPM]":"5.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.0","Single Cell Type RNA - Endothelial cells [nTPM]":"20.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"20.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.9","Single Cell Type RNA - Fibroblasts [nTPM]":"20.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.2","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"16.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"35.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.7","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"24.1","Single Cell Type RNA - Langerhans cells [nTPM]":"16.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"18.2","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"18.3","Single Cell Type RNA - Muller glia cells [nTPM]":"5.7","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.9","Single Cell Type RNA - Paneth cells [nTPM]":"6.4","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"27.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"18.5","Single Cell Type RNA - Spermatogonia [nTPM]":"17.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"42.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"57.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - T-cells [nTPM]":"18.0","Single Cell Type RNA - Theca cells [nTPM]":"18.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.4","Single Cell Type RNA - Urothelial cells [nTPM]":"11.2"},{"Gene":"WDR45","Gene synonym":["JM5","NBIA5","WDRX1","WIPI4"],"Ensembl":"ENSG00000196998","Gene description":"WD repeat domain 45","Uniprot":["Q9Y484"],"Chromosome":"X","Position":"49074433-49101170","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027562"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027562":"AB_10610565"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"58.0","Tissue RNA - adrenal gland [nTPM]":"74.7","Tissue RNA - amygdala [nTPM]":"53.3","Tissue RNA - appendix [nTPM]":"22.4","Tissue RNA - basal ganglia [nTPM]":"59.1","Tissue RNA - bone marrow [nTPM]":"43.2","Tissue RNA - breast [nTPM]":"54.3","Tissue RNA - cerebellum [nTPM]":"56.1","Tissue RNA - cerebral cortex [nTPM]":"57.8","Tissue RNA - cervix [nTPM]":"54.8","Tissue RNA - choroid plexus [nTPM]":"59.4","Tissue RNA - colon [nTPM]":"52.3","Tissue RNA - duodenum [nTPM]":"27.6","Tissue RNA - endometrium 1 [nTPM]":"51.5","Tissue RNA - epididymis [nTPM]":"208.4","Tissue RNA - esophagus [nTPM]":"38.5","Tissue RNA - fallopian tube [nTPM]":"45.7","Tissue RNA - gallbladder [nTPM]":"29.7","Tissue RNA - heart muscle [nTPM]":"79.6","Tissue RNA - hippocampal formation [nTPM]":"53.6","Tissue RNA - hypothalamus [nTPM]":"55.3","Tissue RNA - kidney [nTPM]":"61.8","Tissue RNA - liver [nTPM]":"68.5","Tissue RNA - lung [nTPM]":"46.6","Tissue RNA - lymph node [nTPM]":"25.7","Tissue RNA - medulla oblongata [nTPM]":"63.8","Tissue RNA - midbrain [nTPM]":"61.1","Tissue RNA - ovary [nTPM]":"49.0","Tissue RNA - pancreas [nTPM]":"58.6","Tissue RNA - parathyroid gland [nTPM]":"54.8","Tissue RNA - pituitary gland [nTPM]":"43.4","Tissue RNA - placenta [nTPM]":"21.9","Tissue RNA - pons [nTPM]":"58.1","Tissue RNA - prostate [nTPM]":"48.9","Tissue RNA - rectum [nTPM]":"19.6","Tissue RNA - retina [nTPM]":"21.2","Tissue RNA - salivary gland [nTPM]":"50.8","Tissue RNA - seminal vesicle [nTPM]":"34.4","Tissue RNA - skeletal muscle [nTPM]":"115.9","Tissue RNA - skin 1 [nTPM]":"48.5","Tissue RNA - small intestine [nTPM]":"38.2","Tissue RNA - smooth muscle [nTPM]":"24.7","Tissue RNA - spinal cord [nTPM]":"57.8","Tissue RNA - spleen [nTPM]":"45.0","Tissue RNA - stomach 1 [nTPM]":"59.0","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"61.0","Tissue RNA - thymus [nTPM]":"32.3","Tissue RNA - thyroid gland [nTPM]":"52.9","Tissue RNA - tongue [nTPM]":"87.5","Tissue RNA - tonsil [nTPM]":"23.2","Tissue RNA - urinary bladder [nTPM]":"45.9","Tissue RNA - vagina [nTPM]":"43.0","Tissue RNA - white matter [nTPM]":"52.7","Cell RNA - A-431 [nTPM]":"36.3","Cell RNA - A549 [nTPM]":"41.9","Cell RNA - AF22 [nTPM]":"23.4","Cell RNA - AN3-CA [nTPM]":"23.7","Cell RNA - ASC diff [nTPM]":"50.1","Cell RNA - ASC TERT1 [nTPM]":"63.7","Cell RNA - BEWO [nTPM]":"45.7","Cell RNA - BJ [nTPM]":"39.0","Cell RNA - BJ hTERT+ [nTPM]":"80.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.1","Cell RNA - CACO-2 [nTPM]":"22.1","Cell RNA - CAPAN-2 [nTPM]":"51.5","Cell RNA - Daudi [nTPM]":"25.1","Cell RNA - EFO-21 [nTPM]":"21.6","Cell RNA - fHDF\/TERT166 [nTPM]":"77.1","Cell RNA - GAMG [nTPM]":"38.6","Cell RNA - HaCaT [nTPM]":"30.8","Cell RNA - HAP1 [nTPM]":"35.3","Cell RNA - HBEC3-KT [nTPM]":"31.6","Cell RNA - HBF TERT88 [nTPM]":"21.6","Cell RNA - HDLM-2 [nTPM]":"27.6","Cell RNA - HEK 293 [nTPM]":"61.0","Cell RNA - HEL [nTPM]":"15.6","Cell RNA - HeLa [nTPM]":"79.5","Cell RNA - Hep G2 [nTPM]":"33.5","Cell RNA - HHSteC [nTPM]":"114.2","Cell RNA - HL-60 [nTPM]":"12.1","Cell RNA - HMC-1 [nTPM]":"34.5","Cell RNA - HSkMC [nTPM]":"57.2","Cell RNA - hTCEpi [nTPM]":"54.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.4","Cell RNA - hTERT-HME1 [nTPM]":"52.1","Cell RNA - hTERT-RPE1 [nTPM]":"47.8","Cell RNA - HUVEC TERT2 [nTPM]":"30.7","Cell RNA - JURKAT [nTPM]":"23.8","Cell RNA - K-562 [nTPM]":"33.3","Cell RNA - Karpas-707 [nTPM]":"42.8","Cell RNA - LHCN-M2 [nTPM]":"40.3","Cell RNA - MCF7 [nTPM]":"40.9","Cell RNA - MOLT-4 [nTPM]":"25.6","Cell RNA - NB-4 [nTPM]":"31.0","Cell RNA - NTERA-2 [nTPM]":"23.8","Cell RNA - OE19 [nTPM]":"15.9","Cell RNA - PC-3 [nTPM]":"36.3","Cell RNA - REH [nTPM]":"20.4","Cell RNA - RH-30 [nTPM]":"34.8","Cell RNA - RPMI-8226 [nTPM]":"85.7","Cell RNA - RPTEC TERT1 [nTPM]":"53.2","Cell RNA - RT4 [nTPM]":"32.8","Cell RNA - SCLC-21H [nTPM]":"31.3","Cell RNA - SH-SY5Y [nTPM]":"46.8","Cell RNA - SiHa [nTPM]":"49.2","Cell RNA - SK-BR-3 [nTPM]":"37.5","Cell RNA - SK-MEL-30 [nTPM]":"120.5","Cell RNA - SuSa [nTPM]":"29.9","Cell RNA - T-47d [nTPM]":"23.9","Cell RNA - THP-1 [nTPM]":"43.4","Cell RNA - TIME [nTPM]":"41.8","Cell RNA - U-138 MG [nTPM]":"32.8","Cell RNA - U-2 OS [nTPM]":"29.4","Cell RNA - U-2197 [nTPM]":"65.6","Cell RNA - U-251 MG [nTPM]":"16.6","Cell RNA - U-266\/70 [nTPM]":"66.2","Cell RNA - U-266\/84 [nTPM]":"48.9","Cell RNA - U-698 [nTPM]":"18.1","Cell RNA - U-87 MG [nTPM]":"60.1","Cell RNA - U-937 [nTPM]":"19.5","Cell RNA - WM-115 [nTPM]":"24.1","Blood RNA - basophil [nTPM]":"125.4","Blood RNA - classical monocyte [nTPM]":"89.0","Blood RNA - eosinophil [nTPM]":"82.0","Blood RNA - gdT-cell [nTPM]":"54.5","Blood RNA - intermediate monocyte [nTPM]":"81.6","Blood RNA - MAIT T-cell [nTPM]":"54.3","Blood RNA - memory B-cell [nTPM]":"49.1","Blood RNA - memory CD4 T-cell [nTPM]":"41.0","Blood RNA - memory CD8 T-cell [nTPM]":"51.4","Blood RNA - myeloid DC [nTPM]":"67.1","Blood RNA - naive B-cell [nTPM]":"48.4","Blood RNA - naive CD4 T-cell [nTPM]":"32.0","Blood RNA - naive CD8 T-cell [nTPM]":"36.5","Blood RNA - neutrophil [nTPM]":"88.9","Blood RNA - NK-cell [nTPM]":"83.7","Blood RNA - non-classical monocyte [nTPM]":"97.9","Blood RNA - plasmacytoid DC [nTPM]":"68.0","Blood RNA - T-reg [nTPM]":"65.3","Blood RNA - total PBMC [nTPM]":"72.0","Brain RNA - amygdala [nTPM]":"53.3","Brain RNA - basal ganglia [nTPM]":"59.1","Brain RNA - cerebellum [nTPM]":"56.1","Brain RNA - cerebral cortex [nTPM]":"57.8","Brain RNA - hippocampal formation [nTPM]":"53.6","Brain RNA - hypothalamus [nTPM]":"55.3","Brain RNA - medulla oblongata [nTPM]":"63.8","Brain RNA - midbrain [nTPM]":"61.1","Brain RNA - pons [nTPM]":"58.1","Brain RNA - spinal cord [nTPM]":"57.8","Brain RNA - thalamus [nTPM]":"61.0","Brain RNA - white matter [nTPM]":"52.7","Single Cell Type RNA - Adipocytes [nTPM]":"36.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.6","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"34.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"54.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"49.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"36.5","Single Cell Type RNA - Bipolar cells [nTPM]":"18.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"42.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.6","Single Cell Type RNA - dendritic cells [nTPM]":"56.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"56.7","Single Cell Type RNA - Ductal cells [nTPM]":"71.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.0","Single Cell Type RNA - Endothelial cells [nTPM]":"30.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.8","Single Cell Type RNA - Erythroid cells [nTPM]":"71.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"98.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"56.8","Single Cell Type RNA - Fibroblasts [nTPM]":"50.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.1","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"27.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.0","Single Cell Type RNA - Hepatocytes [nTPM]":"49.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.1","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"38.8","Single Cell Type RNA - Langerhans cells [nTPM]":"44.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"40.4","Single Cell Type RNA - Macrophages [nTPM]":"47.1","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"74.8","Single Cell Type RNA - Muller glia cells [nTPM]":"38.7","Single Cell Type RNA - NK-cells [nTPM]":"68.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"109.6","Single Cell Type RNA - Paneth cells [nTPM]":"44.0","Single Cell Type RNA - Peritubular cells [nTPM]":"32.4","Single Cell Type RNA - Plasma cells [nTPM]":"86.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"67.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"68.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"131.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.5","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"47.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"62.1","Single Cell Type RNA - T-cells [nTPM]":"33.4","Single Cell Type RNA - Theca cells [nTPM]":"48.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.7","Single Cell Type RNA - Urothelial cells [nTPM]":"73.4"},{"Gene":"WDR81","Gene synonym":["CAMRQ2","FLJ33817","PPP1R166","SORF-2"],"Ensembl":"ENSG00000167716","Gene description":"WD repeat domain 81","Uniprot":["Q562E7"],"Chromosome":"17","Position":"1716523-1738599","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"27.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023044","HPA063703"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA023044":"AB_1858822","HPA063703":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.30e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.7","Tissue RNA - adrenal gland [nTPM]":"16.2","Tissue RNA - amygdala [nTPM]":"4.5","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"5.4","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"16.9","Tissue RNA - cerebellum [nTPM]":"4.6","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"6.6","Tissue RNA - colon [nTPM]":"11.5","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"18.9","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"17.4","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"10.9","Tissue RNA - hippocampal formation [nTPM]":"4.3","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"11.9","Tissue RNA - liver [nTPM]":"32.8","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"5.9","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"21.4","Tissue RNA - pancreas [nTPM]":"11.0","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"13.1","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"16.0","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"11.0","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"18.2","Tissue RNA - skin 1 [nTPM]":"18.4","Tissue RNA - small intestine [nTPM]":"17.8","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"24.3","Tissue RNA - stomach 1 [nTPM]":"11.0","Tissue RNA - testis [nTPM]":"7.5","Tissue RNA - thalamus [nTPM]":"6.1","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"10.5","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"15.4","Tissue RNA - vagina [nTPM]":"13.7","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"12.3","Cell RNA - AF22 [nTPM]":"1.7","Cell RNA - AN3-CA [nTPM]":"9.1","Cell RNA - ASC diff [nTPM]":"12.4","Cell RNA - ASC TERT1 [nTPM]":"7.0","Cell RNA - BEWO [nTPM]":"9.2","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"4.4","Cell RNA - Daudi [nTPM]":"4.9","Cell RNA - EFO-21 [nTPM]":"6.5","Cell RNA - fHDF\/TERT166 [nTPM]":"5.4","Cell RNA - GAMG [nTPM]":"6.2","Cell RNA - HaCaT [nTPM]":"12.2","Cell RNA - HAP1 [nTPM]":"6.3","Cell RNA - HBEC3-KT [nTPM]":"8.4","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"9.5","Cell RNA - HEK 293 [nTPM]":"12.8","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"8.8","Cell RNA - Hep G2 [nTPM]":"5.9","Cell RNA - HHSteC [nTPM]":"22.1","Cell RNA - HL-60 [nTPM]":"4.1","Cell RNA - HMC-1 [nTPM]":"7.6","Cell RNA - HSkMC [nTPM]":"17.8","Cell RNA - hTCEpi [nTPM]":"8.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.9","Cell RNA - hTERT-HME1 [nTPM]":"4.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.9","Cell RNA - HUVEC TERT2 [nTPM]":"5.0","Cell RNA - JURKAT [nTPM]":"3.7","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"6.3","Cell RNA - LHCN-M2 [nTPM]":"7.6","Cell RNA - MCF7 [nTPM]":"6.8","Cell RNA - MOLT-4 [nTPM]":"1.3","Cell RNA - NB-4 [nTPM]":"7.6","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"4.2","Cell RNA - PC-3 [nTPM]":"9.4","Cell RNA - REH [nTPM]":"6.4","Cell RNA - RH-30 [nTPM]":"2.9","Cell RNA - RPMI-8226 [nTPM]":"6.8","Cell RNA - RPTEC TERT1 [nTPM]":"3.7","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"5.0","Cell RNA - SiHa [nTPM]":"4.3","Cell RNA - SK-BR-3 [nTPM]":"3.4","Cell RNA - SK-MEL-30 [nTPM]":"15.4","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"6.0","Cell RNA - THP-1 [nTPM]":"6.1","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"7.9","Cell RNA - U-251 MG [nTPM]":"6.7","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"1.3","Cell RNA - U-698 [nTPM]":"3.1","Cell RNA - U-87 MG [nTPM]":"7.7","Cell RNA - U-937 [nTPM]":"5.9","Cell RNA - WM-115 [nTPM]":"2.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"4.5","Brain RNA - basal ganglia [nTPM]":"5.4","Brain RNA - cerebellum [nTPM]":"4.6","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"4.3","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"5.9","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"6.1","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"6.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.3","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"4.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - dendritic cells [nTPM]":"9.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"8.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"27.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"22.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"15.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"7.5","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.8","Single Cell Type RNA - Paneth cells [nTPM]":"4.8","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"5.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"5.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"WFS1","Gene synonym":["DFNA14","DFNA38","DFNA6","DIDMOAD","WFS"],"Ensembl":"ENSG00000109501","Gene description":"Wolframin ER transmembrane glycoprotein","Uniprot":["O76024"],"Chromosome":"4","Position":"6269849-6303265","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Deafness","Diabetes insipidus","Diabetes mellitus","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"131.4","Extravillous trophoblasts":"120.2","Granulosa cells":"71.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"100.4","Hep G2":"83.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029128"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029128":"AB_10603460"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.13e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"39.4","Tissue RNA - adrenal gland [nTPM]":"20.2","Tissue RNA - amygdala [nTPM]":"43.7","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"71.2","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"36.0","Tissue RNA - cerebellum [nTPM]":"34.3","Tissue RNA - cerebral cortex [nTPM]":"47.2","Tissue RNA - cervix [nTPM]":"51.9","Tissue RNA - choroid plexus [nTPM]":"34.5","Tissue RNA - colon [nTPM]":"44.8","Tissue RNA - duodenum [nTPM]":"12.2","Tissue RNA - endometrium 1 [nTPM]":"75.4","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"58.6","Tissue RNA - gallbladder [nTPM]":"12.4","Tissue RNA - heart muscle [nTPM]":"64.3","Tissue RNA - hippocampal formation [nTPM]":"35.9","Tissue RNA - hypothalamus [nTPM]":"36.8","Tissue RNA - kidney [nTPM]":"16.8","Tissue RNA - liver [nTPM]":"17.1","Tissue RNA - lung [nTPM]":"43.8","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"34.4","Tissue RNA - midbrain [nTPM]":"43.7","Tissue RNA - ovary [nTPM]":"87.1","Tissue RNA - pancreas [nTPM]":"20.1","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"50.2","Tissue RNA - placenta [nTPM]":"16.6","Tissue RNA - pons [nTPM]":"36.6","Tissue RNA - prostate [nTPM]":"34.6","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"14.6","Tissue RNA - seminal vesicle [nTPM]":"36.3","Tissue RNA - skeletal muscle [nTPM]":"16.0","Tissue RNA - skin 1 [nTPM]":"26.8","Tissue RNA - small intestine [nTPM]":"22.0","Tissue RNA - smooth muscle [nTPM]":"17.0","Tissue RNA - spinal cord [nTPM]":"33.7","Tissue RNA - spleen [nTPM]":"29.3","Tissue RNA - stomach 1 [nTPM]":"29.1","Tissue RNA - testis [nTPM]":"31.8","Tissue RNA - thalamus [nTPM]":"44.1","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"48.1","Tissue RNA - tongue [nTPM]":"7.5","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"57.8","Tissue RNA - vagina [nTPM]":"29.1","Tissue RNA - white matter [nTPM]":"32.1","Cell RNA - A-431 [nTPM]":"14.1","Cell RNA - A549 [nTPM]":"35.3","Cell RNA - AF22 [nTPM]":"9.1","Cell RNA - AN3-CA [nTPM]":"33.9","Cell RNA - ASC diff [nTPM]":"37.2","Cell RNA - ASC TERT1 [nTPM]":"10.2","Cell RNA - BEWO [nTPM]":"100.4","Cell RNA - BJ [nTPM]":"23.0","Cell RNA - BJ hTERT+ [nTPM]":"32.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.6","Cell RNA - CACO-2 [nTPM]":"24.8","Cell RNA - CAPAN-2 [nTPM]":"37.2","Cell RNA - Daudi [nTPM]":"5.5","Cell RNA - EFO-21 [nTPM]":"34.3","Cell RNA - fHDF\/TERT166 [nTPM]":"26.3","Cell RNA - GAMG [nTPM]":"74.8","Cell RNA - HaCaT [nTPM]":"8.0","Cell RNA - HAP1 [nTPM]":"6.8","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"6.4","Cell RNA - HDLM-2 [nTPM]":"5.7","Cell RNA - HEK 293 [nTPM]":"14.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"11.0","Cell RNA - Hep G2 [nTPM]":"83.0","Cell RNA - HHSteC [nTPM]":"34.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"33.7","Cell RNA - hTCEpi [nTPM]":"18.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.0","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"12.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.3","Cell RNA - JURKAT [nTPM]":"2.5","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"24.3","Cell RNA - LHCN-M2 [nTPM]":"9.7","Cell RNA - MCF7 [nTPM]":"28.0","Cell RNA - MOLT-4 [nTPM]":"1.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"13.5","Cell RNA - OE19 [nTPM]":"20.3","Cell RNA - PC-3 [nTPM]":"38.0","Cell RNA - REH [nTPM]":"3.4","Cell RNA - RH-30 [nTPM]":"9.6","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"52.4","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"15.4","Cell RNA - SiHa [nTPM]":"12.2","Cell RNA - SK-BR-3 [nTPM]":"17.4","Cell RNA - SK-MEL-30 [nTPM]":"13.1","Cell RNA - SuSa [nTPM]":"9.6","Cell RNA - T-47d [nTPM]":"31.5","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"19.9","Cell RNA - U-138 MG [nTPM]":"19.8","Cell RNA - U-2 OS [nTPM]":"22.8","Cell RNA - U-2197 [nTPM]":"19.1","Cell RNA - U-251 MG [nTPM]":"14.8","Cell RNA - U-266\/70 [nTPM]":"26.0","Cell RNA - U-266\/84 [nTPM]":"10.1","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"23.9","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"18.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"3.9","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"43.7","Brain RNA - basal ganglia [nTPM]":"71.2","Brain RNA - cerebellum [nTPM]":"34.3","Brain RNA - cerebral cortex [nTPM]":"47.2","Brain RNA - hippocampal formation [nTPM]":"35.9","Brain RNA - hypothalamus [nTPM]":"36.8","Brain RNA - medulla oblongata [nTPM]":"34.4","Brain RNA - midbrain [nTPM]":"43.7","Brain RNA - pons [nTPM]":"36.6","Brain RNA - spinal cord [nTPM]":"33.7","Brain RNA - thalamus [nTPM]":"44.1","Brain RNA - white matter [nTPM]":"32.1","Single Cell Type RNA - Adipocytes [nTPM]":"38.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"131.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"40.5","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"42.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"10.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.6","Single Cell Type RNA - Endothelial cells [nTPM]":"21.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"120.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"71.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"19.1","Single Cell Type RNA - Leydig cells [nTPM]":"40.0","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"31.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"57.9","Single Cell Type RNA - Plasma cells [nTPM]":"19.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.7","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"11.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"WHRN","Gene synonym":["CIP98","DFNB31","PDZD7B","USH2D"],"Ensembl":"ENSG00000095397","Gene description":"Whirlin","Uniprot":["Q9P202"],"Chromosome":"9","Position":"114402080-114505473","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"104.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"49.5","Endometrial stromal cells":"13.9","Glandular and luminal cells":"39.6","Plasma cells":"14.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"97.9","U-266\/70":"67.8","U-266\/84":"89.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"104.7","Tissue RNA - amygdala [nTPM]":"21.7","Tissue RNA - appendix [nTPM]":"2.3","Tissue RNA - basal ganglia [nTPM]":"33.5","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"5.9","Tissue RNA - cerebellum [nTPM]":"24.0","Tissue RNA - cerebral cortex [nTPM]":"28.9","Tissue RNA - cervix [nTPM]":"17.8","Tissue RNA - choroid plexus [nTPM]":"47.2","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"36.4","Tissue RNA - epididymis [nTPM]":"4.1","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"11.5","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"8.1","Tissue RNA - hippocampal formation [nTPM]":"21.7","Tissue RNA - hypothalamus [nTPM]":"29.3","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"4.8","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"37.2","Tissue RNA - midbrain [nTPM]":"27.5","Tissue RNA - ovary [nTPM]":"20.5","Tissue RNA - pancreas [nTPM]":"14.1","Tissue RNA - parathyroid gland [nTPM]":"7.1","Tissue RNA - pituitary gland [nTPM]":"36.8","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"41.4","Tissue RNA - prostate [nTPM]":"13.8","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"8.7","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"8.9","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"24.2","Tissue RNA - spleen [nTPM]":"20.7","Tissue RNA - stomach 1 [nTPM]":"7.9","Tissue RNA - testis [nTPM]":"50.1","Tissue RNA - thalamus [nTPM]":"31.5","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"10.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"7.2","Tissue RNA - white matter [nTPM]":"58.7","Cell RNA - A-431 [nTPM]":"2.0","Cell RNA - A549 [nTPM]":"2.0","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"11.3","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"5.2","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.9","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"16.2","Cell RNA - HaCaT [nTPM]":"5.3","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"31.0","Cell RNA - HEK 293 [nTPM]":"7.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"23.4","Cell RNA - Hep G2 [nTPM]":"3.1","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"1.0","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.3","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"6.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"2.6","Cell RNA - K-562 [nTPM]":"9.6","Cell RNA - Karpas-707 [nTPM]":"97.9","Cell RNA - LHCN-M2 [nTPM]":"1.4","Cell RNA - MCF7 [nTPM]":"14.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"18.1","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"32.3","Cell RNA - RPTEC TERT1 [nTPM]":"3.8","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"14.9","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"6.8","Cell RNA - SK-BR-3 [nTPM]":"10.2","Cell RNA - SK-MEL-30 [nTPM]":"29.7","Cell RNA - SuSa [nTPM]":"3.2","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"3.4","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"4.3","Cell RNA - U-251 MG [nTPM]":"5.6","Cell RNA - U-266\/70 [nTPM]":"67.8","Cell RNA - U-266\/84 [nTPM]":"89.6","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"2.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"21.7","Brain RNA - basal ganglia [nTPM]":"33.5","Brain RNA - cerebellum [nTPM]":"24.0","Brain RNA - cerebral cortex [nTPM]":"28.9","Brain RNA - hippocampal formation [nTPM]":"21.7","Brain RNA - hypothalamus [nTPM]":"29.3","Brain RNA - medulla oblongata [nTPM]":"37.2","Brain RNA - midbrain [nTPM]":"27.5","Brain RNA - pons [nTPM]":"41.4","Brain RNA - spinal cord [nTPM]":"24.2","Brain RNA - thalamus [nTPM]":"31.5","Brain RNA - white matter [nTPM]":"58.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"49.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.6","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"14.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"7.8","Single Cell Type RNA - Theca cells [nTPM]":"7.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"WNK1","Gene synonym":["HSAN2","HSN2","PPP1R167","PRKWNK1"],"Ensembl":"ENSG00000060237","Gene description":"WNK lysine deficient protein kinase 1","Uniprot":["Q9H4A3"],"Chromosome":"12","Position":"752579-911452","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Protein kinase inhibitor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"293.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"336.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046541","HPA059157"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"92000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046541":"AB_2679690","HPA059157":"AB_2683935"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.67e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"56.7","Tissue RNA - adrenal gland [nTPM]":"20.6","Tissue RNA - amygdala [nTPM]":"190.8","Tissue RNA - appendix [nTPM]":"36.4","Tissue RNA - basal ganglia [nTPM]":"236.8","Tissue RNA - bone marrow [nTPM]":"54.2","Tissue RNA - breast [nTPM]":"33.5","Tissue RNA - cerebellum [nTPM]":"179.4","Tissue RNA - cerebral cortex [nTPM]":"166.1","Tissue RNA - cervix [nTPM]":"32.8","Tissue RNA - choroid plexus [nTPM]":"110.8","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"14.4","Tissue RNA - endometrium 1 [nTPM]":"26.7","Tissue RNA - epididymis [nTPM]":"30.4","Tissue RNA - esophagus [nTPM]":"72.1","Tissue RNA - fallopian tube [nTPM]":"29.4","Tissue RNA - gallbladder [nTPM]":"27.1","Tissue RNA - heart muscle [nTPM]":"63.8","Tissue RNA - hippocampal formation [nTPM]":"132.3","Tissue RNA - hypothalamus [nTPM]":"161.1","Tissue RNA - kidney [nTPM]":"84.0","Tissue RNA - liver [nTPM]":"31.6","Tissue RNA - lung [nTPM]":"44.6","Tissue RNA - lymph node [nTPM]":"39.2","Tissue RNA - medulla oblongata [nTPM]":"232.3","Tissue RNA - midbrain [nTPM]":"238.4","Tissue RNA - ovary [nTPM]":"30.1","Tissue RNA - pancreas [nTPM]":"22.5","Tissue RNA - parathyroid gland [nTPM]":"51.1","Tissue RNA - pituitary gland [nTPM]":"17.0","Tissue RNA - placenta [nTPM]":"36.0","Tissue RNA - pons [nTPM]":"217.0","Tissue RNA - prostate [nTPM]":"29.7","Tissue RNA - rectum [nTPM]":"24.2","Tissue RNA - retina [nTPM]":"87.4","Tissue RNA - salivary gland [nTPM]":"24.0","Tissue RNA - seminal vesicle [nTPM]":"33.4","Tissue RNA - skeletal muscle [nTPM]":"79.7","Tissue RNA - skin 1 [nTPM]":"52.0","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"36.1","Tissue RNA - spinal cord [nTPM]":"225.4","Tissue RNA - spleen [nTPM]":"30.2","Tissue RNA - stomach 1 [nTPM]":"27.6","Tissue RNA - testis [nTPM]":"48.3","Tissue RNA - thalamus [nTPM]":"238.0","Tissue RNA - thymus [nTPM]":"61.3","Tissue RNA - thyroid gland [nTPM]":"27.7","Tissue RNA - tongue [nTPM]":"79.8","Tissue RNA - tonsil [nTPM]":"46.9","Tissue RNA - urinary bladder [nTPM]":"35.8","Tissue RNA - vagina [nTPM]":"43.8","Tissue RNA - white matter [nTPM]":"293.0","Cell RNA - A-431 [nTPM]":"53.9","Cell RNA - A549 [nTPM]":"97.5","Cell RNA - AF22 [nTPM]":"131.8","Cell RNA - AN3-CA [nTPM]":"11.3","Cell RNA - ASC diff [nTPM]":"88.1","Cell RNA - ASC TERT1 [nTPM]":"80.0","Cell RNA - BEWO [nTPM]":"52.2","Cell RNA - BJ [nTPM]":"48.3","Cell RNA - BJ hTERT+ [nTPM]":"61.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"58.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.3","Cell RNA - CACO-2 [nTPM]":"59.4","Cell RNA - CAPAN-2 [nTPM]":"55.7","Cell RNA - Daudi [nTPM]":"71.0","Cell RNA - EFO-21 [nTPM]":"16.8","Cell RNA - fHDF\/TERT166 [nTPM]":"107.8","Cell RNA - GAMG [nTPM]":"73.5","Cell RNA - HaCaT [nTPM]":"39.8","Cell RNA - HAP1 [nTPM]":"93.8","Cell RNA - HBEC3-KT [nTPM]":"56.7","Cell RNA - HBF TERT88 [nTPM]":"84.3","Cell RNA - HDLM-2 [nTPM]":"124.7","Cell RNA - HEK 293 [nTPM]":"51.4","Cell RNA - HEL [nTPM]":"169.4","Cell RNA - HeLa [nTPM]":"122.2","Cell RNA - Hep G2 [nTPM]":"46.1","Cell RNA - HHSteC [nTPM]":"66.7","Cell RNA - HL-60 [nTPM]":"86.9","Cell RNA - HMC-1 [nTPM]":"68.2","Cell RNA - HSkMC [nTPM]":"64.0","Cell RNA - hTCEpi [nTPM]":"82.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"97.6","Cell RNA - hTERT-HME1 [nTPM]":"164.4","Cell RNA - hTERT-RPE1 [nTPM]":"61.6","Cell RNA - HUVEC TERT2 [nTPM]":"73.4","Cell RNA - JURKAT [nTPM]":"68.0","Cell RNA - K-562 [nTPM]":"76.4","Cell RNA - Karpas-707 [nTPM]":"158.2","Cell RNA - LHCN-M2 [nTPM]":"77.8","Cell RNA - MCF7 [nTPM]":"54.1","Cell RNA - MOLT-4 [nTPM]":"154.6","Cell RNA - NB-4 [nTPM]":"15.6","Cell RNA - NTERA-2 [nTPM]":"105.8","Cell RNA - OE19 [nTPM]":"47.8","Cell RNA - PC-3 [nTPM]":"24.3","Cell RNA - REH [nTPM]":"78.0","Cell RNA - RH-30 [nTPM]":"138.8","Cell RNA - RPMI-8226 [nTPM]":"20.8","Cell RNA - RPTEC TERT1 [nTPM]":"80.6","Cell RNA - RT4 [nTPM]":"96.8","Cell RNA - SCLC-21H [nTPM]":"35.1","Cell RNA - SH-SY5Y [nTPM]":"40.7","Cell RNA - SiHa [nTPM]":"121.8","Cell RNA - SK-BR-3 [nTPM]":"82.9","Cell RNA - SK-MEL-30 [nTPM]":"33.6","Cell RNA - SuSa [nTPM]":"183.3","Cell RNA - T-47d [nTPM]":"86.8","Cell RNA - THP-1 [nTPM]":"97.2","Cell RNA - TIME [nTPM]":"78.3","Cell RNA - U-138 MG [nTPM]":"67.1","Cell RNA - U-2 OS [nTPM]":"77.3","Cell RNA - U-2197 [nTPM]":"86.2","Cell RNA - U-251 MG [nTPM]":"70.8","Cell RNA - U-266\/70 [nTPM]":"23.8","Cell RNA - U-266\/84 [nTPM]":"43.1","Cell RNA - U-698 [nTPM]":"103.8","Cell RNA - U-87 MG [nTPM]":"59.4","Cell RNA - U-937 [nTPM]":"44.6","Cell RNA - WM-115 [nTPM]":"53.2","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"5.6","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"3.4","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"190.8","Brain RNA - basal ganglia [nTPM]":"236.8","Brain RNA - cerebellum [nTPM]":"179.4","Brain RNA - cerebral cortex [nTPM]":"166.1","Brain RNA - hippocampal formation [nTPM]":"132.3","Brain RNA - hypothalamus [nTPM]":"161.1","Brain RNA - medulla oblongata [nTPM]":"232.3","Brain RNA - midbrain [nTPM]":"238.4","Brain RNA - pons [nTPM]":"217.0","Brain RNA - spinal cord [nTPM]":"225.4","Brain RNA - thalamus [nTPM]":"238.0","Brain RNA - white matter [nTPM]":"293.0","Single Cell Type RNA - Adipocytes [nTPM]":"261.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"102.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"141.6","Single Cell Type RNA - Astrocytes [nTPM]":"77.1","Single Cell Type RNA - B-cells [nTPM]":"65.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"112.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"85.4","Single Cell Type RNA - Bipolar cells [nTPM]":"87.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"50.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"241.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"47.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"90.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"150.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.5","Single Cell Type RNA - dendritic cells [nTPM]":"83.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"86.1","Single Cell Type RNA - Ductal cells [nTPM]":"28.0","Single Cell Type RNA - Early spermatids [nTPM]":"29.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"63.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"68.6","Single Cell Type RNA - Endothelial cells [nTPM]":"106.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"58.7","Single Cell Type RNA - Erythroid cells [nTPM]":"304.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"182.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.9","Single Cell Type RNA - Fibroblasts [nTPM]":"58.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"70.2","Single Cell Type RNA - granulocytes [nTPM]":"52.6","Single Cell Type RNA - Granulosa cells [nTPM]":"46.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"52.5","Single Cell Type RNA - Hepatocytes [nTPM]":"71.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"57.3","Single Cell Type RNA - Horizontal cells [nTPM]":"84.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"165.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.3","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"121.4","Single Cell Type RNA - Langerhans cells [nTPM]":"80.8","Single Cell Type RNA - Late spermatids [nTPM]":"21.2","Single Cell Type RNA - Leydig cells [nTPM]":"61.8","Single Cell Type RNA - Macrophages [nTPM]":"96.7","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"114.3","Single Cell Type RNA - monocytes [nTPM]":"95.7","Single Cell Type RNA - Muller glia cells [nTPM]":"64.0","Single Cell Type RNA - NK-cells [nTPM]":"61.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"126.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"336.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"41.7","Single Cell Type RNA - Paneth cells [nTPM]":"34.8","Single Cell Type RNA - Peritubular cells [nTPM]":"55.7","Single Cell Type RNA - Plasma cells [nTPM]":"76.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"59.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"64.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"96.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"69.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"63.8","Single Cell Type RNA - Spermatocytes [nTPM]":"186.5","Single Cell Type RNA - Spermatogonia [nTPM]":"74.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"147.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"136.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.5","Single Cell Type RNA - T-cells [nTPM]":"112.9","Single Cell Type RNA - Theca cells [nTPM]":"33.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.8","Single Cell Type RNA - Urothelial cells [nTPM]":"55.2"},{"Gene":"WWOX","Gene synonym":["FOR","SDR41C1","WOX1"],"Ensembl":"ENSG00000186153","Gene description":"WW domain containing oxidoreductase","Uniprot":["Q9NZC7"],"Chromosome":"16","Position":"78099430-79212667","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Wnt signaling pathway"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Astrocytes":"927.8","Excitatory neurons":"270.5","Inhibitory neurons":"540.9","Microglial cells":"471.2","Oligodendrocyte precursor cells":"914.9","Oligodendrocytes":"793.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"85.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050992"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA050992":"AB_2681299"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.07e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.6","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"18.6","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"23.9","Tissue RNA - bone marrow [nTPM]":"4.2","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"24.0","Tissue RNA - cerebral cortex [nTPM]":"20.3","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"21.2","Tissue RNA - colon [nTPM]":"5.2","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"10.1","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"9.0","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"18.8","Tissue RNA - hypothalamus [nTPM]":"22.5","Tissue RNA - kidney [nTPM]":"12.7","Tissue RNA - liver [nTPM]":"12.0","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"24.0","Tissue RNA - midbrain [nTPM]":"22.4","Tissue RNA - ovary [nTPM]":"7.6","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"12.1","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"25.3","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"6.4","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"22.0","Tissue RNA - spleen [nTPM]":"4.7","Tissue RNA - stomach 1 [nTPM]":"6.0","Tissue RNA - testis [nTPM]":"9.3","Tissue RNA - thalamus [nTPM]":"21.0","Tissue RNA - thymus [nTPM]":"9.0","Tissue RNA - thyroid gland [nTPM]":"21.8","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"6.0","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"30.0","Cell RNA - A-431 [nTPM]":"11.1","Cell RNA - A549 [nTPM]":"9.5","Cell RNA - AF22 [nTPM]":"9.2","Cell RNA - AN3-CA [nTPM]":"7.7","Cell RNA - ASC diff [nTPM]":"11.0","Cell RNA - ASC TERT1 [nTPM]":"5.3","Cell RNA - BEWO [nTPM]":"11.1","Cell RNA - BJ [nTPM]":"1.6","Cell RNA - BJ hTERT+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.2","Cell RNA - CACO-2 [nTPM]":"7.0","Cell RNA - CAPAN-2 [nTPM]":"9.6","Cell RNA - Daudi [nTPM]":"19.5","Cell RNA - EFO-21 [nTPM]":"8.6","Cell RNA - fHDF\/TERT166 [nTPM]":"1.5","Cell RNA - GAMG [nTPM]":"5.2","Cell RNA - HaCaT [nTPM]":"10.0","Cell RNA - HAP1 [nTPM]":"5.1","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"2.6","Cell RNA - HDLM-2 [nTPM]":"11.0","Cell RNA - HEK 293 [nTPM]":"26.8","Cell RNA - HEL [nTPM]":"6.0","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"15.7","Cell RNA - HHSteC [nTPM]":"7.5","Cell RNA - HL-60 [nTPM]":"16.7","Cell RNA - HMC-1 [nTPM]":"3.4","Cell RNA - HSkMC [nTPM]":"5.9","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.3","Cell RNA - hTERT-HME1 [nTPM]":"2.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"4.4","Cell RNA - JURKAT [nTPM]":"25.9","Cell RNA - K-562 [nTPM]":"9.2","Cell RNA - Karpas-707 [nTPM]":"4.2","Cell RNA - LHCN-M2 [nTPM]":"2.6","Cell RNA - MCF7 [nTPM]":"85.7","Cell RNA - MOLT-4 [nTPM]":"27.7","Cell RNA - NB-4 [nTPM]":"21.9","Cell RNA - NTERA-2 [nTPM]":"8.6","Cell RNA - OE19 [nTPM]":"5.9","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"32.2","Cell RNA - RH-30 [nTPM]":"3.9","Cell RNA - RPMI-8226 [nTPM]":"19.1","Cell RNA - RPTEC TERT1 [nTPM]":"5.3","Cell RNA - RT4 [nTPM]":"3.9","Cell RNA - SCLC-21H [nTPM]":"17.6","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"11.9","Cell RNA - SK-MEL-30 [nTPM]":"4.0","Cell RNA - SuSa [nTPM]":"9.3","Cell RNA - T-47d [nTPM]":"12.8","Cell RNA - THP-1 [nTPM]":"12.0","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"2.7","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"2.2","Cell RNA - U-251 MG [nTPM]":"6.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"18.3","Cell RNA - U-698 [nTPM]":"41.2","Cell RNA - U-87 MG [nTPM]":"10.4","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"4.6","Blood RNA - basophil [nTPM]":"7.0","Blood RNA - classical monocyte [nTPM]":"9.1","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"11.4","Blood RNA - intermediate monocyte [nTPM]":"7.9","Blood RNA - MAIT T-cell [nTPM]":"13.4","Blood RNA - memory B-cell [nTPM]":"9.3","Blood RNA - memory CD4 T-cell [nTPM]":"8.2","Blood RNA - memory CD8 T-cell [nTPM]":"9.1","Blood RNA - myeloid DC [nTPM]":"7.7","Blood RNA - naive B-cell [nTPM]":"6.6","Blood RNA - naive CD4 T-cell [nTPM]":"8.4","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"9.1","Blood RNA - non-classical monocyte [nTPM]":"5.8","Blood RNA - plasmacytoid DC [nTPM]":"14.5","Blood RNA - T-reg [nTPM]":"13.5","Blood RNA - total PBMC [nTPM]":"6.0","Brain RNA - amygdala [nTPM]":"18.6","Brain RNA - basal ganglia [nTPM]":"23.9","Brain RNA - cerebellum [nTPM]":"24.0","Brain RNA - cerebral cortex [nTPM]":"20.3","Brain RNA - hippocampal formation [nTPM]":"18.8","Brain RNA - hypothalamus [nTPM]":"22.5","Brain RNA - medulla oblongata [nTPM]":"24.0","Brain RNA - midbrain [nTPM]":"22.4","Brain RNA - pons [nTPM]":"25.3","Brain RNA - spinal cord [nTPM]":"22.0","Brain RNA - thalamus [nTPM]":"21.0","Brain RNA - white matter [nTPM]":"30.0","Single Cell Type RNA - Adipocytes [nTPM]":"12.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"927.8","Single Cell Type RNA - B-cells [nTPM]":"9.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"7.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"13.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.7","Single Cell Type RNA - dendritic cells [nTPM]":"10.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"12.4","Single Cell Type RNA - Early spermatids [nTPM]":"43.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.9","Single Cell Type RNA - Endothelial cells [nTPM]":"9.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"13.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"270.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.9","Single Cell Type RNA - Fibroblasts [nTPM]":"12.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.6","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"18.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"18.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"540.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"38.2","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"471.2","Single Cell Type RNA - monocytes [nTPM]":"5.9","Single Cell Type RNA - Muller glia cells [nTPM]":"46.3","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"914.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"793.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.5","Single Cell Type RNA - Paneth cells [nTPM]":"5.9","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"18.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.8","Single Cell Type RNA - Spermatocytes [nTPM]":"19.7","Single Cell Type RNA - Spermatogonia [nTPM]":"17.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - T-cells [nTPM]":"9.9","Single Cell Type RNA - Theca cells [nTPM]":"12.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.8","Single Cell Type RNA - Urothelial cells [nTPM]":"13.0"},{"Gene":"XK","Gene synonym":["Kx","NA","NAC","X1k","XKR1"],"Ensembl":"ENSG00000047597","Gene description":"X-linked Kx blood group","Uniprot":["P51811"],"Chromosome":"X","Position":"37685791-37732130","Protein class":["Blood group antigen proteins","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":["Blood group antigen"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"14.2","intestine":"12.2","stomach 1":"11.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"26.7","Erythroid cells":"63.5","Gastric mucus-secreting cells":"17.9","Proximal enterocytes":"21.5","Undifferentiated cells":"14.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"6.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"53","RNA blood cell specific nTPM":{"basophil":"10.2","eosinophil":"5.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"102","RNA blood lineage specific nTPM":{"granulocytes":"10.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"44.4","HL-60":"23.2","K-562":"29.1","NB-4":"21.1","RPMI-8226":"20.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019036"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA019036":"AB_1846286"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"14.2","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"12.2","Tissue RNA - duodenum [nTPM]":"10.8","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"3.8","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"11.2","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"5.4","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"10.6","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"11.5","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"17.4","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"15.9","Cell RNA - Daudi [nTPM]":"14.7","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.8","Cell RNA - HaCaT [nTPM]":"2.7","Cell RNA - HAP1 [nTPM]":"15.4","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.2","Cell RNA - HEL [nTPM]":"44.4","Cell RNA - HeLa [nTPM]":"2.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"23.2","Cell RNA - HMC-1 [nTPM]":"3.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"29.1","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"1.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"21.1","Cell RNA - NTERA-2 [nTPM]":"5.5","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"5.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"20.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"4.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"2.1","Cell RNA - THP-1 [nTPM]":"5.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"9.3","Cell RNA - U-266\/84 [nTPM]":"16.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"12.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"10.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"5.8","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"63.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"9.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"2.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"XPR1","Gene synonym":["SLC53A1","SYG1","X3"],"Ensembl":"ENSG00000143324","Gene description":"Xenotropic and polytropic retrovirus receptor 1","Uniprot":["Q9UBH6"],"Chromosome":"1","Position":"180632022-180890279","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"100.9","Excitatory neurons":"118.2","Inhibitory neurons":"102.5","Microglial cells":"102.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SH-SY5Y":"145.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016557"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016557":"AB_2669382"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.04e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.7","Tissue RNA - adrenal gland [nTPM]":"9.0","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"6.2","Tissue RNA - breast [nTPM]":"6.6","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"19.3","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"9.2","Tissue RNA - duodenum [nTPM]":"11.0","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"7.4","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"15.3","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"30.3","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"20.3","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"10.1","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"8.7","Tissue RNA - ovary [nTPM]":"7.3","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"20.3","Tissue RNA - pituitary gland [nTPM]":"6.1","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"6.5","Tissue RNA - rectum [nTPM]":"9.9","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"10.1","Tissue RNA - skeletal muscle [nTPM]":"5.4","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"11.0","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"5.5","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"16.7","Tissue RNA - thalamus [nTPM]":"11.5","Tissue RNA - thymus [nTPM]":"8.5","Tissue RNA - thyroid gland [nTPM]":"13.6","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"16.1","Cell RNA - A549 [nTPM]":"22.6","Cell RNA - AF22 [nTPM]":"54.4","Cell RNA - AN3-CA [nTPM]":"19.1","Cell RNA - ASC diff [nTPM]":"17.9","Cell RNA - ASC TERT1 [nTPM]":"24.1","Cell RNA - BEWO [nTPM]":"51.5","Cell RNA - BJ [nTPM]":"18.2","Cell RNA - BJ hTERT+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.9","Cell RNA - CACO-2 [nTPM]":"32.6","Cell RNA - CAPAN-2 [nTPM]":"23.2","Cell RNA - Daudi [nTPM]":"15.2","Cell RNA - EFO-21 [nTPM]":"42.3","Cell RNA - fHDF\/TERT166 [nTPM]":"21.1","Cell RNA - GAMG [nTPM]":"19.2","Cell RNA - HaCaT [nTPM]":"42.7","Cell RNA - HAP1 [nTPM]":"22.0","Cell RNA - HBEC3-KT [nTPM]":"32.3","Cell RNA - HBF TERT88 [nTPM]":"17.8","Cell RNA - HDLM-2 [nTPM]":"21.4","Cell RNA - HEK 293 [nTPM]":"14.1","Cell RNA - HEL [nTPM]":"19.7","Cell RNA - HeLa [nTPM]":"15.0","Cell RNA - Hep G2 [nTPM]":"23.3","Cell RNA - HHSteC [nTPM]":"20.9","Cell RNA - HL-60 [nTPM]":"16.6","Cell RNA - HMC-1 [nTPM]":"20.7","Cell RNA - HSkMC [nTPM]":"20.2","Cell RNA - hTCEpi [nTPM]":"31.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.2","Cell RNA - hTERT-HME1 [nTPM]":"35.5","Cell RNA - hTERT-RPE1 [nTPM]":"19.7","Cell RNA - HUVEC TERT2 [nTPM]":"26.7","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"61.3","Cell RNA - Karpas-707 [nTPM]":"24.7","Cell RNA - LHCN-M2 [nTPM]":"28.8","Cell RNA - MCF7 [nTPM]":"14.7","Cell RNA - MOLT-4 [nTPM]":"15.9","Cell RNA - NB-4 [nTPM]":"7.6","Cell RNA - NTERA-2 [nTPM]":"51.4","Cell RNA - OE19 [nTPM]":"20.3","Cell RNA - PC-3 [nTPM]":"4.9","Cell RNA - REH [nTPM]":"16.6","Cell RNA - RH-30 [nTPM]":"19.5","Cell RNA - RPMI-8226 [nTPM]":"20.2","Cell RNA - RPTEC TERT1 [nTPM]":"30.8","Cell RNA - RT4 [nTPM]":"32.8","Cell RNA - SCLC-21H [nTPM]":"34.6","Cell RNA - SH-SY5Y [nTPM]":"145.7","Cell RNA - SiHa [nTPM]":"25.0","Cell RNA - SK-BR-3 [nTPM]":"22.0","Cell RNA - SK-MEL-30 [nTPM]":"16.0","Cell RNA - SuSa [nTPM]":"37.0","Cell RNA - T-47d [nTPM]":"19.5","Cell RNA - THP-1 [nTPM]":"18.8","Cell RNA - TIME [nTPM]":"22.3","Cell RNA - U-138 MG [nTPM]":"15.9","Cell RNA - U-2 OS [nTPM]":"15.3","Cell RNA - U-2197 [nTPM]":"22.9","Cell RNA - U-251 MG [nTPM]":"23.1","Cell RNA - U-266\/70 [nTPM]":"27.3","Cell RNA - U-266\/84 [nTPM]":"27.5","Cell RNA - U-698 [nTPM]":"29.9","Cell RNA - U-87 MG [nTPM]":"11.5","Cell RNA - U-937 [nTPM]":"16.3","Cell RNA - WM-115 [nTPM]":"26.4","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"4.5","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"3.8","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"4.3","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"13.4","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"8.7","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"5.5","Brain RNA - thalamus [nTPM]":"11.5","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.4","Single Cell Type RNA - Astrocytes [nTPM]":"100.9","Single Cell Type RNA - B-cells [nTPM]":"11.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"55.8","Single Cell Type RNA - Bipolar cells [nTPM]":"16.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"47.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"15.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.7","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"22.3","Single Cell Type RNA - Early spermatids [nTPM]":"19.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.3","Single Cell Type RNA - Endothelial cells [nTPM]":"21.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"118.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.6","Single Cell Type RNA - Fibroblasts [nTPM]":"10.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.2","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"11.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"11.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.8","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"102.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.0","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"21.4","Single Cell Type RNA - Langerhans cells [nTPM]":"17.7","Single Cell Type RNA - Late spermatids [nTPM]":"9.7","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"14.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"102.1","Single Cell Type RNA - monocytes [nTPM]":"9.7","Single Cell Type RNA - Muller glia cells [nTPM]":"8.1","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"79.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.5","Single Cell Type RNA - Paneth cells [nTPM]":"12.4","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.5","Single Cell Type RNA - Spermatocytes [nTPM]":"15.5","Single Cell Type RNA - Spermatogonia [nTPM]":"17.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - T-cells [nTPM]":"13.4","Single Cell Type RNA - Theca cells [nTPM]":"10.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"14.1"},{"Gene":"XRCC1","Gene synonym":["RCC"],"Ensembl":"ENSG00000073050","Gene description":"X-ray repair cross complementing 1","Uniprot":["P18887"],"Chromosome":"19","Position":"43543311-43580473","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005427","HPA006717"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB005427":"AB_2215661","HPA006717":"AB_1858896"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.33e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.5","Tissue RNA - adrenal gland [nTPM]":"16.4","Tissue RNA - amygdala [nTPM]":"15.3","Tissue RNA - appendix [nTPM]":"18.0","Tissue RNA - basal ganglia [nTPM]":"15.6","Tissue RNA - bone marrow [nTPM]":"24.4","Tissue RNA - breast [nTPM]":"17.9","Tissue RNA - cerebellum [nTPM]":"18.5","Tissue RNA - cerebral cortex [nTPM]":"17.1","Tissue RNA - cervix [nTPM]":"23.6","Tissue RNA - choroid plexus [nTPM]":"13.5","Tissue RNA - colon [nTPM]":"20.4","Tissue RNA - duodenum [nTPM]":"14.6","Tissue RNA - endometrium 1 [nTPM]":"23.5","Tissue RNA - epididymis [nTPM]":"16.2","Tissue RNA - esophagus [nTPM]":"16.1","Tissue RNA - fallopian tube [nTPM]":"23.2","Tissue RNA - gallbladder [nTPM]":"14.4","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"14.6","Tissue RNA - hypothalamus [nTPM]":"15.6","Tissue RNA - kidney [nTPM]":"15.7","Tissue RNA - liver [nTPM]":"10.8","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"22.9","Tissue RNA - medulla oblongata [nTPM]":"15.7","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"32.0","Tissue RNA - pancreas [nTPM]":"19.6","Tissue RNA - parathyroid gland [nTPM]":"17.6","Tissue RNA - pituitary gland [nTPM]":"32.3","Tissue RNA - placenta [nTPM]":"16.6","Tissue RNA - pons [nTPM]":"14.0","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"11.4","Tissue RNA - retina [nTPM]":"16.7","Tissue RNA - salivary gland [nTPM]":"16.3","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"19.5","Tissue RNA - skin 1 [nTPM]":"21.0","Tissue RNA - small intestine [nTPM]":"15.7","Tissue RNA - smooth muscle [nTPM]":"17.3","Tissue RNA - spinal cord [nTPM]":"13.5","Tissue RNA - spleen [nTPM]":"20.1","Tissue RNA - stomach 1 [nTPM]":"18.5","Tissue RNA - testis [nTPM]":"23.9","Tissue RNA - thalamus [nTPM]":"16.6","Tissue RNA - thymus [nTPM]":"29.0","Tissue RNA - thyroid gland [nTPM]":"20.6","Tissue RNA - tongue [nTPM]":"15.7","Tissue RNA - tonsil [nTPM]":"20.9","Tissue RNA - urinary bladder [nTPM]":"18.6","Tissue RNA - vagina [nTPM]":"18.0","Tissue RNA - white matter [nTPM]":"15.6","Cell RNA - A-431 [nTPM]":"57.4","Cell RNA - A549 [nTPM]":"51.4","Cell RNA - AF22 [nTPM]":"54.4","Cell RNA - AN3-CA [nTPM]":"48.2","Cell RNA - ASC diff [nTPM]":"23.6","Cell RNA - ASC TERT1 [nTPM]":"24.6","Cell RNA - BEWO [nTPM]":"27.0","Cell RNA - BJ [nTPM]":"28.4","Cell RNA - BJ hTERT+ [nTPM]":"36.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"46.3","Cell RNA - CACO-2 [nTPM]":"32.0","Cell RNA - CAPAN-2 [nTPM]":"40.4","Cell RNA - Daudi [nTPM]":"44.1","Cell RNA - EFO-21 [nTPM]":"39.1","Cell RNA - fHDF\/TERT166 [nTPM]":"28.9","Cell RNA - GAMG [nTPM]":"39.1","Cell RNA - HaCaT [nTPM]":"30.0","Cell RNA - HAP1 [nTPM]":"33.2","Cell RNA - HBEC3-KT [nTPM]":"36.8","Cell RNA - HBF TERT88 [nTPM]":"24.7","Cell RNA - HDLM-2 [nTPM]":"46.4","Cell RNA - HEK 293 [nTPM]":"33.9","Cell RNA - HEL [nTPM]":"57.5","Cell RNA - HeLa [nTPM]":"49.4","Cell RNA - Hep G2 [nTPM]":"36.1","Cell RNA - HHSteC [nTPM]":"23.2","Cell RNA - HL-60 [nTPM]":"34.5","Cell RNA - HMC-1 [nTPM]":"42.9","Cell RNA - HSkMC [nTPM]":"27.3","Cell RNA - hTCEpi [nTPM]":"24.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"53.5","Cell RNA - hTERT-HME1 [nTPM]":"26.4","Cell RNA - hTERT-RPE1 [nTPM]":"48.8","Cell RNA - HUVEC TERT2 [nTPM]":"37.2","Cell RNA - JURKAT [nTPM]":"49.1","Cell RNA - K-562 [nTPM]":"35.9","Cell RNA - Karpas-707 [nTPM]":"42.5","Cell RNA - LHCN-M2 [nTPM]":"37.3","Cell RNA - MCF7 [nTPM]":"48.9","Cell RNA - MOLT-4 [nTPM]":"57.5","Cell RNA - NB-4 [nTPM]":"52.5","Cell RNA - NTERA-2 [nTPM]":"18.5","Cell RNA - OE19 [nTPM]":"44.2","Cell RNA - PC-3 [nTPM]":"21.3","Cell RNA - REH [nTPM]":"57.0","Cell RNA - RH-30 [nTPM]":"35.4","Cell RNA - RPMI-8226 [nTPM]":"25.8","Cell RNA - RPTEC TERT1 [nTPM]":"34.3","Cell RNA - RT4 [nTPM]":"44.1","Cell RNA - SCLC-21H [nTPM]":"44.5","Cell RNA - SH-SY5Y [nTPM]":"26.5","Cell RNA - SiHa [nTPM]":"41.6","Cell RNA - SK-BR-3 [nTPM]":"35.3","Cell RNA - SK-MEL-30 [nTPM]":"20.7","Cell RNA - SuSa [nTPM]":"26.8","Cell RNA - T-47d [nTPM]":"33.9","Cell RNA - THP-1 [nTPM]":"67.4","Cell RNA - TIME [nTPM]":"23.3","Cell RNA - U-138 MG [nTPM]":"55.7","Cell RNA - U-2 OS [nTPM]":"40.4","Cell RNA - U-2197 [nTPM]":"16.3","Cell RNA - U-251 MG [nTPM]":"39.9","Cell RNA - U-266\/70 [nTPM]":"44.2","Cell RNA - U-266\/84 [nTPM]":"44.2","Cell RNA - U-698 [nTPM]":"32.0","Cell RNA - U-87 MG [nTPM]":"42.8","Cell RNA - U-937 [nTPM]":"28.0","Cell RNA - WM-115 [nTPM]":"58.7","Blood RNA - basophil [nTPM]":"18.6","Blood RNA - classical monocyte [nTPM]":"13.1","Blood RNA - eosinophil [nTPM]":"15.6","Blood RNA - gdT-cell [nTPM]":"10.8","Blood RNA - intermediate monocyte [nTPM]":"11.9","Blood RNA - MAIT T-cell [nTPM]":"12.3","Blood RNA - memory B-cell [nTPM]":"11.7","Blood RNA - memory CD4 T-cell [nTPM]":"13.8","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"11.6","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"11.3","Blood RNA - naive CD8 T-cell [nTPM]":"10.9","Blood RNA - neutrophil [nTPM]":"15.1","Blood RNA - NK-cell [nTPM]":"10.4","Blood RNA - non-classical monocyte [nTPM]":"7.9","Blood RNA - plasmacytoid DC [nTPM]":"9.1","Blood RNA - T-reg [nTPM]":"14.5","Blood RNA - total PBMC [nTPM]":"11.7","Brain RNA - amygdala [nTPM]":"15.3","Brain RNA - basal ganglia [nTPM]":"15.6","Brain RNA - cerebellum [nTPM]":"18.5","Brain RNA - cerebral cortex [nTPM]":"17.1","Brain RNA - hippocampal formation [nTPM]":"14.6","Brain RNA - hypothalamus [nTPM]":"15.6","Brain RNA - medulla oblongata [nTPM]":"15.7","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"14.0","Brain RNA - spinal cord [nTPM]":"13.5","Brain RNA - thalamus [nTPM]":"16.6","Brain RNA - white matter [nTPM]":"15.6","Single Cell Type RNA - Adipocytes [nTPM]":"10.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.8","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"13.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"12.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"14.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.8","Single Cell Type RNA - dendritic cells [nTPM]":"12.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"15.4","Single Cell Type RNA - Early spermatids [nTPM]":"32.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.3","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.7","Single Cell Type RNA - Erythroid cells [nTPM]":"15.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.2","Single Cell Type RNA - Fibroblasts [nTPM]":"13.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.7","Single Cell Type RNA - granulocytes [nTPM]":"19.7","Single Cell Type RNA - Granulosa cells [nTPM]":"22.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"7.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.0","Single Cell Type RNA - Langerhans cells [nTPM]":"10.1","Single Cell Type RNA - Late spermatids [nTPM]":"19.5","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"12.6","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"14.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.6","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.2","Single Cell Type RNA - Paneth cells [nTPM]":"9.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"17.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.7","Single Cell Type RNA - Spermatocytes [nTPM]":"21.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"14.6","Single Cell Type RNA - Theca cells [nTPM]":"16.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.7","Single Cell Type RNA - Urothelial cells [nTPM]":"4.7"},{"Gene":"YARS1","Gene synonym":["tyrRS","YARS","YRS","YTS"],"Ensembl":"ENSG00000134684","Gene description":"Tyrosyl-tRNA synthetase 1","Uniprot":["P54577"],"Chromosome":"1","Position":"32775237-32817380","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","RNA-binding","tRNA-binding"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"17.5","Cytotrophoblasts":"41.8","Extravillous trophoblasts":"48.1","Hofbauer cells":"41.0","Syncytiotrophoblasts":"37.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017936","HPA018950","HPA018954"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017936":"AB_1858916","HPA018950":"AB_1858919","HPA018954":"AB_1858915"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.97e-11"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.57e-4"},"Tissue RNA - adipose tissue [nTPM]":"24.9","Tissue RNA - adrenal gland [nTPM]":"40.3","Tissue RNA - amygdala [nTPM]":"39.9","Tissue RNA - appendix [nTPM]":"35.0","Tissue RNA - basal ganglia [nTPM]":"51.2","Tissue RNA - bone marrow [nTPM]":"19.9","Tissue RNA - breast [nTPM]":"21.3","Tissue RNA - cerebellum [nTPM]":"38.1","Tissue RNA - cerebral cortex [nTPM]":"60.4","Tissue RNA - cervix [nTPM]":"20.5","Tissue RNA - choroid plexus [nTPM]":"30.1","Tissue RNA - colon [nTPM]":"27.5","Tissue RNA - duodenum [nTPM]":"26.0","Tissue RNA - endometrium 1 [nTPM]":"16.9","Tissue RNA - epididymis [nTPM]":"25.0","Tissue RNA - esophagus [nTPM]":"34.4","Tissue RNA - fallopian tube [nTPM]":"21.6","Tissue RNA - gallbladder [nTPM]":"15.3","Tissue RNA - heart muscle [nTPM]":"22.4","Tissue RNA - hippocampal formation [nTPM]":"42.1","Tissue RNA - hypothalamus [nTPM]":"46.6","Tissue RNA - kidney [nTPM]":"20.6","Tissue RNA - liver [nTPM]":"47.7","Tissue RNA - lung [nTPM]":"27.8","Tissue RNA - lymph node [nTPM]":"38.2","Tissue RNA - medulla oblongata [nTPM]":"37.5","Tissue RNA - midbrain [nTPM]":"38.4","Tissue RNA - ovary [nTPM]":"15.1","Tissue RNA - pancreas [nTPM]":"85.6","Tissue RNA - parathyroid gland [nTPM]":"34.1","Tissue RNA - pituitary gland [nTPM]":"14.8","Tissue RNA - placenta [nTPM]":"26.2","Tissue RNA - pons [nTPM]":"42.3","Tissue RNA - prostate [nTPM]":"18.8","Tissue RNA - rectum [nTPM]":"32.4","Tissue RNA - retina [nTPM]":"38.0","Tissue RNA - salivary gland [nTPM]":"29.6","Tissue RNA - seminal vesicle [nTPM]":"29.0","Tissue RNA - skeletal muscle [nTPM]":"31.9","Tissue RNA - skin 1 [nTPM]":"26.0","Tissue RNA - small intestine [nTPM]":"21.6","Tissue RNA - smooth muscle [nTPM]":"35.4","Tissue RNA - spinal cord [nTPM]":"38.5","Tissue RNA - spleen [nTPM]":"22.0","Tissue RNA - stomach 1 [nTPM]":"40.8","Tissue RNA - testis [nTPM]":"31.2","Tissue RNA - thalamus [nTPM]":"44.2","Tissue RNA - thymus [nTPM]":"34.6","Tissue RNA - thyroid gland [nTPM]":"42.3","Tissue RNA - tongue [nTPM]":"36.6","Tissue RNA - tonsil [nTPM]":"50.0","Tissue RNA - urinary bladder [nTPM]":"34.6","Tissue RNA - vagina [nTPM]":"14.0","Tissue RNA - white matter [nTPM]":"49.6","Cell RNA - A-431 [nTPM]":"157.1","Cell RNA - A549 [nTPM]":"92.1","Cell RNA - AF22 [nTPM]":"86.1","Cell RNA - AN3-CA [nTPM]":"194.5","Cell RNA - ASC diff [nTPM]":"111.2","Cell RNA - ASC TERT1 [nTPM]":"117.7","Cell RNA - BEWO [nTPM]":"91.7","Cell RNA - BJ [nTPM]":"151.0","Cell RNA - BJ hTERT+ [nTPM]":"136.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"133.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"165.0","Cell RNA - CACO-2 [nTPM]":"116.6","Cell RNA - CAPAN-2 [nTPM]":"103.0","Cell RNA - Daudi [nTPM]":"287.5","Cell RNA - EFO-21 [nTPM]":"63.1","Cell RNA - fHDF\/TERT166 [nTPM]":"173.2","Cell RNA - GAMG [nTPM]":"112.7","Cell RNA - HaCaT [nTPM]":"90.8","Cell RNA - HAP1 [nTPM]":"269.0","Cell RNA - HBEC3-KT [nTPM]":"204.4","Cell RNA - HBF TERT88 [nTPM]":"198.9","Cell RNA - HDLM-2 [nTPM]":"122.6","Cell RNA - HEK 293 [nTPM]":"113.9","Cell RNA - HEL [nTPM]":"254.2","Cell RNA - HeLa [nTPM]":"117.2","Cell RNA - Hep G2 [nTPM]":"114.2","Cell RNA - HHSteC [nTPM]":"383.4","Cell RNA - HL-60 [nTPM]":"202.9","Cell RNA - HMC-1 [nTPM]":"147.3","Cell RNA - HSkMC [nTPM]":"129.0","Cell RNA - hTCEpi [nTPM]":"252.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"212.7","Cell RNA - hTERT-HME1 [nTPM]":"544.2","Cell RNA - hTERT-RPE1 [nTPM]":"98.3","Cell RNA - HUVEC TERT2 [nTPM]":"140.9","Cell RNA - JURKAT [nTPM]":"245.8","Cell RNA - K-562 [nTPM]":"291.8","Cell RNA - Karpas-707 [nTPM]":"268.7","Cell RNA - LHCN-M2 [nTPM]":"117.8","Cell RNA - MCF7 [nTPM]":"107.8","Cell RNA - MOLT-4 [nTPM]":"233.0","Cell RNA - NB-4 [nTPM]":"159.3","Cell RNA - NTERA-2 [nTPM]":"149.1","Cell RNA - OE19 [nTPM]":"185.3","Cell RNA - PC-3 [nTPM]":"134.5","Cell RNA - REH [nTPM]":"198.3","Cell RNA - RH-30 [nTPM]":"75.2","Cell RNA - RPMI-8226 [nTPM]":"234.9","Cell RNA - RPTEC TERT1 [nTPM]":"109.8","Cell RNA - RT4 [nTPM]":"76.5","Cell RNA - SCLC-21H [nTPM]":"149.5","Cell RNA - SH-SY5Y [nTPM]":"94.2","Cell RNA - SiHa [nTPM]":"89.0","Cell RNA - SK-BR-3 [nTPM]":"102.7","Cell RNA - SK-MEL-30 [nTPM]":"300.8","Cell RNA - SuSa [nTPM]":"99.2","Cell RNA - T-47d [nTPM]":"95.2","Cell RNA - THP-1 [nTPM]":"247.5","Cell RNA - TIME [nTPM]":"103.6","Cell RNA - U-138 MG [nTPM]":"73.6","Cell RNA - U-2 OS [nTPM]":"135.7","Cell RNA - U-2197 [nTPM]":"152.1","Cell RNA - U-251 MG [nTPM]":"135.7","Cell RNA - U-266\/70 [nTPM]":"242.8","Cell RNA - U-266\/84 [nTPM]":"265.2","Cell RNA - U-698 [nTPM]":"255.7","Cell RNA - U-87 MG [nTPM]":"184.8","Cell RNA - U-937 [nTPM]":"297.7","Cell RNA - WM-115 [nTPM]":"203.6","Blood RNA - basophil [nTPM]":"56.1","Blood RNA - classical monocyte [nTPM]":"33.3","Blood RNA - eosinophil [nTPM]":"17.8","Blood RNA - gdT-cell [nTPM]":"59.0","Blood RNA - intermediate monocyte [nTPM]":"35.2","Blood RNA - MAIT T-cell [nTPM]":"58.4","Blood RNA - memory B-cell [nTPM]":"23.8","Blood RNA - memory CD4 T-cell [nTPM]":"35.4","Blood RNA - memory CD8 T-cell [nTPM]":"55.1","Blood RNA - myeloid DC [nTPM]":"45.8","Blood RNA - naive B-cell [nTPM]":"20.3","Blood RNA - naive CD4 T-cell [nTPM]":"25.2","Blood RNA - naive CD8 T-cell [nTPM]":"39.0","Blood RNA - neutrophil [nTPM]":"6.9","Blood RNA - NK-cell [nTPM]":"98.1","Blood RNA - non-classical monocyte [nTPM]":"35.0","Blood RNA - plasmacytoid DC [nTPM]":"26.9","Blood RNA - T-reg [nTPM]":"40.9","Blood RNA - total PBMC [nTPM]":"51.5","Brain RNA - amygdala [nTPM]":"39.9","Brain RNA - basal ganglia [nTPM]":"51.2","Brain RNA - cerebellum [nTPM]":"38.1","Brain RNA - cerebral cortex [nTPM]":"60.4","Brain RNA - hippocampal formation [nTPM]":"42.1","Brain RNA - hypothalamus [nTPM]":"46.6","Brain RNA - medulla oblongata [nTPM]":"37.5","Brain RNA - midbrain [nTPM]":"38.4","Brain RNA - pons [nTPM]":"42.3","Brain RNA - spinal cord [nTPM]":"38.5","Brain RNA - thalamus [nTPM]":"44.2","Brain RNA - white matter [nTPM]":"49.6","Single Cell Type RNA - Adipocytes [nTPM]":"7.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.8","Single Cell Type RNA - dendritic cells [nTPM]":"11.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.6","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"YEATS2","Gene synonym":["FLJ10201","FLJ12841","FLJ13308","KIAA1197"],"Ensembl":"ENSG00000163872","Gene description":"YEATS domain containing 2","Uniprot":["Q9ULM3"],"Chromosome":"3","Position":"183697797-183812624","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"95.6","Inhibitory neurons":"62.1","Oligodendrocyte precursor cells":"71.9","Oligodendrocytes":"80.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045891"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA045891":"AB_10961271"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.82e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.90e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"4.8","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"8.9","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"14.5","Tissue RNA - breast [nTPM]":"7.9","Tissue RNA - cerebellum [nTPM]":"8.1","Tissue RNA - cerebral cortex [nTPM]":"8.8","Tissue RNA - cervix [nTPM]":"8.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"9.1","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"6.4","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"6.1","Tissue RNA - liver [nTPM]":"3.4","Tissue RNA - lung [nTPM]":"10.0","Tissue RNA - lymph node [nTPM]":"12.9","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"15.1","Tissue RNA - pancreas [nTPM]":"5.4","Tissue RNA - parathyroid gland [nTPM]":"9.9","Tissue RNA - pituitary gland [nTPM]":"8.6","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"15.6","Tissue RNA - salivary gland [nTPM]":"8.0","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"8.5","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"11.9","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"8.9","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"8.0","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"16.9","Tissue RNA - thyroid gland [nTPM]":"9.7","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"11.8","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"7.0","Cell RNA - A-431 [nTPM]":"38.1","Cell RNA - A549 [nTPM]":"11.3","Cell RNA - AF22 [nTPM]":"32.4","Cell RNA - AN3-CA [nTPM]":"14.5","Cell RNA - ASC diff [nTPM]":"15.5","Cell RNA - ASC TERT1 [nTPM]":"22.8","Cell RNA - BEWO [nTPM]":"35.8","Cell RNA - BJ [nTPM]":"22.1","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.5","Cell RNA - CACO-2 [nTPM]":"27.8","Cell RNA - CAPAN-2 [nTPM]":"13.3","Cell RNA - Daudi [nTPM]":"34.7","Cell RNA - EFO-21 [nTPM]":"39.8","Cell RNA - fHDF\/TERT166 [nTPM]":"19.5","Cell RNA - GAMG [nTPM]":"49.9","Cell RNA - HaCaT [nTPM]":"23.9","Cell RNA - HAP1 [nTPM]":"31.8","Cell RNA - HBEC3-KT [nTPM]":"21.2","Cell RNA - HBF TERT88 [nTPM]":"32.7","Cell RNA - HDLM-2 [nTPM]":"28.5","Cell RNA - HEK 293 [nTPM]":"18.8","Cell RNA - HEL [nTPM]":"35.0","Cell RNA - HeLa [nTPM]":"12.2","Cell RNA - Hep G2 [nTPM]":"13.7","Cell RNA - HHSteC [nTPM]":"23.9","Cell RNA - HL-60 [nTPM]":"26.3","Cell RNA - HMC-1 [nTPM]":"19.4","Cell RNA - HSkMC [nTPM]":"15.6","Cell RNA - hTCEpi [nTPM]":"16.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.1","Cell RNA - hTERT-HME1 [nTPM]":"27.8","Cell RNA - hTERT-RPE1 [nTPM]":"32.1","Cell RNA - HUVEC TERT2 [nTPM]":"33.1","Cell RNA - JURKAT [nTPM]":"35.2","Cell RNA - K-562 [nTPM]":"14.0","Cell RNA - Karpas-707 [nTPM]":"28.3","Cell RNA - LHCN-M2 [nTPM]":"24.5","Cell RNA - MCF7 [nTPM]":"10.2","Cell RNA - MOLT-4 [nTPM]":"38.3","Cell RNA - NB-4 [nTPM]":"20.2","Cell RNA - NTERA-2 [nTPM]":"29.3","Cell RNA - OE19 [nTPM]":"13.8","Cell RNA - PC-3 [nTPM]":"22.0","Cell RNA - REH [nTPM]":"53.5","Cell RNA - RH-30 [nTPM]":"30.5","Cell RNA - RPMI-8226 [nTPM]":"42.0","Cell RNA - RPTEC TERT1 [nTPM]":"12.9","Cell RNA - RT4 [nTPM]":"16.6","Cell RNA - SCLC-21H [nTPM]":"31.3","Cell RNA - SH-SY5Y [nTPM]":"22.3","Cell RNA - SiHa [nTPM]":"16.4","Cell RNA - SK-BR-3 [nTPM]":"55.4","Cell RNA - SK-MEL-30 [nTPM]":"29.2","Cell RNA - SuSa [nTPM]":"27.1","Cell RNA - T-47d [nTPM]":"27.5","Cell RNA - THP-1 [nTPM]":"17.8","Cell RNA - TIME [nTPM]":"28.2","Cell RNA - U-138 MG [nTPM]":"29.5","Cell RNA - U-2 OS [nTPM]":"21.3","Cell RNA - U-2197 [nTPM]":"15.1","Cell RNA - U-251 MG [nTPM]":"25.0","Cell RNA - U-266\/70 [nTPM]":"26.9","Cell RNA - U-266\/84 [nTPM]":"22.6","Cell RNA - U-698 [nTPM]":"57.6","Cell RNA - U-87 MG [nTPM]":"22.9","Cell RNA - U-937 [nTPM]":"25.8","Cell RNA - WM-115 [nTPM]":"21.3","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"4.6","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"8.5","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"7.1","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"8.1","Brain RNA - cerebral cortex [nTPM]":"8.8","Brain RNA - hippocampal formation [nTPM]":"6.4","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"7.0","Single Cell Type RNA - Adipocytes [nTPM]":"13.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.3","Single Cell Type RNA - Astrocytes [nTPM]":"41.4","Single Cell Type RNA - B-cells [nTPM]":"7.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"19.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"5.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - dendritic cells [nTPM]":"7.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.3","Single Cell Type RNA - Endothelial cells [nTPM]":"15.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.5","Single Cell Type RNA - Erythroid cells [nTPM]":"6.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"95.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.7","Single Cell Type RNA - Fibroblasts [nTPM]":"9.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.8","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"42.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"3.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"62.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.7","Single Cell Type RNA - Langerhans cells [nTPM]":"6.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"10.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"6.6","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"71.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"80.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"8.8","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.8"},{"Gene":"YME1L1","Gene synonym":["YME1L"],"Ensembl":"ENSG00000136758","Gene description":"YME1 like 1 ATPase","Uniprot":["Q96TA2"],"Chromosome":"10","Position":"27110111-27155266","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066953"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA066953":"AB_2685753"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.25e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.8","Tissue RNA - adrenal gland [nTPM]":"52.6","Tissue RNA - amygdala [nTPM]":"17.7","Tissue RNA - appendix [nTPM]":"51.7","Tissue RNA - basal ganglia [nTPM]":"18.4","Tissue RNA - bone marrow [nTPM]":"95.1","Tissue RNA - breast [nTPM]":"47.5","Tissue RNA - cerebellum [nTPM]":"23.3","Tissue RNA - cerebral cortex [nTPM]":"21.7","Tissue RNA - cervix [nTPM]":"52.4","Tissue RNA - choroid plexus [nTPM]":"36.4","Tissue RNA - colon [nTPM]":"52.2","Tissue RNA - duodenum [nTPM]":"46.0","Tissue RNA - endometrium 1 [nTPM]":"50.3","Tissue RNA - epididymis [nTPM]":"53.3","Tissue RNA - esophagus [nTPM]":"59.1","Tissue RNA - fallopian tube [nTPM]":"43.7","Tissue RNA - gallbladder [nTPM]":"46.0","Tissue RNA - heart muscle [nTPM]":"61.4","Tissue RNA - hippocampal formation [nTPM]":"17.8","Tissue RNA - hypothalamus [nTPM]":"22.7","Tissue RNA - kidney [nTPM]":"54.0","Tissue RNA - liver [nTPM]":"65.5","Tissue RNA - lung [nTPM]":"39.8","Tissue RNA - lymph node [nTPM]":"56.6","Tissue RNA - medulla oblongata [nTPM]":"18.2","Tissue RNA - midbrain [nTPM]":"22.1","Tissue RNA - ovary [nTPM]":"50.8","Tissue RNA - pancreas [nTPM]":"52.0","Tissue RNA - parathyroid gland [nTPM]":"54.5","Tissue RNA - pituitary gland [nTPM]":"33.3","Tissue RNA - placenta [nTPM]":"61.1","Tissue RNA - pons [nTPM]":"19.9","Tissue RNA - prostate [nTPM]":"48.4","Tissue RNA - rectum [nTPM]":"52.4","Tissue RNA - retina [nTPM]":"42.0","Tissue RNA - salivary gland [nTPM]":"44.7","Tissue RNA - seminal vesicle [nTPM]":"44.5","Tissue RNA - skeletal muscle [nTPM]":"111.4","Tissue RNA - skin 1 [nTPM]":"40.1","Tissue RNA - small intestine [nTPM]":"46.3","Tissue RNA - smooth muscle [nTPM]":"49.2","Tissue RNA - spinal cord [nTPM]":"16.6","Tissue RNA - spleen [nTPM]":"46.4","Tissue RNA - stomach 1 [nTPM]":"48.8","Tissue RNA - testis [nTPM]":"51.2","Tissue RNA - thalamus [nTPM]":"19.7","Tissue RNA - thymus [nTPM]":"65.9","Tissue RNA - thyroid gland [nTPM]":"62.2","Tissue RNA - tongue [nTPM]":"97.7","Tissue RNA - tonsil [nTPM]":"62.5","Tissue RNA - urinary bladder [nTPM]":"56.8","Tissue RNA - vagina [nTPM]":"35.0","Tissue RNA - white matter [nTPM]":"24.4","Cell RNA - A-431 [nTPM]":"146.6","Cell RNA - A549 [nTPM]":"105.3","Cell RNA - AF22 [nTPM]":"125.5","Cell RNA - AN3-CA [nTPM]":"62.0","Cell RNA - ASC diff [nTPM]":"118.3","Cell RNA - ASC TERT1 [nTPM]":"123.9","Cell RNA - BEWO [nTPM]":"100.7","Cell RNA - BJ [nTPM]":"143.3","Cell RNA - BJ hTERT+ [nTPM]":"79.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"139.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"157.6","Cell RNA - CACO-2 [nTPM]":"143.3","Cell RNA - CAPAN-2 [nTPM]":"171.9","Cell RNA - Daudi [nTPM]":"152.1","Cell RNA - EFO-21 [nTPM]":"90.8","Cell RNA - fHDF\/TERT166 [nTPM]":"154.8","Cell RNA - GAMG [nTPM]":"100.5","Cell RNA - HaCaT [nTPM]":"135.6","Cell RNA - HAP1 [nTPM]":"152.8","Cell RNA - HBEC3-KT [nTPM]":"122.6","Cell RNA - HBF TERT88 [nTPM]":"152.9","Cell RNA - HDLM-2 [nTPM]":"143.4","Cell RNA - HEK 293 [nTPM]":"89.0","Cell RNA - HEL [nTPM]":"144.4","Cell RNA - HeLa [nTPM]":"91.0","Cell RNA - Hep G2 [nTPM]":"98.3","Cell RNA - HHSteC [nTPM]":"124.6","Cell RNA - HL-60 [nTPM]":"100.4","Cell RNA - HMC-1 [nTPM]":"114.5","Cell RNA - HSkMC [nTPM]":"104.7","Cell RNA - hTCEpi [nTPM]":"143.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"123.4","Cell RNA - hTERT-HME1 [nTPM]":"121.6","Cell RNA - hTERT-RPE1 [nTPM]":"122.5","Cell RNA - HUVEC TERT2 [nTPM]":"146.7","Cell RNA - JURKAT [nTPM]":"138.8","Cell RNA - K-562 [nTPM]":"173.8","Cell RNA - Karpas-707 [nTPM]":"150.5","Cell RNA - LHCN-M2 [nTPM]":"154.4","Cell RNA - MCF7 [nTPM]":"95.1","Cell RNA - MOLT-4 [nTPM]":"189.1","Cell RNA - NB-4 [nTPM]":"53.7","Cell RNA - NTERA-2 [nTPM]":"97.4","Cell RNA - OE19 [nTPM]":"119.3","Cell RNA - PC-3 [nTPM]":"49.4","Cell RNA - REH [nTPM]":"160.4","Cell RNA - RH-30 [nTPM]":"199.7","Cell RNA - RPMI-8226 [nTPM]":"143.0","Cell RNA - RPTEC TERT1 [nTPM]":"107.7","Cell RNA - RT4 [nTPM]":"68.2","Cell RNA - SCLC-21H [nTPM]":"95.6","Cell RNA - SH-SY5Y [nTPM]":"121.9","Cell RNA - SiHa [nTPM]":"138.4","Cell RNA - SK-BR-3 [nTPM]":"105.2","Cell RNA - SK-MEL-30 [nTPM]":"138.9","Cell RNA - SuSa [nTPM]":"102.8","Cell RNA - T-47d [nTPM]":"101.5","Cell RNA - THP-1 [nTPM]":"115.1","Cell RNA - TIME [nTPM]":"146.9","Cell RNA - U-138 MG [nTPM]":"83.4","Cell RNA - U-2 OS [nTPM]":"117.3","Cell RNA - U-2197 [nTPM]":"140.8","Cell RNA - U-251 MG [nTPM]":"126.7","Cell RNA - U-266\/70 [nTPM]":"75.1","Cell RNA - U-266\/84 [nTPM]":"121.9","Cell RNA - U-698 [nTPM]":"196.1","Cell RNA - U-87 MG [nTPM]":"119.4","Cell RNA - U-937 [nTPM]":"178.8","Cell RNA - WM-115 [nTPM]":"65.8","Blood RNA - basophil [nTPM]":"195.0","Blood RNA - classical monocyte [nTPM]":"146.4","Blood RNA - eosinophil [nTPM]":"165.4","Blood RNA - gdT-cell [nTPM]":"147.5","Blood RNA - intermediate monocyte [nTPM]":"128.5","Blood RNA - MAIT T-cell [nTPM]":"149.4","Blood RNA - memory B-cell [nTPM]":"143.0","Blood RNA - memory CD4 T-cell [nTPM]":"142.4","Blood RNA - memory CD8 T-cell [nTPM]":"138.8","Blood RNA - myeloid DC [nTPM]":"121.9","Blood RNA - naive B-cell [nTPM]":"149.7","Blood RNA - naive CD4 T-cell [nTPM]":"129.3","Blood RNA - naive CD8 T-cell [nTPM]":"136.8","Blood RNA - neutrophil [nTPM]":"204.0","Blood RNA - NK-cell [nTPM]":"135.6","Blood RNA - non-classical monocyte [nTPM]":"143.1","Blood RNA - plasmacytoid DC [nTPM]":"222.6","Blood RNA - T-reg [nTPM]":"156.7","Blood RNA - total PBMC [nTPM]":"155.5","Brain RNA - amygdala [nTPM]":"17.7","Brain RNA - basal ganglia [nTPM]":"18.4","Brain RNA - cerebellum [nTPM]":"23.3","Brain RNA - cerebral cortex [nTPM]":"21.7","Brain RNA - hippocampal formation [nTPM]":"17.8","Brain RNA - hypothalamus [nTPM]":"22.7","Brain RNA - medulla oblongata [nTPM]":"18.2","Brain RNA - midbrain [nTPM]":"22.1","Brain RNA - pons [nTPM]":"19.9","Brain RNA - spinal cord [nTPM]":"16.6","Brain RNA - thalamus [nTPM]":"19.7","Brain RNA - white matter [nTPM]":"24.4","Single Cell Type RNA - Adipocytes [nTPM]":"105.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"81.8","Single Cell Type RNA - Astrocytes [nTPM]":"40.5","Single Cell Type RNA - B-cells [nTPM]":"108.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"70.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"96.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"55.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"92.2","Single Cell Type RNA - Bipolar cells [nTPM]":"53.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"76.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"90.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"103.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"66.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"83.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"61.2","Single Cell Type RNA - dendritic cells [nTPM]":"121.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"179.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"52.2","Single Cell Type RNA - Early spermatids [nTPM]":"62.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"141.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"152.5","Single Cell Type RNA - Endothelial cells [nTPM]":"86.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"50.3","Single Cell Type RNA - Erythroid cells [nTPM]":"63.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"67.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"48.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"74.4","Single Cell Type RNA - Fibroblasts [nTPM]":"101.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"136.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"224.3","Single Cell Type RNA - granulocytes [nTPM]":"110.8","Single Cell Type RNA - Granulosa cells [nTPM]":"75.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"58.5","Single Cell Type RNA - Hepatocytes [nTPM]":"70.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"73.2","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"68.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"121.2","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"98.9","Single Cell Type RNA - Langerhans cells [nTPM]":"133.2","Single Cell Type RNA - Late spermatids [nTPM]":"27.0","Single Cell Type RNA - Leydig cells [nTPM]":"57.8","Single Cell Type RNA - Macrophages [nTPM]":"125.4","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"41.2","Single Cell Type RNA - monocytes [nTPM]":"63.7","Single Cell Type RNA - Muller glia cells [nTPM]":"63.8","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"75.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"66.8","Single Cell Type RNA - Paneth cells [nTPM]":"109.3","Single Cell Type RNA - Peritubular cells [nTPM]":"43.2","Single Cell Type RNA - Plasma cells [nTPM]":"93.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"83.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"156.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"47.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"70.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.7","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"156.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.5","Single Cell Type RNA - Spermatocytes [nTPM]":"143.4","Single Cell Type RNA - Spermatogonia [nTPM]":"57.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"92.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"64.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"94.8","Single Cell Type RNA - T-cells [nTPM]":"122.1","Single Cell Type RNA - Theca cells [nTPM]":"102.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"104.4","Single Cell Type RNA - Urothelial cells [nTPM]":"75.0"},{"Gene":"YWHAG","Gene synonym":["14-3-3\u00c3\u017d\u00c2\u00b3","14-3-3GAMMA","PPP1R170"],"Ensembl":"ENSG00000170027","Gene description":"Tyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein gamma","Uniprot":["P61981"],"Chromosome":"7","Position":"76326799-76358991","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"337.4","skeletal muscle":"349.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"408.8","Suprabasal keratinocytes":"425.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013274","CAB018389","HPA026918"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"66000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB013274":null,"CAB018389":"AB_2217962","HPA026918":"AB_10610566"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.53e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.34e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.44e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"188.1","Tissue RNA - adrenal gland [nTPM]":"99.2","Tissue RNA - amygdala [nTPM]":"165.6","Tissue RNA - appendix [nTPM]":"60.6","Tissue RNA - basal ganglia [nTPM]":"185.3","Tissue RNA - bone marrow [nTPM]":"27.3","Tissue RNA - breast [nTPM]":"61.0","Tissue RNA - cerebellum [nTPM]":"80.2","Tissue RNA - cerebral cortex [nTPM]":"337.4","Tissue RNA - cervix [nTPM]":"41.1","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"48.4","Tissue RNA - duodenum [nTPM]":"47.8","Tissue RNA - endometrium 1 [nTPM]":"50.9","Tissue RNA - epididymis [nTPM]":"20.8","Tissue RNA - esophagus [nTPM]":"64.5","Tissue RNA - fallopian tube [nTPM]":"37.9","Tissue RNA - gallbladder [nTPM]":"54.5","Tissue RNA - heart muscle [nTPM]":"111.4","Tissue RNA - hippocampal formation [nTPM]":"206.5","Tissue RNA - hypothalamus [nTPM]":"206.1","Tissue RNA - kidney [nTPM]":"50.8","Tissue RNA - liver [nTPM]":"72.4","Tissue RNA - lung [nTPM]":"47.1","Tissue RNA - lymph node [nTPM]":"43.2","Tissue RNA - medulla oblongata [nTPM]":"204.5","Tissue RNA - midbrain [nTPM]":"120.7","Tissue RNA - ovary [nTPM]":"40.7","Tissue RNA - pancreas [nTPM]":"59.7","Tissue RNA - parathyroid gland [nTPM]":"50.1","Tissue RNA - pituitary gland [nTPM]":"32.6","Tissue RNA - placenta [nTPM]":"55.4","Tissue RNA - pons [nTPM]":"192.9","Tissue RNA - prostate [nTPM]":"46.1","Tissue RNA - rectum [nTPM]":"44.0","Tissue RNA - retina [nTPM]":"87.2","Tissue RNA - salivary gland [nTPM]":"39.9","Tissue RNA - seminal vesicle [nTPM]":"40.0","Tissue RNA - skeletal muscle [nTPM]":"349.8","Tissue RNA - skin 1 [nTPM]":"43.7","Tissue RNA - small intestine [nTPM]":"41.6","Tissue RNA - smooth muscle [nTPM]":"66.4","Tissue RNA - spinal cord [nTPM]":"81.5","Tissue RNA - spleen [nTPM]":"44.2","Tissue RNA - stomach 1 [nTPM]":"38.2","Tissue RNA - testis [nTPM]":"28.9","Tissue RNA - thalamus [nTPM]":"135.1","Tissue RNA - thymus [nTPM]":"40.2","Tissue RNA - thyroid gland [nTPM]":"29.7","Tissue RNA - tongue [nTPM]":"238.4","Tissue RNA - tonsil [nTPM]":"48.6","Tissue RNA - urinary bladder [nTPM]":"78.8","Tissue RNA - vagina [nTPM]":"46.3","Tissue RNA - white matter [nTPM]":"199.1","Cell RNA - A-431 [nTPM]":"189.0","Cell RNA - A549 [nTPM]":"231.9","Cell RNA - AF22 [nTPM]":"200.5","Cell RNA - AN3-CA [nTPM]":"256.7","Cell RNA - ASC diff [nTPM]":"200.5","Cell RNA - ASC TERT1 [nTPM]":"114.9","Cell RNA - BEWO [nTPM]":"90.5","Cell RNA - BJ [nTPM]":"213.3","Cell RNA - BJ hTERT+ [nTPM]":"105.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"129.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"139.5","Cell RNA - CACO-2 [nTPM]":"147.0","Cell RNA - CAPAN-2 [nTPM]":"196.7","Cell RNA - Daudi [nTPM]":"263.5","Cell RNA - EFO-21 [nTPM]":"71.7","Cell RNA - fHDF\/TERT166 [nTPM]":"190.8","Cell RNA - GAMG [nTPM]":"215.2","Cell RNA - HaCaT [nTPM]":"171.6","Cell RNA - HAP1 [nTPM]":"254.3","Cell RNA - HBEC3-KT [nTPM]":"235.8","Cell RNA - HBF TERT88 [nTPM]":"180.5","Cell RNA - HDLM-2 [nTPM]":"179.9","Cell RNA - HEK 293 [nTPM]":"110.9","Cell RNA - HEL [nTPM]":"250.2","Cell RNA - HeLa [nTPM]":"150.0","Cell RNA - Hep G2 [nTPM]":"164.5","Cell RNA - HHSteC [nTPM]":"182.6","Cell RNA - HL-60 [nTPM]":"309.0","Cell RNA - HMC-1 [nTPM]":"234.0","Cell RNA - HSkMC [nTPM]":"127.1","Cell RNA - hTCEpi [nTPM]":"221.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"151.5","Cell RNA - hTERT-HME1 [nTPM]":"310.8","Cell RNA - hTERT-RPE1 [nTPM]":"137.3","Cell RNA - HUVEC TERT2 [nTPM]":"208.9","Cell RNA - JURKAT [nTPM]":"140.2","Cell RNA - K-562 [nTPM]":"349.9","Cell RNA - Karpas-707 [nTPM]":"289.0","Cell RNA - LHCN-M2 [nTPM]":"195.8","Cell RNA - MCF7 [nTPM]":"177.6","Cell RNA - MOLT-4 [nTPM]":"222.3","Cell RNA - NB-4 [nTPM]":"227.1","Cell RNA - NTERA-2 [nTPM]":"223.0","Cell RNA - OE19 [nTPM]":"150.7","Cell RNA - PC-3 [nTPM]":"160.4","Cell RNA - REH [nTPM]":"256.3","Cell RNA - RH-30 [nTPM]":"203.0","Cell RNA - RPMI-8226 [nTPM]":"291.7","Cell RNA - RPTEC TERT1 [nTPM]":"204.5","Cell RNA - RT4 [nTPM]":"126.3","Cell RNA - SCLC-21H [nTPM]":"107.0","Cell RNA - SH-SY5Y [nTPM]":"297.1","Cell RNA - SiHa [nTPM]":"236.7","Cell RNA - SK-BR-3 [nTPM]":"299.2","Cell RNA - SK-MEL-30 [nTPM]":"156.0","Cell RNA - SuSa [nTPM]":"256.9","Cell RNA - T-47d [nTPM]":"208.5","Cell RNA - THP-1 [nTPM]":"184.2","Cell RNA - TIME [nTPM]":"222.6","Cell RNA - U-138 MG [nTPM]":"250.7","Cell RNA - U-2 OS [nTPM]":"145.7","Cell RNA - U-2197 [nTPM]":"225.4","Cell RNA - U-251 MG [nTPM]":"290.1","Cell RNA - U-266\/70 [nTPM]":"95.1","Cell RNA - U-266\/84 [nTPM]":"191.6","Cell RNA - U-698 [nTPM]":"399.5","Cell RNA - U-87 MG [nTPM]":"225.5","Cell RNA - U-937 [nTPM]":"285.3","Cell RNA - WM-115 [nTPM]":"273.8","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"2.6","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"165.6","Brain RNA - basal ganglia [nTPM]":"185.3","Brain RNA - cerebellum [nTPM]":"80.2","Brain RNA - cerebral cortex [nTPM]":"337.4","Brain RNA - hippocampal formation [nTPM]":"206.5","Brain RNA - hypothalamus [nTPM]":"206.1","Brain RNA - medulla oblongata [nTPM]":"204.5","Brain RNA - midbrain [nTPM]":"120.7","Brain RNA - pons [nTPM]":"192.9","Brain RNA - spinal cord [nTPM]":"81.5","Brain RNA - thalamus [nTPM]":"135.1","Brain RNA - white matter [nTPM]":"199.1","Single Cell Type RNA - Adipocytes [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.4","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"51.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"408.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"128.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"87.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"126.9","Single Cell Type RNA - Bipolar cells [nTPM]":"102.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"107.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"70.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"234.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"55.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.5","Single Cell Type RNA - dendritic cells [nTPM]":"39.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Ductal cells [nTPM]":"52.4","Single Cell Type RNA - Early spermatids [nTPM]":"91.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"96.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"82.9","Single Cell Type RNA - Endothelial cells [nTPM]":"92.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"85.4","Single Cell Type RNA - Erythroid cells [nTPM]":"72.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"99.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"84.1","Single Cell Type RNA - Fibroblasts [nTPM]":"97.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"61.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"127.9","Single Cell Type RNA - granulocytes [nTPM]":"67.3","Single Cell Type RNA - Granulosa cells [nTPM]":"38.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"50.0","Single Cell Type RNA - Hepatocytes [nTPM]":"93.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"83.5","Single Cell Type RNA - Horizontal cells [nTPM]":"124.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"78.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.7","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"90.3","Single Cell Type RNA - Langerhans cells [nTPM]":"229.0","Single Cell Type RNA - Late spermatids [nTPM]":"25.2","Single Cell Type RNA - Leydig cells [nTPM]":"46.3","Single Cell Type RNA - Macrophages [nTPM]":"87.8","Single Cell Type RNA - Melanocytes [nTPM]":"94.3","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"64.2","Single Cell Type RNA - Muller glia cells [nTPM]":"27.1","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"57.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"71.1","Single Cell Type RNA - Paneth cells [nTPM]":"29.9","Single Cell Type RNA - Peritubular cells [nTPM]":"43.2","Single Cell Type RNA - Plasma cells [nTPM]":"56.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"129.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"61.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"47.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.3","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"92.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"91.5","Single Cell Type RNA - Spermatocytes [nTPM]":"13.4","Single Cell Type RNA - Spermatogonia [nTPM]":"19.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"160.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"425.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"67.2","Single Cell Type RNA - T-cells [nTPM]":"41.5","Single Cell Type RNA - Theca cells [nTPM]":"46.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"45.1","Single Cell Type RNA - Urothelial cells [nTPM]":"177.1"},{"Gene":"ZEB1","Gene synonym":["AREB6","BZP","FECD6","NIL-2-A","PPCD3","TCF8","ZEB","Zfhep","Zfhx1a"],"Ensembl":"ENSG00000148516","Gene description":"Zinc finger E-box binding homeobox 1","Uniprot":["P37275"],"Chromosome":"10","Position":"31318495-31529814","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"287.8","Excitatory neurons":"276.1","Inhibitory neurons":"261.9","Microglial cells":"479.7","Oligodendrocyte precursor cells":"968.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"15.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"113.1","TIME":"87.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027524","CAB058686","CAB079943"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB058686":"AB_2665569","CAB079943":null,"HPA027524":"AB_1844977"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"26.6","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"16.4","Tissue RNA - appendix [nTPM]":"12.9","Tissue RNA - basal ganglia [nTPM]":"16.2","Tissue RNA - bone marrow [nTPM]":"8.6","Tissue RNA - breast [nTPM]":"16.8","Tissue RNA - cerebellum [nTPM]":"14.0","Tissue RNA - cerebral cortex [nTPM]":"20.1","Tissue RNA - cervix [nTPM]":"33.2","Tissue RNA - choroid plexus [nTPM]":"9.9","Tissue RNA - colon [nTPM]":"49.2","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"38.7","Tissue RNA - epididymis [nTPM]":"13.4","Tissue RNA - esophagus [nTPM]":"11.7","Tissue RNA - fallopian tube [nTPM]":"18.6","Tissue RNA - gallbladder [nTPM]":"20.0","Tissue RNA - heart muscle [nTPM]":"34.8","Tissue RNA - hippocampal formation [nTPM]":"15.2","Tissue RNA - hypothalamus [nTPM]":"22.8","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"9.6","Tissue RNA - medulla oblongata [nTPM]":"21.1","Tissue RNA - midbrain [nTPM]":"19.2","Tissue RNA - ovary [nTPM]":"9.3","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"7.9","Tissue RNA - placenta [nTPM]":"17.5","Tissue RNA - pons [nTPM]":"21.2","Tissue RNA - prostate [nTPM]":"14.5","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"14.8","Tissue RNA - salivary gland [nTPM]":"8.0","Tissue RNA - seminal vesicle [nTPM]":"26.9","Tissue RNA - skeletal muscle [nTPM]":"54.4","Tissue RNA - skin 1 [nTPM]":"7.0","Tissue RNA - small intestine [nTPM]":"11.8","Tissue RNA - smooth muscle [nTPM]":"39.9","Tissue RNA - spinal cord [nTPM]":"16.8","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"18.1","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"18.2","Tissue RNA - thymus [nTPM]":"29.9","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"60.5","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"24.4","Tissue RNA - vagina [nTPM]":"16.4","Tissue RNA - white matter [nTPM]":"18.5","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"11.1","Cell RNA - AF22 [nTPM]":"35.1","Cell RNA - AN3-CA [nTPM]":"43.9","Cell RNA - ASC diff [nTPM]":"58.4","Cell RNA - ASC TERT1 [nTPM]":"113.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"32.7","Cell RNA - BJ hTERT+ [nTPM]":"44.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.3","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"11.3","Cell RNA - EFO-21 [nTPM]":"15.6","Cell RNA - fHDF\/TERT166 [nTPM]":"39.6","Cell RNA - GAMG [nTPM]":"9.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"14.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"11.8","Cell RNA - HDLM-2 [nTPM]":"19.1","Cell RNA - HEK 293 [nTPM]":"7.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"7.0","Cell RNA - Hep G2 [nTPM]":"6.3","Cell RNA - HHSteC [nTPM]":"44.4","Cell RNA - HL-60 [nTPM]":"9.8","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"53.4","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.6","Cell RNA - hTERT-HME1 [nTPM]":"17.6","Cell RNA - hTERT-RPE1 [nTPM]":"21.4","Cell RNA - HUVEC TERT2 [nTPM]":"54.9","Cell RNA - JURKAT [nTPM]":"9.5","Cell RNA - K-562 [nTPM]":"7.5","Cell RNA - Karpas-707 [nTPM]":"14.4","Cell RNA - LHCN-M2 [nTPM]":"42.7","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"33.7","Cell RNA - NB-4 [nTPM]":"6.2","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"11.6","Cell RNA - RH-30 [nTPM]":"66.0","Cell RNA - RPMI-8226 [nTPM]":"5.1","Cell RNA - RPTEC TERT1 [nTPM]":"12.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"15.6","Cell RNA - SiHa [nTPM]":"11.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"7.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"6.7","Cell RNA - TIME [nTPM]":"87.7","Cell RNA - U-138 MG [nTPM]":"40.8","Cell RNA - U-2 OS [nTPM]":"9.4","Cell RNA - U-2197 [nTPM]":"10.0","Cell RNA - U-251 MG [nTPM]":"16.7","Cell RNA - U-266\/70 [nTPM]":"9.1","Cell RNA - U-266\/84 [nTPM]":"6.3","Cell RNA - U-698 [nTPM]":"12.8","Cell RNA - U-87 MG [nTPM]":"10.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.2","Blood RNA - basophil [nTPM]":"4.9","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"5.4","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"4.1","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"6.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.5","Blood RNA - neutrophil [nTPM]":"8.5","Blood RNA - NK-cell [nTPM]":"6.6","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"5.0","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"16.4","Brain RNA - basal ganglia [nTPM]":"16.2","Brain RNA - cerebellum [nTPM]":"14.0","Brain RNA - cerebral cortex [nTPM]":"20.1","Brain RNA - hippocampal formation [nTPM]":"15.2","Brain RNA - hypothalamus [nTPM]":"22.8","Brain RNA - medulla oblongata [nTPM]":"21.1","Brain RNA - midbrain [nTPM]":"19.2","Brain RNA - pons [nTPM]":"21.2","Brain RNA - spinal cord [nTPM]":"16.8","Brain RNA - thalamus [nTPM]":"18.2","Brain RNA - white matter [nTPM]":"18.5","Single Cell Type RNA - Adipocytes [nTPM]":"104.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"212.9","Single Cell Type RNA - B-cells [nTPM]":"34.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"42.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"106.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"22.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"110.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"287.8","Single Cell Type RNA - Endothelial cells [nTPM]":"110.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"276.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"66.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"17.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"13.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"261.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"25.6","Single Cell Type RNA - Late spermatids [nTPM]":"141.8","Single Cell Type RNA - Leydig cells [nTPM]":"30.7","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"479.7","Single Cell Type RNA - monocytes [nTPM]":"10.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.2","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"968.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"102.0","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"43.4","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"99.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"74.2","Single Cell Type RNA - Spermatocytes [nTPM]":"17.4","Single Cell Type RNA - Spermatogonia [nTPM]":"15.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"36.2","Single Cell Type RNA - Theca cells [nTPM]":"12.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"ZFHX2","Gene synonym":["KIAA1056","KIAA1762","ZFH-5","ZNF409"],"Ensembl":"ENSG00000136367","Gene description":"Zinc finger homeobox 2","Uniprot":["Q9C0A1"],"Chromosome":"14","Position":"23520857-23556192","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.9","testis":"7.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"22.5","Early spermatids":"38.9","Excitatory neurons":"31.0","Inhibitory neurons":"20.0","Late spermatids":"19.1","Oligodendrocyte precursor cells":"27.2","Oligodendrocytes":"20.8","Spermatocytes":"16.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"11.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"4.8","SuSa":"3.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000720","HPA005146"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA000720":"AB_10603462","HPA005146":"AB_1859250"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"11.9","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"7.3","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"3.1","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"4.8","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"2.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"2.1","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"2.9","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.3","Cell RNA - RT4 [nTPM]":"1.2","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"3.6","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"11.9","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"9.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.8","Single Cell Type RNA - Early spermatids [nTPM]":"38.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"19.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"16.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"ZFYVE26","Gene synonym":["KIAA0321","SPG15"],"Ensembl":"ENSG00000072121","Gene description":"Zinc finger FYVE-type containing 26","Uniprot":["Q68DK2"],"Chromosome":"14","Position":"67727374-67816590","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"50.1","Rod photoreceptor cells":"126.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"plasmacytoid DC":"4.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"4.8"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055500"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055500":"AB_2682837"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.84e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.54e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"5.5","Tissue RNA - cervix [nTPM]":"5.6","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"4.1","Tissue RNA - endometrium 1 [nTPM]":"5.7","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"4.9","Tissue RNA - liver [nTPM]":"4.4","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"7.0","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"7.3","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"5.9","Tissue RNA - prostate [nTPM]":"4.8","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"4.8","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"8.7","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"6.0","Tissue RNA - spinal cord [nTPM]":"5.0","Tissue RNA - spleen [nTPM]":"7.3","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"7.8","Tissue RNA - thymus [nTPM]":"6.9","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"9.6","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"5.2","Tissue RNA - vagina [nTPM]":"4.8","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"12.1","Cell RNA - A549 [nTPM]":"6.9","Cell RNA - AF22 [nTPM]":"7.3","Cell RNA - AN3-CA [nTPM]":"7.8","Cell RNA - ASC diff [nTPM]":"15.2","Cell RNA - ASC TERT1 [nTPM]":"6.8","Cell RNA - BEWO [nTPM]":"10.7","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"9.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.9","Cell RNA - CACO-2 [nTPM]":"7.2","Cell RNA - CAPAN-2 [nTPM]":"7.3","Cell RNA - Daudi [nTPM]":"6.7","Cell RNA - EFO-21 [nTPM]":"3.0","Cell RNA - fHDF\/TERT166 [nTPM]":"7.4","Cell RNA - GAMG [nTPM]":"10.8","Cell RNA - HaCaT [nTPM]":"7.2","Cell RNA - HAP1 [nTPM]":"10.1","Cell RNA - HBEC3-KT [nTPM]":"6.9","Cell RNA - HBF TERT88 [nTPM]":"10.6","Cell RNA - HDLM-2 [nTPM]":"6.9","Cell RNA - HEK 293 [nTPM]":"5.6","Cell RNA - HEL [nTPM]":"5.1","Cell RNA - HeLa [nTPM]":"8.4","Cell RNA - Hep G2 [nTPM]":"6.7","Cell RNA - HHSteC [nTPM]":"8.4","Cell RNA - HL-60 [nTPM]":"3.1","Cell RNA - HMC-1 [nTPM]":"8.3","Cell RNA - HSkMC [nTPM]":"8.3","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.1","Cell RNA - hTERT-HME1 [nTPM]":"8.1","Cell RNA - hTERT-RPE1 [nTPM]":"6.4","Cell RNA - HUVEC TERT2 [nTPM]":"14.6","Cell RNA - JURKAT [nTPM]":"7.4","Cell RNA - K-562 [nTPM]":"7.6","Cell RNA - Karpas-707 [nTPM]":"5.3","Cell RNA - LHCN-M2 [nTPM]":"8.9","Cell RNA - MCF7 [nTPM]":"9.2","Cell RNA - MOLT-4 [nTPM]":"5.1","Cell RNA - NB-4 [nTPM]":"4.6","Cell RNA - NTERA-2 [nTPM]":"3.8","Cell RNA - OE19 [nTPM]":"4.8","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"4.5","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"3.5","Cell RNA - RPTEC TERT1 [nTPM]":"5.6","Cell RNA - RT4 [nTPM]":"12.2","Cell RNA - SCLC-21H [nTPM]":"7.3","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"9.0","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"8.0","Cell RNA - SuSa [nTPM]":"7.1","Cell RNA - T-47d [nTPM]":"9.8","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"12.9","Cell RNA - U-138 MG [nTPM]":"11.3","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"6.9","Cell RNA - U-251 MG [nTPM]":"4.7","Cell RNA - U-266\/70 [nTPM]":"4.5","Cell RNA - U-266\/84 [nTPM]":"3.3","Cell RNA - U-698 [nTPM]":"8.2","Cell RNA - U-87 MG [nTPM]":"9.3","Cell RNA - U-937 [nTPM]":"5.6","Cell RNA - WM-115 [nTPM]":"5.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"4.8","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"5.5","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"5.9","Brain RNA - spinal cord [nTPM]":"5.0","Brain RNA - thalamus [nTPM]":"7.8","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"4.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"4.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.8","Single Cell Type RNA - dendritic cells [nTPM]":"9.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.9","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.7","Single Cell Type RNA - Endothelial cells [nTPM]":"5.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.4","Single Cell Type RNA - Fibroblasts [nTPM]":"4.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"4.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"6.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"7.5","Single Cell Type RNA - Muller glia cells [nTPM]":"6.9","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.0","Single Cell Type RNA - Paneth cells [nTPM]":"6.2","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"7.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"126.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"3.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"ZFYVE27","Gene synonym":["FLJ32919","SPG33"],"Ensembl":"ENSG00000155256","Gene description":"Zinc finger FYVE-type containing 27","Uniprot":["Q5T4F4"],"Chromosome":"10","Position":"97737121-97760907","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037523","HPA069876"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA037523":"AB_10672351","HPA069876":"AB_2686218"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.91e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.54e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.80e-4"},"Tissue RNA - adipose tissue [nTPM]":"14.4","Tissue RNA - adrenal gland [nTPM]":"27.9","Tissue RNA - amygdala [nTPM]":"33.1","Tissue RNA - appendix [nTPM]":"12.9","Tissue RNA - basal ganglia [nTPM]":"32.1","Tissue RNA - bone marrow [nTPM]":"23.2","Tissue RNA - breast [nTPM]":"15.8","Tissue RNA - cerebellum [nTPM]":"29.2","Tissue RNA - cerebral cortex [nTPM]":"35.9","Tissue RNA - cervix [nTPM]":"20.6","Tissue RNA - choroid plexus [nTPM]":"34.8","Tissue RNA - colon [nTPM]":"25.6","Tissue RNA - duodenum [nTPM]":"24.8","Tissue RNA - endometrium 1 [nTPM]":"16.5","Tissue RNA - epididymis [nTPM]":"22.9","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"20.3","Tissue RNA - gallbladder [nTPM]":"12.1","Tissue RNA - heart muscle [nTPM]":"17.8","Tissue RNA - hippocampal formation [nTPM]":"35.5","Tissue RNA - hypothalamus [nTPM]":"33.6","Tissue RNA - kidney [nTPM]":"28.3","Tissue RNA - liver [nTPM]":"32.6","Tissue RNA - lung [nTPM]":"17.7","Tissue RNA - lymph node [nTPM]":"16.1","Tissue RNA - medulla oblongata [nTPM]":"32.6","Tissue RNA - midbrain [nTPM]":"31.4","Tissue RNA - ovary [nTPM]":"25.9","Tissue RNA - pancreas [nTPM]":"23.7","Tissue RNA - parathyroid gland [nTPM]":"19.2","Tissue RNA - pituitary gland [nTPM]":"38.3","Tissue RNA - placenta [nTPM]":"9.5","Tissue RNA - pons [nTPM]":"33.2","Tissue RNA - prostate [nTPM]":"22.0","Tissue RNA - rectum [nTPM]":"16.3","Tissue RNA - retina [nTPM]":"28.4","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"12.8","Tissue RNA - skin 1 [nTPM]":"18.2","Tissue RNA - small intestine [nTPM]":"30.6","Tissue RNA - smooth muscle [nTPM]":"8.5","Tissue RNA - spinal cord [nTPM]":"29.1","Tissue RNA - spleen [nTPM]":"29.1","Tissue RNA - stomach 1 [nTPM]":"19.8","Tissue RNA - testis [nTPM]":"23.0","Tissue RNA - thalamus [nTPM]":"33.5","Tissue RNA - thymus [nTPM]":"12.7","Tissue RNA - thyroid gland [nTPM]":"20.4","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"13.1","Tissue RNA - urinary bladder [nTPM]":"16.8","Tissue RNA - vagina [nTPM]":"17.0","Tissue RNA - white matter [nTPM]":"32.4","Cell RNA - A-431 [nTPM]":"17.7","Cell RNA - A549 [nTPM]":"21.4","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"28.1","Cell RNA - ASC diff [nTPM]":"14.1","Cell RNA - ASC TERT1 [nTPM]":"9.8","Cell RNA - BEWO [nTPM]":"17.2","Cell RNA - BJ [nTPM]":"17.7","Cell RNA - BJ hTERT+ [nTPM]":"18.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.7","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"35.9","Cell RNA - Daudi [nTPM]":"27.2","Cell RNA - EFO-21 [nTPM]":"19.8","Cell RNA - fHDF\/TERT166 [nTPM]":"12.8","Cell RNA - GAMG [nTPM]":"25.9","Cell RNA - HaCaT [nTPM]":"38.8","Cell RNA - HAP1 [nTPM]":"18.4","Cell RNA - HBEC3-KT [nTPM]":"17.2","Cell RNA - HBF TERT88 [nTPM]":"10.6","Cell RNA - HDLM-2 [nTPM]":"28.3","Cell RNA - HEK 293 [nTPM]":"18.6","Cell RNA - HEL [nTPM]":"12.9","Cell RNA - HeLa [nTPM]":"23.1","Cell RNA - Hep G2 [nTPM]":"18.1","Cell RNA - HHSteC [nTPM]":"18.1","Cell RNA - HL-60 [nTPM]":"20.9","Cell RNA - HMC-1 [nTPM]":"24.9","Cell RNA - HSkMC [nTPM]":"16.0","Cell RNA - hTCEpi [nTPM]":"20.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.9","Cell RNA - hTERT-HME1 [nTPM]":"15.2","Cell RNA - hTERT-RPE1 [nTPM]":"32.4","Cell RNA - HUVEC TERT2 [nTPM]":"11.5","Cell RNA - JURKAT [nTPM]":"22.5","Cell RNA - K-562 [nTPM]":"19.6","Cell RNA - Karpas-707 [nTPM]":"17.9","Cell RNA - LHCN-M2 [nTPM]":"15.3","Cell RNA - MCF7 [nTPM]":"13.8","Cell RNA - MOLT-4 [nTPM]":"16.9","Cell RNA - NB-4 [nTPM]":"39.4","Cell RNA - NTERA-2 [nTPM]":"10.3","Cell RNA - OE19 [nTPM]":"15.3","Cell RNA - PC-3 [nTPM]":"16.4","Cell RNA - REH [nTPM]":"19.2","Cell RNA - RH-30 [nTPM]":"12.7","Cell RNA - RPMI-8226 [nTPM]":"13.0","Cell RNA - RPTEC TERT1 [nTPM]":"19.5","Cell RNA - RT4 [nTPM]":"10.8","Cell RNA - SCLC-21H [nTPM]":"10.1","Cell RNA - SH-SY5Y [nTPM]":"19.7","Cell RNA - SiHa [nTPM]":"11.9","Cell RNA - SK-BR-3 [nTPM]":"9.9","Cell RNA - SK-MEL-30 [nTPM]":"47.2","Cell RNA - SuSa [nTPM]":"11.5","Cell RNA - T-47d [nTPM]":"21.8","Cell RNA - THP-1 [nTPM]":"20.5","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"10.2","Cell RNA - U-2 OS [nTPM]":"11.9","Cell RNA - U-2197 [nTPM]":"15.6","Cell RNA - U-251 MG [nTPM]":"34.2","Cell RNA - U-266\/70 [nTPM]":"20.6","Cell RNA - U-266\/84 [nTPM]":"18.6","Cell RNA - U-698 [nTPM]":"14.3","Cell RNA - U-87 MG [nTPM]":"25.3","Cell RNA - U-937 [nTPM]":"26.5","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"4.8","Blood RNA - classical monocyte [nTPM]":"5.8","Blood RNA - eosinophil [nTPM]":"9.3","Blood RNA - gdT-cell [nTPM]":"9.6","Blood RNA - intermediate monocyte [nTPM]":"6.2","Blood RNA - MAIT T-cell [nTPM]":"8.2","Blood RNA - memory B-cell [nTPM]":"7.1","Blood RNA - memory CD4 T-cell [nTPM]":"6.6","Blood RNA - memory CD8 T-cell [nTPM]":"7.9","Blood RNA - myeloid DC [nTPM]":"5.4","Blood RNA - naive B-cell [nTPM]":"6.7","Blood RNA - naive CD4 T-cell [nTPM]":"7.5","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"8.2","Blood RNA - NK-cell [nTPM]":"6.8","Blood RNA - non-classical monocyte [nTPM]":"9.2","Blood RNA - plasmacytoid DC [nTPM]":"5.6","Blood RNA - T-reg [nTPM]":"9.5","Blood RNA - total PBMC [nTPM]":"8.3","Brain RNA - amygdala [nTPM]":"33.1","Brain RNA - basal ganglia [nTPM]":"32.1","Brain RNA - cerebellum [nTPM]":"29.2","Brain RNA - cerebral cortex [nTPM]":"35.9","Brain RNA - hippocampal formation [nTPM]":"35.5","Brain RNA - hypothalamus [nTPM]":"33.6","Brain RNA - medulla oblongata [nTPM]":"32.6","Brain RNA - midbrain [nTPM]":"31.4","Brain RNA - pons [nTPM]":"33.2","Brain RNA - spinal cord [nTPM]":"29.1","Brain RNA - thalamus [nTPM]":"33.5","Brain RNA - white matter [nTPM]":"32.4","Single Cell Type RNA - Adipocytes [nTPM]":"10.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.4","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"22.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"29.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"9.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - dendritic cells [nTPM]":"21.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.9","Single Cell Type RNA - Early spermatids [nTPM]":"5.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"11.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.4","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"17.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"10.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.2","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"11.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"11.2","Single Cell Type RNA - Muller glia cells [nTPM]":"14.8","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.9","Single Cell Type RNA - Paneth cells [nTPM]":"26.1","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"43.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.9","Single Cell Type RNA - Spermatocytes [nTPM]":"8.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.5","Single Cell Type RNA - T-cells [nTPM]":"17.9","Single Cell Type RNA - Theca cells [nTPM]":"10.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.7"},{"Gene":"ZNF408","Gene synonym":["FLJ12827"],"Ensembl":"ENSG00000175213","Gene description":"Zinc finger protein 408","Uniprot":["Q9H9D4"],"Chromosome":"11","Position":"46701030-46705912","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017892"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017892":"AB_1859248"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.59e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.9","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"6.6","Tissue RNA - bone marrow [nTPM]":"14.5","Tissue RNA - breast [nTPM]":"5.6","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"4.7","Tissue RNA - colon [nTPM]":"6.6","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"7.8","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"5.8","Tissue RNA - kidney [nTPM]":"5.9","Tissue RNA - liver [nTPM]":"12.7","Tissue RNA - lung [nTPM]":"3.9","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"6.7","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"3.2","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"5.7","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"10.3","Tissue RNA - skin 1 [nTPM]":"10.1","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"3.4","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"7.5","Tissue RNA - stomach 1 [nTPM]":"7.4","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"5.4","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"6.2","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"7.2","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"4.8","Cell RNA - A549 [nTPM]":"11.4","Cell RNA - AF22 [nTPM]":"5.2","Cell RNA - AN3-CA [nTPM]":"9.4","Cell RNA - ASC diff [nTPM]":"6.5","Cell RNA - ASC TERT1 [nTPM]":"5.7","Cell RNA - BEWO [nTPM]":"13.5","Cell RNA - BJ [nTPM]":"6.3","Cell RNA - BJ hTERT+ [nTPM]":"8.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"10.3","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"7.4","Cell RNA - EFO-21 [nTPM]":"5.7","Cell RNA - fHDF\/TERT166 [nTPM]":"7.6","Cell RNA - GAMG [nTPM]":"9.0","Cell RNA - HaCaT [nTPM]":"12.2","Cell RNA - HAP1 [nTPM]":"6.7","Cell RNA - HBEC3-KT [nTPM]":"12.4","Cell RNA - HBF TERT88 [nTPM]":"4.4","Cell RNA - HDLM-2 [nTPM]":"5.9","Cell RNA - HEK 293 [nTPM]":"13.5","Cell RNA - HEL [nTPM]":"7.1","Cell RNA - HeLa [nTPM]":"8.0","Cell RNA - Hep G2 [nTPM]":"12.7","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"7.4","Cell RNA - HMC-1 [nTPM]":"9.7","Cell RNA - HSkMC [nTPM]":"11.2","Cell RNA - hTCEpi [nTPM]":"12.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.3","Cell RNA - hTERT-HME1 [nTPM]":"9.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.7","Cell RNA - HUVEC TERT2 [nTPM]":"6.2","Cell RNA - JURKAT [nTPM]":"11.1","Cell RNA - K-562 [nTPM]":"11.4","Cell RNA - Karpas-707 [nTPM]":"6.5","Cell RNA - LHCN-M2 [nTPM]":"5.2","Cell RNA - MCF7 [nTPM]":"15.5","Cell RNA - MOLT-4 [nTPM]":"9.0","Cell RNA - NB-4 [nTPM]":"15.1","Cell RNA - NTERA-2 [nTPM]":"21.8","Cell RNA - OE19 [nTPM]":"15.9","Cell RNA - PC-3 [nTPM]":"13.8","Cell RNA - REH [nTPM]":"9.8","Cell RNA - RH-30 [nTPM]":"7.8","Cell RNA - RPMI-8226 [nTPM]":"11.7","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"12.5","Cell RNA - SCLC-21H [nTPM]":"7.3","Cell RNA - SH-SY5Y [nTPM]":"9.8","Cell RNA - SiHa [nTPM]":"12.1","Cell RNA - SK-BR-3 [nTPM]":"15.0","Cell RNA - SK-MEL-30 [nTPM]":"10.0","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"13.1","Cell RNA - THP-1 [nTPM]":"12.9","Cell RNA - TIME [nTPM]":"7.1","Cell RNA - U-138 MG [nTPM]":"12.2","Cell RNA - U-2 OS [nTPM]":"8.1","Cell RNA - U-2197 [nTPM]":"10.2","Cell RNA - U-251 MG [nTPM]":"12.4","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"8.8","Cell RNA - U-698 [nTPM]":"10.9","Cell RNA - U-87 MG [nTPM]":"7.9","Cell RNA - U-937 [nTPM]":"8.5","Cell RNA - WM-115 [nTPM]":"9.9","Blood RNA - basophil [nTPM]":"3.9","Blood RNA - classical monocyte [nTPM]":"7.6","Blood RNA - eosinophil [nTPM]":"7.8","Blood RNA - gdT-cell [nTPM]":"8.5","Blood RNA - intermediate monocyte [nTPM]":"8.3","Blood RNA - MAIT T-cell [nTPM]":"6.6","Blood RNA - memory B-cell [nTPM]":"6.3","Blood RNA - memory CD4 T-cell [nTPM]":"8.3","Blood RNA - memory CD8 T-cell [nTPM]":"10.2","Blood RNA - myeloid DC [nTPM]":"7.2","Blood RNA - naive B-cell [nTPM]":"7.6","Blood RNA - naive CD4 T-cell [nTPM]":"9.2","Blood RNA - naive CD8 T-cell [nTPM]":"7.0","Blood RNA - neutrophil [nTPM]":"7.1","Blood RNA - NK-cell [nTPM]":"5.8","Blood RNA - non-classical monocyte [nTPM]":"6.3","Blood RNA - plasmacytoid DC [nTPM]":"5.7","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"6.6","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"5.8","Brain RNA - medulla oblongata [nTPM]":"6.7","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"7.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"7.8","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"11.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"9.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"3.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"6.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.9","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.9","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"5.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"11.2","Single Cell Type RNA - Spermatogonia [nTPM]":"9.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.5","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.0"},{"Gene":"ZNF513","Gene synonym":["FLJ32203","RP58","Zfp513"],"Ensembl":"ENSG00000163795","Gene description":"Zinc finger protein 513","Uniprot":["Q8N8E2"],"Chromosome":"2","Position":"27377235-27380790","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Sensory transduction","Transcription","Transcription regulation","Vision"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"44.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SH-SY5Y":"50.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051493"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051493":"AB_2681505"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.21e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Tissue RNA - adipose tissue [nTPM]":"16.2","Tissue RNA - adrenal gland [nTPM]":"23.7","Tissue RNA - amygdala [nTPM]":"15.7","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"12.1","Tissue RNA - breast [nTPM]":"16.7","Tissue RNA - cerebellum [nTPM]":"17.5","Tissue RNA - cerebral cortex [nTPM]":"19.2","Tissue RNA - cervix [nTPM]":"16.6","Tissue RNA - choroid plexus [nTPM]":"12.6","Tissue RNA - colon [nTPM]":"22.5","Tissue RNA - duodenum [nTPM]":"18.7","Tissue RNA - endometrium 1 [nTPM]":"18.2","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"23.8","Tissue RNA - fallopian tube [nTPM]":"16.7","Tissue RNA - gallbladder [nTPM]":"9.3","Tissue RNA - heart muscle [nTPM]":"14.3","Tissue RNA - hippocampal formation [nTPM]":"15.2","Tissue RNA - hypothalamus [nTPM]":"14.2","Tissue RNA - kidney [nTPM]":"27.3","Tissue RNA - liver [nTPM]":"38.5","Tissue RNA - lung [nTPM]":"18.2","Tissue RNA - lymph node [nTPM]":"11.1","Tissue RNA - medulla oblongata [nTPM]":"15.5","Tissue RNA - midbrain [nTPM]":"15.4","Tissue RNA - ovary [nTPM]":"13.4","Tissue RNA - pancreas [nTPM]":"20.5","Tissue RNA - parathyroid gland [nTPM]":"10.1","Tissue RNA - pituitary gland [nTPM]":"30.2","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"14.4","Tissue RNA - prostate [nTPM]":"25.8","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"4.8","Tissue RNA - salivary gland [nTPM]":"18.7","Tissue RNA - seminal vesicle [nTPM]":"10.6","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"19.5","Tissue RNA - small intestine [nTPM]":"23.6","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"14.1","Tissue RNA - spleen [nTPM]":"27.2","Tissue RNA - stomach 1 [nTPM]":"24.2","Tissue RNA - testis [nTPM]":"36.1","Tissue RNA - thalamus [nTPM]":"16.6","Tissue RNA - thymus [nTPM]":"8.7","Tissue RNA - thyroid gland [nTPM]":"23.5","Tissue RNA - tongue [nTPM]":"5.4","Tissue RNA - tonsil [nTPM]":"6.5","Tissue RNA - urinary bladder [nTPM]":"19.4","Tissue RNA - vagina [nTPM]":"17.2","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"10.3","Cell RNA - A549 [nTPM]":"12.4","Cell RNA - AF22 [nTPM]":"15.7","Cell RNA - AN3-CA [nTPM]":"16.0","Cell RNA - ASC diff [nTPM]":"10.3","Cell RNA - ASC TERT1 [nTPM]":"8.6","Cell RNA - BEWO [nTPM]":"20.6","Cell RNA - BJ [nTPM]":"13.1","Cell RNA - BJ hTERT+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.3","Cell RNA - CACO-2 [nTPM]":"10.2","Cell RNA - CAPAN-2 [nTPM]":"7.6","Cell RNA - Daudi [nTPM]":"3.5","Cell RNA - EFO-21 [nTPM]":"11.6","Cell RNA - fHDF\/TERT166 [nTPM]":"9.4","Cell RNA - GAMG [nTPM]":"10.1","Cell RNA - HaCaT [nTPM]":"9.1","Cell RNA - HAP1 [nTPM]":"6.7","Cell RNA - HBEC3-KT [nTPM]":"11.8","Cell RNA - HBF TERT88 [nTPM]":"2.8","Cell RNA - HDLM-2 [nTPM]":"13.0","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"9.9","Cell RNA - HeLa [nTPM]":"8.9","Cell RNA - Hep G2 [nTPM]":"7.7","Cell RNA - HHSteC [nTPM]":"18.3","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"26.6","Cell RNA - HSkMC [nTPM]":"14.7","Cell RNA - hTCEpi [nTPM]":"13.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"11.5","Cell RNA - hTERT-RPE1 [nTPM]":"6.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.4","Cell RNA - JURKAT [nTPM]":"13.8","Cell RNA - K-562 [nTPM]":"6.2","Cell RNA - Karpas-707 [nTPM]":"2.1","Cell RNA - LHCN-M2 [nTPM]":"9.2","Cell RNA - MCF7 [nTPM]":"3.9","Cell RNA - MOLT-4 [nTPM]":"6.4","Cell RNA - NB-4 [nTPM]":"16.6","Cell RNA - NTERA-2 [nTPM]":"23.7","Cell RNA - OE19 [nTPM]":"9.9","Cell RNA - PC-3 [nTPM]":"8.0","Cell RNA - REH [nTPM]":"8.2","Cell RNA - RH-30 [nTPM]":"11.7","Cell RNA - RPMI-8226 [nTPM]":"6.6","Cell RNA - RPTEC TERT1 [nTPM]":"13.5","Cell RNA - RT4 [nTPM]":"17.8","Cell RNA - SCLC-21H [nTPM]":"9.7","Cell RNA - SH-SY5Y [nTPM]":"50.8","Cell RNA - SiHa [nTPM]":"6.4","Cell RNA - SK-BR-3 [nTPM]":"7.4","Cell RNA - SK-MEL-30 [nTPM]":"12.9","Cell RNA - SuSa [nTPM]":"8.5","Cell RNA - T-47d [nTPM]":"5.5","Cell RNA - THP-1 [nTPM]":"9.8","Cell RNA - TIME [nTPM]":"10.9","Cell RNA - U-138 MG [nTPM]":"6.7","Cell RNA - U-2 OS [nTPM]":"4.4","Cell RNA - U-2197 [nTPM]":"5.5","Cell RNA - U-251 MG [nTPM]":"3.9","Cell RNA - U-266\/70 [nTPM]":"30.1","Cell RNA - U-266\/84 [nTPM]":"19.9","Cell RNA - U-698 [nTPM]":"6.6","Cell RNA - U-87 MG [nTPM]":"9.3","Cell RNA - U-937 [nTPM]":"8.0","Cell RNA - WM-115 [nTPM]":"13.5","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"15.7","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"17.5","Brain RNA - cerebral cortex [nTPM]":"19.2","Brain RNA - hippocampal formation [nTPM]":"15.2","Brain RNA - hypothalamus [nTPM]":"14.2","Brain RNA - medulla oblongata [nTPM]":"15.5","Brain RNA - midbrain [nTPM]":"15.4","Brain RNA - pons [nTPM]":"14.4","Brain RNA - spinal cord [nTPM]":"14.1","Brain RNA - thalamus [nTPM]":"16.6","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"7.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"7.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"4.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.2","Single Cell Type RNA - Early spermatids [nTPM]":"44.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"7.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"10.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"10.5","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"5.9","Single Cell Type RNA - Muller glia cells [nTPM]":"11.7","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.0","Single Cell Type RNA - Paneth cells [nTPM]":"13.5","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"4.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.2","Single Cell Type RNA - Spermatocytes [nTPM]":"9.3","Single Cell Type RNA - Spermatogonia [nTPM]":"10.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.1","Single Cell Type RNA - T-cells [nTPM]":"4.5","Single Cell Type RNA - Theca cells [nTPM]":"10.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.4","Single Cell Type RNA - Urothelial cells [nTPM]":"13.6"},{"Gene":"ZNF644","Gene synonym":["BM-005","KIAA1221","MGC60165","MGC70410"],"Ensembl":"ENSG00000122482","Gene description":"Zinc finger protein 644","Uniprot":["Q9H582"],"Chromosome":"1","Position":"90915298-91022272","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"262.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057795"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA057795":"AB_2683529"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.39e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"12.4","Tissue RNA - adrenal gland [nTPM]":"9.8","Tissue RNA - amygdala [nTPM]":"17.4","Tissue RNA - appendix [nTPM]":"11.7","Tissue RNA - basal ganglia [nTPM]":"23.4","Tissue RNA - bone marrow [nTPM]":"17.3","Tissue RNA - breast [nTPM]":"17.1","Tissue RNA - cerebellum [nTPM]":"24.5","Tissue RNA - cerebral cortex [nTPM]":"22.3","Tissue RNA - cervix [nTPM]":"15.7","Tissue RNA - choroid plexus [nTPM]":"13.3","Tissue RNA - colon [nTPM]":"13.3","Tissue RNA - duodenum [nTPM]":"8.5","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"11.4","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"10.9","Tissue RNA - gallbladder [nTPM]":"10.2","Tissue RNA - heart muscle [nTPM]":"10.0","Tissue RNA - hippocampal formation [nTPM]":"15.3","Tissue RNA - hypothalamus [nTPM]":"18.0","Tissue RNA - kidney [nTPM]":"11.0","Tissue RNA - liver [nTPM]":"19.8","Tissue RNA - lung [nTPM]":"10.3","Tissue RNA - lymph node [nTPM]":"15.9","Tissue RNA - medulla oblongata [nTPM]":"19.0","Tissue RNA - midbrain [nTPM]":"20.8","Tissue RNA - ovary [nTPM]":"14.7","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"12.6","Tissue RNA - pituitary gland [nTPM]":"7.9","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"19.4","Tissue RNA - prostate [nTPM]":"11.6","Tissue RNA - rectum [nTPM]":"13.4","Tissue RNA - retina [nTPM]":"11.2","Tissue RNA - salivary gland [nTPM]":"15.4","Tissue RNA - seminal vesicle [nTPM]":"10.4","Tissue RNA - skeletal muscle [nTPM]":"14.5","Tissue RNA - skin 1 [nTPM]":"10.4","Tissue RNA - small intestine [nTPM]":"10.5","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"18.8","Tissue RNA - spleen [nTPM]":"13.2","Tissue RNA - stomach 1 [nTPM]":"10.5","Tissue RNA - testis [nTPM]":"13.1","Tissue RNA - thalamus [nTPM]":"18.6","Tissue RNA - thymus [nTPM]":"19.7","Tissue RNA - thyroid gland [nTPM]":"18.7","Tissue RNA - tongue [nTPM]":"17.4","Tissue RNA - tonsil [nTPM]":"15.3","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"12.1","Tissue RNA - white matter [nTPM]":"28.4","Cell RNA - A-431 [nTPM]":"24.1","Cell RNA - A549 [nTPM]":"11.2","Cell RNA - AF22 [nTPM]":"32.0","Cell RNA - AN3-CA [nTPM]":"17.1","Cell RNA - ASC diff [nTPM]":"14.9","Cell RNA - ASC TERT1 [nTPM]":"17.1","Cell RNA - BEWO [nTPM]":"19.4","Cell RNA - BJ [nTPM]":"21.0","Cell RNA - BJ hTERT+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.1","Cell RNA - CACO-2 [nTPM]":"15.4","Cell RNA - CAPAN-2 [nTPM]":"8.3","Cell RNA - Daudi [nTPM]":"29.0","Cell RNA - EFO-21 [nTPM]":"23.2","Cell RNA - fHDF\/TERT166 [nTPM]":"15.6","Cell RNA - GAMG [nTPM]":"29.3","Cell RNA - HaCaT [nTPM]":"19.1","Cell RNA - HAP1 [nTPM]":"31.6","Cell RNA - HBEC3-KT [nTPM]":"23.7","Cell RNA - HBF TERT88 [nTPM]":"33.4","Cell RNA - HDLM-2 [nTPM]":"21.5","Cell RNA - HEK 293 [nTPM]":"19.8","Cell RNA - HEL [nTPM]":"38.3","Cell RNA - HeLa [nTPM]":"21.8","Cell RNA - Hep G2 [nTPM]":"21.1","Cell RNA - HHSteC [nTPM]":"20.6","Cell RNA - HL-60 [nTPM]":"34.6","Cell RNA - HMC-1 [nTPM]":"11.9","Cell RNA - HSkMC [nTPM]":"16.3","Cell RNA - hTCEpi [nTPM]":"27.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.4","Cell RNA - hTERT-HME1 [nTPM]":"30.1","Cell RNA - hTERT-RPE1 [nTPM]":"20.8","Cell RNA - HUVEC TERT2 [nTPM]":"23.8","Cell RNA - JURKAT [nTPM]":"21.6","Cell RNA - K-562 [nTPM]":"26.8","Cell RNA - Karpas-707 [nTPM]":"32.0","Cell RNA - LHCN-M2 [nTPM]":"23.6","Cell RNA - MCF7 [nTPM]":"9.5","Cell RNA - MOLT-4 [nTPM]":"27.9","Cell RNA - NB-4 [nTPM]":"30.0","Cell RNA - NTERA-2 [nTPM]":"30.3","Cell RNA - OE19 [nTPM]":"12.5","Cell RNA - PC-3 [nTPM]":"22.7","Cell RNA - REH [nTPM]":"28.7","Cell RNA - RH-30 [nTPM]":"52.3","Cell RNA - RPMI-8226 [nTPM]":"16.6","Cell RNA - RPTEC TERT1 [nTPM]":"23.5","Cell RNA - RT4 [nTPM]":"21.5","Cell RNA - SCLC-21H [nTPM]":"25.8","Cell RNA - SH-SY5Y [nTPM]":"20.6","Cell RNA - SiHa [nTPM]":"24.5","Cell RNA - SK-BR-3 [nTPM]":"19.1","Cell RNA - SK-MEL-30 [nTPM]":"55.2","Cell RNA - SuSa [nTPM]":"21.7","Cell RNA - T-47d [nTPM]":"12.4","Cell RNA - THP-1 [nTPM]":"33.7","Cell RNA - TIME [nTPM]":"19.0","Cell RNA - U-138 MG [nTPM]":"24.5","Cell RNA - U-2 OS [nTPM]":"21.3","Cell RNA - U-2197 [nTPM]":"20.4","Cell RNA - U-251 MG [nTPM]":"31.9","Cell RNA - U-266\/70 [nTPM]":"24.5","Cell RNA - U-266\/84 [nTPM]":"17.8","Cell RNA - U-698 [nTPM]":"39.7","Cell RNA - U-87 MG [nTPM]":"10.3","Cell RNA - U-937 [nTPM]":"25.8","Cell RNA - WM-115 [nTPM]":"12.9","Blood RNA - basophil [nTPM]":"5.4","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"4.6","Blood RNA - intermediate monocyte [nTPM]":"3.6","Blood RNA - MAIT T-cell [nTPM]":"5.3","Blood RNA - memory B-cell [nTPM]":"6.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.0","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"4.4","Blood RNA - naive B-cell [nTPM]":"5.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.4","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"9.9","Blood RNA - non-classical monocyte [nTPM]":"3.8","Blood RNA - plasmacytoid DC [nTPM]":"5.4","Blood RNA - T-reg [nTPM]":"4.4","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"17.4","Brain RNA - basal ganglia [nTPM]":"23.4","Brain RNA - cerebellum [nTPM]":"24.5","Brain RNA - cerebral cortex [nTPM]":"22.3","Brain RNA - hippocampal formation [nTPM]":"15.3","Brain RNA - hypothalamus [nTPM]":"18.0","Brain RNA - medulla oblongata [nTPM]":"19.0","Brain RNA - midbrain [nTPM]":"20.8","Brain RNA - pons [nTPM]":"19.4","Brain RNA - spinal cord [nTPM]":"18.8","Brain RNA - thalamus [nTPM]":"18.6","Brain RNA - white matter [nTPM]":"28.4","Single Cell Type RNA - Adipocytes [nTPM]":"72.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.0","Single Cell Type RNA - Astrocytes [nTPM]":"98.9","Single Cell Type RNA - B-cells [nTPM]":"85.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"98.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"45.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"48.3","Single Cell Type RNA - Bipolar cells [nTPM]":"37.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"51.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"47.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.6","Single Cell Type RNA - dendritic cells [nTPM]":"85.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"31.1","Single Cell Type RNA - Early spermatids [nTPM]":"11.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"87.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"68.7","Single Cell Type RNA - Endothelial cells [nTPM]":"44.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"55.0","Single Cell Type RNA - Erythroid cells [nTPM]":"30.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"96.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.6","Single Cell Type RNA - Fibroblasts [nTPM]":"51.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"107.9","Single Cell Type RNA - granulocytes [nTPM]":"43.2","Single Cell Type RNA - Granulosa cells [nTPM]":"51.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.1","Single Cell Type RNA - Hepatocytes [nTPM]":"26.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.5","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"106.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.4","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"29.2","Single Cell Type RNA - Langerhans cells [nTPM]":"38.6","Single Cell Type RNA - Late spermatids [nTPM]":"13.3","Single Cell Type RNA - Leydig cells [nTPM]":"46.6","Single Cell Type RNA - Macrophages [nTPM]":"49.7","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"124.6","Single Cell Type RNA - monocytes [nTPM]":"30.7","Single Cell Type RNA - Muller glia cells [nTPM]":"40.2","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"144.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"262.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.6","Single Cell Type RNA - Paneth cells [nTPM]":"29.2","Single Cell Type RNA - Peritubular cells [nTPM]":"34.6","Single Cell Type RNA - Plasma cells [nTPM]":"79.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"58.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"41.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.8","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"83.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"67.4","Single Cell Type RNA - Spermatocytes [nTPM]":"51.5","Single Cell Type RNA - Spermatogonia [nTPM]":"49.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"47.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - T-cells [nTPM]":"72.9","Single Cell Type RNA - Theca cells [nTPM]":"44.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.0","Single Cell Type RNA - Urothelial cells [nTPM]":"75.2"},{"Gene":"ZNHIT3","Gene synonym":["Hit1","TRIP3"],"Ensembl":"ENSG00000273611","Gene description":"Zinc finger HIT-type containing 3","Uniprot":["Q15649"],"Chromosome":"17","Position":"36486629-36499310","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"222.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060019","HPA078211"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA060019":"AB_2684188","HPA078211":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.4","Tissue RNA - adrenal gland [nTPM]":"32.4","Tissue RNA - amygdala [nTPM]":"33.4","Tissue RNA - appendix [nTPM]":"17.6","Tissue RNA - basal ganglia [nTPM]":"34.9","Tissue RNA - bone marrow [nTPM]":"31.2","Tissue RNA - breast [nTPM]":"32.7","Tissue RNA - cerebellum [nTPM]":"33.6","Tissue RNA - cerebral cortex [nTPM]":"43.1","Tissue RNA - cervix [nTPM]":"26.2","Tissue RNA - choroid plexus [nTPM]":"31.3","Tissue RNA - colon [nTPM]":"30.9","Tissue RNA - duodenum [nTPM]":"24.1","Tissue RNA - endometrium 1 [nTPM]":"24.6","Tissue RNA - epididymis [nTPM]":"39.9","Tissue RNA - esophagus [nTPM]":"30.4","Tissue RNA - fallopian tube [nTPM]":"24.0","Tissue RNA - gallbladder [nTPM]":"20.1","Tissue RNA - heart muscle [nTPM]":"27.2","Tissue RNA - hippocampal formation [nTPM]":"33.9","Tissue RNA - hypothalamus [nTPM]":"35.1","Tissue RNA - kidney [nTPM]":"35.1","Tissue RNA - liver [nTPM]":"35.9","Tissue RNA - lung [nTPM]":"19.4","Tissue RNA - lymph node [nTPM]":"39.1","Tissue RNA - medulla oblongata [nTPM]":"33.5","Tissue RNA - midbrain [nTPM]":"34.0","Tissue RNA - ovary [nTPM]":"31.1","Tissue RNA - pancreas [nTPM]":"33.1","Tissue RNA - parathyroid gland [nTPM]":"27.4","Tissue RNA - pituitary gland [nTPM]":"24.0","Tissue RNA - placenta [nTPM]":"21.0","Tissue RNA - pons [nTPM]":"33.9","Tissue RNA - prostate [nTPM]":"26.3","Tissue RNA - rectum [nTPM]":"30.5","Tissue RNA - retina [nTPM]":"19.5","Tissue RNA - salivary gland [nTPM]":"26.3","Tissue RNA - seminal vesicle [nTPM]":"20.0","Tissue RNA - skeletal muscle [nTPM]":"58.0","Tissue RNA - skin 1 [nTPM]":"30.9","Tissue RNA - small intestine [nTPM]":"24.1","Tissue RNA - smooth muscle [nTPM]":"18.9","Tissue RNA - spinal cord [nTPM]":"35.2","Tissue RNA - spleen [nTPM]":"25.5","Tissue RNA - stomach 1 [nTPM]":"28.2","Tissue RNA - testis [nTPM]":"50.4","Tissue RNA - thalamus [nTPM]":"33.4","Tissue RNA - thymus [nTPM]":"29.4","Tissue RNA - thyroid gland [nTPM]":"28.7","Tissue RNA - tongue [nTPM]":"32.4","Tissue RNA - tonsil [nTPM]":"39.7","Tissue RNA - urinary bladder [nTPM]":"30.0","Tissue RNA - vagina [nTPM]":"26.5","Tissue RNA - white matter [nTPM]":"35.6","Cell RNA - A-431 [nTPM]":"39.6","Cell RNA - A549 [nTPM]":"39.0","Cell RNA - AF22 [nTPM]":"70.4","Cell RNA - AN3-CA [nTPM]":"55.1","Cell RNA - ASC diff [nTPM]":"38.6","Cell RNA - ASC TERT1 [nTPM]":"49.4","Cell RNA - BEWO [nTPM]":"38.8","Cell RNA - BJ [nTPM]":"35.8","Cell RNA - BJ hTERT+ [nTPM]":"56.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"53.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.2","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"55.7","Cell RNA - Daudi [nTPM]":"67.3","Cell RNA - EFO-21 [nTPM]":"38.8","Cell RNA - fHDF\/TERT166 [nTPM]":"18.0","Cell RNA - GAMG [nTPM]":"66.8","Cell RNA - HaCaT [nTPM]":"37.1","Cell RNA - HAP1 [nTPM]":"25.7","Cell RNA - HBEC3-KT [nTPM]":"30.8","Cell RNA - HBF TERT88 [nTPM]":"66.5","Cell RNA - HDLM-2 [nTPM]":"35.3","Cell RNA - HEK 293 [nTPM]":"25.7","Cell RNA - HEL [nTPM]":"27.2","Cell RNA - HeLa [nTPM]":"41.1","Cell RNA - Hep G2 [nTPM]":"54.3","Cell RNA - HHSteC [nTPM]":"28.2","Cell RNA - HL-60 [nTPM]":"73.0","Cell RNA - HMC-1 [nTPM]":"37.7","Cell RNA - HSkMC [nTPM]":"34.4","Cell RNA - hTCEpi [nTPM]":"69.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.1","Cell RNA - hTERT-HME1 [nTPM]":"53.6","Cell RNA - hTERT-RPE1 [nTPM]":"60.3","Cell RNA - HUVEC TERT2 [nTPM]":"37.1","Cell RNA - JURKAT [nTPM]":"79.6","Cell RNA - K-562 [nTPM]":"48.5","Cell RNA - Karpas-707 [nTPM]":"39.8","Cell RNA - LHCN-M2 [nTPM]":"58.3","Cell RNA - MCF7 [nTPM]":"36.0","Cell RNA - MOLT-4 [nTPM]":"98.3","Cell RNA - NB-4 [nTPM]":"92.5","Cell RNA - NTERA-2 [nTPM]":"50.1","Cell RNA - OE19 [nTPM]":"38.0","Cell RNA - PC-3 [nTPM]":"38.0","Cell RNA - REH [nTPM]":"33.0","Cell RNA - RH-30 [nTPM]":"71.2","Cell RNA - RPMI-8226 [nTPM]":"56.1","Cell RNA - RPTEC TERT1 [nTPM]":"67.7","Cell RNA - RT4 [nTPM]":"35.2","Cell RNA - SCLC-21H [nTPM]":"57.6","Cell RNA - SH-SY5Y [nTPM]":"42.7","Cell RNA - SiHa [nTPM]":"42.7","Cell RNA - SK-BR-3 [nTPM]":"26.3","Cell RNA - SK-MEL-30 [nTPM]":"73.0","Cell RNA - SuSa [nTPM]":"59.5","Cell RNA - T-47d [nTPM]":"76.3","Cell RNA - THP-1 [nTPM]":"72.7","Cell RNA - TIME [nTPM]":"36.4","Cell RNA - U-138 MG [nTPM]":"25.2","Cell RNA - U-2 OS [nTPM]":"42.6","Cell RNA - U-2197 [nTPM]":"50.9","Cell RNA - U-251 MG [nTPM]":"54.3","Cell RNA - U-266\/70 [nTPM]":"41.3","Cell RNA - U-266\/84 [nTPM]":"57.6","Cell RNA - U-698 [nTPM]":"68.8","Cell RNA - U-87 MG [nTPM]":"54.6","Cell RNA - U-937 [nTPM]":"44.3","Cell RNA - WM-115 [nTPM]":"50.5","Blood RNA - basophil [nTPM]":"15.7","Blood RNA - classical monocyte [nTPM]":"14.5","Blood RNA - eosinophil [nTPM]":"10.3","Blood RNA - gdT-cell [nTPM]":"15.5","Blood RNA - intermediate monocyte [nTPM]":"11.3","Blood RNA - MAIT T-cell [nTPM]":"32.4","Blood RNA - memory B-cell [nTPM]":"22.6","Blood RNA - memory CD4 T-cell [nTPM]":"27.1","Blood RNA - memory CD8 T-cell [nTPM]":"21.5","Blood RNA - myeloid DC [nTPM]":"20.0","Blood RNA - naive B-cell [nTPM]":"21.6","Blood RNA - naive CD4 T-cell [nTPM]":"33.9","Blood RNA - naive CD8 T-cell [nTPM]":"27.6","Blood RNA - neutrophil [nTPM]":"7.9","Blood RNA - NK-cell [nTPM]":"23.8","Blood RNA - non-classical monocyte [nTPM]":"26.5","Blood RNA - plasmacytoid DC [nTPM]":"20.0","Blood RNA - T-reg [nTPM]":"27.2","Blood RNA - total PBMC [nTPM]":"17.2","Brain RNA - amygdala [nTPM]":"33.4","Brain RNA - basal ganglia [nTPM]":"34.9","Brain RNA - cerebellum [nTPM]":"33.6","Brain RNA - cerebral cortex [nTPM]":"43.1","Brain RNA - hippocampal formation [nTPM]":"33.9","Brain RNA - hypothalamus [nTPM]":"35.1","Brain RNA - medulla oblongata [nTPM]":"33.5","Brain RNA - midbrain [nTPM]":"34.0","Brain RNA - pons [nTPM]":"33.9","Brain RNA - spinal cord [nTPM]":"35.2","Brain RNA - thalamus [nTPM]":"33.4","Brain RNA - white matter [nTPM]":"35.6","Single Cell Type RNA - Adipocytes [nTPM]":"29.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"48.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"99.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"25.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"51.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"75.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"47.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"93.2","Single Cell Type RNA - dendritic cells [nTPM]":"58.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"88.0","Single Cell Type RNA - Ductal cells [nTPM]":"61.1","Single Cell Type RNA - Early spermatids [nTPM]":"222.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.9","Single Cell Type RNA - Endothelial cells [nTPM]":"32.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.5","Single Cell Type RNA - Erythroid cells [nTPM]":"33.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"51.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"98.5","Single Cell Type RNA - Fibroblasts [nTPM]":"30.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.3","Single Cell Type RNA - granulocytes [nTPM]":"34.2","Single Cell Type RNA - Granulosa cells [nTPM]":"48.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.4","Single Cell Type RNA - Hepatocytes [nTPM]":"30.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"67.4","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.8","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"49.4","Single Cell Type RNA - Langerhans cells [nTPM]":"36.7","Single Cell Type RNA - Late spermatids [nTPM]":"79.1","Single Cell Type RNA - Leydig cells [nTPM]":"37.0","Single Cell Type RNA - Macrophages [nTPM]":"34.6","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"66.6","Single Cell Type RNA - Muller glia cells [nTPM]":"42.5","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"60.9","Single Cell Type RNA - Paneth cells [nTPM]":"36.8","Single Cell Type RNA - Peritubular cells [nTPM]":"44.4","Single Cell Type RNA - Plasma cells [nTPM]":"32.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"47.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"88.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.3","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.5","Single Cell Type RNA - Spermatocytes [nTPM]":"179.1","Single Cell Type RNA - Spermatogonia [nTPM]":"71.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"77.2","Single Cell Type RNA - T-cells [nTPM]":"58.3","Single Cell Type RNA - Theca cells [nTPM]":"55.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.6","Single Cell Type RNA - Urothelial cells [nTPM]":"34.0"}]